Sample records for structural features conferring

  1. 2009 Epigenetics Gordon Research Conference (August 9 - 14, 2009)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jeanie Lee

    Epigenetics refers to the study of heritable changes in genome function that occur without a change in primary DNA sequence. The 2009 Gordon Conference in Epigenetics will feature discussion of various epigenetic phenomena, emerging understanding of their underlying mechanisms, and the growing appreciation that human, animal, and plant health all depend on proper epigenetic control. Special emphasis will be placed on genome-environment interactions particularly as they relate to human disease. Towards improving knowledge of molecular mechanisms, the conference will feature international leaders studying the roles of higher order chromatin structure, noncoding RNA, repeat elements, nuclear organization, and morphogenic evolution. Traditionalmore » and new model organisms are selected from plants, fungi, and metazoans.« less

  2. Final report: ES11: The 23rd Annual Workshop on Electronic Structure Methods

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rappe, Andrew M.

    2011-08-31

    ES11: the 23rd Annual Workshop on Electronic Structure Methods was held from June 6-9, 2011 at the University of Pennsylvania. The local organizing committee (see Section II) led by PI Andrew M. Rappe supervised the organization of the conference, before, during, and after the meeting itself. The national organizing committee set the technical program of talks, and provided support and advice in various ways. The conference was well-attended (see Section III). An important feature of this conference was a series of panel discussions (see Section IV) to discuss the field of electronic structure and to set new directions. The technicalmore » program was of extraordinarily high quality (see Section V). The host institution, the University of Pennsylvania, provided a supportive environment for this meeting (see Section VI).« less

  3. ESCOL '90: Proceedings of the Eastern States Conference on Linguistics (7th, Columbus, Ohio, September 21-23, 1990).

    ERIC Educational Resources Information Center

    No, Yongkyoon, Ed.; Libucha, Mark, Ed.

    Papers include: "Length and Structure Effects in Syntactic Processing"; Nantong Tone Sandhi and Tonal Feature Geometry"; "Event Reference and Property Theory"; "Function-Argument Structure, Category Raising and Bracketing Paradoxes"; "At the Phonetics-Phonology Interface: (Re)Syllabification and English Stop…

  4. The Jovian Atmospheres

    NASA Technical Reports Server (NTRS)

    Allison, Michael (Editor); Travis, Larry D. (Editor)

    1986-01-01

    A conference on the atmosphere of Jupiter produced papers in the areas of thermal and ortho-para hydrogen structure, clouds and chemistry, atmospheric structure, global dynamics, synoptic features and processes, atmospheric dynamics, and future spaceflight opportunities. A session on the atmospheres of Uranus and Neptune was included, and the atmosphere of Saturn was discussed in several papers.

  5. Conference on Continental margin mass wasting and Pleistocene sea-level changes, August 13-15, 1980

    USGS Publications Warehouse

    Folger, David W.; Hathaway, J.C.

    1987-01-01

    A conference on Continental Margin Mass Wasting and Pleistocene Sea-Level Changes was held in Woods Hole, Mass., August 13-15, 1980. Forty-seven participants, representing many government, academic, and industrial organizations, discussed the current state of knowledge of the features of marine mass wasting and of the interrelations of factors influencing them. These factors include sediment source, composition, textures, sedimentation rates, climatic and sea-level changes, gas and gas hydrate (clathrate) contents of sediments, geotechnical characteristics, oceanographic and morphological factors, ground-water processes, and seismic events. The part played by these factors in the processes and features of mass movement and the engineering considerations imposed by the emplacement of manmade structures on the sea floor were considered vital to the evaluation of hazards involved in offshore exploration and development. The conference concluded with a call for bold programs to establish the probability of occurrence and the quantitative importance of these factors and to devise more reliable means of measurement, particularly in place, of the characteristics of the sediment and features involved.

  6. AMSAHTS 1990: Advances in Materials Science and Applications of High Temperature Superconductors

    NASA Technical Reports Server (NTRS)

    Bennett, Larry H. (Editor); Flom, Yury (Editor); Moorjani, Kishin (Editor)

    1991-01-01

    This publication is comprised of abstracts for oral and poster presentations scheduled for AMSAHTS '90. The conference focused on understanding high temperature superconductivity with special emphasis on materials issues and applications. AMSAHTS 90, highlighted the state of the art in fundamental understanding of the nature of high-Tc superconductivity (HTSC) as well as the chemistry, structure, properties, processing and stability of HTSC oxides. As a special feature of the conference, space applications of HTSC were discussed by NASA and Navy specialists.

  7. AMSAHTS 1990: Advances in Materials Science and Applications of High Temperature Superconductors

    NASA Technical Reports Server (NTRS)

    Flom, Yury (Editor)

    1990-01-01

    This publication is comprised of abstracts for oral and poster presentations scheduled for AMSAHTS '90. The conference will focus on understanding high-temperature superconductivity with special emphases on materials issues and applications. AMSAHTS '90, will highlight the state of the art in fundamental understanding of the nature of high-Tc superconductivity (HTSC) as well as the chemistry, structure, properties, processing and stability of HTSC oxides. As a special feature of the conference, space applications of HTSC will be discussed by NASA and Navy specialists.

  8. Brainhack: a collaborative workshop for the open neuroscience community.

    PubMed

    Cameron Craddock, R; S Margulies, Daniel; Bellec, Pierre; Nolan Nichols, B; Alcauter, Sarael; A Barrios, Fernando; Burnod, Yves; J Cannistraci, Christopher; Cohen-Adad, Julien; De Leener, Benjamin; Dery, Sebastien; Downar, Jonathan; Dunlop, Katharine; R Franco, Alexandre; Seligman Froehlich, Caroline; J Gerber, Andrew; S Ghosh, Satrajit; J Grabowski, Thomas; Hill, Sean; Sólon Heinsfeld, Anibal; Matthew Hutchison, R; Kundu, Prantik; R Laird, Angela; Liew, Sook-Lei; J Lurie, Daniel; G McLaren, Donald; Meneguzzi, Felipe; Mennes, Maarten; Mesmoudi, Salma; O'Connor, David; H Pasaye, Erick; Peltier, Scott; Poline, Jean-Baptiste; Prasad, Gautam; Fraga Pereira, Ramon; Quirion, Pierre-Olivier; Rokem, Ariel; S Saad, Ziad; Shi, Yonggang; C Strother, Stephen; Toro, Roberto; Q Uddin, Lucina; D Van Horn, John; W Van Meter, John; C Welsh, Robert; Xu, Ting

    2016-01-01

    Brainhack events offer a novel workshop format with participant-generated content that caters to the rapidly growing open neuroscience community. Including components from hackathons and unconferences, as well as parallel educational sessions, Brainhack fosters novel collaborations around the interests of its attendees. Here we provide an overview of its structure, past events, and example projects. Additionally, we outline current innovations such as regional events and post-conference publications. Through introducing Brainhack to the wider neuroscience community, we hope to provide a unique conference format that promotes the features of collaborative, open science.

  9. PREFACE: 15th Russian Youth Conference on Physics and Astronomy (PhysicA.SPb)

    NASA Astrophysics Data System (ADS)

    Sokolovskii, Grigorii; Averkiev, Nikita

    2013-08-01

    The fifteenth Russian Youth Conference on Physics and Astronomy PhysicA.SPb was held 23-24 October 2012 in Saint-Petersburg, Russia. The Conference continues the tradition of Saint-Petersburg Seminars on Physics and Astronomy originating from the mid-90s. The main feature of PhysicA.SPb since then, remains the combination of both scientific and educational quality of the contributions delivered to the young audience. This feature makes it possible to combine the whole spectrum of modern Physics and Astronomy within one conference. PhysicA.SPb 2012 has brought together more than 150 students, young scientists and their professors from many universities and research institutes across Russia, as well as from Belarus, Ukraine, Finland, France and the United Kingdom. Oral and poster presentations were combined into a few well-defined sections among which one should name Astronomy and Astrophysics, Physics of semiconductors, Physics of solid state, Physics and technology of the alternative energetics, Nanostructured and thin-film materials, THz and UHF materials and devices, and Physics of the quantum-sized structures. This issue of the Journal of Physics: Conference Series presents the extended contributions from participants of PhysicA.SPb 2012 that were peer-reviewed by expert referees through processes administered by the Presiders of the Organising and Programme Committees to the best professional and scientific standards. Grigorii S. Sokolovskii and Nikita S. Averkiev Editors

  10. Hedberg Research Conference on Fundamental Controls on Flow in Carbonates: Request for Travel Support for Post-Doctoral Fellows

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pyrak-Nolte, Laura J.

    Carbonate reservoirs pose a scientific and engineering challenge to geophysical prediction and monitoring of fluid flow in the subsurface. Difficulties in interpreting hydrological, reservoir and other exploration data arise because carbonates are composed of a hierarchy of geological structures, constituents and processes that span a wide spectrum of length and time scales. What makes this problem particularly challenging is that length scales associated with physical structure and processes are often not discrete, but overlap, preventing the definition of discrete elements at one scale to become the building blocks of the next scale. This is particularly true for carbonates where complicatedmore » depositional environments, subsequent post-deposition diagenesis and geochemical interactions result in pores that vary in scale from submicron to centimeters to fractures, variation in fabric composition with fossils, minerals and cement, as well as variations in structural features (e.g., oriented inter- and intra layered - interlaced bedding and/or discontinuous rock units). In addition, this complexity is altered by natural and anthropogenic processes such as changes in stress, fluid content, reactive fluid flow, etc. Thus an accurate geophysical assessment of the flow behavior of carbonate reservoirs requires a fundamental understanding of the interplay of textural and structural features subjected to physical processes that affect and occur on various length and time scales. To address this complexity related to carbonates, a Hedberg conference on “Fundamental Controls on Flow in Carbonates” was held July 8 to 13, 2012, to bring together industry and academic scientists to stimulate innovative ideas that can accelerate research advances related to flow prediction and recovery in carbonate reservoirs. Participants included scientist and engineers from multiple disciplines (such as hydrology, structural geology, geochemistry, reservoir engineering, geophysics, geomechanics, numerical modeling, physical experiments, sedimentology, well-testing, statistics, mathematics, visualization, etc.) who encompass experience as well as the latest advances in these multi-faceted fields. One of the goals was to include early career scientists and engineers (post-doctoral fellows, assistant professors, etc.). With this grant 10 early career scientists and engineers were supported to attend the conference. This reports contains a brief overview of the conference and the list of support participants supported by this grant. Full details of the outcomes of the conference are given in the publication found in the Attachment section of this report.« less

  11. Fake/Bogus Conferences: Their Features and Some Subtle Ways to Differentiate Them from Real Ones.

    PubMed

    Asadi, Amin; Rahbar, Nader; Rezvani, Mohammad Javad; Asadi, Fahime

    2018-04-01

    The main objective of the present paper is to introduce some features of fake/bogus conferences and some viable approaches to differentiate them from the real ones. These fake/bogus conferences introduce themselves as international conferences, which are multidisciplinary and indexed in major scientific digital libraries. Furthermore, most of the fake/bogus conference holders offer publishing the accepted papers in ISI journals and use other techniques in their advertisement e-mails.

  12. EDITORIAL: Adaptive and Active Materials: Selected Papers from the ASME 2008 Conference on Smart Materials, Adaptive Structures and Intelligent Systems (SMASIS 08) (Maryland, USA, 28-30 October 2008) Adaptive and Active Materials: Selected Papers from the ASME 2008 Conference on Smart Materials, Adaptive Structures and Intelligent Systems (SMASIS 08) (Maryland, USA, 28-30 October 2008)

    NASA Astrophysics Data System (ADS)

    Lynch, Christopher

    2009-10-01

    The rapid development of the field of Smart Materials, Adaptive Structures, and Materials Systems led the Aerospace Division ASMS TC to launch the new annual SMASIS conference in 2008. The conference focuses on the multi-disciplinary challenges of developing new multifunctional materials and implementing them in advanced systems. The research spans length scales from nano-structured materials to civil, air, and space structures. The first conference consisted of six symposia, each focusing on a different research area. This special issue of Smart Materials and Structures summarizes some of the top research presented at the 2008 SMASIS conference in the materials-focused symposia. These symposia focused on the behavior and mechanics of active materials, on multifunctional materials, and on bio-inspired materials. The behavior and mechanics of active materials is an approach that combines observed material behavior with mechanism-based models that not only give insight into the observed behavior, but guide the development of new materials. This approach has been applied to shape memory metals and polymers, ferroelectrics, ferromagnetics, and recently to multiferroic materials, and has led to considerable improvements in our understanding of multi-field phenomena. Multifunctional materials are the next generation of active materials. These materials include structural, sensing, and actuation components integrated into a material system. A natural extension of multifunctional materials is a new class of bio-inspired materials. Bio-inspired materials range from detailed bio-mimicry of sensing and self healing materials to nano and microstructures that take advantage of features observed in biological systems. The Editors would like to express their sincere thanks to all of the authors for their contributions to this special issue on 'Adaptive and Active Materials' for Smart Materials and Structures. We convey our gratitude to all of the reviewers for their time and dedication. We thank IOP Publishing for their support and encouragement of this special issue and the staff for their special attention and timely response.

  13. Structural design and crashworthiness of automobiles

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Murthy, T.K.S.; Brebbia, C.A.

    1987-01-01

    This book contains contributions on the design of automobile structure, particularly from the viewpoint of its crashworthiness, which is an essential feature for the safety of passengers and other road users. The book provides a work of reference on the design of automobile structures and the papers included are the edited versions of some of the papers presented at the 1st International Conference on Computer Aided Design, Manufacture and Operation in the Automotive Industries (COMPAUTO 87) organized by the Computational Mechanics Institute of Southampton, England.

  14. Featured collection introduction: contaminants of emerging concern II

    USGS Publications Warehouse

    Battaglin, William A.; Kolok, Alan; Battaglin, William; Kolok, Alan

    2014-01-01

    This collection of 13 articles focuses on CECs, and each of the articles highlights a specific aspect of this broad topic. The articles were solicited from researchers who participated in the second summer specialty conference on this topic, organized by the American Water Resources Association. The title of the conference was “CECs in Water Resources II: Research, Engineering and Community Action,” and the conference, as well as the articles in this featured collection, focus on a better and more comprehensive understanding of these contaminants. The conference was held in Denver, Colorado, on June 25-27, 2012, and approximately 125 conference attendees participated in an interdisciplinary forum of more than 75 presentations including keynote or plenary presentations by Dana Kolpin, Jorg Drewes, Heiko Schoenfuss, Chris Metcalfe, Vicki Blazer, and Tyrone Hayes. The first conference was held in 2007 and also produced a featured collection of articles (Battaglin and Kolpin, 2009).

  15. Geologic guide to the island of Hawaii: A field guide for comparative planetary geology

    NASA Technical Reports Server (NTRS)

    Greeley, R. (Editor)

    1974-01-01

    With geological data available for all inner planets except Venus, we are entering an era of true comparative planetary geology, when knowledge of the differences and similarities for classes of structures (e.g., shield volcanoes) will lead to a better understanding of general geological processes, regardless of planet. Thus, it is imperative that planetologists, particularly those involved in geological mapping and surface feature analysis for terrestrial planets, be familiar with volcanic terrain in terms of its origin, structure, and morphology. One means of gaining this experience is through field trips in volcanic terrains - hence, the Planetology Conference in Hawaii. In addition, discussions with volcanologists at the conference provide an important basis for establishing communications between the two fields that will facilitate comparative studies as more data become available.

  16. Determining the Energetics of the Hydrogen Bond through FTIR: A Hands-On Physical Chemistry Lab Experiment

    ERIC Educational Resources Information Center

    Guerin, Abby C.; Riley, Kristi; Rupnik, Kresimir; Kuroda, Daniel G.

    2016-01-01

    Hydrogen bonds are very important chemical structures that are responsible for many unique and important properties of solvents, such as the solvation power of water. These distinctive features are directly related to the stabilization energy conferred by hydrogen bonds to the solvent. Thus, the characterization of hydrogen bond energetics has…

  17. Visualizing bacterial tRNA identity determinants and antideterminants using function logos and inverse function logos

    PubMed Central

    Freyhult, Eva; Moulton, Vincent; Ardell, David H.

    2006-01-01

    Sequence logos are stacked bar graphs that generalize the notion of consensus sequence. They employ entropy statistics very effectively to display variation in a structural alignment of sequences of a common function, while emphasizing its over-represented features. Yet sequence logos cannot display features that distinguish functional subclasses within a structurally related superfamily nor do they display under-represented features. We introduce two extensions to address these needs: function logos and inverse logos. Function logos display subfunctions that are over-represented among sequences carrying a specific feature. Inverse logos generalize both sequence logos and function logos by displaying under-represented, rather than over-represented, features or functions in structural alignments. To make inverse logos, a compositional inverse is applied to the feature or function frequency distributions before logo construction, where a compositional inverse is a mathematical transform that makes common features or functions rare and vice versa. We applied these methods to a database of structurally aligned bacterial tDNAs to create highly condensed, birds-eye views of potentially all so-called identity determinants and antideterminants that confer specific amino acid charging or initiator function on tRNAs in bacteria. We recovered both known and a few potentially novel identity elements. Function logos and inverse logos are useful tools for exploratory bioinformatic analysis of structure–function relationships in sequence families and superfamilies. PMID:16473848

  18. Resilience of Adapting Networks: Results from a Stylized Infrastructure Model.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Beyeler, Walter E.; Vugrin, Eric D.; Forden, Geoffrey Ethan

    2015-01-01

    Adaptation is believed to be a source of resilience in systems. It has been difficult to measure the contribution of adaptation to resilience, unlike other resilience mechanisms such as restoration and recovery. One difficulty comes from treating adaptation as a deus ex machina that is interjected after a disruption. This provides no basis for bounding possible adaptive responses. We can bracket the possible effects of adaptation when we recognize that it occurs continuously, and is in part responsible for the current system’s properties. In this way the dynamics of the system’s pre-disruption structure provides information about post-disruption adaptive reaction. Seenmore » as an ongoing process, adaptation has been argued to produce “robust-yet-fragile” systems. Such systems perform well under historical stresses but become committed to specific features of those stresses in a way that makes them vulnerable to system-level collapse when those features change. In effect adaptation lessens the cost of disruptions within a certain historical range, at the expense of increased cost from disruptions outside that range. Historical adaptive responses leave a signature in the structure of the system. Studies of ecological networks have suggested structural metrics that pick out systemic resilience in the underlying ecosystems. If these metrics are generally reliable indicators of resilience they provide another strategy for gaging adaptive resilience. To progress in understanding how the process of adaptation and the property of resilience interrelate in infrastructure systems, we pose some specific questions: Does adaptation confer resilience?; Does it confer resilience to novel shocks as well, or does it tune the system to fragility?; Can structural features predict resilience to novel shocks?; Are there policies or constraints on the adaptive process that improve resilience?.« less

  19. Comparative analysis of feature extraction methods in satellite imagery

    NASA Astrophysics Data System (ADS)

    Karim, Shahid; Zhang, Ye; Asif, Muhammad Rizwan; Ali, Saad

    2017-10-01

    Feature extraction techniques are extensively being used in satellite imagery and getting impressive attention for remote sensing applications. The state-of-the-art feature extraction methods are appropriate according to the categories and structures of the objects to be detected. Based on distinctive computations of each feature extraction method, different types of images are selected to evaluate the performance of the methods, such as binary robust invariant scalable keypoints (BRISK), scale-invariant feature transform, speeded-up robust features (SURF), features from accelerated segment test (FAST), histogram of oriented gradients, and local binary patterns. Total computational time is calculated to evaluate the speed of each feature extraction method. The extracted features are counted under shadow regions and preprocessed shadow regions to compare the functioning of each method. We have studied the combination of SURF with FAST and BRISK individually and found very promising results with an increased number of features and less computational time. Finally, feature matching is conferred for all methods.

  20. Teaching of Psychology Conference: Ideas & Innovations. Proceedings from the Annual Conference (24th, Tarrytown, NY, March 19-20, 2010)

    ERIC Educational Resources Information Center

    Howell-Carter, Marya, Ed.; Gonder, Jennifer, Ed.

    2010-01-01

    Conference proceedings of the 24th Annual Conference on the Teaching of Psychology: Ideas and Innovations, sponsored by the Psychology Department of the State University of New York at Farmingdale. The conference theme for 2010 was Fostering, Assessing, and Sustaining Student Engagement. The conference featured two keynote addresses from prominent…

  1. 2001 Gordon Research Conference on Archaea: Ecology [sic], Metabolism. Final progress report [agenda and attendee list

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Daniels, Charles

    2001-08-10

    The Gordon Research Conference on Archaea: Ecology, Metabolism [and Molecular Biology] was held at Proctor Academy, Andover, New Hampshire, August 5-10, 2001. The conference was attended by 135 participants. The attendees represented the spectrum of endeavor in this field, coming from academia, industry, and government laboratories, and included US and foreign scientists, senior researchers, young investigators, and students. Emphasis was placed on current unpublished research and discussion of the future target areas in this field. There was a conscious effort to stimulate discussion about the key issues in the field today. Session topics included the following: Ecology and genetic elements;more » Genomics and evolution; Ecology, genomes and gene regulation; Replication and recombination; Chromatin and transcription; Gene regulation; Post-transcription processing; Biochemistry and metabolism; Proteomics and protein structure; Metabolism and physiology. The featured speaker addressed the topic: ''Archaeal viruses, witnesses of prebiotic evolution?''« less

  2. Telling Teacher Talk: Sociolinguistic Features of Writing Conferences.

    ERIC Educational Resources Information Center

    Eodice, Michele

    1998-01-01

    A review of literature in sociolinguistics and classroom conversation reveals areas in which sociolinguistic research and theory can inform the conducting of student writing conferences with teachers. Studies on classroom discourse, communicative competence in classroom exchanges, the nature and role of teacher talk, and the features of…

  3. Designing Online Conferences to Promote Professional Development in Africa

    ERIC Educational Resources Information Center

    Carr, Tony

    2016-01-01

    This article considers how online conferences can support professional development across Africa and reviews elements of the literatures of social learning, online professional development and online conferences. The e/merge online conference is then described in terms of design features and participation metrics. This sets context for discussion…

  4. Linking information and people in a social system for academic conferences

    NASA Astrophysics Data System (ADS)

    Brusilovsky, Peter; Oh, Jung Sun; López, Claudia; Parra, Denis; Jeng, Wei

    2017-04-01

    This paper investigates the feasibility of maintaining a social information system to support attendees at an academic conference. The main challenge of this work was to create an infrastructure where users' social activities, such as bookmarking, tagging, and social linking could be used to enhance user navigation and maximize the users' ability to locate two important types of information in conference settings: presentations to attend and attendees to meet. We developed Conference Navigator 3, a social conference support system that integrates a conference schedule planner with a social linking service. We examined its potential and functions in the context of a medium-scale academic conference. In this paper, we present the design of the system's socially enabled features and report the results of a conference-based study. Our study demonstrates the feasibility of social information systems for supporting academic conferences. Despite the low number of potential users and the short timeframe in which conferences took place, the usage of the system was high enough to provide sufficient data for social mechanisms. The study shows that most critical social features were highly appreciated and used, and provides direction for further research.

  5. Community-partnered research conference model: the experience of Community Partners in Care study.

    PubMed

    Khodyakov, Dmitry; Pulido, Esmeralda; Ramos, Ana; Dixon, Elizabeth

    2014-01-01

    Conducting community-partnered research conferences is a powerful yet underutilized approach to translating research into practice and improving result dissemination and intervention sustainability strategies. Nonetheless, detailed descriptions of conference features and ways to use them in empirical research are rare. We describe how community-partnered conferences may be integrated into research projects by using an example of Community Partners in Care (CPIC), a large, cluster-randomized, controlled, trial (RCT) that uses community-partnered participatory research (CPPR) principles. Our conceptual model illustrates the role community-partnered research conferences may play in three study phases and describes how different conference features may increase community engagement, build two-way capacity, and ensure equal project ownership. As the number of community-partnered studies grows, so too does the need for practical tools to support this work. Community-partnered research conferences may be effectively employed in translational research to increase two-way capacity building and promote long-term intervention success.

  6. Community-Partnered Research Conference Model: The Experience of Community Partners in Care Study

    PubMed Central

    Khodyakov, Dmitry; Pulido, Esmeralda; Ramos, Ana; Dixon, Elizabeth

    2013-01-01

    The Problem Conducting community-partnered research conferences is a powerful yet underutilized approach to translating research into practice and improving result dissemination and intervention sustainability strategies. Nonetheless, detailed descriptions of conference features and ways to use them in empirical research are rare. Purpose of Article We describe how community-partnered conferences may be integrated into research projects by using an example of Community Partners in Care, a large cluster-randomized controlled trial that uses Community Partnered Participatory Research principles. Key Points Our conceptual model illustrates the role community-partnered research conferences may play in three study phases and describes how different conference features may increase community engagement, build two-way capacity, and ensure equal project ownership. Conclusion(s) As the number of community-partnered studies grows, so too does the need for practical tools to support this work. Community-partnered research conferences may be effectively employed in translational research to increase two-way capacity-building and promote long-term intervention success. PMID:24859106

  7. Proceedings of the 28th Annual Farmingdale State College Teaching of Psychology: Ideas and Innovations Conference

    ERIC Educational Resources Information Center

    Howell-Carter, Marya, Ed.; Gonder, Jennifer, Ed.

    2014-01-01

    Proceedings of the 28th Annual Conference on the Teaching of Psychology: Ideas and Innovations, sponsored by the Psychology Department of Farmingdale State College. The conference theme for 2014 was:" Infusing Issues of Racial, Religious, and Sexuality Diversity Across the Undergraduate Curriculum." The Conference featured a keynote…

  8. Special report: FAA's third annual commercial space transportation forecast conference (February 8-9 2000)

    DOT National Transportation Integrated Search

    2000-02-01

    The Third Annual Federal Aviation Administration (FAA) Commercial Space : Transportation Forecast Conference took place in Arlington, Virginia at the Sheraton National Hotel. The year 2000 conference featured seven panels and several special presenta...

  9. PREFACE: 17th Russian Youth Conference on Physics and Astronomy (PhysicA.SPb/2014)

    NASA Astrophysics Data System (ADS)

    Averkiev, Nikita S.; Poniaev, Sergey A.; Sokolovskii, Grigorii S.

    2015-12-01

    The seventeenth Russian Youth Conference on Physics and Astronomy (PhysicA.SPb) was held from 28-30 October 2014 in Saint Petersburg, Russia. The Conference continues the tradition of Saint Petersburg Seminars on Physics and Astronomy originating from the mid-1990s. Since then PhysicA.SPb maintains both the scientific and educational quality of contributions delivered to the young audience. This is the main feature of the Conference that makes it possible to combine the whole spectrum of modern Physics and Astronomy within one event. PhysicA.SPb/2014 has brought together more than 200 students, young scientists and their professor colleagues from many universities and research institutes across the whole of Russia as well as from Belarus, Ukraine, Finland, the Netherlands, France and Germany. Oral and poster presentations were combined into the well-defined sections of Astronomy and Astrophysics, Optics and spectroscopy, Physics of ferroics, Nanostructured and thin-film materials, Mathematical physics and numerical methods, Biophysics, Plasma physics, hydro- and aero-dynamics, and Physics of quantum structures. This volume of Journal of Physics: Conference Series presents the extended contributions from participants of PhysicA.SPb/2014 that were peer-reviewed by expert referees through processes administered by the Presiders of the Organising and Programme Committees to the best professional and scientific standards.

  10. Farmingdale State College Teaching of Psychology: Ideas and Innovations. Proceedings of the Annual Conference (27th, Tarrytown, New York, April 5-6, 2013)

    ERIC Educational Resources Information Center

    Gonder, Jennifer, Ed.; Howell-Carter, Marya, Ed.; Anderson, Jessica, Ed.

    2013-01-01

    Included herein is the conference proceedings of the 27th Annual Conference on the Teaching of Psychology: Ideas and Innovations, sponsored by the Psychology Department of the State University of New York at Farmingdale. The conference theme for 2013 was: The Science of Learning. The Conference featured a keynote address by Victor Benassi, Ph.D.…

  11. Conference report: hot topics in antibody-drug conjugate development.

    PubMed

    Thudium, Karen; Bilic, Sanela

    2013-12-01

    American Association of Pharmaceutical Scientists National Biotechnology Conference Sheraton San Diego Hotel and Marina, San Diego, CA, USA, 19-23 May 2013 The National Biotechnology Conference, is a premier meeting for biotechnology professionals covering a broad range of hot topics in the biotechnology industry. Attracting participants from academia, industry and regulatory, this meeting features sessions that aim to address emerging subjects of interest and allows for open exchange between scientists. The 2013 conference featured leading researchers in the fields of antibody-drug conjugates (ADCs) and immunogenicity. Herein, we present a summary of the ADC hot topics, including bioanalytical and PK considerations, quantitative evaluation of the impact of immunogenicity and ADME to understand ADC drug-drug interactions, and clinical considerations for ADC development. This article aims to summarize the recommendations that were made by the speakers during various sessions throughout the conference.

  12. State-of-the-art of SiAlON materials. [conferences

    NASA Technical Reports Server (NTRS)

    Dutta, S.

    1979-01-01

    Research presented includes work on phase relations, crystal structure, synthesis, fabrication, and properties of various SiAlONs. The essential features of compositions, fabrication methods, and microstructure are reviewed. High temperature flexure strength, creep, fracture toughness, oxidation, and thermal shock resistance are discussed. These data are compared to those for some currently produced silicon nitride ceramics to assess the potential SiAlON materials for use in advanced gas turbine engines.

  13. The Structural Basis for Recognition of the PreQ0 Metabolite by an Unusually Small Riboswitch Aptamer Domain*S⃞♦

    PubMed Central

    Spitale, Robert C.; Torelli, Andrew T.; Krucinska, Jolanta; Bandarian, Vahe; Wedekind, Joseph E.

    2009-01-01

    Riboswitches are RNA elements that control gene expression through metabolite binding. The preQ1 riboswitch exhibits the smallest known ligand-binding domain and is of interest for its economical organization and high affinity interactions with guanine-derived metabolites required to confer tRNA wobbling. Here we present the crystal structure of a preQ1 aptamer domain in complex with its precursor metabolite preQ0. The structure is highly compact with a core that features a stem capped by a well organized decaloop. The metabolite is recognized within a deep pocket via Watson-Crick pairing with C15. Additional hydrogen bonds are made to invariant bases U6 and A29. The ligand-bound state confers continuous helical stacking throughout the core fold, thus providing a platform to promote Watson-Crick base pairing between C9 of the decaloop and the first base of the ribosome-binding site, G33. The structure offers insight into the mode of ribosome-binding site sequestration by a minimal RNA fold stabilized by metabolite binding and has implications for understanding the molecular basis by which bacterial genes are regulated. PMID:19261617

  14. Cystic fibrosis research topics featured at the 14th ECFS Basic Science Conference: Chairman's summary.

    PubMed

    Mall, Marcus A; Hwang, Tzyh-Chang; Braakman, Ineke

    2018-03-01

    In recent years, tremendous progress has been made in the development of novel drugs targeting the basic defect in patients with cystic fibrosis (CF). This breakthrough is based on a solid foundation of knowledge on CFTR's function in health and how mutations in CFTR cause CF multi-organ disease. This knowledge has been collected and continuously expanded by an active and persistent CF research community and has paved the way for precision medicine for CF. Since 2004, the European Cystic Fibrosis Society (ECFS) has held an annual Basic Science Conference that has evolved as an international forum for interdisciplinary discussion of hot topics and unsolved questions related to CF research. This Special Issue reviews CF research topics featured at the 14th ECFS Basic Science Conference and provides an up-to-date overview of recent progress in our understanding of CFTR structure and function, disease mechanisms implicated in airway mucus plugging, inflammation and abnormal host-pathogen interactions, and advancements with enhanced cell and animal model systems and breakthrough therapies directed at mutant CFTR or alternative targets. In addition, this Special Issue also identifies a number of fundamental questions and hurdles that still have to be overcome to realize the full potential of precision medicine and develop transformative therapies for all patients with CF. Copyright © 2017 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.

  15. Crystal Structure of Cockroach Allergen Bla g 2, an Unusual Zinc Binding Aspartic Protease with a Novel Mode of Self-inhibition

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gustchina, Alla; Li, Mi; Wunschmann, Sabina

    2010-07-19

    The crystal structure of Bla g 2 was solved in order to investigate the structural basis for the allergenic properties of this unusual protein. This is the first structure of an aspartic protease in which conserved glycine residues, in two canonical DTG triads, are substituted by different amino acid residues. Another unprecedented feature revealed by the structure is the single phenylalanine residue insertion on the tip of the flap, with the side-chain occupying the S1 binding pocket. This and other important amino acid substitutions in the active site region of Bla g 2 modify the interactions in the vicinity ofmore » the catalytic aspartate residues, increasing the distance between them to {approx}4 {angstrom} and establishing unique direct contacts between the flap and the catalytic residues. We attribute the absence of substantial catalytic activity in Bla g 2 to these unusual features of the active site. Five disulfide bridges and a Zn-binding site confer stability to the protein, which may contribute to sensitization at lower levels of exposure than other allergens.« less

  16. WEST; Report of the Second Annual Conference, February 28-March 2, 1972.

    ERIC Educational Resources Information Center

    Elliott, Richard B., Comp.

    The 1972 WEST conference report represents a cooperative project of the Western Educational Society for Telecommunications and the ERIC Clearinghouse on Media and Technology. The conference featured discussions of public television, instructional television, cable television, national educational radio, and national public radio, educational…

  17. PREFACE: International Conference on Dynamics of Systems on the Nanoscale (DySoN 2012)

    NASA Astrophysics Data System (ADS)

    Solov'yov, Andrey V.

    2013-06-01

    Conference logo The Second International Conference 'Dynamics of Systems on the Nanoscale' (DySoN 2012) took place in Saint Petersburg, Russia between 30 September and 4 October 2012. The venue was the Courtyard by Marriott St Petersburg Vasilievsky Hotel, 2nd line of Vasilievsky Island 61/30A, 199178. The conference was organized by the Frankfurt Institute for Advanced Studies - Goethe University, A F Ioffe Physical-Technical Institute and Saint Petersburg State Polytechnic University. This DySoN conference has been built upon a series of International Symposia 'Atomic Cluster Collisions: structure and dynamics from the nuclear to the biological scale' (ISACC 2003, ISACC 2007, ISACC 2008, ISACC 2009 and ISACC 2011). During these meetings it has become clear that there is a need for an interdisciplinary conference covering a broader range of topics than just atomic cluster collisions, related to the Dynamics of Systems on a Nanoscale. Therefore, in 2010 it was decided to launch a new conference series under the title 'Dynamics of Systems on the Nanoscale'. The first DySoN conference took place at the National Research Council, Rome, Italy in 2010. The DySoN 2012 is the second conference in this series. The DySoN 2012 Conference promoted the growth and exchange of interdisciplinary scientific information on the structure, formation and dynamics of animate and inanimate matter on the nanometer scale. There are many examples of complex many-body systems of micro- and nanometer scale size exhibiting unique features, properties and functions. These systems may have very different nature and origin, e.g. atomic and molecular clusters, nanoobjects, ensembles of nanoparticles, nanostructures, biomolecules, biomolecular and mesoscopic systems. A detailed understanding of the structure and dynamics of these systems on the nanometer scale is an important fundamental task, the solution of which is necessary in numerous applications of nano- and biotechnology, material science and medicine. Although mesoscopic, nano- and biomolecular systems differ in their nature and origin, a number of fundamental problems are common to all of them: what are the underlying principles of self-organization and self-assembly of matter on the micro- and nanoscale? Are these principles classical or quantum? How does function emerge on the nano- and the mesoscale in systems of different origin? What criteria govern the stability of these systems? How do their properties change as a function of size and composition? How are their properties altered by their environment? Seeking answers to these questions is at the core of a new interdisciplinary field that lies at the intersection of physics, chemistry and biology, a field called Meso-Bio-Nano (MBN) Science. Both experimental and theoretical aspects of the mentioned problems were discussed at the DySoN 2012 Conference. Particular attention was devoted to dynamical phenomena and many-body effects taking place in various MBN systems, which include problems of structure formation, fusion and fission, collision and fragmentation, collective electron excitations, reactivity, nanoscale phase transitions, nanoscale insights into biodamage, channeling phenomena and many more. This volume is a collection of the contributions received from the participants of the DySoN 2012 Conference. It provides an overview of the topics, new results and ideas that have been discussed at the conference. I would like to thank all the authors of these proceedings, as well as all the participants of the conference for making it so successful. The third DySoN Conference will be held in Edinburgh in May 2014. A V Solov'yov Frankfurt Institute for Advanced Studies, Ruth-Moufang Str. 1, 60438, Frankfurt am Main, Germany On leave from A F Ioffe Physical-Technical Institute, Polytechnicheskaya 26, 194021, St. Petersburg, Russia E-mail: solovyov@fias.uni-frankfurt.de The PDF contains further information about the conference. Conference photograph Picture

  18. Security and Efficiency Concerns With Distributed Collaborative Networking Environments

    DTIC Science & Technology

    2003-09-01

    have the ability to access Web communications services of the WebEx MediaTone Network from a single login. [24] WebEx provides a range of secure...Web. WebEx services enable secure data, voice and video communications through the browser and are supported by the WebEx MediaTone Network, a global...designed to host large-scale, structured events and conferences, featuring a Q&A Manager that allows multiple moderators to handle questions while

  19. Multilayered silica-biopolymer nanocapsules with a hydrophobic core and a hydrophilic tunable shell thickness

    NASA Astrophysics Data System (ADS)

    Vecchione, Raffaele; Luciani, Giuseppina; Calcagno, Vincenzo; Jakhmola, Anshuman; Silvestri, Brigida; Guarnieri, Daniela; Belli, Valentina; Costantini, Aniello; Netti, Paolo A.

    2016-04-01

    Stable, biocompatible, multifunctional and multicompartment nanocarriers are much needed in the field of nanomedicine. Here, we report a simple, novel strategy to design an engineered nanocarrier system featuring an oil-core/hybrid polymer/silica-shell. Silica shells with a tunable thickness were grown in situ, directly around a highly mono-disperse and stable oil-in-water emulsion system, stabilized by a double bio-functional polyelectrolyte heparin/chitosan layer. Such silica showed a complete degradation in a physiological medium (SBF) in a time frame of three days. Moreover, the outer silica shell was coated with polyethyleneglycol (PEG) in order to confer antifouling properties to the final nanocapsule. The outer silica layer combined its properties (it is an optimal bio-interface for bio-conjugations and for the embedding of hydrophilic drugs in the porous structure) with the capability to stabilize the oil core for the confinement of high payloads of lipophilic tracers (e.g. CdSe quantum dots, Nile Red) and drugs. In addition, polymer layers - besides conferring stability to the emulsion while building the silica shell - can be independently exploited if suitably functionalized, as demonstrated by conjugating chitosan with fluorescein isothiocyanate. Such numerous features in a single nanocarrier system make it very intriguing as a multifunctional platform for smart diagnosis and therapy.Stable, biocompatible, multifunctional and multicompartment nanocarriers are much needed in the field of nanomedicine. Here, we report a simple, novel strategy to design an engineered nanocarrier system featuring an oil-core/hybrid polymer/silica-shell. Silica shells with a tunable thickness were grown in situ, directly around a highly mono-disperse and stable oil-in-water emulsion system, stabilized by a double bio-functional polyelectrolyte heparin/chitosan layer. Such silica showed a complete degradation in a physiological medium (SBF) in a time frame of three days. Moreover, the outer silica shell was coated with polyethyleneglycol (PEG) in order to confer antifouling properties to the final nanocapsule. The outer silica layer combined its properties (it is an optimal bio-interface for bio-conjugations and for the embedding of hydrophilic drugs in the porous structure) with the capability to stabilize the oil core for the confinement of high payloads of lipophilic tracers (e.g. CdSe quantum dots, Nile Red) and drugs. In addition, polymer layers - besides conferring stability to the emulsion while building the silica shell - can be independently exploited if suitably functionalized, as demonstrated by conjugating chitosan with fluorescein isothiocyanate. Such numerous features in a single nanocarrier system make it very intriguing as a multifunctional platform for smart diagnosis and therapy. Electronic supplementary information (ESI) available. See DOI: 10.1039/c6nr01192f

  20. Literary Experience and Literature Teaching since the Growth Model

    ERIC Educational Resources Information Center

    Reid, Ian

    2016-01-01

    By the late 70s the "growth through English" slogan, derived from John Dixon's account of the Dartmouth conference, had become popular around Australia. In 1980 the Sydney IFTE conference featured several Dartmouth veterans; but during that conference, Dartmouth-linked ideas from overseas mingled with lines of local influence, especially…

  1. NDE Conference on Civil Engineering : a joint conference of the 7th Structural Materials Technology Conference (SMT) and the 6th International Symposium on Nondestructive Testing in Civil Engineering (NDT-CE)

    DOT National Transportation Integrated Search

    2007-01-01

    The 2006 NDE conference on Civil Engineering was held in St. Louis, MO on August 14 18, 2006. The conference combined the 7th Structural Materials Technology Conference (SMT) along with the 6th International Symposium on Nondestructive Testing in...

  2. PREFACE: 6th International Conference on Aperiodic Crystals (APERIODIC'09)

    NASA Astrophysics Data System (ADS)

    Grimm, Uwe; McGrath, Rónán; Degtyareva, Olga; Sharma, Hem Raj

    2010-04-01

    Aperiodic Logo Aperiodic'09, the sixth International Conference on Aperiodic Crystals, took place in Liverpool 13-18 September 2009. It was the first major conference in this interdisciplinary research field held in the UK. The conference, which was organised under the auspices of the Commission on Aperiodic Crystals of the International Union of Crystallography (IUCr), followed on from Aperiodic'94 (Les Diablerets, Switzerland), Aperiodic'97 (Alpe d'Huez, France), Aperiodic'2000 (Nijmegen, The Netherlands), Aperiodic'03 (Belo Horizonte, Brazil) and Aperiodic'06 (Zao, Japan). The next conference in the series will take place in Australia in 2012. The Aperiodic conference series is itself the successor to a series of Conferences on Modulated Structures, Polytypes and Quasicrystals (MOSPOQ), which were held in Marseilles (France) in 1984, Wroclaw (Poland) in 1986, Varanasi (India) in 1988 and Balatonszeplak (Hungary) in 1991. The remit of the conference covers two broad areas of research on aperiodic crystals, incommensurately modulated and composite crystals on the one hand, and quasicrystals on the other hand, sharing the property that they are aperiodically ordered solids. In addition, the conference also featured recent research on complex metal alloys, which are in fact periodically ordered solids. However, the term complex refers to their large unit cells, which may contain thousands of atoms, and as a consequence complex metal alloys share some of the properties of quasicrystalline solids. Aperiodic'09 attracted about 110 participants from across the world, including 20 UK-based scientists (the second largest group after Japan who sent 21 delegates). A particular feature of the conference series is its interdisciplinary character, and once again the range of disciplines of participants included mathematics, physics, crystallography and materials science. The programme started with three tutorial lectures on Sunday afternoon, presenting introductory overviews on quasicrystals (Eiji Abe), complex metal alloys (Alessandra Beni) and incommensurately modulated structures (Gervais Chapuis). While these were mainly aimed at younger researchers in the field, the lectures were very well attended and appreciated by the participants. The main programme ran from Monday morning until Friday lunchtime. It comprised 13 invited and 40 contributed plenary talks, and more than 40 posters, which were presented at two afternoon/evening poster sessions. The topics covered in the programme range from mathematical foundations, mathematical models, new materials, sample preparation, structure determination, physical properties and surface properties to industrial applications. Every presenter was invited to submit an article for this proceedings volume, and the 36 peer-reviewed papers in this volume present a cross-section of the range of presentations at the conference. They have been arranged into four categories, (i) quasicrystals, (ii) modulated structures, (iii) mathematical and theoretical aspects of aperiodic order, and (iv) approximants and complex phases. Prizes for best student presentations were awarded to Heinrich Orsini-Rosenberg (ETH Zurich) for his poster Tailor-made sevenfold approximants: ab-initio investigations on formation and stability and to Holger Euchner (Universität Stuttgart) for his contributed talk on Lattice dynamics in complex metallic alloys - vibrational properties of Zn11Mg2. In addition to a cash prize, Heinrich Orsini-Rosenberg received an icosahedral teapot, which was manufactured and donated by David Warrington, and Holger Euchner received a book prize. The meeting started with a welcome reception in the University's recently refurbished Victoria Gallery and Museum. A public lecture Simple sets of shapes that tile the plane but cannot ever repeat by Professor Sir Roger Penrose FRS attracted a wide audience and gave a fascinating insight into the discovery of the Penrose tiling, which is still the paradigm of aperiodic order in two dimensions and used in modelling quasicrystalline materials, some ten years before quasicrystals were first seen in experiment. The conference excursion and dinner centred on the historic waterfront area of this 800-year old city that was designated European Capital of Culture in 2008. The enjoyment of the ferry trip on the Mersey and subsequent walk to the Albert dock museums was greatly enhanced by the fine weather, which lasted throughout the entire conference week. The guests of honour at the conference dinner were Professor Sir Roger Penrose FRS and Professor Alan L Mackay FRS, bringing together two distinguished UK scientists who made seminal contributions to the subject. Besides the scientific programme, the conference also offered a presentation by the author Ann Lingard, whose latest novel The Embalmer's Book of Recipes features a mathematician working on quasicrystals at the University of Liverpool as its main character. A related EPSRC-supported workshop on Mathematical Aspects of Aperiodic Order, organised by Alex Clark, John Hunton and Uwe Grimm, was held in Leicester in the week preceding the conference, and attracted about 40 participants. It is not possible to organise a conference without the help and support of a large number of people, and we would like to take this opportunity to acknowledge the support of everyone who was involved in organising and running this conference. We would like to thank the IUCr Aperiodic Commission, and in particular its chair Professor Marc de Boissieu, who not only entrusted us with hosting the event, but acted as the International Advisory Committee and provided valuable advice and guidance. We are indebted to the members of the International Programme Committee, who helped to put together an exciting programme by suggesting invited speakers and selecting presentations for contributed plenary talks. We are immensely grateful to all members of the National Organising Committee, who provided essential support during the organising stage and during the conference itself, and we would particularly like to thank the conference secretary, Mrs Angie Reid, for her excellent administrative support before, during and after the conference, and for her help in the production of this volume. We are very much indebted to out co-editors, Dr Olga Degtyareva (Edinburgh) and Dr Hem Raj Sharma (Liverpool), for their contributions to the editing of this volume. Finally, and most of all, we would like to thank all participants of the conference for coming to Liverpool, for contributing by presenting their recent work and taking part in discussions, and for creating such an enjoyable and fruitful collegiate atmosphere throughout the week. Last but not least we would like to express our gratitude for the generous financial support we received from the Open University, the University of Liverpool and the Institute of Physics (Mathematical and Theoretical Physics Group and Thin Films and Surfaces Group). The International Union of Crystallography provided financial sponsorship which was allocated to support the participation of 15 young scientists. The European Network of Excellence on Complex Metallic Alloys provided travel and subsistence support to members of participating organisations. Rónán McGrath Uwe Grimm Conference photograph

  3. Morphological optimization for access to dual oxidants in biofilms

    PubMed Central

    Kempes, Christopher P.; Okegbe, Chinweike; Mears-Clarke, Zwoisaint; Follows, Michael J.; Dietrich, Lars E. P.

    2014-01-01

    A major theme driving research in biology is the relationship between form and function. In particular, a longstanding goal has been to understand how the evolution of multicellularity conferred fitness advantages. Here we show that biofilms of the bacterium Pseudomonas aeruginosa produce structures that maximize cellular reproduction. Specifically, we develop a mathematical model of resource availability and metabolic response within colony features. This analysis accurately predicts the measured distribution of two types of electron acceptors: oxygen, which is available from the atmosphere, and phenazines, redox-active antibiotics produced by the bacterium. Using this model, we demonstrate that the geometry of colony structures is optimal with respect to growth efficiency. Because our model is based on resource dynamics, we also can anticipate shifts in feature geometry based on changes to the availability of electron acceptors, including variations in the external availability of oxygen and genetic manipulation that renders the cells incapable of phenazine production. PMID:24335705

  4. Teaching of Psychology: Ideas and Innovations. Proceedings of the Annual Conference on Undergraduate Teaching of Psychology (19th, Monticello, New York, April 6-8, 2005)

    ERIC Educational Resources Information Center

    Zaromatidis, Katherine, Ed.; Oswald, Patricia A., Ed.; Levine, Judith R., Ed.; Indenbaum, Gene, Ed.

    2005-01-01

    The 19th Annual Conference on Undergraduate Teaching of Psychology was held on April 6-8, 2005 at Kutsher's Country Club in Monticello, New York. The conference was sponsored by the Psychology Department of the State University of New York at Farmingdale. The conference featured two keynote speakers--Dr. James Naire, sponsored by Wadsworth…

  5. Characterization and Comparison of the Structural Features, Immune-Modulatory and Anti-Avian Influenza Virus Activities Conferred by Three Algal Sulfated Polysaccharides

    PubMed Central

    Song, Lin; Chen, Xiaolin; Liu, Xiaodong; Zhang, Fubo; Hu, Linfeng; Yue, Yang; Li, Kecheng; Li, Pengcheng

    2015-01-01

    Three marine macroalgae, i.e., Grateloupia filicina, Ulva pertusa and Sargassum qingdaoense, were selected as the deputies of Rhodophyta, Chlorophyta and Ochrophyta for comparative analysis of the molecular structures and biological activities of sulfated polysaccharides (SP). The ratio of water-soluble polysaccharides, the monosaccharide composition and the sulfated contents of three extracted SPs were determined, and their structures were characterized by Fourier transformation infrared spectroscopy. In addition, biological activity analysis showed that all three SPs had immune-modulatory activity both in vitro and in vivo, and SPs from S. qingdaoense had the best effect. Further bioassays showed that three SPs could not only enhance the immunity level stimulated by inactivated avian influenza virus (AIV) in vivo but also significantly inhibited the activity of activated AIV (H9N2 subtype) in vitro. G. filicina SP exhibited the strongest anti-AIV activity. These results revealed the variations in structural features and bioactivities among three SPs and indicated the potential adjuvants for immune-enhancement and anti-AIV. PMID:26729137

  6. Rhetoric in Competition: The Formation of Organizational Discourse in Conference on College Composition and Communication Abstracts.

    ERIC Educational Resources Information Center

    Faber, Brenton

    1996-01-01

    Explores features of conference proposals submitted to the Conference on College Composition in 1989, 1990, and 1992--345 abstracts in total. Results showed that successful abstracts were more likely to follow generic qualities associated with "unsolicited proposals"; foundational discourse remained constant throughout the abstracts but…

  7. NASA/DOD Control/Structures Interaction Technology, 1986

    NASA Technical Reports Server (NTRS)

    Wright, Robert L. (Compiler)

    1987-01-01

    Papers presented at the CSI Technology Conference are given. The conference was jointly sponsored by the NASA Office of Aeronautics and Space Technology and the Department of Defense. The conference is the beginning of a series of annual conferences whose purpose is to report to industry, academia, and government agencies the current status of Control/Structures Interaction technology. The conference program was divided into five sessions: (1) Future spacecraft requirements; Technology issues and impact; (2) DOD special topics; (3) Large space systems technology; (4) Control of flexible structures, and (5) Selected NASA research in control structures interaction.

  8. XVII International Conference on Hadron Spectroscopy and Structure

    NASA Astrophysics Data System (ADS)

    2017-09-01

    The Hadron 2017 Conference is the seventeenth of a series of biennial conferences started in 1985 at Maryland, USA. Its official name, XVII International Conference on Hadron Spectroscopy and Structure, includes for the first time the term structure to emphasize the importance that this issue has acquired in recent editions of the series. The aim of the conference is to provide an overview of the present status and progress in hadron structure and dynamics, as well as a preview of the forthcoming investigations. It will cover lectures on both experimental and theoretical aspects, including in particular the presentation of new results.

  9. CROI 2018: Advances in Basic Science Understanding of HIV.

    PubMed

    Stevenson, Mario

    2018-05-01

    The conference on Retroviruses and Opportunistic Infections represents the most important venue for the dissemination of research advances in HIV and AIDS. The 25th conference, held in Boston, featured presentations that provided insight into the mechanisms of HIV-1 spread in tissues as well as new information on mechanisms of HIV-1 persistence in individuals on effective antiretroviral treatment. The ability of the conference to convey research findings for a general audience is enhanced, to a large part, by preconference workshops. These workshops feature leading researchers who aim to present cutting edge research to a general audience. These sessions rank highly in terms of education and professional value.

  10. A bioinformatics potpourri.

    PubMed

    Schönbach, Christian; Li, Jinyan; Ma, Lan; Horton, Paul; Sjaugi, Muhammad Farhan; Ranganathan, Shoba

    2018-01-19

    The 16th International Conference on Bioinformatics (InCoB) was held at Tsinghua University, Shenzhen from September 20 to 22, 2017. The annual conference of the Asia-Pacific Bioinformatics Network featured six keynotes, two invited talks, a panel discussion on big data driven bioinformatics and precision medicine, and 66 oral presentations of accepted research articles or posters. Fifty-seven articles comprising a topic assortment of algorithms, biomolecular networks, cancer and disease informatics, drug-target interactions and drug efficacy, gene regulation and expression, imaging, immunoinformatics, metagenomics, next generation sequencing for genomics and transcriptomics, ontologies, post-translational modification, and structural bioinformatics are the subject of this editorial for the InCoB2017 supplement issues in BMC Genomics, BMC Bioinformatics, BMC Systems Biology and BMC Medical Genomics. New Delhi will be the location of InCoB2018, scheduled for September 26-28, 2018.

  11. Teaching of Psychology: Ideas and Innovations. Proceedings of the Annual Conference on Undergraduate Teaching of Psychology (23rd, Tarrytown, New York, March 20-21, 2009)

    ERIC Educational Resources Information Center

    Howell-Carter, Marya, Ed.; Gonder, Jennifer, Ed.

    2009-01-01

    The document is a summary of the conference proceedings for the 23rd Annual Farmingdale State College Teaching of Psychology Conference held on March 20-21, 2009 at the DoubleTree Hotel in Tarrytown, New York. The conference featured a keynote address by Dr. Jeffrey Nevid on Reaching and teaching the millennials: Helping today's students become…

  12. The Federal Forecasters Conference--2000. Papers and Proceedings (11th, Washington, DC, September 14, 2000).

    ERIC Educational Resources Information Center

    Gerald, Debra, E., Ed.

    The 11th Federal Forecasters Conference provided a forum where 180 forecasters from different federal agencies and other organizations could meet and discuss forecasting in the United States. The theme for this conference was "Forecasting, Policy, and the Internet." In the morning session, a panel presentation featured three speakers. Neilson C.…

  13. FOREWORD: Structural Health Monitoring and Intelligent Infrastructure

    NASA Astrophysics Data System (ADS)

    Wu, Zhishen; Fujino, Yozo

    2005-06-01

    This special issue collects together 19 papers that were originally presented at the First International Conference on Structural Health Monitoring and Intelligent Infrastructure (SHMII-1'2003), held in Tokyo, Japan, on 13-15 November 2003. This conference was organized by the Japan Society of Civil Engineers (JSCE) with partial financial support from the Japan Society for the Promotion of Science (JSPS) and the Ministry of Education, Culture, Sport, Science and Technology, Japan. Many related organizations supported the conference. A total of 16 keynote papers including six state-of-the-art reports from different counties, six invited papers and 154 contributed papers were presented at the conference. The conference was attended by a diverse group of about 300 people from a variety of disciplines in academia, industry and government from all over the world. Structural health monitoring (SHM) and intelligent materials, structures and systems have been the subject of intense research and development in the last two decades and, in recent years, an increasing range of applications in infrastructure have been discovered both for existing structures and for new constructions. SHMII-1'2003 addressed progress in the development of building, transportation, marine, underground and energy-generating structures, and other civilian infrastructures that are periodically, continuously and/or actively monitored where there is a need to optimize their performance. In order to focus the current needs on SHM and intelligent technologies, the conference theme was set as 'Structures/Infrastructures Sustainability'. We are pleased to have the privilege to edit this special issue on SHM and intelligent infrastructure based on SHMII-1'2003. We invited some of the presenters to submit a revised/extended version of their paper that was included in the SHMII-1'2003 proceedings for possible publication in the special issue. Each paper included in this special issue was edited with the same quality standards as for any paper in a regular issue. The papers cover a wide spectrum of topics including smart and effective sensing technologies, reliable approaches to signal processing, rational data gathering and interpretation methods, advanced damage characterization, modeling feature selection and diagnosis methods, and system integration technologies, etc. This special issue contains the most up-to-date achievements in SHM and intelligent technologies and provides information pertaining to their current and potential applications in infrastructure. It is our hope that this special issue makes a significant contribution in advancing awareness and acceptance of SHM and intelligent technologies for the maintenance and construction of different kinds of infrastructure. We would like to express our sincere thanks to Professor Varadan (Editor-in-Chief), Professor Matsuzaki (Regional Editor), the Editorial Assistants and the staff at Institute of Physics Publishing for their great support and advice in publishing this special issue. Special thanks are due to all the reviewers for their willingness to share their time and expertise. Final but important thanks go to Ms Suzhen Li (Doctorate Candidate at Ibaraki University) for her assistance in editing this special issue.

  14. Teaching of Psychology: Ideas and Innovations. Proceedings and Papers of the Annual Conference on Undergraduate Teaching of Psychology (22nd, White Plains, New York, March 7-8, 2008)

    ERIC Educational Resources Information Center

    Oswald, Patricia A., Ed.; Zaromatidis, Katherine, Ed.; Levine, Judith R., Ed.; Indenbaum, Gene, Ed.

    2008-01-01

    The ND Annual Conference--Teaching of Psychology: Ideas and Innovations was held on March 7-8, 2008 at the Crowne Plaza in White Plains, New York. The conference was sponsored by the Psychology Department of Farmingdale State College. The conference featured Dr. Douglas Bernstein from the University of South Florida, Tampa as the keynote speaker.…

  15. CILT2000: Views of CILT2000.

    ERIC Educational Resources Information Center

    Collins, Allan

    2002-01-01

    Features comments on the Center for Innovative Learning Technologies (CILT) conference held in 2000 and addresses the five thematic areas around which the conference was organized, namely assessment, professional development, visualization and modeling, ubiquitous computing, and equity. (Author/YDS)

  16. National Conference on Wood Transportation Structures

    Treesearch

    Michael A. Ritter; Sheila Rimal Duwadi; Paula D. Hilbrich Lee

    1996-01-01

    The Federal Highway Administration and the USDA Forest Service, Forest Products Laboratory, jointly sponsored the National Conference on Wood Transportation Structures, October 23-25, 1996, in Madison, Wisconsin. This was a direct result of 5 years of cooperation in conducting research related to timber transportation structures. The objective of the conference was to...

  17. A Report on the Peace Education Commission Program, International Peace Research Association Conference 2010, Sydney, Australia

    ERIC Educational Resources Information Center

    Toh, Swee-Hin

    2010-01-01

    From July 6th to 10th, 2010, International Peace Research Association (IPRA) held its biennial conference at the University of Sydney in Australia. Hosted by the University's Centre for Peace & Conflict Studies and coordinated by Jake Lynch and a team of dedicated staff and volunteers, the conference featured seven plenary panels and many…

  18. Semi-annual conference review January-June 2000

    Treesearch

    John K. Borchardt; Marguerite S. Sykes; Mahendra R. Doshi

    2000-01-01

    Conferences covered in this semiannual review include the TAPPI Recycling Symposium and the 9th PTS/CTP Deinking Symposium. The intent of this feature is to present a synopsis of the significant research results and industry ideas related to paper recycling reported at these conferences. Due to space constraints, we are not able to cover all of the presented papers in...

  19. PREFACE: 16th Russian Youth Conference on Physics and Astronomy (PhysicA.SPb/2013)

    NASA Astrophysics Data System (ADS)

    2014-12-01

    The sixteenth Russian Conference on Physics and Astronomy PhysicA.SPb was held 23-24 October 2013 in Saint-Petersburg, Russia. The Conference continues the tradition of Saint-Petersburg Seminars on Physics and Astronomy originating from mid-90s. Since then PhysicA.SPb maintains both scientific and educational quality of contributions delivered to the young audience. This is the main feature of the Conference that makes it possible to combine the whole spectrum of modern Physics and Astronomy within one event. PhysicA.SPb/2013 has brought together about 200 students, young scientists and their colleague professors from many universities and research institutes across whole Russia as well as from Belarus, Ukraine, Switzerland, Turkey, Finland and France. Oral and poster presentations were combined into a few well-defined sections among which one should name Astronomy and Astrophysics, Plasma physics, hydro- and aero-dynamics, Physics of quantum-sized structures, Nanostructured and thin-film materials, Biophysics, THz and UHF materials and devices, Optoelectronic devices, Optics and spectroscopy, Atomic and elementary particles physics, Defects and impurities in solid state, Physics and technology of the alternative energetics. This issue of the Journal of Physics: Conference Series presents the extended contributions from participants of PhysicA.SPb/2013 that were peer-reviewed by expert referees through processes administered by the Presiders of the Organising and Programme Committees to the best professional and scientific standards. The Editors: Nikita S. Averkiev, Sergey A. Poniaev and Grigorii S. Sokolovskii

  20. Highlights from the 24th Conference on Retroviruses and Opportunistic Infections: 13-16 February 2017, Seattle, Washington, USA.

    PubMed

    Crowell, Trevor A; Lyall, Hermione; Malatinkova, Eva; Bhagani, Sanjay; Hsu, Denise; Colby, Donn J; Polyak, Christina; Psomas, Christina; Hill, Andrew; Gathogo, Esther N; Trypsteen, Wim; Vandekerckhove, Linos; Kinloch, Sabine

    2017-04-01

    From the 13th to 16th February 2017, researchers from around the world convened for the 24th annual Conference on Retroviruses and Opportunistic Infections (CROI) at the Washington State Convention Center in Seattle, Washington. The conference was organised by the International Antiviral Society-USA (IAS-USA) in partnership with the CROI Foundation. The conference included over 1000 oral and poster presentations of peer-reviewed original research as well as lectures and symposia featuring insights from leading basic, translational and clinical researchers. Highlighted here are key data presented at the conference.

  1. Effective ways to communicate research using the poster format

    USDA-ARS?s Scientific Manuscript database

    Numerous academic conferences feature multiple venues for presentation of academic research results. While numerous associations provide conference presenters with potential best practices for the generation and presentation of information, not all presenters follow the suggested guidelines. This st...

  2. The Third International Conference: Tokyo

    ERIC Educational Resources Information Center

    Kidd, J. Roby

    1972-01-01

    The Tokyo Conference featured more of an acceptance of established theory, agreement on broad programs, and consolidation of approaches. It also made clear the fact that governments now take, and expect to take a much greater responsibility for adult education. (Author/RK)

  3. Adaptive and active materials: selected papers from the ASME 2012 Conference on Smart Materials, Adaptive Structures and Intelligent Systems (SMASIS 12) (Stone Mountain, GA, USA, 19-21 September 2012)

    NASA Astrophysics Data System (ADS)

    Seelecke, Stefan; Erturk, Alper; Ounaies, Zoubeida; Naguib, Hani; Huber, John; Turner, Travis; Anderson, Iain; Philen, Michael; Baba Sundaresan, Vishnu

    2013-09-01

    The fifth annual meeting of the ASME/AIAA Smart Materials, Adaptive Structures and Intelligent Systems Conference (SMASIS) was held in beautiful Stone Mountain near Atlanta, GA. It is the conference's objective to provide an up-to-date overview of research trends in the entire field of smart materials systems. This was reflected in keynote speeches by Professor Eduard Arzt (Institute of New Materials and Saarland University, Saarbrücken, Germany) on 'Micro-patterned artificial 'Gecko' surfaces: a path to switchable adhesive function', by Professor Ray H Baughman (The Alan G MacDiarmid NanoTech Institute, University of Texas at Dallas) on 'The diverse and growing family of carbon nanotube and related artificial muscles', and by Professor Richard James (University of Minnesota) on 'The direct conversion of heat to electricity using multiferroic materials with phase transformations'. SMASIS 2012 was divided into eight symposia which span basic research, applied technological design and development, and industrial and governmental integrated system and application demonstrations. • SYMP 1. Development and characterization of multifunctional materials. • SYMP 2. Mechanics and behavior of active materials. • SYMP 3. Modeling, simulation and control of adaptive systems. • SYMP 4. Integrated system design and implementation. • SYMP 5. Structural health monitoring/NDE. • SYMP 6. Bio-inspired materials and systems. • SYMP 7. Energy harvesting. • SYMP 8. Structural and materials logic. This year we were particularly excited to introduce a new symposium on energy harvesting, which has quickly matured from a special track in previous years to an independent symposium for the first time. The subject cuts across fields by studying different materials, ranging from piezoelectrics to electroactive polymers, as well as by emphasizing different energy sources from wind to waves and ambient vibrations. Modeling, experimental studies, and technology applications all belong to the symposium topics. In addition, the conference also featured a special symposium dedicated to DARPA's structural and materials/logic program. The program seeks to enable structural systems to adapt to varying loads and simultaneously exhibit both high stiffness and high damping. Authors of selected papers in the materials areas (symposia 1, 2, and 6) as well as energy harvesting (symposium 7) were invited to write a full journal article on their presentation topic for publication in this special issue of Smart Materials and Structures . This collection of papers demonstrates the exceptional quality and originality of the conference presentations. We are very appreciative of their efforts to produce this collection of highly relevant articles on smart materials.

  4. Synthesis, activity and pharmacophore development for isatin-β-thiosemicarbazones with selective activity towards multidrug resistant cellsa

    PubMed Central

    Hall, Matthew D.; Salam, Noeris K.; Hellawell, Jennifer L.; Fales, Henry M.; Kensler, Caroline B.; Ludwig, Joseph A.; Szakacs, Gergely; Hibbs, David E.; Gottesman, Michael M.

    2009-01-01

    We have recently identified a new class of compounds that selectively kill cells that express P-glycoprotein (P-gp, MDR1), the ATPase efflux pump that confers multidrug resistance on cancer cells. Several isatin-β-thiosemicarbazones from our initial study have been validated, and a range of analogs synthesized and tested. A number demonstrated improved MDR1-selective activity over the lead, NSC73306 (1). Pharmacophores for cytotoxicity and MDR1-selectivity were generated to delineate the structural features required for activity. The MDR1-selective pharmacophore highlights the importance of aromatic/hydrophobic features at the N4 position of the thiosemicarbazone, and the reliance on the isatin moiety as key bioisosteric contributors. Additionally, a quantitative structure-activity relationship (QSAR) model that yielded a cross-validated correlation coefficient of 0.85 effectively predicts the cytotoxicty of untested thiosemicarbazones. Together, the models serve as effective approaches for predicting structures with MDR1-selective activity, and aid in directing the search for the mechanism of action of 1. PMID:19397322

  5. Iridescence: views from many angles.

    PubMed

    Meadows, Melissa G; Butler, Michael W; Morehouse, Nathan I; Taylor, Lisa A; Toomey, Matthew B; McGraw, Kevin J; Rutowski, Ronald L

    2009-04-06

    Iridescent colours have been fascinating to humans throughout history; they are flashy, shimmering, dynamic, and examples surround us, from the commonly seen iridescent sheen of oily street puddles to the exotic, gaudy displays of birds-of-paradise featured in nature documentaries. Iridescent colours and the structures that produce them have unique properties in comparison with other types of colourants found in nature. Scientists from a variety of disciplines study the optics, development, heritability, chemical make-up, origin, evolution, functions and biomimetic technological applications of naturally occurring iridescent colours. For the first time, graduate students at Arizona State University brought together these scientists, along with educators and artists, at 'Iridescence: more than meets the eye', a conference to promote interdisciplinary communication and collaboration in the study of iridescent coloration from all of these perspectives. Here, we summarize the outcomes of this conference, introduce the papers that follow in this special journal issue and briefly review the current status of our understanding of iridescence.

  6. The beginning of Francoist psychiatry: the National Neurology and Psychiatry Conference (Barcelona, 1942).

    PubMed

    Huertas, Rafael

    While there has been some research into Francoist psychiatry, much work still needs to be done on the reorganization of the mental health profession within the new state. Held in Barcelona on 12, 13 and 14th January 1942, the National Neurology and Psychiatry Conference undoubtedly played a major role in the attempt to overthrow the dominant ideas in the field of Spanish psychiatry and displace its most influential figures. This article seeks to analyse the Conference's main organizational features and examine its most significant content, with the aim of evaluating its strategic importance in the context of both the psychiatrists' professional and scientific interests and their ideological and political concerns. Conference papers tackled issues such as neurology and psychiatry in wartime, vitamin deficiency and the nervous system, and new psychiatric treatments, including shock therapy. The Conference's marked ideological nature represented the beginning of a new professional dynamic, featuring the emergence or establishment of new leaders intent on laying the foundations of psychiatry during the early years of the Franco regime.

  7. 2011 Photosynthesis Gordon Research Conference & Seminar (June 11-17, 2011, Davidson College, Davidson, North Carolina)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Prof. Krishna Niyogi

    2011-06-17

    Photosynthesis is the biological process that converts solar energy into chemical energy. Elucidation of the mechanisms of photosynthetic energy conversion at a molecular level is fundamentally important for understanding the biology of photosynthetic organisms, for optimizing biological solar fuels production, and for developing biologically inspired approaches to solar energy conversion. The 2011 Gordon Conference on Photosynthesis will present cutting-edge research focusing on the biochemical aspects of photosynthesis, including: (1) structure, assembly, and function of photosynthetic complexes; (2) the mechanism of water splitting by PSII; (3) light harvesting and quenching; (4) alternative electron transport pathways; (5) biosynthesis of pigments and cofactors;more » and (6) improvement of photosynthesis for bioenergy and food production. Reflecting the interdisciplinary nature of photosynthesis research, a diverse group of invited speakers will represent a variety of scientific approaches to investigate photosynthesis, such as biochemistry, molecular genetics, structural biology, systems biology, and spectroscopy. Highly interactive poster sessions provide opportunities for graduate students and postdocs to present their work and exchange ideas with leaders in the field. One of the highlights of the Conference is a session featuring short talks by junior investigators selected from the poster presentations. The collegial atmosphere of the Photosynthesis GRC, with programmed discussion sessions as well as informal gatherings in the afternoons and evenings, enables participants to brainstorm, exchange ideas, and forge new collaborations. For the second time, this Conference will be immediately preceded by a Gordon Research Seminar on Photosynthesis (June 11-12, 2011, at the same location), with a focus on 'Photosynthesis, Bioenergy, and the Environment.' The GRS provides an additional opportunity for graduate students and postdocs to present their research, and it provides a mechanism to encourage active participation by junior scientists interested in photosynthesis and its applications.« less

  8. Investing in Our Human Capital. Highlights of the National Alliance of Business Annual Conference (Washington, D.C., September 29-October 1, 1997).

    ERIC Educational Resources Information Center

    Mower, Eleanor

    In September 1997, more than 900 corporate leaders, educators, work force development professionals, coalition members, employment and training specialists and government officials participated in a conference focused on the new realities in the work force and workplace. The conference featured papers on such topics as the implications of a global…

  9. Report on the National Conference for Youth on Drinking and Driving (Washington, D.C., April 27-30, 1984).

    ERIC Educational Resources Information Center

    Birch & Davis Associates, Inc., Silver Spring, MD.

    This report on the second National Conference for Youth on Drinking and Driving focuses on the potential of the workplace as a site for the prevention of teenage alcohol abuse, with a special emphasis on drinking and driving. Features of the conference are described which may be of interest to employers of youth, youth specialists, and alcohol…

  10. Proceedings of the Conference of the International Group for the Psychology of Mathematics Education (30th, Prague, Czech Republic, July 16-21, 2006). Volume 4

    ERIC Educational Resources Information Center

    Novotna, Jarmila, Ed.; Moraova, Hana, Ed.; Kratka, Magdalena, Ed.; Stehlikova, Nad'a, Ed.

    2006-01-01

    This document contains the fourth volume of the proceedings of the 30th Conference of the International Group for the Psychology of Mathematics Education. Conference presentations are centered around the theme "Mathematics at the Centre." This volume features 59 research reports by presenters with last names beginning between Kun and…

  11. Proceedings of the Conference of the International Group for the Psychology of Mathematics Education (30th, Prague, Czech Republic, July 16-21, 2006). Volume 2

    ERIC Educational Resources Information Center

    Novotna, Jarmila, Ed.; Moraova, Hana, Ed.; Kratka, Magdalena, Ed.; Stehlikova, Nad'a, Ed.

    2006-01-01

    This document contains the second volume of the proceedings of the 30th Annual Conference of the International Group for the Psychology of Mathematics Education. Conference presentations are centered around the theme "Mathematics at the Centre." This volume features 60 research reports by presenters with last names beginning between Abr…

  12. Proceedings of the Conference of the International Group for the Psychology of Mathematics Education (29th, Melbourne, Australia, July 10-15, 2005). Volume 2

    ERIC Educational Resources Information Center

    Chick, Helen L., Ed.; Vincent, Jill L., Ed.

    2005-01-01

    This document contains the second volume of the proceedings of the 29th Conference of the International Group for the Psychology of Mathematics Education. Conference papers are centered around the theme of "Learners and Learning Environments." This volume features 43 research reports by presenters with last names beginning between Adl…

  13. Diagnostic standards for dopaminergic augmentation of restless legs syndrome: report from a World Association of Sleep Medicine-International Restless Legs Syndrome Study Group consensus conference at the Max Planck Institute.

    PubMed

    García-Borreguero, Diego; Allen, Richard P; Kohnen, Ralf; Högl, Birgit; Trenkwalder, Claudia; Oertel, Wolfgang; Hening, Wayne A; Paulus, Walter; Rye, David; Walters, Arthur; Winkelmann, Juliane; Earley, Christopher J

    2007-08-01

    Augmentation of symptom severity is the main complication of dopaminergic treatment of restless legs syndrome (RLS). The current article reports on the considerations of augmentation that were made during a European Restless Legs Syndrome Study Group (EURLSSG)-sponsored Consensus Conference in April 2006 at the Max Planck Institute (MPI) in Munich, Germany, the conclusions of which were endorsed by the International RLS Study Group (IRLSSG) and the World Association of Sleep Medicine (WASM). The Consensus Conference sought to develop a better understanding of augmentation and generate a better operational definition for its clinical identification. Current concepts of the pathophysiology, clinical features, and therapy of RLS augmentation were evaluated by subgroups who presented a summary of their findings for general consideration and discussion. Recent data indicating sensitivity and specificity of augmentation features for identification of augmentation were also evaluated. The diagnostic criteria of augmentation developed at the National Institutes of Health (NIH) conference in 2002 were reviewed in light of current data and theoretical understanding of augmentation. The diagnostic value and criteria for each of the accepted features of augmentation were considered by the group. A consensus was then developed for a revised statement of the diagnostic criteria for augmentation. Five major diagnostic features of augmentation were identified: usual time of RLS symptom onset each day, number of body parts with RLS symptoms, latency to symptoms at rest, severity of the symptoms when they occur, and effects of dopaminergic medication on symptoms. The quantitative data available relating the time of RLS onset and the presence of other features indicated optimal augmentation criteria of either a 4-h advance in usual starting time for RLS symptoms or a combination of the occurrence of other features. A paradoxical response to changes in medication dose also indicates augmentation. Clinical significance of augmentation is defined. The Consensus Conference agreed upon new operational criteria for the clinical diagnosis of RLS augmentation: the MPI diagnostic criteria for augmentation. Areas needing further consideration for validating these criteria and for understanding the underlying biology of RLS augmentation are indicated.

  14. The Supervisory Process: A Consistent Approach to Help Student Teachers Improve.

    ERIC Educational Resources Information Center

    Blank, Mary Ann; Heathington, Betty S.

    1987-01-01

    The Office of Field Studies at the University of Tennessee Knoxville has implemented a research-based, collaborative-interactive student teacher supervision program featuring the provision of objective feedback during the preobservation conference, observation, and postobservation conference. (CB)

  15. A quark model analysis of the transversity distribution

    NASA Astrophysics Data System (ADS)

    Scopetta, Sergio; Vento, Vicente

    1998-04-01

    The feasibility of measuring chiral-odd parton distribution functions in polarized Drell-Yan and semi-inclusive experiments has renewed theoretical interest in their study. Models of hadron structure have proven successful in describing the gross features of the chiral-even structure functions. Similar expectations motivated our study of the transversity parton distributions in the Isgur-Karl and MIT bag models. We confirm, by performing a NLO calculation, the diverse low x behaviors of the transversity and spin structure functions at the experimental scale and show that it is fundamentally a consequence of the different behaviors under evolution of these functions. The inequalities of Soffer establish constraints between data and model calculations of the chiral-odd transversity function. The approximate compatibility of our model calculations with these constraints confers credibility to our estimates.

  16. APPA 2011 Conference Highlights

    ERIC Educational Resources Information Center

    Facilities Manager, 2011

    2011-01-01

    This article presents highlights of APPA conference that was held on July 16-18, 2011. The highlights feature photos of 2011-2012 board of directors, outgoing senior regional representatives to the board, meritorious service award, APPA fellow, president's recognition and gavel exchange, and diamond business partner award.

  17. A distance constrained synaptic plasticity model of C. elegans neuronal network

    NASA Astrophysics Data System (ADS)

    Badhwar, Rahul; Bagler, Ganesh

    2017-03-01

    Brain research has been driven by enquiry for principles of brain structure organization and its control mechanisms. The neuronal wiring map of C. elegans, the only complete connectome available till date, presents an incredible opportunity to learn basic governing principles that drive structure and function of its neuronal architecture. Despite its apparently simple nervous system, C. elegans is known to possess complex functions. The nervous system forms an important underlying framework which specifies phenotypic features associated to sensation, movement, conditioning and memory. In this study, with the help of graph theoretical models, we investigated the C. elegans neuronal network to identify network features that are critical for its control. The 'driver neurons' are associated with important biological functions such as reproduction, signalling processes and anatomical structural development. We created 1D and 2D network models of C. elegans neuronal system to probe the role of features that confer controllability and small world nature. The simple 1D ring model is critically poised for the number of feed forward motifs, neuronal clustering and characteristic path-length in response to synaptic rewiring, indicating optimal rewiring. Using empirically observed distance constraint in the neuronal network as a guiding principle, we created a distance constrained synaptic plasticity model that simultaneously explains small world nature, saturation of feed forward motifs as well as observed number of driver neurons. The distance constrained model suggests optimum long distance synaptic connections as a key feature specifying control of the network.

  18. Bringing Strategic Clarity to Your Grantmaking: Crafting and Using a Theory of Change. GFE Annual Conference (10th, San Francisco, California, November 6-8, 2006)

    ERIC Educational Resources Information Center

    Grantmakers for Education, 2006

    2006-01-01

    To provide an even more intensive learning experience at Grantmakers for Education's 2006 conference, the program featured a conference "study group." This special small-group program track focused on foundation strategy and the value of a well-crafted theory of change for increasing strategic clarity and impact. This report is intended to make…

  19. Proceedings of the Conference of the International Group for the Psychology of Mathematics Education (30th, Prague, Czech Republic, July 16-21, 2006). Volume 3

    ERIC Educational Resources Information Center

    Novotna, Jarmila, Ed.; Moraova, Hana, Ed.; Kratka, Magdalena, Ed.; Stehlikova, Nad'a, Ed.

    2006-01-01

    This document contains the third volume of the proceedings of the 30th Conference of the International Group for the Psychology of Mathematics Education. Conference presentations are centered around the theme "Mathematics at the Centre." This volume features 60 research reports by presenters with last names beginning between Ead and Kou:…

  20. Proceedings of the Conference of the International Group for the Psychology of Mathematics Education (30th, Prague, Czech Republic, July 16-21, 2006). Volume 5

    ERIC Educational Resources Information Center

    Novotna, Jarmila, Ed.; Moraova, Hana, Ed.; Kratka, Magdalena, Ed.; Stehlikova, Nad'a, Ed.

    2006-01-01

    This document contains the fifth volume of the proceedings of the 30th Conference of the International Group for the Psychology of Mathematics Education. Conference presentations are centered around the theme "Mathematics at the Centre." This volume features 59 research reports by presenters with last names beginning between Sac and Zaz:…

  1. Proceedings of the Conference of the International Group for the Psychology of Mathematics Education (29th, Melbourne, Australia, July 10-15, 2005). Volume 4

    ERIC Educational Resources Information Center

    Chick, Helen L., Ed.; Vincent, Jill L., Ed.

    2005-01-01

    This document is the fourth volume of the proceedings of the 29th Conference of the International Group for the Psychology of Mathematics Education. Conference papers are centered around the theme of "Learners and Learning Environments." This volume features 42 research reports by presenters with last names beginning between Mul and Wu:…

  2. Eighth DOD/NASA/FAA Conference on Fibrous Composites in Structural Design, Part 2

    NASA Technical Reports Server (NTRS)

    Starnes, James H., Jr. (Compiler); Bohon, Herman L. (Compiler); Garzon, Sherry B. (Compiler)

    1990-01-01

    Papers presented at the conference are compiled. The conference provided a forum for the scientific community to exchange composite structures design information and an opportunity to observe recent progress in composite structures design and technology. Part 2 contains papers related to the following subject areas: the application in design; methodology in design; and reliability in design.

  3. 16th International Conference on Nuclear Structure: NS2016

    DOE PAGES

    Galindo-Uribarri, Alfredo

    2016-10-28

    Every two years the Nuclear Structure (NS) conference series brings together researchers from an international community of experimental and theoretical nuclear physicists to present and discuss their latest results in nuclear structure. This biennial conference covered the latest results on experimental and theoretical research into the structure of nuclei at the extremes of isospin, excitation energy, mass, and angular momentum. Topics included many of the most exciting areas of modern nuclear structure research such as transitional behavior, nuclear structure and its evolution across the nuclear landscape, shell structure, collectivity, nuclear structure with radioactive beams, and macroscopic and microscopic approaches tomore » nuclear structure.« less

  4. 16th International Conference on Nuclear Structure: NS2016

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Galindo-Uribarri, Alfredo

    Every two years the Nuclear Structure (NS) conference series brings together researchers from an international community of experimental and theoretical nuclear physicists to present and discuss their latest results in nuclear structure. This biennial conference covered the latest results on experimental and theoretical research into the structure of nuclei at the extremes of isospin, excitation energy, mass, and angular momentum. Topics included many of the most exciting areas of modern nuclear structure research such as transitional behavior, nuclear structure and its evolution across the nuclear landscape, shell structure, collectivity, nuclear structure with radioactive beams, and macroscopic and microscopic approaches tomore » nuclear structure.« less

  5. Structure Elucidation of Coxsackievirus A16 in Complex with GPP3 Informs a Systematic Review of Highly Potent Capsid Binders to Enteroviruses.

    PubMed

    De Colibus, Luigi; Wang, Xiangxi; Tijsma, Aloys; Neyts, Johan; Spyrou, John A B; Ren, Jingshan; Grimes, Jonathan M; Puerstinger, Gerhard; Leyssen, Pieter; Fry, Elizabeth E; Rao, Zihe; Stuart, David I

    2015-10-01

    The replication of enterovirus 71 (EV71) and coxsackievirus A16 (CVA16), which are the major cause of hand, foot and mouth disease (HFMD) in children, can be inhibited by the capsid binder GPP3. Here, we present the crystal structure of CVA16 in complex with GPP3, which clarifies the role of the key residues involved in interactions with the inhibitor. Based on this model, in silico docking was performed to investigate the interactions with the two next-generation capsid binders NLD and ALD, which we show to be potent inhibitors of a panel of enteroviruses with potentially interesting pharmacological properties. A meta-analysis was performed using the available structural information to obtain a deeper insight into those structural features required for capsid binders to interact effectively and also those that confer broad-spectrum anti-enterovirus activity.

  6. Breath Analysis Science at PittCon 2012, Orlando, Florida

    EPA Science Inventory

    Breath analysis science was featured in three organized sessions at this year’s Pittsburgh Conference and Exposition, or ‘PittCon 2012’ (http://www.pittcon.org/). As described in previous meeting reports, PittCon is one of the largest international conferences for analytical chem...

  7. Promotion of Evidence-Based Nursing by Polish and foreign nursing organizations.

    PubMed

    Wasowska, Iga; Repka, Iwona

    2014-01-01

    The aim of the review was to obtain information on specific activities undertaken by professional nursing organizations, in order to promote and develop Evidence-Based Nursing (EBN). The foreign organizations featured in the study actively promote EBN within their countries of origin. This activity is currently focused on the structural and financial measures (focused on extrinsic factors). Some organizations are lobbying governments for grants and general support, in order to further their use and development of EBN. Educational activities are still ongoing, which include the creation of the creation of new guidelines and publishing research in journals, along with the organization of periodic conferences. Polish Nurses Association was the only one not involved in any structural and financial activities.

  8. The Fifth NASA/DOD Controls-Structures Interaction Technology Conference, part 2

    NASA Technical Reports Server (NTRS)

    Newsom, Jerry R. (Compiler)

    1993-01-01

    This publication is a compilation of the papers presented at the Fifth NASA/DoD Controls-Structures Interaction (CSI) Technology Conference held in Lake Tahoe, Nevada, March 3-5, 1992. The conference, which was jointly sponsored by the NASA Office of Aeronautics and Space Technology and the Department of Defense, was organized by the NASA Langley Research Center. The purpose of this conference was to report to industry, academia, and government agencies on the current status of controls-structures interaction technology. The agenda covered ground testing, integrated design, analysis, flight experiments and concepts.

  9. The Fifth NASA/DOD Controls-Structures Interaction Technology Conference, part 1

    NASA Technical Reports Server (NTRS)

    Newsom, Jerry R. (Compiler)

    1993-01-01

    This publication is a compilation of the papers presented at the Fifth NASA/DoD Controls-Structures Interaction (CSI) Technology Conference held in Lake Tahoe, Nevada, March 3-5, 1992. The conference, which was jointly sponsored by the NASA Office of Aeronautics and Space Technology and the Department of Defense, was organized by the NASA Langley Research Center. The purpose of this conference was to report to industry, academia, and government agencies on the current status of controls-structures interaction technology. The agenda covered ground testing, integrated design, analysis, flight experiments and concepts.

  10. Architecture of conference control functions

    NASA Astrophysics Data System (ADS)

    Kausar, Nadia; Crowcroft, Jon

    1999-11-01

    Conference control is an integral part in many-to-many communications that is used to manage and co-ordinate multiple users in conferences. There are different types of conferences which require different types of control. Some of the features of conference control may be user invoked while others are for internal management of a conference. In recent years, ITU (International Telecommunication Union) and IETF (Internet Engineering Task Force) have standardized two main models of conferencing, each system providing a set of conference control functionalities that are not easily provided in the other one. This paper analyzes the main activities appropriate for different types of conferences and presents an architecture for conference control called GCCP (Generic Conference Control Protocol). GCCP interworks different types of conferencing and provides a set of conference control functions that can be invoked by users directly. As an example of interworking, interoperation of IETF's SIP and ITU's H.323 call control functions have been examined here. This paper shows that a careful analysis of a conferencing architecture can provide a set of control functions essential for any group communication model that can be extensible if needed.

  11. FASEB Science Research Conference on Virus Structure and Assembly

    DTIC Science & Technology

    2017-10-24

    Report: FASEB Science Research Conference on Virus Structure and Assembly The views, opinions and/or findings contained in this report are those of the...SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS (ES) U.S. Army Research Office P.O. Box 12211 Research Triangle Park, NC 27709-2211 REPORT...Title: FASEB Science Research Conference on Virus Structure and Assembly Report Term: 0-Other Email: srcgrants@faseb.org Distribution Statement

  12. Creating a Nation of Innovators. A Brief Report

    ERIC Educational Resources Information Center

    Fluellen, Jerry E., Jr.

    2011-01-01

    The Learning and Brain Conference for 2011 featured talks on a handful of themes including creativity, technology, education tomorrow, five minds for the future and innovation. Of these, innovation took center stage. Tony Wagner's opening plenary session became the conference prologue, examining innovation from several perspectives including seven…

  13. InfoToday 2002 Collected Presentations (New York, New York, May 14-16, 2002).

    ERIC Educational Resources Information Center

    Nixon, Carol, Comp.; Burmood, Jennifer, Comp.

    This volume contains collected presentations (papers, outlines, and visual materials) from InfoToday 2002, the Global Conference & Exhibition on Electronic Information and Knowledge Management, featuring three core conferences for information professionals and knowledge managers: NationalOnline 2002, KnowledgeNets 2002, and E-Libraries 2002.…

  14. Technology 2003: The Fourth National Technology Transfer Conference and Exposition, volume 2

    NASA Technical Reports Server (NTRS)

    Hackett, Michael (Compiler)

    1994-01-01

    Proceedings from symposia of the Technology 2003 Conference and Exposition, Dec. 7-9, 1993, Anaheim, CA, are presented. Volume 2 features papers on artificial intelligence, CAD&E, computer hardware, computer software, information management, photonics, robotics, test and measurement, video and imaging, and virtual reality/simulation.

  15. Politics, the Media, and the Right to Know.

    ERIC Educational Resources Information Center

    Berry, John; And Others

    1992-01-01

    Report on the 1992 American Library Association (ALA) conference discusses featured speakers, political actions of the ALA Council, guidelines on patron behavior, the resignation of ALA Executive Director Linda Crismond, and conference exhibits. Excerpts from an address by new ALA president Marilyn Miller on empowering people through libraries are…

  16. Visual Discourse in Scientific Conference Papers: A Genre-based Study.

    ERIC Educational Resources Information Center

    Rowley-Jolivet, Elizabeth

    2002-01-01

    Investigates the role of visual communication in a spoken research genre: the scientific research paper. Analyzes 2,048 visuals projected during 90 papers given at five international conferences in three fields (Geology, medicine, physics), in order to bring out the recurrent features of the visual dimension. (Author/VWL)

  17. Prof. Hanna Neumann's Inaugural Presidential Address, 1966

    ERIC Educational Resources Information Center

    Neumann, Hanna

    2017-01-01

    Prof. Hanna Neumann gave the Presidential Address at Australian Association of Mathematics Teachers inaugural conference in 1966. The conference was held at Monash University and had the theme of "mathematical unity". In this address, Prof. Neumann described some features of the teaching of mathematics in schools. While she did not know…

  18. Technology 2003: The Fourth National Technology Transfer Conference and Exposition, volume 1

    NASA Technical Reports Server (NTRS)

    Hackett, Michael (Compiler)

    1994-01-01

    Proceedings from symposia of the Technology 2003 Conference and Exposition, December 7-9, 1993, Anaheim, CA, was discussed. Volume 1 features the Plenary Session and the Plenary Workshop, plus papers presented in Advanced Manufacturing, Biotechnology/Medical Technology, Environmental Technology, Materials Science, and Power and Energy.

  19. Past Project Expo Sites

    EPA Pesticide Factsheets

    This page provides information for Project Expo sites that were featured at the LMOP Conferences in 2013 and 2014. Project Expo sites were featured as being interested in identifying project partners for the development of an LFG energy project.

  20. Working Together to Educate about the Environment. Selected Papers from the Joint Conference of the North American Association for Environmental Education and the Conservation Education Association (Estes Park, Colorado, August 18-23, 1989).

    ERIC Educational Resources Information Center

    Gross, Michael P., Ed.; And Others

    Proceedings of a conference on environmental education are presented in this document. Featured at the conference were four general sessions, a number of additional invited presentations, three symposia, four workshops, and over 170 contributed presentations. The purpose of this volume is to provide a record of the papers presented at the…

  1. Building on Family Strengths: Research and Services in Support of Children and Their Families. Proceedings of the Building on Family Strengths Annual Conference (11th, Portland, Oregon, May 6-8, 2004)

    ERIC Educational Resources Information Center

    Gordon, Lynwood J., Ed.; Tullis, Kathryn, Ed.; Hanson, Andrea, Ed.; Sowders, Stacey, Ed.

    2005-01-01

    The 11th Annual Building on Family Strengths Conference was held from May 6th through May 8th, 2004, in Portland, Oregon. Highlights included: (1) The revival of a pre-conference training session; this year featured "Understanding Research and Evaluation in Relation to Social Change," presented by Elaine Slaton and Shannon CrossBear of…

  2. Identification of upstream and intragenic regulatory elements that confer cell-type-restricted and differentiation-specific expression on the muscle creatine kinase gene

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sternberg, E.A.; Spizz, G.; Perry, W.M.

    1988-07-01

    Terminal differentiation of skeletal myobalsts is accompanied by induction of a series of tissue-specific gene products, which includes the muscle isoenzymte of creatine kinase (MCK). To begin to define the sequences and signals involved in MCK regulation in developing muscle cells, the mouse MCK gene has been isolated. Sequence analysis of 4,147 bases of DNA surrounding the transcription initiation site revealed several interesting structural features, some of which are common to other muscle-specific genes and to cellular and viral enhancers.

  3. Special feature on imaging systems and techniques

    NASA Astrophysics Data System (ADS)

    Yang, Wuqiang; Giakos, George

    2013-07-01

    The IEEE International Conference on Imaging Systems and Techniques (IST'2012) was held in Manchester, UK, on 16-17 July 2012. The participants came from 26 countries or regions: Austria, Brazil, Canada, China, Denmark, France, Germany, Greece, India, Iran, Iraq, Italy, Japan, Korea, Latvia, Malaysia, Norway, Poland, Portugal, Sweden, Switzerland, Taiwan, Tunisia, UAE, UK and USA. The technical program of the conference consisted of a series of scientific and technical sessions, exploring physical principles, engineering and applications of new imaging systems and techniques, as reflected by the diversity of the submitted papers. Following a rigorous review process, a total of 123 papers were accepted, and they were organized into 30 oral presentation sessions and a poster session. In addition, six invited keynotes were arranged. The conference not only provided the participants with a unique opportunity to exchange ideas and disseminate research outcomes but also paved a way to establish global collaboration. Following the IST'2012, a total of 55 papers, which were technically extended substantially from their versions in the conference proceeding, were submitted as regular papers to this special feature of Measurement Science and Technology . Following a rigorous reviewing process, 25 papers have been finally accepted for publication in this special feature and they are organized into three categories: (1) industrial tomography, (2) imaging systems and techniques and (3) image processing. These papers not only present the latest developments in the field of imaging systems and techniques but also offer potential solutions to existing problems. We hope that this special feature provides a good reference for researchers who are active in the field and will serve as a catalyst to trigger further research. It has been our great pleasure to be the guest editors of this special feature. We would like to thank the authors for their contributions, without which it would not be possible to have this special feature published. We are grateful to all reviewers, who devoted their time and effort, on a voluntary basis, to ensure that all submissions were reviewed rigorously and fairly. The publishing staff of Measurement Science and Technology are particularly acknowledged for giving us timely advice on guest-editing this special feature.

  4. Support for 26th International Conference on Neutrino Physics and Astrophysics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kearns, Edward; Feldman, Gary

    The XXVI International Conference on Neutrino Physics and Astrophysics (Neutrino 2014) was held in Boston, U.S.A. from June 2 to 7, 2014. The Conference was co-­hosted by Boston University, Harvard University, M.I.T., and Tufts University. The Conference welcomed 549 registered participants from 33 countries. The Boston University Student Village offered an inexpensive housing option and was taken advantage of by 282 attendees. The lecture venue was the George Sherman Union at Boston University. There were 63 scientific presentations by speakers from 15 countries. The Conference held two poster sessions with a total of 287 posters. The Conference featured a receptionmore » at the M.I.T. Museum plus a multi-­week exhibition on neutrino physics capped by public presentations on the closing date of the conference. The banquet was a strolling buffet dinner held at the New England Aquarium.« less

  5. Towards big data science in the decade ahead from ten years of InCoB and the 1st ISCB-Asia Joint Conference

    PubMed Central

    2011-01-01

    The 2011 International Conference on Bioinformatics (InCoB) conference, which is the annual scientific conference of the Asia-Pacific Bioinformatics Network (APBioNet), is hosted by Kuala Lumpur, Malaysia, is co-organized with the first ISCB-Asia conference of the International Society for Computational Biology (ISCB). InCoB and the sequencing of the human genome are both celebrating their tenth anniversaries and InCoB’s goalposts for the next decade, implementing standards in bioinformatics and globally distributed computational networks, will be discussed and adopted at this conference. Of the 49 manuscripts (selected from 104 submissions) accepted to BMC Genomics and BMC Bioinformatics conference supplements, 24 are featured in this issue, covering software tools, genome/proteome analysis, systems biology (networks, pathways, bioimaging) and drug discovery and design. PMID:22372736

  6. FIBER-TEX 1991: The Fifth Conference on Advanced Engineering Fibers and Textile Structures for Composites

    NASA Technical Reports Server (NTRS)

    Buckley, John D. (Editor)

    1992-01-01

    This document is a compilation of papers presented at a joint NASA/North Carolina State University/DoD/Clemson University/Drexel University conference on Fibers, Textile Technology, and Composites Structures held at the College of Textiles Building on Centennial Campus of North Carolina State University, Raleigh, North Carolina on October 15-17, 1991. Conference papers presented information on advanced engineering fibers, textile processes and structures, structural fabric production, mechanics and characteristics of woven composites, pultruded composites, and the latest requirements for the use of textiles in the production of composite materials and structures.

  7. FIBER-TEX 1992: The Sixth Conference on Advanced Engineering Fibers and Textile Structures for Composites

    NASA Technical Reports Server (NTRS)

    Buckley, John D. (Editor)

    1993-01-01

    The FIBER-TEX 1992 proceedings contain the papers presented at the conference held on 27-29 Oct. 1992 at Drexel University. The conference was held to create a forum to encourage an interrelationship of the various disciplines involved in the fabrication of materials, the types of equipment, and the processes used in the production of advanced composite structures. Topics discussed were advanced engineering fibers, textile processes and structures, structural fabric production, mechanics and characteristics of woven composites, and the latest requirements for the use of textiles in the production of composite materials and structures as related to global activities focused on textile structural composites.

  8. Ancestral multipartite units in light-responsive plant promoters have structural features correlating with specific phototransduction pathways.

    PubMed Central

    Argüello-Astorga, G R; Herrera-Estrella, L R

    1996-01-01

    Regulation of plant gene transcription by light is mediated by multipartite cis-regulatory units. Previous attempts to identify structural features that are common to all light-responsive elements (LREs) have been unsuccessful. To address the question of what is needed to confer photoresponsiveness to a promoter, the upstream sequences from more than 110 light-regulated plant genes were analyzed by a new, phylogenetic-structural method. As a result, 30 distinct conserved DNA module arrays (CMAs) associated with light-responsive promoter regions were identified. Several of these CMAs have remained invariant throughout the evolutionary radiation of angiosperms and are conserved between homologous genes as well as between members of different gene families. The identified CMAs share a gene superfamily-specific core that correlates with the particular phytochrome-dependent transduction pathway that controls their expression, i.e. ACCTA(A/C)C(A/C) for the cGMP-dependent phenylpropanoid metabolism-associated genes, and GATA(A/T)GR for the Ca2+/calmodulin-dependent photosynthesis-associated nuclear genes. In addition to suggesting a general model for the functional and structural organization of LREs, the data obtained in this study indicate that angiosperm LREs probably evolved from complex cis-acting elements involved in regulatory processes other than photoregulation in gymnosperms. PMID:8938415

  9. Structural Basis for the Species-Selective Binding of N,C-Capped Dipeptides to the Mycobacterium tuberculosis Proteasome

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hsu, Hao-Chi; Singh, Pradeep K.; Fan, Hao

    The Mycobacterium tuberculosis (Mtb) 20S proteasome is vital for the pathogen to survive under nitrosative stress in vitro and to persist in mice. To qualify for drug development, inhibitors targeting Mtb 20S must spare both the human constitutive proteasome (c-20S) and immunoproteasome (i-20S). We recently reported members of a family of noncovalently binding dipeptide proteasome inhibitors that are highly potent and selective for Mtb 20S over human c-20S and i-20S. To understand the structural basis of their potency and selectivity, we have studied the structure–activity relationship of six derivatives and solved their cocrystal structures with Mtb 20S. The dipeptide inhibitorsmore » form an antiparallel β-strand with the active site β-strands. Selectivity is conferred by several features of Mtb 20S relative to its mouse counterparts, including a larger S1 pocket, additional hydrogen bonds in the S3 pocket, and hydrophobic interactions in the S4 pocket. Serine-20 and glutamine-22 of Mtb 20S interact with the dipeptides and confer Mtb-specific inhibition over c-20S and i-20S. The Mtb 20S and mammalian i-20S have a serine-27 that interacts strongly with the dipeptides, potentially explaining the higher inhibitory activity of the dipeptides toward i-20S over c-20S. This detailed structural knowledge will aid in optimizing the dipeptides as anti-tuberculosis drugs.« less

  10. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schroeder, Julian I

    The 19th International Conference on Arabidopsis Research was a successful meeting attended by 815 scientists from around the world including 322 from the United States, 146 attendees from Canada, 179 from Europe, 134 from Asia, and 34 from a combination of Australia, South America, Africa and the Middle East. The scientific program was of excellent quality featuring 64 talks, including 41 from invited speakers. The Keynote Lecture, delivered by Chris Somerville (Energy Biosciences Institute/UC Berkeley) was particularly relevant to US agriculture and energy research and was titled The Development of Cellulosic Biofuels. There were also 6 community-organized workshops featuring 30more » additional talks on topics including Frontiers in Plant Systems Biology, Sources and strategies for Gene Structure, Gene Function, and Metabolic Pathway annotation at TAIR and AraCyc, Advanced Bioinformatic Resources for Arabidopsis, Laser Microtechniques and Applications with Arabidopsis, Plant Proteomics- Tools, Approaches, Standards and Breakthroughs in Studying the Proteome, and Phytohormone Biosynthesis and Signal Transduction. Conference organizers arranged a special seminar by Jim Collins (head of the Directorate of Biosciences at NSF) to provide a community discussion forum regarding the future of Arabidopsis research. Approximately 575 posters were presented in topic areas including, among others, Development, Signal Transduction, Cell Walls, Non-Arabidopsis Systems, and Interactions with Biotic and Abiotic Factors. All conference abstracts and the full program are posted at The Arabidopsis Information Resource (TAIR), a publicly-accessibly website (www.arabidopsis.org/news/abstracts.jsp.) A survey completed by approximately 40% of the meeting attendees showed high satisfaction with the quality of the presentations, meeting organization and the city of Montreal. The conference is the largest annual international Arabidopsis venue which allowed the exchange of information at the forefront of Arabidopsis research and facilitated the establishment of new, and the strengthening of old, collaborations and networks. In addition, the conference provides the site for the annual meetings of the Multinational Arabidopsis Steering Committee (MASC) and the North American Arabidopsis Steering Committee (NAASC.) Graduate students, postdoctoral researchers, junior faculty, and underrepresented minorities made up half of the oral presentations thereby promoting the training of young scientists and facilitating important career development opportunities for speakers. Several poster sessions provided an opportunity for younger participants to freely meet with more established scientists. The NAASC continued its outreach efforts and again sponsored two special luncheons to encourage personal and professional development of young scientists and underrepresented minorities. The Emerging Scientists Luncheon featured 8 graduate students selected on the basis of scientific excellence of their submitted research abstracts. Also attending were the Keynote Speaker and faculty conference organizers. The Minority Funding Luncheon, featured 7 awardees (2 female graduate students, 2 female faculty, 2 male graduate students and 1 male faculty) selected by the NAASC through a widely-publicized application process. This luncheon was established specifically to provide an opportunity for underrepresented minorities, and/or scientists from Minority-Serving Institutions/Historically Black Colleges and Universities to network with NAASC members and representatives from federal funding agencies in an informal and intimate setting. This luncheon included introductions of each award recipient and discussion of outreach efforts and informal research and career discussions. Staff members from The Arabidopsis Information Resource (TAIR), the public U.S. Arabidopsis bioinformatics resource, led one workshop and participated in another to convey information to the community about Arabidopsis resources. Participation by young researchers was facilitated through DOE-sponsored registration awards to 10 early career applicants from the US including five graduate students, four postdoctoral scholars and one new assistant faculty member.« less

  11. Iridescence: views from many angles

    PubMed Central

    Meadows, Melissa G.; Butler, Michael W.; Morehouse, Nathan I.; Taylor, Lisa A.; Toomey, Matthew B.; McGraw, Kevin J.; Rutowski, Ronald L.

    2009-01-01

    Iridescent colours have been fascinating to humans throughout history; they are flashy, shimmering, dynamic, and examples surround us, from the commonly seen iridescent sheen of oily street puddles to the exotic, gaudy displays of birds-of-paradise featured in nature documentaries. Iridescent colours and the structures that produce them have unique properties in comparison with other types of colourants found in nature. Scientists from a variety of disciplines study the optics, development, heritability, chemical make-up, origin, evolution, functions and biomimetic technological applications of naturally occurring iridescent colours. For the first time, graduate students at Arizona State University brought together these scientists, along with educators and artists, at ‘Iridescence: more than meets the eye’, a conference to promote interdisciplinary communication and collaboration in the study of iridescent coloration from all of these perspectives. Here, we summarize the outcomes of this conference, introduce the papers that follow in this special journal issue and briefly review the current status of our understanding of iridescence. PMID:19336343

  12. Intra-specific diversity of Serratia marcescens in Anopheles mosquito midgut defines Plasmodium transmission capacity

    PubMed Central

    Bando, Hironori; Okado, Kiyoshi; Guelbeogo, Wamdaogo M.; Badolo, Athanase; Aonuma, Hiroka; Nelson, Bryce; Fukumoto, Shinya; Xuan, Xuenan; Sagnon, N'Fale; Kanuka, Hirotaka

    2013-01-01

    A critical stage in malaria transmission occurs in the Anopheles mosquito midgut, when the malaria parasite, Plasmodium, ingested with blood, first makes contact with the gut epithelial surface. To understand the response mechanisms within the midgut environment, including those influenced by resident microbiota against Plasmodium, we focus on a midgut bacteria species' intra-specific variation that confers diversity to the mosquito's competency for malaria transmission. Serratia marcescens isolated from either laboratory-reared mosquitoes or wild populations in Burkina Faso shows great phenotypic variation in its cellular and structural features. Importantly, this variation is directly correlated with its ability to inhibit Plasmodium development within the mosquito midgut. Furthermore, this anti-Plasmodium function conferred by Serratia marcescens requires increased expression of the flagellum biosynthetic pathway that is modulated by the motility master regulatory operon, flhDC. These findings point to new strategies for controlling malaria through genetic manipulation of midgut bacteria within the mosquito. PMID:23571408

  13. Special Issue of Selected Papers from Visualization and Data Analysis 2011

    NASA Technical Reports Server (NTRS)

    Kao, David L.; Wong, Pak Chung

    2012-01-01

    This special issue features the best papers that were selected from the 18th SPIE Conference on Visualization and Data Analysis (VDA 2011). This annual conference is a major international forum for researchers and practitioners interested in data visualization and analytics research, development, and applications. VDA 2011 received 42 high-quality submissions from around the world. Twenty-four papers were selected for full conference papers. The top five papers have been expanded and reviewed for this special issue.

  14. National Conference on the Development of Statewide Preservation Programs. Report of a Conference on the Current Status and Future Directions of Statewide Programs for the Preservation of Our Intellectual Heritage (Washington, D.C., March 1-3, 1989).

    ERIC Educational Resources Information Center

    Morrow, Carolyn Clark, Ed.

    This report presents some of the prominent features of a national invitational conference whose goal was to provide a national forum to discuss ongoing preservation efforts in individual states; describe the preservation challenge faced by all states in common; review the kinds of materials at risk; and alert administrators to the opportunities…

  15. Paired Learning: Tutoring by Non-Teachers. Incorporating "The Paired Reading Bulletin" No. 5.

    ERIC Educational Resources Information Center

    Paired Reading Bulletin, 1989

    1989-01-01

    The eight papers constituting the Proceedings of the fourth National Paired Reading Conference are published in an annual bulletin of the Paired Reading Project, together with seven papers constituting the Supplementary Proceedings of the Peer Tutoring Conference, and nine feature articles, as follows: (1) "Whole-School Policy on Parental…

  16. Environmental Science Conference for State Supervisors of Science (Portland State University, Portland, Oregon, May 1-5, 1970).

    ERIC Educational Resources Information Center

    Portland State Univ., OR.

    The Conference report reviewed the status of man's environment and drafted guidelines for state education agencies to use for developing state programs related to environmental education. The six featured speakers and topics were: Kessler Cannon--"Report of the Governor's Committee on Natural Resources;" Dr. Harry…

  17. 2012 Gordon Research Conference on Cellular and Molecular Fungal Biology, Final Progress Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Berman, Judith

    The Gordon Research Conference on Cellular and Molecular Fungal Biology was held at Holderness School, Holderness New Hampshire, June 17 - 22, 2012. The 2012 Gordon Conference on Cellular and Molecular Fungal Biology (CMFB) will present the latest, cutting-edge research on the exciting and growing field of molecular and cellular aspects of fungal biology. Topics will range from yeast to filamentous fungi, from model systems to economically important organisms, and from saprophytes and commensals to pathogens of plants and animals. The CMFB conference will feature a wide range of topics including systems biology, cell biology and morphogenesis, organismal interactions, genomemore » organisation and regulation, pathogenesis, energy metabolism, biomass production and population genomics. The Conference was well-attended with 136 participants. Gordon Research Conferences does not permit publication of meeting proceedings.« less

  18. Embedded Incremental Feature Selection for Reinforcement Learning

    DTIC Science & Technology

    2012-05-01

    Prior to this work, feature selection for reinforce- ment learning has focused on linear value function ap- proximation ( Kolter and Ng, 2009; Parr et al...InProceed- ings of the the 23rd International Conference on Ma- chine Learning, pages 449–456. Kolter , J. Z. and Ng, A. Y. (2009). Regularization and feature

  19. Intakes conference: understanding the impact of resident autonomy on a morning report conference.

    PubMed

    Moreno, Megan A; Shaffer, David Williamson

    2006-01-01

    Morning report (MR) is one of the most common conferences in medical residency training. Literature has suggested that an imposed structure is necessary for success. However, studies have suggested that rigid structure may decrease resident motivation. Three goals of a successful MR include large breadth of presented cases, high resident participation, and well-formatted presentations. In this article, we present a qualitative case analysis of an unstructured resident- led MR and analyze breadth of cases, resident participation, and presentation format. We collected data that included case presentation tracking, video recording conferences, and interviewing residents and faculty. Case presentations covered a broad range of topics with little duplication (2.2%). Residents preformed most (94%) of presentations; most residents (92.3%) presented cases. Case presentations were structured in 1 of 3 formats that fulfilled suggested guidelines from MR literature. In this unstructured MR conference, structural aims were met with the relatively autonomous decisions of motivated resident participants.

  20. [Plasticity of bacterial genomes: pathogenicity islands and the locus of enterocyte effacement (LEE)].

    PubMed

    Kirsch, Petra; Jores, Jörg; Wieler, Lothar H

    2004-01-01

    Many bacterial virulence attributes, like toxins, adhesins, invasins, iron uptake systems, are encoded within specific regions of the bacterial genome. These in size varying regions are termed pathogenicity islands (PAIs) since they confer pathogenic properties to the respective micro-organism. Per definition PAIs are exclusively found in pathogenic strains and are often inserted near transfer-RNA genes. Nevertheless, non-pathogenic bacteria also possess foreign DNA elements that confer advantageous features, leading to improved fitness. These additional DNA elements as well as PAIs are termed genomic islands and were acquired during bacterial evolution. Significant G+C content deviation in pathogenicity islands with respect to the rest of the genome, the presence of direct repeat sequences at the flanking regions, the presence of integrase gene determinants as other mobility features,the particular insertion site (tRNA gene) as well as the observed genetic instability suggests that pathogenicity islands were acquired by horizontal gene transfer. PAIs are the fascinating proof of the plasticity of bacterial genomes. PAIs were originally described in human pathogenic Escherichia (E.) coli strains. In the meantime PAIs have been found in various pathogenic bacteria of humans, animals and even plants. The Locus of Enterocyte Effacement (LEE) is one particular widely distributed PAI of E coli. In addition, it also confers pathogenicity to the related species Citrobacter (C.) rodentium and Escherichia (E.) alvei. The LEE is an important virulence feature of several animal pathogens. It is an obligate PAI of all animal and human enteropathogenic E. coli (EPEC), and most enterohaemorrhegic E. coli (EHEC) also harbor the LEE. The LEE encodes a type III secretion system, an adhesion (intimin) that mediates the intimate contact between the bacterium and the epithelial cell, as well as various proteins which are secreted via the type III secretion system. The LEE encoded virulence features are responsible for the formation of so called attaching and effacing (AE) lesions in the intestinal epithelium. Due to its wide distribution in animal pathogens, LEE encoded antigens are suitable vaccine antigens. Acquisition and structure of the LEE pathogenicity island is the crucial point of numerous investigations. However, the evolution of the LEE, its origin and further spread in E. coli, are far from being resolved.

  1. Tracking discourse complexity preceding Alzheimer's disease diagnosis: a case study comparing the press conferences of Presidents Ronald Reagan and George Herbert Walker Bush.

    PubMed

    Berisha, Visar; Wang, Shuai; LaCross, Amy; Liss, Julie

    2015-01-01

    Changes in some lexical features of language have been associated with the onset and progression of Alzheimer's disease. Here we describe a method to extract key features from discourse transcripts, which we evaluated on non-scripted news conferences from President Ronald Reagan, who was diagnosed with Alzheimer's disease in 1994, and President George Herbert Walker Bush, who has no known diagnosis of Alzheimer's disease. Key word counts previously associated with cognitive decline in Alzheimer's disease were extracted and regression analyses were conducted. President Reagan showed a significant reduction in the number of unique words over time and a significant increase in conversational fillers and non-specific nouns over time. There was no significant trend in these features for President Bush.

  2. Mn@Si14+: a singlet fullerene-like endohedrally doped silicon cluster.

    PubMed

    Ngan, Vu Thi; Pierloot, Kristine; Nguyen, Minh Tho

    2013-04-21

    The electronic structure of Mn@Si14(+) is determined using DFT and CASPT2/CASSCF(14,15) computations with large basis sets. The endohedrally Mn-doped Si cationic cluster has a D3h fullerene-like structure featuring a closed-shell singlet ground state with a singlet-triplet gap of ~1 eV. A strong stabilizing interaction occurs between the 3d(Mn) and the 2D-shell(Si14) orbitals, and a large amount of charge is transferred from the Si14 cage to the Mn dopant. The 3d(Mn) orbitals are filled by encapsulation, and the magnetic moment of Mn is completely quenched. Full occupation of [2S, 2P, 2D] shell orbitals by 18 delocalized electrons confers the doped Mn@Si14(+) cluster a spherically aromatic character.

  3. Mechatronics 2012

    NASA Astrophysics Data System (ADS)

    Scheidl, Rudolf; Jakoby, Bernhard

    2013-08-01

    Following the 2010 conference held at ETH Zurich, the 13th renowned International Mechatronics Forum Conference--Mechatronics 2012--took place from 17-19 September 2012. Held in Austria for the first time, it was jointly organized by the Johannes Kepler University and the Austrian Center for Competence in Mechatronics (ACCM). In accordance with the Local and International Organizing Committee, we opened new avenues to make this conference more attractive, particularly to industry. Mini-symposia were set up devoted to specific topics. This proved successful in attracting certain scientific communities and groups and gave the conference a broader scope and a more colourful appearance. Another successful attempt was to involve industry more strongly than in previous conferences. The conference's character was influenced by the approach and the specific mechatronic problems of the Linz area in industry, teaching and research. This concept of showcasing the local situation in mechatronics in these areas could be valuable for the future conferences; the international mechatronics community could get an overview about the different interpretations of mechatronics and could form informed opinions about different approaches. Around 150 lecturers from 23 countries around the world covered a broad spectrum of approaches to mechatronic problem solutions, of new technologies, scientific and engineering methods and methodologies. Authors of conference papers in the area of sensors and measurement technology were invited to submit extended papers for publication in this special feature in Measurement Science and Technology , which were all fully peer-reviewed. The topics of the papers that are now collected in this special feature illustrate this variety, from the application of measurement systems to microsystems and algorithms. We are grateful to the editors of Measurement Science and Technology for the opportunity to provide a glimpse of the results presented at the conference and would like to thank IOP Publishing staff for the efficient handling of the entire publication process!

  4. PREFACE: Nanoscale Devices and System Integration Conference (NDSI-2004)

    NASA Astrophysics Data System (ADS)

    Khizroev, Sakhrat; Litvinov, Dmitri

    2004-10-01

    The inaugural conference on Nanoscale Devices and System Integration (NDSI-2004) was held in Miami, Florida, 15-19 February, 2004. The focus of the conference was `real-life' devices and systems that have recently emerged as a result of various nanotechnology initiatives in chemistry and chemical engineering, physics, electrical engineering, materials science and engineering, biomedical engineering, computer science, robotics, and environmental science. The conference had a single session all-invited speaker format, with the presenters making the `Who's Who in Nanotechnology' list. Contributed work was showcased at a special poster session. The conference, sponsored by the Institute of Electrical and Electronics Engineers (IEEE) and the US Air Force, and endorsed by Materials Research Society (MRS), drew more than 160 participants from fourteen countries. To strengthen the connection between fundamental research and `real-life' applications, the conference featured a large number of presenters from both academia and industry. Among the participating companies were NEC, IBM, Toshiba, AMD, Samsung, Seagate, and Veeco. Nanotechnology has triggered a new wave of research collaborations between researchers from academia and industry with a broad range of specializations. Such a global approach has resulted in a number of breakthrough accomplishments. One of the main goals of this conference was to identify these accomplishments and put the novel technology initiatives and the emerging research teams on the map. Among the key nanotechnology applications demonstrated at NDSI-2004 were carbon-nanotube-based transistors, quantum computing systems, nanophotonic devices, single-molecule electronic devices and biological magnetic sources. Due to the unprecedented success of the conference, the organizing committee of NDSI has unanimously chosen to turn NDSI into an annual international nanotechnology event. The next NDSI is scheduled for 4-6 April, 2005, in Houston, Texas. Details can be found on the conference web site at http://www.nanointernational.org. This special issue of Nanotechnology features selected papers from NDSI-2004.

  5. NCSE's 15th National Conference and Global Forum on Science, Policy, and the Environment: Energy and Climate Change, Final Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Levine, Ellen

    The National Council for Science and the Environment (NCSE) held its 15th National Conference and Global Forum on Science, Policy and the Environment: Energy and Climate Change, on January 27-29, 2015, at the Hyatt Regency Hotel, Crystal City, VA. The National Conference: Energy and Climate Change developed and advanced partnerships that focused on transitioning the world to a new “low carbon” and “climate resilient” energy system. It emphasized advancing research and technology, putting ideas into action, and moving forward on policy and practice. More than 900 participants from the scientific research, policy and governance, business and civil society, and educationmore » communities attended. The Conference was organized around four themes: (1) a new energy system (including energy infrastructure, technologies and efficiencies, changes in distribution of energy sources, and low carbon transportation); (2) energy, climate and sustainable development; (3) financing and markets; and (4) achieving progress (including ideas for the 21st Conference of Parties to the United Nations Framework Convention on Climate Change). The program featured six keynote presentations, six plenary sessions, 41 symposia and 20 workshops. Conference participants were involved in the 20 workshops, each on a specific energy and climate-related issue. The workshops were designed as interactive sessions, with each workshop generating 10-12 recommendations on the topic. The recommendations were prepared in the final conference report, were disseminated nationally, and continue to be available for public use. The conference also featured an exhibition and poster sessions. The National Conference on Energy and Climate Change addressed a wide range of issues specific to the U.S. Department of Energy’s programs; involved DOE’s scientists and program managers in sessions and workshops; and reached out to a broad array of DOE stakeholders.« less

  6. THE BRAIN-INJURED CHILD, A SUMMARY REPORT OF CONFERENCE ON THE CHILD WITH LEARNING DISABILITIES (JERSEY CITY, MARCH 25, 1965).

    ERIC Educational Resources Information Center

    EZOR, EDWIN; RUVIN, HAROLD

    THE BASIC VIEWPOINT OF THIS CONFERENCE IS THAT CHILDREN WITH LEARNING DISABILITIES MUST BE EVALUATED INDIVIDUALLY ACCORDING TO THEIR SPECIFIC DYSFUNCTIONS AND PLACED IN EDUCATIONAL SETTINGS ACCORDING TO THEIR INDIVIDUAL NEEDS. IN THE FEATURED ADDRESS, "NEW APPROACHES IN EDUCATION FOR THE CHILD WITH LEARNING DISABILITIES," BARBARA BATEMAN…

  7. Curriculum and Testing Strategies to Maximize Special Education STAAR Achievement

    ERIC Educational Resources Information Center

    Johnson, William L.; Johnson, Annabel M.; Johnson, Jared W.

    2015-01-01

    This document is from a presentation at the 2015 annual conference of the Science Teachers Association of Texas (STAT). The two sessions (each listed as feature sessions at the state conference) examined classroom strategies the presenter used in his chemistry classes to maximize Texas end-of-course chemistry test scores for his special population…

  8. Hawaii Literacy Hui Conference, 1997: Changing Lives, Building Communities. [Videotape].

    ERIC Educational Resources Information Center

    Darling-Hammond, Linda; Holt, Linda

    This videotape presents the keynote speeches of the 1997 Hawai'i Literacy Hui conference on the theme of "Changing Lives, Building Communities." Featured in the videotape are two speeches: Linda Darling-Hammond's "The Right To Learn and Teach: Towards Democratic Education," in which she discusses how authentic assessment in the context of the new…

  9. Technology 2001: The Second National Technology Transfer Conference and Exposition, volume 1

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Papers from the technical sessions of the Technology 2001 Conference and Exposition are presented. The technical sessions featured discussions of advanced manufacturing, artificial intelligence, biotechnology, computer graphics and simulation, communications, data and information management, electronics, electro-optics, environmental technology, life sciences, materials science, medical advances, robotics, software engineering, and test and measurement.

  10. Interpreting as a Language Teaching Technique. Proceedings of a Conference (University of Salford, England, January 2-5, 1985).

    ERIC Educational Resources Information Center

    Thomas, Noel, Ed.; Towell, Richard, Ed.

    Papers presented at a conference on the use of simultaneous, consecutive, and other forms of interpreting as features of foreign language teaching and learning in British higher education include the following: "Liaison Interpreting as a Communicative Language-Learning Exercise" (H. A. Keith); "Interpreting and Communicating:…

  11. Introducing a Morbidity and Mortality Conference in Rwanda.

    PubMed

    Abahuje, Egide; Nzeyimana, Innocent; Rickard, Jennifer L

    To assess the structure, format, and educational features of a morbidity and mortality (M&M) conference in Rwanda. To determine factors associated with adverse events and to define opportunities for improvement. Retrospective, descriptive study of all cases presented at a surgical M&M conference over a 1-year period. Cases were reviewed for factors associated with adverse events and opportunities for improvement. Factors were characterized as delays in presentation, delays in diagnosis, delays in the operating room, errors in judgment, technical errors, advanced disease, and missing resources or malnutrition. Opportunities for improvement were categorized at the physician or hospital level. University Teaching Hospital of Kigali, a tertiary referral hospital in Rwanda. Cases presented at the surgical M&M conference over a 1-year period. Over a 1-year period, there were a total of 2231 operations with 131 in-hospital mortalities. There were 62 patients discussed at M&M conference. Of those discussed, there were 34 (55%) in-hospital deaths and 32 (52%) unplanned reoperations. Common diagnostic categories included 30 (48%) gastrointestinal, 15 (24%) trauma, and 10 (16%) neoplasm. Delays were commonly cited factors affecting outcomes. There were 22 (35%) delays in presentation, 23 (37%) delays in diagnosis or management, and 20 (32%) delays to the operating room. Errors in judgment occurred in 15 (24%) cases and technical errors occurred in 18 (29%) cases. Twenty-three (37%) patients had a critical resource missing and 17 (27%) patients had advanced disease. Malnutrition was associated with 11 (18%) adverse events. Participants identified opportunities for improvement in 48 (77%) cases. M&M conference can be used in a low-resource setting as an educational tool to address core competencies of practice-based learning and improvement and systems-based practice. It can define factors associated with surgical adverse events and opportunities for improvement at the physician and hospital levels. Copyright © 2017 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

  12. PREFACE: 2nd International Conference on Innovative Materials, Structures and Technologies

    NASA Astrophysics Data System (ADS)

    Ručevskis, Sandris

    2015-11-01

    The 2nd International Conference on Innovative Materials, Structures and Technologies (IMST 2015) took place in Riga, Latvia from 30th September - 2nd October, 2015. The first event of the conference series, dedicated to the 150th anniversary of the Faculty of Civil Engineering of Riga Technical University, was held in 2013. Following the established tradition, the aim of the conference was to promote and discuss the latest results of industrial and academic research carried out in the following engineering fields: analysis and design of advanced structures and buildings; innovative, ecological and energy efficient building materials; maintenance, inspection and monitoring methods; construction technologies; structural management; sustainable and safe transport infrastructure; and geomatics and geotechnics. The conference provided an excellent opportunity for leading researchers, representatives of the industrial community, engineers, managers and students to share the latest achievements, discuss recent advances and highlight the current challenges. IMST 2015 attracted over 120 scientists from 24 countries. After rigorous reviewing, over 80 technical papers were accepted for publication in the conference proceedings. On behalf of the organizing committee I would like to thank all the speakers, authors, session chairs and reviewers for their efficient and timely effort. The 2nd International Conference on Innovative Materials, Structures and Technologies was organized by the Faculty of Civil Engineering of Riga Technical University with the support of the Latvia State Research Programme under the grant agreement "INNOVATIVE MATERIALS AND SMART TECHNOLOGIES FOR ENVIRONMENTAL SAFETY, IMATEH". I would like to express sincere gratitude to Juris Smirnovs, Dean of the Faculty of Civil Engineering, and Andris Chate, manager of the Latvia State Research Programme. Finally, I would like to thank all those who helped to make this event happen. Special thanks go to Diana Bajare, Laura Sele, Liga Radina and Jana Galilejeva for their major contribution to organizing the conference and to the literary editor Tatjana Smirnova and technical editor Daira Erdmane for their hard work on the conference proceedings.

  13. 2004 Reversible Associations in Structure & Molecular Biology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Edward Eisenstein Nancy Ryan Gray

    The Gordon Research Conference (GRC) on 2004 Gordon Research Conference on Reversible Associations in Structure & Molecular Biology was held at Four Points Sheraton, CA, 1/25-30/2004. The Conference was well attended with 82 participants (attendees list attached). The attendees represented the spectrum of endeavor in this field coming from academia, industry, and government laboratories, both U.S. and foreign scientists, senior researchers, young investigators, and students.

  14. PREFACE: 12th Europhysical Conference on Defects in Insulating Materials (EURODIM 2014)

    NASA Astrophysics Data System (ADS)

    Alfredsson, M. L.; Chadwick, A. V.; Jackson, R. A.; McCabe, E. E.

    2015-04-01

    The 12th Europhysical Conference on Defects in Insulating Materials (EURODIM14) was held at the University of Kent, UK, from 13-18 July 2014. It was attended by about 120 delegates from around the world, and featured 56 oral presentations and 77 posters. EURODIM14 followed other conferences in the series, held in Pecs (2010), Milan (2006) and Wroclaw (2002), as well as the related ICDIM conferences held in Santa Fe (2012), Aracaju (2008) and Riga (2004). These conferences all have the aim of bringing together scientists to discuss the chemistry and physics of defects in solids, and their role in determining material properties. We would like to thank the International Advisory Committee for suggesting invited speakers, and the Local and Programme Committee for their hard work in planning and running the conference. Finally we would like to thank the authors and referees for their contributions to the proceedings. M L Alfredsson (Conference Chair) A V Chadwick R A Jackson E E McCabe

  15. Thermal characterization of QSH crashes in RFX-mod

    NASA Astrophysics Data System (ADS)

    Fassina, Alessandro; Gobbin, Marco; Franz, Paolo; Marrelli, Lionello; Ruzzon, Alberto

    2012-10-01

    QSH (Quasi Single Helicity) states have gained a growing interest in RFP research since they show improved confinement and transport features with respect to standard discharges. However, ITBs associated with QSH states can be obtained only in a transient way, and in general with a shorter lifetime with respect to that of the QSH phase [1]. In this work the analysis has essentially the purpose of confirming, with TS data, the Te dynamics seen with the double filter, multichord SXR spectrometer in [1]: TS data allow a better spatial definition of temperature profile and a more reliable description of plasma edge. Te profile features in rising and crashing phases are determined via ensemble averaging, possible precursors of thermal crashes are identified, while q(r) behavior is studied identifying the thermal structures associated with rational surfaces. [4pt] [1] Ruzzon et al, 39th EPS Conference, P2.023

  16. Controlled Folding, Motional, and Constitutional Dynamic Processes of Polyheterocyclic Molecular Strands.

    PubMed

    Barboiu, Mihail; Stadler, Adrian-Mihail; Lehn, Jean-Marie

    2016-03-18

    General design principles have been developed for the control of the structural features of polyheterocyclic strands and their effector-modulated shape changes. Induced defined molecular motions permit designed enforcement of helical as well as linear molecular shapes. The ability of such molecular strands to bind metal cations allows the generation of coiling/uncoiling processes between helically folded and extended linear states. Large molecular motions are produced on coordination of metal ions, which may be made reversible by competition with an ancillary complexing agent and fueled by sequential acid/base neutralization energy. The introduction of hydrazone units into the strands confers upon them constitutional dynamics, whereby interconversion between different strand compositions is achieved through component exchange. These features have relevance for nanomechanical devices. We present a morphological and functional analysis of such systems developed in our laboratories. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Wilderness Medicine Newsletter, Volume 9.

    ERIC Educational Resources Information Center

    Weber, Holly A., Ed.

    1998-01-01

    This document consists of the six issues of the "Wilderness Medicine Newsletter" published during 1998. The newsletter provides medical and rescue information for the non-physician in remote wilderness areas. Issues typically include feature articles, conference and training courses schedules, and personal narratives. Feature articles in…

  18. Fifth National Seismic Conference on Bridges & Highways : innovations in earthquake engineering for highway structures

    DOT National Transportation Integrated Search

    2007-02-01

    This document is the conference program of the 5th National Seismic Conference on Bridges and Highways. The conference was held in San Francisco on September 18-20, 2006 and attracted over 300 engineers, academician, and students from around the worl...

  19. Making Conferences Human Places of Learning

    ERIC Educational Resources Information Center

    Kenny, Michael

    2014-01-01

    Open Space Technology is a cumbersome name for a participative conference model that enables dynamic inclusive engagement and challenges traditional, highly structured hierarchical conference formats. Based on self-organising systems, (Wenger, 1998) Open Space Technology conferences have an open process, start with no agenda and empower the most…

  20. Ninth DOD/NASA/FAA Conference on Fibrous Composites in Structural Design, volume 1

    NASA Technical Reports Server (NTRS)

    Soderquist, Joseph R. (Compiler); Neri, Lawrence M. (Compiler); Bohon, Herman L. (Compiler)

    1992-01-01

    This publication contains the proceedings of the Ninth DOD/NASA/FAA conference on Fibrous Composites in structural Design. Presentations were made in the following areas of composite structural design: perspectives in composites; design methodology; design applications; design criteria; supporting technology; damage tolerance; and manufacturing.

  1. Chiral-selective nonlinear optical generation and emission control with plasmonic metamaterials (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Cai, Wenshan

    2016-09-01

    Metamaterials can be designed to exhibit extraordinarily strong chiral responses. Here we present a chiral metamaterial that produces both distinguishable linear and nonlinear features in the visible to near-infrared range. In additional to the gigantic chiral effects in the linear regime, the metamaterial demonstrates a pronounced contrast between second harmonic responses from the two circular polarizations. Linear and nonlinear images probed with circularly polarized lights show strongly defined contrast. Moreover, the chiral centers of the nanometallic structures with enhanced hotspots can be purposely opened for direct access, where emitters occupying the light-confining regions produce chiral-selective enhancement of two-photon luminescence.

  2. Microgravity Materials Science Conference 2000. Volume 1

    NASA Technical Reports Server (NTRS)

    Ramachandran, Narayanan (Editor); Bennett, Nancy (Editor); McCauley, Dannah (Editor); Murphy, Karen (Editor); Poindexter, Samantha (Editor)

    2001-01-01

    This is Volume 1 of 3 of the 2000 Microgravity Material Science Conference that was held June 6-8 at the Von Braun Center, Huntsville, Alabama. It was organized by the Microgravity Materials Science Discipline Working Group, sponsored by the Microgravity Research Division (MRD) at NASA Headquarters, and hosted by NASA Marshall Space Flight Center and the Alliance for Microgravity Materials Science and Applications (AMMSA). It was the fourth NASA conference of this type in the microgravity materials science discipline. The microgravity science program sponsored approx. 200 investigators, all of whom made oral or poster presentations at this conference. In addition, posters and exhibits covering NASA microgravity facilities, advanced technology development projects sponsored by the NASA Microgravity Research Division at NASA Headquarters, and commercial interests were exhibited. The purpose of the conference was to inform the materials science community of research opportunities in reduced gravity and to highlight the Spring 2001 release of the NASA Research Announcement (NRA) to solicit proposals for future investigations. It also served to review the current research and activities in materials science, to discuss the envisioned long-term goals. and to highlight new crosscutting research areas of particular interest to MRD. The conference was aimed at materials science researchers from academia, industry, and government. A workshop on in situ resource utilization (ISRU) was held in conjunction with the conference with the goal of evaluating and prioritizing processing issues in Lunar and Martian type environments. The workshop participation included invited speakers and investigators currently funded in the material science program under the Human Exploration and Development of Space (HEDS) initiative. The conference featured a plenary session every day with an invited speaker that was followed by three parallel breakout sessions in subdisciplines. Attendance was close to 350 people. Posters were available for viewing during the conference and a dedicated poster session was held on the second day. Nanotechnology radiation shielding materials, Space Station science opportunities, biomaterials research, and outreach and educational aspects of the program were featured in the plenary talks. This volume, the first to be released on CD-ROM for materials science, is comprised of the research reports submitted by the Principal Investigators at the conference.

  3. Microgravity Materials Science Conference 2000. Volume 3

    NASA Technical Reports Server (NTRS)

    Ramachandran, Narayanan; Bennett, Nancy; McCauley, Dannah; Murphy, Karen; Poindexter, Samantha

    2001-01-01

    This is Volume 3 of 3 of the 2000 Microgravity Materials Science Conference that was held June 6-8 at the Von Braun Center, Huntsville, Alabama. It was organized by the Microgravity Materials Science Discipline Working Group, sponsored by the Microgravity Research Division (MRD) at NASA Headquarters, and hosted by NASA Marshall Space Flight Center and the Alliance for Microgravity Materials Science and Applications (AMMSA). It was the fourth NASA conference of this type in the Microgravity materials science discipline. The microgravity science program sponsored 200 investigators, all of whom made oral or poster presentations at this conference- In addition, posters and exhibits covering NASA microgravity facilities, advanced technology development projects sponsored by the NASA Microgravity Research Division at NASA Headquarters, and commercial interests were exhibited. The purpose of the conference was to inform the materials science community of research opportunities in reduced gravity and to highlight the Spring 2001 release of the NASA Research Announcement (NRA) to solicit proposals for future investigations. It also served to review the current research and activities in material,, science, to discuss the envisioned long-term goals. and to highlight new crosscutting research areas of particular interest to MRD. The conference was aimed at materials science researchers from academia, industry, and government. A workshop on in situ resource utilization (ISRU) was held in conjunction with the conference with the goal of evaluating and prioritizing processing issues in Lunar and Martian type environments. The workshop participation included invited speakers and investigators currently funded in the material science program under the Human Exploration and Development of Space (HEDS) initiative. The conference featured a plenary session every day with an invited speaker that was followed by three parallel breakout sessions in subdisciplines. Attendance was close to 350 people, Posters were available for viewing during the conference and a dedicated poster session was held on the second day. Nanotechnology, radiation shielding materials, Space Station science opportunities, biomaterials research, and outreach and educational aspects of the program were featured in the plenary talks. This volume, the first to be released on CD-ROM for materials science, is comprised of the research reports submitted by the Principal Investigators at the conference.

  4. Microgravity Materials Science Conference 2000. Volume 2

    NASA Technical Reports Server (NTRS)

    Ramachandran, Narayanan (Editor); Bennett, Nancy (Editor); McCauley, Dannah (Editor); Murphy, Karen (Editor); Poindexter, Samantha (Editor)

    2001-01-01

    This is Volume 2 of 3 of the 2000 Microgravity Materials Science Conference that was held June 6-8 at the Von Braun Center, Huntsville, Alabama. It was organized by the Microgravity Materials Science Discipline Working Group, sponsored by the Microgravity Research Division (MRD) at NASA Headquarters, and hosted by NASA Marshall Space Flight Center and the Alliance for Microgravity Materials Science and Applications (AMMSA). It was the fourth NASA conference of this type in the Microgravity materials science discipline. The microgravity science program sponsored approx. 200 investigators, all of whom made oral or poster presentations at this conference- In addition, posters and exhibits covering NASA microgravity facilities, advanced technology development projects sponsored by the NASA Microgravity Research Division at NASA Headquarters, and commercial interests were exhibited. The purpose of the conference %%,its to inform the materials science community of research opportunities in reduced gravity and to highlight the Spring 2001 release of the NASA Research Announcement (NRA) to solicit proposals for future investigations. It also served to review the current research and activities in material,, science, to discuss the envisioned long-term goals. and to highlight new crosscutting research areas of particular interest to MRD. The conference was aimed at materials science researchers from academia, industry, and government. A workshop on in situ resource utilization (ISRU) was held in conjunction with the conference with the goal of evaluating and prioritizing processing issues in Lunar and Martian type environments. The workshop participation included invited speakers and investigators currently funded in the material science program under the Human Exploration and Development of Space (HEDS) initiative. The conference featured a plenary session every day with an invited speaker that was followed by three parallel breakout sessions in subdisciplines. Attendance was close to 350 people, Posters were available for viewing during the conference and a dedicated poster session was held on the second day. Nanotechnology, radiation shielding materials, Space Station science opportunities, biomaterials research, and outreach and educational aspects of the program were featured in the plenary talks. This volume, the first to be released on CD-ROM for materials science, is comprised of the research reports submitted by the Principal Investigators at the conference.

  5. Optimization method of superpixel analysis for multi-contrast Jones matrix tomography (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Miyazawa, Arata; Hong, Young-Joo; Makita, Shuichi; Kasaragod, Deepa K.; Miura, Masahiro; Yasuno, Yoshiaki

    2017-02-01

    Local statistics are widely utilized for quantification and image processing of OCT. For example, local mean is used to reduce speckle, local variation of polarization state (degree-of-polarization-uniformity (DOPU)) is used to visualize melanin. Conventionally, these statistics are calculated in a rectangle kernel whose size is uniform over the image. However, the fixed size and shape of the kernel result in a tradeoff between image sharpness and statistical accuracy. Superpixel is a cluster of pixels which is generated by grouping image pixels based on the spatial proximity and similarity of signal values. Superpixels have variant size and flexible shapes which preserve the tissue structure. Here we demonstrate a new superpixel method which is tailored for multifunctional Jones matrix OCT (JM-OCT). This new method forms the superpixels by clustering image pixels in a 6-dimensional (6-D) feature space (spatial two dimensions and four dimensions of optical features). All image pixels were clustered based on their spatial proximity and optical feature similarity. The optical features are scattering, OCT-A, birefringence and DOPU. The method is applied to retinal OCT. Generated superpixels preserve the tissue structures such as retinal layers, sclera, vessels, and retinal pigment epithelium. Hence, superpixel can be utilized as a local statistics kernel which would be more suitable than a uniform rectangle kernel. Superpixelized image also can be used for further image processing and analysis. Since it reduces the number of pixels to be analyzed, it reduce the computational cost of such image processing.

  6. EDITORIAL: Adaptive and active materials: Selected papers from the ASME 2010 Conference on Smart Materials, Adaptive Structures and Intelligent Systems (SMASIS 10) (Philadelphia, PA, USA, 28 September-1 October 2010) Adaptive and active materials: Selected papers from the ASME 2010 Conference on Smart Materials, Adaptive Structures and Intelligent Systems (SMASIS 10) (Philadelphia, PA, USA, 28 September-1 October 2010)

    NASA Astrophysics Data System (ADS)

    Brei, Diann

    2011-09-01

    The third annual meeting of the AMSE/AIAA Smart Materials, Adaptive Structures and Intelligent Systems Conference (SMASIS) took place in the heart of historic Philadelphia's cultural district, and included a pioneer banquet in the National Constitutional Center. The applications emphasis of the 2010 conference was reflected in keynote talks by Dr Alan Taub, vice president of General Motors global research and development, 'Smart materials in the automotive industry'; Dr Charles R Farrar, engineering institute leader at Los Alamos National Laboratory, 'Future directions for structural health monitoring of civil engineering infrastructure'; and Professor Christopher S Lynch of the University of California Los Angeles, 'Ferroelectric materials and their applications'. The SMASIS conference was divided into six technical symposia each of which included basic research, applied technological design and development, and industrial and governmental integrated system and application demonstrations. The six symposia were: SYMP 1 Multifunctional Materials; SYMP 2 Active Materials, Mechanics and Behavior; SYMP 3 Modeling, Simulation and Control; SYMP 4 Enabling Technologies and Integrated System Design; SYMP 5 Structural Health Monitoring/NDE; and SYMP 6 Bio-inspired Smart Materials and Structures. In addition, the conference introduced a new student and young professional development symposium. Authors of papers in the materials areas (symposia 1, 2 and 6) were invited to write a full journal article on their presentation topic for publication in this special issue of Smart Materials and Structures. This set of papers demonstrates the exceptional quality and originality of the conference presentations. We are appreciative of their efforts in producing this collection of highly relevant articles on smart materials.

  7. Cooperative Collection Development in Multitype Library Networks: A Beginning--Goals and Methods. Proceedings of the Annual Conference of the Missouri Library Association (1980).

    ERIC Educational Resources Information Center

    Tompkins, Philip, Ed.

    This document presents the proceedings of a conference organized to review the cooperative collection development features of the Missouri State Network Plan and to outline specific goals, methods, and materials for facilitating cooperative collection development projects in the state's multitype library networks. An introduction provides…

  8. Proceedings of the International Conference on Educational Data Mining (EDM) (6th, Memphis, TN., USA, July 6-9, 2013)

    ERIC Educational Resources Information Center

    D'Mello, S. K., Ed.; Calvo, R. A., Ed.; Olney, A., Ed.

    2013-01-01

    Since its inception in 2008, the Educational Data Mining (EDM) conference series has featured some of the most innovative and fascinating basic and applied research centered on data mining, education, and learning technologies. This tradition of exemplary interdisciplinary research has been kept alive in 2013 as evident through an imaginative,…

  9. News Conference Features with Next Space Station Crew

    NASA Image and Video Library

    2017-12-07

    A NASA news conference was held Dec. 7 at Johnson Space Center in Houston with the next crew launching to the International Space Station. NASA astronauts A.J. (Drew) Feustel, Ricky Arnold, and Oleg Artemyev of the Russian space agency Roscosmos will launch to the space station aboard a Soyuz MS-08 spacecraft in March 2018, from the Baikonur Cosmodrome in Kazakhstan.

  10. 2012 Gordon Research Conference, Electron donor-acceptor interactions, August 5-10 2012

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McCusker, James

    The upcoming incarnation of the Gordon Research Conference on Electron Donor Acceptor Interactions will feature sessions on classic topics including proton-coupled electron transfer, dye-sensitized solar cells, and biological electron transfer, as well as emerging areas such as quantum coherence effects in donor-acceptor interactions, spintronics, and the application of donor-acceptor interactions in chemical synthesis.

  11. Design principles of hair-like structures as biological machines

    PubMed Central

    2018-01-01

    Hair-like structures are prevalent throughout biology and frequently act to sense or alter interactions with an organism's environment. The overall shape of a hair is simple: a long, filamentous object that protrudes from the surface of an organism. This basic design, however, can confer a wide range of functions, owing largely to the flexibility and large surface area that it usually possesses. From this simple structural basis, small changes in geometry, such as diameter, curvature and inter-hair spacing, can have considerable effects on mechanical properties, allowing functions such as mechanosensing, attachment, movement and protection. Here, we explore how passive features of hair-like structures, both individually and within arrays, enable diverse functions across biology. Understanding the relationships between form and function can provide biologists with an appreciation for the constraints and possibilities on hair-like structures. Additionally, such structures have already been used in biomimetic engineering with applications in sensing, water capture and adhesion. By examining hairs as a functional mechanical unit, geometry and arrangement can be rationally designed to generate new engineering devices and ideas. PMID:29848593

  12. Chromatin structure of the LCR in the human β-globin locus transcribing the adult δ- and β-globin genes.

    PubMed

    Kim, Seoyeon; Kim, Yea Woon; Shim, Sung Han; Kim, Chul Geun; Kim, Aeri

    2012-03-01

    The β-like globin genes are transcribed in a developmental stage specific fashion in erythroid cells. The specific transcription of globin genes is conferred by the locus control region (LCR), but the chromatin structure of the LCR in the human adult β-globin locus transcribing the δ- and β-globin genes is not clear. Here, we employed hybrid MEL cells that contain a human chromosome 11. The δ- and β-globin genes were highly transcribed in hybrid MEL/ch11 cells after transcriptional induction. LCR HS3 and HS2 were strongly occupied by erythroid specific transcriptional activators and co-factors in the induced locus. These HSs, but not HS4 and HS1, were in close proximity with the active globin genes as revealed by high resolution 3C experiments. The active features at HS3 were markedly established after transcriptional induction, while HS2 was in a relatively active conformation before the induction. Unexpectedly, HS1 did not show notable active features except histone hyperacetylation. Taken together, the LCR of the human β-globin locus transcribing the adult δ- and β-globin genes has HS specific chromatin structure. The structure at each HS, which is different from the locus transcribing the fetal globin genes, might relate to its role in transcribing the adult genes. Copyright © 2011 Elsevier Ltd. All rights reserved.

  13. The Third Annual NASA Science Internet User Working Group Conference

    NASA Technical Reports Server (NTRS)

    Lev, Brian S. (Editor); Gary, J. Patrick (Editor)

    1993-01-01

    The NASA Science Internet (NSI) User Support Office (USO) sponsored the Third Annual NSI User Working Group (NSIUWG) Conference March 30 through April 3, 1992, in Greenbelt, MD. Approximately 130 NSI users attended to learn more about the NSI, hear from projects which use NSI, and receive updates about new networking technologies and services. This report contains material relevant to the conference; copies of the agenda, meeting summaries, presentations, and descriptions of exhibitors. Plenary sessions featured a variety of speakers, including NSI project management, scientists, and NSI user project managers whose projects and applications effectively use NSI, and notable citizens of the larger Internet community. The conference also included exhibits of advanced networking applications; tutorials on internetworking, computer security, and networking technologies; and user subgroup meetings on the future direction of the conference, networking, and user services and applications.

  14. Research in Structures, Structural Dynamics and Materials, 1990

    NASA Technical Reports Server (NTRS)

    Barthelemy, Jean-Francois M. (Compiler); Noor, Ahmed K. (Compiler)

    1990-01-01

    The Structural Dynamics and Materials (SDM) Conference was held on April 2 to 4, 1990 in Long Beach, California. This publication is a compilation of presentations of the work-in-progress sessions and does not contain papers from the regular sessions since those papers are published by AIAA in the conference proceedings.

  15. Mitosis detection using generic features and an ensemble of cascade adaboosts.

    PubMed

    Tek, F Boray

    2013-01-01

    Mitosis count is one of the factors that pathologists use to assess the risk of metastasis and survival of the patients, which are affected by the breast cancer. We investigate an application of a set of generic features and an ensemble of cascade adaboosts to the automated mitosis detection. Calculation of the features rely minimally on object-level descriptions and thus require minimal segmentation. The proposed work was developed and tested on International Conference on Pattern Recognition (ICPR) 2012 mitosis detection contest data. We plotted receiver operating characteristics curves of true positive versus false positive rates; calculated recall, precision, F-measure, and region overlap ratio measures. WE TESTED OUR FEATURES WITH TWO DIFFERENT CLASSIFIER CONFIGURATIONS: 1) An ensemble of single adaboosts, 2) an ensemble of cascade adaboosts. On the ICPR 2012 mitosis detection contest evaluation, the cascade ensemble scored 54, 62.7, and 58, whereas the non-cascade version scored 68, 28.1, and 39.7 for the recall, precision, and F-measure measures, respectively. Mostly used features in the adaboost classifier rules were a shape-based feature, which counted granularity and a color-based feature, which relied on Red, Green, and Blue channel statistics. The features, which express the granular structure and color variations, are found useful for mitosis detection. The ensemble of adaboosts performs better than the individual adaboost classifiers. Moreover, the ensemble of cascaded adaboosts was better than the ensemble of single adaboosts for mitosis detection.

  16. PREFACE: International Conference on Structural Nano Composites (NANOSTRUC 2012)

    NASA Astrophysics Data System (ADS)

    Njuguna, James

    2012-09-01

    Dear Colleagues It is a great pleasure to welcome you to NanoStruc2012 at Cranfield University. The purpose of the 2012 International Conference on Structural Nano Composites (NanoStruc2012) is to promote activities in various areas of materials and structures by providing a forum for exchange of ideas, presentation of technical achievements and discussion of future directions. NanoStruc brings together an international community of experts to discuss the state-of-the-art, new research results, perspectives of future developments, and innovative applications relevant to structural materials, engineering structures, nanocomposites, modelling and simulations, and their related application areas. The conference is split in 7 panel sessions, Metallic Nanocomposites and Coatings, Silica based Nanocomposites, safty of Nanomaterials, Carboin based Nanocomposites, Multscale Modelling, Bio materials and Application of Nanomaterials. All accepted Papers will be published in the IOP Conference Series: Materials Science and Engineering (MSE), and included in the NanoStruc online digital library. The abstracts will be indexed in Scopus, Compedex, Inspec, INIS (International Nuclear Information System), Chemical Abstracts, NASA Astrophysics Data System and Polymer Library. Before ending this message, I would like to acknowledge the hard work, professional skills and efficiency of the team which ensured the general organisation. As a conclusion, I would like to Welcome you to the Nanostruc2012 and wish you a stimulating Conference and a wonderful time. On behalf of the scientific committee, Signature James Njuguna Conference Chair The PDF of this preface also contains committee listings and associates logos.

  17. An international conference in honour of the centennial of the birth of Ya.B. Zeldovich, "Subatomic Particles, Nucleons, Atoms, the Universe: Processes and Structure"

    NASA Astrophysics Data System (ADS)

    Kilin, S. Ya.; Ruffini, R.; Vereshchagin, G.

    2015-06-01

    An international conference in honour of the centennial of the birth of Ya.B. Zeldovich, "Subatomic Particles, Nucleons, Atoms, the Universe: Processes and Structure" was held in Minsk, Belarus on March 10-14, 2014. Scientific papers based on plenary presentations made at this conference are being published in Volumes 6 and 7, 2015 of "Astronomy Reports."

  18. PIALA 2004: Maron In Read Im Jeje Ej Ad Kojatdikdik, Library Ko Rej Jikin Kakurmool Kojatdikdik In Im Jolet Eo Ad Ej Bwinnid--Literacy Our Hope, Libraries Our Scope and Heritage Our Property (14th, Majuro Atoll, Marshall Islands, November 16-19, 2004) and PIALA 2005: Kasrpacsr Misenge Ac Etwack Lutu--Resources Today and Learning Tomorrow (15th, Tofol, Kosrae, Federated States of Micronesia, November 8-10, 2005). Selected Papers from the Pacific Islands Association of Libraries and Archives Annual Conferences

    ERIC Educational Resources Information Center

    Cohen, Arlene, Ed.

    2006-01-01

    This publication follows the tradition of publishing selected papers from PIALA annual conferences, however, for the first time, two PIALA conferences (PIALA 2004 and PIALA 2005) are published in one volume, containing papers from both events. Both conferences featured papers by local Micronesian and Pacific Islands experts, as well as presenters…

  19. The 22nd International Conference on Optical Fibre Sensors, OFS-22

    NASA Astrophysics Data System (ADS)

    Liao, Yianbiao; Jin, Wei; Jones, Julian; Tatam, Ralph

    2013-09-01

    In October 2013, the 22nd International Conference on Optical Fibre Sensors was held in Beijing, attracting about 500 participants with 417 presentations. The conference began in 1983 in London, and in the subsequent 30 years has defined the subject. The conference is held approximately every 18 months, and rotates between three world regions: Asia/Pacific, Europe and the Americas. The conference is not 'owned' by any learned society or professional institution, but is organized by a self-sustaining international steering committee. This special feature represents the sixth occasion on which Measurement Science and Technology has published papers based on a development of a cross-section of work presented at the conference. The subject of optical fibre sensors has its beginnings in the enabling technologies of the optical fibre itself and the development of laser technologies suitable for practical use in demanding real-world applications. But the real driver for the subject in its early years was in the development of systems for defence applications, most notably for strategic-grade sea-bed hydrophone arrays for submarine detection, and the optical fibre gyroscope (the community has recently celebrated the 35th anniversary of its earliest publication) for aerospace navigation. Both applications continue to be important, but now with extensive civil applications: hydrophones for oil exploration and reservoir monitoring and management, and fibre gyroscopes for applications ranging from those requiring low cost and mass production (such as industrial robots and in agricultural machinery) to the most exotic and highest performance for space applications. The articles in this special feature exemplify the principal themes of the subject: enabling technologies, application-specific developments and systems considerations. In recent years, perhaps the most important—indeed, dominant—enabling technologies have been based on structuring of fibres: longitudinally, as in Bragg gratings, or transversely, using the science of metamaterials to produce microstructured fibres (e.g. photonic crystal fibres). In-fibre gratings continue to provide new types of sensor based on wavelength encoding, or for wavelength control for specialized sources or detection techniques. Microstructured fibres, meanwhile, provide materials with dispersion characteristics unattainable with conventional materials, as well as otherwise unfeasible physical characteristics that can be tailored to specific sensing applications. Examples of these types of technologies can be found in the following articles. The fields of application of optical fibre sensors, even if restricted to those presented at the conference, would be too lengthy to enumerate here. However, in this issue there are examples from medicine, transport, chemical sensing and electric power distribution, amongst others. An important advantage conferred by optical fibre sensors is the ability with which they can be multiplexed to form large arrays, interrogated via a single fibre, a topic that forms the subject of a number of papers in the issue. Lastly, as fibre sensors become the technology of choice in widespread applications, the issue of formal measurement standards begins to become important, and it is evidence of the maturity of the field that the subject is addressed in one of the papers published here: optical fibre sensors can now surely be said to have progressed from the physics laboratory to become a mainstream engineering reality.

  20. The Role of Technology: Theme Group 3. Proceedings of the International Congress on Mathematical Education (5th, Adelaide, South Australia, August 24-30, 1984).

    ERIC Educational Resources Information Center

    Mohyla, Jury, Ed.

    This conference report bears witness to the centrality and growing significance of the debate on the impact of technology on mathematics education. It presents an overview of the conference's Technology Theme group's work, featuring summaries of the reports of 17 constituent working groups under 6 major headings: (1) "Challenges to the…

  1. LEADERSHIP FOR VOCATIONAL EDUCATION IN CALIFORNIA--THEORY AND PRACTICE OF PROGRAM DEVELOPMENT, SUMMARY REPORT OF THE COASTAL, CENTRAL, AND SOUTHERN REGIONAL CONFERENCES (JANUARY-FEBRUARY, 1966).

    ERIC Educational Resources Information Center

    California State Dept. of Education, Sacramento. Vocational Education Services.

    APPROXIMATELY 100 SUPERVISORS AND COORDINATORS OF PUBLIC SCHOOL VOCATIONAL EDUCATION PROGRAMS IN CALIFORNIA PARTICIPATED IN TWO CONFERENCES TO CONSIDER THE METHODS OF LABOR FORCE ENUMERATION, THE ASPECTS OF THE LABOR SITUATION MOST PERTINENT TO CHANGES IN VOCATIONAL EDUCATION, THE PROBLEMS OF WORKING WITH MANPOWER DATA, AND THE SALIENT FEATURES OF…

  2. Program Bytes - Satellite Meetings, SIGs, and AKEs at ISMB 2016

    PubMed Central

    Fogg, Christiana

    2016-01-01

    The International Society for Computational Biology (ISCB) is gearing up for its flagship meeting, ISMB.  The conference is the world’s largest gathering of computational biology and bioinformatics researchers. The ISMB 2016 pre-conference program will feature 17 special interest group and satellite meetings over the course of two days. This article previews those special meetings at ISCB’s flagship meeting, ISMB. PMID:27347388

  3. Hands That Shape the World: Report on the Conditions of Immigrant Women in the U.S. Five Years after the Beijing Conference.

    ERIC Educational Resources Information Center

    National Network for Immigrant and Refugee Rights, Oakland, CA.

    This report details the challenges that immigrant women in the United States have faced since the 1995 United Nations World Conference on Women in Beijing, China. It presents a compilation of research and synthesis by immigrants' rights activists and organizations. Data come from immigrant women's testimony. The following topics are featured:…

  4. Broadening Participation in Science, Technology and Medicine: Proceedings of the Annual Technological Literacy Conference (6th, Washington, D.C., February 1-3, 1991).

    ERIC Educational Resources Information Center

    Cheek, Dennis W., Ed.

    This document contains the text of 50 papers presented at a national conference that focused on the relationships among science, technology, and society (STS). Most of the papers presented featured one of five major thematic areas around which the National Association for Science, Technology and Society is organized: education and information;…

  5. Proceedings of the Annual Meeting of the International Group for the Psychology of Mathematics Education (PME) (28th, Bergen, Norway, July 14-18, 2004). Volume 2

    ERIC Educational Resources Information Center

    Hoines, Marit Johnsen, Ed.; ; Fuglestad, Anne Berit, Ed.

    2004-01-01

    This document contains the second volume of the proceedings of the 28th annual conference of the International Group for the Psychology of Mathematics Education. Conference presentations are centered around the theme "Inclusion and Diversity". This volume features 65 research report papers: (1) Constructing Meanings and Utilities within Algebraic…

  6. Ninth DOD/NASA/FAA Conference on Fibrous Composites in Structural Design, volume 2

    NASA Technical Reports Server (NTRS)

    Soderquist, Joseph R. (Compiler); Neri, Lawrence M. (Compiler); Bohon, Herman L. (Compiler)

    1992-01-01

    This publication contains the proceedings of the Ninth DOD/NASA/FAA Conference on Fibrous Composites in Structural Design held at Lake Tahoe, Nevada, during 4-7 Nov. 1991. Presentations were made in the following areas of composite structural design: perspectives in composites, design methodology, design applications, design criteria, supporting technology, damage tolerance, and manufacturing.

  7. Ninth DOD/NASA/FAA Conference on Fibrous Composites in Structural Design, volume 3

    NASA Technical Reports Server (NTRS)

    Soderquist, Joseph R. (Compiler); Neri, Lawrence M. (Compiler); Bohon, Herman L. (Compiler)

    1992-01-01

    This publication contains the proceedings of the Ninth DOD/NASA/FAA Conference on Fibrous Composites in Structural Design held at Lake Tahoe, Nevada, during 4-7 Nov. 1991. Presentations were made in the following areas of composite structural design: perspectives in composites, design methodology, design applications, design criteria, supporting technology, damage tolerance, and manufacturing.

  8. Proceedings of the Fourth Microgravity Fluid Physics and Transport Phenomena Conference

    NASA Technical Reports Server (NTRS)

    Singh, Bhim S. (Editor)

    1999-01-01

    This conference presents information to the scientific community on research results, future directions, and research opportunities in microgravity fluid physics and transport phenomena within NASA's microgravity research program. The conference theme is "The International Space Station." Plenary sessions provide an overview of the Microgravity Fluid Physics Program, the International Space Station and the opportunities ISS presents to fluid physics and transport phenomena researchers, and the process by which researchers may become involved in NASA's program, including information about the NASA Research Announcement in this area. Two plenary lectures present promising areas of research in electrohydrodynamics/electrokinetics in the movement of particles and in micro- and meso-scale effects on macroscopic fluid dynamics. Featured speakers in plenary sessions present results of recent flight experiments not heretofore presented. The conference publication consists of this book of abstracts and the full Proceedings of the 4th Microgravity Fluid Physics and Transport Phenomena Conference on CD-ROM, containing full papers presented at the conference (NASA/CP-1999-208526/SUPPL1).

  9. International conference on "Photosynthesis research for sustainability-2015" in honor of George C. Papageorgiou", September 21-26, 2015, Crete, Greece.

    PubMed

    Allakhverdiev, Suleyman I; Tomo, Tatsuya; Stamatakis, Kostas; Govindjee

    2016-12-01

    During September 21-26, 2015, an international conference entitled ''Photosynthesis Research for Sustainability-2015'' was held in honor of George C. Papageorgiou at the Conference Center of the Orthodox Academy of Crete, an exceptionally beautiful location right on the Mediterranean Sea coast, Kolymvari, Chania, Crete, (Greece) (see http://photosynthesis2015.cellreg.org/ ). The meeting was held under the auspices of the Greek "General Secretariat for Research and Technology" (GSRT). We first provide a brief introduction and key contributions of George C. Papageorgiou, the honored scientist, and then information on the conference, on the speakers, and the program. A special feature of this conference was awards given to 13 young investigators, who are recognized in this Report. Several photographs are also included; they show the pleasant ambience at this conference. We invite the readers to the next conference on "Photosynthesis Research for Sustainability-2016," which will honor Nathan Nelson and T. Nejat Veziroglu; it will be held during June 19-25, 2016, in Pushchino, Moscow Region, Russia (see http://photosynthesis2016.cellreg.org/ ).

  10. Venus - Three-Dimensional Perspective View of Alpha Regio

    NASA Technical Reports Server (NTRS)

    1992-01-01

    A portion of Alpha Regio is displayed in this three-dimensional perspective view of the surface of Venus. Alpha Regio, a topographic upland approximately 1300 kilometers across, is centered on 25 degrees south latitude, 4 degrees east longitude. In 1963, Alpha Regio was the first feature on Venus to be identified from Earth-based radar. The radar-bright area of Alpha Regio is characterized by multiple sets of intersecting trends of structural features such as ridges, troughs, and flat-floored fault valleys that, together, form a polygonal outline. Directly south of the complex ridged terrain is a large ovoid-shaped feature named Eve. The radar-bright spot located centrally within Eve marks the location of the prime meridian of Venus. Magellan synthetic aperture radar data is combined with radar altimetry to develop a three-dimensional map of the surface. Ray tracing is used to generate a perspective view from this map. The vertical scale is exaggerated approximately 23 times. Simulated color and a digital elevation map developed by the U. S. Geological Survey are used to enhance small scale structure. The simulated hues are based on color images recorded by the Soviet Venera 13 and 14 spacecraft. The image was produced at the JPL Multimission Image Processing Laboratory by Eric De Jong, Jeff Hall, and Myche McAuley, and is a single frame from the movie released at the March 5, 1991, press conference.

  11. Constitutively active mutants of the alpha 1B-adrenergic receptor: role of highly conserved polar amino acids in receptor activation.

    PubMed Central

    Scheer, A; Fanelli, F; Costa, T; De Benedetti, P G; Cotecchia, S

    1996-01-01

    Site-directed mutagenesis and molecular dynamics simulations of the alpha 1B-adrenergic receptor (AR) were combined to explore the potential molecular changes correlated with the transition from R (inactive state) to R (active state). Using molecular dynamics analysis we compared the structural/dynamic features of constitutively active mutants with those of the wild type and of an inactive alpha 1B-AR to build a theoretical model which defines the essential features of R and R. The results of site-directed mutagenesis were in striking agreement with the predictions of the model supporting the following hypothesis. (i) The equilibrium between R and R depends on the equilibrium between the deprotonated and protonated forms, respectively, of D142 of the DRY motif. In fact, replacement of D142 with alanine confers high constitutive activity to the alpha 1B-AR. (ii) The shift of R143 of the DRY sequence out of a conserved 'polar pocket' formed by N63, D91, N344 and Y348 is a feature common to all the active structures, suggesting that the role of R143 is fundamental for mediating receptor activation. Disruption of these intramolecular interactions by replacing N63 with alanine constitutively activates the alpha 1B-AR. Our findings might provide interesting generalities about the activation process of G protein-coupled receptors. Images PMID:8670860

  12. Intraoperative Consultation and Macroscopic Handling: The International Society of Urological Pathology (ISUP) Testicular Cancer Consultation Conference Recommendations.

    PubMed

    Verrill, Clare; Perry-Keene, Joanna; Srigley, John R; Zhou, Ming; Humphrey, Peter A; Lopez-Beltran, Antonio; Egevad, Lars; Ulbright, Thomas M; Tickoo, Satish K; Epstein, Jonathan I; Compérat, Eva; Berney, Daniel M

    2018-06-01

    The International Society of Urological Pathology held a conference on issues in testicular and penile pathology in Boston in March 2015, which included a presentation by the testis macroscopic features working group. The presentation focused on current published guidance for macroscopic handling of testicular tumors and retroperitoneal lymph node dissections with a summary of results from an online survey of members preceding the conference. The survey results were used to initiate discussions, but decisions on practice were made by expert consensus rather than voting. The importance of comprehensive assessment at the time of gross dissection with confirmation of findings by microscopic assessment was underscored. For example, the anatomic landmarks denoting the distinction of hilar soft tissue invasion (pT2) from spermatic cord invasion (pT3 category) can only be determined by careful macroscopic assessment in many cases. Other recommendations were to routinely sample epididymis, rete testis, hilar soft tissue, and tunica vaginalis in order to confirm macroscopic invasion of these structures or if not macroscopically evident, to exclude subtle microscopic invasion. Tumors 2 cm or less in greatest dimension should be completely embedded. If the tumor is >2 cm in greatest dimension, 10 blocks or a minimum of 1 to 2 additional blocks per centimeter should be taken (whichever is greater).

  13. Structural features of influenza A virus panhandle RNA enabling the activation of RIG-I independently of 5′-triphosphate

    PubMed Central

    Lee, Mi-Kyung; Kim, Hee-Eun; Park, Eun-Byeol; Lee, Janghyun; Kim, Ki-Hun; Lim, Kyungeun; Yum, Seoyun; Lee, Young-Hoon; Kang, Suk-Jo; Lee, Joon-Hwa; Choi, Byong-Seok

    2016-01-01

    Retinoic acid-inducible gene I (RIG-I) recognizes specific molecular patterns of viral RNAs for inducing type I interferon. The C-terminal domain (CTD) of RIG-I binds to double-stranded RNA (dsRNA) with the 5′-triphosphate (5′-PPP), which induces a conformational change in RIG-I to an active form. It has been suggested that RIG-I detects infection of influenza A virus by recognizing the 5′-triphosphorylated panhandle structure of the viral RNA genome. Influenza panhandle RNA has a unique structure with a sharp helical bending. In spite of extensive studies of how viral RNAs activate RIG-I, whether the structural elements of the influenza panhandle RNA confer the ability to activate RIG-I signaling has been poorly explored. Here, we investigated the dynamics of the influenza panhandle RNA in complex with RIG-I CTD using NMR spectroscopy and showed that the bending structure of the panhandle RNA negates the requirement of a 5′-PPP moiety for RIG-I activation. PMID:27288441

  14. Proceedings of the NASA/DOD Control/Structures Interaction Technology Conference (4th) Held in Orlando, Florida on 5-7 November 1990

    DTIC Science & Technology

    1991-01-15

    Orlando, Florida, 5-7 November 1990. The conference was cosponsored by the Wright Laboratory and the NASA Langley Research Center. The Conference...Subiect Terms. Keywords or phrases responsible for writing the report, performing identifying major subjects in the repc.,t. the research , or...Laboratory and the NASA Langley Research Center have agreed to sponsor alternately a series of annual control/structures interaction technology

  15. Epigenetics, eh! A meeting summary of the Canadian Conference on Epigenetics.

    PubMed

    Rodenhiser, David I; Bérubé, Nathalie G; Mann, Mellissa R W

    2011-10-01

    In May 2011, the Canadian Conference on Epigenetics: Epigenetics Eh! was held in London, Canada. The objectives of this conference were to showcase the breadth of epigenetic research on environment and health across Canada and to provide the catalyst to develop collaborative Canadian epigenetic research opportunities, similar to existing international epigenetic initiatives in the US and Europe. With ten platform sessions and two sessions with over 100 poster presentations, this conference featured cutting-edge epigenetic research, presented by Canadian and international principal investigators and their trainees in the field of epigenetics and chromatin dynamics. An EpigenART competition included ten artists, creating a unique opportunity for artists and scientists to interact and explore their individual interpretations of this scientific discipline. The conference provided a unique venue for a significant cross-section of Canadian epigenetic researchers from diverse disciplines to meet, interact, collaborate and strategize at the national level.

  16. Feature Article: Fast scanning tunnelling microscopy as a tool to understand changes on metal surfaces: from nanostructures to single atoms

    NASA Astrophysics Data System (ADS)

    Morgenstern, Karina

    2005-03-01

    The Feature Article [1] describes how structural changes in metallic nanostructures can be followed with fast scanning tunneling microscopy (STM). The title page shows the same spot of a Ag(111) surface at room temperature, imaged with STM approximately one hour apart. Intrinsic changes to prepared nano-structures are marked as Brownian motion of vacancy islands (rectangle), coalescence of two vacancy islands (hexagon), and decay of an adatom island (circle).Karina Morgenstern is now professor at the University of Hannover. Her research is placed within the field of nanoscience and is in particular devoted to thermally activated processes of metallic nanostructures, electronically activated reactions of molecules on metallic surfaces, and water-metal interactions.The present issue of physica status solidi (b) also contains the article Apperance of copper d9 defect centres in wide-gap CdSe nanoparticles: A high-fequency EPR study by N. R. J. Poolton et al. as Editor's Choice [2] as well as several papers on electrical and nonlinear optical properties from the European Conference on Organised Films (ECOF 2004) chaired by José Antonio de Saja, Valladolid.

  17. Voltage Sensing in Membranes: From Macroscopic Currents to Molecular Motions

    PubMed Central

    Freites, J. Alfredo; Tobias, Douglas J.

    2015-01-01

    Voltage-sensing domains (VSDs) are integral membrane protein units that sense changes in membrane electric potential, and through the resulting conformational changes, regulate a specific function. VSDs confer voltage-sensitivity to a large superfamily of membrane proteins that includes voltage-gated Na+, K+, Ca2+, and H+ selective channels, hyperpolarization-activated cyclic nucleotide-gated channels, and voltage-sensing phosphatases. VSDs consist of four transmembrane segments (termed S1 through S4). Their most salient structural feature is the highly conserved positions for charged residues in their sequences. S4 exhibits at least three conserved triplet repeats composed of one basic residue (mostly arginine) followed by two hydrophobic residues. These S4 basic side chains participate in a state-dependent internal salt-bridge network with at least four acidic residues in S1–S3. The signature of voltage-dependent activation in electrophysiology experiments is a transient current (termed gating or sensing current) upon a change in applied membrane potential as the basic side chains in S4 move across the membrane electric field. Thus, the unique structural features of the VSD architecture allow for competing requirements: maintaining a series of stable transmembrane conformations, while allowing charge motion, as briefly reviewed here. PMID:25972106

  18. Origami-based mechanical metamaterials with tunable frequency band structures (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Yasuda, Hiromi; Pratt, Riley; Yang, Jinkyu

    2017-04-01

    We investigate wave dynamics in origami-based mechanical metamaterials composed of bellows-like origami structures, specifically the Tachi-Miura Polyhedron (TMP). One of the unique features of the TMP is that its structural deformations take place only along the crease lines, therefore the structure can be made of rigid plates and hinges. By utilizing this feature, we introduce linear torsional springs to model the crease lines and derive the force and displacement relationship of the TMP structure along the longitudinal direction. Our analysis shows strain softening/hardening behaviors in compression/tensile regions respectively, and the force-displacement curve can be manipulated by altering the initial configuration of the TMP (e.g., the initial folding angle). We also fabricate physical prototypes and measure the force-displacement behavior to verify our analytical model. Based on this static analysis on the TMP, we simplify the TMP structure into a linkage model, preserving the tunable strain softening/hardening behaviors. Dynamic analysis is also conducted numerically to analyze the frequency response of the simplified TMP unit cell under harmonic excitations. The simplified TMP exhibits a transition between linear and nonlinear behaviors, which depends on the amplitude of the excitation and the initial configuration. In addition, we design a 1D system composed of simplified TMP unit cells and analyze the relationship between frequency and wave number. If two different configurations of the unit cell (e.g., different initial folding angles) are connected in an alternating arrangement, the system develops frequency bandgaps. These unique static/dynamic behaviors can be exploited to design engineering devices which can handle vibrations and impact in an efficient manner.

  19. Multimodal, 3D pathology-mimicking bladder phantom for evaluation of cystoscopic technologies (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Smith, Gennifer T.; Lurie, Kristen L.; Zlatev, Dimitar V.; Liao, Joseph C.; Ellerbee, Audrey K.

    2016-02-01

    Optical coherence tomography (OCT) and blue light cystoscopy (BLC) have shown significant potential as complementary technologies to traditional white light cystoscopy (WLC) for early bladder cancer detection. Three-dimensional (3D) organ-mimicking phantoms provide realistic imaging environments for testing new technology designs, the diagnostic potential of systems, and novel image processing algorithms prior to validation in real tissue. Importantly, the phantom should mimic features of healthy and diseased tissue as they appear under WLC, BLC, and OCT, which are sensitive to tissue color and structure, fluorescent contrast, and optical scattering of subsurface layers, respectively. We present a phantom posing the hollow shape of the bladder and fabricated using a combination of 3D-printing and spray-coating with Dragon Skin (DS) (Smooth-On Inc.), a highly elastic polymer to mimic the layered structure of the bladder. Optical scattering of DS was tuned by addition of titanium dioxide, resulting in scattering coefficients sufficient to cover the human bladder range (0.49 to 2.0 mm^-1). Mucosal vasculature and tissue coloration were mimicked with elastic cord and red dye, respectively. Urethral access was provided through a small hole excised from the base of the phantom. Inserted features of bladder pathology included altered tissue color (WLC), fluorescence emission (BLC), and variations in layered structure (OCT). The phantom surface and underlying material were assessed on the basis of elasticity, optical scattering, layer thicknesses, and qualitative image appearance. WLC, BLC, and OCT images of normal and cancerous features in the phantom qualitatively matched corresponding images from human bladders.

  20. Thermal structures and materials for high-speed flight; Collection of Papers of the 1st Thermal Structures Conference, University of Virginia, Charlottesville, Nov. 13-15, 1990

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Thornton, E.A.

    1992-01-01

    The present conference discusses aerobrake-maneuver vehicle aerothermodynamics, aerothermal issues in the structural design of high speed vehicles, laser surface-alloying of superlight metals with ceramic surfaces, high-temperature Al alloys for supersonic and hypersonic vehicles, advanced metallics for high temperature airframes, novel materials for engine applications, and the development status of computational methods for high temperature structural design. Also discussed are a transient thermal-structural analysis using adaptive unstructured remeshing and mesh movement, the FEM thermoviscoplastic analysis of aerospace structures, hot-structures testing techniques, a thermal-structural analysis of a carbon-carbon/refractory metal heat pipe-cooled leading edge, dynamic effects in thermoviscoplastic structures, microlevel thermal effects inmore » metal-matrix composites (MMCs), thermomechanical effects in the plasma spray manufacture of MMC monotapes, and intelligent HIP processing. Most of the presentations at this conference were abstracted previously (see A91-16027 to A91-16047).« less

  1. Fibre Concrete 2017

    NASA Astrophysics Data System (ADS)

    2017-09-01

    9th international conference on fibre reinforced concretes (FRC), textile reinforced concretes (TRC) and ultra-high performance concretes (UHPC) Preface The Fibre Concrete Conference series is held biennially to provide a platform to share knowledge on fibre reinforced concretes, textile concretes and ultra-high performance concretes regarding material properties and behaviour, technology procedures, topics of long-term behaviour, creep, durability; sustainable aspects of concrete including utilisation of waste materials in concrete production and recycling of concrete. The tradition of Fibre Concrete Conferences started in eighties of the last century. Nowadays the conference is organized by the Department of Concrete and Masonry Structures of the Czech Technical University in Prague, Faculty of Civil Engineering. The 9th International Conference Fibre Concrete 2017 had 109 participants from 27 countries all over the world. 55 papers were presented including keynote lectures of Professor Bažant, Professor Bartoš and Dr. Broukalová. The conference program covered wide range of topics from scientific research to practical applications. The presented contributions related to performance and behaviour of cement based composites, their long-term behaviour and durability, sustainable aspects, advanced analyses of structures from these composites and successful applications. This conference was organized also to honour Professor Zděnek P. Bažant on the occasion of his jubilee and to appreciate his merits and discoveries in the field of fibre reinforced composites, structural mechanics and engineering.

  2. The 16th International Conference on X-ray Absorption Fine Structure (XAFS16)

    NASA Astrophysics Data System (ADS)

    Grunwaldt, J.-D.; Hagelstein, M.; Rothe, J.

    2016-05-01

    This preface of the proceedings volume of the 16th International Conference on X- ray Absorption Fine Structure (XAFS16) gives a glance on the five days of cutting-edge X-ray science which were held in Karlsruhe, Germany, August 23 - 28, 2015. In addition, several satellite meetings took place in Hamburg, Berlin and Stuttgart, a Sino-German workshop, three data analysis tutorials as well as special symposia on industrial catalysis and XFELs were held at the conference venue.

  3. ALT-C 95: Changing Education, Changing Technology. Conference Abstracts of the Association for Learning Technology Conference (2nd, Milton Keynes, England, United Kingdom, September 11-13, 1995).

    ERIC Educational Resources Information Center

    Hawkridge, David, Ed.

    This program for the 1995 Association for Learning Technology Conference summarizes the presentations of the discussions, demonstrations, workshops, and poster sessions. Abstracts of the following papers presented at the conference are included: "New Structures for Learning" (Patrick Allen & Kate Sankey); "Multiple System…

  4. The Development of FE IV (Further Education). Coombe Lodge Report, Study Conference 75/20 and Study Conference 75/24.

    ERIC Educational Resources Information Center

    Further Education Staff Coll., Blagdon (England).

    The conferences were part of a series on the development of the field of postsecondary education in Britain. Proceedings of the first conference, on the development of new college organizational structures, include: the concept of organizational development (A.B. Cherns); organization and education (G.M.A. Harrison); introduction to a project to…

  5. Guidance and control, 1993; Annual Rocky Mountain Guidance and Control Conference, 16th, Keystone, CO, Feb. 6-10, 1993

    NASA Technical Reports Server (NTRS)

    Culp, Robert D. (Editor); Bickley, George (Editor)

    1993-01-01

    Papers from the sixteenth annual American Astronautical Society Rocky Mountain Guidance and Control Conference are presented. The topics covered include the following: advances in guidance, navigation, and control; control system videos; guidance, navigation and control embedded flight control systems; recent experiences; guidance and control storyboard displays; and applications of modern control, featuring the Hubble Space Telescope (HST) performance enhancement study.

  6. Proceedings of the Annual Meeting of the International Group for the Psychology of Mathematics Education (PME) (28th, Bergen, Norway, July 14-18, 2004). Volume 4

    ERIC Educational Resources Information Center

    Hoines, Marit Johnsen, Ed.; ; Fuglestad, Anne Berit, Ed.

    2004-01-01

    This document contains the fourth volume of the proceedings of the 28th annual conference of the International Group for the Psychology of Mathematics Education. Conference presentations are centered around the theme "Inclusion and Diversity". This volume features 64 research report papers: (1) Situated or Abstract: The Effect of Combining Context…

  7. Proceedings of the Conference on Graduate Student Research in Engineering and Technology Education (Minneapolis, Minnesota, May 22, 2008)

    ERIC Educational Resources Information Center

    National Center for Engineering and Technology Education, 2008

    2008-01-01

    As part of the usual end of year meeting that has been a feature of the National Center for Engineering and Technology Education (NCETE) project, a conference intending to provide a forum for young voices in an outside of the Center was organized. The basic model for the gathering was borrowed from track and field. This was to be an intellectual…

  8. Proceedings of the Annual Meeting of the International Group for the Psychology of Mathematics Education (PME) (28th, Bergen, Norway, July 14-18, 2004). Volume 1

    ERIC Educational Resources Information Center

    Hoines, Marit Johnsen, Ed.; ; Fuglestad, Anne Berit, Ed.

    2004-01-01

    This document contains the first volume of the proceedings of the 28th Annual Conference of the International Group for the Psychology of Mathematics Education. Conference presentations are centered around the theme "Inclusion and Diversity". In total, 147 presentations centered around the vision of mathematics for all. This volume features eight…

  9. [Summary of the World Conference on Education for All.] The Major Project in the Field of Education in the Latin American and Caribbean Region. Bulletin 21.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Santiago (Chile). Regional Office for Education in Latin America and Caribbean.

    This bulletin features four papers, a summary of the World Conference on Education for All held in Jomtien, Thailand in March of 1990, the World Declaration on Education for All, and a framework for action to meet basic learning needs. The four presentations include: "Educational Planning in the Future" (Jesus M. Gurriaran); "An…

  10. Proceedings of the Conference of the International Group for the Psychology of Mathematics Education (25th, Utrecht, The Netherlands, July 12-17, 2001). Volumes 1-4.

    ERIC Educational Resources Information Center

    van den Heuvel-Panhuizen, Marja, Ed.

    This document contains the proceedings of the 25th annual Conference of the International Group for the Psychology of Mathematics Education (PME). It features plenary lectures, research forums, discussion groups, working sessions, short oral communications, and poster presentations. Papers in Volume 1 include: (1) "The P in PME: Progress and…

  11. Motor cortex embeds muscle-like commands in an untangled population response

    PubMed Central

    Russo, Abigail A.; Bittner, Sean R.; Perkins, Sean M.; Seely, Jeffrey S.; London, Brian M.; Lara, Antonio H.; Miri, Andrew; Marshall, Najja J.; Kohn, Adam; Jessell, Thomas M.; Abbott, Laurence F.; Cunningham, John P.; Churchland, Mark M.

    2018-01-01

    Summary Primate motor cortex projects to spinal interneurons and motor neurons, suggesting that motor cortex activity may be dominated by muscle-like commands. Extensive observations during reaching lend support to this view, but evidence remains ambiguous and much-debated. To provide a different perspective, we employed a novel behavioral paradigm that affords extensive comparison between time-evolving neural and muscle activity. We found that single motor cortex neurons displayed many muscle-like properties, but the structure of population activity was not muscle-like. Unlike muscle activity, neural activity was structured to avoid ‘tangling’: moments where similar activity patterns led to dissimilar future patterns. Avoidance of tangling was present across tasks and species. Network models revealed a potential reason for this consistent feature: low tangling confers noise robustness. Finally, we were able to predict motor cortex activity from muscle activity alone, by leveraging the hypothesis that muscle-like commands are embedded in additional structure that yields low tangling. PMID:29398358

  12. Conference report: reviving pharmaceutical R&D with translational science, regulatory efficiency and innovative models.

    PubMed

    Zhang, Tianyi Tee; Weng, Naidong; Lee, Mike

    2013-10-01

    The 4th Annual Shanghai Symposium on Clinical & Pharmaceutical Solutions through Analysis (CPSA Shanghai 2013) was held on 24-27 April 2013 in Shanghai, China. The meeting provided an educational forum for scientists from pharmaceutical industry, academia, CROs and instrument vendors to share experience and ideas, and discuss current challenges, issues and innovative solutions associated with pharmaceutical R&D. The meeting featured highly interactive events, including diversified symposia, roundtable discussions, workshops, poster sessions and conference awards. Education and specialized training are the foundation of CPSA events. The CPSA Shanghai 2013 meeting also featured an inaugural satellite workshop event in Beijing, as well as joint sessions traditionally held with local bioanalytical and drug metabolism discussion groups.

  13. The 1991 International Conference on Aging Aircraft and Structural Airworthiness

    NASA Technical Reports Server (NTRS)

    Harris, Charles E. (Editor)

    1992-01-01

    Technical sessions of the conference included structural performance, nondestructive evaluation, maintenance and repair, international activities, and commuter airlines. Each session was organized to provide a well-rounded view of the subject from the industry, regulatory, and research perspective. Thirty-four presentations were given by the international technical community.

  14. Multi-scale Imaging of Cellular and Sub-cellular Structures using Scanning Probe Recognition Microscopy.

    NASA Astrophysics Data System (ADS)

    Chen, Q.; Rice, A. F.

    2005-03-01

    Scanning Probe Recognition Microscopy is a new scanning probe capability under development within our group to reliably return to and directly interact with a specific nanobiological feature of interest. In previous work, we have successfully recognized and classified tubular versus globular biological objects from experimental atomic force microscope images using a method based on normalized central moments [ref. 1]. In this paper we extend this work to include recognition schemes appropriate for cellular and sub-cellular structures. Globular cells containing tubular actin filaments are under investigation. Thus there are differences in external/internal shapes and scales. Continuous Wavelet Transform with a differential Gaussian mother wavelet is employed for multi- scale analysis. [ref. 1] Q. Chen, V. Ayres and L. Udpa, ``Biological Investigation Using Scanning Probe Recognition Microscopy,'' Proceedings 3rd IEEE Conference on Nanotechnology, vol. 2, p 863-865 (2003).

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Strickland, Madeleine; Stanley, Ann Marie; Wang, Guangshun

    Paralogous enzymes arise from gene duplication events that confer a novel function, although it is unclear how cross-reaction between the original and duplicate protein interaction network is minimized. We investigated HPr:EIsugar and NPr:EINtr, the initial complexes of paralogous phosphorylation cascades involved in sugar import and nitrogen regulation in bacteria, respectively. Although the HPr:EIsugar interaction has been well characterized, involving multiple complexes and transient interactions, the exact nature of the NPr:EINtr complex was unknown. We set out to identify the key features of the interaction by performing binding assays and elucidating the structure of NPr in complex with the phosphorylation domainmore » of EINtr (EINNtr), using a hybrid approach involving X-ray, homology, and sparse nuclear magnetic resonance. We found that the overall fold and active-site structure of the two complexes are conserved in order to maintain productive phosphorylation, however, the interface surface potential differs between the two complexes, which prevents cross-reaction.« less

  16. Internet conferences in glycobiology.

    PubMed

    Hardy, B J; Doughty, S W; Parretti, M F; Tennison, J; Wilson, I

    1997-09-01

    In this article we describe recent activities in the use of electronic conferencing in glycobiology focusing on our experiences with the organization and development of the Second Electronic Glycoscience Conference (EGC-2), which was held on the Internet and World Wide Web in September 1996. EGC-2 involved the presentation and discussion of scientific research results in a virtual conferencing environment which incorporated virtual replicas of many activities usually observed at a physical conference in addition to features unique to the electronic medium. Highlights of the scientific program and technical developments in the design and use of these facilities are briefly described. EGC-3 will be held in October 1997.

  17. FOREWORD: Foreword

    NASA Astrophysics Data System (ADS)

    MacLaren, Ian

    2014-06-01

    EMAG2013 was certainly the biggest EMAG conference I can remember in my twenty years of going to EMAG conferences. We had a total of about 180 scientific delegates, not including exhibitors. The conference also benefited from the York conference centre allowing us to integrate the scientific sessions, refreshments and exhibition in one building. This all made for a very vibrant and focused conference. The quality of the presentations was again very high and judging by many of the student talks given, there is plenty of hope for an excellent future for electron microscopy in the UK. A unique feature of this conference was a chance to organise a session to commemorate the 80th year of one of the pioneers of electron microscopy in the UK, Professor Archie Howie. An excellent symposium was organised in his honour by one of his former students, Professor Pratibha Gai of the University of York. This was dedicated to one field that he made some important initial contributions to: in-situ microscopy. The symposium gave a depth and breadth of overview to this field unusual at an EMAG conference, with speakers from the UK, Europe, Japan and the USA and gave a real taste of some of the possibilities in the latest instruments to observe real materials at work at nanometre or even atomic resolution. Professor Howie himself gave a highly entertaining retrospective of his time working in microscopy from the 1950s until the present in his talk after the conference dinner on the Thursday evening at the excellent York National Railway Museum. We also had excellent plenary lectures from Professor Wolfgang Baumeister on a topic perhaps novel to many at EMAG, TEM in Structural Biology; from Professor Prathibha Gai on atomic resolution in-situ studies of chemical reactions in the TEM; and Professor Archie Howie discussing some of the important current open questions in TEM and STEM. This proceedings therefore presents a snapshot of a broad cross-section of the exciting work going on in electron microscopy in 2013. As always, the papers are ordered thematically according to the sessions organised at the conference. As ever, I have a great debt of gratitude to my fellow EMAG committee members who chaired the various sessions and who, together with the programme chair, Dr Cate Ducati of the University of Cambridge helped to put together such an excellent programme. I also gratefully acknowledge the many hours invested by Professor Pete Nellist of the University of Oxford who then edited this proceedings and ensured that the peer review and revision process ran as smoothly as possible. Finally, I hope that you enjoy reading the contributions made by many to this excellent conference. Dr Ian MacLaren, Chair of the Electron Microscopy and Analysis Group

  18. Preface: Special issue featuring papers from the International Conference on Nonequilibrium Carrier Dynamics in Semiconductors

    NASA Astrophysics Data System (ADS)

    Reggiani, L.; Bordone, P.; Brunetti, R.

    2004-02-01

    The International Conference on Nonequilibrium Carrier Dynamics in Semiconductors (HCIS-13) celebrates 30 years since it first took place in Modena. Nonequilibrium dynamics of charge carriers, pioneered by the hot-electron concept, is an important issue for understanding electro-optic transport properties in semiconductor materials and structures. In these 30 years several topics have matured, and new ones have emerged thus fertilizing the field with a variety of physical problems and new ideas. The history of the conference is summarized in the opening paper `30 years of HCIS'. The future of the conference seems secure considering the continued lively interest of the participants. The conference addressed eleven major topics which constitute the backbone of the proceedings and are summarized as follows: carrier transport in low dimensional and nanostructure systems, nonequilibrium carriers in superlattices and devices, small devices and related phenomena, carrier dynamics and fluctuations, carrier quantum dynamics, coherent/incoherent carrier dynamics of optical excitations and ultra-fast optical phenomena, nonlinear optical effects, transport in organic matter, semiconductor-based spintronics, coherent dynamics in solid state systems for quantum processing and communication, novel materials and devices. Nanometric space scale and femtosecond time scale represent the ultimate domains of theoretical, experimental and practical interest. Traditional fields such as bulk properties, quantum transport, fluctuations and chaotic phenomena, etc, have received thorough and continuous attention. Emerging fields from previous conferences, such as quantum processing and communication, have been better assessed. New fields, such as spintronics and electron transport in organic matter, have appeared for the first time. One plenary talk, 11 invited talks, 230 submitted abstracts covering all these topics constituted a single-session conference. Following scientific selection through the Advisory and Program Committees and peer review, 162 papers were selected for publication by the Institute of Physics Publishing in this special issue of Semiconductor Science and Technology. The financial support that allowed conference organization and helped researchers with budget difficulties to attend came from the following institutions which are gratefully acknowledged: Office of Naval Research (ONR), Defense Advanced Research Project Agency (DARPA), Office of Naval Research International Field Office (ONRIFO), International Union of Pure and Applied Physics (IUPAP), Italian Ministry of Education University and Research (MIUR), National Institute for the Physics of Matter (INFM), University of Modena and Reggio Emilia, Dipartimento di Ingegneria dell’ Innovazione of the Lecce University. Finally, sincere thanks are addressed to the technical staff who provided assistance during the conference: G Angelone, M Benassi, F Grossi, M Leuzzi, A Magnani, S Montanto, L Zagni and D Zanfi. The staff of the University Press Office together with F Goggi and N Minto are acknowledged for their excellent job in printing the conference documents.

  19. New Minority Groups in the Citadel of Europe. General Report of a Multidisciplinary Conference on the Educational and Cultural Aspects of Community Relations (Strasbourg, France, December 5-7, 1989).

    ERIC Educational Resources Information Center

    Berque, Jacques

    Large numbers of persons of African and Asiatic descent have immigrated to the countries of Western Europe in recent decades, and their presence has raised significant problems in terms of racial and cultural relations for European leaders. This document features the general report from a conference sponsored by the Council of Europe's Council for…

  20. Collections: Their Development, Management, Preservation, and Sharing. Papers from the Joint Meeting of the Association of Research Libraries and the Standing Conference of National and University Libraries (York, England, September 19-22, 1988).

    ERIC Educational Resources Information Center

    Daval, Nicola, Ed.

    Papers from the joint meeting are assembled in this document. Each of the meeting's five program sessions featured presentations by a Standing Conference of National and Universal Libraries (SCONUL) director and an Association of Research Libraries (ARL) director. The presentations highlight perspectives from both sides of the Atlantic and are…

  1. "Team Leadership Training in Vocational Special Needs." Proceedings: Annual Statewide Conference on Vocational Special Needs (3rd, College Station, Texas, April 16,17, and 18, 1979).

    ERIC Educational Resources Information Center

    Kok, Marilyn, Ed.; And Others

    These proceedings of a statewide Texas conference focus on the need for cooperation between the leadership in the fields of special and vocational education in order to meet the needs of handicapped students. Featured presentations (1) stress the necessity for this team approach at the top levels of the education-state agency bureaucracy as well…

  2. Sea monsters & whirlpools: Navigating between examination and reflection in medical education.

    PubMed

    Hodges, Brian David

    2015-03-01

    The 16th International Ottawa Conference/Canadian Conference on Medical Education (2014) featured a keynote deconstructing the rising discourse of competence-as-reflection in medical education. This paper, an elaborated version of the presentation, is an investigation into the theoretical roots of the diverse forms of reflective practice that are being employed by medical educators. It also raises questions about the degree to which any of these practices is compatible with assessment.

  3. One-Dimensional Modeling Studies of the Gaseous Electronics Conference RF Reference Cell

    PubMed Central

    Govindan, T. R.; Meyyappan, M.

    1995-01-01

    A review of the one-dimensional modeling studies in the literature of the Gaseous Electronics Conference (GEC) reference plasma reactor is presented. Most of the studies are based on the fluid model description of the discharge and some utilize hybrid fluid-kinetic schemes. Both models are discussed here briefly. The models provide a basic understanding of the discharge mechanisms and reproduce several critical discharge features observed experimentally. PMID:29151755

  4. Significant Wilderness Qualities: Can They Be Identified and Monitored? Proceedings of the Annual NOLS [National Outdoor Leadership School] Wilderness Research Colloquium (3rd, Shoshone National Forest, Wyoming, August 10-15, 1987).

    ERIC Educational Resources Information Center

    Cole, David N., Comp.; Lucas, Robert C., Comp.

    This report is a compilation of the papers presented at a colloquium on wilderness management and a synopsis of discussions held during the conference. The conference theme was how to determine and monitor the most significant features and qualities of the wilderness resource. Generally, participants identify solitude; pollution-free air and…

  5. Preface - 'NANOSMAT-Paris 2017'

    NASA Astrophysics Data System (ADS)

    De Hosson, Jeff Th. M.; Ali, Nasar; Fierro, Giuseppe; Aliofkhazraei, Mahmood; Chipara, Mircea

    2018-07-01

    The "International Conference on Surfaces, Coatings and Nano-Structured Materials" (NANOSMAT) has rapidly emerged as the premier conference in the field of materials science, engineering, technology and all aspects of "nano". The 12th International Conference on Surfaces, Coatings and Nanostructured Materials (NANOSMAT) was held at the Pierre & Marie Curie University in Paris, France. This conference is in the NANOSMAT conference series. The first two NANOSMAT conferences were held in Portugal (2005, 2007), whereas, the subsequent NANOSMAT meetings were held in Barcelona (Spain), Rome (Italy), Reims (France), Krakow (Poland), Prague (Czech Republic), Granada (Spain), Dublin (Ireland), Manchester (UK) and Aveiro (Portugal).

  6. Resource-Bounded Information Acquisition and Learning

    DTIC Science & Technology

    2012-05-01

    candidate features arrive one at a time, and the learner’s task is to select a ‘best so far’ set of features from streaming features. Krause et al...on Artificial Intelligence. [31] Gatterbauer, Wolfgang . Estimating required recall for successful knowledge acquisition from the web. In Proceedings of...the 15th international conference on World Wide Web (New York, NY, USA, 2006), WWW ’06, ACM, pp. 969– 970. [32] Gatterbauer, Wolfgang . Rules of thumb

  7. Structure of Radical-Induced Cell Death1 Hub Domain Reveals a Common αα-Scaffold for Disorder in Transcriptional Networks.

    PubMed

    Bugge, Katrine; Staby, Lasse; Kemplen, Katherine R; O'Shea, Charlotte; Bendsen, Sidsel K; Jensen, Mikael K; Olsen, Johan G; Skriver, Karen; Kragelund, Birthe B

    2018-05-01

    Communication within cells relies on a few protein nodes called hubs, which organize vast interactomes with many partners. Frequently, hub proteins are intrinsically disordered conferring multi-specificity and dynamic communication. Conversely, folded hub proteins may organize networks using disordered partners. In this work, the structure of the RST domain, a unique folded hub, is solved by nuclear magnetic resonance spectroscopy and small-angle X-ray scattering, and its complex with a region of the transcription factor DREB2A is provided through data-driven HADDOCK modeling and mutagenesis analysis. The RST fold is unique, but similar structures are identified in the PAH (paired amphipathic helix), TAFH (TATA-box-associated factor homology), and NCBD (nuclear coactivator binding domain) domains. We designate them as a group the αα hubs, as they share an αα-hairpin super-secondary motif, which serves as an organizing platform for malleable helices of varying topology. This allows for partner adaptation, exclusion, and selection. Our findings provide valuable insights into structural features enabling signaling fidelity. Copyright © 2018 Elsevier Ltd. All rights reserved.

  8. Structural Analysis of the Synaptic Protein Neuroligin and Its β-Neurexin Complex: Determinants for Folding and Cell Adhesion

    PubMed Central

    Fabrichny, Igor P.; Leone, Philippe; Sulzenbacher, Gerlind; Comoletti, Davide; Miller, Meghan T.; Taylor, Palmer; Bourne, Yves; Marchot, Pascale

    2009-01-01

    SUMMARY The neuroligins are postsynaptic cell adhesion proteins whose associations with presynaptic neurexins participate in synaptogenesis. Mutations in the neuroligin and neurexin genes appear to be associated with autism and mental retardation. The crystal structure of a neuroligin reveals features not found in its catalytically active relatives, such as the fully hydrophobic interface forming the functional neuroligin dimer; the conformations of surface loops surrounding the vestigial active center; the location of determinants that are critical for folding and processing; and the absence of a macromolecular dipole and presence of an electronegative, hydrophilic surface for neurexin binding. The structure of a β-neurexin-neuroligin complex reveals the precise orientation of the bound neurexin and, despite a limited resolution, provides substantial information on the Ca2+-dependent interactions network involved in trans-synaptic neurexin-neuroligin association. These structures exemplify how an α/β-hydrolase fold varies in surface topography to confer adhesion properties and provide templates for analyzing abnormal processing or recognition events associated with autism. PMID:18093521

  9. International conference on "Photosynthesis Research for Sustainability-2016" : In honor of Nathan Nelson and Turhan Nejat Veziroğlu.

    PubMed

    Tsygankov, Anatoly A; Allakhverdiev, Suleyman I; Tomo, Tatsuya; Govindjee

    2017-02-01

    During June 19-26, 2016, an international conference ( http://photosynthesis2016.cellreg.org/ ) on "Photosynthesis Research for Sustainability-2016" was held in honor of Nathan Nelson and Turhan Nejat Veziroğlu at the Institute of Basic Biological Problems, Russian Academy of Sciences, formerly Institute of Photosynthesis, Academy of Sciences of the USSR, Pushchino, Russia. Further, this conference celebrated the 50th anniversary of the Institute. We provide here a brief introduction and key contributions of the two honored scientists, and then information on the conference, on the speakers, and the program. A special feature of this conference was the awards given to several young investigators, who are recognized in this Report. Several photographs are included to show the excellent ambience at this conference. We invite the readers to the next conference on "Photosynthesis and Hydrogen Energy Research for Sustainability-2017", which will honor A.S. Raghavendra (of University of Hyderabad), William Cramer (of Purdue University) and Govindjee (of University of Illinois at Urbana-Champaign); it will be held during the Fall of 2017 (from October 30 to November 4), at the University of Hyderabad, Hyderabad, India. See < https://prs.science >.

  10. Molecular Signatures of Tissue-Specific Microvascular Endothelial Cell Heterogeneity in Organ Maintenance and Regeneration

    PubMed Central

    Nolan, Daniel J.; Ginsberg, Michael; Israely, Edo; Palikuqi, Brisa; Poulos, Michael G.; James, Daylon; Ding, Bi-Sen; Schachterle, William; Liu, Ying; Rosenwaks, Zev; Butler, Jason M.; Xiang, Jenny; Rafii, Arash; Shido, Koji; Rabbany, Sina Y.; Elemento, Olivier; Rafii, Shahin

    2013-01-01

    SUMMARY Microvascular endothelial cells (ECs) within different tissues are endowed with distinct but as yet unrecognized structural, phenotypic, and functional attributes. We devised EC purification, cultivation, profiling, and transplantation models that establish tissue-specific molecular libraries of ECs devoid of lymphatic ECs or parenchymal cells. These libraries identify attributes that confer ECs with their organotypic features. We show that clusters of transcription factors, angiocrine growth factors, adhesion molecules, and chemokines are expressed in unique combinations by ECs of each organ. Furthermore, ECs respond distinctly in tissue regeneration models, hepatectomy, and myeloablation. To test the data set, we developed a transplantation model that employs generic ECs differentiated from embryonic stem cells. Transplanted generic ECs engraft into regenerating tissues and acquire features of organotypic ECs. Collectively, we demonstrate the utility of informational databases of ECs toward uncovering the extravascular and intrinsic signals that define EC heterogeneity. These factors could be exploited therapeutically to engineer tissue-specific ECs for regeneration. PMID:23871589

  11. Oncogene-like induction of cellular invasion from centrosome amplification

    PubMed Central

    Godinho, Susana A.; Picone, Remigio; Burute, Mithila; Dagher, Regina; Su, Ying; Leung, Cheuk T.; Polyak, Kornelia; Brugge, Joan S.; Thery, Manuel; Pellman, David

    2014-01-01

    Centrosome amplification has long been recognized as a feature of human tumors, however its role in tumorigenesis remains unclear1. Centrosome amplification is poorly tolerated by non-transformed cells, and, in the absence of selection, extra centrosomes are spontaneously lost2. Thus, the high frequency of centrosome amplification, particularly in more aggressive tumors3, raises the possibility that extra centrosomes could, in some contexts, confer advantageous characteristics that promote tumor progression. Using a three-dimensional model system and other approaches to culture human mammary epithelial cells, we find that centrosome amplification triggers cell invasion. This invasive behavior is similar to that induced by overexpression of the breast cancer oncogene ErbB24 and indeed enhances invasiveness triggered by ErbB2. We show that, through increased centrosomal microtubule nucleation, centrosome amplification increases Rac1 activity, which disrupts normal cell-cell adhesion and promotes invasion. These findings demonstrate that centrosome amplification, a structural alteration of the cytoskeleton, can promote features of malignant transformation. PMID:24739973

  12. Parity Now!

    ERIC Educational Resources Information Center

    Library Journal, 1971

    1971-01-01

    The preconference on Recruitment of Minorities featured a diversified program with an array of speakers, a panel discussion, concurrent sessions on problem solving, and summaries and critiques from two conference "floaters." (Author)

  13. 2009 Gordon Research Conference, Applied and Environmental Microbiology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dubilier, Nicole

    The topic of the 2009 Gordon Conference on Applied and Environmental Microbiology is: From Single Cells to the Environment. The Conference will present and discuss cutting-edge research on applied and environmental microbiology with a focus on understanding interactions between microorganisms and the environment at levels ranging from single cells to complex communities. The Conference will feature a wide range of topics such as single cell techniques (including genomics, imaging, and NanoSIMS), microbial diversity at scales ranging from clonal to global, environmental 'meta-omics', biodegradation and bioremediation, metal - microbe interactions, animal microbiomes and symbioses. The Conference will bring together investigators whomore » are at the forefront of their field, and will provide opportunities for junior scientists and graduate students to present their work in poster format and exchange ideas with leaders in the field. Some poster presenters will be selected for short talks. The collegial atmosphere of this Conference, with extensive discussion sessions as well as opportunities for informal gatherings in the afternoons and evenings, provides an ideal setting for scientists from different disciplines to exchange ideas, brainstorm and discuss cross-disciplinary collaborations.« less

  14. International conference on "Photosynthesis Research for Sustainability-2014: in honor of Vladimir A. Shuvalov", held on June 2-7, 2014, in Pushchino, Russia.

    PubMed

    Allakhverdiev, Suleyman I; Tomo, Tatsuya; Govindjee

    2014-12-01

    In this article, we provide a News Report on an international conference "Photosynthesis Research for Sustainability-2014" that was held in honor of Vladimir A. Shuvalov at the Biological Research Center of the Russian Academy of Sciences, in Pushchino, Russia, during June 2-7, 2014 (http://photosynthesis2014.cellreg.org/). We begin this report with a short description of Vladimir A. Shuvalov, the honored scientist. We then provide some information on the conference, and the program. A special feature of this conference was awards given to nine young investigators; they are recognized in this Report. We have also included several photographs to show the pleasant ambiance at this conference. We invite the readers to the next two conferences on ''Photosynthesis Research for Sustainability-2015: the first one to be held in Baku in May or June, 2015, and the second one, which will honor George C. Papageorgiou, will be held in Greece (in Colymbari, near Chania in Crete) during September 21-26, 2015. Information will be posted at: http://photosynthesis2015.cellreg.org/.

  15. Electromagnetic and light scattering by nonspherical particles XVI

    NASA Astrophysics Data System (ADS)

    Berg, Matthew J.; Eversole, Jay D.; Kolokolova, Ludmilla; Mishchenko, Michael I.; Videen, Gorden

    2017-11-01

    The 16th Electromagnetic and Light Scattering Conference (ELS-XVI) was held in College Park, MD from 19-25 March 2017 (Fig. 1). This conference built on the success of the previous meetings held in Amsterdam (1995) [1], Helsinki (1997) [2], New York (1998) [3], Vigo (1999), Halifax (2000) [4], Gainesville (2002) [5], Bremen (2003) [6], Salobreña (2005) [7], St. Petersburg (2006) [8], Bodrum (2007) [9], Hatfield (2008) [10], Helsinki (2010) [11], Taormina (2011) [12], Lille (2013) [13], and Leipzig (2015) [14], as well as of three related workshops held in Bremen (1996, 1998) and Moscow (1997). As before, the main objective of this conference was to assemble scientists, engineers, and PhD students researching various aspects of electromagnetic scattering by particles and particle groups and to provide a stimulating atmosphere for in-depth discussions of theory, measurements, and applications. The conference featured 143 presentations by 132 registered participants from 18 countries. The program and the abstracts of conference presentations are available at the official conference web site https://www.giss.nasa.gov/staff/mmishchenko/ELS-XVI.

  16. Real-Time Peer Review: An Innovative Feature to an Evidence-Based Practice Conference

    PubMed Central

    Eldredge, Jonathan D.; Phillips, Holly E.; Kroth, Philip J.

    2013-01-01

    Many health sciences librarians as well as other professionals attend conferences on a regular basis. This study sought to link an innovative peer review process of presented research papers to long-term conference outcomes in the peer-reviewed professional journal literature. An evidence-based conference included a proof-of-concept study to gauge the long-term outcomes from research papers presented during the program. Real-time peer review recommendations from the conference were linked to final versions of articles published in the peer-reviewed literature. The real-time peer review feedback served as the basis for further mentoring to guide prospective authors toward publishing their research results. These efforts resulted in the publication of two of the four research papers in the peer-viewed literature. A third presented paper appeared in a blog because the authors wanted to disseminate their findings more quickly than through the journal literature. The presenters of the fourth paper never published their study. Real-time peer review from this study can be adapted to other professional conferences that include presented research papers. PMID:24180649

  17. The Third Solar Wind Conference: A summary

    NASA Technical Reports Server (NTRS)

    Russell, C. T.

    1974-01-01

    The Third Solar Wind Conference consisted of nine sessions. The following subjects were discussed: (1) solar abundances; (2) the history and evolution of the solar wind; (3) the structure and dynamics of the solar corona; (4) macroscopic and microscopic properties of the solar wind; (5) cosmic rays as a probe of the solar wind; (6) the structure and dynamics of the solar wind; (7) spatial gradients; (8) stellar winds; and (9) interactions with objects in the solar wind. The invited and contributed talks presented at the conference are summarized.

  18. Identification of Site-Specific Adaptations Conferring Increased Neural Cell Tropism during Human Enterovirus 71 Infection

    PubMed Central

    Schibler, Manuel; Martinez, Yannick; Gerlach, Daniel; van Belle, Sandra; Turin, Lara; Zdobnov, Evgeny; Kaiser, Laurent; Tapparel, Caroline

    2012-01-01

    Enterovirus 71 (EV71) is one of the most virulent enteroviruses, but the specific molecular features that enhance its ability to disseminate in humans remain unknown. We analyzed the genomic features of EV71 in an immunocompromised host with disseminated disease according to the different sites of infection. Comparison of five full-length genomes sequenced directly from respiratory, gastrointestinal, nervous system, and blood specimens revealed three nucleotide changes that occurred within a five-day period: a non-conservative amino acid change in VP1 located within the BC loop (L97R), a region considered as an immunogenic site and possibly important in poliovirus host adaptation; a conservative amino acid substitution in protein 2B (A38V); and a silent mutation in protein 3D (L175). Infectious clones were constructed using both BrCr (lineage A) and the clinical strain (lineage C) backgrounds containing either one or both non-synonymous mutations. In vitro cell tropism and competition assays revealed that the VP197 Leu to Arg substitution within the BC loop conferred a replicative advantage in SH-SY5Y cells of neuroblastoma origin. Interestingly, this mutation was frequently associated in vitro with a second non-conservative mutation (E167G or E167A) in the VP1 EF loop in neuroblastoma cells. Comparative models of these EV71 VP1 variants were built to determine how the substitutions might affect VP1 structure and/or interactions with host cells and suggest that, while no significant structural changes were observed, the substitutions may alter interactions with host cell receptors. Taken together, our results show that the VP1 BC loop region of EV71 plays a critical role in cell tropism independent of EV71 lineage and, thus, may have contributed to dissemination and neurotropism in the immunocompromised patient. PMID:22910880

  19. HIV Conference to Be Held on October 21 at NCI at Frederick | Poster

    Cancer.gov

    By Anne Arthur, Guest Writer The HIV Drug Resistance Program Conference on “Virus Structure: Putting the Pieces Together” will be held at NCI at Frederick on October 21, 2014, from 1:00 to 5:45 p.m. in the Conference Center auditorium, Building 549.

  20. Bioinformatics analyses of Shigella CRISPR structure and spacer classification.

    PubMed

    Wang, Pengfei; Zhang, Bing; Duan, Guangcai; Wang, Yingfang; Hong, Lijuan; Wang, Linlin; Guo, Xiangjiao; Xi, Yuanlin; Yang, Haiyan

    2016-03-01

    Clustered regularly interspaced short palindromic repeats (CRISPR) are inheritable genetic elements of a variety of archaea and bacteria and indicative of the bacterial ecological adaptation, conferring acquired immunity against invading foreign nucleic acids. Shigella is an important pathogen for anthroponosis. This study aimed to analyze the features of Shigella CRISPR structure and classify the spacers through bioinformatics approach. Among 107 Shigella, 434 CRISPR structure loci were identified with two to seven loci in different strains. CRISPR-Q1, CRISPR-Q4 and CRISPR-Q5 were widely distributed in Shigella strains. Comparison of the first and last repeats of CRISPR1, CRISPR2 and CRISPR3 revealed several base variants and different stem-loop structures. A total of 259 cas genes were found among these 107 Shigella strains. The cas gene deletions were discovered in 88 strains. However, there is one strain that does not contain cas gene. Intact clusters of cas genes were found in 19 strains. From comprehensive analysis of sequence signature and BLAST and CRISPRTarget score, the 708 spacers were classified into three subtypes: Type I, Type II and Type III. Of them, Type I spacer referred to those linked with one gene segment, Type II spacer linked with two or more different gene segments, and Type III spacer undefined. This study examined the diversity of CRISPR/cas system in Shigella strains, demonstrated the main features of CRISPR structure and spacer classification, which provided critical information for elucidation of the mechanisms of spacer formation and exploration of the role the spacers play in the function of the CRISPR/cas system.

  1. Identification of Western Equine Encephalitis Virus Structural Proteins That Confer Protection after DNA Vaccination▿

    PubMed Central

    Gauci, Penelope J.; Wu, Josh Q. H.; Rayner, George A.; Barabé, Nicole D.; Nagata, Leslie P.; Proll, David F.

    2010-01-01

    DNA vaccines encoding different portions of the structural proteins of western equine encephalitis virus were tested for the efficacy of their protection in a 100% lethal mouse model of the virus. The 6K-E1 structural protein encoded by the DNA vaccine conferred complete protection against challenge with the homologous strain and limited protection against challenge with a heterologous strain. PMID:19923571

  2. Journal Clubs and Case Conferences: From Academic Tradition to Communities of Practice

    ERIC Educational Resources Information Center

    Price, David W.; Felix, Kate G.

    2008-01-01

    Introduction: As small group learning sessions, Journal Clubs (JCs) and Case Conferences (CCs), if structured interactively, have potential as educational formats that can change practice. However, the degree to which these formats, as currently typically structured, lead to practice change is unknown. Methods: We used concepts of communities of…

  3. Modelling large deformation and soil—water—structure interaction with material point method: Briefing on MPM2017 conference

    NASA Astrophysics Data System (ADS)

    Rohe, Alexander; Liang, Dongfang

    2017-06-01

    The 1st International Conference on the Material Point Method for "Modelling Large Deformation and Soil-Water-Structure Interaction" (MPM2017) was held in Delft, The Netherlands on 10-13 January 2017. This is the first conference organised by the Anura3D MPM Research Community, following a series of international workshops and symposia previously held in The Netherlands, UK, Spain and Italy, as part of the European Commission FP7 Marie-Curie project MPM-DREDGE. We are delighted to present seven contributions in this Special Column of the Journal of Hydrodynamics, and take this opportunity to announce that the 2nd conference, MPM2019, will be held in Cambridge, UK in January 2019.

  4. Quark Matter 2017: Young Scientist Support

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Evdokimov, Olga

    Quark Matter conference series are amongst the major scientific events for the Relativistic Heavy Ion community. With over 30 year long history, the meetings are held about every 1½ years to showcase the progress made in theoretical and experimental studies of nuclear matter under extreme conditions. The 26th International Conference on Ultra-relativistic Nucleus-Nucleus Collisions (Quark Matter 2017) was held at the Hyatt Regency Hotel in downtown Chicago from Sunday, February 5th through Saturday, February 11th, 2017. The conference featured about 180 plenary and parallel presentations of the most significant recent results in the field, a poster session for additional presentations,more » and an evening public lecture. Following the tradition of previous Quark Matter meetings, the first day of the conference was dedicated entirely to a special program for young scientists (graduate students and postdoctoral researchers). This grant will provided financial support for 235 young physicists facilitating their attendance of the conference.« less

  5. PREFACE: 13th Anglo-French Physical Acoustics Conference (AFPAC2014)

    NASA Astrophysics Data System (ADS)

    Gélat, Pierre; Pinfield, Valerie; Cegla, Frederic; Saffari, Nader; Lhémery, Alain

    2015-01-01

    The 13th Anglo-French Physical Acoustics Conference (AFPAC) was held at Selsdon Park Hotel, Croydon near London, United Kingdom, on 15-17 January 2014. The venue was an excellent location to exchange ideas, regardless whether this happened in the conference room, over lunch at the drinks reception in the conservatory, in the oak panelled bar after the conference dinner or in the local pub next door. Over 45 papers were presented at the conference. There were over 60 delegates from institutions covering four countries. The invited speakers from the French side shared their knowledge about the generation of sound from supersonic jets (Prof Christophe Bailly, École Centrale de Lyon) and the application of ultrasonic microscropy in the nuclear industry (Prof Gilles Despaux, Université de Montpellier). The UK invited speakers included Prof Malcolm Povey (University of Leeds), who talked about characterisation of the nucleation of crystals using ultrasound, and Prof Bruce Drinkwater (University of Bristol), who captured the audience by speaking about "ultrasonic lassos" and ultrasonic particle manipulation. There was a strong representation of laser ultrasonics at the meeting with scientific considerations of problems and applications that range from the macro to the nanoscale. There were also numerous papers on the interaction of elastic and acoustic waves with complex materials and scattering of these waves by materials such as foams or cavitating liquids. Presentations on biomedical applications are increasingly being featured at AFPAC meetings. Talks this year covered topics such as imaging and high-intensity focused ultrasound for therapeutic applications. Finally, there were also several contributions from the field of Non-Destructive Evaluation (NDE) and Structural Health Monitoring (SHM) with talks ranging from the determination of the properties of in vivo wood to ultrasonic scattering techniques and tomographic reconstructions to recover the size and shape of defects in pipes and plates. The UK organising committee was particularly happy to welcome the many French contributors that travelled to Croydon and would like to thank Alain Lhémery and the Société Française d'Acoustique (SFA) for publicising the event in France. We are happy to announce that many of the presented papers will be published in the conference proceedings in Journal of Physics: Conference Series. We would also like to draw the reader's attention to the upcoming 14th AFPAC conference that is scheduled to take place on 14-16 of January 2015 in Fréjus, France.

  6. Co-Conserved MAPK Features Couple D-Domain Docking Groove to Distal Allosteric Sites via the C-Terminal Flanking Tail

    PubMed Central

    Nguyen, Tuan; Ruan, Zheng; Oruganty, Krishnadev; Kannan, Natarajan

    2015-01-01

    Mitogen activated protein kinases (MAPKs) form a closely related family of kinases that control critical pathways associated with cell growth and survival. Although MAPKs have been extensively characterized at the biochemical, cellular, and structural level, an integrated evolutionary understanding of how MAPKs differ from other closely related protein kinases is currently lacking. Here, we perform statistical sequence comparisons of MAPKs and related protein kinases to identify sequence and structural features associated with MAPK functional divergence. We show, for the first time, that virtually all MAPK-distinguishing sequence features, including an unappreciated short insert segment in the β4-β5 loop, physically couple distal functional sites in the kinase domain to the D-domain peptide docking groove via the C-terminal flanking tail (C-tail). The coupling mediated by MAPK-specific residues confers an allosteric regulatory mechanism unique to MAPKs. In particular, the regulatory αC-helix conformation is controlled by a MAPK-conserved salt bridge interaction between an arginine in the αC-helix and an acidic residue in the C-tail. The salt-bridge interaction is modulated in unique ways in individual sub-families to achieve regulatory specificity. Our study is consistent with a model in which the C-tail co-evolved with the D-domain docking site to allosterically control MAPK activity. Our study provides testable mechanistic hypotheses for biochemical characterization of MAPK-conserved residues and new avenues for the design of allosteric MAPK inhibitors. PMID:25799139

  7. KSC-99pp1215

    NASA Image and Video Library

    1999-10-14

    Seen from above, construction of a new site at KSC's Visitor Complex, The Early Space Exploration and Conference Center, is nearly finished. It is expected to be open to the public by mid-November. The space exploration facility will feature Mercury and Gemini capsules and the recently relocated Mission Control Center. Attached to it is a state-of-the-art conference center. Built by Delaware North Park Services, the facility is located between the Rock Garden and the Center for Space Education

  8. Precise Dimensions; A history of units from 1791-2018

    NASA Astrophysics Data System (ADS)

    Cooper, Malcolm; Grozier, Jim

    2017-11-01

    Units are the foundation for all measurement of the natural world, and from which standard, our understanding develops. This book, stemming from a conference on the history of units organised by the editors, provides a detailed and discursive examination of the history of units within physics, in advance of the proposed redefinition of the SI base units at the General Conference on Weights and Measures in 2018. It features contributions from leading researchers in metrology and history.

  9. Seventh annual National Conference of Black Physics students. Summary report, February 12--13, 1993

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    The 1993 conference hosted a wide variety of presentations and activities. Continuing the NCBPS tradition, we offered technical physics presentations, tours of physics research facilities, a career and educational fair, technical presentations by students, dinner speakers and a dance. New this, year were the interactive workshops (described in the section entitled ``New Features``). We included a ``celebrity`` speaker -- Col. Fred Gregory, an African-American NASA astronaut This presentation was featured on the local TV news. There were two last minute changes to the program They included: the replacement of Howard Adams and Tim Childs with Sylvia Wilson and Warren Buck,more » respectively. Howard Adams was ill and canceled a couple of days in advance. He recommended Sylvia Wilson, also of the GEM Program, as a replacement speaker. The substitution worked quite well, especially since our program was lacking in female speakers. Tim Childs missed his flight so Warren Buck, who attended the conference as an observer, generously filled in at the last minute. We ran a brief survey of the corporate, governmental and educational recruiters who were part of our Career/Educational Fair. Of 15 recruiters, 9 responded to the survey. All who responded said they were pleased with the conference arrangements. See Appendix C for the complete results of the Survey for Recruiters.« less

  10. Survey of Computer-Based Message Systems; COM/PortaCOM Conference System: Design Goals and Principles; Computer Conferencing Is More Than Electronic Mail; Effects of the COM Computer Conference System.

    ERIC Educational Resources Information Center

    Palme, Jacob

    The four papers contained in this document provide: (1) a survey of computer based mail and conference systems; (2) an evaluation of systems for both individually addressed mail and group addressing through conferences and distribution lists; (3) a discussion of various methods of structuring the text data in existing systems; and (4) a…

  11. CEE in DC: Tracings of a Conference Experiment and the Questions They Raise.

    ERIC Educational Resources Information Center

    Christenbury, Leila; Newman, Judith M.

    1993-01-01

    Describes the changes made in the traditional structure of the conference format as instituted at the 1992 Conference on English Education in Washington, DC. Outlines the methods by which feedback and criticism by participants were solicited, analyzed, and evaluated. Discusses conclusions based on the data gathered. (HB)

  12. Argumentation in a Multi Party Asynchronous Computer Mediated Conference: A Generic Analysis

    ERIC Educational Resources Information Center

    Coffin, Caroline; Painter, Clare; Hewings, Ann

    2005-01-01

    This paper draws on systemic functional linguistic genre analysis to illuminate the way in which post graduate applied linguistics students structure their argumentation within a multi party asynchronous computer mediated conference. Two conference discussions within the same postgraduate course are compared in order to reveal the way in which…

  13. Discovering rules for protein-ligand specificity using support vector inductive logic programming.

    PubMed

    Kelley, Lawrence A; Shrimpton, Paul J; Muggleton, Stephen H; Sternberg, Michael J E

    2009-09-01

    Structural genomics initiatives are rapidly generating vast numbers of protein structures. Comparative modelling is also capable of producing accurate structural models for many protein sequences. However, for many of the known structures, functions are not yet determined, and in many modelling tasks, an accurate structural model does not necessarily tell us about function. Thus, there is a pressing need for high-throughput methods for determining function from structure. The spatial arrangement of key amino acids in a folded protein, on the surface or buried in clefts, is often the determinants of its biological function. A central aim of molecular biology is to understand the relationship between such substructures or surfaces and biological function, leading both to function prediction and to function design. We present a new general method for discovering the features of binding pockets that confer specificity for particular ligands. Using a recently developed machine-learning technique which couples the rule-discovery approach of inductive logic programming with the statistical learning power of support vector machines, we are able to discriminate, with high precision (90%) and recall (86%) between pockets that bind FAD and those that bind NAD on a large benchmark set given only the geometry and composition of the backbone of the binding pocket without the use of docking. In addition, we learn rules governing this specificity which can feed into protein functional design protocols. An analysis of the rules found suggests that key features of the binding pocket may be tied to conformational freedom in the ligand. The representation is sufficiently general to be applicable to any discriminatory binding problem. All programs and data sets are freely available to non-commercial users at http://www.sbg.bio.ic.ac.uk/svilp_ligand/.

  14. Innovations in vaccine development: can regulatory authorities keep up?

    PubMed

    Cox, Manon M J; Onraedt, Annelies

    2012-10-01

    Vaccine Production Summit San Francisco, CA, USA, 4-6 June 2012 IBC's 3rd Vaccine Production Summit featured 28 presentations discussing regulatory challenges in vaccine development, including the use of adjuvants, vaccine manufacturing and technology transfer, process development for vaccines and the role of quality by design, how to address vaccine stability, and how vaccine development timelines can be improved. The conference was run in parallel with the single-use applications for Biopharmaceutical Manufacturing conference. Approximately 250 attendees from large pharmaceutical companies, large and small biotech companies, vendors and a more limited number from academia were allowed to access sessions of either conference, including one shared session. This article summarizes the recurring themes across various presentations.

  15. On the contributions of topological features to transcriptional regulatory network robustness

    PubMed Central

    2012-01-01

    Background Because biological networks exhibit a high-degree of robustness, a systemic understanding of their architecture and function requires an appraisal of the network design principles that confer robustness. In this project, we conduct a computational study of the contribution of three degree-based topological properties (transcription factor-target ratio, degree distribution, cross-talk suppression) and their combinations on the robustness of transcriptional regulatory networks. We seek to quantify the relative degree of robustness conferred by each property (and combination) and also to determine the extent to which these properties alone can explain the robustness observed in transcriptional networks. Results To study individual properties and their combinations, we generated synthetic, random networks that retained one or more of the three properties with values derived from either the yeast or E. coli gene regulatory networks. Robustness of these networks were estimated through simulation. Our results indicate that the combination of the three properties we considered explains the majority of the structural robustness observed in the real transcriptional networks. Surprisingly, scale-free degree distribution is, overall, a minor contributor to robustness. Instead, most robustness is gained through topological features that limit the complexity of the overall network and increase the transcription factor subnetwork sparsity. Conclusions Our work demonstrates that (i) different types of robustness are implemented by different topological aspects of the network and (ii) size and sparsity of the transcription factor subnetwork play an important role for robustness induction. Our results are conserved across yeast and E Coli, which suggests that the design principles examined are present within an array of living systems. PMID:23194062

  16. Molecular characterization of the staphylococcal multidrug resistance export protein QacC.

    PubMed Central

    Paulsen, I T; Brown, M H; Dunstan, S J; Skurray, R A

    1995-01-01

    The QacC polypeptide is a member of a family of small membrane proteins which confer resistance to toxic compounds. The staphylococcal qacC gene confers resistance to toxic organic cations via proton-dependent export. The membrane topology of the QacC polypeptide was investigated by constructing and analyzing a series of qacC-phoA and qacC-lacZ fusions. From these analyses, most of the predicted features of the QacC protein were verified, although data regarding the possible orientation of the COOH region were not conclusive. The role of the sole cysteine residue, Cys-42, in QacC was studied by using the sulfhydryl reagent N-ethylmaleimide and site-directed mutagenesis. N-Ethylmaleimide was shown to inhibit qacC-mediated ethidium export. Multiple amino acid substitutions were made for Cys-42, and mutations at this location had various effects on resistance specificity. This suggests that the Cys-42 residue may be located near a region of QacC that is involved in substrate recognition. Mutagenesis of conserved residues in QacC indicated that Tyr-59 and Trp-62 also play an essential structural or functional role in QacC. PMID:7751293

  17. With the Design in Mind: "High School Reform Model Features That Matter in Implementation." Conference Paper

    ERIC Educational Resources Information Center

    Shiffman, Catherine Dunn

    2015-01-01

    This paper proposes a framework for analyzing program design features that seem to matter in implementation. The framework is based on findings from a study conducted by the Consortium for Policy Research in Education (CPRE) between 2004 and 2007 that explored how reform ideas and practices created by five external provider organizations were…

  18. Voltage Sensing in Membranes: From Macroscopic Currents to Molecular Motions.

    PubMed

    Freites, J Alfredo; Tobias, Douglas J

    2015-06-01

    Voltage-sensing domains (VSDs) are integral membrane protein units that sense changes in membrane electric potential, and through the resulting conformational changes, regulate a specific function. VSDs confer voltage-sensitivity to a large superfamily of membrane proteins that includes voltage-gated Na[Formula: see text], K[Formula: see text], Ca[Formula: see text] ,and H[Formula: see text] selective channels, hyperpolarization-activated cyclic nucleotide-gated channels, and voltage-sensing phosphatases. VSDs consist of four transmembrane segments (termed S1 through S4). Their most salient structural feature is the highly conserved positions for charged residues in their sequences. S4 exhibits at least three conserved triplet repeats composed of one basic residue (mostly arginine) followed by two hydrophobic residues. These S4 basic side chains participate in a state-dependent internal salt-bridge network with at least four acidic residues in S1-S3. The signature of voltage-dependent activation in electrophysiology experiments is a transient current (termed gating or sensing current) upon a change in applied membrane potential as the basic side chains in S4 move across the membrane electric field. Thus, the unique structural features of the VSD architecture allow for competing requirements: maintaining a series of stable transmembrane conformations, while allowing charge motion, as briefly reviewed here.

  19. Recent advances of pyrrolopyridines derivatives: a patent and literature review.

    PubMed

    El-Gamal, Mohammed I; Anbar, Hanan S

    2017-05-01

    Several pyrrolopyridines or azaindoles have been reported in the literature as biologically-active molecules. Most of them are anticancer agents, and few possess other therapeutic effects. Areas covered: The most recent biologically-active pyrrolopyridine derivatives have been reviewed from the patents and research articles published from 2010 to the mid of 2016. Their structural and biological features have been explained. In general, the pyrrolopyridine scaffold mimics the purine ring of the ATP molecule. So the well-designed pyrrolopyridine analogues can successfully act as kinase inhibitors for treatment of cancer and/or other diseases. The most successful pyrrolopyridine derivative that is currently used in the market is vemurafenib, which is used for treatment of melanoma. Its chemical and biological features have been reviewed and explained. Expert opinion: The heterocyclic pyrrolopyridine nucleus mimics the purine ring of ATP. So they can work as inhibitors of the kinase at hinge region. Due to the structural similarity with ATP, these pyrrolopyridine derivatives are estimated to be non-selective kinase inhibitors. The selectivity is conferred mainly from the different substituents attached to the azaindole nucleus. More details are presented in the 'Expert Opinion' section at the end of this article. This section covers the chemistry and the biological properties of therapeutically-efficient pyrrolopyridine-possessing compounds.

  20. New Insights into the In Silico Prediction of HIV Protease Resistance to Nelfinavir

    PubMed Central

    Antunes, Dinler A.; Rigo, Maurício M.; Sinigaglia, Marialva; de Medeiros, Rúbia M.; Junqueira, Dennis M.; Almeida, Sabrina E. M.; Vieira, Gustavo F.

    2014-01-01

    The Human Immunodeficiency Virus type 1 protease enzyme (HIV-1 PR) is one of the most important targets of antiretroviral therapy used in the treatment of AIDS patients. The success of protease-inhibitors (PIs), however, is often limited by the emergence of protease mutations that can confer resistance to a specific drug, or even to multiple PIs. In the present study, we used bioinformatics tools to evaluate the impact of the unusual mutations D30V and V32E over the dynamics of the PR-Nelfinavir complex, considering that codons involved in these mutations were previously related to major drug resistance to Nelfinavir. Both studied mutations presented structural features that indicate resistance to Nelfinavir, each one with a different impact over the interaction with the drug. The D30V mutation triggered a subtle change in the PR structure, which was also observed for the well-known Nelfinavir resistance mutation D30N, while the V32E exchange presented a much more dramatic impact over the PR flap dynamics. Moreover, our in silico approach was also able to describe different binding modes of the drug when bound to different proteases, identifying specific features of HIV-1 subtype B and subtype C proteases. PMID:24498124

  1. Light Scattering by Nonspherical Particles

    NASA Technical Reports Server (NTRS)

    Mishchenko, Michael I.; Travis, Larry D.; Hovenier, Joop W.

    1998-01-01

    Improved understanding of electromagnetic scattering by nonspherical particles is important to many science and engineering disciplines and was the subject of the Conference on Light Scattering by Nonspherical Particles: Theory, Measurements, and Applications. The conference was held 29 September-1 October 1998 at the Goddard Institute for Space Studies in New York City and brought together 115 participants from 18 countries. The main objective of the conference was to highlight and summarize the rapid advancements in the field, including numerical methods for computing the single and multiple scattering of electromagnetic radiation by nonspherical and heterogeneous particles, measurement approaches, knowledge of characteristic features in scattering patterns, retrieval and remote sensing techniques, nonspherical particle sizing, and various practical applications. The conference consisted of twelve oral and one poster sessions. The presentations were loosely grouped based on broad topical categories. In each of these categories invited review talks highlighted and summarized specific active areas of research. To ensure a high-quality conference, all abstracts submitted had been reviewed by members of the Scientific Organizing Committee for technical merit and content. The conference program was published in the June 1998 issue of the Bulletin of the American Meteorological Society and is available on the World Wide Web at http://www.giss.nasa.gov/-crmim/conference/program.html. Authors of accepted papers and review presentations contributed to a volume of preprints published by the American Meteorological Society' and distributed to participants at the conference.

  2. Biomedical informatics publications: a global perspective: part I: conferences.

    PubMed

    Maojo, V; García-Remesal, M; Bielza, C; Crespo, J; Perez-Rey, D; Kulikowski, C

    2012-01-01

    In the past decade, Medical Informatics (MI) and Bioinformatics (BI) have converged towards a new discipline, called Biomedical Informatics (BMI) bridging informatics methods across the spectrum from genomic research to personalized medicine and global healthcare. This convergence still raises challenging research questions which are being addressed by researchers internationally, which in turn raises the question of how biomedical informatics publications reflect the contributions from around the world in documenting the research. To analyse the worldwide participation of biomedical informatics researchers from professional groups and societies in the best-known scientific conferences in the field. The analysis is focused on their geographical affiliation, but also includes other features, such as the impact and recognition of the conferences. We manually collected data about authors of papers presented at three major MI conferences: Medinfo, MIE and the AMIA symposium. In addition, we collected data from a BI conference, ISMB, as a comparison. Finally, we analyzed the impact and recognition of these conferences within their scientific contexts. Data indicate a predominance of local authors at the regional conferences (AMIA and MIE), whereas other conferences with a world-wide scope (Medinfo and ISMB) had broader participation. Our analysis shows that the influence of these conferences beyond the discipline remains somewhat limited. Our results suggest that for BMI to be recognized as a broad discipline, both in the geographical and scientific sense, it will need to extend the scope of collaborations and their interdisciplinary impacts worldwide.

  3. 2011 Dynamics at Surfaces Gordon Research Conference (August 7-12, 2011, Salve Regina University, Newport, Rhode Island)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Greg Sitz

    2011-08-12

    The 2011 Gordon Conference on Dynamics at Surfaces is the 32nd anniversary of a meeting held every two years that is attended by leading researchers in the area of experimental and theoretical dynamics at liquid and solid surfaces. The conference focuses on the dynamics of the interaction of molecules with either liquid or solid surfaces, the dynamics of the outermost layer of liquid and solid surfaces and the dynamics at the liquid-solid interface. Specific topics that are featured include state-to-state scattering dynamics, chemical reaction dynamics, non-adiabatic effects in reactive and inelastic scattering of molecules from surfaces, single molecule dynamics atmore » surfaces, surface photochemistry, ultrafast dynamics at surfaces, and dynamics at water interfaces. The conference brings together investigators from a variety of scientific disciplines including chemistry, physics, materials science, geology, biophysics, and astronomy.« less

  4. 13th ERS Lung Science Conference. The most important take home messages: News from the Underground.

    PubMed

    Bikov, Andras; Boots, Agnes; Bjerg, Anders; Jacinto, Tiago; Olland, Anne; Skoczyński, Szymon

    2015-06-01

    The 13th ERS Lung Science Conference (LSC) was organised to bring academics together from all over the world to present and discuss the latest developments regarding lung infection and immunity. The conference took place in breathtaking Estoril, Portugal; however, it wasn't the beautiful surroundings that were our main motivation to attend, but instead the scientific merit of the conference and the chance to create new scientific collaborations. The scientific programme [1] was packed with the most up-to-date content in the field of lung infection and immunity and included some of the top researchers within this exciting area. Moreover, the convenient size of the LSC offered the opportunity to renew and intensify friendships and collaborations. In particular, for researchers at the start of their career, this is a great feature and we therefore warmly recommend the LSC to ERS Juniors Members!

  5. Conference report from International Congress on Infectious Diseases 2014: part 2.

    PubMed

    McLoughlin, Hilda

    2014-01-01

    This second and final instalment of the conference report from International Congress on Infectious Diseases 2014 follows on from part one, published in Future Microbiology (volume 9/issue 11). The 16th International Congress on Infectious Diseases was held in Cape Town this year, marking the return of the conference to Africa for the first time in 22 years. While infectious diseases such as malaria, tuberculosis and HIV--all still prevalent in the African healthcare landscape--dominated the program, the conference featured several important sessions on fungal infection and a significant number of posters devoted to this critical medical area. Within the context of the rise of antimicrobial resistance, now identified by WHO as one of the three greatest threats to human health, came the message that resistance is not limited to antimicrobials, but that antifungal resistance is also a significant and emerging threat worldwide.

  6. State of Wisconsin Evaluation Conference Summary: ESEA Title I Migrant Education Programs, Summer of 1979.

    ERIC Educational Resources Information Center

    Wisconsin State Dept. of Public Instruction, Madison. Div. for Management and Planning Services.

    The Elementary Secondary Education Act Title I Wisconsin Migrant Education Conference was held on August 6, 1979 to evaluate programs and to gather program planning data. Data for this evaluation were collected by means of both structured interaction of the 53 conference participants and questionnaires completed by participants. The teachers felt…

  7. The Structure of Knowledge. A Feminist Perspective. Proceedings of the Annual GLCA Women's Studies Conference (4th, November 10-12, 1978).

    ERIC Educational Resources Information Center

    Reed, Beth, Ed.; And Others

    A keynote address, five selected conference papers, and two panel discussions are presented in these conference proceedings. The keynote address, "Breaking the Disciplines" (Florence Howe), examines the development of traditional disciplines as the mainstream of higher education's curriculum and the omission of women from these…

  8. Guidance and control, 1993; Annual Rocky Mountain Guidance and Control Conference, 16th, Keystone, CO, Feb. 6-10, 1993

    NASA Astrophysics Data System (ADS)

    Culp, Robert D.; Bickley, George

    Papers from the sixteenth annual American Astronautical Society Rocky Mountain Guidance and Control Conference are presented. The topics covered include the following: advances in guidance, navigation, and control; control system videos; guidance, navigation and control embedded flight control systems; recent experiences; guidance and control storyboard displays; and applications of modern control, featuring the Hubble Space Telescope (HST) performance enhancement study. For individual titles, see A95-80390 through A95-80436.

  9. Aerial view of a new site at KSC's Visitor Complex

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Seen from above, construction of a new site at KSC's Visitor Complex, The Early Space Exploration and Conference Center, is nearly finished. It is expected to be open to the public by mid- November. The space exploration facility will feature Mercury and Gemini capsules and the recently relocated Mission Control Center. Attached to it is a state-of-the-art conference center. Built by Delaware North Park Services, the facility is located between the Rock Garden and the Center for Space Education.

  10. Proceedings of the Second All-USGS Modeling Conference, February 11-14, 2008: Painting the Big Picture

    USGS Publications Warehouse

    Brady, Shailaja R.

    2009-01-01

    The Second USGS Modeling Conference was held February 11-14, 2008, in Orange Beach, Ala. Participants at the conference came from all U.S. Geological Survey (USGS) regions and represented all four science discipline - Biology, Geography, Geology, and Water. Representatives from other Department of the Interior (DOI) agencies and partners from the academic community also participated. The conference, which was focused on 'painting the big picture', emphasized the following themes: Integrated Landscape Monitoring, Global Climate Change, Ecosystem Modeling, and Hazards and Risks. The conference centered on providing a forum for modelers to meet, exchange information on current approaches, identify specific opportunities to share existing models and develop more linked and integrated models to address complex science questions, and increase collaboration across disciplines and with other organizations. Abstracts for the 31 oral presentations and more than 60 posters presented at the conference are included here. The conference also featured a field trip to review scientific modeling issues along the Gulf of Mexico. The field trip included visits to Mississippi Sandhill Crane National Wildlife Refuge, Grand Bay National Estuarine Research Reserve, the 5 Rivers Delta Resource Center, and Bon Secour National Wildlife Refuge. On behalf of all the participants of the Second All-USGS Modeling Conference, the conference organizing committee expresses our sincere appreciation for the support of field trip oganizers and leaders, including the managers from the various Reserves and Refuges. The organizing committee for the conference included Jenifer Bracewell, Sally Brady, Jacoby Carter, Thomas Casadevall, Linda Gundersen, Tom Gunther, Heather Henkel, Lauren Hay, Pat Jellison, K. Bruce Jones, Kenneth Odom, and Mark Wildhaber.

  11. Leveraging a Redesigned Morbidity and Mortality Conference That Incorporates the Clinical and Educational Missions of Improving Quality and Patient Safety.

    PubMed

    Tad-Y, Darlene B; Pierce, Read G; Pell, Jonathan M; Stephan, Lindsie; Kneeland, Patrick P; Wald, Heidi L

    2016-09-01

    The morbidity and mortality (M&M) conference is a vital event that can affect medical education, quality improvement, and peer review in academic departments. Historically, M&M conferences have emphasized cases that highlight diagnostic uncertainty or complex management conundrums. In this report, the authors describe the development, pilot, and refinement of a systems-based M&M conference model that combines the educational and clinical missions of improving quality and patient safety in the University of Colorado Department of Medicine. In 2011, a focused taskforce completed a literature review that informed the development of a framework for the redesigned systems-based M&M conference. The new model included a restructured monthly conference, longitudinal curriculum for residents, and formal channels for interaction with clinical effectiveness departments. Each conference features an in-depth discussion of an adverse event using specific quality improvement tools. Areas for improvement and suggested action items are identified during the conference and delegated to the relevant clinical departments. The new process has enabled the review of 27 adverse events over two years. Sixty-three action items were identified, and 33 were pursued. An average of 50 to 60 individuals participate in each conference, including interprofessional and interdisciplinary colleagues. Resident and faculty feedback regarding the new format has been positive, and other departments are starting to adopt this model. A more robust process for identifying and selecting cases to discuss is needed, as is a stable, sufficient mechanism to manage the improvement initiatives that come out of each conference.

  12. Self-assembly with orthogonal-imposed stimuli to impart structure and confer magnetic function to electrodeposited hydrogels.

    PubMed

    Li, Ying; Liu, Yi; Gao, Tieren; Zhang, Boce; Song, Yingying; Terrell, Jessica L; Barber, Nathan; Bentley, William E; Takeuchi, Ichiro; Payne, Gregory F; Wang, Qin

    2015-05-20

    A magnetic nanocomposite film with the capability of reversibly collecting functionalized magnetic particles was fabricated by simultaneously imposing two orthogonal stimuli (electrical and magnetic). We demonstrate that cathodic codeposition of chitosan and Fe3O4 nanoparticles while simultaneously applying a magnetic field during codeposition can (i) organize structure, (ii) confer magnetic properties, and (iii) yield magnetic films that can perform reversible collection/assembly functions. The magnetic field triggered the self-assembly of Fe3O4 nanoparticles into hierarchical "chains" and "fibers" in the chitosan film. For controlled magnetic properties, the Fe3O4-chitosan film was electrodeposited in the presence of various strength magnetic fields and different deposition times. The magnetic properties of the resulting films should enable broad applications in complex devices. As a proof of concept, we demonstrate the reversible capture and release of green fluorescent protein (EGFP)-conjugated magnetic microparticles by the magnetic chitosan film. Moreover, antibody-functionalized magnetic microparticles were applied to capture cells from a sample, and these cells were collected, analyzed, and released by the magnetic chitosan film, paving the way for applications such as reusable biosensor interfaces (e.g., for pathogen detection). To our knowledge, this is the first report to apply a magnetic field during the electrodeposition of a hydrogel to generate magnetic soft matter. Importantly, the simple, rapid, and reagentless fabrication methodologies demonstrated here are valuable features for creating a magnetic device interface.

  13. Tribal 319: 2010 NPS Workshop

    EPA Pesticide Factsheets

    This tribal training was offered during the first day of the National Water Quality Monitoring Council conference held in Denver, Colorado. The session covered CWA Section 106 and 319 topics, and featured three tribal case studies.

  14. Zebrafish hox paralogue group 2 genes function redundantly as selector genes to pattern the second pharyngeal arch.

    PubMed

    Hunter, Michael P; Prince, Victoria E

    2002-07-15

    The pharyngeal arches are one of the defining features of the vertebrates, with the first arch forming the mandibles of the jaw and the second forming jaw support structures. The cartilaginous elements of each arch are formed from separate migratory neural crest cell streams, which derive from the dorsal aspect of the neural tube. The second and more posterior crest streams are characterized by specific Hox gene expression. The zebrafish has a larger overall number of Hox genes than the tetrapod vertebrates, as the result of a duplication event in its lineage. However, in both zebrafish and mouse, there are just two members of Hox paralogue group 2 (PG2): Hoxa2 and Hoxb2. Here, we show that morpholino-mediated "knock-down" of both zebrafish Hox PG2 genes results in major defects in second pharyngeal arch cartilages, involving replacement of ventral elements with a mirror-image duplication of first arch structures, and accompanying changes to pharyngeal musculature. In the mouse, null mutants of Hoxa2 have revealed that this single Hox gene is required for normal second arch patterning. By contrast, loss-of-function of either zebrafish Hox PG2 gene individually has no phenotypic consequence, showing that these two genes function redundantly to confer proper pattern to the second pharyngeal arch. We have also used hoxb1a mis-expression to induce localized ectopic expression of zebrafish Hox PG2 genes in the first arch; using this strategy, we find that ectopic expression of either Hox PG2 gene can confer second arch identity onto first arch structures, suggesting that the zebrafish Hox PG2 genes act as "selector genes." 2002 Elsevier Science (USA).

  15. Role of the Conserved Disulfide Bridge in Class A Carbapenemases*

    PubMed Central

    Smith, Clyde A.; Nossoni, Zahra; Toth, Marta; Stewart, Nichole K.; Frase, Hilary; Vakulenko, Sergei B.

    2016-01-01

    Some members of the class A β-lactamase family are capable of conferring resistance to the last resort antibiotics, carbapenems. A unique structural feature of these clinically important enzymes, collectively referred to as class A carbapenemases, is a disulfide bridge between invariant Cys69 and Cys238 residues. It was proposed that this conserved disulfide bridge is responsible for their carbapenemase activity, but this has not yet been validated. Here we show that disruption of the disulfide bridge in the GES-5 carbapenemase by the C69G substitution results in only minor decreases in the conferred levels of resistance to the carbapenem imipenem and other β-lactams. Kinetic and circular dichroism experiments with C69G-GES-5 demonstrate that this small drop in antibiotic resistance is due to a decline in the enzyme activity caused by a marginal loss of its thermal stability. The atomic resolution crystal structure of C69G-GES-5 shows that two domains of this disulfide bridge-deficient enzyme are held together by an intensive hydrogen-bonding network. As a result, the protein architecture and imipenem binding mode remain unchanged. In contrast, the corresponding hydrogen-bonding networks in NMCA, SFC-1, and SME-1 carbapenemases are less intensive, and as a consequence, disruption of the disulfide bridge in these enzymes destabilizes them, which causes arrest of bacterial growth. Our results demonstrate that the disulfide bridge is essential for stability but does not play a direct role in the carbapenemase activity of the GES family of β-lactamases. This would likely apply to all other class A carbapenemases given the high degree of their structural similarity. PMID:27590339

  16. Role of the Conserved Disulfide Bridge in Class A Carbapenemases.

    PubMed

    Smith, Clyde A; Nossoni, Zahra; Toth, Marta; Stewart, Nichole K; Frase, Hilary; Vakulenko, Sergei B

    2016-10-14

    Some members of the class A β-lactamase family are capable of conferring resistance to the last resort antibiotics, carbapenems. A unique structural feature of these clinically important enzymes, collectively referred to as class A carbapenemases, is a disulfide bridge between invariant Cys 69 and Cys 238 residues. It was proposed that this conserved disulfide bridge is responsible for their carbapenemase activity, but this has not yet been validated. Here we show that disruption of the disulfide bridge in the GES-5 carbapenemase by the C69G substitution results in only minor decreases in the conferred levels of resistance to the carbapenem imipenem and other β-lactams. Kinetic and circular dichroism experiments with C69G-GES-5 demonstrate that this small drop in antibiotic resistance is due to a decline in the enzyme activity caused by a marginal loss of its thermal stability. The atomic resolution crystal structure of C69G-GES-5 shows that two domains of this disulfide bridge-deficient enzyme are held together by an intensive hydrogen-bonding network. As a result, the protein architecture and imipenem binding mode remain unchanged. In contrast, the corresponding hydrogen-bonding networks in NMCA, SFC-1, and SME-1 carbapenemases are less intensive, and as a consequence, disruption of the disulfide bridge in these enzymes destabilizes them, which causes arrest of bacterial growth. Our results demonstrate that the disulfide bridge is essential for stability but does not play a direct role in the carbapenemase activity of the GES family of β-lactamases. This would likely apply to all other class A carbapenemases given the high degree of their structural similarity. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  17. PREFACE: 11th International Conference on Damage Assessment of Structures (DAMAS 2015)

    NASA Astrophysics Data System (ADS)

    Wahab, M. A.

    2015-07-01

    This volume contains the proceedings of the 11th International Conference on Damage Assessment of Structures (DAMAS) 2015. DAMAS has a long history of almost 20 years. The first DAMAS conference took place in 1995 (Pescara, Italy), followed by a biannual meeting in 1997 (Sheffield, UK), 1999 (Dublin, Ireland), 2001 (Cardiff, UK), 2003 (Southampton, UK), 2005 (Gdansk, Poland), 2007 (Torino, Italy), 2009 (Beijing, China), 2011 (Oxford, UK) and 2013 (Dublin, Ireland). The eleventh edition of DAMAS conference series, DAMAS 2015, is hosted by Ghent University, Belgium, and is held at the congress center Het Pand in Ghent city. Ghent is the capital and the largest city of the East Flanders province of the Flemish region of Belgium. Het Pand is the culture and congress center of Ghent University and is a historical monument. The conference is established as a major international forum for research topics relevant to damage assessment of engineering structures and systems including numerical simulations, signal processing of sensor measurements and theoretical techniques as well as experimental case studies. The presentations of DAMAS 2015 are divided into 6 main sessions, namely 1) Structural Health and Condition Monitoring, 2) Damage in Civil Engineering, 3) Damage in Machineries, 4) Damage in Composite Materials, 5) Sensing and Sensors and 6) Signal Processing. The organising committee is grateful to keynote speakers; Professor Guido De Roeck, Head of Structural Mechanics Division, KULeuven, Belgium, for his keynote lecture entitled 'Structural Health Monitoring: highlights and challenges', Professor Weidong Zhu, Department of Mechanical Engineering, University of Maryland, USA, for his keynote lecture entitled 'Vibration-based Structural Damage Detection: Theory and Applications' and Professor Wieslaw Ostachowicz, Head of the Laboratory of Active Materials and Smart Structures, Polish Academy of Sciences, Poland, for his keynote lecture entitled 'Damage Assessment and Reliability in Offshore Wind Turbines Technology'. Special thanks go to members of the Scientific Committee of DAMAS 2015 for reviewing the articles published in this volume and for judging their scientific merits. Based on the comments of reviewers and the scientific merits of the submitted manuscripts, the articles were accepted for publication in the conference proceedings and for presentation at the conference venue. The accepted papers are of a very high scientific quality and contribute to advancement of knowledge in all research topics relevant to DAMAS conference. The organising committee would like to thank prestigious research groups, who made a great contribution to DAMAS 2015: the group of Professor Lars Damkilde, Aalborg University, Denmark; the group of professor Gilbert-Rainer Gillich, Eftimie Murgu University of resita, Romania, the group of Professor Wieslaw Ostachowicz, Polish Academy of Sciences, Poland and the group of Dr Vikram Pakrashi, University College Cork, Ireland. Special thanks go to Dr Vikram Pakrashi for organizing the mini-symposium 'Damage Detection, System Identification and Health Monitoring for Offshore Wind and Wave Energy Devices'. Finally, the organising committee would like to thank all authors, who have contributed to this volume and presented their research work at DAMAS 2015.

  18. Multispectral Analysis of NMR Imagery

    NASA Technical Reports Server (NTRS)

    Butterfield, R. L.; Vannier, M. W. And Associates; Jordan, D.

    1985-01-01

    Conference paper discusses initial efforts to adapt multispectral satellite-image analysis to nuclear magnetic resonance (NMR) scans of human body. Flexibility of these techniques makes it possible to present NMR data in variety of formats, including pseudocolor composite images of pathological internal features. Techniques do not have to be greatly modified from form in which used to produce satellite maps of such Earth features as water, rock, or foliage.

  19. Report on Wellesley Conference on Equal Pay and Equal Opportunity Policy in the United States, Canada, and Western Europe.

    ERIC Educational Resources Information Center

    Ratner, Ronnie Steinberg

    After a brief discussion of conference background and structure, these proceedings identify and summarize equal pay and employment policy issues discussed at a four-day working conference of sixty-five people from twelve advanced industrialized countries. Focus is on progress to date and alternative strategies for implementing policies. Strategies…

  20. Bibliography of Research in Natural Language Generation

    DTIC Science & Technology

    1993-11-01

    on 1397] Barbara J. Gross Focuing and description in Artifcial Intelligence (GWAI-88), Geseke, West natural language dialogues, In Joshi et al. (557...Proceedings of the Fifth Canadian Conference from information in a frame structure. Data and on Artificial Intelligence , pages Ŕ-24, London, Knowledge...generation workshops (IWNLGS, ENLGWS), natural language processing conferences (ANLP, TINLAP, SPEECH), artificial intelligence conferences (AAAI, SCA

  1. Proceedings of the international conference on cybernetics and societ

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1985-01-01

    This book presents the papers given at a conference on artificial intelligence, expert systems and knowledge bases. Topics considered at the conference included automating expert system development, modeling expert systems, causal maps, data covariances, robot vision, image processing, multiprocessors, parallel processing, VLSI structures, man-machine systems, human factors engineering, cognitive decision analysis, natural language, computerized control systems, and cybernetics.

  2. Proceedings of the Annual Adult Education Research Conference (23rd, Lincoln, Nebraska, April 1-3, 1982).

    ERIC Educational Resources Information Center

    Nebraska Univ., Lincoln. Dept. of Adult and Continuing Education.

    These proceedings of a conference on research in the field of adult education contain the texts of 40 conference papers and 4 symposia. Included among the areas examined in the individual reports are the following: education participation scale factor structure and correlates for 12,000 learners, a comparative analysis of adult education research…

  3. The material and biological characteristics of osteoinductive calcium phosphate ceramics

    PubMed Central

    Tang, Zhurong; Li, Xiangfeng; Tan, Yanfei

    2018-01-01

    Abstract The discovery of osteoinductivity of calcium phosphate (Ca-P) ceramics has set an enduring paradigm of conferring biological regenerative activity to materials with carefully designed structural characteristics. The unique phase composition and porous structural features of osteoinductive Ca-P ceramics allow it to interact with signaling molecules and extracellular matrices in the host system, creating a local environment conducive to new bone formation. Mounting evidence now indicate that the osteoinductive activity of Ca-P ceramics is linked to their physicochemical and three-dimensional structural properties. Inspired by this conceptual breakthrough, many laboratories have shown that other materials can be also enticed to join the rank of tissue-inducing biomaterials, and besides the bones, other tissues such as cartilage, nerves and blood vessels were also regenerated with the assistance of biomaterials. Here, we give a brief historical recount about the discovery of the osteoinductivity of Ca-P ceramics, summarize the underlying material factors and biological characteristics, and discuss the mechanism of osteoinduction concerning protein adsorption, and the interaction with different types of cells, and the involvement of the vascular and immune systems. PMID:29423267

  4. Does the Type of Event Influence How User Interactions Evolve on Twitter?

    PubMed Central

    del Val, Elena; Rebollo, Miguel; Botti, Vicente

    2015-01-01

    The number of people using on-line social networks as a new way of communication is continually increasing. The messages that a user writes in these networks and his/her interactions with other users leave a digital trace that is recorded. Thanks to this fact and the use of network theory, the analysis of messages, user interactions, and the complex structures that emerge is greatly facilitated. In addition, information generated in on-line social networks is labeled temporarily, which makes it possible to go a step further analyzing the dynamics of the interaction patterns. In this article, we present an analysis of the evolution of user interactions that take place in television, socio-political, conference, and keynote events on Twitter. Interactions have been modeled as networks that are annotated with the time markers. We study changes in the structural properties at both the network level and the node level. As a result of this analysis, we have detected patterns of network evolution and common structural features as well as differences among the events. PMID:25961305

  5. Report on IUPAP's International Conference on Women in Physics

    NASA Astrophysics Data System (ADS)

    Karplus Hartline, Beverly

    2002-03-01

    Teams of physicists from more than 60 countries are expected to participate in IUPAP's International Conference on Women in Physics in Paris, France from 7-9 March 2002. Discussions and resolutions will focus on (1) Attracting Girls into Physics, (2) Launching a Successful Physics Career, (3) Improving the Institutional Structure and Climate for Women in Physics, (4) Getting Women into the Power Structure of Physics, Nationally and Internationally, (5) Learning from Regional Differences, and (6) Balancing Family and Career. This talk will summarize the results and insights from the conference, with an emphasis on followup actions and strategies applicable to the United States.

  6. Transforming the Morbidity and Mortality Conference to Promote Safety and Quality in a PICU.

    PubMed

    Cifra, Christina L; Bembea, Melania M; Fackler, James C; Miller, Marlene R

    2016-01-01

    Determine the effectiveness of a structured systems-oriented morbidity and mortality conference in improving the process of reviewing and responding to adverse events in a PICU. Prospective time series analysis before and after implementation of a systems-oriented morbidity and mortality conference. Single tertiary referral PICU in Baltimore, MD. Thirty-three patients discussed before and 31 patients after implementation of a systems-oriented morbidity and mortality conference over a total of 20 morbidity and mortality conferences, from April 2013 to March 2014. Systems-oriented morbidity and mortality conference incorporating elements of medical incident analysis. There was a significant increase in meeting attendance (mean, 12 vs 31 attendees per morbidity and mortality conference; p < 0.001) after the systems-oriented morbidity and mortality conference was instituted. There was no significant difference in the mean number of cases suggested (4.2 vs 4.6) or discussed (3.3 vs 3.1) per morbidity and mortality conference. There was also no significant difference in the mean number of adverse events identified per morbidity and mortality conference (3.4 vs 4.3). However, there was an increase in the proportion of cases discussed using a standard case review tool, but this did not reach statistical significance (27% vs 45%; p = 0.231). Nevertheless, we observed a significant increase in the mean number of quality improvement interventions suggested (2.4 vs 5.6; p < 0.001) and implemented (1.7 vs 4.4; p < 0.001) per morbidity and mortality conference. All adverse event categories identified had corresponding interventions suggested after the systems-oriented morbidity and mortality conference was instituted compared with before (80% vs 100%). Intervention-to-adverse event ratios per category were also higher (mean, 0.6 vs 1.5). A structured systems-oriented PICU morbidity and mortality conference incorporating elements of medical incident analysis improves the process of reviewing and responding to adverse events by significantly increasing quality improvement interventions suggested and implemented. Future work would involve testing locally adapted versions of the systems-oriented morbidity and mortality conference in multiple inpatient settings.

  7. Mapping the coupled role of structure and materials in mechanics of platelet-matrix composites

    NASA Astrophysics Data System (ADS)

    Farzanian, Shafee; Shahsavari, Rouzbeh

    2018-03-01

    Despite significant progresses on understanding and mimicking the delicate nano/microstructure of biomaterials such as nacre, decoding the indistinguishable merger of materials and structures in controlling the tradeoff in mechanical properties has been long an engineering pursuit. Herein, we focus on an archetype platelet-matrix composite and perform ∼400 nonlinear finite element simulations to decode the complex interplay between various structural features and material characteristics in conferring the balance of mechanical properties. We study various combinatorial models expressed by four key dimensionless parameters, i.e. characteristic platelet length, matrix plasticity, platelet dissimilarity, and overlap offset, whose effects are all condensed in a new unifying parameter, defined as the multiplication of strength, toughness, and stiffness over composite volume. This parameter, which maximizes at a critical characteristic length, controls the transition from intrinsic toughening (matrix plasticity driven without crack growths) to extrinsic toughening phenomena involving progressive crack propagations. This finding, combined with various abstract volumetric and radar plots, will not only shed light on decoupling the complex role of structure and materials on mechanical performance and their trends, but provides important guidelines for designing lightweight staggered platelet-matrix composites while ensuring the best (balance) of their mechanical properties.

  8. Video conferencing made easy

    NASA Technical Reports Server (NTRS)

    Larsen, D. Gail; Schwieder, Paul R.

    1993-01-01

    Network video conferencing is advancing rapidly throughout the nation, and the Idaho National Engineering Laboratory (INEL), a Department of Energy (DOE) facility, is at the forefront of the development. Engineers at INEL/EG&G designed and installed a very unique DOE videoconferencing system, offering many outstanding features, that include true multipoint conferencing, user-friendly design and operation with no full-time operators required, and the potential for cost effective expansion of the system. One area where INEL/EG&G engineers made a significant contribution to video conferencing was in the development of effective, user-friendly, end station driven scheduling software. A PC at each user site is used to schedule conferences via a windows package. This software interface provides information to the users concerning conference availability, scheduling, initiation, and termination. The menus are 'mouse' controlled. Once a conference is scheduled, a workstation at the hubs monitors the network to initiate all scheduled conferences. No active operator participation is required once a user schedules a conference through the local PC; the workstation automatically initiates and terminates the conference as scheduled. As each conference is scheduled, hard copy notification is also printed at each participating site. Video conferencing is the wave of the future. The use of these user-friendly systems will save millions in lost productivity and travel cost throughout the nation. The ease of operation and conference scheduling will play a key role on the extent industry uses this new technology. The INEL/EG&G has developed a prototype scheduling system for both commercial and federal government use.

  9. When will I see you again? The fate of research findings from international wound care conferences*.

    PubMed

    Dumville, Jo C; Petherick, Emily S; Cullum, Nicky

    2008-03-01

    Medical conferences provide a forum for the rapid dissemination of research directly to health professionals and academics. However, the published record of poster and oral presentations from these meetings is usually limited to abstracts. We aimed to assess how many wound studies presented as conference abstracts were eventually published in journals and to identify the factors that predicted publication. The study was a retrospective review. We identified abstracts relating to oral and poster presentation from two large wound conferences. Following data extraction from the abstracts, a systematic search was conducted to examine if the research was subsequently published as a journal article. A time-to-event analysis was conducted to assess predictive associations between features of the research reported in the conference abstracts and time to full publication. In total, 492 abstracts from two European wound care conferences were identified (467 after exclusions). Of the abstracts included, 60% (279) were for posters and 40% (188) were for oral presentations. Over half of the abstracts (53%) reported results from case studies or case series design. In total, only 57 (12%) of the abstracts included resulted in a related publication. Analysis suggested that those studies reporting positive findings were significantly more likely to be published (hazard ratio 1.79, P= 0.001, 95% CIs 1.26-2.55). Few studies presented as conference abstracts at these two wounds conferences were subsequently published. This may be because of the low methodological quality of studies accepted for poster or oral presentation.

  10. Video conferencing made easy

    NASA Astrophysics Data System (ADS)

    Larsen, D. Gail; Schwieder, Paul R.

    1993-02-01

    Network video conferencing is advancing rapidly throughout the nation, and the Idaho National Engineering Laboratory (INEL), a Department of Energy (DOE) facility, is at the forefront of the development. Engineers at INEL/EG&G designed and installed a very unique DOE videoconferencing system, offering many outstanding features, that include true multipoint conferencing, user-friendly design and operation with no full-time operators required, and the potential for cost effective expansion of the system. One area where INEL/EG&G engineers made a significant contribution to video conferencing was in the development of effective, user-friendly, end station driven scheduling software. A PC at each user site is used to schedule conferences via a windows package. This software interface provides information to the users concerning conference availability, scheduling, initiation, and termination. The menus are 'mouse' controlled. Once a conference is scheduled, a workstation at the hubs monitors the network to initiate all scheduled conferences. No active operator participation is required once a user schedules a conference through the local PC; the workstation automatically initiates and terminates the conference as scheduled. As each conference is scheduled, hard copy notification is also printed at each participating site. Video conferencing is the wave of the future. The use of these user-friendly systems will save millions in lost productivity and travel cost throughout the nation. The ease of operation and conference scheduling will play a key role on the extent industry uses this new technology. The INEL/EG&G has developed a prototype scheduling system for both commercial and federal government use.

  11. Video conferencing made easy

    NASA Astrophysics Data System (ADS)

    Larsen, D. G.; Schwieder, P. R.

    Network video conferencing is advancing rapidly throughout the nation, and the Idaho National Engineering Laboratory (INEL), a Department of Energy (DOE) facility, is at the forefront of the development. Engineers at INEL/EG&G designed and installed a very unique DOE video conferencing system, offering many outstanding features, that include true multipoint conferencing, user-friendly design and operation with no full-time operators required, and the potential for cost effective expansion of the system. One area where INEL/EG&G engineers made a significant contribution to video conferencing was in the development of effective, user-friendly, end station driven scheduling software. A PC at each user site is used to schedule conferences via a windows package. This software interface provides information to the users concerning conference availability, scheduling, initiation, and termination. The menus are 'mouse' controlled. Once a conference is scheduled, a workstation at the hub monitors the network to initiate all scheduled conferences. No active operator participation is required once a user schedules a conference through the local PC; the workstation automatically initiates and terminates the conference as scheduled. As each conference is scheduled, hard copy notification is also printed at each participating site. Video conferencing is the wave of the future. The use of these user-friendly systems will save millions in lost productivity and travel costs throughout the nation. The ease of operation and conference scheduling will play a key role on the extent industry uses this new technology. The INEL/EG&G has developed a prototype scheduling system for both commercial and federal government use.

  12. The Way Forward: Women in Higher Education Management in Australia. Report of a National Conference (Armidale, New South Wales, Australia, July 18-20, 1984).

    ERIC Educational Resources Information Center

    Randell, Shirley, Ed.

    Issues concerning the participation of women in college administration in Australia are presented in this conference report. Of concern were structural and attitudinal barriers to greater participation of women in educational management and the role of government in fostering equal opportunity. Included are an overview of the conference,…

  13. Cardiovascular problems associated with aviation safety.

    DOT National Transportation Integrated Search

    1976-01-01

    In April 1975, the American College of Cardiology held its Eighth Bethesda Conference Conference on Cardiovascular Problem in Aviation Safety. : Perhaps the most meaningful purpose of this meeting was to make clear, in a structured fashion, the avail...

  14. 6th International Conference on Nanomaterials by Severe Plastic Deformation (NanoSPD6)

    NASA Astrophysics Data System (ADS)

    2014-08-01

    ''NanoSPD'' means Nano-material by Severe Plastic Deformation (SPD), which is an efficient way to obtain bulk nano-structured materials. During SPD, the microstructure of the material is transformed into a very fine structure consisting of ultra fine grains (UFG) approaching even the nano-scale. SPD is different from classical large strain forming processes in two aspects: 1. The sample undergoes extremely large strains without significant change in its dimensions, 2. In most SPD processes high hydrostatic stress is applied which makes it possible to deform difficult-to-form materials. This conference is part of a series of conferences taking place every third year; the history of NanoSPD conferences began in 1999 in Moscow (Russia), followed by Vienna in 2002 (Austria), Fukuoka in 2005 (Japan), Goslar in 2008 (Germany), Nanjing in 2011 (China), and Metz in 2014 (France). The preface continues in the pdf.

  15. Seals/Secondary Fluid Flows Workshop 1997; Volume I

    NASA Technical Reports Server (NTRS)

    Hendricks, Robert C. (Editor)

    2006-01-01

    The 1997 Conference provided discussions and data on (a) program overviews, (b) developments in seals and secondary air management systems, (c) interactive seals flows with secondary air or fluid flows and powerstream flows, (d) views of engine externals and limitations, (e) high speed engine research sealing needs and demands, and (f) a short course on engine design development margins. Sealing concepts discussed include, mechanical rim and cavity seals, leaf, finger, air/oil, rope, floating-brush, floating-T-buffer, and brush seals. Engine externals include all components of engine fluid systems, sensors and their support structures that lie within or project through the nacelle. The clean features of the nacelle belie the minefield of challenges and opportunities that lie within. Seals; Secondary air flows; Rotordynamics; Gas turbine; Aircraft; CFD; Testing; Turbomachinery

  16. A saponin-detoxifying enzyme mediates suppression of plant defences

    NASA Astrophysics Data System (ADS)

    Bouarab, K.; Melton, R.; Peart, J.; Baulcombe, D.; Osbourn, A.

    2002-08-01

    Plant disease resistance can be conferred by constitutive features such as structural barriers or preformed antimicrobial secondary metabolites. Additional defence mechanisms are activated in response to pathogen attack and include localized cell death (the hypersensitive response). Pathogens use different strategies to counter constitutive and induced plant defences, including degradation of preformed antimicrobial compounds and the production of molecules that suppress induced plant defences. Here we present evidence for a two-component process in which a fungal pathogen subverts the preformed antimicrobial compounds of its host and uses them to interfere with induced defence responses. Antimicrobial saponins are first hydrolysed by a fungal saponin-detoxifying enzyme. The degradation product of this hydrolysis then suppresses induced defence responses by interfering with fundamental signal transduction processes leading to disease resistance.

  17. Optical computing and neural networks; Proceedings of the Meeting, National Chiao Tung Univ., Hsinchu, Taiwan, Dec. 16, 17, 1992

    NASA Technical Reports Server (NTRS)

    Hsu, Ken-Yuh (Editor); Liu, Hua-Kuang (Editor)

    1992-01-01

    The present conference discusses optical neural networks, photorefractive nonlinear optics, optical pattern recognition, digital and analog processors, and holography and its applications. Attention is given to bifurcating optical information processing, neural structures in digital halftoning, an exemplar-based optical neural net classifier for color pattern recognition, volume storage in photorefractive disks, and microlaser-based compact optical neuroprocessors. Also treated are the optical implementation of a feature-enhanced optical interpattern-associative neural network model and its optical implementation, an optical pattern binary dual-rail logic gate module, a theoretical analysis for holographic associative memories, joint transform correlators, image addition and subtraction via the Talbot effect, and optical wavelet-matched filters. (No individual items are abstracted in this volume)

  18. Optical computing and neural networks; Proceedings of the Meeting, National Chiao Tung Univ., Hsinchu, Taiwan, Dec. 16, 17, 1992

    NASA Astrophysics Data System (ADS)

    Hsu, Ken-Yuh; Liu, Hua-Kuang

    The present conference discusses optical neural networks, photorefractive nonlinear optics, optical pattern recognition, digital and analog processors, and holography and its applications. Attention is given to bifurcating optical information processing, neural structures in digital halftoning, an exemplar-based optical neural net classifier for color pattern recognition, volume storage in photorefractive disks, and microlaser-based compact optical neuroprocessors. Also treated are the optical implementation of a feature-enhanced optical interpattern-associative neural network model and its optical implementation, an optical pattern binary dual-rail logic gate module, a theoretical analysis for holographic associative memories, joint transform correlators, image addition and subtraction via the Talbot effect, and optical wavelet-matched filters. (No individual items are abstracted in this volume)

  19. Second NASA Advanced Composites Technology Conference

    NASA Technical Reports Server (NTRS)

    Davis, John G., Jr. (Compiler); Bohon, Herman L. (Compiler)

    1992-01-01

    The conference papers are presented. The Advanced Composite Technology (ACT) Program is a major multi-year research initiative to achieve a national goal of technology readiness before the end of the decade. Conference papers recorded results of research in the ACT Program in the specific areas of automated fiber placement, resin transfer molding, textile preforms, and stitching as these processes influence design, performance, and cost of composites in aircraft structures. These papers will also be included in the Ninth Conference Proceedings to be published by the Federal Aviation Administration as a separate document.

  20. PREFACE: Edison 16

    NASA Astrophysics Data System (ADS)

    Varani, Luca; Palermo, Christophe; Bastard, Gérald

    2009-11-01

    Conference logo On behalf of the organizing committee we welcome all participants to the 16th International Conference on Electron Dynamics In Semiconductors, Optoelectronics and Nanostructures (EDISON). Since the first meeting, organized in 1973 in Modena (Italy), this international conference has been regularly organized mostly each two years, and after 28 years EDISON is back to Montpellier for its 16th edition. This conference was previously known as 'Hot Carriers In Semiconductors' (HCIS). For some years the name was changed into 'Nonequilibrium Carrier Dynamics in Semiconductors' (keeping the acronym HCIS). Then, during the last meeting of the international advisory committee in Tokyo, the decision was taken to find a new denomination that should be more adapted to the latest evolutions in the domains covered by the conference. After several discussions and a vote within the committee, the new acronym of EDISON was chosen. Therefore EDISON 16 can be considered as the last of a long series of conferences and, at the same time, the first of a new cycle of conferences. The primary focus of EDISON is to provide an international meeting place to discuss the latest progress in the field of nonequilibrium classical and quantum carrier dynamics, from semiconductor bulk materials up to advanced structures and nanometric devices. This includes: classical incoherent transport, as well as coherent transport, usually analyzed by means of ultrafast electrical and optical excitations. To accompany the newest developments, TeraHertz phenomena, with a special attention to quantum cascade lasers, have been added to the list of topics. More recently new subjects have been included such as spintronics, transport in organic materials, graphene and carbon nanotubes. This list of topics is regularly modified and updated at each edition of the conference to represent but also anticipate the latest scientific evolutions. The distinctive features of EDISON are: A long-lasting history of 36 years. A fruitful interplay between fundamental and applied science due to a balanced participation of physicists and engineers. Emphasis is put on the physics of future devices rather than on the optimization of existing devices. A balance between theoretical and experimental contributions characterizes the scientific program. The scientific and advisory committees are composed by well-recognized scientists. This year the scientific program was composed by more than 200 contributions divided into 60 oral presentations and 2 poster sessions. To keep a high scientific level, two independent referees have reviewed all submitted abstracts. We are happy to have drawn attendance from more than 30 different countries. We hope that EDISON 16 has been an excellent opportunity for you to meet with colleagues from all over the world in an informal atmosphere, create an opportunity for networking, sharing of scientific and technical information and the building of trust relationships internationally. Luca Varani Christophe Palermo Gérald Bastard EDITORS

  1. International Conference: Milky Way Surveys: The Structure and Evolution of Our Galaxy

    NASA Technical Reports Server (NTRS)

    Clemens, Dan

    2004-01-01

    We were granted NASA support for partial sponsorship of an international conference on Galactic science, held June 15-17, 2003 and hosted by the Institute for Astrophysical Research at Boston University. This conference, entitled 'Milky Way Surveys: The Structure and Evolution of Our Galaxy' drew some 125 scientific experts, researchers, and graduate students to Boston to: (1) Present large area survey plans and findings; (2) Discuss important remaining questions and puzzles in Galactic science; and (3) To inform and excite students and researchers about the potential for using large area survey databases to address key Galactic science questions. An international Scientific Organizing Committee for this conference crafted a tightly packed two-day conference designed to highlight many recent and upcoming large area surveys (including 2MASS, SDSS, MSX, VLA-HI, GRS, and SIRTF/GLIMPSE) and current theoretical understandings and questions. By bringing together experts in the conduct of Galactic surveys and leading theorists, new ways of attacking long-standing scientific questions were encouraged. The titles of most of the talks and posters presented are attached to the end of this report.

  2. NACA Conference on Aircraft Loads, Structures, and Flutter

    NASA Technical Reports Server (NTRS)

    1957-01-01

    This document contains reproductions of technical papers on some of the most recent research results on aircraft loads, flutter, and structures from the NACA laboratories. These papers were presented by members of the staff of the NACA laboratories at the Conference held at the Langley Aeronautical Laboratory March 5, 6, and 7, 1957. The primary purpose of this Conference was to convey to contractors of the military services and others concerned with the design of aircraft these recent research results and to provide those attending an opportunity to discuss the results. The papers in this document are in the same form in which they were presented at the Conference in order to facilitate their prompt distribution. The original presentation and this record are considered as complementary to, rather than as substitutes for, the Committee?s more complete and formal reports. Accordingly, if information from this document is utilized it is requested that this document not be listed as a reference. Individual reports dealing with most of the information presented at the Conference will subsequently be published by NACA and will therefore be suitable as reference material.

  3. Technology 2004, Vol. 2

    NASA Technical Reports Server (NTRS)

    1995-01-01

    Proceedings from symposia of the Technology 2004 Conference, November 8-10, 1994, Washington, DC. Volume 2 features papers on computers and software, virtual reality simulation, environmental technology, video and imaging, medical technology and life sciences, robotics and artificial intelligence, and electronics.

  4. Transformational Leadership, Integrity, and Power

    ERIC Educational Resources Information Center

    Harrison, Laura M.

    2011-01-01

    Transformational leadership enjoys widespread appeal among student affairs professionals. National Association of Student Personnel Administrators (NASPA) and American College Personnel Association (ACPA) conferences frequently feature speakers who promote transformational leadership's two primary tenets: (1) change is the central purpose of…

  5. Considerations and recent advances in neuroscience.

    PubMed

    Gorman, Adrienne M; Doyle, Karen M

    2009-02-01

    Neuroscience is a rapidly developing area of science which has benefitted from the blurring of interdisciplinary boundaries. This was apparent in the range of papers presented at this year's Neuroscience Ireland Conference, held in Galway during August 2008. The event was attended by academics, postdoctoral and postgraduate researchers, scientists from industry and clinicians. The themes of this year's conference, neurodegeneration, neuroregeneration, pain, glial cell biology and psychopharmacology, were chosen for their reflection of areas of strength in neuroscience within Ireland. In addition to basic science, translational research also featured strongly.

  6. High-frequency shear Alfven instability driven by circulating energetic ions in NSTX

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kolesnichenko, Ya. I.; White, R. B.; Yakovenko, Yu. V.

    2006-12-15

    It is shown that a number of features of an instability with the frequency comparable to the ion gyrofrequency observed in the National Spherical Torus Experiment [E. D. Fredrickson et al., 'Observation of hole-clump pair generation by global or compressional Alfven eigenmodes', Contributed Papers, 33rd European Physical Society Conference on Plasma Physics, Rome, 2006, Europhysics Conference Abstracts (European Physical Society, Petit-Lancy, 2006), Report P5.058 (unpublished)] is consistent with the features of the Alfven instability with large, about the inverse, Larmor radius of the energetic ions ({rho}{sub b}{sup -1}) longitudinal wavenumbers. The conclusions drawn are based on an analysis of themore » resonant interaction of the energetic circulating ions and the waves, as well as on the calculation of the instability growth rate taking into account effects of the finite Larmor radius, {rho}{sub b}.« less

  7. PREFACE: Nuclear Cluster Conference; Cluster'07

    NASA Astrophysics Data System (ADS)

    Freer, Martin

    2008-05-01

    The Cluster Conference is a long-running conference series dating back to the 1960's, the first being initiated by Wildermuth in Bochum, Germany, in 1969. The most recent meeting was held in Nara, Japan, in 2003, and in 2007 the 9th Cluster Conference was held in Stratford-upon-Avon, UK. As the name suggests the town of Stratford lies upon the River Avon, and shortly before the conference, due to unprecedented rainfall in the area (approximately 10 cm within half a day), lay in the River Avon! Stratford is the birthplace of the `Bard of Avon' William Shakespeare, and this formed an intriguing conference backdrop. The meeting was attended by some 90 delegates and the programme contained 65 70 oral presentations, and was opened by a historical perspective presented by Professor Brink (Oxford) and closed by Professor Horiuchi (RCNP) with an overview of the conference and future perspectives. In between, the conference covered aspects of clustering in exotic nuclei (both neutron and proton-rich), molecular structures in which valence neutrons are exchanged between cluster cores, condensates in nuclei, neutron-clusters, superheavy nuclei, clusters in nuclear astrophysical processes and exotic cluster decays such as 2p and ternary cluster decay. The field of nuclear clustering has become strongly influenced by the physics of radioactive beam facilities (reflected in the programme), and by the excitement that clustering may have an important impact on the structure of nuclei at the neutron drip-line. It was clear that since Nara the field had progressed substantially and that new themes had emerged and others had crystallized. Two particular topics resonated strongly condensates and nuclear molecules. These topics are thus likely to be central in the next cluster conference which will be held in 2011 in the Hungarian city of Debrechen. Martin Freer Participants and Cluster'07

  8. SCinet Architecture: Featured at the International Conference for High Performance Computing,Networking, Storage and Analysis 2016

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lyonnais, Marc; Smith, Matt; Mace, Kate P.

    SCinet is the purpose-built network that operates during the International Conference for High Performance Computing,Networking, Storage and Analysis (Super Computing or SC). Created each year for the conference, SCinet brings to life a high-capacity network that supports applications and experiments that are a hallmark of the SC conference. The network links the convention center to research and commercial networks around the world. This resource serves as a platform for exhibitors to demonstrate the advanced computing resources of their home institutions and elsewhere by supporting a wide variety of applications. Volunteers from academia, government and industry work together to design andmore » deliver the SCinet infrastructure. Industry vendors and carriers donate millions of dollars in equipment and services needed to build and support the local and wide area networks. Planning begins more than a year in advance of each SC conference and culminates in a high intensity installation in the days leading up to the conference. The SCinet architecture for SC16 illustrates a dramatic increase in participation from the vendor community, particularly those that focus on network equipment. Software-Defined Networking (SDN) and Data Center Networking (DCN) are present in nearly all aspects of the design.« less

  9. 2012 Gordon Research Conference on Bioinspired Materials - Formal Schedule and Speaker/Poster Program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chilkoti, Ashutosk

    2012-06-29

    The emerging, interdisciplinary field of Bioinspired Materials focuses on developing a fundamental understanding of the synthesis, directed self-assembly and hierarchical organization of natural occurring materials, and uses this understanding to engineer new bioinspired artificial materials for diverse applications. The inaugural 2012 Gordon Conference on Bioinspired Materials seeks to capture the excitement of this burgeoning field by a cutting-edge scientific program and roster of distinguished invited speakers and discussion leaders who will address the key issues in the field. The Conference will feature a wide range of topics, such as materials and devices from DNA, reprogramming the genetic code for designmore » of new materials, peptide, protein and carbohydrate based materials, biomimetic systems, complexity in self-assembly, and biomedical applications of bioinspired materials.« less

  10. PREFACE: International Scientific Conference of Young Scientists: Advanced Materials in Construction and Engineering (TSUAB2014)

    NASA Astrophysics Data System (ADS)

    Kopanitsa, Natalia O.

    2015-01-01

    In October 15-17, 2014 International Scientific Conference of Young Scientists: Advanced Materials in Construction and Engineering (TSUAB2014) took place at Tomsk State University of Architecture and Building (Tomsk, Russia). The Conference became a discussion platform for researchers in the fields of studying structure and properties of advanced building materials and included open lectures of leading scientists and oral presentations of master, postgraduate and doctoral students. A special session was devoted to reports of school children who further plan on starting a research career. The Conference included an industrial exhibition where companies displayed the products and services they supply. The companies also gave presentations of their products within the Conference sessions.

  11. Conservation and divergence of C-terminal domain structure in the retinoblastoma protein family

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liban, Tyler J.; Medina, Edgar M.; Tripathi, Sarvind

    The retinoblastoma protein (Rb) and the homologous pocket proteins p107 and p130 negatively regulate cell proliferation by binding and inhibiting members of the E2F transcription factor family. The structural features that distinguish Rb from other pocket proteins have been unclear but are critical for understanding their functional diversity and determining why Rb has unique tumor suppressor activities. We describe here important differences in how the Rb and p107 C-terminal domains (CTDs) associate with the coiled-coil and marked-box domains (CMs) of E2Fs. We find that although CTD–CM binding is conserved across protein families, Rb and p107 CTDs show clear preferences formore » different E2Fs. A crystal structure of the p107 CTD bound to E2F5 and its dimer partner DP1 reveals the molecular basis for pocket protein–E2F binding specificity and how cyclin-dependent kinases differentially regulate pocket proteins through CTD phosphorylation. Our structural and biochemical data together with phylogenetic analyses of Rb and E2F proteins support the conclusion that Rb evolved specific structural motifs that confer its unique capacity to bind with high affinity those E2Fs that are the most potent activators of the cell cycle.« less

  12. Subwavelength resolution from multilayered structure (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Cheng, Bo Han; Jen, Yi-Jun; Liu, Wei-Chih; Lin, Shan-wen; Lan, Yung-Chiang; Tsai, Din Ping

    2016-10-01

    Breaking optical diffraction limit is one of the most important issues needed to be overcome for the demand of high-density optoelectronic components. Here, a multilayered structure which consists of alternating semiconductor and dielectric layers for breaking optical diffraction limitation at THz frequency region are proposed and analyzed. We numerically demonstrate that such multilayered structure not only can act as a hyperbolic metamaterial but also a birefringence material via the control of the external temperature (or magnetic field). A practical approach is provided to control all the diffraction signals toward a specific direction by using transfer matrix method and effective medium theory. Numerical calculations and computer simulation (based on finite element method, FEM) are carried out, which agree well with each other. The temperature (or magnetic field) parameter can be tuned to create an effective material with nearly flat isofrequency feature to transfer (project) all the k-space signals excited from the object to be resolved to the image plane. Furthermore, this multilayered structure can resolve subwavelength structures at various incident THz light sources simultaneously. In addition, the resolution power for a fixed operating frequency also can be tuned by only changing the magnitude of external magnetic field. Such a device provides a practical route for multi-functional material, photolithography and real-time super-resolution image.

  13. Wilderness Medicine Newsletter, 1992.

    ERIC Educational Resources Information Center

    Wilderness Medicine Newsletter, 1992

    1992-01-01

    This document consists of the six issues of "Wilderness Medicine Newsletter" published in 1992. This journal, subtitled "For the recognition, treatment, and prevention of wilderness emergencies," includes feature articles, book reviews, product reviews, letters to the editor, notices of upcoming wilderness conferences, and…

  14. Michael Deceglie | NREL

    Science.gov Websites

    postdoctoral researcher focused on photovoltaic performance and reliability. His current research interests illumination nonuniformity, and outdoor performance of advanced photovoltaic technologies. Featured photovoltaic module," Proceedings of the Thirty-ninth IEEE Photovoltaic Specialists Conference (PVSC), pp

  15. Places to Intervene to Make Complex Food Systems More Healthy, Green, Fair, and Affordable

    PubMed Central

    Malhi, Luvdeep; Karanfil, Özge; Merth, Tommy; Acheson, Molly; Palmer, Amanda; Finegood, Diane T.

    2009-01-01

    A Food Systems and Public Health conference was convened in April 2009 to consider research supporting food systems that are healthy, green, fair, and affordable. We used a complex systems framework to examine the contents of background material provided to conference participants. Application of our intervention-level framework (paradigm, goals, system structure, feedback and delays, structural elements) enabled comparison of the conference themes of healthy, green, fair, and affordable. At the level of system structure suggested actions to achieve these goals are fairly compatible, including broad public discussion and implementation of policies and programs that support sustainable food production and distribution. At the level of paradigm and goals, the challenge of making healthy and green food affordable becomes apparent as some actions may be in conflict. Systems thinking can provide insight into the challenges and opportunities to act to make the food supply more healthy, green, fair, and affordable. PMID:23173029

  16. 12th Central Hardwood Forest Conference

    Treesearch

    Jeffrey W. Stringer; David L. Loftis; Michael Lacki; Thomas Barnes; Robert A. Muller

    1999-01-01

    There were 32 oral presentations, 11 abstracts, and 22 poster presentations presented at the 12th Central Hardwood Forest Conference. Presentation topics included wildlife management, nutrient dynamics, stand structure, reforestation/reclamation, timber harvesting, modeling and inventory, silviculture, disturbance effects, and genetics/tree improvement.

  17. The conference

    Treesearch

    Gordon M. Heisler; Lee P. Herrington

    1977-01-01

    This is a report on the Conference on Metropolitan Physical Environment, held in August 1975 at Syracuse, N.Y., where some 160 scientists and planners met to discuss the use of vegetation, space, and structures to improve the amenities for people who live in metropolitan areas.

  18. Rehabilitation-triggered cortical plasticity after stroke: in vivo imaging at multiple scales (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Allegra Mascaro, Anna Letizia; Conti, Emilia; Lai, Stefano; Spalletti, Cristina; Di Giovanna, Antonino Paolo; Alia, Claudia; Panarese, Alessandro; Sacconi, Leonardo; Micera, Silvestro; Caleo, Matteo; Pavone, Francesco S.

    2017-02-01

    Neurorehabilitation protocols based on the use of robotic devices provide a highly repeatable therapy and have recently shown promising clinical results. Little is known about how rehabilitation molds the brain to promote motor recovery of the affected limb. We used a custom-made robotic platform that provides quantitative assessment of forelimb function in a retraction test. Complementary imaging techniques allowed us to access to the multiple facets of robotic rehabilitation-induced cortical plasticity after unilateral photothrombotic stroke in mice Primary Motor Cortex (Caudal Forelimb Area - CFA). First, we analyzed structural features of vasculature and dendritic reshaping in the peri-infarct area with two-photon fluorescence microscopy. Longitudinal analysis of dendritic branches and spines of pyramidal neurons suggests that robotic rehabilitation promotes the stabilization of peri-infarct cortical excitatory circuits, which is not accompanied by consistent vascular reorganization towards pre-stroke conditions. To investigate if this structural stabilization was linked to functional remapping, we performed mesoscale wide-field imaging on GCaMP6 mice while performing the motor task on the robotic platform. We revealed temporal and spatial features of the motor-triggered cortical activation, shining new light on rehabilitation-induced functional remapping of the ipsilesional cortex. Finally, by using an all-optical approach that combines optogenetic activation of the contralesional hemisphere and wide-field functional imaging of peri-infarct area, we dissected the effect of robotic rehabilitation on inter-hemispheric cortico-cortical connectivity.

  19. Not “Pulling up the Ladder”: Women Who Organize Conference Symposia Provide Greater Opportunities for Women to Speak at Conservation Conferences

    PubMed Central

    Sardelis, Stephanie; Drew, Joshua A.

    2016-01-01

    The scientific community faces numerous challenges in achieving gender equality among its participants. One method of highlighting the contributions made by female scientists is through their selection as featured speakers in symposia held at the conferences of professional societies. Because they are specially invited, symposia speakers obtain a prestigious platform from which to display their scientific research, which can elevate the recognition of female scientists. We investigated the number of female symposium speakers in two professional societies (the Society of Conservation Biology (SCB) from 1999 to 2015, and the American Society of Ichthyologists and Herpetologists (ASIH) from 2005 to 2015), in relation to the number of female symposium organizers. Overall, we found that 36.4% of symposia organizers and 31.7% of symposia speakers were women at the Society of Conservation Biology conferences, while 19.1% of organizers and 28% of speakers were women at the American Society of Ichthyologists and Herpetologists conferences. For each additional female organizer at the SCB and ASIH conferences, there was an average increase of 95% and 70% female speakers, respectively. As such, we found a significant positive relationship between the number of women organizing a symposium and the number of women speaking in that symposium. We did not, however, find a significant increase in the number of women speakers or organizers per symposium over time at either conference, suggesting a need for revitalized efforts to diversify our scientific societies. To further those ends, we suggest facilitating gender equality in professional societies by removing barriers to participation, including assisting with travel, making conferences child-friendly, and developing thorough, mandatory Codes of Conduct for all conferences. PMID:27467580

  20. Relevance of extracellular DNA in rhizosphere

    NASA Astrophysics Data System (ADS)

    Pietramellara, Giacomo; Ascher, Judith; Baraniya, Divyashri; Arfaioli, Paola; Ceccherini, Maria Teresa; Hawes, Martha

    2013-04-01

    One of the most promising areas for future development is the manipulation of the rhizosphere to produce sustainable and efficient agriculture production systems. Using Omics approaches, to define the distinctive features of eDNA systems and structures, will facilitate progress in rhizo-enforcement and biocontrol studies. The relevance of these studies results clear when we consider the plethora of ecological functions in which eDNA is involved. This fraction can be actively extruded by living cells or discharged during cellular lysis and may exert a key role in the stability and variability of the soil bacterial genome, resulting also a source of nitrogen and phosphorus for plants due to the root's capacity to directly uptake short DNA fragments. The adhesive properties of the DNA molecule confer to eDNA the capacity to inhibit or kill pathogenic bacteria by cation limitation induction, and to facilitate formation of biofilm and extracellular traps (ETs), that may protect microorganisms inhabiting biofilm and plant roots against pathogens and allelopathic substances. The ETs are actively extruded by root border cells when they are dispersed in the rhizosphere, conferring to plants the capacity to extend an endogenous pathogen defence system outside the organism. Moreover, eDNA could be involved in rhizoremediation in heavy metal polluted soil acting as a bioflotation reagent.

  1. Virtualization of the Y.E.S. Congress 2009 Roundtable Symposia (Invited)

    NASA Astrophysics Data System (ADS)

    Gonzales, L. M.; Gaines, S. M.

    2009-12-01

    The Y.E.S. Congress 2009 was the first international conference organized by the Y.E.S. Network, an association of early-career geoscientists who represent professional societies, geoscience companies, geoscience departments, and interested policy makers from across the world, in collaboration with the International Year of Planet Earth (IYPE). The conference, hosted by the China University of Geosciences in Beijing, focused on scientific and career challenges faced by early-career geoscientists, with a particular emphasis on how the Y.E.S. Network can work collaboratively and internationally towards solving these challenges and furthering the IYPE motto of “Earth Sciences for Society”. A key features of the Y.E.S. Congress was the implementation of “virtualized” roundtable symposia which engaged senior and early-career geoscientists via presentations, panel discussions, and working group sessions in which strategies related to scientific challenges (i.e. climate change in the polar regions, natural hazards, natural resource sustainability) and academic and career pathway challenges (i.e. academic-industry linkages, gender parity in the geosciences, geoscience education sustainability, and international licensure issues) were developed. These strategies were then tasked to the Y.E.S. Network for further development and implementation. The virtualization of the roundtable symposia facilitated active discussion between those participants and speakers who were physically located at the conference facilities in Beijing with a wider international audience of virtual participants and speakers. This talk will address the key features of the roundtable virtualization, the successes and challenges faced during the pre-conference set-up as well as during the roundtable sessions, and potential future applications.

  2. International conference on "Photosynthesis research for sustainability-2013: in honor of Jalal A. Aliyev", held during June 5-9, 2013, Baku, Azerbaijan.

    PubMed

    Allakhverdiev, Suleyman I; Huseynova, Irada M; Govindjee

    2013-12-01

    In this brief report, we provide a pictorial essay on an international conference "Photosynthesis Research for Sustainability-2013 in honor of Jalal A. Aliyev" that was held in Baku, Azerbaijan, during June 5-9, 2013 ( http://photosynthesis2013.cellreg.org/ ). We begin this report with a brief note on Jalal Aliyev, the honored scientist, and on John Walker (1997 Nobel laureate in Chemistry) who was a distinguished guest and lecturer at the Conference. We briefly describe the Conference, and the program. In addition to the excellent scientific program, a special feature of the Conference was the presentation of awards to nine outstanding young investigators; they are recognized in this report. We have also included several photographs to show the pleasant ambience at this conference. (See http://photosynthesis2013.cellreg.org/Photo-Gallery.php ; https://www.dropbox.com/sh/qcr124dajwffwh6/TlcHBvFu4H?m ; and https://www.copy.com/s/UDlxb9fgFXG9/Baku for more photographs taken by the authors as well as by others.) We invite the readers to the next conferences on "Photosynthesis Research for Sustainability-2014: in honor of Vladimir A. Shuvalov" to be held during June 2-7, 2014, in Pushchino, Russia. Detailed information for this will be posted at the Website: http://photosynthesis2014.cellreg.org/ , and for the subsequent conference on "Photosynthesis Research for Sustainability-2015" to be held in May or June 2015, in Baku, Azerbaijan, at http://photosynthesis2015.cellreg.org/ .

  3. Sixth International Conference on Systems Biology (ICSB 2005)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Professor Andrew Murray

    2005-10-22

    This grant supported the Sixth International Conference on Systems Biology (ICSB 2005), held in Boston, Massachusetts from October 19th to 22nd, 2005. The ICSB is the only major, annual, international conference focused exclusively on the important emerging field of systems biology. It draws together scientists with expertise in theoretical, computational and experimental approaches to understanding biological systems at many levels. Previous ICSB meetings have been held in Tokyo (2000), at Caltech (2001), at the Karolinska Institute (2002), at Washington University in St. Louis (2003), and in Heidelberg (2004). These conferences have been increasingly successful at bringing together the growing communitymore » of established and junior researchers with interests in this area. Boston is home to several groups that have shown leadership in the field and was therefore an ideal place to hold this conference . The executive committee for the conference comprised Jim Collins (Biomedical Engineering, Boston University), Marc Kirschner (chair of the new Department of Systems Biology at Harvard Medical School), Eric Lander (director of the Broad Institute of MIT and Harvard), Andrew Murray (director of Harvard’s Bauer Center for Genomics Research) and Peter Sorger (director of MIT’s Computational and Systems Biology Initiative). There are almost as many definitions of systems biology as there are systems biologists. We take a broad view of the field, and we succeeded in one of our major aims in organizing a conference that bridges two types of divide. The first is that between traditional academic disciplines: each of our sessions includes speakers from biology and from one or more physical or quantitative sciences. The second type includes those that separate experimental biologists from their colleagues who work on theory or computation. Here again, each session included representatives from at least two of these three categories; indeed, many of the speakers combined at least two of the categories in their own research activities. We define systems biology as a widening of focus in biology from individual genes or proteins to the complex networks of these molecules that allow cells and organisms to function. In the same way that conscious thought cannot be said to reside in any single neuron in the brain, simpler biological functions such as cell division arise from the interactions among many components in a network or ‘functional module’. For us, systems biology is characterized by the recognition that a higher-order description of biological function, accompanied by quantitative methods of analysis — often borrowed from disciplines such as physics, engineering, computer science or mathematics — can lead to the identification of general principles that underlie the structure, behavior, and evolution of cells and organisms. The heart of the conference were sessions on six topics: intracellular dynamics (featuring measurements on single cells, and their interpretation); biology by design (synthetic biology); intracellular networks (signal transduction and transcriptional regulation); multicellular networks (development and pattern formation); mechanics and scale in cellular behavior (featuring work on cytoskeletal mechanics, and on scaling relationships in biology); and evolution in action (including experimental evolution, of both real and artificial life-forms). Each session had four invited speakers; 23 of the 24 invited speakers attended (see below). We have selected these speakers not only for the interest of their research, but for their skills as communicators, thereby giving us the best chance of bridging the divides mentioned above. We also made a point of including women, younger investigators and people from outside the United States among the speakers. In addition to the invited speakers, we allotted time in the program for at least five contributed talks, which were selected from the poster submissions. Our aim in selecting these contributors showcased work that is “hot off the bench” (or computer) at the time of the conference, and also created additional opportunities for younger investigators to present their work. The main conference was preceded by a day of tutorials, and followed by two days of workshops, on a range of topics in quantitative, computational and systems biology.« less

  4. Revisiting the structure of the anti-neoplastic glucans of Mycobacterium bovis Bacille Calmette-Guerin. Structural analysis of the extracellular and boiling water extract-derived glucans of the vaccine substrains.

    PubMed

    Dinadayala, Premkumar; Lemassu, Anne; Granovski, Pierre; Cérantola, Stéphane; Winter, Nathalie; Daffé, Mamadou

    2004-03-26

    The attenuated strain of Mycobacterium bovis Bacille Calmette-Guérin (BCG), used worldwide to prevent tuberculosis and leprosy, is also clinically used as an immunotherapeutic agent against superficial bladder cancer. An anti-tumor polysaccharide has been isolated from the boiling water extract of the Tice substrain of BCG and tentatively characterized as consisting primarily of repeating units of 6-linked-glucosyl residues. Mycobacterium tuberculosis and other mycobacterial species produce a glycogen-like alpha-glucan composed of repeating units of 4-linked glucosyl residues substituted at some 6 positions by short oligoglucosyl units that also exhibits an anti-tumor activity. Therefore, the impression prevails that mycobacteria synthesize different types of anti-neoplastic glucans or, alternatively, the BCG substrains are singular in producing a unique type of glucan that may confer to them their immunotherapeutic property. The present study addresses this question through the comparative analysis of alpha-glucans purified from the extracellular materials and boiling water extracts of three vaccine substrains. The polysaccharides were purified, and their structural features were established by mono- and two-dimensional NMR spectroscopy and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of the enzymatic and chemical degradation products of the purified compounds. The glucans isolated by the two methods from the three substrains of BCG were shown to exhibit identical structural features shared with the glycogen-like alpha-glucan of M. tuberculosis and other mycobacteria. Incidentally, we observed an occasional release of dextrans from Sephadex columns that may explain the reported occurrence of 6-substituted alpha-glucans in mycobacteria.

  5. 2010 Gordon Research Conference on Correlated Electron Systems: Final Progress Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Basov, Dmitri N.

    The 2010 Gordon Conference on Correlated Electron Systems will present cutting-edge research on emergent properties arising from strong electronic correlations. The Conference will feature a wide range of topics, such as the role of topology in condensed matter systems, quantum Hall interferometry and non-Abelian statistics, quantum criticality, metal-insulator transition, quantum effects in conductivity, Dirac quasiparticles, and superconductivity in cuprates and pnictides. In addition, we are reserving two sessions for new developments in this field that may arise in the coming year. The Conference will bring together a collection of investigators who are at the forefront of their field, and willmore » provide opportunities for junior scientists and graduate students to present their work in poster format and exchange ideas with leaders in the field. We intend to have talks by established leaders in the field and also by young researchers who have made seminal contributions to various aspects of correlated electron physics, The collegial atmosphere of this Conference, with programmed discussion sessions as well as opportunities for informal gatherings in the afternoons and evenings, provides an avenue for scientists from different disciplines to brainstorm and promotes cross-disciplinary collaborations in the various research areas represented.« less

  6. Funding Proposal for EDISON’20 Conference Buffalo, New York, 07/17 - 07/21, 2017

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bird, Jonathan

    EDISON’20 – The 20th International Conference on Electron Dynamics in Semiconductors, Optoe- lectronics and Nanostructures – was held at the Hyatt Regency Hotel, Buffalo, NY from July 17 – 21, 2017. The technical focus of this conference was on the fundamental physics and applications of nonequilibrium classical and quantum carrier dynamics in semiconductors, optoelectronic de- vices, and nanostructures. This five-day, single-session conference featured a program consisting of some 15 invited talks, given by internationally-renowned academics from the U.S., Europe, and Japan. Their keynote presentations covered topics including: terahertz phenomena in semiconductors; quantum transport in novel two-dimensional semiconductors; topological insulators; mesoscopicmore » phenomena in semiconductors, and; semiconductor spintronics. The invited papers were supplemented by some 30 contributed talks, selected from almost 120 abstracts submitted in response to the conference’s call for papers, and by two poster sessions that each consisted of close to 40 different reports. This critical mass in terms of scientific content ensured a highly vibrant conference, in which leaders in the field had the opportunity to interact closely with early-career scientists.« less

  7. White House Conference on Library and Information Services. Hearing before the Subcommittee on Education, Arts and Humanities of the Committee on Labor and Human Resources. United States Senate, One Hundredth Congress, First Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Committee on Labor and Human Resources.

    Held to authorize a White House Conference on Library and Information Services (WHCLIST) in 1989, this hearing focused on library services for literacy, productivity, and democracy as well as on the conference structure and costs. Statements and supporting information provided by the following individuals and institutions were presented: (1)…

  8. Structure and Governance of Library Networks: A Theme Conference Summary. Issues for Consideration. White House Conference on Library and Information Services: Pre-Conference Meetings on Special Themes, November 6-8, 1978.

    ERIC Educational Resources Information Center

    Galvin, Thomas J.

    This paper constitutes a summary of the major topics discussed by the nearly 500 librarians, information specialists, representatives of the information industry, and other interested individuals who participated in a national forum for the identification, elucidation, and discussion of issues relating to library networks, as a contribution to the…

  9. 6th international conference on case histories in geotechnical engineering August 2008conference report.

    DOT National Transportation Integrated Search

    2009-01-01

    Due to uncertainty in the nature of soils, a systematic study of the performance of geotechnical structures and its match with predictions is extremely important. Therefore, considerable research effort is being devoted to geotechnical engineering th...

  10. The Hsp90 mosaic: a picture emerges

    PubMed Central

    Mayer, Matthias P; Prodromou, Chrisostomos; Frydman, Judith

    2012-01-01

    Hsp90s, molecular chaperones critically involved in many essential cellular processes, were the focus of a recent international conference held in Seeon, Germany. The scope of the conference ranged from structural and mechanistic insights all the way to medical applications. PMID:19125165

  11. Proceedings of the 7th central hardwood conference; 1989 March 5-8; Carbondale, IL.

    Treesearch

    George Rink; Carl A. Budelsky

    1989-01-01

    Proceedings of the seventh central hardwood forest conference, March 5-8, 1989 at Carbondale, Illinois. Includes 48 manuscripts dealing with silviculture, biology, management, protection, regeneration, utilization, structure, hydrology, and research policy in the central hardwood forest.

  12. PREFACE: 8th International Conference on Advanced Infocomm Technology (ICAIT 2015)

    NASA Astrophysics Data System (ADS)

    Qiu, M.; Zhao, W.; Shum, P. Ping

    2016-02-01

    The 2015 IEEE 8th International Conference on Advanced Infocomm Technology (ICAIT 2015) was held in Hangzhou, China, during 25-27, October 2015, following the successes of previous events held in Shenzhan, Xi'an, Haikou, Wuhan, Paris, Hsinchu, and Fuzhou. This year the ICAIT 2015 aimed to bring together researchers, developers, and users in both industry and academia in the world for sharing state-of-art results, for exploring new areas of research and development, and to discuss emerging issues on advanced infocomm technology. The conference was hosted by Zhejiang University and China Satellite Maritime Tracking and Control Department. It was organized by the State Ley Laboratory of Modern Optical Instrumentation of Zhejiang University, in collaboration with the Joint International Research Laboratory of Photonics of Zhejiang University. More than 150 international participants from 9 foreign countries attended the conference. The ICAIT 2015 was featured with 4 plenary lectures (by Xiaoyi Bao, Benjamin J. Eggleton, Min Gu, and Chinlon Lin, respectively), and 40 invited talks, in which a wide range of topics were covered and the most recent significant results were presented. Including oral and poster presentations, 138 abstracts were presented in the conference, some of which were selected to publish in full papers in this edition of Journal of Physics: Conference Series. With the excellent quality of the presentations, the ICAIT 2015 was a success. We also wish to thank the sponsors of the conference, and particularly the technical program committee and the local organizing committee.

  13. 3rd International Conference on Structural Nano Composites (NANOSTRUC2016)

    NASA Astrophysics Data System (ADS)

    Njuguna, J.

    2017-05-01

    The Robert Gordon University, Aberdeen hosted The NANOSTRUC 2016 in Aberdeen (Scotland, United Kingdom). The conference focused on ‘Nanoscience and Nanotechnologies - Recent Advances towards Nanoproducts and Applications’. It promoted activities in various areas on materials and structures by providing a forum for exchange of ideas, presentation of technical achievements and discussion of future directions. The conference benefitted from keynote lectures focused on topical issues in nanosciences and nanotechnology. The key sessions were on Application of Nanomaterials and Nanocomposites, Functional Nanocomposites, Graphene and Carbon-based Nanocomposites, Metallic and Metals Oxide Nanocomposites, Sustainability - Nanosafety & Environment, Toughness of Polymer Nanocomposites, Biocomposites and Nanofibres and on Fibre Reinforced Composites. A sample of papers presented at the NANOSTRUC 2016 are briefly summarised in this Issue

  14. Wilderness Medicine Newsletter, 1996.

    ERIC Educational Resources Information Center

    Weber, Holly A., Ed.; And Others

    1996-01-01

    This document consists of the six issues of the "Wilderness Medicine Newsletter" published during 1996. The newsletter addresses the treatment and prevention of medical emergencies in the wilderness and training resources. Issues typically include feature articles, interviews with doctors in the wilderness, conferences and training…

  15. Florida Journal of Communication Disorders, 1996.

    ERIC Educational Resources Information Center

    Langhans, Joseph J., Ed.

    1996-01-01

    This annual volume is a compilation of professional articles and proceedings from a conference addressing timely issues in speech-language pathology and audiology. Featured articles include: (1) "Glottal Airflow: Instrumentation and Interpretation" (Christine M. Sapienza); (2) "Clinical Implications of Motor Speech Disorders in…

  16. Classroom Ready Teaching Moments

    ERIC Educational Resources Information Center

    Whalen, D. Joel; Coker, Kesha K.

    2017-01-01

    This article features thumbnail descriptions of 26 "Teaching Moments" presented at the Society for Marketing Advances 2016 Annual Conference. A wide variety of marketing education interventions are presented, from games that teach marketing fundamentals and enhance faculty effectiveness when counseling students, to visualizing data, and…

  17. Websites of Note

    ERIC Educational Resources Information Center

    Parslow, Graham R.

    2011-01-01

    This article features websites related to biochemistry and molecular biology education. They include: (1) Scitable (www.nature.com/scitable); (2) Educause (www.educause.edu); (3) The Journal of Computer Assisted Learning (onlinelibrary.wiley.com/journal/10.1111/(ISSN)1365-2729); (4) European Conference on eLearning…

  18. Structural Reform in Higher Education Collective Bargaining. Proceedings of the Annual Conference of the National Center for the Study of Collective Bargaining in Higher Education and the Professions (12th, New York, New York, April 1984).

    ERIC Educational Resources Information Center

    Douglas, Joel M., Ed.

    Structural reform in higher education collective bargaining is examined in these conference proceedings, along with recent state bargaining legislation, and legal, union, and management views concerning sex discrimination in higher education. The 19 article topics and authors include: the problem of reshaping the fringe package (Claude Campbell);…

  19. Structure-based methods to predict mutational resistance to diarylpyrimidine non-nucleoside reverse transcriptase inhibitors.

    PubMed

    Azeem, Syeda Maryam; Muwonge, Alecia N; Thakkar, Nehaben; Lam, Kristina W; Frey, Kathleen M

    2018-01-01

    Resistance to non-nucleoside reverse transcriptase inhibitors (NNRTIs) is a leading cause of HIV treatment failure. Often included in antiviral therapy, NNRTIs are chemically diverse compounds that bind an allosteric pocket of enzyme target reverse transcriptase (RT). Several new NNRTIs incorporate flexibility in order to compensate for lost interactions with amino acid conferring mutations in RT. Unfortunately, even successful inhibitors such as diarylpyrimidine (DAPY) inhibitor rilpivirine are affected by mutations in RT that confer resistance. In order to aid drug design efforts, it would be efficient and cost effective to pre-evaluate NNRTI compounds in development using a structure-based computational approach. As proof of concept, we applied a residue scan and molecular dynamics strategy using RT crystal structures to predict mutations that confer resistance to DAPYs rilpivirine, etravirine, and investigational microbicide dapivirine. Our predictive values, changes in affinity and stability, are correlative with fold-resistance data for several RT mutants. Consistent with previous studies, mutation K101P is predicted to confer high-level resistance to DAPYs. These findings were further validated using structural analysis, molecular dynamics, and an enzymatic reverse transcription assay. Our results confirm that changes in affinity and stability for mutant complexes are predictive parameters of resistance as validated by experimental and clinical data. In future work, we believe that this computational approach may be useful to predict resistance mutations for inhibitors in development. Published by Elsevier Inc.

  20. Coordinating the Structural Rearrangements Associated with Unidirectional Proton Transfer in the Bacteriorhodopsin Photocycle Induced by Deprotonation of the Proton-Release Group: A Time-Resolved Difference FTIR Spectroscopic Study†

    PubMed Central

    Morgan, Joel E.; Vakkasoglu, Ahmet S.; Lanyi, Janos K.; Gennis, Robert B.; Maeda, Akio

    2014-01-01

    In the photocycle of bacteriorhodopsin at pH 7, proton release from the proton releasing group (PRG) to the extracellular medium occurs during formation of the M intermediate. This proton release is inhibited at acidic pH, below the pKa of the PRG, ∼6 in M, and instead occurs later in the cycle as the initial state is restored from the O intermediate. Here, structural changes related to deprotonation of the PRG have been investigated by time-resolved FTIR spectroscopy at 25°C. The vibrational features at 2100-1790 cm-1, 1730-1685 cm-1, 1661 cm-1, and 1130-1045 cm-1 have greater negative intensity in the pure M-minus-BR spectrum and even in the M-minus-BR spectrum, that is present earlier together with the L-minus-BR spectrum, at pH 7, than in the corresponding M-minus-BR spectra at pH 5 or pH 4. The D212N mutation abolishes the decreases in the intensities of the broad feature between 1730 and 1685 cm-1 and the band at 1661 cm-1. The 1730-1685 cm-1 feature may arise from transition dipole coupling of the backbone carbonyl groups of Glu204, Phe208, Asp212 and Lys216 interacting with Tyr57 and C15-H of the chromophore. The 1661 cm-1 band, which is insensitive to D2O substitution, may arise by interaction of the backbone carbonyl of Asp212 with C15-H. The 2100-1790 cm-1 feature with a trough at 1885 cm-1 could be due to a water cluster. Depletion of these bands upon deprotonation of the PRG is attributable to disruption of a coordinated structure, held in place by interactions of Asp212. Deprotonation of the PRG is accompanied also by disruption of the interaction of the water molecule near Arg82. The liberated Asp212 may stabilize the protonated state of Asp85, and thus confer uni-directionality to the transport. PMID:20232848

  1. Structural Integrity and Durability of Reusable Space Propulsion Systems

    NASA Technical Reports Server (NTRS)

    1991-01-01

    A two-day conference on the structural integrity and durability of reusable space propulsion systems was held on 14 to 15 May 1991 at the NASA Lewis Research Center. Presentations were made by industry, university, and government researchers organized into four sessions: (1) aerothermodynamic loads; (2) instrumentation; (3) fatigue, fracture, and constitutive modeling; and (4) structural dynamics. The principle objectives were to disseminate research results and future plans in each of four areas. This publication contains extended abstracts and the visual material presented during the conference. Particular emphasis is placed on the Space Shuttle Main Engine (SSME) and the SSME turbopump.

  2. ICCK Conference Final Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Green, William H.

    2013-05-28

    The 7th International Conference on Chemical Kinetics (ICCK) was held July 10-14, 2011, at Massachusetts Institute of Technology (MIT), in Cambridge, MA, hosted by Prof. William H. Green of MIT's Chemical Engineering department. This cross-disciplinary meeting highlighted the importance of fundamental understanding of elementary reactions to the full range of chemical investigations. The specific conference focus was on elementary-step kinetics in both the gas phase and in condensed phase. The meeting provided a unique opportunity to discuss how the same reactive species and reaction motifs manifest under very different reaction conditions (e.g. atmospheric, aqueous, combustion, plasma, in nonaqueous solvents, onmore » surfaces.). The conference featured special sessions on new/improved experimental techniques, improved models and data analysis for interpreting complicated kinetics, computational kinetics (especially rate estimates for large kinetic models), and a panel discussion on how the community should document/archive kinetic data. In the past, this conference had been limited to homogeneous gas-phase and liquid-phase systems. This conference included studies of heterogeneous kinetics which provide rate constants for, or insight into, elementary reaction steps. This Grant from DOE BES covered about half of the subsidies we provided to students and postdocs who attended the conference, by charging them reduced-rate registration fees. The complete list of subsidies provided are listed in Table 1 below. This DOE funding was essential to making the conference affordable to graduate students, and indeed the attendance at this conference was higher than at previous conferences in this series. Donations made by companies provided additional subsidies, leveraging the DOE funding. The conference was very effective in educating graduate students and important in fostering scientific interactions, particularly between scientists studying gas phase and liquid phase kinetics, since those two communities do not meet very often (it had been 6 years since the last time this conference had been held). The conference at MIT was so successful that European scientists decided to organize a similar conference (it will be held in Seville, Spain in July 2013). Almost 200 scientists participated, with more than 100 oral presentations and many poster presentations. A complete list of the presentations and their abstracts are given in the attachment. The conference led to many peer-reviewed papers published in several Special Issues of the International Journal of Chemical Kinetics in early 2012.« less

  3. The crystal structure of the Leishmania infantum Silent Information Regulator 2 related protein 1: Implications to protein function and drug design.

    PubMed

    Ronin, Céline; Costa, David Mendes; Tavares, Joana; Faria, Joana; Ciesielski, Fabrice; Ciapetti, Paola; Smith, Terry K; MacDougall, Jane; Cordeiro-da-Silva, Anabela; Pemberton, Iain K

    2018-01-01

    The de novo crystal structure of the Leishmania infantum Silent Information Regulator 2 related protein 1 (LiSir2rp1) has been solved at 1.99Å in complex with an acetyl-lysine peptide substrate. The structure is broadly commensurate with Hst2/SIRT2 proteins of yeast and human origin, reproducing many of the structural features common to these sirtuin deacetylases, including the characteristic small zinc-binding domain, and the larger Rossmann-fold domain involved in NAD+-binding interactions. The two domains are linked via a cofactor binding loop ordered in open conformation. The peptide substrate binds to the LiSir2rp1 protein via a cleft formed between the small and large domains, with the acetyl-lysine side chain inserting further into the resultant hydrophobic tunnel. Crystals were obtained only with recombinant LiSir2rp1 possessing an extensive internal deletion of a proteolytically-sensitive region unique to the sirtuins of kinetoplastid origin. Deletion of 51 internal amino acids (P253-E303) from LiSir2rp1 did not appear to alter peptide substrate interactions in deacetylation assays, but was indispensable to obtain crystals. Removal of this potentially flexible region, that otherwise extends from the classical structural elements of the Rossmann-fold, specifically the β8-β9 connector, appears to result in lower accumulation of the protein when expressed from episomal vectors in L. infantum SIR2rp1 single knockout promastigotes. The biological function of the large serine-rich insertion in kinetoplastid/trypanosomatid sirtuins, highlighted as a disordered region with strong potential for post-translational modification, remains unknown but may confer additional cellular functions that are distinct from their human counterparts. These unique molecular features, along with the resolution of the first kinetoplastid sirtuin deacetylase structure, present novel opportunities for drug design against a protein target previously established as essential to parasite survival and proliferation.

  4. Actes des Journees de linguistique (Proceedings of the Linguistics Conference) (6th, 1992).

    ERIC Educational Resources Information Center

    Brousseau, Martin, Ed.; And Others

    Papers, all in French, presented at a conference on linguistics include: "Machine Translation: Historic Aspects" (Ghada Attieh); "Translation and Conditioning" (Stephanie Bedard); "Semantic or Pre-Semantic Structures? From Perception to Causation" (Denise Belanger); "Presentation of Poetry Sung in Maroc"…

  5. Nuclear Data Sheets page at the NNDC

    Science.gov Websites

    for ENDF. 2014 - ND2013 Conference Proceedings. Topics include the opening and plenary talks, ENDF-6 Conference Proceedings. Topics include neutron induced reactions, gamma and charged particle induced . Topics include mass evaluations, nuclear structure, antineutrino studies, medical physics, education, and

  6. Can Humans Fly Action Understanding with Multiple Classes of Actors

    DTIC Science & Technology

    2015-06-08

    recognition using structure from motion point clouds. In European Conference on Computer Vision, 2008. [5] R. Caruana. Multitask learning. Machine Learning...tonomous driving ? the kitti vision benchmark suite. In IEEE Conference on Computer Vision and Pattern Recognition, 2012. [12] L. Gorelick, M. Blank

  7. MODSIM World 2007 Conference and Expo: Select Papers and Presentations from the Education and Training Track

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E. (Editor); Sullivan, Shannon (Editor); Sanchez, Alicia (Editor)

    2008-01-01

    This NASA Conference Publication features select papers and PowerPoint presentations from the Education and Training Track of MODSIM World 2007 Conference and Expo. Invited speakers and panelists of national and international renown, representing academia, industry and government, discussed how modeling and simulation (M&S) technology can be used to accelerate learning in the K-16 classroom, especially when using M&S technology as a tool for integrating science, technology, engineering and mathematics (STEM) classes. The presenters also addressed the application ofM&S technology to learning and training outside of the classroom. Specific sub-topics of the presentations included: learning theory; curriculum development; professional development; tools/user applications; implementation/infrastructure/issues; and workforce development. There was a session devoted to student M&S competitions in Virginia too, as well as a poster session.

  8. Conference report from the International Congress on Infectious Diseases 2014: Part One. 16th International Congress on Infectious Diseases, Cape Town, South Africa 2-5 April 2014.

    PubMed

    McLoughlin, Hilda

    2014-01-01

    The 16th International Congress on Infectious Diseases (ICID) was held in Cape Town this year, marking the return of the conference to Africa for the first time in 22 years. While infectious diseases such as malaria, tuberculosis and HIV--all still prevalent in the African healthcare landscape--dominated the program, the conference featured several important sessions on fungal infection and a significant number of posters devoted to this critical medical area. Within the context of the rise of antimicrobial resistance, now identified by the WHO as one of the three greatest threats to human health, came the message that resistance is not limited to antimicrobials, but that antifungal resistance is also a significant and emerging threat worldwide.

  9. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Granier, Sébastien; Manglik, Aashish; Kruse, Andrew C.

    The opioid receptor family comprises three members, the {mu}-, {delta}- and {kappa}-opioid receptors, which respond to classical opioid alkaloids such as morphine and heroin as well as to endogenous peptide ligands like endorphins. They belong to the G-protein-coupled receptor (GPCR) superfamily, and are excellent therapeutic targets for pain control. The {delta}-opioid receptor ({delta}-OR) has a role in analgesia, as well as in other neurological functions that remain poorly understood. The structures of the {mu}-OR and {kappa}-OR have recently been solved. Here we report the crystal structure of the mouse {delta}-OR, bound to the subtype-selective antagonist naltrindole. Together with the structuresmore » of the {mu}-OR and {kappa}-OR, the {delta}-OR structure provides insights into conserved elements of opioid ligand recognition while also revealing structural features associated with ligand-subtype selectivity. The binding pocket of opioid receptors can be divided into two distinct regions. Whereas the lower part of this pocket is highly conserved among opioid receptors, the upper part contains divergent residues that confer subtype selectivity. This provides a structural explanation and validation for the 'message-address' model of opioid receptor pharmacology, in which distinct 'message' (efficacy) and 'address' (selectivity) determinants are contained within a single ligand. Comparison of the address region of the {delta}-OR with other GPCRs reveals that this structural organization may be a more general phenomenon, extending to other GPCR families as well.« less

  10. Advances in systems biology: computational algorithms and applications.

    PubMed

    Huang, Yufei; Zhao, Zhongming; Xu, Hua; Shyr, Yu; Zhang, Bing

    2012-01-01

    The 2012 International Conference on Intelligent Biology and Medicine (ICIBM 2012) was held on April 22-24, 2012 in Nashville, Tennessee, USA. The conference featured six technical sessions, one tutorial session, one workshop, and 3 keynote presentations that covered state-of-the-art research activities in genomics, systems biology, and intelligent computing. In addition to a major emphasis on the next generation sequencing (NGS)-driven informatics, ICIBM 2012 aligned significant interests in systems biology and its applications in medicine. We highlight in this editorial the selected papers from the meeting that address the developments of novel algorithms and applications in systems biology.

  11. FleXConf: A Flexible Conference Assistant Using Context-Aware Notification Services

    NASA Astrophysics Data System (ADS)

    Armenatzoglou, Nikos; Marketakis, Yannis; Kriara, Lito; Apostolopoulos, Elias; Papavasiliou, Vicky; Kampas, Dimitris; Kapravelos, Alexandros; Kartsonakis, Eythimis; Linardakis, Giorgos; Nikitaki, Sofia; Bikakis, Antonis; Antoniou, Grigoris

    Integrating context-aware notification services to ubiquitous computing systems aims at the provision of the right information to the right users, at the right time, in the right place, and on the right device, and constitutes a significant step towards the realization of the Ambient Intelligence vision. In this paper, we present FlexConf, a semantics-based system that supports location-based, personalized notification services for the assistance of conference attendees. Its special features include an ontology-based representation model, rule-based context-aware reasoning, and a novel positioning system for indoor environments.

  12. Three featured plenary sessions

    NASA Astrophysics Data System (ADS)

    2012-07-01

    The conference included three plenary sessions. The plenary on Governance, Security, Economy, and the Ecosystem of the Changing Arctic featured Vera Alexander, president, Arctic Research Consortium of the U.S.; Alan Thornhill, chief environmental officer, U.S. Department of the Interior's Bureau of Ocean Energy Management; and Fran Ulmer, chair, U.S. Arctic Research Commission. A plenary on the U.N. Convention on the Law of the Sea featured Ambassador David Balton, deputy assistant secretary for oceans and fisheries, U.S. Department of State; and Rear Admiral Frederick Kenney Jr., judge advocate general and chief counsel, U.S. Coast Guard. The plenary on Science and the 21st Century featured Phil Keslin, chief technology officer, small lab within Google.

  13. HBCUs Research Conference Agenda and Abstracts

    NASA Technical Reports Server (NTRS)

    Dutta, Sunil (Compiler)

    1997-01-01

    The purpose of this Historically Black Colleges and Universities (HBCUS) Research Conference was to provide an opportunity for principal investigators and their students to present research progress reports. The abstracts included in this report indicate the range and quality of research topics such as aeropropulsion, space propulsion, space power, fluid dynamics, designs, structures and materials being funded through grants from Lewis Research Center to HBCUS. The conference generated extensive networking between students, principal investigators, Lewis technical monitors, and other Lewis researchers.

  14. HBCUs Research Conference Agenda and Abstracts

    NASA Technical Reports Server (NTRS)

    Dutta, Sunil (Compiler)

    1998-01-01

    The purpose of this Historically Black Colleges and Universities (HBCUs) Research Conference was to provide an opportunity for principal investigators and their students to present research progress reports. The abstracts included in this report indicate the range and quality of research topics such as aeropropulsion, space propulsion, space power, fluid dynamics, designs, structures and materials being funded through grants from Lewis Research Center to HBCUs. The conference generated extensive networking between students, principal investigators, Lewis technical monitors, and other Lewis researchers.

  15. HBCUs Research Conference agenda and abstracts

    NASA Technical Reports Server (NTRS)

    Dutta, Sunil (Compiler)

    1995-01-01

    The purpose of this Historically Black Colleges and Universities (HBCUs) Research conference was to provide an opportunity for principal investigators and their students to present research progress reports. The abstracts included in this report indicate the range and quality of research topics such as aeropropulsion, space propulsion, space power, fluid dynamics, designs, structures and materials being funded through grants from Lewis Research Center to HBCUs. The conference generated extensive networking between students, principal investigators, Lewis technical monitors, and other Lewis researchers.

  16. Children and Family Structures: Child and Different Relationships of Recent Family Types. Proceedings from the Fenno Hungarian Conference on Recent Family Types (Lahti, Finland, July 5-7, 1989).

    ERIC Educational Resources Information Center

    Kalliopuska, Mirja, Ed.

    This publication reports the proceedings of the Fenno-Hungarian Conference on Recent Family Types, which was held in Lahti, Finland, in July, 1989. The purpose of the conference was to discuss the effect of changing social conditions on the family, family types, and home education in Hungary and Finland. A series of papers was presented. Topics…

  17. A protein coevolution method uncovers critical features of the Hepatitis C Virus fusion mechanism

    PubMed Central

    Douam, Florian; Mancip, Jimmy; Mailly, Laurent; Montserret, Roland; Ding, Qiang; Verhoeyen, Els; Baumert, Thomas F.; Ploss, Alexander; Carbone, Alessandra

    2018-01-01

    Amino-acid coevolution can be referred to mutational compensatory patterns preserving the function of a protein. Viral envelope glycoproteins, which mediate entry of enveloped viruses into their host cells, are shaped by coevolution signals that confer to viruses the plasticity to evade neutralizing antibodies without altering viral entry mechanisms. The functions and structures of the two envelope glycoproteins of the Hepatitis C Virus (HCV), E1 and E2, are poorly described. Especially, how these two proteins mediate the HCV fusion process between the viral and the cell membrane remains elusive. Here, as a proof of concept, we aimed to take advantage of an original coevolution method recently developed to shed light on the HCV fusion mechanism. When first applied to the well-characterized Dengue Virus (DENV) envelope glycoproteins, coevolution analysis was able to predict important structural features and rearrangements of these viral protein complexes. When applied to HCV E1E2, computational coevolution analysis predicted that E1 and E2 refold interdependently during fusion through rearrangements of the E2 Back Layer (BL). Consistently, a soluble BL-derived polypeptide inhibited HCV infection of hepatoma cell lines, primary human hepatocytes and humanized liver mice. We showed that this polypeptide specifically inhibited HCV fusogenic rearrangements, hence supporting the critical role of this domain during HCV fusion. By combining coevolution analysis and in vitro assays, we also uncovered functionally-significant coevolving signals between E1 and E2 BL/Stem regions that govern HCV fusion, demonstrating the accuracy of our coevolution predictions. Altogether, our work shed light on important structural features of the HCV fusion mechanism and contributes to advance our functional understanding of this process. This study also provides an important proof of concept that coevolution can be employed to explore viral protein mediated-processes, and can guide the development of innovative translational strategies against challenging human-tropic viruses. PMID:29505618

  18. Mobile robots IV; Proceedings of the Meeting, Philadelphia, PA, Nov. 6, 7, 1989

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wolfe, W.J.; Chun, W.H.

    1990-01-01

    The present conference on mobile robot systems discusses high-speed machine perception based on passive sensing, wide-angle optical ranging, three-dimensional path planning for flying/crawling robots, navigation of autonomous mobile intelligence in an unstructured natural environment, mechanical models for the locomotion of a four-articulated-track robot, a rule-based command language for a semiautonomous Mars rover, and a computer model of the structured light vision system for a Mars rover. Also discussed are optical flow and three-dimensional information for navigation, feature-based reasoning trail detection, a symbolic neural-net production system for obstacle avoidance and navigation, intelligent path planning for robot navigation in an unknown environment,more » behaviors from a hierarchical control system, stereoscopic TV systems, the REACT language for autonomous robots, and a man-amplifying exoskeleton.« less

  19. Extracellular matrix structure governs invasion resistance in bacterial biofilms.

    PubMed

    Nadell, Carey D; Drescher, Knut; Wingreen, Ned S; Bassler, Bonnie L

    2015-08-01

    Many bacteria are highly adapted for life in communities, or biofilms. A defining feature of biofilms is the production of extracellular matrix that binds cells together. The biofilm matrix provides numerous fitness benefits, including protection from environmental stresses and enhanced nutrient availability. Here we investigate defense against biofilm invasion using the model bacterium Vibrio cholerae. We demonstrate that immotile cells, including those identical to the biofilm resident strain, are completely excluded from entry into resident biofilms. Motile cells can colonize and grow on the biofilm exterior, but are readily removed by shear forces. Protection from invasion into the biofilm interior is mediated by the secreted protein RbmA, which binds mother-daughter cell pairs to each other and to polysaccharide components of the matrix. RbmA, and the invasion protection it confers, strongly localize to the cell lineages that produce it.

  20. Informatics application provides instant research to practice benefits.

    PubMed Central

    Bowles, K. H.; Peng, T.; Qian, R.; Naylor, M. D.

    2001-01-01

    A web-based research information system was designed to enable our research team to efficiently measure health related quality of life among frail older adults in a variety of health care settings (home care, nursing homes, assisted living, PACE). The structure, process, and outcome data is collected using laptop computers and downloaded to a SQL database. Unique features of this project are the ability to transfer research to practice by instantly sharing individual and aggregate results with the clinicians caring for these elders and directly impacting the quality of their care. Clinicians can also dial in to the database to access standard queries or receive customized reports about the patients in their facilities. This paper will describe the development and implementation of the information system. The conference presentation will include a demonstration and examples of research to practice benefits. PMID:11825156

  1. Trends in National Emergency Medicine Conference Didactic Lectures Over a 6-Year Period.

    PubMed

    Gottlieb, Michael; Riddell, Jeff; Njie, Abdoulie

    2017-01-01

    National conference didactic lectures have traditionally featured hour-long lecture-based presentations. However, there is evidence that longer lectures can lead to both decreased attention and retention of information. The authors sought to identify trends in lecture duration, lecture types, and number of speakers at four national emergency medicine (EM) conferences over a 6-year period. The authors performed a retrospective analysis of the length, number of speakers, and format of didactic lectures at four different national EM conferences over 6 years. The authors abstracted data from the national academic assemblies for the four largest not-for-profit EM organizations in the United States: American Academy of Emergency Medicine, American College of Emergency Physicians, Council of Emergency Medicine Residency Directors, and Society for Academic Emergency Medicine. There was a significant yearly decrease in the mean lecture lengths for three of the four conferences. There was an increase in the percentage of rapid fire sessions over the preceding 2 years with a corresponding decrease in the percentage of general educational sessions. There was no significant difference in the mean number of speakers per lecture. An analysis of 4210 didactic lecture sessions from the annual meetings of four national EM organizations over a 6-year period showed significant decreases in mean lecture length. These findings can help to guide EM continuing medical education conference planning and research.

  2. The 3rd World Conference on Kisspeptin, "Kisspeptin 2017: Brain and Beyond":Unresolved questions, challenges and future directions for the field.

    PubMed

    Lehman, Michael N; Coolen, Lique M; Steiner, Robert A; Neal-Perry, Genevieve; Wang, Luhong; Moenter, Suzanne M; Moore, Aleisha M; Goodman, Robert L; Hwa-Yeo, Shel; Padilla, Stephanie L; Kauffman, Alexander S; Garcia, James; Kelly, Martin J; Clarkson, Jenny; Radovick, Sally; Babwah, Andy V; Leon, Silvia; Tena-Sempere, Manuel; Comninos, Alex; Seminara, Stephanie; Dhillo, Waljit S; Levine, Jon; Terasawa, Ei; Negron, Ariel; Herbison, Allan E

    2018-04-14

    The 3 rd World Conference on Kisspeptin, "Kisspeptin 2017: Brain and Beyond" was held March 30-31 at the Rosen Centre Hotel in Orlando, Florida, providing an international forum for multidisciplinary scientists to meet and share cutting-edge research on kisspeptin biology and its relevance to human health and disease. The meeting built upon previous world conferences focused on the role of kisspeptin and associated peptides in the control of gonadotropin-releasing hormone (GnRH) secretion and reproduction. Based on recent discoveries, the scope of this meeting was expanded to include functions of kisspeptin and related peptides in other physiological systems including energy homeostasis, pregnancy, ovarian and uterine function, and thermoregulation. In addition, discussions addressed the translation of basic knowledge of kisspeptin biology to the treatment of disease, with the goal of seeking consensus about the best approaches to improve human health. The two-day meeting featured a non-traditional structure, with each day starting with poster sessions followed by lunch discussions and facilitated large-group sessions with short presentations to maximize the exchange of new, unpublished data. Topics were identified by a survey prior to the meeting, and focused on major unresolved questions, important controversies, and future directions in the field. Finally, career development activities provided mentoring for trainees and junior investigators, and networking opportunities for those individuals with established researchers in the field. Overall, the meeting was rated as a success by attendees and covered a wide range of lively and provocative discussion topics on the changing nature of the field of "kisspeptinology" and its future. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  3. Molecular Features Underlying Selectivity in Chicken Bitter Taste Receptors.

    PubMed

    Di Pizio, Antonella; Shy, Nitzan; Behrens, Maik; Meyerhof, Wolfgang; Niv, Masha Y

    2018-01-01

    Chickens sense the bitter taste of structurally different molecules with merely three bitter taste receptors ( Gallus gallus taste 2 receptors, ggTas2rs), representing a minimal case of bitter perception. Some bitter compounds like quinine, diphenidol and chlorpheniramine, activate all three ggTas2rs, while others selectively activate one or two of the receptors. We focus on bitter compounds with different selectivity profiles toward the three receptors, to shed light on the molecular recognition complexity in bitter taste. Using homology modeling and induced-fit docking simulations, we investigated the binding modes of ggTas2r agonists. Interestingly, promiscuous compounds are predicted to establish polar interactions with position 6.51 and hydrophobic interactions with positions 3.32 and 5.42 in all ggTas2rs; whereas certain residues are responsible for receptor selectivity. Lys 3.29 and Asn 3.36 are suggested as ggTas2r1-specificity-conferring residues; Gln 6.55 as ggTas2r2-specificity-conferring residue; Ser 5.38 and Gln 7.42 as ggTas2r7-specificity conferring residues. The selectivity profile of quinine analogs, quinidine, epiquinidine and ethylhydrocupreine, was then characterized by combining calcium-imaging experiments and in silico approaches. ggTas2r models were used to virtually screen BitterDB compounds. ~50% of compounds known to be bitter to human are likely to be bitter to chicken, with 25, 20, 37% predicted to be ggTas2r1, ggTas2r2, ggTas2r7 agonists, respectively. Predicted ggTas2rs agonists can be tested with in vitro and in vivo experiments, contributing to our understanding of bitter taste in chicken and, consequently, to the improvement of chicken feed.

  4. The Brown University Child and Adolescent Behavior Letter, 1999.

    ERIC Educational Resources Information Center

    Lipsitt, Lewis P., Ed.

    1999-01-01

    These 12 monthly issues from 1999 explore problems encountered by children and adolescents. Regular features include "Keep Your Eye On...," brief accounts of research into childhood and adolescent problems; "What's New in Research," summarizing research from recent publications and professional conferences;…

  5. CCRC Currents. April 2010

    ERIC Educational Resources Information Center

    Slater, Doug, Ed.

    2010-01-01

    This annual newsletter contains updates on the latest Community College Research Center (CCRC) research, new publications and details of upcoming presentations at major conferences. The feature article in this issue, "The Growing Prominence of Community Colleges," by Thomas Bailey, discusses how today's community colleges are increasingly…

  6. Wilderness Medicine Newsletter, Volume 8.

    ERIC Educational Resources Information Center

    Weber, Holly A., Ed.

    1997-01-01

    This document consists of the six issues of the "Wilderness Medicine Newsletter" published during 1997. The newsletter provides medical and rescue information for the non-physician in remote wilderness areas. Issues typically include feature articles, conference and training courses schedules, an "Ask the Expert" column, and…

  7. Organization Values. Symposium 10. [AHRD Conference, 2001].

    ERIC Educational Resources Information Center

    2001

    This document contains three papers on organizational values. "Understanding the Work Beliefs of Nonprofit Executives through Organizational Stories" (Ava S. Wilensky, Carol D. Hansen) reports on a study during which qualitative interviews featuring a story component established that nonprofit executives constitute a diffuse managerial…

  8. Lunar and Planetary Information Bulletin. No. 95

    NASA Technical Reports Server (NTRS)

    Schenk, Paul M. (Editor)

    2003-01-01

    The articles in this issue cover the end of the Galileo mission to Jupiter, educational outreach programs, and news on planetary science, including discoveries and updates on Mars missions. This issue also features brief book reviews, and a calender listing conferences for 2003.

  9. The Brown University Child and Adolescent Behavior Letter, 1998.

    ERIC Educational Resources Information Center

    Lipsitt, Lewis P., Ed.

    1998-01-01

    These 12 monthly issues from 1998 explore problems encountered by children and adolescents. Regular features include "Keep Your Eye On...," brief accounts of research into childhood and adolescent problems, "What's New in Research," summarizing research from recent publications and professional conferences;…

  10. ISMB/ECCB 2009 Stockholm

    PubMed Central

    Sagot, Marie-France; McKay, B.J. Morrison; Myers, Gene

    2009-01-01

    The International Society for Computational Biology (ISCB; http://www.iscb.org) presents the Seventeenth Annual International Conference on Intelligent Systems for Molecular Biology (ISMB), organized jointly with the Eighth Annual European Conference on Computational Biology (ECCB; http://bioinf.mpi-inf.mpg.de/conferences/eccb/eccb.htm), in Stockholm, Sweden, 27 June to 2 July 2009. The organizers are putting the finishing touches on the year's premier computational biology conference, with an expected attendance of 1400 computer scientists, mathematicians, statisticians, biologists and scientists from other disciplines related to and reliant on this multi-disciplinary science. ISMB/ECCB 2009 (http://www.iscb.org/ismbeccb2009/) follows the framework introduced at the ISMB/ECCB 2007 (http://www.iscb.org/ismbeccb2007/) in Vienna, and further refined at the ISMB 2008 (http://www.iscb.org/ismb2008/) in Toronto; a framework developed to specifically encourage increased participation from often under-represented disciplines at conferences on computational biology. During the main ISMB conference dates of 29 June to 2 July, keynote talks from highly regarded scientists, including ISCB Award winners, are the featured presentations that bring all attendees together twice a day. The remainder of each day offers a carefully balanced selection of parallel sessions to choose from: proceedings papers, special sessions on emerging topics, highlights of the past year's published research, special interest group meetings, technology demonstrations, workshops and several unique sessions of value to the broad audience of students, faculty and industry researchers. Several hundred posters displayed for the duration of the conference has become a standard of the ISMB and ECCB conference series, and an extensive commercial exhibition showcases the latest bioinformatics publications, software, hardware and services available on the market today. The main conference is preceded by 2 days of Special Interest Group (SIG) and Satellite meetings running in parallel to the fifth Student Council Symposium on 27 June, and in parallel to Tutorials on 28 June. All scientific sessions take place at the Stockholmsmässan/Stockholm International Fairs conference and exposition facility. Contact: bj@iscb.org PMID:19447790

  11. Biomimetic Nanofibrillation in Two-Component Biopolymer Blends with Structural Analogs to Spider Silk

    NASA Astrophysics Data System (ADS)

    Xie, Lan; Xu, Huan; Li, Liang-Bin; Hsiao, Benjamin S.; Zhong, Gan-Ji; Li, Zhong-Ming

    2016-10-01

    Despite the enormous potential in bioinspired fabrication of high-strength structure by mimicking the spinning process of spider silk, currently accessible routes (e.g., microfluidic and electrospinning approaches) still have substantial function gaps in providing precision control over the nanofibrillar superstructure, crystalline morphology or molecular orientation. Here the concept of biomimetic nanofibrillation, by copying the spiders’ spinning principles, was conceived to build silk-mimicking hierarchies in two-phase biodegradable blends, strategically involving the stepwise integration of elongational shear and high-pressure shear. Phase separation confined on nanoscale, together with deformation of discrete phases and pre-alignment of polymer chains, was triggered in the elongational shear, conferring the readiness for direct nanofibrillation in the latter shearing stage. The orderly aligned nanofibrils, featuring an ultralow diameter of around 100 nm and the “rigid-soft” system crosslinked by nanocrystal domains like silk protein dopes, were secreted by fine nanochannels. The incorporation of multiscale silk-mimicking structures afforded exceptional combination of strength, ductility and toughness for the nanofibrillar polymer composites. The proposed spider spinning-mimicking strategy, offering the biomimetic function integration unattainable with current approaches, may prompt materials scientists to pursue biopolymer mimics of silk with high performance yet light weight.

  12. Biomimetic Nanofibrillation in Two-Component Biopolymer Blends with Structural Analogs to Spider Silk.

    PubMed

    Xie, Lan; Xu, Huan; Li, Liang-Bin; Hsiao, Benjamin S; Zhong, Gan-Ji; Li, Zhong-Ming

    2016-10-03

    Despite the enormous potential in bioinspired fabrication of high-strength structure by mimicking the spinning process of spider silk, currently accessible routes (e.g., microfluidic and electrospinning approaches) still have substantial function gaps in providing precision control over the nanofibrillar superstructure, crystalline morphology or molecular orientation. Here the concept of biomimetic nanofibrillation, by copying the spiders' spinning principles, was conceived to build silk-mimicking hierarchies in two-phase biodegradable blends, strategically involving the stepwise integration of elongational shear and high-pressure shear. Phase separation confined on nanoscale, together with deformation of discrete phases and pre-alignment of polymer chains, was triggered in the elongational shear, conferring the readiness for direct nanofibrillation in the latter shearing stage. The orderly aligned nanofibrils, featuring an ultralow diameter of around 100 nm and the "rigid-soft" system crosslinked by nanocrystal domains like silk protein dopes, were secreted by fine nanochannels. The incorporation of multiscale silk-mimicking structures afforded exceptional combination of strength, ductility and toughness for the nanofibrillar polymer composites. The proposed spider spinning-mimicking strategy, offering the biomimetic function integration unattainable with current approaches, may prompt materials scientists to pursue biopolymer mimics of silk with high performance yet light weight.

  13. Mutagenicity in a Molecule: Identification of Core Structural Features of Mutagenicity Using a Scaffold Analysis

    PubMed Central

    Hsu, Kuo-Hsiang; Su, Bo-Han; Tu, Yi-Shu; Lin, Olivia A.; Tseng, Yufeng J.

    2016-01-01

    With advances in the development and application of Ames mutagenicity in silico prediction tools, the International Conference on Harmonisation (ICH) has amended its M7 guideline to reflect the use of such prediction models for the detection of mutagenic activity in early drug safety evaluation processes. Since current Ames mutagenicity prediction tools only focus on functional group alerts or side chain modifications of an analog series, these tools are unable to identify mutagenicity derived from core structures or specific scaffolds of a compound. In this study, a large collection of 6512 compounds are used to perform scaffold tree analysis. By relating different scaffolds on constructed scaffold trees with Ames mutagenicity, four major and one minor novel mutagenic groups of scaffold are identified. The recognized mutagenic groups of scaffold can serve as a guide for medicinal chemists to prevent the development of potentially mutagenic therapeutic agents in early drug design or development phases, by modifying the core structures of mutagenic compounds to form non-mutagenic compounds. In addition, five series of substructures are provided as recommendations, for direct modification of potentially mutagenic scaffolds to decrease associated mutagenic activities. PMID:26863515

  14. Biomimetic Nanofibrillation in Two-Component Biopolymer Blends with Structural Analogs to Spider Silk

    PubMed Central

    Xie, Lan; Xu, Huan; Li, Liang-Bin; Hsiao, Benjamin S.; Zhong, Gan-Ji; Li, Zhong-Ming

    2016-01-01

    Despite the enormous potential in bioinspired fabrication of high-strength structure by mimicking the spinning process of spider silk, currently accessible routes (e.g., microfluidic and electrospinning approaches) still have substantial function gaps in providing precision control over the nanofibrillar superstructure, crystalline morphology or molecular orientation. Here the concept of biomimetic nanofibrillation, by copying the spiders’ spinning principles, was conceived to build silk-mimicking hierarchies in two-phase biodegradable blends, strategically involving the stepwise integration of elongational shear and high-pressure shear. Phase separation confined on nanoscale, together with deformation of discrete phases and pre-alignment of polymer chains, was triggered in the elongational shear, conferring the readiness for direct nanofibrillation in the latter shearing stage. The orderly aligned nanofibrils, featuring an ultralow diameter of around 100 nm and the “rigid−soft” system crosslinked by nanocrystal domains like silk protein dopes, were secreted by fine nanochannels. The incorporation of multiscale silk-mimicking structures afforded exceptional combination of strength, ductility and toughness for the nanofibrillar polymer composites. The proposed spider spinning-mimicking strategy, offering the biomimetic function integration unattainable with current approaches, may prompt materials scientists to pursue biopolymer mimics of silk with high performance yet light weight. PMID:27694989

  15. Proceedings of the conference on metropolitan physical environment

    Treesearch

    Gordon M. Heisler; Lee P. Herrington

    1977-01-01

    A report on the conference held in August 1975 at Syracuse, N.Y., containing 50 papers presented at the meeting, at which some 160 scientists and scholars discussed the use of vegetation, space, and structures to improve the amenities for people who live in metropolitan areas.

  16. Conference Report: ESF-COST High-Level Research Conference Natural Products Chemistry, Biology and Medicine III.

    PubMed

    Catino, Arthur

    2010-12-01

    Natural Products Chemistry, Biology and Medicine III was the third conference in a series of events sponsored by the European Science Foundation (ESF) and the European Cooperation in the field of Scientific and Technical Research (COST). Scientists came together from within and outside the EU to present cutting-edge developments in chemical synthesis. Research areas included the synthesis of natural products, methods development, isolation/structural elucidation and chemical biology. As our capacity to produce new chemotherapeutic agents relies on chemical synthesis, this year's conference has never been so timely. This report highlights several of the scientific contributions presented during the meeting.

  17. New Features in the ADS Abstract Service

    NASA Astrophysics Data System (ADS)

    Eichhorn, G.; Accomazzi, A.; Grant, C. S.; Kurtz, M. J.; ReyBacaicoa, V.; Murray, S. S.

    2001-11-01

    The ADS Abstract Service contains over 2.3 million references in four databases: Astronomy/Astrophysics/Planetary Sciences, Instrumentation, Physics/Geophysics, and Preprints. We provide abstracts and articles free to the astronomical community for all major and many smaller astronomy journals, PhD theses, conference proceedings, and technical reports. These four databases can be queried either separately of jointly. The ADS also has scanned 1.3 million pages in 180,000 articles in the ADS Article Service. This literature archive contains all major Astronomy journals and many smaller journals, as well as conference proceedings, including the abstract books from all the LPSCs back to volume 2. A new feature gives our users the ability to see list of articles that were also read by the readers of a given article. This is a powerful tool to find out what current articles are relevant in a particular field of study. We have recently expanded the citation and reference query capabilities. It allows our users to select papers for which they want to see references or citations and then retrieve these citations/references. Another new capability is the ability to sort a list of articles by their citation count. As usual, users should be reminded that the citations in ADS are incomplete because we do not obtain reference lists from all publishers. In addition, we cannot match all references (e.g. in press, private communications, author errors, some conference papers, etc.). Anyone using the citations for analysis of publishing records should keep this in mind. More work on expanding the citation and reference features is planned over the next year. ADS Home Page http://ads.harvard.edu/

  18. 2012 Gordon Research Conference, Mitochondria and Chloroplasts, July 29 - Aug 3 2012

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barkan, Alice

    2012-08-03

    The 2012 Gordon Research Conference on Mitochondria and Chloroplasts will assemble an international group of scientists investigating fundamental properties of these organelles, and their integration into broader physiological processes. The conference will emphasize the many commonalities between mitochondria and chloroplasts: their evolution from bacterial endosymbionts, their genomes and gene expression systems, their energy transducing membranes whose proteins derive from both nuclear and organellar genes, the challenge of maintaining organelle integrity in the presence of the reactive oxygen species that are generated during energy transduction, their incorporation into organismal signaling pathways, and more. The conference will bring together investigators working inmore » animal, plant, fungal and protozoan systems who specialize in cell biology, genetics, biochemistry, physiology, proteomics, genomics, and structural biology. As such, this conference will provide a unique forum that engenders cross-disciplinary discussions concerning the biogenesis, dynamics, and regulation of these key cellular structures. By fostering interactions among mammalian, fungal and plant organellar biologists, this conference also provides a conduit for the transmission of mechanistic insights obtained in model organisms to applications in medicine and agriculture. The 2012 conference will highlight areas that are moving rapidly and emerging themes. These include new insights into the ultrastructure and organization of the energy transducing membranes, the coupling of organellar gene expression with the assembly of photosynthetic and respiratory complexes, the regulatory networks that couple organelle biogenesis with developmental and physiological signals, the signaling events through which organellar physiology influences nuclear gene expression, and the roles of organelles in disease and development.« less

  19. Preface: Proceedings of the 13th Conference on Liquid and Amorphous Metals (LAM13) (Ekaterinburg, Russia, 8 14 July 2007)

    NASA Astrophysics Data System (ADS)

    Popel, Pjotr; Gelchinskii, Boris; Sidorov, Valeriy

    2008-03-01

    The most recent developments in the field of liquid and amorphous metals and alloys are regularly updated through two complementary international conferences: the liquid and amorphous metals conference (LAM) and the rapidly quenched materials (RQ) conference. The first series of conferences started as LM1 in 1966 at Brookhaven for the basic understanding of liquid metals. The subsequent LM conferences were held in Tokyo (1972) and Bristol (1976). The conference was renewed in Grenoble (1980) as a LAM conference including amorphous metals and continued in Los Angeles (1983), Garmisch-Partenkirchen (1986), Kyoto (1989), Vienna (1992), Chicago (1995), Dortmund (1998), Yokohama (2001) and Metz (2004). The conferences are mainly devoted to liquid and amorphous metals and alloys. However, communications on some non-metallic systems such as semiconductors, quasicrystals etc, are also accepted. The conference tradition strongly encourages participation from junior researchers and graduate students. The 13th conference of the LAM series was organized in Ekaterinburg, Russia, by the Institute of Metallurgy of the Ural Branch of the Russian Academy of Sciences (IMet UB RAS) and the Ural State Pedagogical University (USPU), and held from 8-14 July 2007 under the chairmanship of Professors Pjotr Popel (USPU) and Boris Gelchinskii (IMet UB RAS). Two hundred and forty two active participants and about 60 guest participants from 20 countries attended the conference. There were no parallel sessions and all oral reports were separated into three groups: invited talks (40 min), full-scale oral reports (25 min), and brief oral reports (15 min). The program included ten sessions, ranging from purely theoretical subjects to the technological application of molten and amorphous alloys. The following sessions took place: A: Electronic structure and transport, magnetic properties; B: Phase transitions; C: Structure; D: Atomic dynamics and transport; E: Thermodynamics; F: Modelling, simulation; G: Surface and interface; H: Mechanical properties and new materials; I: Quasicrystals; J: Industrial applications. The largest sessions were E, C, D and F with 53, 47, 43 and 40 reports, respectively. Posters were exhibited during the first (sessions A-E) or last (sessions F-J) three days of the conference. As usual, each oral session started with an invited talk. In accordance with contemporary tendencies the first invited talk of M Yao (Kyoto University) was devoted to interrelations between liquid metal studies and nanoscience. He pointed out that the physics of disordered matter, especially liquid metals, has provided nanoscience with basic ideas and theoretical tools such as ab initio molecular dynamics (MD) simulation. K Tamura (Kyoto University) reported experimental investigation results of expanded liquid rubidium, showing that observed structural features are originated from the instability of low-density electron gas. Modern theory has predicted that interacting electron gas suffers negative compressibility and the static dielectric function (DF) becomes negative when electron density is sufficiently reduced. Negative DF is of special interest when considering the possibility of new types of superconductors. In the next invited lecture, M I Mendelev and J R Morris (USA) described how MD simulations were performed to study phase transformations in supercooled liquid Al. The authors found that the widely used EAM potential for Al enables vitrification for cooling rates achievable in classical MD simulation, while other Al potentials enable crystallization under the same conditions. The reason for this difference was discussed, as well as features of vitrification in the EA Al. P Häussler (Chemnitz Univeristy) spoke about fundamental structure-forming processes in liquid and amorphous materials. He proposed the resonance model as an autonomous missing link between the microscopic description of atoms/molecules of Schrödinger's equation, and crystals, where global concepts such as planar resonances exist and Bloch's theorem is applied. D Holland-Moritz (Institut für Materialphysik, Köln) presented the first results of the quasielastic neutron scattering experiments on electromagnetically levitated metallic melts. The studies were indicative of Arrhenius behavior of the diffusion constants over the whole temperature regime investigated, ranging from temperatures above the melting temperature up to the metastable regime of an undercooled liquid. L Son (USPU) discussed the existing analytical theories of liquid-liquid phase transitions that have been assumed for a wide variety of liquids, but are poorly understood analytically. The application of these theories to liquid metal systems was also demonstrated. An approach to the study of dynamics and kinetics of cavitation in stretched liquid metals by the classical MD method was presented in the talk of G E Norman (Institute for High Temperatures, Moscow). Both quantitative and qualitative disagreements with the classic theory of homogeneous nucleation were found. Analytic extentions of MD results beyond the space and temporal limits accessible for the MD method were also discussed. G Wilde (University of Muenster) spoke about the experimental investigation into the impact of interface properties and, more specifically, of interface morphology in matrix-encased metallic nanoparticles on macroscopic properties, such as melting transition by a combination of microscopic, microanalytical and calorimetric measurements. The results were discussed with respect to the underlying mechanisms that lead to size dependent phase equilibria. In the invited talk of V Keryvin (University of Rennes) the indentation ability was proposed as a probe for pressure sensitivity in metallic glasses. The main conclusion was that the indentation test provides a good means to study the elasto-plastic behavior of these materials as well as being a relevant tool to subject metallic glasses to multiaxial loadings. The influence of changes in local ordering of precursor melt on the formation of the amorphous state and subsequent crystallization was the subject of a report presented by P Śvec (Institute of Physics, Bratislava). The effect was shown for a rapidly quenched Fe-Mo-B system with addition of Cu and substitution of Fe by Co prepared under varying conditions of planar flow casting and using master alloys with specific melt treatment. Approximately 320 abstracts were received and 180 manuscripts were finally submitted for publication. Papers from invited lectures and full-scale oral reports are published in Journal of Physics: Condensed Matter for this special issue. All papers from brief oral reports and posters were collected for an issue of Journal of Physics: Conference Series. All were edited by staff from Ekaterinburg. It was decided during the joint meeting of both the International Advisory Board and International Program Committee that the next conference in the LAM series, LAM14, will be arranged by the groups of A Di Cicco (Camerino University) and T Scopigno (University of Rome 'La Sapienza'), and will take place in Rome, Italy, in 2010. It is no easy task to outline new scientific tendencies in the field of liquid and amorphous alloys just after the LAM conference. It takes one or two years to estimate the significance of the event. Only one conclusion is obvious: the LAM13 conference has opened a door between the global scientific community and Russian scientists, who have special expertise in the field but could not actively participate at the LAM conferences before because of the economic situation in Russia. We are grateful to the Advisory and Program Committees of the LAM12 conference in Metz and especially to Dr Monique Calvo-Dahlborg for the opportunity to manage such an event in Russia. In addition we would like to give our sincere thanks to: the authorities of the Ural Branch of the Russian Academy of Sciences and the Ural State Pedagogical University who did their best to help us with all our problems, especially to Boris Igoshev and Nikolay Vatolin; all the sponsors who supported the conference: the Russian Foundation for Basic Research, the Ural Mining and Metallurgical Company headed by Andrey Kozicyn, the Open Joint Stock Company 'Uralsvjazinform' (Alexey Ufimkin), the A A Baikov Institute of Metallurgy and Materials Science, RAS (July Kovneristii), the Institute for Physics and Power Engineering (Alexandre Ephanov), the Nuclear Power Plant 'Beloyarskaya' (Nikolay Oshkanov), the South Ural State University (German Vjatkin), Ural Technical Institute of Communications and Informatics (Evgeny Subbotin), Physical-Technical Institute UB RAS (Vladimir Lad'yanov), Metallurgical Department of the Ural State Technical University (Victor Shimov), Academy of Sciences of Chechen Republic (Raikom Dadashev) and NETZSCH-Gerätebau GmbH; the invited lecturers who immediately answered positively to the invitation and contributed to the high level of success of LAM13; the colleagues who acted as chairmen in the various sessions; Graham Douglas and Richard Palmer who kindly answered our queries and tried to satisfy our requirements; the seniors of the LAM series who could not participate at the 13th conference but helped us to manage it in the best way, namely J Dupuy, M Silbert, F Sommer, W C Pilgrim, W Freyland, K Lu, J Brmejo and F Hensel. We dedicate the LAM13 conference to the 80 year jubilee of Professor Nikolay Vatolin who is one of the leaders of Russian investigation in the field of liquid and amorphous metals, and who managed 12 similar conferences in our country. One of us (PP) commemorates his father, Professor Stanislav Popel, who was a known specialist in high temperature capillarity and sadly left us six months before the event.

  20. Label-free NIR reflectance imaging as a complimentary tool for two-photon fluorescence microscopy: multimodal investigation of stroke (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Allegra Mascaro, Anna Letizia; Costantini, Irene; Margoni, Emilia; Iannello, Giulio; Bria, Alessandro; Sacconi, Leonardo; Pavone, Francesco S.

    2016-03-01

    Two-photon imaging combined with targeted fluorescent indicators is extensively used for visualizing critical features of brain functionality and structural plasticity. Back-scattered photons from the NIR laser provide complimentary information without introducing any exogenous labelling. Here, we describe a versatile approach that, by collecting the reflected NIR light, provides structural details on the myelinated axons and blood vessels in the brain, both in fixed samples and in live animals. Indeed, by combining NIR reflectance and two-photon imaging of a slice of hippocampus from Thy1-GFPm mice, we show the presence of randomly oriented axons intermingled with sparsely fluorescent neuronal processes. The back-scattered photons guide the contextualization of the fluorescence structure within brain atlas thanks to the recognition of characteristic hippocampal structures. Label-free detection of axonal elongations over the layer 2/3 of mouse cortex under a cranial window was also possible in live brain. Finally, blood flow could be measured in vivo, thus validating label free NIR reflectance as a tool for monitoring hemodynamic fluctuations. The prospective versatility of this label-free technique complimentary to two-photon fluorescence microscopy is demonstrated in a mouse model of photothrombotic stroke in which the axonal degeneration and blood flow remodeling can be investigated simultaneously.

  1. Lung texture in serial thoracic CT scans: correlation with radiologist-defined severity of acute changes following radiation therapy

    NASA Astrophysics Data System (ADS)

    Cunliffe, Alexandra R.; Armato, Samuel G., III; Straus, Christopher; Malik, Renuka; Al-Hallaq, Hania A.

    2014-09-01

    This study examines the correlation between the radiologist-defined severity of normal tissue damage following radiation therapy (RT) for lung cancer treatment and a set of mathematical descriptors of computed tomography (CT) scan texture (‘texture features’). A pre-therapy CT scan and a post-therapy CT scan were retrospectively collected under IRB approval for each of the 25 patients who underwent definitive RT (median dose: 66 Gy). Sixty regions of interest (ROIs) were automatically identified in the non-cancerous lung tissue of each post-therapy scan. A radiologist compared post-therapy scan ROIs with pre-therapy scans and categorized each as containing no abnormality, mild abnormality, moderate abnormality, or severe abnormality. Twenty texture features that characterize gray-level intensity, region morphology, and gray-level distribution were calculated in post-therapy scan ROIs and compared with anatomically matched ROIs in the pre-therapy scan. Linear regression and receiver operating characteristic (ROC) analysis were used to compare the percent feature value change (ΔFV) between ROIs at each category of visible radiation damage. Most ROIs contained no (65%) or mild abnormality (30%). ROIs with moderate (3%) or severe (2%) abnormalities were observed in 9 patients. For 19 of 20 features, ΔFV was significantly different among severity levels. For 12 features, significant differences were observed at every level. Compared with regions with no abnormalities, ΔFV for these 12 features increased, on average, by 1.5%, 12%, and 30%, respectively, for mild, moderate, and severe abnormalitites. Area under the ROC curve was largest when comparing ΔFV in the highest severity level with the remaining three categories (mean AUC across features: 0.84). In conclusion, 19 features that characterized the severity of radiologic changes from pre-therapy scans were identified. These features may be used in future studies to quantify acute normal lung tissue damage following RT. Presented, in part at the IASLC 15th World Conference on Lung Conference, Sydney, AUS (2013).

  2. HBCUs/OMUs Research Conference Agenda and Abstracts

    NASA Technical Reports Server (NTRS)

    Dutta, Sunil (Compiler)

    2000-01-01

    The purpose of this Historically Black Colleges and Universities (HBCUs) Research Conference was to provide an opportunity for principal investigators and their students to present research progress reports. The Abstracts included in this report indicate the range and quality of research topics such as aeropropulsion, space propulsion, space power, fluid dynamics, designs, structures and materials being funded through grants from Glenn Research Center to HBCUs. The conference generated extensive networking between students, principal investigators, Glenn technical monitors, and other Glenn researchers.

  3. HBCUs/OMUs Research Conference Agenda and Abstracts

    NASA Technical Reports Server (NTRS)

    Dutta, Sunil (Compiler)

    2003-01-01

    The purpose of this Historically Black Colleges and Universities (HBCUs/OMUs) Research Conference was to provide an opportunity for principal investigators and their students to present research progress reports. The abstracts included in this report indicate the range and quality of research topics such as aeropropulsion, space propulsion, space power, fluid dynamics, designs, structures and materials being funded through grants from Glenn Research Center to HBCUs. The conference generated extensive networking between students, principal investigators, Glenn technical monitors, and other Glenn researchers.

  4. HBCUs/OMUs Research Conference Agenda and Abstracts

    NASA Technical Reports Server (NTRS)

    Dutta, Sunil (Compiler)

    2001-01-01

    The purpose of this Historically Black Colleges and Universities (HBCUs) Research Conference was to provide an opportunity for principal investigators and their students to present research progress reports. The abstracts included in this report indicate the range and quality of research topics such as aeropropulsion, space propulsion, space power, fluid dynamics, designs, structures and materials being funded through grants from Glenn Research Center to HBCUs. The conference generated extensive networking between students, principal investigators, Glenn technical monitors, and other Glenn researchers.

  5. Mechanics of Textile Composites Conference

    NASA Technical Reports Server (NTRS)

    Poe, Clarence C. (Editor); Harris, Charles E. (Editor)

    1995-01-01

    This document is a compilation of papers presented at the Mechanics of Textile Composites Conference in Hampton, Virginia, December 6-8, 1994. This conference was the culmination of a 3-year program that was initiated by NASA late in 1990 to develop mechanics of textile composites in support of the NASA Advance Composites Technology Program (ACT). The goal of the program was to develop mathematical models of textile preform materials and test methods to facilitate structural analysis and design. Participants in the program were from NASA, academia, and industry.

  6. Show & Tell. Proceedings of the Ontario Universities' Conference (1st, Guelph, Canada, May 1987).

    ERIC Educational Resources Information Center

    Herrmann, Thom, Ed.

    Twenty-three conference papers focus on the use of information technology in Ontario's technical colleges and universities: "The Analytic Criticism Module--Authorial Structures & Design" (P. Beam); "Computing by Design" (R. D. Brown & J. D. Milliken); "Engineers and Computers" (P. S. Chisholm, M. Iwaniw, and…

  7. Developing Graduate Attributes through Participation in Undergraduate Research Conferences

    ERIC Educational Resources Information Center

    Hill, Jennifer; Walkington, Helen

    2016-01-01

    Graduate attributes are a framework of skills, attitudes, values and knowledge that graduates should develop by the end of their degree programmes. Adopting a largely qualitative approach and using semi-structured interviews, this paper outlines students' experiences at a national undergraduate research conference over three years and evidences…

  8. Meeting Education Challenges in the Information Age.

    ERIC Educational Resources Information Center

    Turk, Judy VanSlyke; Botan, Carl; Morreale, Sherwyn P.

    1999-01-01

    Outlines briefly the history of this special issue on education in public relations, noting that its articles represent summaries of the work and findings of the National Communication Association 1998 Summer Conference. Notes the structure of the task force and task teams which carried out the work of the conference. (SR)

  9. Open Mind Conference

    NASA Technical Reports Server (NTRS)

    King, Alexander H.

    1995-01-01

    Open Mind, The Association for the achievement of diversity in higher education, met in conference in Albuquerque, New Mexico, between October 16 and 18, 1992. A number of workgroups met to discuss the goals, structure, and generally evaluate the Association and its achievements. A summary of the workgroup sessions and their minutes are included.

  10. Guidelines for competency development and measurement in rehabilitation psychology postdoctoral training.

    PubMed

    Stiers, William; Barisa, Mark; Stucky, Kirk; Pawlowski, Carey; Van Tubbergen, Marie; Turner, Aaron P; Hibbard, Mary; Caplan, Bruce

    2015-05-01

    This study describes the results of a multidisciplinary conference (the Baltimore Conference) that met to develop consensus guidelines for competency specification and measurement in postdoctoral training in rehabilitation psychology. Forty-six conference participants were chosen to include representatives of rehabilitation psychology training and practice communities, representatives of psychology accreditation and certification bodies, persons involved in medical education practice and research, and consumers of training programs (students). Consensus education and training guidelines were developed that specify the key competencies in rehabilitation psychology postdoctoral training, and structured observation checklists were developed for their measurement. This study continues the development of more than 50 years of thinking about education and training in rehabilitation psychology and builds on the existing work to further advance the development of guidelines in this area. The conference developed aspirational guidelines for competency specification and measurement in rehabilitation psychology postdoctoral training (i.e., for studying the outcomes of these training programs). Structured observation of trainee competencies allows examination of actual training outcomes in relation to intended outcomes and provides a methodology for studying how program outcomes are related to program structures and processes so that program improvement can occur. Best practices in applying program evaluation research methods to the study of professional training programs are discussed. (c) 2015 APA, all rights reserved).

  11. XML Tactical Chat (XTC): The Way Ahead for Navy Chat

    DTIC Science & Technology

    2007-09-01

    multicast transmissions via sophisticated pruning algorithms, while allowing multicast packets to “ tunnel ” through IP routers. [Macedonia, Brutzman 1994...conference was Jabber Inc. who added some great insight into the power of Jabber. • Great features including blackberry handheld connectivity and

  12. National Center for Family Literacy, 1994.

    ERIC Educational Resources Information Center

    NCFL Newsletter, 1994

    1994-01-01

    These four newsletter issues provide information on family literacy and literacy education programs. Each 16-page issue includes several feature articles; descriptions of literacy conferences and seminars; updates on the National Family Literacy Project; descriptions of successful family literacy programs; coming events; a list of National Center…

  13. Wilderness Medicine Newsletter, Volume 5.

    ERIC Educational Resources Information Center

    Wilderness Medicine Newsletter, 1994

    1994-01-01

    This volume of newsletters addresses issues related to the treatment and prevention of medical emergencies in the wilderness. Each issue includes feature articles, book reviews, product reviews, letters to the editor, notices of upcoming wilderness conferences and training courses, additional resources, and general information relevant to medical…

  14. The Teacher Trainer, 2001.

    ERIC Educational Resources Information Center

    Woodward, Tessa, Ed.

    2001-01-01

    This journal is designed as a forum for trainers, teachers, and trainees all over the world. Regular features include the following: "Conference Report"; "Process Options"; "People Who Train People"; "Training around the World"; "Session Report"; "Trainee Voices"; "Current Research"; "Just for Interest"; "A Trainer Like Me"; "Trainer Background";…

  15. Electron Technology - ELTE 2013

    NASA Astrophysics Data System (ADS)

    Szczepański, Paweł; Kisiel, Ryszard; Romaniuk, Ryszard S.

    2013-07-01

    The paper presents a digest of chosen research and technical work results shown by researchers from technical universities, governmental institutes and research firms during the XIth Scientific Conference on Electron Technology ELTE 2013. ELTE Conference has been held every three years since more than three decades. The ELTE 2013 conference was held in Ryn Castle (Poland) on 16-20 April 2013 and gathered around 270 scientists, theoreticians, technologists and engineers from such areas as material engineering, chemistry, sensors, integrated circuits, electronics engineering, laser industry, photonics, etc. The conference featured the following major four topical sessions - Micro and Nano, Photonics, Materials and Technologies, and Microsystems; two dedicated sessions - a keynote plenary session on hot topics in electron technology, as well as a session on large research projects and grants realized by the relevant community. Oral topical sessions were accompanied by poster sessions. The paper is a succinct topical introduction to the volume of ELTE 2013 proceedings. Over 100 papers, gathered in the volume, present a very relevant cross section and state-of-the-art of this branch of science and technology in Poland with involved international co-operation.

  16. Drug resistance conferred by mutations outside the active site through alterations in the dynamic and structural ensemble of HIV-1 protease.

    PubMed

    Ragland, Debra A; Nalivaika, Ellen A; Nalam, Madhavi N L; Prachanronarong, Kristina L; Cao, Hong; Bandaranayake, Rajintha M; Cai, Yufeng; Kurt-Yilmaz, Nese; Schiffer, Celia A

    2014-08-27

    HIV-1 protease inhibitors are part of the highly active antiretroviral therapy effectively used in the treatment of HIV infection and AIDS. Darunavir (DRV) is the most potent of these inhibitors, soliciting drug resistance only when a complex combination of mutations occur both inside and outside the protease active site. With few exceptions, the role of mutations outside the active site in conferring resistance remains largely elusive. Through a series of DRV-protease complex crystal structures, inhibition assays, and molecular dynamics simulations, we find that single and double site mutations outside the active site often associated with DRV resistance alter the structure and dynamic ensemble of HIV-1 protease active site. These alterations correlate with the observed inhibitor binding affinities for the mutants, and suggest a network hypothesis on how the effect of distal mutations are propagated to pivotal residues at the active site and may contribute to conferring drug resistance.

  17. Prototypes for Content-Based Image Retrieval in Clinical Practice

    PubMed Central

    Depeursinge, Adrien; Fischer, Benedikt; Müller, Henning; Deserno, Thomas M

    2011-01-01

    Content-based image retrieval (CBIR) has been proposed as key technology for computer-aided diagnostics (CAD). This paper reviews the state of the art and future challenges in CBIR for CAD applied to clinical practice. We define applicability to clinical practice by having recently demonstrated the CBIR system on one of the CAD demonstration workshops held at international conferences, such as SPIE Medical Imaging, CARS, SIIM, RSNA, and IEEE ISBI. From 2009 to 2011, the programs of CADdemo@CARS and the CAD Demonstration Workshop at SPIE Medical Imaging were sought for the key word “retrieval” in the title. The systems identified were analyzed and compared according to the hierarchy of gaps for CBIR systems. In total, 70 software demonstrations were analyzed. 5 systems were identified meeting the criterions. The fields of application are (i) bone age assessment, (ii) bone fractures, (iii) interstitial lung diseases, and (iv) mammography. Bridging the particular gaps of semantics, feature extraction, feature structure, and evaluation have been addressed most frequently. In specific application domains, CBIR technology is available for clinical practice. While system development has mainly focused on bridging content and feature gaps, performance and usability have become increasingly important. The evaluation must be based on a larger set of reference data, and workflow integration must be achieved before CBIR-CAD is really established in clinical practice. PMID:21892374

  18. Proceedings of the Annual Conference on Technology and Innovations in Training and Education (9th)

    DTIC Science & Technology

    1991-01-01

    training features. Figure 15 illustrates community well. The push and the training system features pull of interactivity, as well analysis process. Note that...offers a restructuring of its staff to balance the number of pull down menus that enable a user to easily create technical staff members with the...Merlin lessons using a series of "preformatted templates" Objetive number which negates the need to actually use Merlin code. It offers pull down menus

  19. Science and technology for the 21. century: Meeting the needs of the global community

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1994-12-31

    This report summarizes the organization, activities and outcomes of Student Pugwash USA`s 1994 International Conference, Science and Technology for the 21st Century: Meeting the Needs of the Global Community. The Conference was held June 12--18, 1994 at Johns Hopkins University in Baltimore, Maryland, and brought together 91 students from 25 countries and over 65 experts from industry, academy, and government. Student Pugwash USA`s International Conference provided a valuable forum for talented students and professionals to engage in critical dialogue on many interdisciplinary issues at the junction of science, technology and society. The 1994 International Conference challenged students--the world`s future scientists,more » engineers, and political leaders--to think broadly about global problems and to devise policy options that are viable and innovative. In addition to afternoon and evening plenary sessions, six working groups met each morning of the Conference week. The working group themes featured: preventive diplomacy and conflict resolution for a secure future; resource stewardship for environmental sustainability; the social costs and medical benefits of human genetic information; overcoming barriers to health care education and delivery; meeting societal needs through communication and information technologies; and designing the future--from corporations to communities.« less

  20. Genetics of hybrid male sterility among strains and species in the Drosophila pseudoobscura species group

    PubMed Central

    McDermott, Shannon R.; Noor, Mohamed A. F.

    2011-01-01

    Taxa in the early stages of speciation may bear intraspecific allelic variation at loci conferring barrier traits in hybrids such as hybrid sterility. Additionally, hybridization may spread alleles that confer barrier traits to other taxa. Historically, few studies examine within- and between-species variation at loci conferring reproductive isolation. Here, we test for allelic variation within Drosophila persimilis and within the Bogota subspecies of D. pseudoobscura at regions previously shown to contribute to hybrid male sterility. We also test whether D. persimilis and the USA subspecies of D. pseudoobscura share an allele conferring hybrid sterility in a D. pseudoobscura bogotana genetic background. All loci conferred similar hybrid sterility effects across all strains studied, though we detected some statistically significant quantitative effect variation among D. persimilis alleles of some hybrid incompatibility QTLs. We also detected allelism between D. persimilis and D. pseudoobscura USA at a 2nd chromosome hybrid sterility QTL. We hypothesize that either the QTL is ancestral in D. persimilis and D. pseudoobscura USA and lost in D. pseudoobscura bogotana, or gene flow transferred the QTL from D. persimilis to D. pseudoobscura USA. We discuss our findings in the context of population features that may contribute to variation in hybrid incompatibilities. PMID:21729052

  1. Genetics of hybrid male sterility among strains and species in the Drosophila pseudoobscura species group.

    PubMed

    McDermott, Shannon R; Noor, Mohamed A F

    2011-07-01

    Taxa in the early stages of speciation may bear intraspecific allelic variation at loci conferring barrier traits in hybrids such as hybrid sterility. Additionally, hybridization may spread alleles that confer barrier traits to other taxa. Historically, few studies examine within- and between-species variation at loci conferring reproductive isolation. Here, we test for allelic variation within Drosophila persimilis and within the Bogota subspecies of D. pseudoobscura at regions previously shown to contribute to hybrid male sterility. We also test whether D. persimilis and the USA subspecies of D. pseudoobscura share an allele conferring hybrid sterility in a D. pseudoobscura bogotana genetic background. All loci conferred similar hybrid sterility effects across all strains studied, although we detected some statistically significant quantitative effect variation among D. persimilis alleles of some hybrid incompatibility QTLs. We also detected allelism between D. persimilis and D. pseudoobscura USA at a second chromosome hybrid sterility QTL. We hypothesize that either the QTL is ancestral in D. persimilis and D. pseudoobscura USA and lost in D. pseudoobscura bogotana, or gene flow transferred the QTL from D. persimilis to D. pseudoobscura USA. We discuss our findings in the context of population features that may contribute to variation in hybrid incompatibilities. © 2011 The Author(s). Evolution© 2011 The Society for the Study of Evolution.

  2. The World Health Organisation 2016 classification of penile carcinomas: a review and update from the International Society of Urological Pathology expert-driven recommendations.

    PubMed

    Cubilla, Antonio L; Velazquez, Elsa F; Amin, Mahul B; Epstein, Jonathan; Berney, Daniel M; Corbishley, Cathy M

    2018-05-01

    The International Society of Urological Pathology (ISUP) held an expert-driven penile cancer conference in Boston in March 2015, which focused on the new World Health Organisation (WHO) classification of penile cancer: human papillomavirus (HPV)-related tumours and histological grading. The conference was preceded by an online survey of the ISUP members, and the results were used to initiate discussions. Because of the rarity of penile tumours, this was not a consensus but an expert-driven conference aimed at assisting pathologists who do not see these tumours on a regular basis. After a justification for the novel separation of penile squamous cell carcinomas into HPV-related and non-HPV-related-carcinomas, the histological classification of penile carcinoma was proposed; this system was also accepted subsequently by the WHO for subtyping of penile carcinomas (2016). A description of HPV-related neoplasms, which may be recognised by their histological features, was presented, and p16 was recommended as a surrogate indicator of HPV. A three-tier grading system was recommended for penile squamous carcinomas; this was also adopted by the WHO (2016). Many of the distinctive histological subtypes of squamous cell carcinoma of the penis are associated with distinct grades, based on the squamous cell carcinoma subtype histological features. © 2017 John Wiley & Sons Ltd.

  3. 2011 Vascular Research Initiatives Conference: basic foundations of translational research in vascular disease.

    PubMed

    Ziegler, Kenneth R; Dardik, Alan

    2011-07-01

    The Vascular Research Initiatives Conference (VRIC) is an annual conference organized by the Society for Vascular Surgery (SVS). The 2011 VRIC was held in Chicago (IL, USA) to precede and coincide with the first day of the meeting of the Council on Arteriosclerosis, Thrombosis and Vascular Biology (ATVB) of the American Heart Association. The event is designed to present world class vascular research results, encourage collaboration between vascular surgeons and basic scientists in related disciplines, as well as to stimulate interest in research among aspiring academic vascular surgeons. The 2011 VRIC featured plenary sessions addressing peripheral arterial disease, vascular endothelium and thrombosis, aneurysms, and stem cells and tissue engineering. Recipients of the SVS partner grants with the National Institutes of Health K08 awardees presented their progress reports, and keynote addresses were given by Linda Graham and Frank LoGerfo.

  4. Preface: Electromagnetic and Light Scattering by Nonspherical Particles XIV

    NASA Technical Reports Server (NTRS)

    Dubovik, Oleg; Labonnete, Laurent; Litvinov, Pavel; Parol, Frederic; Mischenko, Michael

    2014-01-01

    The 14th Electromagnetic and Light Scattering Conference (ELS-XIV) was held at the Universit de Lille 1, Villeneuve d'Ascq, France on 17-21 June 2013. The conference was attended by 200 scientists from 26 countries. The scientific program included one plenary lecture, 12 invited reviews, 100 contributed oral talks, and 86 poster presentations. The program, the abstracts, and the slides of the oral presentations are available at the conference web site http:www-loa.univ-lille1.frELS-XIV. To highlight one of the traditional ELS themes, the ELS-XIV featured a special session on Remote sensing of aerosols and clouds using polarimetric observations. This session was sponsored and co-organized by the French space agency CNES and attracted representatives from nearly all research teams word-wide involved in the development and active use of space-borne, in situ, and ground-based polarimetric observations.

  5. A novel algorithm for delineating wetland depressions and ...

    EPA Pesticide Factsheets

    In traditional watershed delineation and topographic modeling, surface depressions are generally treated as spurious features and simply removed from a digital elevation model (DEM) to enforce flow continuity of water across the topographic surface to the watershed outlets. In reality, however, many depressions in the DEM are actual wetland landscape features that are seldom fully filled with water. For instance, wetland depressions in the Prairie Pothole Region (PPR) are seasonally to permanently flooded wetlands characterized by nested hierarchical structures with dynamic filling- spilling-merging surface-water hydrological processes. The objectives of this study were to delineate hierarchical wetland catchments and model their hydrologic connectivity using high-resolution LiDAR data and aerial imagery. We proposed a novel algorithm delineate the hierarchical wetland catchments and characterize their geometric and topological properties. Potential hydrologic connectivity between wetlands and streams were simulated using the least-cost path algorithm. The resulting flow network delineated putative temporary or seasonal flow paths connecting wetland depressions to each other or to the river network at scales finer than available through the National Hydrography Dataset. The results demonstrated that our proposed framework is promising for improving overland flow modeling and hydrologic connectivity analysis. Presentation at AWRA Spring Specialty Conference in Sn

  6. Anisotropy of the Seebeck Coefficient in the Cuprate Superconductor YBa2 Cu3 Oy : Fermi-Surface Reconstruction by Bidirectional Charge Order

    NASA Astrophysics Data System (ADS)

    Cyr-Choinière, O.; Badoux, S.; Grissonnanche, G.; Michon, B.; Afshar, S. A. A.; Fortier, S.; LeBoeuf, D.; Graf, D.; Day, J.; Bonn, D. A.; Hardy, W. N.; Liang, R.; Doiron-Leyraud, N.; Taillefer, Louis

    2017-07-01

    The Seebeck coefficient S of the cuprate YBa2 Cu3 Oy is measured in magnetic fields large enough to suppress superconductivity, at hole dopings p =0.11 and p =0.12 , for heat currents along the a and b directions of the orthorhombic crystal structure. For both directions, S /T decreases and becomes negative at low temperature, a signature that the Fermi surface undergoes a reconstruction due to broken translational symmetry. Above a clear threshold field, a strong new feature appears in Sb, for conduction along the b axis only. We attribute this feature to the onset of 3D-coherent unidirectional charge-density-wave modulations seen by x-ray diffraction, also along the b axis only. Because these modulations have a sharp onset temperature well below the temperature where S /T starts to drop towards negative values, we infer that they are not the cause of Fermi-surface reconstruction. Instead, the reconstruction must be caused by the quasi-2D bidirectional modulations that develop at significantly higher temperature. The unidirectional order only confers an additional anisotropy to the already reconstructed Fermi surface, also manifest as an in-plane anisotropy of the resistivity.

  7. Responses of auditory-cortex neurons to structural features of natural sounds.

    PubMed

    Nelken, I; Rotman, Y; Bar Yosef, O

    1999-01-14

    Sound-processing strategies that use the highly non-random structure of natural sounds may confer evolutionary advantage to many species. Auditory processing of natural sounds has been studied almost exclusively in the context of species-specific vocalizations, although these form only a small part of the acoustic biotope. To study the relationships between properties of natural soundscapes and neuronal processing mechanisms in the auditory system, we analysed sound from a range of different environments. Here we show that for many non-animal sounds and background mixtures of animal sounds, energy in different frequency bands is coherently modulated. Co-modulation of different frequency bands in background noise facilitates the detection of tones in noise by humans, a phenomenon known as co-modulation masking release (CMR). We show that co-modulation also improves the ability of auditory-cortex neurons to detect tones in noise, and we propose that this property of auditory neurons may underlie behavioural CMR. This correspondence may represent an adaptation of the auditory system for the use of an attribute of natural sounds to facilitate real-world processing tasks.

  8. Discovering the intelligence in molecular biology.

    PubMed

    Uberbacher, E

    1995-12-01

    The Third International Conference on Intelligent Systems in Molecular Biology was truly an outstanding event. Computational methods in molecular biology have reached a new level of maturity and utility, resulting in many high-impact applications. The success of this meeting bodes well for the rapid and continuing development of computational methods, intelligent systems and information-based approaches for the biosciences. The basic technology, originally most often applied to 'feasibility' problems, is now dealing effectively with the most difficult real-world problems. Significant progress has been made in understanding protein-structure information, structural classification, and how functional information and the relevant features of active-site geometry can be gleaned from structures by automated computational approaches. The value and limits of homology-based methods, and the ability to classify proteins by structure in the absence of homology, have reached a new level of sophistication. New methods for covariation analysis in the folding of large structures such as RNAs have shown remarkably good results, indicating the long-term potential to understand very complicated molecules and multimolecular complexes using computational means. Novel methods, such as HMMs, context-free grammars and the uses of mutual information theory, have taken center stage as highly valuable tools in our quest to represent and characterize biological information. A focus on creative uses of intelligent systems technologies and the trend toward biological application will undoubtedly continue and grow at the 1996 ISMB meeting in St Louis.

  9. Expansion of the aminoglycoside-resistance 16S rRNA (m(1)A1408) methyltransferase family: expression and functional characterization of four hypothetical enzymes of diverse bacterial origin.

    PubMed

    Witek, Marta A; Conn, Graeme L

    2014-09-01

    The global dissemination, potential activity in diverse species and broad resistance spectrum conferred by the aminoglycoside-resistance ribosomal RNA methyltransferases make them a significant potential new threat to the efficacy of aminoglycoside antibiotics in the treatment of serious bacterial infections. The N1 methylation of adenosine 1408 (m(1)A1408) confers resistance to structurally diverse aminoglycosides, including kanamycin, neomycin and apramycin. The limited analyses to date of the enzymes responsible have identified common features but also potential differences in their molecular details of action. Therefore, with the goal of expanding the known 16S rRNA (m(1)A1408) methyltransferase family as a platform for developing a more complete mechanistic understanding, we report here the cloning, expression and functional analyses of four hypothetical aminoglycoside-resistance rRNA methyltransferases from recent genome sequences of diverse bacterial species. Each of the genes produced a soluble, folded protein with a secondary structure, as determined from circular dichroism (CD) spectra, consistent with enzymes for which high-resolution structures are available. For each enzyme, antibiotic minimum inhibitory concentration (MIC) assays revealed a resistance spectrum characteristic of the known 16S rRNA (m(1)A1408) methyltransferases and the modified nucleotide was confirmed by reverse transcription as A1408. In common with other family members, higher binding affinity for the methylation reaction by-product S-adenosylhomocysteine (SAH) than the cosubstrate S-adenosyl-L-methionine (SAM) was observed for three methyltransferases, while one unexpectedly showed no measurable affinity for SAH. Collectively, these results confirm that each hypothetical enzyme is a functional 16S rRNA (m(1)A1408) methyltransferase but also point to further potential mechanistic variation within this enzyme family. Copyright © 2014 Elsevier B.V. All rights reserved.

  10. 76 FR 15988 - National Institute of Mental Health; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-22

    ... U.S.C. App.), notice is hereby given of an Interagency Autism Coordinating Committee (IACC) meeting. The meeting will feature special presentations and activities to celebrate HHS Autism Awareness Month... conference call. Name of Committee: Interagency Autism Coordinating Committee (IACC). Type of meeting: Open...

  11. The CARE International Evaluation Standards

    ERIC Educational Resources Information Center

    Rugh, Jim

    2004-01-01

    The 1996 American Evaluation Association conference in Atlanta featured a session on strategies to promote monitoring and evaluation (M&E) in international nongovernmental organizations (INGOs). At that time, there was a lengthy list of proposed initiatives to be undertaken in CARE. With the perspective of hindsight and reviewing the…

  12. Wilderness Medicine Newsletter, 1993.

    ERIC Educational Resources Information Center

    Wilderness Medicine Newsletter, 1993

    1993-01-01

    This volume of a newsletter focused on the treatment and prevention of medical emergencies in the wilderness contains all six issues for the year 1993. Issues include feature articles, book reviews, product reviews, letters to the editor, notices of upcoming wilderness conferences and training courses, additional resources, and general information…

  13. Forecast of the World's Electrical Demands until 2025.

    ERIC Educational Resources Information Center

    Claverie, Maurice J.; Dupas, Alain P.

    1979-01-01

    Models of global energy demand, a lower-growth-rate model developed at Case Western Reserve University and the H5 model of the Conservation Committee of the World Energy Conference, assess the features of decentralized and centralized electricity generation in the years 2000 and 2025. (BT)

  14. MN GIS/LIS Consortium Annual Conference and Workshops, Rochester, MN, October 1-3, 2014

    EPA Science Inventory

    We mapped the distribution of multiple ecosystem services in the Saint Louis River Area of Concern (SLR AOC) under current and reported extreme lake levels. Services were mapped using measured or modeled natural features (i.e., bathymetry, vegetation, fetch, habitat, contaminated...

  15. Ethics of Gene Therapy Debated.

    ERIC Educational Resources Information Center

    Borman, Stu

    1991-01-01

    Presented are the highlights of a press conference featuring biomedical ethicist LeRoy Walters of Georgetown University and attorney Andrew Kimbrell of the Foundation on Economic Trends. The opposing points of view of these two speakers serve to outline the pros and cons of the gene therapy issue. (CW)

  16. Message from the Conference Chairs

    NASA Astrophysics Data System (ADS)

    Krishna, Sanjay; Perera, Unil

    2015-05-01

    We were very excited to host the 8th International Workshop on Quantum Structure Infrared Photodetectors (QSIP 2014), in picturesque Santa Fe, New Mexico from June 29th-July 3rd, 2014. This followed successful QSIP conferences at Dana Point (2000), Torino (2002), Kananaskis (2004), Kandy (2006), Yosimite (2009), Istanbul (2010) and Corsica (2012). The QSIP workshop is a high level scientific conference that aims to bring together scientists, engineers, industrial organizations, students and users in order to discuss recent advances, and to share the "State of the Art" in this field. QSIP conferences provide an international forum for attendees to present and discuss progress in infrared device physics and modeling, materials growth and processing issues, focal plane array development and characterization.

  17. Centaurus A: Source Populations in the Nearest Bright Elliptical

    NASA Technical Reports Server (NTRS)

    Mushotzky, Richard (Technical Monitor); Murray, Stephen S.

    2003-01-01

    The XMM/Newton observations of the nearby radio galaxy, Centaurus A, have proven to be a rich data set and has given us new insights into several important processes present in Centaurus A. A list of publications, conference proceedings, and conference abstracts related to these data are attached at the end of this document. We have used the XMM/Newton observations to study the interaction between the relativistic, radio emitting plasma emitted from active nuclei with the hot interstellar medium. Centaurus A is the nearest radio galaxy, so that we have been able to study these features at a linear resolution unattainable for any similar object.

  18. Energy in the '80s: a call for leadership

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1981-07-01

    The theme of this conference - Energy in the '80s: A Call for Leadership - was selected to focus attention on what was believed to be what America needs now - to get on with the tasks at hand. This proceedings of the Public Awareness Symposium, held on February 19, featured six speakers; the address of Senator Jackson at the banquet on February 20, which concluded the conference is also included; a separate abstract was prepared for each of these seven presentations. Also, the society-sponsored technical session papers are listed in Appendix A, and the Engineering/Communication scholarships are noted inmore » Appendix B.« less

  19. Library activities in the U.S. and the Western Europe : Trends and features in the recent information management system

    NASA Astrophysics Data System (ADS)

    Takayama, Masaya

    This author reports the discussion and resolutions from the annual meeting of the Special Libraries Association at New York City in the U.S. and the General Conference of the International Federation of Library Associations and Institutions at Paris in France in 1989. Moreover this author visited American libraries after the S.L.A.meeting, and French and British libraries after the IFLA Conference. Based on these library tours, this author concludes that Japanese librarians and information specialists need to know the needs of the application of new information network technologies to the routine works of information management in Japan.

  20. 77 FR 44674 - Solicitation for a Cooperative Agreement-National Institute of Corrections Inaugural Virtual...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-30

    ..., scheduling, promotion, production, and delivery of an NIC Virtual Conference entitled ``Handcuff Key to Door... conference through design, scheduling, promotion, and delivery; (2) In-studio and/or onsite production staff... in a project plan a detailed chart and description of a project management structure and team roles...

  1. Using a Professional Conference Model to Teach Adolescents about School-Age Parenthood.

    ERIC Educational Resources Information Center

    Schilmoeller, Gary L.; And Others

    Although information regarding the consequences of adolescent pregnancy and childbirth is disseminated, the recipients of that information are most often adults. To present this information directly to never-pregnant adolescents, an annual conference, outside of the authority structure of the school was developed in Bangor, Maine. The three…

  2. Apollo 11 Lunar Science Conference

    ERIC Educational Resources Information Center

    Cochran, Wendell

    1970-01-01

    Report of a conference called to discuss the findings of 142 scientists from their investigations of samples of lunar rock and soil brought back by the Apollo 11 mission. Significant findings reported include the age and composition of the lunar samples, and the absence of water and organic matter. Much discussed was the origin and structure of…

  3. International Conference of Applied Science and Technology for Infrastructure Engineering

    NASA Astrophysics Data System (ADS)

    Elvina Santoso, Shelvy; Hardianto, Ekky

    2017-11-01

    Preface: International Conference of Applied Science and Technology for Infrastructure Engineering (ICASIE) 2017. The International Conference of Applied Science and Technology for Infrastructure Engineering (ICASIE) 2017 has been scheduled and successfully taken place at Swiss-Bell Inn Hotel, Surabaya, Indonesia, on August 5th 2017 organized by Department of Civil Infrastructure Engineering, Faculty of Vocation, Institut Teknologi Sepuluh Nopember (ITS). This annual event aims to create synergies between government, private sectors; employers; practitioners; and academics. This conference has different theme each year and “MATERIAL FOR INFRASTUCTURE ENGINEERING” will be taken for this year’s main theme. In addition, we also provide a platform for various other sub-theme topic including but not limited to Geopolymer Concrete and Materials Technology, Structural Dynamics, Engineering, and Sustainability, Seismic Design and Control of Structural Vibrations, Innovative and Green Buildings, Project Management, Transportation and Highway Engineering, Geotechnical Engineering, Water Engineering and Resources Management, Surveying and Geospatial Engineering, Coastal Engineering, Geophysics, Energy, Electronic and Mechatronic, Industrial Process, and Data Mining. List of Organizers, Journal Editors, Steering Committee, International Scientific Committee, Chairman, Keynote Speakers are available in this pdf.

  4. Clinical skin imaging using color spatial frequency domain imaging (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Yang, Bin; Lesicko, John; Moy, Austin J.; Reichenberg, Jason; Tunnell, James W.

    2016-02-01

    Skin diseases are typically associated with underlying biochemical and structural changes compared with normal tissues, which alter the optical properties of the skin lesions, such as tissue absorption and scattering. Although widely used in dermatology clinics, conventional dermatoscopes don't have the ability to selectively image tissue absorption and scattering, which may limit its diagnostic power. Here we report a novel clinical skin imaging technique called color spatial frequency domain imaging (cSFDI) which enhances contrast by rendering color spatial frequency domain (SFD) image at high spatial frequency. Moreover, by tuning spatial frequency, we can obtain both absorption weighted and scattering weighted images. We developed a handheld imaging system specifically for clinical skin imaging. The flexible configuration of the system allows for better access to skin lesions in hard-to-reach regions. A total of 48 lesions from 31 patients were imaged under 470nm, 530nm and 655nm illumination at a spatial frequency of 0.6mm^(-1). The SFD reflectance images at 470nm, 530nm and 655nm were assigned to blue (B), green (G) and red (R) channels to render a color SFD image. Our results indicated that color SFD images at f=0.6mm-1 revealed properties that were not seen in standard color images. Structural features were enhanced and absorption features were reduced, which helped to identify the sources of the contrast. This imaging technique provides additional insights into skin lesions and may better assist clinical diagnosis.

  5. First clinical pilot study with intravascular polarization sensitive optical coherence tomography (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Villiger, Martin; Karanasos, Antonios; Ren, Jian; Lippok, Norman; Shishkov, Milen; Daemen, Joost; Van Mieghem, Nicolas; Diletti, Roberto; Valgimigli, Marco; van Geuns, Robert-Jan; de Jaegere, Peter; Zijlstra, Felix; van Soest, Gijs; Nadkarni, Seemantini; Regar, Evelyn; Bouma, Brett E.

    2016-02-01

    Polarization sensitive (PS) OCT measures the polarization states of the light backscattered by tissue and provides measures of tissue birefringence and depolarization in addition to the structural OCT signal. Ex vivo studies have demonstrated that birefringence is increased in tissue rich in collagen and with elevated smooth muscle cell content. Preliminary data further suggests that depolarization can identify regions of macrophage infiltration, lipid, and irregularly arranged collagen fibers. These are important aspects of the mechanical integrity and vulnerability of atherosclerotic plaques. To evaluate the potential of PS-OCT in the clinical setting, we combined our custom PS-OCT system with commercially available OCT catheters (Fastview, Terumo Corporation) and performed a pilot study in 30 patients, scheduled to undergo percutaneous coronary intervention (PCI) on the grounds of stable or unstable angina. A total of 82 pullbacks in 39 vessels were performed, either in the native coronary arteries or post procedure. Comparing consecutive pullbacks of the same coronary artery, we found excellent agreement between the polarization features in the repeat pullbacks, validating the repeatability and robustness of PS-OCT in the clinical in vivo setting. In addition we observed that the birefringence and depolarization features vary significantly across lesions with identical structural OCT appearance, suggesting morphological subtypes. This first human pilot study proved the feasibility and robustness of intravascular PS-OCT. PS-OCT achieves improved tissue characterization and may help in identifying high-risk plaques, with the potential to ultimately improve risk stratification and help guiding PCI.

  6. Twitter expands the reach and engagement of a national scientific meeting: the Irish Society of Urology.

    PubMed

    Nason, G J; O'Kelly, F; Bouchier-Hayes, D; Quinlan, D M; Manecksha, R P

    2015-09-01

    Social media is the interaction among people in which they create, share or exchange information and ideas in virtual communities and web-based networks. This year, the Irish Society of Urology (ISU) expanded its involvement in social media with a preregistered Twitter hashtag (#ISU14) for the annual meeting. The aim of this study was to highlight the use of Twitter at an annual national meeting held in 2014. The Symplur healthcare analytics website was used to prospectively examine traffic related to the 2014 ISU Annual Meeting. This feature was used to generate statistics for the number of impressions, unique tweets (excluding retweets) and distinct contributors who used the indexing hashtag #ISU14. Individual tweets were assessed using the conference hashtag on the Twitter website. The total number of attendees at the conference was 119, and 99 individuals participated in Twitter using the conference hashtag (#ISU14). 31 % of attendees participated in tweeting at the conference. Over the course of the conference, a total of 798 unique tweets were generated, creating over 665,000 impressions in cyberspace. 590 (73.9 %) tweets were generated from attendees at the conference, while 26.1 % of tweets were from virtual followers. 702 (87.9 %) tweets were from urologists and 439 (55 %) tweets were of scientific nature. Tweet activity peaked during the guest lectures on both days. Twitter use at the ISU has been shown to facilitate interaction between delegates and allows users to follow as well as participate from afar.

  7. Comments by the Chairman

    NASA Astrophysics Data System (ADS)

    Fouillat, Pascal

    2013-08-01

    The European Conference on Radiation and its Effects on Components and Systems (RADECS 2012) was held on September 24-28, 2012, in Biarritz, France. The latest advances in the field of radiation effects on electronic and photonic materials, devices, circuits, sensors, and systems, were presented and discussed. The conference featured a Technical Program, an Industrial Exhibit, and one day meeting on radiation ground effects held on September 24 (RADGROUND). The conference gathered 390 attendees, scientists and engineers from 26 countries, with a high participation of France (101), USA (80), Russia (50), Spain (28), Germany (28), and U.K. (25). Raoul Velazco, from TIMA Labs, was in charge of the Technical Program, assisted by a Technical Program Committee listed below and a pool ofmore than 150 reviewers which contributed maintain the high level of quality reached since many years by the RADECS conferences. The total number of contributions reached 201 and each paper received at least four reviews. There were 145 papers accepted and presented in the Oral Sessions (48), Poster Sessions (69), and Data Workshop (28). The scope of the conference encompassed technological processes and design techniques for producing radiation tolerant systems for space, aeronautical or terrestrial applications, as well as relevant methodologies for their characterization and qualification. The Conference Record, gathering all the papers compliant with IEEE quality standards and editorial rules, is available through the IEEE Xplore Digital Library. The paper candidates and selected for publication in the IEEE TRANSACTIONS ON NUCLEAR SCIENCE will be published in this special issue.

  8. Proceedings of Naval Facilities Engineering Command Ocean Engineering Conference Held at Washington DC on 23-25 September 1969

    DTIC Science & Technology

    1969-09-01

    use a "plucking" process rather than a pruning " process with our established projects. In this way, the im- portant projects will be accomplished in...Enger, CEC, USN, Commander, NAVFAC 1000-1015 "Ocean Engineering Capt. W.A. Walls Policies" 1015-1030 Coffee Break 1030-1045 Conference Objectives Dr...of Structures a. SEALAB b. TEKTITE Dr. J.D. Stachiw, NCEL c. Concrete Structures D. Potter, NAVFAC d. Penetrations 0945-1000 Coffee Break 1000-1100 e

  9. XA23 is an executor R protein and confers broad-spectrum disease resistance in rice.

    PubMed

    Wang, Chunlian; Zhang, Xiaoping; Fan, Yinglun; Gao, Ying; Zhu, Qinlong; Zheng, Chongke; Qin, Tengfei; Li, Yanqiang; Che, Jinying; Zhang, Mingwei; Yang, Bing; Liu, Yaoguang; Zhao, Kaijun

    2015-02-01

    The majority of plant disease resistance (R) genes encode proteins that share common structural features. However, the transcription activator-like effector (TALE)-associated executor type R genes show no considerable sequence homology to any known R genes. We adopted a map-based cloning approach and TALE-based technology to isolate and characterize Xa23, a new executor R gene derived from wild rice (Oryza rufipogon) that confers an extremely broad spectrum of resistance to bacterial blight caused by Xanthomonas oryzae pv. oryzae (Xoo). Xa23 encodes a 113 amino acid protein that shares 50% identity with the known executor R protein XA10. The predicted transmembrane helices in XA23 also overlap with those of XA10. Unlike Xa10, however, Xa23 transcription is specifically activated by AvrXa23, a TALE present in all examined Xoo field isolates. Moreover, the susceptible xa23 allele has an identical open reading frame of Xa23 but differs in promoter region by lacking the TALE binding element (EBE) for AvrXa23. XA23 can trigger a strong hypersensitive response in rice, tobacco, and tomato. Our results provide the first evidence that plant genomes have an executor R gene family of which members execute their function and spectrum of disease resistance by recognizing the cognate TALEs in the pathogen. Copyright © 2015 The Author. Published by Elsevier Inc. All rights reserved.

  10. Increasing Capacity for Innovation in Bureaucratic Primary Care Organizations: A Whole System Participatory Action Research Project

    PubMed Central

    Thomas, Paul; McDonnell, Juliet; McCulloch, Janette; While, Alison; Bosanquet, Nick; Ferlie, Ewan

    2005-01-01

    PURPOSE We wanted to identify what organizational features support innovation in Primary Care Groups (PCGs). METHODS Our study used a whole system participatory action research model. Four research teams provided complementary insights. Four case study PCGs were analyzed. Two had an intervention to help local facilitators reflect on their work. Data included 70 key informant interviews, observations of clinical governance interventions and committee meetings, analysis of written materials, surveys and telephone interviews of London Primary Care Organizations, interviews with 20 nurses, and interviews with 6 finance directors. A broad range of stakeholders reviewed data at annual conferences and formed conclusions about trustworthy principles. Sequential research phases were refocused in the light of these conclusions and in response to the changing political context. RESULTS Five features were associated with increased organizational capacity for innovation: (1) clear structures and a vision for corporate and clinical governance; (2) multiple opportunities for people to reflect and learn at all levels of the organization, and connections between these “learning spaces”; (3) both clinicians and managers in leadership roles that encourage participation; (4) the right timing for an initiative and its adaptation to the local context; and (5) external facilitation that provides opportunities for people to make sense of their experiences. Low morale was commonly attributed to 3 features: (1) overwhelming pace of reform, (2) inadequate staff experience and supportive infrastructure, and (3) financial deficits. CONCLUSIONS These features together may support innovation in other primary care bureaucracies. The research methodology enabled people from different backgrounds to make sense of diverse research insights. PMID:16046563

  11. Increasing capacity for innovation in bureaucratic primary care organizations: a whole system participatory action research project.

    PubMed

    Thomas, Paul; McDonnell, Juliet; McCulloch, Janette; While, Alison; Bosanquet, Nick; Ferlie, Ewan

    2005-01-01

    We wanted to identify what organizational features support innovation in Primary Care Groups (PCGs). Our study used a whole system participatory action research model. Four research teams provided complementary insights. Four case study PCGs were analyzed. Two had an intervention to help local facilitators reflect on their work. Data included 70 key informant interviews, observations of clinical governance interventions and committee meetings, analysis of written materials, surveys and telephone interviews of London Primary Care Organizations, interviews with 20 nurses, and interviews with 6 finance directors. A broad range of stakeholders reviewed data at annual conferences and formed conclusions about trustworthy principles. Sequential research phases were refocused in the light of these conclusions and in response to the changing political context. Five features were associated with increased organizational capacity for innovation: (1) clear structures and a vision for corporate and clinical governance; (2) multiple opportunities for people to reflect and learn at all levels of the organization, and connections between these "learning spaces"; (3) both clinicians and managers in leadership roles that encourage participation; (4) the right timing for an initiative and its adaptation to the local context; and (5) external facilitation that provides opportunities for people to make sense of their experiences. Low morale was commonly attributed to 3 features: (1) overwhelming pace of reform, (2) inadequate staff experience and supportive infrastructure, and (3) financial deficits. These features together may support innovation in other primary care bureaucracies. The research methodology enabled people from different backgrounds to make sense of diverse research insights.

  12. Regional conferences--a capacity-building mandate: report on CRCP2011-Building Bridges and Building a Regional Structure.

    PubMed

    Thompson, Ava; Bernal, Guillermo; Dudley-Grant, Rita; Govia, Ishtar; Nicolas, Guerda; Bullock, Merry; Gauthier, Janel

    2013-01-01

    The Caribbean Regional Conference of Psychology was held in Nassau, The Bahamas, from 15 to 18 November 2011, under the auspices of the International Association of Applied Psychology (IAAP), the International Union of Psychological Science (IUPsyS), and the International Association for Cross-Cultural Psychology (IACCP). The conference was hosted by the Bahamas Psychological Association, and organized by a committee chaired by Dr Ava Thompson, College of the Bahamas. The CRCP2011 attracted over 400 participants from 37 countries, including 20 nations/territories in the Caribbean. A broad scientific program, organized around six conference themes, addressed strengths and challenges to psychology in the region; the current state of psychological research, assessment, and intervention; historical, cultural, and language influences; and links between Caribbean and global models. Conference outcomes included planning for a series of publications to expand on conference themes and presentations, as well as establishment of a steering group to launch a regional organization to support the science and practice of psychology in the Caribbean.

  13. Virtual viewpoint synthesis in multi-view video system

    NASA Astrophysics Data System (ADS)

    Li, Fang; Yang, Shiqiang

    2005-07-01

    In this paper, we present a virtual viewpoint video synthesis algorithm to satisfy the following three aims: low computing consuming; real time interpolation and acceptable video quality. In contrast with previous technologies, this method obtain incompletely 3D structure using neighbor video sources instead of getting total 3D information with all video sources, so that the computation is reduced greatly. So we demonstrate our interactive multi-view video synthesis algorithm in a personal computer. Furthermore, adopting the method of choosing feature points to build the correspondence between the frames captured by neighbor cameras, we need not require camera calibration. Finally, our method can be used when the angle between neighbor cameras is 25-30 degrees that it is much larger than common computer vision experiments. In this way, our method can be applied into many applications such as sports live, video conference, etc.

  14. What is a good medical decision? A research agenda guided by perspectives from multiple stakeholders.

    PubMed

    Hamilton, Jada G; Lillie, Sarah E; Alden, Dana L; Scherer, Laura; Oser, Megan; Rini, Christine; Tanaka, Miho; Baleix, John; Brewster, Mikki; Craddock Lee, Simon; Goldstein, Mary K; Jacobson, Robert M; Myers, Ronald E; Zikmund-Fisher, Brian J; Waters, Erika A

    2017-02-01

    Informed and shared decision making are critical aspects of patient-centered care, which has contributed to an emphasis on decision support interventions to promote good medical decision making. However, researchers and healthcare providers have not reached a consensus on what defines a good decision, nor how to evaluate it. This position paper, informed by conference sessions featuring diverse stakeholders held at the 2015 Society of Behavioral Medicine and Society for Medical Decision Making annual meetings, describes key concepts that influence the decision making process itself and that may change what it means to make a good decision: interpersonal factors, structural constraints, affective influences, and values clarification methods. This paper also proposes specific research questions within each of these priority areas, with the goal of moving medical decision making research to a more comprehensive definition of a good medical decision, and enhancing the ability to measure and improve the decision making process.

  15. In vitro DNA SCRaMbLE.

    PubMed

    Wu, Yi; Zhu, Rui-Ying; Mitchell, Leslie A; Ma, Lu; Liu, Rui; Zhao, Meng; Jia, Bin; Xu, Hui; Li, Yun-Xiang; Yang, Zu-Ming; Ma, Yuan; Li, Xia; Liu, Hong; Liu, Duo; Xiao, Wen-Hai; Zhou, Xiao; Li, Bing-Zhi; Yuan, Ying-Jin; Boeke, Jef D

    2018-05-22

    The power of synthetic biology has enabled the expression of heterologous pathways in cells, as well as genome-scale synthesis projects. The complexity of biological networks makes rational de novo design a grand challenge. Introducing features that confer genetic flexibility is a powerful strategy for downstream engineering. Here we develop an in vitro method of DNA library construction based on structural variation to accomplish this goal. The "in vitro SCRaMbLE system" uses Cre recombinase mixed in a test tube with purified DNA encoding multiple loxPsym sites. Using a β-carotene pathway designed for expression in yeast as an example, we demonstrate top-down and bottom-up in vitro SCRaMbLE, enabling optimization of biosynthetic pathway flux via the rearrangement of relevant transcription units. We show that our system provides a straightforward way to correlate phenotype and genotype and is potentially amenable to biochemical optimization in ways that the in vivo system cannot achieve.

  16. Hyperphagia: current concepts and future directions proceedings of the 2nd international conference on hyperphagia

    USDA-ARS?s Scientific Manuscript database

    Hyperphagia is a central feature of inherited disorders (e.g., Prader-Willi Syndrome) in which obesity is a primary phenotypic component. Hyperphagia may also contribute to obesity as observed in the general population, thus raising the potential importance of common underlying mechanisms and treatm...

  17. DCIs, SEPs, and CCs, Oh My! Understanding the Three Dimensions of the NGSS

    ERIC Educational Resources Information Center

    Duncan, Ravit Golan; Cavera, Veronica L.

    2015-01-01

    The "Next Generation Science Standards'" three dimensions--disciplinary core ideas (DCIs), science and engineering practices (SEPs), and crosscutting concepts (CCs)--were headliners at NSTA's national conference in Chicago and featured in many of the organization's other professional-development efforts this year (NGSS Lead States 2013).…

  18. Articulating Domestic and Global University Descriptors and Indices of Excellence

    ERIC Educational Resources Information Center

    Lindsay, Beverly

    2012-01-01

    At the 2010 American Educational Research Association (AERA) annual conference, a featured invited session focused on "How professors think: inside the curious world of academic judgment." Harvard University professor and author, Michele Lamont, articulated a thoughtful precis of her book. Her material concentrates on the "curious" world of…

  19. Introduction to the Special Issue on Innovative Applications of Artificial Intelligence 2014

    DOE PAGES

    Stracuzzi, David J.; Gunning, David

    2015-09-28

    This issue features expanded versions of articles selected from the 2014 AAAI Conference on Innovative Applications of Artificial Intelligence held in Quebec City, Canada. We present a selection of four articles describing deployed applications plus two more articles that discuss work on emerging applications.

  20. Proceedings, Conference on the Computing Environment for Mathematical Software

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Recent advances in software and hardware technology which make it economical to create computing environments appropriate for specialized applications are addressed. Topics included software tools, FORTRAN standards activity, and features of languages, operating systems, and hardware that are important for the development, testing, and maintenance of mathematical software.

  1. NONROAD2005 Training Presentation Slides, May 2006 15th International Emission Inventory Conference (New Orleans)

    EPA Pesticide Factsheets

    Learn about the 2005 update to the NONROAD emissions inventory model and its features and outputs, including hands-on exercises. Keep in mind that the most current model, approved for use in SIPs, is MOVES2014a which absorbed the latest NONROAD model.

  2. Introduction to the Special Issue on Innovative Applications of Artificial Intelligence 2014

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stracuzzi, David J.; Gunning, David

    This issue features expanded versions of articles selected from the 2014 AAAI Conference on Innovative Applications of Artificial Intelligence held in Quebec City, Canada. We present a selection of four articles describing deployed applications plus two more articles that discuss work on emerging applications.

  3. The 2011 North American strawberry symposium: an introduction

    USDA-ARS?s Scientific Manuscript database

    The 2011 Symposium was held in conjunction with the 32nd North American Strawberry Growers Association (NASGA) Annual Conference on 8-11 Feb. 2011, at the Doubletree Hotel in Tampa, FL. The scientific program was conducted over two days and featured five sessions of oral and poster presentations sp...

  4. Systems Librarian and Automation Review.

    ERIC Educational Resources Information Center

    Schuyler, Michael

    1992-01-01

    Discusses software sharing on computer networks and the need for proper bandwidth; and describes the technology behind FidoNet, a computer network made up of electronic bulletin boards. Network features highlighted include front-end mailers, Zone Mail Hour, Nodelist, NetMail, EchoMail, computer conferences, tosser and scanner programs, and host…

  5. Proceedings of the NASA/Florida Institute of Technology Environmental Engineering Conference on Nitrogen Tetroxide. [with emphasis on space shuttle

    NASA Technical Reports Server (NTRS)

    Rhodes, E. L.

    1978-01-01

    Methods of reducing the user hazards of nitrogen tetroxide, a hypergolic oxidizer are discussed. Kennedy Space Center developments in N2O4 control for the space shuttle are featured. Other areas covered are life support equipment and transportation.

  6. Innovations in Early Education: The International Reggio Exchange, 2000-2001.

    ERIC Educational Resources Information Center

    Kaminsky, Judith Allen, Ed.

    2001-01-01

    This document is comprised of four issues of a quarterly publication presenting information related to the Reggio Emilia approach to early childhood education. Regularly appearing features of the publication include a calendar of Reggio conferences; information on the Reggio Children organization, contacts, exhibit schedule, and study tours; and a…

  7. Live Supervision in Family Therapy: An Interview With Barbara Okun and Fred Piercy.

    ERIC Educational Resources Information Center

    West, John D.; And Others

    1989-01-01

    Describes special program on live supervision in family therapy given at 1988 annual American Association for Counseling and Development (AACD) Conference that featured experts Barbara Okun and Fred Piercy discussing "cotherapy" and "one-way mirror" live supervision approaches. Provides edited transcript of their program.…

  8. ASP Networking Sessions Summary

    NASA Astrophysics Data System (ADS)

    Bartolone, L. M.

    2008-06-01

    In response to evaluation conducted during the Annual Meeting of the Astronomical Society of the Pacific in 2006, ``Engaging the EPO Community: Best Practices, New Approaches,'' loosely structured networking sessions were added by the program committee in an effort to assist conference attendees in achieving their stated conference goals. The co-chairs of the 2007 conference invited registrants to serve as facilitators for twelve networking sessions. This work aims to summarize the conversations that took place during those sessions, based upon notes and artifacts provided to the author by the session facilitators.

  9. Mechanics of Textile Composites Conference. Part 1

    NASA Technical Reports Server (NTRS)

    Poe, Clarence C., Jr. (Editor); Harris, Charles E. (Editor)

    1995-01-01

    This document is a compilation of papers presented at the Mechanics of Textile Composites Conference in Hampton, Virginia, December 6-8, 1994. This conference was the culmination of a 3-year program that was initiated by NASA late in 1990 to develop mechanics of textile composites in support of the NASA Advanced Composites Technology Program (ACT). The goal of the program was to develop mathematical models of textile preform materials and test methods to facilitate structural analysis and design. Participants in the program were from NASA, academia, and industry.

  10. PREFACE: 1982 International Conference on Plasma Physics

    NASA Astrophysics Data System (ADS)

    Wilhelmsson, Hans

    1982-01-01

    Invited Papers: The Physics of Hot Plasmas During the last decade a dramatic evolution of plasma physics has occurred. Not only have gigantic fusion plasma machines been planned, and are now being built, and elaborate spaceships and antenna systems been constructed to explore remote parts of the cosmos; new observations have revealed fascinating structures in space, ranging from pulsar plasmas under extreme conditions in very strong magnetic fields to large-scale magnetic field and electric current systems in cosmic plasmas. X-rays from very distant sources as well as radio-waves from the plasma in the magnetosphere and in the Aurora have recently been studied with new observational techniques. Ingenious laboratory experiments are continuously being carried out to exploit new fundamental processes in plasmas. These are of great interest for the basic understanding of plasmas and also have immediate consequences for applications, like plasma heating and diagnostics. The theoretical description of new plasma phenomena, and of the plasma state in general poses challenging problems, particularly in situations where high concentration of energy is located in the plasmas. Nonlinear wave analysis and turbulence theory have accordingly been extensively developed to describe in particular the collective plasma phenomena. New concepts have been envisaged like plasma solitons, which may be thought of as excitations of local concentrations of longitudinal plasma waves which turn out to be particularly stable. More and more sophisticated structures of nonlinear nature are being revealed by means of high capacity computer facilities. Simulation experiments allow for studies of chaotic behaviour of plasma particles. Related fields of activity form new trends in the development of plasma theory. The programme of the 1982 International Conference on Plasma Physics, which was held in Göteborg, Sweden, stressed the role of the Physics of Hot Plasmas. Studies of such plasmas are essential, not only for fusion energy development, but also for astro- and space research. Plasmas in different situations often have important features in common. Results obtained under various conditions, in the laboratory or in space, should therefore be compared and interrelated. The Göteborg conference emphasized more than the previous one, which was held in Nagoya, Japan, the astro- and space aspects, but there were still more contributions from the fusion and laboratory research. The fundamental plasma theory part was, however, the most extensive one in the programme. At the conference there were seventy invited talks, including six comprehensive talks addressed to all participants. The remaining sixtyfour invited talks were topical talks. Besides, we had received about 450 contributed papers. About 300 of them were given as posters, and most of the remaining ones were presented as orals. The set of one page abstracts of these contributed papers as well as the titles of the invited talks were collected in two volumes, which were sent to all participants a month before the conference. Another set, the four page papers, which had been carefully prepared by the authors for photoreproduction to one page papers, were published in a volume of proceedings of some 460 pages available at the conference. When trying to classify the contributions, it turned out that they fell naturally into four main categories, namely: General Theory Space and Astro Plasmas Fusion Laboratory Plasmas For practical reasons we had to divide the Abstracts into two Volumes, the first one including categories (1) and (2), and the second one the two remaining categories (3) and (4). In publishing the invited talks from the conference we had to handle a great number of extensive papers. It turned out to be natural to have also the invited papers published in two parts, as two separate numbers of Physica Scripta, the first one devoted to (1) General Theory, and (2) Space and Astro Plasmas, whereas the second one to (3) Fusion and (4) Laboratory Plasmas. The 1982 International Conference on Plasma Physics was organized by Chalmers University of Technology. It gathered about 500 participants from 40 countries. Large delegations came from the USA, France, West Germany, Japan, the USSR, and India, the number of participants from these countries ranging from 100 to 20. Sweden had about 50 participating scientists. There were a total of about 20 from the other Scandinavian countries. The principal sponsor of the conference was IUPAP, the International Union of Pure and Applied Physics. The conference also had a number of co-sponsors like IAU, the International Astronomical Union, URSI, the International Union of Radio Science, EPS, the European Physical Society, and EURATOM-FUSION. The conference was supported by Swedish Industry and Swedish Research Boards. The previous ICPP, held in Nagoya two years ago, was the first attempt to combine two types of conferences: the Plasma Theory Conference, first held in Kiev in the Soviet Union in 1971, and the Waves and Instabilities Congress, held for the first time in Innsbruck, Austria in 1973. As a consequence of the success of the Nagoya conference it was decided by the International Organizing Committee of the ICPP that the 1982 conference should also be of the combined type. The 1982 ICPP in Göteborg was thus a Joint Conference of the Fifth Kiev International Conference in Plasma Theory and the Fifth International Congress on Waves and Instabilities in Plasmas. During the conference in Göteborg the International Organizing Committee had a meeting and it was decided that also the next International Conference on Plasma Physics will be of the combined type. It will be held in Lausanne, Switzerland in 1984. The International Organizing Committee on the 1982 International Conference on Plasma Physics comprised about 40 plasma physics scientists from all over the world, who represented various sections of plasma physics. I would like to thank the active members of the IOC for an efficient and friendly co-operation in deciding about the program of invited speakers and for discussions on the general structure of the conference. Our most cordial thanks are extended to the invited speakers for coming to the conference to deliver such excellent talks and to provide us in good time for printing with so beautifully prepared manuscripts. Symposium on Plasma Theory: Preface Several satellite meetings were arranged following the 1982 International Conference on Plasma Physics in Göteborg. Among them a Symposium on Plasma Theory was held at Aspenäsgården outside Göteborg during three days, June 16-18, 1982. The purpose of the symposium was to discuss problems of current interest in plasma theory with applications to space and astrophysical plasmas as well as to fusion plasmas. A total of fifteen talks were given during the three days, and some very lively discussions arose, notably in the area of plasma turbulence. There were around 30 invited scientists present, about one third from the United States, one third from the Soviet Union, and the rest from England, Japan, and various other countries. This volume of Physica Scripta (2B, 506-595) includes some of the talks which were given at Aspenäsgården. Several of the authors of contributed papers to the 1982 International Conference on Plasma Physics were encouraged to write extended versions of their contributions, and these are also included in this number, as are furthermore some papers, which were prepared during prolonged stays of visiting scientists at our institute in connection with the 1982 ICPP. It is expected that the collection of papers thus assembled will give a general picture of the activities accompanying the main conference and that it will elucidate some trends in the development of plasma theory.

  11. Adaptive and active materials: selected papers from the ASME 2013 Conference on Smart Materials, Adaptive Structures and Intelligent Systems (SMASIS 13) (Snowbird, UT, USA, 16-18 September 2013)

    NASA Astrophysics Data System (ADS)

    Johnson, Nancy; Naguib, Hani; Turner, Travis; Anderson, Iain; Bassiri-Gharb, Nazanin; Daqaq, Mohammed; Baba Sundaresan, Vishnu; Sarles, Andy

    2014-10-01

    The sixth annual meeting of the ASME Smart Materials, Adaptive Structures and Intelligent Systems Conference (SMASIS) was held in the beautiful mountain encircled Snowbird Resort and Conference Center in Little Cottonwood Canyon near Salt Lake City, Utah. It is the conference's objective to provide an up-to-date overview of research trends in the entire field of smart materials systems in a friendly casual forum conducive to the exchange of ideas and latest results. As each year we strive to grow and offer new experiences, this year we included special focused topic tracks on nanoscale multiferroic materials and origami engineering. The cross-disciplinary emphasis was reflected in keynote speeches by Professor Kaushik Bhattacharya (California Institute of Technology) on 'Cyclic Deformation and the Interplay between Phase Transformation and Plasticity in Shape Memory Alloys', by Professor Alison Flatau (University of Maryland at College Park) on 'Structural Magnetostrictive Alloys: The Other Smart Material', and by Dr Leslie Momoda (Director of the Sensors and Materials Laboratories, HRL Laboratories, LLC, Malibu, CA) on 'Architecturing New Functional Materials: An Industrial Perspective'. SMASIS 2013 was divided into seven symposia which span basic research, applied technological design and development, and industrial and governmental integrated system and application demonstrations. SYMP 1. Development and Characterization of Multifunctional Materials. SYMP 2. Mechanics and Behavior of Active Materials. SYMP 3. Modeling, Simulation and Control of Adaptive Systems. SYMP 4. Integrated System Design and Implementation. SYMP 5. Structural Health Monitoring. SYMP 6. Bioinspired Smart Materials and Systems. SYMP 7. Energy Harvesting. Authors of selected papers in the materials areas (symposia 1, 2, and 6) as well as energy harvesting (symposium 7) were invited to write a full journal article on their presentation topic for publication in this special issue of Smart Materials and Structures. This collection of papers demonstrates the exceptional quality and originality of the conference presentations. We are very appreciative of their efforts to produce this collection of highly relevant articles on smart materials.

  12. PREFACE: Physics and Mathematics of Nonlinear Phenomena 2013 (PMNP2013)

    NASA Astrophysics Data System (ADS)

    Konopelchenko, B. G.; Landolfi, G.; Martina, L.; Vitolo, R.

    2014-03-01

    Modern theory of nonlinear integrable equations is nowdays an important and effective tool of study for numerous nonlinear phenomena in various branches of physics from hydrodynamics and optics to quantum filed theory and gravity. It includes the study of nonlinear partial differential and discrete equations, regular and singular behaviour of their solutions, Hamitonian and bi- Hamitonian structures, their symmetries, associated deformations of algebraic and geometrical structures with applications to various models in physics and mathematics. The PMNP 2013 conference focused on recent advances and developments in Continuous and discrete, classical and quantum integrable systems Hamiltonian, critical and geometric structures of nonlinear integrable equations Integrable systems in quantum field theory and matrix models Models of nonlinear phenomena in physics Applications of nonlinear integrable systems in physics The Scientific Committee of the conference was formed by Francesco Calogero (University of Rome `La Sapienza', Italy) Boris A Dubrovin (SISSA, Italy) Yuji Kodama (Ohio State University, USA) Franco Magri (University of Milan `Bicocca', Italy) Vladimir E Zakharov (University of Arizona, USA, and Landau Institute for Theoretical Physics, Russia) The Organizing Committee: Boris G Konopelchenko, Giulio Landolfi, Luigi Martina, Department of Mathematics and Physics `E De Giorgi' and the Istituto Nazionale di Fisica Nucleare, and Raffaele Vitolo, Department of Mathematics and Physics `E De Giorgi'. A list of sponsors, speakers, talks, participants and the conference photograph are given in the PDF. Conference photograph

  13. Employer Policies and Practices to Manage and Prevent Disability: Conclusion to the Special Issue.

    PubMed

    Main, Chris J; Shaw, William S

    2016-12-01

    Purpose Research of employer policies and practices to manage and prevent disability spans many disciplines and perspectives, and there are many challenges related to stakeholder collaboration, data access, and interventions. The purpose of this article is to synthesize the findings from a conference and year-long collaboration among a group of invited researchers intended to spur new research innovations in this field. Methods A multidisciplinary team of 26 international researchers with published research in employer-based disability management or related fields were invited to attend a 3-day conference in Hopkinton, Massachusetts, USA. The conference goals were to review the status of current research of workplace disability management and prevention, examine its relevance for employer decision-making, compare conceptual frameworks or theoretical perspectives, and recommend future research directions. In this paper, we summarize key points from the 6 resulting papers, compare them with an earlier 2005 conference on improving return-to-work research, and conclude with recommendations for further overarching research directions. Results/Conclusion In comparison with the 2005 conference, a greater emphasis was placed on organizational and social factors, employer roles and responsibilities, methods of implementation, non-clinical approaches, and facilitating stay-at-work as well as return-to-work. A special panel of employer consultants and representatives who were featured at the 2015 conference reinforced the importance of organizational culture, leadership style, and financial decision-making strategies at the employer level. Based on the conference proceedings, we recommend that future research in this area should strive for: (a) broader inclusion of workers and workplaces; (b) attention to multilevel influences in the workplace; (c) a focus on social as well as physical aspects of work; (d) earlier employer collaboration efforts; (e) more attention to implementation factors; and (f) a broader assessment of possible outcome domains.

  14. FOREWORD: Nuclear Physics in Astrophysics V

    NASA Astrophysics Data System (ADS)

    Auerbach, Naftali; Hass, Michael; Paul, Michael

    2012-02-01

    The fifth edition of the bi-annual 'Nuclear Physics in Astrophysics (NPA)' conference series was held in Eilat, Israel on April 3-8, 2011. This Conference is also designated as the 24th Nuclear Physics Divisional Conference of the EPS. The main purpose of this conference, as that of the four previous ones in this series, is to deal with those aspects of nuclear physics that are directly related to astrophysics. The concept of such a meeting was conceived by the Nuclear Physics Board of the European Physical Society in 1998. At that time, the idea of such a conference was quite new and it was decided that this meeting would be sponsored by the EPS. The first meeting, in January 2001, was planned and organized in Eilat, Israel. Due to international circumstances the conference was moved to Debrecen, Hungary. Subsequent conferences were held in Debrecen again, in Dresden, Germany, and in Frascati, Italy (moved from Gran Sasso due to the tragic earthquake that hit the L'Aquila region). After 10 years the conference finally returned to Eilat, the originally envisioned site. Eilat is a resort town located on the shore of the Gulf of Eilat, which connects Israel to the Red Sea and further south to the Indian Ocean. It commands spectacular views of the desert and mountains, offering unique touristic attractions. The local scientific backdrop of the conference is the fact that the Israeli scientific scene exhibits a wide variety of research activities in many areas of nuclear physics and astrophysics. A new accelerator, SARAF at Soreq Nuclear Research Center is presently undergoing final acceptance tests. SARAF will serve as a platform for production of radioactive ion beams and nuclear-astrophysics research in Israel. The meeting in Eilat was organized by four Israeli scientific institutions, Hebrew University, Soreq Nuclear Research Center, Tel Aviv University and the Weizmann Institute of Science. The welcome reception and lectures were held at the King Solomon hotel and the conference dinner banquet at the Dan hotel. An excursion to the 'Red Canyon' in the Eilat Mountains on Wednesday afternoon was one of the social highlights of the conference. A total number of 140 scientists attended NPA5 and about 30 accompanying persons; about 25% of these were young participants (less than 36 years old). 23 participants were from Israel, and 27 were from outside of Europe (including two from Africa). The subjects covered at the conference in Eilat concentrated mainly on the spirit of the original idea - to probe experimental and theoretical activity in nuclear structure and reactions that is directly related to the physics of the Universe. There were also sessions of general interest in astrophysics, as well as a poster session on Tuesday evening featuring 40 posters. The topics included: Nuclear Structure - Theory and Experiment Big-Bang Nucleosynthesis and Formation of First Stars Stellar Reactions and Solar Neutrinos Explosive Nucleosynthesis, Radioactive Beams and Exotic Nuclei-New Facilities and Future Possibilities for Astrophysics Neutrino Physics - the Low and High-Energy Frontiers Rare events, Dark Matter, Double beta-decay, Symmetries The conference started with an excellent exposé of the progress made in the discovery of super-heavy elements and the study of their properties. The progress in this field is enormous, and this subject should be communicated to more general audiences. The role of the nuclear equation of state and of the precise determination of nuclear masses in nucleosynthesis was emphasized in several talks. The role of neutrinos in astrophysics was discussed extensively in several sessions. One of the highlights of this was the presentation about the IceCube and DeepCore detectors operating deep in the Antarctic ice. These facilities are able to detect cosmogenic neutrinos in a wide energy range, from 10 GeV to 1010 GeV. The subject of solar neutrinos was discussed in a number of talks. Topics related to properties of neutrinos, such as double-beta decay and neutrino mixing were well represented at the conference. One of the central problems in modern cosmology and astrophysics is the search for dark matter. Several talks dealt with this subject and with methods to detect dark matter. Another intriguing and rather novel subject that was discussed at the meeting was time variation of fundamental physical constants. Two speakers have examined the sensitivity of Big-Bang Nucleosynthesis to the variation of the values of the fundamental constants. The role of some specific nuclei (such as Ni 56) in cosmology was pointed out. Many of the presentations at the conference described experimental studies of reactions relevant to nucleosynthesis at various stages of cosmic evolution. As reflected in the conference, these activities are widespread, encompassing many laboratories. Rare Isotope Beam (RIB) facilities are in the forefront of these studies. To understand the various processes of nucleosynthesis one has to have a good theory of nuclei far from the stability line. A number of presentations dealt with the description of such exotic nuclei. It is clear from the presentations that the future of experimental nuclear astrophysics looks promising as existing experimental facilities are being upgraded and new facilities are being built. X-Ray and Gamma-Ray Bursts and cosmic explosions were the subject of several talks. A discussion of various experiments attempting to measure time-reversal violation was the subject of one lecture. The solution of the puzzle as to why the universe is asymmetric with respect to matter-antimatter requires knowledge of the limit of time-reversal conservation. The late John Bahcall was a great astrophysicist and a supporter of the conference series 'Nuclear physics in Astrophysics'. On the last day of the conference, following a talk by Neta Bahcall from Princeton University on dark matter in the Universe, a short commemoration for John was held. Detailed information about the NPA5 conference and its scientific program can be found at: www.weizmann.ac.il/conferences/NPA5/ Naftali Auerbach Michael Hass Michael Paul Editors Conference photograph Conference photograph The PDF also contains lists of the committees and participants.

  15. Families: An Expanding Role for Professional Counselors. Proceedings of the Conference (San Antonio, Texas, February 1-3, 1986).

    ERIC Educational Resources Information Center

    Cohen, George M.; And Others

    This document contains papers from a conference which targeted the needs and interests of counselors working with families. Individual papers in the book include: (1) "Economic, Social and Political Influences on Families" (Lynda Henley Walters); (2) "Family Structures and Stresses: A Counseling Perspective" (Edwin Herr); (3) "Cultural Diversity…

  16. Preface

    NASA Astrophysics Data System (ADS)

    De Hosson, Jeff Th. M.; Ali, Nasar; Fierro, Giuseppe; Aliofkhazraei, Mahmood; Chipara, Mircea

    2016-09-01

    The ;International Conference on Surfaces, Coatings and Nano-Structured Materials; (NANOSMAT) has rapidly emerged as the premier conference in the field of materials science, engineering, technology and all aspects of ;nano;. Since 2005, it has been very successfully organised in several European countries, including Portugal, Spain, Italy, France, Poland, Czech Republic, Ireland and also in USA, and in Asia, including Turkey and China.

  17. Renewing and Developing the Partnership: Federal/State/Campus Cooperation in Student Financial Aid.

    ERIC Educational Resources Information Center

    Fenske, Robert H., Ed.; Clark, Patricia L., Ed.

    The proceedings of the conference are summarized, including a symposium discussion following the formal conference. Contents include: two views of the present advisory structure for student aid (The Case for Maintaining and Expanding the Coalition for the Coordination of Student Financial Aid, by Robert H. Atwell, and The Need for Developing a…

  18. Research into Higher Education: Processes and Structures. Information on Higher Education in Sweden.

    ERIC Educational Resources Information Center

    National Swedish Board of Universities and Colleges, Stockholm. Research and Development Unit.

    Taken from an international conference organized by the Swedish National Board of Universities and Colleges, the report consists of six overview papers, five reports from discussion groups, and a transcript of the concluding discussion. The conference was designed to allow an informal exchange between researchers and practitioners in the field of…

  19. Changing Work Force Needs with Implications for Higher Education. Proceedings of the Wingspread Conference (Racine, Wisconsin, October 23-24, 1978).

    ERIC Educational Resources Information Center

    Johnson Foundation, Inc., Racine, WI.

    Four conference presentations analyze changing workforce needs and consider their implications for higher education. Richard Hey presents an overview of trends in lifestyles in the United States, discussing the changing roles of women, new structures of primary relationships, mid-life career change, increased lifespan, and attitudes toward…

  20. Preface

    NASA Astrophysics Data System (ADS)

    De Hosson, Jeff Th. M.; Ali, Nasar; Fierro, Giuseppe; Aliofkhazraei, Mahmood; Chipara, Mircea

    2017-11-01

    The ;International Conference on Surfaces, Coatings and Nano-Structured Materials; (NANOSMAT) has rapidly emerged as the premier conference in the field of materials science, engineering, technology and all aspects of ;nano;. Since 2005, it has been very successfully organised in several European countries, including Portugal, Spain, Italy, France, Poland, Czech Republic, Ireland, United Kingdom and also in USA, and in Asia, including Turkey and China.

  1. BCR-ABL1 Compound Mutations Combining Key Kinase Domain Positions Confer Clinical Resistance to Ponatinib in Ph Chromosome-Positive Leukemia

    PubMed Central

    Zabriskie, Matthew S.; Eide, Christopher A.; Tantravahi, Srinivas K.; Vellore, Nadeem A.; Estrada, Johanna; Nicolini, Franck E.; Khoury, Hanna J.; Larson, Richard A.; Konopleva, Marina; Cortes, Jorge E.; Kantarjian, Hagop; Jabbour, Elias J.; Kornblau, Steven M.; Lipton, Jeffrey H.; Rea, Delphine; Stenke, Leif; Barbany, Gisela; Lange, Thoralf; Hernández-Boluda, Juan-Carlos; Ossenkoppele, Gert J.; Press, Richard D.; Chuah, Charles; Goldberg, Stuart L.; Wetzler, Meir; Mahon, Francois-Xavier; Etienne, Gabriel; Baccarani, Michele; Soverini, Simona; Rosti, Gianantonio; Rousselot, Philippe; Friedman, Ran; Deininger, Marie; Reynolds, Kimberly R.; Heaton, William L.; Eiring, Anna M.; Pomicter, Anthony D.; Khorashad, Jamshid S.; Kelley, Todd W.; Baron, Riccardo; Druker, Brian J.; Deininger, Michael W.; O'Hare, Thomas

    2014-01-01

    Summary Ponatinib is the only currently approved tyrosine kinase inhibitor (TKI) that suppresses all BCR-ABL1 single mutants in Philadelphia chromosome-positive (Ph+) leukemia, including the recalcitrant BCR-ABL1T315I mutant. However, emergence of compound mutations in a BCR-ABL1 allele may confer ponatinib resistance. We found that clinically reported BCR-ABL1 compound mutants center on 12 key positions and confer varying resistance to imatinib, nilotinib, dasatinib, ponatinib, rebastinib and bosutinib. T315I-inclusive compound mutants confer high-level resistance to TKIs, including ponatinib. In vitro resistance profiling was predictive of treatment outcomes in Ph+ leukemia patients. Structural explanations for compound mutation-based resistance were obtained through molecular dynamics simulations. Our findings demonstrate that BCR-ABL1 compound mutants confer different levels of TKI resistance, necessitating rational treatment selection to optimize clinical outcome. PMID:25132497

  2. Summary of talks and papers at ISCB-Asia/SCCG 2012

    PubMed Central

    2013-01-01

    The second ISCB-Asia conference of the International Society for Computational Biology took place December 17-19, 2012, in Shenzhen, China. The conference was co-hosted by BGI as the first Shenzhen Conference on Computational Genomics (SCCG). 45 talks were presented at ISCB-Asia/SCCG 2012. The topics covered included software tools, reproducible computing, next-generation sequencing data analysis, transcription and mRNA regulation, protein structure and function, cancer genomics and personalized medicine. Nine of the proceedings track talks are included as full papers in this supplement. In this report we first give a short overview of the conference by listing some statistics and visualizing the talk abstracts as word clouds. Then we group the talks by topic and briefly summarize each one, providing references to related publications whenever possible. Finally, we close with a few comments on the success of this conference.

  3. 10. international mouse genome conference

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Meisler, M.H.

    Ten years after hosting the First International Mammalian Genome Conference in Paris in 1986, Dr. Jean-Louis Guenet presided over the Tenth Conference at the Pasteur Institute, October 7--10, 1996. The 1986 conference was a satellite to the Human Gene Mapping Workshop and had approximately 50 attendees. The 1996 meeting was attended by 300 scientists from around the world. In the interim, the number of mapped loci in the mouse increased from 1,000 to over 20,000. This report contains a listing of the program and its participants, and two articles that review the meeting and the role of the laboratory mousemore » in the Human Genome project. More than 200 papers were presented at the conference covering the following topics: International mouse chromosome committee meetings; Mutant generation and identification; Physical and genetic maps; New technology and resources; Chromatin structure and gene regulation; Rate and hamster genetic maps; Informatics and databases; and Quantitative trait analysis.« less

  4. CHAIRMEN'S FOREWORD: The Seventh International Conference on New Phenomena in Mesoscopic Structures & The Fifth International Conference on Surfaces and Interfaces of Mesoscopic Devices

    NASA Astrophysics Data System (ADS)

    Aoyagi, Yoshinobu; Goodnick, Stephen M.

    2006-05-01

    This special issue of the Journal of Physics: Conference Series contains the proceedings of the joint Seventh International Conference on New Phenomena in Mesoscopic Structures and Fifth International Conference on Surfaces and Interfaces of Mesoscopic Devices, which was held from November 27th - December 2nd, 2005, at the Ritz Carlton Kapalua, Maui, Hawaii. The string of these conferences dates back to the first one in 1989. Of special importance is that this year's conference was dedicated to Professor Gottfried Landwehr, in recognition of his many outstanding contributions to semiconductor physics. A personal tribute to Prof Landwehr by Dr K von Klitzing leads off this issue. The scope of NPMS-7/SIMD-5 spans nano-fabrication through complex phase coherent mesoscopic systems including nano-transistors and nano-scale characterization. Topics of interest include: •Nanoscale fabrication: high-resolution electron lithography, FIB nano-patterning, scanning- force-microscopy (SFM) lithography, SFM-stimulated growth, novel patterning, nano-imprint lithography, special etching, and self-assembled monolayers •Nanocharacterization: SFM characterization, ballistic-electron emission microscopy (BEEM), optical studies of nanostructures, tunneling, properties of discrete impurities, phase coherence, noise, THz studies, and electro-luminescence in small structures •Nanodevices: ultra-scaled FETs, quantum single-electron transistors (SETS), resonant tunneling diodes, ferromagnetic and spin devices, superlattice arrays, IR detectors with quantum dots and wires, quantum point contacts, non-equilibrium transport, simulation, ballistic transport, molecular electronic devices, carbon nanotubes, spin selection devices, spin-coupled quantum dots, and nanomagnetics •Quantum-coherent transport: the quantum Hall effect, ballistic quantum systems, quantum-computing implementations and theory, and magnetic spin systems •Mesoscopic structures: quantum wires and dots, quantum chaos, non-equilibrium transport, instabilities, nano-electro-mechanical systems, mesoscopic Josephson effects, phase coherence and breaking, and the Kondo effect •Systems of nanodevices: Quantum cellular automata, systolic SET processors, quantum neural nets, adaptive effects in circuits, and molecular circuits •Nanomaterials: nanotubes, nanowires, organic and molecular materials, self-assembled nano wires, and organic devices •Nanobioelectronics: electronic properties of biological structures on the nanoscale. This year's conference was organized by Prof Stephen Goodnick, Arizona State University, and Prof Yoshinobu Aoyagi, Tokyo Institute of Technology. The conference benefited from 14 invited speakers, whose topics spanned the above list, and a total of 97 registered attendees. The largest contingent was from Japan, followed closely by the US. In total, there were 49 from Japan, 31 fiom the US, and 17 from Europe. The organizers want to especially thank the sponsors for the meeting: The Office of Naval Research, the Army Research Office, and Arizona State University on the US side, and the Japan Society for the Promotion of Science, through their 151 Committee, on the Japanese side. PROGRAM COMMITTEE •Prof Gerhard Abstreiter, Technical University of Munich •Prof Tsuneya Ando, Tokyo Institute of Technology •Prof John Barker, University of Glasgow •Prof Jonathan Bird, the University at Buffalo •Prof Robert Blick, University of Wisconsin •Prof David Ferry, Chair, Arizona State University •Dr Yoshiro Hirayama, NTT Basic Research Laboratories •Dr Koji Ishibashi, RIKEN •Prof Carlo Jacoboni, University of Modena •Prof David Janes, Purdue University •Prof Friedl Kuchar, University of Leoben •Prof K. Matsumoto, Osaka University •Prof Wolfgang Porod, Notre Dame University •Prof Michiharu Tabe, Shizuoka University •Prof Joachim Wolter, Eindhoven Institute of Technology •Prof Lukas Worschech, University of Würzburg •Dr Naoki Yokoyama, Fujitsu Research

  5. 32nd International Conference on the Physics of Semiconductors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chelikowsky, James

    The International Conference on the Physics of Semiconductors (ICPS) continues a series of biennial conferences that began in the 1950's. ICPS is the premier meeting for reporting all aspects of semiconductor physics including electronic, structural, optical, magnetic and transport properties with an emphasis on new materials and their applications. The meeting will reflect the state of art in the semiconductor physics field and will serve as a forum where scholars, researchers, and specialists can interact to discuss future research directions and technological advancements. The conference typically draws 1,000 international physicists, scientists, and students. This is one of the largest sciencemore » meetings on semiconductors and related materials to be held in the United States.« less

  6. The Global Precipitation Patterns Associated with Short-Term Extratropical Climate Fluctuations

    NASA Technical Reports Server (NTRS)

    Huffman, George J.; Adler, Robert F.; Bolvin, David T.

    1999-01-01

    Two globally-complete, observation-only precipitation datasets have recently been developed for the Global Precipitation Climatology Project (GPCP). Both depend heavily on a variety of satellite input, as well as gauge data over land. The first, Version 2x79, provides monthly estimates on a 2.5 deg. x 2.5 deg. lat/long grid for the period 1979 through late 1999 (by the time of the conference). The second, the One-Degree Daily (1DD), provides daily estimates on a 1 deg. x l deg. grid for the period 1997 through late 1999 (by the time of the conference). Both are in beta test preparatory to release as official GPCP products. These datasets provide a unique perspective on the hydrological effects of the various atmospheric flow anomalies that have been identified by meteorologists. In this paper we discuss the regional precipitation effects that result from persistent extratropical flow anomalies. We will focus on the Pacific-North America (PNA) and North Atlantic Oscillation (NAO) patterns. Each characteristically becomes established on synoptic time scales, but then persists for periods that can exceed a month. The onset phase of each appears to have systematic mobile features, while the mature phase tend to be more stationary. Accordingly, composites of monthly data for outstanding positive and negative events (separately) contained in the 20-year record reveal the climatological structure of the precipitation during the mature phase. The climatological anomalies of the positive, negative, and (positive-negative) composites show the expected storm-track-related shifts in precipitation, and provide the advantage of putting the known precipitation effects over land in the context of the total pattern over land and ocean. As well, this global perspective points out some unexpected areas of correlation. Day-by-day composites of daily data anchored to the onset date demonstrate the systematic features during the onset. Although the 1DD has a fairly short record, some preliminary results are shown and compared to previous work with numerical weather prediction models.

  7. A Global Precipitation Perspective on Persistent Extratropical Flow Anomalies

    NASA Technical Reports Server (NTRS)

    Huffman, George J.; Adler, Robert F.; Bolvin, David T.

    1999-01-01

    Two globally-complete, observation-only precipitation datasets have recently been developed for the Global Precipitation Climatology Project (GPCP). Both depend heavily on a variety of satellite input, as well as gauge data over land. The first, Version 2 x 79, provides monthly estimates on a 2.5 deg x 2.5 deg lat/long grid for the period 1979 through late 1999 (by the time of the conference). The second, the One-Degree Daily (1DD), provides daily estimates on a 1 deg x 1 deg grid for the period 1997 through late 1999 (by the time of the conference). Both are in beta test preparatory to release as official GPCP products. These datasets provide a unique perspective on the hydrological effects of the various atmospheric flow anomalies that have been identified by meteorologists. In this paper we discuss the regional precipitation effects that result from persistent extratropical flow anomalies. We will focus on the Pacific-North America (PNA) and North Atlantic Oscillation (NAO) patterns. Each characteristically becomes established on synoptic time scales, but then persists for periods that can exceed a month. The onset phase of each appears to have systematic mobile features, while the mature phase tend to be more stationary. Accordingly, composites of monthly data for outstanding positive and negative events (separately) contained in the 20-year record reveal the climatological structure of the precipitation during the mature phase. The climatological anomalies of the positive, negative, and (positive-negative) composites show the expected storm-track-related shifts in precipitation, and provide the advantage of putting the known precipitation effects over land in the context of the total pattern over land and ocean. As well, this global perspective points out some unexpected areas of correlation. Day-by-day composites of daily data anchored to the onset date demonstrate the systematic features during the onset. Although the 1DD has a fairly short record, some preliminary results are shown and compared to previous work with numerical weather prediction models.

  8. Defining Value in Cancer Care: AVBCC 2012 Steering Committee Report

    PubMed Central

    Beed, Gene; Owens, Gary M.; Benson, Al B.; Klein, Ira M.; Silver, Samuel M.; Beveridge, Roy A.; Malin, Jennifer; Sprandio, John D.; Deligdish, Craig K.; Mitchell, Matthew; Vogenberg, F. Randy; Fox, John; Newcomer, Lee N.

    2012-01-01

    Approximately 200 oncologists, payers, employers, managed care executives, pharmacy benefit managers, and other healthcare stakeholders convened in Houston, TX, on March 28–31, 2012, for the Second Annual Conference of the Association for Value-Based Cancer Care (AVBCC). The mission of the conference was to align the various perspectives around the growing need of defining value in cancer care and developing strategies to enhance patient outcomes. The AVBCC conference presented a forum for the various viewpoints from all the stakeholders across the cancer care continuum, featuring more than 20 sessions and symposia led by nearly 30 oncology leaders. The discussions focused on current trends and challenges in optimizing value in oncology by reducing or controlling cost while improving care quality and patient outcomes, introducing emerging approaches to management and tools that providers and payers are using to enhance cancer care collaboratively. The AVBCC Second Annual Conference was opened by a Steering Committee discussion of 11 panel members who attempted to define value in cancer care and articulated action steps that can help to implement value into cancer care delivery. The following summary represents highlights from the Steering Committee discussion, which was moderated by Gene Beed, MD, and Gary M. Owens, MD. PMID:24991320

  9. Defining Value in Cancer Care: AVBCC 2012 Steering Committee Report.

    PubMed

    Beed, Gene; Owens, Gary M; Benson, Al B; Klein, Ira M; Silver, Samuel M; Beveridge, Roy A; Malin, Jennifer; Sprandio, John D; Deligdish, Craig K; Mitchell, Matthew; Vogenberg, F Randy; Fox, John; Newcomer, Lee N

    2012-07-01

    Approximately 200 oncologists, payers, employers, managed care executives, pharmacy benefit managers, and other healthcare stakeholders convened in Houston, TX, on March 28-31, 2012, for the Second Annual Conference of the Association for Value-Based Cancer Care (AVBCC). The mission of the conference was to align the various perspectives around the growing need of defining value in cancer care and developing strategies to enhance patient outcomes. The AVBCC conference presented a forum for the various viewpoints from all the stakeholders across the cancer care continuum, featuring more than 20 sessions and symposia led by nearly 30 oncology leaders. The discussions focused on current trends and challenges in optimizing value in oncology by reducing or controlling cost while improving care quality and patient outcomes, introducing emerging approaches to management and tools that providers and payers are using to enhance cancer care collaboratively. The AVBCC Second Annual Conference was opened by a Steering Committee discussion of 11 panel members who attempted to define value in cancer care and articulated action steps that can help to implement value into cancer care delivery. The following summary represents highlights from the Steering Committee discussion, which was moderated by Gene Beed, MD, and Gary M. Owens, MD.

  10. Mitochondria in health and disease - 3rd annual conference of society for mitochondrial research and medicine - 19-20 December 2013 - Bengaluru, India.

    PubMed

    Durhuus, Jon Ambæk; Desler, Claus; Rasmussen, Lene Juel

    2015-01-01

    The primary role of mitochondria was long considered to be production of cellular energy. However, as the understanding of mitochondria in disease is ever expanding, so is their additional function for a healthy organism. Mitochondrial dysfunction is linked to a range of pathologies, including cancer, neurodegenerative disorders, premature aging, diabetes and muscular diseases. Mitochondrial diseases can be hard to diagnose and treat and, therefore, interdisciplinary research and communication are important. The Third Annual Conference of Society for Mitochondrial Research and Medicine - India (SMRM) was titled "Mitochondria in Health and Disease". The conference was organized by Gayathri N, K Thangaraj, and KK Singh and was held at the National Institute of Mental Health & Neuro Sciences (NIMHANS) in Bangalore, India, from the 19th to 20th of December 2013. The meeting featured internationally renowned speakers within the field of mitochondrial research and medicine with the goal of bridging the gap between basic and clinical researchers. This review summarizes key outcomes of the conference. Copyright © 2014 © Elsevier B.V. and Mitochondria Research Society. Published by Elsevier B.V. All rights reserved.

  11. PREFACE: Proceedings of the International Conference on Optical, Optoelectronic and Photonic Materials and Applications (ICOOPMA) 2014

    NASA Astrophysics Data System (ADS)

    Sweeney, Stephen J.; Jha, Animesh

    2015-06-01

    Developments in the connected fields of optics, optoelectronics and photonics have had a profound effect on the emergence of modern technologies and their influence on our lives. In all of these fields, understanding and improving the basic underlying materials is of crucial importance for the development of systems and applications. The International Conference on Optical, Optoelectronic and Photonic Materials and Applications (ICOOPMA) has successfully married these fields and become a regular feature in the conference calendar. The 6th conference in the series, held at the University of Leeds from 27th July - 1st August, 2014, continued the ICOOPMA tradition and attracted 220 international delegates with a diverse range of disciplines and interests. The 59 papers in this Proceedings provide an excellent overview of the topics presented. The conference consisted of four thematic areas in the fields of inorganic semiconductors, carbon and polymeric materials, inorganic glasses and crystalline materials, and metamaterials and plasmonics where each theme area included research on basic materials through to device applications. The conference began with a Workshop organised by Professor Dan Hewak (University of Southampton) with speakers covering Organic Optoelectronic Complexes (Dr Richard Curry, University of Surrey), Metamaterials (Dr Vassili Fedotov, University of Southampton), Graphene (Dr Monica Craciun, University of Exeter) and Amorphous Semiconductors (Dr Jiri Orava, University of Cambridge and Tohoku University). This provided an excellent overview of a representative range of the important topics that were discussed further at the conference. The conference included a banquet which successfully combined excellent food with a relaxing opportunity for the conference delegates to socialise and network. The pinnacle of the evening was the after dinner speech given by our distinguished guest, Professor Sir David Payne (University of Southampton), who gave a highly informative and humorous history of the development of photonics and the important role played by optical fibres, of which he was one of the key pioneers. Emerging scientific talent was also given a platform, with a particular feature of the conference being the Young Scientists Forum, organised by Dr Senthil Ganapathy (University of Southampton), consisting of a series of themed sessions providing up-and-coming researchers a opportunity to present and discuss their work. Each technical theme of the conference was introduced with Plenary lectures delivered by leading international figures in their respective fields. Professor Jim Harris (Stanford University) discussed the development of epitaxially grown dilute-nitride semiconductors and the important role that they play in high efficiency solar cells. This theme was continued by Professor Wolfgang Stolz (Philipps University, Marburg) who described the use of novel III-V semiconductors for the development of lasers on silicon. Dr Jerry Meyer (Naval Research Laboratories) and Dr Kumar Patel (Pranalytica) discussed the important field of mid-infrared devices highlighting the significant developments that have been made in inter-band cascade and quantum cascade based devices, respectively and which have wide-ranging applications in sensing. Professor Neil Greenham (University of Cambridge) discussed solution-based semiconductors based on conjugated polymers and nanocrystals offering low cost routes to the wide-scale deployment of photonics. Professor Ortwin Hess (Imperial College) gave an overview of the physics and fascinating technological potential of negative refractive index materials. Professor Stephen Elliott (University of Cambridge) discussed the optoelectronic properties of phase change materials for memories. These areas were expanded upon in over 70 invited talks from international speakers highlighting recent developments in each of these areas. Further detailed discussions were presented in many parallel Oral and Poster sessions. This Proceedings provides an exciting and wide-ranging discussion of the topics presented at ICOOPMA 2014. We are very grateful to the many people who helped with the organisation of the conference, with particular thanks to Alison Whiteley and her team who enabled the smooth running of the conference, Dr Senthil Ganapathy for his many and wide ranging contributions to the conference and finally Professor Safa Kasap for his wisdom, advice and strong support. The conference could not have happened without the commitment of the Local Organising Committee, who helped in many ways to assemble and run the conference, and for the International Programme, Advisory and Steering committees who guided the technical direction of the conference and assisted with the conference programme and proceedings. We are also extremely pleased to have received generous sponsorship from a large number of organisations and companies. Finally, we are also very grateful to Sarah Toms and the Editorial staff at the Institute of Physics, and the many contributors and reviewers for helping us to put-together this proceedings. Stephen Sweeney, Guildford, UK Animesh Jha, Leeds, UK

  12. PREFACE: Euro-TMCS I: Theory, Modelling and Computational Methods for Semiconductors

    NASA Astrophysics Data System (ADS)

    Gómez-Campos, F. M.; Rodríguez-Bolívar, S.; Tomić, S.

    2015-05-01

    The present issue contains a selection of the best contributed works presented at the first Euro-TMCS conference (Theory, Modelling and Computational Methods for Semiconductors, European Session). The conference was held at Faculty of Sciences, Universidad de Granada, Spain on 28st-30st January 2015. This conference is the first European edition of the TMCS conference series which started in 2008 at the University of Manchester and has always been held in the United Kingdom. Four previous conferences have been previously carried out (Manchester 2008, York 2010, Leeds 2012 and Salford 2014). Euro-TMCS is run for three days; the first one devoted to giving invited tutorials, aimed particularly at students, on recent development of theoretical methods. On this occasion the session was focused on the presentation of widely-used computational methods for the modelling of physical processes in semiconductor materials. Freely available simulation software (SIESTA, Quantum Espresso and Yambo) as well as commercial software (TiberCad and MedeA) were presented in the conference by members of their development team, offering to the audience an overview of their capabilities for research. The second part of the conference showcased prestigious invited and contributed oral presentations, alongside poster sessions, in which direct discussion with authors was promoted. The scope of this conference embraces modelling, theory and the use of sophisticated computational tools in semiconductor science and technology. Theoretical approaches represented in this meeting included: Density Functional Theory, Semi-empirical Electronic Structure Methods, Multi-scale Approaches, Modelling of PV devices, Electron Transport, and Graphene. Topics included, but were not limited to: Optical Properties of Quantum Nanostructures including Colloids and Nanotubes, Plasmonics, Magnetic Semiconductors, Photonic Structures, and Electronic Devices. The Editors Acknowledgments: We would like to thank all participants for making this a very successful meeting and for their contribution to the conference programme and these proceedings. We would also like to acknowledge the financial support from Universidad de Granada, the CECAM UK-Hartree Node, project TEC2013-47283-R of Ministerio de Economía y Competitividad, and the company Materials Design (distributors of MedeA Software). Conference Organising Committee: Francisco M. Gómez-Campos (Co-chair, Universidad de Granada) Salvador Rodríguez-Bolívar (Co-chair, Universidad de Granada) Stanko Tomić (Co-chair, University of Salford)

  13. EDITORIAL: Special cluster on Dielectrics for Emerging Technologies

    NASA Astrophysics Data System (ADS)

    Clarke, R.; Youngs, I.; Stevens, G.

    2004-02-01

    The 2003 Conference on Dielectrics for Emerging Technologies was organised by the Institute of Physics Dielectrics Group as one of the participating conferences at the IOP Physics Congress held at Heriot-Watt University between 23 and 27 March 2003. This was the second annual conference of the new Dielectrics Group, which was formed from the former Dielectrics Society in October 2001. The conference policy remains unchanged, with the Group adopting an interdisciplinary and broadband approach to studies of the interaction of electromagnetic fields with materials. This policy is well exemplified by the papers that were delivered at this conference. The aims of the conference were three-fold: to provide a forum for the presentation of leading-edge research on emerging electromagnetic materials, to present developments on the use of dielectrics in emerging technologies and to broaden the debate on metamaterials in the UK, especially in relation to their potential applications. The metamaterials of interest here are macro- or meso-scopically structured materials that offer novel modes of electromagnetic field interaction, thereby widening the range of effective dielectric properties available to us for novel technological applications. They include `negative refractive index materials', `left handed materials', `photonic' or `electromagnetic band-gap materials' and actively-controlled or `smart' electromagnetic materials. Significant metamaterial applications are anticipated in the development of `perfect' lenses, filters, wavefront-conditioning layers and in improved metrology. The conference focussed additionally on dielectrics in support of electronics, photonics and optics, nano-materials, composites and structures, and the development of tuneable dielectrics and resonators for future applications in telecommunications. We are pleased to report that the conference was successful in achieving its objectives, thirty-four oral papers were delivered and twenty-three poster papers presented, many of which provoked significant debate. All contributions and the vigorous discussions held in this predominantly international forum testify to the health and vigour of this branch of materials physics and engineering. We were particularly pleased on this occasion to have the opportunity to run joint conference sessions with the `Structured Optical Materials' and `Electrostatics' conferences, which were run in parallel at the Congress. Electromagnetic materials science is inherently a cross-spectrum discipline and these sessions demonstrated the considerable overlap of technical interests and research from DC to optical frequencies. We are delighted to have the privilege of presenting eleven of the papers from the conference in this special cluster of Journal of Physics D: Applied Physics. Between them they capture the wide range of topics that were covered at the conference. The field of dielectric materials characterisation was well represented and amongst many other topics it included the study of nano-composites, represented here by the papers of Pelster et al and Hussain et al. Composite dielectrics at all scales lie at the centre of most new research into emerging applications and the paper by Bowler and that of Tuncer are also concerned with the understanding and characterisation of such materials. The understanding of the nature and distribution of space charge has always been a core dielectric study and a contribution to this field is made here by the paper of Marat-Mendes et al. Processing is a major factor that governs the properties of all dielectric materials---but this is particularly true in the case of sintered low-loss ceramics. The paper of Pullar et al adds to our knowledge in this important area. The remit of the conference led to the discussion of a very wide range of potential applications. One such is the use of dielectrophoretic forces for separating particles in suspensions (e.g. in pharmaceutical and diagnostic applications). The paper by Flores-Rodriguez and Markz presents a study on one aspect of this discipline. Presentations on meta- and structured materials at the conference are represented here in two papers: those of Shamonina and Solymar and of Zhou, Chan and Sheng, while a study in the closely allied area of band-gap materials is presented in the paper by Schuster and Klein. The final paper from the conference in this special cluster is concerned with an end-use application: the use of tuneable dielectric resonators in base-stations for future mobile telecoms networks. The paper by Krupka et al describes a magnetic approach to such tuning. In the longer term we sincerely hope that both the conference and these papers will prove to have made a significant contribution to the development and uses of dielectrics, and their metamaterial derivatives, in advanced technological applications. It is noteworthy that as a result of the success of this conference, the 2004 annual conference will be on the subject of `Dielectrics at Meso- and Nano-Scales'. We would like to take this opportunity to express our sincere thanks to all who participated in the conference for their contributions and we would like to express our particular thanks to the authors of the papers in this special cluster of Journal of Physics D: Applied Physics.

  14. Wisdom of the Crowds: Crowd-Based Development of a Logo for a Conference Using a Crowdsourcing Contest.

    PubMed

    Ong, Jason J; Bilardi, Jade E; Tucker, Joseph D

    2017-10-01

    Crowdsourcing methods have been widely used in business, but rarely in sexual health research. We evaluated a crowdsourced logo contest as part of an international human immunodeficiency virus conference. A logo crowdsourcing contest was conducted for the 20th International Acquired Immunodeficiency Syndrome Conference. Crowdsourcing has a group of individuals solve a task, often as part of an open contest. Semistructured interviews were conducted with key informants including contest organizers, contest contributors, and conference attendees. Interviews were transcribed verbatim and analysed using a content analysis approach. In total, 22 interviews were conducted with 3 contest organizers, 7 contest contributors, and 12 conference attendees. All individuals reported that the crowdsourced logo provided benefits beyond branding the conference, including creating a shared sense of purpose among diverse conference participants and explicitly demonstrating the strong community orientation of the conference. Conference organizers and attendees all reported deeper engagement because of the story of the Tanzanian artist who won the contest. Most conference attendees (11/12) preferred the crowdsourced logo compared with the previous company-organized logo, and all (22/22) supported the logo contest continuing. Implementing a logo contest was simple and relatively inexpensive. Stakeholders identified several ways to enhance crowdsourcing logo contest methods including wider promotion of the contest to encourage broader participation, greater transparency in the selection process, and a different prize structure which acknowledges the contribution of more contestants. We found that a crowdsourcing contest helped engage local and global communities in the lead-up before and during an international conference. Similar participatory events may be useful for sexual health conferences and research projects.

  15. Improving the Spiritual Dimension of Whole Person Care: Reaching National and International Consensus

    PubMed Central

    Vitillo, Robert; Hull, Sharon K.; Reller, Nancy

    2014-01-01

    Abstract Two conferences, Creating More Compassionate Systems of Care (November 2012) and On Improving the Spiritual Dimension of Whole Person Care: The Transformational Role of Compassion, Love and Forgiveness in Health Care (January 2013), were convened with the goals of reaching consensus on approaches to the integration of spirituality into health care structures at all levels and development of strategies to create more compassionate systems of care. The conferences built on the work of a 2009 consensus conference, Improving the Quality of Spiritual Care as a Dimension of Palliative Care. Conference organizers in 2012 and 2013 aimed to identify consensus-derived care standards and recommendations for implementing them by building and expanding on the 2009 conference model of interprofessional spiritual care and its recommendations for palliative care. The 2013 conference built on the 2012 conference to produce a set of standards and recommended strategies for integrating spiritual care across the entire health care continuum, not just palliative care. Deliberations were based on evidence that spiritual care is a fundamental component of high-quality compassionate health care and it is most effective when it is recognized and reflected in the attitudes and actions of both patients and health care providers. PMID:24842136

  16. 2008 Co2 Assimilation in Plants: Genome to Biome Gordon Research Conference - August 17-22

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    James V. Maroney

    2009-08-12

    Formerly entitled 'CO2 Fixation and Metabolism in Green Plants', this long-standing Gordon Research Conference has been held on a triennial basis since 1976. In 1990 the participants decided to alternate between sites in the U.S. and outside the U.S. The 2005 conference was held in Europe at the Centre Paul Langevin in Aussois, France, so the 2008 conference returns to a U.S. site - the University of New England in Biddeford, Maine. The 2008 conference covers basic plant research related to photosynthesis and the subsequent regulation and engineering of carbon assimilation. Approaches that range from post-genomic technologies and systems biology,more » through to fundamental biochemistry, physiology and molecular biology are integrated within ecological and agronomic contexts. As such, the meeting provides the rare opportunity of a single venue for discussing all aspects of the 'carbon-side' of photosynthesis - from genome to biome. The 2008 conference will include an emphasis on the central role of carbon assimilation by plants for developing new sources of bioenergy and for achieving a carbon-neutral planet. A special characteristic of this conference is its 'intimacy' with approximately 110 conferees, ranging from beginning graduate students and postdoctoral associates to leading senior plant scientists, engaged in open and forward-thinking discussions in an informal, friendly setting. With extended time devoted to discussion, and the encouragement to challenge dogma, it is unlike other meetings in the U.S. or abroad. Another novel feature of the conference is a session devoted to the latest 'hot off the press' findings by both established and early career scientists, picked from the abstracts. Together with an expanded poster discussion in the evening sessions, this session provides an opportunity for early career scientists to present interesting new data and to 'test drive' hypotheses in a collegial atmosphere.« less

  17. Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic

    PubMed Central

    Bird, Gregory H.; Madani, Navid; Perry, Alisa F.; Princiotto, Amy M.; Supko, Jeffrey G.; He, Xiaoying; Gavathiotis, Evripidis; Sodroski, Joseph G.; Walensky, Loren D.

    2010-01-01

    The pharmacologic utility of lengthy peptides can be hindered by loss of bioactive structure and rapid proteolysis, which limits bioavailability. For example, enfuvirtide (Fuzeon, T20, DP178), a 36-amino acid peptide that inhibits human immunodeficiency virus type 1 (HIV-1) infection by effectively targeting the viral fusion apparatus, has been relegated to a salvage treatment option mostly due to poor in vivo stability and lack of oral bioavailability. To overcome the proteolytic shortcomings of long peptides as therapeutics, we examined the biophysical, biological, and pharmacologic impact of inserting all-hydrocarbon staples into an HIV-1 fusion inhibitor. We find that peptide double-stapling confers striking protease resistance that translates into markedly improved pharmacokinetic properties, including oral absorption. We determined that the hydrocarbon staples create a proteolytic shield by combining reinforcement of overall α-helical structure, which slows the kinetics of proteolysis, with complete blockade of peptide cleavage at constrained sites in the immediate vicinity of the staple. Importantly, double-stapling also optimizes the antiviral activity of HIV-1 fusion peptides and the antiproteolytic feature extends to other therapeutic peptide templates, such as the diabetes drug exenatide (Byetta). Thus, hydrocarbon double-stapling may unlock the therapeutic potential of natural bioactive polypeptides by transforming them into structurally fortified agents with enhanced bioavailability. PMID:20660316

  18. Crystal structure of the avilamycin resistance-conferring methyltransferase AviRa from Streptomyces viridochromogenes.

    PubMed

    Mosbacher, Tanja G; Bechthold, Andreas; Schulz, Georg E

    2003-05-23

    The emergence of antibiotic-resistant bacterial strains is a widespread problem in contemporary medical practice and drug design. It is therefore important to elucidate the underlying mechanism in each case. The methyltransferase AviRa from Streptomyces viridochromogenes mediates resistance to the antibiotic avilamycin, which is closely related to evernimicin, an oligosaccharide antibiotic that has been used in medical studies. The structure of AviRa was determined by X-ray diffraction at 1.5A resolution. Phases were obtained from one selenomethionine residue introduced by site-directed mutagenesis. The chain-fold is similar to that of most methyltransferases, although AviRa contains two additional helices as a specific feature. A putative-binding site for the cofactor S-adenosyl-L-methionine was derived from homologous structures. It agrees with the conserved pattern of interacting amino acid residues. AviRa methylates a specific guanine base within the peptidyltransferase loop of the 23S ribosomal RNA. Guided by the target, the enzyme was docked to the cognate ribosomal surface, where it fit well into a deep cleft without contacting any ribosomal protein. The two additional alpha-helices of AviRa filled a depression in the surface. Since the transferred methyl group of the cofactor is in a pocket beneath the enzyme surface, the targeted guanine base has to flip out for methylation.

  19. The Toxoplasma gondii cyst wall protein CST1 is critical for cyst wall integrity and promotes bradyzoite persistence

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tomita, Tadakimi; Bzik, David J.; Ma, Yan Fen

    2013-12-26

    Toxoplasma gondii infects up to one third of the world’s population. A key to the success of T.gondii is its ability to persist for the life of its host as bradyzoites within tissue cysts. The glycosylated cyst wall is the key structural feature that facilitates persistence and oral transmission of this parasite. We have identified CST1 (TGME49_064660) as a 250 kDa SRS (SAG1 related sequence) domain protein with a large mucin-like domain. CST1 is responsible for the Dolichos biflorus Agglutinin (DBA) lectin binding characteristic of T. gondii cysts. Deletion of CST1 results in a fragile brain cyst phenotype revealed bymore » a thinning and disruption of the underlying region of the cyst wall. These defects are reversed by complementation of CST1. Additional complementation experiments demonstrate that the CST1-mucin domain is necessary for the formation of a normal cyst wall structure, the ability of the cyst to resist mechanical stress and binding of DBA to the cyst wall. RNA-seq transcriptome analysis demonstrated dysregulation of bradyzoite genes within the various cst1 mutants. These results indicate that CST1 functions as a key structural component that reinforces the cyst wall structure and confers essential sturdiness to the T. gondii tissue cyst.« less

  20. New Advances and Challenges of Targeting Cancer Stem Cells.

    PubMed

    Dashzeveg, Nurmaa K; Taftaf, Rokana; Ramos, Erika K; Torre-Healy, Luke; Chumakova, Anastasia; Silver, Daniel J; Alban, Tyler J; Sinyuk, Maksim; Thiagarajan, Praveena S; Jarrar, Awad M; Turaga, Soumya M; Saygin, Caner; Mulkearns-Hubert, Erin; Hitomi, Masahiro; Rich, Jeremy N; Gerson, Stanton L; Lathia, Justin D; Liu, Huiping

    2017-10-01

    The second International Cancer Stem Cell Conference in Cleveland, Ohio, on September 20-23, 2016, convened 330 attendees from academic, industrial, and clinical organizations. It featured a debate on the concepts and challenges of the cancer stem cells (CSC) as well as CSC-centered scientific sessions on clinical trials, genetics and epigenetics, tumor microenvironment, immune suppression, metastasis, therapeutic resistance, and emerging novel concepts. The conference hosted 35 renowned speakers, 100 posters, 20 short talks, and a preconference workshop. The reported advances of CSC research and therapies fostered new collaborations across national and international borders, and inspired the next generation's young scientists. Cancer Res; 77(19); 5222-7. ©2017 AACR . ©2017 American Association for Cancer Research.

  1. Self-help conferences for people who stutter: a qualitative investigation.

    PubMed

    Trichon, Mitchell; Tetnowski, John

    2011-12-01

    Self-help activities for people who stutter (PWS) have been gaining in popularity; however, there is a scarcity of evidence to support their utility in stuttering management. The purpose of this investigation was to understand the lived experience of individuals who attended a self-help conference(s) for PWS from the perspective of a PWS to learn its potential utility in stuttering management. The investigator used Interpretive Phenomenological Analysis (IPA) to systematically collect authentic data of this social phenomenon. Twelve participants were recruited from a self-help conference and the self-help community of PWS. Semi-structured interviews were conducted 4-18 months after each participant's last conference. Interviews were transcribed and analyzed. Themes were explained in investigator narratives and illustrated through participants' quotes. Interpreted themes of the experience of having attended a self-help conference(s) for PWS included: socializing opportunities with other PWS, affiliation, redefining oneself and post-conference disclosures. A conclusion of the study was that the experience of having attended a self-help conference(s) for PWS helped to minimize negative impact that stuttering can have on daily functioning. It appears that self-help conferences were perceived as a safer or "stutter-friendly" environment and promoted social interaction, relationship building, and community building through planned and unplanned activities. Another conclusion was that the experience of having attended self-help conferences for PWS helped participants to communicate more easily. Reported increases in social activity and an "openness" about stuttering, suggest self-help conferences' utility in stuttering management. These findings are supported by other studies about successful stuttering management and self-help activities for PWS. They have helped attendees who stutter to communicate more easily and suggest a reduction in the negative impact that stuttering has on their lives. The reader will be able to: (1) describe recurring themes associated with the lived experience having attended a self-help conference(s) for people who stutter (PWS) from the perspective of a group of adults who stutter, and (2) describe the potential benefits of attending self-help conferences for PWS in order to make appropriate evidence-based referrals to self-help conferences for PWS. Copyright © 2011 Elsevier Inc. All rights reserved.

  2. 2010 CATALYSIS GORDON RESEARCH CONFERENCE, JUNE 27 - JULY 2, 2010, NEW LONDON, NEW HAMPSHIRE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abhaya Datye

    2010-07-02

    Catalysis is a key technology for improving the quality of life while simultaneously reducing the adverse impact of human activities on the environment. The discovery of new catalytic processes and the improvement of existing ones are also critically important for securing the nation's energy supply. The GRC on Catalysis is considered one the most prestigious conference for catalysis research, bringing together leading researchers from both academia, industry and national labs to discuss the latest, most exciting research in catalysis and the future directions for the field. The 2010 GRC on Catalysis will follow time-honored traditions and feature invited talks frommore » the world's leading experts in the fundamentals and applications of catalytic science and technology. We plan to have increased participation from industry. The extended discussions in the company of outstanding thinkers will stimulate and foster new science. The conference will include talks in the following areas: Alternative feedstocks for chemicals and fuels, Imaging and spectroscopy, Design of novel catalysts, Catalyst preparation fundamentals, Molecular insights through theory, Surface Science, Catalyst stability and dynamics. In 2010, the Catalysis conference will move to a larger conference room with a new poster session area that will allow 40 posters per session. The dorm rooms provide single and double accommodations, free WiFi and the registration fee includes all meals and the famous lobster dinner on Thursday night. Afternoons are open to enjoy the New England ambiance with opportunities for hiking, sailing, golf and tennis to create an outstanding conference that will help you network with colleagues, and make long lasting connections.« less

  3. 27th International Conference on CADCAM, Robotics and Factories of the Future 2014

    NASA Astrophysics Data System (ADS)

    Karamanoglu, Mehmet; Yang, Xin-She; Zivanovic, Aleksandar; Smith, Martin; Loureiro, Rui

    2014-07-01

    It is a great pleasure to welcome you to the 27th International Conference on CADCAM, Robotics and Factories of the Future, sponsored by the International Society for Productivity Enhancement, Middlesex University, Festo Limited GB, National Instruments UK & Ireland, the Sector Skills Council for Science, Engineering and Manufacturing Technologies and our proceedings publisher Institute of Physics Publications. This is the second time Middlesex University has played host to this longstanding international conference, last time being the 12th edition in 1996. The subject content of the conference remains current, focusing on cutting edge developments in research. The conference themes this year are divided into seven themes, Product Development and Sustainability, Modelling and Simulation, Automation, Robotics and Handling Systems, Advanced Quality Systems Tools and Quality Management, Human Aspects in Engineering Activities, Emerging Scenarios in Engineering Education and Training, and Emerging Technologies in Factories of the Future. The conference is organised into seven sessions running in parallel over three days, providing a platform to speakers from 16 different countries. The programme also features four eminent keynote speakers and a hands-on workshop organised by National Instruments. Organising an event such as this would not be possible without the help of many colleagues. I am grateful to the members of the Organising Committee, the International Scientific Committee, our sponsors and all those colleagues who helped in the review of many abstracts and consequently full papers. This required meticulous attention to detail and strict adherence to very tight deadlines. However large or small a conference is, the effort required to make the local arrangements work for all is not insignificant. The conference organisers acknowledge the particular efforts of Miss Mita Vaghi in providing her expertise in event management and her diligent support and Anete Ashton of IoP Publications for her guidance and help in producing the conference proceedings and online listing. The organisers also recognise the support provided by our sponsors and in particular to Richard Roberts and David Baker from National Instruments, Babak Jahanbani and Phil Holmes from Festo Ltd. Their continued support over the course of the planning period and also during the event itself is very much appreciated. We are also indebted to all the contributors to the conference, particularly the researchers, and practitioners. Professor Mehmet Karamanoglu Conference Chair Further details, including keynote speakers and committees, are available in the PDF

  4. Distributive Marketing Education: Innovative Instructional Techniques in Distributive Marketing Education.

    ERIC Educational Resources Information Center

    Office of Education (DHEW), Washington, DC.

    The conference featured more than 40 presentations representing existing and planned innovative programs in all levels of distributive marketing education in six States. In addition to the presentations (not reproduced in their entirety in the report), there were sessions and workshops for secondary, post secondary, and adult levels and for city…

  5. Maximizing Student Achievement: Using Student-Centered Learning

    ERIC Educational Resources Information Center

    Johnson, William L.; Johnson, Annabel M.; Johnson, Jared W.

    2017-01-01

    The document is from a featured presentation at the 2017 annual conference of the Science Teachers Association of Texas (STAT) in Houston, Texas, November 9-11, 2017. When educators discuss student achievement, it is rare not to hear names like Robert Marzano and John Hattie. Both have clear, specific, and concrete strategies teachers can use to…

  6. Authors, Authors, Authors

    ERIC Educational Resources Information Center

    Harvey, Carl A., II; Kaplan, Allison G.

    2007-01-01

    This article features some of the programs offered in the Reno conference. Two of the preconferences at Reno will focus on children's literature. Judy Freeman will talk about some of the current and future trends for books for younger readers. She will share a plethora of some of the best picture books and chapter books. Ruth Cox Clark will take…

  7. Visual Communication in PowerPoint Presentations in Applied Linguistics

    ERIC Educational Resources Information Center

    Kmalvand, Ayad

    2014-01-01

    PowerPoint knowledge presentation as a digital genre has established itself as the main software by which the findings of theses are disseminated in the academic settings. Although the importance of PowerPoint presentations is typically realized in academic settings like lectures, conferences, and seminars, the study of the visual features of…

  8. Practical Work Using Low-Level Radioactive Materials Available to the Public

    ERIC Educational Resources Information Center

    Whitcher, Ralph

    2011-01-01

    These notes describe six practical activities for supplementing standard practical work in radioactivity. They are based on a series of workshops given at ASE regional and national conferences by the ASE's Safeguards in Science Committee. The activities, which demonstrate aspects of radioactivity, feature consumer items that happen to be…

  9. The Presidential Address 2014. Teaching and Learning: The Long View

    ERIC Educational Resources Information Center

    Roberts, Alice

    2014-01-01

    This article presents the transcript of the Presidential Address delivered to the Association for Science Education Annual Conference held at the University of Birmingham in January 2014. In her address, Alice Roberts traces the evolution of various features that are often thought to make humans different from other animals. Examples such as…

  10. Multiplicity and Self-Identity: Trauma and Integration in Shirley Mason's Art

    ERIC Educational Resources Information Center

    Thompson, Geoffrey

    2011-01-01

    This viewpoint appeared in its original form as the catalogue essay that accompanied the exhibition "Multiplicity and Self-Identity: Trauma and Integration in Shirley Mason's Art," curated by the author for Gallery 2110, Sacramento, CA, and the 2010 Annual Conference of the American Art Therapy Association. The exhibition featured 17 artworks by…

  11. Sites Mimicking Social Networks Set Up for Staff Development

    ERIC Educational Resources Information Center

    Sawchuk, Stephen

    2008-01-01

    As support and professional-development opportunities for teachers begin to move from conference rooms to chat rooms, a burgeoning number of states and districts are drawing on features from course-management software and popular social-networking sites to establish online networks connecting teachers to peers who may live dozens or even hundreds…

  12. Winter-Deciduous versus Evergreen Habit in Mediterranean Regions: A Model

    Treesearch

    Mark A. Blumler

    1991-01-01

    Although winter-deciduous species are presumed to be "out-of-phase" with the mediterranean climate regime, distributional evidence suggests some taxa may be more tolerant of summer drought than evergreen sclerophylls. Deciduous species possess several features that confer advantage in extreme summer dry regions: drought-deciduousness, an efficient response to...

  13. DefenseLink Feature:

    Science.gov Websites

    You have reached a collection of archived material. The content available is no longer being updated and may no longer be applicable as a result of changes in law, regulation and/or administration Civilian Orientation Conference load a U.S. Navy Cod aircraft after a day trip to the USS George Washington

  14. "Let's Get Smart about Art": Developing Visual Literacy with Picture Books

    ERIC Educational Resources Information Center

    McNair, Jonda C.; Colabucci, Lesley

    2007-01-01

    During the post-convention of the 2006 National Council of Teachers of English Conference, members of the Children's Literature Assembly organized and sponsored a day-long workshop on the subject of developing visual literacy within the context of picture books. The workshop featured children's book illustrators (LeUyen Pham, Margaret…

  15. Developing and Running a WWW Biology Course.

    ERIC Educational Resources Information Center

    Collins, Michael

    1997-01-01

    Describes the development of a World Wide Web version of a second-year biology class. Discusses features of the course and its organization as well as interaction with the instructor and other class members through e-mail and a Web conference. Course satisfaction was high with a main positive aspect being students' ability to schedule learning…

  16. A Brief History of Service-Learning Internship Programs.

    ERIC Educational Resources Information Center

    Corey, John F., Ed.

    1972-01-01

    Recent educational conferences indicate not only that community-based experiential learning has grown dramatically in recent years as a curricular feature of higher education, but also that this empirical learning style is to be a major trend in the immediate academic future of the nation. The State of North Carolina has, since 1969, supported…

  17. The Louisiana PIP Program: An Innovative Step Toward Quality Public Education or an Unmanageable Hydra.

    ERIC Educational Resources Information Center

    Chachere, Ernest G.; Nowatny, Franz A.

    1982-01-01

    Louisiana's Educational Employees' Professional Improvement Program (PIP) is described. The voluntary statewide program features: (1) use of individual professional development plans submitted by school staff participants; (2) a combination of academic work, inservice training, workshops, and conferences over a five-year period; and (3) salary…

  18. Lessons from New Zealand: Developing Student Voices with Technology

    ERIC Educational Resources Information Center

    Charles, Mike; Burt, Dorothy; Williams, Mia Kim

    2011-01-01

    Thirteen members of ISTE's Special Interest Group for Teacher Educators (SIGTE) traveled to Auckland, Rotorua, and Christchurch to visit seven schools and present and attend the Learning@School 2010 conference as part of a travel tour last February. This second installment about their trip features ways they saw technology used in New Zealand to…

  19. Evolutionary outcomes should inform plant breeding and transgenic approaches to drought tolerance in crop species: the importance of xylem traits

    USDA-ARS?s Scientific Manuscript database

    Genomic-assisted breeding and transgenic approaches to crop improvement are presently targeting phenotypic traits that allegedly confer drought tolerance. A news feature published in Nature Biotechnology last year suggests that these efforts may not be proceeding with sufficient haste, considering t...

  20. Lost in Translation: Western Representations of Maori Knowledge

    ERIC Educational Resources Information Center

    Mika, Carl; Stewart, Georgina

    2017-01-01

    We recently attended a conference at which a non-Maori presenter, drawing on a particular metaphor already established by Maori writers, related Maori natural world features to a research method. The presentation was useful because it highlighted several issues that call for our concern as Maori philosophers. In this article, we outline these…

  1. Toward an Evaluation Strategy for FAP-Day Care.

    ERIC Educational Resources Information Center

    Datta, Lois-ellin, Ed.

    This report presents the findings of an invitational conference sponsored by the Office of Child Development to assess the implications of Family Assistance Plan (FAP) day care provisions from the viewpoint of program evaluation. The first section outlines the features of FAP day care, and the second section identifies accountability issues for…

  2. Statistical and Adaptive Signal Processing for UXO Discrimination for Next-Generation Sensor Data

    DTIC Science & Technology

    2009-09-01

    using the energies of all polarizations as features in a KNN classifier variant resulted in 100% probability of detection at a probability of false...International Conference on Acoustics, Speech , and Signal Processing, vol. V, 2005, pp. 885-888. [12] C. Kreucher, K. Kastella, and A. O. Hero

  3. CHAIRMAN'S FOREWORD: First International Symposium on Advanced Nanodevices and Nanotechnology

    NASA Astrophysics Data System (ADS)

    Aoyagi, Yoshinobu; Goodnick, Stephen M.

    2008-03-01

    This volume of Journal of Physics: Conference Series contains selected papers from the First International Symposium on Advanced Nanodevices and Nanotechnology. This conference is a merging of the two previous series New Phenomena in Mesoscopic Structures and the Surfaces and Interfaces of Mesoscopic Devices. This year's conference was held 2-7 December 2007 at the Waikoloa Beach Marriott on the Kohala coast of the big island of Hawaii. The scope of ISANN spans nano-fabrication through complex phase coherent mesoscopic systems including nano-transistors and nano-scale characterization. Topics of interest included: Nano-scale fabrication (high-resolution electron lithography, FIB nano-patterning SFM lithography, SFM stimulated growth, novel patterning, nano-imprint lithography, special etching, and SAMs) Nano-characterization (SFM characterization, BEEM, optical studies of nanostructures, tunneling, properties of discrete impurities, phase coherence, noise, THz studies, electro-luminescence in small structures) Nano-devices (ultra-scaled FETs, quantum SETs, RTDs, ferromagnetic, and spin devices, superlattice arrays, IR detectors with quantum dots and wires, quantum point contacts, non-equilibrium transport, simulation, ballistic transport, molecular electronic devices, carbon nanotubes, spin selection devices, spin-coupled quantum dots, nano-magnetics) Quantum coherent transport (quantum Hall effect, ballistic quantum systems, quantum computing implementations and theory, magnetic spin systems, quantum NEMs) Mesoscopic structures (quantum wires and dots, chaos, non-equilibrium transport, instabilities, nano-electro-mechanical systems, mesoscopic Josephson effects, phase coherence and breaking, Kondo effect) Systems of nano-devices (QCAs, systolic SET processors, quantum neural nets, adaptive effects in circuits, molecular circuits, NEMs) Nanomaterials (nanotubes, nanowires, organic and molecular materials, self-assembled nanowires, organic devices) Nano-bio-electronics (electronic properties of biological structures on the nanoscale) We were very pleased and honored to have the opportunity to organize the first International Symposium on Advanced Nanodevices and Nanotechnology. The conference benefited from 14 invited speakers, whose topics spanned the above list, and a total of 90 registered attendees. The largest contingent was from Japan, followed closely by the USA. We wish to particularly thank the sponsors for the meeting: Arizona State University on the US side, and the Japan Society for the Promotion of Science, through their 151 Committee, on the Japanese side. We would also like to thank Dr Koji Ishibashi, of RIKEN, for his assistance in the organization of the conference, and Professor David K Ferry for serving as the Editor for the ISANN Proceedings. Yoshinobu Aoyagi and Stephen M Goodnick Conference Co-Chairs

  4. Structural Integrity and Durability of Reusable Space Propulsion Systems

    NASA Technical Reports Server (NTRS)

    1987-01-01

    A two-day conference on the structural integrity and durability of reusable space propulsion systems was held on May 12 and 13, 1987, at the NASA Lewis research Center. Aerothermodynamic loads; instrumentation; fatigue, fracture, and constitutive modeling; and structural dynamics were discussed.

  5. Environmental Problems: A Global Security Threat. Report of the United Nations of the Next Decade Conference (24th, Hamilton Parish, Bermuda, June 18-23, 1989).

    ERIC Educational Resources Information Center

    Stanley Foundation, Muscatine, IA.

    The world's political structure and many economic practices are out of harmony with nature. This disharmony threatens environmentally sustainable growth and human survival. United Nations (UN) conference participants discussed the degree of political acceptance of concepts such as environmental security and sustainable development. Their reading…

  6. Thematic Structure in Barack Obama's Press Conference: A Systemic Functional Grammar Study

    ERIC Educational Resources Information Center

    Kuswoyo, Heri

    2016-01-01

    This article looks into the theme--rheme pattern of presidential press conference that can be employed by speakers to organize the text in order to have a texture. Since a message should be conveyed in clause contextually and co-textually. Therefore, the objectives of this study are to analyze and describe the theme-rheme pattern employed in…

  7. Key Stage 3 Mathematics Teachers: The Current Situation, Initiatives and Visions. Proceedings of a National Day Conference.

    ERIC Educational Resources Information Center

    Johnston-Wilder, Sue

    This book contains edited versions of papers presented at a conference held at The Open University. The papers provide significant evidence of the depth of the problem of supply and retention of teachers of mathematics, and discusses the need for a structural review of the recruitment, selection, and training of teachers of mathematics. The…

  8. Development Problems With Component Construction. Proceedings of Conference of the Building Research Institute, Division of Engineering and Industrial Research (Fall 1959).

    ERIC Educational Resources Information Center

    National Academy of Sciences - National Research Council, Washington, DC.

    Publication of conference papers includes--(1) an overview of the ceiling system complex by a lighting manufacturer, (2) review of problems influencing the development of roofing systems, (3) description of cooperative research within the cement industry, and (4) description of joint research development of structural ceramic panels. Included…

  9. Leadership in Boys' Education: 16 Case Studies from Public and Private, Rural and Urban, Primary and Secondary Schools.

    ERIC Educational Resources Information Center

    Fletcher, Richard, Ed.; Hartman, Deborah, Ed.; Browne, Rollo, Ed.

    Concern about boys' education in Australia and New Zealand led to the Leadership in Boys' Education Conference in May 1999. This book contains edited conference presentations focusing on boys' educational needs. The book also presents case studies related to academic achievement, school structure, discipline and bullying, broadening boys' options,…

  10. Analysis and Reflections on the Third Learning Analytics and Knowledge Conference (LAK 2013)

    ERIC Educational Resources Information Center

    Ochoa, Xavier; Suthers, Dan; Verbert, Katrien; Duval, Erik

    2014-01-01

    Analyzing a conference, especially one as young and focused as LAK, provides the opportunity to observe the structure and contributions of the scientific community around it. This work will perform a Scientometric analysis, coupled with a more in-depth manual content analysis, to extract this insight from the proceedings and program of LAK 2013.…

  11. A scoping review about conference objectives and evaluative practices: how do we get more out of them?

    PubMed

    Neves, Justin; Lavis, John N; Ranson, M Kent

    2012-08-02

    Large multi-day conferences have often been criticized as ineffective ways to improve social outcomes and to influence policy or practice. Unfortunately, many conference evaluations have also been inadequate in determining the impact of a conference on its associated social sector, with little evidence gathered or analyzed to substantiate or refute these criticisms. The aim of this scoping review is to investigate and report stakeholders' objectives for planning or participating in large multi-day conferences and how these objectives are being evaluated. We conducted a scoping review supplemented by a small number of key informant interviews. Eight bibliographic databases were systematically searched to identify papers describing conference objectives and/or evaluations. We developed a conference evaluation framework based on theoretical models and empirical findings, which structured the descriptive synthesis of the data. We identified 3,073 potential papers for review, of which 44 were included in this study. Our evaluation framework connects five key elements in planning a conference and its evaluation (number in brackets refers to number of themes identified): conference objectives (8), purpose of evaluation (7), evaluation methods (5), indicators of success (9) and theories/models (8). Further analysis of indicators of success identified three categories of indicators with differing scopes (i.e. immediate, prospective or follow-up) as well as empirical links between the purpose of evaluations and these indicators. Conference objectives and evaluations were largely correlated with the type of conference (i.e. academic, political/governmental or business) but diverse overall. While much can be done to improve the quality and usefulness of conference evaluations, there are innovative assessments that are currently being utilized by some conferences and warrant further investigation. This review provides conference evaluators and organizers a simple resource to improve their own assessments by highlighting and categorizing potential objectives and evaluation strategies.

  12. A scoping review about conference objectives and evaluative practices: how do we get more out of them?

    PubMed Central

    2012-01-01

    Large multi-day conferences have often been criticized as ineffective ways to improve social outcomes and to influence policy or practice. Unfortunately, many conference evaluations have also been inadequate in determining the impact of a conference on its associated social sector, with little evidence gathered or analyzed to substantiate or refute these criticisms. The aim of this scoping review is to investigate and report stakeholders’ objectives for planning or participating in large multi-day conferences and how these objectives are being evaluated. We conducted a scoping review supplemented by a small number of key informant interviews. Eight bibliographic databases were systematically searched to identify papers describing conference objectives and/or evaluations. We developed a conference evaluation framework based on theoretical models and empirical findings, which structured the descriptive synthesis of the data. We identified 3,073 potential papers for review, of which 44 were included in this study. Our evaluation framework connects five key elements in planning a conference and its evaluation (number in brackets refers to number of themes identified): conference objectives (8), purpose of evaluation (7), evaluation methods (5), indicators of success (9) and theories/models (8). Further analysis of indicators of success identified three categories of indicators with differing scopes (i.e. immediate, prospective or follow-up) as well as empirical links between the purpose of evaluations and these indicators. Conference objectives and evaluations were largely correlated with the type of conference (i.e. academic, political/governmental or business) but diverse overall. While much can be done to improve the quality and usefulness of conference evaluations, there are innovative assessments that are currently being utilized by some conferences and warrant further investigation. This review provides conference evaluators and organizers a simple resource to improve their own assessments by highlighting and categorizing potential objectives and evaluation strategies. PMID:22857399

  13. [Twenty-second conference of the Czechoslovak Demographic Society: "The Demographic Position of Czechoslovakia within Europe and the World"].

    PubMed

    Fialova, L; Rychtarikova, J; Roubicek, V; Stloukal, L; Veres, P; Koschin, F; Novakova, B; Pavlik, Z

    1992-01-01

    This is a collection of short papers presented at a conference held in Prague, Czechoslovakia, in 1991. The focus of the conference was on the demographic changes that have occurred in Czechoslovakia since World War II and their relationship to such changes in the rest of Europe and elsewhere in the world. Essay topics include fertility trends; contraceptive prevalence, including abortion rates; living standards and health care; and changes in the age structure. Some data for selected countries are included for comparison. (SUMMARY IN ENG AND RUS)

  14. pSTM6-275, a Conjugative IncHI2 Plasmid of Salmonella enterica That Confers Antibiotic and Heavy-Metal Resistance under Changing Physiological Conditions.

    PubMed

    Billman-Jacobe, Helen; Liu, Yuhong; Haites, Ruth; Weaver, Tom; Robinson, Lily; Marenda, Marc; Dyall-Smith, Mike

    2018-05-01

    Detailed annotation of an IncHI2 plasmid, pSTM6-275, from Salmonella enterica serotype 1,4,5,12:i:- strain TW-Stm6 revealed a composite structure, including antimicrobial resistance genes on mobile genetic elements. The plasmid was thermosensitive for transfer to Escherichia coli and conferred reduced susceptibility to antibiotics, copper sulfate, and silver nitrate. Metal ion susceptibility was dependent on physiological conditions, giving an insight into the environments where this trait might confer a fitness advantage. Copyright © 2018 Billman-Jacobe et al.

  15. Dimensionally stable composite structures and composite mirrors for spaceborne optical instruments

    NASA Astrophysics Data System (ADS)

    Sippel, Rudolf; Stute, Thomas; Erdl, Günther

    2018-04-01

    This paper, "Dimensionally stable composite structures and composite mirrors for spaceborne optical instruments," was presented as part of International Conference on Space Optics—ICSO 1997, held in Toulouse, France.

  16. Structure and function of echinoderm telomerase RNA

    PubMed Central

    Podlevsky, Joshua D.; Li, Yang; Chen, Julian J.-L.

    2016-01-01

    Telomerase is a ribonucleoprotein (RNP) enzyme that requires an integral telomerase RNA (TR) subunit, in addition to the catalytic telomerase reverse transcriptase (TERT), for enzymatic function. The secondary structures of TRs from the three major groups of species, ciliates, fungi, and vertebrates, have been studied extensively and demonstrate dramatic diversity. Herein, we report the first comprehensive secondary structure of TR from echinoderms—marine invertebrates closely related to vertebrates—determined by phylogenetic comparative analysis of 16 TR sequences from three separate echinoderm classes. Similar to vertebrate TR, echinoderm TR contains the highly conserved template/pseudoknot and H/ACA domains. However, echinoderm TR lacks the ancestral CR4/5 structural domain found throughout vertebrate and fungal TRs. Instead, echinoderm TR contains a distinct simple helical region, termed eCR4/5, that is functionally equivalent to the CR4/5 domain. The urchin and brittle star eCR4/5 domains bind specifically to their respective TERT proteins and stimulate telomerase activity. Distinct from vertebrate telomerase, the echinoderm TR template/pseudoknot domain with the TERT protein is sufficient to reconstitute significant telomerase activity. This gain-of-function of the echinoderm template/pseudoknot domain for conferring telomerase activity presumably facilitated the rapid structural evolution of the eCR4/5 domain throughout the echinoderm lineage. Additionally, echinoderm TR utilizes the template-adjacent P1.1 helix as a physical template boundary element to prevent nontelomeric DNA synthesis, a mechanism used by ciliate and fungal TRs. Thus, the chimeric and eccentric structural features of echinoderm TR provide unparalleled insights into the rapid evolution of telomerase RNP structure and function. PMID:26598712

  17. Special Issue the 12th International Conference on Substorms

    NASA Technical Reports Server (NTRS)

    Shiokawa, Kazuo; Fok, Mei-Ching; Fujimoto, Masaki

    2016-01-01

    The 12th International Conference on Substorms (ICS-12) was held at the Ise-Shima Royal Hotel in Shima, Japan, on November 10-14, 2014. There were 125 attendees including 68 from foreign countries. The ICS has been held every 2 years since 1992 to discuss substorms, which are fundamental global-scale disturbances in the Earth's magnetosphere. The year 2014 marked the 50th anniversary of the first publication about substorms (Akasofu 1964). The conference included three tutorial lecturers (Profs. S.-I. Akasofu, V. Angelopoulous, and D. Baker), as well as many international scientists, to discuss substorm processes in the tail, their Interactions with the inner magnetosphere and the ionosphere, substorm currents and their dynamics and energetics, the role of MagnetoHydroDynamics (MHD) and kinetic instabilities, storm-substorm relationships, ULFELFVLF waves, and non-Earth substorm-like features. Prof. Akasofu also gave an evening talk about the history of auroral research since the nineteenth century with photographs that inspired and intrigued the young scientists and students in attendance.

  18. The Boundary Integral Equation Method for Porous Media Flow

    NASA Astrophysics Data System (ADS)

    Anderson, Mary P.

    Just as groundwater hydrologists are breathing sighs of relief after the exertions of learning the finite element method, a new technique has reared its nodes—the boundary integral equation method (BIEM) or the boundary equation method (BEM), as it is sometimes called. As Liggett and Liu put it in the preface to The Boundary Integral Equation Method for Porous Media Flow, “Lately, the Boundary Integral Equation Method (BIEM) has emerged as a contender in the computation Derby.” In fact, in July 1984, the 6th International Conference on Boundary Element Methods in Engineering will be held aboard the Queen Elizabeth II, en route from Southampton to New York. These conferences are sponsored by the Department of Civil Engineering at Southampton College (UK), whose members are proponents of BIEM. The conferences have featured papers on applications of BIEM to all aspects of engineering, including flow through porous media. Published proceedings are available, as are textbooks on application of BIEM to engineering problems. There is even a 10-minute film on the subject.

  19. PREFACE: 13th International Conference on Liquid and Amorphous Metals

    NASA Astrophysics Data System (ADS)

    Popel, Pjotr; Gelchinskii, Boris; Sidorov, Valeriy; Son, Leonid; Sabirzjanov, Alexandre

    2007-06-01

    The state of the art in the field of liquid and amorphous metals and alloys is regularly updated through two series of complementary international conferences, the LAM (Liquid and Amorphous Metals) and the RQ (Rapidly Quenched Materials). The first series of the conferences started as LM-1 in 1966 at Brookhaven for the basic understanding of liquid metals. The subsequent LM conferences were held in Tokyo (1972) and Bristol (1976). The conference was renewed in Grenoble (1980) as a LAM conference including amorphous metals and continued in Los Angeles (1983), Garmisch-Partenkirchen (1986), Kyoto (1989), Vienna (1992), Chicago (1995), Dortmund (1998), Yokohama (2001) and Metz (2004). The conferences are mainly devoted to liquid and amorphous metals and alloys. However, communications on some non-metallic systems such as semi conductors, quasicrystals etc, were accepted as well. The conference tradition strongly encourages the participation of junior researchers and graduate students. The 13th conference of the LAM series was organized in Ekaterinburg, Russia, by the Institute of Metallurgy of the Ural Branch of the Russian Academy of Sciences (IMet UB RAS) and Ural State Pedagogical University (USPU) and held on 8-13 July 2007 under the chairmanship of Professors Pjotr Popel (USPU) and Boris Gelchinskii (IMet UB RAS). There were 242 active and about 60 guest participants from 20 countries who attended the conference. There were no parallel sessions and all oral reports were separated into three groups: invited talks (40 min), full-scale (25 min) and brief (15 min) oral reports. The program included 10 sessions, ranging from purely theoretical subjects to technological application of molten and amorphous alloys. The following sessions took place: A) Electronic structure and transport, magnetic properties; B) Phase transitions; C) Structure; D) Atomic dynamics and transport; E) Thermodynamics; F) Modelling, simulation; G) Surface and interface; H) Mechanical properties and new materials; I) Quasicrystals; J) Industrial applications. The most representative sessions were E (53 reports), C (47), D (43) and F (40). All posters were exhibited during the first (sections A-E) or the last (sections F-J) three days of the conference. All the sessions took place in the Government House of Sverdlovsk Region where, in addition, everyone was able to enjoy dishes of Russian cuisine during lunches and coffee breaks. As usual, each oral session started from an invited talk. Therefore, 10 invited lecturers presented their reports. In accordance with contemporary tendency the first invited talk of M Yao (Kyoto University) was devoted to interrelations between liquid metal studies and nano-science. He pointed out that physics of disordered matter, especially liquid metals, has provided nano-science with basic ideas and theoretical tools such as ab initio MD simulation. K Tamura (Kyoto University) reported results of experimental investigation of expanded liquid rubidium showing that observed structural features originate from the instability of the low-density electron gas. Modern theory has predicted that interacting electron gas suffers a negative compressibility and the static dielectric-function (DF) becomes negative when electron density is sufficiently reduced. The negative DF is of special interest in connection with the possibility of a new type of superconductor. In the invited lecture of M I Mendelev and J R Morris (USA) MD simulations were performed to study phase transformations in supercooled liquid Al. The authors found that widely used EAM potential for Al provides vitrification for the cooling rates achievable in classical MD simulation, while other Al potentials provide crystallization under the same conditions. The reason for this difference, as well as features of the vitrification in the EA Al, were discussed. P Häussler (Chemnitz University) spoke about fundamental structure-forming processes in liquid and amorphous materials. He had proposed the resonance model as an autonomous missing link between the microscopic description of atoms/molecules, described by Schrödinger's equation, and the crystals where global concepts as planar resonances exist and Bloch's theorem is applied. D Holland-Moritz (Institut für Materialphysik, Köln) presented results of the first quasielastic neutron scattering experiments on electromagnetically levitated metallic melts. The studies are indicative of Arrhenius behaviour of the diffusion constants in the whole investigated temperature regime ranging from temperatures above the melting temperature up to the metastable regime of an undercooled liquid. L Son (USPU) discussed the existing analytical theories of liquid-liquid phase transitions that have been supposed for a wide variety of liquids, but are rather poorly understood analytically. The application of these theories to liquid metal systems was also demonstrated. An approach to study dynamics and kinetics of cavitation in stretched liquid metals by the classical molecular dynamics (MD) method was presented in the talk of G E Norman (Institute for High Temperatures, Moscow). Both quantitative and qualitative disagreements with the classic theory of homogeneous nucleation were found. Analytic extentions of MD results beyond the space and temporal limits accessible for the MD method were discussed also. G Wilde (University of Münster) spoke about experimental investigation of the impact of interface properties and, more specifically, of the interface morphology in matrix-encased metallic nanoparticles on macroscopic properties, such as melting transition by a combination of microscopic, microanalytical and calorimetric measurements. These results are discussed with respect to the underlying mechanisms that leads to size dependent phase equilibria. In the invited talk of V Keryvin (University of Rennes) the indentation ability was proposed to be used as a probe for pressure-sensitivity in metallic glasses. The main conclusion was: the indentation test provides good means to study the elasto-plastic behaviour of these materials as well as a relevant tool to subject them to multiaxial loadings. The influence of changes in local ordering of precursor melt on the formation of amorphous state and subsequent crystallization was a subject of a report presented by P Švec (Institute of Physics, Bratislava). The effect was shown for rapidly quenched Fe-Mo-B system with addition of Cu and substitution of Fe by Co prepared under varying conditions of planar flow casting and using master alloys with specific melt treatment. About 320 abstracts were received and 180 manuscripts were finally submitted for publication. All the papers followed invited lectures and full-scale oral reports were sent to the Journal of Physics: Condensed Matter for publication in a special issue. These papers will be published according to the current standard practices, policies and procedures of the Journal. All the papers following brief oral reports and posters were collected for this volume of Journal of Physics: Conference Series. All of them were edited by editors from Ekaterinburg. The Journal will provide access to all of the accepted papers free of charge via its web server. Afterwards, to publish and ship hardcopies of both the journals (Journal of Physics: Condensed Matter and Journal of Physics: Conference Series) and CDs containing all Conference papers. It was decided during the joint meeting of both the International Advisory Board and International Program Committee that the next conference in the LAM series, LAM14, will be arranged by the groups of A Di Cicco, Camerino University, and T Scopigno, University Roma `La Sapienza', in Rome, Italy. It is not an easy task to comment on new scientific tendencies in the field of liquid and amorphous alloys just after the conference. It takes one or two years to estimate the significance of the event. Only one conclusion is obvious: the LAM13 Conference had opened a door between the world scientific community and Russian scientists who have high expertise in the field but could not actively participate in the conferences of the LAM series before because of the situation in Russian economics. We are thankful to the Advisory and Program Committees of previous LAM12 conference in Metz and especially to Dr Monique Calvo-Dahlborg for their trust and the opportunity to manage such an outstanding event in Russia. In addition we would like to give all our sincere thanks to:

  20. the authorities of the Russian Academy of Sciences, its Ural Branch and Ural State Pedagogical University who have done their best and who helped us with all problems, especially to Boris Igoshev and Nikolay Vatolin;
  21. all sponsors who supported the conference: Russian Foundation for Basic Research, Ural Mining and Metallurgical Company headed by Andrey Kozicyn, Open Joint Stock Company `Uralsvjazinform' (Alexey Ufimkin), A A Baikov Institute of Metallurgy and Materials Science RAS (July Kovneristii), Institute for Physics and Power Engineering (Alexandre Ephanov), Nuclear Power Plant `Beloyarskaya' (Nikolay Oshkanov), South Ural State University (German Vjatkin), Ural Technical Institute of Communications and Informatics (Evgeny Subbotin), Physical - Technical Institute UB RAS (Vladimir Lad'yanov), Metallurgical Department of the Ural State Technical University (Victor Shimov), Academy of Sciences of Chechen Republic (Raikom Dadashev) and NETZSCH-Gerätebau GmbH;
  22. the invited lecturers who have immediately answered positively to the invitation and contributed to the high level of LAM13;
  23. all the colleagues who have not hesitated to act as chairmen in the various sessions;
  24. Graham Douglas and Richard Palmer from IOP Publishing, who have kindly answered all our emails and found solutions to all our questions and demands;
  25. wise seniors of the LAM series who could not participate at the 13th conference but helped us to manage it in the best way, namely to J Dupuy, M Silbert, F Sommer, W C Pilgrim, W Freyland, K Lu, J Brmejo and F Hensel.
  26. We dedicate the LAM13 conference to the 80-year jubilee of Professor Nikolay Vatolin who is the leader of Russian investigations in the field of liquid and amorphous metals and who managed twelve(!) similar conferences in our country. One of us (PP) commemorates his father, Professor Stanislav Popel, who was a known specialist in high temperature capillarity and left us half a year before the event. Pjotr Popel, Boris Gelchinskii, Valeriy Sidorov, Leonid Son, Alexandre Sabirzjanov Ekaterinburg, January 14 2008

  27. EDITORIAL: Adaptive and active materials: Selected papers from the ASME 2011 Conference on Smart Materials, Adaptive Structures and Intelligent Systems (SMASIS 11) (Scottsdale, AZ, USA, 18-21 September 2011) Adaptive and active materials: Selected papers from the ASME 2011 Conference on Smart Materials, Adaptive Structures and Intelligent Systems (SMASIS 11) (Scottsdale, AZ, USA, 18-21 September 2011)

    NASA Astrophysics Data System (ADS)

    Brei, Diann

    2012-09-01

    The fourth annual meeting of the ASME/AIAA Smart Materials, Adaptive Structures and Intelligent Systems Conference (SMASIS) took place in sunny Scottsdale, Arizona. Each year we strive to grow and offer new experiences. This year we held a special Guest Symposium on Sustainability along with two focused topic tracks on energy harvesting and active composites to encourage cross-fertilization between these important fields and our community. This cross-disciplinary emphasis was reflected in keynote talks by Dr Wayne Brown, President and founder of Dynalloy, Inc., 'Cross-Discipline Sharing'; Dr Brad Allenby, Arizona State University, 'You Want the Future? You can't Handle the Future!'; and Professor Aditi Chattopadhyay, Arizona State University, 'A Multidisciplinary Approach to Structural Health Monitoring and Prognosis'. SMASIS continues to grow our community through both social and technical interchange. The conference location, the exotic Firesky Resort and Spa, exemplified the theme of our Guest Symposium on Sustainability, being the only Green Seal certified resort in Arizona, and highlighting four elements thought to represent all that exist: fire, water, earth and air. Several special events were held around this theme including the night at the oasis reception sponsored by General Motors, sustainability bingo, smart trivia and student networking lunches, and an Arizona pow-wow with a spectacular Indian hoop dance. Our student and young professional development continues to grow strong with best paper and hardware competitions, scavenger student outing and games night. We are very proud that our students and young professionals are always seeking out ways to give back to the community, including organizing outreach to local high school talent. We thank all of our sponsors who made these special events possible. We hope that these social events provided participants with the opportunity to expand their own personal community and broaden their horizons. Our ultimate goal was to provide a friendly, casual southwestern forum for the exchange of the 'hottest' ideas and latest results. Our sincere appreciation goes to all the presenters for choosing to share their very best work at this conference. SMASIS is divided into seven symposia which span basic research, applied technological design and development, and industrial and governmental integrated system and application demonstrations: SYMP 1 Multifunctional Materials; SYMP 2 Active Materials, Mechanics and Behavior; SYMP 3 Modeling, Simulation and Control; SYMP 4 Enabling Technologies and Integrated System Design; SYMP 5 Structural Health Monitoring/NDE; SYMP 6 Bio-inspired Smart Materials and Structures; and SYMP 7 Guest Symposium on Sustainability. In addition, the conference introduced a new student and young professional development symposium. Authors of papers in the materials area (symposia 1, 2 and 6) were invited to write a full journal article on their presentation topic for publication in this Special Issue of Smart Materials and Structures. This collection of papers demonstrates the exceptional quality and originality of the conference presentations. We appreciate their efforts in producing this collection of highly relevant articles on smart materials.

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