Volume 51, Issue 7-8, Pages 639-896(July 2003)
Preface
Preface
NASA Astrophysics Data System (ADS)
Andreev, O.
2003-07-01
We briefly review a possible scheme for getting the known QCD scaling laws within string theory. In particular, we consider amplitudes for exclusive scattering of hadrons at large momentum transfer and hadronic form factors.
Confinement of surface waves at the air-water interface to control aerosol size and dispersity
NASA Astrophysics Data System (ADS)
Nazarzadeh, Elijah; Wilson, Rab; King, Xi; Reboud, Julien; Tassieri, Manlio; Cooper, Jonathan M.
2017-11-01
The precise control over the size and dispersity of droplets, produced within aerosols, is of great interest across many manufacturing, food, cosmetic, and medical industries. Amongst these applications, the delivery of new classes of high value drugs to the lungs has recently attracted significant attention from pharmaceutical companies. This is commonly achieved through the mechanical excitation of surface waves at the air liquid interface of a parent liquid volume. Previous studies have established a correlation between the wavelength on the surface of liquid and the final aerosol size. In this work, we show that the droplet size distribution of aerosols can be controlled by constraining the liquid inside micron-sized cavities and coupling surface acoustic waves into different volumes of liquid inside micro-grids. In particular, we show that by reducing the characteristic physical confinement size (i.e., either the initial liquid volume or the cavities' diameters), higher harmonics of capillary waves are revealed with a consequent reduction of both aerosol mean size and dispersity. In doing so, we provide a new method for the generation and fine control of aerosols' sizes distribution.
NASA Technical Reports Server (NTRS)
Shu, Chi-Wang
2004-01-01
This project is about the investigation of the development of the discontinuous Galerkin finite element methods, for general geometry and triangulations, for solving convection dominated problems, with applications to aeroacoustics. Other related issues in high order WENO finite difference and finite volume methods have also been investigated. methods are two classes of high order, high resolution methods suitable for convection dominated simulations with possible discontinuous or sharp gradient solutions. In [18], we first review these two classes of methods, pointing out their similarities and differences in algorithm formulation, theoretical properties, implementation issues, applicability, and relative advantages. We then present some quantitative comparisons of the third order finite volume WENO methods and discontinuous Galerkin methods for a series of test problems to assess their relative merits in accuracy and CPU timing. In [3], we review the development of the Runge-Kutta discontinuous Galerkin (RKDG) methods for non-linear convection-dominated problems. These robust and accurate methods have made their way into the main stream of computational fluid dynamics and are quickly finding use in a wide variety of applications. They combine a special class of Runge-Kutta time discretizations, that allows the method to be non-linearly stable regardless of its accuracy, with a finite element space discretization by discontinuous approximations, that incorporates the ideas of numerical fluxes and slope limiters coined during the remarkable development of the high-resolution finite difference and finite volume schemes. The resulting RKDG methods are stable, high-order accurate, and highly parallelizable schemes that can easily handle complicated geometries and boundary conditions. We review the theoretical and algorithmic aspects of these methods and show several applications including nonlinear conservation laws, the compressible and incompressible Navier-Stokes equations, and Hamilton-Jacobi-like equations.
Perfluorotributylamine: A novel long-lived greenhouse gas
NASA Astrophysics Data System (ADS)
Hong, Angela C.; Young, Cora J.; Hurley, Michael D.; Wallington, Timothy J.; Mabury, Scott A.
2013-11-01
Perfluorinated compounds impact the Earth's radiative balance. Perfluorotributylamine (PFTBA) belongs to the perfluoroalkyl amine class of compounds; these have not yet been investigated as long-lived greenhouse gases (LLGHGs). Atmospheric measurements of PFTBA made in Toronto, ON, detected a mixing ratio of 0.18 parts per trillion by volume. An instantaneous radiative efficiency of 0.86 W m-2 ppb-1 was calculated from its IR absorption spectra, and a lower limit of 500 years was estimated for its atmospheric lifetime. PFTBA has the highest radiative efficiency of any compound detected in the atmosphere. If the concentration in Toronto is representative of the change in global background concentration since the preindustrial period, then the radiative forcing of PFTBA is 1.5 × 10-4 W m-2. We calculate the global warming potential of PFTBA over a 100 year time horizon to be 7100. Detection of PFTBA demonstrates that perfluoroalkyl amines are a class of LLGHGs worthy of future study.
Routen, Ash C; Biddle, Stuart J H; Bodicoat, Danielle H; Cale, Lorraine; Clemes, Stacy; Edwardson, Charlotte L; Glazebrook, Cris; Harrington, Deirdre M; Khunti, Kamlesh; Pearson, Natalie; Salmon, Jo; Sherar, Lauren B
2017-01-01
Introduction Children engage in a high volume of sitting in school, particularly in the classroom. A number of strategies, such as physically active lessons (termed movement integration (MI)), have been developed to integrate physical activity into this learning environment; however, no single approach is likely to meet the needs of all pupils and teachers. This protocol outlines an implementation study of a primary school-based MI intervention: CLASS PAL (Physically Active Learning) programme. This study aims to (A) determine the degree of implementation of CLASS PAL, (B) identify processes by which teachers and schools implement CLASS PAL and (C) investigate individual (pupil and teacher) level and school-level characteristics associated with implementation of CLASS PAL. Methods and analysis The intervention will provide teachers with a professional development workshop and a bespoke teaching resources website. The study will use a single group before-and-after design, strengthened by multiple interim measurements. Six state-funded primary schools will be recruited within Leicestershire, UK. Evaluation data will be collected prior to implementation and at four discrete time points during implementation: At measurement 0 (October 2016), school, teacher and pupil characteristics will be collected. At measurements 0 and 3 (June–July 2017), accelerometry, cognitive functioning, self-reported sitting and classroom engagement data will be collected. At measurements 1(December 2016–March 2017) and 3, teacher interviews (also at measurement 4; September–October 2017) and pupil focus groups will be conducted, and at measurements 1 and 2 (April–May 2017), classroom observations. Implementation will be captured through website analytics and ongoing teacher completed logs. Ethics and dissemination Ethical approval was obtained through the Loughborough University Human Participants Ethics Sub-Committee (Reference number: R16-P115). Findings will be disseminated via practitioner and/or research journals and to relevant regional and national stakeholders through print and online media and dissemination event(s). PMID:29122808
The training intensity distribution among well-trained and elite endurance athletes
Stöggl, Thomas L.; Sperlich, Billy
2015-01-01
Researchers have retrospectively analyzed the training intensity distribution (TID) of nationally and internationally competitive athletes in different endurance disciplines to determine the optimal volume and intensity for maximal adaptation. The majority of studies present a “pyramidal” TID with a high proportion of high volume, low intensity training (HVLIT). Some world-class athletes appear to adopt a so-called “polarized” TID (i.e., significant % of HVLIT and high-intensity training) during certain phases of the season. However, emerging prospective randomized controlled studies have demonstrated superior responses of variables related to endurance when applying a polarized TID in well-trained and recreational individuals when compared with a TID that emphasizes HVLIT or threshold training. The aims of the present review are to: (1) summarize the main responses of retrospective and prospective studies exploring TID; (2) provide a systematic overview on TIDs during preparation, pre-competition, and competition phases in different endurance disciplines and performance levels; (3) address whether one TID has demonstrated greater efficacy than another; and (4) highlight research gaps in an effort to direct future scientific studies. PMID:26578968
The training intensity distribution among well-trained and elite endurance athletes.
Stöggl, Thomas L; Sperlich, Billy
2015-01-01
Researchers have retrospectively analyzed the training intensity distribution (TID) of nationally and internationally competitive athletes in different endurance disciplines to determine the optimal volume and intensity for maximal adaptation. The majority of studies present a "pyramidal" TID with a high proportion of high volume, low intensity training (HVLIT). Some world-class athletes appear to adopt a so-called "polarized" TID (i.e., significant % of HVLIT and high-intensity training) during certain phases of the season. However, emerging prospective randomized controlled studies have demonstrated superior responses of variables related to endurance when applying a polarized TID in well-trained and recreational individuals when compared with a TID that emphasizes HVLIT or threshold training. The aims of the present review are to: (1) summarize the main responses of retrospective and prospective studies exploring TID; (2) provide a systematic overview on TIDs during preparation, pre-competition, and competition phases in different endurance disciplines and performance levels; (3) address whether one TID has demonstrated greater efficacy than another; and (4) highlight research gaps in an effort to direct future scientific studies.
Inkjet Printing of Drug-Loaded Mesoporous Silica Nanoparticles-A Platform for Drug Development.
Wickström, Henrika; Hilgert, Ellen; Nyman, Johan O; Desai, Diti; Şen Karaman, Didem; de Beer, Thomas; Sandler, Niklas; Rosenholm, Jessica M
2017-11-21
Mesoporous silica nanoparticles (MSNs) have shown great potential in improving drug delivery of poorly water soluble (BCS class II, IV) and poorly permeable (BCS class III, IV) drugs, as well as facilitating successful delivery of unstable compounds. The nanoparticle technology would allow improved treatment by reducing adverse reactions of currently approved drugs and possibly reintroducing previously discarded compounds from the drug development pipeline. This study aims to highlight important aspects in mesoporous silica nanoparticle (MSN) ink formulation development for digital inkjet printing technology and to advice on choosing a method (2D/3D) for nanoparticle print deposit characterization. The results show that both unfunctionalized and polyethyeleneimine (PEI) surface functionalized MSNs, as well as drug-free and drug-loaded MSN-PEI suspensions, can be successfully inkjet-printed. Furthermore, the model BCS class IV drug remained incorporated in the MSNs and the suspension remained physically stable during the processing time and steps. This proof-of-concept study suggests that inkjet printing technology would be a flexible deposition method of pharmaceutical MSN suspensions to generate patterns according to predefined designs. The concept could be utilized as a versatile drug screening platform in the future due to the possibility of accurately depositing controlled volumes of MSN suspensions on various materials.
Entropy Inequality Violations from Ultraspinning Black Holes.
Hennigar, Robie A; Mann, Robert B; Kubizňák, David
2015-07-17
We construct a new class of rotating anti-de Sitter (AdS) black hole solutions with noncompact event horizons of finite area in any dimension and study their thermodynamics. In four dimensions these black holes are solutions to gauged supergravity. We find that their entropy exceeds the maximum implied from the conjectured reverse isoperimetric inequality, which states that for a given thermodynamic volume, the black hole entropy is maximized for Schwarzschild-AdS space. We use this result to suggest more stringent conditions under which this conjecture may hold.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Velec, Michael; Haddad, Carol R.; Craig, Tim
Purpose: To identify risk factors associated with a decline in liver function after stereotactic body radiation therapy (SBRT) for hepatocellular carcinoma. Methods and Materials: Data were analyzed from patients with hepatocellular carcinoma treated on clinical trials of 6-fraction SBRT. Liver toxicity was defined as an increase in Child-Pugh (CP) score ≥2 three months after SBRT. Clinical factors, SBRT details, and liver dose-volume histogram (DVH) parameters were tested for association with toxicity using logistic regression. CP class B patients were analyzed separately. Results: Among CP class A patients, 101 were evaluable, with a baseline score of A5 (72%) or A6 (28%).more » Fifty-three percent had portal vein thrombus. The median liver volume was 1286 cc (range, 766-3967 cc), and the median prescribed dose was 36 Gy (range, 27-54 Gy). Toxicity was seen in 26 patients (26%). Thrombus, baseline CP of A6, and lower platelet count were associated with toxicity on univariate analysis, as were several liver DVH-based parameters. Absolute and spared liver volumes were not significant. On multivariate analysis for CP class A patients, significant associations were found for baseline CP score of A6 (odds ratio [OR], 4.85), lower platelet count (OR, 0.90; median, 108 × 10{sup 9}/L vs 150 × 10{sup 9}/L), higher mean liver dose (OR, 1.33; median, 16.9 Gy vs 14.7 Gy), and higher dose to 800 cc of liver (OR, 1.11; median, 14.3 Gy vs 6.0 Gy). With 13 CP-B7 patients included or when dose to 800 cc of liver was replaced with other DVH parameters (eg, dose to 700 or 900 cc of liver) in the multivariate analysis, effective volume and portal vein thrombus were associated with an increased risk. Conclusions: Baseline CP scores and higher liver doses (eg, mean dose, effective volume, doses to 700-900 cc) were strongly associated with liver function decline 3 months after SBRT. A lower baseline platelet count and portal vein thrombus were also associated with an increased risk.« less
Raju, Seshadri; Ward, Mark; Jones, Tamekia L
2015-01-01
Quantification of reflux is desirable in advanced chronic venous disease as clinical features are based on its adverse impact on ambulatory venous pressure (AMVP). Prior clinical observation suggests that reflux in a saphenous vein > 5 mm is likely significant. On the basis of normal calf pump mechanics, we hypothesized that a reflux volume ≥ 30 mL was necessary to upset pump equilibrium. Venous laboratory data in 119 limbs with isolated saphenous reflux were analyzed. Reflux volume was calculated by duplex ultrasound (area × velocity × duration). The relationship of reflux volume to saphenous size, calf pump function (air plethysmography, AMVP), flow resistance (Poiseuille equation), and clinical severity were examined. Saphenous size had a bimodal relationship to reflux volume. Reflux volume of ≥ 30 mL occurred mostly (97% of limbs) with saphenous size of ≥ 5.5 mm, but 51% of saphenous veins >5.5 mm had reflux volumes <30 mL. This is because saphenous veins invariably carried less than their maximum reflux potential indicated by their size (Poiseuille equation). Variable additional focal resistance across refluxive valve cusps and narrower re-entry perforators is not taken into account when only saphenous truncal size is used for resistance calculation. Furthermore, the association of AMVP with reflux was found not to be based on a set (≥ 30 mL) threshold but was variable, depending on existing calf pump mechanics, compensatory in some (12% of limbs) and aggravating reflux effects in others (26%). Calf pump abnormalities were found in 70% of refluxive limbs and in 44% (n = 16) of contralateral limbs without any reflux. Reflux volume was significantly higher overall in limbs with ulcer (C6), but the range overlapped with lesser clinical classes. Seven of 14 limbs with active ulcers had reflux volume >30 mL; six of seven limbs with active ulcers and reflux volume of <30 mL had calf pump abnormalities that would be poorly tolerant of reflux even at these smaller volumes. Saphenous size alone cannot be used as an indicator of significant reflux. More than two thirds of the limbs with isolated saphenous reflux have calf pump abnormalities, which also occurred without reflux in the opposite limb--a novel finding. This means that in addition to quantification of reflux volume, calf pump assessment such as with air plethysmography and AMVP is desirable in clinical classes 3 and higher for proper assessment. Copyright © 2015 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.
BROMINATED FLAME RETARDANTS: WHAT WE KNOW, AND WHAT WE DON�T
Brominated flame retardants (BFRs) represent a large and diverse class of high volume industrial chemicals which have been developed to provide fire safety. There are many other BFRs which have been used and are under development. Historically, polybrominated biphenyls (PBBs) w...
ERIC Educational Resources Information Center
International Federation for Documentation, The Hague (Netherlands). Committee on Classification Research.
In continuation of the "Cumulated UDC Supplement - 1964" published by the International Federation for Documentation, this document provides a cumulative supplement to the Universal Decimal Classification for 1965-1975. This third of five volumes lists new classification subdivisions in the following subject areas: (1) medical sciences; (2)…
1986-02-01
Data-for ASsessingHealthRISKS In Potential Theaters ~ of Operation forU,5. Mil-itary._orces. Jf-jr cLAss t:cAToN 9; r-.$ ’AGg UNCLASSIFIED Volume 7...Bypass, Potable-Water Disinfection,_ and Water-Quality Analysis Techniques; and Vol. 9, Data for Assessing Health Risks in Potential Theaters of Operation ...cleaning the RO elements, with objectives of improving solute rejection and reducing operating pressure. The most common method is to flush citric acid
Engelberger, Rolf P; Blazek, Claudia; Amsler, Felix; Keo, Hong H; Baumann, Frédéric; Blättler, Werner; Baumgartner, Iris; Willenberg, Torsten
2011-10-05
Leg edema is a common manifestation of various underlying pathologies. Reliable measurement tools are required to quantify edema and monitor therapeutic interventions. Aim of the present work was to investigate the reproducibility of optoelectronic leg volumetry over 3 weeks' time period and to eliminate daytime related within-individual variability. Optoelectronic leg volumetry was performed in 63 hairdressers (mean age 45 ± 16 years, 85.7% female) in standing position twice within a minute for each leg and repeated after 3 weeks. Both lower leg (legBD) and whole limb (limbBF) volumetry were analysed. Reproducibility was expressed as analytical and within-individual coefficients of variance (CVA, CVW), and as intra-class correlation coefficients (ICC). A total of 492 leg volume measurements were analysed. Both legBD and limbBF volumetry were highly reproducible with CVA of 0.5% and 0.7%, respectively. Within-individual reproducibility of legBD and limbBF volumetry over a three weeks' period was high (CVW 1.3% for both; ICC 0.99 for both). At both visits, the second measurement revealed a significantly higher volume compared to the first measurement with a mean increase of 7.3 ml ± 14.1 (0.33% ± 0.58%) for legBD and 30.1 ml ± 48.5 ml (0.52% ± 0.79%) for limbBF volume. A significant linear correlation between absolute and relative leg volume differences and the difference of exact day time of measurement between the two study visits was found (P < .001). A therefore determined time-correction formula permitted further improvement of CVW. Leg volume changes can be reliably assessed by optoelectronic leg volumetry at a single time point and over a 3 weeks' time period. However, volumetry results are biased by orthostatic and daytime-related volume changes. The bias for day-time related volume changes can be minimized by a time-correction formula.
Popcorn: An Explosive Mixture of General Mathematics.
ERIC Educational Resources Information Center
Westerberg, Judy; Whiting, Jack
1992-01-01
Presents an activity developed for back-to-back general science and mathematics classes involving measurement, data analysis, and consumer mathematics. Students compare brands of popcorn for number of popped and unpopped kernels, volume, size, color, texture, and flavor, and develop advertisements for the best brands. Suggests possible extension…
USA Track & Field Coaching Manual. USA Track & Field.
ERIC Educational Resources Information Center
USA Track and Field, Inc., Indianapolis, IN.
This book presents comprehensive, ready-to-apply information from 33 world-class coaches and experts about major track and field events for high school and college coaches. The volume features proven predictive testing procedures; detailed event-specific technique instruction; carefully crafted training programs; and preparation and performance…
7 CFR 985.55 - Identification.
Code of Federal Regulations, 2010 CFR
2010-01-01
... HANDLING OF SPEARMINT OIL PRODUCED IN THE FAR WEST Order Regulating Handling Volume Limitations § 985.55 Identification. (a) Each producer shall, under supervision of the Committee, identify each class of oil within 15... approval of the Secretary. Identification of oil shall be accomplished before its delivery either to a...
Cable Television: Franchising Considerations.
ERIC Educational Resources Information Center
Baer, Walter S.; And Others
This volume is a comprehensive reference guide to cable television technology and issues of planning, franchising, and regulating a cable system. It is intended for local government officials and citizens concerned with the development of cable television systems in their communities, as well as for college and university classes in…
21 CFR 864.5600 - Automated hematocrit instrument.
Code of Federal Regulations, 2012 CFR
2012-04-01
... measures the packed red cell volume of a blood sample to distinguish normal from abnormal states, such as anemia and erythrocytosis (an increase in the number of red cells). (b) Classification. Class II... § 864.5600 Automated hematocrit instrument. (a) Identification. An automated hematocrit instrument is a...