Sample records for strong support system

  1. THE CAUSAL ANALYSIS / DIAGNOSIS DECISION INFORMATION SYSTEM (CADDIS) - 2007 UPDATE

    EPA Science Inventory

    CADDIS is an on-line decision support system that helps investigators in the regions, states and tribes find, access, organize, use and share information to produce causal evaluations in aquatic systems. It is based ...

  2. Valuing real estate externality-based option in development of transit system projects.

    DOT National Transportation Integrated Search

    2010-03-01

    Capital-intensive transit projects rely on strong public support and availability of funds. While the general : public has become a strong advocate for transit systems, budget shortfalls and financial constraints are still : resulting in delays in pr...

  3. Space nuclear power: Key to outer solar system exploration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bennett, G.L.; Allen, D.M.

    1998-07-01

    In 1995, in response to threatened budget cuts, the American Institute of Aeronautics and Astronautics (AIAA) approved a position paper supporting the maintenance of the technology base for space nuclear power. The position paper contained four recomemndations: (1) DOE, NASA, and DoD should develop and support an integrated program that maintains the nuclear option and develops the needed high-payoff technologies; (2) Congress should provide strong, continuing financial and political support for the agencies' program; (3) Government and industry leaders should voice their advocacy for a strong space nuclear power program to support future system requirements; and (4) The US shouldmore » continue to maintain its cooperation and technical interchanges with other countries to advance nuclear power source technology and to promote nuclear safety.« less

  4. Wearable smart systems: from technologies to integrated systems.

    PubMed

    Lymberis, A

    2011-01-01

    Wearable technology and integrated systems, so called Smart Wearable Systems (SWS) have demonstrated during the last 10-15 years significant advances in terms of, miniaturisation, seamless integration, data processing & communication, functionalisation and comfort. This is mainly due to the huge progress in sciences and technologies e.g. biomedical and micro & nano technologies, but also to a strong demand for new applications such as continuous personal health monitoring, healthy lifestyle support, human performance monitoring and support of professionals at risk. Development of wearable systems based of smart textile have, in addition, benefited from the eagerness of textile industry to develop new value-added apparel products like functionalized garments and smart clothing. Research and development in these areas has been strongly promoted worldwide. In Europe the major R&D activities were supported through the Information & Communication Technologies (ICT) priority of the R&D EU programs. The paper presents and discusses the main achievements towards integrated systems as well as future challenges to be met in order to reach a market with reliable and high value-added products.

  5. Social relationships and their biological correlates: Coronary Artery Risk Development in Young Adults (CARDIA) study.

    PubMed

    Seeman, Teresa E; Gruenewald, Tara L; Cohen, Sheldon; Williams, David R; Matthews, Karen A

    2014-05-01

    Analyses test the hypothesis that aspects of social relationships (quantity of ties, social support and social strain) are associated with differences in levels of biological risk across multiple major physiological regulatory systems and consequently overall multi-systems risk (i.e., allostatic load [AL]). Data are from the Coronary Artery Risk Development in Young Adults (CARDIA) study--a bi-ethnic, prospective, multi-center epidemiological study, initiated in 1985-1986 to track the development of cardiovascular risk in young adulthood (N=5115). At the year 15 follow-up when participants were between 32 and 45 years of age, additional social and biological data were collected; biological data used to assess AL were collected at the Oakland, CA and Chicago, IL sites (N=844). Social strains were most strongly and positively related to overall AL (Cohen's d=.79 for highest vs. lowest quartile), and to each of its component biological subsystems, independent of social ties and support as well as sociodemographics and health behaviors. Social ties and emotional support were also negatively related to AL (Cohen's d=.33 and d=.44 for lowest vs. highest quartiles of ties and support, respectively) though controls for social strains reduced these associations to non-significance. Social support and social strain were more strongly related to overall AL than to any of its component subscales while social ties were less strongly related to AL and to its component subscales. There was no evidence that effects differed by sex, age or ethnicity. Findings focus attention on the particularly strong relationship between social strains and profiles of biological risk and support the cumulative impact of social factors on biological risks, showing larger effects for cumulative AL than for any of the individual biological systems. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. Dyslexia: A Mother's Role

    ERIC Educational Resources Information Center

    Washburn, Erin K.

    2014-01-01

    Children and adolescents with dyslexia are at greater risk for academic failure and socioemotional problems than their non-dyslexic peers. However, researchers have suggested that individuals with dyslexia can benefit from a strong support system. Further, researchers have noted that mothers are integral to their child's support system. However,…

  7. Critical interactions between the Global Fund-supported HIV programs and the health system in Ghana.

    PubMed

    Atun, Rifat; Pothapregada, Sai Kumar; Kwansah, Janet; Degbotse, D; Lazarus, Jeffrey V

    2011-08-01

    The support of global health initiatives in recipient countries has been vigorously debated. Critics are concerned that disease-specific programs may be creating vertical and parallel service delivery structures that to some extent undermine health systems. This case study of Ghana aimed to explore how the Global Fund-supported HIV program interacts with the health system there and to map the extent and nature of integration of the national disease program across 6 key health systems functions. Qualitative interviews of national stakeholders were conducted to understand the perceptions of the strengths and weaknesses of the relationship between Global Fund-supported activities and the health system and to identify positive synergies and unintended consequences of integration. Ghana has a well-functioning sector-wide approach to financing its health system, with a strong emphasis on integrated care delivery. Ghana has benefited from US $175 million of approved Global Fund support to address the HIV epidemic, accounting for almost 85% of the National AIDS Control Program budget. Investments in infrastructure, human resources, and commodities have enabled HIV interventions to increase exponentially. Global Fund-supported activities have been well integrated into key health system functions to strengthen them, especially financing, planning, service delivery, and demand generation. Yet, with governance and monitoring and evaluation functions, parallel structures to national systems have emerged, leading to inefficiencies. This case study demonstrates that interactions and integration are highly varied across different health system functions, and strong government leadership has facilitated the integration of Global Fund-supported activities within national programs.

  8. Impact of configuration management system of computer center on support of scientific projects throughout their lifecycle

    NASA Astrophysics Data System (ADS)

    Bogdanov, A. V.; Iuzhanin, N. V.; Zolotarev, V. I.; Ezhakova, T. R.

    2017-12-01

    In this article the problem of scientific projects support throughout their lifecycle in the computer center is considered in every aspect of support. Configuration Management system plays a connecting role in processes related to the provision and support of services of a computer center. In view of strong integration of IT infrastructure components with the use of virtualization, control of infrastructure becomes even more critical to the support of research projects, which means higher requirements for the Configuration Management system. For every aspect of research projects support, the influence of the Configuration Management system is being reviewed and development of the corresponding elements of the system is being described in the present paper.

  9. Embedded-monolith armor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McElfresh, Michael W.; Groves, Scott E; Moffet, Mitchell L.

    2016-07-19

    A lightweight armor system utilizing a face section having a multiplicity of monoliths embedded in a matrix supported on low density foam. The face section is supported with a strong stiff backing plate. The backing plate is mounted on a spall plate.

  10. Assessing District Support for Leadership Development: Asking the Right Questions.

    ERIC Educational Resources Information Center

    Snow-Renner, Ravay

    This document provides guiding questions and a process for school district personnel to assess the district's organizational capacity for supporting strong educational leaders in a standards-based system. These questions reflect the most recent research literature about leadership and its optimal organizational supports in high-performing school…

  11. Tuning the photon statistics of a strongly coupled nanophotonic system

    NASA Astrophysics Data System (ADS)

    Dory, Constantin; Fischer, Kevin A.; Müller, Kai; Lagoudakis, Konstantinos G.; Sarmiento, Tomas; Rundquist, Armand; Zhang, Jingyuan L.; Kelaita, Yousif; Sapra, Neil V.; Vučković, Jelena

    2017-02-01

    We investigate the dynamics of single- and multiphoton emission from detuned strongly coupled systems based on the quantum-dot-photonic-crystal resonator platform. Transmitting light through such systems can generate a range of nonclassical states of light with tunable photon counting statistics due to the nonlinear ladder of hybridized light-matter states. By controlling the detuning between emitter and resonator, the transmission can be tuned to strongly enhance either single- or two-photon emission processes. Despite the strongly dissipative nature of these systems, we find that by utilizing a self-homodyne interference technique combined with frequency filtering we are able to find a strong two-photon component of the emission in the multiphoton regime. In order to explain our correlation measurements, we propose rate equation models that capture the dominant processes of emission in both the single- and multiphoton regimes. These models are then supported by quantum-optical simulations that fully capture the frequency filtering of emission from our solid-state system.

  12. The Research on the Framework of Healthy Water System Governance in Shandong Province

    NASA Astrophysics Data System (ADS)

    Liu, Fang; Li, Xiaomei; Min, Xianwei

    2018-02-01

    At present, the traditional water conservancy system in Shandong has created and exerted great social and economic benefits, but there are some kinds of obvious problems at the same time, for example, the water pollution is serious, the water conservancy project is not complete, the high and new technology is not widely used, the management system is not perfect, and the allocation of water resources is not reasonable, and so on. On the premise of absorbing the experience and lessons of traditional water conservancy, this paper discussed the main components of the framework of health water system in Shandong Province, and formed the four supporting systems of Shandong healthy water system. This study is not only of great practical significance to accelerate the transformation of traditional water resources to healthy water system in the whole province, provide strong support for the construction of strong economic and cultural province. At the same time, it also provides an important reference for the national healthy water system.

  13. How Smart Schools Get and Keep Community Support.

    ERIC Educational Resources Information Center

    Carroll, Susan Rovezzi; Carroll, David

    The purpose of this book is to provide public school systems with a fresh and unique approach to building community support. The book suggests that schools must build community support, discusses who the customers segments are, and outlines the diverse ways that public schools can begin to develop strong bonds with each customer segment. It…

  14. Reengineering health care: management systems for survivors.

    PubMed

    Griffith, J R

    1994-01-01

    To survive in the coming era, health care organizations must support the powerful concepts of continuous quality improvement with better internal management systems that include: (1) new processes for making decisions from mission to clinical guidelines; (2) hoshin planning, which emphasizes strong financial management and innovation to meet customer needs; (3) new organizations that make cross-disciplinary teams as important as traditional clinical support services; and (4) expanded information covering several new dimensions, including enhanced analytic capability, and supporting both traditional organization and cross-disciplinary teams.

  15. Solid strong base K-Pt/NaY zeolite nano-catalytic system for completed elimination of formaldehyde at room temperature

    NASA Astrophysics Data System (ADS)

    Song, Shaoqing; Wu, Xi; Lu, Changhai; Wen, Meicheng; Le, Zhanggao; Jiang, Shujuan

    2018-06-01

    Solid strong base nano-catalytic system of K-modification NaY zeolite supported 0.08% Pt (K-Pt/NaY) were constructed for eliminating HCHO at room temperature. In the catalytic process, activation energy over K-Pt/NaY nano-catalytic system was greatly decreased along with the enhanced reaction rate. Characterization and catalytic tests revealed the surface electron structure of K-Pt/NaY was improved, as reflected by the enhanced HCHO adsorption capability, high sbnd OH concentration, and low-temperature reducibility. Therefore, the optimal K-Pt/NaY showed high catalytic efficiency and strong H2O tolerance for HCHO elimination by directly promoting the reaction between active sbnd OH and formate species. These results may suggest a new way for probing the advanced solid strong base nano-catalytic system for the catalytic elimination of indoor HCHO.

  16. Dynamical observation and detailed description of catalysts under strong metal–support interaction

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Shuyi; Plessow, Philipp N.; Willis, Joshua J.

    2016-06-09

    Understanding the structures of catalysts under realistic conditions with atomic precision is crucial to design better materials for challenging transformations. Under reducing conditions, certain reducible supports migrate onto supported metallic particles and create strong metal–support states that drastically change the reactivity of the systems. The details of this process are still unclear and preclude its thorough exploitation. Here, we report an atomic description of a palladium/titania (Pd/TiO 2) system by combining state-of-the-art in situ transmission electron microscopy and density functional theory (DFT) calculations with structurally defined materials, in which we visualize the formation of the overlayers at the atomic scalemore » under atmospheric pressure and high temperature. We show that an amorphous reduced titania layer is formed at low temperatures, and that crystallization of the layer into either mono- or bilayer structures is dictated by the reaction environment and predicted by theory. Moreover, it occurs in combination with a dramatic reshaping of the metallic surface facets.« less

  17. Case Study: Austin Interfaith. Strong Neighborhoods, Strong Schools. The Indicators Project on Education Organizing.

    ERIC Educational Resources Information Center

    Simon, Elaine; Gold, Eva; Brown, Chris

    This report describes Austin, Texas' Austin Interfaith, which connects community institutions that can support families (e.g., schools, congregations, and civic organization) and builds the capacity of family members to participate fully in the economic system. Viewing schools as key neighborhood institutions, Austin Interfaith works directly with…

  18. Number Reading in Pure Alexia--A Review

    ERIC Educational Resources Information Center

    Starrfelt, Randi; Behrmann, Marlene

    2011-01-01

    It is commonly assumed that number reading can be intact in patients with pure alexia, and that this dissociation between letter/word recognition and number reading strongly constrains theories of visual word processing. A truly selective deficit in letter/word processing would strongly support the hypothesis that there is a specialized system or…

  19. Cooperation and Patience: The Key To A High Quality, Sustainable GIS

    DOT National Transportation Integrated Search

    1998-09-16

    Geographic Information Systems (GIS) provides a powerful tool to transportation : planners and engineers for a variety of analytical tasks. However, even with : the advent of PC-based GIS systems and strong state and federal support, : transportation...

  20. Near-infrared strong coupling between metamaterials and epsilon-near-zero modes in degenerately doped semiconductor nanolayers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Campione, Salvatore; Wendt, Joel R.; Keeler, Gordon Arthur

    Epsilon-near-zero (ENZ) modes provide a new path for tailoring light–matter interactions at the nanoscale. In this paper, we analyze a strongly coupled system at near-infrared frequencies comprising plasmonic metamaterial resonators and ENZ modes supported by degenerately doped semiconductor nanolayers. In strongly coupled systems that combine optical cavities and intersubband transitions, the polariton splitting (i.e., the ratio of Rabi frequency to bare cavity frequency) scales with the square root of the wavelength, thus favoring the long-wavelength regime. In contrast, we observe that the polariton splitting in ENZ/metamaterial resonator systems increases linearly with the thickness of the nanolayer supporting the ENZ modes.more » In this work, we employ an indium-tin-oxide nanolayer and observe a large experimental polariton splitting of approximately 30% in the near-infrared. As a result, this approach opens up many promising applications, including nonlinear optical components and tunable optical filters based on controlling the polariton splitting by adjusting the frequency of the ENZ mode.« less

  1. Near-infrared strong coupling between metamaterials and epsilon-near-zero modes in degenerately doped semiconductor nanolayers

    DOE PAGES

    Campione, Salvatore; Wendt, Joel R.; Keeler, Gordon Arthur; ...

    2016-01-14

    Epsilon-near-zero (ENZ) modes provide a new path for tailoring light–matter interactions at the nanoscale. In this paper, we analyze a strongly coupled system at near-infrared frequencies comprising plasmonic metamaterial resonators and ENZ modes supported by degenerately doped semiconductor nanolayers. In strongly coupled systems that combine optical cavities and intersubband transitions, the polariton splitting (i.e., the ratio of Rabi frequency to bare cavity frequency) scales with the square root of the wavelength, thus favoring the long-wavelength regime. In contrast, we observe that the polariton splitting in ENZ/metamaterial resonator systems increases linearly with the thickness of the nanolayer supporting the ENZ modes.more » In this work, we employ an indium-tin-oxide nanolayer and observe a large experimental polariton splitting of approximately 30% in the near-infrared. As a result, this approach opens up many promising applications, including nonlinear optical components and tunable optical filters based on controlling the polariton splitting by adjusting the frequency of the ENZ mode.« less

  2. Evolution and Evaluation of ECG Interpretation Systems-An Illustration of the Validation of Decision Support Systems

    PubMed Central

    van Bemmel, Jan H.; Kors, Jan A.; Willems, Jos L.; van Herpen, Gerard

    1990-01-01

    The last decade has shown a growing interest in medical decision making, strongly stimulated by the advent of artificial intelligence. This wave of interest is not the first one; it was preceded by other models and approaches to medical decision support. However, not all developments have resulted in equally successful decision support systems. Positive exceptions are the interpretation systems for ECGs that evolved all the way from very primitive attempts to well-accepted and highly-computerized clinical systems for which a major evaluation study (CSE, Common Standards for Quantitative Electrocardiography) is finalized in 1990. The evolution and the evaluation of the systems that took part in this study, is the subject of this paper.

  3. RTEMS CENTRE- Support and Maintenance CENTRE to RTEMS Operating System

    NASA Astrophysics Data System (ADS)

    Silva, H.; Constantino, A.; Coutunho, M.; Freitas, D.; Faustino, S.; Mota, M.; Colaço, P.; Zulianello, M.

    2008-08-01

    RTEMS stands for Real-Time Operating System for Multiprocessor Systems. It is a full featured Real Time Operating System that supports a variety of open APIs and interface standards. It provides a high performance environment for embedded applications, including a fixed-priority preemptive/non-preemptive scheduler, a comprehensive set of multitasking operations and a large range of supported architectures. Support and maintenance CENTRE to RTEMS operating system (RTEMS CENTRE) is a joint initiative of ESA-Portugal Task force, aiming to build a strong technical competence in the space flight (on- board) software, to offer support, maintenance and improvements to RTEMS. This paper provides a high level description of the current and future activities of the RTEMS CENTRE. It presents a brief description of the RTEMS operating system, a description of the tools developed and distributed to the community [1] and the improvements to be made to the operating system, including facilitation for the qualification of RTEMS (4.8.0) [2] for the space missions.

  4. Hypothesis-confirming information search strategies and computerized information-retrieval systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jacobs, S.M.

    A recent trend in information-retrieval systems technology is the development of on-line information retrieval systems. One objective of these systems has been to attempt to enhance decision effectiveness by allowing users to preferentially seek information, thereby facilitating the reduction or elimination of information overload. These systems do not necessarily lead to more-effective decision making, however. Recent research in information-search strategy suggests that when users are seeking information subsequent to forming initial beliefs, they may preferentially seek information to confirm these beliefs. It seems that effective computer-based decision support requires an information retrieval system capable of: (a) retrieving a subset ofmore » all available information, in order to reduce information overload, and (b) supporting an information search strategy that considers all relevant information, rather than merely hypothesis-confirming information. An information retrieval system with an expert component (i.e., a knowledge-based DSS) should be able to provide these capabilities. Results of this study are non conclusive; there was neither strong confirmatory evidence nor strong disconfirmatory evidence regarding the effectiveness of the KBDSS.« less

  5. Family members facilitating community re-integration and return to productivity following traumatic brain injury - motivations, roles and challenges.

    PubMed

    Gagnon, Alicia; Lin, Jenny; Stergiou-Kita, Mary

    2016-01-01

    This study explores the experiences of family members in supporting community re-integration and return to productive occupations of the traumatic brain injury (TBI) survivor in order to: (i) describe family members' supportive roles, (ii) determine challenges family members experience in supporting the TBI survivor; and (iii) identify supports that family members require to maintain and enhance their roles. This qualitative descriptive study involved 14 interviews with immediate family members of TBI survivors. Data was analyzed using thematic analysis. Family members expressed strong motivation and engaged in six key roles to support TBI survivors: researcher, case manager, advocate, coach, activities of daily living (ADL)/instrumental ADLs and emotional supporter. Personal and family stressors and challenges navigating the health care system were perceived as challenges in meeting demands of their supportive roles. Stigma also presented a barrier to successful community and vocational re-integration. Subsequently, family members desired more education related to the functional implications of TBI, to be connected to health care and community resources, and sought a greater family-centred care approach. Family members require on-going counseling and community supports to prevent burnout and allow for their continued engagement in their supportive roles. Further education on how to navigate the health care system, access community programs and rights to workplace accommodation is also warranted. Family members are strongly motivated to support survivors' return to productive occupation following a traumatic brain injury, but require counseling and community support to enable their on-going engagement and prevent burnout. Family members can be further empowered through the implementation of family-centred care. Family members requested further education on the long-term functional implications of TBI, how to navigate the health care system, how to access community programs and workers' rights to workplace accommodations.

  6. PREFACE: Strongly Coupled Coulomb Systems Strongly Coupled Coulomb Systems

    NASA Astrophysics Data System (ADS)

    Neilson, David; Senatore, Gaetano

    2009-05-01

    This special issue contains papers presented at the International Conference on Strongly Coupled Coulomb Systems (SCCS), held from 29 July-2 August 2008 at the University of Camerino. Camerino is an ancient hill-top town located in the Apennine mountains of Italy, 200 kilometres northeast of Rome, with a university dating back to 1336. The Camerino conference was the 11th in a series which started in 1977: 1977: Orleans-la-Source, France, as a NATO Advanced Study Institute on Strongly Coupled Plasmas (hosted by Marc Feix and Gabor J Kalman) 1982: Les Houches, France (hosted by Marc Baus and Jean-Pierre Hansen) 1986: Santa Cruz, California, USA (hosted by Forrest J Rogers and Hugh E DeWitt) 1989: Tokyo, Japan (hosted by Setsuo Ichimaru) 1992: Rochester, New York, USA (hosted by Hugh M Van Horn and Setsuo Ichimaru) 1995: Binz, Germany (hosted by Wolf Dietrich Kraeft and Manfred Schlanges) 1997: Boston, Massachusetts, USA (hosted by Gabor J Kalman) 1999: St Malo, France (hosted by Claude Deutsch and Bernard Jancovici) 2002: Santa Fe, New Mexico, USA (hosted by John F Benage and Michael S Murillo) 2005: Moscow, Russia (hosted by Vladimir E Fortov and Vladimir Vorob'ev). The name of the series was changed in 1996 from Strongly Coupled Plasmas to Strongly Coupled Coulomb Systems to reflect a wider range of topics. 'Strongly Coupled Coulomb Systems' encompasses diverse many-body systems and physical conditions. The purpose of the conferences is to provide a regular international forum for the presentation and discussion of research achievements and ideas relating to a variety of plasma, liquid and condensed matter systems that are dominated by strong Coulomb interactions between their constituents. Each meeting has seen an evolution of topics and emphases that have followed new discoveries and new techniques. The field has continued to see new experimental tools and access to new strongly coupled conditions, most recently in the areas of warm matter, dusty plasmas, condensed matter and ultra-cold plasmas. One hundred and thirty participants came from twenty countries and four continents to participate in the conference. Those giving presentations were asked to contribute to this special issue to make a representative record of an interesting conference. We thank the International Advisory Board and the Programme Committee for their support and suggestions. We thank the Local Organizing Committee (Stefania De Palo, Vittorio Pellegrini, Andrea Perali and Pierbiagio Pieri) for all their efforts. We highlight for special mention the dedication displayed by Andrea Perali, by Rocco di Marco for computer support, and by our tireless conference secretary Fiorella Paino. The knowledgeable guided tour of the historic centre of Camerino given by Fiorella Paino was appreciated by many participants. It is no exaggeration to say that without the extraordinary efforts put in by these three, the conference could not have been the success that it was. For their sustained interest and support we thank Fulvio Esposito, Rector of the University of Camerino, Fabio Beltram, Director of NEST, Scuola Normale Superiore, Pisa, and Daniel Cox, Co-Director of ICAM, University of California at Davis. We thank the Institute of Complex and Adaptive Matter ICAM-I2CAM, USA for providing a video record of the conference on the web (found at http://sccs2008.df.unicam.it/). Finally we thank the conference sponsors for their very generous support: the University of Camerino, the Institute of Complex and Adaptive Matter ICAM-I2CAM, USA, the International Centre for Theoretical Physics ICTP Trieste, and CNR-INFM DEMOCRITOS Modeling Center for Research in Atomistic Simulation, Trieste. Participants at the International Conference on Strongly Coupled Coulomb Systems (SCCS) (University of Camerino, Italy, 29 July-2 August 2008).

  7. Devolving HRM and HRD to Line managers: The Case of Hilton International's UK Hotels

    ERIC Educational Resources Information Center

    Maxwell, Gillian; Watson, Sandra

    2004-01-01

    This paper explores line manager responsibility for human resource management (HRM) and human resource development (HRD) in an international hotel organisation. The results identify a strong support system for line managers in relation to training and good relations with HR specialists. However, less evident is senior management support coupled…

  8. Using Brief Experimental Analysis to Intensify Tier 3 Reading Interventions

    ERIC Educational Resources Information Center

    Coolong-Chaffin, Melissa; Wagner, Dana

    2015-01-01

    As implementation of multi-tiered systems of support becomes common practice across the nation, practitioners continue to need strategies for intensifying interventions and supports for the subset of students who fail to make adequate progress despite strong programs at Tiers 1 and 2. Experts recommend making several changes to the structure and…

  9. Teenage Pregnancy

    MedlinePlus

    ... Life Family Life Family Life Medical Home Family Dynamics Media Work & Play Getting Involved in Your Community ... she may need help identifying a strong support system. Teens and young girls who have babies can ...

  10. Materials Research Capabilities

    NASA Technical Reports Server (NTRS)

    Stofan, Andrew J.

    1986-01-01

    Lewis Research Center, in partnership with U.S. industry and academia, has long been a major force in developing advanced aerospace propulsion and power systems. One key aspect that made many of these systems possible has been the availability of high-performance, reliable, and long-life materials. To assure a continuing flow of new materials and processing concepts, basic understanding to guide such innovation, and technological support for development of major NASA systems, Lewis has supported a strong in-house materials research activity. Our researchers have discovered new alloys, polymers, metallic composites, ceramics, coatings, processing techniques, etc., which are now also in use by U.S. industry. This brochure highlights selected past accomplishments of our materials research and technology staff. It also provides many examples of the facilities available with which we can conduct materials research. The nation is now beginning to consider integrating technology for high-performance supersonic/hypersonic aircraft, nuclear space power systems, a space station, and new research areas such as materials processing in space. As we proceed, I am confident that our materials research staff will continue to provide important contributions which will help our nation maintain a strong technology position in these areas of growing world competition. Lewis Research Center, in partnership with U.S. industry and academia, has long been a major force in developing advanced aerospace propulsion and power systems. One key aspect that made many of these systems possible has been the availability of high-performance, reliable, and long-life materials. To assure a continuing flow of new materials and processing concepts, basic understanding to guide such innovation, and technological support for development of major NASA systems, Lewis has supported a strong in-house materials research activity. Our researchers have discovered new alloys, polymers, metallic composites, ceramics, coatings, processing techniques, etc., which are now also in use by U.S. industry. This brochure highlights selected past accomplishments of our materials research and technology staff. It also provides many examples of the facilities available with which we can conduct materials research. The nation is now beginning to consider integrating technology for high-performance supersonic/hypersonic aircraft, nuclear space power systems, a space station, and new research areas such as materials processing in space.

  11. Chemical and microbiological experimentation for development of environmental control and life support systems

    NASA Technical Reports Server (NTRS)

    Whitman, G. A.; Wilson, M. E.; Cole, H. E.; Traweek, M.

    1992-01-01

    Microbiological techniques are under study with a view to the identification of viable microorganisms in liquid cultures, improve the identification of stressed organisms, and determine the biocidal activity of iodine and other chemicals on isolates from recycled water. A quality-assurance program has been implemented to validate data employed in making decisions concerning engineering and human health and safety. Analytical laboratory refinements will strongly aid the development of environmental control and life-support systems.

  12. Life support for aquatic species - past; present; future

    NASA Astrophysics Data System (ADS)

    Slenzka, K.

    Life Support is a basic issue since manned space flight began. Not only to support astronauts and cosmonauts with the essential things to live, however, also animals which were carried for research to space etc together with men need support systems to survive under space conditions. Most of the animals transported to space participate at the life support system of the spacecraft. However, aquatic species live in water as environment and thus need special developments. Research with aquatic animals has a long tradition in manned space flight resulting in numerous life support systems for them starting with simple plastic bags up to complex support hardware. Most of the recent developments have to be identified as part of a technological oriented system and can be described as small technospheres. As the importance arose to study our Earth as the extraordinary Biosphere we live in, the modeling of small ecosystems began as part of ecophysiological research. In parallel the investigations of Bioregenerative Life Support Systems were launched and identified as necessity for long-term space missions or traveling to Moon and Mars and beyond. This paper focus on previous developments of Life Support Systems for aquatic animals and will show future potential developments towards Bioregenerative Life Support which additionally strongly benefits to our Earth's basic understanding.

  13. Pascal Liquid Phase in Electronic Waveguides

    NASA Astrophysics Data System (ADS)

    Tomczyk, M.; Briggeman, M.; Tylan-Tyler, A.; Huang, M.; Tian, B.; Pekker, D.; Lee, J.-W.; Lee, H.; Eom, C.-B.; Levy, J.

    Clean one-dimensional electron transport has been observed in very few material systems. The development of exceptionally clean electron waveguides formed at the interface between complex oxides LaAlO3 and SrTiO3 enables low-dimensional transport to be explored with newfound flexibility. This material system not only supports ballistic 1D transport, but possesses a rich phase diagram and strong attractive electron-electron interactions which are not present in other solid-state systems. Here we report an unusual phenomenon in which quantized conductance increases by steps that themselves increase sequentially in multiples of e2 / h . The overall conductance exhibits a Pascal-like sequence: 1, 3, 6, 10... e2 / h , which we ascribe to ballistic transport of 1, 2, 3, 4 ... bunches of electrons. We will discuss how subband degeneracies can occur in non-interacting models that have carefully tuned parameters. Strong attractive interactions are required, however, for these subbands to lock together. This Pascal liquid phase provides a striking example of the consequences of strong attractive interactions in low-dimensional environments. We gratefully acknowledge financial support from AFOSR (FA9550-12-1- 0057 (JL) and FA9550-12-1-0342 (CBE)), ONR N00014-15-1-2847 (JL), and NSF DMR-1234096 (CBE).

  14. Strong FANCA/FANCG but weak FANCA/FANCC interaction in the yeast 2-hybrid system.

    PubMed

    Reuter, T; Herterich, S; Bernhard, O; Hoehn, H; Gross, H J

    2000-01-15

    Three of at least 8 Fanconi anemia (FA) genes have been cloned (FANCA, FANCC, FANCG), but their functions remain unknown. Using the yeast 2-hybrid system and full-length cDNA, the authors found a strong interaction between FANCA and FANCG proteins. They also obtained evidence for a weak interaction between FANCA and FANCC. Neither FANCA nor FANCC was found to interact with itself. These results support the notion of a functional association between the FA gene products. (Blood. 2000;95:719-720)

  15. A note on the blind deconvolution of multiple sparse signals from unknown subspaces

    NASA Astrophysics Data System (ADS)

    Cosse, Augustin

    2017-08-01

    This note studies the recovery of multiple sparse signals, xn ∈ ℝL, n = 1, . . . , N, from the knowledge of their convolution with an unknown point spread function h ∈ ℝL. When the point spread function is known to be nonzero, |h[k]| > 0, this blind deconvolution problem can be relaxed into a linear, ill-posed inverse problem in the vector concatenating the unknown inputs xn together with the inverse of the filter, d ∈ ℝL where d[k] := 1/h[k]. When prior information is given on the input subspaces, the resulting overdetermined linear system can be solved efficiently via least squares (see Ling et al. 20161). When no information is given on those subspaces, and the inputs are only known to be sparse, it still remains possible to recover these inputs along with the filter by considering an additional l1 penalty. This note certifies exact recovery of both the unknown PSF and unknown sparse inputs, from the knowledge of their convolutions, as soon as the number of inputs N and the dimension of each input, L , satisfy L ≳ N and N ≳ T2max, up to log factors. Here Tmax = maxn{Tn} and Tn, n = 1, . . . , N denote the supports of the inputs xn. Our proof system combines the recent results on blind deconvolution via least squares to certify invertibility of the linear map encoding the convolutions, with the construction of a dual certificate following the structure first suggested in Candés et al. 2007.2 Unlike in these papers, however, it is not possible to rely on the norm ||(A*TAT)-1|| to certify recovery. We instead use a combination of the Schur Complement and Neumann series to compute an expression for the inverse (A*TAT)-1. Given this expression, it is possible to show that the poorly scaled blocks in (A*TAT)-1 are multiplied by the better scaled ones or vanish in the construction of the certificate. Recovery is certified with high probablility on the choice of the supports and distribution of the signs of each input xn on the support. The paper follows the line of previous work by Wang et al. 20163 where the authors guarantee recovery for subgaussian × Bernoulli inputs satisfying 𝔼xn|k| ∈ [1/10, 1] as soon as N ≳ L. Examples of applications include seismic imaging with unknown source or marine seismic data deghosting, magnetic resonance autocalibration or multiple channel estimation in communication. Numerical experiments are provided along with a discussion on the sample complexity tightness.

  16. Factors Affecting Educational Innovation with in Class Electronic Response Systems

    ERIC Educational Resources Information Center

    Freeman, Mark; Bell, Amani; Comerton-Forde, Carole; Pickering, Joanne; Blayney, Paul

    2007-01-01

    This paper reports the use of Rogers' diffusion of innovation perspective to understand the factors affecting educational innovation decisions, specifically in regard to in class electronic response systems. Despite decreasing costs and four decades of research showing strong student support, academic adoption is limited. Using data collected from…

  17. [Transverse folding and the evolution of hind wings in beetles (Insecta, Coleoptera)].

    PubMed

    Fedorenko, D N

    2013-01-01

    Strong intensification of the protective function of the fore wing in Coleoptera has made their flight apparatus a posteromotoric one and invited an apparatus responsible for folding the hindwings beneath the elytra to develop. Folding apparatus could hardly develop without higher deformability of veins or their parts, which diminished strength properties of the wing support. The effect was stressed by folds that intersected veins. Organization of the folds into a system confined this negative influence to a few wing regions and some veinal sections. This having happened, wing support and folding pattern evolved interrelated, the former into being more flexible, with no or minimum loss of rigidity, and the latter towards being less harmful for the supporting elements, especially axial ones. Monofunctionality, together with very simple structure and little specialization of constituent parts, made the folding pattern very labile during evolution. The folding pattern evolved more rapidly than wing venation, thus defining transformations of the latter. Evolutionary conservatism of wing venation stemmed from that many veins were strongly specialized in performing two conflicting functions. An adaptive compromise was necessary for the conflict to be solved, which determined the wing to orthogenetic development. The main evolutionary trends for wing venation and folding pattern were those towards simplification and a higher complexity, respectively. The beetle wing has passed through two main evolutionary stages. Among them, the first resulted in the development of the "Archostemata" wing type, the second started from the "cantharoid" structural plan. The main evolutionary factors were the infancies of wing posteromotorism at the first stage while the wing strongly influenced by size evolution, with the main trend towards miniaturization, at the second. The archostematan and "cantharoid" morphofunctional wing types differ fundamentally. In the wing of the former kind, folding and flight apparatus, because of considerably overlapping supporting systems, constitute a lasting coadaptive ensemble, with only minor deviations from the ground-plan occurring through evolution. The uprise of the "cantharoid" wing type was an upgrade of morpho-functional organization. The region of maximum transverse deformations having been extruded from the remigium basal part, chief supporting axes of the wing increased their rigid properties. The supporting systems of the two wing apparatus became more autonomous, having been separated. This expanded the adaptive zone for the wing strongly, which a great variety of derived wing types have emerged from.

  18. Understanding the implementation and adoption of an information technology intervention to support medicine optimisation in primary care: qualitative study using strong structuration theory.

    PubMed

    Jeffries, Mark; Phipps, Denham; Howard, Rachel L; Avery, Anthony; Rodgers, Sarah; Ashcroft, Darren

    2017-05-10

    Using strong structuration theory, we aimed to understand the adoption and implementation of an electronic clinical audit and feedback tool to support medicine optimisation for patients in primary care. This is a qualitative study informed by strong structuration theory. The analysis was thematic, using a template approach. An a priori set of thematic codes, based on strong structuration theory, was developed from the literature and applied to the transcripts. The coding template was then modified through successive readings of the data. Clinical commissioning group in the south of England. Four focus groups and five semi-structured interviews were conducted with 18 participants purposively sampled from a range of stakeholder groups (general practitioners, pharmacists, patients and commissioners). Using the system could lead to improved medication safety, but use was determined by broad institutional contexts; by the perceptions, dispositions and skills of users; and by the structures embedded within the technology. These included perceptions of the system as new and requiring technical competence and skill; the adoption of the system for information gathering; and interactions and relationships that involved individual, shared or collective use. The dynamics between these external, internal and technological structures affected the adoption and implementation of the system. Successful implementation of information technology interventions for medicine optimisation will depend on a combination of the infrastructure within primary care, social structures embedded in the technology and the conventions, norms and dispositions of those utilising it. Future interventions, using electronic audit and feedback tools to improve medication safety, should consider the complexity of the social and organisational contexts and how internal and external structures can affect the use of the technology in order to support effective implementation. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  19. Swarming Unmanned Aircraft Systems

    DTIC Science & Technology

    2008-09-01

    systems may become a viable part of strategy and tactics in the future. Specific to Unmanned Aircraft Sys- tems ( UAS ). they see a strong and central...system itself. They do not want to limit direct access to only Military Occupational Specialty (MOS) trained UAS operators. Rather, they feel that...Collaborating (SASC) characteristics within swarms of UAS that support operations. Technical Approach The approach taken to model this system begins with an

  20. Tuning the Photon Statistics of a Strongly Coupled Nanophotonic System

    NASA Astrophysics Data System (ADS)

    Dory, C.; Fischer, K. A.; Müller, K.; Lagoudakis, K. G.; Sarmiento, T.; Rundquist, A.; Zhang, J. L.; Kelaita, Y.; Sapra, N. V.; Vučković, J.

    Strongly coupled quantum-dot-photonic-crystal cavity systems provide a nonlinear ladder of hybridized light-matter states, which are a promising platform for non-classical light generation. The transmission of light through such systems enables light generation with tunable photon counting statistics. By detuning the frequencies of quantum emitter and cavity, we can tune the transmission of light to strongly enhance either single- or two-photon emission processes. However, these nanophotonic systems show a strongly dissipative nature and classical light obscures any quantum character of the emission. In this work, we utilize a self-homodyne interference technique combined with frequency-filtering to overcome this obstacle. This allows us to generate emission with a strong two-photon component in the multi-photon regime, where we measure a second-order coherence value of g (2) [ 0 ] = 1 . 490 +/- 0 . 034 . We propose rate equation models that capture the dominant processes of emission both in the single- and multi-photon regimes and support them by quantum-optical simulations that fully capture the frequency filtering of emission from our solid-state system. Finally, we simulate a third-order coherence value of g (3) [ 0 ] = 0 . 872 +/- 0 . 021 . Army Research Office (ARO) (W911NF1310309), National Science Foundation (1503759), Stanford Graduate Fellowship.

  1. Caring for each other: how do nurse managers 'manage' their role?

    PubMed

    Paliadelis, Penny; Cruickshank, Mary; Sheridan, Alison

    2007-11-01

    This article will report on one aspect of a larger study that explored the working lives of nursing unit managers in Australia. The support of nursing unit managers is the focus of this article. There is evidence in the recent literature that nurses are not generally supportive of each other and that nursing unit managers are not adequately supported to manage their expanding administrative and managerial responsibilities. A qualitative feminist approach was used to conduct individual interviews with 20 nursing unit managers employed in the public healthcare system in Australia. The results indicated that participants did not feel supported by the wider organization, but gained support from within their own ranks. The results showed a strong support system within the participant group, despite evidence in the literature that nurses, generally, are not supportive of each other. The results of this study may be used in the development of more effective support mechanisms for nurse managers.

  2. A quantitative framework to evaluate modeling of cortical development by neural stem cells

    PubMed Central

    Stein, Jason L.; de la Torre-Ubieta, Luis; Tian, Yuan; Parikshak, Neelroop N.; Hernandez, Israel A.; Marchetto, Maria C.; Baker, Dylan K.; Lu, Daning; Hinman, Cassidy R.; Lowe, Jennifer K.; Wexler, Eric M.; Muotri, Alysson R.; Gage, Fred H.; Kosik, Kenneth S.; Geschwind, Daniel H.

    2014-01-01

    Summary Neural stem cells have been adopted to model a wide range of neuropsychiatric conditions in vitro. However, how well such models correspond to in vivo brain has not been evaluated in an unbiased, comprehensive manner. We used transcriptomic analyses to compare in vitro systems to developing human fetal brain and observed strong conservation of in vivo gene expression and network architecture in differentiating primary human neural progenitor cells (phNPCs). Conserved modules are enriched in genes associated with ASD, supporting the utility of phNPCs for studying neuropsychiatric disease. We also developed and validated a machine learning approach called CoNTExT that identifies the developmental maturity and regional identity of in vitro models. We observed strong differences between in vitro models, including hiPSC-derived neural progenitors from multiple laboratories. This work provides a systems biology framework for evaluating in vitro systems and supports their value in studying the molecular mechanisms of human neurodevelopmental disease. PMID:24991955

  3. Observation of Mollow Triplets with Tunable Interactions in Double Lambda Systems of Individual Hole Spins.

    NASA Astrophysics Data System (ADS)

    Lagoudakis, K. G.; Fischer, K. A.; Sarmiento, T.; McMahon, P. L.; Radulaski, M.; Zhang, J. L.; Kelaita, Y.; Dory, C.; Mueller, K. M.; Vuckovic, J.

    Although individual spins in quantum dots have been extensively used as qubits, their investigation under strong resonant driving in view of accessing Mollow physics is still an open question. We have grown high quality positively charged quantum dots (QD) embedded in a planar microcavity that enable enhanced light matter interactions. Applying a strong magnetic field in the Voigt configuration, individual positively charged quantum dots provide a double lambda level structure. Using a combination of above band and resonant excitation, we observe the formation of Mollow triplets. We investigate the regime where the Mollow sideband splittings are equal to the Zeeman splitting; we observe strong interactions between the Mollow sidebands of the inner transitions and the outer transitions in the form of very clear anticrossings. We investigated these anticrossings and we were able to modify the observed anticrossing splittings on demand by rotating the polarization of the resonant laser. We also developed a quantum-optical model of our system that fully captures the experimentally observed spectra and provides insight on the complicated level structure that results from the strong driving of our positively charged quantum dot. The authors acknowledge financial support from the Army Research Office (Grant No. W911NF1310309) and support from the National Science Foundation, Division of Materials Research (Grant No. 1503759).

  4. ORAC: a modern observing system for UKIRT

    NASA Astrophysics Data System (ADS)

    Bridger, Alan; Wright, Gillian S.; Economou, Frossie; Tan, Min; Currie, Malcolm J.; Pickup, David A.; Adamson, Andrew J.; Rees, Nicholas P.; Purves, Maren; Kackley, Russell

    2000-06-01

    The steady improvement in telescope performance at UKIRT and the increase in data acquisition rates led to a strong desired for an integrated observing framework that would meet the needs of future instrumentation, as well as providing some support for existing instrumentation. Thus the Observatory Reduction and Acquisition Control (ORAC) project was created in 1997 with the goals of improving the scientific productivity in the telescope, reducing the overall ongoing support requirements, and eventually supporting the use of more flexibly scheduled observing. The project was also expected to achieve this within a tight resource allocation. In October 1999 the ORAC system was commissioned at the United Kingdom Infrared Telescope.

  5. A New Measurement and Ranking System for the UK National Student Survey

    ERIC Educational Resources Information Center

    Canning, John

    2015-01-01

    Despite numerous criticisms of the UK National Student Survey (NSS) institutional managers still strongly support its use in informing student choice, quality and assurance and quality enhancement activities. This article outlines a granular and nuanced benchmarking system for the NSS which provides both a "raw" score (weighted student…

  6. WLAN Positioning Methods and Supporting Learning Technologies for Mobile Platforms

    ERIC Educational Resources Information Center

    Melkonyan, Arsen

    2013-01-01

    Location technologies constitute an essential component of systems design for autonomous operations and control. The Global Positioning System (GPS) works well in outdoor areas, but the satellite signals are not strong enough to penetrate inside most indoor environments. As a result, a new strain of indoor positioning technologies that make use of…

  7. Comparison of Two Sources of Clinical Audit Data to Assess the Delivery of Diabetes Care in Aboriginal Communities.

    PubMed

    Regan, Timothy; Paul, Christine; Ishiguchi, Paul; D'Este, Catherine; Koller, Claudia; Forshaw, Kristy; Noble, Natasha; Oldmeadow, Christopher; Bisquera, Alessandra; Eades, Sandra

    2017-10-17

    The objective of this study was to determine the concordance between data extracted from two Clinical Decision Support Systems regarding diabetes testing and monitoring at Aboriginal Community Controlled Health Services in Australia. De-identified PenCAT and Communicare Systems data were extracted from the services allocated to the intervention arm of a diabetes care trial, and intra-class correlations for each extracted item were derived at a service level. Strong to very strong correlations between the two data sources were found regarding the total number of patients with diabetes per service (Intra-class correlation [ICC] = 0.99), as well as the number (ICC = 0.98-0.99) and proportion (ICC = 0.96) of patients with diabetes by gender. The correlation was moderate for the number and proportion of Type 2 diabetes patients per service in the group aged 18-34 years (ICC = 0.65 and 0.8-0.82 respectively). Strong to very strong correlations were found for numbers and proportions of patients being tested for diabetes, and for appropriate monitoring of patients known to have diabetes (ICC = 0.998-1.00). This indicated a generally high degree of concordance between whole-service data extracted by the two Clinical Decision Support Systems. Therefore, the less expensive or less complex option (depending on the individual circumstances of the service) may be appropriate for monitoring diabetes testing and care. However, the extraction of data about subgroups of patients may not be interchangeable.

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cooperstock, F.I., E-mail: cooperst@uvic.ca; Dupre, M.J., E-mail: mdupre@tulane.edu

    We introduce a naturally-defined totally invariant spacetime energy expression for general relativity incorporating the contribution from gravity. The extension links seamlessly to the action integral for the gravitational field. The demand that the general expression for arbitrary systems reduces to the Tolman integral in the case of stationary bounded distributions, leads to the matter-localized Ricci integral for energy–momentum in support of the energy localization hypothesis. The role of the observer is addressed and as an extension of the special relativistic case, the field of observers comoving with the matter is seen to compute the intrinsic global energy of a system.more » The new localized energy supports the Bonnor claim that the Szekeres collapsing dust solutions are energy-conserving. It is suggested that in the extreme of strong gravity, the Heisenberg Uncertainty Principle be generalized in terms of spacetime energy–momentum. -- Highlights: •We present a totally invariant spacetime energy expression for general relativity incorporating the contribution from gravity. •Demand for the general expression to reduce to the Tolman integral for stationary systems supports the Ricci integral as energy–momentum. •Localized energy via the Ricci integral is consistent with the energy localization hypothesis. •New localized energy supports the Bonnor claim that the Szekeres collapsing dust solutions are energy-conserving. •Suggest the Heisenberg Uncertainty Principle be generalized in terms of spacetime energy–momentum in strong gravity extreme.« less

  9. The 2011 mileage-based user fee symposium.

    DOT National Transportation Integrated Search

    2011-09-01

    "The fuel tax is rapidly losing its ability to support system needs. Federal environmental : regulations and the escalating price of fossil fuels have created a strong incentive to develop and : utilize more fuel-efficient vehicles, which will drive ...

  10. Advanced cathode materials for polymer electrolyte fuel cells based on pt/ metal oxides: from model electrodes to catalyst systems.

    PubMed

    Fabbri, Emiliana; Pătru, Alexandra; Rabis, Annett; Kötz, Rüdiger; Schmidt, Thomas J

    2014-01-01

    The development of stable catalyst systems for application at the cathode side of polymer electrolyte fuel cells (PEFCs) requires the substitution of the state-of-the-art carbon supports with materials showing high corrosion resistance in a strongly oxidizing environment. Metal oxides in their highest oxidation state can represent viable support materials for the next generation PEFC cathodes. In the present work a multilevel approach has been adopted to investigate the kinetics and the activity of Pt nanoparticles supported on SnO2-based metal oxides. Particularly, model electrodes made of SnO2 thin films supporting Pt nanoparticles, and porous catalyst systems made of Pt nanoparticles supported on Sb-doped SnO2 high surface area powders have been investigated. The present results indicate that SnO2-based supports do not modify the oxygen reduction reaction mechanism on the Pt nanoparticle surface, but rather lead to catalysts with enhanced specific activity compared to Pt/carbon systems. Different reasons for the enhancement in the specific activity are considered and discussed.

  11. Switching skeletons: hydrostatic support in molting crabs

    NASA Technical Reports Server (NTRS)

    Taylor, Jennifer R A.; Kier, William M.; Walker, I. D. (Principal Investigator)

    2003-01-01

    Skeletal support systems are essential for support, movement, muscular antagonism, and locomotion. Crustaceans shed their rigid exoskeleton at each molt yet are still capable of forceful movement. We hypothesize that the soft water-inflated body of newly molted crabs may rely on a hydrostatic skeleton, similar to that of worms and polyps. We measured internal hydrostatic pressure and the force exerted during claw adduction and observed a strong correlation between force and hydrostatic pressure, consistent with hydrostatic skeletal support. This alternation between the two basic skeletal types may be widespread among arthropods.

  12. High-resolution spectroscopy of the CN red system in comet C/2013 R1 (Lovejoy) using WINERED at Koyama Astronomical Observatory

    NASA Astrophysics Data System (ADS)

    Kawakita, Hideyo; Shinnaka, Yoshiharu; Kondo, Sohei; Hamano, Satoshi; Sameshima, Hiroaki; Nakanishi, Kenshi; Kawanishi, Takafumi; Nakaoka, Tetsuya; Otsubo, Shogo; Kinoshita, Masaomi; Ikeda, Yuji; Yamamoto, Ryo; Izumi, Natsuko; Fukue, Kei; Yasui, Chikako; Mito, Hiroyuki; Sarugaku, Yuki; Matsunaga, Noriyuki; Kobayashi, Naoto

    2015-11-01

    CN radical has the strong electronic transition moments in optical wavelength region and CN has extensively observed in comets. Especially, the CN violet system (B2Σ+—X2Σ+) has been observed by using high-resolution spectroscopic technique in order to infer the isotopic ratios of carbon and nitrogen in comets via 12C14N, 13C14N and 12C15N. However, the wavelength range for this system (~388 nm) is severely extinct if a comet is close to the Sun (we have to observe the comet at low elevations from the ground-based observatories). On the other hand, CN radical also has the strong electronic transition in near-infrared (~1.1 microns), the CN red system (A2Πi—X2Σ+). Although there are few reports on the high-resolution spectra of this band in comets, this wavelength region is not severely affected by the telluric extinction and considered as the new window for the observations of the carbon and nitrogen isotopic ratios in comets.High resolution near-infrared spectra of comet C/2013 R1 (Lovejoy) using the WINERED (R~3x104) spectrometer mounted on the 1.3-m Araki telescope at Koyama Astronomical Observatory were acquired on UT 2013 Nov 30. The heliocentric and geocentric distances were 0.91 AU and 0.49 AU, respectively. We detected strong emission lines of the CN red system (0,0) at around 1.1 microns. The rotational line intensities of this band approximately follow the Boltzmann distribution at ~300K for our observations. We present the detailed analysis of the CN red system in comet C/2013 R1 (Lovejoy) and discuss about the isotopic ratios in CN.This research program is supported by the MEXT --- Supported Program for the Strategic Research Foundation at Private Universities, 2014 - 2018 and partially supported by JSPS, 15J10864.

  13. Many-body Tunneling and Nonequilibrium Dynamics of Doublons in Strongly Correlated Quantum Dots.

    PubMed

    Hou, WenJie; Wang, YuanDong; Wei, JianHua; Zhu, ZhenGang; Yan, YiJing

    2017-05-30

    Quantum tunneling dominates coherent transport at low temperatures in many systems of great interest. In this work we report a many-body tunneling (MBT), by nonperturbatively solving the Anderson multi-impurity model, and identify it a fundamental tunneling process on top of the well-acknowledged sequential tunneling and cotunneling. We show that the MBT involves the dynamics of doublons in strongly correlated systems. Proportional to the numbers of dynamical doublons, the MBT can dominate the off-resonant transport in the strongly correlated regime. A T 3/2 -dependence of the MBT current on temperature is uncovered and can be identified as a fingerprint of the MBT in experiments. We also prove that the MBT can support the coherent long-range tunneling of doublons, which is well consistent with recent experiments on ultracold atoms. As a fundamental physical process, the MBT is expected to play important roles in general quantum systems.

  14. Online Embryology teaching using learning management systems appears to be a successful additional learning tool among Egyptian medical students.

    PubMed

    Al-Neklawy, Ahmed Farid

    2017-11-01

    Although the traditional didactic lecture is considered to be efficient for presenting information and providing explanations, it usually does not provide adequate time for deeper learning activities. So, traditional lecture is one of the most widely criticized educational methods. Virtual learning environment (VLE) is a specially designed environment that facilitates teachers' management of educational courses for their students, using computer hardware and software, which involves distance learning. In this study, we evaluated the experiment of online teaching of General Embryology for Egyptian undergraduate medical students using WizIQ learning management system. A total of 100 students were invited to submit an online survey at the end of the course to evaluate delivery of instruction, creation of an environment that supported learning, and administrative issues. Most of the students reported that they were strongly satisfied with the efficacy of the instructional methods and were strongly satisfied with the degree of clarity of the course material. They strongly accepted the page format and design of the virtual classroom and strongly agreed that the learning environment supported the learning procedure. The item of easy logging into the virtual classroom had aberrant variable responses; it recorded the lowest mean response; this variation in responses was due to technical factors as the students used different devices with different speeds of internet connections. Ninety percent of students have strongly recommended the course attendance for their fellow students. These results demonstrate that online Anatomy teaching using learning management systems appears to be a successful additional learning tool among Egyptian medical students. Copyright © 2017 Elsevier GmbH. All rights reserved.

  15. An Ada implementation of the network manager for the advanced information processing system

    NASA Technical Reports Server (NTRS)

    Nagle, Gail A.

    1986-01-01

    From an implementation standpoint, the Ada language provided many features which facilitated the data and procedure abstraction process. The language supported a design which was dynamically flexible (despite strong typing), modular, and self-documenting. Adequate training of programmers requires access to an efficient compiler which supports full Ada. When the performance issues for real time processing are finally addressed by more stringent requirements for tasking features and the development of efficient run-time environments for embedded systems, the full power of the language will be realized.

  16. Programming model for distributed intelligent systems

    NASA Technical Reports Server (NTRS)

    Sztipanovits, J.; Biegl, C.; Karsai, G.; Bogunovic, N.; Purves, B.; Williams, R.; Christiansen, T.

    1988-01-01

    A programming model and architecture which was developed for the design and implementation of complex, heterogeneous measurement and control systems is described. The Multigraph Architecture integrates artificial intelligence techniques with conventional software technologies, offers a unified framework for distributed and shared memory based parallel computational models and supports multiple programming paradigms. The system can be implemented on different hardware architectures and can be adapted to strongly different applications.

  17. Research on a simulation-based ship production support system for middle-sized shipbuilding companies

    NASA Astrophysics Data System (ADS)

    Song, Young Joo; Woo, Jong Hun; Shin, Jong Gye

    2009-12-01

    Today, many middle-sized shipbuilding companies in Korea are experiencing strong competition from shipbuilding companies in other nations. This competition is particularly affecting small- and middle-sized shipyards, rather than the major shipyards that have their own support systems and development capabilities. The acquisition of techniques that would enable maximization of production efficiency and minimization of the gap between planning and execution would increase the competitiveness of small- and middle-sized Korean shipyards. In this paper, research on a simulation-based support system for ship production management, which can be applied to the shipbuilding processes of middle-sized shipbuilding companies, is presented. The simulation research includes layout optimization, load balancing, work stage operation planning, block logistics, and integrated material management. Each item is integrated into a network system with a value chain that includes all shipbuilding processes.

  18. Dynamic testing for shuttle design verification

    NASA Technical Reports Server (NTRS)

    Green, C. E.; Leadbetter, S. A.; Rheinfurth, M. H.

    1972-01-01

    Space shuttle design verification requires dynamic data from full scale structural component and assembly tests. Wind tunnel and other scaled model tests are also required early in the development program to support the analytical models used in design verification. Presented is a design philosophy based on mathematical modeling of the structural system strongly supported by a comprehensive test program; some of the types of required tests are outlined.

  19. Ideal gas behavior of a strongly coupled complex (dusty) plasma.

    PubMed

    Oxtoby, Neil P; Griffith, Elias J; Durniak, Céline; Ralph, Jason F; Samsonov, Dmitry

    2013-07-05

    In a laboratory, a two-dimensional complex (dusty) plasma consists of a low-density ionized gas containing a confined suspension of Yukawa-coupled plastic microspheres. For an initial crystal-like form, we report ideal gas behavior in this strongly coupled system during shock-wave experiments. This evidence supports the use of the ideal gas law as the equation of state for soft crystals such as those formed by dusty plasmas.

  20. Social organization of self-management support of persons with diabetes: a health systems comparison.

    PubMed

    Schiøtz, Michaela; Frølich, Anne; Krasnik, Allan; Taylor, Warren; Hsu, John

    2012-09-01

    Identify important organizational elements for providing self-management support (SMS). Semi-structured qualitative interviews conducted in two healthcare systems. Kaiser Permanente Northern California and the Danish Health Care System. 36 managers and healthcare professionals in the two healthcare systems. Elements important to providing self-management support to persons with diabetes. Healthcare professionals' provision of SMS was influenced by healthcare system organization and their perceptions of SMS, the capability and responsibility of healthcare systems, and their roles in the healthcare organization. Enabling factors for providing SMS included: strong leadership; aligned incentives; use of an integrated health information technology (HIT) system; multidisciplinary healthcare provider teams; ongoing training for healthcare professionals; outreach; and quality goals. Barriers to providing SMS included lack of collaboration between providers and skeptical attitudes towards prevention and outreach. Implementation of SMS can be improved by an understanding of the elements that enhance its provision: (1) initiatives seeking to improve collaboration and integration between providers; (2) implementation of an integrated HIT system; and (3) ongoing training of healthcare professionals.

  1. System Support for Forensic Inference

    NASA Astrophysics Data System (ADS)

    Gehani, Ashish; Kirchner, Florent; Shankar, Natarajan

    Digital evidence is playing an increasingly important role in prosecuting crimes. The reasons are manifold: financially lucrative targets are now connected online, systems are so complex that vulnerabilities abound and strong digital identities are being adopted, making audit trails more useful. If the discoveries of forensic analysts are to hold up to scrutiny in court, they must meet the standard for scientific evidence. Software systems are currently developed without consideration of this fact. This paper argues for the development of a formal framework for constructing “digital artifacts” that can serve as proxies for physical evidence; a system so imbued would facilitate sound digital forensic inference. A case study involving a filesystem augmentation that provides transparent support for forensic inference is described.

  2. Space station needs, attributes and architectural options. Volume 4, task 2 and 3: Mission implementation and cost

    NASA Technical Reports Server (NTRS)

    1983-01-01

    An overview of the basic space station infrastructure is presented. A strong case is made for the evolution of the station using the basic Space Transportation System (STS) to achieve a smooth transition and cost effective implementation. The integrated logistics support (ILS) element of the overall station infrastructure is investigated. The need for an orbital transport system capability that is the key to servicing and spacecraft positioning scenarios and associated mission needs is examined. Communication is also an extremely important element and the basic issue of station autonomy versus ground support effects the system and subsystem architecture.

  3. Addressing the Tension Between Strong Perimeter Control an Usability

    NASA Technical Reports Server (NTRS)

    Hinke, Thomas H.; Kolano, Paul Z.; Keller, Chris

    2006-01-01

    This paper describes a strong perimeter control system for a general purpose processing system, with the perimeter control system taking significant steps to address usability issues, thus mitigating the tension between strong perimeter protection and usability. A secure front end enforces two-factor authentication for all interactive access to an enclave that contains a large supercomputer and various associated systems, with each requiring their own authentication. Usability is addressed through a design in which the user has to perform two-factor authentication at the secure front end in order to gain access to the enclave, while an agent transparently performs public key authentication as needed to authenticate to specific systems within the enclave. The paper then describes a proxy system that allows users to transfer files into the enclave under script control, when the user is not present to perform two-factor authentication. This uses a pre-authorization approach based on public key technology, which is still strongly tied to both two-factor authentication and strict control over where files can be transferred on the target system. Finally the paper describes an approach to support network applications and systems such as grids or parallel file transfer protocols that require the use of many ports through the perimeter. The paper describes a least privilege approach that dynamically opens ports on a host-specific, if-authorized, as-needed, just-in-time basis.

  4. Role of initial coherence in the generation of harmonics and sidebands from a strongly driven two-level atom

    NASA Astrophysics Data System (ADS)

    Gauthey, F. I.; Keitel, C. H.; Knight, P. L.; Maquet, A.

    1995-07-01

    We investigate the coherent and incoherent contributions of the scattering spectrum of strongly driven two-level atoms as a function of the initial preparation of the atomic system. The initial ``phasing'' of the coherent superposition of the excited and ground states is shown to influence strongly the generation of both harmonics and hyper-Raman lines. In particular, we point out conditions under which harmonic generation can be inhibited at the expense of the hyper-Raman lines. Our numerical findings are supported by approximate analytical evaluation in the dressed state picture.

  5. Multi-client quantum key distribution using wavelength division multiplexing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Grice, Warren P; Bennink, Ryan S; Earl, Dennis Duncan

    Quantum Key Distribution (QKD) exploits the rules of quantum mechanics to generate and securely distribute a random sequence of bits to two spatially separated clients. Typically a QKD system can support only a single pair of clients at a time, and so a separate quantum link is required for every pair of users. We overcome this limitation with the design and characterization of a multi-client entangled-photon QKD system with the capacity for up to 100 clients simultaneously. The time-bin entangled QKD system includes a broadband down-conversion source with two unique features that enable the multi-user capability. First, the photons aremore » emitted across a very large portion of the telecom spectrum. Second, and more importantly, the photons are strongly correlated in their energy degree of freedom. Using standard wavelength division multiplexing (WDM) hardware, the photons can be routed to different parties on a quantum communication network, while the strong spectral correlations ensure that each client is linked only to the client receiving the conjugate wavelength. In this way, a single down-conversion source can support dozens of channels simultaneously--and to the extent that the WDM hardware can send different spectral channels to different clients, the system can support multiple client pairings. We will describe the design and characterization of the down-conversion source, as well as the client stations, which must be tunable across the emission spectrum.« less

  6. Pressurized Martian-Like Pure CO2 Atmosphere Supports Strong Growth of Cyanobacteria, and Causes Significant Changes in their Metabolism

    NASA Astrophysics Data System (ADS)

    Murukesan, Gayathri; Leino, Hannu; Mäenpää, Pirkko; Ståhle, Kurt; Raksajit, Wuttinun; Lehto, Harry J.; Allahverdiyeva-Rinne, Yagut; Lehto, Kirsi

    2016-03-01

    Surviving of crews during future missions to Mars will depend on reliable and adequate supplies of essential life support materials, i.e. oxygen, food, clean water, and fuel. The most economical and sustainable (and in long term, the only viable) way to provide these supplies on Martian bases is via bio-regenerative systems, by using local resources to drive oxygenic photosynthesis. Selected cyanobacteria, grown in adequately protective containment could serve as pioneer species to produce life sustaining substrates for higher organisms. The very high (95.3 %) CO2 content in Martian atmosphere would provide an abundant carbon source for photo-assimilation, but nitrogen would be a strongly limiting substrate for bio-assimilation in this environment, and would need to be supplemented by nitrogen fertilizing. The very high supply of carbon, with rate-limiting supply of nitrogen strongly affects the growth and the metabolic pathways of the photosynthetic organisms. Here we show that modified, Martian-like atmospheric composition (nearly 100 % CO2) under various low pressure conditions (starting from 50 mbar to maintain liquid water, up to 200 mbars) supports strong cellular growth. Under high CO2 / low N2 ratio the filamentous cyanobacteria produce significant amount of H2 during light due to differentiation of high amount of heterocysts.

  7. Environmental control and life support - Partially closed system will save big money

    NASA Technical Reports Server (NTRS)

    Guy, W. W.

    1983-01-01

    Although the NASA space station has not yet been completely defined, realistic estimates may be made of the environmental control and life support system requirements entailed by a crew of eight, a resupply interval of 90 days, an initial launch which includes expendables for the first resupply interval, 7.86 lb/day of water per person, etc. An appraisal of these requirements is presented which strongly suggests the utility of a partially closed life support system. Such a scheme would give the crew high quality water to drink, and recycle nonpotable water from hand washing, bathing, clothes and dish washing, and urinal flushing. The excess recovery process water is electrolyzed to provide metabolic and leakage oxygen. The crew would drink electrolysis water and atmospheric humidity control moisture-derived water.

  8. Intial orbit determination results for Jason-1: towards a 1-cm orbit

    NASA Technical Reports Server (NTRS)

    Haines, B. J.; Haines, B.; Bertiger, W.; Desai, S.; Kuang, D.; Munson, T.; Reichert, A.; Young, L.; Willis, P.

    2002-01-01

    The U.S/France Jason-1 oceanographic mission is carrying state-of-the-art radiometric tracking systems (GPS and Doris) to support precise orbit determination (POD) requirements. The performance of the systems is strongly reflected in the early POD results. Results of both internal and external (e.g., satellite laser ranging) comparisons support that the 2.5 cm radial Rh4S requirement is being readily met, and provide reasons for optimism that 1 cm can be achieved. We discuss the POD strategy underlying these orbits, as well as the challenging issues that bear on the understanding and characterization of an orbit solution at the l-cm level. We also describe a system for producing science quality orbits in near real time in order to support emerging applications in operational oceanography.

  9. NASA presentation. [wind energy conversion systems planning

    NASA Technical Reports Server (NTRS)

    Thomas, R. L.

    1973-01-01

    The development of a wind energy system is outlined that supplies reliable energy at a cost competitive with other energy systems. A government directed industry program with strong university support is recommended that includes meteorological studies to estimate wind energy potentials and determines favorable regions and sites for wind power installations. Key phases of the overall program are wind energy conversion systems, meteorological wind studies, energy storage systems, and environmental impact studies. Performance testing with a prototype wind energy conversion and storage system is projected for Fiscal 1977.

  10. Reactivity of Transition Metals (Pd Pt Cu Ag Au) toward Molecular Hydrogen Dissociation: Extended Surfaces versus Particles Supported on TiC(001) or Small Is Not Always Better and Large Is Not Always Bad

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rodriguez J. A.; Gomez T.; Florez E.

    2011-06-16

    The reactivity of Pd{sub 4}, Pt{sub 4}, Cu{sub 4}, Ag{sub 4}, and Au{sub 4} clusters supported on TiC(001) toward molecular hydrogen dissociation has been studied by means of density functional based theory and periodic models and compared to that of the (111) and (001) surfaces. Pd{sub 4} and Pt{sub 4} interact rather strongly with the TiC(001) substrate, but the interaction of molecular hydrogen with the Pd{sub 4}/TiC and Pt{sub 4}/TiC systems is also very strong. As a consequence of the substantial admetal {leftrightarrow} carbide interactions, the adsorbed H{sub 2} molecule becomes more difficult to dissociate than on the corresponding extendedmore » (111) and (001) surfaces. Here, having a small supported particle does not lead to an enhanced chemical activity. On the contrary, for the Cu{sub 4}/TiC, Ag{sub 4}/TiC, and Au{sub 4}/TiC systems the combination of the small size of the particle and the polarization induced by the underlying carbide facilitates the dissociation of the hydrogen molecule with respect to the case of the extended surfaces. Here, the reduced size effectively enhances the activity of the supported particle. Thus, our results for the M(111), M(100), and M{sub 4}/TiC(001) systems show the complex interplay that can take place among the nature of the admetal, particle size effects, and support interactions.« less

  11. Reactivity of Transition Metals (Pd, Pt, Cu, Ag, Au) toward Molecular Hydrogen Dissociation: Extended Surfaces versus Particles Supported on TiC(001) or Small Is Not Always Better and Large Is Not Always Bad

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rodriguez, J.A.; Gomez, T.; Florez, E.

    2011-05-11

    The reactivity of Pd{sub 4}, Pt{sub 4}, Cu{sub 4}, Ag{sub 4}, and Au{sub 4} clusters supported on TiC(001) toward molecular hydrogen dissociation has been studied by means of density functional based theory and periodic models and compared to that of the (111) and (001) surfaces. Pd{sub 4} and Pt{sub 4} interact rather strongly with the TiC(001) substrate, but the interaction of molecular hydrogen with the Pd{sub 4}/TiC and Pt{sub 4}/TiC systems is also very strong. As a consequence of the substantial admetal {leftrightarrow} carbide interactions, the adsorbed H{sub 2} molecule becomes more difficult to dissociate than on the corresponding extendedmore » (111) and (001) surfaces. Here, having a small supported particle does not lead to an enhanced chemical activity. On the contrary, for the Cu{sub 4}/TiC, Ag{sub 4}/TiC, and Au{sub 4}/TiC systems the combination of the small size of the particle and the polarization induced by the underlying carbide facilitates the dissociation of the hydrogen molecule with respect to the case of the extended surfaces. Here, the reduced size effectively enhances the activity of the supported particle. Thus, our results for the M(111), M(100), and M{sub 4}/TiC(001) systems show the complex interplay that can take place among the nature of the admetal, particle size effects, and support interactions.« less

  12. Clinical decision support provided within physician order entry systems: a systematic review of features effective for changing clinician behavior.

    PubMed

    Kawamoto, Kensaku; Lobach, David F

    2003-01-01

    Computerized physician order entry (CPOE) systems represent an important tool for providing clinical decision support. In undertaking this systematic review, our objective was to identify the features of CPOE-based clinical decision support systems (CDSSs) most effective at modifying clinician behavior. For this review, two independent reviewers systematically identified randomized controlled trials that evaluated the effectiveness of CPOE-based CDSSs in changing clinician behavior. Furthermore, each included study was assessed for the presence of 14 CDSS features. We screened 10,023 citations and included 11 studies. Of the 10 studies comparing a CPOE-based CDSS intervention against a non-CDSS control group, 7 reported a significant desired change in professional practice. Moreover, meta-regression analysis revealed that automatic provision of the decision support was strongly associated with improved professional practice (adjusted odds ratio, 23.72; 95% confidence interval, 1.75-infiniti). Thus, we conclude that automatic provision of decision support is a critical feature of successful CPOE-based CDSS interventions.

  13. [Facts visualized through job support activities for mentally disordered persons--what is the objective of medical treatment for mental disorder?].

    PubMed

    Tagawa, Seiji

    2014-01-01

    According to a recent investigation by the Public Employment Security Office, the rate of employing mentally disordered persons is increasing. In the report, it was predicted that the number of employed mentally disordered persons will exceed the number of physically disordered persons within a few years, and will become the highest of the main three disabled types. Despite the strong desire of mentally disordered persons to work, supporting systems have been inadequate. In 2007, mental clinic doctors in Osaka took the lead and established the NPO Osaka Job Support Network for Mentally Disordered Persons (JSN) to support their employment persons. We aimed to establish a support system for mentally disordered persons who have a strong will to work, stating "I would like to work" to their family doctors, who introduce JSN to the patients, and then the family doctors and JSN cooperate to support the patients to realize the desire to "work". Since April 2013, 49 persons have found a job and "graduated" from JSN. Over 6 years until the end of March, 2013, a total of 154 persons found jobs and "graduated" from JSN. From now on, it is expected that around 50 persons will find jobs and "graduate" from JSN every year. It is definitely insufficient just to repeat "temporary" medical treatment for mental disorders with a long course like schizophrenia. A care management view that values the hopes and dreams of patients is required in psychiatric treatment.

  14. Learning from the implementation of inter-organisational web-based care planning and coordination.

    PubMed

    Walker, Rae; Blacker, Vivian; Pandita, Linda; Close, Jacky; Mason, Wendy; Watson, Julie

    2013-01-01

    In Victoria, despite strong policy support, e-care planning and coordination is poorly developed. The action research project discussed here was developed to overcome organisational and worker-level barriers to change. The project outcomes highlighted the need for work on the building blocks of e-care coordination that enhance workers' knowledge and skills, and provide permission and support for appropriate collaborative system and services coordination practices.

  15. Preserved Entropy, quantum criticality and fragile magnetism

    NASA Astrophysics Data System (ADS)

    Canfield, Paul

    A large swath of strongly correlated electron systems can be associated with the phenomenon of preserved entropy and fragile magnetism. In this talk I will present our thoughts and plans for the discovery and development of lanthanide and transition metal based, strongly correlated systems that are revealed by suppressed, fragile magnetism or grow out of preserved entropy. This talk is based on work published in This work was supported by the U.S. Dept. of Energy, Basic Energy Science, Division of Materials Sciences and Engineering under Contract No. DE-AC02-07CH11358 as well as by the Gordon and Betty Moore Foundations EPiQS Initiative through Grant GBMF4411.

  16. Redox processes at a nanostructured interface under strong electric fields.

    PubMed

    Steurer, Wolfram; Surnev, Svetlozar; Netzer, Falko P; Sementa, Luca; Negreiros, Fabio R; Barcaro, Giovanni; Durante, Nicola; Fortunelli, Alessandro

    2014-09-21

    Manipulation of chemistry and film growth via external electric fields is a longstanding goal in surface science. Numerous systems have been predicted to show such effects but experimental evidence is sparse. Here we demonstrate in a custom-designed UHV apparatus that the application of spatially extended, homogeneous, very high (>1 V nm(-1)) DC-fields not only changes the system energetics but triggers dynamic processes which become important much before static contributions appreciably modify the potential energy landscape. We take a well characterized ultrathin NiO film on a Ag(100) support as a proof-of-principle test case, and show how it gets reduced to supported Ni clusters under fields exceeding the threshold of +0.9 V nm(-1). Using an effective model, we trace the observed interfacial redox process down to a dissociative electron attachment resonant mechanism. The proposed approach can be easily implemented and generally applied to a wide range of interfacial systems, thus opening new opportunities for the manipulation of film growth and reaction processes at solid surfaces under strong external fields.

  17. The Appropriateness of Entrepreneurial Training in Wisconsin's Employment and Training System. Employment and Training Policy Paper No. 3.

    ERIC Educational Resources Information Center

    Carstensen, Carol

    Small businesses play a strong role in generating new jobs. Policymakers have been encouraged to find ways to foster and support their development, especially by linking entrepreneurial training to the existing employment and training system. The purpose of this paper is to provide a background and a focus for further discussion of entrepreneurial…

  18. How research is fueling the RAS boom

    USDA-ARS?s Scientific Manuscript database

    The Conservation Fund’s Freshwater Institute has been researching water recirculating aquaculture system (RAS) technologies and practices for salmonids for nearly 30 years using strong funding support from the U.S. Department of Agriculture’s Agricultural Research Service. These early efforts to pio...

  19. Processing and review interface for strong motion data (PRISM) software, version 1.0.0—Methodology and automated processing

    USGS Publications Warehouse

    Jones, Jeanne; Kalkan, Erol; Stephens, Christopher

    2017-02-23

    A continually increasing number of high-quality digital strong-motion records from stations of the National Strong-Motion Project (NSMP) of the U.S. Geological Survey (USGS), as well as data from regional seismic networks within the United States, call for automated processing of strong-motion records with human review limited to selected significant or flagged records. The NSMP has developed the Processing and Review Interface for Strong Motion data (PRISM) software to meet this need. In combination with the Advanced National Seismic System Quake Monitoring System (AQMS), PRISM automates the processing of strong-motion records. When used without AQMS, PRISM provides batch-processing capabilities. The PRISM version 1.0.0 is platform independent (coded in Java), open source, and does not depend on any closed-source or proprietary software. The software consists of two major components: a record processing engine and a review tool that has a graphical user interface (GUI) to manually review, edit, and process records. To facilitate use by non-NSMP earthquake engineers and scientists, PRISM (both its processing engine and review tool) is easy to install and run as a stand-alone system on common operating systems such as Linux, OS X, and Windows. PRISM was designed to be flexible and extensible in order to accommodate new processing techniques. This report provides a thorough description and examples of the record processing features supported by PRISM. All the computing features of PRISM have been thoroughly tested.

  20. The Effects of Geographic Isolation and Social Support on the Health of Wisconsin Women.

    PubMed

    Tittman, Sarah M; Harteau, Christy; Beyer, Kirsten M M

    2016-04-01

    Rural residents are less likely to receive preventive health screening, more likely to be uninsured, and more likely to report fair to poor health than urban residents. Social disconnectedness and perceived isolation are known to be negative predictors of self-rated physical health; however, the direct effects of geographic isolation and social support on overall health have not been well elucidated. A cross-sectional survey of women (n = 113) participating in Wisconsin Rural Women's initiative programming was conducted, which included measures of geographic isolation, an assessment of overall health, and social support using the validated Interpersonal Support Evaluation List with 3 subscales, including belonging support, tangible support, and appraisal support. Geographic isolation was shown to be a negative predictor of belonging support (P = .0064) and tangible support (P = .0349); however, geographic isolation was not a statistically significant predictor of appraisal support. A strong and direct relationship was observed between social support and self-perceived health status among this population of Wisconsin women, and hospital access based on geographic proximity was positively correlated (P = .028) with overall health status. The direct relationship between social support and overall health demonstrated here stresses the importance of developing and maintaining strong social support networks, which can be improved through rural support groups that have the unique ability to assist rural residents in fostering social support systems, advocating stress management techniques, and achieving a greater sense of well-being.

  1. Inductrack III configuration--a maglev system for high loads

    DOEpatents

    Post, Richard F

    2015-03-24

    Inductrack III configurations are suited for use in transporting heavy freight loads. Inductrack III addresses a problem associated with the cantilevered track of the Inductrack II configuration. The use of a cantilevered track could present mechanical design problems in attempting to achieve a strong enough track system such that it would be capable of supporting very heavy loads. In Inductrack III, the levitating portion of the track can be supported uniformly from below, as the levitating Halbach array used on the moving vehicle is a single-sided one, thus does not require the cantilevered track as employed in Inductrack II.

  2. Inductrack III configuration--a maglev system for high loads

    DOEpatents

    Post, Richard F

    2013-11-12

    Inductrack III configurations are suited for use in transporting heavy freight loads. Inductrack III addresses a problem associated with the cantilevered track of the Inductrack II configuration. The use of a cantilevered track could present mechanical design problems in attempting to achieve a strong enough track system such that it would be capable of supporting very heavy loads. In Inductrack III, the levitating portion of the track can be supported uniformly from below, as the levitating Halbach array used on the moving vehicle is a single-sided one, thus does not require the cantilevered track as employed in Inductrack II.

  3. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Plessow, Philipp N.; Bajdich, Michal; Greene, Joshua

    The formation of thin oxide films on metal supports is an important phenomenon, especially in the context of strong metal support interaction (SMSI). Computational predictions of the stability of these films are hampered by their structural complexity and a varying lattice mismatch with different supports. In this study, we report a large combination of supports and ultrathin oxide films studied with density functional theory (DFT). Trends in stability are investigated through a descriptor-based analysis. Since the studied films are bound to the support exclusively through metal–metal interaction, the adsorption energy of the oxide-constituting metal atom can be expected to bemore » a reasonable descriptor for the stability of the overlayers. If the same supercell is used for all supports, the overlayers experience different amounts of stress. Using supercells with small lattice mismatch for each system leads to significantly improved scaling relations for the stability of the overlayers. Finally, this approach works well for the studied systems and therefore allows the descriptor-based exploration of the thermodynamic stability of supported thin oxide layers.« less

  4. Public support for social financing of health care in Switzerland.

    PubMed

    Perneger, Thomas V; Hudelson, Patricia M

    2005-01-01

    The purpose of this study was to identify factors associated with the public's preference for financing health care according to people's ability to pay. The authors compared voters' support in 26 Swiss cantons for a legislative proposal to replace regionally rated health insurance premiums (current system) with premiums proportional to income and wealth, and co-financed through the value added tax. The vote took place in May 2003, and the initiative was rejected, with only 27 percent of support nationwide. However, support varied more than threefold, from 13 to 44 percent, among cantons. In multivariate analysis, support was most strongly correlated with the approval rate of the 1994 law on health insurance, which strengthened solidarity between the sick and the healthy. More modest associations were seen between support for the initiative and the health insurance premium of 2003, and proportions of elderly and urban residents in the population. Hence support for more social financing of health care was best explained by past preference for a social health insurance system in the local community.

  5. The connection between strong social support and joint replacement outcomes.

    PubMed

    Theiss, Mark M; Ellison, Michael W; Tea, Christine G; Warner, Julia F; Silver, Renee M; Murphy, Valerie J

    2011-05-18

    A myriad of emotional, informational, and tangible needs can easily overwhelm patients as they seek to navigate a complicated surgical procedure. This article demonstrates that a dedicated family member or friend supporting their loved one before, during, and after joint replacement surgery measurably impacts quality and outcomes. The multidisciplinary, multihospital study team developed the following Opportunity Statement: "To define, measure, and implement a progressive family/friend support system across the continuum of care promoting optimal patient recovery after total joint arthroplasty." The team used the modified Groningen Orthopedic Social Support Scale to measure levels of social support and associated these levels with other patient outcomes.Analysis of 1722 observations across 4 hospitals found that patients with strong social support have shorter hospital stays, are more likely to be discharged home, to meet ambulation and transfer-out-of-bed targets, and to score hospital quality of care higher, and are more confident and ready to go home on discharge. Three presence intervals were also found to be significant predictors of key outcome measures: family/friend presence during the preoperative classes, in the preoperative holding area, and during the last physical therapy session. These intervals may serve as reasonable social support proxies for organizations desiring to measure social support to ultimately affect quality and outcomes. Copyright 2011, SLACK Incorporated.

  6. Functional architecture and global properties of the Corynebacterium glutamicum regulatory network: Novel insights from a dataset with a high genomic coverage.

    PubMed

    Freyre-González, Julio A; Tauch, Andreas

    2017-09-10

    Corynebacterium glutamicum is a Gram-positive, anaerobic, rod-shaped soil bacterium able to grow on a diversity of carbon sources like sugars and organic acids. It is a biotechnological relevant organism because of its highly efficient ability to biosynthesize amino acids, such as l-glutamic acid and l-lysine. Here, we reconstructed the most complete C. glutamicum regulatory network to date and comprehensively analyzed its global organizational properties, systems-level features and functional architecture. Our analyses show the tremendous power of Abasy Atlas to study the functional organization of regulatory networks. We created two models of the C. glutamicum regulatory network: all-evidences (containing both weak and strong supported interactions, genomic coverage=73%) and strongly-supported (only accounting for strongly supported evidences, genomic coverage=71%). Using state-of-the-art methodologies, we prove that power-law behaviors truly govern the connectivity and clustering coefficient distributions. We found a non-previously reported circuit motif that we named complex feed-forward motif. We highlighted the importance of feedback loops for the functional architecture, beyond whether they are statistically over-represented or not in the network. We show that the previously reported top-down approach is inadequate to infer the hierarchy governing a regulatory network because feedback bridges different hierarchical layers, and the top-down approach disregards the presence of intermodular genes shaping the integration layer. Our findings all together further support a diamond-shaped, three-layered hierarchy exhibiting some feedback between processing and coordination layers, which is shaped by four classes of systems-level elements: global regulators, locally autonomous modules, basal machinery and intermodular genes. Copyright © 2016 Elsevier B.V. All rights reserved.

  7. Confinement of active systems: trapping, swim pressure, and explosions

    NASA Astrophysics Data System (ADS)

    Takatori, Sho; de Dier, Raf; Vermant, Jan; Brady, John

    2015-11-01

    We analyze the run-and-tumble dynamics and motion of living bacteria and self-propelled Janus motors confined in an acoustic trap. Since standard optical tweezers are far too weak, we developed an acoustic trap strong enough to confine swimmers over distances large compared to the swimmers' size and run length. The external trap behaves as an ``osmotic barrier'' that confines the swimmers inside the trapping region, analogous to semipermeable membranes that confine passive Brownian particles inside a boundary. From the swimmers' restricted motion inside the trap, we calculate the unique swim pressure generated by active systems originating from the force required to confine them by boundaries. We apply a strong trap to collect the swimmers into a close-packed active crystal and then turn off the trap which causes the crystal to ``explode'' due to an imbalance of the active pressure. We corroborate all experimental results with Brownian dynamics simulations and analytical theory. ST is supported by a Gates Millennium Scholars fellowship and a NSF Fellowship No. DGE-1144469. RDD is supported by a doctoral fellowship of the fund for scientific research (FWO-Vlaanderen). This work is also supported by NSF Grant CBET 1437570.

  8. Tony Magri | NREL

    Science.gov Websites

    Windows System Engineer with the Computational Science Center. He implements, supports, and integrates Windows-based technology solutions at the ESIF and manages a portion of the VMware infrastructure . Throughout his career, Tony has built a strong skillset in enterprise Windows Engineering and Active

  9. Design Considerations for Abrasive Blast Rooms and Recovery Systems

    DTIC Science & Technology

    2010-02-01

    COLUMN BOLT – ALLOWS FOR WIDER ENCLOSURES – STRONG ENOUGH TO SUPPORT MONORAIL Flange Bolt Room Column Bolt Room • Structural steel framework...OVERHEAD MONORAILS • EXTERIOR WORK STATIONS • TURNTABLES • HORIZONTAL ROTATION DEVICES OVERHEAD MONORAIL Workpiece Handling • Powered horizontal rotation

  10. Modeling Mars Cyclogenesis and Frontal Waves: Seasonal Variations and Implications on Dust Activity

    NASA Technical Reports Server (NTRS)

    Hollingsworth, J. L.; Kahre, M. A.

    2014-01-01

    Between late autumn through early spring,middle and high latitudes onMars exhibit strong equator-to-polemean temperature contrasts (i.e., "baroclinicity"). Data collected during the Viking era and observations from both the Mars Global Surveyor (MGS) and Mars Reconnaissance Orbiter (MRO) indicate that such strong baroclinicity supports vigorous, large-scale eastward traveling weather systems (i.e., transient synoptic period waves) [1, 2]. For a rapidly rotating, differentially heated, shallow atmosphere such as on Earth and Mars, these large-scale, extratropical weather disturbances are critical components of the global circulation. The wave-like disturbances serve as agents in the transport of heat and momentum between low and high latitudes of the planet. Through cyclonic/anticyclonic winds, intense shear deformations, contractions-dilatations in temperature and density, and sharp perturbations amongst atmospheric tracers (i.e., dust, volatiles (e.g., water vapor) and condensates (e.g., water-ice cloud particles)), Mars' extratropical weather systems have significant sub-synoptic scale ramifications by supporting atmospheric frontal waves (Fig. 1).

  11. Extratropical Cyclogenesis and Frontal Waves on Mars: Influences on Dust, Weather and the Planet's climate

    NASA Technical Reports Server (NTRS)

    Hollingsworth, J. L.; Kahre, Melinda A.

    2012-01-01

    Between late autumn and early spring, middle and high latitudes on Mars exhibit strong equatortopole mean temperature contrasts (i.e., "baroclinicity"). Data collected during the Viking era and observations from both the Mars Global Surveyor (MGS) and Mars Reconnaissance Orbiter (MRO) indicate that this strong baroclinicity supports vigorous, large-scale eastward traveling weather systems (i.e., transient synoptic periodwaves) [1,2]. For a rapidly rotating, differentially heated, shallow atmosphere such as on Earth and Mars, these large-scale, extratropical weather disturbances are critical components of the global circulation. The wavelike disturbances act as agents in the transport of heat and momentum between low and high latitudes of the planet. Through cyclonic/anticyclonic winds, intense shear deformations, contractions-dilatations in temperature and density, and sharp perturbations amongst atmospheric tracers (i.e., dust, volatiles (e.g., water vapor) and condensates (e.g., water-ice cloud particles)), Mars extratropical weather systems have significant subsynoptic scale ramifications by supporting atmospheric frontal waves (Fig. 1).

  12. Neighborhood graph and learning discriminative distance functions for clinical decision support.

    PubMed

    Tsymbal, Alexey; Zhou, Shaohua Kevin; Huber, Martin

    2009-01-01

    There are two essential reasons for the slow progress in the acceptance of clinical case retrieval and similarity search-based decision support systems; the especial complexity of clinical data making it difficult to define a meaningful and effective distance function on them and the lack of transparency and explanation ability in many existing clinical case retrieval decision support systems. In this paper, we try to address these two problems by introducing a novel technique for visualizing inter-patient similarity based on a node-link representation with neighborhood graphs and by considering two techniques for learning discriminative distance function that help to combine the power of strong "black box" learners with the transparency of case retrieval and nearest neighbor classification.

  13. Research Opportunities Supporting the Vision for Space Exploration from the Transformation of the Former Microgravity Materials Science Program

    NASA Technical Reports Server (NTRS)

    Clinton, R. G., Jr.; Szofran, Frank; Bassler, Julie A.; Schlagheck, Ronald A.; Cook, Mary Beth

    2005-01-01

    The Microgravity Materials Science Program established a strong research capability through partnerships between NASA and the scientific research community. With the announcement of the vision for space exploration, additional emphasis in strategic materials science areas was necessary. The President's Commission recognized that achieving its exploration objectives would require significant technical innovation, research, and development in focal areas defined as "enabling technologies." Among the 17 enabling technologies identified for initial focus were: advanced structures, advanced power and propulsion; closed-loop life support and habitability; extravehicular activity systems; autonomous systems and robotics; scientific data collection and analysis, biomedical risk mitigation; and planetary in situ resource utilization. Mission success may depend upon use of local resources to fabricate a replacement part to repair a critical system. Future propulsion systems will require materials with a wide range of mechanical, thermophysical, and thermochemical properties, many of them well beyond capabilities of today's materials systems. Materials challenges have also been identified by experts working to develop advanced life support systems. In responding to the vision for space exploration, the Microgravity Materials Science Program aggressively transformed its research portfolio and focused materials science areas of emphasis to include space radiation shielding; in situ fabrication and repair for life support systems; in situ resource utilization for life support consumables; and advanced materials for exploration, including materials science for space propulsion systems and for life support systems. The purpose of this paper is to inform the scientific community of these new research directions and opportunities to utilize their materials science expertise and capabilities to support the vision for space exploration.

  14. We strongly support childhood immunisation-statement from the European Academy of Paediatrics (EAP).

    PubMed

    Dornbusch, Hans Juergen; Hadjipanayis, Adamos; Del Torso, Stefano; Mercier, Jean-Christophe; Wyder, Corinne; Schrier, Lenneke; Ross-Russell, Robert; Stiris, Tom; Ludvigsson, Jonas F

    2017-05-01

    The eradication of smallpox and the elimination of several other infectious diseases from much of the world has provided convincing evidence that vaccines are among the most effective interventions for promoting health. The current scepticism about immunisation among members of the new US administration carries a risk of decreasing immunisation rates also in Europe. While only a small minority of the population are strongly anti-vaccine, their public activities have significantly influenced an uncertainty among the general population about both the safety of and the necessity for vaccination. Therefore, the EAP calls for greater publically available, scientifically supported information on vaccination, particularly targeted at health care providers, for the further development of electronically based immunisation information systems (IIS). We further call on all European countries to work together both in legislative and public health arenas in order to increase vaccination coverage among the paediatric population. In the interest of children and their parents, the EAP expresses its strong support for childhood immunisation and recommended vaccination schedules. We are prepared to work with governments and media and share the extensive evidence demonstrating the effectiveness and safety of vaccines.

  15. Exploring the nonequilibrium dynamics of ultracold quantum gases by using numerical tools

    NASA Astrophysics Data System (ADS)

    Heidrich-Meisner, Fabian

    Numerical tools such as exact diagonalization or the density matrix renormalization group method have been vital for the study of the nonequilibrium dynamics of strongly correlated many-body systems. Moreover, they provided unique insight for the interpretation of quantum gas experiments, whenever a direct comparison with theory is possible. By considering the example of the experiment by Ronzheimer et al., in which both an interaction quench and the release of bosons from a trap into an empty optical lattice (sudden expansion) was realized, I discuss several nonequilibrium effects of strongly interacting quantum gases. These include the thermalization of a closed quantum system and its connection to the eigenstate thermalization hypothesis, nonequilibrium mass transport, dynamical fermionization, and transient phenomena such as quantum distillation or dynamical quasicondensation. I highlight the role of integrability in giving rise to ballistic transport in strongly interacting 1D systems and in determining the asymptotic state after a quantum quench. The talk concludes with a perspective on open questions concerning 2D systems and the numerical simulation of their nonequilibrium dynamics. Supported by Deutsche Forschungsgemeinschaft (DFG) via FOR 801.

  16. Oxytocin Genotype Moderates the Impact of Social Support on Psychiatric Distress in Alcohol-Dependent Patients.

    PubMed

    Love, Tiffany M; Cranford, James A; Burmeister, Margit; Wojnar, Marcin; Zucker, Robert A; J Brower, Kirk

    2018-01-01

    The social environment strongly influences individual mental health. Individuals with strong social support systems tend to experience higher levels of well-being, lower levels of psychological distress and exhibit fewer psychiatric symptoms. However, there is a significant degree of individual variability as to the extent to which social support is beneficial to overall mental health. From a neurobiological perspective, it is suggested that the social hormone, oxytocin, may moderate the favorable effects of social interaction. To explore this possibility, we evaluated oxytocin genotype, social support and psychological health in a group of individuals diagnosed with DSM-IV alcohol dependence. The associations between OXT genotype, social support and psychological health were analyzed in data from 269 adults diagnosed with DSM-IV alcohol dependence (25% female) admitted into residential treatment programs and outpatient centers in Warsaw, Poland. In line with past observations, we noted that psychiatric distress scores were negatively correlated with social support. Extending these observations, we uncovered a significant moderating effect of OXT genotype (rs2740210) on the relationship between social support and psychiatric distress. While G carriers displayed the predicted negative relationship between social support and psychiatric distress, T homozygotes failed to exhibit such a relationship. Genetically driven variation in oxytocin system functioning may influence the degree to which the beneficial effects of social support are felt in this population. These results have direct clinical relevance as enhancing social engagement to improve mental health may prove to be a less effective strategy in some patients owing to intrinsic factors. The associations between oxytocin genotype, social support, and psychological health were analyzed in data from 269 adults diagnosed with DSM-IV alcohol dependence. A significant moderating effect of OXT genotype (rs2740210) on the relationship between social support and psychiatric distress was detected. © The Author 2017. Medical Council on Alcohol and Oxford University Press. All rights reserved.

  17. Creating and sharing clinical decision support content with Web 2.0: Issues and examples.

    PubMed

    Wright, Adam; Bates, David W; Middleton, Blackford; Hongsermeier, Tonya; Kashyap, Vipul; Thomas, Sean M; Sittig, Dean F

    2009-04-01

    Clinical decision support is a powerful tool for improving healthcare quality and patient safety. However, developing a comprehensive package of decision support interventions is costly and difficult. If used well, Web 2.0 methods may make it easier and less costly to develop decision support. Web 2.0 is characterized by online communities, open sharing, interactivity and collaboration. Although most previous attempts at sharing clinical decision support content have worked outside of the Web 2.0 framework, several initiatives are beginning to use Web 2.0 to share and collaborate on decision support content. We present case studies of three efforts: the Clinfowiki, a world-accessible wiki for developing decision support content; Partners Healthcare eRooms, web-based tools for developing decision support within a single organization; and Epic Systems Corporation's Community Library, a repository for sharing decision support content for customers of a single clinical system vendor. We evaluate the potential of Web 2.0 technologies to enable collaborative development and sharing of clinical decision support systems through the lens of three case studies; analyzing technical, legal and organizational issues for developers, consumers and organizers of clinical decision support content in Web 2.0. We believe the case for Web 2.0 as a tool for collaborating on clinical decision support content appears strong, particularly for collaborative content development within an organization.

  18. Computer Models Identify Methods to Reduce Bridge Cracks During Production Processes : Brief

    DOT National Transportation Integrated Search

    2012-06-01

    While most motorists see only the bridge deck, strong bridge girders are the basis for a stable system to support the traffic-handling surface. Concrete bridge girders often have two major components: the web, which is an I-shaped cross section and v...

  19. Pharmacological and structure-activity relationship evaluation of 4-aryl-1-diphenylacetyl(thio)semicarbazides.

    PubMed

    Wujec, Monika; Kędzierska, Ewa; Kuśmierz, Edyta; Plech, Tomasz; Wróbel, Andrzej; Paneth, Agata; Orzelska, Jolanta; Fidecka, Sylwia; Paneth, Piotr

    2014-04-16

    This article describes the synthesis of six 4-aryl-(thio)semicarbazides (series a and b) linked with diphenylacetyl moiety along with their pharmacological evaluation on the central nervous system in mice and computational studies, including conformational analysis and electrostatic properties. All thiosemicarbazides (series b) were found to exhibit strong antinociceptive activity in the behavioural model. Among them, compound 1-diphenylacetyl-4-(4-methylphenyl)thiosemicarbazide 1b was found to be the most potent analgesic agent, whose activity is connected with the opioid system. For compounds from series a significant anti-serotonergic effect, especially for compound 1-diphenylacetyl-4-(4-methoxyphenyl)semicarbazide 2b was observed. The computational studies strongly support the obtained results.

  20. HPC Annual Report: Emulytics.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Crussell, Jonathan; Boote, Jeffrey W.; Fritz, David Jakob

    Networked Information Technology systems play a key role supporting critical government, military, and private computer installations. Many of today's critical infrastructure systems have strong dependencies on secure information exchange among geographically dispersed facilities. As operations become increasingly dependent on the information exchange they also become targets for exploitation. The need to protect data and defend these systems from external attack has become increasingly vital while the nature of the threats has become sophisticated and pervasive making the challenges daunting. Enter Emulytics.

  1. Psychometric analysis of the leadership environment scale (LENS): Outcome from the Oregon research initiative on the organisation of nursing (ORION).

    PubMed

    Ross, Amy M; Ilic, Kelley; Kiyoshi-Teo, Hiroko; Lee, Christopher S

    2017-12-26

    The purpose of this study was to establish the psychometric properties of the new 16-item leadership environment scale. The leadership environment scale was based on complexity science concepts relevant to complex adaptive health care systems. A workforce survey of direct-care nurses was conducted (n = 1,443) in Oregon. Confirmatory factor analysis, exploratory factor analysis, concordant validity test and reliability tests were conducted to establish the structure and internal consistency of the leadership environment scale. Confirmatory factor analysis indices approached acceptable thresholds of fit with a single factor solution. Exploratory factor analysis showed improved fit with a two-factor model solution; the factors were labelled 'influencing relationships' and 'interdependent system supports'. Moderate to strong convergent validity was observed between the leadership environment scale/subscales and both the nursing workforce index and the safety organising scale. Reliability of the leadership environment scale and subscales was strong, with all alphas ≥.85. The leadership environment scale is structurally sound and reliable. Nursing management can employ adaptive complexity leadership attributes, measure their influence on the leadership environment, subsequently modify system supports and relationships and improve the quality of health care systems. The leadership environment scale is an innovative fit to complex adaptive systems and how nurses act as leaders within these systems. © 2017 John Wiley & Sons Ltd.

  2. Trends in the thermodynamic stability of ultrathin supported oxide films

    DOE PAGES

    Plessow, Philipp N.; Bajdich, Michal; Greene, Joshua; ...

    2016-05-05

    The formation of thin oxide films on metal supports is an important phenomenon, especially in the context of strong metal support interaction (SMSI). Computational predictions of the stability of these films are hampered by their structural complexity and a varying lattice mismatch with different supports. In this study, we report a large combination of supports and ultrathin oxide films studied with density functional theory (DFT). Trends in stability are investigated through a descriptor-based analysis. Since the studied films are bound to the support exclusively through metal–metal interaction, the adsorption energy of the oxide-constituting metal atom can be expected to bemore » a reasonable descriptor for the stability of the overlayers. If the same supercell is used for all supports, the overlayers experience different amounts of stress. Using supercells with small lattice mismatch for each system leads to significantly improved scaling relations for the stability of the overlayers. Finally, this approach works well for the studied systems and therefore allows the descriptor-based exploration of the thermodynamic stability of supported thin oxide layers.« less

  3. Recent Changes in New Jersey Welfare and Work, Child Care, and Child Welfare Systems. State Update No. 7. Assessing the New Federalism: An Urban Institute Program To Assess Changing Social Policies.

    ERIC Educational Resources Information Center

    Koralek, Robin; Pindus, Nancy; Capizzano, Jeffrey; Bess, Roseana

    New Jersey has a history of successfully providing a strong safety net to support low-income families on welfare and the working poor. Despite its emphasis on work and responsibility, it has maintained a high level of support for many public assistance programs. The governor changed the emphasis of New Jersey's welfare program from education and…

  4. ‘We identify, discuss, act and promise to prevent similar deaths’: a qualitative study of Ethiopia's Maternal Death Surveillance and Response system

    PubMed Central

    Abebe, Berhanu; Busza, Joanna; Hadush, Azmach; Usmael, Abdurehman; Zeleke, Amsalu Belew; Sita, Sahle; Hailu, Solomon; Graham, Wendy J

    2017-01-01

    Introduction Ethiopia introduced national Maternal Death Surveillance and Response (MDSR) in 2013 and is among the first sub-Saharan African countries to capture data on facility-based and community-based maternal deaths. We interviewed frontline MDSR implementers about their experiences of the first 2 years of MDSR, including perceptions of its introduction and outcomes for health services. Methods We conducted a qualitative case study in 4 zones in the largest regions, interviewing 69 key informants from regional, zonal, district and facility levels. Results A defining feature of Ethiopia's MDSR system is its integration within existing disease surveillance, with both benefits and challenges. Facilitators of the system's introduction were strong political support, alignment with broader health strategies and strong links across health system departments. Barriers included confusion around new responsibilities, high staff turnover and fear of legal repercussions. Stakeholders believed MDSR increased confidence in using local data to improve maternal health services and enhanced communication across the health system. Conclusions MDSR systems take time to establish, encountering challenges in early implementation. Ensuring MDSR has a clear purpose, explicitly defined roles and responsibilities, and adequate supervisory support from the start will ensure it becomes embedded within the health system as routine practice rather than perceived as a stand-alone system. Countries planning to adopt or extend MDSR can learn from Ethiopia's experience, particularly the decision to make maternal mortality a weekly reportable condition within Public Health Emergency Management. PMID:28589016

  5. PT -symmetric gain and loss in a rotating Bose-Einstein condensate

    NASA Astrophysics Data System (ADS)

    Haag, Daniel; Dast, Dennis; Cartarius, Holger; Wunner, Günter

    2018-03-01

    PT -symmetric quantum mechanics allows finding stationary states in mean-field systems with balanced gain and loss of particles. In this work we apply this method to rotating Bose-Einstein condensates with contact interaction which are known to support ground states with vortices. Due to the particle exchange with the environment transport phenomena through ultracold gases with vortices can be studied. We find that even strongly interacting rotating systems support stable PT -symmetric ground states, sustaining a current parallel and perpendicular to the vortex cores. The vortices move through the nonuniform particle density and leave or enter the condensate through its borders creating the required net current.

  6. Numerical time evolution of ETH spin chains by means of matrix product density operators

    NASA Astrophysics Data System (ADS)

    White, Christopher; Zaletel, Michael; Mong, Roger; Refael, Gil

    We introduce a method for approximating density operators of 1D systems that, when combined with a standard framework for time evolution (TEBD), makes possible simulation of the dynamics of strongly thermalizing systems to arbitrary times. We demonstrate that the method works on both near-equilibrium initial states (Gibbs states with spatially varying temperatures) and far-from-equilibrium initial states, including quenches across phase transitions and pure states. This work was supported by the National Science Foundation Graduate Research Fellowship under Grant No. DGE \\x901144469 and by the Caltech IQIM, an NSF Physics Frontiers Center with support of the Gordon and Betty Moore.

  7. Creating institutions of care: The case for democratic forest trusts

    Treesearch

    Gus diZerega

    2007-01-01

    Strong institutional and systemic barriers prevent traditional political and economic institutions from effectively managing national forests in the United States. Despite consistent support for ecological values by the public, Congress does not protect them, and existing political institutions are not designed to respond effectively to citizens with these concerns....

  8. Bridging the Innovation Gap--An Interview with Robert Johnston.

    ERIC Educational Resources Information Center

    Larson, Cynthia M.

    1993-01-01

    This interview with a founding partner of a consulting firm specializing in product and process innovation discusses the need for American businesses to rethink their one-shot approach to innovation and implement instead a systems approach to supporting and managing innovation. A strong collaborative effort that reaches throughout the organization…

  9. The Influence of Township Schools on the Resilience of Their Learners

    ERIC Educational Resources Information Center

    Mampane, Ruth; Bouwer, Cecilia

    2011-01-01

    Many learners living in townships require protection and resilience to overcome obstacles and adversities in their context of development. The literature on resilience indicates strongly that resilience is embedded systemically. In the absence of constructive and supportive conditions in the home environment, the school would logically appear to…

  10. Characteristics of Future Ready Leadership: A Research Synthesis

    ERIC Educational Resources Information Center

    Office of Educational Technology, US Department of Education, 2017

    2017-01-01

    Strong leadership is essential to systemic, sustainable change in education. Superintendents and their leadership teams, with the support of state and local leaders, are key to leading the transition to digital learning in their districts. Superintendents throughout the country have expressed the desire for evidence-based approaches they can rely…

  11. Graduate Medical Education That Meets the Nation's Health Needs

    ERIC Educational Resources Information Center

    Eden, Jill, Ed.; Berwick, Donald, Ed.; Wilensky, Gail, Ed.

    2014-01-01

    Today's physician education system produces trained doctors with strong scientific underpinnings in biological and physical sciences as well as supervised practical experience in delivering care. Significant financial public support underlies the graduate-level training of the nation's physicians. Two federal programs--Medicare and…

  12. Gender, social support, and depression in criminal justice-involved adolescents.

    PubMed

    Johnson, Jennifer E; Esposito-Smythers, Christianne; Miranda, Robert; Rizzo, Christie J; Justus, Alicia N; Clum, George

    2011-10-01

    Knowing where criminal justice-involved teens look for support and whether those supports reduce depression has important and possibly gender-specific treatment implications for this vulnerable population. This study examines the relationships between social support and depression in a mixed-gender sample of 198 incarcerated adolescents. Greater support from families and overall and greater satisfaction with supports predicted lower depression for boys and girls. Support from siblings and extended family strongly predicted lower depression; support from parents and from friends was either not related or only weakly related to depression. Girls reported higher levels of depression, more support from friends and extended family, and less support from parents than did boys. Family, sibling, and overall support were stronger predictors of depression for girls than for boys. Results suggest that nonparent family members, especially siblings and extended family, provide important emotional resources for teens in the criminal justice system. © 2011 SAGE Publications

  13. Research on tobacco enterprise spatial decision support system based on GIS

    NASA Astrophysics Data System (ADS)

    Mei, Xin; Cui, Weihong

    2006-10-01

    Tobacco enterprise is a special enterprise, which has strong correlation to regional geography. But in the past research and application, the combination between tobacco and GIS is limited to use digital maps to assist cigarette distribution. How to comprehensively import 3S technique taking GIS as representation to construct spatial decision support system of tobacco enterprise is the main research aspect in this paper. The paper concretely analyzes the GIS requirements in tobacco enterprise for planning location of production, monitoring production management and product sale at the beginning. Then holistic solution is presented and frame design for tobacco enterprise spatial decision is given. At last the example of tobacco enterprise spatial CRM (client relation management) system is set up.

  14. X-ray Diffraction System for Advanced Materials Analysis in Research and Education

    DTIC Science & Technology

    2016-05-27

    on education. These courses have are important because they prepare students for industry and, as they move to more research - intensive work, the...real-life experimental research experience with emphasis on nanoscale device fabrication. The course provides a strong background in devices with...institution, and will support future research initiatives based on a 5-year warranty and broad base of university funding to projects. The system is

  15. Examining the impact of child parent relationship therapy (CPRT) on family functioning.

    PubMed

    Cornett, Nick; Bratton, Sue C

    2014-07-01

    Research supports that child parent relationship therapy (CPRT), a filial therapy approach, has strong effects on participating parents and children. Some speculate that filial therapy improves the family system; however, minimal research exists to support this claim. Using a single-case design, researchers examined CPRT's impact on the functioning of 8 families. Results revealed that 6 families experienced statistically significant improvements in targeted areas of family functioning. Results from self-reported measures indicated that 7 families improved in family satisfaction, 4 in cohesion, 3 in communication, and 1 in flexibility. Observational measures also revealed improvements: 5 families in flexibility, 4 families in cohesion, and 4 families in communication. The results support that the benefits of CPRT may extend to the family system. © 2013 American Association for Marriage and Family Therapy.

  16. THE CODE OF THE STREET AND INMATE VIOLENCE: INVESTIGATING THE SALIENCE OF IMPORTED BELIEF SYSTEMS*

    PubMed Central

    MEARS, DANIEL P.; STEWART, ERIC A.; SIENNICK, SONJA E.; SIMONS, RONALD L.

    2013-01-01

    Scholars have long argued that inmate behaviors stem in part from cultural belief systems that they “import” with them into incarcerative settings. Even so, few empirical assessments have tested this argument directly. Drawing on theoretical accounts of one such set of beliefs—the code of the street—and on importation theory, we hypothesize that individuals who adhere more strongly to the street code will be more likely, once incarcerated, to engage in violent behavior and that this effect will be amplified by such incarceration experiences as disciplinary sanctions and gang involvement, as well as the lack of educational programming, religious programming, and family support. We test these hypotheses using unique data that include measures of the street code belief system and incarceration experiences. The results support the argument that the code of the street belief system affects inmate violence and that the effect is more pronounced among inmates who lack family support, experience disciplinary sanctions, and are gang involved. Implications of these findings are discussed. PMID:24068837

  17. NLOphoric multichromophoric auxiliary methoxy aided triphenylamine D-π-A chromophores - Spectroscopic and computational studies

    NASA Astrophysics Data System (ADS)

    Erande, Yogesh; Kothavale, Shantaram; Sreenath, Mavila C.; Chitrambalam, Subramaniyan; Joe, Isaac H.; Sekar, Nagaiyan

    2017-11-01

    Molecules containing methoxy supported triphenylamine as strong electron-donor and dicyanovinyl as electron-acceptor groups interacting via isophorone as a configurationally locked polyene π-conjugated bridge are studied for their nonlinear optical properties. The photophysical study of examined chromophores in non-polar and polar solvents suggest that they exhibit strong emission solvatochromism and significant charge transfer characteristics supported by Lippert-Mataga plots and Generalised Mulliken Hush analysis. Linear and nonlinear optical properties as well as electronic properties measured by spectroscopic methods and cyclic voltametry and supported by DFT calculation were used to elucidate the structure property relationships. All three chromophores exhibit very high thermal stabilities with the decomposition temperatures higher than 340°C. The vibrational motions play very important role in determining the overall NLO response styryl chromophores which was established by DFT study. Dye 3 with maximum nonlinear optical susceptibility among three D-π-A systems proves that the multibranched push-pull chromophores exhibit a higher third order nonlinear susceptibility and justifies the design strategy.

  18. California's digital divide: clinical information systems for the haves and have-nots.

    PubMed

    Miller, Robert H; D'Amato, Katherine; Oliva, Nancy; West, Christopher E; Adelson, Joel W

    2009-01-01

    Strong barriers prevent the financing of clinical information systems (CIS) in health care delivery system organizations in market segments serving disadvantaged patients. These segments include community health centers, public hospitals, unaffiliated rural hospitals, and some Medicaid-oriented solo and small-group medical practices. Policy interventions such as loans, grants, pay-for-performance and other reimbursement changes, and support services assistance will help lower these barriers. Without intervention, progress will be slow and worsen health care disparities between the advantaged and disadvantaged populations.

  19. Complex agro-ecosystems for food security in a changing climate

    PubMed Central

    Khumairoh, Uma; Groot, Jeroen CJ; Lantinga, Egbert A

    2012-01-01

    Attempts to increase food crop yields by intensifying agricultural systems using high inputs of nonrenewable resources and chemicals frequently lead to de-gradation of natural resources, whereas most technological innovations are not accessible for smallholders that represent the majority of farmers world wide. Alternatively, cocultures consisting of assemblages of plant and animal species can support ecological processes of nutrient cycling and pest control, which may lead to increasing yields and declining susceptibility to extreme weather conditions with increasing complexity of the systems. Here we show that enhancing the complexity of a rice production system by adding combinations of compost, azolla, ducks, and fish resulted in strongly increased grain yields and revenues in a season with extremely adverse weather conditions on East Java, Indonesia. We found that azolla, duck, and fish increased plant nutrient content, tillering and leaf area expansion, and strongly reduced the density of six different pests. In the most complex system comprising all components the highest grain yield was obtained. The net revenues of this system from sales of rice grain, fish, and ducks, after correction for extra costs, were 114% higher than rice cultivation with only compost as fertilizer. These results provide more insight in the agro-ecological processes and demonstrate how complex agricultural systems can contribute to food security in a changing climate. If smallholders can be trained to manage these systems and are supported for initial investments by credits, their livelihoods can be improved while producing in an ecologically benign way. PMID:22957173

  20. Reduced Gravity Walking Simulator

    NASA Image and Video Library

    1965-10-15

    Cable system which supports the test subject on the Reduced Gravity Walking Simulator. The purpose of this simulator was to study the subject while walking, jumping or running. Researchers conducted studies of various factors such as fatigue limit, energy expenditure, and speed of locomotion. A.W. Vigil described the purpose of the simulator as follows: "When the astronauts land on the moon they will be in an unfamiliar environment involving, particularly, a gravitational field only one-sixth as strong as on earth. A novel method of simulating lunar gravity has been developed and is supported by a puppet-type suspension system at the end of a long pendulum. A floor is provided at the proper angle so that one-sixth of the subject's weight is supported by the floor with the remainder being supported by the suspension system. This simulator allows almost complete freedom in vertical translation and pitch and is considered to be a very realistic simulation of the lunar walking problem. For this problem this simulator suffers only slightly from the restrictions in lateral movement it puts on the test subject. This is not considered a strong disadvantage for ordinary walking problems since most of the motions do, in fact, occur in the vertical plane. However, this simulation technique would be severely restrictive if applied to the study of the extra-vehicular locomotion problem, for example, because in this situation complete six degrees of freedom are rather necessary. This technique, in effect, automatically introduces a two-axis attitude stabilization system into the problem. The technique could, however, be used in preliminary studies of extra-vehicular locomotion where, for example, it might be assumed that one axis of the attitude control system on the astronaut maneuvering unit may have failed." -- Published in James R. Hansen, Spaceflight Revolution: NASA Langley Research Center From Sputnik to Apollo, (Washington: NASA, 1995); A.W. Vigil, "Discussion of Existing and Planned Simulators for Space Research," Paper presented at Conference on the Role of Simulation in Space Technology," Blacksburg, VA, August 17-21, 1964.

  1. Reforming health care financing in Bulgaria: the population perspective.

    PubMed

    Balabanova, Dina; McKee, Martin

    2004-02-01

    Health financing reform in Bulgaria has been characterised by lack of political consensus on reform direction, economic shocks, and, since 1998, steps towards social insurance. As in other eastern European countries, the reform has been driven by an imperative to embrace new ideas modelled on systems elsewhere, but with little attention to whether these reflect popular values. This study explores underlying values, such as views on the role of the state and solidarity, attitudes to, and understanding of compulsory and voluntary insurance, and co-payments. The study identifies general principles (equity, transparency) considered important by the population and practical aspects of implementation of reform. Data were obtained from a representative survey (n=1547) and from 58 in-depth interviews and 6 focus groups with users and health professionals, conducted in 1997 before the actual reform of the health financing system in Bulgaria. A majority supports significant state involvement in health care financing, ranging from providing safety net for the poor, through co-subsidising or regulating the social insurance system, to providing state-financed universal free care (half of all respondents). Collectivist values in Bulgaria remain strong, with support for free access to services regardless of income, age, or health status and progressive funding. There is strong support (especially among the well off) for a social insurance system based on the principle of solidarity and accountability rather than the former tax-based model. The preferred health insurance fund was autonomous, state regulated, financing only health care, and offering optional membership. Voluntary insurance and, less so, co-payments were acceptable if limited to selected services and better off groups. In conclusion, a health financing system under public control that fits well with values and population preferences is likely to improve compliance and be more sustainable. Universal health insurance appears to attract most support, but a broader public debate involving less empowered people is needed to resolve misunderstandings and create realistic expectations.

  2. Exploring Systems That Support Good Clinical Care in Indigenous Primary Health-care Services: A Retrospective Analysis of Longitudinal Systems Assessment Tool Data from High-Improving Services.

    PubMed

    Woods, Cindy; Carlisle, Karen; Larkins, Sarah; Thompson, Sandra Claire; Tsey, Komla; Matthews, Veronica; Bailie, Ross

    2017-01-01

    Continuous Quality Improvement is a process for raising the quality of primary health care (PHC) across Indigenous PHC services. In addition to clinical auditing using plan, do, study, and act cycles, engaging staff in a process of reflecting on systems to support quality care is vital. The One21seventy Systems Assessment Tool (SAT) supports staff to assess systems performance in terms of five key components. This study examines quantitative and qualitative SAT data from five high-improving Indigenous PHC services in northern Australia to understand the systems used to support quality care. High-improving services selected for the study were determined by calculating quality of care indices for Indigenous health services participating in the Audit and Best Practice in Chronic Disease National Research Partnership. Services that reported continuing high improvement in quality of care delivered across two or more audit tools in three or more audits were selected for the study. Precollected SAT data (from annual team SAT meetings) are presented longitudinally using radar plots for quantitative scores for each component, and content analysis is used to describe strengths and weaknesses of performance in each systems' component. High-improving services were able to demonstrate strong processes for assessing system performance and consistent improvement in systems to support quality care across components. Key strengths in the quality support systems included adequate and orientated workforce, appropriate health system supports, and engagement with other organizations and community, while the weaknesses included lack of service infrastructure, recruitment, retention, and support for staff and additional costs. Qualitative data revealed clear voices from health service staff expressing concerns with performance, and subsequent SAT data provided evidence of changes made to address concerns. Learning from the processes and strengths of high-improving services may be useful as we work with services striving to improve the quality of care provided in other areas.

  3. Strong quantum scarring by local impurities

    PubMed Central

    Luukko, Perttu J. J.; Drury, Byron; Klales, Anna; Kaplan, Lev; Heller, Eric J.; Räsänen, Esa

    2016-01-01

    We discover and characterise strong quantum scars, or quantum eigenstates resembling classical periodic orbits, in two-dimensional quantum wells perturbed by local impurities. These scars are not explained by ordinary scar theory, which would require the existence of short, moderately unstable periodic orbits in the perturbed system. Instead, they are supported by classical resonances in the unperturbed system and the resulting quantum near-degeneracy. Even in the case of a large number of randomly scattered impurities, the scars prefer distinct orientations that extremise the overlap with the impurities. We demonstrate that these preferred orientations can be used for highly efficient transport of quantum wave packets across the perturbed potential landscape. Assisted by the scars, wave-packet recurrences are significantly stronger than in the unperturbed system. Together with the controllability of the preferred orientations, this property may be very useful for quantum transport applications. PMID:27892510

  4. Strong quantum scarring by local impurities

    NASA Astrophysics Data System (ADS)

    Luukko, Perttu J. J.; Drury, Byron; Klales, Anna; Kaplan, Lev; Heller, Eric J.; Räsänen, Esa

    2016-11-01

    We discover and characterise strong quantum scars, or quantum eigenstates resembling classical periodic orbits, in two-dimensional quantum wells perturbed by local impurities. These scars are not explained by ordinary scar theory, which would require the existence of short, moderately unstable periodic orbits in the perturbed system. Instead, they are supported by classical resonances in the unperturbed system and the resulting quantum near-degeneracy. Even in the case of a large number of randomly scattered impurities, the scars prefer distinct orientations that extremise the overlap with the impurities. We demonstrate that these preferred orientations can be used for highly efficient transport of quantum wave packets across the perturbed potential landscape. Assisted by the scars, wave-packet recurrences are significantly stronger than in the unperturbed system. Together with the controllability of the preferred orientations, this property may be very useful for quantum transport applications.

  5. Strong quantum scarring by local impurities.

    PubMed

    Luukko, Perttu J J; Drury, Byron; Klales, Anna; Kaplan, Lev; Heller, Eric J; Räsänen, Esa

    2016-11-28

    We discover and characterise strong quantum scars, or quantum eigenstates resembling classical periodic orbits, in two-dimensional quantum wells perturbed by local impurities. These scars are not explained by ordinary scar theory, which would require the existence of short, moderately unstable periodic orbits in the perturbed system. Instead, they are supported by classical resonances in the unperturbed system and the resulting quantum near-degeneracy. Even in the case of a large number of randomly scattered impurities, the scars prefer distinct orientations that extremise the overlap with the impurities. We demonstrate that these preferred orientations can be used for highly efficient transport of quantum wave packets across the perturbed potential landscape. Assisted by the scars, wave-packet recurrences are significantly stronger than in the unperturbed system. Together with the controllability of the preferred orientations, this property may be very useful for quantum transport applications.

  6. Characteristics of health care organizations associated with learning and development: lessons from a pilot study.

    PubMed

    Nyström, Monica

    2009-01-01

    Characteristics of health care organizations associated with an ability to learn from experiences and to develop and manage change were explored in this study. Understanding of these characteristics is necessary to identify factors influencing success in learning from the past and achieving future health care quality objectives. A literature review of the quality improvement, strategic organizational development and change management, organizational learning, and microsystems fields identified 20 organizational characteristics, grouped under (a) organizational systems, (b) key actors, and (c) change management processes. Qualitative methods, using interviews, focus group reports, and archival records, were applied to find associations between identified characteristics and 6 Swedish health care units externally evaluated as delivering high-quality care. Strong support for a characteristic was defined as units having more than 4 sources describing the characteristic as an important success factor. Eighteen characteristics had strong support from at least 2 units. The strongest evidence was found for the following: (i) key actors have long-term commitment, provide support, and make sense of ambiguous situations; (ii) organizational systems encourage employee commitment, participation, and involvement; and (iii) change management processes are employed systematically. Based on the results, a new model of "characteristics associated with learning and development in health care organizations" is proposed.

  7. Extreme Ultraviolet Imaging Telescope (EIT)

    NASA Technical Reports Server (NTRS)

    Lemen, J. R.; Freeland, S. L.

    1997-01-01

    Efforts concentrated on development and implementation of the SolarSoft (SSW) data analysis system. From an EIT analysis perspective, this system was designed to facilitate efficient reuse and conversion of software developed for Yohkoh/SXT and to take advantage of a large existing body of software developed by the SDAC, Yohkoh, and SOHO instrument teams. Another strong motivation for this system was to provide an EIT analysis environment which permits coordinated analysis of EIT data in conjunction with data from important supporting instruments, including Yohkoh/SXT and the other SOHO coronal instruments; CDS, SUMER, and LASCO. In addition, the SSW system will support coordinated EIT/TRACE analysis (by design) when TRACE data is available; TRACE launch is currently planned for March 1998. Working with Jeff Newmark, the Chianti software package (K.P. Dere et al) and UV /EUV data base was fully integrated into the SSW system to facilitate EIT temperature and emission analysis.

  8. Applying mobile and pervasive computer technology to enhance coordination of work in a surgical ward.

    PubMed

    Hansen, Thomas Riisgaard; Bardram, Jakob E

    2007-01-01

    Collaboration, coordination, and communication are crucial in maintaining an efficient and smooth flow of work in an operating ward. This coordination, however, often comes at a high price in terms of unsuccessfully trying to get hold of people, disturbing telephone calls, looking for people, and unnecessary stress. To accommodate this situation and to increase the quality of work in operating wards, we have designed a set of pervasive computer systems which supports what we call context-mediated communication and awareness. These systems use large interactive displays, video streaming from key locations, tracking systems, and mobile devices to support social awareness and different types of communication modalities relevant to the current context. In this paper we report qualitative data from a one-year deployment of the system in a local hospital. Overall, this study shows that 75% of the participants strongly agreed that these systems had made their work easier.

  9. Moving toward a Comprehensive Early Childhood System in Hawaii: An Analysis of the Fiscal Resources Supporting Young Children, Prenatal to Age Five and Their Families, in Fiscal 2011

    ERIC Educational Resources Information Center

    Connors-Tadros, Lori; Silloway, Torey; Mayman, Jennifer; Dahlin, Melissa

    2012-01-01

    A strong early childhood system that is well funded, fully coordinated, and highly accountable is essential to a state's long-term economic health. Significant research during the past decade has identified short- and long-term benefits to children, families, and communities when young children arrive at school healthy and ready to learn.…

  10. Analytical Approaches to Guide SLS Fault Management (FM) Development

    NASA Technical Reports Server (NTRS)

    Patterson, Jonathan D.

    2012-01-01

    Extensive analysis is needed to determine the right set of FM capabilities to provide the most coverage without significantly increasing the cost, reliability (FP/FN), and complexity of the overall vehicle systems. Strong collaboration with the stakeholders is required to support the determination of the best triggers and response options. The SLS Fault Management process has been documented in the Space Launch System Program (SLSP) Fault Management Plan (SLS-PLAN-085).

  11. Remarks by Deputy Commerce Secretary David A. Sampson U.S. Chamber Media Forum, next generation GPS January 25, 2006

    DOT National Transportation Integrated Search

    2006-01-25

    Innovations like the Global Positioning System are what keep the U.S. economy strong and competitive. I'd like to thank the U.S. Chamber of Commerce for hosting this event, and for its leadership in supporting policies that encourage American innovat...

  12. Framing Work-Integrated E-Learning with Techno-Pedagogical Genres

    ERIC Educational Resources Information Center

    Svensson, Lars; Ostlund, Christian

    2007-01-01

    Distance Educational Practice is today supported by a range of information systems (IS) design theories. Still, there are surprisingly few strong pedagogical ideas and constructs that are communicated across distance educational institutions. Instead it is often the technology, the software and the medium that is at the centre of attention as we…

  13. European Bilingual Models beyond "Lingua Franca": Key Findings from CLIL French Programs

    ERIC Educational Resources Information Center

    Pérez, América; Lorenzo, Francisco; Pavón, Víctor

    2016-01-01

    Content and Language Integrated Learning (CLIL) has expanded all around the continent following European Council guidelines, favored by competence studies that identified educational systems as a strong determinant for second language gains and deficits. Over the years since the turn of the century, CLIL has gained the support of language policy…

  14. New Beginnings: Using Federal Title I Funds to Support Local Pre-K Efforts. Federal Policy Series

    ERIC Educational Resources Information Center

    Gayl, Chrisanne L.; Young, Marci; Patterson, Kathy

    2009-01-01

    High-quality, voluntary pre-kindergarten has emerged as an important policy to improve the nation's education system. Based on strong evidence from rigorous longitudinal research and recent program evaluations, reform-minded principals, superintendents, school board members and other leaders have embraced early education as an effective strategy…

  15. Assisting At-Risk Community College Students: Acquisition of Critical Thinking Learning Strategies.

    ERIC Educational Resources Information Center

    Arburn, Theresa M.; Bethel, Lowell J.

    Community college students may be at-risk academically, socioeconomically, or because they are first-generation attendees. Recognizing the need for a strong support system, a study was conducted to determine whether students could be taught to incorporate information processing strategies into their personal inventory of strategies. It was…

  16. A Goal for North Carolina's Schools. First in America 2001 Progress Report.

    ERIC Educational Resources Information Center

    Cunningham, Elizabeth Kolb, Ed.; Thompson, Charles L., Ed.

    This second annual report details North Carolina's performance and progress since 2000 in the five goal areas: high student performance; every child ready to learn; safe, orderly, and caring schools; quality teachers and administrators; and strong family, business, and community support. Over the years, North Carolina's education system has…

  17. Strong Agents and Weak Systems: University Support for School Level Improvement

    ERIC Educational Resources Information Center

    Nehring, James H.; O'Brien, Ellen J.

    2012-01-01

    This study examined individual and school level factors that advance and suppress the traits of high performing schools. Based on action plans and reflective journals of 28 school level practitioners in 14 schools across 10 school districts, researchers tracked the progress of each practitioner from participation in a university-based school…

  18. Bacteria/virus filter membrane

    NASA Technical Reports Server (NTRS)

    Lysaght, M. S.; Goodwin, F.; Roebelen, G.

    1977-01-01

    Hollow acrylate fiber membrane that filters bacterial and viral organisms can be used with closed-cycle life-support systems for underwater habitations or laboratories. Membrane also has applications in fields of medicine, gnotobiotics, pharmaceutical production, and industries and research facilities that require sterile water. Device eliminates need for strong chemicals or sterilizing agents, thereby reducing costs.

  19. Buenos Aires - Toward Comprehensive Development and Sustainable Mobility

    NASA Astrophysics Data System (ADS)

    Kamrowska-Zaluska, Dorota

    2017-10-01

    This paper is introducing Buenos Aires’ achievements and challenges in implementing comprehensive development and integrating efficient and sustainable transport system within its urban structure. There are several important steps in this process starting from urban regeneration of Puerto Madero, the introduction and then implementation of a strategic plan Modelo territorial (2010) and of Buenos Aires’ Plan de Movilidad Sustentable (2013). The last one - Sustainable Mobility Plan helped Buenos Aires win several prestigious rewards for innovative approach to mobility and sustainable transport and leadership in combating climate change. Buenos Aires City government demonstrates strong leadership by implementing well-planned (Bus Rapid Transport) BRT solutions, stressing the importance of political will and support, flexibility and an open mind in listening to the points of view of all stakeholders involved. Buenos Aires has made a very important step toward sustainability by supporting development of more sustainable modes of transport, such as bicycle-sharing system and improving walkability of the city centre. The last initiative combined with strong focus on public spaces is adding to tourist attractiveness based on diversity of the capital of Argentina.

  20. Leadership Perspectives on Operationalizing the Learning Health Care System in an Integrated Delivery System.

    PubMed

    Psek, Wayne; Davis, F Daniel; Gerrity, Gloria; Stametz, Rebecca; Bailey-Davis, Lisa; Henninger, Debra; Sellers, Dorothy; Darer, Jonathan

    2016-01-01

    Healthcare leaders need operational strategies that support organizational learning for continued improvement and value generation. The learning health system (LHS) model may provide leaders with such strategies; however, little is known about leaders' perspectives on the value and application of system-wide operationalization of the LHS model. The objective of this project was to solicit and analyze senior health system leaders' perspectives on the LHS and learning activities in an integrated delivery system. A series of interviews were conducted with 41 system leaders from a broad range of clinical and administrative areas across an integrated delivery system. Leaders' responses were categorized into themes. Ten major themes emerged from our conversations with leaders. While leaders generally expressed support for the concept of the LHS and enhanced system-wide learning, their concerns and suggestions for operationalization where strongly aligned with their functional area and strategic goals. Our findings suggests that leaders tend to adopt a very pragmatic approach to learning. Leaders expressed a dichotomy between the operational imperative to execute operational objectives efficiently and the need for rigorous evaluation. Alignment of learning activities with system-wide strategic and operational priorities is important to gain leadership support and resources. Practical approaches to addressing opportunities and challenges identified in the themes are discussed. Continuous learning is an ongoing, multi-disciplinary function of a health care delivery system. Findings from this and other research may be used to inform and prioritize system-wide learning objectives and strategies which support reliable, high value care delivery.

  1. Reorienting health systems to meet the demand for consumer health solutions.

    PubMed

    Buckeridge, David L

    2014-01-01

    There is a clear and pronounced gap between the demand for and access to consumer health solutions. Existing health information systems and broader health system factors such as funding models are reasons for this gap. There are strong arguments from the perspectives of the consumer and population health for closing this gap, but the case from the perspective of the current health system is mixed. Closing the gap will require a concerted effort to reorient health information systems and funding models to support online access by consumers to health information and health services.

  2. Individual and community resilience factors among lesbian, gay, bisexual, queer and questioning youth and adults in Israel.

    PubMed

    Shilo, Guy; Antebi, Nadav; Mor, Zohar

    2015-03-01

    Drawing on resilience theories, this study examined the individual and community factors of Israeli lesbians, gays, bisexuals, queers, and questioning (LGBQs) that contribute to positive mental health and the degree to which individual and community protective factors mitigate the adverse effect of risk factors for poor mental health. Differences in resilience factors between LGBQ youth and adults were explored. Data were collected on 890 LGBQ youth and adults. Findings emphasize the role of community-level resilience factors in the lives of LGBQs, and that these support systems differ slightly between the two age groups. Among youth, family support was both a strong predictor for well-being and a protective factor for mental distress. Although family support was found as a resilience factor among adults as well, other community-level factors (friends' support, LGBT connectedness and having steady partner) were found as protective factors for poorer mental health. These findings suggest for efforts on fostering familial support for LGBQ youth and a multi-level system that offers support at the familial, peer, relationship and community levels for both LGBQ youth and adults.

  3. A massive pulsar in a compact relativistic binary.

    PubMed

    Antoniadis, John; Freire, Paulo C C; Wex, Norbert; Tauris, Thomas M; Lynch, Ryan S; van Kerkwijk, Marten H; Kramer, Michael; Bassa, Cees; Dhillon, Vik S; Driebe, Thomas; Hessels, Jason W T; Kaspi, Victoria M; Kondratiev, Vladislav I; Langer, Norbert; Marsh, Thomas R; McLaughlin, Maura A; Pennucci, Timothy T; Ransom, Scott M; Stairs, Ingrid H; van Leeuwen, Joeri; Verbiest, Joris P W; Whelan, David G

    2013-04-26

    Many physically motivated extensions to general relativity (GR) predict substantial deviations in the properties of spacetime surrounding massive neutron stars. We report the measurement of a 2.01 ± 0.04 solar mass (M⊙) pulsar in a 2.46-hour orbit with a 0.172 ± 0.003 M⊙ white dwarf. The high pulsar mass and the compact orbit make this system a sensitive laboratory of a previously untested strong-field gravity regime. Thus far, the observed orbital decay agrees with GR, supporting its validity even for the extreme conditions present in the system. The resulting constraints on deviations support the use of GR-based templates for ground-based gravitational wave detectors. Additionally, the system strengthens recent constraints on the properties of dense matter and provides insight to binary stellar astrophysics and pulsar recycling.

  4. Geographic information system development in the CARETS project

    USGS Publications Warehouse

    Mitchell, William B.; Fegeas, Robin G.; Fitzpatrick, Katherine A.; Hallam, Cheryl A.

    1977-01-01

    Experience in the development of a geographic information system to support the CARETS project has confirmed the considerable advantages that may accrue by paralleling the system development with a rational and balanced system production effort which permits the integration of the education and training of users with interim deliverable products to them. Those advantages include support for a long-term staff plan that recognizes substantial staff changes through system development and implementation, a fiscal plan that provides continuity in resources necessary for total system development, and a feedback system which allows the user to communicate his experiences in using the system. Thus far balance between system development and system production has not been achieved because of continuing large-scale spatial data processing requirements coupled with strong and insistent demands from users for immediately deliverable products from the system. That imbalance has refocussed staffing and fiscal plans from long-term system development to short- and near-term production requirements, continuously extends total system development time, and increases the possibility that later system development may reduce the usefulness of current interim products.

  5. Ground test facility for SEI nuclear rocket engines

    NASA Astrophysics Data System (ADS)

    Harmon, Charles D.; Ottinger, Cathy A.; Sanchez, Lawrence C.; Shipers, Larry R.

    1992-07-01

    Nuclear (fission) thermal propulsion has been identified as a critical technology for a manned mission to Mars by the year 2019. Facilities are required that will support ground tests to qualify the nuclear rocket engine design, which must support a realistic thermal and neutronic environment in which the fuel elements will operate at a fraction of the power for a flight weight reactor/engine. This paper describes the design of a fuel element ground test facility, with a strong emphasis on safety and economy. The details of major structures and support systems of the facility are discussed, and a design diagram of the test facility structures is presented.

  6. Intelligent content fitting for digital publishing

    NASA Astrophysics Data System (ADS)

    Lin, Xiaofan

    2006-02-01

    One recurring problem in Variable Data Printing (VDP) is that the existing contents cannot satisfy the VDP task as-is. So there is a strong need for content fitting technologies to support high-value digital publishing applications, in which text and image are the two major types of contents. This paper presents meta-Autocrop framework for image fitting and TextFlex technology for text fitting. The meta-Autocrop framework supports multiple modes: fixed aspect-ratio mode, advice mode, and verification mode. The TextFlex technology supports non-rectangular text wrapping and paragraph-based line breaking. We also demonstrate how these content fitting technologies are utilized in the overall automated composition and layout system.

  7. Public perceptions of quarantine: community-based telephone survey following an infectious disease outbreak.

    PubMed

    Tracy, C Shawn; Rea, Elizabeth; Upshur, Ross E G

    2009-12-16

    The use of restrictive measures such as quarantine draws into sharp relief the dynamic interplay between the individual rights of the citizen on the one hand and the collective rights of the community on the other. Concerns regarding infectious disease outbreaks (SARS, pandemic influenza) have intensified the need to understand public perceptions of quarantine and other social distancing measures. We conducted a telephone survey of the general population in the Greater Toronto Area in Ontario, Canada. Computer-assisted telephone interviewing (CATI) technology was used. A final sample of 500 individuals was achieved through standard random-digit dialing. Our data indicate strong public support for the use of quarantine when required and for serious legal sanctions against those who fail to comply. This support is contingent both on the implementation of legal safeguards to protect against inappropriate use and on the provision of psychosocial supports for those affected. To engender strong public support for quarantine and other restrictive measures, government officials and public health policy-makers would do well to implement a comprehensive system of supports and safeguards, to educate and inform frontline public health workers, and to engage the public at large in an open dialogue on the ethical use of restrictive measures during infectious disease outbreaks.

  8. Public perceptions of quarantine: community-based telephone survey following an infectious disease outbreak

    PubMed Central

    2009-01-01

    Background The use of restrictive measures such as quarantine draws into sharp relief the dynamic interplay between the individual rights of the citizen on the one hand and the collective rights of the community on the other. Concerns regarding infectious disease outbreaks (SARS, pandemic influenza) have intensified the need to understand public perceptions of quarantine and other social distancing measures. Methods We conducted a telephone survey of the general population in the Greater Toronto Area in Ontario, Canada. Computer-assisted telephone interviewing (CATI) technology was used. A final sample of 500 individuals was achieved through standard random-digit dialing. Results Our data indicate strong public support for the use of quarantine when required and for serious legal sanctions against those who fail to comply. This support is contingent both on the implementation of legal safeguards to protect against inappropriate use and on the provision of psychosocial supports for those affected. Conclusion To engender strong public support for quarantine and other restrictive measures, government officials and public health policy-makers would do well to implement a comprehensive system of supports and safeguards, to educate and inform frontline public health workers, and to engage the public at large in an open dialogue on the ethical use of restrictive measures during infectious disease outbreaks. PMID:20015400

  9. A Religious Worldview: Protecting One's Meaning System Through Religious Prejudice.

    PubMed

    Goplen, Joanna; Plant, E Ashby

    2015-11-01

    For some people, religion strongly influences their worldviews. We propose that religious outgroups threaten the foundational beliefs of people with strong religious worldviews (RWVs) by endorsing alternative belief systems and that this threat contributes to religious prejudice. To examine these ideas, we developed a measure of RWV strength and assessed the role of RWV threat in religious prejudice. Across five studies, strength of RWV was related to religious prejudice, including derogation and denial of alternative religious viewpoints, as well as support for suppressing, avoiding, and even aggressing against religious outgroups. These responses were strongest toward religious outgroups whose worldviews were the most different, and therefore most threatening. Mediational analyses revealed that strong RWV people expressed heightened prejudice because of the worldview threat posed by religious outgroup members. These findings indicate that the avoidance and subjugation of religious outgroups can serve as a worldview protection strategy for some people. © 2015 by the Society for Personality and Social Psychology, Inc.

  10. Partitioning in Avionics Architectures: Requirements, Mechanisms, and Assurance

    NASA Technical Reports Server (NTRS)

    Rushby, John

    1999-01-01

    Automated aircraft control has traditionally been divided into distinct "functions" that are implemented separately (e.g., autopilot, autothrottle, flight management); each function has its own fault-tolerant computer system, and dependencies among different functions are generally limited to the exchange of sensor and control data. A by-product of this "federated" architecture is that faults are strongly contained within the computer system of the function where they occur and cannot readily propagate to affect the operation of other functions. More modern avionics architectures contemplate supporting multiple functions on a single, shared, fault-tolerant computer system where natural fault containment boundaries are less sharply defined. Partitioning uses appropriate hardware and software mechanisms to restore strong fault containment to such integrated architectures. This report examines the requirements for partitioning, mechanisms for their realization, and issues in providing assurance for partitioning. Because partitioning shares some concerns with computer security, security models are reviewed and compared with the concerns of partitioning.

  11. Influence of Controlled Viscous Dissipation on Propagation of Strongly Nonlinear Waves in Steel-Based Phononic Crystals

    NASA Astrophysics Data System (ADS)

    Herbold, Eric

    2005-07-01

    Strongly nonlinear phononic crystals were assembled from chains of stainless steel spheres with diameter 4.78 mm. Propagation of solitary waves and splitting of initial pulse into train of solitary waves excited by the impact of piston was investigated in different viscous media in experiments and in numerical calculations. Oil of various grades was used to introduce controlled dissipation into the system. Preliminary results indicate that splitting of the initial pulse into the train of solitary waves was dramatically influenced by viscosity. This work was supported by NSF (Grant No. DCMS03013220).

  12. Leaf hydraulic conductance varies with vein anatomy across Arabidopsis thaliana wild-type and leaf vein mutants.

    PubMed

    Caringella, Marissa A; Bongers, Franca J; Sack, Lawren

    2015-12-01

    Leaf venation is diverse across plant species and has practical applications from paleobotany to modern agriculture. However, the impact of vein traits on plant performance has not yet been tested in a model system such as Arabidopsis thaliana. Previous studies analysed cotyledons of A. thaliana vein mutants and identified visible differences in their vein systems from the wild type (WT). We measured leaf hydraulic conductance (Kleaf ), vein traits, and xylem and mesophyll anatomy for A. thaliana WT (Col-0) and four vein mutants (dot3-111 and dot3-134, and cvp1-3 and cvp2-1). Mutant true leaves did not possess the qualitative venation anomalies previously shown in the cotyledons, but varied quantitatively in vein traits and leaf anatomy across genotypes. The WT had significantly higher mean Kleaf . Across all genotypes, there was a strong correlation of Kleaf with traits related to hydraulic conductance across the bundle sheath, as influenced by the number and radial diameter of bundle sheath cells and vein length per area. These findings support the hypothesis that vein traits influence Kleaf , indicating the usefulness of this mutant system for testing theory that was primarily established comparatively across species, and supports a strong role for the bundle sheath in influencing Kleaf . © 2015 John Wiley & Sons Ltd.

  13. Subseafloor fluid mixing and fossilized microbial life in a Cretaceous 'Lost City'-type hydrothermal system at the Iberian Margin

    NASA Astrophysics Data System (ADS)

    Klein, F.; Humphris, S. E.; Guo, W.; Schubotz, F.; Schwarzenbach, E. M.; Orsi, W.

    2015-12-01

    Subseafloor mixing of reduced hydrothermal fluids with seawater is believed to provide the energy and substrates needed to support autotrophic microorganisms in the hydrated oceanic mantle (serpentinite). Despite the potentially significant implications for the distribution of microbial life on Earth and other water-bearing planetary bodies, our understanding of such environments remains elusive. In the present study we examined fossilized microbial communities and fluid mixing processes in the subseafloor of a Cretaceous 'Lost City'-type hydrothermal system at the passive Iberia Margin (ODP Leg 149, Hole 897D). Brucite and calcite co-precipitated from mixed fluids ca. 65m below the Cretaceous palaeo-seafloor at temperatures of 32±4°C within steep chemical gradients (fO2, pH, CH4, SO4, ΣCO2, etc) between weathered, carbonate-rich serpentinite breccia and serpentinite. Mixing of oxidized seawater and strongly reducing hydrothermal fluid at moderate temperatures created conditions capable of supporting microbial activity within the oceanic basement. Dense microbial colonies are fossilized in brucite-calcite veins that are strongly enriched in organic carbon but depleted in 13C. We detected a combination of bacterial diether lipid biomarkers, archaeol and archaeal tetraethers analogous to those found in brucite-carbonate chimneys at the active Lost City hydrothermal field. The exposure of mantle rocks to seawater during the breakup of Pangaea fueled chemolithoautotrophic microbial communities at the Iberia Margin during the Cretaceous, possibly before the onset of seafloor spreading in the Atlantic. 'Lost City'-type serpentinization systems have been discovered at mid-ocean ridges, in forearc settings of subduction zones and at continental margins. It appears that, wherever they occur, they can support microbial life, even in deep subseafloor environments as demonstrated in the present study. Because equivalent systems have likely existed throughout most of Earth's history, fluid mixing may have provided the substrates and energy to support a unique subseafloor community of microorganisms over geological timescales.

  14. Subseafloor fluid mixing and fossilized microbial life in a Cretaceous 'Lost City'-type hydrothermal system at the Iberian Margin

    NASA Astrophysics Data System (ADS)

    Klein, F.; Humphris, S. E.; Guo, W.; Schubotz, F.; Schwarzenbach, E. M.; Orsi, W.

    2014-12-01

    Subseafloor mixing of reduced hydrothermal fluids with seawater is believed to provide the energy and substrates needed to support autotrophic microorganisms in the hydrated oceanic mantle (serpentinite). Despite the potentially significant implications for the distribution of microbial life on Earth and other water-bearing planetary bodies, our understanding of such environments remains elusive. In the present study we examined fossilized microbial communities and fluid mixing processes in the subseafloor of a Cretaceous 'Lost City'-type hydrothermal system at the passive Iberia Margin (ODP Leg 149, Hole 897D). Brucite and calcite co-precipitated from mixed fluids ca. 65m below the Cretaceous palaeo-seafloor at temperatures of 32±4°C within steep chemical gradients (fO2, pH, CH4, SO4, ΣCO2, etc) between weathered, carbonate-rich serpentinite breccia and serpentinite. Mixing of oxidized seawater and strongly reducing hydrothermal fluid at moderate temperatures created conditions capable of supporting microbial activity within the oceanic basement. Dense microbial colonies are fossilized in brucite-calcite veins that are strongly enriched in organic carbon but depleted in 13C. We detected a combination of bacterial diether lipid biomarkers, archaeol and archaeal tetraethers analogous to those found in brucite-carbonate chimneys at the active Lost City hydrothermal field. The exposure of mantle rocks to seawater during the breakup of Pangaea fueled chemolithoautotrophic microbial communities at the Iberia Margin during the Cretaceous, possibly before the onset of seafloor spreading in the Atlantic. 'Lost City'-type serpentinization systems have been discovered at mid-ocean ridges, in forearc settings of subduction zones and at continental margins. It appears that, wherever they occur, they can support microbial life, even in deep subseafloor environments as demonstrated in the present study. Because equivalent systems have likely existed throughout most of Earth's history, fluid mixing may have provided the substrates and energy to support a unique subseafloor community of microorganisms over geological timescales.

  15. Structural cost optimization of photovoltaic central power station modules and support structure

    NASA Technical Reports Server (NTRS)

    Sutton, P. D.; Stolte, W. J.; Marsh, R. O.

    1979-01-01

    The results of a comprehensive study of photovoltaic module structural support concepts for photovoltaic central power stations and their associated costs are presented. The objective of the study has been the identification of structural cost drivers. Parametric structural design and cost analyses of complete array systems consisting of modules, primary support structures, and foundations were performed. Area related module cost was found to be constant with design, size, and loading. A curved glass module concept was evaluated and found to have the potential to significantly reduce panel structural costs. Conclusions of the study are: array costs do not vary greatly among the designs evaluated; panel and array costs are strongly dependent on design loading; and the best support configuration is load dependent

  16. Four-Quarter School Year. Results of an Exploratory Study of the Four-Quarter School Year in Metropolitan Atlanta.

    ERIC Educational Resources Information Center

    Bentley, Ernest L; And Others

    Six Atlanta, Georgia, school systems initiated a four-quarter school year program in 1968-69. An exploratory study was conducted to develop procedures and instruments for a comprehensive examination of the plan. Strong support exists in all groups interviewed -- superintendents and steering committee members, students, parents, teachers,…

  17. Agency policy and the resolution of wilderness stewardship dilemmas

    Treesearch

    David N. Cole

    2003-01-01

    Wilderness preservation is strongly supported by the American people (Cordell et al. 1998) and a substantial portion of the public domain has been allocated to wilderness. The Wilderness Act of 1964 and more than 135 subsequent wilderness bills have created a National Wilderness Preservation System of 661 wilderness areas with a total acreage that exceeds 106 million...

  18. Predictors of International Graduate Student Success in U.S. Universities: Analysis of Noncognitive Student Variables and Institutional Characteristics

    ERIC Educational Resources Information Center

    Sanford, Rania

    2009-01-01

    Purpose. The purpose of this study was to determine the relationships between Sedlacek's (2004b) student noncognitive variables (positive self-concept, realistic self-appraisal, successfully handling the system, preference for long-term goals, leadership experience, presence of a strong support person, community service, and knowledge of the…

  19. Public Opinion and the Death Penalty: A Qualitative Approach

    ERIC Educational Resources Information Center

    Falco, Diana L.; Freiburger, Tina L.

    2011-01-01

    Strong public support for capital punishment is arguably the number one reason why the death penalty continues to be used as a form of correctional policy in the U.S. criminal justice system. Therefore, it is fundamental that the measure of death penalty opinion be heavily scrutinized. Utilizing a methodological approach not typically employed in…

  20. Hope out of Poverty

    ERIC Educational Resources Information Center

    Davenport, Roy F.; Tolbert, Marsha; Myers-Oliver, Donna; Brissett, Julia M.; Roland, Annissa J.

    2007-01-01

    In "A Framework of Poverty," Ruby Payne (1998) itemizes the things that characterize poverty-stricken people. She talks about how hard it is for a person to move out of poverty. To not pass poverty on to another generation, one must have a vision. One must have a desire to achieve a better life or a strong support system. Schools must…

  1. Building Early Learning Leaders: New Jersey's PreK-3rd Leadership Training. A Case Study

    ERIC Educational Resources Information Center

    Rice, Cynthia; Costanza, Vincent

    2011-01-01

    New Jersey school administrators are finding themselves in need of the supports necessary to build on the state's existing model preschools toward a broader vision of early learning, including making strong connections to the early learning system. Clearly, changing the educational mindset and building the related capacity of front-line leaders is…

  2. Supporting Education for Students with Children through Mobile Technology

    ERIC Educational Resources Information Center

    Varner, Brenda

    2017-01-01

    The original goal of this project was to build a peer e-mentoring program for parents and measure the effect of the program on persistence. In spite of strong mentor participation, two terms of focused recruiting did not attract mentees. This sparked the question of why those who had successfully navigated the higher education system thought a…

  3. Infants and Toddlers in the Policy Picture: A Self-Assessment Toolkit for States

    ERIC Educational Resources Information Center

    Szekely, Amanda; Gebhard, Barbara

    2016-01-01

    All infants and toddlers need good health, strong families, and positive early learning experiences. Furthermore, young children benefit most from an early childhood system that is built through collaboration. These goals form the framework for a policy agenda that creates a comprehensive range of services and supports that honor the needs and…

  4. Knowledge acquisition is governed by striatal prediction errors.

    PubMed

    Pine, Alex; Sadeh, Noa; Ben-Yakov, Aya; Dudai, Yadin; Mendelsohn, Avi

    2018-04-26

    Discrepancies between expectations and outcomes, or prediction errors, are central to trial-and-error learning based on reward and punishment, and their neurobiological basis is well characterized. It is not known, however, whether the same principles apply to declarative memory systems, such as those supporting semantic learning. Here, we demonstrate with fMRI that the brain parametrically encodes the degree to which new factual information violates expectations based on prior knowledge and beliefs-most prominently in the ventral striatum, and cortical regions supporting declarative memory encoding. These semantic prediction errors determine the extent to which information is incorporated into long-term memory, such that learning is superior when incoming information counters strong incorrect recollections, thereby eliciting large prediction errors. Paradoxically, by the same account, strong accurate recollections are more amenable to being supplanted by misinformation, engendering false memories. These findings highlight a commonality in brain mechanisms and computational rules that govern declarative and nondeclarative learning, traditionally deemed dissociable.

  5. Software for MR image overlay guided needle insertions: the clinical translation process

    NASA Astrophysics Data System (ADS)

    Ungi, Tamas; U-Thainual, Paweena; Fritz, Jan; Iordachita, Iulian I.; Flammang, Aaron J.; Carrino, John A.; Fichtinger, Gabor

    2013-03-01

    PURPOSE: Needle guidance software using augmented reality image overlay was translated from the experimental phase to support preclinical and clinical studies. Major functional and structural changes were needed to meet clinical requirements. We present the process applied to fulfill these requirements, and selected features that may be applied in the translational phase of other image-guided surgical navigation systems. METHODS: We used an agile software development process for rapid adaptation to unforeseen clinical requests. The process is based on iterations of operating room test sessions, feedback discussions, and software development sprints. The open-source application framework of 3D Slicer and the NA-MIC kit provided sufficient flexibility and stable software foundations for this work. RESULTS: All requirements were addressed in a process with 19 operating room test iterations. Most features developed in this phase were related to workflow simplification and operator feedback. CONCLUSION: Efficient and affordable modifications were facilitated by an open source application framework and frequent clinical feedback sessions. Results of cadaver experiments show that software requirements were successfully solved after a limited number of operating room tests.

  6. Spontaneous Scalarization: Dead or Alive?

    NASA Astrophysics Data System (ADS)

    Berti, Emanuele; Crispino, Luis; Gerosa, Davide; Gualtieri, Leonardo; Horbatsch, Michael; Macedo, Caio; Okada da Silva, Hector; Pani, Paolo; Sotani, Hajime; Sperhake, Ulrich

    2015-04-01

    In 1993, Damour and Esposito-Farese showed that a wide class of scalar-tensor theories can pass weak-field gravitational tests and exhibit nonperturbative strong-field deviations away from General Relativity in systems involving neutron stars. These deviations are possible in the presence of ``spontaneous scalarization,'' a phase transition similar in nature to spontaneous magnetization in ferromagnets. More than twenty years after the original proposal, binary pulsar experiments have severely constrained the possibility of spontaneous scalarization occurring in nature. I will show that these experimental constraints have important implications for the torsional oscillation frequencies of neutron stars and for the so-called ``I-Love-Q'' relations in scalar-tensor theories. I will also argue that there is still hope to observe strong scalarization effects, despite the strong experimental bounds on the original mechanism. In particular, I will discuss two mechanisms that could produce strong scalarization in neutron stars: anisotropy and multiscalarization. This work was supported by NSF CAREER Award PHY-1055103.

  7. In situ and theoretical studies for the dissociation of water on an active Ni/CeO2 catalyst: importance of strong metal-support interactions for the cleavage of O-H bonds.

    PubMed

    Carrasco, Javier; López-Durán, David; Liu, Zongyuan; Duchoň, Tomáš; Evans, Jaime; Senanayake, Sanjaya D; Crumlin, Ethan J; Matolín, Vladimir; Rodríguez, José A; Ganduglia-Pirovano, M Verónica

    2015-03-23

    Water dissociation is crucial in many catalytic reactions on oxide-supported transition-metal catalysts. Supported by experimental and density-functional theory results, the effect of the support on OH bond cleavage activity is elucidated for nickel/ceria systems. Ambient-pressure O 1s photoemission spectra at low Ni loadings on CeO2 (111) reveal a substantially larger amount of OH groups as compared to the bare support. Computed activation energy barriers for water dissociation show an enhanced reactivity of Ni adatoms on CeO2 (111) compared with pyramidal Ni4 particles with one Ni atom not in contact with the support, and extended Ni(111) surfaces. At the origin of this support effect is the ability of ceria to stabilize oxidized Ni(2+) species by accommodating electrons in localized f-states. The fast dissociation of water on Ni/CeO2 has a dramatic effect on the activity and stability of this system as a catalyst for the water-gas shift and ethanol steam reforming reactions. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. In-situ and theoretical studies for the dissociation of water on an active Ni/CeO₂ catalyst: Importance of strong metal-support interactions for the cleavage of O-H bonds

    DOE PAGES

    Carrasco, Javier; Rodriguez, Jose A.; Lopez-Duran, David; ...

    2015-03-23

    Water dissociation is crucial in many catalytic reactions on oxide-supported transition-metal catalysts. Here, supported by experimental and density-functional theory results, we elucidate the effect of the support on O-H bond cleavage activity for nickel/ceria systems. Ambient-pressure O1s photoemission spectra at low Ni loadings on CeO₂(111) reveal a substantially larger amount of OH groups as compared to the bare support. Our computed activation energy barriers for water dissociation show an enhanced reactivity of Ni adatoms on CeO₂(111) compared with pyramidal Ni₄ particles with one Ni atom not in contact with the support, and extended Ni(111) surfaces. At the origin of thismore » support effect is the ability of ceria to stabilize oxidized Ni²⁺ species by accommodating electrons in localized f-states. The fast dissociation of water on Ni/CeO₂ has a dramatic effect on the activity and stability of this system as a catalyst for the water-gas shift and ethanol steam reforming reactions.« less

  9. The influence of non-clinical patient factors on medical oncologists' decisions to recommend breast cancer adjuvant chemotherapy.

    PubMed

    Pini, T May; Hawley, Sarah T; Li, Yun; Katz, Steven J; Griggs, Jennifer J

    2012-07-01

    The extent to which medical oncologists consider non-clinical patient factors when deciding to recommend adjuvant chemotherapy is unknown. Medical oncologists who treated a population-based sample of early stage breast cancer patients reported to the Los Angeles and Detroit Surveillance, Epidemiology, and End Results registries 2005-2007 were asked how strongly they consider a patient's ability to follow instructions, level of social support, and level of work support/flexibility in decisions to recommend adjuvant chemotherapy. Responses of 4 (Quite strongly) or 5 (Very strongly) on a five-point Likert scale defined strong consideration. Associations between oncologist/practice characteristics and strong consideration of each non-clinical factor were examined. 134 oncologists (66 %) reported strong consideration of one or more factor. Ability to follow instructions was strongly considered by 120 oncologists (59 %), social support by 78 (38 %), and work support/flexibility by 73 (36 %). Larger percent of practice devoted to breast cancer was associated with lower likelihood of strongly considering ability to follow instructions [odds ratio (OR) 0.98, 95 % confidence interval (CI) 0.97-0.99; P = 0.04]. Increased years in practice was associated with lower likelihood of strongly considering social support (OR 0.96, CI 0.93-0.99; P = 0.011), while non-white race (OR 2.1, CI 1.03-4.26; P = 0.041) and tumor board access (OR 2.04, CI 1.01-4.12; P = 0.048) were associated with higher likelihood. Non-white race was associated with strongly considering work support/flexibility (OR 2.44, CI 1.21-4.92; P = 0.013). Tumor board access (OR 2, CI 1.00-4.02; P = 0.051) was borderline significant. Non-clinical patient factors play a role in medical oncologist decision-making for breast cancer adjuvant chemotherapy recommendations.

  10. Organizational attributes that assure optimal utilization of public health nurses.

    PubMed

    Meagher-Stewart, Donna; Underwood, Jane; MacDonald, Mary; Schoenfeld, Bonnie; Blythe, Jennifer; Knibbs, Kristin; Munroe, Val; Lavoie-Tremblay, Mélanie; Ehrlich, Anne; Ganann, Rebecca; Crea, Mary

    2010-01-01

    Optimal utilization of public health nurses (PHNs) is important for strengthening public health capacity and sustaining interest in public health nursing in the face of a global nursing shortage. To gain an insight into the organizational attributes that support PHNs to work effectively, 23 focus groups were held with PHNs, managers, and policymakers in diverse regions and urban and rural/remote settings across Canada. Participants identified attributes at all levels of the public health system: government and system-level action, local organizational culture of their employers, and supportive management practices. Effective leadership emerged as a strong message throughout all levels. Other organizational attributes included valuing and promoting public health nursing; having a shared vision, goals, and planning; building partnerships and collaboration; demonstrating flexibility and creativity; and supporting ongoing learning and knowledge sharing. The results of this study highlight opportunities for fostering organizational development and leadership in public health, influencing policies and programs to optimize public health nursing services and resources, and supporting PHNs to realize the full scope of their competencies.

  11. Viewpoints about collaboration between primary care and public health in Canada

    PubMed Central

    2013-01-01

    Background Although there is a global movement toward health system integration and collaboration, little is known about values, beliefs, and attitudes towards collaboration between stakeholders in public health (i.e. promotion, protection, and prevention with vulnerable groups and/or at the population level) and primary care (i.e., family practices, nurse-led clinics). The purpose of this study was to explore viewpoints of key stakeholders regarding primary care (PC) and public health (PH) collaboration in Canada. Methods We used Q-methodology to identify common viewpoints held by participants who attended a national meeting in Canada in 2010 to discuss PC and PH collaboration. The study was conducted in two phases. In Phase 1 a Q-sample, a Q-sort table, and a short demographic questionnaire were developed which were used in Phase 2 for data collection. The Q-sorts then were analysed to identify the salient factors and consensus statements. Results In total, 25 multidisciplinary individuals including researchers, policy-makers, directors, managers, and practitioners (e.g., nurses, family physicians, dietitians) participated. Using a by-person factor analysis, three factors (salient viewpoints) emerged. Factors were named based on their distinguishing statements as follows: a) System Driven Collaborators, b) Cautious Collaborators, and c) Competent Isolationists. System Driven Collaborators strongly believed that a clear mandate from the top is needed to enable PH, PC and the rest of the health system to effectively work together and that people in different branches in the Ministry/ Ministries have to strongly believe in collaboration, actively support it, and develop directed policies to foster organizations work together. Cautious Collaborators strongly supported the idea of having better consciousness-raising about what collaborations might be possible and beneficial, and also reflecting on the collaborations already in place. The Competent Isolationists strongly believed that it is necessary for PC and PH sectors to spend time to ensure that both parties clearly understand the differences between their roles. They believe that physicians, nurses, and social workers will not see the value in collaboration because they lack inter-professional educational programs. Conclusions Different viewpoints are held by stakeholders around PC and PH collaboration which have the potential to influence the success of collaborations. Understanding and managing these differences is important to assist change management processes required to build and maintain strong PC and PH collaborations. PMID:23945461

  12. Location-based technologies for supporting elderly pedestrian in "getting lost" events.

    PubMed

    Pulido Herrera, Edith

    2017-05-01

    Localization-based technologies promise to keep older adults with dementia safe and support them and their caregivers during getting lost events. This paper summarizes mainly technological contributions to support the target group in these events. Moreover, important aspects of the getting lost phenomenon such as its concept and ethical issues are also briefly addressed. Papers were selected from scientific databases and gray literature. Since the topic is still in its infancy, other terms were used to find contributions associated with getting lost e.g. wandering. Trends of applying localization systems were identified as personal locators, perimeter systems and assistance systems. The first system barely considered the older adult's opinion, while assistance systems may involve context awareness to improve the support for both the elderly and the caregiver. Since few studies report multidisciplinary work with a special focus on getting lost, there is not a strong evidence of the real efficiency of localization systems or guidelines to design systems for the target group. Further research about getting lost is required to obtain insights for developing customizable systems. Moreover, considering conditions of the older adult might increase the impact of developments that combine localization technologies and artificial intelligence techniques. Implications for Rehabilitation Whilst there is no cure for dementia such as Alzheimer's, it is feasible to take advantage of technological developments to somewhat diminish its negative impact. For instance, location-based systems may provide information to early diagnose the Alzheimer's disease by assessing navigational impairments of older adults. Assessing the latest supportive technologies and methodologies may provide insights to adopt strategies to properly manage getting lost events. More user-centered designs will provide appropriate assistance to older adults. Namely, customizable systems could assist older adults in their daily walks with the aim to increase their self-confidence, independence and autonomy.

  13. The merit of meritocracy.

    PubMed

    Son Hing, Leanne S; Bobocel, D Ramona; Zanna, Mark P; Garcia, Donna M; Gee, Stephanie S; Orazietti, Katie

    2011-09-01

    We argue that the preference for the merit principle is a separate construct from hierarchy-legitimizing ideologies (i.e., system justification beliefs, prejudice, social dominance orientation), including descriptive beliefs that meritocracy currently exists in society. Moreover, we hypothesized that prescriptive beliefs about merit should have a stronger influence on reactions to the status quo when hierarchy-legitimizing ideologies are weak (vs. strong). In 4 studies, participants' preference for the merit principle and hierarchy-legitimizing ideologies were assessed; later, the participants evaluated organizational selection practices that support or challenge the status quo. Participants' prescriptive and descriptive beliefs about merit were separate constructs; only the latter predicted other hierarchy-legitimizing ideologies. In addition, as hypothesized, among participants who weakly endorsed hierarchy-legitimizing ideologies, the stronger their preference for the merit principle, the more they opposed selection practices that were perceived to be merit violating but the more they supported practices that were perceived to be merit restoring. In contrast, those who strongly endorsed hierarchy-legitimizing ideologies were always motivated to support the status quo, regardless of their preference for the merit principle. PsycINFO Database Record (c) 2011 APA, all rights reserved.

  14. Evidence for a New Intermediate Phase in a Strongly Correlated 2D System near Wigner Crystallization

    NASA Astrophysics Data System (ADS)

    Gao, Xuan; Qiu, Richard; Goble, Nicholas; Serafin, Alex; Yin, Liang; Xia, Jian-Sheng; Sullivan, Neil; Pfeiffer, Loren; West, Ken

    How the two dimensional (2D) quantum Wigner crystal (WC) transforms into the metallic liquid phase remains an outstanding problem in physics. In theories considering the 2D WC to liquid transition in the clean limit, it was suggested that a number of intermediate phases might exist. We have studied the transformation between the metallic fluid phase and the low magnetic field reentrant insulating phase (RIP) which was interpreted as due to the WC [Qiu et al., PRL 108, 106404 (2012)], in a strongly correlated 2D hole system in GaAs quantum well with large interaction parameter rs (~20-30) and high mobility. Instead of a sharp transition, we found that increasing density (or lowering rs) drives the RIP into a state where the incipient RIP coexists with Fermi liquid. This apparent mixture phase intermediate between Fermi liquid and WC also exhibits a non-trivial temperature dependent resistivity behavior which can be qualitatively understood by the reversed melting of WC in the mixture, in analogy to the Pomeranchuk effect in the solid-liquid mixture of Helium-3. X.G. thanks NSF (DMR-0906415) for supporting work at CWRU. Experiments at the NHMFL High B/T Facility were supported by NSF Grant 0654118 and the State of Florida. L.P. thanks the Gordon and Betty Moore Foundation and NSF MRSEC (DMR-0819860) for support.

  15. Usability evaluation of pharmacogenomics clinical decision support aids and clinical knowledge resources in a computerized provider order entry system: a mixed methods approach.

    PubMed

    Devine, Emily Beth; Lee, Chia-Ju; Overby, Casey L; Abernethy, Neil; McCune, Jeannine; Smith, Joe W; Tarczy-Hornoch, Peter

    2014-07-01

    Pharmacogenomics (PGx) is positioned to have a widespread impact on the practice of medicine, yet physician acceptance is low. The presentation of context-specific PGx information, in the form of clinical decision support (CDS) alerts embedded in a computerized provider order entry (CPOE) system, can aid uptake. Usability evaluations can inform optimal design, which, in turn, can spur adoption. The study objectives were to: (1) evaluate an early prototype, commercial CPOE system with PGx-CDS alerts in a simulated environment, (2) identify potential improvements to the system user interface, and (3) understand the contexts under which PGx knowledge embedded in an electronic health record is useful to prescribers. Using a mixed methods approach, we presented seven cardiologists and three oncologists with five hypothetical clinical case scenarios. Each scenario featured a drug for which a gene encoding drug metabolizing enzyme required consideration of dosage adjustment. We used Morae(®) to capture comments and on-screen movements as participants prescribed each drug. In addition to PGx-CDS alerts, 'Infobutton(®)' and 'Evidence' icons provided participants with clinical knowledge resources to aid decision-making. Nine themes emerged. Five suggested minor improvements to the CPOE user interface; two suggested presenting PGx information through PGx-CDS alerts using an 'Infobutton' or 'Evidence' icon. The remaining themes were strong recommendations to provide succinct, relevant guidelines and dosing recommendations of phenotypic information from credible and trustworthy sources; any more information was overwhelming. Participants' median rating of PGx-CDS system usability was 2 on a Likert scale ranging from 1 (strongly agree) to 7 (strongly disagree). Usability evaluation results suggest that participants considered PGx information important for improving prescribing decisions; and that they would incorporate PGx-CDS when information is presented in relevant and useful ways. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  16. Leadership Perspectives on Operationalizing the Learning Health Care System in an Integrated Delivery System

    PubMed Central

    Psek, Wayne; Davis, F. Daniel; Gerrity, Gloria; Stametz, Rebecca; Bailey-Davis, Lisa; Henninger, Debra; Sellers, Dorothy; Darer, Jonathan

    2016-01-01

    Introduction: Healthcare leaders need operational strategies that support organizational learning for continued improvement and value generation. The learning health system (LHS) model may provide leaders with such strategies; however, little is known about leaders’ perspectives on the value and application of system-wide operationalization of the LHS model. The objective of this project was to solicit and analyze senior health system leaders’ perspectives on the LHS and learning activities in an integrated delivery system. Methods: A series of interviews were conducted with 41 system leaders from a broad range of clinical and administrative areas across an integrated delivery system. Leaders’ responses were categorized into themes. Findings: Ten major themes emerged from our conversations with leaders. While leaders generally expressed support for the concept of the LHS and enhanced system-wide learning, their concerns and suggestions for operationalization where strongly aligned with their functional area and strategic goals. Discussion: Our findings suggests that leaders tend to adopt a very pragmatic approach to learning. Leaders expressed a dichotomy between the operational imperative to execute operational objectives efficiently and the need for rigorous evaluation. Alignment of learning activities with system-wide strategic and operational priorities is important to gain leadership support and resources. Practical approaches to addressing opportunities and challenges identified in the themes are discussed. Conclusion: Continuous learning is an ongoing, multi-disciplinary function of a health care delivery system. Findings from this and other research may be used to inform and prioritize system-wide learning objectives and strategies which support reliable, high value care delivery. PMID:27683668

  17. Health Belief Systems and the Psychobiology of War

    PubMed Central

    Elgee, Neil J.

    1984-01-01

    Belief systems overlie powerful biological and psychological forces that are root causes of war. Much as in medicine where an appreciation of health belief systems is necessary in the control of illness and disease, so the paths to the control of war may lie in an understanding of belief systems and ways to circumvent them. Such understanding gives strong theoretical support to many time-honored but underutilized international initiative and educational ventures. The effort of the medical community to educate the public about biomedical aspects of nuclear war should gain more balance and sophistication with an appreciation of belief systems in the psychobiology of war. PMID:6741137

  18. A Multi-mission Event-Driven Component-Based System for Support of Flight Software Development, ATLO, and Operations first used by the Mars Science Laboratory (MSL) Project

    NASA Technical Reports Server (NTRS)

    Dehghani, Navid; Tankenson, Michael

    2006-01-01

    This viewgraph presentation reviews the architectural description of the Mission Data Processing and Control System (MPCS). MPCS is an event-driven, multi-mission ground data processing components providing uplink, downlink, and data management capabilities which will support the Mars Science Laboratory (MSL) project as its first target mission. MPCS is designed with these factors (1) Enabling plug and play architecture (2) MPCS has strong inheritance from GDS components that have been developed for other Flight Projects (MER, MRO, DAWN, MSAP), and are currently being used in operations and ATLO, and (3) MPCS components are Java-based, platform independent, and are designed to consume and produce XML-formatted data

  19. CMMAD Usability Case Study in Support of Countermine and Hazard Sensing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Victor G. Walker; David I. Gertman

    2010-04-01

    During field trials, operator usability data were collected in support of lane clearing missions and hazard sensing for two robot platforms with Robot Intelligence Kernel (RIK) software and sensor scanning payloads onboard. The tests featured autonomous and shared robot autonomy levels where tasking of the robot used a graphical interface featuring mine location and sensor readings. The goal of this work was to provide insights that could be used to further technology development. The efficacy of countermine systems in terms of mobility, search, path planning, detection, and localization were assessed. Findings from objective and subjective operator interaction measures are reviewedmore » along with commentary from soldiers having taken part in the study who strongly endorse the system.« less

  20. Bloch oscillations in the absence of a lattice

    NASA Astrophysics Data System (ADS)

    Meinert, Florian; Knap, Michael; Kirilov, Emil; Jag-Lauber, Katharina; Zvonarev, Mikhail B.; Demler, Eugene; Nägerl, Hanns-Christoph

    2017-06-01

    The interplay of strong quantum correlations and far-from-equilibrium conditions can give rise to striking dynamical phenomena. We experimentally investigated the quantum motion of an impurity atom immersed in a strongly interacting one-dimensional Bose liquid and subject to an external force. We found that the momentum distribution of the impurity exhibits characteristic Bragg reflections at the edge of an emergent Brillouin zone. Although Bragg reflections are typically associated with lattice structures, in our strongly correlated quantum liquid they result from the interplay of short-range crystalline order and kinematic constraints on the many-body scattering processes in the one-dimensional system. As a consequence, the impurity exhibits periodic dynamics, reminiscent of Bloch oscillations, although the quantum liquid is translationally invariant. Our observations are supported by large-scale numerical simulations.

  1. Neurodevelopment, GABA System Dysfunction, and Schizophrenia

    PubMed Central

    Schmidt, Martin J; Mirnics, Karoly

    2015-01-01

    The origins of schizophrenia have eluded clinicians and researchers since Kraepelin and Bleuler began documenting their findings. However, large clinical research efforts in recent decades have identified numerous genetic and environmental risk factors for schizophrenia. The combined data strongly support the neurodevelopmental hypothesis of schizophrenia and underscore the importance of the common converging effects of diverse insults. In this review, we discuss the evidence that genetic and environmental risk factors that predispose to schizophrenia disrupt the development and normal functioning of the GABAergic system. PMID:24759129

  2. Integration for navigation on the UMASS mobile perception lab

    NASA Technical Reports Server (NTRS)

    Draper, Bruce; Fennema, Claude; Rochwerger, Benny; Riseman, Edward; Hanson, Allen

    1994-01-01

    Integration of real-time visual procedures for use on the Mobile Perception Lab (MPL) was presented. The MPL is an autonomous vehicle designed for testing visually guided behavior. Two critical areas of focus in the system design were data storage/exchange and process control. The Intermediate Symbolic Representation (ISR3) supported data storage and exchange, and the MPL script monitor provided process control. Resource allocation, inter-process communication, and real-time control are difficult problems which must be solved in order to construct strong autonomous systems.

  3. Neurodevelopment, GABA system dysfunction, and schizophrenia.

    PubMed

    Schmidt, Martin J; Mirnics, Karoly

    2015-01-01

    The origins of schizophrenia have eluded clinicians and researchers since Kraepelin and Bleuler began documenting their findings. However, large clinical research efforts in recent decades have identified numerous genetic and environmental risk factors for schizophrenia. The combined data strongly support the neurodevelopmental hypothesis of schizophrenia and underscore the importance of the common converging effects of diverse insults. In this review, we discuss the evidence that genetic and environmental risk factors that predispose to schizophrenia disrupt the development and normal functioning of the GABAergic system.

  4. The failure of AHERF: 5 important lessons.

    PubMed

    Goldstein, Lisa

    2008-08-01

    Important lessons from AHERF's downfall: Strong governance and oversight of management are needed to ensure accountability; Disciplined growth strategies need to be supported by rigorous financial planning and feasibility analysis; Physician integration is critical to grow market share, but needs to be methodical and measured; Robust information systems are necessary to manage costs, maximize revenue, and provide differentiation in quality and clinical outcomes; Disclosure of the financial performance of all of a health system's operations creates greater transparency and builds credibility.

  5. Integrating Continuing Professional Development With Health System Reform: Building Pillars of Support.

    PubMed

    Davis, David A; Rayburn, William F

    2016-01-01

    Clinical failures sparked a widespread desire for health system reform at the beginning of the 21st century, but related efforts have resulted in changes that are either slow or nonexistent. In response, academic medicine has moved in two directions: (1) system-wide reform using electronic health records, practice networks, and widespread data applications (a macro pathway); and (2) professional development of individual clinicians through continuous performance improvement (a micro pathway). Both pathways exist to improve patient care and population health, yet each suffers from limitations in widespread implementation. The authors call for a better union between these two parallel pathways through four pillars of support: (1) an acknowledgment that both pathways are essential to each other and to the final outcome they intend to achieve, (2) a strong faculty commitment to educate about quality improvement and patient safety at all education levels, (3) a reengineering of tools for professional development to serve as effective change agents, and (4) the development of standards to sustain this alignment of pathways. With these pillars of support integrating continuing professional development with health system reform, the authors envision a better functioning system, with improved metrics and value to enhance patient care and population health.

  6. An adaptive compensation algorithm for temperature drift of micro-electro-mechanical systems gyroscopes using a strong tracking Kalman filter.

    PubMed

    Feng, Yibo; Li, Xisheng; Zhang, Xiaojuan

    2015-05-13

    We present an adaptive algorithm for a system integrated with micro-electro-mechanical systems (MEMS) gyroscopes and a compass to eliminate the influence from the environment, compensate the temperature drift precisely, and improve the accuracy of the MEMS gyroscope. We use a simplified drift model and changing but appropriate model parameters to implement this algorithm. The model of MEMS gyroscope temperature drift is constructed mostly on the basis of the temperature sensitivity of the gyroscope. As the state variables of a strong tracking Kalman filter (STKF), the parameters of the temperature drift model can be calculated to adapt to the environment under the support of the compass. These parameters change intelligently with the environment to maintain the precision of the MEMS gyroscope in the changing temperature. The heading error is less than 0.6° in the static temperature experiment, and also is kept in the range from 5° to -2° in the dynamic outdoor experiment. This demonstrates that the proposed algorithm exhibits strong adaptability to a changing temperature, and performs significantly better than KF and MLR to compensate the temperature drift of a gyroscope and eliminate the influence of temperature variation.

  7. Anomalous Thermal Diffusivity in Bad Metals

    NASA Astrophysics Data System (ADS)

    Zhang, Jiecheng; Levenson-Falk, Eli M.; Ramshaw, Brad J.; Bonn, Douglas A.; Liang, Ruixing; Hardy, Walter N.; Hartnoll, Sean A.; Kapitulnik, Aharon

    Local measurements of thermal diffusivity are used to analyze the transport of heat in the bad metallic regime of several strongly correlated materials. In underdoped YBCO systems, we use the in-plane anisotropy to analyze transport in this system. Specifically, we find that the diffusivity anisotropy is comparable to reported values of the electrical resistivity anisotropy and drops sharply below the charge order transition, suggesting that both anisotropies have the same origin. We interpret our results through a strong electron-phonon scattering picture and find that both electronic and phononic contributions to the diffusivity exhibit a saturated scattering time of ℏ /kB T . Our results suggest that neither well-defined electron nor phonon quasiparticles are present in underdoped YBCO systems, and thermal transport exhibits a collective behavior of a ''soup'' of strongly coupled electrons and phonons which moves at a velocity that is smaller than the Fermi velocity, but larger than the speed of sound. We generalize this treatment to measurements of other bad metals and discuss its implications. Work supported by the Gordon and Betty Moore Foundation through the EPiQS Initiative, Grant GBMF4529, and by a Department of Energy Early Career Award (SAH).

  8. Driven superconducting quantum circuits

    NASA Astrophysics Data System (ADS)

    Nakamura, Yasunobu

    2014-03-01

    Driven nonlinear quantum systems show rich phenomena in various fields of physics. Among them, superconducting quantum circuits have very attractive features such as well-controlled quantum states with design flexibility, strong nonlinearity of Josephson junctions, strong coupling to electromagnetic driving fields, little internal dissipation, and tailored coupling to the electromagnetic environment. We have investigated properties and functionalities of driven superconducting quantum circuits. A transmon qubit coupled to a transmission line shows nearly perfect spatial mode matching between the incident and scattered microwave field in the 1D mode. Dressed states under a driving field are studied there and also in a semi-infinite 1D mode terminated by a resonator containing a flux qubit. An effective Λ-type three-level system is realized under an appropriate driving condition. It allows ``impedance-matched'' perfect absorption of incident probe photons and down conversion into another frequency mode. Finally, the weak signal from the qubit is read out using a Josephson parametric amplifier/oscillator which is another nonlinear circuit driven by a strong pump field. This work was partly supported by the Funding Program for World-Leading Innovative R&D on Science and Technology (FIRST), Project for Developing Innovation Systems of MEXT, MEXT KAKENHI ``Quantum Cybernetics,'' and the NICT Commissioned Research.

  9. Adsorbate-mediated strong metal–support interactions in oxide-supported Rh catalysts

    DOE PAGES

    Matsubu, John C.; Zhang, Shuyi; DeRita, Leo; ...

    2016-09-19

    The optimization of supported metal catalysts predominantly focuses on engineering the metal site, for which physical insights based on extensive theoretical and experimental contributions have enabled the rational design of active sites. Although it is well known that supports can influence the catalytic properties of metals, insights into how metal–support interactions can be exploited to optimize metal active-site properties are lacking. Here in this paper, we utilize in situ spectroscopy and microscopy to identify and characterize a support effect in oxide-supported heterogeneous Rh catalysts. This effect is characterized by strongly bound adsorbates (HCO x) on reducible oxide supports (TiO 2more » and Nb 2O 5) that induce oxygen-vacancy formation in the support and cause HCO x-functionalized encapsulation of Rh nanoparticles by the support. The encapsulation layer is permeable to reactants, stable under the reaction conditions and strongly influences the catalytic properties of Rh, which enables rational and dynamic tuning of CO 2-reduction selectivity.« less

  10. Flight Dynamics Mission Support and Quality Assurance Process

    NASA Technical Reports Server (NTRS)

    Oh, InHwan

    1996-01-01

    This paper summarizes the method of the Computer Sciences Corporation Flight Dynamics Operation (FDO) quality assurance approach to support the National Aeronautics and Space Administration Goddard Space Flight Center Flight Dynamics Support Branch. Historically, a strong need has existed for developing systematic quality assurance using methods that account for the unique nature and environment of satellite Flight Dynamics mission support. Over the past few years FDO has developed and implemented proactive quality assurance processes applied to each of the six phases of the Flight Dynamics mission support life cycle: systems and operations concept, system requirements and specifications, software development support, operations planing and training, launch support, and on-orbit mission operations. Rather than performing quality assurance as a final step after work is completed, quality assurance has been built in as work progresses in the form of process assurance. Process assurance activities occur throughout the Flight Dynamics mission support life cycle. The FDO Product Assurance Office developed process checklists for prephase process reviews, mission team orientations, in-progress reviews, and end-of-phase audits. This paper will outline the evolving history of FDO quality assurance approaches, discuss the tailoring of Computer Science Corporations's process assurance cycle procedures, describe some of the quality assurance approaches that have been or are being developed, and present some of the successful results.

  11. Opportunities for strengthening infant and young child feeding policies in South Asia: Insights from the SAIFRN policy analysis project.

    PubMed

    Thow, Anne Marie; Karn, Sumit; Devkota, Madhu Dixit; Rasheed, Sabrina; Roy, S K; Suleman, Yasmeen; Hazir, Tabish; Patel, Archana; Gaidhane, Abhay; Puri, Seema; Godakandage, Sanjeeva; Senarath, Upul; Dibley, Michael J

    2017-06-13

    South Asian countries experience some of the highest levels of child undernutrition in the world, strongly linked to poor infant and young child feeding (IYCF) practices. Strong and responsive policy support is essential for effective interventions to improve IYCF. This study aimed to identify opportunities for strengthening the policy environment in the region to better support appropriate infant and young child feeding. We mapped policies relevant to infant and young child feeding in India, Pakistan, Bangladesh, Sri Lanka and Nepal, based on a common matrix. The matrix described potentially relevant policies ranging from high-level strategic policy documents to implementation-level guidelines. We analyzed the data based on themes focused on caregiver interactions with IYCF interventions: provision of correct information to mothers, training of frontline workers, enabling mothers to engage with service providers and strategic support for IYCF. Policy support for IYCF was present in relation to each of the themes assessed. In all countries, there was support for nutrition in National Development Plans, and all countries had some level of maternity protection and restrictions on marketing of breast milk substitutes. Sectoral and implementation-level policy documents contained provisions for system strengthening for IYCF and for training of frontline workers. The key opportunities for strengthening IYCF policy support were in relation to translating strategic directives into implementation level documents; improving multi-sectoral support and coordination; and increased clarity regarding roles and responsibilities of frontline workers interacting with mothers. These findings can support efforts to strengthen IYCF policy at the national and regional level.

  12. The Effects of Concept Map-Oriented Gesture-Based Teaching System on Learners' Learning Performance and Cognitive Load in Earth Science Course

    ERIC Educational Resources Information Center

    Hsieh, Sheng-Wen; Ho, Shu-Chun; Wu, Min-ping; Ni, Ci-Yuan

    2016-01-01

    Gesture-based learning have particularities, because learners interact in the learning process through the actual way, just like they interact in the nondigital world. It also can support kinesthetic pedagogical practices to benefit learners with strong bodily-kinesthetic intelligence. But without proper assistance or guidance, learners' learning…

  13. 77 FR 21663 - Air Quality Implementation Plans; Kentucky; Attainment Plan for the Kentucky Portion of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-11

    ... available, but not yet certified, in the Air Quality System (AQS) database for 2011 show that this Area.... Moreover, there is no support for the Commenter's contention, based on the flawed premise that allowance... strong legal basis. To the extent that the current status of CAIR and the Transport Rule affect any of...

  14. A Grant Project to Initiate School Counselors' Development of a Multi-Tiered System of Supports Based on Social-Emotional Data

    ERIC Educational Resources Information Center

    Harrington, Karen; Griffith, Catherine; Gray, Katharine; Greenspan, Scott

    2016-01-01

    This article provides an overview of a grant project designed to create a district-wide elementary school counseling program with a strong data-based decision-making process. Project goals included building data literacy skills among school counselors and developing the infrastructure to efficiently collect important social-emotional indicators…

  15. Investing in Education Powers U.S. Competitiveness: Education Funding Must Be Preserved

    ERIC Educational Resources Information Center

    Epstein, Diana

    2012-01-01

    Education is the key to American competitiveness and a strong economy, and continued federal investment in education is needed in order to support improvements in student achievement and put American economy on the path to sustained growth. The United States must continue to invest in education in order to create a system that is more equitable…

  16. Now that the Baby Boomers Are Middle-Aged...Threats, Challenges and Opportunities of the 21st Century. Perspectives.

    ERIC Educational Resources Information Center

    Glossop, Robert

    Canadian baby-boomers will reach old age around 2020. Until then, they represent a large, well-educated generation whose economic productivity provides a strong base on which to build the necessary systems of income support, health and social service delivery, and economic adjustment that will be required to age gracefully. Canadians can expect…

  17. Financial Strategies to Support Citywide Systems of Out-of-School Time Programs. Strategy Guide

    ERIC Educational Resources Information Center

    Russell, Lane

    2009-01-01

    With most parents now in the workforce, the demand for high-quality out-of-school time (OST) opportunities for children and youth continues to grow across the country. An estimated 14.3 million children and youth return each day to an empty home unsupervised, and with no opportunities to constructively occupy their time. By building strong,…

  18. A Large-Scale, Higher-Level, Molecular Phylogenetic Study of the Insect Order Lepidoptera (Moths and Butterflies)

    PubMed Central

    Regier, Jerome C.; Mitter, Charles; Zwick, Andreas; Bazinet, Adam L.; Cummings, Michael P.; Kawahara, Akito Y.; Sohn, Jae-Cheon; Zwickl, Derrick J.; Cho, Soowon; Davis, Donald R.; Baixeras, Joaquin; Brown, John; Parr, Cynthia; Weller, Susan; Lees, David C.; Mitter, Kim T.

    2013-01-01

    Background Higher-level relationships within the Lepidoptera, and particularly within the species-rich subclade Ditrysia, are generally not well understood, although recent studies have yielded progress. We present the most comprehensive molecular analysis of lepidopteran phylogeny to date, focusing on relationships among superfamilies. Methodology / Principal Findings 483 taxa spanning 115 of 124 families were sampled for 19 protein-coding nuclear genes, from which maximum likelihood tree estimates and bootstrap percentages were obtained using GARLI. Assessment of heuristic search effectiveness showed that better trees and higher bootstrap percentages probably remain to be discovered even after 1000 or more search replicates, but further search proved impractical even with grid computing. Other analyses explored the effects of sampling nonsynonymous change only versus partitioned and unpartitioned total nucleotide change; deletion of rogue taxa; and compositional heterogeneity. Relationships among the non-ditrysian lineages previously inferred from morphology were largely confirmed, plus some new ones, with strong support. Robust support was also found for divergences among non-apoditrysian lineages of Ditrysia, but only rarely so within Apoditrysia. Paraphyly for Tineoidea is strongly supported by analysis of nonsynonymous-only signal; conflicting, strong support for tineoid monophyly when synonymous signal was added back is shown to result from compositional heterogeneity. Conclusions / Significance Support for among-superfamily relationships outside the Apoditrysia is now generally strong. Comparable support is mostly lacking within Apoditrysia, but dramatically increased bootstrap percentages for some nodes after rogue taxon removal, and concordance with other evidence, strongly suggest that our picture of apoditrysian phylogeny is approximately correct. This study highlights the challenge of finding optimal topologies when analyzing hundreds of taxa. It also shows that some nodes get strong support only when analysis is restricted to nonsynonymous change, while total change is necessary for strong support of others. Thus, multiple types of analyses will be necessary to fully resolve lepidopteran phylogeny. PMID:23554903

  19. New Circuit QED system based on Triple-leg Stripline Resonator.

    NASA Astrophysics Data System (ADS)

    Kim, Dongmin; Moon, Kyungsun

    Conventional circuit QED system consists of a qubit located inside a linear stripline resonator, which has successfully demonstrated a strong coupling between a single photon and a qubit. Here we present a new circuit QED system, where the qubit is coupled to triple-leg stripline resonator (TSR). We have shown that TSR supports two-fold degenerate photon modes among others. By coupling them to a single qubit, we have obtained the dressed states of a coupled system of a single qubit and two-fold degenerate photon modes. By locating two qubits at two legs of TSR, we have studied a potential two-bit gate operation (e.g., CNOT gate) of the system. We will discuss the main advantage of utilizing two-fold degenerate photon modes This work is partially supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (NRF-2016R1D1A1B01013756).

  20. Participatory research to design a novel telehealth system to support the night-time needs of people with dementia: NOCTURNAL.

    PubMed

    Martin, Suzanne; Augusto, Juan Carlos; McCullagh, Paul; Carswell, William; Zheng, Huiru; Wang, Haiying; Wallace, Jonathan; Mulvenna, Maurice

    2013-12-04

    Strategies to support people living with dementia are broad in scope, proposing both pharmacological and non-pharmacological interventions as part of the care pathway. Assistive technologies form part of this offering as both stand-alone devices to support particular tasks and the more complex offering of the "smart home" to underpin ambient assisted living. This paper presents a technology-based system, which expands on the smart home architecture, orientated to support people with daily living. The system, NOCTURNAL, was developed by working directly with people who had dementia, and their carers using qualitative research methods. The research focused primarily on the nighttime needs of people living with dementia in real home settings. Eight people with dementia had the final prototype system installed for a three month evaluation at home. Disturbed sleep patterns, night-time wandering were a focus of this research not only in terms of detection by commercially available technology but also exploring if automated music, light and visual personalized photographs would be soothing to participants during the hours of darkness. The NOCTURNAL platform and associated services was informed by strong user engagement of people with dementia and the service providers who care for them. NOCTURNAL emerged as a holistic service offering a personalised therapeutic aspect with interactive capabilities.

  1. Predictors of Healthcare System and Physician Distrust In Hospitalized Cardiac Patients

    PubMed Central

    Gupta, Charu; Bell, Susan P.; Schildcrout, Jonathan S.; Fletcher, Sarah; Goggins, Kathryn M.; Kripalani, Sunil

    2015-01-01

    A trusting relationship between patients, physicians, and the healthcare system is important in encouraging self-care behaviors in cardiovascular patients. The study aimed to assess the prevalence of healthcare system and physician distrust in this population, compare the two forms of distrust, and describe the demographic, socioeconomic, and psycho-social predictors of high distrust. 1232 hospitalized adults with acute coronary syndrome or heart failure were enrolled in a prospective, observational study assessing both healthcare system and physician distrust. High healthcare system distrust (35%) was observed across the population, with lower levels of interpersonal physician distrust (16%). In a multivariate analysis, poor social support and coping skills were strong predictors of both healthcare system (p = 0.026, p = 0.003) and physician distrust (p <0.001, p = 0.006). Individuals with low or marginal health literacy had a higher likelihood of physician distrust (p <0.001), but no relationship was found between health literacy and healthcare system distrust. In conclusion, distrust is common among acutely ill cardiac patients. Those with low social support and low coping skills are more distrusting of physicians and the healthcare system. PMID:25315583

  2. Reliability Impacts in Life Support Architecture and Technology Selection

    NASA Technical Reports Server (NTRS)

    Lange, Kevin E.; Anderson, Molly S.

    2011-01-01

    Equivalent System Mass (ESM) and reliability estimates were performed for different life support architectures based primarily on International Space Station (ISS) technologies. The analysis was applied to a hypothetical 1-year deep-space mission. High-level fault trees were initially developed relating loss of life support functionality to the Loss of Crew (LOC) top event. System reliability was then expressed as the complement (nonoccurrence) this event and was increased through the addition of redundancy and spares, which added to the ESM. The reliability analysis assumed constant failure rates and used current projected values of the Mean Time Between Failures (MTBF) from an ISS database where available. Results were obtained showing the dependence of ESM on system reliability for each architecture. Although the analysis employed numerous simplifications and many of the input parameters are considered to have high uncertainty, the results strongly suggest that achieving necessary reliabilities for deep-space missions will add substantially to the life support system mass. As a point of reference, the reliability for a single-string architecture using the most regenerative combination of ISS technologies without unscheduled replacement spares was estimated to be less than 1%. The results also demonstrate how adding technologies in a serial manner to increase system closure forces the reliability of other life support technologies to increase in order to meet the system reliability requirement. This increase in reliability results in increased mass for multiple technologies through the need for additional spares. Alternative parallel architecture approaches and approaches with the potential to do more with less are discussed. The tall poles in life support ESM are also reexamined in light of estimated reliability impacts.

  3. Sustaining change: the imperative for patient access strategies.

    PubMed

    Glynn, Peter A R

    2006-01-01

    The paper by Trypuc, MacLeod and Hudson provides a timely and important overview of methods to sustain provincial wait time strategies. The emphasis on accountability for patient access to timely care throughout the healthcare system comes through strongly--as it should. These accountabilities are made "real" through purchase service agreements. Physician-hospital relationships are a fundamental aspect of this accountability. This commentary suggests the inclusion of two additional supporting tools in addition to those cited by the authors of the lead paper--quality monitoring and the use of industrial engineering techniques for queue management and patient flow analysis. Strong and persistent leadership of patient access strategies will ensure sustainable change.

  4. Phaeochromocytoma [corrected] crisis.

    PubMed

    Whitelaw, B C; Prague, J K; Mustafa, O G; Schulte, K-M; Hopkins, P A; Gilbert, J A; McGregor, A M; Aylwin, S J B

    2014-01-01

    Phaeochromocytoma [corrected] crisis is an endocrine emergency associated with significant mortality. There is little published guidance on the management of phaeochromocytoma [corrected] crisis. This clinical practice update summarizes the relevant published literature, including a detailed review of cases published in the past 5 years, and a proposed classification system. We review the recommended management of phaeochromocytoma [corrected] crisis including the use of alpha-blockade, which is strongly associated with survival of a crisis. Mechanical circulatory supportive therapy (including intra-aortic balloon pump or extra-corporeal membrane oxygenation) is strongly recommended for patients with sustained hypotension. Surgical intervention should be deferred until medical stabilization is achieved. © 2013 John Wiley & Sons Ltd.

  5. Rehabilitation is a way of thinking, not a way of doing.

    PubMed

    Wade, Derick T

    2002-09-01

    There is strong evidence that the processes used by rehabilitation services are effective at reducing mortality and morbidity, yet purchasers still feel that there is insufficient evidence to warrant buying rehabilitation. Why? Evidence in support of many individual treatments is either weak or absent, but it is important not to conflate evidence about the process with evidence about specific actions. The absence of evidence concerning specific interventions should not be interpreted as meaning that rehabilitation is ineffective, and should certainly not be used as an excuse not to purchase rehabilitation. The evidence strongly suggests that the whole system works and until we have further evidence, the system should be bought as a whole. Further research into specific interventions should continue, but in addition there should be more research attention paid to the rehabilitation process itself.

  6. Public views on the role of government in funding and delivering health services.

    PubMed

    Vilhjalmsson, Runar

    2016-07-01

    Public surveys in socialized health systems indicate strong support for the role of government in health care, although different views can be detected. The study considers the public's views on public versus private funding and delivery of health services. The study is based on a representative national sample of 1532 Icelandic adults, aged 18 and older, who participated in a national public issues survey. Respondents were asked about government spending on health care and whether the government or private parties should deliver health services. The great majority of respondents thought that the government should spend more on health care, and should be the primary provider of care. Lower age, female gender, countryside residence, and expected high use of health care were related to greater support for governmental funding. Furthermore, countryside residence, less education, lower income, not being a governmental health worker, expected high health care use, and left-wing political ideology were all related to greater support for governmental delivery of health care. CONCLUSIONS DESPITE SOCIODEMOGRAPHIC VARIATIONS, THE STUDY FINDS STRONG OVERALL SUPPORT FOR THE ROLE OF GOVERNMENT IN FUNDING AND DELIVERING HEALTH CARE PREVIOUS PERSPECTIVES AND HYPOTHESES OF WELFARE STATE ENDORSEMENT RECEIVED MIXED SUPPORT, SUGGESTING THAT FURTHER THEORETICAL AND EMPIRICAL WORK IS NEEDED TO BETTER ACCOUNT FOR PUBLIC VIEWS ON THE ROLE OF GOVERNMENT IN HEALTH CARE. © 2016 the Nordic Societies of Public Health.

  7. Using hardware-in-the-loop (HWIL) simulation to provide low-cost testing of TMD IR missile systems

    NASA Astrophysics Data System (ADS)

    Buford, James A., Jr.; Paone, Thad

    1998-07-01

    A greater awareness of and increased interest in the use of modeling and simulation (M&S) has been demonstrated at many levels within the Department of Defense (DoD) and all the Armed Services agencies in recent years. M&S application is regarded as a viable means of lowering the life cycle costs of theater missile defense (TMD) weapon system acquisition beginning with studies of new concepts of warfighting through user training and post-deployment support. The Missile Research, Engineering, and Development Center (MRDEC) of the U.S. Army Aviation and Missile Command (AMCOM) has an extensive history of applying all types of M&S to TMD weapon system development and has been a particularly strong advocate of hardware-in-the-loop (HWIL) simulation for many years. Over the past 10 years MRDEC has developed specific and dedicated HWIL capabilities for TMD applications in both the infrared and radio frequency sensor domains. This paper provides an overview of the infrared-based TMD HWIL missile facility known as the Imaging Infrared System Simulation (I2RSS) which is used to support the Theater High Altitude Air Defense (THAAD) missile system. This facility uses M&S to conduct daily THAAD HWIL missile simulations to support flight tests, missile/system development, independent verification and validation of weapon system embedded software and simulations, and missile/system performance against current and future threat environments. This paper describes the THAAD TMD HWIL role, process, major components, HWIL verification/validation, and daily HWIL support areas in terms of both missile and complete system.

  8. Transplant Image Processing Technology under Windows into the Platform Based on MiniGUI

    NASA Astrophysics Data System (ADS)

    Gan, Lan; Zhang, Xu; Lv, Wenya; Yu, Jia

    MFC has a large number of digital image processing-related API functions, object-oriented and class mechanisms which provides image processing technology strong support in Windows. But in embedded systems, image processing technology dues to the restrictions of hardware and software do not have the environment of MFC in Windows. Therefore, this paper draws on the experience of image processing technology of Windows and transplants it into MiniGUI embedded systems. The results show that MiniGUI/Embedded graphical user interface applications about image processing which used in embedded image processing system can be good results.

  9. Mach Cones in Viscous Matter

    NASA Astrophysics Data System (ADS)

    Bouras, I.; El, A.; Fochler, O.; Lauciello, F.; Reining, F.; Uphoff, J.; Wesp, C.; Molnar, E.; Niemi, H.; Xu, Z.; Greiner, C.

    2011-01-01

    Employing a microscopic transport model we investigate the evolution of high energetic jets moving through a viscous medium. For the scenario of an unstoppable jet we observe a clearly strong collective behavior for a low dissipative system η/s approx 0.005, leading to the observation of cone-like structures. Increasing the dissipation of the system to η/s approx 0.32 the Mach Cone structure vanishes. Furthermore, we investigate jet-associated particle correlations. A double-peak structure, as observed in experimental data, is even for low-dissipative systems not supported, because of the large influence of the head shock.

  10. Reliability Driven Space Logistics Demand Analysis

    NASA Technical Reports Server (NTRS)

    Knezevic, J.

    1995-01-01

    Accurate selection of the quantity of logistic support resources has a strong influence on mission success, system availability and the cost of ownership. At the same time the accurate prediction of these resources depends on the accurate prediction of the reliability measures of the items involved. This paper presents a method for the advanced and accurate calculation of the reliability measures of complex space systems which are the basis for the determination of the demands for logistics resources needed during the operational life or mission of space systems. The applicability of the method presented is demonstrated through several examples.

  11. Mobile impurities in ferromagnetic liquids

    NASA Astrophysics Data System (ADS)

    Kantian, Adrian; Schollwoeck, Ulrich; Giamarchi, Thierry

    2011-03-01

    Recent work has shown that mobile impurities in one dimensional interacting systems may exhibit behaviour that differs strongly from that predicted by standard Tomonaga-Luttinger liquid theory, with the appearance of power-law divergences in the spectral function signifying sublinear diffusion of the impurity. Using time-dependent matrix product states, we investigate a range of cases of mobile impurities in systems beyond the analytically accessible examples to assess the existence of a new universality class of low-energy physics in one-dimensional systems. Correspondence: Adrian.Kantian@unige.ch This work was supported in part by the Swiss SNF under MaNEP and division II.

  12. The self-organization and functional activity of binary system based on erucyl amidopropyl betaine - alkylated polyethyleneimine

    NASA Astrophysics Data System (ADS)

    Gaynanova, Gulnara A.; Valiakhmetova, Alsu R.; Kuryashov, Dmitry A.; Kudryashova, Yuliana R.; Lukashenko, Svetlana S.; Syakaev, Victor V.; Latypov, Shamil K.; Bukharov, Sergey V.; Bashkirtseva, Natalia Yu.; Zakharova, Lucia Ya.

    2013-11-01

    The self-organization in individual and binary aqueous solutions of a zwitterionic surfactant erucyl amidopropyl betaine and alkylated polyethyleneimine is carried out with a wide range of physical and chemical methods, including tensiometry, conductometry, dynamic light scattering, pH-metry, spectrophotometry, and fluorescence spectroscopy. The data obtained strongly support the formation of nanosized aggregates in the systems and provide information on their structure and probable morphological transitions. High solubilization capacity and data on the contact angle showed a possibility of the application of these systems as nanocontainers or oil wetting agents in the oil recovery.

  13. [The development of hospital medical supplies information management system].

    PubMed

    Cao, Shaoping; Gu, Hongqing; Zhang, Peng; Wang, Qiang

    2010-05-01

    The information management of medical materials by using high-tech computer, in order to improve the efficiency of the consumption of medical supplies, hospital supplies and develop a new technology way to manage the hospital and material support. Using C # NET, JAVA techniques to develop procedures for the establishment of hospital material management information system, set the various management modules, production of various statistical reports, standard operating procedures. The system is convenient, functional and strong, fluent statistical functions. It can always fully grasp and understand the whole hospital supplies run dynamic information, as a modern and effective tool for hospital materials management.

  14. On Critical Behaviour in Systems of Hamiltonian Partial Differential Equations.

    PubMed

    Dubrovin, Boris; Grava, Tamara; Klein, Christian; Moro, Antonio

    2015-01-01

    We study the critical behaviour of solutions to weakly dispersive Hamiltonian systems considered as perturbations of elliptic and hyperbolic systems of hydrodynamic type with two components. We argue that near the critical point of gradient catastrophe of the dispersionless system, the solutions to a suitable initial value problem for the perturbed equations are approximately described by particular solutions to the Painlevé-I (P[Formula: see text]) equation or its fourth-order analogue P[Formula: see text]. As concrete examples, we discuss nonlinear Schrödinger equations in the semiclassical limit. A numerical study of these cases provides strong evidence in support of the conjecture.

  15. Fuzzy cognitive maps for issue identification in a water resources conflict resolution system

    NASA Astrophysics Data System (ADS)

    Giordano, R.; Passarella, G.; Uricchio, V. F.; Vurro, M.

    In water management, conflicts of interests are inevitable due to the variety in quality demands and the number of stakeholders, which are affected in different ways by decisions concerning the use of the resources. Ignoring the differences among interests involved in water resources management and not resolving the emerging conflicts could lead to controversial strategies. In such cases, proposed solutions could generate strong opposition, making these solutions unfeasible. In our contribution, a Community Decision Support System is proposed. Such a system is able to support discussion and collaboration. The system helps participants to structure their problem, to help them learn about possible alternatives, their constraints and implications and to support the participants in the specification of their own preferences. More in detail, the proposed system helps each user in representing and communicating problem perspectives. To reach this aim, cognitive maps are used to capture parts of the stakeholders’ point of view and to enhance negotiation among individuals and organizations. The aim of the negotiation process is to define a shared cognitive map with regard to water management problems. Such a map can be called a water community cognitive map. The system performance has been tested by simulating a real conflict on water resources management that occurred some years ago in a river basin in the south of Italy.

  16. Extraordinary absorption of sound in porous lamella-crystals.

    PubMed

    Christensen, J; Romero-García, V; Picó, R; Cebrecos, A; de Abajo, F J García; Mortensen, N A; Willatzen, M; Sánchez-Morcillo, V J

    2014-04-14

    We present the design of a structured material supporting complete absorption of sound with a broadband response and functional for any direction of incident radiation. The structure which is fabricated out of porous lamellas is arranged into a low-density crystal and backed by a reflecting support. Experimental measurements show that strong all-angle sound absorption with almost zero reflectance takes place for a frequency range exceeding two octaves. We demonstrate that lowering the crystal filling fraction increases the wave interaction time and is responsible for the enhancement of intrinsic material dissipation, making the system more absorptive with less material.

  17. Extraordinary absorption of sound in porous lamella-crystals

    PubMed Central

    Christensen, J.; Romero-García, V.; Picó, R.; Cebrecos, A.; de Abajo, F. J. García; Mortensen, N. A.; Willatzen, M.; Sánchez-Morcillo, V. J.

    2014-01-01

    We present the design of a structured material supporting complete absorption of sound with a broadband response and functional for any direction of incident radiation. The structure which is fabricated out of porous lamellas is arranged into a low-density crystal and backed by a reflecting support. Experimental measurements show that strong all-angle sound absorption with almost zero reflectance takes place for a frequency range exceeding two octaves. We demonstrate that lowering the crystal filling fraction increases the wave interaction time and is responsible for the enhancement of intrinsic material dissipation, making the system more absorptive with less material. PMID:24728322

  18. A Discovery of Strong Metal–Support Bonding in Nanoengineered Au–Fe 3 O 4 Dumbbell-like Nanoparticles by in Situ Transmission Electron Microscopy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Han, Chang Wan; Choksi, Tej; Milligan, Cory

    The strength of metal-support bonding in heterogeneous catalysts determines their thermal stability, therefore, a tremendous amount of effort has been expended to understand metal-support interactions. Herein, we report the discovery of an anomalous “strong metal-support bonding” between gold nanoparticles and “nano-engineered” Fe 3O 4 substrates by in-situ microscopy. During in-situ vacuum annealing of Au-Fe 3O 4 dumbbell-like nanoparticles, synthesized by the epitaxial growth of nano-Fe 3O 4 on Au nanoparticles, the gold nanoparticles transform into the monolayered gold thinfilms and wet the surface of nano-Fe 3O 4, as the surface reduction of nano-Fe 3O 4 proceeds. This phenomenon results frommore » a unique coupling of the size-and shape-dependent high surface reducibility of nano-Fe 3O 4 and the extremely strong adhesion between Au and the reduced Fe 3O 4. This strong-metal support bonding reveals the significance of controlling the metal oxide support size and morphology for optimizing metal-support bonding and, ultimately, for the development of improved catalysts and functional nanostructures.« less

  19. A Discovery of Strong Metal-Support Bonding in Nanoengineered Au-Fe3O4 Dumbbell-like Nanoparticles by in Situ Transmission Electron Microscopy.

    PubMed

    Han, Chang Wan; Choksi, Tej; Milligan, Cory; Majumdar, Paulami; Manto, Michael; Cui, Yanran; Sang, Xiahan; Unocic, Raymond R; Zemlyanov, Dmitry; Wang, Chao; Ribeiro, Fabio H; Greeley, Jeffrey; Ortalan, Volkan

    2017-08-09

    The strength of metal-support bonding in heterogeneous catalysts determines their thermal stability, therefore, a tremendous amount of effort has been expended to understand metal-support interactions. Herein, we report the discovery of an anomalous "strong metal-support bonding" between gold nanoparticles and "nano-engineered" Fe 3 O 4 substrates by in situ microscopy. During in situ vacuum annealing of Au-Fe 3 O 4 dumbbell-like nanoparticles, synthesized by the epitaxial growth of nano-Fe 3 O 4 on Au nanoparticles, the gold nanoparticles transform into the gold thin films and wet the surface of nano-Fe 3 O 4 , as the surface reduction of nano-Fe 3 O 4 proceeds. This phenomenon results from a unique coupling of the size-and shape-dependent high surface reducibility of nano-Fe 3 O 4 and the extremely strong adhesion between Au and the reduced Fe 3 O 4 . This strong metal-support bonding reveals the significance of controlling the metal oxide support size and morphology for optimizing metal-support bonding and ultimately for the development of improved catalysts and functional nanostructures.

  20. A Discovery of Strong Metal–Support Bonding in Nanoengineered Au–Fe 3 O 4 Dumbbell-like Nanoparticles by in Situ Transmission Electron Microscopy

    DOE PAGES

    Han, Chang Wan; Choksi, Tej; Milligan, Cory; ...

    2017-06-26

    The strength of metal-support bonding in heterogeneous catalysts determines their thermal stability, therefore, a tremendous amount of effort has been expended to understand metal-support interactions. Herein, we report the discovery of an anomalous “strong metal-support bonding” between gold nanoparticles and “nano-engineered” Fe 3O 4 substrates by in-situ microscopy. During in-situ vacuum annealing of Au-Fe 3O 4 dumbbell-like nanoparticles, synthesized by the epitaxial growth of nano-Fe 3O 4 on Au nanoparticles, the gold nanoparticles transform into the monolayered gold thinfilms and wet the surface of nano-Fe 3O 4, as the surface reduction of nano-Fe 3O 4 proceeds. This phenomenon results frommore » a unique coupling of the size-and shape-dependent high surface reducibility of nano-Fe 3O 4 and the extremely strong adhesion between Au and the reduced Fe 3O 4. This strong-metal support bonding reveals the significance of controlling the metal oxide support size and morphology for optimizing metal-support bonding and, ultimately, for the development of improved catalysts and functional nanostructures.« less

  1. Where the lake meets the sea: strong reproductive isolation is associated with adaptive divergence between lake resident and anadromous three-spined sticklebacks.

    PubMed

    Ravinet, Mark; Hynes, Rosaleen; Poole, Russell; Cross, Tom F; McGinnity, Phil; Harrod, Chris; Prodöhl, Paulo A

    2015-01-01

    Contact zones between divergent forms of the same species are often characterised by high levels of phenotypic diversity over small geographic distances. What processes are involved in generating such high phenotypic diversity? One possibility is that introgression and recombination between divergent forms in contact zones results in greater phenotypic and genetic polymorphism. Alternatively, strong reproductive isolation between forms may maintain distinct phenotypes, preventing homogenisation by gene flow. Contact zones between divergent freshwater-resident and anadromous stickleback (Gasterosteus aculeatus L.) forms are numerous and common throughout the species distribution, offering an opportunity to examine these contrasting hypotheses in greater detail. This study reports on an interesting new contact zone located in a tidally influenced lake catchment in western Ireland, characterised by high polymorphism for lateral plate phenotypes. Using neutral and QTL-linked microsatellite markers, we tested whether the high diversity observed in this contact zone arose as a result of introgression or reproductive isolation between divergent forms: we found strong support for the latter hypothesis. Three phenotypic and genetic clusters were identified, consistent with two divergent resident forms and a distinct anadromous completely plated population that migrates in and out of the system. Given the strong neutral differentiation detected between all three morphotypes (mean FST = 0.12), we hypothesised that divergent selection between forms maintains reproductive isolation. We found a correlation between neutral genetic and adaptive genetic differentiation that support this. While strong associations between QTL linked markers and phenotypes were also observed in this wild population, our results support the suggestion that such associations may be more complex in some Atlantic populations compared to those in the Pacific. These findings provide an important foundation for future work investigating the dynamics of gene flow and adaptive divergence in this newly discovered stickleback contact zone.

  2. Where the Lake Meets the Sea: Strong Reproductive Isolation Is Associated with Adaptive Divergence between Lake Resident and Anadromous Three-Spined Sticklebacks

    PubMed Central

    Ravinet, Mark; Hynes, Rosaleen; Poole, Russell; Cross, Tom F.; McGinnity, Phil; Harrod, Chris; Prodöhl, Paulo A.

    2015-01-01

    Contact zones between divergent forms of the same species are often characterised by high levels of phenotypic diversity over small geographic distances. What processes are involved in generating such high phenotypic diversity? One possibility is that introgression and recombination between divergent forms in contact zones results in greater phenotypic and genetic polymorphism. Alternatively, strong reproductive isolation between forms may maintain distinct phenotypes, preventing homogenisation by gene flow. Contact zones between divergent freshwater-resident and anadromous stickleback (Gasterosteus aculeatus L.) forms are numerous and common throughout the species distribution, offering an opportunity to examine these contrasting hypotheses in greater detail. This study reports on an interesting new contact zone located in a tidally influenced lake catchment in western Ireland, characterised by high polymorphism for lateral plate phenotypes. Using neutral and QTL-linked microsatellite markers, we tested whether the high diversity observed in this contact zone arose as a result of introgression or reproductive isolation between divergent forms: we found strong support for the latter hypothesis. Three phenotypic and genetic clusters were identified, consistent with two divergent resident forms and a distinct anadromous completely plated population that migrates in and out of the system. Given the strong neutral differentiation detected between all three morphotypes (mean FST = 0.12), we hypothesised that divergent selection between forms maintains reproductive isolation. We found a correlation between neutral genetic and adaptive genetic differentiation that support this. While strong associations between QTL linked markers and phenotypes were also observed in this wild population, our results support the suggestion that such associations may be more complex in some Atlantic populations compared to those in the Pacific. These findings provide an important foundation for future work investigating the dynamics of gene flow and adaptive divergence in this newly discovered stickleback contact zone. PMID:25874617

  3. Extravehicular Activity Systems Education and Public Outreach in Support of NASA's STEM Initiatives in Fiscal Year 2011

    NASA Technical Reports Server (NTRS)

    Paul, Heather; Jennings, Mallory A.; Lamberth, Erika Guillory

    2012-01-01

    NASA's goals to send humans beyond low Earth orbit will involve the need for a strong engineering workforce. Research indicates that student interest in science, technology, engineering, and math (STEM) areas is on the decline. According to the Department of Education, the United States President has mandated that 100,000 educators be trained in STEM over the next decade to reduce this trend. NASA has aligned its Education and Public Outreach (EPO) initiatives to include emphasis in promoting STEM. The Extravehicular Activity (EVA) Systems Project Office at the NASA Johnson Space Center actively supports this NASA initiative by providing subject matter experts and hands-on, interactive presentations to educate students, educators, and the general public about the design challenges encountered as NASA develops EVA hardware for exploration missions. This paper summarizes the EVA Systems EPO efforts and metrics from fiscal year 2011.

  4. Public health and national security: the critical role of increased federal support.

    PubMed

    Frist, Bill

    2002-01-01

    Protecting the public's health historically has been a state and local responsibility. However, the growing threat of bioterrorism has highlighted the importance of a strong public health infrastructure to the nation's homeland security and has focused increased attention on the preparedness of the public health system. As a result, federal public health funding has increased exponentially since the anthrax attacks of late 2001, and Congress has passed sweeping new federal legislation intended to strengthen the nation's public health system. This heightened level of federal interest and support should yield important public health benefits. Most recognize that after years of neglect the public health infrastructure cannot be rebuilt overnight. As we implement a comprehensive strategy to increase the capabilities and capacity of our nation's public health system, it is essential to address a series of important policy questions, including the appropriate level of ongoing public health investments from local, state, and federal sources.

  5. Efficient and resilient governance of social-ecological systems.

    PubMed

    Erickson, Adam

    2015-09-01

    New institutions are critically needed to improve the resilience of social-ecological systems globally. Watershed management offers an important model due to its ability to govern mixed-ownership landscapes through common property regimes, translating national goals into local action. Here, I assess the efficacy of state watershed management institutions in the Pacific Northwest, based on their ability to support local watershed groups. I use document analysis to describe and compare state institutions in Washington, Oregon, Idaho, and California. Results indicate that state institutional efficiency and resilience are the key factors determining watershed group activity and stability. The primary drivers of institutional efficiency and resilience were institutional unification, robust funding portfolios, low agency conflict, and strong support for economic multiplier effects, creative partnerships, and scholarly research. My findings elucidate the critical role of institutional efficiency and resilience in governing dynamic and complex social-ecological systems, enabling the flexibility to address emergent transformations.

  6. Extravehicular Activity Systems Education and Public Outreach in Support of NASA's STEM Initiatives in Fiscal Year 2011

    NASA Technical Reports Server (NTRS)

    Paul, Heather L.; Jennings, Mallory A.; Lamberth, Erika Guillory

    2011-01-01

    NASA's goals to send humans beyond low Earth orbit will involve the need for a strong engineering workforce. Research indicates that student interest in science, technology, engineering, and math (STEM) areas is on the decline. According to the Department of Education, the United States President has mandated that 100,000 educators be trained in STEM over the next decade to reduce this trend. NASA has aligned its Education and Public Outreach (EPO) initiatives to include emphasis in promoting STEM. The Extravehicular Activity (EVA) Systems Project Office at the NASA Johnson Space Center actively supports this NASA initiative by providing subject matter experts and hands-on, interactive presentations to educate students, educators, and the general public about the design challenges encountered as NASA develops EVA hardware for exploration missions. This paper summarizes the EVA Systems EPO efforts and metrics from fiscal year 2011.

  7. Canada's public health system: is the pace of progress sufficient?

    PubMed

    Lozon, Jeffrey C; Alikhan, L Miin

    2007-01-01

    Tilson and Berkowitz review the Institute of Medicine reports that catalyzed the serious re-examination of the United States public health enterprise. For Canada, a similar catalyst stemmed from the lessons learned during the 2003 severe acute respiratory syndrome outbreak. While strong policy statements of commitment to strengthen the public health system are a necessary first step to stewarding change, they are insufficient without defined accountabilities, operationalized relationships and supporting legislation. Investments in critical enablers of sustainable reform, such as inter-sectoral partnerships, human capacity building and an electronic backbone, are also required. To support the value added by public health functions and services, both from a health benefit and economic perspective, a performance management system is necessary. While the 2004 establishment of the Public Health Agency of Canada was a progressive step, persistent political will and leadership are required to ensure this agency's effectiveness and preparedness before the next crisis hits.

  8. Managing animal disease risk in Australia: the impact of climate change.

    PubMed

    Black, P F; Murray, J G; Nunn, M J

    2008-08-01

    Climate change is one of a number of factors that are likely to affect the future of Australian agriculture, animal production and animal health, particularly when associated with other factors such as environmental degradation, intensive animal production, an increasing human population, and expanding urbanisation. Notwithstanding the harshness and variability of Australia's climate, significant livestock industries have been developed, with the majority of products from such industries exported throughout the world. A critical factor in achieving market access has been an enviable animal health status, which is underpinned by first class animal health services with a strong legislative basis, well-trained staff, engagement of industry, effective surveillance, good scientific and laboratory support, effective emergency management procedures, a sound quarantine system, and strong political support. However, enhancements still need to be made to Australia's animal health system, for example: re-defining the science-policy interface; refining foresight, risk analysis, surveillance, diagnostics, and emergency management; improving approaches to education, training, technology transfer, communications and awareness; and engaging more with the international community in areas such as capacity building, the development of veterinary services, and disease response systems. A 'one health' approach will be adopted to bring together skills in the fields of animal, public, wildlife and environmental health. These initiatives, if managed correctly, will minimise the risks resulting from global warming and other factors predisposing to disease.

  9. Exact Critical Exponents for the Antiferromagnetic Quantum Critical Metal in Two Dimensions

    NASA Astrophysics Data System (ADS)

    Schlief, Andres; Lunts, Peter; Lee, Sung-Sik

    2017-04-01

    Unconventional metallic states which do not support well-defined single-particle excitations can arise near quantum phase transitions as strong quantum fluctuations of incipient order parameters prevent electrons from forming coherent quasiparticles. Although antiferromagnetic phase transitions occur commonly in correlated metals, understanding the nature of the strange metal realized at the critical point in layered systems has been hampered by a lack of reliable theoretical methods that take into account strong quantum fluctuations. We present a nonperturbative solution to the low-energy theory for the antiferromagnetic quantum critical metal in two spatial dimensions. Being a strongly coupled theory, it can still be solved reliably in the low-energy limit as quantum fluctuations are organized by a new control parameter that emerges dynamically. We predict the exact critical exponents that govern the universal scaling of physical observables at low temperatures.

  10. Applying the ecosystem services framework to pasture-based livestock farming systems in Europe.

    PubMed

    Rodríguez-Ortega, T; Oteros-Rozas, E; Ripoll-Bosch, R; Tichit, M; Martín-López, B; Bernués, A

    2014-08-01

    The concept of 'Ecosystem Services' (ES) focuses on the linkages between ecosystems, including agroecosystems, and human well-being, referring to all the benefits, direct and indirect, that people obtain from ecosystems. In this paper, we review the application of the ES framework to pasture-based livestock farming systems, which allows (1) regulating, supporting and cultural ES to be integrated at the same level with provisioning ES, and (2) the multiple trade-offs and synergies that exist among ES to be considered. Research on livestock farming has focused mostly on provisioning ES (meat, milk and fibre production), despite the fact that provisioning ES strongly depends on regulating and supporting ES for their existence. We first present an inventory of the non-provisioning ES (regulating, supporting and cultural) provided by pasture-based livestock systems in Europe. Next, we review the trade-offs between provisioning and non-provisioning ES at multiple scales and present an overview of the methodologies for assessing biophysical trade-offs. Third, we present non-biophysical (economical and socio-cultural) methodologies and applications for ES valuation. We conclude with some recommendations for policy design.

  11. Provenance Representation in the Global Change Information System (GCIS)

    NASA Technical Reports Server (NTRS)

    Tilmes, Curt

    2012-01-01

    Global climate change is a topic that has become very controversial despite strong support within the scientific community. It is common for agencies releasing information about climate change to be served with Freedom of Information Act (FOIA) requests for everything that led to that conclusion. Capturing and presenting the provenance, linking to the research papers, data sets, models, analyses, observation instruments and satellites, etc. supporting key findings has the potential to mitigate skepticism in this domain. The U.S. Global Change Research Program (USGCRP) is now coordinating the production of a National Climate Assessment (NCA) that presents our best understanding of global change. We are now developing a Global Change Information System (GCIS) that will present the content of that report and its provenance, including the scientific support for the findings of the assessment. We are using an approach that will present this information both through a human accessible web site as well as a machine readable interface for automated mining of the provenance graph. We plan to use the developing W3C PROV Data Model and Ontology for this system.

  12. Channel coding in the space station data system network

    NASA Technical Reports Server (NTRS)

    Healy, T.

    1982-01-01

    A detailed discussion of the use of channel coding for error correction, privacy/secrecy, channel separation, and synchronization is presented. Channel coding, in one form or another, is an established and common element in data systems. No analysis and design of a major new system would fail to consider ways in which channel coding could make the system more effective. The presence of channel coding on TDRS, Shuttle, the Advanced Communication Technology Satellite Program system, the JSC-proposed Space Operations Center, and the proposed 30/20 GHz Satellite Communication System strongly support the requirement for the utilization of coding for the communications channel. The designers of the space station data system have to consider the use of channel coding.

  13. Stable and Inert Cobalt Catalysts for Highly Selective and Practical Hydrogenation of C≡N and C═O Bonds.

    PubMed

    Chen, Feng; Topf, Christoph; Radnik, Jörg; Kreyenschulte, Carsten; Lund, Henrik; Schneider, Matthias; Surkus, Annette-Enrica; He, Lin; Junge, Kathrin; Beller, Matthias

    2016-07-20

    Novel heterogeneous cobalt-based catalysts have been prepared by pyrolysis of cobalt complexes with nitrogen ligands on different inorganic supports. The activity and selectivity of the resulting materials in the hydrogenation of nitriles and carbonyl compounds is strongly influenced by the modification of the support and the nitrogen-containing ligand. The optimal catalyst system ([Co(OAc)2/Phen@α-Al2O3]-800 = Cat. E) allows for efficient reduction of both aromatic and aliphatic nitriles including industrially relevant dinitriles to primary amines under mild conditions. The generality and practicability of this system is further demonstrated in the hydrogenation of diverse aliphatic, aromatic, and heterocyclic ketones as well as aldehydes, which are readily reduced to the corresponding alcohols.

  14. Identity and the Transition from School to Work in Late Modern Japan: Strong Agency or Supportive Communality?

    ERIC Educational Resources Information Center

    Inui, Akio; Kojima, Yoshikazu

    2012-01-01

    This article examines the precarious transition from school to work, considers its relation to young people's identity formation in late modern Japan, and rethinks the theory of identity formation in late modernity. Although Japan's transition system had been efficient and stable over many years, since the late 1990s this has been replaced by an…

  15. Biologist postdoctoral fellow | Center for Cancer Research

    Cancer.gov

    A fully funded postdoctoral position is available at the National Cancer Institute on the NIH main campus in Bethesda, MD.  Specifically, this opening is for an ongoing project examining the role of tissue architecture and mechanotransduction in the establishment of metastatic lesions, using zebrafish as a model system.  The NIH will provide funding and benefits, though extramural fellowship applications will be strongly encouraged and supported.

  16. Strong Families, Tidy Houses, and Children's Values in Adult Life: Are "Chaotic", "Crowded" and "Unstable" Homes Really so Bad?

    ERIC Educational Resources Information Center

    Flouri, Eirini

    2009-01-01

    Chaotic home systems have been linked with children's adverse psychological and academic outcomes. But, as they represent a departure from the suburban ideal of space, order, and family cohesiveness and stability, they should also be linked with low support for survival values. Using longitudinal data from the 1970 British Cohort Study (BCS70)…

  17. Assembly dynamics and stability of the pneumococcal epsilon zeta antitoxin toxin (PezAT) system from Streptococcus pneumoniae.

    PubMed

    Mutschler, Hannes; Reinstein, Jochen; Meinhart, Anton

    2010-07-09

    The pneumococcal epsilon zeta antitoxin toxin (PezAT) system is a chromosomally encoded, class II toxin antitoxin system from the human pathogen Streptococcus pneumnoniae. Neutralization of the bacteriotoxic protein PezT is carried out by complex formation with its cognate antitoxin PezA. Here we study the stability of the inhibitory complex in vivo and in vitro. We found that toxin release is impeded in Escherichia coli and Bacillus subtilis due to the proteolytic resistance of PezA once bound to PezT. These findings are supported by in vitro experiments demonstrating a strong thermodynamic stabilization of both proteins upon binding. A detailed kinetic analysis of PezAT assembly revealed that these particular features of PezAT are based on a strong, electrostatically guided binding mechanism leading to a stable toxin antitoxin complex with femtomolar affinity. Our data show that PezAT complex formation is distinct to all other conventional toxin antitoxin modules and a controlled mode of toxin release is required for activation.

  18. Use of HPLC/UPLC-spectrophotometry for detection of formazan in in vitro Reconstructed human Tissue (RhT)-based test methods employing the MTT-reduction assay to expand their applicability to strongly coloured test chemicals.

    PubMed

    Alépée, N; Barroso, J; De Smedt, A; De Wever, B; Hibatallah, J; Klaric, M; Mewes, K R; Millet, M; Pfannenbecker, U; Tailhardat, M; Templier, M; McNamee, P

    2015-06-01

    A number of in vitro test methods using Reconstructed human Tissues (RhT) are regulatory accepted for evaluation of skin corrosion/irritation. In such methods, test chemical corrosion/irritation potential is determined by measuring tissue viability using the photometric MTT-reduction assay. A known limitation of this assay is possible interference of strongly coloured test chemicals with measurement of formazan by absorbance (OD). To address this, Cosmetics Europe evaluated use of HPLC/UPLC-spectrophotometry as an alternative formazan measurement system. Using the approach recommended by the FDA guidance for validation of bio-analytical methods, three independent laboratories established and qualified their HPLC/UPLC-spectrophotometry systems to reproducibly measure formazan from tissue extracts. Up to 26 chemicals were then tested in RhT test systems for eye/skin irritation and skin corrosion. Results support that: (1) HPLC/UPLC-spectrophotometry formazan measurement is highly reproducible; (2) formazan measurement by HPLC/UPLC-spectrophotometry and OD gave almost identical tissue viabilities for test chemicals not exhibiting colour interference nor direct MTT reduction; (3) independent of the test system used, HPLC/UPLC-spectrophotometry can measure formazan for strongly coloured test chemicals when this is not possible by absorbance only. It is therefore recommended that HPLC/UPLC-spectrophotometry to measure formazan be included in the procedures of in vitro RhT-based test methods, irrespective of the test system used and the toxicity endpoint evaluated to extend the applicability of these test methods to strongly coloured chemicals. Copyright © 2015 Elsevier Ltd. All rights reserved.

  19. PRISM, Processing and Review Interface for Strong Motion Data Software

    NASA Astrophysics Data System (ADS)

    Kalkan, E.; Jones, J. M.; Stephens, C. D.; Ng, P.

    2016-12-01

    A continually increasing number of high-quality digital strong-motion records from stations of the National Strong Motion Project (NSMP) of the U.S. Geological Survey (USGS), as well as data from regional seismic networks within the U.S., calls for automated processing of strong-motion records with human review limited to selected significant or flagged records. The NSMP has developed the Processing and Review Interface for Strong Motion data (PRISM) software to meet this need. PRISM automates the processing of strong-motion records by providing batch-processing capabilities. The PRISM software is platform-independent (coded in Java), open-source, and does not depend on any closed-source or proprietary software. The software consists of two major components: a record processing engine composed of modules for each processing step, and a graphical user interface (GUI) for manual review and processing. To facilitate the use by non-NSMP earthquake engineers and scientists, PRISM (both its processing engine and GUI components) is easy to install and run as a stand-alone system on common operating systems such as Linux, OS X and Windows. PRISM was designed to be flexible and extensible in order to accommodate implementation of new processing techniques. Input to PRISM currently is limited to data files in the Consortium of Organizations for Strong-Motion Observation Systems (COSMOS) V0 format, so that all retrieved acceleration time series need to be converted to this format. Output products include COSMOS V1, V2 and V3 files as: (i) raw acceleration time series in physical units with mean removed (V1), (ii) baseline-corrected and filtered acceleration, velocity, and displacement time series (V2), and (iii) response spectra, Fourier amplitude spectra and common earthquake-engineering intensity measures (V3). A thorough description of the record processing features supported by PRISM is presented with examples and validation results. All computing features have been thoroughly tested.

  20. An empirical evaluation of graphical interfaces to support flight planning

    NASA Technical Reports Server (NTRS)

    Smith, Philip J.; Mccoy, Elaine; Layton, Chuck; Bihari, Tom

    1995-01-01

    Whether optimization techniques or expert systems technologies are used, the underlying inference processes and the model or knowledge base for a computerized problem-solving system are likely to be incomplete for any given complex, real-world task. To deal with the resultant brittleness, it has been suggested that 'cooperative' rather than 'automated' problem-solving systems be designed. Such cooperative systems are proposed to explicitly enhance the collaboration of people and the computer system when working in partnership to solve problems. This study evaluates the impact of alternative design concepts on the performance of airline pilots interacting with such a cooperative system designed to support enroute flight planning. Thirty pilots were studied using three different versions of the system. The results clearly demonstrate that different system design concepts can strongly influence the cognitive processes of users. Indeed, one of the designs studied caused four times as many pilots to accept a poor flight amendment. Based on think-aloud protocols, cognitive models are proposed to account for how features of the computer system interacted with specific types of scenarios to influence exploration and decision-making by the pilots. The results are then used to develop recommendations for guiding the design of cooperative systems.

  1. Efficacy of oxygen-supplying capacity of Azolla in a controlled life support system

    NASA Astrophysics Data System (ADS)

    Chen, Min; Deng, Sufang; Yang, Youquan; Huang, Yibing; Liu, Chongchu

    2012-02-01

    Azolla shows high growth and propagation rates, strong photosynthetic O2-releasing ability and high nutritional value. It is suitable as a salad vegetable and can be cultured on a multi-layered wet bed. Hence, it possesses potential as a fresh vegetable, and to release O2 and absorb CO2 in a Controlled Ecological Life Support System in space. In this study, we investigated the O2-providing characteristics of Azolla in a closed chamber under manned, controlled conditions to lay a foundation for use of Azolla as a biological component in ground simulation experiments for space applications. A closed test chamber, representing a Controlled Ecological Life Support System including an Azolla wet-culture device, was built to measure the changes in atmospheric O2 and CO2 concentrations inside the chamber in the presence of coexisting Azolla, fish and men. The amount of O2 consumed by fish was 0.0805-0.0831 L kg-1 h-1 and the level of CO2 emission was 0.0705-0.0736 L kg-1 h-1; O2 consumption by the two trial volunteers was 19.71 L h-1 and the volume of respiration-released CO2 was 18.90 L h-1. Under 7000-8000 Lx artificial light and Azolla wet-culture conditions, human and fish respiration and Azolla photosynthesis were complementary, thus the atmospheric O2 and CO2 concentrations inside chamber were maintained in equilibrium. The increase in atmospheric CO2 concentration in the closed chamber enhanced the net photosynthesis efficiency of the Azolla colony. This study showed that Azolla has strong photosynthetic O2-releasing ability, which equilibrates the O2 and CO2 concentrations inside the chamber in favor of human survival and verifies the potential of Azolla for space applications.

  2. Study on O2-supplying characteristics of Azolla in Controlled Ecological Life Support System

    NASA Astrophysics Data System (ADS)

    Chen, Min; Deng, Sufang; Yang, Youquang; Huang, Yibing; Liu, Zhongzhu

    Azolla has high growth and propagation rate, strong photosynthetic O2-releasing ability and rich nutrient value. It is able to be used as salad-type vegetable, and can also be cultured on wet bed in multi-layer condition. Hence, it possesses a potential functioning as providing O2, fresh vegetable and absorbing CO2 for Controlled Ecological Life Support System in space. In this study, we try to make clear the O2-providing characteristics of Azolla in controlled close chamber under manned condition in order to lay a foundation for Azolla as a biological component in the next ground simulated experiment and space application. A closed test cham-ber of Controlled Ecological Life Support System and Azolla wet-culturing devices were built to measure the changes of atmospheric O2-CO2 concentration inside chamber under "Azolla-fish -men" coexisting condition. The results showed that, the amount of O2 consumption is 80.49 83.07 ml/h per kilogram fish, the amount of CO2 emissions is 70.49 73.56 ml/(kg • h); O2 consumption of trial volunteers is 19.71 L/h, the volume of respiration release CO2 18.90 L/h .Artificial light intensity of Azolla wet culture under 70009000 Lx, people respiration and Azolla photosynthesis complemented each other, the atmospheric O2-CO2 concentration inside chamber maintained equilibration. Elevated atmospheric CO2 concentrations in close chamber have obvious effects on enhancing Azolla net photosynthesis efficiency. This shows that Azolla has strong photosynthetic O2-releasing ability, which equilibrates the O2-CO2 concentration inside chamber in favor of human survival, and then verifies the prospect of Azolla in space application.

  3. Fluid mixing and the deep biosphere of a fossil Lost City-type hydrothermal system at the Iberia Margin.

    PubMed

    Klein, Frieder; Humphris, Susan E; Guo, Weifu; Schubotz, Florence; Schwarzenbach, Esther M; Orsi, William D

    2015-09-29

    Subseafloor mixing of reduced hydrothermal fluids with seawater is believed to provide the energy and substrates needed to support deep chemolithoautotrophic life in the hydrated oceanic mantle (i.e., serpentinite). However, geosphere-biosphere interactions in serpentinite-hosted subseafloor mixing zones remain poorly constrained. Here we examine fossil microbial communities and fluid mixing processes in the subseafloor of a Cretaceous Lost City-type hydrothermal system at the magma-poor passive Iberia Margin (Ocean Drilling Program Leg 149, Hole 897D). Brucite-calcite mineral assemblages precipitated from mixed fluids ca. 65 m below the Cretaceous paleo-seafloor at temperatures of 31.7 ± 4.3 °C within steep chemical gradients between weathered, carbonate-rich serpentinite breccia and serpentinite. Mixing of oxidized seawater and strongly reducing hydrothermal fluid at moderate temperatures created conditions capable of supporting microbial activity. Dense microbial colonies are fossilized in brucite-calcite veins that are strongly enriched in organic carbon (up to 0.5 wt.% of the total carbon) but depleted in (13)C (δ(13)C(TOC) = -19.4‰). We detected a combination of bacterial diether lipid biomarkers, archaeol, and archaeal tetraethers analogous to those found in carbonate chimneys at the active Lost City hydrothermal field. The exposure of mantle rocks to seawater during the breakup of Pangaea fueled chemolithoautotrophic microbial communities at the Iberia Margin, possibly before the onset of seafloor spreading. Lost City-type serpentinization systems have been discovered at midocean ridges, in forearc settings of subduction zones, and at continental margins. It appears that, wherever they occur, they can support microbial life, even in deep subseafloor environments.

  4. Fluid mixing and the deep biosphere of a fossil Lost City-type hydrothermal system at the Iberia Margin

    PubMed Central

    Klein, Frieder; Humphris, Susan E.; Guo, Weifu; Schubotz, Florence; Schwarzenbach, Esther M.; Orsi, William D.

    2015-01-01

    Subseafloor mixing of reduced hydrothermal fluids with seawater is believed to provide the energy and substrates needed to support deep chemolithoautotrophic life in the hydrated oceanic mantle (i.e., serpentinite). However, geosphere-biosphere interactions in serpentinite-hosted subseafloor mixing zones remain poorly constrained. Here we examine fossil microbial communities and fluid mixing processes in the subseafloor of a Cretaceous Lost City-type hydrothermal system at the magma-poor passive Iberia Margin (Ocean Drilling Program Leg 149, Hole 897D). Brucite−calcite mineral assemblages precipitated from mixed fluids ca. 65 m below the Cretaceous paleo-seafloor at temperatures of 31.7 ± 4.3 °C within steep chemical gradients between weathered, carbonate-rich serpentinite breccia and serpentinite. Mixing of oxidized seawater and strongly reducing hydrothermal fluid at moderate temperatures created conditions capable of supporting microbial activity. Dense microbial colonies are fossilized in brucite−calcite veins that are strongly enriched in organic carbon (up to 0.5 wt.% of the total carbon) but depleted in 13C (δ13CTOC = −19.4‰). We detected a combination of bacterial diether lipid biomarkers, archaeol, and archaeal tetraethers analogous to those found in carbonate chimneys at the active Lost City hydrothermal field. The exposure of mantle rocks to seawater during the breakup of Pangaea fueled chemolithoautotrophic microbial communities at the Iberia Margin, possibly before the onset of seafloor spreading. Lost City-type serpentinization systems have been discovered at midocean ridges, in forearc settings of subduction zones, and at continental margins. It appears that, wherever they occur, they can support microbial life, even in deep subseafloor environments. PMID:26324888

  5. An integrated information system for the acquisition, management and sharing of environmental data aimed to decision making

    NASA Astrophysics Data System (ADS)

    La Loggia, Goffredo; Arnone, Elisa; Ciraolo, Giuseppe; Maltese, Antonino; Noto, Leonardo; Pernice, Umberto

    2012-09-01

    This paper reports the first results of the Project SESAMO - SistEma informativo integrato per l'acquisizione, geStione e condivisione di dati AMbientali per il supportO alle decisioni (Integrated Information System for the acquisition, management and sharing of environmental data aimed to decision making). The main aim of the project is to design and develop an integrated environmental information platform able to provide monitoring services for decision support, integrating data from different environmental monitoring systems (including WSN). This ICT platform, based on a service-oriented architecture (SOA), will be developed to coordinate a wide variety of data acquisition systems, based on heterogeneous technologies and communication protocols, providing different sort of environmental monitoring services. The implementation and validation of the SESAMO platform and its services will involve three specific environmental domains: 1) Urban water losses; 2) Early warning system for rainfall-induced landslides; 3) Precision irrigation planning. Services in the first domain are enabled by a low cost sensors network collecting and transmitting data, in order to allow the pipeline network managers to analyze pressure, velocity and discharge data for reducing water losses in an urban contest. This paper outlines the SESAMO functional and technological structure and then gives a concise description of the service design and development process for the second and third domain. Services in the second domain are enabled by a prototypal early warning system able to identify in near-real time high-risk zones of rainfall-induced landslides. Services in the third domain are aimed to optimize irrigation planning of vineyards depending on plant water stress.

  6. Assessing disease-modifying effects of norepinephrine in Down syndrome and Alzheimer's disease.

    PubMed

    Ponnusamy, Ravikumar; McNerney, M Windy; Moghadam, Shahrzad; Salehi, Ahmad

    2017-11-08

    Building upon the knowledge that a number of important brain circuits undergo significant degeneration in Alzheimer's disease, numerous recent studies suggest that the norepinephrine-ergic system in the brainstem undergoes significant alterations early in the course of both Alzheimer's disease and Down syndrome. Massive projections from locus coeruleus neurons to almost the entire brain, extensive innervation of brain capillaries, and widespread distribution of noradrenergic receptors enable the norepinephrine-ergic system to play a crucial role in neural processes, including cognitive function. These anatomical and functional characteristics support the role of the norepinephrine-ergic system as an important target for developing new therapies for cognitive dysfunction. Careful neuropathological examinations using postmortem samples from individuals with Alzheimer's disease have implicated the role of the norepinephrine-ergic system in the etiopathogenesis of Alzheimer's disease. Furthermore, numerous studies have supported the existence of a strong interaction between norepinephrine-ergic and neuroimmune systems. We explore the interaction between the two systems that could play a role in the disease-modifying effects of norepinephrine in Alzheimer's disease and Down syndrome. Copyright © 2017. Published by Elsevier B.V.

  7. Motorcycles, Cell Phones, and Electricity Can Dramatically Change the Epidemiology of Infectious Disease in Africa.

    PubMed

    Lagier, Jean-Christophe; Sokhna, Cheikh; Raoult, Didier

    2017-05-01

    AbstractSome observations and recent publications demonstrated, particularly in Africa, the potential influence that low-cost motorcycles, cell phones, and even widespread electrification could have on the evolution of infectious diseases, particularly zoonoses. Our reflections support the conclusion that we should focus on the real-time surveillance systems including alerting systems leading to a rapid and flexible response rather than the strongly limited modeling of infectious diseases because of the continuous evolution of microorganisms, as well as changes in the environment and human habits that are unpredictable.

  8. Evaluation of hot corrosion behavior of thermal barrier coatings

    NASA Technical Reports Server (NTRS)

    Hodge, P. E.; Miller, R. A.; Gedwill, M. A.

    1980-01-01

    Calcium silicate and yttria stabilized zirconia/MCrAlY thermal barrier coating systems on air-cooled specimens were exposed to sodium plus vanadium doped Mach 0.3 combustion gases. Thermal barrier coating endurance was determined to be a strong inverse function of ceramic coating thickness. Coating system durability was increased through the use of higher Cr + Al NiCrAl and CoCrAlY bond coatings. Chemical and electron microprobe analyses supported the predictions of condensate compositions and the determination of their roles in causing spalling of the ceramic coatings.

  9. Epsilon-near-zero modes for tailored light-matter interaction

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Campione, Salvatore; Liu, Sheng; Benz, Alexander

    Epsilon-near-zero (ENZ) modes arising from condensed-matter excitations such as phonons and plasmons are a new path for tailoring light-matter interactions at the nanoscale. Complex spectral shaping can be achieved by creating such modes in nanoscale semiconductor layers and controlling their interaction with multiple, distinct, dipole resonant systems. Examples of this behavior are presented at midinfrared frequencies for ENZ modes that are strongly coupled to metamaterial resonators and simultaneously strongly coupled to semiconductor phonons or quantum-well intersubband transitions (ISTs), resulting in double- and triple-polariton branches in transmission spectra. For the double-polariton branch case, we find that the best strategy to maximizemore » the Rabi splitting is to use a combination of a doped layer supporting an ENZ feature and a layer supporting ISTs, with overlapping ENZ and IST frequencies. As a result, this design flexibility renders this platform attractive for low-voltage tunable filters, light-emitting diodes, and efficient nonlinear composite materials.« less

  10. Epsilon-near-zero modes for tailored light-matter interaction

    DOE PAGES

    Campione, Salvatore; Liu, Sheng; Benz, Alexander; ...

    2015-10-20

    Epsilon-near-zero (ENZ) modes arising from condensed-matter excitations such as phonons and plasmons are a new path for tailoring light-matter interactions at the nanoscale. Complex spectral shaping can be achieved by creating such modes in nanoscale semiconductor layers and controlling their interaction with multiple, distinct, dipole resonant systems. Examples of this behavior are presented at midinfrared frequencies for ENZ modes that are strongly coupled to metamaterial resonators and simultaneously strongly coupled to semiconductor phonons or quantum-well intersubband transitions (ISTs), resulting in double- and triple-polariton branches in transmission spectra. For the double-polariton branch case, we find that the best strategy to maximizemore » the Rabi splitting is to use a combination of a doped layer supporting an ENZ feature and a layer supporting ISTs, with overlapping ENZ and IST frequencies. As a result, this design flexibility renders this platform attractive for low-voltage tunable filters, light-emitting diodes, and efficient nonlinear composite materials.« less

  11. Magnetic anisotropies and magnetic switching in Co films

    NASA Astrophysics Data System (ADS)

    Bland, J. A. C.; Baird, M. J.; Leung, H. T.; Ives, A. J. R.; Mackay, K. D.; Hughes, H. P.

    1992-07-01

    We have used the magneto-optical Kerr effect to investigate the role of the substrate and growth conditions in determining the magnetic switching behaviour of Co films in the thickness range 100-200 Å supported by GaAs(001) and Si(111) substrates. We discuss the anisotropic magnetic hysteresis behaviour observed for Co/GaAs and Co/Si films in terms of coherent rotation of the magnetisation vector during magnetic switching. Equivalent films supported by glass substrates are found to be almost isotropic in-plane. The in-plane coercive and saturation fields are observed to lie in the range 20-80 Oe but perpendicular saturation fields of 25 and 19 kOe are found for the Co/Si and Co/GaAs systems respectively which substantially exceed the demagnetising field in each case. The measured perpendicular anisotropy fields differ strongly from the values for hcp and bcc Co and are attributed to the details of the interface and film structure. We also report strongly frequency dependent magnetic switching behaviour in these Co films.

  12. Integrating molecular markers into the World Health Organization classification of CNS tumors: a survey of the neuro-oncology community.

    PubMed

    Aldape, Kenneth; Nejad, Romina; Louis, David N; Zadeh, Gelareh

    2017-03-01

    Molecular markers provide important biological and clinical information related to the classification of brain tumors, and the integration of relevant molecular parameters into brain tumor classification systems has been a widely discussed topic in neuro-oncology over the past decade. With recent advances in the development of clinically relevant molecular signatures and the 2016 World Health Organization (WHO) update, the views of the neuro-oncology community on such changes would be informative for implementing this process. A survey with 8 questions regarding molecular markers in tumor classification was sent to an email list of Society for Neuro-Oncology members and attendees of prior meetings (n=5065). There were 403 respondents. Analysis was performed using whole group response, based on self-reported subspecialty. The survey results show overall strong support for incorporating molecular knowledge into the classification and clinical management of brain tumors. Across all 7 subspecialty groups, ≥70% of respondents agreed to this integration. Interestingly, some variability is seen among subspecialties, notably with lowest support from neuropathologists, which may reflect their roles in implementing such diagnostic technologies. Based on a survey provided to the neuro-oncology community, we report strong support for the integration of molecular markers into the WHO classification of brain tumors, as well as for using an integrated "layered" diagnostic format. While membership from each specialty showed support, there was variation by specialty in enthusiasm regarding proposed changes. The initial results of this survey influenced the deliberations underlying the 2016 WHO classification of tumors of the central nervous system. © The Author(s) 2017. Published by Oxford University Press on behalf of the Society for Neuro-Oncology.

  13. A systematic review of patient tracking systems for use in the pediatric emergency department.

    PubMed

    Dobson, Ian; Doan, Quynh; Hung, Geoffrey

    2013-01-01

    Patient safety is of great importance in the pediatric emergency department (PED). The combination of acutely and critically ill patients and high patient volumes creates a need for systems to support physicians in making accurate and timely diagnoses. Electronic patient tracking systems can potentially improve PED safety by reducing overcrowding and enhancing security. To enhance our understanding of current electronic tracking technologies, how they are implemented in a clinical setting, and resulting effect on patient care outcomes including patient safety. Nine databases were searched. Two independent reviewers identified articles that contained reference to patient tracking technologies in pediatrics or emergency medicine. Quantitative studies were assessed independently for methodological strength by two reviewers using an external assessment tool. Of 2292 initial articles, 22 were deemed relevant. Seventeen were qualitative, and the remaining five quantitative articles were assessed as being methodologically weak. Existing patient tracking systems in the ED included: infant monitoring/abduction prevention; barcode identification; radiofrequency identification (RFID)- or infrared (IR)-based patient tracking. Twenty articles supported the use of tracking technology to enhance patient safety or improve efficiency. One article failed to support the use of IR patient sensors due to study design flaws. Support exists for the use of barcode-, IR-, and RFID-based patient tracking systems to improve ED patient safety and efficiency. A lack of methodologically strong studies indicates a need for further evidence-based support for the implementation of patient tracking technology in a clinical or research setting. Copyright © 2013 Elsevier Inc. All rights reserved.

  14. Canadian advanced life support capacities and future directions

    NASA Astrophysics Data System (ADS)

    Bamsey, M.; Graham, T.; Stasiak, M.; Berinstain, A.; Scott, A.; Vuk, T. Rondeau; Dixon, M.

    2009-07-01

    Canada began research on space-relevant biological life support systems in the early 1990s. Since that time Canadian capabilities have grown tremendously, placing Canada among the emerging leaders in biological life support systems. The rapid growth of Canadian expertise has been the result of several factors including a large and technically sophisticated greenhouse sector which successfully operates under challenging climatic conditions, well planned technology transfer strategies between the academic and industrial sectors, and a strong emphasis on international research collaborations. Recent activities such as Canada's contribution of the Higher Plant Compartment of the European Space Agency's MELiSSA Pilot Plant and the remote operation of the Arthur Clarke Mars Greenhouse in the Canadian High Arctic continue to demonstrate Canadian capabilities with direct applicability to advanced life support systems. There is also a significant latent potential within Canadian institutions and organizations with respect to directly applicable advanced life support technologies. These directly applicable research interests include such areas as horticultural management strategies (for candidate crops), growth media, food processing, water management, atmosphere management, energy management, waste management, imaging, environment sensors, thermal control, lighting systems, robotics, command and data handling, communications systems, structures, in-situ resource utilization, space analogues and mission operations. With this background and in collaboration with the Canadian aerospace industry sector, a roadmap for future life support contributions is presented here. This roadmap targets an objective of at least 50% food closure by 2050 (providing greater closure in oxygen, water recycling and carbon dioxide uptake). The Canadian advanced life support community has chosen to focus on lunar surface infrastructure and not low Earth orbit or transit systems (i.e. microgravity applications). To advance the technical readiness for the proposed lunar missions, including a lunar plant growth lander, lunar "salad machine" (i.e. small scale plant production unit) and a full scale lunar plant production system, a suite of terrestrial developments and analogue systems are proposed. As has been successfully demonstrated by past Canadian advanced life support activities, terrestrial technology transfer and the development of highly qualified personnel will serve as key outputs for Canadian advanced life support system research programs. This approach is designed to serve the Canadian greenhouse industry by developing compliance measures for mitigating environmental impact, reducing labour and energy costs as well as improving Canadian food security, safety and benefit northern/remote communities.

  15. Palladium Nanoparticle-Loaded Cellulose Paper: A Highly Efficient, Robust, and Recyclable Self-Assembled Composite Catalytic System.

    PubMed

    Zheng, Guangchao; Kaefer, Katharina; Mourdikoudis, Stefanos; Polavarapu, Lakshminarayana; Vaz, Belén; Cartmell, Samantha E; Bouleghlimat, Azzedine; Buurma, Niklaas J; Yate, Luis; de Lera, Ángel R; Liz-Marzán, Luis M; Pastoriza-Santos, Isabel; Pérez-Juste, Jorge

    2015-01-15

    We present a novel strategy based on the immobilization of palladium nanoparticles (Pd NPs) on filter paper for development of a catalytic system with high efficiency and recyclability. Oleylamine-capped Pd nanoparticles, dispersed in an organic solvent, strongly adsorb on cellulose filter paper, which shows a great ability to wick fluids due to its microfiber structure. Strong van der Waals forces and hydrophobic interactions between the particles and the substrate lead to nanoparticle immobilization, with no desorption upon further immersion in any solvent. The prepared Pd NP-loaded paper substrates were tested for several model reactions such as the oxidative homocoupling of arylboronic acids, the Suzuki cross-coupling reaction, and nitro-to-amine reduction, and they display efficient catalytic activity and excellent recyclability and reusability. This approach of using NP-loaded paper substrates as reusable catalysts is expected to open doors for new types of catalytic support for practical applications.

  16. Evidence from intrinsic activity that asymmetry of the human brain is controlled by multiple factors.

    PubMed

    Liu, Hesheng; Stufflebeam, Steven M; Sepulcre, Jorge; Hedden, Trey; Buckner, Randy L

    2009-12-01

    Cerebral lateralization is a fundamental property of the human brain and a marker of successful development. Here we provide evidence that multiple mechanisms control asymmetry for distinct brain systems. Using intrinsic activity to measure asymmetry in 300 adults, we mapped the most strongly lateralized brain regions. Both men and women showed strong asymmetries with a significant, but small, group difference. Factor analysis on the asymmetric regions revealed 4 separate factors that each accounted for significant variation across subjects. The factors were associated with brain systems involved in vision, internal thought (the default network), attention, and language. An independent sample of right- and left-handed individuals showed that hand dominance affects brain asymmetry but differentially across the 4 factors supporting their independence. These findings show the feasibility of measuring brain asymmetry using intrinsic activity fluctuations and suggest that multiple genetic or environmental mechanisms control cerebral lateralization.

  17. Influence of a breakwater on nearby rocky intertidal community structure.

    PubMed

    Martins, Gustavo M; Amaral, André F; Wallenstein, Francisco M; Neto, Ana I

    2009-01-01

    It is widely recognised that coastal-defence structures generally affect the structure of the assemblages they support, yet their impact on adjacent systems has been largely ignored. Breakwaters modify the nearby physical environment (e.g. wave action) suggesting a local impact on biological parameters. In the present study, an ACI (After-Control-Impact) design was used to test the general hypothesis that the artificial sheltering of an exposed coast has a strong effect on the structure and functioning of adjacent systems. The effects of a reduction in hydrodynamics were clear for a number of taxa and included the replacement of barnacles, limpets and frondose algae by an increasing cover of ephemeral algae. These effects were evident both at early and late successional stages. Results suggest that the artificial sheltering of naturally exposed coasts can have a strong impact promoting a shift from consumer- to producer-dominated communities, which has important ecological and energetic consequences for the ecosystem.

  18. Work stress and depression among direct support professionals: the role of work support and locus of control.

    PubMed

    Gray-Stanley, J A; Muramatsu, N; Heller, T; Hughes, S; Johnson, T P; Ramirez-Valles, J

    2010-08-01

    Although work stress can impede the capacity of direct support professionals and contribute to mental health challenges, external (i.e. work social support) and internal resources (i.e. an internal locus of control) have been shown to help DSPs cope more actively. We examined how work stress was associated with depression, with a particular focus on the role of resources. Direct support professionals (n = 323) who serve adults with intellectual and developmental disabilities from five community-based organisations completed a cross-sectional, self-administered survey which measured work stress, work support, locus of control, and depression. Multiple regression analyses demonstrated that work stress was positively associated with depression, while resources were negatively associated with depression. In particular, work support moderated the effects of client disability stress, supervisory support lessened the effects of role conflict, and locus of control moderated the effects of workload. Such findings suggest the importance of external and internal resources for staff mental health. This research underscores the need for strong work social support systems and interventions to help staff manage work stressors.

  19. Work stress and depression among direct support professionals: the role of work support and locus of control

    PubMed Central

    Gray-Stanley, J. A.; Muramatsu, N.; Heller, T.; Hughes, S.; Johnson, T. P.; Ramirez-Valles, J.

    2013-01-01

    Background Although work stress can impede the capacity of direct support professionals and contribute to mental health challenges, external (i.e. work social support) and internal resources (i.e. an internal locus of control) have been shown to help DSPs cope more actively. We examined how work stress was associated with depression, with a particular focus on the role of resources. Method Direct support professionals (n = 323) who serve adults with intellectual and developmental disabilities from five community-based organisations completed a cross-sectional, self-administered survey which measured work stress, work support, locus of control, and depression. Results Multiple regression analyses demonstrated that work stress was positively associated with depression, while resources were negatively associated with depression. In particular, work support moderated the effects of client disability stress, supervisory support lessened the effects of role conflict, and locus of control moderated the effects of workload. Conclusions Such findings suggest the importance of external and internal resources for staff mental health. This research underscores the need for strong work social support systems and interventions to help staff manage work stressors. PMID:20633203

  20. Can the exciton--polariton be defined by its quantum properties?

    NASA Astrophysics Data System (ADS)

    Fonseca-Romero, Karen; Cipagauta, Gustavo; Suárez-Forero, Daniel; Vinck-Posada, Herbert; Rey-González, Rafael; Herrera, William; Rodriguez, Boris

    2013-03-01

    We discuss the defining properties of a polariton in the framework of a microcavity-quantum dot system, described by a simple fully quantum model which takes into account loses and pumping. We show that even in the strong coupling regime, and provided that the emitted light exhibit subpoissonian statistics, the density operator of the system can be so mixed that quantum matter-radiation correlations are absent. We suggest the inclusion of matter-radiation entanglement as a defining property of the polariton. The weak-coupling, strong-coupling and lasing regimes, usually identified through the photoluminescence of the emitted light, can be understood in terms of quantum properties of the system state (entanglement, mixedness and light correlation functions). Our numerical anaylisis reveals the fundamental role of detuning on the coherence properties of the emitted light and on entanglement. In this sense, there is no polariton near resonance, even in the strong coupling regime. We show that the ``best'' polariton (maximally entangled matter-light state) is found when the exciton pumping rate is equal to the photon decay rate, and the detuning is of the order of three times the value of the coupling constant. The authors acknowledge partial financial support from Dirección de Investigación - Sede Bogotá, Universidad Nacional de Colombia (DIB-UNAL) under project 12584.

  1. Screening and transport in 2D semiconductor systems at low temperatures

    PubMed Central

    Das Sarma, S.; Hwang, E. H.

    2015-01-01

    Low temperature carrier transport properties in 2D semiconductor systems can be theoretically well-understood within RPA-Boltzmann theory as being limited by scattering from screened Coulomb disorder arising from random quenched charged impurities in the environment. In this work, we derive a number of analytical formula, supported by realistic numerical calculations, for the relevant density, mobility, and temperature range where 2D transport should manifest strong intrinsic (i.e., arising purely from electronic effects) metallic temperature dependence in different semiconductor materials arising entirely from the 2D screening properties, thus providing an explanation for why the strong temperature dependence of the 2D resistivity can only be observed in high-quality and low-disorder 2D samples and also why some high-quality 2D materials manifest much weaker metallicity than other materials. We also discuss effects of interaction and disorder on the 2D screening properties in this context as well as compare 2D and 3D screening functions to comment why such a strong intrinsic temperature dependence arising from screening cannot occur in 3D metallic carrier transport. Experimentally verifiable predictions are made about the quantitative magnitude of the maximum possible low-temperature metallicity in 2D systems and the scaling behavior of the temperature scale controlling the quantum to classical crossover. PMID:26572738

  2. Cultural Differences in Support Provision: The Importance of Relationship Quality.

    PubMed

    Chen, Jacqueline M; Kim, Heejung S; Sherman, David K; Hashimoto, Takeshi

    2015-11-01

    Emotional expression is highly valued in individualistic cultures, whereas emotional restraint is prioritized in collectivistic cultures. We hypothesized that high-quality relationships in these cultures would exhibit the forms of support provision congruent with their respective expectations. Study 1 examined support transactions among friends in response to a laboratory stressor and found that objectively judged relationship quality (RQ) more strongly positively predicted emotion-focused support provision behaviors by European Americans than by Asian Americans. Study 2, a questionnaire study, found that self-reported RQ predicted emotion-focused support provision more strongly among European Americans than among Japanese. Study 3 investigated more indirect forms of support and found that RQ more strongly predicted worrying about and monitoring close others enduring stressors and spending time with them without talking about the stressor among Asian Americans compared with European Americans. These findings suggest that RQ is expressed in terms of support provision in culturally normative ways. © 2015 by the Society for Personality and Social Psychology, Inc.

  3. A smartphone-enabled communication system to improve hospital communication: usage and perceptions of medical trainees and nurses on general internal medicine wards.

    PubMed

    Wu, Robert; Lo, Vivian; Morra, Dante; Appel, Eva; Arany, Teri; Curiale, Beth; Ryan, Joanne; Quan, Sherman

    2015-02-01

    There is increasing interest in the use of information and communication technologies to improve how clinicians communicate in hospital settings. We implemented a communication system with support for physician handover and secure messaging on 2 general internal medicine wards. We measured usage and surveyed physicians and nurses on perceptions of the system's effects on communication. Between May 2011 and August 2012, a clinical teaching team received, on average, 14.8 messages per day through the system. Messages were typically sent as urgent (69.1%) and requested a text reply (76.5%). For messages requesting a text reply, 8.6% did not receive a reply. For those messages that did receive a reply, the median response time was 2.3 minutes, and 84.5% of messages received a reply within 15 minutes. Of those who completed the survey, 95.3% were medical residents (82 of 86) and 81.7% were nurses (83 of 116). Medical trainees (82.8%) and nursing staff (78.3%) agreed or strongly agreed that the system helped to speed up their daily work tasks. Overall, 67.1% of the trainees and 73.2% of nurses agreed or strongly agreed that the system made them more accountable in their clinical roles. Only 35.8% of physicians and 26.3% of nurses agreed or strongly agreed that the system was useful for communicating complex issues. In summary, with a system designed to improve communication, we found that there was high uptake and that users perceived that the system improved efficiency and accountability but was not appropriate for communicating complex issues. © 2014 Society of Hospital Medicine.

  4. NEUTRONIC REACTOR CORE

    DOEpatents

    Thomson, W.B.; Corbin, A. Jr.

    1961-07-18

    An improved core for a gas-cooled power reactor which admits gas coolant at high temperatures while affording strong integral supporting structure and efficient moderation of neutrons is described. The multiplicities of fuel elements constituting the critical amassment of fissionable material are supported and confined by a matrix of metallic structure which is interspersed therebetween. Thermal insulation is interposed between substantially all of the metallic matrix and the fuel elements; the insulation then defines the principal conduit system for conducting the coolant gas in heat-transfer relationship with the fuel elements. The metallic matrix itseif comprises a system of ducts through which an externally-cooled hydrogeneous liquid, such as water, is circulated to serve as the principal neutron moderant for the core and conjointly as the principal coolant for the insulated metallic structure. In this way, use of substantially neutron transparent metals, such as aluminum, becomes possible for the supporting structure, despite the high temperatures of the proximate gas. The Aircraft Nuclear Propulsion program's "R-1" reactor design is a preferred embodiment.

  5. Models for liquid-liquid partition in the system dimethyl sulfoxide-organic solvent and their use for estimating descriptors for organic compounds.

    PubMed

    Karunasekara, Thushara; Poole, Colin F

    2011-07-15

    Partition coefficients for varied compounds were determined for the organic solvent-dimethyl sulfoxide biphasic partition system where the organic solvent is n-heptane or isopentyl ether. These partition coefficient databases are analyzed using the solvation parameter model facilitating a quantitative comparison of the dimethyl sulfoxide-based partition systems with other totally organic partition systems. Dimethyl sulfoxide is a moderately cohesive solvent, reasonably dipolar/polarizable and strongly hydrogen-bond basic. Although generally considered to be non-hydrogen-bond acidic, analysis of the partition coefficient database strongly supports reclassification as a weak hydrogen-bond acid in agreement with recent literature. The system constants for the n-heptane-dimethyl sulfoxide biphasic system provide an explanation of the mechanism for the selective isolation of polycyclic aromatic compounds from mixtures containing low-polarity hydrocarbons based on the capability of the polar interactions (dipolarity/polarizability and hydrogen-bonding) to overcome the opposing cohesive forces in dimethyl sulfoxide that are absent for the interactions with hydrocarbons of low polarity. In addition, dimethyl sulfoxide-organic solvent systems afford a complementary approach to other totally organic biphasic partition systems for descriptor measurements of compounds virtually insoluble in water. Copyright © 2011 Elsevier B.V. All rights reserved.

  6. Lenstronomy: Multi-purpose gravitational lens modeling software package

    NASA Astrophysics Data System (ADS)

    Birrer, Simon; Amara, Adam

    2018-04-01

    Lenstronomy is a multi-purpose open-source gravitational lens modeling python package. Lenstronomy reconstructs the lens mass and surface brightness distributions of strong lensing systems using forward modelling and supports a wide range of analytic lens and light models in arbitrary combination. The software is also able to reconstruct complex extended sources as well as point sources. Lenstronomy is flexible and numerically accurate, with a clear user interface that could be deployed across different platforms. Lenstronomy has been used to derive constraints on dark matter properties in strong lenses, measure the expansion history of the universe with time-delay cosmography, measure cosmic shear with Einstein rings, and decompose quasar and host galaxy light.

  7. Triple Aim in Canada: developing capacity to lead to better health, care and cost

    PubMed Central

    Farmanova, Elina; Kirvan, Christine; Verma, Jennifer; Mukerji, Geetha; Akunov, Nurdin; Phillips, Kaye; Samis, Stephen

    2016-01-01

    Abstract Quality problem Many modern health systems strive for ‘Triple Aim’ (TA)—better health for populations, improved experience of care for patients and lower costs of the system, but note challenges in implementation. Outcomes of applying TA as a quality improvement framework (QI) have started to be realized with early lessons as to why some systems make progress while others do not. Initial assessment Limited evidence is available as to how organizations create the capacity and infrastructure required to design, implement, evaluate and sustain TA systems. Choice of solution To support embedding TA across Canada, the Canadian Foundation for Healthcare Improvement supported enrolment of nine Canadian teams to participate in the Institute for Healthcare Improvement's TA Improvement Community. Implementation Structured support for TA design, implementation, evaluation and sustainability was addressed in a collaborative programme of webinars and action periods. Teams were coached to undertake and test small-scale improvements before attempting to scale. Evaluation A summative evaluation of the Canadian cohort was undertaken to assess site progress in building TA infrastructure across various healthcare settings. The evaluation explored the process of change, experiences and challenges and strategies for continuous QI. Lessons learned Delivering TA requires a sustained and coordinated effort supported by strong leadership and governance, continuous QI, engaged interdisciplinary teams and partnering within and beyond the healthcare sector. PMID:28423164

  8. Participatory Research to Design a Novel Telehealth System to Support the Night-Time Needs of People with Dementia: NOCTURNAL

    PubMed Central

    Martin, Suzanne; Augusto, Juan Carlos; Mc Cullagh, Paul; Carswell, William; Zheng, Huiru; Wang, Haiying; Wallace, Jonathan; Mulvenna, Maurice

    2013-01-01

    Strategies to support people living with dementia are broad in scope, proposing both pharmacological and non-pharmacological interventions as part of the care pathway. Assistive technologies form part of this offering as both stand-alone devices to support particular tasks and the more complex offering of the “smart home” to underpin ambient assisted living. This paper presents a technology-based system, which expands on the smart home architecture, orientated to support people with daily living. The system, NOCTURNAL, was developed by working directly with people who had dementia, and their carers using qualitative research methods. The research focused primarily on the nighttime needs of people living with dementia in real home settings. Eight people with dementia had the final prototype system installed for a three month evaluation at home. Disturbed sleep patterns, night-time wandering were a focus of this research not only in terms of detection by commercially available technology but also exploring if automated music, light and visual personalized photographs would be soothing to participants during the hours of darkness. The NOCTURNAL platform and associated services was informed by strong user engagement of people with dementia and the service providers who care for them. NOCTURNAL emerged as a holistic service offering a personalised therapeutic aspect with interactive capabilities. PMID:24304507

  9. Triple Aim in Canada: developing capacity to lead to better health, care and cost.

    PubMed

    Farmanova, Elina; Kirvan, Christine; Verma, Jennifer; Mukerji, Geetha; Akunov, Nurdin; Phillips, Kaye; Samis, Stephen

    2016-12-01

    Many modern health systems strive for 'Triple Aim' (TA)-better health for populations, improved experience of care for patients and lower costs of the system, but note challenges in implementation. Outcomes of applying TA as a quality improvement framework (QI) have started to be realized with early lessons as to why some systems make progress while others do not. Limited evidence is available as to how organizations create the capacity and infrastructure required to design, implement, evaluate and sustain TA systems. To support embedding TA across Canada, the Canadian Foundation for Healthcare Improvement supported enrolment of nine Canadian teams to participate in the Institute for Healthcare Improvement's TA Improvement Community. Structured support for TA design, implementation, evaluation and sustainability was addressed in a collaborative programme of webinars and action periods. Teams were coached to undertake and test small-scale improvements before attempting to scale. A summative evaluation of the Canadian cohort was undertaken to assess site progress in building TA infrastructure across various healthcare settings. The evaluation explored the process of change, experiences and challenges and strategies for continuous QI. Delivering TA requires a sustained and coordinated effort supported by strong leadership and governance, continuous QI, engaged interdisciplinary teams and partnering within and beyond the healthcare sector. © The Author 2016. Published by Oxford University Press in association with the International Society for Quality in Health Care.

  10. Critical interactions between Global Fund-supported programmes and health systems: a case study in Lao People's Democratic Republic.

    PubMed

    Mounier-Jack, Sandra; Rudge, James W; Phetsouvanh, Rattanaxay; Chanthapadith, Chansouk; Coker, Richard

    2010-11-01

    In Lao PDR, investment by the Global Fund to Fight AIDS, Tuberculosis and Malaria has played an important role in scaling up the response to HIV and tuberculosis (TB). As part of a series of case studies on how Global Fund-supported programmes interact with national health systems, we assessed the nature and extent of integration of the Global Fund portfolios within the national HIV and TB programmes, the integration of the HIV and TB programmes within the general health system, and system-wide effects of Global Fund support in Lao PDR. The study relied on a literature review and 35 interviews with key stakeholders using the Systemic Rapid Assessment Toolkit and thematic analysis. In Lao PDR, the HIV and TB programmes remain vertical and mostly weakly integrated with the general health system. However, Global Fund investments have extended the network of facilities delivering care at local level, resulting in greater integration with primary care and improved access for patients, particularly for TB. For HIV, as the prevalence remains low, services primarily target high-risk groups in urban areas. Less integrated functions include procurement and drug supply, and monitoring and evaluation. HIV and TB programmes are only starting to coordinate with each other. Global Fund-supported activities are generally integrated within the national disease programmes, except for monitoring and evaluation. Synergies of Global Fund support with the health system include improved access to services, institutional strengthening and capacity building, improved family planning (with wider condom distribution through HIV/AIDS social marketing programmes), and the delivery of add-on interventions, such as vaccinations and health education, alongside Global Fund-supported interventions at community level. Unintended consequences concern the lack of alignment between national stated priorities (maternal and child health) and the strong focus of external partners, such as the Global Fund, on financing communicable disease programmes.

  11. Planetary explorer liquid propulsion study

    NASA Technical Reports Server (NTRS)

    Mckevitt, F. X.; Eggers, R. F.; Bolz, C. W.

    1971-01-01

    An analytical evaluation of several candidate monopropellant hydrazine propulsion system approaches is conducted in order to define the most suitable configuration for the combined velocity and attitude control system for the Planetary Explorer spacecraft. Both orbiter and probe-type missions to the planet Venus are considered. The spacecraft concept is that of a Delta launched spin-stabilized vehicle. Velocity control is obtained through preprogrammed pulse-mode firing of the thrusters in synchronism with the spacecraft spin rate. Configuration selection is found to be strongly influenced by the possible error torques induced by uncertainties in thruster operation and installation. The propulsion systems defined are based on maximum use of existing, qualified components. Ground support equipment requirements are defined and system development testing outlined.

  12. Architecting the Communication and Navigation Networks for NASA's Space Exploration Systems

    NASA Technical Reports Server (NTRS)

    Bhassin, Kul B.; Putt, Chuck; Hayden, Jeffrey; Tseng, Shirley; Biswas, Abi; Kennedy, Brian; Jennings, Esther H.; Miller, Ron A.; Hudiburg, John; Miller, Dave; hide

    2007-01-01

    NASA is planning a series of short and long duration human and robotic missions to explore the Moon and then Mars. A key objective of the missions is to grow, through a series of launches, a system of systems communication, navigation, and timing infrastructure at minimum cost while providing a network-centric infrastructure that maximizes the exploration capabilities and science return. There is a strong need to use architecting processes in the mission pre-formulation stage to describe the systems, interfaces, and interoperability needed to implement multiple space communication systems that are deployed over time, yet support interoperability with each deployment phase and with 20 years of legacy systems. In this paper we present a process for defining the architecture of the communications, navigation, and networks needed to support future space explorers with the best adaptable and evolable network-centric space exploration infrastructure. The process steps presented are: 1) Architecture decomposition, 2) Defining mission systems and their interfaces, 3) Developing the communication, navigation, networking architecture, and 4) Integrating systems, operational and technical views and viewpoints. We demonstrate the process through the architecture development of the communication network for upcoming NASA space exploration missions.

  13. [Physiotherapeutic care marketing research: current state-of-the art].

    PubMed

    Babaskin, D V

    2011-01-01

    Successful introduction of modern technologies into the national health care systems strongly depends on the current pharmaceutical market situation. The present article is focused on the peculiarities of marketing research with special reference to physiotherapeutic services and commodities. Analysis of the structure and sequence of marketing research processes is described along with the methods applied for the purpose including their support by the use of Internet resources and technologies.

  14. A Framework for Advancing Career and Technical Education: Recommendations for the Reauthorization of the Carl D. Perkins Act. Policy Brief

    ERIC Educational Resources Information Center

    Alliance for Excellent Education, 2012

    2012-01-01

    The nation's economy is only as strong as the educational foundation that supports it. Economic success in the twenty-first century requires a labor force capable of demonstrating an advanced level of both knowledge and skill. To be a true engine of growth, the nation's education system must be aligned with these demands. This is why the…

  15. Analysis of Instructional Support Elements for an Online, Educational Simulation on Active Listening for Women Graduate Students in Science and Engineering

    ERIC Educational Resources Information Center

    Bernstein, Bianca L.; Bekki, Jennifer M.; Wilkins, Kerrie G.; Harrison, Caroline J.

    2016-01-01

    Strong interpersonal communication skills (ICS) are critical for educational and career success, but effective and widely accessible training systems are not available. This paper describes a 2 × 2 × 2 experimental study of an online, educational simulation for practice with the ICS of active listening. The simulation was customized for women…

  16. The role of East Asian monsoon system in shaping population divergence and dynamics of a constructive desert shrub Reaumuria soongarica

    PubMed Central

    Yin, Hengxia; Yan, Xia; Shi, Yong; Qian, Chaoju; Li, Zhonghu; Zhang, Wen; Wang, Lirong; Li, Yi; Li, Xiaoze; Chen, Guoxiong; Li, Xinrong; Nevo, Eviatar; Ma, Xiao-Fei

    2015-01-01

    Both of the uplift of Qinghai-Tibet Plateau (QTP) and the development of East Asian monsoon system (EAMS) could have comprehensively impacted the formation and evolution of Arid Central Asia (ACA). To understand how desert plants endemic to ACA responded to these two factors, we profiled the historical population dynamics and distribution range shift of a constructive desert shrub Reaumuria soongarica (Tamaricaceae) based on species wide investigation of sequence variation of chloroplast DNA and nuclear ribosomal ITS. Phylogenetic analysis uncovered a deep divergence occurring at ca. 2.96 Mya between the western and eastern lineages of R. soongarica, and ecological niche modeling analysis strongly supported that the monsoonal climate could have fragmented its habitats in both glacial and interglacial periods and impelled its intraspecific divergence. Additionally, the population from the east monsoonal zone expanded rapidly, suggesting that the local monsoonal climate significantly impacted its population dynamics. The isolation by distance tests supported strong maternal gene flow along the direction of the East Asian winter monsoon, whose intensification induced the genetic admixture along the latitudinal populations of R. soongarica. Our results presented a new case that the development of EAMS had prominently impacted the intraspecific divergence and population dynamics of this desert plant. PMID:26510579

  17. Argo workstation: a key component of operational oceanography

    NASA Astrophysics Data System (ADS)

    Dong, Mingmei; Xu, Shanshan; Miao, Qingsheng; Yue, Xinyang; Lu, Jiawei; Yang, Yang

    2018-02-01

    Operational oceanography requires the quantity, quality, and availability of data set and the timeliness and effectiveness of data products. Without steady and strong operational system supporting, operational oceanography will never be proceeded far. In this paper we describe an integrated platform named Argo Workstation. It operates as a data processing and management system, capable of data collection, automatic data quality control, visualized data check, statistical data search and data service. After it is set up, Argo workstation provides global high quality Argo data to users every day timely and effectively. It has not only played a key role in operational oceanography but also set up an example for operational system.

  18. Bold Diagrammatic Monte Carlo for Fermionic and Fermionized Systems

    NASA Astrophysics Data System (ADS)

    Svistunov, Boris

    2013-03-01

    In three different fermionic cases--repulsive Hubbard model, resonant fermions, and fermionized spins-1/2 (on triangular lattice)--we observe the phenomenon of sign blessing: Feynman diagrammatic series features finite convergence radius despite factorial growth of the number of diagrams with diagram order. Bold diagrammatic Monte Carlo technique allows us to sample millions of skeleton Feynman diagrams. With the universal fermionization trick we can fermionize essentially any (bosonic, spin, mixed, etc.) lattice system. The combination of fermionization and Bold diagrammatic Monte Carlo yields a universal first-principle approach to strongly correlated lattice systems, provided the sign blessing is a generic fermionic phenomenon. Supported by NSF and DARPA

  19. A Survey on Wireless Body Area Networks for eHealthcare Systems in Residential Environments

    PubMed Central

    Ghamari, Mohammad; Janko, Balazs; Sherratt, R. Simon; Harwin, William; Piechockic, Robert; Soltanpur, Cinna

    2016-01-01

    Current progress in wearable and implanted health monitoring technologies has strong potential to alter the future of healthcare services by enabling ubiquitous monitoring of patients. A typical health monitoring system consists of a network of wearable or implanted sensors that constantly monitor physiological parameters. Collected data are relayed using existing wireless communication protocols to a base station for additional processing. This article provides researchers with information to compare the existing low-power communication technologies that can potentially support the rapid development and deployment of WBAN systems, and mainly focuses on remote monitoring of elderly or chronically ill patients in residential environments. PMID:27338377

  20. A Survey on Wireless Body Area Networks for eHealthcare Systems in Residential Environments.

    PubMed

    Ghamari, Mohammad; Janko, Balazs; Sherratt, R Simon; Harwin, William; Piechockic, Robert; Soltanpur, Cinna

    2016-06-07

    Current progress in wearable and implanted health monitoring technologies has strong potential to alter the future of healthcare services by enabling ubiquitous monitoring of patients. A typical health monitoring system consists of a network of wearable or implanted sensors that constantly monitor physiological parameters. Collected data are relayed using existing wireless communication protocols to a base station for additional processing. This article provides researchers with information to compare the existing low-power communication technologies that can potentially support the rapid development and deployment of WBAN systems, and mainly focuses on remote monitoring of elderly or chronically ill patients in residential environments.

  1. Recent Trends in Fusion Gyrotron Development at KIT

    NASA Astrophysics Data System (ADS)

    Gantenbein, G.; Avramidis, K.; Franck, J.; Illy, S.; Ioannidis, Z. C.; Jin, J.; Jelonnek, J.; Kalaria, P.; Pagonakis, I. Gr.; Ruess, S.; Rzesnicki, T.; Thumm, M.; Wu, C.

    2017-10-01

    ECRH&CD is one of the favorite heating system for magnetically confined nuclear fusion plasmas. KIT is strongly involved in the development of high power gyrotrons for use in ECRH systems for nuclear fusion. KIT is upgrading the sub-components of the existing 2 MW, 170 GHz coaxial-cavity short-pulse gyrotron to support long-pulse operation up to 1 s, all components will be equipped with a specific active cooling system. Two important developments for future high power, highly efficient gyrotrons will be discussed: design of gyrotrons with high operating frequency (˜ 240 GHz) and efficiency enhancement by using advanced collector designs with multi-staged voltage depression.

  2. Adaptation to sensory input tunes visual cortex to criticality

    NASA Astrophysics Data System (ADS)

    Shew, Woodrow L.; Clawson, Wesley P.; Pobst, Jeff; Karimipanah, Yahya; Wright, Nathaniel C.; Wessel, Ralf

    2015-08-01

    A long-standing hypothesis at the interface of physics and neuroscience is that neural networks self-organize to the critical point of a phase transition, thereby optimizing aspects of sensory information processing. This idea is partially supported by strong evidence for critical dynamics observed in the cerebral cortex, but the impact of sensory input on these dynamics is largely unknown. Thus, the foundations of this hypothesis--the self-organization process and how it manifests during strong sensory input--remain unstudied experimentally. Here we show in visual cortex and in a computational model that strong sensory input initially elicits cortical network dynamics that are not critical, but adaptive changes in the network rapidly tune the system to criticality. This conclusion is based on observations of multifaceted scaling laws predicted to occur at criticality. Our findings establish sensory adaptation as a self-organizing mechanism that maintains criticality in visual cortex during sensory information processing.

  3. Clinical decision support: effectiveness in improving quality processes and clinical outcomes and factors that may influence success.

    PubMed

    Murphy, Elizabeth V

    2014-06-01

    The use of electronic health records has skyrocketed following the 2009 HITECH Act, which provides financial incentives to health care providers for the "meaningful use" of electronic medical record systems. An important component of the "Meaningful Use" legislation is the integration of Clinical Decision Support Systems (CDSS) into the computerized record, providing up-to-date medical knowledge and evidence-based guidance to the physician at the point of care. As reimbursement is increasingly tied to process and clinical outcomes, CDSS will be integral to future medical practice. Studies of CDSS indicate improvement in preventive services, appropriate care, and clinical and cost outcomes with strong evidence for CDSS effectiveness in process measures. Increasing provider adherence to CDSS recommendations is essential in improving CDSS effectiveness, and factors that influence adherence are currently under study.

  4. Coupling of individual quantum emitters to channel plasmons.

    PubMed

    Bermúdez-Ureña, Esteban; Gonzalez-Ballestero, Carlos; Geiselmann, Michael; Marty, Renaud; Radko, Ilya P; Holmgaard, Tobias; Alaverdyan, Yury; Moreno, Esteban; García-Vidal, Francisco J; Bozhevolnyi, Sergey I; Quidant, Romain

    2015-08-07

    Efficient light-matter interaction lies at the heart of many emerging technologies that seek on-chip integration of solid-state photonic systems. Plasmonic waveguides, which guide the radiation in the form of strongly confined surface plasmon-polariton modes, represent a promising solution to manipulate single photons in coplanar architectures with unprecedented small footprints. Here we demonstrate coupling of the emission from a single quantum emitter to the channel plasmon polaritons supported by a V-groove plasmonic waveguide. Extensive theoretical simulations enable us to determine the position and orientation of the quantum emitter for optimum coupling. Concomitantly with these predictions, we demonstrate experimentally that 42% of a single nitrogen-vacancy centre emission efficiently couples into the supported modes of the V-groove. This work paves the way towards practical realization of efficient and long distance transfer of energy for integrated solid-state quantum systems.

  5. Nuclear Cryogenic Propulsion Stage Conceptual Design and Mission Analysis

    NASA Technical Reports Server (NTRS)

    Kos, Larry D.; Russell, Tiffany E.

    2014-01-01

    The Nuclear Cryogenic Propulsion Stage (NCPS) is an in-space transportation vehicle, comprised of three main elements, designed to support a long-stay human Mars mission architecture beginning in 2035. The stage conceptual design and the mission analysis discussed here support the current nuclear thermal propulsion going on within partnership activity of NASA and the Department of Energy (DOE). The transportation system consists of three elements: 1) the Core Stage, 2) the In-line Tank, and 3) the Drop Tank. The driving mission case is the piloted flight to Mars in 2037 and will be the main point design shown and discussed. The corresponding Space Launch System (SLS) launch vehicle (LV) is also presented due to it being a very critical aspect of the NCPS Human Mars Mission architecture due to the strong relationship between LV lift capability and LV volume capacity.

  6. Oxidative coupling of methane over supported La{sub 2}O{sub 3} and La-promoted MgO catalysts: Influence of catalyst-support interactions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Choudhary, V.R.; Mulla, S.A.R.; Uphade, B.S.

    1997-06-01

    Methane-to-C{sub 2}-hydrocarbon conversion activity and selectivity (or yield) of MgO and La-promoted MgO catalysts in the oxidative coupling of methane and strong basicity of the catalysts are decreased appreciably when these catalysts are deposited on commonly used commercial low surface area porous catalyst carriers containing Al{sub 2}O{sub 3}, SiO{sub 2}, SiC, or ZrO{sub 2} + HfO{sub 2} as the main components. The decrease in the strong basicity and catalytic activity/selectivity or yield is mostly due to strong chemical interactions between the active catalyst component (viz., MgO and La{sub 2}O{sub 3}) and the reactive components of the catalyst support (viz., Al{submore » 2}O{sub 3} and SiO{sub 2}), resulting in the formation of catalytically inactive binary metal oxides on the support surface. However, the influence of support on the activity/selectivity of La{sub 2}O{sub 3} is relatively very small, and also the chemical interactions of La{sub 2}O{sub 3} with the supports (except that containing a high concentration of SiO{sub 2}) are almost absent. The catalyst-support interactions are thus found to be strongly dependent upon the nature (chemical composition) of both catalyst and support. For developing better supported catalysts for the oxidative coupling of methane, supported La{sub 2}O{sub 3} with some promoters shows high promise.« less

  7. A work-centered cognitively based architecture for decision support: the work-centered infomediary layer (WIL) model

    NASA Astrophysics Data System (ADS)

    Zachary, Wayne; Eggleston, Robert; Donmoyer, Jason; Schremmer, Serge

    2003-09-01

    Decision-making is strongly shaped and influenced by the work context in which decisions are embedded. This suggests that decision support needs to be anchored by a model (implicit or explicit) of the work process, in contrast to traditional approaches that anchor decision support to either context free decision models (e.g., utility theory) or to detailed models of the external (e.g., battlespace) environment. An architecture for cognitively-based, work centered decision support called the Work-centered Informediary Layer (WIL) is presented. WIL separates decision support into three overall processes that build and dynamically maintain an explicit context model, use the context model to identify opportunities for decision support and tailor generic decision-support strategies to the current context and offer them to the system-user/decision-maker. The generic decision support strategies include such things as activity/attention aiding, decision process structuring, work performance support (selective, contextual automation), explanation/ elaboration, infosphere data retrieval, and what if/action-projection and visualization. A WIL-based application is a work-centered decision support layer that provides active support without intent inferencing, and that is cognitively based without requiring classical cognitive task analyses. Example WIL applications are detailed and discussed.

  8. The footprints of Saharan air layer and lightning on the formation of tropical depressions over the eastern Atlantic Ocean

    NASA Astrophysics Data System (ADS)

    Centeno Delgado, Diana C.; Chiao, Sen

    2015-02-01

    The roles of the Saharan Air Layer (SAL) and lightning during genesis of Tropical Depression (TD) 8 (2006) and TD 12 (2010) were investigated in relation to the interaction of the dust outbreaks with each system and their surrounding environment. This study applied data collected from the 2006 NASA African Monsoon Multidisciplinary Analysis and 2010 Genesis and Rapid Intensification Processes projects. Satellite observations from METEOSAT and Moderate Resolution Imaging Spectroradiometer (MODIS)—Aerosol Optical Depth (AOD) were also employed for the study of the dust content. Lightning activity data from the Met Office Arrival Time Difference (ATD) system were used as another parameter to correlate moist convective overturning and a sign of cyclone formation. The AOD and lightning analysis for TD 8 demonstrated the time-lag connection through their positive contribution to TC-genesis. TD 12 developed without strong dust outbreak, but with lower wind shear (2 m s-1) and an organized Mesoscale Convective System (MCS). Overall, the results from the combination of various data analyses in this study support the fact that both systems developed under either strong or weak dust conditions. From these two cases, the location (i.e., the target area) of strong versus weak dust outbreaks, in association with lightning, were essential interactions that impacted TC-genesis. While our dust footprints hypothesis applied under strong dust conditions (i.e., TD 8), other factors (e.g., vertical wind shear, pre-existing vortex and trough location, thermodynamics) need to be evaluated as well. The results from this study suggest that the SAL is not a determining factor that affects the formation of tropical cyclones (i.e., TD 8 and TD 12).

  9. PREFACE: Preface

    NASA Astrophysics Data System (ADS)

    Hotta, Takashi

    2016-02-01

    This volume of Journal of Physics: Conference Series contains both invited and contributed papers presented at the International Symposium on "New Quantum Phases Emerging from Novel Crystal Structure", which was held from 24-25 September 2015 at the Minami-Osawa Campus of Tokyo Metropolitan University (TMU). The Graduate School of Science and Engineering of TMU is now promoting a research project on "New Quantum Phases Emerging from Novel Crystal Structure" with the support of the university. This is the cooperative project involving the electrical and electronic engineering and physics departments to discover new quantum phases in strongly correlated electron systems on novel crystal structures, with geometrically characteristic properties such as cage, layered, and geometrical frustrated structures. In this international symposium, we have mainly picked up BiS2-based layered superconductors, cage-structure materials such as 1-2-20 and filled skutterudites, geometrically frustrated systems such as pyrochlore compounds, and noncentrosymmetric materials. Topics on other materials with exotic crystal structure have been also discussed. I believe that this symposium provides a good opportunity to present recent research results on magnetism and superconductivity in such materials, and to discuss future directions of research on strongly correlated electron systems with novel crystal structure. I would like to give thanks, on behalf of the organizing committee, to all participants of the TMU International Symposium and all members of the Advisory Committee, who have contributed to the success of this symposium. I further thank the TMU Research Organization for the financial support of this symposium.

  10. Potential advantages and disadvantages of an endgame strategy: a 'sinking lid' on tobacco supply.

    PubMed

    Wilson, Nick; Thomson, George W; Edwards, Richard; Blakely, Tony

    2013-05-01

    One possible supply-side strategy for the tobacco endgame is a government-mandated 'sinking lid' on tobacco supply (tradeable but decreasing quotas on sales or imports). We considered literature on quota systems and from a tobacco endgame workshop at the University of Michigan. Likely strengths of the sinking lid strategy include: (1) that it can provide a clear timetable and an unambiguous signal of a tobacco end-date; (2) that supply reduction is likely to increase product price levels, and there is very strong evidence that increasing price is a highly effective tobacco control intervention. Its feasibility is also supported by the growing international experience with, and political acceptability of, using quota and auction systems in other domains (eg, greenhouse gases, other air pollutants and for fisheries). However, the main disadvantages of this strategy are probably the need for strong political will and high public support (to pass a new law), potential legal challenges by industry (eg, under trade agreements), and vulnerability to problems from illegal supplies of tobacco and from corruption. The sinking lid strategy is a plausible option that is worth considering when investigating possible tobacco endgame strategies, though it may be most applicable in well-organised jurisdictions with low (<15%) adult smoking prevalence. This idea could benefit from further research, such as studies in virtual worlds, and real-world testing on small island jurisdictions, or closed systems, such as military bases.

  11. Potential advantages and disadvantages of an endgame strategy: a ‘sinking lid’ on tobacco supply

    PubMed Central

    Wilson, Nick; Thomson, George W; Edwards, Richard; Blakely, Tony

    2013-01-01

    Background One possible supply-side strategy for the tobacco endgame is a government-mandated ‘sinking lid’ on tobacco supply (tradeable but decreasing quotas on sales or imports). Methods We considered literature on quota systems and from a tobacco endgame workshop at the University of Michigan. Findings Likely strengths of the sinking lid strategy include: (1) that it can provide a clear timetable and an unambiguous signal of a tobacco end-date; (2) that supply reduction is likely to increase product price levels, and there is very strong evidence that increasing price is a highly effective tobacco control intervention. Its feasibility is also supported by the growing international experience with, and political acceptability of, using quota and auction systems in other domains (eg, greenhouse gases, other air pollutants and for fisheries). However, the main disadvantages of this strategy are probably the need for strong political will and high public support (to pass a new law), potential legal challenges by industry (eg, under trade agreements), and vulnerability to problems from illegal supplies of tobacco and from corruption. Conclusions The sinking lid strategy is a plausible option that is worth considering when investigating possible tobacco endgame strategies, though it may be most applicable in well-organised jurisdictions with low (<15%) adult smoking prevalence. This idea could benefit from further research, such as studies in virtual worlds, and real-world testing on small island jurisdictions, or closed systems, such as military bases. PMID:23591499

  12. The 2009 Health Confidence Survey: public opinion on health reform varies; strong support for insurance market reform and public plan option, mixed response to tax cap.

    PubMed

    Fronstin, Paul; Helman, Ruth

    2009-07-01

    PUBLIC SUPPORT FOR HEALTH REFORM: Findings from the 2009 Health Confidence Survey--the 12th annual HCS--indicate that Americans have already formed strong opinions regarding various aspects of health reform, even before details have been released regarding various key factors. These issues include health insurance market reform, the availability of a public plan option, mandates on employers and individuals, subsidized coverage for the low-income population, changes to the tax treatment of job-based health benefits, and regulatory oversight of health care. These opinions may change as details surface, especially as they concern financing options. In the absence of such details, the 2009 HCS finds generally strong support for the concepts of health reform options that are currently on the table. U.S. HEALTH SYSTEM GETS POOR MARKS, BUT SO DOES A MAJOR OVERHAUL: A majority rate the nation's health care system as fair (30 percent) or poor (29 percent). Only a small minority rate it excellent (6 percent) or very good (10 percent). While 14 percent of Americans think the health care system needs a major overhaul, 51 percent agree with the statement "there are some good things about our health care system, but major changes are needed." NATIONAL HEALTH PLAN ELEMENTS RATED HIGHLY: Between 68 percent and 88 percent of Americans either strongly or somewhat support health reform ideas such as national health plans, a public plan option, guaranteed issue, expansion of Medicare and Medicaid, and employer and individual mandates. MIXED REACTION TO HEALTH BENEFITS TAX CAP: Reaction to capping the current tax exclusion of employment-based health benefits is mixed. Nearly one-half of Americans (47 percent) would switch to a lower-cost plan if the tax exclusion were capped, 38 percent would stay on their current plan and pay the additional taxes, and 9 percent don't know. CONTINUED FAITH IN EMPLOYMENT-BASED BENEFITS, BUT DOUBTS ON AFFORDABILITY: Individuals with employment-based health benefits are confident that employers will continue to offer such benefits. They are much less confident that they would be able to afford coverage on their own, even if employers gave them the money they currently spend on health benefits. However, were employers to stop offering coverage, respondents report that they are likely to purchase it on their own. RISING HEALTH COSTS HURTING FAMILY FINANCES: Those experiencing health cost increases tend to say these increases have negatively affected their household finances. In particular, they indicate that increased health care costs have resulted in a decrease in contributions to a retirement plan (32 percent) and other savings (53 percent) and in difficulty paying for basic necessities (29 percent) and other bills (37 percent). COSTS ALSO AFFECTING HEALTH CARE USE: Many consumers report they are changing the way they use the health care system in response to rising health care costs. Roughly 80 percent of those with higher out-of-pocket expenses say these increased costs have led them to try to take better care of themselves and choose generic drugs more often. One-quarter also say they did not fill or skipped does of their prescribed medications in response to increased costs.

  13. Assessment of data quality and reporting systems for underserved populations: the case of integrated community case management programs in Nigeria.

    PubMed

    Nyangara, Florence M; Hai, Tajrina; Zalisk, Kirsten; Ozor, Lynda; Ufere, Joy; Isiguzo, Chinwoke; Abubakar, Ibrahim Ndaliman

    2018-05-01

    Decision makers are searching for reliable data and best practices to support the implementation and scale-up of the integrated community case management (iCCM) programs in underserved areas to reduce under-five mortality in low-income countries. This study assesses data quality and reporting systems of the World Health Organization supported Rapid Access Expansion program implementing iCCM in Abia and Niger States, Nigeria. This cross-sectional study used data from 16 primary health facilities in both states. Data were collected through review of registers and monthly summary reports of 140 community-oriented resource persons (CORPs), assessments of the five dimensions of the data reporting systems and 46 key informant interviews with stakeholders. Data quality was assessed by availability, completeness and consistency. Each component of the reporting system was assessed on a 3-point scale (weak, satisfactory and strong). Results show that both the structure, functions and capabilities, as well as data collection and reporting tools dimensions of the reporting system were strong, scoring (2.80, 2.73) for Abia and (2.88, 2.75) for Niger, respectively. Data management processes and links with national reporting system components scored low 2 s, indicating fair strength. Data availability, completeness and consistency were found to be good, an indication of adequate training and supervision of CORPs and community health extension workers. Indicator definitions and reporting guidelines were the weakest dimension of the system due to lack of data reporting guidelines in both states. In conclusion, the results indicate satisfactory data reporting systems and good quality data during early implementation of iCCM programs in the two states. Hence, countries planning to adopt and implement iCCM programs should first develop structures, establish national standardized tools for collecting and reporting data, provide for adequate training and supervision of community health workers and develop reporting guidelines for all reporting levels to ensure data quality.

  14. Sustainability of health information systems: a three-country qualitative study in southern Africa.

    PubMed

    Moucheraud, Corrina; Schwitters, Amee; Boudreaux, Chantelle; Giles, Denise; Kilmarx, Peter H; Ntolo, Ntolo; Bangani, Zwashe; St Louis, Michael E; Bossert, Thomas J

    2017-01-10

    Health information systems are central to strong health systems. They assist with patient and program management, quality improvement, disease surveillance, and strategic use of information. Many donors have worked to improve health information systems, particularly by supporting the introduction of electronic health information systems (EHIS), which are considered more responsive and more efficient than older, paper-based systems. As many donor-driven programs are increasing their focus on country ownership, sustainability of these investments is a key concern. This analysis explores the potential sustainability of EHIS investments in Malawi, Zambia and Zimbabwe, originally supported by the United States President's Emergency Plan for AIDS Relief (PEPFAR). Using a framework based on sustainability theories from the health systems literature, this analysis employs a qualitative case study methodology to highlight factors that may increase the likelihood that donor-supported initiatives will continue after the original support is modified or ends. Findings highlight commonalities around possible determinants of sustainability. The study found that there is great optimism about the potential for EHIS, but the perceived risks may result in hesitancy to transition completely and parallel use of paper-based systems. Full stakeholder engagement is likely to be crucial for sustainability, as well as integration with other activities within the health system and those funded by development partners. The literature suggests that a sustainable system has clearly-defined goals around which stakeholders can rally, but this has not been achieved in the systems studied. The study also found that technical resource constraints - affecting system usage, maintenance, upgrades and repairs - may limit EHIS sustainability even if these other pillars were addressed. The sustainability of EHIS faces many challenges, which could be addressed through systems' technical design, stakeholder coordination, and the building of organizational capacity to maintain and enhance such systems. All of this requires time and attention, but is likely to enhance long-term outcomes.

  15. Support afferentation in the posture and locomotion control system

    NASA Astrophysics Data System (ADS)

    Grigoriev, Anatoly; Tomilovskaya, Elena; Kozlovskaya, Inesa

    Mechanisms of support afferentation contribution in posture and locomotion control, which were uncertain up to now, became the point of intensive studies recently. This became possible since the space flights era started which created the conditions for simulated microgravity experiments under conditions of dry immersion and bedrest. The results of neurophysiological studies performed under the conditions of supportlessness have shown that decline or elimination of support loads is followed by deep and fast developing alterations in postural tonic system, including development of postural muscle atonia, changes of recruitment order of motoneurons innervating the shin muscles, spinal hyperreflexia development etc. (Kozlovskaya I.B. et al., 1987). It has been also shown that application of artificial support stimulation in the regimen of natural locomotion under these conditions decreases significantly or even eliminates the development of mentioned changes. The results of these studies laid down the basis for a new hypothesis on the trigger role of support afferentation in postural tonic system and its role in organization and control of postural synergies (Grigoriev A.I. et al., 2004). According to this hypothesis the muscle reception is considered to be the leading afferent input in the control of locomotion. However the data of recent studies pointed out strongly to the participation of support afferentation in definition of cognitive strategies and motor programs of locomotor movements (Chernikova L.A. et al., 2013) and, consequently, in the processes of their initiation (Gerasimenko Yu.P. et al., 2012). The cortical locomotor reflex composes apparently the basis of these processes. The receptive field of this reflex is located in the support zones of the soles and the central part is located in the posterior parietal areas (IPL) of brain cortex. The study is supported by RFBR grant N 13-04-12091 OFI-m.

  16. Detection of damaged supports under railway track based on frequency shift

    NASA Astrophysics Data System (ADS)

    Wang, Longqi; Zhang, Yao; Lie, Seng Tjhen

    2017-03-01

    In railway transportation systems, the tracks are usually fastened on sleepers which are supported by the ballast. A lot of research has been conducted to guarantee the safety of railway track because of its importance, and more concern is expressed about monitoring of track itself such as railway level and alignment. The ballast and fasteners which provide strong support to the railway track are important as well whereas the detection of loose or missing fasteners and damaged ballast mainly relies on visual inspection. Although it is reliable when the fastener is missing and the damaged ballast is on the surface, it provides less help if the fastener is only loose and the damaged ballast is under the sleepers, which are however frequently observed in practice. This paper proposes an approach based on frequency shift to identify the damaged supports including the loose or missing fasteners and damaged ballast. In this study, the rail-sleeper-ballast system is modeled as an Euler beam evenly supported by a series of springs, the stiffness of which are reduced when the fastener is loose or missing and the ballast under the sleepers is damaged. An auxiliary mass is utilized herein and when it is mounted on the beam, the natural frequencies of the whole system will change with respect to the location of the auxiliary mass. The auxiliary mass induced frequency shift is analyzed and it is found the natural frequencies change periodically when the supports are undamaged, whereas the periodicity will be broken due to damaged supports. In fact, the natural frequencies drop clearly when the auxiliary mass moves over the damaged support. A special damage index only using the information of the damaged states is proposed and both numerical and experimental examples are carried out to validate the proposed method.

  17. RTEMS Centre - Support and Maintenance Centre to RTEMS Operating System

    NASA Astrophysics Data System (ADS)

    Silva, H.; Constantino, A.; Freitas, D.; Coutinho, M.; Faustino, S.; Mota, M.; Colaço, P.; Sousa, J.; Dias, L.; Damjanovic, B.; Zulianello, M.; Rufino, J.

    2009-05-01

    RTEMS CENTRE - Support and Maintenance Centre to RTEMS Operating System is a joint ESA/Portuguese Task Force initiative to develop a support and maintenance centre to the Real-Time Executive for Multiprocessor Systems (RTEMS). This paper gives a high level visibility of the progress, the results obtained and the future work in the RTEMS CENTRE [6] and in the RTEMS Improvement [7] projects. RTEMS CENTRE started officially in November 2006, with the RTEMS 4.6.99.2 version. A full analysis of RTEMS operating system was produced. The architecture was analysed in terms of conceptual, organizational and operational concepts. The original objectives [1] of the centre were primarily to create and maintain technical expertise and competences in this RTOS, to develop a website to provide the European Space Community an entry point for obtaining support (http://rtemscentre.edisoft.pt), to design, develop, maintain and integrate some RTEMS support tools (Timeline Tool, Configuration and Management Tools), to maintain flight libraries and Board Support Packages, to develop a strong relationship with the World RTEMS Community and finally to produce some considerations in ARINC-653, DO-178B and ECSS E-40 standards. RTEMS Improvement is the continuation of the RTEMS CENTRE. Currently the RTEMS, version 4.8.0, is being facilitated for a future qualification. In this work, the validation material is being produced following the Galileo Software Standards Development Assurance Level B [5]. RTEMS is being completely tested, errors analysed, dead and deactivated code removed and tests produced to achieve 100% statement and decision coverage of source code [2]. The SW to exploit the LEON Memory Management Unit (MMU) hardware will be also added. A brief description of the expected implementations will be given.

  18. IRIS Toxicological Review of Methanol (Noncancer) (Revised External Review Draft)

    EPA Science Inventory

    EPA is seeking additional public comment and external peer review of the scientific basis supporting the human health hazard and dose-response assessment of methanol (noncancer).

  1. Systems Analysis - a new paradigm and decision support tools for the water framework directive

    NASA Astrophysics Data System (ADS)

    Bruen, M.

    2008-05-01

    In the early days of Systems Analysis the focus was on providing tools for optimisation, modelling and simulation for use by experts. Now there is a recognition of the need to develop and disseminate tools to assist in making decisions, negotiating compromises and communicating preferences that can easily be used by stakeholders without the need for specialist training. The Water Framework Directive (WFD) requires public participation and thus provides a strong incentive for progress in this direction. This paper places the new paradigm in the context of the classical one and discusses some of the new approaches which can be used in the implementation of the WFD. These include multi-criteria decision support methods suitable for environmental problems, adaptive management, cognitive mapping, social learning and cooperative design and group decision-making. Concordance methods (such as ELECTRE) and the Analytical Hierarchy Process (AHP) are identified as multi-criteria methods that can be readily integrated into Decision Support Systems (DSS) that deal with complex environmental issues with very many criteria, some of which are qualitative. The expanding use of the new paradigm provides an opportunity to observe and learn from the interaction of stakeholders with the new technology and to assess its effectiveness.

  2. Process membership in asynchronous environments

    NASA Technical Reports Server (NTRS)

    Ricciardi, Aleta M.; Birman, Kenneth P.

    1993-01-01

    The development of reliable distributed software is simplified by the ability to assume a fail-stop failure model. The emulation of such a model in an asynchronous distributed environment is discussed. The solution proposed, called Strong-GMP, can be supported through a highly efficient protocol, and was implemented as part of a distributed systems software project at Cornell University. The precise definition of the problem, the protocol, correctness proofs, and an analysis of costs are addressed.

  3. Comparative cytogenetics among populations of Astyanax altiparanae (Characiformes, Characidae, Incertae sedis)

    PubMed Central

    2009-01-01

    Cytogenetic data are presented for Astyanax altiparanae populations from three Brazilian hydrographic systems. The chromosomal data obtained in A. altiparanae support the hypothesis of diploid number conservation. However, small differences in the karyotype formula and number of nucleolar organizer regions were observed in these populations. The apparent karyotypical similarity among the studied populations strongly suggests a close relationship among them with some chromosomal divergences due to gene flow restriction. PMID:21637456

  4. Promoting Child Safety, Permanence, and Well-Being through Safe and Strong Families, Supportive Communities, and Effective Systems. Policy Matters: Setting and Measuring Benchmarks for State Policies. A Discussion Paper for the "Policy Matters" Project

    ERIC Educational Resources Information Center

    Center for the Study of Social Policy, 2009

    2009-01-01

    The "Policy Matters" project provides coherent, comprehensive information regarding the strength and adequacy of state policies affecting children, families, and communities. The project seeks to establish consensus among policy experts and state leaders regarding the mix of policies believed to offer the best opportunity for improving…

  5. Goals of Government-Funded Public Domain Software Efforts

    PubMed Central

    Rishel, Wesley J.

    1980-01-01

    The development of public domain software under Federal aegis and support has made possible a broadly competitive field of computer - oriented management information system consulting organizations with high technical competence and the potential for strong user orientation and loyalty. The impact of this assumption of major “front-end costs” by the Federal government has additional spin-off effects in terms of standardization and transportability features as well as reduced capital costs to the user.

  6. Wave Tank Studies of Strong Modulation of Wind Ripples Due To Long Waves

    NASA Astrophysics Data System (ADS)

    Ermakov, S.; Sergievskaya, I.; Shchegolkov, Yu.

    Modulation of wind capillary-gravity ripples due to long waves has been studied in wave tank experiment at low wind speeds using Ka-band radar. The experiments were carried out both for clean water and the water surface covered with surfactant films. It is obtained that the modulation of radar signals is quite strong and can increase with surfactant concentration and fetch. It is shown that the hydrodynamic Modulation Transfer Function (MTF) calculated for free wind ripples and taking into account the kinematic (straining) effect, variations of the wind stress and variations of surfactant concentration strongly underestimates experimental MTF-values. The effect of strong modulation is assumed to be connected with nonlinear harmonics of longer dm-cm- scale waves - bound waves ("parasitic ripples"). The intensity of bound waves depends strongly on the amplitude of decimetre-scale waves, therefore even weak modulation of the dm-scale waves due to long waves results to strong ("cascade") modulation of bound waves. Modulation of the system of "free/bound waves" is estimated using results of wave tank studies of bound waves generation and is shown to be in quali- tative agreement with experiment. This work was supported by MOD, UK via DERA Winfrith (Project ISTC 1774P) and by RFBR (Project 02-05-65102).

  7. Phylogenomic analyses of more than 4000 nuclear loci resolve the origin of snakes among lizard families.

    PubMed

    Streicher, Jeffrey W; Wiens, John J

    2017-09-01

    Squamate reptiles (lizards and snakes) are the most diverse group of terrestrial vertebrates, with more than 10 000 species. Despite considerable effort to resolve relationships among major squamates clades, some branches have remained difficult. Among the most vexing has been the placement of snakes among lizard families, with most studies yielding only weak support for the position of snakes. Furthermore, the placement of iguanian lizards has remained controversial. Here we used targeted sequence capture to obtain data from 4178 nuclear loci from ultraconserved elements from 32 squamate taxa (and five outgroups) including representatives of all major squamate groups. Using both concatenated and species-tree methods, we recover strong support for a sister relationship between iguanian and anguimorph lizards, with snakes strongly supported as the sister group of these two clades. These analyses strongly resolve the difficult placement of snakes within squamates and show overwhelming support for the contentious position of iguanians. More generally, we provide a strongly supported hypothesis of higher-level relationships in the most species-rich tetrapod clade using coalescent-based species-tree methods and approximately 100 times more loci than previous estimates. © 2017 The Author(s).

  8. Cosmic Microwave Background Timeline

    Science.gov Websites

    about 2.3 K 1948: George Gamow, Ralph Alpher, and Robert Herman predict that a Big Bang universe perfect blackbody spectrum and thereby strongly supporting the hot big bang model, the thermal history of anisotropy in the cosmic microwave background, this strongly supports the big bang model with gravitational

  9. Promoting research on research integrity in Canada.

    PubMed

    Master, Zubin; McDonald, Michael; Williams-Jones, Bryn

    2012-01-01

    Research on research integrity is an important element in building a strong national research integrity framework. There is a lack of empirical evidence and conceptual research on research integrity in Canada. To further strengthen and develop our system of research integrity, we believe that greater support is needed to promote research on research integrity. Research on research integrity is imperative in order to gain a richer understanding of the diversity of responsible conduct of research norms, practices, education and policies from a Canadian perspective. The knowledge gained would help in the development of an evidenced-based and responsive Canadian system of research integrity.

  10. A model structure for an EBM program in a multihospital system.

    PubMed

    Schumacher, Dale N; Stock, Joseph R; Richards, Joan K

    2003-01-01

    Evidence-based medicine (EBM) offers a great opportunity to translate advances in medical science into advances in clinical practice. We describe the structure of a comprehensive EBM program in a multihospital community teaching system. This EBM model is distinct and separate from the peer review process and has achieved substantial physician involvement. The program emanates from the Board of Directors Quality of Care Committee and has strong administrative support. The approach relies extensively on physician involvement and expert physician panels to enhance existing EBM practice guidelines, with an explicit strategy of performance reports and feedback.

  11. Many-body instabilities and mass generation in slow Dirac materials

    NASA Astrophysics Data System (ADS)

    Triola, Christopher; Zhu, Jianxin; Migliori, Albert; Balatsky, Alexander

    2015-03-01

    Some Kondo insulators are expected to possess topologically protected surface states with linear Dirac spectrum, the topological Kondo insulators. Because the bulk states of these systems typically have heavy effective electron masses, the surface states may exhibit extraordinarily small Fermi velocities that could force the effective fine structure constant of the surface states into the strong coupling regime. Using a tight-binding model we study the many-body instabilities of these systems and identify regions of parameter space for which antiferromagnetic, ferromagnetic and charge density wave instabilities occur. Work Supported by USDOE BES E304.

  12. Satellite Power System (SPS) military applications

    NASA Technical Reports Server (NTRS)

    Ozeroff, M. J.

    1978-01-01

    The potential military role, both offensive and defensive, of a Satellite Power System (SPS) is examined. A number of potential military support possibilities are described. An SPS with military capabilities may have a strong negative impact on international relations if it is not internationalized. The SPS satellite would be vulnerable to military action of an enemy with good space capability, but would experience little or no threat from saboteurs or terrorists, except via the ground controls. The paper concludes with an outline of some of the key issues involved, and a number of recommendations for future study, including some areas for long term efforts.

  13. Leadership for child health in the developing countries of the Western Pacific

    PubMed Central

    Subhi, Rami; Duke, Trevor

    2011-01-01

    The content and landscape of global child health is increasingly complex. There is strong evidence for the effectiveness of local, national and institutional leadership in reducing child mortality, but this has not been a focus of global health initiatives. Interventions to strengthen health systems should include support for local leadership: building-up institutions of training, empowering national paediatric professional associations, creating opportunities for contribution and leadership at national, provincial and local level, and networks of support for staff working in child health in remote areas. In the poorer high mortality burden countries of the Pacific, to meet the clinical and public health gaps, there is a need for increases in the education of child health nurse practitioners, and development of systems of continuing professional development for paediatric doctors and nurses. Involvement in local research, especially that which contributes directly to critical issues in child health policy or strengthening national data systems builds capacity for leadership. PMID:23198107

  14. Probing 1D superlattices at the LaAlO3 / SrTiO3 interface

    NASA Astrophysics Data System (ADS)

    Briggeman, M.; Huang, M.; Tylan-Tyler, A.; Irvin, P.; Levy, J.; Lee, J.-W.; Lee, H.; Eom, C.-B.

    Complex oxides and other quantum systems exhibit behavior that is currently too complex to be understood using analytic or computational methods. One approach is to use a configurable quantum system whose Hamiltonian can be mapped onto the system of interest. This approach, known as quantum simulation, requires a rich physical system whose quanta and interactions can be controlled precisely, at the level of single electrons and other degrees of freedom. Here we describe steps toward developing a quantum simulation platform, using the complex oxide heterostructure LaAlO3 / SrTiO3 , by creating quantum systems with features comparable to the mean spacing between electrons. This interface has strong, sign changing, gate-tunable electron-electron interactions that can strongly influence the quantum ground state. We explore the magnetotransport properties of 1D superlattices, where periodic modulation produces reproducible dispersive features not seen in control structures. The results of these experiments can be compared with effective 1D model Hamiltonians to bridge experiment and theory and enable quantum simulation of more complex systems. We gratefully acknowledge financial support from AFOSR (FA9550-12-1- 0057 (JL) and FA9550-12-1-0342 (CBE)), ONR N00014-15-1-2847 (JL), and NSF DMR-1234096 (CBE).

  15. Synthetic earthquake catalogs simulating seismic activity in the Corinth Gulf, Greece, fault system

    NASA Astrophysics Data System (ADS)

    Console, Rodolfo; Carluccio, Roberto; Papadimitriou, Eleftheria; Karakostas, Vassilis

    2015-01-01

    The characteristic earthquake hypothesis is the basis of time-dependent modeling of earthquake recurrence on major faults. However, the characteristic earthquake hypothesis is not strongly supported by observational data. Few fault segments have long historical or paleoseismic records of individually dated ruptures, and when data and parameter uncertainties are allowed for, the form of the recurrence distribution is difficult to establish. This is the case, for instance, of the Corinth Gulf Fault System (CGFS), for which documents about strong earthquakes exist for at least 2000 years, although they can be considered complete for M ≥ 6.0 only for the latest 300 years, during which only few characteristic earthquakes are reported for individual fault segments. The use of a physics-based earthquake simulator has allowed the production of catalogs lasting 100,000 years and containing more than 500,000 events of magnitudes ≥ 4.0. The main features of our simulation algorithm are (1) an average slip rate released by earthquakes for every single segment in the investigated fault system, (2) heuristic procedures for rupture growth and stop, leading to a self-organized earthquake magnitude distribution, (3) the interaction between earthquake sources, and (4) the effect of minor earthquakes in redistributing stress. The application of our simulation algorithm to the CGFS has shown realistic features in time, space, and magnitude behavior of the seismicity. These features include long-term periodicity of strong earthquakes, short-term clustering of both strong and smaller events, and a realistic earthquake magnitude distribution departing from the Gutenberg-Richter distribution in the higher-magnitude range.

  16. NSTX-U Control System Upgrades

    DOE PAGES

    Erickson, K. G.; Gates, D. A.; Gerhardt, S. P.; ...

    2014-06-01

    The National Spherical Tokamak Experiment (NSTX) is undergoing a wealth of upgrades (NSTX-U). These upgrades, especially including an elongated pulse length, require broad changes to the control system that has served NSTX well. A new fiber serial Front Panel Data Port input and output (I/O) stream will supersede the aging copper parallel version. Driver support for the new I/O and cyber security concerns require updating the operating system from Redhat Enterprise Linux (RHEL) v4 to RedHawk (based on RHEL) v6. While the basic control system continues to use the General Atomics Plasma Control System (GA PCS), the effort to forwardmore » port the entire software package to run under 64-bit Linux instead of 32-bit Linux included PCS modifications subsequently shared with GA and other PCS users. Software updates focused on three key areas: (1) code modernization through coding standards (C99/C11), (2) code portability and maintainability through use of the GA PCS code generator, and (3) support of 64-bit platforms. Central to the control system upgrade is the use of a complete real time (RT) Linux platform provided by Concurrent Computer Corporation, consisting of a computer (iHawk), an operating system and drivers (RedHawk), and RT tools (NightStar). Strong vendor support coupled with an extensive RT toolset influenced this decision. The new real-time Linux platform, I/O, and software engineering will foster enhanced capability and performance for NSTX-U plasma control.« less

  17. Transformation impacts of dissolved and solid phase Fe(II) on trichloroethylene (TCE) reduction in an iron-reducing bacteria (IRB) mixed column system: a mathematical model.

    PubMed

    Bae, Yeunook; Kim, Dooil; Cho, Hyun-Hee; Singhal, Naresh; Park, Jae-Woo

    2012-12-01

    In this research, we conducted trichloroethylene (TCE) reduction in a column filled with iron and iron-reducing bacteria (IRB) and developed a mathematical model to investigate the critical reactions between active species in iron/IRB/contaminant systems. The formation of ferrous iron (Fe(II)) in this system with IRB and zero-valent iron (ZVI, Fe(0)) coated with a ferric iron (Fe(III)) crust significantly affected TCE reduction and IRB respiration in various ways. This study presents a new framework for transformation property and reducing ability of both dissolved (Fe(II)(dissolved)) and solid form ferrous iron (Fe(II)(solid)). Results showed that TCE reduction was strongly depressed by Fe(II)(solid) rather than by other inhibitors (e.g., Fe(III) and lactate), suggesting that Fe(II)(solid) might reduce IRB activation due to attachment to IRB cells. Newly exposed Fe(0) from the released Fe(II)(dissolved) was a strong contributor to TCE reduction compared to Fe(II)(solid). In addition, our research confirmed that less Fe(II)(solid) production strongly supported long-term TCE reduction because it may create an easier TCE approach to Fe(0) or increase IRB growth. Our findings will aid the understanding of the contributions of iron media (e.g., Fe(II)(solid), Fe(II)(dissolved), Fe(III), and Fe(0)) to IRB for decontamination in natural groundwater systems. Copyright © 2012 Elsevier Ltd. All rights reserved.

  18. Fluid management in the optimization of space construction

    NASA Technical Reports Server (NTRS)

    Snyder, Howard

    1990-01-01

    Fluid management impacts strongly on the optimization of space construction. Large quantities of liquids are needed for propellants and life support. The mass of propellant liquids is comparable to that required for the structures. There may be a strong dynamic interaction between the stored liquids and the space structure unless the design minimizes the interaction. The constraints of cost and time required optimization of the supply/resupply strategy. The proper selection and design of the fluid management methods for: slosh control; stratification control; acquisition; transfer; gauging; venting; dumping; contamination control; selection of tank configuration and size; the storage state and the control system can improve the entire system performance substantially. Our effort consists of building mathematical/computer models of the various fluid management methods and testing them against the available experimental data. The results of the models are used as inputs to the system operations studies. During the past year, the emphasis has been on modeling: the transfer of cryogens; sloshing and the storage configuration. The work has been intermeshed with ongoing NASA design and development studies to leverage the funds provided by the Center.

  19. Communication-and-resolution programs: the challenges and lessons learned from six early adopters.

    PubMed

    Mello, Michelle M; Boothman, Richard C; McDonald, Timothy; Driver, Jeffrey; Lembitz, Alan; Bouwmeester, Darren; Dunlap, Benjamin; Gallagher, Thomas

    2014-01-01

    In communication-and-resolution programs (CRPs), health systems and liability insurers encourage the disclosure of unanticipated care outcomes to affected patients and proactively seek resolutions, including offering an apology, an explanation, and, where appropriate, reimbursement or compensation. Anecdotal reports from the University of Michigan Health System and other early adopters of CRPs suggest that these programs can substantially reduce liability costs and improve patient safety. But little is known about how these early programs achieved success. We studied six CRPs to identify the major challenges in and lessons learned from implementing these initiatives. The CRP participants we interviewed identified several factors that contributed to their programs' success, including the presence of a strong institutional champion, investing in building and marketing the program to skeptical clinicians, and making it clear that the results of such transformative change will take time. Many of the early CRP adopters we interviewed expressed support for broader experimentation with these programs even in settings that differ from their own, such as systems that do not own and control their liability insurer, and in states without strong tort reforms.

  20. Aging in the Third World.

    PubMed

    Hugo, G

    1987-01-01

    The relationships between the generations in Third World countries are changing as migration and industrialization erode traditional family responsibilities for supporting the elderly. It is no longer possible to assume that, as a matter of course, old people will be looked after by their families. Social change leads to an eroding of the support systems. The author finds growing evidence of this breakdown in Asia, particularly in Singapore, Hong Kong, and other highly industrialized centers. Singapore, for example, has reinstituted the compulsory study of filial piety in an attempt to push the younger generation into assuming its traditional responsibility toward the old. There has also been a significant decline in the status, prestige, and support given old people in Indonesia, although politicans insist that the family will always take care of its elderly. 2 reasons for this breakdown are 1) the impact of the mass media and 2) the increasing involvement of the younger generation in non-agricultural jobs which often involve a move to the city and away from dependence on a patriarch. Many Third World countries are in a twilight stage, between the traditionally strong structure of family support and government systems of social security.

  1. Oral Health and Erectile Dysfunction.

    PubMed

    Singh, Vijendra P; Nettemu, Sunil K; Nettem, Sowmya; Hosadurga, Rajesh; Nayak, Sangeeta U

    2017-01-01

    Ample evidence strongly supports the fact that periodontal disease is a major risk factor for various systemic diseases namely cardio-vascular disease, diabetes mellitus, etc. Recently, investigators focussed on exploring the link between chronic periodontitis (CP) and erectile dysfunction (ED) by contributing to the endothelial dysfunction. Both the diseases share common risk factors. Various studies conducted in different parts of the world in recent years reported the evidence linking this relationship as well as improvement in ED with periodontal treatment. Systemic exposure to the periodontal pathogen and periodontal infection-induced systemic inflammation was thought to associate with these conditions. The objective of this review was to highlight the evidence of the link between CP and ED and the importance of oral health in preventing the systemic conditions.

  2. Oral Health and Erectile Dysfunction

    PubMed Central

    Singh, Vijendra P.; Nettemu, Sunil K.; Nettem, Sowmya; Hosadurga, Rajesh; Nayak, Sangeeta U.

    2017-01-01

    Ample evidence strongly supports the fact that periodontal disease is a major risk factor for various systemic diseases namely cardio-vascular disease, diabetes mellitus, etc. Recently, investigators focussed on exploring the link between chronic periodontitis (CP) and erectile dysfunction (ED) by contributing to the endothelial dysfunction. Both the diseases share common risk factors. Various studies conducted in different parts of the world in recent years reported the evidence linking this relationship as well as improvement in ED with periodontal treatment. Systemic exposure to the periodontal pathogen and periodontal infection-induced systemic inflammation was thought to associate with these conditions. The objective of this review was to highlight the evidence of the link between CP and ED and the importance of oral health in preventing the systemic conditions. PMID:29142443

  3. Breastfeeding protection, promotion, and support in the United States: a time to nudge, a time to measure.

    PubMed

    Pérez-Escamilla, Rafael; Chapman, Donna J

    2012-05-01

    Strong evidence-based advocacy efforts have now translated into high level political support and concrete goals for improving breastfeeding outcomes among women in the United States. In spite of this, major challenge remain for promoting, supporting and especially for protecting breastfeeding in the country. The goals of this commentary are to argue in favor of: A) Changes in the default social and environmental systems, that would allow women to implement their right to breastfeed their infants, B) A multi-level and comprehensive monitoring system to measure process and outcomes indicators in the country. Evidence-based commentary. Breastfeeding rates in the United States can improve based on a well coordinated social marketing framework. This approach calls for innovative promotion through mass media, appropriate facility based and community based support (e.g., Baby Friendly Hospital Initiative, WIC-coordinated community based peer counseling), and adequate protection for working women (e.g., longer paid maternity leave, breastfeeding or breast milk extraction breaks during the working day) and women at large by adhering and enforcing the WHO ethics Code for the Marketing of Breast Milk Substitutes. Sound infant feeding practices monitoring systems, which include WIC administrative food package data, are needed. Given the current high level of political support to improve breastfeeding in the United States, a window of opportunity has been opened. Establishing breastfeeding as the social norm in the USA will take time, but the global experience indicates that it can be done.

  4. Logistics Reduction and Repurposing Beyond Low Earth Orbit

    NASA Technical Reports Server (NTRS)

    Ewert, Michael K.; Broyan, James L., Jr.

    2012-01-01

    All human space missions, regardless of destination, require significant logistical mass and volume that is strongly proportional to mission duration. Anything that can be done to reduce initial mass and volume of supplies or reuse items that have been launched will be very valuable. Often, the logistical items require disposal and represent a trash burden. Logistics contributions to total mission architecture mass can be minimized by considering potential reuse using systems engineering analysis. In NASA's Advanced Exploration Systems "Logistics Reduction and Repurposing Project," various tasks will reduce the intrinsic mass of logistical packaging, enable reuse and repurposing of logistical packaging and carriers for other habitation, life support, crew health, and propulsion functions, and reduce or eliminate the nuisance aspects of trash at the same time. Repurposing reduces the trash burden and eliminates the need for hardware whose function can be provided by use of spent logistical items. However, these reuse functions need to be identified and built into future logical systems to enable them to effectively have a secondary function. These technologies and innovations will help future logistics systems to support multiple exploration missions much more efficiently.

  5. Atmospheric dynamics and bioregenerative technologies in a soil-based ecological life support system: Initial results from biosphere 2

    NASA Astrophysics Data System (ADS)

    Nelson, M.; Dempster, W.; Alvarez-Romo, N.; MacCallum, T.

    1994-11-01

    Biosphere 2 is the first man-made, soil-based, bioregenerative life support system to be developed and tested. The utilization and amendment of local space resources, e.g. martian soil or lunar regolith, for agricultural and other purposes will be necesary if we are to minimize the requirement for Earth materials in the creation of long-term off-planet bases and habitations. Several of the roles soil plays in Biosphere 2 are 1) for air purification 2) as a key component in created wetland systems to recycle human and animal wastes and 3) as nutrient base for a sustainable agricultural cropping program. Initial results from the Biosphere 2 closure experiment are presented. These include the accelerated cycling rates due to small reservoir sizes, strong diurnal and seasonal fluxes in atmospheric CO2, an unexpected and continuing decline in atmospheric oxygen, overall maintenance of low levels of trace gases, recycling of waste waters through biological regeneration systems, and operation of an agriculture designed to provide diverse and nutritionally adequate diets for the crew members.

  6. Health Information Technology Systems profoundly impact users: a case study in a dental school.

    PubMed

    Hill, Heather K; Stewart, Denice C L; Ash, Joan S

    2010-04-01

    The purpose of this study was to increase our understanding of the impact of Health Information Technology Systems (HITS) on dental school users when the systems are integrated into chair-side patient care. We used qualitative research methods, including interviews, focus groups, and observations, to capture the experiences of HITS users at a single institution. Users included administrators, clinical faculty members, predoctoral students, support staff, and residents. The data were analyzed using a grounded theory approach, and nine themes emerged: 1) HITS benefits were disproportionate among users; 2) communicating about the HITS was challenging; 3) users experienced a range of strong emotions; 4) the instructor persona diminished; 5) there were shifts in the school's power structure; 6) allocation of end-users' time shifted; 7) the training and support needs of end-users were significant; 8) perceived lack of HITS usability made documentation cumbersome for clinicians; and 9) clinicians' workflow was disrupted. HITS integration into patient care impacts the work of all system users, especially end-users. The themes highlight areas of potential concern for implementers and users in integrating a HITS into patient care.

  7. Dual-band plasmonic resonator based on Jerusalem cross-shaped nanoapertures

    NASA Astrophysics Data System (ADS)

    Cetin, Arif E.; Kaya, Sabri; Mertiri, Alket; Aslan, Ekin; Erramilli, Shyamsunder; Altug, Hatice; Turkmen, Mustafa

    2015-06-01

    In this paper, we both experimentally and numerically introduce a dual-resonant metamaterial based on subwavelength Jerusalem cross-shaped apertures. We numerically investigate the physical origin of the dual-resonant behavior, originating from the constituting aperture elements, through finite difference time domain calculations. Our numerical calculations show that at the dual-resonances, the aperture system supports large and easily accessible local electromagnetic fields. In order to experimentally realize the aperture system, we utilize a high-precision and lift-off free fabrication method based on electron-beam lithography. We also introduce a fine-tuning mechanism for controlling the dual-resonant spectral response through geometrical device parameters. Finally, we show the aperture system's highly advantageous far- and near-field characteristics through numerical calculations on refractive index sensitivity. The quantitative analyses on the availability of the local fields supported by the aperture system are employed to explain the grounds behind the sensitivity of each spectral feature within the dual-resonant behavior. Possessing dual-resonances with large and accessible electromagnetic fields, Jerusalem cross-shaped apertures can be highly advantageous for wide range of applications demanding multiple spectral features with strong nearfield characteristics.

  8. [Dominating motivation in systemic memory mechanisms].

    PubMed

    Sudakov, K V

    2005-01-01

    The materials provided in the article support the key role of dominating motivation in the systemic processes of fixation and opening of memory mechanisms. The activating mechanisms of dominating motivations in the systemic architectonics of behavioural acts provide the basis for development of a multicomponent acceptor apparatus of an action outcomes broadly represented in various analysing brain sections. As result of enhancement of action outcomes on acceptors structures, molecular behaviour engrammes form within the functional systems. It is these molecular engrammes that are opened by dominating motivations in the same spatial-temporal sequence in which training takes place, and determine deliberate actions of animals. It was demonstrated that dominating motivation opens genetic information with an approximating-exploratory reaction under strong activation of early genes expression, in particular, of c-fos gene protein. Inherent motivation reactions are not blocked by inhibitors of proteins synthesis, by cycloheximide, in particular. In the process of training animals, i.e., satisfaction of the demands which are the basis of dominating motivations, expression of early genes in reduced, while expression of late genes is initiated. In this case, blockators of protein synthesis begin to produce strong inhibiting impact on behaviour of animals.

  9. Rethinking niche evolution: experiments with natural communities of Protozoa in pitcher plants.

    PubMed

    Miller, Thomas E; Moran, Emma R; terHorst, Casey P

    2014-08-01

    Classic niche theory predicts that competing species will evolve to use different resources and interact less, whereas recent niche-converge ideas predict that species evolve to use similar resources and interact more. Most data supporting niche evolution are based on observations of contemporary niche use, whereas experimental support is quite sparse. We followed the evolution of four species of Protozoa during succession in the water-filled leaves of the pitcher plant, Sarracenia purpurea, and found that evolution in multispecies systems follows a surprising pattern. Over several hundred generations, weak competitors evolved to be stronger, while strong competitors evolved to become weaker, which does not conform to expectations of either niche divergence or convergence. Evolution in this system appears to occur in response to characteristics of a suite of several competitors in the community, rather than pairwise interactions. Ecologists may need to rethink the roles of competition and evolution in structuring communities.

  10. NextGEOSS: The Next Generation Data Hub For Earth Observations

    NASA Astrophysics Data System (ADS)

    Lilja Bye, Bente; De Lathouwer, Bart; Catarino, Nuno; Concalves, Pedro; Trijssenaar, Nicky; Grosso, Nuno; Meyer-Arnek, Julian; Goor, Erwin

    2017-04-01

    The Group on Earth observation embarked on the next 10 year phase with an ambition to streamline and further develop its achievements in building the Global Earth Observing System of Systems (GEOSS). The NextGEOSS project evolves the European vision of GEOSS data exploitation for innovation and business, relying on the three main pillars of engaging communities, delivering technological developments and advocating the use of GEOSS, in order to support the creation and deployment of Earth observation based innovative research activities and commercial services. In this presentation we will present the NextGEOSS concept, a concept that revolves around providing the data and resources to the users communities, together with Cloud resources, seamlessly connected to provide an integrated ecosystem for supporting applications. A central component of NextGEOSS is the strong emphasis put on engaging the communities of providers and users, and bridging the space in between.

  11. Spatial decision support system for tobacco enterprise based on spatial data mining

    NASA Astrophysics Data System (ADS)

    Mei, Xin; Liu, Junyi; Zhang, Xuexia; Cui, Weihong

    2007-11-01

    Tobacco enterprise is a special enterprise, which has strong correlation to regional geography. But in the past research and application, the combination between tobacco and GIS is limited to use digital maps to assist cigarette distribution. How to comprehensively import 3S technique and spatial data mining (SDM) to construct spatial decision support system (SDSS) of tobacco enterprise is the main research aspect in this paper. The paper concretely analyzes the GIS requirements in tobacco enterprise for planning location of production, monitoring production management and product sale at the beginning. Then holistic solution is presented and frame design for tobacco enterprise spatial decision based on SDM is given. This paper describes how to use spatial analysis and data mining to realize the spatial decision processing such as monitoring tobacco planted acreage, analyzing and planning the cigarette sale network and so on.

  12. Clinical Decision Support: Effectiveness in Improving Quality Processes and Clinical Outcomes and Factors That May Influence Success

    PubMed Central

    Murphy, Elizabeth V.

    2014-01-01

    The use of electronic health records has skyrocketed following the 2009 HITECH Act, which provides financial incentives to health care providers for the “meaningful use” of electronic medical record systems. An important component of the “Meaningful Use” legislation is the integration of Clinical Decision Support Systems (CDSS) into the computerized record, providing up-to-date medical knowledge and evidence-based guidance to the physician at the point of care. As reimbursement is increasingly tied to process and clinical outcomes, CDSS will be integral to future medical practice. Studies of CDSS indicate improvement in preventive services, appropriate care, and clinical and cost outcomes with strong evidence for CDSS effectiveness in process measures. Increasing provider adherence to CDSS recommendations is essential in improving CDSS effectiveness, and factors that influence adherence are currently under study. PMID:24910564

  13. HIV-Related Sexual Risk among African American Men Preceding Incarceration: Associations with Support from Significant Others, Family, and Friends.

    PubMed

    Coatsworth, Ashley M; Scheidell, Joy D; Wohl, David A; Whitehead, Nicole E; Golin, Carol E; Judon-Monk, Selena; Khan, Maria R

    2017-02-01

    We evaluated the association between social support received from significant others, family, and friends and HIV-related sexual risk behaviors among African American men involved in the criminal justice system. Project DISRUPT is a cohort study among African American men released from prison in North Carolina (N = 189). During the baseline (in-prison) survey, we assessed the amount of support men perceived they had received from significant others, family, and friends. We measured associations between low support from each source (

  14. Exposure to tobacco marketing and support for tobacco control policies.

    PubMed

    Hammond, David; Costello, Mary-Jean; Fong, Geoffrey T; Topham, Jennifer

    2006-01-01

    To examine the salience of tobacco marketing on postsecondary campuses and student support for tobacco control policies. Face-to-face surveys were conducted with 1690 students at 3 universities in southwestern Ontario. Virtually all (97%) students reported noticing tobacco marketing in the past year, and 35% reported noticing marketing on campus. There was strong support for smoke-free restrictions on campus, including restaurants and bars (82%), and for prohibitions on campus marketing. The presence of campus policies was associated with reduced exposure to marketing and increased policy support. There is strong support among students to remove tobacco marketing from campus and to introduce comprehensive smoke-free restrictions.

  15. Bringing It All Together: The Multiple Origins, Skills, and Environmental Supports of Early Literacy.

    ERIC Educational Resources Information Center

    Dickinson, David K.; McCabe, Allyssa

    2001-01-01

    Data from three studies investigating factors supporting literacy development of children from low-income families indicate: early levels of achievement are strongly linked to later success; kindergarten vocabulary is strongly reflective of the use of varied vocabulary during meal times; and teacher training in literacy is beneficial to classroom…

  16. Social support patterns of collegiate athletes before and after injury.

    PubMed

    Yang, Jingzhen; Peek-Asa, Corinne; Lowe, John B; Heiden, Erin; Foster, Danny T

    2010-01-01

    Social support has been identified as an important factor in facilitating recovery from injury. However, no previous authors have prospectively assessed the change in social support patterns before and after injury. To examine the preinjury and postinjury social support patterns among male and female collegiate athletes. Prospective observational study. A Big Ten Conference university. A total of 256 National Collegiate Athletic Association Division I male and female collegiate athletes aged 18 or older from 13 sports teams. Injury incidence was identified using the Sports Injury Monitoring System. Social support was measured using the 6-item Social Support Questionnaire. Data on preinjury and postinjury social support patterns were compared. Male athletes reported more sources of social support than female athletes, whereas female athletes had greater satisfaction with the support they received. Athletes' social support patterns changed after they became injured. Injured athletes reported relying more on coaches (P = .003), athletic trainers (P < .0001), and physicians (P = .003) for social support after they became injured. Athletes also reported greater postinjury satisfaction with social support received from friends (P = .019), coaches (P = .001), athletic trainers (P < .0001), and physicians (P = .003). Our findings identify an urgent need to better define the psychosocial needs of injured athletes and also strongly suggest that athletic trainers have a critical role in meeting these needs.

  17. Systems Architecture for a Nationwide Healthcare System.

    PubMed

    Abin, Jorge; Nemeth, Horacio; Friedmann, Ignacio

    2015-01-01

    From a national level to give Internet technology support, the Nationwide Integrated Healthcare System in Uruguay requires a model of Information Systems Architecture. This system has multiple healthcare providers (public and private), and a strong component of supplementary services. Thus, the data processing system should have an architecture that considers this fact, while integrating the central services provided by the Ministry of Public Health. The national electronic health record, as well as other related data processing systems, should be based on this architecture. The architecture model described here conceptualizes a federated framework of electronic health record systems, according to the IHE affinity model, HL7 standards, local standards on interoperability and security, as well as technical advice provided by AGESIC. It is the outcome of the research done by AGESIC and Systems Integration Laboratory (LINS) on the development and use of the e-Government Platform since 2008, as well as the research done by the team Salud.uy since 2013.

  18. Space station integrated propulsion and fluid systems study

    NASA Technical Reports Server (NTRS)

    Bicknell, B.; Wilson, S.; Dennis, M.; Shepard, D.; Rossier, R.

    1988-01-01

    The program study was performed in two tasks: Task 1 addressed propulsion systems and Task 2 addressed all fluid systems associated with the Space Station elements, which also included propulsion and pressurant systems. Program results indicated a substantial reduction in life cycle costs through integrating the oxygen/hydrogen propulsion system with the environmental control and life support system, and through supplying nitrogen in a cryogenic gaseous supercritical or subcritical liquid state. A water sensitivity analysis showed that increasing the food water content would substantially increase the amount of water available for propulsion use and in all cases, the implementation of the BOSCH CO2 reduction process would reduce overall life cycle costs to the station and minimize risk. An investigation of fluid systems and associated requirements revealed a delicate balance between the individual propulsion and fluid systems across work packages and a strong interdependence between all other fluid systems.

  19. Room-temperature cavity quantum electrodynamics with strongly coupled Dicke states

    NASA Astrophysics Data System (ADS)

    Breeze, Jonathan D.; Salvadori, Enrico; Sathian, Juna; Alford, Neil McN.; Kay, Christopher W. M.

    2017-09-01

    The strong coupling regime is essential for efficient transfer of excitations between states in different quantum systems on timescales shorter than their lifetimes. The coupling of single spins to microwave photons is very weak but can be enhanced by increasing the local density of states by reducing the magnetic mode volume of the cavity. In practice, it is difficult to achieve both small cavity mode volume and low cavity decay rate, so superconducting metals are often employed at cryogenic temperatures. For an ensembles of N spins, the spin-photon coupling can be enhanced by √{N } through collective spin excitations known as Dicke states. For sufficiently large N the collective spin-photon coupling can exceed both the spin decoherence and cavity decay rates, making the strong-coupling regime accessible. Here we demonstrate strong coupling and cavity quantum electrodynamics in a solid-state system at room-temperature. We generate an inverted spin-ensemble with N 1015 by photo-exciting pentacene molecules into spin-triplet states with spin dephasing time T2* 3 μs. When coupled to a 1.45 GHz TE01δ mode supported by a high Purcell factor strontium titanate dielectric cavity (Vm 0.25 cm3, Q 8,500), we observe Rabi oscillations in the microwave emission from collective Dicke states and a 1.8 MHz normal-mode splitting of the resultant collective spin-photon polariton. We also observe a cavity protection effect at the onset of the strong-coupling regime which decreases the polariton decay rate as the collective coupling increases.

  20. Numerical Simulation of Nocturnal Drainage Flows in Idealized Valley-Tributary Systems.

    NASA Astrophysics Data System (ADS)

    O'Steen, Lance B.

    2000-11-01

    Numerical simulations of nocturnal drainage flow and transport in idealized valley-tributary systems are compared with the Atmospheric Science in Complex Terrain (ASCOT) meteorological field data and tracer studies from the Brush Creek valley of western Colorado. Much of the general valley-tributary flow behavior deduced from observations is qualitatively reproduced in the numerical results. The spatially complex, unsteady nature of the tributary flow found in the field data is also seen in the simulations. Oscillations in the simulated tributary flow are similar to some field observations. However, observed oscillations in the valley flow at the mouth of the tributary could not be reproduced in the numerical results. Thus, hypotheses of strongly coupled valley-tributary flow oscillations, based on field data, cannot be supported by these simulations. Along-valley mass flux calculations based on model results for the valley-tributary system indicate an increase of 5%-10% over a valley without a tributary. Enhanced valley mass fluxes were found from 8 km above the tributary to almost the valley mouth. However, the valley mass fluxes for topography with and without a tributary were nearly equal at the valley outflow. ASCOT field data suggested a tributary mass flow contribution of 5%-15% for a Brush Creek tributary of similar drainage area to the model tributary employed here. Numerical simulations of transport in the nocturnal valley-tributary flow strongly support ASCOT tracer studies in the Pack Canyon tributary of Brush Creek. These results suggest that the valley-tributary interaction can significantly increase plume dispersion under stable conditions. Overall, the simulation results presented here indicate that simple terrain geometries are able to capture many of the salient features of drainage flow in real valley-tributary systems.

  1. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Han, Chang Wan; Choksi, Tej; Milligan, Cory

    The strength of metal-support bonding in heterogeneous catalysts determines their thermal stability, therefore, a tremendous amount of effort has been expended to understand metal-support interactions. Herein, we report the discovery of an anomalous “strong metal-support bonding” between gold nanoparticles and “nano-engineered” Fe 3O 4 substrates by in-situ microscopy. During in-situ vacuum annealing of Au-Fe 3O 4 dumbbell-like nanoparticles, synthesized by the epitaxial growth of nano-Fe 3O 4 on Au nanoparticles, the gold nanoparticles transform into the monolayered gold thinfilms and wet the surface of nano-Fe 3O 4, as the surface reduction of nano-Fe 3O 4 proceeds. This phenomenon results frommore » a unique coupling of the size-and shape-dependent high surface reducibility of nano-Fe 3O 4 and the extremely strong adhesion between Au and the reduced Fe 3O 4. This strong-metal support bonding reveals the significance of controlling the metal oxide support size and morphology for optimizing metal-support bonding and, ultimately, for the development of improved catalysts and functional nanostructures.« less

  2. Satellite power system (SPS) military implications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bain, C.N.

    1978-10-01

    This study was conducted to examine military implications of the NASA Reference SPS and to identify important military related study tasks that could be completed during fiscal year 1979. Primary areas of investigation were the potential of the SPS as a weapon, for supporting U.S. military preparedness and for affecting international relations. In addition, the SPS's relative vulnerability to overt military action, terrorist attacks, and sabotage was considered. The SPS could act as an electronic warfare weapon and, with modification, as a marginally effective energy-beaming weapon. The system could support military preparedness by providing energy for a strong and stablemore » U.S. economy and by providing a powered platform for military systems, system segments, and operations. The SPS would be vulnerable to military action, terrorism and sabotage unless hardened against these attacks by design, security, and a self-defense system. Tasks identified for completion in fiscal year 1979 include (a) a detailed vulnerability study, (b) evaluation of an SPS self-defense system concept, (c) determination of the effect of SPS flexibility to deliver different sized electrical loads on the ability to gain SPS support from individual nations, and (d) investigation of the effect of SPS deployment schedule on obtaining needed agreements, providing security, and controlling risks of armed conflict. A fifth and long-term task would consist of a worldwide survey identifiying military implications of the SPS that result from the specific requirements of potential SPS power customers.« less

  3. The fine structure of the terminal segment of the bovine seminiferous tubule.

    PubMed

    Wrobel, K H; Sinowatz, F; Mademann, R

    1982-01-01

    The intratesticular excurrent duct system of the bull is composed of rete testis, tubuli recti, and the terminal segment of the seminiferous tubules. Each terminal segment is surrounded by a vascular plexus and may be subdivided into a transitional region, middle portion, and terminal plug. The modified supporting cells of the middle portion and the terminal plug no longer display the typical Sertoli-Sertoli junctions seen in the transitional region and the seminiferous tubule proper. In the region of the terminal plug a distinct central lumen is generally not observed: spermatozoa and tubular fluid must pass through an intricate system of communicating clefts between the apices of the closely attached modified supporting cells. Vacuoles in the supranuclear region of the cells in the middle portion indicate strong transepithelial fluid transport. In analogy to the epithelium of rete testis and tubuli recti, the supporting cells of the terminal segment are capable of phagocytosing spermatozoa. The vascular plexus investing the terminal segment serves a dual purpose: it is a regulatory device for fluid and sperm transport, as well as an area of increased diapedesis for white blood cells.

  4. Strong evidence for terrestrial support of zooplankton in small lakes based on stable isotopes of carbon, nitrogen, and hydrogen

    USGS Publications Warehouse

    Cole, J.J.; Carpenter, S.R.; Kitchell, J.; Pace, M.L.; Solomon, C.T.; Weidel, B.

    2011-01-01

    Cross-ecosystem subsidies to food webs can alter metabolic balances in the receiving (subsidized) system and free the food web, or particular consumers, from the energetic constraints of local primary production. Although cross-ecosystem subsidies between terrestrial and aquatic systems have been well recognized for benthic organisms in streams, rivers, and the littoral zones of lakes, terrestrial subsidies to pelagic consumers are more difficult to demonstrate and remain controversial. Here, we adopt a unique approach by using stable isotopes of H, C, and N to estimate terrestrial support to zooplankton in two contrasting lakes. Zooplankton (Holopedium, Daphnia, and Leptodiaptomus) are comprised of ???20-40% of organic material of terrestrial origin. These estimates are as high as, or higher than, prior measures obtained by experimentally manipulating the inorganic 13C content of these lakes to augment the small, natural contrast in 13C between terrestrial and algal photosynthesis. Our study gives credence to a growing literature, which we review here, suggesting that significant terrestrial support of pelagic crustaceans (zooplankton) is widespread.

  5. Strong evidence for terrestrial support of zooplankton in small lakes based on stable isotopes of carbon, nitrogen, and hydrogen

    PubMed Central

    Cole, Jonathan J.; Carpenter, Stephen R.; Kitchell, Jim; Pace, Michael L.; Solomon, Christopher T.; Weidel, Brian

    2011-01-01

    Cross-ecosystem subsidies to food webs can alter metabolic balances in the receiving (subsidized) system and free the food web, or particular consumers, from the energetic constraints of local primary production. Although cross-ecosystem subsidies between terrestrial and aquatic systems have been well recognized for benthic organisms in streams, rivers, and the littoral zones of lakes, terrestrial subsidies to pelagic consumers are more difficult to demonstrate and remain controversial. Here, we adopt a unique approach by using stable isotopes of H, C, and N to estimate terrestrial support to zooplankton in two contrasting lakes. Zooplankton (Holopedium, Daphnia, and Leptodiaptomus) are comprised of ≈20–40% of organic material of terrestrial origin. These estimates are as high as, or higher than, prior measures obtained by experimentally manipulating the inorganic 13C content of these lakes to augment the small, natural contrast in 13C between terrestrial and algal photosynthesis. Our study gives credence to a growing literature, which we review here, suggesting that significant terrestrial support of pelagic crustaceans (zooplankton) is widespread. PMID:21245299

  6. Tectonic contrasts between Venus and the earth

    NASA Technical Reports Server (NTRS)

    Kaula, W. M.

    1984-01-01

    The long-wave features of the gravity field of Venus differ from those of the earth's field not only in their strong positive correlation with topography, but also in their gentler spectral slope. These properties are inconsistent with generation of the gravity field by plate tectonics or by processes at great depths; they are consistent with generation by a mantle convective system supporting the broad features in topography with an effective compensation depth of about 450 km.

  7. Observation of Lyman-alpha emission in interplanetary space

    NASA Technical Reports Server (NTRS)

    Bertaux, J. L.; Blamont, J. E.

    1972-01-01

    The extraterrestrial Lyman-alpha emission was mapped by the OGO 5 satellite, when it was outside the geocorona. Three maps, obtained at different periods of the year, are presented and analyzed. The results suggest that at least half of the emission takes place in the solar system, and give strong support to the theory that in its motion toward the apex, the sun crosses neutral atomic hydrogen of interstellar origin, giving rise to an apparent interstellar wind.

  8. Induction of Type 1 Immune Responses to SIV by IFN-Gamma

    DTIC Science & Technology

    1997-06-01

    of rhesus macaques vaccinated with recombinant vaccinia viruses ( rVVs). Five animals were vaccinated with 107 pfu of vHuy/SIVgen, a Wyeth rVV...predominance of SIVAnef viruses . There is strong evidence to support the critical role of the cell-mediated arm of the immune system in the control of HIV...manufacturers, and imnmunofluorescence was measured with a dual- laser flow cytometer (FACSCAN, Becton Dickinson). -9- Induction of Type I Inmune Responses

  9. The Impacts of Humanitarian Assistance/Disaster Relief Operations on the Mental Health of Marines

    DTIC Science & Technology

    2015-12-01

    ICD International Classification of Diseases MCTFS Marine Corps Total Forces System MOS Military Occupational Specialty OEF Operation Enduring...for their unwavering support throughout this process, as well as my entire career. I have been fortunate enough to be blessed with two strong parents...thesis I am very proud of. Thank you both. Finally, I want to thank my Marines. They are why I am here. Semper Fidelis. xvi THIS PAGE INTENTIONALLY

  10. A systematic review of near real-time and point-of-care clinical decision support in anesthesia information management systems.

    PubMed

    Simpao, Allan F; Tan, Jonathan M; Lingappan, Arul M; Gálvez, Jorge A; Morgan, Sherry E; Krall, Michael A

    2017-10-01

    Anesthesia information management systems (AIMS) are sophisticated hardware and software technology solutions that can provide electronic feedback to anesthesia providers. This feedback can be tailored to provide clinical decision support (CDS) to aid clinicians with patient care processes, documentation compliance, and resource utilization. We conducted a systematic review of peer-reviewed articles on near real-time and point-of-care CDS within AIMS using the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols. Studies were identified by searches of the electronic databases Medline and EMBASE. Two reviewers screened studies based on title, abstract, and full text. Studies that were similar in intervention and desired outcome were grouped into CDS categories. Three reviewers graded the evidence within each category. The final analysis included 25 articles on CDS as implemented within AIMS. CDS categories included perioperative antibiotic prophylaxis, post-operative nausea and vomiting prophylaxis, vital sign monitors and alarms, glucose management, blood pressure management, ventilator management, clinical documentation, and resource utilization. Of these categories, the reviewers graded perioperative antibiotic prophylaxis and clinical documentation as having strong evidence per the peer reviewed literature. There is strong evidence for the inclusion of near real-time and point-of-care CDS in AIMS to enhance compliance with perioperative antibiotic prophylaxis and clinical documentation. Additional research is needed in many other areas of AIMS-based CDS.

  11. High Resolution Studies Of Lensed z ∼ 2 Galaxies: Kinematics And Metal Gradients

    NASA Astrophysics Data System (ADS)

    Leethochawalit, Nicha

    2016-09-01

    We use the OSIRIS integral field unit (IFU) spectograph to secure spatially-resolved strong emission lines of 15 gravitationally-lensed star-forming galaxies at redshift z ∼ 2. With the aid of gravitational lensing and Keck laser-assisted adaptive optics, the spatial resolution of these sub-luminous galaxies is at a few hundred parsecs. First, we demonstrate that high spatial resolution is crucial in diagnosing the kinematic properties and dynamical maturity of z ∼ 2 galaxies. We observe a significantly lower fraction of rotationally-supported systems than what has been claimed in lower spatial resolution surveys. Second, we find a much larger fraction of z ∼ 2 galaxies with weak metallicity gradients, contrary to the simple picture suggested by earlier studies that well-ordered rotation develops concurrently with established steep metal gradients in all but merging systems. Comparing our observations with the predictions of hydronamical simulations, strong feedback is likely to play a key role in flattening metal gradients in early star-forming galaxies.

  12. The evolution of sex roles in birds is related to adult sex ratio.

    PubMed

    Liker, András; Freckleton, Robert P; Székely, Tamás

    2013-01-01

    Sex-role reversal represents a formidable challenge for evolutionary biologists, since it is not clear which ecological, life-history or social factors facilitated conventional sex roles (female care and male-male competition for mates) to be reversed (male care and female-female competition). Classic theories suggested ecological or life-history predictors of role reversal, but most studies failed to support these hypotheses. Recent theory however predicts that sex-role reversal should be driven by male-biased adult sex ratio (ASR). Here we test this prediction for the first time using phylogenetic comparative analyses. Consistent with theory, both mating system and parental care are strongly related to ASR in shorebirds: conventional sex roles are exhibited by species with female-biased ASR, whereas sex-role reversal is associated with male-biased ASR. These results suggest that social environment has a strong influence on breeding systems and therefore revealing the causes of ASR variation in wild populations is essential for understanding sex role evolution.

  13. Evaluation of a performance appraisal framework for radiation therapists in planning and simulation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Becker, Jillian, E-mail: jillian.becker@health.qld.gov.au; Bridge, Pete; Brown, Elizabeth

    2015-06-15

    Constantly evolving technology and techniques within radiation therapy require practitioners to maintain a continuous approach to professional development and training. Systems of performance appraisal and adoption of regular feedback mechanisms are vital to support this development yet frequently lack structure and rely on informal peer support. A Radiation Therapy Performance Appraisal Framework (RT-PAF) for radiation therapists in planning and simulation was developed to define expectations of practice and promote a supportive and objective culture of performance and skills appraisal. Evaluation of the framework was conducted via an anonymous online survey tool. Nine peer reviewers and fourteen recipients provided feedback onmore » its effectiveness and the challenges and limitations of the approach. Findings from the evaluation were positive and suggested that both groups gained benefit from and expressed a strong interest in embedding the approach more routinely. Respondents identified common challenges related to the limited ability to implement suggested development strategies; this was strongly associated with time and rostering issues. This framework successfully defined expectations for practice and provided a fair and objective feedback process that focussed on skills development. It empowered staff to maintain their skills and reach their professional potential. Management support, particularly in regard to provision of protected time was highlighted as critical to the framework's ongoing success. The demonstrated benefits arising in terms of staff satisfaction and development highlight the importance of this commitment to the modern radiation therapy workforce.« less

  14. A recurrence network approach to analyzing forced synchronization in hydrodynamic systems

    NASA Astrophysics Data System (ADS)

    Murugesan, Meenatchidevi; Zhu, Yuanhang; Li, Larry K. B.

    2016-11-01

    Hydrodynamically self-excited systems can lock into external forcing, but their lock-in boundaries and the specific bifurcations through which they lock in can be difficult to detect. We propose using recurrence networks to analyze forced synchronization in a hydrodynamic system: a low-density jet. We find that as the jet bifurcates from periodicity (unforced) to quasiperiodicity (weak forcing) and then to lock-in (strong forcing), its recurrence network changes from a regular distribution of links between nodes (unforced) to a disordered topology (weak forcing) and then to a regular distribution again at lock-in (strong forcing). The emergence of order at lock-in can be either smooth or abrupt depending on the specific lock-in route taken. Furthermore, we find that before lock-in, the probability distribution of links in the network is a function of the characteristic scales of the system, which can be quantified with network measures and used to estimate the proximity to the lock-in boundaries. This study shows that recurrence networks can be used (i) to detect lock-in, (ii) to distinguish between different routes to lock-in, and (iii) as an early warning indicator of the proximity of a system to its lock-in boundaries. This work was supported by the Research Grants Council of Hong Kong (Project No. 16235716 and 26202815).

  15. The NASA Electric Propulsion Program

    NASA Technical Reports Server (NTRS)

    Callahan, Lisa Wood; Curran, Francis M.

    1996-01-01

    Nearly all space missions require on-board propulsion systems and these systems typically have a major impact on spacecraft mass and cost. Electric propulsion systems offer major performance advantages over conventional chemical systems for many mission functions and the NASA Office of Space Access and Technology (OSAT) supports an extensive effort to develop the technology for high-performance, on-board electric propulsion system options to enhance and enable near- and far-term US space missions. This program includes research and development efforts on electrothermal, electrostatic, and electromagnetic propulsion system technologies to cover a wide range of potential applications. To maximize expectations of technology transfer, the program emphasizes strong interaction with the user community through a variety of cooperative and contracted approaches. This paper provides an overview of the OSAT electric propulsion program with an emphasis on recent progress and future directions.

  16. Attitudes toward Abortion among Providers of Reproductive Health Care.

    PubMed

    Dodge, Laura E; Haider, Sadia; Hacker, Michele R

    2016-01-01

    Access to abortion continues to decrease in the United States. The aim of this study was to explore attitudes toward abortion among clinicians who provide reproductive health care. Clinician members of several reproductive health professional organizations completed a self-administered survey that assessed their attitudes toward abortion. A total of 278 clinicians who provided clinical reproductive health services within the United States were included. Nearly all strongly agreed that abortion should be available in cases of rape (89.6%), incest (89.2%), life endangerment (93.2%), health endangerment (91.0%), and fetal anomaly (85.9%). Although most strongly disagreed that spousal notification (81.3%) and spousal consent (86.6%) should be required for married women, fewer strongly disagreed that parental notification (57.6%) and parental consent (66.9%) should be required for minors. Respondents were generally supportive of private insurance coverage (70.1% strongly agreed) and Medicaid coverage (65.0% strongly agreed) for abortion services. Support for legal abortion and public funding of abortion were significantly associated with being female (both p ≤ .03) and having no personal religious affiliation (both p ≤ .04). Younger respondents and men were more supportive of third-party involvement and mandatory counseling (all p ≤ .02). Abortion providers were significantly more supportive of abortion access (legality of abortion, public and private funding, no third-party involvement, and no mandated counseling) than nonproviders (all p < .001). Although reproductive health care providers were generally supportive of legal abortion and funding for abortion, lower support among younger respondents may indicate future difficulties in maintaining a clinical workforce that is willing to provide abortion care. Copyright © 2016 Jacobs Institute of Women's Health. Published by Elsevier Inc. All rights reserved.

  17. High-speed duplex optical wireless communication system for indoor personal area networks.

    PubMed

    Wang, Ke; Nirmalathas, Ampalavanapillai; Lim, Christina; Skafidas, Efstratios

    2010-11-22

    In this paper a new hybrid wireless access system incorporating high bandwidth line-of-sight free space optical wireless and radio frequency localization is proposed and demonstrated. This system is capable of supporting several gigabits/second up-stream and down-stream data transmission and ideally suited for high bandwidth indoor applications such as personal area networks. A radio frequency signal is used to achieve localization of subscribers, offering limited mobility to subscribers within a practical office scenario. Even with the modest transmitted power of 5 dBm, we demonstrate satisfactory performance of bit error rates better than 10(-9) over the entire room in the presence of strong background light. Using simulations, the effectiveness of the proposed system architecture is investigated and the key performance trade-offs identified. Proof-of-concept experiments have also been carried out to validate simulation model, and initial experimental results successfully demonstrate the feasibility of the system capable of supporting 2.5 Gbps over a 1-2 m optical wireless link (limited by the length of the sliding rail used in the experiment) with a 45 degrees diffused beam in an indoor environment for the first time.

  18. Response to comments on "Productivity is a poor predictor of plant species richness"

    USGS Publications Warehouse

    Grace, James B.; Adler, Peter B.; Seabloom, Eric W.; Borer, Elizabeth T.; Hillebrand, Helmut; Hautier, Yann; Hector, Andy; Harpole, W. Stanley; O'Halloran, Lydia R.; Anderson, T. Michael; Bakker, Jonathan D.; Brown, Cynthia S.; Buckley, Yvonne M.; Collins, Scott L.; Cottingham, Kathryn L.; Crawley, Michael J.; Damschen, Ellen Ingman; Davies, Kendi F.; DeCrappeo, Nicole M.; Fay, Philip A.; Firn, Jennifer; Gruner, Daniel S.; Hagenah, Nicole; Jin, Virginia L.; Kirkman, Kevin P.; Knops, Johannes M.H.; La Pierre, Kimberly J.; Lambrinos, John G.; Melbourne, Brett A.; Mitchell, Charles E.; Moore, Joslin L.; Morgan, John W.; Orrock, John L.; Prover, Suzanne M.; Stevens, Carly J.; Wragg, Peter D.; Yang, Louie H.

    2012-01-01

    Pan et al. claim that our results actually support a strong linear positive relationship between productivity and richness, whereas Fridley et al. contend that the data support a strong humped relationship. These responses illustrate how preoccupation with bivariate patterns distracts from a deeper understanding of the multivariate mechanisms that control these important ecosystem properties.

  19. eXascale PRogramming Environment and System Software (XPRESS)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chapman, Barbara; Gabriel, Edgar

    Exascale systems, with a thousand times the compute capacity of today’s leading edge petascale computers, are expected to emerge during the next decade. Their software systems will need to facilitate the exploitation of exceptional amounts of concurrency in applications, and ensure that jobs continue to run despite the occurrence of system failures and other kinds of hard and soft errors. Adapting computations at runtime to cope with changes in the execution environment, as well as to improve power and performance characteristics, is likely to become the norm. As a result, considerable innovation is required to develop system support to meetmore » the needs of future computing platforms. The XPRESS project aims to develop and prototype a revolutionary software system for extreme-­scale computing for both exascale and strong­scaled problems. The XPRESS collaborative research project will advance the state-­of-­the-­art in high performance computing and enable exascale computing for current and future DOE mission-­critical applications and supporting systems. The goals of the XPRESS research project are to: A. enable exascale performance capability for DOE applications, both current and future, B. develop and deliver a practical computing system software X-­stack, OpenX, for future practical DOE exascale computing systems, and C. provide programming methods and environments for effective means of expressing application and system software for portable exascale system execution.« less

  20. Risk stratification in patients with advanced heart failure requiring biventricular assist device support as a bridge to cardiac transplantation.

    PubMed

    Cheng, Richard K; Deng, Mario C; Tseng, Chi-hong; Shemin, Richard J; Kubak, Bernard M; MacLellan, W Robb

    2012-08-01

    Prior studies have identified risk factors for survival in patients with end-stage heart failure (HF) requiring left ventricular assist device (LVAD) support. However, patients with biventricular HF may represent a unique cohort. We retrospectively evaluated a consecutive cohort of 113 adult, end-stage HF patients at University of California Los Angeles Medical Center who required BIVAD support between 2000 and 2009. Survival to transplant was 66.4%, with 1-year actuarial survival of 62.8%. All patients were Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) Level 1 or 2 and received Thoratec (Pleasanton, CA) paracorporeal BIVAD as a bridge to transplant. Univariate analyses showed dialysis use, ventilator use, extracorporal membrane oxygenation use, low cardiac output, preserved LV ejection fraction (restrictive physiology), normal-to-high sodium, low platelet count, low total cholesterol, low high-density and high-density lipoprotein, low albumin, and elevated aspartate aminotransferase were associated with increased risk of death. We generated a scoring system for survival to transplant. Our final model, with age, sex, dialysis, cholesterol, ventilator, and albumin, gave a C-statistic of 0.870. A simplified system preserved a C-statistic of 0.844. Patients were divided into high-risk or highest-risk groups (median respective survival, 367 and 17 days), with strong discrimination between groups for death. We have generated a scoring system that offers high prognostic ability for patients requiring BIVAD support and hope that it may assist in clinical decision making. Further studies are needed to prospectively validate our scoring system. Copyright © 2012 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.

  1. Advances and Computational Tools towards Predictable Design in Biological Engineering

    PubMed Central

    2014-01-01

    The design process of complex systems in all the fields of engineering requires a set of quantitatively characterized components and a method to predict the output of systems composed by such elements. This strategy relies on the modularity of the used components or the prediction of their context-dependent behaviour, when parts functioning depends on the specific context. Mathematical models usually support the whole process by guiding the selection of parts and by predicting the output of interconnected systems. Such bottom-up design process cannot be trivially adopted for biological systems engineering, since parts function is hard to predict when components are reused in different contexts. This issue and the intrinsic complexity of living systems limit the capability of synthetic biologists to predict the quantitative behaviour of biological systems. The high potential of synthetic biology strongly depends on the capability of mastering this issue. This review discusses the predictability issues of basic biological parts (promoters, ribosome binding sites, coding sequences, transcriptional terminators, and plasmids) when used to engineer simple and complex gene expression systems in Escherichia coli. A comparison between bottom-up and trial-and-error approaches is performed for all the discussed elements and mathematical models supporting the prediction of parts behaviour are illustrated. PMID:25161694

  2. Identifying strongly correlated elements of a moderately correlated wavefunction in URu2Si2 with resonant inelastic X-ray scattering

    NASA Astrophysics Data System (ADS)

    Wray, L. Andrew; He, Haowei; Miao, Lin; Denlinger, Jonathan; Chuang, Yi-De; Yang, Wanli; Butch, Nicholas; Maple, Brian; Gray, Alexander; Dürr, Herman

    The RIXS technique is best known for significant breakthroughs in the investigation of strongly correlated materials such as cuprates. However, the rapid advancement of RIXS spectrographs has made it increasingly attractive to apply the technique to a broad range of quantum materials outside of this comfort zone. This talk will review lessons learned from our recent measurements on material systems that feature a balance of correlated and itinerant physics, focusing on the hidden order compound URu2Si2, and touching on VO2 and Prussian blue analogue battery electrodes. RIXS spectra are found to reveal essential features defining low energy degrees of freedom in these moderately correlated wavefunctions. In the case of URu2Si2, we show that a principal energy gap defining strong correlations is fragile, and can be melted via modest chemical doping. Work at NYU was supported by the MRSEC Program of the National Science Foundation under Award Number DMR-1420073.

  3. Control of Electron Flow Direction in Photoexcited Cycloplatinated Complex Containing Conjugated Polymer-Single Walled Carbon Nanotube Hybrids.

    PubMed

    Xiong, Wenjuan; Du, Lili; Lo, Kin Cheung; Shi, Haiting; Takaya, Tomohisa; Iwata, Koichi; Chan, Wai Kin; Phillips, David Lee

    2018-06-25

    Conjugated polymers incorporated with cycloplatinated complexes (P1-Pt and P2-Pt) were used as dispersants for single walled carbon nanotubes (SWCNTs). Significant changes in the UV-vis absorption spectra were observed after the formation of the polymer/SWCNT hybrids. Molecular dynamics (MD) simulations revealed the presence of a strong interaction between the cycloplatinated complex moieties and the SWCNT surface. The photoinduced electron transfer processes in these hybrids were strongly dependent on the type of the comonomer unit. Upon photoexcitation, the excited P1-Pt donates electrons to the SWCNT, while P2-Pt accepts electrons from the photoexcited SWCNT. These observations were supported by results from Raman and femtosecond time-resolved transient absorption spectroscopy experiments. The strong electronic interaction between the Pt complexes and the SWCNT gives rise to a new hybrid system that has a controllable photo-induced electron transfer flow, which are important in regulating the charge transport processes SWCNT-based optoelectronic devices.

  4. Ebola virus disease outbreak; the role of field epidemiology training programme in the fight against the epidemic, Liberia, 2014.

    PubMed

    Lubogo, Mutaawe; Donewell, Bangure; Godbless, Lucas; Shabani, Sasita; Maeda, Justin; Temba, Herilinda; Malibiche, Theophil C; Berhanu, Naod

    2015-01-01

    The African Field Epidemiology Network (AFENET) is a public health network established in 2005 as a non-profit networking alliance of Field Epidemiology and Laboratory Training Programs (FELTPs) and Field Epidemiology Training Programs (FETPs) in Africa. AFENET is dedicated to supporting Ministries of Health in Africa build strong, effective and sustainable programs and capacity to improve public health systems by partnering with global public health experts. The Network's goal is to strengthen field epidemiology and public health laboratory capacity to contribute effectively to addressing epidemics and other major public health problems in Africa. The goal for the establishment of FETP and FELTP was and still is to produce highly competent multi-disciplinary public health professionals who would assume influential posts in the public health structures and tackle emerging and re-emerging communicable and non-communicable diseases. AFENET currently networks 12 FELTPs and FETPs in sub-Saharan Africa with operations in 20 countries. During the Ebola Virus Disease (EVD) outbreak in West Africa, African Union Support for the Ebola Outbreak in West Africa (ASEOWA) supported FETP graduates from Uganda, Zimbabwe, Ethiopia and Tanzania for the investigation and control of the EVD outbreak in Liberia. The graduates were posted in different counties in Liberia where they lead teams of other experts conduct EVD outbreak investigations, Infection Control and Prevention trainings among health workers and communities, Strengthening integrated disease surveillance, developing Standard Operating Procedures for infection control and case notification in the Liberian setting as well as building capacity of local surveillance officers' conduct outbreak investigation and contact tracing. The team was also responsible for EVD data management at the different Counties in Liberia. The FETP graduates have been instrumental in the earlier successes registered in various counties in Liberia in the control of the Ebola virus disease. Such efforts should be sustained by supporting local authorities develop strong health systems that are able to respond to epidemic of such magnitude in the near future.

  5. Ebola virus disease outbreak; the role of field epidemiology training programme in the fight against the epidemic, Liberia, 2014

    PubMed Central

    Lubogo, Mutaawe; Donewell, Bangure; Godbless, Lucas; Shabani, Sasita; Maeda, Justin; Temba, Herilinda; Malibiche, Theophil C; Berhanu, Naod

    2015-01-01

    The African Field Epidemiology Network (AFENET) is a public health network established in 2005 as a non-profit networking alliance of Field Epidemiology and Laboratory Training Programs (FELTPs) and Field Epidemiology Training Programs (FETPs) in Africa. AFENET is dedicated to supporting Ministries of Health in Africa build strong, effective and sustainable programs and capacity to improve public health systems by partnering with global public health experts. The Network's goal is to strengthen field epidemiology and public health laboratory capacity to contribute effectively to addressing epidemics and other major public health problems in Africa. The goal for the establishment of FETP and FELTP was and still is to produce highly competent multi-disciplinary public health professionals who would assume influential posts in the public health structures and tackle emerging and re-emerging communicable and non-communicable diseases. AFENET currently networks 12 FELTPs and FETPs in sub-Saharan Africa with operations in 20 countries. During the Ebola Virus Disease (EVD) outbreak in West Africa, African Union Support for the Ebola Outbreak in West Africa (ASEOWA) supported FETP graduates from Uganda, Zimbabwe, Ethiopia and Tanzania for the investigation and control of the EVD outbreak in Liberia. The graduates were posted in different counties in Liberia where they lead teams of other experts conduct EVD outbreak investigations, Infection Control and Prevention trainings among health workers and communities, Strengthening integrated disease surveillance, developing Standard Operating Procedures for infection control and case notification in the Liberian setting as well as building capacity of local surveillance officers’ conduct outbreak investigation and contact tracing. The team was also responsible for EVD data management at the different Counties in Liberia. The FETP graduates have been instrumental in the earlier successes registered in various counties in Liberia in the control of the Ebola virus disease. Such efforts should be sustained by supporting local authorities develop strong health systems that are able to respond to epidemic of such magnitude in the near future. PMID:26779298

  6. The Role of Emotion in Global Warming Policy Support and Opposition

    PubMed Central

    Smith, Nicholas; Leiserowitz, Anthony

    2014-01-01

    Prior research has found that affect and affective imagery strongly influence public support for global warming. This article extends this literature by exploring the separate influence of discrete emotions. Utilizing a nationally representative survey in the United States, this study found that discrete emotions were stronger predictors of global warming policy support than cultural worldviews, negative affect, image associations, or sociodemographic variables. In particular, worry, interest, and hope were strongly associated with increased policy support. The results contribute to experiential theories of risk information processing and suggest that discrete emotions play a significant role in public support for climate change policy. Implications for climate change communication are also discussed. PMID:24219420

  7. The role of emotion in global warming policy support and opposition.

    PubMed

    Smith, Nicholas; Leiserowitz, Anthony

    2014-05-01

    Prior research has found that affect and affective imagery strongly influence public support for global warming. This article extends this literature by exploring the separate influence of discrete emotions. Utilizing a nationally representative survey in the United States, this study found that discrete emotions were stronger predictors of global warming policy support than cultural worldviews, negative affect, image associations, or sociodemographic variables. In particular, worry, interest, and hope were strongly associated with increased policy support. The results contribute to experiential theories of risk information processing and suggest that discrete emotions play a significant role in public support for climate change policy. Implications for climate change communication are also discussed. © 2013 Society for Risk Analysis.

  8. The Vagaries Of Public Support For Government Actions In Case Of A Pandemic

    PubMed Central

    Hilyard, Karen M.; Freimuth, Vicki S.; Musa, Donald; Kumar, Supriya; Quinn, Sandra Crouse

    2011-01-01

    Government health measures in a pandemic are effective only with strong support and compliance from the public. A survey of 1,583 US adults early in the 2009 H1N1 (swine influenza) pandemic shows surprisingly mixed support for possible government efforts to control the spread of the disease, with strong support for more extreme measures such as closing borders and weak support for more basic, and potentially more effective, policies such as encouraging sick people to stay home from work. The results highlight challenges that public health officials and policy makers must address in formulating strategies to respond to a pandemic before a more severe outbreak occurs. PMID:21134932

  9. Tunable resonant and non-resonant interactions between a phase qubit and LC resonator

    NASA Astrophysics Data System (ADS)

    Allman, Michael Shane; Whittaker, Jed D.; Castellanos-Beltran, Manuel; Cicak, Katarina; da Silva, Fabio; Defeo, Michael; Lecocq, Florent; Sirois, Adam; Teufel, John; Aumentado, Jose; Simmonds, Raymond W.

    2014-03-01

    We use a flux-biased radio frequency superconducting quantum interference device (rf SQUID) with an embedded flux-biased direct current (dc) SQUID to generate strong resonant and non-resonant tunable interactions between a phase qubit and a lumped-element resonator. The rf-SQUID creates a tunable magnetic susceptibility between the qubit and resonator providing resonant coupling rates from zero to near the ultra-strong coupling regime. By modulating the magnetic susceptibility, non-resonant parametric coupling achieves rates > 100 MHz . Nonlinearity of the magnetic susceptibility also leads to parametric coupling at subharmonics of the qubit-resonator detuning. Controllable coupling is generically important for constructing coupled-mode systems ubiquitous in physics, useful for both, quantum information architectures and quantum simulators. This work supported by NIST and NSA grant EAO140639.

  10. Advanced Practice Nursing Committee on Process Improvement in Trauma: An Innovative Application of the Strong Model.

    PubMed

    West, Sarah Katherine

    2016-01-01

    This article aims to summarize the successes and future implications for a nurse practitioner-driven committee on process improvement in trauma. The trauma nurse practitioner is uniquely positioned to recognize the need for clinical process improvement and enact change within the clinical setting. Application of the Strong Model of Advanced Practice proves to actively engage the trauma nurse practitioner in process improvement initiatives. Through enhancing nurse practitioner professional engagement, the committee aims to improve health care delivery to the traumatically injured patient. A retrospective review of the committee's first year reveals trauma nurse practitioner success in the domains of direct comprehensive care, support of systems, education, and leadership. The need for increased trauma nurse practitioner involvement has been identified for the domains of research and publication.

  11. Evidence of an Improper Displacive Phase Transition in Cd2 Re2 O7 via Time-Resolved Coherent Phonon Spectroscopy

    NASA Astrophysics Data System (ADS)

    Harter, J. W.; Kennes, D. M.; Chu, H.; de la Torre, A.; Zhao, Z. Y.; Yan, J.-Q.; Mandrus, D. G.; Millis, A. J.; Hsieh, D.

    2018-01-01

    We have used a combination of ultrafast coherent phonon spectroscopy, ultrafast thermometry, and time-dependent Landau theory to study the inversion symmetry breaking phase transition at Tc=200 K in the strongly spin-orbit coupled correlated metal Cd2 Re2 O7 . We establish that the structural distortion at Tc is a secondary effect through the absence of any softening of its associated phonon mode, which supports a purely electronically driven mechanism. However, the phonon lifetime exhibits an anomalously strong temperature dependence that decreases linearly to zero near Tc. We show that this behavior naturally explains the spurious appearance of phonon softening in previous Raman spectroscopy experiments and should be a prevalent feature of correlated electron systems with linearly coupled order parameters.

  12. Decisional Information System for Safety (D.I.S.S.) Dedicated to the Human Space Exploration Mission

    NASA Astrophysics Data System (ADS)

    Grès, Stéphane; Guyonnet, Jean-François

    2006-06-01

    At the heart of the issue of reliable and dependable systems and networks, this paper presents the conception of a Decisional Information System for Security (D.I.S.S.) dedicated to the Human Space Exploration Mission. The objective is to conceive a decisional information system for human long duration space flight (> 1000 days) which is realised in entire autonomy in the solar system. This article describes the importance of the epistemological and ontological context for designing an open, self-learning and reliable system able for self-adapt in dangerous and unforeseen situations. We present in link with our research, the limits of the empirical analytical paradigm and several paths of research lead by the nascent paradigm of enaction. The strong presumption is that the centralised models of security could not be sufficient today to respond and challenge the security of a technical system, which will support human exploration missions.

  13. Model Scaling of Hydrokinetic Ocean Renewable Energy Systems

    NASA Astrophysics Data System (ADS)

    von Ellenrieder, Karl; Valentine, William

    2013-11-01

    Numerical simulations are performed to validate a non-dimensional dynamic scaling procedure that can be applied to subsurface and deeply moored systems, such as hydrokinetic ocean renewable energy devices. The prototype systems are moored in water 400 m deep and include: subsurface spherical buoys moored in a shear current and excited by waves; an ocean current turbine excited by waves; and a deeply submerged spherical buoy in a shear current excited by strong current fluctuations. The corresponding model systems, which are scaled based on relative water depths of 10 m and 40 m, are also studied. For each case examined, the response of the model system closely matches the scaled response of the corresponding full-sized prototype system. The results suggest that laboratory-scale testing of complete ocean current renewable energy systems moored in a current is possible. This work was supported by the U.S. Southeast National Marine Renewable Energy Center (SNMREC).

  14. The effect of beam pre-bunching on the excitation of terahertz plasmons in a parallel plane guiding system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sharma, Suresh C.; Malik, Pratibha

    2015-04-15

    The excitation of terahertz (THz) plasmons by a pre-bunched relativistic electron beam propagating in a parallel plane semiconducting guiding system is studied. It is found that the n-InSb semiconductor strongly supports the confined surface plasmons in the terahertz frequency range. The growth rate and efficiency of the THz surface plasmons increase linearly with modulation index and show the largest value as modulation index approaches unity. Moreover, the growth rate of the instability scales as one-third power of the beam density and inverse one-third power of the THz radiation frequency.

  15. The opportunities for and challenges of common integrated electronics

    NASA Astrophysics Data System (ADS)

    Nelson, J. R.; Retterer, Bernard L.; Cloud, Harley A.

    1994-02-01

    This document summarizes a portion of IDA's work concerning common integrated electronics and the potential cost savings of using common electronic hardware and software. It addresses trends in avionics costs and recent experiences in applying common electronic standards to weapon programs as a way to reduce costs. The following essential elements of a program to acquire common integrated electronics are explored: (1) integrated system architecture; (2) advanced technology programs; (3) open system standards; (4) standard common modules; and (5) associated management and policies. The principal recommendation is that OSD support and coordinate such a-program by taking a strong leadership role and setting standards policy.

  16. Research on Modularized Design and Allocation of Infectious Disease Prevention and Control Equipment in China.

    PubMed

    Zhao, Xin; Wang, Yun-Dou; Zhang, Xiao-Feng; Gao, Shu-Tian; Guo, Li-Jun; Sun, Li-Na

    2017-06-01

    For the prevention and control of newly emergent or sudden infectious diseases, we built an on-site, modularized prevention and control system and tested the equipment by using the clustering analysis method. On the basis of this system, we propose a modular equipment allocation method and 4 applications of this method for different types of infectious disease prevention and control. This will help to improve the efficiency and productivity of anti-epidemic emergency forces and will provide strong technical support for implementing more universal and serialized equipment in China. (Disaster Med Public Health Preparedness. 2017;11:375-382).

  17. Computed tomography image using sub-terahertz waves generated from a high-T{sub c} superconducting intrinsic Josephson junction oscillator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kashiwagi, T., E-mail: kashiwagi@ims.tsukuba.ac.jp; Minami, H.; Kadowaki, K.

    2014-02-24

    A computed tomography (CT) imaging system using monochromatic sub-terahertz coherent electromagnetic waves generated from a device constructed from the intrinsic Josephson junctions in a single crystalline mesa structure of the high-T{sub c} superconductor Bi{sub 2}Sr{sub 2}CaCu{sub 2}O{sub 8+δ} was developed and tested on three samples: Standing metallic rods supported by styrofoam, a dried plant (heart pea) containing seeds, and a plastic doll inside an egg shell. The images obtained strongly suggest that this CT imaging system may be useful for a variety of practical applications.

  18. Using sparsity information for iterative phase retrieval in x-ray propagation imaging.

    PubMed

    Pein, A; Loock, S; Plonka, G; Salditt, T

    2016-04-18

    For iterative phase retrieval algorithms in near field x-ray propagation imaging experiments with a single distance measurement, it is indispensable to have a strong constraint based on a priori information about the specimen; for example, information about the specimen's support. Recently, Loock and Plonka proposed to use the a priori information that the exit wave is sparsely represented in a certain directional representation system, a so-called shearlet system. In this work, we extend this approach to complex-valued signals by applying the new shearlet constraint to amplitude and phase separately. Further, we demonstrate its applicability to experimental data.

  19. Low-Energy Theory of Disordered Graphene

    NASA Astrophysics Data System (ADS)

    Altland, Alexander

    2006-12-01

    At low values of external doping, graphene displays a wealth of unconventional transport properties. Perhaps most strikingly, it supports a robust “metallic” regime, with universal conductance of the order of the conductance quantum. We here apply a combination of mean-field and bosonization methods to explore the large scale transport properties of the system. We find that, irrespective of the doping level, disordered graphene is subject to the common mechanisms of Anderson localization. However, at low doping a number of renormalization mechanisms conspire to protect the conductivity of the system, to an extend that strong localization may not be seen even at temperatures much smaller than those underlying present experimental work.

  20. Study on Network Error Analysis and Locating based on Integrated Information Decision System

    NASA Astrophysics Data System (ADS)

    Yang, F.; Dong, Z. H.

    2017-10-01

    Integrated information decision system (IIDS) integrates multiple sub-system developed by many facilities, including almost hundred kinds of software, which provides with various services, such as email, short messages, drawing and sharing. Because the under-layer protocols are different, user standards are not unified, many errors are occurred during the stages of setup, configuration, and operation, which seriously affect the usage. Because the errors are various, which may be happened in different operation phases, stages, TCP/IP communication protocol layers, sub-system software, it is necessary to design a network error analysis and locating tool for IIDS to solve the above problems. This paper studies on network error analysis and locating based on IIDS, which provides strong theory and technology supports for the running and communicating of IIDS.

  1. Lightweight Trauma Module - LTM

    NASA Technical Reports Server (NTRS)

    Hatfield, Thomas

    2008-01-01

    Current patient movement items (PMI) supporting the military's Critical Care Air Transport Team (CCATT) mission as well as the Crew Health Care System for space (CHeCS) have significant limitations: size, weight, battery duration, and dated clinical technology. The LTM is a small, 20 lb., system integrating diagnostic and therapeutic clinical capabilities along with onboard data management, communication services and automated care algorithms to meet new Aeromedical Evacuation requirements. The Lightweight Trauma Module is an Impact Instrumentation, Inc. project with strong Industry, DoD, NASA, and Academia partnerships aimed at developing the next generation of smart and rugged critical care tools for hazardous environments ranging from the battlefield to space exploration. The LTM is a combination ventilator/critical care monitor/therapeutic system with integrated automatic control systems. Additional capabilities are provided with small external modules.

  2. Family impact of assistive technology scale: development of a measurement scale for parents of children with complex communication needs.

    PubMed

    Delarosa, Elizabeth; Horner, Stephanie; Eisenberg, Casey; Ball, Laura; Renzoni, Anne Marie; Ryan, Stephen E

    2012-09-01

    Young people use augmentative and alternative communication (AAC) systems to meet their everyday communication needs. However, the successful integration of an AAC system into a child's life requires strong commitment and continuous support from parents and other family members. This article describes the development and evaluation of the Family Impact of Assistive Technology Scale for AAC Systems - a parent-report questionnaire intended to detect the impact of AAC systems on the lives of children with complex communication needs and their families. The study involved 179 parents and clinical experts to test the content and face validities of the questionnaire, demonstrate its internal reliability and stability over time, and estimate its convergent construct validity when compared to a standardized measure of family impact.

  3. The Role of a Provider-Sponsored Health Plan in Achieving Scale and Integration.

    PubMed

    Johnson, Steven P

    2016-01-01

    In pursuit of two primary strategies-to become an integrated delivery network (IDN) on the local level and to achieve additional overall organizational scale to sustain operations-Health First, based in Rockledge, Florida, relies on the success of its provider-sponsored health plan (PSHP) as a critical asset. For Health First, the PSHP serves as an agent for holding and administering financial risk for the health of populations. In addition, we are learning that our PSHP is a critical asset in support of integrating the components of our care delivery system to manage that financial risk effectively, efficiently, and in a manner that creates a unified experience for the customer.Health First is challenged by continuing pressure on reimbursement, as well as by a substantial regulatory burden, as we work to optimize the environments and tools of care and population health management. Even with strong margins and a healthy balance sheet, we simply do not have the resources needed to bring an IDN robustly to life. However, we have discovered that our PSHP can be the vehicle that carries us to additional scale. Many health systems do not own or otherwise have access to a PSHP to hold and manage financial risk. Health First sought and found a not-for-profit health system with complementary goals and a strong brand to partner with, and we now provide private-label health plan products for that system using its strong name while operating the insurance functions under our license and with our capabilities.

  4. RADIO TRANSIENTS FROM ACCRETION-INDUCED COLLAPSE OF WHITE DWARFS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moriya, Takashi J., E-mail: takashi.moriya@nao.ac.jp

    2016-10-20

    We investigate observational properties of accretion-induced collapse (AIC) of white dwarfs (WDs) in radio frequencies. If AIC is triggered by accretion from a companion star, a dense circumstellar medium can be formed around the progenitor system. Then, the ejecta from AIC collide with the dense circumstellar medium, creating a strong shock. The strong shock can produce synchrotron emission that can be observed in radio frequencies. Even if AIC occurs as a result of WD mergers, we argue that AIC may cause fast radio bursts (FRBs) if a certain condition is satisfied. If AIC forms neutron stars (NSs) that are somore » massive that rotation is required to support themselves (i.e., supramassive NSs), the supramassive NSs may immediately lose their rotational energy by the r-mode instability and collapse to black holes. If the collapsing supramassive NSs are strongly magnetized, they may emit FRBs, as previously proposed. The AIC radio transients from single-degenerate systems may be detected in future radio transient surveys like the Very Large Array Sky Survey or the Square Kilometer Array transient survey. Because AIC has been proposed as a source of gravitational waves (GWs), GWs from AIC may be accompanied by radio-bright transients that can be used to confirm the AIC origin of observed GWs.« less

  5. Platinum nanoparticles on gallium nitride surfaces: effect of semiconductor doping on nanoparticle reactivity.

    PubMed

    Schäfer, Susanne; Wyrzgol, Sonja A; Caterino, Roberta; Jentys, Andreas; Schoell, Sebastian J; Hävecker, Michael; Knop-Gericke, Axel; Lercher, Johannes A; Sharp, Ian D; Stutzmann, Martin

    2012-08-01

    Platinum nanoparticles supported on n- and p-type gallium nitride (GaN) are investigated as novel hybrid systems for the electronic control of catalytic activity via electronic interactions with the semiconductor support. In situ oxidation and reduction were studied with high pressure photoemission spectroscopy. The experiments revealed that the underlying wide-band-gap semiconductor has a large influence on the chemical composition and oxygen affinity of supported nanoparticles under X-ray irradiation. For as-deposited Pt cuboctahedra supported on n-type GaN, a higher fraction of oxidized surface atoms was observed compared to cuboctahedral particles supported on p-type GaN. Under an oxygen atmosphere, immediate oxidation was recorded for nanoparticles on n-type GaN, whereas little oxidation was observed for nanoparticles on p-type GaN. Together, these results indicate that changes in the Pt chemical state under X-ray irradiation depend on the type of GaN doping. The strong interaction between the nanoparticles and the support is consistent with charge transfer of X-ray photogenerated free carriers at the semiconductor-nanoparticle interface and suggests that GaN is a promising wide-band-gap support material for photocatalysis and electronic control of catalysis.

  6. 13 CFR 301.8 - Application evaluation criteria.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... private sector investment resulting from an Investment. (b) Has strong organizational leadership. An Investment will have strong leadership, relevant Project management experience and a significant commitment... leadership and support by local elected officials; and (3) Strong cooperation among the business sector...

  7. 13 CFR 301.8 - Application evaluation criteria.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... private sector investment resulting from an Investment. (b) Has strong organizational leadership. An Investment will have strong leadership, relevant Project management experience and a significant commitment... leadership and support by local elected officials; and (3) Strong cooperation among the business sector...

  8. 13 CFR 301.8 - Application evaluation criteria.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... private sector investment resulting from an Investment. (b) Has strong organizational leadership. An Investment will have strong leadership, relevant Project management experience and a significant commitment... leadership and support by local elected officials; and (3) Strong cooperation among the business sector...

  9. Gold nanoparticles with different capping systems: an electronic and structural XAS analysis.

    PubMed

    López-Cartes, C; Rojas, T C; Litrán, R; Martínez-Martínez, D; de la Fuente, J M; Penadés, S; Fernández, A

    2005-05-12

    Gold nanoparticles (NPs) have been prepared with three different capping systems: a tetralkylammonium salt, an alkanethiol, and a thiol-derivatized neoglycoconjugate. Also gold NPs supported on a porous TiO(2) substrate have been investigated. X-ray absorption spectroscopy (XAS) has been used to determine the electronic behavior of the different capped/supported systems regarding the electron/hole density of d states. Surface and size effects, as well as the role of the microstructure, have been also studied through an exhaustive analysis of the EXAFS (extended X-ray absorption fine structure) data. Very small gold NPs functionalized with thiol-derivatized molecules show an increase in d-hole density at the gold site due to Au-S charge transfer. This effect is overcoming size effects (which lead to a slightly increase of the d-electron density) for high S:Au atomic ratios and core-shell microstructures where an atomically abrupt Au-S interface likely does not exist. It has been also shown that thiol functionalization of very small gold NPs is introducing a strong distortion as compared to fcc order. To the contrary, electron transfer from reduced support oxides to gold NPs can produce a higher increase in d-electron density at the gold site, as compared to naked gold clusters.

  10. Discovery of a drug targeting microenvironmental support for lymphoma cells by screening using patient-derived xenograft cells

    PubMed Central

    Sugimoto, Keiki; Hayakawa, Fumihiko; Shimada, Satoko; Morishita, Takanobu; Shimada, Kazuyuki; Katakai, Tomoya; Tomita, Akihiro; Kiyoi, Hitoshi; Naoe, Tomoki

    2015-01-01

    Cell lines have been used for drug discovery as useful models of cancers; however, they do not recapitulate cancers faithfully, especially in the points of rapid growth rate and microenvironment independency. Consequently, the majority of conventional anti-cancer drugs are less sensitive to slow growing cells and do not target microenvironmental support, although most primary cancer cells grow slower than cell lines and depend on microenvironmental support. Here, we developed a novel high throughput drug screening system using patient-derived xenograft (PDX) cells of lymphoma that maintained primary cancer cell phenotype more than cell lines. The library containing 2613 known pharmacologically active substance and off-patent drugs were screened by this system. We could find many compounds showing higher cytotoxicity than conventional anti-tumor drugs. Especially, pyruvinium pamoate showed the highest activity and its strong anti-tumor effect was confirmed also in vivo. We extensively investigated its mechanism of action and found that it inhibited glutathione supply from stromal cells to lymphoma cells, implying the importance of the stromal protection from oxidative stress for lymphoma cell survival and a new therapeutic strategy for lymphoma. Our system introduces a primary cancer cell phenotype into cell-based phenotype screening and sheds new light on anti-cancer drug development. PMID:26278963

  11. Intermittency inhibited by transport: An exactly solvable model

    NASA Astrophysics Data System (ADS)

    Zanette, Damián H.

    1994-04-01

    Transport is incorporated in a discrete-time stochastic model of a system undergoing autocatalytic reactions of the type A-->2A and A-->0, whose population field is known to exhibit spatiotemporal intermittency. The temporal evolution is exactly solved, and it is shown that if the transport process is strong enough, intermittency is inhibited. This inhibition is nonuniform, in the sense that, as transport is strengthened, low-order population moments are affected before the high-order ones. Numerical simulations are presented to support the analytical results.

  12. System dynamics and simulation of LSS

    NASA Technical Reports Server (NTRS)

    Ryan, R. F.

    1978-01-01

    Large Space Structures have many unique problems arising from mission objectives and the resulting configuration. Inherent in these configurations is a strong coupling among several of the designing disciplines. In particular, the coupling between structural dynamics and control is a key design consideration. The solution to these interactive problems requires efficient and accurate analysis, simulation and test techniques, and properly planned and conducted design trade studies. The discussion presented deals with these subjects and concludes with a brief look at some NASA capabilities which can support these technology studies.

  13. Combining total energy and energy industrial center concepts to increase utilization efficiency of geothermal energy

    NASA Technical Reports Server (NTRS)

    Bayliss, B. P.

    1974-01-01

    Integrating energy production and energy consumption to produce a total energy system within an energy industrial center which would result in more power production from a given energy source and less pollution of the environment is discussed. Strong governmental support would be required for the crash drilling program necessary to implement these concepts. Cooperation among the federal agencies, power producers, and private industry would be essential in avoiding redundant and fruitless projects, and in exploiting most efficiently our geothermal resources.

  14. Plans for the development of cryogenic engines for space exploration

    NASA Technical Reports Server (NTRS)

    Stone, James R.; Shaw, Loretta M.; Aukerman, Carl A.

    1991-01-01

    The NASA Lewis Research Center (LeRC) is conducting a broad range of basic research and focused technology development activities in both aeronautical and space propulsion. By virtue of the successful conduct of these programs, LeRC is strongly qualified to lead Advanced Development and subsequent development programs on cryogenic space propulsion systems on support of the Space Exploration Initiative. A review is provided of technology status, including recent progress in the ongoing activities, and a top level description of the proposed program.

  15. Analytical Support for the Joint Chiefs of Staff: The WSEG Experience, 1948-1976

    DTIC Science & Technology

    1979-07-01

    high-level officials who participated ŕ’"Directive, Weapons Systems Evaluations Group," En ( Losure to SecDef Memorandum for the Joint Chiefs of Staff...and the field was becoming estab- lished as an identifiable discipline in its own right. 1 2 By and large, the World War II mob ization of science and...3trategic nuclear weapons, e,, en at the expense of other capabilities. They were strongly opposed by defenders of combined operations and balanced force

  16. Observation of migrating transverse Anderson localizations of light in nonlocal media.

    PubMed

    Leonetti, Marco; Karbasi, Salman; Mafi, Arash; Conti, Claudio

    2014-05-16

    We report the experimental observation of the interaction and attraction of many localized modes in a two-dimensional system realized by a disordered optical fiber supporting transverse Anderson localization. We show that a nonlocal optically nonlinear response of thermal origin alters the localization length by an amount determined by the optical power and also induces an action at a distance between the localized modes and their spatial migration. Evidence of a collective and strongly interacting regime is given.

  17. Fermion mass without symmetry breaking

    DOE PAGES

    Catterall, Simon

    2016-01-20

    We examine a model of reduced staggered fermions in three dimensions interacting through an SO (4) invariant four fermion interaction. The model is similar to that considered in a recent paper by Ayyer and Chandrasekharan. We present theoretical arguments and numerical evidence which support the idea that the system develops a mass gap for sufficiently strong four fermi coupling without producing a symmetry breaking fermion bilinear condensate. As a result, massless and massive phases appear to be separated by a continuous phase transition.

  18. Solitons in a one-dimensional Wigner crystal

    DOE PAGES

    Pustilnik, M.; Matveev, K. A.

    2015-04-16

    In one-dimensional quantum systems with strong long-range repulsion particles arrange in a quasi-periodic chain, the Wigner crystal. Here, we demonstrate that besides the familiar phonons, such one-dimensional Wigner crystal supports an additional mode of elementary excitations, which can be identified with solitons in the classical limit. Furthermore, we compute the corresponding excitation spectrum and argue that the solitons have a parametrically small decay rate at low energies. Finally, we discuss implications of our results for the behavior of the dynamic structure factor.

  19. Apollo 1 Astronaut Roger Chaffee

    NASA Image and Video Library

    1965-11-17

    Astronaut Roger Chaffee on the Reduced Gravity Walking Simulator located at the Lunar Landing Facility. The purpose of this simulator was to study the subject while walking, jumping or running. Researchers conducted studies of various factors such as fatigue limit, energy expenditure, and speed of locomotion. A.W. Vigil, described the simulator as follows: "When the astronauts land on the moon they will be in an unfamiliar environment involving, particularly, a gravitational field only one-sixth as strong as on earth. A novel method of simulating lunar gravity has been developed and is supported by a puppet-type suspension system at the end of a long pendulum. A floor is provided at the proper angle so that one-sixth of the subject's weight is supported by the floor with the remainder being supported by the suspension system. This simulator allows almost complete freedom in vertical translation and pitch and is considered to be a very realistic simulation of the lunar walking problem. For this problem this simulator suffers only slightly from the restrictions in lateral movement it puts on the test subject. This is not considered a strong disadvantage for ordinary walking problems since most of the motions do, in fact, occur in the vertical plane. However, this simulation technique would be severely restrictive if applied to the study of the extra-vehicular locomotion problem, for example, because in this situation complete six degrees of freedom are rather necessary. This technique, in effect, automatically introduces a two-axis attitude stabilization system into the problem. The technique could, however, be used in preliminary studies of extra-vehicular locomotion where, for example, it might be assumed that one axis of the attitude control system on the astronaut maneuvering unit may have failed." -- Published in James R. Hansen, Spaceflight Revolution: NASA Langley Research Center From Sputnik to Apollo, NASA SP-4308, p. 377; A.W. Vigil, "Discussion of Existing and Planned Simulators for Space Research," Paper presented at Conference on the Role of Simulation in Space Technology," Blacksburg, VA, August 17-21, 1964.

  20. Reduced Gravity Walking Simulator

    NASA Image and Video Library

    1963-10-24

    Reduced Gravity Walking Simulator located in the hangar at Langley Research Center. The initial version of this simulator was located inside the hanger. Later a larger version would be located at the Lunar Landing Facility. The purpose of this simulator was to study the subject while walking, jumping or running. Researchers conducted studies of various factors such as fatigue limit, energy expenditure, and speed of locomotion. A.W. Vigil wrote in his paper Discussion of Existing and Planned Simulators for Space Research, When the astronauts land on the moon they will be in an unfamiliar environment involving, particularly, a gravitational field only one-sixth as strong as on earth. A novel method of simulating lunar gravity has been developed and is supported by a puppet-type suspension system at the end of a long pendulum. A floor is provided at the proper angle so that one-sixth of the subject' s weight is supported by the floor with the remainder being supported by the suspension system. This simulator allows almost complete freedom in vertical translation and pitch and is considered to be a very realistic simulation of the lunar walking problem. For this problem this simulator suffers only slightly from the restrictions in lateral movement it puts on the test subject. This is not considered a strong disadvantage for ordinary walking problems since most of the motions do, in fact, occur in the vertical plane. However, this simulation technique would be severely restrictive if applied to the study of the extra-vehicular locomotion problem, for example, because in this situation complete six degrees of freedom are rather necessary. This technique, in effect, automatically introduces a two-axis attitude stabilization system into the problem. The technique could, however, be used in preliminary studies of extra-vehicular locomotion where, for example, it might be assumed that one axis of the attitude control system on the astronaut maneuvering unit may have failed. -- Published in James R. Hansen, Spaceflight Revolution: NASA Langley Research Center From Sputnik to Apollo, NASA SP-4308, p. 377 A.W. Vigil, Discussion of Existing and Planned Simulators for Space Research, Paper presented at Conference on the Role of Simulation in Space Technology, Blacksburg, VA, August 17-21, 1964.

  1. Special "space" suit for the Reduced Gravity Walking Simulator

    NASA Image and Video Library

    1965-05-05

    Special "space" suit for the Reduced Gravity Walking Simulator located at the Lunar Landing Facility. The purpose of this simulator was to study the subject while walking, jumping or running. Researchers conducted studies of various factors such as fatigue limit, energy expenditure, and speed of locomotion. A.W. Vigil described the purpose of the simulator in his paper "Discussion of Existing and Planned Simulators for Space Research," "When the astronauts land on the moon they will be in an unfamiliar environment involving, particularly, a gravitational field only one-sixth as strong as on earth. A novel method of simulating lunar gravity has been developed and is supported by a puppet-type suspension system at the end of a long pendulum. A floor is provided at the proper angle so that one-sixth of the subject's weight is supported by the floor with the remainder being supported by the suspension system. This simulator allows almost complete freedom in vertical translation and pitch and is considered to be a very realistic simulation of the lunar walking problem. For this problem this simulator suffers only slightly from the restrictions in lateral movement it puts on the test subject. This is not considered a strong disadvantage for ordinary walking problems since most of the motions do, in fact, occur in the vertical plane. However, this simulation technique would be severely restrictive if applied to the study of the extra-vehicular locomotion problem, for example, because in this situation complete six degrees of freedom are rather necessary. This technique, in effect, automatically introduces a two-axis attitude stabilization system into the problem. The technique could, however, be used in preliminary studies of extra-vehicular locomotion where, for example, it might be assumed that one axis of the attitude control system on the astronaut maneuvering unit may have failed." -- Published in James R. Hansen, Spaceflight Revolution: NASA Langley Research Center From Sputnik to Apollo, (Washington: NASA, 1995), p. 377; A.W. Vigil, "Discussion of Existing and Planned Simulators for Space Research," Paper presented at Conference on the Role of Simulation in Space Technology," Blacksburg, VA, August 17-21, 1964.

  2. Astronaut Walt Cunningham on the Reduced Gravity Walking Simulator

    NASA Image and Video Library

    1965-06-24

    Astronaut Walt Cunningham on the Reduced Gravity Walking Simulator located at the Lunar Landing Facility. The purpose of this simulator was to study the subject while walking, jumping or running. Researchers conducted studies of various factors such as fatigue limit, energy expenditure, and speed of locomotion. A.W. Vigil described the purpose of the simulator in his paper "Discussion of Existing and Planned Simulators for Space Research," "When the astronauts land on the moon they will be in an unfamiliar environment involving, particularly, a gravitational field only one-sixth as strong as on earth. A novel method of simulating lunar gravity has been developed and is supported by a puppet-type suspension system at the end of a long pendulum. A floor is provided at the proper angle so that one-sixth of the subject's weight is supported by the floor with the remainder being supported by the suspension system. This simulator allows almost complete freedom in vertical translation and pitch and is considered to be a very realistic simulation of the lunar walking problem. For this problem this simulator suffers only slightly from the restrictions in lateral movement it puts on the test subject. This is not considered a strong disadvantage for ordinary walking problems since most of the motions do, in fact, occur in the vertical plane. However, this simulation technique would be severely restrictive if applied to the study of the extra-vehicular locomotion problem, for example, because in this situation complete six degrees of freedom are rather necessary. This technique, in effect, automatically introduces a two-axis attitude stabilization system into the problem. The technique could, however, be used in preliminary studies of extra-vehicular locomotion where, for example, it might be assumed that one axis of the attitude control system on the astronaut maneuvering unit may have failed." -- Published in James R. Hansen, Spaceflight Revolution: NASA Langley Research Center From Sputnik to Apollo, (Washington: NASA, 1995), p. 377; A.W. Vigil, "Discussion of Existing and Planned Simulators for Space Research," Paper presented at Conference on the Role of Simulation in Space Technology," Blacksburg, VA, August 17-21, 1964.

  3. Reduced Gravity Walking Simulator

    NASA Image and Video Library

    2012-09-07

    Test subject wearing the pressurized "space" suit for the Reduced Gravity Walking Simulator located at the Lunar Landing Facility. The purpose of this simulator was to study the subject while walking, jumping or running. Researchers conducted studies of various factors such as fatigue limit, energy expenditure, and speed of locomotion. A.W. Vigil described the purpose of the simulator in his paper "Discussion of Existing and Planned Simulators for Space Research," "When the astronauts land on the moon they will be in an unfamiliar environment involving, particularly, a gravitational field only one-sixth as strong as on earth. A novel method of simulating lunar gravity has been developed and is supported by a puppet-type suspension system at the end of a long pendulum. A floor is provided at the proper angle so that one-sixth of the subject's weight is supported by the floor with the remainder being supported by the suspension system. This simulator allows almost complete freedom in vertical translation and pitch and is considered to be a very realistic simulation of the lunar walking problem. For this problem this simulator suffers only slightly from the restrictions in lateral movement it puts on the test subject. This is not considered a strong disadvantage for ordinary walking problems since most of the motions do, in fact, occur in the vertical plane. However, this simulation technique would be severely restrictive if applied to the study of the extra-vehicular locomotion problem, for example, because in this situation complete six degrees of freedom are rather necessary. This technique, in effect, automatically introduces a two-axis attitude stabilization system into the problem. The technique could, however, be used in preliminary studies of extra-vehicular locomotion where, for example, it might be assumed that one axis of the attitude control system on the astronaut maneuvering unit may have failed." -- Published in James R. Hansen, Spaceflight Revolution: NASA Langley Research Center From Sputnik to Apollo, (Washington: NASA, 1995), p. 377; A.W. Vigil, "Discussion of Existing and Planned Simulators for Space Research," Paper presented at Conference on the Role of Simulation in Space Technology," Blacksburg, VA, August 17-21, 1964.

  4. Structural and Acidic Properties of Niobia-Silica and Niobia-Alumina Aerogels

    DTIC Science & Technology

    1991-05-06

    some weak Bronsted acidity. The silica aerogel supported niobia samples also had strong Lewis acidity as well as strong iv Bronsted acidity which was...NS25w or the silica aerogel supported niobia because of the formation of a distorted octahedral niobia-rigid silica interface. Isomerization of 1...67 2.1.2 Silica Aerogel .......................................................... 70 2.1.3 Alumina

  5. Medical-School Partnership in Guiding Return to School Following Mild Traumatic Brain Injury in Youth

    PubMed Central

    Gioia, Gerard A.

    2015-01-01

    Mild traumatic brain injury (mTBI) is recognized as a prevalent and significant risk concern for youth. Appropriate school return is particularly challenging. The medical and school systems must be prepared partners to support the school return of the student with mTBI. Medical providers must be trained in assessment and management skills with a focused understanding of school demands. Schools must develop policies and procedures to prepare staff to support a gradual return process with the necessary academic accommodations. Ongoing communication between the family, student, school, and medical provider is essential to supporting recovery. A systematic gradual return to school process is proposed including levels of recommended activity and criteria for advancement. Targets for intervention are described with associated strategies for supporting recovery. A ten element PACE model for activity-exertion management is introduced to manage symptom exacerbation. A strong medical-school partnership will maximize outcomes for students with mTBI. PMID:25535055

  6. What keeps you strong? A systematic review identifying how primary health-care and aged-care services can support the well-being of older Indigenous peoples.

    PubMed

    Davy, Carol; Kite, Elaine; Aitken, Graham; Dodd, Garth; Rigney, Janice; Hayes, Jenny; Van Emden, Jan

    2016-06-01

    The objective of this systematic review was to identify primary health-care or aged-care strategies that have or could support the well-being of older Indigenous peoples. A search was undertaken of primary databases including Medical Literature Analysis and Retrieval System Online and Cumulative Index to Nursing and Allied Health Literature. Papers which reported on the perspectives of older Indigenous peoples, community members and provider participants were included. Findings were pooled using a meta-aggregative approach. Three high-level synthesised findings - maintaining Indigenous identity, promoting independence and delivering culturally safe care - were believed to be important for supporting the well-being of older Indigenous peoples. As physical independence often diminishes with age, having the support of culturally safe primary health-care and aged-care services that understand the importance of maintaining an Indigenous identity and promoting independence will be crucial for the well-being of older Indigenous peoples. © 2016 AJA Inc.

  7. The Visual System of Zebrafish and its Use to Model Human Ocular Diseases

    PubMed Central

    Gestri, Gaia; Link, Brian A; Neuhauss, Stephan CF

    2011-01-01

    Free swimming zebrafish larvae depend mainly on their sense of vision to evade predation and to catch prey. Hence there is strong selective pressure on the fast maturation of visual function and indeed the visual system already supports a number of visually-driven behaviors in the newly hatched larvae. The ability to exploit the genetic and embryonic accessibility of the zebrafish in combination with a behavioral assessment of visual system function has made the zebrafish a popular model to study vision and its diseases. Here, we review the anatomy, physiology and development of the zebrafish eye as the basis to relate the contributions of the zebrafish to our understanding of human ocular diseases. PMID:21595048

  8. Using policy to increase prescribing of smoking cessation medications in the VA healthcare system.

    PubMed

    Smith, Mark W; Chen, Shuo; Siroka, Andrew M; Hamlett-Berry, Kim

    2010-12-01

    Since 2002 the US Veterans Affairs (VA) healthcare system has initiated national policies and programmes to reduce smoking among its patients and to increase evidence-based treatment for smoking. To document changes in dispensing rates of cessation-related medications in VA from 2004 to 2008. Retrospective analysis of VA administrative data. Prescription fills for nicotine replacement therapy (NRT), and for bupropion among NRT users, each grew more than 60% in four years. The increase stemmed primarily from treating more people rather than from filling more prescriptions per person. The results provide strong support for the efficacy of these policies and illustrate how healthcare systems can successfully employ multiple strategies to increase evidence-based smoking-cessation treatment.

  9. A systematic review including meta-analysis of work environment and burnout symptoms.

    PubMed

    Aronsson, Gunnar; Theorell, Töres; Grape, Tom; Hammarström, Anne; Hogstedt, Christer; Marteinsdottir, Ina; Skoog, Ingmar; Träskman-Bendz, Lil; Hall, Charlotte

    2017-03-16

    Practitioners and decision makers in the medical and insurance systems need knowledge on the relationship between work exposures and burnout. Many burnout studies - original as well as reviews - restricted their analyses to emotional exhaustion or did not report results on cynicism, personal accomplishment or global burnout. To meet this need we carried out this review and meta-analyses with the aim to provide systematically graded evidence for associations between working conditions and near-future development of burnout symptoms. A wide range of work exposure factors was screened. Inclusion criteria were: 1) Study performed in Europe, North America, Australia and New Zealand 1990-2013. 2) Prospective or comparable case control design. 3) Assessments of exposure (work) and outcome at baseline and at least once again during follow up 1-5 years later. Twenty-five articles met the predefined relevance and quality criteria. The GRADE-system with its 4-grade evidence scale was used. Most of the 25 studies focused emotional exhaustion, fewer cynicism and still fewer personal accomplishment. Moderately strong evidence (grade 3) was concluded for the association between job control and reduced emotional exhaustion and between low workplace support and increased emotional exhaustion. Limited evidence (grade 2) was found for the associations between workplace justice, demands, high work load, low reward, low supervisor support, low co-worker support, job insecurity and change in emotional exhaustion. Cynicism was associated with most of these work factors. Reduced personal accomplishment was only associated with low reward. There were few prospective studies with sufficient quality on adverse chemical, biological and physical factors and burnout. While high levels of job support and workplace justice were protective for emotional exhaustion, high demands, low job control, high work load, low reward and job insecurity increased the risk for developing exhaustion. Our approach with a wide range of work exposure factors analysed in relation to the separate dimensions of burnout expanded the knowledge of associations, evidence as well as research needs. The potential of organizational interventions is illustrated by the findings that burnout symptoms are strongly influenced by structural factors such as job demands, support and the possibility to exert control.

  10. Triple loop heat exchanger for an absorption refrigeration system

    DOEpatents

    Reimann, Robert C.

    1984-01-01

    A triple loop heat exchanger for an absorption refrigeration system is disclosed. The triple loop heat exchanger comprises portions of a strong solution line for conducting relatively hot, strong solution from a generator to a solution heat exchanger of the absorption refrigeration system, conduit means for conducting relatively cool, weak solution from the solution heat exchanger to the generator, and a bypass system for conducting strong solution from the generator around the strong solution line and around the solution heat exchanger to an absorber of the refrigeration system when strong solution builds up in the generator to an undesirable level. The strong solution line and the conduit means are in heat exchange relationship with each other in the triple loop heat exchanger so that, during normal operation of the refrigeration system, heat is exchanged between the relatively hot, strong solution flowing through the strong solution line and the relatively cool, weak solution flowing through the conduit means. Also, the strong solution line and the bypass system are in heat exchange relationship in the triple loop heat exchanger so that if the normal flow path of relatively hot, strong solution flowing from the generator to an absorber is blocked, then this relatively, hot strong solution which will then be flowing through the bypass system in the triple loop heat exchanger, is brought into heat exchange relationship with any strong solution which may have solidified in the strong solution line in the triple loop heat exchanger to thereby aid in desolidifying any such solidified strong solution.

  11. Impact of care management processes and integration of care on blood pressure control in diabetes.

    PubMed

    Wong, Ken; Boulanger, Luke; Smalarz, Amy; Wu, Ning; Fraser, Kimberly; Wogen, Jenifer

    2013-02-27

    Fragmentation within health care systems may negatively impact the quality of chronic disease patient care. We sought to evaluate the relationship between care management processes (CMP), integration of services, and blood pressure (BP) control among diabetic patients. Retrospective chart reviews were performed for a random sample of adult diabetic hypertensive patients (n = 2,162) from 28 physician organizations in the United States (US). A modified version of the Physician Practice Connection Readiness Survey (PPC-RS) was completed by the chief medical officer at each site. The PPC-RS measured health system organization, delivery system redesign, decision support, clinical information systems, and self-management support, and an integration scale measured structure, functions, and financial risk. Correlations between PPC and integration scores and BP outcomes were assessed using Spearman correlation coefficients. Approximately 39.9% of diabetic patients had controlled BP. Mean total PPC score across sites was 55, with highest mean scores for health system organization (81), followed by design support (60), clinical information systems (57), self-management support (39), and delivery system redesign (39). Mean integration score was 46 (SD 27, range 4-93), and means of subscores were 64 for structure, 33 for financial risk, and 42 for function. Clinical information systems subscore was correlated with uncontrolled BP (r = -0.38, p < 0.05), while association with total PPC score was strong but not significant at p < 0.05 (r = -0.32). Total integration score and the structure subscore were significantly correlated with BP control (r = 0.38, p < 0.05, and r = 0.49, p < 0.01). This study suggests that CMP and service integration may be associated with better outcomes in diabetes, though results were mixed and limited by a small number of participating sites. Primary care implementation of integrated electronic medical records may have a beneficial effect on patient outcomes for diabetes and other chronic diseases.

  12. Digital rights language support for evolving digital cinema requirements

    NASA Astrophysics Data System (ADS)

    Orri, Xavier; Mas, Joan-Maria; Macq, Benoit M. M.

    2003-06-01

    Digital cinema can be defined as the digital electronic distribution and display of theatrical film content or live material to the theatre. However, this simple definition does not reflect the complex mesh of balanced business relationships between the different parties involved in the worldwide cinematic distribution. Its transition from an analogue to a digital business will happen progressively, starting with only content being digitally distributed and going until an all-digital business. From these facts derive strong requirements on digital rights management (DRM) systems for digital cinema and therefore on the digital rights language supporting it. This paper explores the requirements imposed by the cinematic distribution model and by its progressive transition to digital, and the impact these have on digital rights languages. We analyze the support provided by different digital rights languages, identifying weaknesses and exploring solutions in fulfilling the requirements of the digital cinema distribution model.

  13. Episodic Reasoning for Vision-Based Human Action Recognition

    PubMed Central

    Martinez-del-Rincon, Jesus

    2014-01-01

    Smart Spaces, Ambient Intelligence, and Ambient Assisted Living are environmental paradigms that strongly depend on their capability to recognize human actions. While most solutions rest on sensor value interpretations and video analysis applications, few have realized the importance of incorporating common-sense capabilities to support the recognition process. Unfortunately, human action recognition cannot be successfully accomplished by only analyzing body postures. On the contrary, this task should be supported by profound knowledge of human agency nature and its tight connection to the reasons and motivations that explain it. The combination of this knowledge and the knowledge about how the world works is essential for recognizing and understanding human actions without committing common-senseless mistakes. This work demonstrates the impact that episodic reasoning has in improving the accuracy of a computer vision system for human action recognition. This work also presents formalization, implementation, and evaluation details of the knowledge model that supports the episodic reasoning. PMID:24959602

  14. Design and Implementation of Surrounding Transaction Plotting and Management System Based on Google Map API

    NASA Astrophysics Data System (ADS)

    Cao, Y. B.; Hua, Y. X.; Zhao, J. X.; Guo, S. M.

    2013-11-01

    With China's rapid economic development and comprehensive national strength growing, Border work has become a long-term and important task in China's diplomatic work. How to implement rapid plotting, real-time sharing and mapping surrounding affairs has taken great significance for government policy makers and diplomatic staff. However, at present the already exists Boundary information system are mainly have problems of Geospatial data update is heavily workload, plotting tools are in a state of serious lack of, Geographic events are difficult to share, this phenomenon has seriously hampered the smooth development of the border task. The development and progress of Geographic information system technology especially the development of Web GIS offers the possibility to solve the above problems, this paper adopts four layers of B/S architecture, with the support of Google maps service, uses the free API which is offered by Google maps and its features of openness, ease of use, sharing characteristics, highresolution images to design and implement the surrounding transaction plotting and management system based on the web development technology of ASP.NET, C#, Ajax. The system can provide decision support for government policy makers as well as diplomatic staff's real-time plotting and sharing of surrounding information. The practice has proved that the system has good usability and strong real-time.

  15. Selective interactions among Rh, ABO, and sex ratio of newborns.

    PubMed

    Valenzuela, C Y; Walton, R

    1985-01-01

    The hypothesis that the Rh and ABO blood systems behave like the HLA system in relation to mother-conception tolerance-rejection mechanisms was tested in 25,501 mother-infant pairs. According to this hypothesis, heterozygotes carrying a paternal gene that is not present in their mothers should be better tolerated than homozygotes. Significantly more BO infants born to AO mothers. AO infants born to BO mothers, Rh(+) heterozygotes born to Rh(-) mothers, and less significantly AO infants born to OO mothers confirm the hypothesis. Fewer homozygotes occurred in Rh(-) infants born to Rh(+) mothers and in O infants born to non-O mothers. Deviations from the Hardy-Weinberg equilibrium found in the ABO system were modified by the Rh and sex of the infant. These data strongly support the hypothesis that at least two feto-maternal systems influence the destiny of pregnancies: the classical known incompatibility system which operates late in pregnancy and a new one which is based on the induction of maternal tolerance early in pregnancy: maternal tolerance seems to be better elicited by heterozygous eggs or embryos carrying a gene not present in the mother. The data also support the hypothesis that the sex ratio is influenced by feto-maternal tolerance-rejection mechanisms associated with the ABO and Rh systems.

  16. Correlated Electrons in Reduced Dimensions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bonesteel, Nicholas E

    2015-01-31

    This report summarizes the work accomplished under the support of US DOE grant # DE-FG02-97ER45639, "Correlated Electrons in Reduced Dimensions." The underlying hypothesis of the research supported by this grant has been that studying the unique behavior of correlated electrons in reduced dimensions can lead to new ways of understanding how matter can order and how it can potentially be used. The systems under study have included i) fractional quantum Hall matter, which is realized when electrons are confined to two-dimensions and placed in a strong magnetic field at low temperature, ii) one-dimensional chains of spins and exotic quasiparticle excitationsmore » of topologically ordered matter, and iii) electrons confined in effectively ``zero-dimensional" semiconductor quantum dots.« less

  17. From the Office of the National Coordinator: the strategy for advancing the exchange of health information.

    PubMed

    Williams, Claudia; Mostashari, Farzad; Mertz, Kory; Hogin, Emily; Atwal, Parmeeth

    2012-03-01

    Electronic health information exchange addresses a critical need in the US health care system to have information follow patients to support patient care. Today little information is shared electronically, leaving doctors without the information they need to provide the best care. With payment reforms providing a strong business driver, the demand for health information exchange is poised to grow. The Office of the National Coordinator for Health Information Technology, Department of Health and Human Services, has led the process of establishing the essential building blocks that will support health information exchange. Over the coming year, this office will develop additional policies and standards that will make information exchange easier and cheaper and facilitate its use on a broader scale.

  18. Classification of processes involved in sharing individual participant data from clinical trials.

    PubMed

    Ohmann, Christian; Canham, Steve; Banzi, Rita; Kuchinke, Wolfgang; Battaglia, Serena

    2018-01-01

    Background: In recent years, a cultural change in the handling of data from research has resulted in the strong promotion of a culture of openness and increased sharing of data. In the area of clinical trials, sharing of individual participant data involves a complex set of processes and the interaction of many actors and actions. Individual services/tools to support data sharing are available, but what is missing is a detailed, structured and comprehensive list of processes/subprocesses involved and tools/services needed. Methods : Principles and recommendations from a published data sharing consensus document are analysed in detail by a small expert group. Processes/subprocesses involved in data sharing are identified and linked to actors and possible services/tools. Definitions are adapted from the business process model and notation (BPMN) and applied in the analysis. Results: A detailed and comprehensive list of individual processes/subprocesses involved in data sharing, structured according to 9 main processes, is provided. Possible tools/services to support these processes/subprocesses are identified and grouped according to major type of support. Conclusions: The list of individual processes/subprocesses and tools/services identified is a first step towards development of a generic framework or architecture for sharing of data from clinical trials. Such a framework is strongly needed to give an overview of how various actors, research processes and services could form an interoperable system for data sharing.

  19. Classification of processes involved in sharing individual participant data from clinical trials

    PubMed Central

    Ohmann, Christian; Canham, Steve; Banzi, Rita; Kuchinke, Wolfgang; Battaglia, Serena

    2018-01-01

    Background: In recent years, a cultural change in the handling of data from research has resulted in the strong promotion of a culture of openness and increased sharing of data. In the area of clinical trials, sharing of individual participant data involves a complex set of processes and the interaction of many actors and actions. Individual services/tools to support data sharing are available, but what is missing is a detailed, structured and comprehensive list of processes/subprocesses involved and tools/services needed. Methods: Principles and recommendations from a published data sharing consensus document are analysed in detail by a small expert group. Processes/subprocesses involved in data sharing are identified and linked to actors and possible services/tools. Definitions are adapted from the business process model and notation (BPMN) and applied in the analysis. Results: A detailed and comprehensive list of individual processes/subprocesses involved in data sharing, structured according to 9 main processes, is provided. Possible tools/services to support these processes/subprocesses are identified and grouped according to major type of support. Conclusions: The list of individual processes/subprocesses and tools/services identified is a first step towards development of a generic framework or architecture for sharing of data from clinical trials. Such a framework is strongly needed to give an overview of how various actors, research processes and services could form an interoperable system for data sharing. PMID:29623192

  20. Demonstration of Effects on Tropical Cyclone Forecasts with a High Resolution Global Model from Variation in Cumulus Convection Parameterization

    NASA Technical Reports Server (NTRS)

    Miller, Timothy L.; Robertson, Franklin R.; Cohen, Charles; Mackaro, Jessica

    2009-01-01

    The Goddard Earth Observing System Model, Version 5 (GEOS-5) is a system of models that have been developed at Goddard Space Flight Center to support NASA's earth science research in data analysis, observing system modeling and design, climate and weather prediction, and basic research. The work presented used GEOS-5 with 0.25o horizontal resolution and 72 vertical levels (up to 0.01 hP) resolving both the troposphere and stratosphere, with closer packing of the levels close to the surface. The model includes explicit (grid-scale) moist physics, as well as convective parameterization schemes. Results will be presented that will demonstrate strong dependence in the results of modeling of a strong hurricane on the type of convective parameterization scheme used. The previous standard (default) option in the model was the Relaxed Arakawa-Schubert (RAS) scheme, which uses a quasi-equilibrium closure. In the cases shown, this scheme does not permit the efficient development of a strong storm in comparison with observations. When this scheme is replaced by a modified version of the Kain-Fritsch scheme, which was originally developed for use on grids with intervals of order 25 km such as the present one, the storm is able to develop to a much greater extent, closer to that of reality. Details of the two cases will be shown in order to elucidate the differences in the two modeled storms.

  1. Many-Objective Robust Decision Making: Managing Water in a Deeply Uncertain World of Change (Invited)

    NASA Astrophysics Data System (ADS)

    Reed, P. M.

    2013-12-01

    Water resources planning and management has always required the consideration of uncertainties and the associated system vulnerabilities that they may cause. Despite the long legacy of these issues, our decision support frameworks that have dominated the literature over the past 50 years have struggled with the strongly multiobjective and deeply uncertain nature of water resources systems. The term deep uncertainty (or Knightian uncertainty) refers to factors in planning that strongly shape system risks that maybe unknown and even if known there is a strong lack of consensus on their likelihoods over decadal planning horizons (population growth, financial stability, valuation of resources, ecosystem requirements, evolving water institutions, regulations, etc). In this presentation, I will propose and demonstrate the many-objective robust decision making (MORDM) framework for water resources management under deep uncertainty. The MORDM framework will be demonstrated using an urban water portfolio management test case. In the test case, a city in the Lower Rio Grande Valley managing population and drought pressures must cost effectively maintain the reliability of its water supply by blending permanent rights to reservoir inflows with alternative strategies for purchasing water within the region's water market. The case study illustrates the significant potential pitfalls in the classic Cost-Reliability conception of the problem. Moreover, the proposed MORDM framework exploits recent advances in multiobjective search, visualization, and sensitivity analysis to better expose these pitfalls en route to identifying highly robust water planning alternatives.

  2. Public Preferences for the Use of Taxation and Labelling Policy Measures to Combat Obesity in Young Children in Australia

    PubMed Central

    Comans, Tracy; Moretto, Nicole; Byrnes, Joshua

    2017-01-01

    Objective: Childhood obesity is a serious concern for developed and developing countries. This study aimed to assess the level of support in Australia for regulation and to assess whether systematic differences occur between individuals who support increased regulation and individuals who oppose it. Methods: An online survey (n = 563) was used to assess parental/caregiver preferences for taxation policy options and nutrition labelling designed to address the incidence of childhood obesity. Participants were parents or caregivers of young children (3 to 7 years) who were actively enrolled in an existing birth cohort study in South-East Queensland, Australia. Results: The majority of the parents (over 80%) strongly agreed or agreed with labelling food and drink with traffic light or teaspoon labelling. Support for taxation was more variable with around one third strongly supporting and a further 40% of participants equivocal about using taxation; however, a quarter strongly rejected this policy. Cluster analysis did not detect any socio-demographic differences between those who strongly supported taxation and those who did not. Conclusions: Better food labelling would be welcomed by parents to enhance food choices for their children. Taxation for health reasons would not be opposed by most parents. Implications for Public Health: Governments should consider taxation of unhealthy drinks and improved labelling to encourage healthy food purchasing. PMID:28335575

  3. Public Preferences for the Use of Taxation and Labelling Policy Measures to Combat Obesity in Young Children in Australia.

    PubMed

    Comans, Tracy; Moretto, Nicole; Byrnes, Joshua

    2017-03-21

    Objective : Childhood obesity is a serious concern for developed and developing countries. This study aimed to assess the level of support in Australia for regulation and to assess whether systematic differences occur between individuals who support increased regulation and individuals who oppose it. Methods : An online survey ( n = 563) was used to assess parental/caregiver preferences for taxation policy options and nutrition labelling designed to address the incidence of childhood obesity. Participants were parents or caregivers of young children (3 to 7 years) who were actively enrolled in an existing birth cohort study in South-East Queensland, Australia. Results : The majority of the parents (over 80%) strongly agreed or agreed with labelling food and drink with traffic light or teaspoon labelling. Support for taxation was more variable with around one third strongly supporting and a further 40% of participants equivocal about using taxation; however, a quarter strongly rejected this policy. Cluster analysis did not detect any socio-demographic differences between those who strongly supported taxation and those who did not. Conclusions : Better food labelling would be welcomed by parents to enhance food choices for their children. Taxation for health reasons would not be opposed by most parents. Implications for Public Health: Governments should consider taxation of unhealthy drinks and improved labelling to encourage healthy food purchasing.

  4. Ecosystem Functions Connecting Contributions from Ecosystem Services to Human Wellbeing in a Mangrove System in Northern Taiwan.

    PubMed

    Hsieh, Hwey-Lian; Lin, Hsing-Juh; Shih, Shang-Shu; Chen, Chang-Po

    2015-06-09

    The present study examined a mangrove ecosystem in northern Taiwan to determine how the various components of ecosystem function, ecosystem services and human wellbeing are connected. The overall contributions of mangrove services to specific components of human wellbeing were also assessed. A network was developed and evaluated by an expert panel consisting of hydrologists, ecologists, and experts in the field of culture, landscape or architecture. The results showed that supporting habitats was the most important function to human wellbeing, while water quality, habitable climate, air quality, recreational opportunities, and knowledge systems were services that were strongly linked to human welfare. Security of continuous supply of services appeared to be the key to a comfortable life. From a bottom-up and top-down perspective, knowledge systems (a service) were most supported by ecosystem functions, while the security of continuous supply of services (wellbeing) had affected the most services. In addition, the overall benefits of mangrove services to human prosperity concentrated on mental health, security of continuous supply of services, and physical health.

  5. Ecosystem Functions Connecting Contributions from Ecosystem Services to Human Wellbeing in a Mangrove System in Northern Taiwan

    PubMed Central

    Hsieh, Hwey-Lian; Lin, Hsing-Juh; Shih, Shang-Shu; Chen, Chang-Po

    2015-01-01

    The present study examined a mangrove ecosystem in northern Taiwan to determine how the various components of ecosystem function, ecosystem services and human wellbeing are connected. The overall contributions of mangrove services to specific components of human wellbeing were also assessed. A network was developed and evaluated by an expert panel consisting of hydrologists, ecologists, and experts in the field of culture, landscape or architecture. The results showed that supporting habitats was the most important function to human wellbeing, while water quality, habitable climate, air quality, recreational opportunities, and knowledge systems were services that were strongly linked to human welfare. Security of continuous supply of services appeared to be the key to a comfortable life. From a bottom-up and top-down perspective, knowledge systems (a service) were most supported by ecosystem functions, while the security of continuous supply of services (wellbeing) had affected the most services. In addition, the overall benefits of mangrove services to human prosperity concentrated on mental health, security of continuous supply of services, and physical health. PMID:26067989

  6. Primary health care in Canada: systems in motion.

    PubMed

    Hutchison, Brian; Levesque, Jean-Frederic; Strumpf, Erin; Coyle, Natalie

    2011-06-01

    During the 1980s and 1990s, innovations in the organization, funding, and delivery of primary health care in Canada were at the periphery of the system rather than at its core. In the early 2000s, a new policy environment emerged. This policy analysis examines primary health care reform efforts in Canada during the last decade, drawing on descriptive information from published and gray literature and from a series of semistructured interviews with informed observers of primary health care in Canada. Primary health care in Canada has entered a period of potentially transformative change. Key initiatives include support for interprofessional primary health care teams, group practices and networks, patient enrollment with a primary care provider, financial incentives and blended-payment schemes, development of primary health care governance mechanisms, expansion of the primary health care provider pool, implementation of electronic medical records, and quality improvement training and support. Canada's experience suggests that primary health care transformation can be achieved voluntarily in a pluralistic system of private health care delivery, given strong government and professional leadership working in concert. © 2011 Milbank Memorial Fund. Published by Wiley Periodicals Inc.

  7. Mesoscale Variability in SUCCESS Data

    NASA Technical Reports Server (NTRS)

    Eckermann, Stephen D.; Stewart, Richard W. (Technical Monitor)

    1998-01-01

    Analysis of meteorological, chemical and microphysical data from the airborne SUCCESS (SUbsonic aircraft Contrail and Cloud Effects Special Study) mission is reported. Careful analysis of the complex DC-8 flight pattern of May 2, 1996 reveals 19 linear flight segments within six main geographical areas, which we have analyzed. Significant mountain wave activity is revealed in the data from the MMS (Meteorology Measurement System) and MTP (Microwave Temperature Profiler) instruments on the DC-8, which resembles previous observations of mountain wave structures near Boulder, Colorado. Strong mountain-wave-induced upwelling downwind of the Rockies is noted. Turbulence is also noted in regions of the mountain wave consistent with overturning near the tropopause. Zonal winds recorded on the ER-2 are shown to be consistent with mountain wave breaking at or near critical levels in the stratosphere, consistent with the strong turbulence reported by the pilot during the ER-2 flight. These observations have been supported with spectral analyses and modeling studies. 'Postcasts' of mountain wave activity on May 2, 1996 using the Naval Research Laboratory Mountain Wave Forecast Model predicts both strong mountain wave activity near the tropopause and strong mountain-wave-induced turbulence in the stratosphere.

  8. A randomized clinical trial of a postdeployment parenting intervention for service members and their families with very young children.

    PubMed

    DeVoe, Ellen R; Paris, Ruth; Emmert-Aronson, Ben; Ross, Abigail; Acker, Michelle

    2017-08-01

    Parenting through the deployment cycle presents unique stressors for military families. To date, few evidence-based and military-specific parenting programs are available to support parenting through cycles of deployment separation and reintegration, especially for National Guard/Reserve members. The purpose of this research was to test the efficacy of a parenting program developed specifically to support military families during reintegration. Within 1 year of returning from deployment to Afghanistan or Iraq, 115 service members with very young children were randomly assigned to receive either the Strong Families Strong Forces Parenting Program at baseline or after a 12-week waiting period. Using a home-based modality, service members, at-home parents, and their young child were assessed at baseline, 3 months posttreatment/wait period, and 6 months from baseline. Service member parents in Strong Families evidenced greater reductions in parenting stress and mental health distress relative to those in the waitlist comparison group. Service members with more posttraumatic stress symptoms reported higher levels of perceived parental efficacy in the intervention group than service members in the comparison group. Intervention also resulted in enhanced parental reflective capacity, including increased curiosity and interest in the young child among those in the intervention group relative to comparison. Service member parents and their spouses demonstrated high interest in participating in a postdeployment parenting program targeting families with very young children. Findings point to the feasibility, appeal, and efficacy of Strong Families in this initial trial and suggest promise for implementation in broader military and community service systems. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  9. Collaborative mental health services in primary care systems in Latin America: contextualized evaluation needs and opportunities.

    PubMed

    Sapag, Jaime C; Rush, Brian; Ferris, Lorraine E

    2016-02-01

    This study examined Latin American evaluation needs regarding the development of a collaborative mental health care (CMHC) evaluation framework as seen by local key health-care leaders and professionals. Potential implementation challenges and opportunities were also identified. This multisite research study used an embedded mixed methods approach in three public health networks in Mexico, Nicaragua and Chile. Local stakeholders participated: decision-makers in key informant interviews, front-line clinicians in focus groups and other stakeholders through a survey. The analysis was conducted within site and then across sites. A total of 22 semi-structured interviews, three focus groups and 27 questionnaires (52% response rate) were conducted. Participants recognized a strong need to evaluate different areas of CMHC in Latin America, including access, types and quality of services, human resources and outcomes related to mental disorders, including addiction. A priority was to evaluate collaboration within the health system, including the referral system. Issues of feasibility, including the weaknesses of information systems, were also identified. Local stakeholders strongly supported the development of a comprehensive evaluation framework for CMHC in Latin America and cited several dimensions and contextual factors critical for inclusion. Implementation must allow flexibility and adaptation to the local context. © 2015 John Wiley & Sons Ltd.

  10. A Study of the Carbon Cycle Using NASA Observations and the GEOS Model

    NASA Technical Reports Server (NTRS)

    Pawson, Steven; Gelaro, Ron; Ott, Lesley; Putman, Bill; Chatterjee, Abhishek; Koster, Randy; Lee, Eunjee; Oda, Tom; Weir, Brad; Zeng, Fanwei

    2018-01-01

    The Goddard Earth Observing System (GEOS) model has been developed in the Global Modeling and Assimilation Office (GMAO) at NASA's Goddard Space Flight Center. From its roots in chemical transport and as a General Circulation Model, the GEOS model has been extended to an Earth System Model based on a modular construction using the Earth System Modeling Framework (ESMF), combining elements developed in house in the GMAO with others that are imported through collaborative research. It is used extensively for research and for product generation, both as a free-running model and as the core of the GMAO's data assimilation system. In recent years, the GMAO's modeling and assimilation efforts have been strongly supported by Piers Sellers, building on both his earlier legacy as an observationally oriented model developer and his post-astronaut career as a dynamic leader into new territory. Piers' long-standing interest in the carbon cycle and the combination of models with observations motivates this presentation, which will focus on the representation of the carbon cycle in the GEOS Earth System Model. Examples will include: (i) the progression from specified land-atmosphere surface fluxes to computations with an interactive model component (Catchment-CN), along with constraints on vegetation distributions using satellite observations; (ii) the use of high-resolution satellite observations to constrain human-generated inputs to the atmosphere; (iii) studies of the consistency of the observed atmospheric carbon dioxide concentrations with those in the model simulations. The presentation will focus on year-to-year variations in elements of the carbon cycle, specifically on how the observations can inform the representation of mechanisms in the model and lead to integrity in global carbon dioxide simulations. Further, applications of the GEOS model to the planning of new carbon-climate observations will be addressed, as an example of the work that was strongly supported by Piers in the last months of his leadership of Earth Science at NASA Goddard.

  11. Logistics Reduction and Repurposing Beyond Low Earth Orbit

    NASA Technical Reports Server (NTRS)

    Broyan, James Lee, Jr.; Ewert, Michael K.

    2011-01-01

    All human space missions, regardless of destination, require significant logistical mass and volume that is strongly proportional to mission duration. Anything that can be done to reduce initial mass and volume of supplies or reuse items that have been launched will be very valuable. Often, the logistical items require disposal and represent a trash burden. Utilizing systems engineering to analyze logistics from cradle-to-grave and then to potential reuse, can minimize logistics contributions to total mission architecture mass. In NASA's Advanced Exploration Systems Logistics Reduction and Repurposing Project , various tasks will reduce the intrinsic mass of logistical packaging, enable reuse and repurposing of logistical packaging and carriers for other habitation, life support, crew health, and propulsion functions, and reduce or eliminate the nuisances aspects of trash at the same time. Repurposing reduces the trash burden and eliminates the need for hardware whose function can be provided by use of spent logistic items. However, these reuse functions need to be identified and built into future logical systems to enable them to effectively have a secondary function. These technologies and innovations will help future logistic systems to support multiple exploration missions much more efficiently.

  12. Systemwide board assessment.

    PubMed

    Hafertepe, E C

    1987-01-01

    The Sisters of Charity Health Care System (SCHCS), Inc., Cincinnati, undertook a systemwide board evaluation project to support and enhance effective aspects of governance and to deal with obstacles that often arise due to differing beliefs and role confusion. A task force of chief executive officers developed the questionnaire, which was then administered to members of individual facilities' boards and the system's board. The documented highlighted value issues important to SCHCS's ministry and business activities: overall board responsibilities, financial responsibilities, strategic planning, the board's role, committee structures, the board's operating process, board education, and overall board effectiveness. The responses from each member were returned to the local boards, who analyzed them and developed an action plan. A summary of each facility's responses and action plans were forwarded to the system's corporate office. The CEO committee critiqued the process and reported on significant issues and action plans. In general, survey results revealed a strong influence of mission and philosophy in decision making, support for current processes, and effective interaction among board members. The system's corporate office will use the responses to respond to a dynamic environment and strengthen their role in the delivery of Catholic health care services.

  13. First principles-based moiré model for incommensurate graphene on BN

    NASA Astrophysics Data System (ADS)

    Spataru, Catalin; Thurmer, Konrad

    Various properties of supported graphene films depend strongly on the exact positions of carbon atoms with respect to the underlying substrate. While density functional theory (DFT) can predict atom position in many systems, it cannot be applied straightforwardly to systems that are incommensurate or have large unit cells, such as graphene on a BN surface. We address these limitations by developing a simple moiré model with parameters derived from DFT calculations for systems strained into commensurate structures with manageable unit cell sizes. Our moiré model, which takes into account the flexural rigidity of graphene and includes the influence of the substrate, is able to reproduce the DFT-relaxed carbon positions with an accuracy of <0.01 Å. We then apply this model to the unstrained C/BN system and predict how structure and energy vary with azimuthal orientation of the graphene sheet with respect to the BN substrate. Work supported by the Laboratory Directed Research and Development program at Sandia National Laboratories, a multi-program laboratory operated by Sandia Corporation, a Lockheed Martin Co., for the U.S. DOE under Contract DE-AC04-94AL85000.

  14. Written language impairments in primary progressive aphasia: a reflection of damage to central semantic and phonological processes.

    PubMed

    Henry, Maya L; Beeson, Pélagie M; Alexander, Gene E; Rapcsak, Steven Z

    2012-02-01

    Connectionist theories of language propose that written language deficits arise as a result of damage to semantic and phonological systems that also support spoken language production and comprehension, a view referred to as the "primary systems" hypothesis. The objective of the current study was to evaluate the primary systems account in a mixed group of individuals with primary progressive aphasia (PPA) by investigating the relation between measures of nonorthographic semantic and phonological processing and written language performance and by examining whether common patterns of cortical atrophy underlie impairments in spoken versus written language domains. Individuals with PPA and healthy controls were administered a language battery, including assessments of semantics, phonology, reading, and spelling. Voxel-based morphometry was used to examine the relation between gray matter volumes and language measures within brain regions previously implicated in semantic and phonological processing. In accordance with the primary systems account, our findings indicate that spoken language performance is strongly predictive of reading/spelling profile in individuals with PPA and suggest that common networks of critical left hemisphere regions support central semantic and phonological processes recruited for spoken and written language.

  15. Obama Reiterates Strong Support for Science at Two Recent Appearances

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2013-05-01

    President Barack Obama expressed his continued strong support for science and technology in remarks at the U.S. National Academy of Sciences (NAS) on 29 April. His call for continued funding, for scientific integrity, and for an "all-hands-on-deck" approach to science, technology, engineering, and mathematics (STEM) followed remarks he made a week earlier at the White House Science Fair.

  16. Community And Stakeholder Engagement With A University-Based Storm Research Team And Program During Events: Progressive Awareness, Cooperation And Mutual Support.

    NASA Astrophysics Data System (ADS)

    Gayes, P. T.; Bao, S.; Yan, T.; Pietrafesa, L. J.; Hallstrom, J.; Stirling, D.; Mullikin, T.; McClam, M.; Byrd, M.; Aucoin, K.; Marosites, B.

    2017-12-01

    HUGO: The HUrricane Genesis and Outlook program is a research initiative spanning new approaches to Atlantic tropical season outlooking to a storm event-related interactively coupled model system. In addition to supporting faculty and student academic research it has progressively been engaged by diverse regional interests in the public and private sector. The seasonal outlook incorporates 22 regional-to-global climate drivers developed from the historical storm database and has shown good skill related to historical storm seasons within the development of the model as well as the last several years in an outlook capacity. The event scale model is a based upon a fully interactively coupled model system incorporating ocean, atmosphere, wave and surge/flood models. The recent cluster of storms impacting the Southeast US provided an opportunity to test the model system and helped develop strong collaborative interests across diverse groups seeking to facilitate local capacity and access to additional storm-related information, observations and expertise. The SC State Guard has actively engaged the HUGO team in carrying out their charge in emergency responders planning and activities during several recent storms and flooding events. They were instrumental in developing support to expand observational systems aiding model validation and development as well as develop access pathways for deployment of new observational technology developed through NSF sponsored projects (Intelligent River and Hurricane-RAPID) with ISENSE at Florida Atlantic University to advance observational capability and density especially during or immediately following events. At the same time an increasing number of county-level emergency and environmental managers and private sector interests have similarly been working collaborately towards expanding observational systems contributing to the goals of the growing storm-oriented cooperative and as well as broader national MesoUS goals. Collectively, the interaction and partnering have aided and advanced diverse interests, enabled direct and in-kind support towards mutual goals and enabled considerable leverage of resources focused on science and supporting applications.

  17. The Relationship between Teacher Support and Students' Academic Emotions: A Meta-Analysis

    PubMed Central

    Lei, Hao; Cui, Yunhuo; Chiu, Ming Ming

    2018-01-01

    This meta-analysis examines the association between teacher support and students' academic emotions [both positive academic emotions (PAEs) and negative academic emotions (NAEs)] and explores how student characteristics moderate these relationships. We identified 65 primary studies with 58,368 students. The results provided strong evidence linking teacher support and students' academic emotions. Furthermore, students' culture, age, and gender moderated these links. The correlation between teacher support and PAEs was stronger for Western European and American students than for East Asian students, while the correlation between teacher support and NAEs was stronger for East Asian students than for Western European and American students. Also, the correlation between teacher support and PAEs was strong among university students and weaker among middle school students, compared to other students. The correlation between teacher support and NAEs was stronger for middle school students and for female students, compared to other students. PMID:29403405

  18. z~2: An Epoch of Disk Assembly

    NASA Astrophysics Data System (ADS)

    Simons, Raymond C.; Kassin, Susan A.; Weiner, Benjamin; Heckman, Timothy M.; Trump, Jonathan; SIGMA, DEEP2

    2018-01-01

    At z = 0, the majority of massive star-forming galaxies contain thin, rotationally supported gas disks. It was once accepted that galaxies form thin disks early: collisional gas with high velocity dispersion should dissipate energy, conserve angular momentum, and develop strong rotational support in only a few galaxy crossing times (~few hundred Myr). However, this picture is complicated at high redshift, where the processes governing galaxy assembly tend to be violent and inhospitable to disk formation. We present results from our SIGMA survey of star-forming galaxy kinematics at z = 2. These results challenge the simple picture described above: galaxies at z = 2 are unlike local well-ordered disks. Their kinematics tend to be much more disordered, as quantified by their low ratios of rotational velocity to gas velocity dispersion (Vrot/σg): less than 35% of galaxies have Vrot/σg > 3. For comparison, nearly 100% of local star-forming galaxies meet this same threshold. We combine our high redshift sample with a similar low redshift sample from the DEEP2 survey. This combined sample covers a continuous redshift baseline over 0.1 < z < 2.5, spanning 10 Gyrs of cosmic time. Over this period, galaxies exhibit remarkably smooth kinematic evolution on average. All galaxies tend towards rotational support with time, and it is reached earlier in higher mass systems. This is due to both a significant decline in gas velocity dispersion and a mild rise in ordered rotational motions. These results indicate that z = 2 is a period of disk assembly, during which the strong rotational support present in today’s massive disk galaxies is only just beginning to emerge.

  19. Facilitators and barriers to application of the Canadian C-spine rule by emergency department triage nurses.

    PubMed

    Clement, Catherine M; Stiell, Ian G; Lowe, Maureen A; Brehaut, Jamie C; Calder, Lisa A; Vaillancourt, Christian; Perry, Jeffrey J

    2016-07-01

    We recently conducted a multicentre implementation study on the use of the Canadian C-Spine Rule (CCR) by emergency department (ED) nurses to clear the c-spine in alert and stable trauma patients (n = 4506). The objective of this study was to conduct a survey of nurses, physicians, and administrators to evaluate their views on the facilitators and barriers to the implementation of the CCR. We conducted both a paper-based and an electronic survey of the three different ED hospital staff groups of nine large teaching hospitals in Ontario, including six regional trauma centres. The content of this survey was informed by a qualitative evaluation of the opinions of the study nurses who had participated in the validation study. 57.5% (281/489) ED triage nurses, 50.2% ED physicians, and 82.8% of administrators responded. Nurse responses most often showed support from manager/educators and teamwork between physicians, nurses, and managers as being important facilitators to the use of the CCR. Physician responses most often identified the importance of a nurse leader/champion/educator, and presence of strong physician leaders. Administrator responses indicated the importance of nurse educators/champions, nurse engagement, and educational support. Barriers indicated by all three groups included busy department, lack of physician support, and lack of nursing support. Bringing about change in clinical practice is complex. Strong leadership, effective communication, and senior physician buy-in appear to be very important. Identification of system-specific barriers and facilitators are important components of successful knowledge translation. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Aligning the Measurement of Microbial Diversity with Macroecological Theory

    DOE PAGES

    Stegen, James C.; Hurlbert, Allen H.; Bond-Lamberty, Ben; ...

    2016-09-23

    The number of microbial operational taxonomic units (OTUs) within a community is akin to species richness within plant/animal (‘macrobial’) systems. A large literature documents OTU richness patterns, drawing comparisons to macrobial theory. There is, however, an unrecognized fundamental disconnect between OTU richness and macrobial theory: OTU richness is commonly estimated on a per-individual basis, while macrobial richness is estimated per-area. Furthermore, the range or extent of sampled environmental conditions can strongly influence a study’s outcomes and conclusions, but this is not commonly addressed when studying OTU richness. Here we (i) propose a new sampling approach that estimates OTU richness per-massmore » of soil, which results in strong support for species energy theory, (ii) use data reduction to show how support for niche conservatism emerges when sampling across a restricted range of environmental conditions, and (iii) show how additional insights into drivers of OTU richness can be generated by combining different sampling methods while simultaneously considering patterns that emerge by restricting the range of environmental conditions. We propose that a more rigorous connection between microbial ecology and macrobial theory can be facilitated by exploring how changes in OTU richness units and environmental extent influence outcomes of data analysis. While fundamental differences between microbial and macrobial systems persist (e.g., species concepts), we suggest that closer attention to units and scale provide tangible and immediate improvements to our understanding of the processes governing OTU richness and how those processes relate to drivers of macrobial species richness.« less

  1. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stegen, James C.; Hurlbert, Allen H.; Bond-Lamberty, Ben

    The number of microbial operational taxonomic units (OTUs) within a community is akin to species richness within plant/animal (‘macrobial’) systems. A large literature documents OTU richness patterns, drawing comparisons to macrobial theory. There is, however, an unrecognized fundamental disconnect between OTU richness and macrobial theory: OTU richness is commonly estimated on a per-individual basis, while macrobial richness is estimated per-area. Furthermore, the range or extent of sampled environmental conditions can strongly influence a study’s outcomes and conclusions, but this is not commonly addressed when studying OTU richness. Here we (i) propose a new sampling approach that estimates OTU richness per-massmore » of soil, which results in strong support for species energy theory, (ii) use data reduction to show how support for niche conservatism emerges when sampling across a restricted range of environmental conditions, and (iii) show how additional insights into drivers of OTU richness can be generated by combining different sampling methods while simultaneously considering patterns that emerge by restricting the range of environmental conditions. We propose that a more rigorous connection between microbial ecology and macrobial theory can be facilitated by exploring how changes in OTU richness units and environmental extent influence outcomes of data analysis. While fundamental differences between microbial and macrobial systems persist (e.g., species concepts), we suggest that closer attention to units and scale provide tangible and immediate improvements to our understanding of the processes governing OTU richness and how those processes relate to drivers of macrobial species richness.« less

  2. Compression-Driven Enhancement of Electronic Correlations in Simple Alkali Metals

    NASA Astrophysics Data System (ADS)

    Fabbris, Gilberto; Lim, Jinhyuk; Veiga, Larissa; Haskel, Daniel; Schilling, James

    2015-03-01

    Alkali metals are the best realization of the nearly free electron model. This scenario appears to change dramatically as the alkalis are subjected to extreme pressure, leading to unexpected properties such as the departure from metallic behavior in Li and Na, and the occurrence of remarkable low-symmetry crystal structures in all alkalis. Although the mechanism behind these phase transitions is currently under debate, these are believed to be electronically driven. In this study the high-pressure electronic and structural ground state of Rb and Cs was investigated through low temperature XANES and XRD measurements combined with ab initio calculations. The results indicate that the pressure-induced localization of the conduction band triggers a Peierls-like mechanism, inducing the low symmetry phases. This localization process is evident by the pressure-driven increase in the number of d electrons, which takes place through strong spd hybridization. These experimental results indicate that compression turns the heavy alkali metals into strongly correlated electron systems. Work at Argonne was supported by DOE No. DE-AC02-06CH11357. Research at Washington University was supported by NSF DMR-1104742 and CDAC/DOE/NNSA DE-FC52-08NA28554.

  3. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gasenzer, Thomas; McLerran, Larry; Pawlowski, Jan M.

    The real-time dynamics of topological defects and turbulent configurations of gauge fields for electric and magnetic confinement are studied numerically within a 2+1D Abelian Higgs model. It is shown that confinement is appearing in such systems equilibrating after a strong initial quench such as the overpopulation of the infrared modes. While the final equilibrium state does not support confinement, metastable vortex defect configurations appearing in the gauge field are found to be closely related to the appearance of physically observable confined electric and magnetic charges. These phenomena are seen to be intimately related to the approach of a non-thermal fixedmore » point of the far-from-equilibrium dynamical evolution, signaled by universal scaling in the gauge-invariant correlation function of the Higgs field. Even when the parameters of the Higgs action do not support condensate formation in the vacuum, during this approach, transient Higgs condensation is observed. We discuss implications of these results for the far-from-equilibrium dynamics of Yang–Mills fields and potential mechanisms of how confinement and condensation in non-Abelian gauge fields can be understood in terms of the dynamics of Higgs models. These suggest that there is an interesting new class of dynamics of strong coherent turbulent gauge fields with condensates.« less

  4. Micro-assembly of three-dimensional rotary MEMS mirrors

    NASA Astrophysics Data System (ADS)

    Wang, Lidai; Mills, James K.; Cleghorn, William L.

    2009-02-01

    We present a novel approach to construct three-dimensional rotary micro-mirrors, which are fundamental components to build 1×N or N×M optical switching systems. A rotary micro-mirror consists of two microparts: a rotary micro-motor and a micro-mirror. Both of the two microparts are fabricated with PolyMUMPs, a surface micromachining process. A sequential robotic microassembly process is developed to join the two microparts together to construct a threedimensional device. In order to achieve high positioning accuracy and a strong mechanical connection, the micro-mirror is joined to the micro-motor using an adhesive mechanical fastener. The mechanical fastener has self-alignment ability and provides a temporary joint between the two microparts. The adhesive bonding can create a strong permanent connection, which does not require extra supporting plates for the micro-mirror. A hybrid manipulation strategy, which includes pick-and-place and pushing-based manipulations, is utilized to manipulation the micro-mirror. The pick-andplace manipulation has the ability to globally position the micro-mirror in six degrees of freedom. The pushing-based manipulation can achieve high positioning accuracy. This microassembly approach has great flexibility and high accuracy; furthermore, it does not require extra supporting plates, which greatly simplifies the assembly process.

  5. CO oxidation on Ru-Pt bimetallic nanoclusters supported on TiO2(101): The effect of charge polarization

    NASA Astrophysics Data System (ADS)

    Jia, Chuanyi; Zhong, Wenhui; Deng, Mingsen; Jiang, Jun

    2018-03-01

    Pt-based catalyst is widely used in CO oxidation, while its catalytic activity is often undermined because of the CO poisoning effect. Here, using density functional theory, we propose the use of a Ru-Pt bimetallic cluster supported on TiO2 for CO oxidation, to achieve both high activity and low CO poisoning effect. Excellent catalytic activity is obtained in a Ru1Pt7/TiO2(101) system, which is ascribed to strong electric fields induced by charge polarization between one Ru atom and its neighboring Pt atoms. Because of its lower electronegativity, the Ru atom donates electrons to neighboring Pt. This induces strong electric fields around the top-layered Ru, substantially promoting the adsorption of O2/CO + O2 and eliminating the CO poisoning effect. In addition, the charge polarization also drives the d-band center of the Ru1Pt7 cluster to up-shift to the Fermi level. For surface O2 activation/CO oxidation, the strong electric field and d-band center close to the Fermi level can promote the adsorption of O2 and CO as well as reduce the reaction barrier of the rate-determining step. Meanwhile, since O2 easily dissociates on Ru1Pt7/TiO2(101) resulting in unwanted oxidation of Ru and Pt, a CO-rich condition is necessary to protect the catalyst at high temperature.

  6. In vitro comparison of support capabilities of intra-aortic balloon pump and Impella 2.5 left percutaneous.

    PubMed

    Schampaert, Stéphanie; van't Veer, Marcel; van de Vosse, Frans N; Pijls, Nico H J; de Mol, Bas A; Rutten, Marcel C M

    2011-09-01

    The Impella 2.5 left percutaneous (LP), a relatively new transvalvular assist device, challenges the position of the intra-aortic balloon pump (IABP), which has a long record in supporting patients after myocardial infarction and cardiac surgery. However, while more costly and more demanding in management, the advantages of the Impella 2.5 LP are yet to be established. The aim of this study was to evaluate the benefits of the 40 cc IABP and the Impella 2.5 LP operating at 47,000 rpm in vitro, and compare their circulatory support capabilities in terms of cardiac output, coronary flow, cardiac stroke work, and arterial blood pressure. Clinical scenarios of cardiogenic preshock and cardiogenic shock (CS), with blood pressure depression, lowered cardiac output, and constant heart rate of 80 bpm, were modeled in a model-controlled mock circulation, featuring a systemic, pulmonary, and coronary vascular bed. The ventricles, represented by servomotor-operated piston pumps, included the Frank-Starling mechanism. The systemic circulation was modeled with a flexible tube having close-to-human aortic dimensions and compliance properties. Proximally, it featured a branch mimicking the brachiocephalic arteries and a physiological correct coronary flow model. The rest of the systemic and pulmonary impedance was modeled by four-element Windkessel models. In this system, the enhancement of coronary flow and blood pressure was tested with both support systems under healthy and pathological conditions. Hemodynamic differences between the IABP and the Impella 2.5 LP were small. In our laboratory model, both systems approximately yielded a 10% cardiac output increase and a 10% coronary flow increase. However, since the Impella 2.5 LP provided significantly better left ventricular unloading, the circulatory support capabilities were slightly in favor of the Impella 2.5 LP. On the other hand, pulsatility was enhanced with the IABP and lowered with the Impella 2.5 LP. The support capabilities of both the IABP and the Impella 2.5 LP strongly depended on the simulated hemodynamic conditions. Maximum hemodynamic benefits were achieved when mechanical circulatory support was applied on a simulated scenario of deep CS. © 2011, Copyright Eindhoven University of Technology (TU/e). Artificial Organs © 2011, International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

  7. High-order Path Integral Monte Carlo methods for solving strongly correlated fermion problems

    NASA Astrophysics Data System (ADS)

    Chin, Siu A.

    2015-03-01

    In solving for the ground state of a strongly correlated many-fermion system, the conventional second-order Path Integral Monte Carlo method is plagued with the sign problem. This is due to the large number of anti-symmetric free fermion propagators that are needed to extract the square of the ground state wave function at large imaginary time. In this work, I show that optimized fourth-order Path Integral Monte Carlo methods, which uses no more than 5 free-fermion propagators, in conjunction with the use of the Hamiltonian energy estimator, can yield accurate ground state energies for quantum dots with up to 20 polarized electrons. The correlations are directly built-in and no explicit wave functions are needed. This work is supported by the Qatar National Research Fund NPRP GRANT #5-674-1-114.

  8. Electron spin control and spin-libration coupling of a levitated nanodiamond

    NASA Astrophysics Data System (ADS)

    Hoang, Thai; Ma, Yue; Ahn, Jonghoon; Bang, Jaehoon; Robicheaux, Francis; Gong, Ming; Yin, Zhang-Qi; Li, Tongcang

    2017-04-01

    Hybrid spin-mechanical systems have great potentials in sensing, macroscopic quantum mechanics, and quantum information science. Recently, we optically levitated a nanodiamond and demonstrated electron spin control of its built-in nitrogen-vacancy (NV) centers in vacuum. We also observed the libration (torsional vibration) of a nanodiamond trapped by a linearly polarized laser beam in vacuum. We propose to achieve strong coupling between the electron spin of a NV center and the libration of a levitated nanodiamond with a uniform magnetic field. With a uniform magnetic field, multiple spins can couple to the torsional vibration at the same time. We propose to use this strong coupling to realize the Lipkin-Meshkov-Glick (LMG) model and generate rotational superposition states. This work is supported by the National Science Foundation under Grant No. 1555035-PHY.

  9. Implementation of a Web-Based Collaborative Process Planning System

    NASA Astrophysics Data System (ADS)

    Wang, Huifen; Liu, Tingting; Qiao, Li; Huang, Shuangxi

    Under the networked manufacturing environment, all phases of product manufacturing involving design, process planning, machining and assembling may be accomplished collaboratively by different enterprises, even different manufacturing stages of the same part may be finished collaboratively by different enterprises. Based on the self-developed networked manufacturing platform eCWS(e-Cooperative Work System), a multi-agent-based system framework for collaborative process planning is proposed. In accordance with requirements of collaborative process planning, share resources provided by cooperative enterprises in the course of collaboration are classified into seven classes. Then a reconfigurable and extendable resource object model is built. Decision-making strategy is also studied in this paper. Finally a collaborative process planning system e-CAPP is developed and applied. It provides strong support for distributed designers to collaboratively plan and optimize product process though network.

  10. Best kept secrets ... First Coast Systems, Inc. (FCS).

    PubMed

    Andrew, W F

    1991-04-01

    The FCS/APaCS system is a viable option for small-to medium-size hospitals (up to 400 beds). The table-driven system takes full advantage of IBM AS/400 computer architecture. A comprehensive application set, provided in an integrated database environment, is adaptable to multi-facility environments. Price/performance appears to be competitive. Commitment to IBM AS/400 environment assures cost-effective hardware platforms backed by IBM support and resources. As an IBM Health Industry Business Partner, FCS (and its clients) benefits from IBM's well-known commitment to quality and service. Corporate emphasis on user involvement and satisfaction, along with a commitment to quality and service for the APaCS systems, assures clients of "leading edge" capabilities in this evolutionary healthcare delivery environment. FCS/APaCS will be a strong contender in selected marketing environments.

  11. On the origin of high-temperature phenomena in Pt/Al2O3.

    PubMed

    Lisitsyn, Alexander S; Yakovina, Olga A

    2018-01-24

    Treatments of Pt/γ-Al 2 O 3 with H 2 under harsh conditions have long been known to strongly influence the properties of this important catalytic system, but the true causes of the high-temperature effects still remain unclear. We have performed a more detailed study of this issue, having used H 2 -TPD as a sensitive probe of metal-support interactions. The experimental results are in accordance with previous studies and demonstrate strong changes in adsorption and catalytic properties of Pt/γ-Al 2 O 3 after high-temperature H 2 treatments, as well as the possibility to reverse the changes, completely or in part, through O 2 and H 2 O treatments. Thorough examination has shown that such behaviour is an intrinsic property of Pt/γ-Al 2 O 3 and cannot be attributed to impurities or experimental artifacts. Moreover, there is no abrupt transition to a high-temperature state, but the system undergoes smooth and gradual changes upon increasing the H 2 -treatment temperature (T TR ), with the changes being already apparent at a T TR of ∼ 300 °C. The results suggest that hydrogen can generate oxygen vacancies on the surface of the support in close vicinity to the Pt particles, and the system appears under equilibrium to be kinetically driven by temperature and thermodynamically driven by the P H 2 /P H 2 O ratio or local concentration of surface hydroxyls near Pt particles. The generated vacancies change the properties of contacting particles, and the changes are most pronounced for sub-nanometric Pt clusters and single atoms. Implications of the phenomena for the synthesis, study, and use of Pt/γ-Al 2 O 3 and its related nanosystems are discussed.

  12. Ritual human sacrifice promoted and sustained the evolution of stratified societies.

    PubMed

    Watts, Joseph; Sheehan, Oliver; Atkinson, Quentin D; Bulbulia, Joseph; Gray, Russell D

    2016-04-14

    Evidence for human sacrifice is found throughout the archaeological record of early civilizations, the ethnographic records of indigenous world cultures, and the texts of the most prolific contemporary religions. According to the social control hypothesis, human sacrifice legitimizes political authority and social class systems, functioning to stabilize such social stratification. Support for the social control hypothesis is largely limited to historical anecdotes of human sacrifice, where the causal claims have not been subject to rigorous quantitative cross-cultural tests. Here we test the social control hypothesis by applying Bayesian phylogenetic methods to a geographically and socially diverse sample of 93 traditional Austronesian cultures. We find strong support for models in which human sacrifice stabilizes social stratification once stratification has arisen, and promotes a shift to strictly inherited class systems. Whilst evolutionary theories of religion have focused on the functionality of prosocial and moral beliefs, our results reveal a darker link between religion and the evolution of modern hierarchical societies.

  13. MINC 2.0: A Flexible Format for Multi-Modal Images.

    PubMed

    Vincent, Robert D; Neelin, Peter; Khalili-Mahani, Najmeh; Janke, Andrew L; Fonov, Vladimir S; Robbins, Steven M; Baghdadi, Leila; Lerch, Jason; Sled, John G; Adalat, Reza; MacDonald, David; Zijdenbos, Alex P; Collins, D Louis; Evans, Alan C

    2016-01-01

    It is often useful that an imaging data format can afford rich metadata, be flexible, scale to very large file sizes, support multi-modal data, and have strong inbuilt mechanisms for data provenance. Beginning in 1992, MINC was developed as a system for flexible, self-documenting representation of neuroscientific imaging data with arbitrary orientation and dimensionality. The MINC system incorporates three broad components: a file format specification, a programming library, and a growing set of tools. In the early 2000's the MINC developers created MINC 2.0, which added support for 64-bit file sizes, internal compression, and a number of other modern features. Because of its extensible design, it has been easy to incorporate details of provenance in the header metadata, including an explicit processing history, unique identifiers, and vendor-specific scanner settings. This makes MINC ideal for use in large scale imaging studies and databases. It also makes it easy to adapt to new scanning sequences and modalities.

  14. Preserving the Finger Lakes for the Future: A Prototype Decision Support System for Water Resource Management, Open Space, and Agricultural Protection

    NASA Technical Reports Server (NTRS)

    Brower, Robert

    2003-01-01

    As described herein, this project has progressed well, with the initiation or completion of a number of program facets at programmatic, technical, and inter-agency levels. The concept of the Virtual Management Operations Center has taken shape, grown, and has been well received by parties from a wide variety of agencies and organizations in the Finger Lakes region and beyond. As it has evolved in design and functionality, and to better illustrate its current focus for this project, it has been given the expanded name of Watershed Virtual Management Operations Center (W-VMOC). It offers the advanced, compelling functionality of interactive 3D visualization interfaced with 2D mapping, all accessed via Internet or virtually any kind of distributed computer network. This strong foundation will allow the development of a Decision Support System (DSS) with anticipated enhanced functionality to be applied to the myriad issues involved in the wise management of the Finger Lakes region.

  15. Children with chronic continence problems: the challenges for families.

    PubMed

    Erickson, David V; Ray, Lynne D

    2004-01-01

    For families who are raising children with myelomeningocele, bowel and bladder incontinence presents unique challenges for everyday life. The Parenting and Childhood Chronicity model is used to describe the work of raising a child with a chronic condition in 6 areas, including medical care, adapted parenting, dealing with the systems, caring for siblings, maintaining relationships, and personal coping (keeping yourself going). This article provides an overview of the physiologic and developmental challenges inherent in this neural tube defect and illustrates the work that is involved in the child's care and the challenges of maintaining a balance in family life. Clinical implications are discussed, including the setting of appropriate expectations, providing parents with accurate information, ensuring that a focus on continence is not at the expense of other important aspects of the child's functioning, and supporting parents in their interaction with the school system. The medical team, consisting of nursing, urology, nephrology, and psychology working together, can be a strong support for families.

  16. Research in support of health systems transformation in South Africa: the experience of the Centre for Health Policy.

    PubMed

    Rispel, Laetitia C; Doherty, Jane

    2011-01-01

    We describe the role and experience of the Centre for Health Policy (CHP), a university-based research unit established in 1987, in influencing and supporting health systems transformation in South Africa over two decades. During 2010, we analyzed relevant documents and conducted interviews with 25 key informants. CHP's research has contributed directly to health policy development and implementation while also changing the way government understood or approached policy issues. Key success factors for policy influence are: research quality and trustworthiness, strategic alliances and networking, and capacity building. CHP's challenges include identifying new funding sources and sustaining a high public profile. The lessons for other countries are to: conduct good quality, relevant research based on strong ethical values; build and maintain open and honest relationships with government; recognize and adapt to changes in the policy environment; develop capacity as part of a continuous programme; and seek core funding that ensures research independence and public accountability.

  17. Spectral statistics and scattering resonances of complex primes arrays

    NASA Astrophysics Data System (ADS)

    Wang, Ren; Pinheiro, Felipe A.; Dal Negro, Luca

    2018-01-01

    We introduce a class of aperiodic arrays of electric dipoles generated from the distribution of prime numbers in complex quadratic fields (Eisenstein and Gaussian primes) as well as quaternion primes (Hurwitz and Lifschitz primes), and study the nature of their scattering resonances using the vectorial Green's matrix method. In these systems we demonstrate several distinctive spectral properties, such as the absence of level repulsion in the strongly scattering regime, critical statistics of level spacings, and the existence of critical modes, which are extended fractal modes with long lifetimes not supported by either random or periodic systems. Moreover, we show that one can predict important physical properties, such as the existence spectral gaps, by analyzing the eigenvalue distribution of the Green's matrix of the arrays in the complex plane. Our results unveil the importance of aperiodic correlations in prime number arrays for the engineering of gapped photonic media that support far richer mode localization and spectral properties compared to usual periodic and random media.

  18. Quantum carpets in a one-dimensional tilted optical lattices

    NASA Astrophysics Data System (ADS)

    Parra Murillo, Carlos Alberto; Muã+/-Oz Arias, Manuel Humberto; Madroã+/-Ero, Javier

    A unit filling Bose-Hubbard Hamiltonian embedded in a strong Stark field is studied in the off-resonant regime inhibiting single- and many-particle first-order tunneling resonances. We investigate the occurrence of coherent dipole wavelike propagation along an optical lattice by means of an effective Hamiltonian accounting for second-order tunneling processes. It is shown that dipole wave function evolution in the short-time limit is ballistic and that finite-size effects induce dynamical self-interference patterns known as quantum carpets. We also present the effects of the border right after the first reflection, showing that the wave function diffuses normally with the variance changing linearly in time. This work extends the rich physical phenomenology of tilted one-dimensional lattice systems in a scenario of many interacting quantum particles, the so-called many-body Wannier-Stark system. The authors acknownledge the finantial support of the Universidad del Valle (project CI 7996). C. A. Parra-Murillo greatfully acknowledges the financial support of COLCIENCIAS (Grant 656).

  19. Chinese perceptions of the interface between school and museum education

    NASA Astrophysics Data System (ADS)

    Kang, Changyun; Anderson, David; Wu, Xinchun

    2010-09-01

    The current political and social backdrop in China that is characterized by rapid educational reforms to the K-12 education system, rapid growth in the number of science museum institutions, and Central Government policy which encourages collaboration between museums and school has the potential to be fertile ground for meaningful engagement between museums and schools. Notwithstanding, the Chinese K-12 education system generally does not utilize museum resources to support the curriculum, as is common in Western countries. This hermeneutic phenomenographic study elucidates the current Chinese views and perceptions among three stakeholders—school teachers, museum staffs and science educators—around this collaborative concept. The outcomes demonstrate that strongly entrenched cultural views and long-standing practices among stakeholder groups are obstacles to meaningful collaboration despite Central Government policy which encourages such engagement. The cultural values and perceptual views of stakeholder groups were discerned with the purpose of promoting mutual understandings and ultimately enabling meaningful collaboration in support of K-12 education in China.

  20. Rapid onset of decoherence in driven-dissipative Rydberg systems

    NASA Astrophysics Data System (ADS)

    Magnan, Eric; Boulier, Thomas; Bracamontes, Carlos; Maslek, James; Young, Jeremy; Gorshkov, Alexei; Porto, Trey; Rolston, Steven; JQI-Rubidium One Team

    2017-04-01

    Rydberg atoms have been strong candidates for the realization of quantum information processing and quantum simulation. Recently, however, there has been concerns about this approach due to the observation of a rapid onset of decoherence in large ensembles. In we provide experimental support for the hypothesis that this is due to the avalanche-like onset of exchange dipole interactions, fueled by blackbody transitions to nearby Rydberg states of opposite parity. Making a fully microscopic model has proven difficult as it requires beyond mean-field arguments, but the ubiquitousness of Rydberg-Rydberg blackbody transitions at room temperature and the always-resonant nature of dipole exchange interactions make it an interesting challenge, and argues for deeper study into the matter. In this poster, we present complementary measurements and analysis that confirm this mechanism. We also discuss several possibilities to reduce its impact on the system's coherence. This work was partially supported by NSF PIF, AFOSR, ARO, ARL-CDQI, and NSF PFC at JQI.

  1. Evaluating Motivational Enhancement Therapy Adherence and Competence Among Spanish-speaking Therapists

    PubMed Central

    Santa Ana, Elizabeth J.; Carroll, Kathleen M.; Añez, Luis; Paris, Manuel; Ball, Samuel A.; Nich, Charla; Frankforter, Tami L.; Suarez-Morales, Lourdes; Szapocznik, José; Martino, Steve

    2009-01-01

    Despite the fact that the number of Hispanic individuals in need of treatment for substance use problems is increasing internationally, no studies have investigated the extent to which therapists can provide empirically supported treatments to Spanish-speaking clients with adequate fidelity. Twenty-three bilingual Hispanic therapists from five community outpatient treatment programs in the United States were randomly assigned to deliver either three sessions of motivational enhancement therapy (MET) or an equivalent number of drug counseling-as-usual sessions (CAU) in Spanish to 405 Spanish-speaking clients randomly assigned to these conditions. Independent ratings of 325 sessions indicated the adherence/competence rating system had good to excellent interrater reliability and indicated strong support for an a priori defined fundamental MET skill factor. Support for an advanced MET skill factor was relatively weaker. The rating scale indicated significant differences in therapists’ MET adherence and competence across conditions. These findings indicate that the rating system has promise for assessing the performance of therapists who deliver MET in Spanish and suggest that bilingual Spanish-speaking therapists from the community can be trained to implement MET with adequate fidelity and skill using an intensive multisite training and supervision model. PMID:19394164

  2. Radio emission from RS CVn binaries. II - Polarization and spectral properties

    NASA Technical Reports Server (NTRS)

    Mutel, R. L.; Morris, D. H.; Doiron, D. J.; Lestrade, J. F.

    1987-01-01

    Multiepoch radio observations of circular polarization and spectral characteristics of several close, late-type stellar binaries are reported. The median luminosity of four well-studied systems ranged from 16.2 to 17.1 ergs/s/Hz. For individual systems, the fractional circular polarization decreases with increasing luminosity, particularly at frequencies above 5 GHz. Eclipsing binaries have significantly lower average circular polarization compared with noneclipsing systems. Helicity reversal is almost always observed between 1.4 and 4.9 GHz for systems with high orbital inclination. Comparison with ten years of previously published polarization observations for two RS CVn stellar systems show that the same helicity occurs at a given frequency for a given source, indicating a very stable, large-scale magnetic field geometry. These spectral and polarization characteristics strongly support a model of inhomogeneous gyrosynchrotron emission arising from electrons with power law energy spectra interacting with inhomogeneous magnetic fields.

  3. The change-makers of West Africa.

    PubMed

    Godt, Sue; Mhatre, Sharmila; Schryer-Roy, Anne-Marie

    2017-07-12

    West Africa was the focus of global attention during the Ebola virus disease outbreak, when systemic health system weaknesses compounded a serious emergency and complicated response efforts. Following the crisis, calls were made to strengthen health systems, but investments to date have fallen short of delivering the support needed to build strong health systems able to prevent and manage future outbreaks.In part, this reality serves to highlight the shortcomings of the solutions being repeatedly prioritised by external funders and experts, solutions that often fail to consider the wealth of West African evidence and actors actively working to strengthen the leadership and health systems needed to drive and sustainably improve national health outcomes. Unfortunately, this knowledge and experience are rarely heard in the global arena.This journal supplement is a contribution, although small, to changing this practice by putting the perspectives, experiences and knowledge of West Africans on the table. It presents findings from a series of research and capacity development projects in West Africa funded by the International Development Research Centre's Maternal and Child Health programme (formerly Governance for Equity in Health Systems).The evidence presented here centres around two key themes. First, the theme that context matters. The evidence shows how context can change the shape of externally imposed interventions or policies resulting in unintended outcomes. At the same time, it highlights evidence showing how innovative local actors are developing their own approaches, usually low-cost and embedded in the context, to bring about change. Second, the collection of articles discusses the critical need to overcome the existing fragmentation of expertise, knowledge and actors, and to build strong working relationships amongst all actors so they can effectively work together to identify priority issues that can realistically be addressed given the available windows of opportunity.Vibrant West African-led collaborations amongst researchers, decision-makers and civil society, which are effectively supported by national, regional and global funding, need to foster, strengthen and use locally-generated evidence to ensure that efforts to strengthen health systems and improve regional health outcomes are successful. The solutions are clearly not to be found in the 'travelling models' of standardised interventions.

  4. Customer service providers' attitudes relating to customer service and customer satisfaction in the customer-server exchange.

    PubMed

    Susskind, Alex M; Kacmar, K Michele; Borchgrevink, Carl P

    2003-02-01

    The authors proposed and tested a model describing the relationship between customer service providers' perceptions and attitudes toward their service-related duties and their customers' perceptions of satisfaction with their service experiences. Results indicated that the perception of having standards for service delivery in an organization is strongly related to line-level employees' perceptions of support from coworkers and supervisors. Perceived support from coworkers was significantly related to service providers' customer orientation, whereas perceived support from supervisors showed a weaker relationship to a customer orientation. Ultimately, service providers' customer orientation was strongly related to customers' satisfaction with service. Finally, a set of post hoc analyses indicated that coworker and supervisory support explained a greater proportion of incremental variance in the model than did perceived organizational support alone.

  5. 13 CFR 301.8 - Proposal evaluation criteria.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Investment. (b) Has strong organizational leadership. An Investment will have strong leadership, relevant... private sector leverage; (2) Clear and unified leadership and support by local elected officials; and (3...

  6. Hydrogen Production by Steam Reforming of Ethanol over Nickel Catalysts Supported on Sol Gel Made Alumina: Influence of Calcination Temperature on Supports

    PubMed Central

    Yaakob, Zahira; Bshish, Ahmed; Ebshish, Ali; Tasirin, Siti Masrinda; Alhasan, Fatah H.

    2013-01-01

    Selecting a proper support in the catalyst system plays an important role in hydrogen production via ethanol steam reforming. In this study, sol gel made alumina supports prepared for nickel (Ni) catalysts were calcined at different temperatures. A series of (Ni/AlS.G.) catalysts were synthesized by an impregnation procedure. The influence of varying the calcination temperature of the sol gel made supports on catalyst activity was tested in ethanol reforming reaction. The characteristics of the sol gel alumina supports and Ni catalysts were affected by the calcination temperature of the supports. The structure of the sol gel made alumina supports was transformed in the order of γ → (γ + θ) → θ-alumina as the calcination temperature of the supports increased from 600 °C to 1000 °C. Both hydrogen yield and ethanol conversion presented a volcano-shaped behavior with maximum values of 4.3 mol/mol ethanol fed and 99.5%, respectively. The optimum values were exhibited over Ni/AlS.G800 (Ni catalyst supported on sol gel made alumina calcined at 800 °C). The high performance of the Ni/AlS.G800 catalyst may be attributed to the strong interaction of Ni species and sol gel made alumina which lead to high nickel dispersion and small particle size. PMID:28809270

  7. Hydrogen Production by Steam Reforming of Ethanol over Nickel Catalysts Supported on Sol Gel Made Alumina: Influence of Calcination Temperature on Supports.

    PubMed

    Yaakob, Zahira; Bshish, Ahmed; Ebshish, Ali; Tasirin, Siti Masrinda; Alhasan, Fatah H

    2013-05-30

    Selecting a proper support in the catalyst system plays an important role in hydrogen production via ethanol steam reforming. In this study, sol gel made alumina supports prepared for nickel (Ni) catalysts were calcined at different temperatures. A series of (Ni/Al S.G. ) catalysts were synthesized by an impregnation procedure. The influence of varying the calcination temperature of the sol gel made supports on catalyst activity was tested in ethanol reforming reaction. The characteristics of the sol gel alumina supports and Ni catalysts were affected by the calcination temperature of the supports. The structure of the sol gel made alumina supports was transformed in the order of γ → (γ + θ) → θ-alumina as the calcination temperature of the supports increased from 600 °C to 1000 °C. Both hydrogen yield and ethanol conversion presented a volcano-shaped behavior with maximum values of 4.3 mol/mol ethanol fed and 99.5%, respectively. The optimum values were exhibited over Ni/Al S.G800 (Ni catalyst supported on sol gel made alumina calcined at 800 °C). The high performance of the Ni/Al S.G800 catalyst may be attributed to the strong interaction of Ni species and sol gel made alumina which lead to high nickel dispersion and small particle size.

  8. Dentistry students' perceptions of learning management systems.

    PubMed

    Handal, B; Groenlund, C; Gerzina, T

    2010-02-01

    This paper reports an exploratory survey study about students' perceptions of learning management systems (LMS) at the Faculty of Dentistry, University of Sydney. Two hundred and fifty-four students enrolled in the Bachelor of Dentistry and the Bachelor of Oral Health programmes participated in an online survey aimed at exploring their beliefs and attitudes as well as their preferences for eLearning tools. Results indicated a strong preference of students for using LMSs as resource repositories rather than for higher-order learning activities such as online discussion forums. This finding holds importance for consideration of the development of the educational resources modalities that support development of essential graduate attributes such as information literacy and collaborative learning.

  9. Antenna grout replacement system

    NASA Technical Reports Server (NTRS)

    Mcclung, C. E. (Inventor)

    1983-01-01

    An epoxy grout suitable for use in mounting and positioning bearing runner plates used in hydrostatic bearing assemblies for rotatably mounting large radio telescope structures to stationary support pedestals is described. The epoxy grout may be used in original mountings or may be used as part of a replacement system for repairing cavities in existing grout resulting from grout deterioration. The epoxy grout has a relatively short work life and cure time even in the presence of hydraulic oil. The epoxy grout cures without shrinking or sagging to form a grout which is sufficiently strong and durable to provide a grout especially well suited for use under the high pressure loading and close tolerance requirements of large hydrostatic bearing assemblies.

  10. Meta-T: TetrisⓇ as an experimental paradigm for cognitive skills research.

    PubMed

    Lindstedt, John K; Gray, Wayne D

    2015-12-01

    Studies of human performance in complex tasks using video games are an attractive prospect, but many existing games lack a comprehensive way to modify the game and track performance beyond basic levels of analysis. Meta-T provides experimenters a tool to study behavior in a dynamic task environment with time-stressed decision-making and strong perceptual-motor elements, offering a host of experimental manipulations with a robust and detailed logging system for all user events, system events, and screen objects. Its experimenter-friendly interface provides control over detailed parameters of the task environment without need for programming expertise. Support for eye-tracking and computational cognitive modeling extend the paradigm's scope.

  11. The formation of the planetary system

    NASA Astrophysics Data System (ADS)

    Tscharnuter, W. M.

    1984-12-01

    The basic ideas concerning solar system formation were developed by Kant (1755) and Laplace (1796) whose starting point was the so-called nebular hypothesis. The great advantage of the nebular hypothesis is that many regularities, e.g. prograde motions of all planets and asteroids in almost coplanar orbits, can be explained. Observations in the radio and infrared region strongly support the nebular hypothesis provided that the angular momentum problem can be solved in some way. Three possibilities are listed: (1) magnetic fields via Alfvén waves which can transport angular momentum from the contracting cloud fragment into the external medium, (2) turbulent friction, (3) gravitational torques exerted by high amplitude spiral or bar-like density waves in the nebula.

  12. Frequency dependence and passive drains in fish-eye lenses

    NASA Astrophysics Data System (ADS)

    Quevedo-Teruel, O.; Mitchell-Thomas, R. C.; Hao, Y.

    2012-11-01

    The Maxwell fish eye lens has previously been reported as being capable of the much sought after phenomenon of subwavelength imaging. The inclusion of a drain in this system is considered crucial to the imaging ability, although its role is the topic of much debate. This paper provides a numerical investigation into a practical implementation of a drain in such systems, and analyzes the strong frequency dependence of both the Maxwell fish eye lens and an alternative, the Miñano lens. The imaging capability of these types of lens is questioned, and it is supported by simulations involving various configurations of drain arrays. Finally, a discussion of the near-field and evanescent wave contribution is given.

  13. AphidBase: A centralized bioinformatic resource for annotation of the pea aphid genome

    PubMed Central

    Legeai, Fabrice; Shigenobu, Shuji; Gauthier, Jean-Pierre; Colbourne, John; Rispe, Claude; Collin, Olivier; Richards, Stephen; Wilson, Alex C. C.; Tagu, Denis

    2015-01-01

    AphidBase is a centralized bioinformatic resource that was developed to facilitate community annotation of the pea aphid genome by the International Aphid Genomics Consortium (IAGC). The AphidBase Information System designed to organize and distribute genomic data and annotations for a large international community was constructed using open source software tools from the Generic Model Organism Database (GMOD). The system includes Apollo and GBrowse utilities as well as a wiki, blast search capabilities and a full text search engine. AphidBase strongly supported community cooperation and coordination in the curation of gene models during community annotation of the pea aphid genome. AphidBase can be accessed at http://www.aphidbase.com. PMID:20482635

  14. GRAPES-Grounding representations in action, perception, and emotion systems: How object properties and categories are represented in the human brain.

    PubMed

    Martin, Alex

    2016-08-01

    In this article, I discuss some of the latest functional neuroimaging findings on the organization of object concepts in the human brain. I argue that these data provide strong support for viewing concepts as the products of highly interactive neural circuits grounded in the action, perception, and emotion systems. The nodes of these circuits are defined by regions representing specific object properties (e.g., form, color, and motion) and thus are property-specific, rather than strictly modality-specific. How these circuits are modified by external and internal environmental demands, the distinction between representational content and format, and the grounding of abstract social concepts are also discussed.

  15. A data-assimilative ocean forecasting system for the Prince William sound and an evaluation of its performance during sound Predictions 2009

    NASA Astrophysics Data System (ADS)

    Farrara, John D.; Chao, Yi; Li, Zhijin; Wang, Xiaochun; Jin, Xin; Zhang, Hongchun; Li, Peggy; Vu, Quoc; Olsson, Peter Q.; Schoch, G. Carl; Halverson, Mark; Moline, Mark A.; Ohlmann, Carter; Johnson, Mark; McWilliams, James C.; Colas, Francois A.

    2013-07-01

    The development and implementation of a three-dimensional ocean modeling system for the Prince William Sound (PWS) is described. The system consists of a regional ocean model component (ROMS) forced by output from a regional atmospheric model component (the Weather Research and Forecasting Model, WRF). The ROMS ocean model component has a horizontal resolution of 1km within PWS and utilizes a recently-developed multi-scale 3DVAR data assimilation methodology along with freshwater runoff from land obtained via real-time execution of a digital elevation model. During the Sound Predictions Field Experiment (July 19-August 3, 2009) the system was run in real-time to support operations and incorporated all available real-time streams of data. Nowcasts were produced every 6h and a 48-h forecast was performed once a day. In addition, a sixteen-member ensemble of forecasts was executed on most days. All results were published at a web portal (http://ourocean.jpl.nasa.gov/PWS) in real time to support decision making.The performance of the system during Sound Predictions 2009 is evaluated. The ROMS results are first compared with the assimilated data as a consistency check. RMS differences of about 0.7°C were found between the ROMS temperatures and the observed vertical profiles of temperature that are assimilated. The ROMS salinities show greater discrepancies, tending to be too salty near the surface. The overall circulation patterns observed throughout the Sound are qualitatively reproduced, including the following evolution in time. During the first week of the experiment, the weather was quite stormy with strong southeasterly winds. This resulted in strong north to northwestward surface flow in much of the central PWS. Both the observed drifter trajectories and the ROMS nowcasts showed strong surface inflow into the Sound through the Hinchinbrook Entrance and strong generally northward to northwestward flow in the central Sound that was exiting through the Knight Island Passage and Montague Strait entrance. During the latter part of the second week when surface winds were light and southwesterly, the mean surface flow at the Hinchinbrook Entrance reversed to weak outflow and a cyclonic eddy formed in the central Sound. Overall, RMS differences between ROMS surface currents and observed HF radar surface currents in the central Sound were generally between 5 and 10cm/s, about 20-40% of the time mean current speeds.The ROMS reanalysis is then validated against independent observations. A comparison of the ROMS currents with observed vertical current profiles from moored ADCPs in the Hinchinbrook Entrance and Montague Strait shows good qualitative agreement and confirms the evolution of the near surface inflow/outflow at these locations described above. A comparison of the ROMS surface currents with drifter trajectories provided additional confirmation that the evolution of the surface flow described above was realistic. Forecasts of drifter locations had RMS errors of less than 10km for up to 36h. One and two-day forecasts of surface temperature, salinity and current fields were more skillful than persistence forecasts. In addition, ensemble mean forecasts were found to be slightly more skillful than single forecasts. Two case studies demonstrated the system's qualitative skill in predicting subsurface changes within the mixed layer measured by ships and autonomous underwater vehicles. In summary, the system is capable of producing a realistic evolution of the near-surface circulation within PWS including forecasts of up to two days of this evolution. Use of the products provided by the system during the experiment as part of the asset deployment decision making process demonstrated the value of accurate regional ocean forecasts in support of field experiments.

  16. Enhancing Collaborative Learning through Dynamic Forms of Support: The Impact of an Adaptive Domain-Specific Support Strategy

    ERIC Educational Resources Information Center

    Karakostas, A.; Demetriadis, S.

    2011-01-01

    Research on computer-supported collaborative learning (CSCL) has strongly emphasized the value of providing student support of either fixed (e.g. collaboration scripts) or dynamic form (e.g. adaptive supportive interventions). Currently, however, there is not sufficient evidence corroborating the potential of adaptive support methods to improve…

  17. Matrix-product-state method with local basis optimization for nonequilibrium electron-phonon systems

    NASA Astrophysics Data System (ADS)

    Heidrich-Meisner, Fabian; Brockt, Christoph; Dorfner, Florian; Vidmar, Lev; Jeckelmann, Eric

    We present a method for simulating the time evolution of quasi-one-dimensional correlated systems with strongly fluctuating bosonic degrees of freedom (e.g., phonons) using matrix product states. For this purpose we combine the time-evolving block decimation (TEBD) algorithm with a local basis optimization (LBO) approach. We discuss the performance of our approach in comparison to TEBD with a bare boson basis, exact diagonalization, and diagonalization in a limited functional space. TEBD with LBO can reduce the computational cost by orders of magnitude when boson fluctuations are large and thus it allows one to investigate problems that are out of reach of other approaches. First, we test our method on the non-equilibrium dynamics of a Holstein polaron and show that it allows us to study the regime of strong electron-phonon coupling. Second, the method is applied to the scattering of an electronic wave packet off a region with electron-phonon coupling. Our study reveals a rich physics including transient self-trapping and dissipation. Supported by Deutsche Forschungsgemeinschaft (DFG) via FOR 1807.

  18. Deterministic alternatives to the full configuration interaction quantum Monte Carlo method for strongly correlated systems

    NASA Astrophysics Data System (ADS)

    Tubman, Norm; Whaley, Birgitta

    The development of exponential scaling methods has seen great progress in tackling larger systems than previously thought possible. One such technique, full configuration interaction quantum Monte Carlo, allows exact diagonalization through stochastically sampling of determinants. The method derives its utility from the information in the matrix elements of the Hamiltonian, together with a stochastic projected wave function, which are used to explore the important parts of Hilbert space. However, a stochastic representation of the wave function is not required to search Hilbert space efficiently and new deterministic approaches have recently been shown to efficiently find the important parts of determinant space. We shall discuss the technique of Adaptive Sampling Configuration Interaction (ASCI) and the related heat-bath Configuration Interaction approach for ground state and excited state simulations. We will present several applications for strongly correlated Hamiltonians. This work was supported through the Scientific Discovery through Advanced Computing (SciDAC) program funded by the U.S. Department of Energy, Office of Science, Advanced Scientific Computing Research and Basic Energy Sciences.

  19. STM studies of topological phase transition in (Bi,In)2Se3

    NASA Astrophysics Data System (ADS)

    Zhang, Wenhan; Wang, Xueyun; Cheong, Sang-Wook; Wu, Weida; Weida Wu Team; Sang-Wook Cheong Collaboration

    Topological insulators (TI) are a class of materials with insulating bulk and metallic surface state, which is the result of band inversion induced by strong spin-orbit coupling (SOC). The transition from topological phase to non-topological phase is of great significance. In theory, topological phase transition is realized by tuning SOC strength. It is characterized by the process of gap closing and reopening. Experimentally it was observed in two systems: TlBi(S1-xSex)2 and (Bi1-xInx)2 Se3 where the transition is realized by varying isovalent elements doping concentration. However, none of the previous studies addressed the impact of disorder, which is inevitable in doped systems. Here, we present a systematic scanning tunneling microscopy/spectroscopy study on (Bi1-xInx)2 Se3 single crystals with different In concentrations across the transition. Our results reveal an electronic inhomogeneity due to the random distribution of In defects which locally suppress the topological surface states. Our study provides a new angle of understanding the topological transition in the presence of strong disorders. This work is supported by NSF DMR-1506618.

  20. Supporting clinical rules engine in the adjustment of medication (SCREAM): protocol of a multicentre, prospective, randomised study.

    PubMed

    Mestres Gonzalvo, Carlota; de Wit, Hugo A J M; van Oijen, Brigit P C; Hurkens, Kim P G M; Janknegt, Rob; Schols, Jos M G A; Mulder, Wubbo J; Verhey, Frans R; Winkens, Bjorn; van der Kuy, Paul-Hugo M

    2017-01-26

    In the nursing home population, it is estimated that 1 in every 3 patients is polymedicated and given their considerable frailty, these patients are especially prone to adverse drug reactions. Clinical pharmacist-led medication reviews are considered successful interventions to improve medication safety in the inpatient setting. Due to the limited available evidence concerning the benefits of medication reviews performed in the nursing home setting, we propose a study aiming to demonstrate a positive effect that a clinical decision support system, as a health care intervention, may have on the target population. The primary objective of this study is to reduce the number of patients with at least one event when using the clinical decision support system compared to the regular care. These events consist of hospital referrals, delirium, falls, and/or deaths. This study is a multicentre, prospective, randomised study with a cluster group design. The randomisation will be per main nursing home physician and stratified per ward (somatic and psychogeriatric). In the intervention group the clinical decision support system will be used to screen medication list, laboratory values and medical history in order to obtain potential clinical relevant remarks. The remarks will be sent to the main physician and feedback will be provided whether the advice was followed or not. In the control group regular care will be applied. We strongly believe that by using a clinical decision support system, medication reviews are performed in a standardised way which leads to comparable results between patients. In addition, using a clinical decision support system eliminates the time factor to perform medication reviews as the major problems related to medication, laboratory values, indications and/or established patient characteristics will be directly available. In this way, and in order to make the medication review process complete, consultation within healthcare professionals and/or the patient itself will be time effective and the medication surveillance could be performed around the clock. The Netherlands National Trial Register NTR5165 . Registered 2nd April 2015.

  1. Public views on food addiction and obesity: implications for policy and treatment.

    PubMed

    Lee, Natalia M; Lucke, Jayne; Hall, Wayne D; Meurk, Carla; Boyle, Frances M; Carter, Adrian

    2013-01-01

    According to their advocates, neurobiological explanations of overeating, or "food addiction", have the potential to impact public understanding and treatment of obesity. In this study, we examine the public's acceptance of the concept of food addiction as an explanation of overeating and assess its effects upon their attitudes toward obese persons and the treatment of obesity. We conducted an online survey of 479 adults from the US (n = 215) and Australia (n = 264). There was substantial support for the idea of food addiction, particularly among obese participants. Over half favoured treating obesity as a type of addiction. Psychotherapy was believed to be the most effective treatment and educational and support programs were the preferred policies to address food addiction. There was very little support for increasing taxes on obesogenic foods. Despite the strong support for seeing obesity as a form of addiction, respondents still saw obesity as primarily the result of personal choices and emphasized the need for individuals to take responsibility for their eating. Our sample of the general public strongly supported the idea of obesity as a form of food addiction; but this did not translate into support of clinical and public health policies that experts believe are most likely to reduce the prevalence of obesity. The reasons for the apparent disjunction between support for food addiction and a strong emphasis on personal choice for weight warrant further examination.

  2. Principles of strengths-based nursing leadership for strengths-based nursing care: a new paradigm for nursing and healthcare for the 21st century.

    PubMed

    Gottlieb, Laurie N; Gottlieb, Bruce; Shamian, Judith

    2012-06-01

    The current healthcare system is slowly evolving into a new system built on a vision of health promotion, primary care and community-based home care, with hospitals still being a core pillar of the healthcare system but not its primary service. This transformation requires a new approach to practice, namely, Strengths-Based Nursing Care (SBC). SBC is about mobilizing, capitalizing and developing a person's strengths to promote health and facilitate healing. For nurses to practise SBNC requires strong nursing leadership that creates conditions to enable them to do so. Strengths-Based Nursing Leadership complements and acts in synergy with, SBNC. This paper describes eight principles of Strengths-Based Nursing Leadership to support SBNC.

  3. Sensitivity of nonlinear photoionization to resonance substructure in collective excitation

    PubMed Central

    Mazza, T.; Karamatskou, A.; Ilchen, M.; Bakhtiarzadeh, S.; Rafipoor, A. J.; O'Keeffe, P.; Kelly, T. J.; Walsh, N.; Costello, J. T.; Meyer, M.; Santra, R.

    2015-01-01

    Collective behaviour is a characteristic feature in many-body systems, important for developments in fields such as magnetism, superconductivity, photonics and electronics. Recently, there has been increasing interest in the optically nonlinear response of collective excitations. Here we demonstrate how the nonlinear interaction of a many-body system with intense XUV radiation can be used as an effective probe for characterizing otherwise unresolved features of its collective response. Resonant photoionization of atomic xenon was chosen as a case study. The excellent agreement between experiment and theory strongly supports the prediction that two distinct poles underlie the giant dipole resonance. Our results pave the way towards a deeper understanding of collective behaviour in atoms, molecules and solid-state systems using nonlinear spectroscopic techniques enabled by modern short-wavelength light sources. PMID:25854939

  4. High-pressure studies on heavy fermion systems

    NASA Astrophysics Data System (ADS)

    Ye, Chen; Zongfa, Weng; Smidman, Michael; Xin, Lu; Huiqiu, Yuan

    2016-07-01

    In this review article, we give a brief overview of heavy fermions, which are prototype examples of strongly correlated electron systems. We introduce the application of physical pressure in heavy fermion systems to construct their pressure phase diagrams and to study the close relationship between superconductivity (SC) and other electronic instabilities, such as antiferromagnetism (AFM), ferromagnetism (FM), and valence transitions. Field-angle dependent heat capacity and point-contact spectroscopic measurements under pressure are taken as examples to illustrate their ability to investigate novel physical properties of the emergent electronic states. Project supported by the National Basic Research Program of China (Grant No. 2011CBA00103), the National Natural Science Foundation of China (Grant Nos. 11174245 and 11374257), the Science Challenge Program of China, and the Fundamental Research Funds for the Central Universities of China.

  5. A Design of Product Collaborative Online Configuration Model

    NASA Astrophysics Data System (ADS)

    Wang, Xiaoguo; Zheng, Jin; Zeng, Qian

    According to the actual needs of mass customization, the personalization of product and its collaborative design, the paper analyzes and studies the working mechanism of modular-based product configuration technology and puts forward an information model of modular product family. Combined with case-based reasoning techniques (CBR) and the constraint satisfaction problem solving techniques (CSP), we design and study the algorithm for product configuration, and analyze its time complexity. A car chassis is made as the application object, we provide a prototype system of online configuration. Taking advantage of this system, designers can make appropriate changes on the existing programs in accordance with the demand. This will accelerate all aspects of product development and shorten the product cycle. Also the system will provide a strong technical support for enterprises to improve their market competitiveness.

  6. A study of the origin of large magnetic field coupled electric polarization in HoAl(BO3)4

    NASA Astrophysics Data System (ADS)

    Yu, Tian; Zhang, Han; Tyson, Trevor; Chen, Zhiqiang; Abeykoon, Milinda; Nelson, Christie; Bezmaternykh, Leonard

    2015-03-01

    The multiferroic system RAl(BO3)4 is known to exhibit a strong coupling of magnetic field to the electrical polarization. Recently a giant magnetoelectric effect was found in HoAl3(BO3)4 system. This phenomenon is considered quite interesting because the value discovered is significantly higher than reported values of linear magnetoelectric or even multiferroic compounds. We are conducting detailed structural measurements to understand the coupling. We are exploring the local and long range structure in these systems using x-ray PDF, XAFS and single crystal diffraction measurement between 10 K and 400 K. Structural parameters including lattice parameters and ADPs are being determined over the full temperature range. This work is supported by DOE Grant DE-FG02-07ER46402.

  7. Estimating historical groundwater levels based on relations with hydrologic and meteorological variables in the U.S. glacial aquifer system

    NASA Astrophysics Data System (ADS)

    Dudley, R. W.; Hodgkins, G. A.; Nielsen, M. G.; Qi, S. L.

    2018-07-01

    A number of previous studies have examined relations between groundwater levels and hydrologic and meteorological variables over parts of the glacial aquifer system, but systematic analyses across the entire U.S. glacial aquifer system are lacking. We tested correlations between monthly groundwater levels measured at 1043 wells in the U.S. glacial aquifer system considered to be minimally influenced by human disturbance and selected hydrologic and meteorological variables with the goal of extending historical groundwater records where there were strong correlations. Groundwater levels in the East region correlated most strongly with short-term (1 and 3 month) averages of hydrologic and meteorological variables, while those in the Central and West Central regions yielded stronger correlations with hydrologic and meteorological variables averaged over longer time intervals (6-12 months). Variables strongly correlated with high and low annual groundwater levels were identified as candidate records for use in statistical linear models as a means to fill in and extend historical high and low groundwater levels respectively. Overall, 37.4% of study wells meeting data criteria had successful models for high and (or) low groundwater levels; these wells shared characteristics of relatively higher local precipitation, higher local land-surface slope, lower amounts of clay within the surficial sediments, and higher base-flow index. Streamflow and base flow served as explanatory variables in about two thirds of both high- and low-groundwater-level models in all three regions, and generally yielded more and better models compared to precipitation and Palmer Drought Severity Index. The use of variables such as streamflow with substantially longer and more complete records than those of groundwater wells provide a means for placing contemporary groundwater levels in a longer historical context and can support site-specific analyses such as groundwater modeling.

  8. Human Health Effects of Trichloroethylene: Key Findings and Scientific Issues

    PubMed Central

    Jinot, Jennifer; Scott, Cheryl Siegel; Makris, Susan L.; Cooper, Glinda S.; Dzubow, Rebecca C.; Bale, Ambuja S.; Evans, Marina V.; Guyton, Kathryn Z.; Keshava, Nagalakshmi; Lipscomb, John C.; Barone, Stanley; Fox, John F.; Gwinn, Maureen R.; Schaum, John; Caldwell, Jane C.

    2012-01-01

    Background: In support of the Integrated Risk Information System (IRIS), the U.S. Environmental Protection Agency (EPA) completed a toxicological review of trichloroethylene (TCE) in September 2011, which was the result of an effort spanning > 20 years. Objectives: We summarized the key findings and scientific issues regarding the human health effects of TCE in the U.S. EPA’s toxicological review. Methods: In this assessment we synthesized and characterized thousands of epidemiologic, experimental animal, and mechanistic studies, and addressed several key scientific issues through modeling of TCE toxicokinetics, meta-analyses of epidemiologic studies, and analyses of mechanistic data. Discussion: Toxicokinetic modeling aided in characterizing the toxicological role of the complex metabolism and multiple metabolites of TCE. Meta-analyses of the epidemiologic data strongly supported the conclusions that TCE causes kidney cancer in humans and that TCE may also cause liver cancer and non-Hodgkin lymphoma. Mechanistic analyses support a key role for mutagenicity in TCE-induced kidney carcinogenicity. Recent evidence from studies in both humans and experimental animals point to the involvement of TCE exposure in autoimmune disease and hypersensitivity. Recent avian and in vitro mechanistic studies provided biological plausibility that TCE plays a role in developmental cardiac toxicity, the subject of substantial debate due to mixed results from epidemiologic and rodent studies. Conclusions: TCE is carcinogenic to humans by all routes of exposure and poses a potential human health hazard for noncancer toxicity to the central nervous system, kidney, liver, immune system, male reproductive system, and the developing embryo/fetus. PMID:23249866

  9. Operations and support cost modeling using Markov chains

    NASA Technical Reports Server (NTRS)

    Unal, Resit

    1989-01-01

    Systems for future missions will be selected with life cycle costs (LCC) as a primary evaluation criterion. This reflects the current realization that only systems which are considered affordable will be built in the future due to the national budget constaints. Such an environment calls for innovative cost modeling techniques which address all of the phases a space system goes through during its life cycle, namely: design and development, fabrication, operations and support; and retirement. A significant portion of the LCC for reusable systems are generated during the operations and support phase (OS). Typically, OS costs can account for 60 to 80 percent of the total LCC. Clearly, OS costs are wholly determined or at least strongly influenced by decisions made during the design and development phases of the project. As a result OS costs need to be considered and estimated early in the conceptual phase. To be effective, an OS cost estimating model needs to account for actual instead of ideal processes by associating cost elements with probabilities. One approach that may be suitable for OS cost modeling is the use of the Markov Chain Process. Markov chains are an important method of probabilistic analysis for operations research analysts but they are rarely used for life cycle cost analysis. This research effort evaluates the use of Markov Chains in LCC analysis by developing OS cost model for a hypothetical reusable space transportation vehicle (HSTV) and suggests further uses of the Markov Chain process as a design-aid tool.

  10. A plant culture system for producing food and recycling materials with sweetpotato in space

    NASA Astrophysics Data System (ADS)

    Kitaya, Yoshiaki; Yano, Sachiko; Hirai, Hiroaki

    2016-07-01

    The long term human life support in space is greatly dependent on the amounts of food, atmospheric O2 and clean water produced by plants. Therefore, the bio-regenerative life support system such as space farming with scheduling of crop production, obtaining high yields with a rapid turnover rate, converting atmospheric CO2 to O2 and purifying water should be established with employing suitable plant species and varieties and precisely controlling environmental variables around plants grown at a high density in a limited space. We are developing a sweetpotato culture system for producing tuberous roots as a high-calorie food and fresh edible leaves and stems as a nutritive functional vegetable food in space. In this study, we investigated the ability of food production, CO2 to O2 conversion through photosynthesis, and clean water production through transpiration in the sweetpotato production system. The biomass of edible parts in the whole plant was almost 100%. The proportion of the top (leaves and stems) and tuberous roots was strongly affected by environmental variables even when the total biomass production was mostly the same. The production of biomass and clean water was controllable especially by light, atmospheric CO2 and moisture and gas regimes in the root zone. It was confirmed that sweetpotato can be utilized for the vegetable crop as well as the root crop allowing a little waste and is a promising functional crop for supporting long-duration human activity in space.

  11. The North Carolina Coastal Geology Cooperative-a Model of Federal, State, and Academic Cooperation

    NASA Astrophysics Data System (ADS)

    Hoffman, C. W.; Thieler, E. R.; Riggs, S. R.; Schwab, W. C.

    2002-12-01

    In June 1999, The U.S. and N.C. Geological Surveys hosted a meeting of coastal geologists and engineers to identify coastal geological issues of greatest importance to North Carolina and to explore the possibility of initiating a cooperative research program to address these issues. Several factors came together to allow a coordinated program to develop: keen state interest in coastal hazards following several significant hurricanes, interest on the part of the USGS in combining work in North Carolina with a similar program in South Carolina, and recognition of the strong knowledge base that existed within the coastal scientific community in N.C. The meeting resulted in a strong consensus for comprehensive study of the entire coastal system and for initiating work in the northern coastal region (the Quaternary section east of the Suffolk Scarp, focusing on the barrier-island and estuarine system). Among the most important issues to be addressed by the data and knowledge developed from this program are: coastal and estuarine shoreline erosion (controls on erosion rates, sediment transport, response of wetlands to sea level rise); sand resources (location, quality, and quantity of offshore, estuarine, or onshore sand); storm impacts (barrier island/inlet migration, estuarine water movement, relative stability of barrier island segments); sea level change (history and potential impacts); water resources (surface and groundwater); habitat (ability to sustain uses, trends, threats). The cooperative will provide a strong science foundation for management of the N.C. coastal zone. Endorsements, support, and cooperation have come from the N.C. Coastal Resources Commission, several state and federal resource agencies, and local government units who all have an interest in information the program is producing. Supplemental federal appropriations have resulted from such support and the National Park Service has provided partnership funding. Additional partnership opportunities exist and are being pursued with the Army Corps of Engineers (two feasibility studies are active in the project area), the N.C. Outer Banks Task Force, and U.S. Minerals Management Service.

  12. Interagency Collaborative Team Model for Capacity Building to Scale-Up Evidence-Based Practice

    PubMed Central

    Hurlburt, Michael; Aarons, Gregory A; Fettes, Danielle; Willging, Cathleen; Gunderson, Lara; Chaffin, Mark J

    2015-01-01

    Background System-wide scale up of evidence-based practice (EBP) is a complex process. Yet, few strategic approaches exist to support EBP implementation and sustainment across a service system. Building on the Exploration, Preparation, Implementation, and Sustainment (EPIS) implementation framework, we developed and are testing the Interagency Collaborative Team (ICT) process model to implement an evidence-based child neglect intervention (i.e., SafeCare®) within a large children’s service system. The ICT model emphasizes the role of local agency collaborations in creating structural supports for successful implementation. Methods We describe the ICT model and present preliminary qualitative results from use of the implementation model in one large scale EBP implementation. Qualitative interviews were conducted to assess challenges in building system, organization, and home visitor collaboration and capacity to implement the EBP. Data collection and analysis centered on EBP implementation issues, as well as the experiences of home visitors under the ICT model. Results Six notable issues relating to implementation process emerged from participant interviews, including: (a) initial commitment and collaboration among stakeholders, (b) leadership, (c) communication, (d) practice fit with local context, (e) ongoing negotiation and problem solving, and (f) early successes. These issues highlight strengths and areas for development in the ICT model. Conclusions Use of the ICT model led to sustained and widespread use of SafeCare in one large county. Although some aspects of the implementation model may benefit from enhancement, qualitative findings suggest that the ICT process generates strong structural supports for implementation and creates conditions in which tensions between EBP structure and local contextual variations can be resolved in ways that support the expansion and maintenance of an EBP while preserving potential for public health benefit. PMID:27512239

  13. Interagency Collaborative Team Model for Capacity Building to Scale-Up Evidence-Based Practice.

    PubMed

    Hurlburt, Michael; Aarons, Gregory A; Fettes, Danielle; Willging, Cathleen; Gunderson, Lara; Chaffin, Mark J

    2014-04-01

    System-wide scale up of evidence-based practice (EBP) is a complex process. Yet, few strategic approaches exist to support EBP implementation and sustainment across a service system. Building on the Exploration, Preparation, Implementation, and Sustainment (EPIS) implementation framework, we developed and are testing the Interagency Collaborative Team (ICT) process model to implement an evidence-based child neglect intervention (i.e., SafeCare®) within a large children's service system. The ICT model emphasizes the role of local agency collaborations in creating structural supports for successful implementation. We describe the ICT model and present preliminary qualitative results from use of the implementation model in one large scale EBP implementation. Qualitative interviews were conducted to assess challenges in building system, organization, and home visitor collaboration and capacity to implement the EBP. Data collection and analysis centered on EBP implementation issues, as well as the experiences of home visitors under the ICT model. Six notable issues relating to implementation process emerged from participant interviews, including: (a) initial commitment and collaboration among stakeholders, (b) leadership, (c) communication, (d) practice fit with local context, (e) ongoing negotiation and problem solving, and (f) early successes. These issues highlight strengths and areas for development in the ICT model. Use of the ICT model led to sustained and widespread use of SafeCare in one large county. Although some aspects of the implementation model may benefit from enhancement, qualitative findings suggest that the ICT process generates strong structural supports for implementation and creates conditions in which tensions between EBP structure and local contextual variations can be resolved in ways that support the expansion and maintenance of an EBP while preserving potential for public health benefit.

  14. [Post launch studies].

    PubMed

    Akaza, Hideyuki; Ohashi, Yasuo; Shimada, Yasuhiro; Ikeda, Tadashi; Saijo, Nagahiro; Isonishi, Seiji; Hirao, Yoshihiko; Tsuruo, Takashi; Tsukagoshi, Shigeru; Sone, Saburo; Nakamura, Seigo; Kato, Masuhiro; Mikami, Osamu; von Euler, Mikael; Blackledge, George; Milsted, Bob; Vose, Brent

    2002-11-01

    Evidence Based Medicine (EBM) is a growing concept in Japan as it is elsewhere. Central to improving the use of EBM is generation of data through well conducted controlled clinical studies. There are many problems associated with conduct of clinical studies after launch in Japan, and many initiatives are ongoing to improve the situation. Development of Clinical Research Coordinators (CRO) and central Data Management centers are key to improving the quality of clinical research in Japan. Currently Japan has an undeveloped legal system with regard to post-launch trials and off-label use of registered drugs. There is no reimbursement for off-label and various restrictions imposed on the recipients of the Ministry of Health, Labour and Welfare's (MHLW) funds. Maybe the biggest problem is the high cost of post-marketing studies sponsored by pharmaceutical manufacturers. A high quality system to support post launch clinical studies need a solid financial base. There is a need for a suitable review system for investigator initiated multi-centre studies, as the current IRB system is not sufficient. There are also challenges regarding the differences, perceived or real, in treatment practice and available registrations in Japan and in the West, causing problems in choosing suitable comparators and study designs. At the present time it is not clear whether investigator initiated trials will be acceptable for registration purposes in Japan. The agreed first priority is to build a suitable and strong infrastructure within the academic community to support researchers to investigate important questions with or without pharmaceutical company support. Despite all these issues, several groundbreaking projects are under way throughout Japan, in many different areas and by different collaborative groups, some with government support. In fact, researcher-initiated clinical trials achieved a rapid growth in Japan in the past year.

  15. Reversible and strong immobilization of proteins by ionic exchange on supports coated with sulfate-dextran.

    PubMed

    Fuentes, Manuel; Pessela, Benevides C C; Maquiese, Jorgette V; Ortiz, Claudia; Segura, Rosa L; Palomo, Jose M; Abian, Olga; Torres, Rodrigo; Mateo, Cesar; Fernández-Lafuente, Roberto; Guisán, J M

    2004-01-01

    New and strong ionic exchange resins have been prepared by the simple and rapid ionic adsorption of anionic polymers (sulfate-dextran) on porous supports activated with the opposite ionic group (DEAE/MANAE). Ionic exchange properties of such composites were strongly dependent on the size of the ionic polymers as well as on the conditions of the ionic coating of the solids with the ionic polymers (optimal conditions were 400 mg of sulfate-dextran 5000 kDa per gram of support). Around 80% of the proteins contained in crude extracts from Escherichia coli and Acetobacter turbidans could be adsorbed on these porous composites even at pH 7. This interaction was stronger than that using conventional carboxymethyl cellulose (CMC) and even others such as supports coated with aspartic-dextran polymer. By means of the sequential use of the new supports and supports coated with polyethyleneimine (PEI), all proteins from crude extracts could be immobilized. In fact, a large percentage (over 50%) could be immobilized on both supports. Finally, some industrially relevant enzymes (beta-galactosidases from Aspergillus oryzae, Kluyveromyces lactis, and Thermussp. strain T2, lipases from Candida antarctica A and B, Candida rugosa, Rhizomucor miehei, and Rhyzopus oryzae and bovine pancreas trypsin and chymotrypsin) have been immobilized on these supports with very high activity recoveries and immobilization rates. After enzyme inactivation, the protein could be fully desorbed from the support, and then the support could be reused for several cycles. Moreover, in some instances the enzyme stability was significantly improved, mainly in the presence of organic solvents, perhaps as a consequence of the highly hydrophilic microenvironment of the support.

  16. A novel collaborative e-learning platform for medical students - ALERT STUDENT

    PubMed Central

    2014-01-01

    Background The increasing complexity of medical curricula would benefit from adaptive computer supported collaborative learning systems that support study management using instructional design and learning object principles. However, to our knowledge, there are scarce reports regarding applications developed to meet this goal and encompass the complete medical curriculum. The aim of ths study was to develop and assess the usability of an adaptive computer supported collaborative learning system for medical students to manage study sessions. Results A study platform named ALERT STUDENT was built as a free web application. Content chunks are represented as Flashcards that hold knowledge and open ended questions. These can be created in a collaborative fashion. Multiple Flashcards can be combined into custom stacks called Notebooks that can be accessed in study Groups that belong to the user institution. The system provides a Study Mode that features text markers, text notes, timers and color-coded content prioritization based on self-assessment of open ended questions presented in a Quiz Mode. Time spent studying and Perception of knowledge are displayed for each student and peers using charts. Computer supported collaborative learning is achieved by allowing for simultaneous creation of Notebooks and self-assessment questions by many users in a pre-defined Group. Past personal performance data is retrieved when studying new Notebooks containing previously studied Flashcards. Self-report surveys showed that students highly agreed that the system was useful and were willing to use it as a reference tool. Conclusions The platform employs various instructional design and learning object principles in a computer supported collaborative learning platform for medical students that allows for study management. The application broadens student insight over learning results and supports informed decisions based on past learning performance. It serves as a potential educational model for the medical education setting that has gathered strong positive feedback from students at our school. This platform provides a case study on how effective blending of instructional design and learning object principles can be brought together to manage study, and takes an important step towards bringing information management tools to support study decisions and improving learning outcomes. PMID:25017028

  17. A novel collaborative e-learning platform for medical students - ALERT STUDENT.

    PubMed

    Taveira-Gomes, Tiago; Saffarzadeh, Areo; Severo, Milton; Guimarães, M Jorge; Ferreira, Maria Amélia

    2014-07-14

    The increasing complexity of medical curricula would benefit from adaptive computer supported collaborative learning systems that support study management using instructional design and learning object principles. However, to our knowledge, there are scarce reports regarding applications developed to meet this goal and encompass the complete medical curriculum. The aim of ths study was to develop and assess the usability of an adaptive computer supported collaborative learning system for medical students to manage study sessions. A study platform named ALERT STUDENT was built as a free web application. Content chunks are represented as Flashcards that hold knowledge and open ended questions. These can be created in a collaborative fashion. Multiple Flashcards can be combined into custom stacks called Notebooks that can be accessed in study Groups that belong to the user institution. The system provides a Study Mode that features text markers, text notes, timers and color-coded content prioritization based on self-assessment of open ended questions presented in a Quiz Mode. Time spent studying and Perception of knowledge are displayed for each student and peers using charts. Computer supported collaborative learning is achieved by allowing for simultaneous creation of Notebooks and self-assessment questions by many users in a pre-defined Group. Past personal performance data is retrieved when studying new Notebooks containing previously studied Flashcards. Self-report surveys showed that students highly agreed that the system was useful and were willing to use it as a reference tool. The platform employs various instructional design and learning object principles in a computer supported collaborative learning platform for medical students that allows for study management. The application broadens student insight over learning results and supports informed decisions based on past learning performance. It serves as a potential educational model for the medical education setting that has gathered strong positive feedback from students at our school.This platform provides a case study on how effective blending of instructional design and learning object principles can be brought together to manage study, and takes an important step towards bringing information management tools to support study decisions and improving learning outcomes.

  18. Leaving no one behind: lessons on rebuilding health systems in conflict- and crisis-affected states.

    PubMed

    Martineau, Tim; McPake, Barbara; Theobald, Sally; Raven, Joanna; Ensor, Tim; Fustukian, Suzanne; Ssengooba, Freddie; Chirwa, Yotamu; Vong, Sreytouch; Wurie, Haja; Hooton, Nick; Witter, Sophie

    2017-01-01

    Conflict and fragility are increasing in many areas of the world. This context has been referred to as the 'new normal' and affects a billion people. Fragile and conflict-affected states have the worst health indicators and the weakest health systems. This presents a major challenge to achieving universal health coverage. The evidence base for strengthening health systems in these contexts is very weak and hampered by limited research capacity, challenges relating to insecurity and apparent low prioritisation of this area of research by funders. This article reports on findings from a multicountry consortium examining health systems rebuilding post conflict/crisis in Sierra Leone, Zimbabwe, northern Uganda and Cambodia. Across the ReBUILD consortium's interdisciplinary research programme, three cross-cutting themes have emerged through our analytic process: communities, human resources for health and institutions. Understanding the impact of conflict/crisis on the intersecting inequalities faced by households and communities is essential for developing responsive health policies. Health workers demonstrate resilience in conflict/crisis, yet need to be supported post conflict/crisis with appropriate policies related to deployment and incentives that ensure a fair balance across sectors and geographical distribution. Postconflict/crisis contexts are characterised by an influx of multiple players and efforts to support coordination and build strong responsive national and local institutions are critical. The ReBUILD evidence base is starting to fill important knowledge gaps, but further research is needed to support policy makers and practitioners to develop sustainable health systems, without which disadvantaged communities in postconflict and postcrisis contexts will be left behind in efforts to promote universal health coverage.

  19. Advantages of MgAlOx over gamma-Al2O3 as a support material for potassium-based high temperature lean NOx traps

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Luo, Jinyong; Gao, Feng; Karim, Ayman M.

    MgAlOx mixed oxides were employed as supports for potassium-based lean NOx traps (LNTs) targeted for high temperature applications. Effects of support compositions, K/Pt loadings, thermal aging and catalyst regeneration on NOx storage capacity were systematically investigated. The catalysts were characterized by XRD, NOx-TPD, TEM, STEM-HAADF and in-situ XAFS. The results indicate that MgAlOx mixed oxides have significant advantages over conventional gamma-Al2O3-supports for LNT catalysts, in terms of high temperature NOx trapping capacity and thermal stability. First, as a basic support, MgAlOx stabilizes stored nitrates (in the form of KNO3) to much higher temperatures than mildly acidic gamma-Al2O3. Second, MgAlOx minimizesmore » Pt sintering during thermal aging, which is not possible for gamma-Al2O3 supports. Notably, combined XRD, in-situ XAFS and STEM-HAADF results indicate that Pt species in the thermally aged Pt/MgAlOx samples are finely dispersed in the oxide matrix as isolated atoms. This strong metal-support interaction stabilizes Pt and minimizes the extent of sintering. However, such strong interactions result in Pt oxidation via coordination with the support so that NO oxidation activity can be adversely affected after aging which, in turn, decreases NOx trapping ability for these catalysts. Interestingly, a high-temperature reduction treatment regenerates essentially full NOx trapping performance. In fact, regenerated Pt/K/MgAlOx catalyst exhibits much better NOx trapping performance than fresh Pt/K/Al2O3 LNTs over the entire temperature range investigated here. In addition to thermal aging, Pt/K loading effects were systemically studied over the fresh samples. The results indicate that NOx trapping is kinetically limited at low temperatures, while thermodynamically limited at high temperatures. A simple conceptual model was developed to explain the Pt and K loading effects on NOx storage. An optimized K loading, which allows balancing between the stability of nitrates and exposed Pt surface, gives the best NOx trapping capability.« less

  20. Health needs and concerns of male adolescents.

    PubMed

    Pinch, W J; Heck, M; Vinal, D

    1986-01-01

    Lifestyle factors established within the family help determine health-care functioning. Adolescents first may be challenged to meet their own health needs as freshmen in college. A 153-item questionnaire was utilized to examine concerns in the areas of alcohol and other drug use, auto safety, weight and dieting, smoking, sexuality, coping and stress, and selection and utilization of health-care services. One hundred fifty-nine male college students responded. Major problems with alcohol use, auto safety, weight control, stress and sexuality were identified. Positive lifestyle factors that were strongly supported included regular exercise, nonsmoking, regular medical and dental checkups, and the development of some support systems to cope with stress. Health-care services designated by respondents to meet their own needs were significantly different from those services they pointed out as needed for their peers.

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