21 CFR 601.70 - Annual progress reports of postmarketing studies.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Annual progress reports of postmarketing studies... SERVICES (CONTINUED) BIOLOGICS LICENSING Postmarketing Studies § 601.70 Annual progress reports of postmarketing studies. (a) General requirements. This section applies to all required postmarketing studies (e.g...
21 CFR 601.70 - Annual progress reports of postmarketing studies.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Annual progress reports of postmarketing studies... SERVICES (CONTINUED) BIOLOGICS LICENSING Postmarketing Studies § 601.70 Annual progress reports of postmarketing studies. (a) General requirements. This section applies to all required postmarketing studies (e.g...
ERIC Educational Resources Information Center
Young, Harben Boutourline
This annual report of the Yale Project describes the progress made on the nutrition and growth study of Tunisian children from September 1, 1971 through August 31, 1972. The report details: (1) the progress in analysis of the cross-sectional study data, which was completed as of June 30, 1972, and (2) the development of the present longitudinal…
ERIC Educational Resources Information Center
Brown, Daniel W.; And Others
This document comprises three progress reports for a 5-year environmental aging study aimed at establishing the lifetimes of magnetic tapes and the poly(ethylene terephthalate) (PET) base of photographic and electronic film under archival storage conditions. The first annual report (1982) introduces the rationale for the project, provides…
Hydrogen System Component Validation | Hydrogen and Fuel Cells | NREL
Meeting (June 2017) Hydrogen Component Validation: 2016 Annual Progress Report, Danny Terlip, Excerpt from the 2016 DOE Annual Progress Report (February 2017) Hydrogen Component Validation: 2016 Annual Merit Transportation Decisions, NREL Fact Sheet (June 2016) Hydrogen Component Validation: 2015 Annual Progress Report
ERIC Educational Resources Information Center
Florida Department of Education, 2014
2014-01-01
This Annual Measurable Objective (AMO) is designed to keep Florida moving forward toward national and international competitiveness. Florida will compare its National Assessment of Educational Progress (NAEP) scores to those of the top five states and its Trends in International Mathematics and Science Study (TIMSS), Progress in International…
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-03
... Information Collection: Comment Request; Annual Progress Reports for Empowerment Zones AGENCY: Office of... lists the following information: Title of proposal: Annual Progress Reports for Empowerment Zones. OMB... information collection for reporting requirements of 30 Urban Empowerment Zones (EZs). HUD will regularly...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1987-07-01
The U.S. Navy is conducting a long-term program to monitor for possible effects from the operation of its Extremely Low Frequency (ELF) Communications System to resident biota and their ecological relationships. This report documents progress of the following studies: Soil Amoeba; Soil and Litter Arthropoda and Earthworm Studies; Biological Studies on Pollinating insects: Megachilid Bees; and Small Vertebrates: Small Mammals and Nesting Birds.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1990-08-01
This is the eighth compilation of annual reports for the Navy's ELF Communications Systems Ecological Monitoring Program. The reports document the progress of eight studies performed during 1989 near the Naval Radio Transmitting Facility -- Republic, Michigan. The purpose of the monitoring is to determine whether electromagnetic fields produced by the ELF Communications System will affect resident biota or their ecological relationships. Soil Amoeba: Arthropoda and Earthworms: Pollinating Insects: Small Mammals and Nesting Birds.
45 CFR 1357.16 - Annual progress and services reports.
Code of Federal Regulations, 2011 CFR
2011-10-01
... wishes to include. (b) Submittal of the annual progress and services report and CFS-101. (1) The State and the Indian Tribe must send the Annual Progress and Services Report and the CFS-101 to the... allocations a CFS-101 must be submitted for each fiscal year. (3) States and Indian Tribes which have...
45 CFR 1357.16 - Annual progress and services reports.
Code of Federal Regulations, 2012 CFR
2012-10-01
... wishes to include. (b) Submittal of the annual progress and services report and CFS-101. (1) The State and the Indian Tribe must send the Annual Progress and Services Report and the CFS-101 to the... allocations a CFS-101 must be submitted for each fiscal year. (3) States and Indian Tribes which have...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-14
... of a Currently Approved Collection; Semi-Annual Progress Report for the Sexual Assault Services...-Annual Progress Report for Grantees from the Semi-Annual Progress Report for the Sexual Assault Services... assistance for adult, youth, and child victims of sexual assault, family and household members of victims...
1991-01-24
Molecular Graphics, vol. 6, No. 4 (Dec. 1988), p. 223. Turk, Greg, "Interactive Collision Detection for Molecular Graphics," M.S. thesis , UNC-Chapel Hill...Problem," Master’s thesis , UNC Department of Computer Science Technical Report #TR87-013, May 1987. Pique, ME., "Technical Trends in Molecular Graphics...AD-A236 598 Seventeenth Annual Progress Report and 1992-97 Renewal Proposal Interactive Graphics for Molecular Studies TR91-020 January 24, 1991 red
Leite, Andréa G B; Duarte, Maria Irma S; Mendes-Correa, Maria Cássia
2015-01-01
Several studies have demonstrated that HIV/hepatitis C virus (HCV)-coinfected patients experience more rapid fibrosis progression. In this study, to estimate the annual rate of direct liver fibrosis progression, we used analyses of paired biopsy samples from HIV/HCV-coinfected patients without prior treatment of hepatitis and assessed the possible association of fibrosis progression with certain clinical variables. We evaluated 30 HIV/HCV-coinfected patients, with no history of prior treatment of hepatitis C, who underwent paired liver biopsies. All patients were under antiretroviral therapy at first and second biopsies. The average annual progression rate was 0.13 fibrosis unit/year, with 36.7% of patients defined as progressors. Liver fibrosis progression was associated with alanine aminotransferase (ALT; P < .001) and aspartate aminotransferase (AST; P < .0340) levels over 3 times the upper limit of normal present at first biopsy. Elevated ALT and AST levels appear to be associated with more accelerated liver fibrosis progression among HIV/HCV-coinfected patients. © The Author(s) 2015.
Zhou, Wen-Jun; Zhang, Yong-Ye; Li, Hua; Wu, Yu-Fei; Xu, Ji; Lv, Sha; Li, Ge; Liu, Shi-Chun; Song, Sheng-Fang
2016-01-01
Background To determine the change in refractive error and the incidence of myopia among school-aged children in the Yongchuan District of Chongqing City, Western China. Methods A population-based cross-sectional survey was initially conducted in 2006 among 3070 children aged 6 to 15 years. A longitudinal follow-up study was then conducted 5 years later between November 2011 and March 2012. Refractive error was measured under cycloplegia with autorefraction. Age, sex, and baseline refractive error were evaluated as risk factors for progression of refractive error and incidence of myopia. Results Longitudinal data were available for 1858 children (60.5%). The cumulative mean change in refractive error was −2.21 (standard deviation [SD], 1.87) diopters (D) for the entire study population, with an annual progression of refraction in a myopic direction of −0.43 D. Myopic progression of refractive error was associated with younger age, female sex, and higher myopic or hyperopic refractive error at baseline. The cumulative incidence of myopia, defined as a spherical equivalent refractive error of −0.50 D or more, among initial emmetropes and hyperopes was 54.9% (95% confidence interval [CI], 45.2%–63.5%), with an annual incidence of 10.6% (95% CI, 8.7%–13.1%). Myopia was found more likely to happen in female and older children. Conclusions In Western China, both myopic progression and incidence of myopia were higher than those of children from most other locations in China and from the European Caucasian population. Compared with a previous study in China, there was a relative increase in annual myopia progression and annual myopia incidence, a finding which is consistent with the increasing trend on prevalence of myopia in China. PMID:26875599
Zhou, Wen-Jun; Zhang, Yong-Ye; Li, Hua; Wu, Yu-Fei; Xu, Ji; Lv, Sha; Li, Ge; Liu, Shi-Chun; Song, Sheng-Fang
2016-07-05
To determine the change in refractive error and the incidence of myopia among school-aged children in the Yongchuan District of Chongqing City, Western China. A population-based cross-sectional survey was initially conducted in 2006 among 3070 children aged 6 to 15 years. A longitudinal follow-up study was then conducted 5 years later between November 2011 and March 2012. Refractive error was measured under cycloplegia with autorefraction. Age, sex, and baseline refractive error were evaluated as risk factors for progression of refractive error and incidence of myopia. Longitudinal data were available for 1858 children (60.5%). The cumulative mean change in refractive error was -2.21 (standard deviation [SD], 1.87) diopters (D) for the entire study population, with an annual progression of refraction in a myopic direction of -0.43 D. Myopic progression of refractive error was associated with younger age, female sex, and higher myopic or hyperopic refractive error at baseline. The cumulative incidence of myopia, defined as a spherical equivalent refractive error of -0.50 D or more, among initial emmetropes and hyperopes was 54.9% (95% confidence interval [CI], 45.2%-63.5%), with an annual incidence of 10.6% (95% CI, 8.7%-13.1%). Myopia was found more likely to happen in female and older children. In Western China, both myopic progression and incidence of myopia were higher than those of children from most other locations in China and from the European Caucasian population. Compared with a previous study in China, there was a relative increase in annual myopia progression and annual myopia incidence, a finding which is consistent with the increasing trend on prevalence of myopia in China.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-01
... (Five Year Program). The Annual Progress Report is available for review at: www.boem.gov/Five-Year-Program-Annual-Progress-Report/ . Information on the Five Year Program is available online at http://www... final on August 27, 2012, after the required 60-day congressional review period. Section 18(e) of the...
Genetic progress in homogeneous regions of wheat cultivation in Rio Grande do Sul State, Brazil.
Follmann, D N; Cargnelutti Filho, A; Lúcio, A D; de Souza, V Q; Caraffa, M; Wartha, C A
2017-03-30
The State of Rio Grande do Sul (RS) stands out as the largest wheat producer in Brazil. Wheat is the most emphasized winter cereal in RS, attracting public and private investments directed to wheat genetic breeding. The study of genetic progress should be performed routinely at breeding programs to study the behavior of cultivars developed for homogeneous regions of cultivation. The objectives of this study were: 1) to evaluate the genetic progress of wheat grain yield in RS; 2) to evaluate the influence of cultivar competition trial stratification in homogeneous regions of cultivation on the study of genetic progress. Grain yield data of 122 wheat cultivars evaluated in 137 trials arranged in randomized block design with three or four replications were used. Field trials were carried out in 23 locations in RS divided into two homogeneous regions during the period from 2002 to 2013. Genetic progress for RS and homogeneous regions was studied utilizing the method proposed by Vencovsky. Annual genetic progress for wheat grain yield during the period of 12 years in the State of RS was 2.86%, oscillating between homogeneous regions of cultivation. The difference of annual genetic progress in region 1 (1.82%) in relation to region 2 (4.38%) justifies the study of genetic progress by homogeneous regions of cultivation.
Genetic progress in oat associated with fungicide use in Rio Grande do Sul, Brazil.
Follmann, D N; Cargnelutti Filho, A; Lúcio, A D; de Souza, V Q; Caraffa, M; Wartha, C A
2016-12-19
The State of Rio Grande do Sul (RS) is the largest producer of oat in Brazil with the aid of consolidated breeding programs, which are constantly releasing new cultivars. The main objectives of this study were to: 1) evaluate the annual genetic progress in grain yield and hectoliter weight of the oat cultivars in RS, with and without fungicide use on aerial parts of plants; and 2) evaluate the efficiency of oat breeding programs in introducing disease-resistant genes in the released cultivars through network yield trials conducted with and without fungicide use on aerial plant parts. The data on grain yield and hectoliter weight were obtained from 89 competition field trials of oat cultivars carried out from 2007 to 2014 in nine municipalities of RS. Of the total 89 trials, 44 were carried out with fungicide application on aerial plant parts and 45 were carried out without fungicide application. The annual genetic progress in oat cultivars was studied using the methodology proposed by Vencovsky (1988). The annual genetic progress in oat grain yield was 1.02% with fungicide use and 4.02% without fungicide use during the eight-year study period in RS. The annual genetic progress with respect to the hectoliter weight was 0.08% for trials with fungicide use and 0.71% for trials without fungicide use. Performing network yield trials with and without fungicide use on the aerial plants parts is a feasible method to evaluate the efficiency of oat breeding programs in introducing disease-resistant genes in the released cultivars.
Annual changes in radiographic indices of the spine in cerebral palsy patients.
Lee, Seung Yeol; Chung, Chin Youb; Lee, Kyoung Min; Kwon, Soon-Sun; Cho, Kyu-Jung; Park, Moon Seok
2016-03-01
We estimated the annual changes in radiographic indices of the spine in cerebral palsy (CP) patients and analyzed the factors that influence its progression rate. We included CP patients who had undergone whole-spine radiography more than twice and were followed for at least 1 year. The scoliosis Cobb angle, coronal balance, apical vertebral translation, apical rotation, and pelvic obliquity were measured on anteroposterior (AP) radiographs; thoracic kyphosis and lumbar lordosis angles, and sagittal balance was measured on lateral radiographs; and migration percentage was measured on AP hip radiographs to determine hip instability. For each gross motor function classification system (GMFCS) level, the Cobb angles, apical vertebral translation, coronal and sagittal balance, and pelvic obliquity were adjusted by multiple factors with a linear mixed model. A total of 184 patients (774 radiographs) were included in this study. There was no significant annual change in scoliosis Cobb, thoracic kyphosis, and lumbar lordosis angles in the GMFCS level I-II and III groups. In the GMFCS level IV-V group, there was an annual increase of 3.4° in the scoliosis Cobb angle (p = 0.020). The thoracic kyphosis angle increased by 2.2° (p = 0.018) annually in the GMFCS level IV-V group. Apical vertebral translation increased by 5.4 mm (p = 0.029) annually in the GMFCS level IV-V group. Progression of coronal and sagittal balance and pelvic obliquity with aging were not statistically significant. Sex, hip instability, hip surgery, and triradiate cartilage did not affect the progression of scoliosis and the balance of the spine and pelvis. The scoliosis Cobb angle, thoracic kyphosis angle, and apical vertebral translation in the GMFCS level IV-V CP patients progressed with age. These findings can predict radiographic progression of scoliosis in CP patients.
Influence of indoor and outdoor activities on progression of myopia during puberty.
Öner, Veysi; Bulut, Asker; Oruç, Yavuz; Özgür, Gökhan
2016-02-01
The purpose of this study was to investigate whether time spent on indoor and outdoor activities or the other possible risk factors including age, gender, parental history, and initial refraction was associated with progression of myopia, during puberty. Fifty eyes of 50 myopic children aged 9-14 years were enrolled in the study. The parents were interviewed to determine the amounts of time in hours per day spent on reading and writing, using computer, watching TV, and outdoor activities (i.e., sports, games, or being outdoor with no activities) on an average day. The annual myopia progression rate (diopters per year) was calculated for each subject and was used in the statistical analyses. The mean initial age of the subjects was 10.9 ± 1.5 (ranging from 9 to 14) years. The mean follow-up period was 33.3 ± 10.3 (ranging from 17 to 55) months. There was a significant increase in the mean myopia value of the subjects after follow-up period (p < 0.001). The mean daily time spent on reading and writing and initial refraction value were independently associated with annual myopic progression rate. On the other hand, age, gender, parental myopia, and the mean daily times spent on computer use, watching TV, and outdoor activities had no correlations with annual myopia progression rate. The present study showed that myopia progression was associated with time spent on reading and writing and initial refraction value, during puberty. However, myopia progression was not associated with parental myopia, age, gender, and daily times spent on using computer, watching TV, and outdoor activities.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Band, R.N.; Snider, R.J.; Snider, R.M.
1986-07-01
This volume consists of the following reports: Soil Amoeba; Soil and Litter Arthropoda and Earthworm Studies; Biological Studies on Pollinating Insects: Megachilid Bees; Small Vertebrates: Small Mammals and Nesting Birds.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-20
... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OPP-2012-0938; FRL-9374-7] Pesticide Reregistration Performance Measures and Goals; Annual Progress Report; Notice of Availability AGENCY: Environmental... EPA's progress report in meeting its performance measures and goals for pesticide reregistration...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-02
... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OPP-2011-0959; FRL-9343-5] Pesticide Reregistration Performance Measures and Goals; Annual Progress Report; Notice of Availability AGENCY: Environmental... EPA's progress report in meeting its performance measures and goals for pesticide reregistration...
Workforce Training and Economic Development Fund: 2015 Annual Progress Report
ERIC Educational Resources Information Center
Iowa Department of Education, 2015
2015-01-01
The Department of Education, Division of Community Colleges, will annually provide the State Board of Education with The Workforce Training and Economic Development (WTED) Fund Annual Progress Report. Administration and oversight responsibility for the fund was transferred from the Iowa Economic Development Authority to the Iowa Department of…
Clinical Investigation Program: Annual Progress Report
1992-09-30
Academy of Surgical Research, Chicago, Illinois; Yucatan Miniature Swine as a Model System for the Studyt of Vocal Fold Vibratory Function; 6th Annual...34(14)e". (15) Study Objective: Compare two enteral formulas in respect to nutritional aspects. (16) Technical Approach: Protocol will take place in
Longitudinal analysis of progression in glaucoma using spectral-domain optical coherence tomography.
Wessel, Julia M; Horn, Folkert K; Tornow, Ralf P; Schmid, Matthias; Mardin, Christian Y; Kruse, Friedrich E; Juenemann, Anselm G; Laemmer, Robert
2013-05-01
To compare the longitudinal loss of RNFL thickness measurements by SD-OCT in healthy individuals and glaucoma patients with or without progression concerning optic disc morphology. A total of 62 eyes, comprising 38 glaucomatous eyes with open angle glaucoma and 24 healthy controls, were included in the study (Erlangen Glaucoma Registry, NTC00494923). All patients were investigated annually over a period of 3 years by Spectralis SD-OCT measuring peripapillary RNFL thickness. By masked comparative analysis of photographs, the eyes were classified into nonprogressive and progressive glaucoma cases. Longitudinal loss of RNFL thickness was compared with morphological changes of optic disc morphology. Mixed model analysis of annual OCT scans revealed an estimated annual decrease of the RNFL thickness by 2.12 μm in glaucoma eyes with progression, whereas glaucoma eyes without progression in optic disc morphology lost 1.18 μm per year in RNFL thickness (P = 0.002). The rate of change in healthy eyes was 0.60 μm and thereby also significantly lower than in glaucoma eyes with progression (P < 0.001). The intrasession variability of three successive measurements without head repositioning was 1.5 ± 0.7 μm. The loss of mean RNFL thickness exceeded the intrasession variability in 60% of nonprogressive eyes, and in 85% of progressive eyes after 3 years. LONGITUDINAL MEASUREMENTS OF RNFL THICKNESS USING SD-OCT SHOW A MORE PRONOUNCED REDUCTION OF RNFL THICKNESS IN PATIENTS WITH PROGRESSION COMPARED WITH PATIENTS WITHOUT PROGRESSION IN GLAUCOMATOUS OPTIC DISC CHANGES. (www.clinicaltrials.gov number, NTC00494923.).
FY2011 Annual Progress Report for Propulsion Materials
DOE Office of Scientific and Technical Information (OSTI.GOV)
Davis, Patrick B.; Schutte, Carol L.; Gibbs, Jerry L.
Annual Progress Report for Propulsion Materials focusing on enabling and innovative materials technologies that are critical in improving the efficiency of advanced engines by providing enabling materials support for combustion, hybrid, and power electronics development.
Baseline predictors of aortic stiffness progression among multi-ethnic Asians with type 2 diabetes.
Moh, Mei Chung; Sum, Chee Fang; Tavintharan, Subramaniam; Ang, Keven; Lee, Simon Biing Ming; Tang, Wern Ee; Lim, Su Chi
2017-05-01
This 3-year prospective study aimed to identify baseline parameters that predicted the progression of carotid-femoral pulse wave velocity (cf-PWV), which was used to evaluate aortic stiffness, among Singapore's multi-ethnic Asians with type 2 diabetes (T2DM). The cf-PWV was measured by the gold-standard tonometry method in 994 T2DM subjects at baseline and follow-up. The annual rate of cf-PWV change was calculated, and individuals above the 90 th percentile with rate≥1.42 m/s per year were regarded as rapid progressors (n = 104). In a subgroup analysis of subjects with normal cf-PWV at 1 st visit (n = 611), incident aortic stiffness was defined as follow-up cf-PWV≥10 m/s (n = 188). The total cohort (mean age:57 ± 10 years; 53.4% Chinese, 20.4% Malay, 22.9% Indian, 3.2% 'Others') displayed a median annual cf-PWV progression rate of 0.2 m/s. Adjusted multivariate regression analyses showed that baseline age, cf-PWV and body mass index (BMI) constantly predicted follow-up cf-PWV, annual cf-PWV progression rate, rapid cf-PWV progression, and incident aortic stiffness. Paradoxically, lower baseline cf-PWV was associated with elevated annual cf-PWV progression rate and rapid progressors. This inverse relationship remained significant across ethnicities after ethnic stratification. Higher BMI independently predicted cf-PWV progression in Chinese and Indians, but not in Malay and 'Others' ethnic groups. Increased age was a significant predictor in Chinese and 'Others' ethnicities. We demonstrated that baseline BMI is a modifiable independent risk factor of cf-PWV progression and incident aortic stiffness. Therefore, better obesity management may impede aortic stiffness in Singapore's T2DM patients, especially in the Chinese and Indians. Copyright © 2017. Published by Elsevier B.V.
ERIC Educational Resources Information Center
Association of Research Libraries, Washington, DC. Office of Management Studies.
Designed to serve both as an activity report on Office of Management Studies (OMS) progress during 1987 and a catalog of OMS services and products, this annual report focuses on the management of technology in a scholarly environment. Programs and services are reported in five sections: (1) Applied Research and Development (the Institute on…
NASA Astrophysics Data System (ADS)
Suzuki, H.; Matsuhiro, M.; Kawata, Y.; Niki, N.; Nakano, Y.; Ohmatsu, H.; Kusumoto, M.; Tsuchida, T.; Eguchi, K.; Kaneko, Masahiro; Moriyama, N.
2014-03-01
Chronic obstructive pulmonary disease is a major public health problem that is predicted to be third leading cause of death in 2030. Although spirometry is traditionally used to quantify emphysema progression, it is difficult to detect the loss of pulmonary function by emphysema in early stage, and to assess the susceptibility to smoking. This study presents quantification method of smoking-induced emphysema progression based on annual changes of low attenuation volume (LAV) by each lung lobe acquired from low-dose CT images in lung cancer screening. The method consists of three steps. First, lung lobes are segmented using extracted interlobar fissures by enhancement filter based on fourdimensional curvature. Second, LAV of each lung lobe is segmented. Finally, smoking-induced emphysema progression is assessed by statistical analysis of the annual changes represented by linear regression of LAV percentage in each lung lobe. This method was applied to 140 participants in lung cancer CT screening for six years. The results showed that LAV progressions of nonsmokers, past smokers, and current smokers are different in terms of pack-year and smoking cessation duration. This study demonstrates effectiveness in diagnosis and prognosis of early emphysema in lung cancer CT screening.
A Multidisciplinary Approach to Study the Role of the Gut Microbiome in Relapsing and Progressive MS
2017-10-01
AWARD NUMBER: W81XWH-15-1-0654 TITLE: A Multidisciplinary Approach to Study the Role of the Gut Microbiome in Relapsing and Progressive MS...valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE Oct 2017 2. REPORT TYPE Annual 3. DATES COVERED 30...Multidisciplinary Approach to Study the Role of the Gut Microbiome in Relapsing and Progressive MS 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT
DOE Office of Scientific and Technical Information (OSTI.GOV)
Baalman, R.W.; Dotson, C.W.
1980-02-01
Part 5 of the 1979 Annual Report to the Department of Energy Assistant Secretary for the Environment presents Pacific Northwest Laboratory's progress on work performed for the Office of Technology Impacts, the Office of Environmental Compliance and Overview, and the Office of Health and Environmental Research. The report is in four sections, corresponding to the program elements: technology impacts, environmental control engineering, operational and environmental compliance, and human health studies. In each section, articles describe progress made during FY 1979 on individual projects.
Biology Division annual progress report for period ending December 31, 1968
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
1969-07-01
Brief summaries are presented of research in progress in the fields of radiobiology, genetics, hematology, immunology, physsiology, biochemistry, bacteriology, enzymology, microbiology, photosynthesis, biophysics, radiation protection, and related fields. A list is included of 212 publications in the world literature that report results of completed studies. (CH)
3 CFR - Improving Energy Security, American Competitiveness and Job Creation, and Environmental...
Code of Federal Regulations, 2011 CFR
2011-01-01
... source of fossil fuel consumption and greenhouse gas pollution. I therefore request that the... annual progress in reducing transportation sector emissions and fossil fuel consumption consistent with... substantial annual progress in reducing transportation sector greenhouse gas emissions and fossil fuel...
FY2014 Fuel & Lubricant Technologies Annual Progress Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Stork, Kevin
2016-02-01
Annual progress report for Fuel & Lubricant Technologies. The Fuel & Lubricant Technologies Program supports fuels and lubricants research and development (R&D) to provide vehicle manufacturers and users with cost-competitive options that enable high fuel economy with low emissions, and contribute to petroleum displacement.
76 FR 45234 - Information Collection; Submission for OMB Review, Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-28
... information collection request (ICR) entitled Annual Grantee Progress Report to the Office of Management and... through the use of appropriate automated, electronic, mechanical, or other technological collection... attached Annual Grantee Progress Report which will be used by grantees of the Corporation's AmeriCorps...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-10
... DEPARTMENT OF JUSTICE [OMB Number 1122-0006] Agency Information Collection Activities: Extension... Budget, Office of Information and Regulatory Affairs, Attention Department of Justice Desk Officer... hour to complete a semi-annual progress report. The semi-annual progress report is divided into...
The site designation for the Western and Central Long Island Sound disposal sites requires the completion of a Dredged Material Management Plan (DMMP) and EPA to conduct an annual review of progress toward completion of the DMMP.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-13
... of a Currently Approved Collection: Semi-Annual Progress Report for the Sexual Assault Services...-Annual Progress Report for Grantees from the Sexual Assault Services Program--Grants to Culturally... sustainable sexual assault services provided by culturally specific organizations, which are uniquely situated...
Southeastern Community College Annual Progress Report, December 1995.
ERIC Educational Resources Information Center
Gardner, R. Gene
Presenting information on the status of Southeastern Community College (SCC), in Iowa, this annual progress report highlights basic institutional data, financial information, and improvements and planned changes of the college as of 1995. Part 1 presents basic data on SCC, including facility locations, assessed property valuation, district…
Wraith, J E; Guffon, N; Rohrbach, M; Hwu, W L; Korenke, G C; Bembi, B; Luzy, C; Giorgino, R; Sedel, F
2009-11-01
Niemann-Pick disease type C (NP-C) is a devastating genetic disorder characterised by progressive neurological deterioration. However, data on the progression of neurological manifestations, particularly across different patient age-of-disease onsets, are limited. This is an observational retrospective cohort study designed to assess the progression of neurological disease in patients with NP-C. Physicians were asked to retrospectively complete a web-based questionnaire for each patient, at diagnosis and at up to three follow-up visits. An NP-C-specific disability scale was used to measure disease progression. The scale comprised four key parameters of neurological disease progression; ambulation, manipulation, language and swallowing. Disease progression was evaluated based on the annual rate of change in each parameter and the composite score using a linear mixed model analysis, and by classifying patients according to the number of worsened parameters during the observation period. Data were collected from 57 patients. The rate of deterioration was similar across the four individual parameters of the disability scale. The mean (95% CI) annual disease progression was +0.12 (0.09, 0.15) units. Among patients with a time interval of at least 1 year between diagnosis and last visit (n=49), 42 (86%) patients had progressed disease and 7 (14%) patients had stable disease. Disease progression was consistently more rapid in patients diagnosed in early childhood, compared with those diagnosed in late childhood, or with juvenile or adult presentation. In conclusion, our findings showed a progression in all four parameters of the disability scale, representing a continuous, unbroken progression of neurological manifestations.
Progress in Scientific and Technical Communications, 1968 Annual Report.
ERIC Educational Resources Information Center
Federal Council for Science and Technology, Washington, DC. Committee on Scientific and Technical Information.
This sixth annual report describes progress achieved by the Federal Government in improving the communication of scientific and technical information to support and enhance national science and technology. Included in the report are details regarding the scientific and technical activities of individual Federal Agencies, such as the Atomic Energy…
76 FR 11277 - Agency Information Collection Activities: Extension of a Currently Approved Collection
Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-01
...- Annual Progress Report for Grantees From the Grants To Support Tribal Domestic Violence and Sexual...-Annual Progress Report for Grantees from the Grants to Support Tribal Domestic Violence and Sexual... development and operation of new or existing nonprofit tribal domestic violence and sexual assault coalitions...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-24
... DEPARTMENT OF JUSTICE [OMB Number 1122-0024] Agency Information Collection Activities; Extension... Office of Management and Budget, Office of Information and Regulatory Affairs, Attention Department of...) approximately one hour to complete a semi-annual progress report. The semi-annual progress report is divided...
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... DEPARTMENT OF JUSTICE [OMB Number 1122-0022] Agency Information Collection Activities; Extension..., Attention Department of Justice Desk Officer, Washington, DC 20503. Additionally, comments may be submitted...) approximately one hour to complete a semi-annual progress report. The semi-annual progress report is divided...
2014 Annual Progress Report: DOE Hydrogen and Fuel Cells Program
DOE Office of Scientific and Technical Information (OSTI.GOV)
none,
2014-11-01
The 2014 Annual Progress Report summarizes fiscal year 2014 activities and accomplishments by projects funded by the DOE Hydrogen Program. It covers the program areas of hydrogen production and delivery; hydrogen storage; fuel cells; manufacturing; technology validation; safety, codes and standards; market transformation; and systems analysis.
Research on Automatic Classification, Indexing and Extracting. Annual Progress Report.
ERIC Educational Resources Information Center
Baker, F.T.; And Others
In order to contribute to the success of several studies for automatic classification, indexing and extracting currently in progress, as well as to further the theoretical and practical understanding of textual item distributions, the development of a frequency program capable of supplying these types of information was undertaken. The program…
NASA Technical Reports Server (NTRS)
Mccammon, Dan; Cox, D. P.; Kraushaar, W. L.; Sanders, W. T.
1990-01-01
The annual progress report on Cosmic X Ray Physics is presented. Topics studied include: the soft x ray background, proportional counter and filter calibrations, the new sounding rocket payload: X Ray Calorimeter, and theoretical studies.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kasten, P.R.; Coobs, J.H.; Lotts, A.L.
1976-04-01
Progress is summarized in studies relating to HTGR fuel reprocessing, refabrication, and recycle; HTGR fuel materials development and performance testing; HTGR PCRV development; HTGR materials investigations; HTGR fuel chemistry; HTGR safety studies; and GCFR irradiation experiments and steam generator modeling.
NASA Technical Reports Server (NTRS)
Mccammon, Dan; Cox, D. P.; Kraushaar, W. L.; Sanders, W. T.
1991-01-01
The annual progress report on Cosmic X Ray Physics for the period 1 Jan. to 31 Dec. 1990 is presented. Topics studied include: soft x ray background, new sounding rocket payload: x ray calorimeter, and theoretical studies.
DeLonay, Aaron J.; Jacobson, Robert B.; Papoulias, Diana M.; Wildhaber, Mark L.; Chojnacki, Kimberly A.; Pherigo, Emily K.; Haas, Justin D.; Mestl, Gerald E.
2012-01-01
The Comprehensive Sturgeon Research Project is a multiyear, multiagency collaborative research framework developed to provide information to support pallid sturgeon recovery and Missouri River management decisions. The project strategy integrates field and laboratory studies of sturgeon reproductive ecology, early life history, habitat requirements, and physiology. The project scope of work is developed annually with cooperating research partners and in collaboration with the U.S. Army Corps of Engineers, Missouri River Recovery—Integrated Science Program. The research consists of several interdependent and complementary tasks that engage multiple disciplines. The research tasks in the 2010 scope of work primarily address spawning as a probable factor limiting pallid sturgeon survival and recovery, although limited pilot studies also have been initiated to examine the requirements of early life stages. The research is designed to inform management decisions affecting channel re-engineering, flow modification, and pallid sturgeon population augmentation on the Missouri River, and throughout the range of the species. Research and progress made through this project are reported to the U.S. Army Corps of Engineers annually. This annual report details the research effort and progress made by the Comprehensive Sturgeon Research Project during 2010.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-01
... Collection; Semi- Annual Progress Report for Grantees from the Children and Youth Exposed to Violence Program... Violence Against Women (OVW) will be submitting the following information collection request to the Office... Violence Program. (3) Agency form number, if any, and the applicable component of the Department of Justice...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-25
... incidences of sexual assault, domestic violence, dating violence, or stalking. (5) An estimate of the total... collection Semi- Annual Progress Report for Grantees from the Children and Youth Exposed to Violence Program... Violence Against Women (OVW) will be submitting the following information collection request to the Office...
2015 Annual Progress Report: DOE Hydrogen and Fuel Cells Program
DOE Office of Scientific and Technical Information (OSTI.GOV)
None, None
The 2015 Annual Progress Report summarizes fiscal year 2015 activities and accomplishments by projects funded by the DOE Hydrogen and Fuel Cells Program. It covers the program areas of hydrogen production; hydrogen delivery; hydrogen storage; fuel cells; manufacturing R&D; technology validation; safety, codes and standards; systems analysis; and market transformation.
Building a Family Systems Model to Promote Adherence to PTSD Treatment
2015-10-01
stress disorder ( PTSD ) result in clinically significant symptom relief for many patients and are recommended as first-line treatments by the VA/DOD...findings at the annual meeting of the International Society of Traumatic Stress Studies (see citations below) and at an In Progress Review on 9/11...presentation at the 30th annual meeting of the International Society of Traumatic Stress Studies, Miami, Florida. ABSTRACT: We examined the role of family
Saxena, Rohit; Vashist, Praveen; Tandon, Radhika; Pandey, Ravindra M; Bhardawaj, Amit; Gupta, Vivek; Menon, Vimala
2017-01-01
To evaluate the incidence and progression of myopia and factors associated with progression of myopia in school going children in Delhi. Prospective longitudinal study of 10,000 school children aged 5 to 15 years screened after an interval of 1 year to identify new myopes (Spherical Equivalent≤ -0.5D) and progression of myopia in previously diagnosed myopic children. Association between risk factors and progression was analyzed using adjusted odds ratio. Of the 9,616 children re-screened (97.3% coverage), annual incidence of myopia was 3.4%with mean dioptric change of -1.09 ± 0.55. There was a significant higher incidence of myopia in younger children compared to older children (P = 0.012) and among girls compared to boys (P = 0.002). Progression was observed in 49.2%children with mean dioptric change of -0.27 ± 0.42 diopters. The demographic and behavioral risk factors were analyzed for children with progression (n = 629) and adjusted odds ratio values were estimated. Hours of reading-writing/week (p<0.001), use of computers/ video games (P<0.001) and watching television (P = 0.048) were significant risk factors for progression of myopia. Outdoor activities / time spent outdoors> 2 hours in a day were protective with an inverse association with progression of myopia (P< 0.001). Myopia is an important health issue in India and is associated with long hours of reading and screen time with use of computers and video games. An annual eye vision screening should be conducted, and outdoor activities be promoted to prevent the increase of myopia among school children.
Delonay, Aaron J.; Jacobson, Robert B.; Chojnacki, Kimberly A.; Braaten, Patrick J.; Buhl, Kevin J.; Eder, Brandon L; Elliott, Caroline M.; Erwin, Susannah O.; Fuller, David B.; Haddix, Tyler M.; Ladd, Hallie L.A.; Mestl, Gerald E.; Papoulias, Diana M.; Rhoten, Jason C.; Wesolek, Christopher J.; Wildhaber, Mark L.
2016-01-20
The research tasks in the 2013 scope of work emphasized understanding reproductive migrations and spawning of adult pallid sturgeon, and hatch and drift of free embryos and larvae. These tasks were addressed in four study sections located in three hydrologically and geomorphologically distinct parts of the Missouri River Basin: the Upper Missouri River downstream from Fort Peck Dam, including downstream reaches of the Milk River, the Lower Yellowstone River, and the Lower Missouri River downstream from Gavins Point Dam. The research is designed to inform management decisions related to channel re-engineering, flow modification, and pallid sturgeon population augmentation on the Missouri River, and throughout the range of the species. Research and progress made through this project are reported to the U.S. Army Corps of Engineers annually. This annual report details the research effort and progress made by the Comprehensive Sturgeon Research Project during 2013.
Vision for the Future of FIA: Paean to Progress, Possibilities, and Partners
Susan L. King; Charles T. Scott
2006-01-01
The Forest Inventory and Analysis (FIA) program of the U.S. Department of Agriculture Forest Service has made significant progress implementing the annualized inventory in 46 States in 2004. Major increases in program performance included the availability of plot data and the plots? corresponding approximate coordinates. A mill site study and biomass models were used...
2016 Annual Progress Report: DOE Hydrogen and Fuel Cells Program
DOE Office of Scientific and Technical Information (OSTI.GOV)
None, None
The 2016 Annual Progress Report summarizes fiscal year 2016 activities and accomplishments by projects funded by the DOE Hydrogen and Fuel Cells Program. It covers the program areas of hydrogen production; hydrogen delivery; hydrogen storage; fuel cells; manufacturing R&D; technology validation; safety, codes and standards; systems analysis; market transformation; and Small Business Innovation Research projects.
ERIC Educational Resources Information Center
Coastal Bend Migrant Council, Mathis, TX. San Patricio Migrant Health Center.
The annual medical progress report covers migrant health services in San Patricio County, Texas, from February 1, 1973 to January 31, 1974. The report discusses: staff, administration, cardiology, dental services, health services, medical services, outreach and environmental health services, prescription services, registration and identification,…
FLORIDA MIGRANT HEALTH PROJECT. FOURTH ANNUAL PROGRESS REPORT, 1966-1967.
ERIC Educational Resources Information Center
Florida State Board of Health, Jacksonville.
THE FOURTH ANNUAL PROGRESS REPORT OF THE FLORIDA MIGRANT HEALTH PROJECT INDICATES THAT IN 1966-67 THERE WAS AN APPRECIABLE INCREASE IN THE AMOUNT AND VARIETY OF MIGRANT HEALTH SERVICES RENDERED, THE NUMBER OF MIGRANTS CONTACTED, AND THE ACTIVITIES PERFORMED BY PROJECT PERSONNEL. MIGRANT HEALTH SERVICE REFERRALS INCREASED BY 1,222 OVER THE SAME…
Clinical Investigation Program Annual Progress Report
1988-10-20
Presented: Interna- tional Symposium on Orthopedics, Mexico , September 1987. Publications: In preparation. 147 FAMC A.P.R. (RCS MED 300) Detail Summary...Infection: A Prospective Study. Presented: 2nd Annual Symposium of the Rocky Moun- tain Flow Cytometry Users Group, Albuquerque, New Mexico , 10-11...Podgore, COL, MC (9) Dept/ISvc: Pediatrics (10) Associate Investigators (11) Key Words: Myron J. Levin, M.D. varicella vaccine U Co. HSC (12
DOE Office of Scientific and Technical Information (OSTI.GOV)
Coggin, J.H. Jr.
Progress is reported on the following research projects: evaluation of isotopic antiglobulin test (IAT) to detect tumor associated antigens using antisera induced by x-irradiated tumor cells; development of cytotoxic antibody for embryonic antigens (EA); acrylamide gel cell culture assay for transformation; and evaluation of 3-MCA induced sarcomas for TSTA and cross-reacting antigens. (HLW)
Synergistic Action of FOXP3 and TSC1 Pathways During Tumor Progression
2016-10-01
Tumor progression, Gene therapy, Transcriptional regulation, Post -translational modification ACCOMPLISHMENTS Our preliminary studies provide evidence...Annual PREPARED FOR: U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 DISTRIBUTION STATEMENT: Approved for...10. SPONSOR/MONITOR’S ACRONYM(S) U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 11. SPONSOR/MONITOR’S REPORT
Lu, Mingming; Peng, Peng; Cui, Yuanyuan; Qiao, Huiyu; Li, Dongye; Cai, Jianming; Zhao, Xihai
2018-03-01
This study aimed to investigate the association between carotid plaque progression and subsequent recurrent events using magnetic resonance imaging. Sixty-three symptomatic patients with ipsilateral carotid atherosclerotic stenosis (30%-69% stenosis) determined by ultrasound underwent first and second carotid artery magnetic resonance imaging for carotid artery at baseline and ≥6 months after the first scan, respectively. All the patients had clinical follow-up after the second magnetic resonance scan for ≤5 years until the onset of recurrent transient ischemic attack or stroke. Presence/absence of carotid plaque compositional features, particularly intraplaque hemorrhage and fibrous cap rupture was identified. The annual progression of carotid wall volume between 2 magnetic resonance scans was measured. Univariate and multivariate Cox regression was used to calculate the hazard ratio and corresponding 95% confidence interval of carotid plaque features in discriminating recurrent events. Receiver-operating-characteristic-curve analysis was conducted to determine the area-under-the-curve of carotid plaque features in predicting recurrent events. Sixty-three patients (mean age: 66.5±10.0 years old; 54 males) were eligible for final statistics analysis. During a mean follow-up duration of 55.1±13.6 months, 14.3% of patients (n=9) experienced ipsilateral recurrent transient ischemic attack/stroke. The annual progression of carotid wall volume was significantly associated with recurrent events before (hazard ratio, 1.14 per 10 mm 3 ; 95% confidence interval, 1.02-1.27; P =0.019) and after (hazard ratio, 1.19 per 10 mm3; 95% confidence interval, 1.03-1.37; P =0.022) adjusted for confounding factors. In discriminating the recurrence of transient ischemia attack/stroke, receiver-operator curve analysis indicated that combined with annual progression of wall volume, there was a significant incremental improvement in the area-under-the-curve of intraplaque hemorrhage (area-under-the-curve: 0.69-0.81) and fibrous cap rupture (area-under-the-curve: 0.73-0.84). The annual progression of carotid wall volume is independently associated with recurrent ischemic cerebrovascular events, and this measurement has added value for intraplaque hemorrhage and fibrous cap rupture in predicting future events. © 2018 American Heart Association, Inc.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 34 Education 2 2011-07-01 2010-07-01 true Statewide assessment; annual estimates; annual State goals and priorities; strategies; and progress reports. 361.29 Section 361.29 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE...
Code of Federal Regulations, 2010 CFR
2010-07-01
... 34 Education 2 2010-07-01 2010-07-01 false Statewide assessment; annual estimates; annual State goals and priorities; strategies; and progress reports. 361.29 Section 361.29 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE...
Adler, Amanda I; Stevens, Richard J; Manley, Sue E; Bilous, Rudy W; Cull, Carole A; Holman, Rury R
2003-01-01
The progression of nephropathy from diagnosis of type 2 diabetes has not been well described from a single population. This study sought to describe the development and progression through the stages of microalbuminuria, macroalbuminuria, persistently elevated plasma creatinine or renal replacement therapy (RRT), and death. Using observed and modeled data from 5097 subjects in the UK Prospective Diabetes Study, we measured the annual probability of transition from stage to stage (incidence), prevalence, cumulative incidence, ten-year survival, median duration per stage, and risk of death from all-causes or cardiovascular disease. From diagnosis of diabetes, progression to microalbuminuria occurred at 2.0% per year, from microalbuminuria to macroalbuminuria at 2.8% per year, and from macroalbuminuria to elevated plasma creatinine (>or=175 micromol/L) or renal replacement therapy at 2.3% per year. Ten years following diagnosis of diabetes, the prevalence of microalbuminuria was 24.9%, of macroalbuminuria was 5.3%, and of elevated plasma creatinine or RRT was 0.8%. Patients with elevated plasma creatinine or RRT had an annual death rate of 19.2% (95% confidence interval, CI, 14.0 to 24.4%). There was a trend for increasing risk of cardiovascular death with increasing nephropathy (P < 0.0001), with an annual rate of 0.7% for subjects in the stage of no nephropathy, 2.0% for those with microalbuminuria, 3.5% for those with macroalbuminuria, and 12.1% with elevated plasma creatinine or RRT. Individuals with macroalbuminuria were more likely to die in any year than to develop renal failure. The proportion of patients with type 2 diabetes who develop microalbuminuria is substantial with one quarter affected by 10 years from diagnosis. Relatively fewer patients develop macroalbuminuria, but in those who do, the death rate exceeds the rate of progression to worse nephropathy.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rondorf, Dennis W.; Miller, William H.
1993-07-01
This document is the 1991 annual progress report for selected studies of fall chinook salmon Oncorhynchus tshawytscha conducted by the US Fish and Wildlife Service. The decline in abundance of fall chinook salmon in the Snake River basin has become a growing concern. In April 1992, Snake River fall chinook salmon were listed as ``threatened`` under the Endangered Species Act. Effective recovery efforts for fall chinook salmon can not be developed until we increase our knowledge of the factors that are limiting the various life history stages. This study attempts to identify those physical and biological factors which influence spawningmore » of fall chinook salmon in the free-flowing Snake River and their rearing and seaward migration through Columbia River basin reservoirs.« less
Statewide Report Card: An Annual Report to the Legislature on Oregon Public Schools, 2013-2014
ERIC Educational Resources Information Center
Oregon Department of Education, 2014
2014-01-01
The Oregon Statewide Report Card is an annual publication required by law (ORS 329.115), which reports on the state of public schools and their progress towards the goals of the Oregon Educational Act for the 21st Century. The purpose of the Oregon Report Card is to monitor trends among school districts and Oregon's progress toward achieving the…
Statewide Report Card: An Annual Report to the Legislature on Oregon Public Schools, 2011-2012
ERIC Educational Resources Information Center
Oregon Department of Education, 2012
2012-01-01
The Oregon Statewide Report Card is an annual publication required by law (ORS 329.115), which reports on the state of public schools and their progress towards the goals of the Oregon Educational Act for the 21st Century. The purpose of the Oregon Report Card is to monitor trends among school districts and Oregon's progress toward achieving the…
Annual Progress Report - Fiscal Year 1982
1982-10-01
activity . A published method developed in our laboratory for determining tne antibacterial activity of mouse peritoneal phagocytes in vivo (1) has been...EDITOR’S NOTE This FY 1982 Annual Progress report is a general review of research activities of the U. S. Army Medical Research Institute of Infectious...years earlier. Passive immunization, active immunization using killed or living attenuated whole agent, or immunization with sub-unit antigens achieved
Statewide Report Card: An Annual Report to the Legislature on Oregon Public Schools; 2015-2016
ERIC Educational Resources Information Center
Oregon Department of Education, 2016
2016-01-01
The Oregon Statewide Report Card is an annual publication required by law (ORS 329.115), which reports on the state of public schools and their progress towards the goals of the Oregon Educational Act for the 21st Century. The purpose of the Oregon Report Card is to monitor trends among school districts and Oregon's progress toward achieving the…
Pathogenesis of Salmonellosis: Salmonella Exotoxins
1982-03-08
membrane-as3ociated enterotowin produced by S. enteritidis and by S. typhimurium ; however they could find no similarities between their Salmonella ...AD. . 0 REPORT NUJMBER 1 Pathogenesis of Salmoneiliosis: Salmonella Exotoxins Annual Progress Report (12/1/77-9/1/78) Johnny W. Peterson. Ph.D. March...TYPE OF REPORT & PERIOD COVEREOD",- Uathogenesis of ,Salmonellosils: Salmonella Annual Progress Report Exotoxins 12/T/77 9/1/78 C. PERFORMCNG ORG
ERIC Educational Resources Information Center
Oregon Department of Education, 2015
2015-01-01
The Oregon Statewide Report Card is an annual publication required by law (ORS 329.115), which reports on the state of public schools and their progress towards the goals of the Oregon Educational Act for the 21st Century. The purpose of the Oregon Report Card is to monitor trends among school districts and Oregon's progress toward achieving the…
76 FR 65184 - Proposed Information Collection; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-20
... Corporation is soliciting comments concerning its proposed Nonprofit Capacity Building Program Progress Report. The Progress Report consists of two parts: A Progress Report Narrative and a Performance Measurement Reporting Workbook. The Progress Report is completed semi-annually by Nonprofit Capacity Building Grantees...
DeLonay, Aaron J.; Jacobson, Robert B.; Papoulias, Diana M.; Wildhaber, Mark L.; Chojnacki, Kimberly A.; Pherigo, Emily K.; Bergthold, Casey L.; Mestl, Gerald E.
2010-01-01
The Comprehensive Sturgeon Research Project is a multiyear, multiagency collaborative research framework developed to provide information to support pallid sturgeon recovery and Missouri River management decisions. The general Comprehensive Sturgeon Research Project strategy is to integrate field and laboratory studies of sturgeon reproductive ecology, habitat requirements, and physiology to produce a predictive understanding of sturgeon population dynamics. The project scope of work is developed annually with cooperating research partners and in collaboration with the U.S. Army Corps of Engineers, Missouri River Recovery-Integrated Science Program. The research consists of several interdependent and complementary research tasks engaging multiple disciplines that primarily address spawning as a probable limiting factor in reproduction and survival of the pallid sturgeon. The research is multifaceted and is designed to provide information needed for management decisions impacting habitat restoration, flow modification, and pallid sturgeon population augmentation on the Missouri River, and throughout the range of the species. Research activities and progress towards understanding of the species are reported to the U.S. Army Corps of Engineers annually. This annual report details the research effort and progress made by Comprehensive Sturgeon Research Project during 2009.
ANALYTICAL CHEMISTRY DIVISION ANNUAL PROGRESS REPORT FOR PERIOD ENDING DECEMBER 31, 1961
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
1962-02-01
Research and development progress is reported on analytlcal instrumentation, dlssolver-solution analyses, special research problems, reactor projects analyses, x-ray and spectrochemical analyses, mass spectrometry, optical and electron microscopy, radiochemical analyses, nuclear analyses, inorganic preparations, organic preparations, ionic analyses, infrared spectral studies, anodization of sector coils for the Analog II Cyclotron, quality control, process analyses, and the Thermal Breeder Reactor Projects Analytical Chemistry Laboratory. (M.C.G.)
Mean annual attachment, bone level, and tooth loss: A systematic review.
Needleman, Ian; Garcia, Raul; Gkranias, Nikos; Kirkwood, Keith L; Kocher, Thomas; Iorio, Anna Di; Moreno, Federico; Petrie, Aviva
2018-06-01
Rate of progression of periodontitis has been used to inform the design of classifications of periodontal diseases. However, the evidence underpinning this topic is unclear and no systematic review has yet been conducted. The focused question for this systematic review was: in adults, what is the progression of periodontitis in terms of clinical attachment loss, radiographic bone loss, and tooth loss? Highly sensitive electronic search was conducted for published data in MEDLINE, EMBASE, LILACS, and unpublished grey literature in OpenGrey up to February 2016. Reference lists of retrieved studies for full-text screening and reviews were hand-searched for potentially eligible studies. Prospective, longitudinal observational studies with follow-up of at least 12 months and presenting data on the primary outcome, change in clinical attachment level, in adults (age ≥18 years). Secondary outcomes, tooth loss and bone level change, were only assessed in studies reporting the primary outcome. Studies investigating specific disease populations or only on treated periodontitis patients were excluded. Risk of bias and methodology were assessed using the Newcastle-Ottawa Scale with two additional questions on security of outcome assessment. Studies were pooled by abstracting or estimating mean annual attachment or bone level change and annual tooth loss. Random effects meta-analysis was conducted with investigation of effect of potential modifiers where possible. A total 11,482 records were screened for eligibility; 33 publications of 16 original studies reporting on more than 8,600 participants were finally included as eligible for the review. The studies represented populations from both developing and developed economies. Mean annual attachment loss was 0.1 mm per year (95% CI 0.068, 0.132; I 2 = 99%) and mean annual tooth loss was 0.2 teeth per year (95% CI 0.10, 0.33; I 2 = 94%). Observational analysis of highest and lowest mean attachment change quintiles suggested substantial differences between groups with minimal annual change in the lowest quintile and an average deterioration of 0.45 mm mean attachment loss per year in the highest group. This value increased to 0.6 mm per year with periodontitis alone. There was surprisingly little effect of age or gender on attachment level change. Geographic location, however, was associated with more than three times higher mean annual attachment loss in Sri Lanka and China (0.20 mm, 95% CI 0.15, 0.27; I 2 = 83%) vs North America and Europe (0.056 mm, 95% CI 0.025, 0.087; I 2 = 99%) P < 0.001. There were a limited number of studies (N = 16), high variability of design in key study components (sampling frames, included ages, data analyses), and high statistical heterogeneity that could not be explained. Within the limitations of the research, the data show that mean annual attachment level change varies considerably both within and between populations. Overall, the evidence does not support or refute the differentiation between forms of periodontal diseases based upon progression of attachment level change. © 2018 American Academy of Periodontology and European Federation of Periodontology.
Annual Research Progress Report, Fiscal Year 1988. Volume 2. (Brooke Army Medical Center)
1988-10-01
Phase III. (0) SWOG 8221 Treatment of Advanced Bladder Cancer with Preoperative Irradi- 362 ation and Radical Cystectomy vs. Radical Cystectomy Alone...Disease, Phase II. (0) POG 8731 Phase II Study of Low-dose "Continuous" Oral Methotrexate in 530 the Treatment of Children with Progressive or Recurrent...the other will receive a diet high in protein and carbohydrates but with minimal fiber. The remainder of the study will be conducted as outlined in the
2016 Nebraska Higher Education Progress Report
ERIC Educational Resources Information Center
Nebraska's Coordinating Commission for Postsecondary Education, 2016
2016-01-01
The 2016 Nebraska Higher Education Progress Report is the 12th annual progress report designed to provide the Nebraska Legislature with comparative statistics to monitor and evaluate progress toward achieving three key priorities for Nebraska's postsecondary education system. These priorities were developed by the 2003 LR 174 Higher Education Task…
ERIC Educational Resources Information Center
Texas Advisory Council for Technical - Vocational Education, Austin.
Assessment of the present status of vocational education in Texas and recommended priorities for the future constitute this annual report. Part 1 documents the progress of the 1970s and lists 15 challenges for vocational education in the 1980s, including application of meaningful evaluation procedures and careful program planning to maximize cost…
Annual Research Progress Report, Fiscal Year 1980
1980-10-01
AITE -sd Subtitle) 3. TYPE OF REPORT & PERIOD COVERED 4UAL RESEARCH pROGRESS REPORT ____________ANNUAL - FY 80 S- -- 4. PERFORMING ORG. REPORT NUNSER 7...AUHON) 4F e. CONTRACT OR GRANT NUMBER(e)’ JAMES DERSON, JR , M.D. 10. PERFORMING ORGANIZATION NAME AND ADDRESS 10- PROGRAM ELEMENT, PROJECT, TASK...and DOD) regulations governing human, animal and even in vitro research, the declining number of academic physicians serving as role models and
NASA Technical Reports Server (NTRS)
Spinks, Debra (Compiler)
1993-01-01
This report contains the 1992 annual progress reports of the Research Fellows and students of the Center for Turbulence Research. Considerable effort was focused on the large eddy simulation technique for computing turbulent flows. This increased activity has been inspired by the recent predictive successes of the dynamic subgrid scale modeling procedure which was introduced during the 1990 Summer Program. Several Research Fellows and students are presently engaged in both the development of subgrid scale models and their applications to complex flows. The first group of papers in this report contain the findings of these studies. They are followed by reports grouped in the general areas of modeling, turbulence physics, and turbulent reacting flows. The last contribution in this report outlines the progress made on the development of the CTR post-processing facility.
2018-05-15
This report summarizes the annual progress of EPA’s Clean Air Markets Programs such as the Acid Rain Program (ARP) and the Cross-State Air Pollution Rule (CSAPR). EPA systematically collects data on emissions, compliance, and environmental effects, these data are highlighted in our Progress Reports.
2018-05-16
This report summarizes the annual progress of EPA’s Clean Air Markets Programs such as the Acid Rain Program (ARP) and the Cross-State Air Pollution Rule (CSAPR). EPA systematically collects data on emissions, compliance, and environmental effects, these data are highlighted in our Progress Reports.
Dose-dependent progression of parkinsonism in manganese-exposed welders
Searles Nielsen, Susan; Criswell, Susan R.; Sheppard, Lianne; Seixas, Noah; Warden, Mark N.; Checkoway, Harvey
2017-01-01
Objective: To determine whether the parkinsonian phenotype prevalent in welders is progressive, and whether progression is related to degree of exposure to manganese (Mn)-containing welding fume. Methods: This was a trade union–based longitudinal cohort study of 886 American welding-exposed workers with 1,492 examinations by a movement disorders specialist, including 398 workers with 606 follow-up examinations up to 9.9 years after baseline. We performed linear mixed model regression with cumulative Mn exposure as the independent variable and annual change in Unified Parkinson Disease Rating Scale motor subsection part 3 (UPDRS3) as the primary outcome, and subcategories of the UPDRS3 as secondary outcomes. The primary exposure metric was cumulative Mn exposure in mg Mn/m3-year estimated from detailed work histories. Results: Progression of parkinsonism increased with cumulative Mn exposure. Specifically, we observed an annual change in UPDRS3 of 0.24 (95% confidence interval 0.10–0.38) for each mg Mn/m3-year of exposure. Exposure was most strongly associated with progression of upper limb bradykinesia, upper and lower limb rigidity, and impairment of speech and facial expression. The association between welding exposure and progression appeared particularly marked in welders who did flux core arc welding in a confined space or workers whose baseline examination was within 5 years of first welding exposure. Conclusions: Exposure to Mn-containing welding fume may cause a dose-dependent progression of parkinsonism, especially upper limb bradykinesia, limb rigidity, and impairment of speech and facial expression. PMID:28031394
Clinical Investigation Program Annual Progress Report.
1983-09-30
Antiemetics (A Phase II Study).(O) ............... 049 79/110 Evaluation of Local Anesthetic Skin Testing and Progressive Challenge in Patients with a History ...Associated with Oat Cell Carcinoma. J Assoc Mil Derm 8, 1982. Grimwood, R.E.: The History and Principles of Immunofluorescence. J Assn Mil Derm 9(1...December, 1981. ""’ PRESENTATIONS: 1.) Kindig, N.B.: D CO correction using PaCO back pressure predicted from venous bloo . Sfresented: Carl E
Health Transportation Working Group 2016 Annual Report
DOT National Transportation Integrated Search
2017-06-30
The Health in Transportation Working Group 2016 Annual Report provides an overview of the Working Groups activities and accomplishments in 2016, summarizes other USDOT health-related accomplishments, and documents its progress toward the recommend...
ERIC Educational Resources Information Center
Southern Rural Development Center, State College, MS.
Included in this second annual report on the Southern Rural Development Center's (SRDC) 1974-75 plan of work are data re: orientation visits; regional workshops; technical consultants; liaison with regional agencies and organizations; information dissemination; annual evaluation; functional networks in the areas of land use issues, citizen…
Fumery, Mathurin; Dulai, Parambir S; Gupta, Samir; Prokop, Larry J; Ramamoorthy, Sonia; Sandborn, William J; Singh, Siddharth
2017-05-01
Little is known about outcomes of patients with ulcerative colitis with low-grade dysplasia (UC-LGD). We estimated the incidence of and risk factors for progression to colorectal cancer (CRC) in cohorts of patients with UC-LGD who underwent surveillance (surveillance cohort), and the prevalence of dysplasia-related findings among patients who underwent colectomy for UC-LGD (surgical cohort). We performed a systematic literature review through June 1, 2016, to identify cohort studies of adults with UC-LGD. We estimated pooled incidence rates of CRC and risk factors associated with dysplasia progression in surveillance cohorts, and prevalence of synchronous advanced neoplasia (CRC and/or high-grade dysplasia) in surgical cohorts. In 14 surveillance cohort studies of 671 patients with UC-LGD (52 developed CRC), the pooled annual incidence of CRC was 0.8% (95% confidence interval [CI], 0.4-1.3); the pooled annual incidence of advanced neoplasia was 1.8% (95% CI, 0.9-2.7). Risk of CRC was higher when LGD was diagnosed by expert gastrointestinal pathologist (1.5%) than by community pathologists (0.2%). Factors significantly associated with dysplasia progression were concomitant primary sclerosing cholangitis (odds ratio [OR], 3.4; 95% CI, 1.5-7.8), invisible dysplasia (vs visible dysplasia; OR, 1.9; 95% CI, 1.0-3.4), distal location (vs proximal location; OR, 2.0; 95% CI, 1.1-3.7), and multifocal dysplasia (vs unifocal dysplasia; OR, 3.5; 95% CI, 1.5-8.5). In 12 surgical cohort studies of 450 patients who underwent colectomy for UC-LGD, 34 patients had synchronous CRC (pooled prevalence, 17%; 95% CI, 8-33). In a systematic review of the literature, we found that among patients with UC-LGD under surveillance, the annual incidence of progression to CRC was 0.8%; differences in rates of LGD diagnosis varied with pathologists' level of expertise. Concomitant primary sclerosing cholangitis, invisible dysplasia, distal location, and multifocal LGD are high-risk features associated with dysplasia progression. Copyright © 2017 AGA Institute. Published by Elsevier Inc. All rights reserved.
Hoffmann-Vold, Anna-Maria; Tennøe, Anders Heiervang; Garen, Torhild; Midtvedt, Øyvind; Abraityte, Aurelija; Aaløkken, Trond Mogens; Lund, May Britt; Brunborg, Cathrine; Aukrust, Pål; Ueland, Thor; Molberg, Øyvind
2016-08-01
Markers for early identification of progressive interstitial lung disease (ILD) in systemic sclerosis (SSc) are in demand. Chemokine CCL18, which has been linked to pulmonary inflammation, is an interesting candidate, but data have not been consistent. We aimed to assess CCL18 levels in a large, prospective, unselected SSc cohort with longitudinal, paired data sets on pulmonary function and lung fibrosis. Sera from the Oslo University Hospital SSc cohort (n = 298) and healthy control subjects (n = 100) were analyzed for CCL18 by enzyme immunoassay. High CCL18 (>53 ng/mL) was defined using the mean value plus 2 SD in sera obtained from healthy control subjects as the cutoff. High serum CCL18 was identified in 35% (105 of 298). Annual decline in FVC differed significantly between high and low CCL18 subsets (13.3% and 4.7%; P = .016), as did the annual progression rate of lung fibrosis (0.9% [SD, 2.9] and 0.2% [SD, 1.9]). Highest rates of annual FVC decline > 10% (21%) and annual fibrosis progression (1.2%) were seen in patients with high CCL18 and early disease (< 3 years). In multivariate analyses, CCL18 was associated with annual FVC decline > 10% (OR, 1.1; 95% CI, 1.01-1.11) and FVC < 70% at follow-up (OR, 3.1; 95% CI, 1.08-8.83). Survival analyses showed that patients with high CCL18 had reduced 5- and 10-year cumulative survival compared with patients with low CCL18 (85% and 74%, compared with 97% and 89%, respectively; P = .001). The results from this prospective cohort reinforce the notion that high CCL18 may serve as a marker for early identification of progressive ILD in SSc. Copyright © 2016 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.
Through its Annual Report to the Nation and other reports and publications, the National Cancer Institute – leader of the National Cancer Program – marks the progress that’s been made by the cancer research community.
34 CFR 200.50 - SEA review of LEA progress.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 34 Education 1 2010-07-01 2010-07-01 false SEA review of LEA progress. 200.50 Section 200.50... Basic Programs Operated by Local Educational Agencies Lea and School Improvement § 200.50 SEA review of LEA progress. (a) State review. (1) An SEA must annually review the progress of each LEA in its State...
34 CFR 200.50 - SEA review of LEA progress.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 34 Education 1 2012-07-01 2012-07-01 false SEA review of LEA progress. 200.50 Section 200.50... Basic Programs Operated by Local Educational Agencies Lea and School Improvement § 200.50 SEA review of LEA progress. (a) State review. (1) An SEA must annually review the progress of each LEA in its State...
34 CFR 200.50 - SEA review of LEA progress.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 34 Education 1 2013-07-01 2013-07-01 false SEA review of LEA progress. 200.50 Section 200.50... Basic Programs Operated by Local Educational Agencies Lea and School Improvement § 200.50 SEA review of LEA progress. (a) State review. (1) An SEA must annually review the progress of each LEA in its State...
34 CFR 200.50 - SEA review of LEA progress.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 34 Education 1 2014-07-01 2014-07-01 false SEA review of LEA progress. 200.50 Section 200.50... Basic Programs Operated by Local Educational Agencies Lea and School Improvement § 200.50 SEA review of LEA progress. (a) State review. (1) An SEA must annually review the progress of each LEA in its State...
34 CFR 200.50 - SEA review of LEA progress.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 34 Education 1 2011-07-01 2011-07-01 false SEA review of LEA progress. 200.50 Section 200.50... Basic Programs Operated by Local Educational Agencies Lea and School Improvement § 200.50 SEA review of LEA progress. (a) State review. (1) An SEA must annually review the progress of each LEA in its State...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hinga, K.R.
Volume II of the sixth annual report describing the progress and evaluating the status of the Subseabed Disposal Program contains the appendices referred to in Volume I, Summary and Status. Because of the length of Volume II, it has been split into two parts for publication purposes. Part 1 contains Appendices A-Q; Part 2 contains Appendices R-MM. Separate abstracts have been prepared for each appendix for inclusion in the Energy Data Base.
ERIC Educational Resources Information Center
Office of Special Education and Rehabilitative Services, US Department of Education, 2014
2014-01-01
This is the 33rd Annual Report to Congress on the Implementation of the "Individuals with Disabilities Education Act," 2011. Section 664(d) of the "Individuals with Disabilities Education Act" ("IDEA"), as reauthorized in 2004, requires that the Department of Education report annually on the progress made toward the…
Health in Transportation Working Group 2015 Annual Report
DOT National Transportation Integrated Search
2016-06-30
The Health in Transportation Working Group 2015 Annual Report provides an overview of the Working Groups activities and accomplishments : in 2015, summarizes other U.S. DOT health-related accomplishments, and documents its progress toward the reco...
De Stefano, Nicola; Giorgio, Antonio; Battaglini, Marco; De Leucio, Alessandro; Hicking, Christine; Dangond, Fernando; Giovannoni, Gavin; Sormani, Maria Pia
2018-02-01
Neuroimaging studies have used magnetic resonance imaging-derived methods to assess brain volume loss in multiple sclerosis (MS) as a reliable measure of diffuse tissue damage. In the CLARITY study ( ClinicalTrials.gov NCT00213135), the effect of 2 years' treatment with cladribine tablets on annualized percentage brain volume change (PBVC/y) was evaluated in patients with relapsing MS (RMS). Compared with placebo (-0.70% ± 0.79), PBVC/y was reduced in patients treated with cladribine tablets 3.5 mg/kg (-0.56% ± 0.68, p = 0.010) and 5.25 mg/kg (-0.57% ± 0.72, p = 0.019). After adjusting for treatment group, PBVC/y showed a significant correlation with the cumulative probability of disability progression (HR = 0.67, 95% CI = 0.571, 0.787; p < 0.001), with patients with lower PBVC/y showing the highest probability of remaining free from disability progression at 2 years and vice versa. Cladribine tablets given annually for 2 years in short-duration courses in patients with RMS in the CLARITY study significantly reduced brain atrophy in comparison with placebo treatment, with residual rates in treated patients being close to the physiological rates.
Laser program. Annual report, 1978
DOE Office of Scientific and Technical Information (OSTI.GOV)
Monsler, M.J.; Jarman, B.D.
1979-03-01
This volume documents progress in advanced quantum electronics - primarily the quest for advanced rep-rateable short-wavelength lasers with high efficiency. Application studies in electrical energy production and fissile fuel production are also described. Selected highlights of the advanced isotope separation program are also presented. (MOW)
Processes of arroyo filling in northern New Mexico, USA
Friedman, Jonathan M.; Vincent, Kirk R.; Griffin, Eleanor R.; Scott, Michael L.; Shafroth, Patrick B.; Auble, Gregor T.
2015-01-01
We documented arroyo evolution at the tree, trench, and arroyo scales along the lower Rio Puerco and Chaco Wash in northern New Mexico, USA. We excavated 29 buried living woody plants and used burial signatures in their annual rings to date stratigraphy in four trenches across the arroyos. Then, we reconstructed the history of arroyo evolution by combining trench data with arroyo-scale information from aerial imagery, light detection and ranging (LiDAR), longitudinal profiles, and repeat surveys of cross sections. Burial signatures in annual rings of salt cedar and willow dated sedimentary beds greater than 30 cm thick with annual precision. Along both arroyos, incision occurred until the 1930s in association with extreme high flows, and subsequent filling involved vegetation development, channel narrowing, increased sinuosity, and finally vertical aggradation. A strongly depositional sediment transport regime interacted with floodplain shrubs to produce a characteristic narrow, trapezoidal channel. The 55 km study reach along the Rio Puerco demonstrated upstream progression of arroyo widening and filling, but not of arroyo incision, channel narrowing, or floodplain vegetation development. We conclude that the occurrence of upstream progression within large basins like the Rio Puerco makes precise synchrony across basins impossible. Arroyo wall retreat is now mostly limited to locations where meanders impinge on the arroyo wall, forming hairpin bends, for which entry to and exit from the wall are stationary. Average annual sediment storage within the Rio Puerco study reach between 1955 and 2005 was 4.8 × 105 t/yr, 16% of the average annual suspended sediment yield, and 24% of the long-term bedrock denudation rate. At this rate, the arroyo would fill in 310 yr.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Reports. (a) States with Phase 1 projects shall submit semi-annual progress reports (original and one copy... in the next six months. (b) Phase 2. States with Phase 2 projects shall submit progress reports... Phase 2 project progress reports shall be determined by the size and complexity of the project, and...
Code of Federal Regulations, 2011 CFR
2011-07-01
... Reports. (a) States with Phase 1 projects shall submit semi-annual progress reports (original and one copy... in the next six months. (b) Phase 2. States with Phase 2 projects shall submit progress reports... Phase 2 project progress reports shall be determined by the size and complexity of the project, and...
Inhalation Toxicology Research Institute. Annual report, October 1, 1992--September 30, 1993
DOE Office of Scientific and Technical Information (OSTI.GOV)
Nikula, K.J.; Belinsky, S.A.; Bradley, P.L.
1993-11-01
This annual report for the Inhalation Toxicology Research Institute for 1992-1993 consists of 60 individual reports prepared separately by investigators describing progress in their own projects. Most papers are 2-5 pages long.
ERIC Educational Resources Information Center
Staumont, John
2017-01-01
Purpose: The purpose of this single-case study was to explore principals' perceptions of self-efficacy beliefs as effective instructional leaders during a period of educational transition in a semiurban, unified school district in Southern California. Methodology: The researcher used exploratory case study, conducting semistructured, open-ended,…
The National Research Council in 1977: Current Issues and Studies.
ERIC Educational Resources Information Center
National Academy of Sciences - National Research Council, Washington, DC.
This second annual report of the National Research Council (NRC) offers views of its officers on national issues from the vantage of the NRC, and descriptions of study projects in progress. Reports are made by the NRC's divisions of: behavioral and social sciences, life sciences, engineering, mathematical and physical sciences, international…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Drucker, H.
1981-02-01
Separate abstracts were prepared for 31 sections in this progress report. The appendix which deals with dose-effect studies with inhaled plutonium in beagles is not represented by a separate abstract. (KRM)
Chronic Disease and Perceived Developmental Progression in Adolescence.
ERIC Educational Resources Information Center
Seiffge-Krenke, Inge
1998-01-01
Examined whether chronic illness causes delays in adolescents' perceived developmental status, using annually-completed questionnaires from insulin-dependent and healthy adolescents. Found that, in first year of study, diabetic adolescents reported delays in physical maturity and an independent lifestyle compared with healthy peers. Overall…
Research 1970/1971: Annual Progress Report.
ERIC Educational Resources Information Center
Georgia Inst. of Tech., Atlanta. Science Information Research Center.
The report presents a summary of science information research activities of the School of Information and Computer Science, Georgia Institute of Technology. Included are project reports on interrelated studies in science information, information processing and systems design, automata and systems theories, and semiotics and linguistics. Also…
Annual Progress in Child Psychiatry and Child Development.
ERIC Educational Resources Information Center
Chess, Stella, Ed.; Thomas, Alexander, Ed.
Selected studies of infant development concern biological rhythms, pattern preferences, sucking, and Negro-white comparisons. Sex, age, state, eye to eye contact, and human symbiosis are considered in mother-infant interaction. Included in pediatrics are child development and the relationship between pediatrics and psychiatry. Environmental…
ERIC Educational Resources Information Center
Office of Special Education and Rehabilitative Services, US Department of Education, 2011
2011-01-01
This is the 30th Annual Report to Congress on the Implementation of the Individuals with Disabilities Education Act, 2008. Section 664(d) of the Individuals with Disabilities Education Act (IDEA), as reauthorized in 2004, requires that the Department of Education report annually on the progress made toward the provision of a free appropriate…
Wakabayashi, Kana; Tsujino, Takeshi; Naito, Yoshiro; Ezumi, Akira; Lee-Kawabata, Masaaki; Nakao, Shinji; Goda, Akiko; Sakata, Yasushi; Yamamoto, Kazuhiro; Daimon, Takashi; Masuyama, Tohru
2011-05-01
It is almost unknown which demographic factors or medications affect the progression of aortic stenosis (AS) in Japanese patients with mild AS. We identified a total of 194 patients with native tricuspid valvular AS, defined as a continuous-wave Doppler determined peak aortic valve jet velocity of ≥ 2.0 m/s, in whom echo Doppler studies were repeated at an interim of at least 6 months. Annualized change in peak jet velocity was calculated, and effects of age, sex, diabetes mellitus, blood pressure, serum low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and triglyceride levels, and use of statins and antihypertensive agents on the progression of AS were retrospectively evaluated. Peak aortic valve jet velocity was 2.36 ± 0.79 m/s (mean ± SD) and annualized increase in peak aortic valve jet velocity was 0.17 ± 0.32 m/s/year for all the studied patients. The increase in peak aortic valve jet velocity was lower in patients taking angiotensin-converting enzyme inhibitors (ACE-Is) than in those not taking ACE-Is (0.04 ± 0.22 vs. 0.20 ± 0.32 m/s/year, P < 0.05). Such protective associations were not observed for other first-line antihypertensive agents and statins. Multiple linear regression analysis revealed that ACE-I treatment, decrease in left ventricular ejection fraction, and higher peak aortic valve jet velocity at the first echocardiogram were associated with slower progression of AS. Administration of ACE-Is was associated with the slow progression of mild AS in Japanese patients. Prospective study to assess this hypothesis is needed.
International Space Station Electrodynamic Tether Reboost Study
NASA Technical Reports Server (NTRS)
Johnson, L.; Herrmann, M.
1998-01-01
The International Space Station (ISS) will require periodic reboost due to atmospheric aerodynamic drag. This is nominally achieved through the use of thruster firings by the attached Progress M spacecraft. Many Progress flights to the ISS are required annually. Electrodynamic tethers provide an attractive alternative in that they can provide periodic reboost or continuous drag cancellation using no consumables, propellant, nor conventional propulsion elements. The system could also serve as an emergency backup reboost system used only in the event resupply and reboost are delayed for some reason.
Yoo, Dong Eun; Han, Seung Hyeok; Oh, Hyung Jung; Kim, Seung Jun; Shin, Dong Ho; Lee, Mi Jung; Yoo, Tae-Hyun; Kang, Shin-Wook; Choi, Kyu Hun
2012-07-01
This study aimed to elucidate whether stone removal by extracorporeal shock wave lithotripsy (ESWL) is associated with delayed chronic kidney disease (CKD) progression. We conducted a retrospective analysis of 131 nephrolithiasis patients with stage 3 and 4 CKD. We collected baseline clinical and laboratory data, kidney stone characteristics, and history of receiving ESWL. We classified study patients into two groups according to whether they underwent ESWL or not (Non-ESWL group vs. ESWL group). We initially compared annual estimated glomerular filtration rate (eGFR) changes of Non-ESWL group with those of ESWL group before undergoing ESWL. In the next step, we sought to compare annual eGFR changes in the same patients before and after ESWL. Finally, we compared annual eGFR changes between success and failure groups among patients undergoing ESWL. The mean age of the patients was 62 years and 72.5% were male. The mean observation period was 3.2 years. Non-ESWL group and ESWL group before undergoing ESWL showed similar annual eGFR changes (-1.75±6.5 vs. -1.63±7.2 mL/min/1.73 m²/year, p=0.425). However, eGFR declined slower after undergoing ESWL than before ESWL (annual eGFR changes, -0.29±6.1 vs. -1.63±7.2 mL/min/1.73 m²/year, p<0.05). In addition, among patients in ESWL group, eGFR declined faster in the failure group than in the success group (annual eGFR change, -1.01±4.7 vs. -0.05±5.2 mL/min/1.73 m²/year, p<0.05). Our results suggest that stone removal by ESWL is associated with delayed deterioration of renal function in CKD patients with nephrolithiasis.
NASA Technical Reports Server (NTRS)
1991-01-01
The 1990 annual progress reports of the Research Fellows and students of the Center for Turbulent Research (CTR) are included. It is intended primarily as a contractor report to NASA, Ames Research Center. In addition, numerous CTR Manuscript Reports were published last year. The purpose of the CTR Manuscript Series is to expedite the dissemination of research results by the CTR staff. The CTR is devoted to the fundamental study of turbulent flow; its objectives are to produce advances in physical understanding of turbulence, in turbulence modeling and simulation, and in turbulence control.
Academic status and progress of deaf and hard-of-hearing students in general education classrooms.
Antia, Shirin D; Jones, Patricia B; Reed, Susanne; Kreimeyer, Kathryn H
2009-01-01
The study participants were 197 deaf or hard-of-hearing students with mild to profound hearing loss who attended general education classes for 2 or more hours per day. We obtained scores on standardized achievement tests of math, reading, and language/writing, and standardized teacher's ratings of academic competence annually, for 5 years, together with other demographic and communication data. Results on standardized achievement tests indicated that, over the 5-year period, 63%-79% of students scored in the average or above-average range in math, 48%-68% in reading, and 55%-76% in language/writing. The standardized test scores for the group were, on average, half an SD below hearing norms. Average student progress in each subject area was consistent with or better than that made by the norm group of hearing students, and 79%-81% of students made one or more year's progress annually. Teachers rated 69%-81% of students as average or above average in academic competence over the 5 years. The teacher's ratings also indicated that 89% of students made average or above-average progress. Students' expressive and receptive communication, classroom participation, communication mode, and parental participation in school were significantly, but moderately, related to academic outcomes.
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
1979-10-01
The primary objective of this program is to develop and demonstrate an improved PWR fuel assembly design capable of batch average burnups of 45,000-50,000 MWd/mtU. To accomplish this, a number of technical areas must be investigated to verify acceptable extended-burnup fuel performance. This report is the first semi-annual progress report for the program, and it describes work performed during the July-December 1978 time period. Efforts during this period included the definition of a preliminary design for a high-burnup fuel rod, physics analyses of extended-burnup fuel cycles, studies of the physics characteristics of changes in fuel assembly metal-to-water ratios, and developmentmore » of a design concept for post-irradiation examination equipment to be utilized in examining high-burnup lead-test assemblies.« less
NASA Astrophysics Data System (ADS)
Suzuki, H.; Mizuguchi, R.; Matsuhiro, M.; Kawata, Y.; Niki, N.; Nakano, Y.; Ohmatsu, H.; Kusumoto, M.; Tsuchida, T.; Eguchi, K.; Kaneko, M.; Moriyama, N.
2015-03-01
Computed tomography has been used for assessing structural abnormalities associated with emphysema. It is important to develop a robust CT based imaging biomarker that would allow quantification of emphysema progression in early stage. This paper presents effect of smoking on emphysema progression using annual changes of low attenuation volume (LAV) by each lung lobe acquired from low-dose CT images in longitudinal screening for lung cancer. The percentage of LAV (LAV%) was measured after applying CT value threshold method and small noise reduction. Progression of emphysema was assessed by statistical analysis of the annual changes represented by linear regression of LAV%. This method was applied to 215 participants in lung cancer CT screening for five years (18 nonsmokers, 85 past smokers, and 112 current smokers). The results showed that LAV% is useful to classify current smokers with rapid progression of emphysema (0.2%/year, p<0.05). This paper demonstrates effectiveness of the proposed method in diagnosis and prognosis of early emphysema in CT screening for lung cancer.
1981-10-20
Jamming strategies. D W 3 k 4 2 i t-iew or I oev Be is o ~5e TU SS ia Y LA P 16CUTV10’:F-,n-zv fam o& nm.o ANNUAL PROGRESS REPORT for Office of Naval...7:ectrtcal Enineering and :ne j drtinateo lc.aqce ’_aboratory :nlersit )t :llinol$ It rbana-ChampaLgn -roana, Illinois ild~l Abstract La the...11 treat the related problems of -ioLsa ncortaincy. robust Winner filtering and minimax icace estima- n eac,, case :nere la Assumed to is sois
Speech Research Status Report, January-June 1992.
ERIC Educational Resources Information Center
Studdert-Kennedy, Michael, Ed.
One of a series of semi-annual reports, this publication contains 23 articles which report the status and progress of studies on the nature of speech, instruments for its investigation, and practical applications. Articles are as follows: "Phonological and Articulatory Characteristics of Spoken Language" (Carol A. Fowler);…
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
1959-02-01
This annual report of Brookhaven National Laboratory describes its program and activities for the fiscal year 1958. The progress and trends of the research program are presented along with a description of the operational, service, and administrative activities of the Laboratory. The scientific and technical details of the many research and development activities are covered more fully in scientific and technical periodicals and in the quarterly scientific progress reports and other scientiflc reports of the Laboratory. A list of all publications for July 1, 1957 to June 30, 1958, is given. Status and progress are given in fields of physics,more » accelerator development, instrumentation, applied mathematics, chemistry, nuclear engineering, biology, and medical research. (For preceding period see BNL-462.) (W.D.M.)« less
DeLonay, Aaron J.; Jacobson, Robert B.; Chojnacki, Kimberly A.; Annis, Mandy L.; Braaten, P. J.; Elliott, Caroline M.; Fuller, D. B.; Haas, Justin D.; Haddix, Tyler M.; Ladd, Hallie L.A.; McElroy, Brandon J.; Mestl, Gerald E.; Papoulias, Diana M.; Rhoten, Jason C.; Wildhaber, Mark L.
2014-01-01
The Comprehensive Sturgeon Research Project is a multiyear, multiagency collaborative research framework developed to provide information to support pallid sturgeon recovery and Missouri River management decisions. The project strategy integrates field and laboratory studies of sturgeon reproductive ecology, early life history, habitat requirements, and physiology. The project scope of work is developed annually with cooperating research partners and in collaboration with the U.S. Army Corps of Engineers, Missouri River Recovery—Integrated Science Program. The research consists of several interdependent and complementary tasks that engage multiple disciplines. The research tasks in the 2011 scope of work emphasized understanding of reproductive migrations and spawning of adult sturgeon, and hatch and drift of larvae. These tasks were addressed in three hydrologically and geomorphologically distinct parts of the Missouri River Basin: the Lower Missouri River downstream from Gavins Point Dam, the Upper Missouri River downstream from Fort Peck Dam and including downstream reaches of the Milk River, and the Lower Yellowstone River. The research is designed to inform management decisions related to channel re-engineering, flow modification, and pallid sturgeon population augmentation on the Missouri River, and throughout the range of the species. Research and progress made through this project are reported to the U.S. Army Corps of Engineers annually. This annual report details the research effort and progress made by the Comprehensive Sturgeon Research Project during 2011.
Delonay, Aaron J.; Chojnacki, Kimberly A.; Jacobson, Robert B.; Braaten, Patrick J.; Buhl, Kevin J.; Elliott, Caroline M.; Erwin, Susannah O.; Faulkner, Jacob D.A.; Candrl, James S.; Fuller, David B.; Backes, Kenneth M.; Haddix, Tyler M.; Rugg, Matthew L.; Wesolek, Christopher J.; Eder, Brandon L.; Mestl, Gerald E.
2016-03-16
The Comprehensive Sturgeon Research Project is a multiyear, multiagency collaborative research framework developed to provide information to support pallid sturgeon recovery and Missouri River management decisions. The project strategy integrates field and laboratory studies of sturgeon reproductive ecology, early life history, habitat requirements, and physiology. The project scope of work is developed annually with collaborating research partners and in cooperation with the U.S. Army Corps of Engineers, Missouri River Recovery Program–Integrated Science Program. The project research consists of several interdependent and complementary tasks that involve multiple disciplines.The project research tasks in the 2014 scope of work emphasized understanding of reproductive migrations and spawning of adult pallid sturgeon and hatch and drift of larvae. These tasks were addressed in three hydrologically and geomorphologically distinct parts of the Missouri River Basin: the Lower Missouri River downstream from Gavins Point Dam, the Upper Missouri River downstream from Fort Peck Dam and downstream reaches of the Milk River, and the Lower Yellowstone River. The project research is designed to inform management decisions related to channel re-engineering, flow modification, and pallid sturgeon population augmentation on the Missouri River and throughout the range of the species. Research and progress made through this project are reported to the U.S. Army Corps of Engineers annually. This annual report details the research effort and progress made by the Comprehensive Sturgeon Research Project during 2014.
Code of Federal Regulations, 2011 CFR
2011-04-01
... participated in the assessment. (b) Method B—Uniform Averaging Procedure. A school may use uniform averaging... 25 Indians 1 2011-04-01 2011-04-01 false If a school fails to achieve its annual measurable... Adequate Yearly Progress § 30.116 If a school fails to achieve its annual measurable objectives, what other...
Code of Federal Regulations, 2012 CFR
2012-04-01
... participated in the assessment. (b) Method B—Uniform Averaging Procedure. A school may use uniform averaging... 25 Indians 1 2012-04-01 2011-04-01 true If a school fails to achieve its annual measurable... Adequate Yearly Progress § 30.116 If a school fails to achieve its annual measurable objectives, what other...
Code of Federal Regulations, 2013 CFR
2013-04-01
... participated in the assessment. (b) Method B—Uniform Averaging Procedure. A school may use uniform averaging... 25 Indians 1 2013-04-01 2013-04-01 false If a school fails to achieve its annual measurable... Adequate Yearly Progress § 30.116 If a school fails to achieve its annual measurable objectives, what other...
Code of Federal Regulations, 2010 CFR
2010-04-01
... participated in the assessment. (b) Method B—Uniform Averaging Procedure. A school may use uniform averaging... 25 Indians 1 2010-04-01 2010-04-01 false If a school fails to achieve its annual measurable... Adequate Yearly Progress § 30.116 If a school fails to achieve its annual measurable objectives, what other...
Code of Federal Regulations, 2014 CFR
2014-04-01
... participated in the assessment. (b) Method B—Uniform Averaging Procedure. A school may use uniform averaging... 25 Indians 1 2014-04-01 2014-04-01 false If a school fails to achieve its annual measurable... Adequate Yearly Progress § 30.116 If a school fails to achieve its annual measurable objectives, what other...
ERIC Educational Resources Information Center
Office of Special Education and Rehabilitative Services, US Department of Education, 2014
2014-01-01
This is the 32nd Annual Report to Congress on the Implementation of the Individuals with Disabilities Education Act, 2010. Section 664(d) of the Individuals with Disabilities Education Act (IDEA) (P.L. 108-446), as reauthorized in 2004, requires that the Department of Education report annually on the progress made toward the provision of a free…
Applied Meteorology Unit (AMU)
NASA Technical Reports Server (NTRS)
Bauman, William; Crawford, Winifred; Barrett, Joe; Watson, Leela; Wheeler, Mark
2010-01-01
The AMU has been in operation since September 1991. Tasking is determined annually with reviews at least semi-annually. The progress being made in each task is discussed in this report with the primary AMU point of contact reflected at the end of each task summary.
NASA Technical Reports Server (NTRS)
1996-01-01
This report contains the 1996 annual progress reports of the research fellows and students supported by the Center for Turbulence Research. Last year, CTR hosted twelve resident Postdoctoral Fellows, three Research Associates, four Senior Research Fellows, and supported one doctoral student and ten short term visitors.
DOT National Transportation Integrated Search
2003-05-15
This Annual Report provides an overview of the Intelligent Vehicle Initiatives (IVIs) progress and accomplishments during 2002. The 1998 Transportation Efficiency Act for the 21st Century (TEA-21) authorized IVI as part of the Department of Tra...
Research for Progress in Education. Annual Report: Fiscal Year 1970.
ERIC Educational Resources Information Center
National Center for Educational Research and Development (DHEW/OE), Washington, DC.
This annual report begins with a brief overview of cooperative research objectives and background. The five major sections are 1) "Cooperative Research Authorization" including the basic authorizations and subsequent amendments; 2) "Management Policies and Procedures;" 3) "Definitions and Distinctions" covering major…
Gregory A. Reams; Ronald E. McRoberts; Paul C. van Deusen; [Editors
2001-01-01
Documents progress in developing techniques in remote sensing, statistics, information management, and analysis required for full implementation of the national Forest Inventory and Analysis programâs annual forest inventory system.
Cost of illness associated with Niemann-Pick disease type C in the UK.
Imrie, Jackie; Galani, Carmen; Gairy, Kerry; Lock, Kevin; Hunsche, Elke
2009-09-01
Niemann-Pick disease type C (NP-C) is a rare and devastating genetic disorder characterised by a range of progressive neurological symptoms, which imposes a burden on patients, family members, the healthcare system and society overall. The objective of this study was to assess direct and indirect costs associated with NP-C in the UK. This was a non-interventional, retrospective, cross-sectional cohort study based on responses from patients and/or their carers/guardians recruited from a UK NP-C database. Resource use and direct medical, direct non-medical and indirect costs were evaluated using data collected via postal survey in October 2007, which included a Medical Resource Use questionnaire. Total annual costs per patient were estimated. In total, 18 Medical Resource Use questionnaires (29% response rate) were received and analysed. The mean total annual cost (SD) of NP-C per patient was 39,168 pounds (50,315 pounds); 46% were direct medical costs, to which home visits and residential care contributed 68% and 15%, respectively. Direct non-medical costs accounted for 24% of the average annual cost per patient, mainly due to specialist education, and indirect costs 30%. If only direct medical costs were considered, the mean annual cost (SD) per patient was reduced to 18,012 pounds (46,536 pounds). The direct annual per-patient cost of NP-C illness in 2007 appears moderate when compared with other rare and severely disabling diseases. However, cost estimates may be conservative, since findings are limited by a small sample size, low survey response rate and potential recall bias. As demonstrated by this study, a substantial proportion of the cost is shifted from the healthcare system to the patient, family and non-medical providers. These findings highlight the need for treatments that can slow or stop disease progression in NP-C.
Comparing Computer Adaptive and Curriculum-Based Measures of Math in Progress Monitoring
ERIC Educational Resources Information Center
Shapiro, Edward S.; Dennis, Minyi Shih; Fu, Qiong
2015-01-01
The purpose of the study was to compare the use of a Computer Adaptive Test and Curriculum-Based Measurement in the assessment of mathematics. This study also investigated the degree to which slope or rate of change predicted student outcomes on the annual state assessment of mathematics above and beyond scores of single point screening…
The 20th Annual Prostate Cancer Foundation Scientific Retreat report.
Miyahira, Andrea K; Simons, Jonathan W; Soule, Howard R
2014-06-01
The 20th Annual Prostate Cancer Foundation (PCF) Scientific Retreat was held from October 24 to 26, 2013, in National Harbor, Maryland. This event is held annually for the purpose of convening a diverse group of leading experimental and clinical researchers from academia, industry, and government to present and discuss critical and emerging topics relevant to prostate cancer (PCa) biology, and the diagnosis, prognosis, and treatment of PCa patients, with a focus on results that will lend to treatments for the most life-threatening stages of this disease. The themes that were highlighted at this year's event included: (i) mechanisms of PCa initiation and progression: cellular origins, neurons and neuroendocrine PCa, long non-coding RNAs, epigenetics, tumor cell metabolism, tumor-immune interactions, and novel molecular mechanisms; (ii) advancements in precision medicine strategies and predictive biomarkers of progression, survival, and drug sensitivities, including the analysis of circulating tumor cells and cell-free tumor DNA-new methods for liquid biopsies; (iii) new treatments including epigenomic therapy and immunotherapy, discovery of new treatment targets, and defining and targeting mechanisms of resistance to androgen-axis therapeutics; and (iv) new experimental and clinical epidemiology methods and techniques, including PCa population studies using patho-epidemiology. © 2014 Wiley Periodicals, Inc.
Speech Research, Status Report July-December 1991.
ERIC Educational Resources Information Center
Studdert-Kennedy, Michael, Ed.
One of a series of semi-annual reports, this publication contains 18 articles which report the status and progress of studies on the nature of speech, instruments for its investigation, and practical applications. Articles are as follows: "The Emergence of Native-Language Phonological Influences in Infants: A Perceptual Assimilation…
Speech Research Status Report, July-December 1992.
ERIC Educational Resources Information Center
Fowler, Carol A., Ed.
One of a series of semi-annual reports, this publication contains 25 articles which report the status and progress of studies on the nature of speech, instruments for its investigation, and practical applications. Articles are as follows: "Acoustic Shards, Perceptual Glue" (Robert E. Remez and Philip E. Rubin); "F0 Gives Voicing…
Laboratory directed research and development 2006 annual report.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Westrich, Henry Roger
2007-03-01
This report summarizes progress from the Laboratory Directed Research and Development (LDRD) program during fiscal year 2006. In addition to a programmatic and financial overview, the report includes progress reports from 430 individual R&D projects in 17 categories.
Maximizing the Prospects for Progress Against Cancer
The 2018 American Society of Clinical Oncology annual meeting featured numerous, potentially practice changing research findings, according to NCI Director Dr. Norman Sharpless. In this Cancer Currents post, Dr. Sharpless discusses the rapid pace of progress in cancer research.
Preparing for the Annual Audit.
ERIC Educational Resources Information Center
Nuehring, Bert
2002-01-01
Proposes several key questions that school district business officials should answer to prepare for an annual financial audit involving auditor information and resource needs, district and auditor monitoring and reporting on the audit progress, and reporting the results of the audit to the board of education. (PKP)
Topsakal, Vedat; Fransen, Erik; Schmerber, Sébastien; Declau, Frank; Yung, Matthew; Gordts, Frans; Van Camp, Guy; Van de Heyning, Paul
2006-09-01
To report the preoperative audiometric profile of surgically confirmed otosclerosis. Retrospective, multicenter study. Four tertiary referral centers. One thousand sixty-four surgically confirmed patients with otosclerosis. Therapeutic ear surgery for hearing improvement. Preoperative audiometric air conduction (AC) and bone conduction (BC) hearing thresholds were obtained retrospectively for 1064 patients with otosclerosis. A cross-sectional multiple linear regression analysis was performed on audiometric data of affected ears. Influences of age and sex were analyzed and age-related typical audiograms were created. Bone conduction thresholds were corrected for Carhart effect and presbyacusis; in addition, we tested to see if separate cochlear otosclerosis component existed. Corrected thresholds were than analyzed separately for progression of cochlear otosclerosis. The study population consisted of 35% men and 65% women (mean age, 44 yr). The mean pure-tone average at 0.5, 1, and 2 kHz was 57 dB hearing level. Multiple linear regression analysis showed significant progression for all measured AC and BC thresholds. The average annual threshold deterioration for AC was 0.45 dB/yr and the annual threshold deterioration for BC was 0.37 dB/yr. The average annual gap expansion was 0.08 dB/year. The corrected BC thresholds for Carhart effect and presbyacusis remained significantly different from zero, but only showed progression at 2 kHz. The preoperative audiological profile of otosclerosis is described. There is a significant sensorineural component in patients with otosclerosis planned for stapedotomy, which is worse than age-related hearing loss by itself. Deterioration rates of AC and BC thresholds have been reported, which can be helpful in clinical practice and might also guide the characterization of allegedly different phenotypes for familial and sporadic otosclerosis.
Utsumi, Yasuhiro; Sano, Yuzou; Funada, Ryo; Ohtani, Jun; Fujikawa, Seizo
2003-01-01
An analysis was made of progressive changes in patterns of cavitation in the sapwood of three species of conifer (Larix kaempferi, Abies sachalinensis, and Picea jezoensis) that were growing in a sub-frigid zone. In all three conifers, all tracheids of the newly forming outermost annual ring were filled with water or cytoplasm during the period from May to August. However, many tracheids in the transition zone from earlywood to latewood lost water in September, presumably through drought-induced cavitation. Cavitated tracheids tended to be continuously distributed in a tangential direction. Subsequently, some earlywood tracheids of the outermost annual ring lost water during the period from January to March. This was associated with freeze-thaw cycles. In the second and third annual rings from the cambium of all three conifers, the lumina of most tracheids in the transition zone from earlywood to latewood contained no water. In contrast, some latewood tracheids near the annual ring boundary and many earlywood tracheids retained water in their lumina. The third annual ring had more cavitated tracheids than the second annual ring. Our observations indicated that cavitation progressed gradually in the tracheids of the conifers and that they were never refilled once cavitation had occurred. The region involved in water transport in conifers did not include the entire sapwood and differed among annual rings. PMID:12692342
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-28
... to HUD based on the progress reported in implementing the EZs' strategic plans. Businesses located in... based on the progress reported in implementing the EZs' strategic plans. Businesses located in the EZs.... The primary purpose of this collection is to continue current data reporting for Rounds, I, II, and...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-18
... based on the progress reported in implementing the EZs' strategic plans. Businesses located in the EZs... based on the progress reported in implementing the EZs' strategic plans. Businesses located in the EZs... primary purpose of this collection is to continue current data reporting for Rounds, I, II, and III...
Bibliographical Work in New Zealand, 1980-1982. Work in Progress and Work Published.
ERIC Educational Resources Information Center
Millett, A. P. U., Comp.; Cole, F. T. H., Comp.
Formerly published as an irregular feature of New Zealand Libraries, these three annual bibliographies (1980, 1981, 1982) list bibliographical work in progress, as well as enumerative and subject bibliographies published in New Zealand from July 1977 to June 1982. It is noted that bibliographical work in progress is compiled from an annual…
Have the annual trends of total hip arthroplasty in rheumatoid arthritis patients decreased?
Onuoha, Kemjika O.; Solow, Max; Newman, Jared M.; Sodhi, Nipun; Pivec, Robert; Khlopas, Anton; Sultan, Assem A.; Chughtai, Morad; Shah, Neil V.; George, Jaiben
2017-01-01
Background Rheumatoid arthritis (RA) is characterized by chronic systemic and synovial inflammation, resulting in damage to both cartilage and bone. Medical treatment, which has increasingly relied upon disease modifying anti-rheumatic drugs (DMARDs), may fail to slow disease progression and limit joint damage, ultimately warranting surgical intervention. Up to 25% of RA patients will require lower extremity total joint arthroplasty. Though total hip arthroplasty (THA) is known to improve quality of life and functional measures, clarification is still required with respect to the impact of increased DMARD use on annual rates of THA. Thus, the purpose of this study was to evaluate: (I) the annual trends of THAs due to RA in the United States population; (II) the annual trends in the proportion of THAs due to RA in the United States. Methods This study utilized the Nationwide Inpatient Sample (NIS) to identify all patients who underwent THA between 2002 and 2013 (n=3,135,904). Then, THA patients who had a diagnosis of RA, which was defined by the International Classification of Disease 9th revision diagnosis code 714.0, were identified. The incidence of THAs with a diagnosis of RA in the United States was calculated using the United States population as the denominator. Regression models were used to analyze the annual trends of RA in patients who underwent THA. Results Review of the database identified 90,487 patients who had a diagnosis of RA and underwent THA from 2002 to 2013. The annual prevalence of RA in those who underwent THA slightly decreased over the specified time period, with 28.7 per 1,000 THAs in 2002 and 28.6 per 1,000 THAs in 2013; however, this change was not statistically significant (R2=0.158, P=0.200). Conclusions The annual rates of THA among RA patients did not show any significant change between 2002 and 2013. DMARD use has decreased both disease progression and joint destruction, and DMARDs are now often utilized as primary treatment. The increase in population of the country during the study period may have overestimated THA trends. Moreover, patients may be more likely to opt for surgical management, given the advances in operative techniques as well as peri- and post-operative course. PMID:29299482
Louisiana Believes: Annual Report 2013
ERIC Educational Resources Information Center
Louisiana Department of Education, 2013
2013-01-01
"Louisiana Believes" is the state's comprehensive plan to ensure every student is on track to a professional career or a college degree. This annual report details Louisiana's progress toward that objective during the 2012-2013 school year, along with strategy for the coming school year. "Louisiana Believes" has three…
77 FR 65903 - Agency Information Collection Activities: Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-31
... proposal; annual progress reports are required for awards of a two- to five-year duration. Final reports.../ . Responses are voluntary. No questions of a ``sensitive'' nature are asked. Affected Public: Research... benefits. Frequency of Collection: Annually: Grant proposals and reporting; Every two to five years...
Health physics division annual progress report for period ending June 30, 1977
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1978-07-01
This annual progress report follows, as in the past, the organizational structure of the Health Physics Division. Each part is a report of work done by a section of the division: Assessment and Technology Section (Part I), headed by H.W. Dickson; Biological and Radiation Physics Section (Part II), H.A. Wright; Chemical Physics and Spectroscopy Section (Part III), W.R. Garrett; Emergency Technology Section (Part IV), C.V. Chester, Medical Physics and Internal Dosimetry Section (Part V), K.E. Cowser; and the Analytic Dosimetry and Education Group (Part VI), J.E. Turner.
Annual Research Progress Report Letterman Army Institute of Research
1974-06-30
Nutritional studies have been conducted compariig the efficacy of 3 different diets (Study No. 2) Studies to establish precise Oj consumption and caloric ...Muscle Metabolism as Related to Exercise, Serum Electrolytes, Diet , and Steriods in Normal Man and Disease 81 065 The Effects of Nutrition and...Factors Influencing Physiological Functioning 105 168 The Effects of Diet Upon Respiration Metabolism 111 169 Comparative Pathology of Animals Maintained
DOE Office of Scientific and Technical Information (OSTI.GOV)
NONE
1994-03-01
This fourth annual report examines how well the World Bank`s environmental policies have worked during fiscal year 1993. It presents an agenda of actions that will help countries manage their environment better and link environmental protection with sustainable development. It describes ways to improve environmental impact studies of Bank-financed projects. The report notes the World Bank`s improved public communications network and increased cofinancing for environmental projects. The Bank`s work in implementing Global Environment Facility (GEF) policies and the Montreal Protocol is also reviewed.
Chemical and biological nonproliferation program. FY99 annual report
DOE Office of Scientific and Technical Information (OSTI.GOV)
NONE
2000-03-01
This document is the first of what will become an annual report documenting the progress made by the Chemical and Biological Nonproliferation Program (CBNP). It is intended to be a summary of the program's activities that will be of interest to both policy and technical audiences. This report and the annual CBNP Summer Review Meeting are important vehicles for communication with the broader chemical and biological defense and nonproliferation communities. The Chemical and Biological Nonproliferation Program Strategic Plan is also available and provides additional detail on the program's context and goals. The body of the report consists of an overviewmore » of the program's philosophy, goals and recent progress in the major program areas. In addition, an appendix is provided with more detailed project summaries that will be of interest to the technical community.« less
Koshurnikova, N N
2007-01-01
The biological production of the moss layer was analyzed in dark coniferous stands in progressive succession in the southern taiga in West Siberia. The rate of organic matter production by mosses changed from 15-22.2 g/(m2 y) in 50-90-year-old fir forests to 51.6 g/(m2 y) in 170-year-old mixed Siberian pine-spruce-fir stands. In forest phytocenosis that were formed with species replacement (after cuttings with understory clearing), the annual moss production (net primary production) ranged from 2.8 to 20.6 g/(m2 y). The annual moss cover production amounted to 35-36% of the moss photosynthetic biomass irrespective of the type of native stand progressive succession and the stand age.
Annual Progress Report FY-82. Volume II.
1982-01-01
subjective judgments, binaural amplification TITLE OF PROJECT: Subjective Comparisons of Binaural vs. Monaural Amplification PRINCIPAL INVESTIGATOR(S...REPORT STUDY OBJECTIVE: The purpose of this study is to determine (1) the consis- tency of subjective differences noted between binaural and monaural...candidates seen at WRAMC have been reviewed to determine rationale for preferences of mon- aural vs. binaural amplification. Comparisons are being made of
Annual Report, 1986. Southern Coalition for Educational Equity.
ERIC Educational Resources Information Center
David, Jane L.
This annual report summarizes the work and progress of programs which promote effective education in 11 Southern states. Working cooperatively with other groups, this advocacy organization has developed a model for putting effective schools research into practice. The Effective Schools Model has been accepted for use by the New Orleans Public…
FY 2012 Lightweight Materials Annual Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Warren, David C.
2013-04-15
The FY 2012 Annual Progress Report for Lightweight Materials provides a detailed description of the activities and technical accomplishments which focuses on the development and validation of advanced materials and manufacturing technologies to significantly reduce light and heavy duty vehicle weight without compromising other attributes such as safety, performance, recyclability, and cost.
ERIC Educational Resources Information Center
Southern Rural Development Center, State College, MS.
Covering the 1976 activities of the Southern Rural Development Center (SRDC), this third annual report describes SRDC's: history; organization; regional workshops; functional networks; network bibliographies and other publications; Title V reports; grant received for training in rural development; orientation visits; consultants; information…
Race to the Top - Early Learning Challenge: 2015 Annual Performance Report. Maryland
ERIC Educational Resources Information Center
Race to the Top - Early Learning Challenge, 2016
2016-01-01
This Race to the Top - Early Learning Challenge (RTT-ELC) annual performance report for the year 2015 describes Maryland's accomplishments, lessons learned, challenges, and strategies Maryland will implement to address those challenges. Maryland's remarkable progress in increasing participation in their tiered quality rating and improvement…
Race to the Top - Early Learning Challenge: 2015 Annual Performance Report. Vermont
ERIC Educational Resources Information Center
Race to the Top - Early Learning Challenge, 2016
2016-01-01
This Race to the Top - Early Learning Challenge (RTT-ELC) annual performance report for the year 2015 describes Vermont's accomplishments, lessons learned, challenges, and strategies Vermont will implement to address those challenges. Vermont's remarkable progress in increasing participation in their tiered quality rating and improvement system,…
Race to the Top - Early Learning Challenge: 2015 Annual Performance Report. Pennsylvania
ERIC Educational Resources Information Center
Race to the Top - Early Learning Challenge, 2016
2016-01-01
This Race to the Top - Early Learning Challenge (RTT-ELC) annual performance report for the year 2015 describes Pennsylvania's accomplishments, lessons learned, challenges, and strategies Pennsylvania will implement to address those challenges. Pennsylvania's remarkable progress in increasing participation in their tiered quality rating and…
Race to the Top - Early Learning Challenge: 2015 Annual Performance Report. Minnesota
ERIC Educational Resources Information Center
Race to the Top - Early Learning Challenge, 2016
2016-01-01
This Race to the Top - Early Learning Challenge (RTT-ELC) annual performance report for the year 2015 describes Minnesota's accomplishments, lessons learned, challenges, and strategies Minnesota will implement to address those challenges. Minnesota's remarkable progress in increasing participation in their tiered quality rating and improvement…
The World Fertility Survey: January 1976-December 1976. Annual Report.
ERIC Educational Resources Information Center
World Fertility Survey, London (England).
This annual report describes, through narrative and statistical tables, the progress made in 1976 by the World Fertility Survey (WFS), an international population research program. The function of the WFS is to assist a large number of interested countries, particularly the developing countries, in carrying out nationally representative,…
2017-01-01
The Annual Energy Outlook provides modeled projections of domestic energy markets through 2050, and includes cases with different assumptions of macroeconomic growth, world oil prices, technological progress, and energy policies. With strong domestic production and relatively flat demand, the United States becomes a net energy exporter over the projection period in most cases.
Arizona Adult Education Annual Performance Report. Fiscal Year 1993.
ERIC Educational Resources Information Center
Arizona State Dept. of Education, Phoenix. Div. of Adult Education.
This annual performance report on Arizona adult education begins with 3 pages of financial reports and statistical information presented in 9 tables and 19 charts. Tables and charts depict the following: participants by class type, age group, ethnic background, student progress, reason for separation before completion, and status; sites with…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-07
... DEPARTMENT OF JUSTICE [OMB Number 1122-0003] Agency Information Collection Activities: Extension of a Currently Approved Collection; Annual Progress Report for the STOP Formula Grants Program ACTION: 60-Day notice. The Department of Justice, Office on Violence Against Women (OVW) will be [[Page 66954
DOT National Transportation Integrated Search
2009-02-01
This annual report is a summary of the activities during 2007 for the Missouri Local Technical Assistance Program (Missouri LTAP), which is located at Missouri University of Science and Technology. The report highlights Missouri LTAPs performance ...
Environmental Sciences Division annual progress report for period ending September 30, 1983
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1984-04-01
This annual report summarizes activities in the Aquatic Ecology, Earth Sciences, Environmental Analyses, and Terrestrial Ecology sections, as well as in the Fossil Energy, Biomass, Low-Level Waste Research and Management, and Global Carbon Cycle Programs. Separate abstracts have been prepared for each section. (ACR)
Southern Rural Development Center Annual Progress Report, 1996.
ERIC Educational Resources Information Center
Southern Rural Development Center, Mississippi State, MS.
This annual report of the Southern Rural Development Center (SRDC) describes the agency's extension and research activities from October 1, 1995, to October 1, 1996. SRDC is one of four regional centers coordinating rural development research and extension education programs cooperatively with the land-grant institutions. SRDC cooperates with 29…
Microenvironmental Regulation of Mammary Carcinogenesis
2008-06-01
cells. These models share many of the hallmarks of multistage human breast cancer development including histological disease progression and immune cell... developed by Muller and colleagues20, represents a reasonable recapitulation of late-stage human breast cancer as determined by histological progression ...Annual Progress Report d. Develop a profile of proteolytic activities in normal and neoplastic mammary tissues from mouse models of mammary
Predicting Disease Progression in Scleroderma with Skin and Blood Biomarkers
2014-10-01
AWARD NUMBER: W81XWH-13-1-0452 TITLE: Predicting Disease Progression in Scleroderma with Skin...Annual 3. DATES COVERED 23Sep 2013 – 22 Sep 2014 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Predicting Disease Progression in...Scleroderma (Systemic Sclerosis, SSc) is a chronic, incurable autoimmune disease associated with high morbidity and mortality primarily due to SSc-lung
The Chip-Scale Atomic Clock - Recent Development Progress
2004-09-01
35th Annual Precise Time and Time Interval (PTTI) Meeting 467 THE CHIP-SCALE ATOMIC CLOCK – RECENT DEVELOPMENT PROGRESS R. Lutwak ...1] R. Lutwak , et al., 2003, “The Chip-Scale Atomic Clock – Coherent Population Trapping vs. Conventional Interrogation,” in
ERIC Educational Resources Information Center
Western Australia Science Education Association.
This proceedings contains the texts of 14 science education research studies which were presented at the 1983 Western Australia Science Education Conference. They include: "Students' Understanding of Chemical Equilibrium: A Report of Research in Progress" (Patrick J. Garnett, Mark W. Hackling); "Measuring the Learning Environment in…
Progress in Human Nutrition, Volume 1.
ERIC Educational Resources Information Center
Margen, Sheldon, Ed.
In view of the international character of nutrition and interrelationships and meaning of food to all people, this annual series of open-ended books has been started to direct attention to the aspects of human nutrition in regard to the quality of life. It is believed the study of the action nutrients, their interrelationships, and their ingestion…
Assessment Program Technical Progress Report, 1996-1997.
ERIC Educational Resources Information Center
McCown, Laurie; Fanning, Erin; Eickmeyer, Barbara
Coconino Community College (CCC) annually assesses its institutional effectiveness to demonstrate its commitment to improving programs and services to students. The 1996-97 Assessment Program Technical Progress Report records the assessment and institutional activities enacted during the academic year, detailing the assessment model, timelines,…
FY2013 Progress Report for Fuel & Lubricant Technologies
DOE Office of Scientific and Technical Information (OSTI.GOV)
none,
2014-02-01
Annual progress report for Fuel & Lubricant Technologies. The Fuel & Lubricant Technologies Program supports fuels and lubricants research and development (R&D) to provide vehicle manufacturers and users with cost-competitive options that enable high fuel economy with low emissions, and contribute to petroleum displacement.
Bernhard, Felix P; Heinzel, Sebastian; Binder, Gerhard; Weber, Karin; Apel, Anja; Roeben, Benjamin; Deuschle, Christian; Maechtel, Mirjam; Heger, Tanja; Nussbaum, Susanne; Gasser, Thomas; Maetzler, Walter; Berg, Daniela
2016-01-01
Biomarkers indicating trait, progression and prediction of pathology and symptoms in Parkinson's disease (PD) often lack specificity or reliability. Investigating biomarker variance between individuals and over time and the effect of confounding factors is essential for the evaluation of biomarkers in PD, such as insulin-like growth factor 1 (IGF-1). IGF-1 serum levels were investigated in up to 8 biannual visits in 37 PD patients and 22 healthy controls (HC) in the longitudinal MODEP study. IGF-1 baseline levels and annual changes in IGF-1 were compared between PD patients and HC while accounting for baseline disease duration (19 early stage: ≤3.5 years; 18 moderate stage: >4 years), age, sex, body mass index (BMI) and common medical factors putatively modulating IGF-1. In addition, associations of baseline IGF-1 with annual changes of motor, cognitive and depressive symptoms and medication dose were investigated. PD patients in moderate (130±26 ng/mL; p = .004), but not early stages (115±19, p>.1), showed significantly increased baseline IGF-1 levels compared with HC (106±24 ng/mL; p = .017). Age had a significant negative correlation with IGF-1 levels in HC (r = -.47, p = .028) and no correlation in PD patients (r = -.06, p>.1). BMI was negatively correlated in the overall group (r = -.28, p = .034). The annual changes in IGF-1 did not differ significantly between groups and were not correlated with disease duration. Baseline IGF-1 levels were not associated with annual changes of clinical parameters. Elevated IGF-1 in serum might differentiate between patients in moderate PD stages and HC. However, the value of serum IGF-1 as a trait-, progression- and prediction marker in PD is limited as IGF-1 showed large inter- and intraindividual variability and may be modulated by several confounders.
Binder, Gerhard; Weber, Karin; Apel, Anja; Roeben, Benjamin; Deuschle, Christian; Maechtel, Mirjam; Heger, Tanja; Nussbaum, Susanne; Gasser, Thomas; Maetzler, Walter; Berg, Daniela
2016-01-01
Introduction Biomarkers indicating trait, progression and prediction of pathology and symptoms in Parkinson's disease (PD) often lack specificity or reliability. Investigating biomarker variance between individuals and over time and the effect of confounding factors is essential for the evaluation of biomarkers in PD, such as insulin-like growth factor 1 (IGF-1). Materials and Methods IGF-1 serum levels were investigated in up to 8 biannual visits in 37 PD patients and 22 healthy controls (HC) in the longitudinal MODEP study. IGF-1 baseline levels and annual changes in IGF-1 were compared between PD patients and HC while accounting for baseline disease duration (19 early stage: ≤3.5 years; 18 moderate stage: >4 years), age, sex, body mass index (BMI) and common medical factors putatively modulating IGF-1. In addition, associations of baseline IGF-1 with annual changes of motor, cognitive and depressive symptoms and medication dose were investigated. Results PD patients in moderate (130±26 ng/mL; p = .004), but not early stages (115±19, p>.1), showed significantly increased baseline IGF-1 levels compared with HC (106±24 ng/mL; p = .017). Age had a significant negative correlation with IGF-1 levels in HC (r = -.47, p = .028) and no correlation in PD patients (r = -.06, p>.1). BMI was negatively correlated in the overall group (r = -.28, p = .034). The annual changes in IGF-1 did not differ significantly between groups and were not correlated with disease duration. Baseline IGF-1 levels were not associated with annual changes of clinical parameters. Discussion Elevated IGF-1 in serum might differentiate between patients in moderate PD stages and HC. However, the value of serum IGF-1 as a trait-, progression- and prediction marker in PD is limited as IGF-1 showed large inter- and intraindividual variability and may be modulated by several confounders. PMID:26967642
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hawley, R.S.
This research focuses on two repair deficient mutations in Drosophila melanogaster, namely mei-9, mei-41. In addition, the authors propose to extend this study to include the mus-312 mutation. They expect these studies to provide substantial insights into both the molecular mechanisms of DNA repair in Drosophila and the role these genes play in normal biological processes.
ERIC Educational Resources Information Center
Mississippi Band of Choctaw Indians, Philadelphia.
Self-determination for the Choctaw tribal government and its people was reflected in the progress made in program development. Programs in effect during fiscal year (FY) 1973 covered the full range of economic and social needs of the Choctaw people. Designed to complement the progress achieved during FY 1972, the following four developmental…
75 FR 65296 - Notice of Public Information Collection Requirements Submitted to OMB for Review
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-22
.... SUPPLEMENTARY INFORMATION: OMB Number: OMB 0412-New. Form Number: AID 321-2. Title: Mentor Prot[eacute]g[eacute] Program--Annual Report. Type of Submission: New Information Collection. Purpose: The mentors are required to report on the progress made under each active Mentor-Prot[eacute]g[eacute] Agreement annually...
Utah System of Higher Education 2015-16 Annual Report
ERIC Educational Resources Information Center
Utah System of Higher Education, 2016
2016-01-01
This annual report describes Utah System of Higher Education's progress in the 2015-2016 academic year in the following areas: (1) Strategic plan; (2) Enrollment and completion; (3) Paying for college; (4) Funding higher education; (5) College preparation; (6) Concurrent enrollment and math; (7) Outreach and access; and (8) Industry and the…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-26
... therapeutic drugs and biologics. This meeting is intended to be an open forum for the timely discussion of... data and measuring the progress being made in designing and implementing innovative solutions. DATES.... Background This annual FDA/DIA statistics forum will establish a unique, open, international forum for...
Annual Survey of Colleges, 1986-1987. Summary Statistics.
ERIC Educational Resources Information Center
College Entrance Examination Board, New York, NY.
Results of the College Board's Annual Survey of Colleges for 1986-1987 are presented, based on responses from 3,093 two-year and four-year institutions. Data for 1985 and trends for 1980 and 1984 cover undergraduate enrollments, student progress, academic programs, degrees conferred, and student financial aid. While most of the tables present…
ERIC Educational Resources Information Center
Southern Rural Development Center, State College, MS.
The Southern Rural Development Center's (SRDC) first annual report documents its organizational structure and provides a point by point summary of accomplishments relative to the following goals: (1) Develop, plan, and inventory existing rural development research knowledge; (2) Inventory rural development research needs and priorities; (3)…
ERIC Educational Resources Information Center
Linder, William W.
Summarizing Southern Rural Development Center (SRDC) activities and achievements during the October 1976-September 1977 fiscal year, this fourth annual report indicates that SRDC has been able to support rural development programs at land-grant institutions through sponsorship of workshops; issuance of publications, bibliographies, and a quarterly…
76 FR 19099 - Submission for OMB Review; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-06
... Servicers Review (ASPR), and Annual Budget Expenses Request and Estimated Expenditures (CFS-101). OMB No... called the CFS-101. The APSR is a Yearly report that discusses progress made by a State, Territory or... plan period. The CFS-101 has three parts. Part I is an annual budget request for the upcoming fiscal...
Environmental Quality, the Sixth Annual Report of the Council on Environmental Quality.
ERIC Educational Resources Information Center
Council on Environmental Quality, Washington, DC.
This sixth annual report discusses the state of the environment and progress accomplished in meeting the goals and objectives established for an improved environment. Each of the seven chapters deals with an important environmental parameter. Chapter one is devoted to carcinogens in the environment. Chapter two presents perspectives on the…
Race to the Top - Early Learning Challenge: 2015 Annual Performance Report. New Jersey
ERIC Educational Resources Information Center
Race to the Top - Early Learning Challenge, 2016
2016-01-01
This Race to the Top - Early Learning Challenge (RTT-ELC) annual performance report for the year 2015 describes New Jersey's accomplishments, lessons learned, challenges, and strategies New Jersey will implement to address those challenges. New Jersey's remarkable progress in increasing participation in their tiered quality rating and improvement…
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-07
... DEPARTMENT OF JUSTICE [OMB Number 1122-0003] Agency Information Collection Activities: Extension of a Currently Approved Collection; Annual Progress Report for the STOP Formula Grants Program ACTION: 60-Day notice of information collection under review. The Department of Justice, Office on Violence Against Women (OVW) will be submitting the...
FY 2009 National Renewable Energy Laboratory (NREL) Annual Report: A Year of Energy Transformation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
2010-01-01
This FY2009 Annual Report surveys the National Renewable Energy Laboratory's (NREL) accomplishments in renewable energy and energy efficiency research and development, commercialization and deployment of technologies, and strategic energy analysis. It offers NREL's vision and progress in building a clean, sustainable research campus and reports on community involvement.
Invasion of the exotic grasses: Mapping their progression via satellite
Eric B. Peterson
2008-01-01
Several exotic annual grass species are invading the Intermountain West. After disturbances including wildfire, these grasses can form dense stands with fine fuels that then shorten fire intervals. Thus invasive annual grasses and wildfire form a positive feedback mechanism that threatens native ecosystems. Chief among these within Nevada are Bromus tectorum...
1985-10-01
heterotrophic carbon dioxide fixa- tion. An assay for T2 toxin using the yeast Cryptococcus luteolus was evaluated as a rapid screening device for toxic...Bioassay for Mycotoxins Using Cryptococcus luteolus with Tetrazolium Salts." Poster session at the American Soc. for Microbiol. Annual Meeting, March
12 CFR 705.6 - Community needs plan.
Code of Federal Regulations, 2010 CFR
2010-01-01
... union's board of directors will report on the progress of providing needed community services to the credit union members once a year, either at the annual meeting or in a written report sent to all members. The credit union will also submit the written report or a summary of the report given at the annual...
Annual Review of Psychology. Volume 22, 1971.
ERIC Educational Resources Information Center
Mussen, Paul H., Ed.; Rosenzweig, Mark R., Ed.
The Annual Review of Psychology is compiled to provide authoritative evaluation of progress in both the traditional and the new areas of psychology. The 1971 edition includes the following topics and authors: Basic Drives, by Frank W. Finger and Douglas G. Mook; Behavioral Genetics, by Gardner Lindzey and others; Audition, by David H. Raab;…
Office of Management Services 1989 Annual Report.
ERIC Educational Resources Information Center
Association of Research Libraries, Washington, DC. Office of Management Studies.
Designed to serve both as an activity report on Office of Management Services (OMS) progress during 1989 and a catalog of OMS services and products, this annual report focuses on the management of human and technical resources in a scholarly environment. Programs and services are reported in four sections: (1) Applied Research and Development (the…
FY 1999 Annual Self-Evaluation Report of the Pacific Northwest National Laboratory
DOE Office of Scientific and Technical Information (OSTI.GOV)
Randy R. LaBarge
1999-11-05
This is a report of the Pacific Northwest National Laboratory's (Pacific Northwest's) FY1999 Annual Self-Evaluation Report. This report summarizes our progress toward accomplishment of the critical outcomes, objectives, and performance indicators as delineated in the FY1999 Performance Evaluation & Fee Agreement. It also summarizes our analysis of the results of Pacific Northwest's Division and Directorate annual self-assessments, and the implementation of our key operational improvement initiatives. Together, these provide an indication of how well we have used our Integrated Assessment processes to identify and plan improvements for FY2000. As you review the report you will find areas of significantly positivemore » progress; you will also note areas where I believe the Laboratory could make improvements. Overall, however, I believe you will be quite pleased to note that we have maintained, or exceeded, the high standards of performance we have set for the Laboratory.« less
Associations of reading posture, gaze angle and reading distance with myopia and myopic progression.
Pärssinen, Olavi; Kauppinen, Markku
2016-12-01
To study the associations of habitual reading posture, gaze angle in reading and reading distance with myopia and changes in myopia among myopic children. A total of 240 myopic schoolchildren (mean age 10.9 years), with no previous spectacles, were recruited during 1983-1984 to a randomized 3-year clinical trial of bifocal treatment of myopia. Three annual examinations with subjective cycloplegic refraction were conducted for 237-238 subjects. A further examination was conducted at the mean age of 23.2 years for 178 subjects. Habitual reading posture was elicited by questionnaire at study outset. Reading distance was measured with a Clement Clark accommodometer and gaze angle with an angle scale at baseline and all three annual follow-ups. Height was measured by a school nurse. The connections between the variables were studied with the standard statistical methods. Higher myopia was connected with shorter reading distance among girls at follow-ups 2 and 3, but not at the other examinations. The correlation of spherical equivalent with height was non-significant at each follow-up. Myopic progression across the whole follow-up was highest among those who read sitting down at baseline (-3.58 ± 1.75 D) and lowest among those who read face up lying down (-2.35 ± 1.53 D) (p = 0.021). Reading with eyes at a more downward angle was slightly connected with greater myopic progression (r = -0.166, p = 0.028). Reading in a sitting posture at myopia onset predicted the greatest myopic progression to adulthood and reading face up on one's back the lowest. Reading with eyes on turned more downwards was slightly connected with greater myopic progression. © 2016 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.
Research on Speech Perception. Progress Report No. 13.
ERIC Educational Resources Information Center
Pisoni, David B.; And Others
Summarizing research activities in 1987, this is the thirteenth annual report of research on speech perception, analysis, synthesis, and recognition conducted in the Speech Research Laboratory of the Department of Psychology at Indiana University. The report includes extended manuscripts, short reports, progress reports, and information on…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wallace, J.M.; Panetta, R.L.; Estberg, J.
1993-06-15
A 35-year record of monthly mean zonal wind data for the equatorial stratosphere is represented in terms of a vector (radius and phase angle) in a two-dimensional phase space defined by the normalized expansion coefficients of the two leading empirical orthogonal functions (EOFs) of the vertical structure. The tip of the vector completes one nearly circular loop during each cycle of the quasi-biennial oscillation (QBO). Hence, its position and rate of progress along the orbit of the point provide a measure of the instantaneous amplitude and rate of phase progression of the QBO. Although the phase of the QBO bearsmore » little if any relation to calendar month, the rate of phase progression is strongly modulated by the first and second harmonics of the annual cycle, with a primary maximum in April/May, in agreement with previous studies based on the descent rates of easterly and westerly regimes. A simple linear prediction model is developed for the rate of phase progression, based on the phase of the QBO and the phase of the annual cycle. The model is capable of hindcasting the phase of the QBO to within a specified degree of accuracy approximately 50% longer than a default scheme based on the mean observed rate of phase progression of the QBO (1 cycle per 28.1 months). If the seasonal dependence is ignored, the prediction equation corresponds to the [open quotes]circle map,[close quotes] for which an extensive literature exists in dynamical systems theory. 17 refs., 14 figs., 2 tabs.« less
International VLBI Service for Geodesy and Astrometry 2005 Annual Report
NASA Technical Reports Server (NTRS)
Behrend, Dirk (Editor); Baver, Karen D. (Editor)
2006-01-01
This volume of reports is the 2005 Annual Report of the International VLBI Service for Geodesy and Astrometry (IVS). The individual reports were contributed by VLBI groups in the international geodetic and astrometric community who constitute the components of IVS. The 2005 Annual Report documents the work of these IVS components over the period January 1, 2005 through December 31, 2005. The reports document changes, activities, and progress of the IVS. The entire contents of this Annual Report also appear on the IVS Web site at http://ivscc.gsfc.nasa.gov/publications/ar2005.
International VLBI Service for Geodesy and Astrometry 2007 Annual Report
NASA Technical Reports Server (NTRS)
Behrend, D. (Editor); Baver, K. D. (Editor)
2008-01-01
This volume of reports is the 2007 Annual Report of the International VLBI Service for Geodesy and Astrometry (IVS). The individual reports were contributed by VLBI groups in the international geodetic and astrometric community who constitute the components of IVS. The 2007 Annual Report documents the work of these IVS components over the period January 1, 2007 through December 31, 2007. The reports document changes, activities, and progress of the IVS. The entire contents of this Annual Report also appear on the IVS Web site at http://ivscc.gsfc.nasa.gov/publications/ar2007.
International VLBI Service for Geodesy and Astrometry 2008 Annual Report
NASA Technical Reports Server (NTRS)
Behrend, Dirk; Baver, Karen D.
2009-01-01
This volume of reports is the 2008 Annual Report of the International VLBI Service for Geodesy and Astrometry (IVS). The individual reports were contributed by VLBI groups in the international geodetic and astrometric community who constitute the components of IVS. The 2008 Annual Report documents the work of these IVS components over the period January 1, 2008 through December 31, 2008. The reports document changes, activities, and progress of the IVS. The entire contents of this Annual Report also appear on the IVS Web site at http://ivscc.gsfc.nasa.gov/publications/ar2008.
International VLBI Service for Geodesy and Astrometry 2011 Annual Report
NASA Technical Reports Server (NTRS)
Baver, Karen D. (Editor); Behrend, Dirk
2012-01-01
This volume of reports is the 2011 Annual Report of the International VLBI Service for Geodesy and Astrometry (IVS). The individual reports were contributed by VLBI groups in the international geodetic and astrometric community who constitute the components of IVS. The 2011 Annual Report documents the work of these IVS components over the period January 1, 2011 through December 31, 2011. The reports document changes, activities, and progress of the IVS. The entire contents of this Annual Report also appear on the IVS Web site at http://ivscc.gsfc.nasa.gov/publications/ar2011.
LLE 2009 annual report, October 2008-September 2009
DOE Office of Scientific and Technical Information (OSTI.GOV)
none, none
2010-01-01
The fiscal year ending September 2009 (FY2009) concluded the second year of the third five-year renewal of Cooperative Agreement DE-FC52-08NA28302 with the U.S. Department of Energy (DOE). This annual report summarizes progress in inertial fusion research at the Laboratory for Laser Energetics (LLE) during the past fiscal year. It also reports on LLE’s progress on laboratory basic science research; laser, optical materials, and advanced technology development; operation of OMEGA and OMEGA EP for the National Laser Users’ Facility (NLUF), and other external users; and programs focusingon the education of high school, undergraduate, and graduate students during the year.
Mzayek, Fawaz; Madhivanan, Purnima; Khader, Yousuf; Maziak, Wasim
2016-01-01
Introduction: Little evidence regarding longitudinal predictors of cigarette smoking progression is available from developing countries. This study aimed to identify gender-specific individual and social predictors of cigarette smoking progression among a school-based sample of adolescents in Irbid, Jordan. Methods: A total of 1781 seventh graders (participation rate 95%) were enrolled and completed an annual self-administered questionnaire from 2008 through 2011. Students who reported “ever-smoking a cigarette” at baseline or in the subsequent follow-up but not being “heavy daily smokers” (>10 cigarettes per day) were eligible for this analysis (N = 669). Grouped-time survival analyses were used to identify predictors of cigarette smoking progression in boys and girls. Results: Among the study sample, 38.3% of students increased the frequency and /or amount of cigarette smoking during the 3 years of follow-up. Among individual factors, the urge to smoke in the morning predicted smoking progression for boys and girls. The independent predictors of cigarette smoking progression were friends’ smoking and attending public schools in boys, and siblings’ smoking in girls. Discussing the dangers of smoking with family members was protective for girls. Conclusion: Boys and girls progressed similarly in cigarette smoking once they initiated the habit. Progression among girls was solely family-related, while it was peer-related for boys. PMID:25957340
DOE Office of Scientific and Technical Information (OSTI.GOV)
Whicker, F.W.
1976-08-01
This report summarizes project activities during the period May 1, 1975 through July 31, 1976. The major study on the distribution and levels of Pu in major components of the terrestrial ecosystem at Rocky Flats was completed. Supportive studies on the ecology and pathology of small mammals and their role in Pu transport were essentially completed as well. Detailed studies on mule deer food habits, population dynamics, and movements at Rocky Flats are progressing. These studies are designed to measure the potential of mule deer in transporting Pu to uncontrolled areas. Alpha autoradiographic studies designed to measure Pu particle sizemore » and distribution and spatial patterns in soil were initiated. Field and greenhouse transport pathways from soil to vegetation are in progress and some early results reported. The status of studies on seasonal kinetics of Cs in a montane lake and stable lead geochemistry in an alpine lake watershed are also reported.« less
Department of Clinical Investigation: Annual Research Progress Report for Fiscal Year 1992. Volume 2
1993-01-01
graded hypotension (MAP lowered in 10 mm Hg increments range 90 mm - 30 mm Hg), and hypothermia to 30 C. To study the effects of the commonly used inhaled ...peptide-poly-L-lysine conjugates were added to trehalose dimycolate and monophosphoryl lipid A (immune adjuvants) in oil-in-water micelles to aid in
1992-01-01
hypothermia to 30 C. To study the effects of the commonly used inhaled anesthetic, 14 hogs were subjected to 1/4 MAC (minimum alveolar concentration...the tether sequence (residues 142-156) of rhodanese. In both cases, the peptide-poly-L-lysine conjugates were added to trehalose dimycolate and
75 FR 34705 - Information Collection; Submission for OMB Review, Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-18
... respond, including the use of appropriate automated, electronic, mechanical, or other technological... Progress Report was published in the Federal Register on March 12, 2010. This comment period ended on May... encouraged the Corporation to retain the current Progress Report submission schedule of semi-annually to help...
Understanding Your Adequate Yearly Progress (AYP), 2011-2012
ERIC Educational Resources Information Center
Missouri Department of Elementary and Secondary Education, 2011
2011-01-01
The "No Child Left Behind Act (NCLB) of 2001" requires all schools, districts/local education agencies (LEAs) and states to show that students are making Adequate Yearly Progress (AYP). NCLB requires states to establish targets in the following ways: (1) Annual Proficiency Target; (2) Attendance/Graduation Rates; and (3) Participation…
National Disability Policy: A Progress Report
ERIC Educational Resources Information Center
National Council on Disability, 2008
2008-01-01
This National Council on Disability (NCD) annual progress report to the President and Congress covers the period December 2005 through December 2006. The report is divided into 13 chapters, each dealing with a major area of public policy. These subject-specific chapters are preceded by an introductory Major Trends section that identifies…
Research on Speech Perception. Progress Report No. 4, January 1977-September 1978.
ERIC Educational Resources Information Center
Pisoni, David B.; And Others
Summarizing research activities from January 1977 to September 1978, this is the fourth annual report of research on speech processing conducted in the Department of Psychology at Indiana University. The report includes extended manuscripts, short reports, progress reports, and information on instrumentation developments and software support. The…
DOT National Transportation Integrated Search
2001-01-01
The following progress report is intended to highlight the significant activities of the Florida Transit Training Program and Florida Technical Assistant Program for the 2001 year. Activities of the Florida Statewide Transit Training Program are pres...
NASA Technical Reports Server (NTRS)
Spinks, Debra (Compiler)
1990-01-01
This report contains the 1989 annual progress reports of the Research Fellows of the Center for Turbulence Research. It is intended as a year end report to NASA, Ames Research Center which supports this group through core funding and by making available physical and intellectual resources. The Center for Turbulence Research is devoted to the fundamental study of turbulent flows; its objectives are to simulate advances in the physical understanding of turbulence, in turbulence modeling and simulation, and in turbulence control. The reports appearing in the following pages are grouped in the general areas of modeling, experimental research, theory, simulation and numerical methods, and compressible and reacting flows.
Genetic Analysis of Oncorhynchus Nerka : 1991 Annual Progress Report.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Brannon, E.L.; Setter, A.L.; Welsh, T.L.
1992-01-01
The 1990 project to develop DNA assessment techniques for the purpose of determining relationships among populations of Oncorhynchus nerka demonstrated differences that had potential for such application. The work was continued in 1991 with specific application of the techniques to develop DNA probes that could be used in separating populations of 0. nerka associated with the lakes in the upper Salmon River, principally those in Redfish Lake. Research included sockeye-kokanee life history studies that might add supporting evidence for assessing the degree of difference or similarity among populations in the lake systems. This report summarizes the annual activities under themore » work plan.« less
Fundamental Studies on MPD Thrusters.
1987-09-02
WSCLASSIFIED WMS-93-0633 F/0s 21/3 ML L4 0 ’i JJJJJQ252 / .3 NII1~~ 33 fjffJ~* e 3- 11111 111 v 11 qP v lP IP qP P IP IP8 UNCLASSIFIED FlC ILE COPy AD-A 190...DATE OF REPORT (YtadI Month Day) IS. PAGE. COUNTN ’Final Scientific Report -62~r .To e .,861 1987- Sept. 2 259 16SUPPLEMENTARY NOTATION 4% COSAII...two earlier annual progress reports, summarizes . progress made under grant AFOSR-83-0033. %S 20 UiST1MIBUTIONIAVAILABILITY Of ABSTRACT 21. ASTRAW ~~ e
Building America Systems Integration Research Annual Report. FY 2012
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gestwick, Michael
2013-05-01
This Building America FY2012 Annual Report includes an overview of the Building America Program activities and the work completed by the National Renewable Energy Laboratory and the Building America industry consortia (the Building America teams). The annual report summarizes major technical accomplishments and progress towards U.S. Department of Energy Building Technologies Program's multi-year goal of developing the systems innovations that enable risk-free, cost effective, reliable and durable efficiency solutions that reduce energy use by 30%-50% in both new and existing homes.
GSA committees: Progress through service the Annual Program Committee
Costa, J.E.
2007-01-01
The GSA's Annual Program Committee (APC) is directly responsible for the GSA's meeting and other responsibilities especially before the main event. It decides on the locations, the number and content of the technical sessions, annual membership surveys, hospitality for the guests, field trips and more. In addition, it pays significant attention to creative thinking about geoscience discoveries and directions as well as identify new and emerging areas of earth science. APC is also looking for new ideas, approaches and directions.
The CERAD Neuropsychologic Battery Total Score and the progression of Alzheimer disease.
Rossetti, Heidi C; Munro Cullum, C; Hynan, Linda S; Lacritz, Laura H
2010-01-01
To establish the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) neuropsychologic battery as a valid measure of cognitive progression in Alzheimer disease (AD) by deriving annualized CERAD Total Change Scores and corresponding confidence intervals in AD and controls from which to define clinically meaningful change. Subjects included 383 normal control (NC) and 655 AD subjects with serial data from the CERAD registry database. Annualized CERAD Total Change Scores were derived and Reliable Change Indexes (RCIs) calculated to establish statistically reliable change values. CERAD Change Scores were compared with annualized change scores from the Mini-Mental State Examination (MMSE), Clinical Dementia Rating Scale (CDR) Sum of Boxes, and Blessed Dementia Rating Scale (BDRS). For the CERAD Total Score, the AD sample showed significantly greater decline than the NC sample over the 4-year interval, with AD subjects declining an average of 22.2 points compared with the NCs' improving an average 2.8 points from baseline to last visit [Group x Time interaction [F(4,1031)=246.08, P<0.001)]. By Visit 3, the majority of AD subjects (65.2%) showed a degree of cognitive decline that fell outside the RCI. CERAD Change Scores significantly correlated (P<0.001) with MMSE (r=-0.66), CDR (r=-0.42), and BDRS (r=-0.38) change scores. Results support the utility of the CERAD Total Score as a measure of AD progression and provide comparative data for annualized change in CERAD Total Score and other summary measures.
2014 Trans-Atlantic Research and Development Interchange ...
The Trans-Atlantic Research and Development Interchange on Sustainability (TARDIS) has been bringing together a select group of scientists and engineers for in-depth discussions on sustainability on a bi-annual basis since 2004. TARDIS 2014 included twenty eight individuals from across the globe discussing issues related to progress towards sustainability. The discussion included policies, technologies, societal structure and norms, business practices and culture, and time-frames. As discussed later, the focus was on four questions: (1) what progress has been accomplished in sustainability? (2) why has there not been more progress in moving societies towards sustainability? (3) what are the road-blocks to progress towards sustainability? (4) what are the policies, technologies, and other changes that are needed to make further progress towards sustainability? One salient conclusion from TARDIS 2014 is that while sustainability has entered mainstream thinking, significant social, economic, technological, and business barriers remain to further progress towards a sustainable path as discussed throughout this report. The Trans-Atlantic Research and Development Interchange on Sustainability is a bi-annual workshop alternatively held in the United States and Austria. The purpose is to bring the best thinkers from across the globe to discuss, explore, and clarify major issues related to sustainability. A report summarizing teh finding and discussions is prepared and d
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rondorf, Dennis W.; Miller, William H.
1994-03-01
This document is the 1992 annual progress report for selected studies of fall chinook Salmon Oncorhynchus tshawytscha conducted by the National Biological Survey (NBS) and the US Fish and Wildlife Service. The decline in abundance of fall chinook salmon in the Snake River basin has become a growing concern. Effective recovery efforts for fall chinook salmon cannot be developed until we increase our knowledge of the factors that are limiting the various life history stages. This study attempts to identify those physical and biological factors which influence spawning of fall chinook salmon in the free-flowing Snake River and their rearingmore » and seaward migration through Columbia River basin reservoirs.« less
ERIC Educational Resources Information Center
Smarte, Lynn
This 1999 annual report, summarizing the accomplishments of the Educational Resources Information System (ERIC) system in 1998, begins with a section that highlights progress towards meeting goals, as well as selected statistics. The second section, comprising the bulk of the report, provides an overview of ERIC, including the ERIC database, user…
ERIC Educational Resources Information Center
Smarte, Lynn
This 2000 annual report, summarizing the accomplishments of the Educational Resources Information Center (ERIC) system in 1999, begins with a section that highlights progress towards meeting goals, as well as selected statistics. The second section, comprising the bulk of the report, provides an overview of ERIC, including the ERIC database, user…
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-07
... [email protected] . SUPPLEMENTARY INFORMATION: OMB No.: OMB 0412-New. Form No.: N/A. Title: Mentor-Prot[eacute]g[eacute] Program Annual Report. Type of Review: New. Purpose: The mentors are required to report on the progress made under each of active Mentor-Prot[eacute]g[eacute] Agreement annually throughout...
Continuous Improvement: Building for the Future. Superintendent's 20th Annual Report, 2009
ERIC Educational Resources Information Center
State of Hawaii Department of Education, 2009
2009-01-01
This paper presents the Superintendent's 20th Annual Report, a comprehensive overview of Hawaii's public schools for school year 2008-09. This report contains essential progress indicators and measures, as well as highlights and comparisons of core educational data presented in a concise and user-friendly format. Appended are: (1) Glossary; (2)…
Missouri Coordinating Board for Higher Education Fiscal Year 2005 Annual Report
ERIC Educational Resources Information Center
Fitch, Gregory G.; Stein, Robert; Matchefts, Jim; Peterson, Dan; Imhoff, Donna; Miner, Brenda; Fennewald, Amy
2005-01-01
The Coordinating Board for Higher Education and the Missouri Department of Higher Education present this fiscal year 2005 Annual Report to inform individuals of the state's status and progress in higher education. The Coordinating Board for Higher Education (CBHE) began the 2005 calendar year with a number of significant changes. The board and its…
The Annual Review of Information Science and Technology: Its Aims and Impact.
ERIC Educational Resources Information Center
Cuadra, Carlos A.
The major aims of the "Annual Review of Information Science and Technology" are (1) to describe and appraise progress in information science and technology; (2) to provide a systematic, dependable tool that can relieve professionals from winnowing through a wealth of literature in their field each year; (3) to direct the reader to…
The State of the Cities, 1999. Third Annual Report.
ERIC Educational Resources Information Center
Department of Housing and Urban Development, Washington, DC. Office of Policy Development and Research.
This third annual report discusses recent progress and challenges that lie ahead for U.S. cities and metropolitan regions. Part 1 examines social and economic trends affecting U.S. cities and the potential for a city/suburb alliance to promote a common agenda that would address the challenges and seize the opportunities reflected in the trends.…
Lutein/zeaxanthin for the treatment of age-related cataract: AREDS2 randomized trial report no. 4.
Chew, Emily Y; SanGiovanni, John Paul; Ferris, Frederick L; Wong, Wai T; Agron, Elvira; Clemons, Traci E; Sperduto, Robert; Danis, Ronald; Chandra, Suresh R; Blodi, Barbara A; Domalpally, Amitha; Elman, Michael J; Antoszyk, Andrew N; Ruby, Alan J; Orth, David; Bressler, Susan B; Fish, Gary E; Hubbard, George B; Klein, Michael L; Friberg, Thomas R; Rosenfeld, Philip J; Toth, Cynthia A; Bernstein, Paul
2013-07-01
Age-related cataract is a leading cause of visual impairment in the United States. The prevalence of age-related cataract is increasing, with an estimated 30.1 million Americans likely to be affected by 2020. To determine whether daily oral supplementation with lutein/zeaxanthin affects the risk for cataract surgery. The Age-Related Eye Disease Study 2 (AREDS2), a multicenter, double-masked clinical trial, enrolled 4203 participants, aged 50 to 85 years, at risk for progression to advanced age-related macular degeneration. Participants were randomly assigned to daily placebo; lutein/zeaxanthin, 10mg/2mg; omega-3 long-chain polyunsaturated fatty acids, 1 g; or a combination to evaluate the effects on the primary outcome of progression to advanced age-related macular degeneration. Cataract surgery was documented at annual study examination with the presence of pseudophakia or aphakia, or reported during telephone calls at 6-month intervals between study visits. Annual best-corrected visual acuity testing was performed. A secondary outcome of AREDS2 was to evaluate the effects of lutein/zeaxanthin on the subsequent need for cataract surgery. A total of 3159 AREDS2 participants were phakic in at least 1 eye and 1389 of 6027 study eyes underwent cataract surgery during the study, with median follow-up of 4.7 years. The 5-year probability of progression to cataract surgery in the no lutein/zeaxanthin group was 24%. For lutein/zeaxanthin vs no lutein/zeaxanthin, the hazard ratios for progression to cataract surgery was 0.96 (95% CI, 0.84-1.10; P = .54). For participants in the lowest quintile of dietary intake of lutein/zeaxanthin, the hazard ratio comparing lutein/zeaxanthin vs no lutein/zeaxanthin for progression to cataract surgery was 0.68 (95% CI, 0.48-0.96; P = .03). The hazard ratio for 3 or more lines of vision loss was 1.03 (95% CI, 0.93-1.13; P = .61 for lutein/zeaxanthin vs no lutein/zeaxanthin). Daily supplementation with lutein/zeaxanthin had no statistically significant overall effect on rates of cataract surgery or vision loss. clinicaltrials.gov Identifier: NCT00345176.
ERIC Educational Resources Information Center
Glaser, Robert
A study of response latency in a drill-and-practice task showed that variability in latency measures could be reduced by the use of self-pacing procedures, but not by the detailed analysis of latency into separate components. Experiments carried out on instructional history variables in teaching a mirror image, oblique line discrimination, showed…
Annual Research Progress Report for Fiscal Year 1983,
1983-10-01
Crossover Study. (0) C-60-83 tifedipine in Patients with Recurrent Episodes of Bronchospasm. 124 (0) C-66-83 Epidemiological , Clinical and Therapeutic...study in the utilization of a phased response disaster plan. Third World Congress in Emergency and Disaster Medicine, 25 May 83, Rome, Italy...nonallergic rhinitis with eosinophilia (HARES)? and b. Are patients with MARES - or any identifiable subset thereof - at particular risk of developing lower
Department of Clinical Investigation Annual Research Progress Report, Fiscal Year 1993. Volume 1
1993-10-01
monocytes, total periphernuclear cells, and alveolar macrophages from four study groups : patients with concurrent Mycobacterium tuberculosis (MTBI and...research design, similar to the Solomon Four Group design will be utilized to determine if the educational intervention provided has an impact on nurses...members with approved protocols: 173 Number of approved protocols held by this group : 230 Drug evaluation/comparison studies : 94 (Does not include
Annual Research Progress Report (William Beaumont Army Medical Center) FY 1983
1994-03-23
Algeo, Dept of Radiology) .............................................. 58 Pacheco, EJ: 93/53 (0) Phase II Study of Interferon-Modulated Indium- Il 1 ...76 Lutz, P: 92/68 ( 1 ) Nursing Effects on Mastectomy Patients’ Perception of Self Esteem ............................ 77 Nufer, E: 93/08 (C) Cardiac...15 1 Kravitz, MB: 93/49 (0) A Comparison Study of Midazolam and Pentobarbital Versus Pentobarbital A),=e in the Effective Sedation of
Air pollution effects on food quality. 2nd annual progress report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pell, E.J.
1979-02-01
Progress is reported in studies to determine the effect of acute, toxic exposures of ozone to alfalfa, potato, and soybean plants. The objective has been to correlate the foliar response with alterations in quality of the edible portion of the plant viz. the leaf, tuber and seed of alfalfa, potato and soybean, respectively. In 1977 we (1) modified our fumigation facilities, (2) developed protocol for studies with alfalfa and potato, and (3) conducted studies on flavonoid status of alfalfa and a series of parameters of potato tubers. In 1978 we (1) conducted more indepth studies with alfalfa, (2) repeated themore » potato study, (3) began to develop protocol for measuring additional parameters of alfalfa and potato quality, and (4) developed protocol for cultivating and exposing soybean plants.« less
2012-10-01
critically ill patients using artificial neural network synthesised by genetic algorithm,” The Lancet, vol. 347, (no. 9009), pp. 1146-1150, 1996...criterion (Table 2). Statistical Analysis Annual progress report page 46 Data synthesis was conducted according to the study design separately as... synthesis of results across included studies was not performed in the study by Detterbeck and Gibson4 which was undertaken in our study. Another unique
Maitra, S K; Dey, M
1994-08-01
The pinealocytes in male roseringed parakeets (Psittacula krameri) were studied following bilateral castration and/or therapeutic administration of testosterone during the preparatory (June-July), progressive (Nov.-Dec.), pre-breeding (Jan.-Feb.) and breeding (March-April) phases of the annual testicular cycle. The responses of the pineal to either treatment were found to be almost identical throughout the investigation. In each reproductive phase, the pineal appeared to be hypertrophied following castration and the effect was reversed by therapeutic administration of testosterone, while hormonal treatment to the intact parakeets induced regressive changes in the pinealocytes. Collectively, the results of the current study support the hypothesis that the testis through its hormone testosterone exerts inhibitory influences on the activity of pineal, and may thus be considered as being involved in the determination of an inverse relationship between the pineal and the testis during the annual cycle of free-living parakeets.
International VLBI Service for Geodesy and Astrometry: 1999 Annual Report
NASA Technical Reports Server (NTRS)
Vandenberg, Nancy R. (Editor)
1999-01-01
This volume of reports is the 1999 Annual Report of the International VLBI Service for Geodesy and Astrometry -IVS. The individual reports were contributed by VLBI groups in the international geodetic community who constitute the components of IVS. The 1999 Annual Report documents the work of the IVS components for the year ending March 1, 1999, the official inauguration date of IVS. As the newest of the space technique services, IVS decided to publish this Annual Report as a reference to our organization and its components. The entire contents of this Annual Report also appear on the IVS website at: http://ivscc.gsfc.nasa.gov/pub/arl999. The IVS 1999 Annual Report will be a valuable reference for information about IVS and its components. This Annual Report will serve as a baseline from which we can measure the anticipated progress of IVS in coming years.
International VLBI Service for Geodesy and Astronomy
NASA Technical Reports Server (NTRS)
Vandenberg, Nancy R. (Editor); Baver, Karen D. (Editor)
2004-01-01
This volume of reports is the 2003 Annual Report of the International VLBI Service for Geodesy and Astrometry (IVS). The individual reports were contributed by VLBI groups in the international geodetic and astrometric community who constitute the permanent components of IVS. The IVS 2003 Annual Report documents the work of the IVS components for the calendar year 2003, our fifih year of existence. The reports describe changes, activities, and progress of the IVS. Many thanks to all IVS components who contributed to this Annual Report. The entire contents of this Annual Report also appear on the IVS web site at http://ivscc.gsfc.nasa.gov/publications/ar2OO3
International VLBI Service for Geodesy and Astrometry 2013 Annual Report
NASA Technical Reports Server (NTRS)
Baver, Karen D.; Behrend, Dirk; Armstrong, Kyla L.
2014-01-01
This volume of reports is the 2013 Annual Report of the International VLBI Service for Geodesy and Astrometry (IVS). The individual reports were contributed by VLBI groups in the international geodetic and astrometric community who constitute the permanent components of IVS. The IVS 2013 Annual Report documents the work of the IVS components for the calendar year 2013, our fifteenth year of existence. The reports describe changes, activities, and progress of the IVS. Many thanks to all IVS components who contributed to this Annual Report. With the exception of the first section and the last section, the contents of this Annual Report also appear on the IVS Web site at http://ivscc.gsfc.nasa.gov/publications/ar2013.
International VLBI Service for Geodesy and Astrometry 2012 Annual Report
NASA Technical Reports Server (NTRS)
Baver, Karen D.; Behrend, Dirk; Armstrong, Kyla L.
2013-01-01
This volume of reports is the 2012 Annual Report of the International VLBI Service for Geodesy and Astrometry (IVS). The individual reports were contributed by VLBI groups in the international geodetic and astrometric community who constitute the permanent components of IVS. The IVS 2012 Annual Report documents the work of the IVS components for the calendar year 2012, our fourteenth year of existence. The reports describe changes, activities, and progress ofthe IVS. Many thanks to all IVS components who contributed to this Annual Report. With the exception of the first section and parts of the last section (described below), the contents of this Annual Report also appear on the IVS Web site athttp:ivscc.gsfc.nasa.gov/publications/ar2012
FY2017 Technology Integration Annual Progress Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
The 2017 Technology Integration Annual Progress Report covers 27 multi-year projects funded by the Vehicle Technologies Office. The report includes information on 20 competitively awarded projects, ranging from training on alternative fuels and vehicles for first responders, to safety training and design for maintenance facilities housing gaseous fuel vehicles, to electric vehicle community partner programs. It also includes seven projects conducted by several of VTO’s national laboratory partners, Argonne National Laboratory, Oak Ridge National Laboratory and the National Renewable Energy Laboratory. These projects range from a Technical Assistance project for business, industry, government and individuals, to the EcoCar 3 Studentmore » Competition, and the Fuel Economy Information Project.« less
1993-01-01
effect of cisapride on the symptoms of unexplained upper abdominal pain, nausea, vomiting, anorexia, early satiety, bloating/ distension in patients with...for 30 minutes following eccentric exercise will less the 3 indices of delayed-onset muscle soreness (DOMS): perceived muscular soreness, reduced...post-exercise and the Talag Pain Rating Scale will be used to assess muscular soreness. Progress: No progress report was furnished by the principal
Research on Speech Perception. Progress Report No. 8, January 1982-December 1982.
ERIC Educational Resources Information Center
Pisoni, David B.; And Others
Summarizing research activities from January 1982 to December 1982, this is the eighth annual report of research on speech perception, analysis and synthesis conducted in the Speech Research Laboratory of the Department of Psychology at Indiana University. The report includes extended manuscripts, short reports, progress reports, and information…
Presentation at the 41st Annual Winter Meeting of The Toxicology Forum - From Assay to Assessment: Incorporating High Throughput Strategies into Health and Safety Evaluations on Building Scientific Confidence in Read-Across: Progress in using HT Data to inform Read-Across Perfor...
Research on Speech Perception. Progress Report No. 9, January 1983-December 1983.
ERIC Educational Resources Information Center
Pisoni, David B.; And Others
Summarizing research activities from January 1983 to December 1983, this is the ninth annual report of research on speech perception, analysis and synthesis conducted in the Speech Research Laboratory of the Department of Psychology at Indiana University. The report includes extended manuscripts, short reports, and progress reports. The report…
Straight A's: Public Education Policy and Progress. Volume 6, Number 16
ERIC Educational Resources Information Center
Amos, Jason, Ed.
2006-01-01
"Straight A's: Public Education Policy and Progress" is a biweekly newsletter that focuses on education news and events both in Washington, DC and around the country. The following articles are included in this issue: (1) Paying Double: United States Spends Over $1.4 Billion Annually on Remedial Education for Recent High School…
Research on Spoken Language Processing. Progress Report No. 21 (1996-1997).
ERIC Educational Resources Information Center
Pisoni, David B.
This 21st annual progress report summarizes research activities on speech perception and spoken language processing carried out in the Speech Research Laboratory, Department of Psychology, Indiana University in Bloomington. As with previous reports, the goal is to summarize accomplishments during 1996 and 1997 and make them readily available. Some…
[Regulation of terpene metabolism]. Annual progress report, March 15, 1988--March 14, 1989
DOE Office of Scientific and Technical Information (OSTI.GOV)
Croteau, R.
1989-12-31
Progress in understanding of the metabolism of monoterpenes by peppermint and spearmint is recorded including the actions of two key enzymes, geranyl pyrophosphate:limonene cyclase and a UDP-glucose dependent glucosyl transferase; concerning the ultrastructure of oil gland senescence; enzyme subcellular localization; regulation of metabolism; and tissue culture systems.
Workplace Charging Challenge Progress Update 2016: A New Sustainable Commute
DOE Office of Scientific and Technical Information (OSTI.GOV)
None, None
In the 2016 Workplace Charging Challenge annual survey, partners shared for the how their efforts were making an impact in their communities and helped identify best practices for workplace charging. The Workplace Charging Challenge Progress Update highlights the findings from this survey and recognizes leading employers for their workplace charging efforts.
A Goal for North Carolina's Schools. First in America 2001 Progress Report.
ERIC Educational Resources Information Center
Cunningham, Elizabeth Kolb, Ed.; Thompson, Charles L., Ed.
This second annual report details North Carolina's performance and progress since 2000 in the five goal areas: high student performance; every child ready to learn; safe, orderly, and caring schools; quality teachers and administrators; and strong family, business, and community support. Over the years, North Carolina's education system has…
DOE Office of Scientific and Technical Information (OSTI.GOV)
In June 2016, the Workplace Charging Challenge distributed its third annual survey to 295 partners with the goal of tracking partners' progress and identifying trends in workplace charging. This document summarizes findings from the survey and highlights accomplishments of the EV Everywhere Workplace Charging Challenge.
Outcomes for Children Served through IDEA's Early Childhood Programs: 2014-15
ERIC Educational Resources Information Center
Early Childhood Technical Assistance Center, 2016
2016-01-01
In 2014-2015, children with delays or disabilities who received services under the Individuals with Disabilities Act (IDEA) showed greater than expected developmental progress. Many children exited the program functioning within age expectations, and most made progress. States' Part C and Part B Preschool programs report data annually on three…
Koye, Digsu N; Magliano, Dianna J; Reid, Christopher M; Jepson, Christopher; Feldman, Harold I; Herman, William H; Shaw, Jonathan E
2018-05-18
Reduced glomerular filtration rate (GFR) in the absence of albuminuria is a common manifestation of chronic kidney disease (CKD) in diabetes. However, the frequency with which it progresses to end-stage kidney disease (ESKD) is unknown. Multicenter prospective cohort study. We included 1,908 participants with diabetes and reduced GFR enrolled in the Chronic Renal Insufficiency Cohort (CRIC) Study in the United States. Urinary albumin and protein excretion. Incident ESKD, CKD progression (ESKD or ≥50% reduction in estimated GFR [eGFR] from baseline), and annual rate of decline in kidney function. ESKD was ascertained by self-report and by linkage to the US Renal Data System. We used Cox proportional hazards modeling to estimate the association of albuminuria and proteinuria with incident ESKD or CKD progression and linear mixed-effects models to assess differences in eGFR slopes among those with and without albuminuria. Mean eGFR at baseline was 41.2mL/min/1.73m 2 . Normal or mildly increased 24-hour urinary albumin excretion (<30mg/d) at baseline was present in 28% of participants, but in only 5% of those progressing to ESKD. For those with baseline normal or mildly increased albuminuria, moderately increased albuminuria (albumin excretion, 30-299mg/d), and 2 levels of severely increased albuminuria (albumin excretion, 300-999 and ≥1,000mg/d): crude rates of ESKD were 7.4, 34.8, 78.7, and 178.7 per 1,000 person-years, respectively; CKD progression rates were 17.0, 61.4, 130.5, and 295.1 per 1,000 person-years, respectively; and annual rates of eGFR decline were -0.17, -1.35, -2.74, and -4.69mL/min/1.73m 2 , respectively. We were unable to compare the results with healthy controls. In people with diabetes with reduced eGFRs, the absence of albuminuria or proteinuria is common and carries a much lower risk for ESKD, CKD progression, or rapid decline in eGFR compared with those with albuminuria or proteinuria. The rate of eGFR decline in normoalbuminuric CKD was similar to that reported for the general diabetic population. Copyright © 2018 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.
Annual Progress Report (SEATO Medical Research Laboratory)
1975-03-01
Vibrio porahemolyticus Infection in Thailand . 105 Cholera Study at Samutsongkram . . . . .. 110 Detection of Specific Bacterial Antigen by...clinical picture of the mild form of the disease needs to be described. Dehydration was not as severe as that seen in infection with Vibrio cholera ...co-trimoxazole, neomycin, erythromycin and streptomycin. Only 6 , and 62 % of the vibrios tested were sensitive to ampicillin and colistin
Analysis of Restricted Natural Gas Supply Cases
2004-01-01
The four cases examined in this study have progressively greater impacts on overall natural gas consumption, prices, and supply. Compared to the Annual Energy Outlook 2004 reference case, the no Alaska pipeline case has the least impact; the low liquefied natural gas case has more impact; the low unconventional gas recovery case has even more impact; and the combined case has the most impact.
Annual Research Progress Report, FY 1991
1991-09-30
59 86/114 0 Natural History of HTLV-III Infection and Disease in a United States Military Community (PR) ............... . ............ 60 86/120 0...Malignant Lymphomas ..................... 142 90/147 0 SWOG 8819 Central Lymphoma Repository Tissue Procurement Protocol ........................... 143 90...Adjuvant Chemo- therapy with or without Endocrine Therapy in High- Risk, Node Negative Breast Cancer Patients and a Natural History Followup Study in Low
Clinical Investigation Program Annual Progress Report
1989-09-30
initiatives for the study of relatedness of bacterial and HLA antigens as they influence autoimmune diseases. Microbiology Service - FY 89 An in-house...1030 87/103 0 Identification of Those at Risk for Osteoporotic Hip Fractures, by an Noninvasive Measurement (P) (PR)... 105 87/104 0 SWOG 8600 - A...233 82/302 0 The Evaluation of Recently Introduced, Commercially Available Clinical Microbiology Products for Possible
ERIC Educational Resources Information Center
Wilkerson, Kevin; Perusse, Rachelle; Hughes, Ashley
2013-01-01
This study compares school-wide Annual Yearly Progress (AYP) results in Indiana schools earning the Recognized ASCA Model Program (RAMP) designation (n = 75) with a sample of control schools stratified by level and locale (n = 226). K-12 schools earning the RAMP designation in 2007, 2008, and 2009 comprise the experimental group. Findings indicate…
Charting the Course: Four Years of the Thomas W. Payzant School on the Move Prize
ERIC Educational Resources Information Center
d'Entremont, Chad; Norton, Jill; Bennett, Michael; Piazza, Peter
2012-01-01
Since 2006, the Thomas W. Payzant School on the Move (SOM) Prize has been awarded annually to a Boston public school that has made significant progress in improving student achievement. This case study identifies the structures and strategies that best serve students in prizewinning schools, provides a profile of each of the four winning schools…
ERIC Educational Resources Information Center
Illuminating Engineering Research Inst., New York, NY.
Several of the more familiar Illuminating Engineering Research Institute projects which have been chronicled progressively during the past several years are discussed in this report. Those elaborated on are--(1) visual performance and illumination, (2) roadway visual tasks, (3) color preference studies, (4) glare from large sources, (5) discomfort…
Psychomotor and Perceptual Speed Abilities and Skilled Performance.
1999-02-01
of the perceptual speed and touch-panel psychomotor tests used in the current project were administered to School of Dentistry students. Although...progress). Touch-panel monitor based psychomotor tests for predicting skilled performance: An exploratory study with School of Dentistry students...Paper to be submitted for presentation at the 1999 Human Factors and Ergonomics Society annual meeting. Ackerman, P. L., & Kanfer, R. (1993
ERIC Educational Resources Information Center
Dow, Mirah J.; McMahon-Lakin, Jacqueline
2012-01-01
To address the presence or absence of school librarians in Kansas public schools, a study using analysis of covariance (ANCOVA) was designed to investigate staffing levels for library media specialists (LMSs), the label used for school librarians in licensed-personnel data in Kansas, and student achievement at the school level. Five subject areas…
ERIC Educational Resources Information Center
Southern Rural Development Center, State College, MS.
Summarizing Southern Rural Development Center (SRDC) activities during the October 1977-September 1978 fiscal year, this fifth annual report indicates that with Title V funding SRDC has continued its efforts to bring research and extension personnel together to work on problems in rural development. Support for programs and research at land grant…
DOE Office of Scientific and Technical Information (OSTI.GOV)
G. B. Mitchem
2001-08-22
This annual progress and performance evaluation report discusses the groundwater remedial actions in the 100 Area, including the interim actions at the 100-HR-3 and 100-KR-4 Operable Units, and also discusses the expedited response action in the 100-NR-2 operable unit.
Annual Report of the Center for Research in Human Learning, 1967-68.
ERIC Educational Resources Information Center
Minnesota Univ., Minneapolis. Center for Research in Human Learning.
This document constitutes the narrative portion of the Annual Progress Report of the Center for Research in Human Learning for the period 15 June 1967 to 15 June 1968. It was submitted to the National Science Foundation, the National Institute of Child Health and Human Development, and the Graduate School of the University of Minnesota as an…
ERIC Educational Resources Information Center
Office of Special Education and Rehabilitative Services, US Department of Education, 2014
2014-01-01
The 34th Annual Report to Congress on the Implementation of the "Individuals with Disabilities Education Act," 2012 describes our nation's progress in: (1) providing a free appropriate public education (FAPE) for all children with disabilities; (2) ensuring that the rights of children with disabilities and their parents are protected;…
ERIC Educational Resources Information Center
Office of Special Education and Rehabilitative Services, US Department of Education, 2014
2014-01-01
The 35th Annual Report to Congress on the Implementation of the "Individuals with Disabilities Education Act," 2013 describes the nation's progress in (1) providing a free appropriate public education (FAPE) for all children with disabilities, (2) ensuring that the rights of children with disabilities and their parents are protected, (3)…
Ultra-Dense Quantum Communication Using Integrated Photonic Architecture: First Annual Report
2011-08-24
REPORT Ultra-Dense Quantum Communication Using Integrated Photonic Architecture: First Annual Report 14. ABSTRACT 16. SECURITY CLASSIFICATION OF: The...goal of this program is to establish a fundamental information-theoretic understand of quantum secure communication and to devise a practical...scalable implementation of quantum key distribution protocols in an integrated photonic architecture. We report our progress on experimental and
Graduation and Dropout Statistics Annual Report. Report to the Legislature [2016-17
ERIC Educational Resources Information Center
Weaver-Randall, Katie; Ireland, Lisa
2018-01-01
Under the guidelines of state law, RCW 28A.175.010, the Office of Superintendent of Public Instruction (OSPI) is required to report annually on the educational progress of public school students in grades 7-12. At the direction of the U.S. Department of Education, Washington uses the adjusted cohort graduation calculation to track a single cohort…
Gan, Wen Qi; Allen, Ryan W; Brauer, Michael; Davies, Hugh W; Mancini, G B John; Lear, Scott A
2014-01-01
Objectives Epidemiological studies have demonstrated associations between long-term exposure to traffic-related air pollution and coronary heart disease (CHD). Atherosclerosis is the principal pathological process responsible for CHD events, but effects of traffic-related air pollution on progression of atherosclerosis are not clear. This study aimed to investigate associations between long-term exposure to traffic-related air pollution and progression of carotid artery atherosclerosis. Setting Healthy volunteers in metropolitan Vancouver, Canada. Participants and outcome measures 509 participants aged 30–65 years were recruited and followed for approximately 5 years. At baseline and end of follow-up, participants underwent carotid artery ultrasound examinations to assess atherosclerosis severity, including carotid intima-media thickness, plaque area, plaque number and total area. Annual change of each atherosclerosis marker during the follow-up period was calculated as the difference between these two measurements divided by years of follow-up. Living close to major roads was defined as ≤150 m from a highway or ≤50 m from a major road. Residential exposures to traffic-related air pollutants including black carbon, fine particles, nitrogen dioxide and nitric oxide were estimated using high-resolution land-use regression models. The data were analysed using general linear models adjusting for various covariates. Results At baseline, there were no significant differences in any atherosclerosis markers between participants living close to and those living away from major roads. After follow-up, the differences in annual changes of these markers between these two groups were small and not statistically significant. Also, no significant associations were observed with concentrations of traffic-related air pollutants including black carbon, fine particles, nitrogen dioxide and nitric oxide. Conclusions This study did not find significant associations between traffic-related air pollution and progression of carotid artery atherosclerosis in a region with lower levels and smaller contrasts of ambient air pollution. PMID:24710134
Jaber, Rana; Mzayek, Fawaz; Madhivanan, Purnima; Khader, Yousuf; Maziak, Wasim
2016-04-01
Little evidence regarding longitudinal predictors of cigarette smoking progression is available from developing countries. This study aimed to identify gender-specific individual and social predictors of cigarette smoking progression among a school-based sample of adolescents in Irbid, Jordan. A total of 1781 seventh graders (participation rate 95%) were enrolled and completed an annual self-administered questionnaire from 2008 through 2011. Students who reported "ever-smoking a cigarette" at baseline or in the subsequent follow-up but not being "heavy daily smokers" (>10 cigarettes per day) were eligible for this analysis (N = 669). Grouped-time survival analyses were used to identify predictors of cigarette smoking progression in boys and girls. Among the study sample, 38.3% of students increased the frequency and /or amount of cigarette smoking during the 3 years of follow-up. Among individual factors, the urge to smoke in the morning predicted smoking progression for boys and girls. The independent predictors of cigarette smoking progression were friends' smoking and attending public schools in boys, and siblings' smoking in girls. Discussing the dangers of smoking with family members was protective for girls. Boys and girls progressed similarly in cigarette smoking once they initiated the habit. Progression among girls was solely family-related, while it was peer-related for boys. © The Author 2015. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
NASA Astrophysics Data System (ADS)
1987-07-01
The U.S. Navy is conducting a long-term program to monitor for possible effects from the operation of its Extremely Low Frequency (ELF) Communications System to resident biota and their ecological relationships. This report documents progress of the following studies: soil amoeba; soil and litter arthropoda and earthworm studies; biological studies on pollinating insects: megachilid bees; and small vertebrates: small mammals and nesting birds.
Robbins, W.D.
1972-01-01
Hydrologic investigations of urban areas in Texas were begun by the U.S. Geological Survey in 1954. These studies are now in progress in Austin, Houston, Dallas, Dallas County, Fort Worth, San Antonio, and Bryan. Hydrologic investigations of urban areas in Texas were begun by the U.S. Geological Survey in 1954. These studies are now in progress in Austin, Houston, Dallas, Dallas County, Fort Worth, San Antonio, and Bryan. 1. To determine, on the basis of historical data and hydrologic analyses, the magnitude and frequency of floods. 2. To document and define the areal extent of floods of greater than ordinary magnitude. 3. To determine the effect of urban development on flood peaks and volume. 4. To provide applied research facilities for studies at Texas A & M University at College Stations. This report, the first in a series of reports to be published annually, is primarily applicable to objectives 2, 3, and 4. The report presents the basic hydrologic data collected in two study areas during the 1969 water year (October 1, 1968, to September 30, 1969) and basic hydrologic data collected during part of the 1968 water year (April 5, 1968, to September 30, 1968). The locations of the two basins within the study area, Burton Creek and Hudson Creek, are shown on figure 1.
Building America Systems Integration Research Annual Report: FY 2012
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gestwick, M.
2013-05-01
This document is the Building America FY2012 Annual Report, which includes an overview of the Building America Program activities and the work completed by the National Renewable Energy Laboratory and the Building America industry consortia (the Building America teams). The annual report summarizes major technical accomplishments and progress towards U.S. Department of Energy Building Technologies Program's multi-year goal of developing the systems innovations that enable risk-free, cost effective, reliable and durable efficiency solutions that reduce energy use by 30%-50% in both new and existing homes.
Walter Reed Army Institute of Research Annual Progress Report Fiscal Year 1983
1983-10-01
period between the injury and the observation of clinical seizures is essential to developing rational preventive measures which might be initiated...of novel pharmacologic interventions to prevent development of seizures following brain injury . Further studies are under way todetermine if the...Cyanide Poisoning: Studies with a Canine Model (New) 94 3M161102BS10 RESEARCH ON MILITARY DISEASE, INJURY AND’HEALTH HAZARDS 95 201 Viral Infections
Research in radiobiology. Annual report of work in progress in the internal irradiation program
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1979-03-31
The toxicity, retention, biological effects, distribution, decorporation and measuring techniques of radionuclides are discussed. Calculations of trabecular bone formation rates from tetracycline labeling is included. The characteristics of trabecular bone in the Rhesus monkey are discussed. Studies on the early retention and distribution of radium 224 in beagles are included. Studies on the decorporation of plutonium and americium in dogs by DTPA and salicylic acid are presented.
Zhang, Xinbo; Dastiridou, Anna; Francis, Brian A; Tan, Ou; Varma, Rohit; Greenfield, David S; Schuman, Joel S; Sehi, Mitra; Chopra, Vikas; Huang, David
2016-12-01
To identify baseline structural parameters that predict the progression of visual field (VF) loss in patients with open-angle glaucoma. Multicenter cohort study. Participants from the Advanced Imaging for Glaucoma (AIG) study were enrolled and followed up. VF progression is defined as either a confirmed progression event on Humphrey Progression Analysis or a significant (P < .05) negative slope for VF index (VFI). Fourier-domain optical coherence tomography (FDOCT) was used to measure optic disc, peripapillary retinal nerve fiber layer (NFL), and macular ganglion cell complex (GCC) thickness parameters. A total of 277 eyes of 188 participants were followed up for 3.7 ± 2.1 years. VF progression was observed in 83 eyes (30%). Several baseline NFL and GCC parameters, but not disc parameters, were found to be significant predictors of progression on univariate Cox regression analysis. The most accurate single predictors were the GCC focal loss volume (FLV), followed closely by NFL-FLV. An abnormal GCC-FLV at baseline increased risk of progression by a hazard ratio of 3.1. Multivariate Cox analysis showed that combining age and central corneal thickness with GCC-FLV in a composite index called "Glaucoma Composite Progression Index" (GCPI) further improved the accuracy of progression prediction. GCC-FLV and GCPI were both found to be significantly correlated with the annual rate of change in VFI. Focal GCC and NFL loss as measured by FDOCT are the strongest predictors for VF progression among the measurements considered. Older age and thinner central corneal thickness can enhance the predictive power using the composite risk model. Copyright © 2016 Elsevier Inc. All rights reserved.
Bird atlasing in the United States
Robbins, C.S.
1977-01-01
Since the Breeding Bird Survey provides an annual quantitative sample of about 75% of the 1? blocks of latitude and longitude in every state except Alaska and Hawaii, and 47% of the 1/2? blocks (equivalent on the average to a 48 km square), no national Atlas based on merely presence or absence has been contemplated. Conventional atlases are in progress in the states of Maryland (2.5 km), Massaohusetts (5 km) and Vermont (5 km) and in parts of 3 other states. Quantitative studies including mapping have been published for North Dakota (10 km) and are in progress in Wyoming (1?). A Montana project (1?) is continuing.
Capoulade, Romain; Clavel, Marie-Annick; Dumesnil, Jean G; Chan, Kwan L; Teo, Koon K; Tam, James W; Côté, Nancy; Mathieu, Patrick; Després, Jean-Pierre; Pibarot, Philippe
2013-02-01
The objective of this substudy of the ASTRONOMER (Aortic Stenosis Progression Observation: Measuring Effects of Rosuvastatin) trial was to examine the association between insulin resistance and progression of left ventricular hypertrophy (LVH) in patients with aortic stenosis (AS). In a recent cross-sectional study, the authors reported that the metabolic syndrome was associated with an increased prevalence of concentric LVH in patients with AS. As a central feature of the metabolic syndrome, insulin resistance could be an important mediator of this association. This substudy included 250 of 269 patients enrolled in ASTRONOMER. Follow-up was 3.4 ± 1.3 years. Insulin resistance was evaluated using the homeostatic assessment model (HOMA) index, and patients were dichotomized using the median HOMA index value (1.24). The rate of LVH progression was estimated by calculating the annualized change in LV mass index (LVMi), measured on echocardiography. The presence of LVH was defined as an LVMi >47 g/m(2.7) in women and >49 g/m(2.7) in men. There was a significant progression of LVH among the patients without LVH at baseline (n = 134; p < 0.0001) but not in those with it (n = 116; p = NS). In those without LVH at baseline, the annualized progression rate of LVMi was significantly faster in the subset with HOMA >1.24 compared to that in the subset with HOMA <1.24 (2.49 ± 4.38 g/m(2.7)/year vs. -0.03 ± 3.90 g/m(2.7)/year; p = 0.001). During follow-up, LVH developed in 46% of patients with HOMA >1.24 compared to 11% of those with HOMA <1.24 (p = 0.0005). Independent predictors of faster LVH progression identified on multivariate analysis were history of hypertension (p = 0.048), degree of aortic valve calcification (p = 0.035), and HOMA index (p = 0.02). In this ASTRONOMER substudy, insulin resistance was a powerful independent predictor of progression to LVH in patients with AS. Visceral obesity and ensuing insulin resistance may thus present novel therapeutic targets in AS patients. Copyright © 2013 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.
The natural history of spinocerebellar ataxia type 1, 2, 3, and 6
Jacobi, H.; Bauer, P.; Giunti, P.; Labrum, R.; Sweeney, M.G.; Charles, P.; Dürr, A.; Marelli, C.; Globas, C.; Linnemann, C.; Schöls, L.; Rakowicz, M.; Rola, R.; Zdzienicka, E.; Schmitz-Hübsch, T.; Fancellu, R.; Mariotti, C.; Tomasello, C.; Baliko, L.; Melegh, B.; Filla, A.; Rinaldi, C.; van de Warrenburg, B.P.; Verstappen, C.C.P.; Szymanski, S.; Berciano, J.; Infante, J.; Timmann, D.; Boesch, S.; Hering, S.; Depondt, C.; Pandolfo, M.; Kang, J.-S.; Ratzka, S.; Schulz, J.; Tezenas du Montcel, S.
2011-01-01
Objective: To obtain quantitative data on the progression of the most common spinocerebellar ataxias (SCAs) and identify factors that influence their progression, we initiated the EUROSCA natural history study, a multicentric longitudinal cohort study of 526 patients with SCA1, SCA2, SCA3, or SCA6. We report the results of the 1- and 2-year follow-up visits. Methods: As the primary outcome measure we used the Scale for the Assessment and Rating of Ataxia (SARA, 0–40), and as a secondary measure the Inventory of Non-Ataxia Symptoms (INAS, 0–16) count. Results: The annual increase of the SARA score was greatest in SCA1 (2.18 ± 0.17, mean ± SE) followed by SCA3 (1.61 ± 0.12) and SCA2 (1.40 ± 0.11). SARA progression in SCA6 was slowest and nonlinear (first year: 0.35 ± 0.34, second year: 1.44 ± 0.34). Analysis of the INAS count yielded similar results. Larger expanded repeats and earlier age at onset were associated with faster SARA progression in SCA1 and SCA2. In SCA1, repeat length of the expanded allele had a similar effect on INAS progression. In SCA3, SARA progression was influenced by the disease duration at inclusion, and INAS progression was faster in females. Conclusions: Our study gives a comprehensive quantitative account of disease progression in SCA1, SCA2, SCA3, and SCA6 and identifies factors that specifically affect disease progression. PMID:21832228
English Language Learners and Their Academic Progress: 2010-2011
ERIC Educational Resources Information Center
Shneyderman, Aleksandr
2012-01-01
This is the 2010-11 annual report on the academic progress of English language learners in the Miami-Dade County Public Schools. The purpose of the report is to: (1) Describe the demographic characteristics of students classified as English Language Learners (ELL) in the Miami-Dade County Public Schools (M-DCPS); (2) Provide data regarding ELL…
ERIC Educational Resources Information Center
Piland, Joseph; And Others
During the annual convention of the Illinois Vocational Association, a survey was conducted to determine perceptions about progress being made toward implementation of the Education for Employment (EFE) policy. Questions focused on four perceptions held by the EFE community about the needed changes: knowledge and awareness of expected changes;…
Year 3 Magnet Schools Assistance Program Annual Progress Report, 2009-10. E&R Report No. 10.09
ERIC Educational Resources Information Center
Brasfield, Jon; Cárdenas, Virginia
2010-01-01
The three Magnet Schools Assistance Program (MSAP) schools: East Garner International Baccalaureate Magnet Middle School (EGMMS), Garner International Baccalaureate Magnet High School (GMHS), and Southeast Raleigh Leadership and Technology Magnet High School (SRMHS) have shown progress on MSAP performance measures during the 3rd year of the grant.…
Annual Technical Progress Report for Emergency School Assistance Program, Title 45, 1970-71.
ERIC Educational Resources Information Center
Lindsey, Randall B.
This paper presents a technical progress report of two programs conducted with funds provided under the Emergency School Assistance Program. One, the Mobile Learning Unit, said to have been designed to measure changes in fourth and fifth grade students' self-concept in a reorganized desegregated school environment, focuses on whether a positive…
ERIC Educational Resources Information Center
Yates, Shirley M.
2004-01-01
Career and further education aspirations, educational progress and perceptions of the learning environment were measured annually over three years in primary and secondary boys from a single sex non-government school, following the changeover to coeducation. Hierarchical Linear Modelling analyses revealed the significant role played by the career…
California Energy Systems for the 21st Century 2016 Annual Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Van Randwyk, J.; Boutelle, A.; McClelland, C.
The California Energy Systems for the 21st Century (CES-21) Program is a public-private collaborative research and development program between the California Joint Utilities1 and Lawrence Livermore National Laboratory (LLNL). The purpose of this annual report is to provide the California Public Utilities Commission (CPUC or Commission) with a summary of the 2016 progress of the CES-21 Program.
ERIC Educational Resources Information Center
Oregon State Dept. of Education, Salem.
The Oregon Report Card is an annual portrait of the state's public schools. The first five sections describe statewide progress toward implementing Oregon's Educational Act for the 21st Century, some of the state's exemplary school-improvement programs, and the clear relationship between Oregon's program and national education goals. The remaining…
ERIC Educational Resources Information Center
Australian National Training Authority, Brisbane.
This document contains the first two volumes of a three-volume annual national report on Australia's vocational education and training (VET) system. Volume 1, which constitutes approximately 30% of the document, details progress in achieving the following national priorities: (1) a quality national training system that provides value for money…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tombari, C.
2005-09-01
The U.S. Department of Energy's Million Solar Roofs Initiative (MSR) is a unique public-private partnership aimed at overcoming market barriers for photovoltaics (PV), solar water heating, transpired solar collectors, solar space heating and cooling, and pool heating. This report contains annual progress reports from 866 partners across the United States.
ERIC Educational Resources Information Center
Office of Special Education and Rehabilitative Services (ED), Washington, DC. Div. of Innovation and Development.
The report documents the nation's progress in providing a free appropriate public education for all children with handicaps under the provisions of the Education for All Handicapped Children Act, Public Law 94-142. Chapter I presents national statistics reported annually by the states (e.g., a 1.6% increase in number of handicapped children served…
LVC Architecture Roadmap Implementation - Results of the First Two Years
2012-03-01
NOTES Presented at the Simulation Interoperability Standards Organization?s (SISO) Spring Simulation Interoperability Workshop ( SIW ), 26-30 March...presented at the semi-annual Simulation Interoperability Workshops ( SIWs ) and the annual Interservice/Industry Training, Simulation & Education Conference...I/ITSEC), as well as other venues. For example, a full-day workshop on the initial progress of the effort was conducted at the 2010 Spring SIW [2
Li, Gang; Cao, Zhe; Wu, Xiao-Wei; Wu, Hui-Kun; Ma, Yi; Wu, Bin; Wang, Wei-Qing; Cheng, Jian; Zhou, Zi-Hua; Tu, Yuan-Chao
2017-12-15
Arterial stiffness is an independent indicator of cardiovascular risk. Autoantibodies (AAs) against angiotensin AT 1 receptor (AT 1 -AAs) and α 1 -adrenergic receptor (α 1 -AAs) are important in the pathogenesis of hypertension. We identified the types of AT 1 -AAs and α 1 -AAs in normotensive subjects, with the aim of determining whether these antibodies predict aortic stiffness progression. Carotid-femoral pulse wave velocity (cf-PWV) was used to measure aortic stiffness. Overall, 816 subjects (71% of those invited) underwent a medical examination and evaluation of aortic stiffness. The types of AT 1 -AAs and α 1 -AAs were measured at baseline. Meanwhile, plasma renin, angiotensin II (Ang II), and norepinephrine (NE) concentrations were measured at baseline and follow-up. Baseline mean cf-PWV was 9.90 ± 0.84 m/s and follow-up was 10.51 ± 1.12 m/s. The annualized ΔPWV was 0.12 ± 0.08 m/s/year. At the end of follow-up, 129 normotensive subjects developed hypertension and 144 subjects had PWV progression. After adjustment for covariates, AA type was independently associated with ΔPWV, annualized ΔPWV, and abnormal PWV. In our study, the risk of developing hypertension (RR =2.028, 95% CI: 1.227-3.351, P =0.006) and PWV progression (RR =2.910, 95% CI: 1.612-5.253, P <0.001) in AA-positive subjects was significantly higher than that in AA-negative subjects. Receiver operating characteristic (ROC) curve showed AA had an identify power to discriminate subjects with or without PWV and hypertension progression. We have shown for the first time that the types of A 1 -AAs and α 1 -AAs are independent predictors for aortic stiffness progression in normotensive subjects. Our data collectively support the utility of these AAs as potential markers of aortic stiffness. © 2017 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society.
Alam, Nazmul; Hajizadeh, Mohammad; Dumont, Alexandre; Fournier, Pierre
2015-01-01
To assess social inequalities in the use of antenatal care (ANC), facility based delivery (FBD), and modern contraception (MC) in two contrasting groups of countries in sub-Saharan Africa divided based on their progress towards maternal mortality reduction. Six countries were included in this study. Three countries (Ethiopia, Madagascar, and Uganda) had <350 MMR in 2010 with >4.5% average annual reduction rate while another three (Cameroon, Zambia, and Zimbabwe) had >550 MMR in 2010 with only <1.5% average annual reduction rate. All of these countries had at least three rounds of Demographic and Health Surveys (DHS) before 2012. We measured rate ratios and differences, as well as relative and absolute concentration indices in order to examine within-country geographical and wealth-based inequalities in the utilization of ANC, FBD, and MC. In the countries which have made sufficient progress (i.e. Ethiopia, Madagascar, and Uganda), ANC use increased by 8.7, 9.3 and 5.7 percent, respectively, while the utilization of FBD increased by 4.7, 0.7 and 20.2 percent, respectively, over the last decade. By contrast, utilization of these services either plateaued or decreased in countries which did not make progress towards reducing maternal mortality, with the exception of Cameroon. Utilization of MC increased in all six countries but remained very low, with a high of 40.5% in Zimbabwe and low of 16.1% in Cameroon as of 2011. In general, relative measures of inequalities were found to have declined overtime in countries making progress towards reducing maternal mortality. In countries with insufficient progress towards maternal mortality reduction, these indicators remained stagnant or increased. Absolute measures for geographical and wealth-based inequalities remained high invariably in all six countries. The increasing trend in the utilization of maternal care services was found to concur with a steady decline in maternal mortality. Relative inequality declined overtime in countries which made progress towards reducing maternal mortality. PMID:25853423
Chen, Yanxian; Chang, Billy Heung Wing; Ding, Xiaohu; He, Mingguang
2016-11-22
In the present study we attempt to use hypothesis-independent analysis in investigating the patterns in refraction growth in Chinese children, and to explore the possible risk factors affecting the different components of progression, as defined by Principal Component Analysis (PCA). A total of 637 first-born twins in Guangzhou Twin Eye Study with 6-year annual visits (baseline age 7-15 years) were available in the analysis. Cluster 1 to 3 were classified after a partitioning clustering, representing stable, slow and fast progressing groups of refraction respectively. Baseline age and refraction, paternal refraction, maternal refraction and proportion of two myopic parents showed significant differences across the three groups. Three major components of progression were extracted using PCA: "Average refraction", "Acceleration" and the combination of "Myopia stabilization" and "Late onset of refraction progress". In regression models, younger children with more severe myopia were associated with larger "Acceleration". The risk factors of "Acceleration" included change of height and weight, near work, and parental myopia, while female gender, change of height and weight were associated with "Stabilization", and increased outdoor time was related to "Late onset of refraction progress". We therefore concluded that genetic and environmental risk factors have different impacts on patterns of refraction progression.
United States Army Biomedical Research and Development Laboratory Annual Progress Report FY90
1991-01-01
pesticide . Parallel and follow-on studies will include hydrolysis products of nerve agents , vesicants, and agents of...Division FO Fog oil FORSCOM U.S. Army Forces Command FY Fiscal year 249 GA The nerve agent tabun GB The nerve agent soman GD The nerve agent sarin GLP... Nerve Agents , Industrial Hygiene Sampling, Microbiology, Combustion Products, Liquid Gun Propellant, Organic Chemistry, Inorganic
Annual Research Progress Report. Fiscal Year 1989. Volume 2
1989-10-01
Date : 4 --- ---- Date of Periodic Review - -- Results Objective(s): i) Develop a conscious, tethered or lightly sedated , nonhuman primate model...Approach: All animal studies will be conducted at Incarnate Word College Division of Nursing and the Sciences. All procedures will be done as outlined...Gary Zarr, LTC, AN Academy of Health Sciences Dept/Svc Associate Investigators: Dpartment of Nursing Jeff Serogrham, LTC, AN Key Words: Accumulative
Annual Research Progress Report (U.S. Army Institute of Dental Research, Washington, DC)
1978-10-01
postoperative edema, minimal postoperative scarring, sterilization of infected wounds, minimal pain and a sharply demarcated operative field. This...evaluate pain killing medicaments used in military dental practice. The hazards involved in the use of various drugs will be studied and...Surgical treatment of orofacial wounds frequently requires use of high-speed equipment and ultrasonic sealers. Water from dental units has been
Clinical Investigation Program Annual Progress Report
1993-09-30
272 93/200A 0 Comparison of Healing Rates of Bones Plated Following Fracture, Among Yucatan Swine Having Open and Closed Physes...Study Objective: Compare two enteral formulas in respect to nutritional aspects. (16) Technical Approach: Protocol will take place in SICU. (17...Protocol #: 93/200A (3) Status: Ongoing (4) Title: Comparison of Healing Rates of Bones Plated Following Fractures, Among Yucatan Swine Having Open and
ERIC Educational Resources Information Center
Carroll, Patricia E.; Bailey, Alison L.
2016-01-01
English language proficiency assessments (ELPA) are used in the United States to measure annually the English language progress and proficiency of English-language learners (ELLs), a subgroup of language minority students who receive language acquisition support mandated and largely funded by Title III (NCLB, 2001). ELPA proficient and…
Application of MAGSAT to lithospheric modeling in South America
NASA Technical Reports Server (NTRS)
Keller, G. R.; Lidiak, E. G. (Principal Investigator)
1982-01-01
Progress continues on all aspects of the project. The prime emphasis is on the Rayleigh wave study and determination of both group and phase velocity dispersion is almost complete. Existing data sets were prepared for inversion. A paper on the relation of MAGSAT anomalies to the main tectonic provinces of South America was delivered at the annual meeting of the Society of Exploration Geophysicists.
FY2014 Energy Storage R&D Annual Progress Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
none,
The Energy Storage research and development (R&D) subprogram within the DOE Vehicle Technologies Office (VTO) provides support and guidance for projects focusing on batteries for plug-in electric vehicles. Program targets focus on overcoming technical barriers to enable market success including: (1) significantly reducing battery cost, (2) increasing battery performance (power, energy, durability), (3) reducing battery weight & volume, and (4) increasing battery tolerance to abusive conditions such as short circuit, overcharge, and crush. This report describes the progress made on the research and development projects funded by the Energy Storage subprogram in 2014. You can download individual sections at themore » following website, http://energy.gov/eere/vehicles/downloads/vehicle-technologies-office-2014-energy-storage-rd-annual-report.« less
Marine biomass program: plant breeding and genetics. Annual report, September 1984-December 1985
DOE Office of Scientific and Technical Information (OSTI.GOV)
Neushul, M.; Harger, B.W.W.; Lewis, R.J.
1986-03-01
By building on past efforts and adding to the data base that has been assembled, and through collaborative research with others, progress has been made toward the long-term goal of growing macroalgae in the sea as a future source of substitute natural gas. It is encouraging that the authors program is being emulated in Japan and Sweden, and that there is growing interest in using the unique GRI kelp seedstock collection by workers in Germany, Japan, Alaska, Oregon, California, and elsewhere. This annual report discusses progress made in propagating kelps, and the floating gulf-weed, Sargassum. Work on kelp genetics hasmore » revealed high levels of compatability between species and genera, based on 166 hybridization tests.« less
Amariglio, Rebecca E; Donohue, Michael C; Marshall, Gad A; Rentz, Dorene M; Salmon, David P; Ferris, Steven H; Karantzoulis, Stella; Aisen, Paul S; Sperling, Reisa A
2015-04-01
Several large-scale Alzheimer disease (AD) secondary prevention trials have begun to target individuals at the preclinical stage. The success of these trials depends on validated outcome measures that are sensitive to early clinical progression in individuals who are initially asymptomatic. To investigate the utility of the Cognitive Function Instrument (CFI) to track early changes in cognitive function in older individuals without clinical impairment at baseline. Longitudinal study from February 2002 through February 2007 at participating Alzheimer's Disease Cooperative Study sites. Individuals were followed up annually for 48 months after the baseline visit. The study included 468 healthy older individuals (Clinical Dementia Rating scale [CDR] global scores of 0, above cutoff on the modified Mini-Mental State Examination and Free and Cued Selective Reminding Test) (mean [SD] age, 79.4 [3.6] years; age range, 75.0-93.8 years). All study participants and their study partners completed the self and partner CFIs annually. Individuals also underwent concurrent annual neuropsychological assessment and APOE genotyping. The CFI scores between clinical progressors (CDR score, ≥0.5) and nonprogressors (CDR score, 0) and between APOE ε4 carriers and noncarriers were compared. Correlations of change between the CFI scores and neuropsychological performance were assessed longitudinally. At 48 months, group differences between clinical progressors and non-progressors were significant for self (2.13, SE=0.45, P<.001), partner (5.08, SE=0.59, P<.001), and self plus partner (7.04, SE=0.83, P<.001) CFI total scores. At month 48, APOE ε4 carriers had greater progression than noncarriers on the partner (1.10, SE=0.44, P<.012) and self plus partner (1.56, SE=0.63, P<.014) CFI scores. Both self and partner CFI change were associated with longitudinal cognitive decline (self, ρ=0.32, 95% CI, 0.13 to 0.46; partner, ρ=0.56, 95% CI, 0.42 to 0.68), although findings suggest self-report may be more accurate early in the process, whereas accuracy of partner report improves when there is progression to cognitive impairment. Demonstrating long-term clinical benefit will be critical for the success of recently launched secondary prevention trials. The CFI appears to be a brief, but informative potential outcome measure that provides insight into functional abilities at the earliest stages of disease.
de Vlas, Sake J.; Fischer, Peter U.; Weil, Gary J.; Goldman, Ann S.
2013-01-01
The Global Program to Eliminate Lymphatic Filariasis (LF) has a target date of 2020. This program is progressing well in many countries. However, progress has been slow in some countries, and others have not yet started their mass drug administration (MDA) programs. Acceleration is needed. We studied how increasing MDA frequency from once to twice per year would affect program duration and costs by using computer simulation modeling and cost projections. We used the LYMFASIM simulation model to estimate how many annual or semiannual MDA rounds would be required to eliminate LF for Indian and West African scenarios with varied pre-control endemicity and coverage levels. Results were used to estimate total program costs assuming a target population of 100,000 eligibles, a 3% discount rate, and not counting the costs of donated drugs. A sensitivity analysis was done to investigate the robustness of these results with varied assumptions for key parameters. Model predictions suggested that semiannual MDA will require the same number of MDA rounds to achieve LF elimination as annual MDA in most scenarios. Thus semiannual MDA programs should achieve this goal in half of the time required for annual programs. Due to efficiency gains, total program costs for semiannual MDA programs are projected to be lower than those for annual MDA programs in most scenarios. A sensitivity analysis showed that this conclusion is robust. Semiannual MDA is likely to shorten the time and lower the cost required for LF elimination in countries where it can be implemented. This strategy may improve prospects for global elimination of LF by the target year 2020. PMID:23301115
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kasten, P.R.; Rittenhouse, P.L.; Bartine, D.E.
1983-06-01
During 1982 the High-Temperature Gas-Cooled Reactor (HTGR) Technology Program at Oak Ridge National Laboratory (ORNL) continued to develop experimental data required for the design and licensing of cogeneration HTGRs. The program involves fuels and materials development (including metals, graphite, ceramic, and concrete materials), HTGR chemistry studies, structural component development and testing, reactor physics and shielding studies, performance testing of the reactor core support structure, and HTGR application and evaluation studies.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Napier, Bruce A.; Krupka, Kenneth M.; Fellows, Robert J.
2004-12-02
This Annual Progress Report describes the work performed and summarizes some of the key observations to date on the U.S. Nuclear Regulatory Commission’s project Assessment of Food Chain Pathway Parameters in Biosphere Models, which was established to assess and evaluate a number of key parameters used in the food-chain models used in performance assessments of radioactive waste disposal facilities. Section 2 of this report describes activities undertaken to collect samples of soils from three regions of the United States, the Southeast, Northwest, and Southwest, and perform analyses to characterize their physical and chemical properties. Section 3 summarizes information gathered regardingmore » agricultural practices and common and unusual crops grown in each of these three areas. Section 4 describes progress in studying radionuclide uptake in several representative crops from the three soil types in controlled laboratory conditions. Section 5 describes a range of international coordination activities undertaken by Project staff in order to support the underlying data needs of the Project. Section 6 provides a very brief summary of the status of the GENII Version 2 computer program, which is a “client” of the types of data being generated by the Project, and for which the Project will be providing training to the US NRC staff in the coming Fiscal Year. Several appendices provide additional supporting information.« less
Economic growth and health progress in England and Wales: 160 years of a changing relation.
Tapia Granados, José A
2012-03-01
Using data for England and Wales during the years 1840-2000, a negative relation is found between economic growth--measured by the rate of growth of gross domestic product (GDP)--and health progress--as indexed by the annual increase in life expectancy at birth (LEB). That is, the lower is the rate of growth of the economy, the greater is the annual increase in LEB for both males and females. This effect is much stronger, however, in 1900-1950 than in 1950-2000, and is very weak in the 19th century. It appears basically at lag zero, though some short-lag effects of the same negative sign are found. In the other direction of causality, there are very small effects of the change in LEB on economic growth. These results add to an emerging consensus that in the context of long-term declining trends, mortality oscillates procyclically during the business cycle, declining faster in recessions. Therefore, LEB increases faster during recessions than during expansions. The investigation also shows how the relation between economic growth and health progress changed in England and Wales during the study period. No evidence of cointegration between income--as indexed by GDP or GDP per capita--and health--as indexed by LEB--is found. Copyright © 2012 Elsevier Ltd. All rights reserved.
Nuclear Technology Division annual progress report for period ending June 30, 1972
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
1972-10-01
This document is a report of progress on technical programs of the Nuclear Technology,Division of Aerojet Nuclear Company for FY 72 ending June 30, 1972. It contains abstracts or expansions of abstracts of papers which have been published within the year. In these cases, preprints or reprints of the articles available. Results of work in progress are also reported; since this work is of a preliminary nature, the authors should be contacted before including any reference to these works in other publications.
Annual Report of the Secretary of Defense on Reserve Forces for Fiscal Year 1975
1976-06-08
acquisition and distribution of equipment continued to be achieved. Progress was made in both filling uxisting shortfalls and in modernization and... progress of the KOTC flight instruction programs. vArmy Air Force Units Participating 200 56 161 Students Enrolled 412 436 2,036 Students Completed 321 361...Resurve Forces IV Current Status and Progress Made in 4 Strengthening the Reserve Components * A. General 4 1. 24 Division rorce 4 4ii 2. Total Force
Colombo, Leonardo; Montesano, Giovanni; Sala, Barbara; Patelli, Fabio; Maltese, Paolo; Abeshi, Andi; Bertelli, Matteo; Rossetti, Luca
2018-06-26
The aim of this study is to analyze and compare the progression of photoreceptor atrophy among siblings affected by retinitis pigmentosa by means of spectral SD-OCT. Fifty three eyes of 27 patients belonging to 12 family clusters were analyzed. To assess the annual progression rate of photoreceptor atrophy, the ellipsoid zone (EZ) line was measured in OCT sections through the fovea. We used multivariate generalized mixed effects to model the rate of progression and its relation to the initial ellipsoid zone line width. During our 4.84 years (± 1.44) mean follow up time (range 3-7) 53 eyes were examined. The ellipsoid zone line width declined with a yearly average rate of 76.4 μm (4.16% / year) (p-value < 0.0001). Progression rates were poorly correlated within family clusters (p-value = 0.23) and showed statistical difference between affected siblings (p-value = 0.007). There was no correlation between inter-familiar progression rate and mode of inheritance (p-value = 0.98) as well as between age and ellipsoid zone line width among siblings (p-value = 0.91). RP could be extremely heterogeneous even among siblings: an accurate and sensitive method to follow the progression of the disease is fundamental for future development of clinical trials and therapy strategies.
Park, Kay-Hyun; Chung, Suryeun; Kim, Dong Jung; Kim, Jun Sung; Lim, Cheong
2017-05-01
For a moderately dilated ascending aorta (diameter 35-54 mm), current guidelines recommend continuous annual or semi-annual examinations with computed tomography or magnetic resonance imaging. However, few data have shown the yield and benefit of such a protocol. This study aimed to investigate the fate of a moderately dilated ascending aorta and thereby determine the adequate imaging interval. In our institutional database, we identified adult patients having an ascending aortic diameter ≥40 mm in contrast-enhanced computed tomography and follow-up imaging(s) after ≥1 year. Of the 509 patients (mean age 67.2 ± 10.4 years) enrolled in the study, the maximal diameter of the ascending aorta was compared between the first and last images. Also, their medical records were reviewed to investigate the associated illness and clinical events. The mean growth rate of the patients with a 40-44 mm ( n = 321), 45-49 mm ( n = 142) and ≥50 mm ( n = 46) ascending aorta was 0.3 ± 0.5, 0.3 ± 0.5 and 0.7 ± 0.9 mm/year, respectively. During the mean interval of 4.3 ± 2.4 years, significant progression (diameter increase by ≥5 mm) occurred in 3.4, 5.6 and 21.7%, respectively. The 3- to 5-year rates of freedom from significant progression were 99.1%-96.5% (40-44 mm) and 97.8%-96.4% (45-49 mm). In multivariate analysis, initial ascending aortic diameter ≥45 mm and aortic valve regurgitation were significantly associated with significant progression. Acute type A aortic dissection occurred in 5 patients (1%), before the maximal diameter of the ascending aorta reached 55 mm or significant progression was observed. For a moderately dilated ascending aorta not exceeding 45 mm in maximal diameter and stable in the first annual follow-up image, a 3- to 4-year interval would be reasonable before subsequent imaging. More frequent imaging may be warranted in patients with aortic valve insufficiency or with an aortic diameter ≥45 mm. © The Author 2017. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.
Basic research on radiant burners. Semi-annual report, through July 1991
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sullivan, J.D.
1991-10-01
Basic performance characteristics of radiant burners are explored in the broad-based study combining theoretical modeling and experimental validation of predictions. The work included fabrication of catalyzed substrates and fibers; incorporation of the catalysts into burners; testing of catalysts; and investigation of new catalyst sources. The progress of the study is detailed and further plans are outlined. A report on the preparation of palladium catalysts by Andre Blaise Kooh is included in the appendix.
Clinical Investigation Program Annual Progress Report.
1985-09-30
027 78/114 In Vitro Effect of Minoxidil on Collagen Produc- tion by Normal and Scleroderma Fibroblasts (C) (PR...effect of minoxidil on collagen production Dy normal and scleroderma fibroblasts. Previously titled: The use of minoxidil in treating progressive...Svc: (tO) Assoc Investigators: (11) Key Words: scleroderma, minoxidil Thomas P. O’Barr PhD, DAC fibroblasts, collagen Ellen Swanson MS, DAC Don
State of the World, 1985: A Worldwatch Institute Report on Progress toward a Sustainable Society.
ERIC Educational Resources Information Center
Brown, Lester R.; And Others
The second of a series of annual reports designed to provide a global assessment of progress toward a sustainable society, this publication monitors changes in the global resource base (land, water, energy, and biological support systems), focusing particularly on how these changes affect the economy. Included in the report are news on innovative…
Burn Treatment: Annual Research Progress Report.
1975-06-30
in addition to direct or indirect measurements of blood pressure. Central venous pressures are measured relatively frequently and, on occasion, a... Central venous pressure assessment. 5. EKG. 46 I 6. Sponge weighing. 7. Measurement of urine output during surgery. B. RESPIRATION 1. Counting of...start a central venous line prior to adminis- tration of vasopressors. The patient became progressively more hypo- tensive and bradycardiac, which
Straight A's: Public Education Policy and Progress. Volume 12, Number 8
ERIC Educational Resources Information Center
Amos, Jason, Ed.
2012-01-01
"Straight A's: Public Education Policy and Progress" is a biweekly newsletter that focuses on education news and events both in Washington, DC and around the country. The following articles are included in this issue: (1) Tax Returns: On Tax Day 2012, a 90 Percent High School Graduation Rate Would Yield $1.8 Billion Annually in Additional Tax…
ERIC Educational Resources Information Center
Poon, Derek
Covering the period January 1 through June 30, 1975, this second semi-annual report on the Applied Fishery Science Program operative at Sheldon Jackson College in Sitka, Alaska presents information regarding program progress and Alaska Native students involved in science education. Specifically, this report details: Planning and Coordination…
FY2016 Lightweight Materials Annual Progress Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
None, None
The Lightweight Materials research and development (R&D) area within the DOE Vehicle Technologies Office (VTO) provides support and guidance for many cutting-edge automotive technologies under development. Research focuses on addressing critical barriers to commercializing lightweight materials for passenger and commercial vehicles. This report describes the progress made on the research and development projects funded by the Lightweight Materials area.
International VLBI Service for Geodesy and Astrometry
NASA Technical Reports Server (NTRS)
Vandenberg, Nancy R. (Editor); Baver, Karen D. (Editor)
2001-01-01
This volume of reports is the 2000 Annual Report of the International Very Long Base Interferometry (VLBI) Service for Geodesy and Astrometry (IVS). The individual reports were contributed by VLBI groups in the international geodetic and astrometric community who constitute the components of IVS. The 2000 Annual Report documents the work of these IVS components over the period March 1, 1999, through December 31, 2000. The reports document changes, activities, and progress of the IVS. The entire contents of this Annual Report also appear on the IVS web site at http://ivscc.gsfc.nasa.gov/publications/ar2000.
ERIC Educational Resources Information Center
New Jersey Department of Education, 2009
2009-01-01
The Commissioner's annual report provides the Legislature with information reported by school districts concerning incidents of serious student misconduct grouped into the following four major reporting categories: violence, vandalism, weapons, and substance abuse. An analysis of trends yields indications of progress and of ongoing concern, and…
ERIC Educational Resources Information Center
New Jersey Department of Education, 2010
2010-01-01
The Commissioner's annual report provides the Legislature with information reported by school districts concerning incidents of serious student misconduct grouped into the following four major reporting categories: violence, vandalism, weapons, and substance abuse. An analysis of trends yields indications of progress and of ongoing concern, and…
International Laser Ranging Services (ILRS) 2001 Annual Report
NASA Technical Reports Server (NTRS)
Pearlman, Michael (Editor); Torrence, Mark (Editor); Noll, Carey (Editor)
2002-01-01
This 2001 Annual Report of the International Laser Ranging Services (ILRS) is comprised of individual contributions from ILRS components within the international geodetic community. This report documents the work of the ILRS components for the year 2001. The report documents changes and progress of the ILRS. This document is also available on the ILRS Web site at http://ilrs.gsfc.nasa.gov/reports/ilrs_reports/ilrsar_2001.html.
ERIC Educational Resources Information Center
Roberts, Brian
2005-01-01
Purpose: Aims to report on the 60th ASCD Annual Conference and Exhibit Show 2005, held in Orlando Florida, 2-4 April 2005 by the Association for Supervision and Curriculum Development. Design/methodology/approach: Discusses the presentations such as the obesity epidemic in children, educational progress in schools, creating capacity for learning,…
ERIC Educational Resources Information Center
Balfanz, Robert; Bridgeland, John M.; Fox, Joanna Hornig; DePaoli, Jennifer L.; Ingram, Erin S.; Maushard, Mary
2014-01-01
This fifth annual update on America's high school dropout crisis shows that, for the first time in history, the nation has crossed the 80 percent high school graduation rate threshold and remains on pace, for the second year in a row, to meet the goal of a 90 percent high school graduation rate by the Class of 2020. This report highlights key…
Developing Precision Immunotherapies - Annual Plan
Despite remarkable progress, cancer immunotherapies can be toxic to some patients. Learn how NCI-funded research will extend the benefits of immunotherapy to more patients through biomarker research and collaboration.
Gorno-Tempini, Maria Luisa; Murray, Ryan C; Rankin, Katherine P; Weiner, Michael W; Miller, Bruce L
2004-12-01
Recent clinical and pathological studies have suggested that frontotemporal lobar degeneration (FTLD) and corticobasal syndrome (CBS) show clinical and pathological overlap. We present four years of longitudinal clinical, cognitive and anatomical data in the case of a 56-year-old woman, AS, whose clinical picture evolved from FTLD to CBS. For the first three years, AS showed a progressive speech and language disorder compatible with a diagnosis of the nonfluent aphasia variant of FTLD. At year four, 10 years after her first symptom, AS developed the classical clinical signs of CBS, including alien limb phenomenon and dystonia. Voxel-based morphometry (VBM) applied to AS's four annual scans showed progression of atrophy from the inferior posterior frontal gyrus, to the left insula and finally to the medial frontal lobe. This case demonstrates the clinical overlap between FTLD and CBS and shows that the two can appear in the same patient at different stages of the disease in relation to the progression of anatomical damage.
NASA Technical Reports Server (NTRS)
Toksoz, M. Nafi
1988-01-01
The long-term objective of this project is to interpret NASA's Crustal Dynamics measurements (SLR) in the Eastern Mediterranean region in terms of relative plate movements and intraplate deformation. The approach is to combine realistic modeling studies with analysis of available geophysical and geological observations to provide a framework for interpreting NASA's measurements. This semi-annual report concentrates on recent results regarding the tectonics of Anatolia and surrounding regions from ground based observations. Also reported on briefly is progress in the use of the Global Positioning System to densify SLR observations in the Eastern Mediterranean. Reference is made to the previous annual report for a discussion of modeling results.
ERIC Educational Resources Information Center
Radunzel, Justine; Noble, Julie
2012-01-01
This study compared the effectiveness of ACT[R] Composite score and high school grade point average (HSGPA) for predicting long-term college success. Outcomes included annual progress towards a degree (based on cumulative credit-bearing hours earned), degree completion, and cumulative grade point average (GPA) at 150% of normal time to degree…
Annual Progress Report - Fiscal Year 1978.
1978-10-01
outbreak of Rift Valley fever (RVF) which occurred for the first time in history throughout Egypt. Because there were thousands of cases, with hemorrhagic...lobar pneumonias, and the study of viruses, such as JE, which appear capable of entering the central nervous system from the nasal mu- cosa via...professional staff, each with a high degree of competence in virology, received the vaccine. Each volunteer underwent a com- plete history and physical
Department of Clinical Investigation Annual Progress Report: Fiscal Year 1989
1989-01-01
Between Plasma Oxygen Permeability 10 and Atherosclerotic Coronary Artery Disease as Determined by Cardiac Catheterization C89-03 A Double-Blind, Parallel...Local Anesthetic Administration During Cardiac Catheterization C89-05 Intravenous Sotalol for the Termination of P3 Paroxysmal Supraventricular... History and Treatment of Patients with Non- Invasive Intraductal Adenocarcinoma H85-09 (**8H-85-I) Phase III Study of Subtotal Lymphoid Irradiation or
Application of Wear Debris Analysis to Aircraft Hydraulic Systems.
1982-05-10
C. Wescott, "Predicting and Determining Failures by Means of Ferrography ", paper given at Ninth Annual FAA International Aviation Maintenance...morphological characteristics (reference (c)). In this particular effort the morphologi- cal studies were performed by means of analytical ferrography ...peak of 191,000 at 225 hours. As time progressed, the index again began to fall and returned to Ref: (c) "Wear Particle Atlas " Naval Air Engineering
Surgical Tooth Implants, Combat and Field.
1984-07-15
and identify by block number) --- This Annual Report summarizes progress to date on a long-term implant study of a serrated ceramic dental implant...upper two parts of the implant, post and core and crown, are conventional metaT materials. A series of graded dental implants have been produced to...throughout the experimental period. Periodic radio- graphic analyses of dental implants verify this observation. Gross and microscopic patho- logic analyses
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
1963-12-01
Separate abstracts were prepared for twenty-eight of the thirty-three papers. The other papers deal with whole-rock Rb- Sr ages of Ontario norite and micropegmatite and the Southern Rhodesia Great Dyke, Sr isotopes in vein type mineral deposits, whole-rock Rb-- Sr studies of volcanics, and accuracy in Sr / sup 87//Sr/sup 86/ measurements. (D.C.W.)
Annual Research Progress Report, Fiscal Year 1981,
1981-10-01
Joseph P. Murgo, M.D., COL, MC Key Words: Patent ductus arteriosus Cyanotic congenital heart disease Accumulative MEDCASE Est Accumulative Periodic Cost... Ductus Arteriosus in Neonates 47 with Cyanotic Congenital Heart Disease. (T) C-37-79 Ankle Trauma Study. (0) 48 C-5-80 Lopressor Intervention Trial. (0...Maintenance of Patency of the Ductus Arteriosus in Neonates with Cyanotic Congenital Heart Disease Start Date: Aug 79 Est Comp Date: Principal
Annual Research Progress Report, 1 July 1971
1971-07-01
weanlings sexed , there were 9 males and 14 females . Until recent work done by the Department of Medical 171 Ecology of this Unit, this rat was considered a...and in a pattern quite different from infections in E. histolytica-free patients. Miscellaneous Studies: Findings during the past year include: (1...after the nation-wide floods and subsequent intensive public health measures. (12) The dynamics of Chromobacterium violaceum infection of gibbons at
Hydrodynamic Agents in the Littoral Environment. Phase 1 Progress Report
2007-07-06
GEOINT) in the coastal zone. HALE is aimed at improving baseline information that supports decision-making in the dynamic littoral region, and...intertidal zone. It is already apparent from this study that the most useful DEMs should be built annually or seasonally in dynamic regions such as the Han...higher harmonics of the principal lunar and solar semidiurnal constituents. Figure 3-1 illustrates the processes ( dynamics ) and sedimentary
Annual Conference on HAN-Based Liquid Propellants. Volume 1
1989-05-01
Fischer . This situation is obviously not ideal and effort is being made to find a suitable method . However we have been assured that there has been...CLASSIFICATION OF HAN-BASED LIQUID PROPELLANT LP101. S. Westlake --..---- ------------ 64 POSSIBLE TEST METHODS TO STUDY THE THERMAL STABILITY OF...specifications for LP. The phase of the program which is now in progress has dealt with (1) reviewing. recommending and developing applicable analytical methods
Annual Research Progress Report, Fiscal Year 1980,
1980-10-01
Uric Acid Levels at 36 Weeks Gestation as 45 Screening Test for Preeclampsia as an Aid to Further Manage- ment. (0) DEPARTMENT OF PSYCHIATRY...Investigators: CPT Ellis M. Knight, MC Key Words: Serum Uric Acid Preeclampsia Accumulative MEDCASE Est Accumulative Periodic Ap-roved for continuation...Cost: 0 OMA Cost: 0 Review Results Study Objective: To demonstrate that: A. Serum uric acid level is a simple specific screening test for preeclampsia
Annual Progress Report, January 1, 1969 through December 31, 1969.
1970-02-01
or extended. E. The Role of CAI in Curriculum Revision I The Intermediate Science Curriculum Study (ISCS)* (Dr. Ernest Burkman, i Director and Dr David...Educational Research, FSU. Henry T. Lippert , Ed.D., 1967, Education, University of Illinois, Research Associate in the CAI Center and Assistant...Walter Dick, and Henry T Lippert , Tech Report 3, Florida State University, Tallahassee, 1968 "A Systematic Investigation of Three Facets of Programmed
Understanding Statistics - Cancer Statistics
Annual reports of U.S. cancer statistics including new cases, deaths, trends, survival, prevalence, lifetime risk, and progress toward Healthy People targets, plus statistical summaries for a number of common cancer types.
Sung, Heungsup; Kang, Sang-Moo; Lee, Moo-Song; Kim, Tai Gyu; Cho, Young-Keol
2005-01-01
We have previously showed that long-term intake of Korean red ginseng (KRG) delayed disease progression in human immunodeficiency virus type 1 (HIV-1)-infected patients. In the present study, to investigate whether this slow progression was affected by KRG intake alone or in combination with HLA factor, we analyzed clinical data in 68 HIV-1-infected patients who lived for more than 5 years without antiretroviral therapy. The average KRG intake over 111.9 ± 31.3 months was 4,082 ± 3,928 g, and annual decrease in CD4 T cells was 35.0 ± 28.7/μl. Data analysis showed that there are significant inverse correlations between the HLA prognostic score (0.29 ± 1.19) and annual decrease in CD4 T cells (r = −0.347; P < 0.01) as well as between the amount of KRG intake and annual decrease in CD4 T cells (r = −0.379; P < 0.01). In addition, KRG intake significantly slowed the decrease in CD4 T cells even when influence of HLA class I was statistically eliminated (repeated-measure analysis of variance; P < 0.05). We also observed significant correlation between KRG intake and a decrease in serum-soluble CD8 antigen level (r = 0.62; P < 0.001). In conclusion, these data show that KRG intake independently and significantly affected the slow depletion of CD4 T cells irrespective of HLA class I. PMID:15817756
DOE Office of Scientific and Technical Information (OSTI.GOV)
Burgess, Dave
2003-11-01
This annual report is a precursor to the final technical report we will be writing the next contract period. Consequently, this report, covering the period between September 27, 2002, and September 26, 2003, represents a progress report towards the final technical report we anticipate completing by September 26, 2004. Sample analysis and field work have progressed well and we anticipate no further delays. There are 4 objectives: (1) To quantify secondary production Moses Lake; (2) To quantify the influence of predation on target fishes in Moses Lake; (3) To quantify mortality of selected fished in Moses Lake; and (4) Tomore » assess effects of habitat changes from shoreline development and carp on the fish community in Moses Lake.« less
LLE 2010 Annual Report October 2009 - September 2010
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
2011-01-01
The fiscal year ending September 2010 (FY10) concluded the third year of the third five-year renewal of Cooperative Agreement DE-FC52-08NA28302 with the U.S. Department of Energy (DOE). This annual report summarizes progress in inertial fusion research at the Laboratory for Laser Energetics (LLE) during the past fiscal year including work on the National Ignition Campaign (NIC). It also reports on LLE's progress on laboratory basic science research; laser, optical materials, and advanced technology development; operation of OMEGA and OMEGA EP for the NIC and high-energy density (HED) campaigns, the National Laser Users Facility (NLUF), and for other external users; andmore » programs focusing on the education of high school, undergraduate, and graduate students during the year.« less
In vitro Studies of Sandfly Fever Viruses and Their Potential Significance for Vaccine Development.
1981-02-01
34 - "’: / AD In vitro Studies of Sandfly Fever Viruses and Their Potential Significance for Vaccine Development Annual Progress Report by CO Jonathan F. Smith...Significance for Vaccine 1 gR1 Development 6 WPW"a EOTHmaei AUTHOV&PSI CONTRACt OR GRANT NUMSERWa Jonahan . Smth, h.D.DAMD-17-78-C-8056 P6EftJrPORim...antibodies, post-translational processing, Immunoprecipitation, antigen purification, In vitro translation, passive transfer, vaccines _26. AEISTRACTMO
Extreme ultraviolet and soft x-ray diagnostics of high-temperature plasmas. Annual progress report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Moos, H W; Armstrong, L Jr
1980-01-01
The work performed from mid-January 1979 through 1980 is described. EUV diagnostic studies have been performed at the Alcator A and C Tokamaks, and on TMX. A toroidal asymmetry has been found in the low density phase of Alcator A. The confinement time of impurities has been measured on Alcator A. Impurity concentrations in the center cell of TMX have been studied using EUV spectroscopic techniques. A time resolving spectrograph with 1024 detector elements is essentially complete.
ERIC Educational Resources Information Center
DePaoli, Jennifer L.; Balfanz, Robert; Bridgeland, John
2016-01-01
The nation has achieved an 82.3 percent high school graduation rate--a record high. Graduation rates rose for all student subgroups, and the number of low-graduation-rate high schools and students enrolled in them dropped again, indicating that progress has had far-reaching benefits for all students. This report is the first to analyze 2014…
ERIC Educational Resources Information Center
Balfanz, Robert; Bridgeland, John M.; Fox, Joanna Hornig; Moore, Laura A.
2011-01-01
America continues to make progress in meeting its high school dropout challenge. Leaders in education, government, nonprofits and business have awakened to the individual, social and economic costs of the dropout crisis and are working together to solve it. This year, all states, districts, and schools are required by law to calculate high school…
Department of Clinical Investigation Annual Research Progress Report, Fiscal Year 1984. Volume 1,
1984-10-01
on a low dosage of medication . Technical Approach: None. Progress: The placebo has not been received from the company. Since the drug company...determine the effect of high dose Ar-C intensification therapy on the -. incidence of CNS relapse. - Technical Approach: All patients with a new...Enrolled to Date: 7 Date of Periodic Review Results Objective(s): To determine the incidence of
USAARL Annual Progress Report Fiscal Year 2012
2013-04-01
analyzed. A technical report is currently in progress. A research project entitled “Clinical Assessment of the Noise Immune Stethoscope ” evaluated the...noise immune stethoscope (NIS), a dual mode electronic and Doppler device, at Madigan Army Medical Center. Insight from the evaluations, data...Immune Stethoscope aboard a U.S. Navy Carrier. (Report No. 2012-02). Fort Rucker, AL: U.S. Army Aeromedical Research Laboratory. Gordon, E., & Reeves
ERIC Educational Resources Information Center
Balfanz, Robert; Bridgeland, John M.; Bruce, Mary; Fox, Joanna Hornig
2012-01-01
In 2010, the authors shared a Civic Marshall Plan to create a Grad Nation. Through that first report and subsequent update, they saw hopeful signs of progress in boosting high school graduation rates in communities across the country. This 2012 report shows that high school graduation rates continue to improve nationally and across many states and…
ERIC Educational Resources Information Center
Palacios, Moses; Casserly, Michael; Corcoran, Amanda; Hart, Ray; Simon, Candace; Uzzell, Renata
2014-01-01
Three years ago, the "Council of the Great City Schools" embarked on a multi-year initiative to help its member school districts implement the Common Core State Standards (CCSS). Part of this initiative involves annual surveys of progress urban public school districts were making in implementing the CCSS. With the support of the Bill…
Gröttrup, Bernd; May, Caroline; Meyer, Helmut E; Grinberg, Lea T; Park, Young Mok
2013-01-01
The HUPO Brain Proteome Project (HUPO BPP) held its 18(th) workshop in Boston, USA, September 12(th) 2012 during the HUPO 11th Annual Word Congress. The focus was on the progress on the Human Brain Proteome Atlas as well as ideas, strategies and methodological aspects. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Progress in the application of landform analysis in studies of semiarid erosion
Schumm, Stanley Alfred; Hadley, R.F.
1961-01-01
The analysis of topographic and hydrologic data gathered during studies of erosion in semiarid areas of Western United States show the following relation: (a) Mean annual sediment yield from small drainage basins is related to a ratio of basin relief to length; (b) mean annual runoff from small drainage basins is related to drainage density; (c) mean annual sediment yield per unit area decreases with increase in drainage area; (d) the form of some convex hill slopes is related to surficial creep; (e) asymmetry of drainage basins, including differences in hill-slope erosion and drainage density, is related to microclimatic variations on slopes of diverse exposure; .(f) the cutting of discontinuous gullies is closely related to steepening by deposition of the semiarid valley floor; (g) aggradation in ephemeral streams seems to be most prevalent in reaches where the ratio of contributing drainage area to channel length is relatively small; and (h) streamchannel shape, expressed as a width-depth ratio, is related to the percentage of silt-clay in bed and bank alluvium. The above relations cannot be detected without measurement of terrain characteristics. They further indicate the importance of quantitative terrain analysis in studies of erosion.
A Shared Commitment to the Cancer Moonshot
At the AACR annual meeting, Vice President Biden spoke about the National Cancer Moonshot Initiative and the critical role the entire research community will play in accelerating progress against cancer.
DOE Office of Scientific and Technical Information (OSTI.GOV)
McFadden, T.; Jenkins, T.; Collins, C.
1977-12-01
A study was initiated in 1975 to evaluate the fate and effects of crude oil spilled on a taiga-covered permafrost site in Alaska. During this second year of the study the logistical portion of the experiments was completed with a spill of hot Prudhoe Bay crude oil in July 1976. This spill was compared with one that took place in February 1976 (reported upon in the first annual progress report). Studies on the differences in the fate of the oil, its effects on the permafrost, and its impact on the biological communities were continued and expanded. Oil moved downslope atmore » a much faster rate during the summer spill than during the winter spill. In the winter the oil cooled and pooled rapidly. The summer spill covered approximately one-third more surface area than did the winter spill in the final configuration, even though the two spills were of almost identical volume. Increases in microbial populations and activities during the months following the spill were evident. Increased counts of bacteria, yeasts, denitrifying bacteria, and petroleum-degrading bacteria following the oil spills were particularly evident. Analysis of the oil's decomposition using gas chromatography techniques indicated that the low molecular weight fractions, methane and ethane, were lost almost immediately after the spill in each case.« less
ERIC Educational Resources Information Center
DePaoli, Jennifer L.; Fox, Joanna Hornig; Ingram, Erin S.; Maushard, Mary; Bridgeland, John M.; Balfanz, Robert
2015-01-01
In 2013, the national high school graduation rate hit a record high of 81.4 percent, and for the third year in a row, the nation remained on pace to meet the 90 percent goal by the Class of 2020. This sixth annual update on America's high school dropout challenge shows that these gains have been made possible by raising graduation rates for…
U.S. Army Aeromedical Research Laboratory Annual Progress Report Fiscal Year 2010
2011-03-01
S. (2010). Epidermal growth factor receptor transactivation by the cannabinoid receptor (CB1) and transient receptor potential vanilloid 1 ( TRPV1 ...induced by TRPV1 in human corneal epithelial cells. Proceedings of the Association for Research in Vision and Ophthalmology Annual Meeting, 5899/A94...presented “Novel TRPV1 -linked cell signaling pathways mediating inflammatory responses and wound healing in human corneal epithelial cells” at the Fouth
Department of Clinical Investigation Annual Research Progress Report.
1995-09-30
20th Annual Uniformed Services Fractures ?. Academy of Family Physicians, San Diego, USA, April 95. DeWeber K Factors Associated With Physicians’s USAFP...Resonance Mammography (MRM): A Promising 313 #94/159 Application for Fat Suppression by Phase Unwrapping in the 3-Point-Dixon Method Makuch RS 0...Isotonic Saline, Purified Water, and 378 #95/082 Dilute Hypochlorite Solution on the Rates of Infection and Tissue Response in Open Fractures of a
ERIC Educational Resources Information Center
Balfanz, Robert; Bridgeland, John M.; Bruce, Mary; Fox, Joanna Hornig
2013-01-01
This fourth annual update on America's high school dropout crisis shows that for the first time the nation is on track to meet the goal of a 90 percent high school graduation rate by the Class of 2020--if the pace of improvement from 2006 to 2010 is sustained over the next 10 years. The greatest gains have occurred for the students of color and…
The growth of government annual budget through taxes collection
NASA Astrophysics Data System (ADS)
Maiga, Sekou; Xu, Feng Ju
2017-09-01
In this case study we examine the relationship between the collection of taxes and the growth of government annual revenues (case of republic of Mali). Taxation is the most important source of revenue for modern governments, typically accounting for ninety percent or more of their income, Taxes revenues has contributed a big chunk of funds to the Malian Treasury, about 40%, with our focus being on the years (2012-2017). The primary economic goals of developing countries are to increase the rate of economic growth and hence per capita income, which leads to a higher standard of living. Government needs money to be able to execute its social obligations to the public and these social obligations include but not limited to the provision of infrastructure and social services. Progressive tax rate can be employed to achieve equitable distribution of resources. After economic modeling and estimation, we realized that there is a positive correlation between taxes collection changes and the government annual revenue.
Visitors or visits? An examination of zoo visitor numbers using the case study of Australia.
Smith, Liam
2013-01-01
Usually cited in reference to the potential reach of zoo education, one of the popular figures for global zoo visitation is that 600 million people visit zoos annually. However, this number needs clarification on two fronts. First, there are many zoo visitors who are not included in the calculation because they visited a zoo that was not included in the count. Second, it does not take into consideration the people visit either the same or different zoos more than once annually. Using data collected from several sources, including zoo visitors themselves, this article focuses on one country--Australia--that contributes 15.6 million to the visitation total, and contends that the correct number of unique annual zoo visitors to Australian zoos is likely to be between 8 and 10 million. However, rather than suggesting an overemphasis on the potential of zoos for educating visitors, having regular repeat visitors represents a distinct advantage for zoos, allowing for progressive education opportunities. © 2012 Wiley Periodicals, Inc.
Progression of Alzheimer disease as measured by Clinical Dementia Rating sum of boxes scores
Williams, Monique M.; Storandt, Martha; Roe, Catherine M.; Morris, John C.
2013-01-01
Background This study examined rates of dementia progression as ascertained by the Clinical Dementia Rating sum of boxes (CDR-SB) for symptomatic Alzheimer disease (sAD) and assessed participant characteristics as predictors of CDR-SB progression. Methods Participants (n = 792) were enrolled in longitudinal studies at an Alzheimer’s Disease Research Center, received a diagnosis of sAD with a global CDR of 0.5 (n = 466) or 1 (n = 326), and had at least one follow-up assessment. Progression in CDR-SB over time as a function of baseline global CDR was examined. Results A longitudinal increase (p<.0001) in CDR-SB was observed. The annual rate of change in CDR-SB scores was 1.43 (SE=.05) in the CDR 0.5 sample and 1.91 (SE=.07) in the CDR 1 sample. For participants followed from the beginning of the CDR stage, time to progression to a higher global CDR was longer for individuals who were CDR 0.5 (3.75 years; 95% CI 3.18-4.33) than those who were CDR 1 at baseline (2.98 years; 95%CI 2.75-3.22). In the total CDR 0.5 sample, the significant predictors of progression to the next global CDR stage (p<.01) were age at first sAD diagnosis and apolipoprotein E4 genotype. Conclusions The study findings are relevant to sAD clinical trial design and accurate, reliable ascertainment of the effect of disease-modifying treatments. PMID:22858530
14 CFR 91.875 - Annual progress reports.
Code of Federal Regulations, 2013 CFR
2013-01-01
...) AIR TRAFFIC AND GENERAL OPERATING RULES GENERAL OPERATING AND FLIGHT RULES Operating Noise Limits § 91... report, that specific planning data be considered proprietary. (e) If an operator's actions during any...
14 CFR 91.875 - Annual progress reports.
Code of Federal Regulations, 2011 CFR
2011-01-01
...) AIR TRAFFIC AND GENERAL OPERATING RULES GENERAL OPERATING AND FLIGHT RULES Operating Noise Limits § 91... report, that specific planning data be considered proprietary. (e) If an operator's actions during any...
14 CFR 91.875 - Annual progress reports.
Code of Federal Regulations, 2010 CFR
2010-01-01
...) AIR TRAFFIC AND GENERAL OPERATING RULES GENERAL OPERATING AND FLIGHT RULES Operating Noise Limits § 91... report, that specific planning data be considered proprietary. (e) If an operator's actions during any...
14 CFR 91.875 - Annual progress reports.
Code of Federal Regulations, 2012 CFR
2012-01-01
...) AIR TRAFFIC AND GENERAL OPERATING RULES GENERAL OPERATING AND FLIGHT RULES Operating Noise Limits § 91... report, that specific planning data be considered proprietary. (e) If an operator's actions during any...
14 CFR 91.875 - Annual progress reports.
Code of Federal Regulations, 2014 CFR
2014-01-01
...) AIR TRAFFIC AND GENERAL OPERATING RULES GENERAL OPERATING AND FLIGHT RULES Operating Noise Limits § 91... report, that specific planning data be considered proprietary. (e) If an operator's actions during any...
78 FR 50075 - Statewide Communication Interoperability Plan Template and Annual Progress Report
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-16
... of Cybersecurity and Communications (CS&C), Office of Emergency Communications (OEC), will submit the... Directorate, Office of Cybersecurity and Communications, Office of Emergency Communications. Title: Statewide...
Chronic kidney disease among children in Guatemala.
Cerón, Alejandro; Fort, Meredith P; Morine, Chris M; Lou-Meda, Randall
2014-12-01
To describe the distribution of pediatric chronic kidney disease (CKD) in Guatemala, estimate incidence and prevalence of pediatric end-stage renal disease (ESRD), and estimate time to progress to ESRD. This study analyzed the registry of the only pediatric nephrology center in Guatemala, from 2004-2013. Incidence and prevalence were calculated for annual periods. Moran's index for spatial autocorrelation was used to determine significance of geographic distribution of incidence. Time to progress to ESRD and associated risk factors were calculated with multivariate Cox regression. Of 1 545 patients from birth to less than 20 years of age, 432 had chronic renal failure (CRF). Prevalence and incidence of ESRD were 4.9 and 4.6 per million age-related population, respectively. Incidence was higher for the Pacific coast and Guatemala City. The cause of CRF was undetermined in 43% of patients. Average time to progress to ESRD was 21.9 months; factors associated with progression were: older age, diagnosis of glomerulopathies, and advanced-stage CKD at consultation. Prevalence and incidence of ESRD in Guatemala are lower than in other countries. This may reflect poor access to diagnosis. Areas with higher incidence and large proportion of CKD of undetermined cause are compatible with other studies from the geographic subregion. Findings on progression to ESRD may reflect delayed referral.
Tee, James J L; Yang, Yesa; Kalitzeos, Angelos; Webster, Andrew; Bainbridge, James; Weleber, Richard G; Michaelides, Michel
2018-05-01
To characterize bilateral visual function, interocular variability and progression by using static perimetry-derived volumetric and pointwise metrics in subjects with retinitis pigmentosa associated with mutations in the retinitis pigmentosa GTPase regulator (RPGR) gene. This was a prospective longitudinal observational study of 47 genetically confirmed subjects. Visual function was assessed with ETDRS and Pelli-Robson charts; and Octopus 900 static perimetry using a customized, radially oriented 185-point grid. Three-dimensional hill-of-vision topographic models were produced and interrogated with the Visual Field Modeling and Analysis software to obtain three volumetric metrics: VTotal, V30, and V5. These were analyzed together with Octopus mean sensitivity values. Interocular differences were assessed with the Bland-Altman method. Metric-specific exponential decline rates were calculated. Baseline symmetry was demonstrated by relative interocular difference values of 1% for VTotal and 8% with V30. Degree of symmetry varied between subjects and was quantified with the subject percentage interocular difference (SPID). SPID was 16% for VTotal and 17% for V30. Interocular symmetry in progression was greatest when quantified by VTotal and V30, with 73% and 64% of subjects possessing interocular rate differences smaller in magnitude than respective annual progression rates. Functional decline was evident with increasing age. An overall annual exponential decline of 6% was evident with both VTotal and V30. In general, good interocular symmetry exists; however, there was both variation between subjects and with the use of various metrics. Our findings will guide patient selection and design of RPGR treatment trials, and provide clinicians with specific prognostic information to offer patients affected by this condition.
Kshirsagar, Nilima A; Gogtay, N J; Garg, B S; Deshmukh, P R; Rajgor, D D; Kadam, V S; Thakur, P A; Gupta, A; Ingole, N S; Lazdins-Helds, J K
2017-10-01
Lymphatic filariasis (LF) affects 73 countries, causes morbidity and impedes socioeconomic development. We had found no difference in safety and micro (Mf) and macro filarial action of single-dose diethylcarbamazine (DEC) and DEC + albendazole (ABZ) in an F01 study done in India (year 2000). There was a programmatic need to evaluate safety and efficacy of multiple annual treatments (F02). Subjects (155) from the F01 study, meeting inclusion-exclusion criteria, were enrolled in F02 and treated with further two annual doses of DEC or DEC + ABZ. Efficacy was evaluated for Mf positivity by peripheral smear (PS) and nucleopore (NP) filter, circulating filarial antigen (CFA) and filarial dance sign (FDS) positivity and Mf count at yearly follow-up. Safety was assessed for 5 days after drug administration. Total of 139 subjects evaluated for efficacy (69 DEC and 70 DEC + ABZ group). Mf positivity prevalence declined progressively by 95% (PS), 66% (NP), and 95% (PS) and 86% (NP); CFA positivity prevalence declined by 15% and 9%; FDS by 100% each; Mf count declined by 75.5 and 76.9% with three annual treatment of DEC and DEC + ABZ, respectively. Addition of ABZ did not show any advantage over DEC given as three annual rounds for LF. DEC and DEC + ABZ were well tolerated. There was no correlation between result of CFA and FDS, (both claimed to be indicative of adult worm). Analysis of published studies and our data indicate that macrofilaricidal effect of DEC/DEC + ABZ may be seen in children and not adults, with three or more annual dosing.
Estimate of the cost of multiple sclerosis in Spain by literature review.
Fernández, Oscar; Calleja-Hernández, Miguel Angel; Meca-Lallana, José; Oreja-Guevara, Celia; Polanco, Ana; Pérez-Alcántara, Ferran
2017-08-01
Multiple Sclerosis (MS) is a progressive disease leading to increasing disability and costs. A literature review was carried out to identify MS costs and to estimate its economic burden in Spain. Areas Covered: The public electronic databases PubMed, ScienceDirect and IBECS were consulted and a manual review of communications presented at related congresses was carried out. A total of 225 references were obtained, of which 43 were finally included in the study. Expert Commentary: Three major cost groups were identified: direct healthcare costs, direct non-healthcare costs and indirect costs. There is a direct relationship between disease progression and increased costs, mainly direct non-healthcare costs (greater need for informal care) and indirect costs (greater loss of productivity). The total cost associated with MS in Spain is €1,395 million per year, and that the mean annual cost per patient is €30,050. Beyond costs, a large impact on the quality of life of patients, with an annual loss of up to 13,000 quality-adjusted life years was also estimated. MS has a large economic impact on Spanish society and a significant impact on the quality of life of patients.
Frequency of Evidence-Based Screening for Retinopathy in Type 1 Diabetes.
Nathan, David M; Bebu, Ionut; Hainsworth, Dean; Klein, Ronald; Tamborlane, William; Lorenzi, Gayle; Gubitosi-Klug, Rose; Lachin, John M
2017-04-20
In patients who have had type 1 diabetes for 5 years, current recommendations regarding screening for diabetic retinopathy include annual dilated retinal examinations to detect proliferative retinopathy or clinically significant macular edema, both of which require timely intervention to preserve vision. During 30 years of the Diabetes Control and Complications Trial (DCCT) and its longitudinal follow-up Epidemiology of Diabetes Interventions and Complications (EDIC) study, retinal photography was performed at intervals of 6 months to 4 years. We used retinal photographs from the DCCT/EDIC study to develop a rational screening frequency for retinopathy. Markov modeling was used to determine the likelihood of progression to proliferative diabetic retinopathy or clinically significant macular edema in patients with various initial retinopathy levels (no retinopathy or mild, moderate, or severe nonproliferative diabetic retinopathy). The models included recognized risk factors for progression of retinopathy. Overall, the probability of progression to proliferative diabetic retinopathy or clinically significant macular edema was limited to approximately 5% between retinal screening examinations at 4 years among patients who had no retinopathy, 3 years among those with mild retinopathy, 6 months among those with moderate retinopathy, and 3 months among those with severe nonproliferative diabetic retinopathy. The risk of progression was also closely related to mean glycated hemoglobin levels. The risk of progression from no retinopathy to proliferative diabetic retinopathy or clinically significant macular edema was 1.0% over 5 years among patients with a glycated hemoglobin level of 6%, as compared with 4.3% over 3 years among patients with a glycated hemoglobin level of 10%. Over a 20-year period, the frequency of eye examinations was 58% lower with our practical, evidence-based schedule than with routine annual examinations, which resulted in substantial cost savings. Our model for establishing an individualized schedule for retinopathy screening on the basis of the patient's current state of retinopathy and glycated hemoglobin level reduced the frequency of eye examinations without delaying the diagnosis of clinically significant disease. (Funded by the National Institute of Diabetes and Digestive and Kidney Diseases and others; DCCT/EDIC ClinicalTrials.gov numbers, NCT00360893 and NCT00360815 .).
NASA Astrophysics Data System (ADS)
Mousam, Aneela; Maggioni, Viviana; Delamater, Paul L.; Quispe, Antonio M.
2017-10-01
Between 2001 and 2010 significant progress was made towards reducing the number of malaria cases in Peru; however, the country saw an increase between 2011 and 2015. This work attempts to uncover the associations among various climatic and environmental variables and the annual malaria parasite incidence in the Peruvian region of Loreto. A Multilevel Mixed-effects Poisson Regression model is employed, focusing on the 2009-2013 period, when trends in malaria incidence shifted from decreasing to increasing. The results indicate that variations in elevation (β = 0.78; 95% confidence interval (CI), 0.75-0.81), soil moisture (β = 0.0021; 95% CI, 0.0019-0.0022), rainfall (β = 0.59; 95% CI, 0.56-0.61), and normalized difference vegetation index (β = 2.13; 95% CI, 1.83-2.43) is associated with higher annual parasite incidence, whereas an increase in temperature (β = -0.0043; 95% CI, - 0.0044- 0.0041) is associated with a lower annual parasite incidence. The results from this study are particularly useful for healthcare workers in Loreto and have the potential of being integrated within malaria elimination plans.
The U.S. EPA's Green Power Partnership is a voluntary program designed to reduce the environmental impact of electricity generation by promoting renewable energy. EPA evaluates partnership metrics annually to determine progress toward programmatic goals.
US Army Institute of Surgical Research Annual Research Progress Report for Fiscal Year 1984.
1984-10-01
the product of the individual and collaborative scientific activities of the Institute’s professionals made possible by the efforts of all members... activities on the process of medical research with the resultant blurring of the distinction between the process and the product. Extensive administrative...professional activities , regulate human studies, and restrict the use of animals in research, but to what effect? Benefits of such administrative
Walter Reed Army Medical Center, Washington, D. C. Annual Progress Report FY-89. Volume 2. Part 2
1990-01-02
Patterns of Cerebral Blood Flow Determined by Iodoamphetamine SPECT in Sjogren’s Syndrome and Systemic Lupus Erythematosus: A Pilot Study KEYWORDS: SPECT...scanning in patients with Sjogren’s Syndrome and SLE. To identify possible regional defects in cerebral blood flow and correlate these defects with the...in animals reveals myelosuppression, lymphoid atrophy, * hemorrhagic enterocolitis, renal tubular necrosis, and cochlear damage, as well as some
Sujirakul, Tharikarn; Lin, Michael K.; Duong, Jimmy; Wei, Ying; Lopez-Pintado, Sara; Tsang, Stephen H.
2015-01-01
Purpose To determine the rate of progression and optimal follow up time in patients with advanced stage retinitis pigmentosa (RP) comparing the use of fundus autofluorescence imaging and spectral domain optical coherence tomography. Design Retrospective analysis of progression rate. Methods Longitudinal imaging follow up in 71 patients with retinitis pigmentosa was studied using the main outcome measurements of hyperautofluoresent ring horizontal diameter and vertical diameter along with ellipsoid zone line width from spectral domain optical coherence tomography. Test-retest reliability and the rate of progression were calculated. The interaction between the progression rates was tested for sex, age, mode of inheritance, and baseline measurement size. Symmetry of left and right eye progression rate was also tested. Results Significant progression was observed in >75% of patients during the 2 year mean follow up. The mean annual progression rates of ellipsoid zone line, and hyperautofluorescent ring horizontal diameter and vertical diameter were 0.45° (4.9%), 0.51° (4.1%), and 0.42° (4.0%), respectively. The e llipsoid zone line width, and hyperautofluorescent ring horizontal diameter and vertical diameter had low test-retest variabilities of 8.9%, 9.5% and 9.6%, respectively. This study is the first to demonstrate asymmetrical structural progression rate between right and left eye, which was found in 19% of patients. The rate of progression was significantly slower as the disease approached the fovea, supporting the theory that RP progresses in an exponential fashion. No significant interaction between progression rate and patient age, sex, or mode of inheritance was observed. Conclusions Fundus autofluorescence and optical coherence tomography detect progression in patients with RP reliably and with strong correlation. These parameters may be useful alongside functional assessments as the outcome measurements for future therapeutic trials. Follow-up at 1 year intervals should be adequate to efficiently detect progression. PMID:26164827
DOE Office of Scientific and Technical Information (OSTI.GOV)
DEFIGH PRICE, C.
2000-09-25
Milestone M-45-09E of the Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement or TPA) [TPA 1996] requires submittal of an annual progress report on the development of waste tank leak detection, monitoring, and mitigation (LDMM) activities associated with the retrieval of waste from single-shell tanks (SSTs). This report details progress for fiscal year 2000, building on the current LDMM strategy and including discussion of technologies, applications, cost, schedule, and technical data. The report also includes discussion of demonstrations conducted and recommendations for additional testing. Tri-Party Agreement Milestones M-45-08A and M-45-08B required design and demonstration of LDMM systems for initialmore » retrieval of SST waste. These specific milestones have recently been deleted as part of the M-45-00A change package. Future LDMM development work has been incorporated into specific technology demonstration milestones and SST waste retrieval milestones in the M-45-03 and M-45-05 milestone series.« less
Mikhailov, Alexei; Yajima, Aya; Mbabazi, PS; Gabrielli, Albis F.; Montresor, Antonio; Engels, Dirk
2017-01-01
The integration of vertical control programmes of neglected tropical diseases (NTDs) aims at containing operational cost, simplifies the application of the control measures and extends the intervention coverage. The Preventive Chemotherapy and Transmission Control (PCT) Databank was established by the World Health Organization to facilitate the sharing of data among the different partners involved in control activities and collects and compiles historical and current information on disease-specific epidemiological situation, the geographical overlapping of NTDs and the progress of control activities in all the NTD-endemic countries. The summary of country-specific epidemiological maps and the progress of control activities is available online as the online PCT Databank and Country Profiles. The annual progress of preventive chemotherapy (PC) interventions targeting at specific NTDs is also annually reported in the Weekly Epidemiological Record (WER). In this paper, we elucidated the methodology of data collection, compilation and mapping to establish the PCT Databank and presented the key features of the associated three online outputs, i.e. the online PCT Databank, the Country Profile and the WER. PMID:22357399
Analytical Chemistry Division annual progress report for period ending December 31, 1985
DOE Office of Scientific and Technical Information (OSTI.GOV)
Shultz, W.D.
1986-05-01
Progress reports are presented for the four major sections of the division: analytical spectroscopy, radioactive materials laboratories, inorganic chemistry, and organic chemistry. A brief discussion of the division's role in the Laboratory's Environmental Restoration and Facilities Upgrade is given. Information about quality assurance and safety programs is presented, along with a tabulation of analyses rendered. Publications, oral presentations, professional activities, educational programs, and seminars are cited.
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
1958-10-31
The progress and trends of research are presented along with a description of operational, service, end administrative activities. Some scientific and technical details are given on research programs in the physical sciences, life sciences, and engineering, however, more complete technical information is available in quarterly progress reports, BNL technical reports, and scientific and technical periodicals. A bibliography of these publications is appended. (For preceding period see BNL-426.) (D.E.B.)
Annual Progress Report FY-92. Volume 2
1992-01-01
OBJECTIVE To measure the effect of methotrexate on interleukin-l ( IL - 1 ) induced ICAN-l expression in cultured human fibroblasts and adenocarcinoma cells...SUMMARY SHEET TITLE: Effect of IL - 1 on Glucocorticoid Inhibition of Wound Healing KEYWORDS: IL - 1 , wound healing PRINCIPAL INVESTIGATOR: Schoenfeld, Phil CPT...PROGRESS Cultured cells were incubated with IL -l to stimulate ICAM-l expression. In general, the cells responded well. ICAM- 1 was readily detectable
ERIC Educational Resources Information Center
Blank, Rolf K.
2011-01-01
A critical state-level indicator of progress in public education is student achievement annual performance and change over time. The Council of Chief State School Officers (CCSSO) has been very active in tracking and reporting on student achievement results and using state assessment scores and other data to analyze achievement trends. A central…
Appel, Lawrence J.; Wright, Jackson T.; Greene, Tom; Kusek, John W.; Lewis, Julia B.; Wang, Xuelei; Lipkowitz, Michael S.; Norris, Keith C.; Bakris, George L.; Rahman, Mahboob; Contreras, Gabriel; Rostand, Stephen G.; Kopple, Joel D.; Gabbai, Francis B.; Schulman, Gerald I.; Gassman, Jennifer J.; Charleston, Jeanne; Agodoa, Lawrence Y.
2013-01-01
Background Antihypertensive drugs that block the renin-angiotensin system (angiotensin-converting enzyme inhibitors [ACEIs] or angiotensin receptor blockers) are recommended for patients with chronic kidney disease (CKD). A low blood pressure (BP) goal (BP, <130/80 mm Hg) is also recommended. The objective of this study was to determine the long-term effects of currently recommended BP therapy in 1094 African Americans with hypertensive CKD. Methods Multicenter cohort study following a randomized trial. Participants were 1094 African Americans with hypertensive renal disease (glomerular filtration rate, 20–65 mL/min/1.73 m2). Following a 3×2-factorial trial (1995–2001) that tested 3 drugs used as initial antihypertensive therapy (ACEIs, calcium channel blockers, and β-blockers) and 2 levels of BP control (usual and low), we conducted a cohort study (2002–2007) in which participants were treated with ACEIs to a BP lower than 130/80 mm Hg. The outcome measures were a composite of doubling of the serum creatinine level, end-stage renal disease, or death. Results During each year of the cohort study, the annual use of an ACEI or an angiotensin receptor blocker ranged from 83.7% to 89.0% (vs 38.5% to 49.8% during the trial). The mean BP in the cohort study was 133/78 mm Hg (vs 136/82 mm Hg in the trial). Overall, 567 participants experienced the primary outcome; the 10-year cumulative incidence rate was 53.9%. Of 576 participants with at least 7 years of follow-up, 33.5% experienced a slow decline in kidney function (mean annual decline in the estimated glomerular filtration rate, <1 mL/min/1.73 m2). Conclusion Despite the benefits of renin-angiotensin system–blocking therapy on CKD progression, most African Americans with hypertensive CKD who are treated with currently recommended BP therapy continue to progress during the long term. PMID:18443258
Pesticide Reregistration Performance Measures and Goals 1997-2008
Find past annual reports that were submitted, as required by the Federal Insecticide Fungicide and Rodenticide Act (as amended by FQPA), describing the agency's progress in meeting goals for reregistration and tolerance assessment.
Solid State Division annual progress report for period ending December 31, 1975
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wilkinson, M.K.; Young, F.W. Jr.
1976-05-01
Research activities are reported in programs on theoretical solid state physics, physical properties of solids, radiation effects in metals, neutron scattering, research materials, and isotope research materials. (JRD)
Green Power Partnership Program Success Metrics
The U.S. EPA's Green Power Partnership is a voluntary program designed to reduce the environmental impact of electricity generation by promoting renewable energy. EPA evaluates partnership metrics annually to determine progress toward programmatic goals.
Meetings | Informatics Technology for Cancer Research (ITCR)
ITCR Annual Meetings Meetings with ITCR Principal Investigators (PIs) and program staff to discuss progress, facilitate collaborations and solicit feedback from program participants. Meeting agendas, notes and presentations are available through the links below.
7 CFR 3405.19 - Monitoring progress of funded projects.
Code of Federal Regulations, 2010 CFR
2010-01-01
... the first year of the project and annually thereafter during the life of the grant. Generally, the... agricultural sciences higher education system; and data on project personnel and beneficiaries. The Final...
Benchmarking of OEM Hybrid Electric Vehicles at NREL: Milestone Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kelly, K. J.; Rajagopalan, A.
2001-10-26
A milestone report that describes the NREL's progress and activities related to the DOE FY2001 Annual Operating Plan milestone entitled ''Benchmark 2 new production or pre-production hybrids with ADVISOR.''
7 CFR 3405.19 - Monitoring progress of funded projects.
Code of Federal Regulations, 2011 CFR
2011-01-01
... thereafter during the life of the grant. Generally, the Annual Performance Reports should include a summary... director(s), the institution, and the food and agricultural sciences higher education system; and data on...
7 CFR 3405.19 - Monitoring progress of funded projects.
Code of Federal Regulations, 2014 CFR
2014-01-01
... thereafter during the life of the grant. Generally, the Annual Performance Reports should include a summary... director(s), the institution, and the food and agricultural sciences higher education system; and data on...
7 CFR 3405.19 - Monitoring progress of funded projects.
Code of Federal Regulations, 2013 CFR
2013-01-01
... thereafter during the life of the grant. Generally, the Annual Performance Reports should include a summary... director(s), the institution, and the food and agricultural sciences higher education system; and data on...
7 CFR 3405.19 - Monitoring progress of funded projects.
Code of Federal Regulations, 2012 CFR
2012-01-01
... thereafter during the life of the grant. Generally, the Annual Performance Reports should include a summary... director(s), the institution, and the food and agricultural sciences higher education system; and data on...
78 FR 18597 - Proposed Data Collections Submitted for Public Comment and Recommendations
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-27
... collection techniques or other forms of information technology. Written comments should be received within 60... Annual Report that describes activities, progress toward objectives, and Success Stories which highlight...
Deribe, Kebede; Brooker, Simon J; Pullan, Rachel L; Hailu, Asrat; Enquselassie, Fikre; Reithinger, Richard; Newport, Melanie; Davey, Gail
2013-01-01
An up-to-date and reliable map of podoconiosis is needed to design geographically targeted and cost-effective intervention in Ethiopia. Identifying the ecological correlates of the distribution of podoconiosis is the first step for distribution and risk maps. The objective of this study was to investigate the spatial distribution and ecological correlates of podoconiosis using historical and contemporary survey data. Data on the observed prevalence of podoconiosis were abstracted from published and unpublished literature into a standardized database, according to strict inclusion and exclusion criteria. In total, 10 studies conducted between 1969 and 2012 were included, and data were available for 401,674 individuals older than 15 years of age from 229 locations. A range of high resolution environmental factors were investigated to determine their association with podoconiosis prevalence, using logistic regression. The prevalence of podoconiosis in Ethiopia was estimated at 3.4% (95% CI 3.3%-3.4%) with marked regional variation. We identified significant associations between mean annual Land Surface Temperature (LST), mean annual precipitation, topography of the land and fine soil texture and high prevalence of podoconiosis. The derived maps indicate both widespread occurrence of podoconiosis and a marked variability in prevalence of podoconiosis, with prevalence typically highest at altitudes >1500 m above sea level (masl), with >1500 mm annual rainfall and mean annual LST of 19-21°C. No (or very little) podoconiosis occurred at altitudes <1225 masl, with annual rainfall <900 mm, and mean annual LST of >24°C. Podoconiosis remains a public health problem in Ethiopia over considerable areas of the country, but exhibits marked geographical variation associated in part with key environmental factors. This is work in progress and the results presented here will be refined in future work.
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
2001-03-01
This Annual Report to the Congress describes the Department of Energy's activities in response to formal recommendations and other interactions with the Defense Nuclear Facilities Safety Board. During 2000, the Department completed its implementation and proposed closure of one Board recommendation and completed all implementation plan milestones associated with two additional Board recommendations. Also in 2000, the Department formally accepted two new Board recommendations and developed implementation plans in response to those recommendations. The Department also made significant progress with a number of broad-based safety initiatives. These include initial implementation of integrated safety management at field sites and within headquartersmore » program offices, issuance of a nuclear safety rule, and continued progress on stabilizing excess nuclear materials to achieve significant risk reduction.« less
ERIC Educational Resources Information Center
Beard, J. Taylor; And Others
This report is part of a series from the Department of Energy on the use of solar energy in heating buildings. Described here is a new system for year around collection and storage of solar energy. This system has been operated at the University of Virginia for over a year. Composed of an underground hot water storage system and solar collection,…
Design and application of electromechanical actuators for deep space missions
NASA Technical Reports Server (NTRS)
Haskew, Tim A.; Wander, John
1993-01-01
The annual report Design and Application of Electromechanical Actuators for Deep Space Missions is presented. The reporting period is 16 Aug. 1992 to 15 Aug. 1993. However, the primary focus will be work performed since submission of our semi-annual progress report in Feb. 1993. Substantial progress was made. We currently feel confident in providing guidelines for motor and control strategy selection in electromechanical actuators to be used in thrust vector control (TVC) applications. A small portion was presented in the semi-annual report. At this point, we have implemented highly detailed simulations of various motor/drive systems. The primary motor candidates were the brushless dc machine, permanent magnet synchronous machine, and the induction machine. The primary control implementations were pulse width modulation and hysteresis current control. Each of the two control strategies were applied to each of the three motor choices. With either pulse width modulation or hysteresis current control, the induction machine was always vector controlled. A standard test position command sequence for system performance evaluation is defined. Currently, we are gathering all of the necessary data for formal presentation of the results. Briefly stated for TVC application, we feel that the brushless dc machine operating under PWM current control is the best option. Substantial details on the topic, with supporting simulation results, will be provided later, in the form of a technical paper prepared for submission and also in the next progress report with more detail than allowed for paper publication.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Felton, D.L.
1985-02-01
Research progress is reported in the following areas: (1) evaluation of possible health effects among nuclear workers; (2) dose-effect relationship studies of carcinogenesis from both nuclear materials and complex mixtures; (3) microbial mutagenesis studies with 6-aminochrysene and benzo(a)pyrene in coal-derived complex mixtures; and (4) a variety of studies relating to noncarcinogenic and nonmutagenic endpoints, including teratology, perinatal studies and studies to determine absorption, metabolism, and doses to critical tissues and organs of coal-derived mixtures and radionuclides. Items have been individually abstracted for the data base. (ACR)
Sanders, Chelsea; Behrens, Stephanie; Schwartz, Sarah; Wengreen, Heidi; Corcoran, Chris D.; Lyketsos, Constantine G.; Tschanz, JoAnn T.
2017-01-01
Nutritional status may be a modifiable factor in the progression of dementia. We examined the association of nutritional status and rate of cognitive and functional decline in a U.S. population-based sample. Study design was an observational longitudinal study with annual follow-ups up to 6 years of 292 persons with dementia (72% Alzheimer’s disease, 56% female) in Cache County, UT using the Mini-Mental State Exam (MMSE), Clinical Dementia Rating Sum of Boxes (CDR-sb), and modified Mini Nutritional Assessment (mMNA). mMNA scores declined by approximately 0.50 points/year, suggesting increasing risk for malnutrition. Lower mMNA score predicted faster rate of decline on the MMSE at earlier follow-up times, but slower decline at later follow-up times, whereas higher mMNA scores had the opposite pattern (mMNA by time β = 0.22, p = 0.017; mMNA by time2 β = −0.04, p = 0.04). Lower mMNA score was associated with greater impairment on the CDR-sb over the course of dementia (β = 0.35, p < 0.001). Assessment of malnutrition may be useful in predicting rates of progression in dementia and may provide a target for clinical intervention. PMID:26967207
Sanders, Chelsea; Behrens, Stephanie; Schwartz, Sarah; Wengreen, Heidi; Corcoran, Chris D; Lyketsos, Constantine G; Tschanz, JoAnn T
2016-02-27
Nutritional status may be a modifiable factor in the progression of dementia. We examined the association of nutritional status and rate of cognitive and functional decline in a U.S. population-based sample. Study design was an observational longitudinal study with annual follow-ups up to 6 years of 292 persons with dementia (72% Alzheimer's disease, 56% female) in Cache County, UT using the Mini-Mental State Exam (MMSE), Clinical Dementia Rating Sum of Boxes (CDR-sb), and modified Mini Nutritional Assessment (mMNA). mMNA scores declined by approximately 0.50 points/year, suggesting increasing risk for malnutrition. Lower mMNA score predicted faster rate of decline on the MMSE at earlier follow-up times, but slower decline at later follow-up times, whereas higher mMNA scores had the opposite pattern (mMNA by time β= 0.22, p = 0.017; mMNA by time2 β= -0.04, p = 0.04). Lower mMNA score was associated with greater impairment on the CDR-sb over the course of dementia (β= 0.35, p < 0.001). Assessment of malnutrition may be useful in predicting rates of progression in dementia and may provide a target for clinical intervention.
Carpenter, Lewis; Norton, Sam; Nikiphorou, Elena; Jayakumar, Keeranur; McWilliams, Daniel F; Rennie, Kirsten L; Dixey, Josh; Kiely, Patrick; Walsh, David Andrew; Young, Adam
2017-12-01
To assess the 5-year progression of erosions and joint space narrowing (JSN) and their associations with rheumatoid factor (RF) status in 2 large, multicenter, early rheumatoid arthritis cohorts, spanning 25 years. Radiographic joint damage was recorded using the Sharp/van der Heijde (SHS) method in the Early Rheumatoid Arthritis Study (ERAS), 1986-2001, and the Early Rheumatoid Arthritis Network (ERAN), 2002-2013. Mixed-effects negative binomial regression estimated changes in radiographic damage over 5 years, including erosions and JSN, separately. RF, along with age, sex, and baseline markers of disease activity were controlled for. A total of 1,216 patients from ERAS and 446 from ERAN had radiographic data. Compared to ERAS, ERAN patients had a lower mean total SHS score at baseline (ERAN 6.2 versus ERAS 10.5; P < 0.001) and mean annual rate of change (ERAN 2.5 per year versus ERAS 6.9 per year; P < 0.001). Seventy-four percent of ERAS and 27% of ERAN patients progressed ≥5 units. Lower scores at baseline in ERAN were largely driven by reductions in JSN (ERAS 3.9 versus ERAN 1.2; P < 0.001), along with erosions (ERAS 1.9 versus ERAN 0.8; P < 0.001). RF was associated with greater progression in each cohort, but the absolute difference in mean annual rate of change for RF-positive patients was substantially higher for ERAS (RF positive 8.6 versus RF negative 5.1; P < 0.001), relative to ERAN (RF positive 2.0 versus RF negative 1.9; P = 0.855). Radiographic progression was shown to be significantly reduced between the 2 cohorts, and was associated with lower baseline damage and other factors, including changes in early disease-modifying antirheumatic drug use. The impact of RF status as a prognostic marker of clinically meaningful change in radiographic progression has markedly diminished in the context of more modern treatment. © 2017, American College of Rheumatology.
Antidopaminergic Medication is Associated with More Rapidly Progressive Huntington's Disease.
Tedroff, Joakim; Waters, Susanna; Barker, Roger A; Roos, Raymund; Squitieri, Ferdinando
2015-01-01
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder leading to progressive motor, cognitive and functional decline. Antidopaminergic medications (ADMs) are frequently used to treat chorea and behavioural disturbances in HD. We aimed to assess how the use of such medications was associated with the severity and progression of the motor aspects of the condition, given that there have been concerns that such drugs may actually promote neurological deterioration. Using multiple linear regression, supplemented by principal component analysis to explore the overall correlation patterns and help identify relevant covariates, we assessed severity and progression of motor symptoms and functional decline in 651 manifest patients from the REGISTRY cohort followed for two years. ADM treated versus non-treated subjects were compared with respect to motor impairment at baseline and progression rate by means of multiple regression, adjusting for CAG-repeat and age. Patients treated with ADMs had significantly worse motor scores with greater functional disability at their first visit. They also showed a higher annual rate of progression of motor signs and disability over the next two years. In particular the rate of progression for oculomotor symptoms and bradykinesia was markedly increased whereas the rate of progression of chorea and dystonia was similar for ADM and drug naïve patients. These differences in clinical severity and progression could not be explained by differences in disease burden, duration of disease or other possible prognostic factors. The results from this analysis suggest ADM treatment is associated with more advanced and rapidly progressing HD although whether these drugs are causative in driving this progression requires further, prospective studies.
Midwest Transportation Consortium annual progress report : October 2001.
DOT National Transportation Integrated Search
2001-10-01
From the Director: Transportation assets are tremendously important from the perspective the performance of our national, : state, and regional economies. Few people comprehend the great impact it has on the overall economy. : Literally trillions of ...
10 CFR 603.885 - Updated program plans and budgets.
Code of Federal Regulations, 2011 CFR
2011-01-01
... program plans and budgets. In addition to reports on progress to date, a TIA may include a provision requiring the recipient to annually prepare an updated technical plan for future conduct of the research...
Climate Ready Estuaries Progress Reports
Climate Ready Estuaries has supported adaptation activities in National Estuary Programs since 2008. In 2012, the program partnered with 23 NEPs, completed a pilot project with water utilities, and held workshops. Download annual reports from 2009-2012.
42 CFR 505.17 - Reporting requirements for meeting the conditions for loan forgiveness.
Code of Federal Regulations, 2011 CFR
2011-10-01
..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) HEALTH CARE INFRASTRUCTURE IMPROVEMENT PROGRAM... measure used to track the qualifying hospital's progress in meeting its plan goals. (b) Review of annual...
42 CFR 505.17 - Reporting requirements for meeting the conditions for loan forgiveness.
Code of Federal Regulations, 2010 CFR
2010-10-01
..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) HEALTH CARE INFRASTRUCTURE IMPROVEMENT PROGRAM... measure used to track the qualifying hospital's progress in meeting its plan goals. (b) Review of annual...
Physics Division annual progress report for period ending December 31, 1975. [ORNL
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1976-05-01
Separate abstracts were prepared for each of the data-containing sections of this report. Additional sections deal with publications, titles of papers presented at scientific and technical meetings, personnel, etc. (RWR)
Abudho, Bernard O.; Ndombi, Eric M.; Guya, Bernard; Carter, Jennifer M.; Riner, Diana K.; Kittur, Nupur; Karanja, Diana M. S.; Secor, W. Evan; Colley, Daniel G.
2018-01-01
Abstract. Schistosomiasis remains a major public health problem in Kenya. The World Health Organization recommends preventive chemotherapy with praziquantel (PZQ) to control morbidity due to schistosomiasis. Morbidity is considered linked to intensity of infection, which along with prevalence is used to determine the frequency of mass drug administration (MDA) to school-age children. We determined the impact of annual school-based MDA on children across all primary and high school years using a repeated cross-sectional study design in five schools near Lake Victoria in western Kenya, an area endemic for Schistosoma mansoni. At baseline and for the following four consecutive years, between 897 and 1,440 school children in Grades 1–12 were enrolled and evaluated by Kato-Katz for S. mansoni and soil-transmitted helminths (STH), followed by annual MDA with PZQ and albendazole. Four annual rounds of MDA with PZQ were associated with reduced S. mansoni prevalence in all school children (44.7–14.0%; P < 0.001) and mean intensity of infection by 91% (90.4 to 8.1 eggs per gram [epg] of stool; P < 0.001). Prevalence of high-intensity infection (≥ 400 epg) decreased from 6.8% at baseline to 0.3% by the end of the study. Soil-transmitted helminth infections, already low at baseline, also decreased significantly over the years. In this high prevalence area, annual school-based MDA with high coverage across all Grades (1–12) resulted in rapid and progressive declines in overall prevalence and intensity of infection. This decrease was dramatic in regard to heavy infections in older school-attending children. PMID:29532768
Abudho, Bernard O; Ndombi, Eric M; Guya, Bernard; Carter, Jennifer M; Riner, Diana K; Kittur, Nupur; Karanja, Diana M S; Secor, W Evan; Colley, Daniel G
2018-05-01
Schistosomiasis remains a major public health problem in Kenya. The World Health Organization recommends preventive chemotherapy with praziquantel (PZQ) to control morbidity due to schistosomiasis. Morbidity is considered linked to intensity of infection, which along with prevalence is used to determine the frequency of mass drug administration (MDA) to school-age children. We determined the impact of annual school-based MDA on children across all primary and high school years using a repeated cross-sectional study design in five schools near Lake Victoria in western Kenya, an area endemic for Schistosoma mansoni . At baseline and for the following four consecutive years, between 897 and 1,440 school children in Grades 1-12 were enrolled and evaluated by Kato-Katz for S. mansoni and soil-transmitted helminths (STH), followed by annual MDA with PZQ and albendazole. Four annual rounds of MDA with PZQ were associated with reduced S. mansoni prevalence in all school children (44.7-14.0%; P < 0.001) and mean intensity of infection by 91% (90.4 to 8.1 eggs per gram [epg] of stool; P < 0.001). Prevalence of high-intensity infection (≥ 400 epg) decreased from 6.8% at baseline to 0.3% by the end of the study. Soil-transmitted helminth infections, already low at baseline, also decreased significantly over the years. In this high prevalence area, annual school-based MDA with high coverage across all Grades (1-12) resulted in rapid and progressive declines in overall prevalence and intensity of infection. This decrease was dramatic in regard to heavy infections in older school-attending children.
Challenges of Zinc-Specific Transrectal Fluorescence Tomography to Detect Prostate Cancer
2012-10-01
wavelength, aem and sem as those at emission wavelength, afl as the absorption coefficient of the fluorophore at the excitation wavelength, as the...tentatively accepted” by Medical Physics at the time of this annual report being submitted. The current pre-doctoral trainee PI is Mr. Anqi Zhang. The...year 2 report thus contains progresses contributed by both the former and current trainee PIs. During the year 2 of this study, we have furthered
Plasma Theory and Simulation Group Annual Progress Report for 1991
1991-12-31
beam formation analitically : i) the resistance of the (low-density) to the final, high-density cylindrical wall can be approximated by the regime...model is developed that predicts the ion angular distribution function in a highly collisional sheath. In a previous study2, the normal ion velocity...gets a linear dispersion relation of the form W2 = k 2 (T + Ti/m. + m,), (40) which predicts ion acoustic waves. These waves have the highest frequency
Department of Clinical Investigation Annual Research Progress Report, Fiscal Year 1984. Volume 2,
1984-10-01
Brooke Army Medical Center Dept/Svc Associate Investigators: Department of Pediatrics Key Words: Ewing ’s sarcoma Accumulative MEDCASE Eat Accumulative...Modality Therapy for Disseminated Soft Tissue 289 Sarcomas , Phase III. (0) SWOG 8025 Combination Chemotherapy for Chronic Lymphocytic Leukemia. 290 *(C...Metastatic Islet Cell 318 Carcinoma, Phase I1. (0) SWOG 8209 A Study of AZQ in Soft Tissue and Bony Sarcomas , Phase 1I. 319 (C) SWOG 8210 A Comparison
Department of Clinical Investigation Annual Research Progress Report, Fiscal Year 1985. Volume 2,
1985-10-01
Objective(s): To study the feasibility of cytosine arabinoside (ara-C), used in high dosage in conjunction with fractionated total body irradiation... Using High Dose Ara-C 335 in Adult Acute Leukemia and Chronic Granulocytic Leukemia in Blastic Crisis, Phase III. (0) SWOG 8328 Evaluation of...Fludarabine Phosphate in Cervical Cancer, 336 Phase II. (0) SWOG 8360 Use of the Surgically Implanted "Infusaid" Pump for Ambula- 337 tory Ottpatient Hepatic
1978-10-01
pulmonary ventilation via the " central chemoreceptors" (6.8) and to regulate cerebral blood flow (8,12). The " central chemoreceptors" for respiration are...decreases in illumination. Progress: The Hidden Shapes Test (I), the Maudsley Personality Inventory (2) and a personal history questionnaire were...hypoglycemia has been encountered occasionally in heatstroke but its pathogenesis is still uncertain. The contribution of central glucopenia to heatstroke coma
Lee, Soo Eon; Jahng, Tae-Ahn; Kim, Ki-Jeong; Hyun, Seung-Jae; Kim, Hyun Jib; Kawaguchi, Yoshiharu
2017-02-01
There has been a marked increase in spine surgery in the 21st century, but there are no reports providing quantitative and qualitative analyses of research by Korean spine surgeons. The study goal was to assess the status of Korean spinal surgery and research. The number of spine surgeries was obtained from the Korean National Health Insurance Service. Research articles published by Korean spine surgeons were reviewed by using the Medline/PubMed online database. The number of spine surgeries in Korea increased markedly from 92,390 in 2004 to 164,291 in 2013. During the 2000-2014 period, 1982 articles were published by Korean spine surgeons. The annual number of articles increased from 20 articles in 2000 to 293 articles in 2014. There was a positive correlation between the annual spine surgery and article numbers (p<0.001). There were 1176 original studies published, and there was an annual increase in articles with Oxford levels of evidence 1, 2, and 3. The mean five-year impact factor (IF) for article quality was 1.79. There was no positive correlation between the annual IF and article numbers. Most articles (65.9%) were authored by neurosurgical spine surgeons. But spinal deformity-related topics were dominant among articles authored by orthopedics. The results show a clear quantitative increase in Korean spinal surgery and research over the last 15years. The lack of a correlation between annual IF and published article numbers indicate that Korean spine surgeons should endeavor to increase research value. Copyright © 2016 Elsevier Ltd. All rights reserved.
ERIC Educational Resources Information Center
Department of Education, Washington, DC.
This 22nd annual report to Congress on the implementation of the Individuals with Disabilities Education Act 1997 (IDEA) begins with a special preface reflecting on the progress made in the 25 years since the initial passage of the law. Following the preface, Section 1 examines contextual and environmental factors such as the role of minority…
Annual research briefs, 1993. [Center for Turbulence Research
NASA Technical Reports Server (NTRS)
1993-01-01
The 1993 annual progress reports of the Research Fellow and students of the Center for Turbulence Research are included. The first group of reports are directed towards the theory and application of active control in turbulent flows including the development of a systematic mathematical procedure based on the Navier Stokes equations for flow control. The second group of reports are concerned with the prediction of turbulent flows. The remaining articles are devoted to turbulent reacting flows, turbulence physics, experiments, and simulations.
ERIC Educational Resources Information Center
Marlowe, Edward; And Others
This is the fourth report in a series which describes the results and progress in a long-term program to develop a Data Management System (DMS) and a Student Management System (SMS) for use in the Naval Student Pilot Training System. The DMS will contain all of the student naval aviator's data files needed to support an improved student training…
Hippe, Daniel S; Phan, Binh An P; Sun, Jie; Isquith, Daniel A; O'Brien, Kevin D; Crouse, John R; Anderson, Todd; Huston, John; Marcovina, Santica M; Hatsukami, Thomas S; Yuan, Chun; Zhao, Xue-Qiao
2018-03-01
To assess whether Lp(a) (lipoprotein(a)) levels and other lipid levels were predictive of progression of atherosclerosis burden as assessed by carotid magnetic resonance imaging in subjects who have been treated with LDL-C (low-density lipoprotein cholesterol)-lowering therapy and participated in the AIM-HIGH trial (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides: Impact on Global Health Outcomes). AIM-HIGH was a randomized, double-blind study of subjects with established vascular disease, elevated triglycerides, and low HDL-C (high-density lipoprotein cholesterol). One hundred fifty-two AIM-HIGH subjects underwent both baseline and 2-year follow-up carotid artery magnetic resonance imaging. Plaque burden was measured by the percent wall volume (%WV) of the carotid artery. Associations between annualized change in %WV with baseline and on-study (1 year) lipid variables were evaluated using multivariate linear regression and the Bonferroni correction to account for multiple comparisons. Average %WV at baseline was 41.6±6.8% and annualized change in %WV over 2 years ranged from -3.2% to 3.7% per year (mean: 0.2±1.1% per year; P =0.032). Increases in %WV were significantly associated with higher baseline Lp(a) (β=0.34 per 1-SD increase of Lp(a); 95% confidence interval, 0.15-0.52; P <0.001) after adjusting for clinical risk factors and other lipid levels. On-study Lp(a) had a similar positive association with %WV progression (β=0.33; 95% confidence interval, 0.15-0.52; P <0.001). Despite intensive lipid therapy, aimed at aggressively lowering LDL-C to <70 mg/dL, carotid atherosclerosis continued to progress as assessed by carotid magnetic resonance imaging and that elevated Lp(a) levels were independent predictors of increases in atherosclerosis burden. © 2018 American Heart Association, Inc.
Fuel Cell Buses in U.S. Transit Fleets: Current Status 2015
DOE Office of Scientific and Technical Information (OSTI.GOV)
Eudy, Leslie; Post, Matthew; Gikakis, Christina
This report, published annually, summarizes the progress of fuel cell electric bus (FCEB) development in the United States and discusses the achievements and challenges of introducing fuel cell propulsion in transit. Various stakeholders, including FCEB developers, transit agencies, and system integrators, have expressed the value of this annual status report, which provides a summary of results from evaluations performed by the National Renewable Energy Laboratory. The annual status report tracks the progress of the FCEB industry toward meeting technical targets, documents the lessons learned, and discusses the path forward for commercial viability of fuel cell technology for transit buses. Themore » 2015 summary results primarily focus on the most recent year for each demonstration, from August 2014 through July 2015. The results for these buses account for more than 1,045,000 miles traveled and 83,000 hours of fuel cell power system operation. The primary results presented in the report are from two demonstrations of fuel-cell-dominant bus designs: the Zero Emission Bay Area Demonstration Group led by Alameda-Contra Costa Transit District (AC Transit) in California and the American Fuel Cell Bus Project at SunLine Transit Agency in California.« less
Progress against cancer in the Netherlands since the late 1980s: an epidemiological evaluation.
Karim-Kos, Henrike E; Kiemeney, Lambertus A L M; Louwman, Marieke W J; Coebergh, Jan Willem W; de Vries, Esther
2012-06-15
Progress against cancer through prevention and treatment is often measured by survival statistics only instead of analyzing trends in incidence, survival and mortality simultaneously because of interactive influences. This study combines these parameters of major cancers to provide an overview of the progress achieved in the Netherlands since 1989 and to establish in which areas action is needed. The population-based Netherlands Cancer Registry and Statistics Netherlands provided incidence, 5-year relative survival and mortality of 23 major cancer types. Incidence, survival and mortality changes were calculated as the estimated annual percentage change. Optimal progress was defined as decreasing incidence and/or improving survival accompanied by declining mortality, and deterioration as increasing incidence and/or deteriorating survival accompanied by increasing mortality rates. Optimal progress was observed in 12 of 19 cancer types among males: laryngeal, lung, stomach, gallbladder, colon, rectal, bladder, prostate and thyroid cancer, leukemia, Hodgkin and non-Hodgkin lymphoma. Among females, optimal progress was observed in 12 of 21 cancers: stomach, gallbladder, colon, rectal, breast, cervical, uterus, ovarian and thyroid cancer, leukemia, Hodgkin and non-Hodgkin lymphoma. Deterioration occurred in three cancer types among males: skin melanoma, esophageal and kidney cancer, and among females six cancer types: skin melanoma, oral cavity, pharyngeal, esophageal, pancreatic and lung cancer. Our conceptual framework limits misinterpretations from separate trends and generates a more balanced discussion on progress. Copyright © 2011 UICC.
Real-world costs of autosomal dominant polycystic kidney disease in the Nordics.
Eriksson, Daniel; Karlsson, Linda; Eklund, Oskar; Dieperink, Hans; Honkanen, Eero; Melin, Jan; Selvig, Kristian; Lundberg, Johan
2017-08-15
There is limited real-world data on the economic burden of patients with autosomal dominant polycystic kidney disease (ADPKD). The objective of this study was to estimate the annual direct and indirect costs of patients with ADPKD by severity of the disease: chronic kidney disease (CKD) stages 1-3; CKD stages 4-5; transplant recipients; and maintenance dialysis patients. A retrospective study of ADPKD patients was undertaken April-December 2014 in Denmark, Finland, Norway and Sweden. Data on medical resource utilisation were extracted from medical charts and patients were asked to complete a self-administered questionnaire. A total of 266 patients were contacted, 243 (91%) of whom provided consent to participate in the study. Results showed that the economic burden of ADPKD was substantial at all levels of the disease. Lost wages due to reduced productivity were large in absolute terms across all disease strata. Mean total annual costs were highest in dialysis patients, driven by maintenance dialysis care, while the use of immunosuppressants was the main cost component for transplant care. Costs were twice as high in patients with CKD stages 4-5 compared to CKD stages 1-3. Costs associated with ADPKD are significant and the progression of the disease is associated with an increased frequency and intensity of medical resource utilisation. Interventions that can slow the progression of the disease have the potential to lead to substantial reductions in costs for the treatment of ADPKD.
Rebeiro, Peter F; Cesar, Carina; Shepherd, Bryan E; De Boni, Raquel B; Cortés, Claudia P; Rodriguez, Fernanda; Belaunzarán-Zamudio, Pablo; Pape, Jean W; Padgett, Denis; Hoces, Daniel; McGowan, Catherine C; Cahn, Pedro
2016-01-01
Introduction We assessed trends in HIV Care Continuum outcomes associated with delayed disease progression and reduced transmission within a large Latin American cohort over a decade: clinical retention, combination antiretroviral therapy (cART) use and viral suppression (VS). Methods Adults from Caribbean, Central and South America network for HIV epidemiology clinical cohorts in seven countries contributed data between 2003 and 2012. Retention was defined as two or more HIV care visits annually, >90 days apart. cART was defined as prescription of three or more antiretroviral agents annually. VS was defined as HIV-1 RNA <200 copies/mL at last measurement annually. cART and VS denominators were subjects with at least one visit annually. Multivariable modified Poisson regression was used to assess temporal trends and examine associations between age, sex, HIV transmission mode, cohort, calendar year and time in care. Results Among 18,799 individuals in retention analyses, 14,380 in cART analyses and 13,330 in VS analyses, differences existed between those meeting indicator definitions versus those not by most characteristics. Retention, cART and VS significantly improved from 2003 to 2012 (63 to 77%, 74 to 91% and 53 to 82%, respectively; p<0.05, each). Female sex (risk ratio (RR)=0.97 vs. males) and injection drug use as HIV transmission mode (RR=0.83 vs. male sexual contact with males (MSM)) were significantly associated with lower retention, but unrelated with cART or VS. MSM (RR=0.96) significantly decreased the probability of cART compared with heterosexual transmission. Conclusions HIV Care Continuum outcomes improved over time in Latin America, though disparities for vulnerable groups remain. Efforts must be made to increase retention, cART and VS, while engaging in additional research to sustain progress in these settings. PMID:27065108
Midwest Transportation Consortium annual progress report : October 2000.
DOT National Transportation Integrated Search
2000-10-01
From the Director: The Midwest Transportation Consortium (MTC), the University Transportation Center serving the states : of Iowa, Kansas, Missouri, and Nebraska, had a very successful first year of operation. The MTC is a : complex partnership invol...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Stiegler, J.O.
1986-06-01
The report is divided into the following: structural characterization, high-temperature alloy research, structural ceramics, radiation effects, structure and properties of surfaces and interfaces, and collaborative research centers. (DLC)
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-20
... implementing personalized learning environments, including narrative sections on progress and key performance... electronically through the Federal eRulemaking Portal at http://www.regulations.gov by selecting Docket ID number...
DOE Office of Scientific and Technical Information (OSTI.GOV)
NONE
2000-10-02
Scientific progress reports submitted by university researchers conducting projects funded through CPBR and metrics reports submitted by industry sponsors that provided matching funds to the projects.
United States Transuranium and Uranium Registries. Annual report February 1, 2001--January 31, 2002
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ehrhart, Susan M.; Filipy, Ronald E.
2002-07-01
This report documents the activities of the United States Transuranium and Uranium Registries (USTUR) from February 2001 through January 2002. Progress in continuing collaborations and several new collaborations is reviewed.
Zeiger, Sean; Hubbart, Jason A
2016-01-15
Suspended sediment (SS) remains the most pervasive water quality problem globally and yet, despite progress, SS process understanding remains relatively poor in watersheds with mixed-land-use practices. The main objective of the current work was to investigate relationships between suspended sediment and land use types at multiple spatial scales (n=5) using four years of suspended sediment data collected in a representative urbanized mixed-land-use (forest, agriculture, urban) watershed. Water samples were analyzed for SS using a nested-scale experimental watershed study design (n=836 samples×5 gauging sites). Kruskal-Wallis and Dunn's post-hoc multiple comparison tests were used to test for significant differences (CI=95%, p<0.05) in SS levels between gauging sites. Climate extremes (high precipitation/drought) were observed during the study period. Annual maximum SS concentrations exceeded 2387.6 mg/L. Median SS concentrations decreased by 60% from the agricultural headwaters to the rural/urban interface, and increased by 98% as urban land use increased. Multiple linear regression analysis results showed significant relationships between SS, annual total precipitation (positive correlate), forested land use (negative correlate), agricultural land use (negative correlate), and urban land use (negative correlate). Estimated annual SS yields ranged from 16.1 to 313.0 t km(-2) year(-1) mainly due to differences in annual total precipitation. Results highlight the need for additional studies, and point to the need for improved best management practices designed to reduce anthropogenic SS loading in mixed-land-use watersheds. Copyright © 2015 Elsevier B.V. All rights reserved.
Quality of Life and Outcomes in African Americans with CKD
Fischer, Michael J.; Wang, Xuelei; Brooks, Deborah; Bruce, Marino; Charleston, Jeanne; Cleveland, William H.; Dowie, Donna; Faulkner, Marquetta; Gassman, Jennifer; Hiremath, Leena; Kendrick, Cindy; Kusek, John W.; Norris, Keith C.; Thornley-Brown, Denyse; Greene, Tom; Lash, James P.
2014-01-01
Low health-related quality of life (HRQOL) has been associated with increased risk for hospitalization and death in ESRD. However, the relationship of HRQOL with outcomes in predialysis CKD is not well understood. We evaluated the association between HRQOL and renal and cardiovascular (CV) outcomes in 1091 African Americans with hypertensive CKD enrolled in the African American Study of Kidney Disease and Hypertension (AASK) trial and cohort studies. Outcomes included CKD progression (doubling of serum creatinine/ESRD), CV events/CV death, and a composite of CKD progression or death from any cause (CKD progression/death). We assessed HRQOL, including mental health composite (MHC) and physical health composite (PHC), using the Short Form-36 survey. Cox regression analyses were used to assess the relationship between outcomes and five-point decrements in MHC and PHC scores using measurements at baseline, at the most recent annual visit (time-varying), or averaged from baseline to the most recent visit (cumulative). During approximately 10 years of follow-up, lower mean PHC score was associated with increased risk of CV events/CV death and CKD progression/death across all analytic approaches, but only time-varying and cumulative decrements were associated with CKD progression. Similarly, lower mean MHC score was associated with increased risk of CV events/CV death regardless of analytic approach, while only time-varying and cumulative decrements in mean MHC score was associated with CKD progression and CKD progression or death. In conclusion, lower HRQOL is associated with a range of adverse outcomes in African Americans with hypertensive CKD. PMID:24700865
Quality of life and outcomes in African Americans with CKD.
Porter, Anna; Fischer, Michael J; Wang, Xuelei; Brooks, Deborah; Bruce, Marino; Charleston, Jeanne; Cleveland, William H; Dowie, Donna; Faulkner, Marquetta; Gassman, Jennifer; Hiremath, Leena; Kendrick, Cindy; Kusek, John W; Norris, Keith C; Thornley-Brown, Denyse; Greene, Tom; Lash, James P
2014-08-01
Low health-related quality of life (HRQOL) has been associated with increased risk for hospitalization and death in ESRD. However, the relationship of HRQOL with outcomes in predialysis CKD is not well understood. We evaluated the association between HRQOL and renal and cardiovascular (CV) outcomes in 1091 African Americans with hypertensive CKD enrolled in the African American Study of Kidney Disease and Hypertension (AASK) trial and cohort studies. Outcomes included CKD progression (doubling of serum creatinine/ESRD), CV events/CV death, and a composite of CKD progression or death from any cause (CKD progression/death). We assessed HRQOL, including mental health composite (MHC) and physical health composite (PHC), using the Short Form-36 survey. Cox regression analyses were used to assess the relationship between outcomes and five-point decrements in MHC and PHC scores using measurements at baseline, at the most recent annual visit (time-varying), or averaged from baseline to the most recent visit (cumulative). During approximately 10 years of follow-up, lower mean PHC score was associated with increased risk of CV events/CV death and CKD progression/death across all analytic approaches, but only time-varying and cumulative decrements were associated with CKD progression. Similarly, lower mean MHC score was associated with increased risk of CV events/CV death regardless of analytic approach, while only time-varying and cumulative decrements in mean MHC score was associated with CKD progression and CKD progression or death. In conclusion, lower HRQOL is associated with a range of adverse outcomes in African Americans with hypertensive CKD. Copyright © 2014 by the American Society of Nephrology.
International VLBI Service for Geodesy and Astrometry 2000 Annual Report
NASA Technical Reports Server (NTRS)
Vandenberg, N. R. (Editor); Baver, K. D. (Editor); Smith, David E. (Technical Monitor)
2000-01-01
This volume of reports is the 2000 Annual Report of the International Very Long Base Interferometry (VLBI) Service for Geodesy and Astrometry (IVS). The individual reports were contributed by VLBI groups in the international geodetic and astrometric community who constitute the permanent components of IVS. The IVS 2000 Annual Report documents the work of the IVS components for the period March 1, 1999 (the official inauguration date of IVS) through December 31, 2000. The reports document changes, activities, and progress of the IVS. The entire contents of this Annual Report also appear on the IVS web site at http://ivscc.gsfc.nasa.gov/publications/ar2000. This book and the web site are organized as follows: (1) The first section contains general information about IVS, a map showing the location of the components, information about the Directing Board members, and the report of the IVS Chair; (2) The second section of Special Reports contains a status report of the IVS Working Group on GPS phase center mapping, a reproduction of the resolution making IVS a Service of the International Astronomical Union (IAU), and a reprint of the VLBI Standard Interface (VSI); (3) The next seven sections hold the component reports from the Coordinators, Network Stations, Operation Centers, Correlators, Data Centers, Analysis Centers, and Technology Development Centers; and (4) The last section includes reference information about IVS: the Terms of Reference, the lists of Member and Affiliated organizations, the IVS Associate Member list, a complete list of IVS components, the list of institutions contributing to this report, and a list of acronyms. The 2000 Annual Report demonstrates the vitality of the IVS and the outstanding progress we have made during our first 22 months.
Relationship Between Proximal Aorta Morphology and Progression Rate of Aortic Stenosis.
Capoulade, Romain; Teoh, Jonathan G; Bartko, Philipp E; Teo, Eliza; Scholtz, Jan-Erik; Tastet, Lionel; Shen, Mylene; Mihos, Christos G; Park, Yong H; Garcia, Julio; Larose, Eric; Isselbacher, Eric M; Sundt, Thoralf M; MacGillivray, Thomas E; Melnitchouk, Serguei; Ghoshhajra, Brian B; Pibarot, Philippe; Hung, Judy
2018-05-01
The aim of this study was to examine the association between abnormal morphology of the proximal aorta and aortic stenosis (AS) progression rate. The main hypothesis was that morphologic changes of the proximal aorta, such as effacement of the sinotubular junction (STJ), result in increased biomechanical stresses and contribute to calcification and progression of AS. Between 2010 and 2012, 426 patients with mild to moderate AS were included in this study. Proximal aortic dimensions were measured at three different levels (i.e., sinus of Valsalva, STJ, and ascending aorta), and sinuses of Valsalva/STJ and ascending aorta/STJ ratios were used to determine degree of aortic deformity. AS progression rate was assessed by annualized increase in mean gradient (median follow-up time, 3.1 years; interquartile range, 2.6-3.9 years). The degree of aortic flow turbulence was examined in 18 matched patients with and without STJ effacement using cardiac magnetic resonance phase-contrast imaging. Patients' mean age was 71 ± 13 years, and 64% were men. Patients with low ratios had greater AS progression (P < .05). After comprehensive adjustment, sinuses of Valsalva/STJ (P = .025) and ascending aorta/STJ (P = .027) ratios were independently associated with greater AS progression rate. Compared with patients without STJ effacement, those with effacement of the STJ had higher degrees of aortic flow turbulence (24.4% vs 17.2%, P = .038). Effacement of the STJ is independently associated with greater AS progression, regardless of arterial hemodynamics, aortic valve phenotype, or baseline AS severity. Patients with abnormal proximal aortic geometry had disturbed aortic flow patterns. These findings suggest an interrelation between proximal aorta morphology and stenosis progression. Copyright © 2017 American Society of Echocardiography. Published by Elsevier Inc. All rights reserved.
Amoakwa, Kojo; Fashanu, Oluwaseun E; Tibuakuu, Martin; Zhao, Di; Guallar, Eliseo; Whelton, Seamus P; O'Neal, Wesley T; Post, Wendy S; Budoff, Matthew J; Michos, Erin D
2018-06-01
Left-sided valvular calcification is associated with cardiovascular disease (CVD) morbidity and mortality. Resting heart rate (RHR) may influence valvular calcium progression through shear stress. Whether RHR, an established CVD risk factor, is associated with valvular calcium progression is unknown. We assessed whether RHR predicts incidence and progression of mitral annular calcium (MAC) and aortic valve calcium (AVC) in a community-based cohort free of CVD at baseline. RHR was obtained from baseline electrocardiograms of 5498 MESA participants. MAC and AVC were quantified using Agatston scoring from cardiac computed tomography scans obtained at baseline and at a second examination during follow-up. We examined associations of RHR with incident MAC/AVC and annual change in MAC/AVC scores, after adjusting for demographics, CVD risk factors, physical activity, and atrioventricular nodal blocker use. At baseline, participants had mean age of 62 ± 10 years and mean RHR of 63 ± 10 bpm; 12.3% and 8.9% had prevalent AVC and MAC, respectively. Over a median of 2.3 years, 4.1% and 4.5% developed incident AVC and MAC, respectively. Each 10 bpm higher RHR was significantly associated with incident MAC [Risk Ratio 1.17 (95% CI 1.03-1.34)], but not incident AVC. However, RHR was associated with AVC progression [β = 1.62 (0.45-2.80) Agatston units/year for every 10 bpm increment], but not MAC progression. Higher RHR was associated with MAC incidence and AVC progression, independent of traditional CVD risk factors. Future studies are needed to determine whether modification of RHR through lifestyle or pharmacologic interventions can reduce valvular calcium incidence or progression. Copyright © 2018 Elsevier B.V. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Taylor, P.W.
1996-04-01
In the initial year of the grant, we have made excellent progress in several arenas: (1) A crystal structure of a mouse acetylcholinesterase-fasciculin 2 complex has been solved. (2) Studies with enantiomeric organophosphates have yielded vital information on their binding orientation in the ground and transition states. (3) Studies in oxime reactivation of inhibited cholinesterase have uncovered the basis for enhanced reactivity of HI-6 compared to 2-PAM. (4) The interactions of fasciculin 2 with acetylcholinesterase have been studied by kinetic and site-specific mutagenesis methods.
Environmental Hazards Assessment Program annual report, [June 1992--June 1993
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1993-10-01
This report, the Environment Hazards Assessment Program (EHAP) Annual Report, is the second of three reports that document activities under the EHAP grant and details progress made during the first year of the grant. The first year was devoted to the development of a working program implementation plan. During the developmental process some key objectives were achieved such as developing a Doctor of Philosophy degree program in Environmental Studies at MUSC (Medical University of South Carolina) and conducting the first Crossroads of Humanity series Round Table Forum. The PIP (Program Implementation Program) details the objectives, management and budgetary basis formore » the overall management and control of the grant over the next four years, the yearly program plans provide the monthly and day-to-day programmatic and budgetary control by which the PIP was developed.« less
FY 2005 Annual Progress Report for the DOE Hydrogen Program
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
In cooperation with industry, academia, national laboratories, and other government agencies, the Department of Energy's Hydrogen Program is advancing the state of hydrogen and fuel cell technologies in support of the President's Hydrogen Fuel Initiative. The initiative seeks to develop hydrogen, fuel cell, and infrastructure technologies needed to make it practical and cost-effective for Americans to choose to use fuel cell vehicles by 2020. Significant progress was made in fiscal year 2005 toward that goal.
NASA Technical Reports Server (NTRS)
Mikic, Zoran
2003-01-01
This report covers technical progress during the first six months of the first year of NASA SR&T contract "Modeling the Magnetic and Thermal Structure of Active Regions", NASW-03008, between NASA and Science Applications International Corporation, and covers the period January 14, 2003 to July 13, 2003. Under this contract SAIC has conducted research into theoretical modeling of the properties of active regions using the MHD model.
NASA Technical Reports Server (NTRS)
Envia, Edmane; Thomas, Russell
2007-01-01
As part of the Fundamental Aeronautics Program Annual Review, a summary of the progress made in 2007 in acoustics research under the Subsonic Fixed Wing project is given. The presentation describes highlights from in-house and external activities including partnerships and NRA-funded research with industry and academia. Brief progress reports from all acoustics Phase 1 NRAs are also included as are outlines of the planned activities for 2008 and all Phase 2 NRAs. N+1 and N+2 technology paths outlined for Subsonic Fixed Wing noise targets. NRA Round 1 progressing with focus on prediction method advancement. NRA Round 2 initiating work focused on N+2 technology, prediction methods, and validation. Excellent partnerships in progress supporting N+1 technology targets and providing key data sets.
Boucquemont, Julie; Metzger, Marie; Combe, Christian; Stengel, Bénédicte; Leffondre, Karen
2014-01-01
In studies investigating risk factors of chronic kidney disease (CKD) progression, one may be interested in estimating factors effects on both a fall of glomerular filtration rate (GFR) below a specific level (i.e., a CKD stage) and death. Such studies have to account for the fact that GFR is measured at intermittent visit only, which implies that progression to the stage of interest is unknown for patients who die before being observed at that stage. Our objective was to compare the results of an illness-death model that handles this uncertainty, with frequently used survival models. This study included 1,519 patients from the NephroTest cohort with CKD stages 1-4 at baseline (69% males, 59±15 years, median protein/creatinine ratio [PCR] 27.4 mg/mmol) and subsequent annual measures of GFR (follow-up time 4.3±2.7 years). Each model was used to estimate the effects of sex, age, PCR, and GFR at baseline on the hazards of progression to CKD stage 5 (GFR<15 mL/min/1.73 m2, n = 282 observed) and death (n = 168). For progression to stage 5, there were only minor differences between results from the different models. The differences between results were higher for the hazard of death before or after progression. Our results also suggest that previous findings on the effect of age on end-stage renal disease are more likely due to a strong impact of age on death than to an effect on progression. The probabilities of progression were systematically under-estimated with the survival model as compared with the illness-death model. This study illustrates the advantages of the illness-death model for accurately estimating the effects of risk factors on the hazard of progression and death, and probabilities of progression. It avoids the need to choose arbitrary time-to-event and time-to-censoring, while accounting for both interval censoring and competition by death, using a single analytical model.
Midwest Transportation Consortium annual progress report : October 2002.
DOT National Transportation Integrated Search
2002-10-01
From the Director: For the past three years, the Midwest Transportation Consortium (MTC) has focused its efforts in : supporting the development and use of asset management systems in transportation. The MTCs main : focus is on human capital devel...
29 CFR 1960.71 - Agency annual reports.
Code of Federal Regulations, 2010 CFR
2010-07-01
... individual agency progress and problems in correcting unsafe or unhealthful working conditions, and... Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) BASIC PROGRAM ELEMENTS FOR FEDERAL EMPLOYEE OCCUPATIONAL SAFETY AND HEALTH PROGRAMS AND RELATED...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Satyapal, Sunita
The 2011 Annual Progress Report summarizes fiscal year 2011 activities and accomplishments by projects funded by the DOE Hydrogen Program. It covers the program areas of hydrogen production and delivery; hydrogen storage; fuel cells; manufacturing; technology validation; safety, codes and standards; education; market transformation; and systems analysis.
UAS Integration in the NAS FY15 Annual Review
NASA Technical Reports Server (NTRS)
Grindle, Laurie; Randall, Debra; Hackenburg, Davis
2015-01-01
This presentation gives insight into the research activities and efforts being executed in order to integrate unmanned aircraft systems into the national airspace system. This briefing is to inform others of the UAS-NAS progress and future directions.
Fuel Cell Buses in U.S. Transit Fleets : Current Status 2014
DOT National Transportation Integrated Search
2014-12-03
This report, published annually, summarizes the progress of fuel cell electric bus (FCEB) development in the United States and discusses the achievements and challenges of introducing fuel cell propulsion in transit. Various stakeholders, including d...
DOE Office of Scientific and Technical Information (OSTI.GOV)
none,
The 2013 Annual Progress Report summarizes fiscal year 2013 activities and accomplishments by projects funded by the DOE Hydrogen Program. It covers the program areas of hydrogen production and delivery; hydrogen storage; fuel cells; manufacturing; technology validation; safety, codes and standards; market transformation; and systems analysis.
Pharmacogenetics in Acute Lymphoblastic Leukemia
Cheok, Meyling H.; Pottier, Nicolas; Kager, Leo
2009-01-01
Progress in the treatment of acute leukemia in children has been remarkable, from a disease being lethal four decades ago to current cure rates exceeding 80%. This exemplary progress is largely due to the optimization of existing treatment modalities rather than the discovery of new antileukemic agents. However, despite these high cure rates, the annual number of children whose leukemia relapses after their initial therapy remains greater than that of new cases of most types of childhood cancers. The aim of pharmacogenetics is to develop strategies to personalize treatment and tailor therapy to individual patients, with the goal of optimizing efficacy and safety through better understanding of human genome variability and its influence on drug response. In this review, we summarize recent pharmacogenomic studies related to the treatment of pediatric acute lymphoblastic leukemia. These studies illustrate the promise of pharmacogenomics to further advance the treatment of human cancers, with childhood leukemia serving as a paradigm. PMID:19100367
Annual Research Progress Report. Fiscal Year 1989. Volume 1
1989-10-01
Wounds and 49 the Incidence of Wound Infections Associated with These Injuries . (T) C-67-86 The Choice of Antibiotics for Marine Acquired Wound...Spinal 239 Injury . (C) (PR) C-38-88 Bone Density Changes with Compression Plating of Fractures. (0) 240 (PR) C-39-88 Evaluation of Constituents in the...Biomechanical 279 Study Using Cadaver Model. (0) C-37-89 Evaluation of Stroke Mechanics to Shoulder Pain in the Swimmer. 280 (C) C-48-89 Extended Follow-up of
What's changed and what's stayed the same: a case study in nursing and philanthropy.
Judge, Kate
2014-01-01
Philanthropic resources can help the nursing profession and nurses advance the health of the nation. While progress has been made by nursing organizations, primarily in academia, to fundraise for nursing-focused projects over the last 20 years, nursing receives little of the total annual US giving. The American Nurses Foundation's recent expansion provides an example of changes in philanthropy within the context of how the core principles of fundraising and market change can leverage giving for nursing activities and nurses.
Walter Reed Army Medical Center, Washington, DC Annual Progress Report FY-89. Volume 2. Part 1
1990-01-02
recurrent head and neck cancer who meet the eligibility requirements and consent to the protocol will have central venous catheter placed (if one is...DATE: 06/29/89 WORK UNIT # 6220 DETAIL SUMMARY SHEET TITLE: Epidemiology of HIV In Pediatric and Perinatal Patients - A Natural History Study...of HIV in clinical samples. 16 I I REPORT DATE: 04/04/89 WORK UNIT # 8804 DETAIL SUMMARY SHEET TITLE: The Natural History of HIV Infection and Disease
DOE Office of Scientific and Technical Information (OSTI.GOV)
Spotila, J.R.; Standora, E.A.
1982-08-01
Field experiments are underway to determine the behavioral mechanisms by which largemouth bass, Micropterus salmoides, respond to rapid temperature changes in their natural environment. Site specificity of largemouth bass in Pond C has been determined. Laboratory experiments are clarifying the relationship between basking behavior of the turtle, Pseudemys scripta and its nutritional state. Theoretical analysis and mathematical modeling continue and have been used to define the role of body size in the thermoregulation of turtles.
1979-10-01
J. B. Sampson. A new inventory for the assessment of symptom occurrence and severity at high altitude. Aviat. Space Environ. Med. 50(9)925:929, 1979...Aviat. Space Environ. Med. 47:280-301, 1976. 3. Caridis, D. T., R. B. Reinhold, P. W. Woodruff and J. Fine. Endotoxemia in man. Lancet. 2:1381-1386...Accidental hypothermia: An experimental study of practical rewarming methods. Aviat. Space Environ. Med. 48:625-632, 1977. 4. D’Amato, H. E., S. Kronhein
Shields, Judith A; Jennings, Jerry L
2013-01-01
A national healthcare company applied the Malcolm Baldrige Criteria for Performance Excellence and its "Are We Making Progress?" survey as an annual organizational self-assessment to identify areas for improvement. For 6 years, Liberty Healthcare Corporation reviewed the survey results on an annual basis to analyze positive and negative trends, monitor company progress toward targeted goals and develop new initiatives to address emerging areas for improvement. As such, the survey provided a simple and inexpensive methodology to gain useful information from employees at all levels and from multiple service sites and business sectors. In particular, it provided a valuable framework for assessing and improving the employees' commitment to the company's mission and values, high standards and ethics, quality of work, and customer satisfaction. The methodology also helped the company to incorporate the philosophy and principles of continuous quality improvement in a unified fashion. Corporate and local leadership used the same measure to evaluate the performance of individual programs relative to each other, to the company as a whole, and to the "best practices" standard of highly successful companies that received the Malcolm Baldrige National Quality Award. © 2012 National Association for Healthcare Quality.
Cleaner cooking solutions to achieve health, climate, and economic cobenefits.
Anenberg, Susan C; Balakrishnan, Kalpana; Jetter, James; Masera, Omar; Mehta, Sumi; Moss, Jacob; Ramanathan, Veerabhadran
2013-05-07
Nearly half the world's population must rely on solid fuels such as biomass (wood, charcoal, agricultural residues, and animal dung) and coal for household energy, burning them in inefficient open fires and stoves with inadequate ventilation. Household solid fuel combustion is associated with four million premature deaths annually; contributes to forest degradation, loss of habitat and biodiversity, and climate change; and hinders social and economic progress as women and children spend hours every day collecting fuel. Several recent studies, as well as key emerging national and international efforts, are making progress toward enabling wide-scale household adoption of cleaner and more efficient stoves and fuels. While significant challenges remain, these efforts offer considerable promise to save lives, improve forest sustainability, slow climate change, and empower women around the world.
Shaker, Saher B; Dirksen, Asger; Ulrik, Charlotte S; Hestad, Marianne; Stavngaard, Trine; Laursen, Lars C; Maltbaek, Niels; Clementsen, Paul; Skjaerbaek, Nanna; Nielsen, Lars; Stoel, Berend; Skovgaard, Lene T; Tonnesen, Philip
2009-04-01
The objective was to evaluate the effect of inhaled corticosteroids on disease progression in smokers with moderate to severe chronic obstructive pulmonary disease (COPD), as assessed by annual computed tomography (CT) using lung density (LD) measurements. Two hundred and fifty-four current smokers with COPD were randomised to treatment with either an inhaled corticosteroids (ICS), budesonide 400 microg bid, or placebo. COPD was defined as FEV(1) < or = 70% pred, FEV(1)/FVC < or = 60% and no reversibility to beta(2)-agonists and oral corticosteroids. The patients were followed for 2-4 years with biannual spirometry and annual CT and comprehensive lung function tests (LFT). CT images were analysed using Pulmo-CMS software. LD was derived from a pixel-density histogram of the whole lung as the 15th percentile density (PD15) and the relative area of emphysema at a threshold of -910 Hounsfield units (RA-910), and both were volume-adjusted to predicted total lung capacity. At baseline, mean age was 64 years and 64 years; mean number of pack-years was 56 and 56; mean FEV(1) was 1.53 L (51% pred) and 1.53 L (53% pred); mean PD15 was 103 g/L and 104 g/L; and mean RA-910 was 14% and 13%, respectively, for the budesonide and placebo groups. The annual fall in PD15 was -1.12 g/L in the budesonide group and -1.81 g/L in the placebo group (p = 0.09); the annual increase in RA-910 was 0.4% in the budesonide group and 1.1% in the placebo group (p = 0.02). There was no difference in annual decline in FEV(1) between ICS (-54 mL) and placebo (-56 mL) (p = 0.89). Long-term budesonide inhalation shows a non-significant trend towards reducing the progression of emphysema as determined by the CT-derived 15th percentile lung density from annual CT scans in current smokers with moderate to severe COPD.
Chen, Yanxian; Chang, Billy Heung Wing; Ding, Xiaohu; He, Mingguang
2016-01-01
In the present study we attempt to use hypothesis-independent analysis in investigating the patterns in refraction growth in Chinese children, and to explore the possible risk factors affecting the different components of progression, as defined by Principal Component Analysis (PCA). A total of 637 first-born twins in Guangzhou Twin Eye Study with 6-year annual visits (baseline age 7–15 years) were available in the analysis. Cluster 1 to 3 were classified after a partitioning clustering, representing stable, slow and fast progressing groups of refraction respectively. Baseline age and refraction, paternal refraction, maternal refraction and proportion of two myopic parents showed significant differences across the three groups. Three major components of progression were extracted using PCA: “Average refraction”, “Acceleration” and the combination of “Myopia stabilization” and “Late onset of refraction progress”. In regression models, younger children with more severe myopia were associated with larger “Acceleration”. The risk factors of “Acceleration” included change of height and weight, near work, and parental myopia, while female gender, change of height and weight were associated with “Stabilization”, and increased outdoor time was related to “Late onset of refraction progress”. We therefore concluded that genetic and environmental risk factors have different impacts on patterns of refraction progression. PMID:27874105
Genetic progress in sunflower crop in Rio Grande do Sul State, Brazil.
Follmann, D N; Cargnelutti Filho, A; Lorentz, L H; Boligon, A A; Caraffa, M; Wartha, C A
2017-04-13
The sunflower has adaptability to growing regions with different climatic and soil characteristics, showing drought tolerance and high-quality oil production. The State of Rio Grande do Sul is the third largest sunflower producer in Brazil, with research related to the sunflower breeding initiated after the decade of 1950. The aim of this study was to evaluate the genetic progress for grain yield, oil content, and oil yield of sunflower (Helianthus annuus L.) in the State of Rio Grande do Sul. Data of grain yield, oil content, and oil yield obtained from 58 sunflower cultivar yield trials in 19 municipalities in Rio Grande do Sul during the period from 2005 to 2014 were used. Genetic progress was studied according to the methodology proposed by Vencovsky and data from sunflower cultivar yield trials were used. Annual genetic progress of sunflower during the period of 10 years (2005-2014) was 132.46 kg⋅ha -1 ⋅year -1 for grain yield, -0.17%/year for oil content, and 48.11 kg⋅ha -1 ⋅year -1 for oil yield. The sunflower-breeding programs in the State of Rio Grande do Sul were efficient for the traits grain yield and oil yield and presented no efficiency for oil content.
Medeiros, Felipe A.; Alencar, Luciana M.; Zangwill, Linda M.; Bowd, Christopher; Vizzeri, Gianmarco; Sample, Pamela A.; Weinreb, Robert N.
2010-01-01
Purpose To evaluate the ability of scanning laser polarimetry with variable corneal compensation to detect progressive retinal nerve fiber layer (RNFL) loss in glaucoma patients and patients suspected of having the disease. Methods This was an observational cohort study that included 335 eyes of 195 patients. Images were obtained annually with the GDx VCC scanning laser polarimeter, along with optic disc stereophotographs and standard automated perimetry (SAP) visual fields. The median follow-up time was 3.94 years. Progression was determined using commercial software for SAP and by masked assessment of optic disc stereophotographs performed by expert graders. Random coefficient models were used to evaluate the relationship between RNFL thickness measurements over time and progression as determined by SAP and/or stereophotographs. Results From the 335 eyes, 34 (10%) showed progression over time by stereophotographs and/or SAP. Average GDx VCC measurements decreased significantly over time for both progressors as well as non-progressors. However, the rate of decline was significantly higher in the progressing group (−0.70 μm/year) compared to the non-progressing group (−0.14 μm/year; P = 0.001). Black race and male sex were significantly associated with higher rates of RNFL loss during follow-up. Conclusions The GDx VCC scanning laser polarimeter was able to identify longitudinal RNFL loss in eyes that showed progression in optic disc stereophotographs and/or visual fields. These findings suggest that this technology could be useful to detect and monitor progressive disease in patients with established diagnosis of glaucoma or suspected of having the disease. PMID:19029038
Driban, Jeffrey B.; Eaton, Charles B.; Lo, Grace H.; Ward, Robert J.; Lu, Bing; McAlindon, Timothy E.
2014-01-01
Objective We aimed to evaluate if a recent knee injury was associated with accelerated knee osteoarthritis (KOA) progression. Methods In the Osteoarthritis Initiative (OAI) we studied participants free of KOA on their baseline radiographs (Kellgren-Lawrence [KL]<2). We compared three groups: 1) individuals with accelerated progression of KOA: defined as having at least one knee that progressed to end-stage KOA (KL Grade 3 or 4) within 48 months, 2) common KOA progression: at least one knee increased in radiographic scoring within 48 months (excluding those defined as accelerated KOA), and 3) no KOA: no change in KL grade in either knee. At baseline, participants were asked if their knees had ever been injured and at each annual visit they were asked about injuries during the prior 12 months. We used multinomial logistic regressions to determine if a new knee injury was associated with the outcome of accelerated KOA or common KOA progression after adjusting for age, sex, body mass index, static knee malalignment, and systolic blood pressure. Results A knee injury during the total observation period was associated with accelerated KOA progression (n=54, odds ratio [OR]=3.14) but not common KOA progression (n=187, OR=1.08). Furthermore, a more recent knee injury (within a year of the outcome) was associated with accelerated (OR=8.46) and common KOA progression (OR=3.12). Conclusion Recent knee injuries are associated with accelerated KOA. Most concerning is that certain injuries may be associated with a rapid cascade towards joint failure in less than one year. PMID:24782446
Patterson, Marc C; Mengel, Eugen; Vanier, Marie T; Schwierin, Barbara; Muller, Audrey; Cornelisse, Peter; Pineda, Mercè
2015-05-28
Niemann-Pick disease type C (NP-C) is a rare neurovisceral disease characterised by progressive neurological degeneration, where the rate of neurological disease progression varies depending on age at neurological onset. We report longitudinal data on functional disease progression and safety observations in patients in the international NPC Registry who received continuous treatment with miglustat. The NPC Registry is a prospective observational cohort of NP-C patients. Enrolled patients who received ≥1 year of continuous miglustat therapy (for ≥90 % of the observation period, with no single treatment interruption >28 days) were included in this analysis. Disability was measured using a scale rating the four domains, ambulation, manipulation, language and swallowing from 0 (normal) to 1 (worst). Neurological disease progression was analysed in all patients based on: 1) annual progression rates between enrolment and last follow up, and; 2) categorical analysis with patients categorised as 'improved/stable' if ≥3/4 domain scores were lower/unchanged, and as 'progressed' if <3 scores were lower/unchanged between enrolment and last follow-up visit. In total, 283 patients were enrolled from 28 centers in 13 European countries, Canada and Australia between September 2009 and October 2013; 92 patients received continuous miglustat therapy. The mean (SD) miglustat exposure during the observation period (enrolment to last follow-up) was 2.0 (0.7) years. Among 84 evaluable patients, 9 (11 %) had early-infantile (<2 years), 27 (32 %) had late-infantile (2 to <6 years), 30 (36 %) had juvenile (6 to <15 years) and 18 (21 %) had adolescent/adult (≥15 years) onset of neurological manifestations. The mean (95%CI) composite disability score among all patients was 0.37 (0.32,0.42) at enrolment and 0.44 (0.38,0.50) at last follow-up visit, and the mean annual progression rate was 0.038 (0.018,0.059). Progression of composite disability scores appeared highest among patients with neurological onset during infancy or childhood and lowest in those with adolescent/adult-onset. Overall, 59/86 evaluable patients (69 %) were categorized as improved/stable and the proportion of improved/stable patients increased with age at neurological onset. Safety findings were consistent with previous data. Disability status was improved/stable in the majority of patients who received continuous miglustat therapy for an average period of 2 years.
2013 Geothermal Technologies Office Peer Review Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Geothermal Technologies Office
Geothermal Technologies Office conducted its annual program peer review in April of 2013. The review provided an independent, expert evaluation of the technical progress and merit of GTO-funded projects. Further, the review was a forum for feedback and recommendations on future GTO strategic planning. During the course of the peer review, DOE-funded projects were evaluated for 1) their contribution to the mission and goals of the GTO and 2) their progress against stated project objectives. Principal Investigators (PIs) came together in sessions organized by topic “tracks” to disseminate information, progress, and results to a panel of independent experts as wellmore » as attendees.« less
Pearson, Edward; McGarry, Lisa; Gala, Smeet; Nieset, Christopher; Nanavaty, Merena; Mwamburi, Mkaya; Levy, Yair
2016-04-01
Treatment of newly-diagnosed patients with chronic-phase chronic myeloid leukemia (CP-CML) with tyrosine kinase inhibitors (TKIs) results in near-normal life expectancy. However, CP-CML patients resistant to initial TKIs face a poorer prognosis and significantly higher CML-related mortality. We conducted a systematic literature review to evaluate the specific causes of deaths (diseases progression versus drug-related) in CP-CML patients receiving second- or third-line therapy. We identified eight studies based on our criteria that reported causes of death. Overall, 5% of second-line and 10% of third-line patients died during the study follow-up period. For second-line, (7 studies, n=1926), mortality was attributed to disease progression for 41% of deaths, 2% to treatment-related causes, 3% were treatment-unrelated, and 50% were unspecified adverse events (AEs), not likely related to study drug. In third-line, (2 studies, n=144), 71% deaths were attributed to disease progression, 7% treatment-related AEs, 14% treatment-unrelated and 7% unspecified AEs. Annual death rates for second- and third-line therapy were significantly higher than for general population in similar age group. Our findings suggest death attributed to disease progression is approximately 10 times that due to treatment-related AEs in patients with CP-CML receiving second- or third-line therapy. Therefore, the potential benefits of effective treatment for these patients with the currently available TKIs outweigh the risks of treatment-induced AEs. Copyright © 2016 Elsevier Ltd. All rights reserved.
Psychophysical Evaluation of Three-Dimensional Auditory Displays
NASA Technical Reports Server (NTRS)
Wightman, Frederic L.
1996-01-01
This report describes the progress made during the second year of a three-year Cooperative Research Agreement. The CRA proposed a program of applied psychophysical research designed to determine the requirements and limitations of three-dimensional (3-D) auditory display systems. These displays present synthesized stimuli to a pilot or virtual workstation operator that evoke auditory images at predetermined positions in space. The images can be either stationary or moving. In previous years, we completed a number of studies that provided data on listeners' abilities to localize stationary sound sources with 3-D displays. The current focus is on the use of 3-D displays in 'natural' listening conditions, which include listeners'head movements, moving sources, multiple sources and 'echoic' sources. The results of our research on one of these topics, the localization of multiple sources, was reported in the most recent Semi-Annual Progress Report (Appendix A). That same progress report described work on two related topics, the influence of a listener's a-priori knowledge of source characteristics and the discriminability of real and virtual sources. In the period since the last Progress Report we have conducted several new studies to evaluate the effectiveness of a new and simpler method for measuring the HRTF's that are used to synthesize virtual sources and have expanded our studies of multiple sources. The results of this research are described below.
Koya, D; Haneda, M; Inomata, S; Suzuki, Y; Suzuki, D; Makino, H; Shikata, K; Murakami, Y; Tomino, Y; Yamada, K; Araki, S I; Kashiwagi, A; Kikkawa, R
2009-10-01
There is currently insufficient evidence to recommend a low-protein diet for type 2 diabetic patients with diabetic nephropathy. We assessed whether a low-protein diet could prevent the progression of diabetic nephropathy. This was a multi-site parallel randomised controlled trial for prevention of diabetic nephropathy progression among 112 Japanese type 2 diabetic patients with overt nephropathy. It was conducted in Japan from 1 December 1997 to 30 April 2006. The participants were randomly assigned using a central computer-generated schedule to either low-protein diet (0.8 g kg(-1) day(-1)) and normal-protein diet (1.2 g kg(-1) day(-1)), and were followed for 5 years. The participants and investigators were not blinded to the assignment. The primary outcomes were the annual change in estimated GFR and creatinine clearance, the incidence of doubling of serum creatinine and the time to doubling of baseline serum creatinine. The study was completed by 47 (84%) of 56 participants in the low-protein diet group and 41 (73%) of 56 participants in the normal-diet group. During the study period, the difference in mean annual change in estimated GFR between the low-protein diet and the normal-protein diet groups was -0.3 ml min(-1) 1.73 m(-2) (95% CI -3.9, 4.4; p = 0.93). The difference in mean annual change in creatinine clearance between the low-protein diet and the normal-protein diet groups was -0.006 ml s(-1) 1.73 m(-2) (95% CI -0.089, 0.112; p = 0.80). A doubling of serum creatinine was reached in 16 patients of the low-protein group (34.0%), compared with 15 in the normal-protein group (36.6%), the difference between groups being -2.6% (95% CI -22.6, 17.5; p = 0.80). The time to doubling of serum creatinine was similar in both groups (p = 0.66). It is extremely difficult to get patients to follow a long-term low-protein diet. Although in the low-protein group overall protein intake was slightly (but not significantly) lower, it did not confer renoprotection. ClinicalTrials.gov NCT00448526. Research grant from the Ministry of Health, Labour and Welfare of Japan.
First annual report SHRP C103 task 4 : rapid repair techniques.
DOT National Transportation Integrated Search
1989-01-01
The objective of task four is to develop technically and economically feasible methods of concrete bridge deck protection, rehabilitation, and replacement. The objective of the task will be accomplished through a progression of six subtasks. The subt...
King, Alex
2018-05-07
In his third-annual State of the Lab address, Ames Laboratory Director Alex King called the past year one of "quiet but strong progress" and called for Ames Laboratory to continue to build on its strengths while responding to changing expectations for energy research.
Presentation of Institutional Results Reports, 2001.
ERIC Educational Resources Information Center
Illinois State Board of Higher Education, Springfield.
"The Illinois Commitment: Partnerships, Opportunities, and Excellence" requires an annual submission of a Results Report from higher education institutions and agencies to provide evidence of progress toward the six statewide goals: economic growth, teaching and learning, affordability, access and diversity, high expectations and…
DOE Office of Scientific and Technical Information (OSTI.GOV)
King, Alex
2010-01-01
In his third-annual State of the Lab address, Ames Laboratory Director Alex King called the past year one of "quiet but strong progress" and called for Ames Laboratory to continue to build on its strengths while responding to changing expectations for energy research.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Morgan, O.B. Jr.; Berry, L.A.; Sheffield, J.
This annual report on fusion energy discusses the progress on work in the following main topics: toroidal confinement experiments; atomic physics and plasma diagnostics development; plasma theory and computing; plasma-materials interactions; plasma technology; superconducting magnet development; fusion engineering design center; materials research and development; and neutron transport. (LSP)
First Annual Symposium. Volume 1: Plenary Session
NASA Technical Reports Server (NTRS)
1989-01-01
Presentations from the symposium are presented. The progress of the Center for Space Construction is reviewed to promote technology transfer from the University of Colorado at Boulder to the national aerospace community. This symposium was heavily weighted toward plans and methodology.
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
1961-10-31
Research facilities, general construction progress, research activities, and administration are discussed and a financial statement is given. Fairly detailed accounts are given of research programs in the fields of physics, accelerator development, instrumentation, applied mathematics, chemistry, nuclear engineering, biology, and medicine. (M.C.G.)
Fuel Cell Buses in U.S. Transit Fleets: Current Status 2017
DOT National Transportation Integrated Search
2017-11-01
This report, published annually, summarizes the progress of fuel cell electric bus (FCEB) development in the United States and discusses the achievements and challenges of introducing fuel cell propulsion in transit. The report provides a summary of ...
Fuel Cell Buses in U.S. Transit Fleets: Current Status 2016
DOT National Transportation Integrated Search
2016-11-01
This report, published annually, summarizes the progress of fuel cell electric bus (FCEB) development in the United States and discusses the achievements and challenges of introducing fuel cell propulsion in transit. The report provides a summary of ...
NASA Technical Reports Server (NTRS)
Duric, Nebojsa
1992-01-01
The emission components of spiral galaxies between 12 microns and 90 cm are identified. Additionally, an attempt to understand the relationships between them was made. The specific goal was to gain some understanding on the nature of the radio-infrared correlation. The results are summarized.
UAS Integration in the NAS Project - FY 14 Annual Review
NASA Technical Reports Server (NTRS)
Grindle, Laurie; Randall, Debra; Hackenberg, Davis
2014-01-01
This briefing gives insight into the research activities and efforts being executed in order to integrate unmanned aircraft systems into the national airspace system. This briefing is to inform others of the UAS-NAS Projects progress and future directions.
Fuel Cell Buses in U.S. Transit Fleets : Current Status 2015
DOT National Transportation Integrated Search
2015-12-01
This report, published annually, summarizes the progress of fuel cell electric bus (FCEB) development in the United States and discusses the achievements and challenges of introducing fuel cell propulsion in transit. The report provides a summary of ...
FY2009 Annual Progress Report for Energy Storage Research and Development
DOE Office of Scientific and Technical Information (OSTI.GOV)
none,
2010-01-19
The energy storage research and development effort within the VT Program is responsible for researching and improving advanced batteries and ultracapacitors for a wide range of vehicle applications, including HEVs, PHEVs, EVs, and fuel cell vehicles (FCVs).
Waste Isolation Pilot Plant Annual Site Environmental Report for 2014. Emended
DOE Office of Scientific and Technical Information (OSTI.GOV)
none,
2015-09-01
The purpose of the Waste Isolation Pilot Plant (WIPP) Annual Site Environmental Report for 2014 (ASER) is to provide information required by U.S. Department of Energy (DOE) Order 231.1B, Environment, Safety, and Health Reporting. Specifically, the ASER presents summary environmental data to: Characterize site environmental management performance; Summarize environmental occurrences and responses reported during the calendar year (CY); Confirm compliance with environmental standards and requirements; Highlight significant environmental accomplishments, including progress toward the DOE environmental sustainability goals made through implementation of the WIPP Environmental Management System (EMS).
Electric and Hybrid Vehicles Program. Sixteenth annual report to Congress for fiscal year 1992
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1993-08-01
This report describes the progress achieved in developing electric and hybrid vehicle technologies, beginning with highlights of recent accomplishments in FY 1992. Detailed descriptions are provided of program activities during FY 1992 in the areas of battery, fuel cell, and propulsion system development, and testing and evaluation of new technology in fleet site operations and in laboratories. This Annual Report also contains a status report on incentives and use of foreign components, as well as a list of publications resulting from the DOE program.
Physics of the Cosmos Program Annual Technology Report
NASA Technical Reports Server (NTRS)
Pham, Bruce Thai; Cardiff, Ann H.
2015-01-01
What's in this Report? What's New? This fifth Program Annual Technology Report (PATR) summarizes the Programs technology development activities for fiscal year (FY) 2015. The PATR serves four purposes.1. Summarize the technology gaps identified by the astrophysics community;2. Present the results of this years technology gap prioritization by the PCOS Technology Management Board (TMB);3. Report on newly funded PCOS Strategic Astrophysics Technology (SAT) projects; and4. Detail progress, current status, and activities planned for the coming year for all technologies supported by PCOS Supporting Research and Technology (SRT) funding in FY 2015. .
ERIC Educational Resources Information Center
Pigozzi, Mary Joy
This report describes the clearinghouse activities of the Non-Formal Education (NFE) Information Center from September 1981 through August 1982 and details efforts to strengthen the capacity of selected NFE resource centers in Africa, Asia, and Latin America. It first addresses the decision to extend the NFE Network Project, and then turns to the…
Kar, Shantanu K; Dwibedi, Bhagirathi; Das, Birendra K; Agrawala, Bikash K; Ramachandran, Cherubala P; Horton, John
2017-10-01
Once interruption of transmission of lymphatic filariasis is achieved, morbidity prevention and management becomes more important. A study in Brugia malayi filariasis from India has shown sub-clinical lymphatic pathology with potential reversibility. We studied a Wuchereria bancrofti infected population, the major contributor to LF globally. Children aged 5-18 years from Odisha, India were screened for W. bancrofti infection and disease. 102 infected children, 50 with filarial disease and 52 without symptoms were investigated by lymphoscintigraphy and then randomized to receive a supervised single oral dose of DEC and albendazole which was repeated either annually or semi-annually. The lymphatic pathology was evaluated six monthly for two years. Baseline lymphoscintigraphy showed abnormality in lower limb lymphatics in 80% of symptomatic (40/50) and 63·5% (33/52) of asymptomatic children. Progressive improvement in baseline pathology was seen in 70·8, 87·3, 98·6, and 98·6% of cases at 6, 12, 18, and 24 months follow up, while in 4·2, 22·5, 47·9 and 64·8%, pathology reverted to normal. This was independent of age (p = 0·27), symptomatic status (p = 0·57) and semi-annual/bi-annual dosing (p = 0·46). Six of eleven cases showed clinical reduction in lymphedema of legs. A significant proportion of a young W. bancrofti infected population exhibited lymphatic pathology which was reversible with annual dosage of DEC and albendazole. This provides evidence for morbidity prevention & treatment of early lymphedema. It can also be used as a tool to improve community compliance during mass drug administration. ClinicalTrials.gov No CTRI/2013/10/004121.
Sengupta, Anamika; Kumar Maitra, Saumen
2006-01-01
The role of the pineal gland and its hormone melatonin in the regulation of annual testicular events was investigated for the first time in a psittacine bird, the roseringed parakeet (Psittacula krameri). Accordingly, the testicular responsiveness of the birds was evaluated following surgical pinealectomy with or without the exogenous administration of melatonin and the experimental manipulations of the endogenous levels of melatonin through exposing the birds to continuous illumination. An identical schedule was followed during the four reproductive phases, each characterizing a distinct testicular status in the annual cycle, namely, the phases of gametogenic quiescence (preparatory phase), seasonal recovery of gametogenesis (progressive phase), seasonal initiation of sperm formation (pre-breeding phase), and peak gametogenic activity (breeding phase). In each reproductive phase, the birds were subjected to various experimental conditions, and the effects were studied comparing the testicular conditions in the respective control birds. The study included germ cell profiles of the seminiferous tubules, the activities of steroidogenic enzymes 17beta-hydroxysteroid dehydrogenase (17beta-HSD), and Delta(5)3beta-hydroxysteroid dehydrogenase (Delta(5)3beta- HSD) in the testis, and the serum levels of testosterone and melatonin. An analysis of the data reveals that the pineal gland and its hormone melatonin may play an inhibitory role in the development of the testis until the attainment of the seasonal peak in the annual reproductive cycle. However, in all probability, the termination of the seasonal activity of the testis or the initiation of testicular regression in the annual reproductive cycle appears to be the function of the pineal gland, but not of melatonin.
Karim-Kos, Henrike E; Hackl, Monika; Mann, Georg; Urban, Christian; Woehrer, Adelheid; Slavc, Irene; Ladenstein, Ruth
2016-06-01
This is the first study on trends in cancer incidence, survival and mortality for children and adolescents in Austria. The aim was to assess to what extent progress against childhood and adolescent cancer has been made in Austria since the 1990s and to complement the childhood and adolescent cancer trends for Central Europe. All malignant neoplasms and non-malignant tumours of the Central Nervous System (CNS) in patients aged less than 20 years and diagnosed between 1994 and 2011 (N=5425) were derived from the Austrian National Cancer Registry (ANCR). Incidence and mortality trends were evaluated by the average annual percentage change (AAPC). Observed survival rates were calculated based on follow-up until December 31st 2013. Childhood cancer remained stable with 182 cases per million in 2011, but rose among girls by 1.4% (95% CI: .1, 3.6) annually due to an increase of non-malignant CNS tumours and Non-Hodgkin lymphoma. Adolescent cancer rose by 1.5% (95% CI: .4, 2.6) annually, from 182 cases per million in 1994-269 in 2011, especially leukaemia, CNS tumours (including non-malignant types) and epithelial tumours. Five-year survival improved by 5-7% reaching 86% for both groups (p<.05). Mortality declined by -2.4% (95% CI: -3.7, -1.2) and -2.0% (95% CI: -4.6, .5), respectively, especially for childhood leukaemia. Progress is demonstrated by improved survival and declined mortality most likely related to improved diagnostic techniques, more effective therapeutic regimes, supportive care and a central advisory function of experts in the Austrian paediatric oncology. Copyright © 2016 Elsevier Ltd. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Stull, R.B.
1993-08-27
This document is a progress report to the USDOE Atmospheric Radiation and Measurement Program (ARM). The overall project goal is to relate subgrid-cumulus-cloud formation, coverage, and population characteristics to statistical properties of surface-layer air, which in turn are modulated by heterogeneous land-usage within GCM-grid-box-size regions. The motivation is to improve the understanding and prediction of climate change by more accurately describing radiative and cloud processes.
1990-10-01
granulomE , Arch. Dermatol., (in press). Low, G. J. Ionizing radiation-induced pemphigus. Arch. Dermatol., (in press). McCollough, M. L. Dominant...the severity of their headache on a linear pain scale as well as a verbal scale. Patients were questioned as to whether they had received medications...occurred either by phone or in the Neurologist’s office, using the same verbal and linear scales. Progress: In all, six patients were entered into the
Why Do Medial Unicompartmental Knee Arthroplasties Fail Today?
van der List, Jelle P; Zuiderbaan, Hendrik A; Pearle, Andrew D
2016-05-01
Failure rates are higher in medial unicompartmental knee arthroplasty (UKA) than total knee arthroplasty. To improve these failure rates, it is important to understand why medial UKA fail. Because individual studies lack power to show failure modes, a systematic review was performed to assess medial UKA failure modes. Furthermore, we compared cohort studies with registry-based studies, early with midterm and late failures and fixed-bearing with mobile-bearing implants. Databases of PubMed, EMBASE, and Cochrane and annual registries were searched for medial UKA failures. Studies were included when they reported >25 failures or when they reported early (<5 years), midterm (5-10 years), or late failures (>10 years). Thirty-seven cohort studies (4 level II studies and 33 level III studies) and 2 registry-based studies were included. A total of 3967 overall failures, 388 time-dependent failures, and 1305 implant design failures were identified. Aseptic loosening (36%) and osteoarthritis (OA) progression (20%) were the most common failure modes. Aseptic loosening (26%) was most common early failure mode, whereas OA progression was more commonly seen in midterm and late failures (38% and 40%, respectively). Polyethylene wear (12%) and instability (12%) were more common in fixed-bearing implants, whereas pain (14%) and bearing dislocation (11%) were more common in mobile-bearing implants. This level III systematic review identified aseptic loosening and OA progression as the major failure modes. Aseptic loosening was the main failure mode in early years and mobile-bearing implants, whereas OA progression caused most failures in late years and fixed-bearing implants. Copyright © 2016 Elsevier Inc. All rights reserved.
NASA Technical Reports Server (NTRS)
1995-01-01
This report contains the 1995 annual progress reports of the Research Fellows and students of the Center for Turbulence Research (CTR). In 1995 CTR continued its concentration on the development and application of large-eddy simulation to complex flows, development of novel modeling concepts for engineering computations in the Reynolds averaged framework, and turbulent combustion. In large-eddy simulation, a number of numerical and experimental issues have surfaced which are being addressed. The first group of reports in this volume are on large-eddy simulation. A key finding in this area was the revelation of possibly significant numerical errors that may overwhelm the effects of the subgrid-scale model. We also commissioned a new experiment to support the LES validation studies. The remaining articles in this report are concerned with Reynolds averaged modeling, studies of turbulence physics and flow generated sound, combustion, and simulation techniques. Fundamental studies of turbulent combustion using direct numerical simulations which started at CTR will continue to be emphasized. These studies and their counterparts carried out during the summer programs have had a noticeable impact on combustion research world wide.
Pine Gene Discovery Project - Final Report - 08/31/1997 - 02/28/2001
DOE Office of Scientific and Technical Information (OSTI.GOV)
Whetten, R. W.; Sederoff, R. R.; Kinlaw, C.
2001-04-30
Integration of pines into the large scope of plant biology research depends on study of pines in parallel with study of annual plants, and on availability of research materials from pine to plant biologists interested in comparing pine with annual plant systems. The objectives of the Pine Gene Discovery Project were to obtain 10,000 partial DNA sequences of genes expressed in loblolly pine, to determine which of those pine genes were similar to known genes from other organisms, and to make the DNA sequences and isolated pine genes available to plant researchers to stimulate integration of pines into the widermore » scope of plant biology research. Those objectives have been completed, and the results are available to the public. Requests for pine genes have been received from a number of laboratories that would otherwise not have included pine in their research, indicating that progress is being made toward the goal of integrating pine research into the larger molecular biology research community.« less
Age of onset of myopia predicts risk of high myopia in later childhood in myopic Singapore children.
Chua, Sharon Y L; Sabanayagam, Charumathi; Cheung, Yin-Bun; Chia, Audrey; Valenzuela, Robert K; Tan, Donald; Wong, Tien-Yin; Cheng, Ching-Yu; Saw, Seang-Mei
2016-07-01
To investigate the effect of age of myopia onset on the severity of myopia later in life among myopic children. In this prospective study, school children aged 7-9 years from the Singapore Cohort Of the Risk factors for Myopia (SCORM) were followed up till 11 years (n = 928). Age of myopia onset was defined either through questionnaire at baseline (age 7-9 years) or subsequent annual follow-up visits. Age of onset of myopia was a surrogate indicator of duration of myopia progression till age 11 years. Cycloplegic refraction and axial length were measured at every annual eye examination. High myopia was defined as spherical equivalent of ≤-5.0 D. A questionnaire determined the other risk factors. In multivariable regression models, younger age of myopia onset (per year decrease) or longer duration of myopia progression was associated with high myopia (odds ratio (OR) = 2.86; 95% CI: 2.39 to 3.43), more myopic spherical equivalent (regression coefficient (β) = -0.86 D; 95% CI: -0.93 to -0.80) and longer axial length (β = 0.28 mm; 95% CI: 0.24 to 0.32) at aged 11 years, after adjusting for gender, race, school, books per week and parental myopia. In Receiver Operating Curve (ROC) analyses, age of myopia onset alone predicted high myopia by 85% (area under the curve = 0.85), while the addition of other factors including gender, race, school, books per week and parental myopia only marginally improved this prediction (area under the curve = 0.87). Age of myopia onset or duration of myopia progression was the most important predictor of high myopia in later childhood in myopic children. Future trials to retard the progression of myopia to high myopia could focus on children with younger age of myopia onset or with longer duration of myopia progression. © 2016 The Authors Ophthalmic & Physiological Optics © 2016 The College of Optometrists.