SUPERFUND TREATABILITY CLEARINGHOUSE: SOIL STABILIZATION PILOT STUDY, UNITED CHROME NPL SITE PILOT STUDY AND HEALTH AND SAFETY PROGRAM, UNITED CHROME NPL SITE PILOT STUDY

EPA Science Inventory

This document is a project plan for a pilot study at the United Chrome NPL site, Corvallis, Oregon and includes the health and safety and quality assurance/quality control plans. The plan reports results of a bench-scale study of the treatment process as iieasured by the ...

Blood donor show behaviour after an invitation to donate: The influence of collection site factors.

PubMed

Merz, E-M; Zijlstra, B J H; de Kort, W L A M

2017-10-01

Show behaviour after invitation to donate varies considerably across donors. More insight into this variation is important for blood banks in achieving stable stocks. This study examined individual factors determining intended show behaviour. Most importantly, however, this study is the first study to account for variation in donor behaviour across different collection sites. We applied a multilevel approach to data from Donor InSight, including 11 889 donors from 257 fixed and mobile collection sites in the Netherlands. The aim of the multilevel models was to account for variance at two levels, that is donors and collection sites. We estimated the likelihood of showing after invitation based on individual predictors, including demographics, donation history and attitude. At the collection site level, we included satisfaction with the blood bank aggregated from individual responses by donors who donate at this site, opening hours and collection site type, that is fixed/mobile. Most importantly, show behaviour varied considerably across collection sites and depended on characteristics of these sites. Moreover, women, older and more experienced donors had higher odds of showing after invitation than men, younger and less experienced donors. Donors higher on warm glow, self-efficacy and donor identity more likely showed after an invitation. Higher aggregate satisfaction and donating at fixed collection sites increased the odds of show. In addition to individual factors, collection site characteristics are important in explaining variation in donor show behaviour, thus presenting clues for blood bank policies and interventions to improve donor show. © 2017 International Society of Blood Transfusion.

Evaluation of the content and accessibility of web sites for accredited orthopaedic sports medicine fellowships.

PubMed

Mulcahey, Mary K; Gosselin, Michelle M; Fadale, Paul D

2013-06-19

The Internet is a common source of information for orthopaedic residents applying for sports medicine fellowships, with the web sites of the American Orthopaedic Society for Sports Medicine (AOSSM) and the San Francisco Match serving as central databases. We sought to evaluate the web sites for accredited orthopaedic sports medicine fellowships with regard to content and accessibility. We reviewed the existing web sites of the ninety-five accredited orthopaedic sports medicine fellowships included in the AOSSM and San Francisco Match databases from February to March 2012. A Google search was performed to determine the overall accessibility of program web sites and to supplement information obtained from the AOSSM and San Francisco Match web sites. The study sample consisted of the eighty-seven programs whose web sites connected to information about the fellowship. Each web site was evaluated for its informational value. Of the ninety-five programs, fifty-one (54%) had links listed in the AOSSM database. Three (3%) of all accredited programs had web sites that were linked directly to information about the fellowship. Eighty-eight (93%) had links listed in the San Francisco Match database; however, only five (5%) had links that connected directly to information about the fellowship. Of the eighty-seven programs analyzed in our study, all eighty-seven web sites (100%) provided a description of the program and seventy-six web sites (87%) included information about the application process. Twenty-one web sites (24%) included a list of current fellows. Fifty-six web sites (64%) described the didactic instruction, seventy (80%) described team coverage responsibilities, forty-seven (54%) included a description of cases routinely performed by fellows, forty-one (47%) described the role of the fellow in seeing patients in the office, eleven (13%) included call responsibilities, and seventeen (20%) described a rotation schedule. Two Google searches identified direct links for 67% to 71% of all accredited programs. Most accredited orthopaedic sports medicine fellowships lack easily accessible or complete web sites in the AOSSM or San Francisco Match databases. Improvement in the accessibility and quality of information on orthopaedic sports medicine fellowship web sites would facilitate the ability of applicants to obtain useful information.

A comparison between on-site immunoassay drug-testing devices and laboratory results.

PubMed

Grönholm, M; Lillsunde, P

2001-09-15

The aim with this study was to evaluate the accuracy of several on-site testing devices on the market. A part of this study is included in the European Union's (EU's) roadside testing assessment project (ROSITA). An other request for this kind of study came from the Finnish prison department in the Ministry of Justice. The evaluation was performed on both urine assays and oral fluid assays. The on-site test results were compared with laboratory results (gas chromatography-mass spectrometry (GC/MS)). The samples were tested on amphetamines (AMP), cannabinoids (THC), opiates (OPI) and cocaine metabolites (COC). Some of the tests also included a metamphetamine (MET) and a benzodiazepine (BZO) test. Both positive and negative samples were tested. A total of 800 persons and eight on-site devices for urine and two for oral fluid testing were included in this study. Good results were obtained for the urine on-site devices, with accuracies of 93-99% for amphetamines, 97-99% for cannabinoids, 94-98% for opiates and 90-98% for benzodiazepines. However, differences in the ease of performance and interpretation of test result were observed. It was possible to detect amphetamines and opiates in oral fluid by the used on-site devices, but the benzodiazepines and cannabinoids did not fulfil the needs of sensitivity.

Magnetic susceptibility data for some exposed bedrock in the western conterminous United States

USGS Publications Warehouse

Gettings, Mark E.; Bultman, Mark W.

2014-01-01

In-place rock magnetic susceptibility measurements for 746 sites in the western conterminous United States are reported in a database. Of these 746 sites, 408 sites are in the Silverton Caldera area of the San Juan Mountains of southwestern Colorado. Of the 408 sites in the Silverton Caldera area, 106 sites are underground. The remaining 338 sites outside the Silverton Caldera area were on outcropping rock, are distributed from southern Arizona to northwestern Wyoming, and include data from California, Nevada, Utah, Colorado, and New Mexico. Rock-density measurements are included for some sites. These data have been collected by various U.S. Geological Survey studies from 1991 through 2012 and are intended to help improve geophysical modeling of the Earth’s crust in the Western United States. A map-based graphical user interface is included to facilitate use of the data.

SOLVENT EXTRACTION AND SOIL WASHING TREATMENT OF CONTAMINATED SOILS FROM WOOD PRESERVING SITES: BENCH SCALE STUDIES

EPA Science Inventory

Bench-scale solvent extraction and soil washing studies were performed on soil samples obtained from three abandoned wood preserving sites that included in the NPL. The soil samples from these sites were contaminated with high levels of polyaromatic hydrocarbons (PAHs), pentachlo...

Meteorological data for four sites at surface-disruption features in Yucca Flat, Nevada Test Site, Nye County, Nevada, 1985-86

USGS Publications Warehouse

Carman, Rita L.

1994-01-01

Surface-disruption features, or craters, resulting from underground nuclear testing at the Nevada Test Site may increase the potential for ground-water recharge in an area that would normally produce little, if any, recharge. This report presents selected meteorological data resulting from a study of two surface-disruption features during May 1985 through June 1986. The data were collected at four adjacent sites in Yucca Flat, about 56 kilometers north of Mercury, Nevada. Three sites (one in each of two craters and one at an undisturbed site at the original land surface) were instrumented to collect meteorological data for calculating bare-soil evaporation. These data include (1) long-wave radiation, (2) short-wave radiation, (3) net radiation, (4) air temperae, and (5) soil surface temperature. Meteorological data also were collected at a weather station at an undisturbed site near the study craters. Data collected at this site include (1) air temperature, (2) relative humidity, (3) wind velocity, and (4) wind direction.

Compilation of selected hydrologic data, through water year 1992, Black Hills Hydrology Study, western South Dakota

USGS Publications Warehouse

Driscoll, Daniel G.; Bradford, Wendell

1994-01-01

This report presents water-level, water-quailty, and springflow data that have been collected or compiled, through water year 1992, for the Black Hills Hydrology Study. This study is a long-term cooperative effort between the U.S. Geological Survey, the South Dakota Department of Environmental and Natural Resources, and the West Dakota Water Development District (which represents various local and county cooperators). Water-level data are presented for 32 observation wells and 2 cave sites in the Black Hills area of western South Dakota. The wells are part of a network of observation wells maintained by the South Dakota Department of Environment and Natural Resources and are completed in various bedrock formations that are utilized as aquifers in the Black Hills area. Both cave sites are located within outcrops of the Madison Limestone. Data presented include site descriptions, hydrographs, and tabular data. Water- quality data are presented for 12 surface-water sites and 5 ground-water sites. Data presented include field parameters, bacteria counts, and concentrations of common ions, solids, nutrients, trace elements, radiometrics, cyanide, phenols, dissolved organic carbon, and suspended sediment. Spring data are presented for 83 springs and 21 stream reaches with significant springflow components. Data presented include site information, discharge, and field water-quality parameters including temperature, specific conductance, dissolved oxygen, and pH.

Large microplastic particles in sediments of tributaries of the River Thames, UK - Abundance, sources and methods for effective quantification.

PubMed

Horton, Alice A; Svendsen, Claus; Williams, Richard J; Spurgeon, David J; Lahive, Elma

2017-01-15

Sewage effluent input and population were chosen as predictors of microplastic presence in sediments at four sites in the River Thames basin (UK). Large microplastic particles (1mm-4mm) were extracted using a stepwise approach to include visual extraction, flotation and identification using Raman spectroscopy. Microplastics were found at all four sites. One site had significantly higher numbers of microplastics than other sites, average 66 particles 100g -1 , 91% of which were fragments. This site was downstream of a storm drain outfall receiving urban runoff; many of the fragments at this site were determined to be derived of thermoplastic road-surface marking paints. At the remaining three sites, fibres were the dominant particle type. The most common polymers identified included polypropylene, polyester and polyarylsulphone. This study describes two major new findings: presence of microplastic particles in a UK freshwater system and identification of road marking paints as a source of microplastics. This study is the first to quantify microplastics of any size in river sediments in the UK and links their presence to terrestrial sources including sewage and road marking paints. Crown Copyright © 2016. Published by Elsevier Ltd. All rights reserved.

Clinical trial allocation in multinational pharmaceutical companies - a qualitative study on influential factors.

PubMed

Dombernowsky, Tilde; Haedersdal, Merete; Lassen, Ulrik; Thomsen, Simon F

2017-06-01

Clinical trial allocation in multinational pharmaceutical companies includes country selection and site selection. With emphasis on site selection, the overall aim of this study was to examine which factors pharmaceutical companies value most when allocating clinical trials. The specific aims were (1) to identify key decision makers during country and site selection, respectively, (2) to evaluate by which parameters subsidiaries are primarily assessed by headquarters with regard to conducting clinical trials, and (3) to evaluate which site-related qualities companies value most when selecting trial sites. Eleven semistructured interviews were conducted among employees engaged in trial allocation at 11 pharmaceutical companies. The interviews were analyzed by deductive content analysis, which included coding of data to a categorization matrix containing categories of site-related qualities. The results suggest that headquarters and regional departments are key decision makers during country selection, whereas subsidiaries decide on site selection. Study participants argued that headquarters primarily value timely patient recruitment and quality of data when assessing subsidiaries. The site-related qualities most commonly emphasized during interviews were study population availability, timely patient recruitment, resources at the site, and site personnel's interest and commitment. Costs of running the trials were described as less important. Site personnel experience in conducting trials was described as valuable but not imperative. In conclusion, multinational pharmaceutical companies consider recruitment-related factors as crucial when allocating clinical trials. Quality of data and site personnel's interest and commitment are also essential, whereas costs seem less important. While valued, site personnel experience in conducting clinical trials is not imperative.

The use of UAVs to monitor archeological sites: the case study of Choirokoitia within the PROTHEGO project

NASA Astrophysics Data System (ADS)

Themistocleous, K.

2017-09-01

PROTHEGO (PROTection of European Cultural HEritage from GeO-hazards) is a collaborative research project funded in the framework of the Joint Programming Initiative on Cultural Heritage and Global Change (JPICH) - Heritage Plus in 2015-2018 (www.prothego.eu). PROTHEGO aims to make an innovative contribution towards the analysis of geo-hazards in areas of cultural heritage, and uses novel space technology for the management of sites and world heritage monuments located throughout Europe, using specialized remote sensing techniques. Τhe methodology will include the 395 monuments of UNESCO in Europe, with case studies conducted in 4 UNESCO sites in England, Spain, Italy and Cyprus. For the Cyprus case study in Choirokoitia, Unmanned Aerial Vehicles (UAVs) are used to monitor and assess the risk from natural hazards on the archaeological site to evaluate cultural heritage sites deformation. The UAVs were flown over the study area to produce time-series data, including orthoimages, 3D models and digital elevation models of the Choirokoitia site in order to identify changes in the area caused by natural hazards.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The 26-acre Shaw Avenue Dump site is a chemical waste site in Charles City, Floyd County, Iowa. Land use in the area is predominantly residential. From 1899 to 1964, Charles City used the site as a municipal landfill for waste incineration, and disposal of liming sludge from the city's publicly owned treatment works (POTW) and asphaltic materials continue to be disposed of in the landfill. Between 1977 and 1981, the State issued reports based on studies of the site and surface water that documented elevated levels of metals in an abandoned gravel pit near the site. The Record of Decisionmore » (ROD) addresses the chemical fill and surrounding contaminated soil, and the underground gasoline tank as Operable Unit 1 (OU1). A future ROD will address contaminated ground water as OU2. The primary contaminants of concern affecting the soil and debris are VOCs including benzene, toluene, and xylenes; other organics including PAHs; metals including arsenic and lead; and other inorganics. The selected remedial action for the site is included.« less

Social Networking Sites as Virtual Communities of Practice: A Mixed Method Study

ERIC Educational Resources Information Center

Davis, Lorretta J.

2010-01-01

Membership in social networking sites is increasing rapidly. Social networking sites serve many purposes including networking, communication, recruitment, and sharing knowledge. Social networking sites, public or private, may be hosted on applications such as Facebook and LinkedIn. As individuals begin to follow and participate in social…

Impact of Supplemental Site Grants to Increase African-American Accrual for SELECT

PubMed Central

Cook, Elise D.; Arnold, Kathryn B.; Hermos, John A.; McCaskill-Stevens, Worta; Moody-Thomas, Sarah; Probstfield, Jeffrey L.; Hamilton, Sandra J.; Campbell, Russell D.; Anderson, Karen B.; Minasian, Lori M.

2014-01-01

Background Low rates of minority recruitment in prevention studies may reduce the generalizability of study results to minority populations, including African Americans. High African American accrual to prevention studies requires additional resources and focused efforts. Objective To analyze the impact of Minority Recruitment Enhancement Grants (MREGs) on African American recruitment to the Selenium and Vitamin E Cancer Prevention Trial (SELECT). Results Fifteen of 427 SELECT sites received MREGs after they demonstrated early success in minority recruitment. After receiving the grants, the average monthly rate of African American recruitment at these sites increased from 27.2% to 31.5%, and total average monthly recruitment also increased. Sites that did not receive grants, including sites that did not apply, increased average monthly African American recruitment from 11.0% to 14.6% but declined in total average monthly recruitment. Conclusions and Implications Sites who received MREGs modestly increased both the proportion of African American recruits and total recruits. These results are tempered by the high cost of the intervention, the relatively low number of SELECT sites that applied for the grants and the administrative delays in implementation. Nevertheless, targeted grants may be a useful multi-site intervention to increase African American accrual for a prevention study where adequate African American recruitment is essential. PMID:20156960

Hydrologic Data from the Study of Acidic Contamination in the Miami Wash-Pinal Creek Area, Arizona, Water Years 1997-2004

USGS Publications Warehouse

Konieczki, A.D.; Brown, J.G.; Parker, J.T.C.

2008-01-01

Since 1984, hydrologic data have been collected as part of a U.S. Geological Survey study of the occurrence and movement of acidic contamination in the aquifer and streams of the Pinal Creek drainage basin near Globe, Arizona. Ground-water data from that study are presented for water years 1997 through 2004 and include location, construction information, site plans, water levels, chemical and physical field measurements, and selected chemical analyses of water samples for 31 project wells. Hydrographs of depth to ground water are also included. Surface-water data for four sites are also presented and include selected chemical analyses of water samples. Monthly precipitation data and long-term precipitation statistics are presented for two sites. Chemical analyses of samples collected from the stream and shallow ground water in the perennial reach of Pinal Creek are also included.

Identifying diabetes knowledge network nodes as sites for a diabetes prevention program.

PubMed

Gesler, Wilbert M; Arcury, Thomas A; Skelly, Anne H; Nash, Sally; Soward, April; Dougherty, Molly

2006-12-01

This paper reports on the methods used and results of a study that identified specific places within a community that have the potential to be sites for a diabetes prevention program. These sites, termed diabetes knowledge network nodes (DKNNs), are based on the concept of socio-spatial knowledge networks (SSKNs), the web of social relationships within which people obtain knowledge about type 2 diabetes. The target population for the study was working poor African Americans, Latinos, and European Americans of both sexes in a small rural southern town who had not been diagnosed with diabetes. Information was collected from a sample of 121 respondents on the places they visited in carrying out their daily activities. Data on number of visits to specific sites, degree of familiarity with these sites, and ratings of sites as places to receive diabetes information were used to develop three categories of DKNNs for six subgroups based on ethnicity and sex. Primary potential sites of importance to one or more subgroups included churches, grocery stores, drugstores, the local library, a beauty salon, laundromats, a community service agency, and a branch of the County Health Department. Secondary potential sites included gas stations, restaurants, banks, and post offices. Latent potential sites included three medical facilities. Most of the DKNNs were located either in the downtown area or in one of two shopping areas along the most used highway that passed through the town. The procedures used in this study can be generalized to other communities and prevention programs for other chronic diseases.

Effectiveness of Telementoring in Surgery Compared With On-site Mentoring: A Systematic Review.

PubMed

Bilgic, Elif; Turkdogan, Sena; Watanabe, Yusuke; Madani, Amin; Landry, Tara; Lavigne, Daniel; Feldman, Liane S; Vassiliou, Melina C

2017-08-01

Mentorship is important but may not be feasible for distance learning. To bridge this gap, telementoring has emerged. The purpose of this systematic review was to evaluate the effectiveness of telementoring compared with on-site mentoring. A search was done up to March 2015. Studies were included if they used telementoring between surgeons during a clinical encounter and if they compared on-site mentoring and telementoring. A total of 11 studies were included. All reported no difference in complication rates, and 9 (82%) reported similar operative times; 4 (36%) reported technical issues, which was 3% of the total number of cases in the 11 studies. No study reported on higher levels of evidence for effectiveness of telementoring as an educational intervention. Studies reported that telementoring is associated with similar complication rates and operative times compared with on-site mentoring. However, the level of evidence to support the effectiveness of telementoring as a training tool is limited. There is a need for studies that provide evidence for the equivalence of the effectiveness of telementoring as an educational intervention in comparison with on-site mentoring.

Baseline report - tall upland shrubland at the Rocky Flats Environmental Technology Site

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

Rocky Flats Environmental Technology Site (Site) is located on the Colorado Piedmont east of the Front Range between Boulder and Golden. At an elevation of approximately 6,000 feet, the Site contains a unique ecotonal mixture of mountain and prairie plant species, resulting from the topography and close proximity to the mountain front. The Buffer Zone surrounding the Industrial Area is one of the largest remaining undeveloped areas of its kind along the Colorado Piedmont. A number of plant communities at the Site have been identified as increasingly rare and unique by Site ecologists and the Colorado Natural Heritage Program (CNHP).more » These include the xeric tallgrass prairie, tall upland shrubland, wetlands, and Great Plains riparian woodland communities. Many of these communities support populations of increasingly rare animals as well, including the Preble`s meadow jumping mouse, grasshopper sparrow, loggerhead shrike, Merriam`s shrew, black crowned night heron, and Hops blue and Argos skipper butterflies. One of the more interesting and important plant communities at the Site is the tall upland shrubland community. It has been generally overlooked by previous Site ecological studies, probably due to its relatively small size; only 34 acres total. Although mentioned in a plant community ordination study conducted by Clark et al. and also in the Site baseline ecological study, few data were available on this plant community before the present study.« less

Future management strategies for state maintained wetlands and stream mitigation sites.

DOT National Transportation Integrated Search

2008-06-01

This study was to identify existing wetland/stream mitigation sites owned by the Kentucky Transportation Cabinet (KYTC) and assess performance of those sites including problems encountered and maintenance costs. Initial work determined that KYTC Dist...

A Feasibility Study to Evaluate Wind Energy Potential on the Navajo Nation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Terry Battiest

2012-11-30

The project, A Feasibility Study to Evaluate Wind Energy Potential on the Navajo Nation, is funded under a solicitation issued by the U.S. Department of Energy Tribal Energy Program. Funding provided by the grant allowed the Navajo Nation to measure wind potential at two sites, one located within the boundaries of the Navajo Nation and the other off-reservation during the project period (September 5, 2005 - September 30, 2009). The recipient for the grant award is the Navajo Tribal Utility Authority (NTUA). The grant allowed the Navajo Nation and NTUA manage the wind feasibility from initial site selection through themore » decision-making process to commit to a site for wind generation development. The grant activities help to develop human capacity at NTUA and help NTUA to engage in renewable energy generation activities, including not only wind but also solar and biomass. The final report also includes information about development activities regarding the sited included in the grant-funded feasibility study.« less

Water-quality assessment of part of the upper Mississippi River basin, Minnesota and Wisconsin: Design and implementation of water-quality studies, 1995-98

USGS Publications Warehouse

Stark, James R.; Fallon, J.D.; Fong, A.L.; Goldstein, R.M.; Hanson, P.E.; Kroening, S.E.; Lee, K.E.

1999-01-01

This report describes the design, site-selection, and implementation of the study. Methods used to collect, process, and analyze samples; characterize sites; and assess habitat are described. A comprehensive list of sample sites is provided. Sample analyses for water-quality studies included chlorophyll a, major inorganic constituents, nutrients, trace elements, tritium, radon, environmental isotopes, organic carbon, pesticides, volatile organic compounds, and other synthetic and naturallyoccurring organic compounds. Aquatic-biological samples included fish, benthic macroinvertebrates, and algal enumeration and identification, as well as synthetic-organic compounds and trace elements in fish tissue.

HISTORIC WETLANDS OF PRUDENCE ISLAND

EPA Science Inventory

Ten wetland sites around Narragansett Bay, Rhode Island have been selected for a multidisciplinary study. These wetland sites are being studied to develop indicators of "wetland health." The study includes assessing the ecological conditions of the wetlands in the past, and the c...

Engaging, Recruiting, and Retaining Black Men Who Have Sex With Men in Research Studies: Don’t Underestimate the Importance of Staffing—Lessons Learned From HPTN 061, the BROTHERS Study

PubMed Central

Magnus, Manya; Franks, Julie; Griffith, Sam; Arnold, Michael P.; Goodman, Krista; Wheeler, Darrell P.

2014-01-01

Context HIV/AIDS in the United States continues to primarily impact men who have sex with men (MSM), with disproportionately high rates among black MSM. Objective The purpose of this study was to identify factors that may influence engagement and retention of black MSM in HIV research. Design and Participants This was a qualitative evaluation of study implementation within a multisite, prospective, observational study (HIV Prevention Trials Network 061, BROTHERS) that enrolled 1553 black MSM in 6 cities throughout the United States. Data collection for this evaluation included a written, structured survey collected from each of the sites describing site characteristics including staff and organizational structure, reviews of site standard operating procedures, and work plans; semistructured key informant interviews were conducted with site coordinators to characterize staffing, site-level factors facilitating or impeding effective community engagement, study recruitment, and retention. Data from completed surveys and site standard operating procedures were collated, and notes from key informant interviews were thematically coded for content by 2 independent reviewers. Results Several key themes emerged from the data, including the importance of inclusion of members of the community being studied as staff, institutional hiring practices that support inclusive staffing, cultivating a supportive working environment for study implementation, and ongoing relationships between research institutions and community. Conclusions This study underscores the importance of staffing in implementing research with black MSM. Investigators should consider how staffing and organizational structures affect implementation during study design and when preparing to initiate study activities. Ongoing monitoring of community engagement can inform and improve methods for engagement and ensure cultural relevance while removing barriers for participation. PMID:24406940

Engaging, recruiting, and retaining black men who have sex with men in research studies: don't underestimate the importance of staffing--lessons learned from HPTN 061, the BROTHERS study.

PubMed

Magnus, Manya; Franks, Julie; Griffith, Sam; Arnold, Michael P; Goodman, Krista; Wheeler, Darrell P

2014-01-01

HIV/AIDS in the United States continues to primarily impact men who have sex with men (MSM), with disproportionately high rates among black MSM. The purpose of this study was to identify factors that may influence engagement and retention of black MSM in HIV research. This was a qualitative evaluation of study implementation within a multisite, prospective, observational study (HIV Prevention Trials Network 061, BROTHERS) that enrolled 1553 black MSM in 6 cities throughout the United States. Data collection for this evaluation included a written, structured survey collected from each of the sites describing site characteristics including staff and organizational structure, reviews of site standard operating procedures, and work plans; semistructured key informant interviews were conducted with site coordinators to characterize staffing, site-level factors facilitating or impeding effective community engagement, study recruitment, and retention. Data from completed surveys and site standard operating procedures were collated, and notes from key informant interviews were thematically coded for content by 2 independent reviewers. Several key themes emerged from the data, including the importance of inclusion of members of the community being studied as staff, institutional hiring practices that support inclusive staffing, cultivating a supportive working environment for study implementation, and ongoing relationships between research institutions and community. This study underscores the importance of staffing in implementing research with black MSM. Investigators should consider how staffing and organizational structures affect implementation during study design and when preparing to initiate study activities. Ongoing monitoring of community engagement can inform and improve methods for engagement and ensure cultural relevance while removing barriers for participation.

Seismic Wave Amplification in Las Vegas: Site Characterization Measurements and Response Models

NASA Astrophysics Data System (ADS)

Louie, J. N.; Anderson, J. G.; Luke, B.; Snelson, C.; Taylor, W.; Rodgers, A.; McCallen, D.; Tkalcic, H.; Wagoner, J.

2004-12-01

As part of a multidisciplinary effort to understand seismic wave amplification in Las Vegas Valley, we conducted geotechnical and seismic refraction field studies, geologic and lithologic interpretation, and geophysical model building. Frequency-dependent amplifications (site response) and peak ground motions strongly correlate with site conditions as characterized by the models. The models include basin depths and velocities, which also correlate against ground motions. Preliminary geologic models were constructed from detailed geologic and fault mapping, logs of over 500 wells penetrating greater than 200 m depth, gravity-inversion results from the USGS, and USDA soil maps. Valley-wide refraction studies we conducted in 2002 and 2003 were inverted for constraints on basin geometry, and deep basin and basement P velocities with some 3-d control to depths of 5 km. Surface-wave studies during 2002-2004 characterized more than 75 sites within the Valley for shear velocity to depths exceeding 100 m, including all the legacy sites where nuclear-blast ground motions were recorded. The SASW and refraction-microtremor surface-surveying techniques proved to provide complementary, and coordinating Rayleigh dispersion-curve data at a dozen sites. Borehole geotechnical studies at a half-dozen sites confirmed the shear-velocity profiles that we derived from surface-wave studies. We then correlated all the geotechnical data against a detailed stratigraphic model, derived from drilling logs, to create a Valley-wide model for shallow site conditions. This well-log-based model predicts site measurements better than do models based solely on geologic or soil mapping.

Connecting with health science students and faculty to facilitate the design of a mobile library website.

PubMed

Grabowsky, Adelia; Wright, Melissa

2013-01-01

Observing increasing usage of smartphones by students and faculty of the University of Mississippi Medical Center, librarians at Rowland Medical Library decided to explore student and faculty interest in a mobile website for the library. Focus groups were held to examine interest in a site, essential resources to include on a site, and format of the site itself. The study found significant interest in the development of a mobile library website; additionally, participants believed it essential that the site be simple and easy to use and that only certain library resources should be included on the site.

Evaluation of breastfeeding Web sites for patient education.

PubMed

Dornan, Barbara A; Oermann, Marilyn H

2006-01-01

To evaluate the quality of Web sites on breastfeeding for patient education. Descriptive study of 30 Web sites on breastfeeding for patient education, evaluated based on the Health Information Technology Institute (HITI) criteria, readability, and eight content criteria from the American Academy of Pediatrics (AAP) policy statement on breastfeeding. The mean Flesch-Kincaid Grade Level for readability of the 30 sites was 9.2. Seven of the sites included all eight of the content criteria from the AAP, and three sites did not include any of the information recommended by the AAP content criteria. Nurses should be able to recommend best patient education materials for their patients. The five best Web sites for breastfeeding education are identified for patient teaching, and the HITI criteria are explained for nurses to learn how to evaluate Web sites for themselves and their patients.

SHRP2 naturalistic driving study, phase I summary : State College, Pennsylvania data collection site.

DOT National Transportation Integrated Search

2013-08-01

The Strategic Highway Research Program 2 (SHRP2) Naturalistic Driving Study is the largest naturalistic driving study undertaken, collecting data from six sites around the United States, including State College, PA. Recruitment and admission of human...

Reading level of privacy policies on Internet health Web sites.

PubMed

Graber, Mark A; D'Alessandro, Donna M; Johnson-West, Jill

2002-07-01

Most individuals would like to maintain the privacy of their medical information on the World Wide Web (WWW). In response, commercial interests and other sites post privacy policies that are designed to inform users of how their information will be used. However, it is not known if these statements are comprehensible to most WWW users. The purpose of this study was to determine the reading level of privacy statements on Internet health Web sites and to determine whether these statements can inform users of their rights. This was a descriptive study. Eighty Internet health sites were examined and the readability of their privacy policies was determined. The selected sample included the top 25 Internet health sites as well as other sites that a user might encounter while researching a common problem such as high blood pressure. Sixty percent of the sites were commercial (.com), 17.5% were organizations (.org), 8.8% were from the United Kingdom (.uk), 3.8% were United States governmental (.gov), and 2.5% were educational (.edu). The readability level of the privacy policies was calculated using the Flesch, the Fry, and the SMOG readability levels. Of the 80 Internet health Web sites studied, 30% (including 23% of the commercial Web sites) had no privacy policy posted. The average readability level of the remaining sites required 2 years of college level education to comprehend, and no Web site had a privacy policy that was comprehensible by most English-speaking individuals in the United States. The privacy policies of health Web sites are not easily understood by most individuals in the United States and do not serve to inform users of their rights. Possible remedies include rewriting policies to make them comprehensible and protecting online health information by using legal statutes or standardized insignias indicating compliance with a set of privacy standards (eg, "Health on the Net" [HON] http://www.hon.ch).

A Generational Change in Site Index for Naturally Established Longleaf Pine on a South Alabama Coastal Plain Site

Treesearch

William D. Boyer

2001-01-01

Research on longleaf pine (Pinus palustris Mill.) has been carried out for over 50 yr on a coastal plain site in south Alabama. Studies havie included the original second-growth stands and also naturally established third-growth stands. Site index data revealed that estimated site index values for third growth generally exceeded those for second...

A generational change in site index for naturally established longleaf pine on a south Alabama Coastal Plain site

Treesearch

William D. Boyer

2001-01-01

Research on longleaf pine (Pinus palustris Mill.) has been carried out for over 50 yr on a Coastal Plain site in south Alabama. Studies have included the original second-growth stands and also naturally established third-growth stands. Site index data revealed that estimated site index values for third growth generally exceeded those for second...

Superfund record of decision (EPA Region 5): Skinner Landfill, Butler County, Union Township, West Chester, OH. (First remedial action), September 1992. Interim report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-09-30

The 78-acre Skinner Landfill site is located in West Chester, Butler County, Ohio. Land use in the immediate vicinity includes business and residential uses to the west and crop farming to the north. The site was used in the past for the mining of sand and gravel, and was operated for the landfilling of a wide variety of materials from approximately 1934 through 1990. Materials deposited onsite include demolition debris, household refuse, and a wide variety of chemical wastes. In 1982, EPA conducted an investigation that showed that the groundwater southeast of the buried waste lagoon was contaminated with VOCs.more » RI studies conducted between 1986 and 1989 investigated the site ground water, surface water, soil, and sediment. In 1990, the state closed the site to further landfilling activities. The ROD is an interim action to protect human health by limiting site access to prevent ingestion of and direct contact with contaminated soil, and to protect the potentially affected users of ground water on and near the site. The primary contaminants of concern affecting the soil and ground water are VOCs, including benzene; organics, including PAHs, PCBs, and pesticides; and metals, including arsenic. The selected interim remedial action for the site are included.« less

Superfund Site Information

EPA Pesticide Factsheets

This asset includes a number of individual data sets related to site-specific information for Superfund, which is governed under the Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) of 1980, which was amended by the Superfund Amendments and Reauthorization Act (SARA) in 1986. The Superfund Enterprise Management System (SEMS) contains basic site description, location, schedule of activities, enforcement and settlement data, contaminants and selected remedy and much more, as well as the records that clearly document site decisions. This asset also includes sampling data and lab results (CLPSS, EDDs), redevelopment and technical assistance case studies, site reuse and land revitalization information, EPAOSC.net information, Superfund Technical Assistance Grants information, site management information records (RODs, Remediation plans, cleanup directives), contract management information, and more.Superfund site management information can also be found in agency wide systems such as EAS and COMPASS.

Haemostatic effects of adrenaline-lidocaine subcutaneous infiltration at donor sites.

PubMed

Gacto, P; Miralles, F; Pereyra, J J; Perez, A; Martínez, E

2009-05-01

This study sought methods in burn surgery to reduce postoperative pain and blood loss at donor sites. A prospective, randomised, controlled, blinded trial included 56 people undergoing burn surgery, divided into two groups. Both groups received subcutaneous infiltration at donor sites, with either 1:500,000 adrenaline solution containing added lidocaine or with 0.45% normal saline (controls). Outcome measurements included amount of intraoperative bleeding, need for electrocautery, days the hydrocolloid dressing remained on donor sites, percentage of re-epithelialised skin at donor sites 1 week after surgery and viability of skin grafts. Results indicated that subcutaneous adrenaline-lidocaine infiltration at donor sites reduced intraoperative bleeding, decreased postoperative pain, shortened the duration of surgery and general anaesthesia and accelerated re-epithelialisation at the donor site. The overall graft take in both groups was similar.

Effects of common seagrass restoration methods on ecosystem structure in subtropical seagrass meadows.

PubMed

Bourque, Amanda S; Fourqurean, James W

2014-06-01

Seagrass meadows near population centers are subject to frequent disturbance from vessel groundings. Common seagrass restoration methods include filling excavations and applying fertilizer to encourage seagrass recruitment. We sampled macrophytes, soil structure, and macroinvertebrate infauna at unrestored and recently restored vessel grounding disturbances to evaluate the effects of these restoration methods on seagrass ecosystem structure. After a year of observations comparing filled sites to both undisturbed reference and unrestored disturbed sites, filled sites had low organic matter content, nutrient pools, and primary producer abundance. Adding a nutrient source increased porewater nutrient pools at disturbed sites and in undisturbed meadows, but not at filled sites. Environmental predictors of infaunal community structure across treatments included soil texture and nutrient pools. At the one year time scale, the restoration methods studied did not result in convergence between restored and unrestored sites. Particularly in filled sites, soil conditions may combine to constrain rapid development of the seagrass community and associated infauna. Our study is important for understanding early recovery trajectories following restoration using these methods. Published by Elsevier Ltd.

Recruiting Human Microbiome Shotgun Data to Site-Specific Reference Genomes

PubMed Central

Xie, Gary; Lo, Chien-Chi; Scholz, Matthew; Chain, Patrick S. G.

2014-01-01

The human body consists of innumerable multifaceted environments that predispose colonization by a number of distinct microbial communities, which play fundamental roles in human health and disease. In addition to community surveys and shotgun metagenomes that seek to explore the composition and diversity of these microbiomes, there are significant efforts to sequence reference microbial genomes from many body sites of healthy adults. To illustrate the utility of reference genomes when studying more complex metagenomes, we present a reference-based analysis of sequence reads generated from 55 shotgun metagenomes, selected from 5 major body sites, including 16 sub-sites. Interestingly, between 13% and 92% (62.3% average) of these shotgun reads were aligned to a then-complete list of 2780 reference genomes, including 1583 references for the human microbiome. However, no reference genome was universally found in all body sites. For any given metagenome, the body site-specific reference genomes, derived from the same body site as the sample, accounted for an average of 58.8% of the mapped reads. While different body sites did differ in abundant genera, proximal or symmetrical body sites were found to be most similar to one another. The extent of variation observed, both between individuals sampled within the same microenvironment, or at the same site within the same individual over time, calls into question comparative studies across individuals even if sampled at the same body site. This study illustrates the high utility of reference genomes and the need for further site-specific reference microbial genome sequencing, even within the already well-sampled human microbiome. PMID:24454771

Variability of the institutional review board process within a national research network.

PubMed

Khan, Muhammad A; Barratt, Michelle S; Krugman, Scott D; Serwint, Janet R; Dumont-Driscoll, Marilyn

2014-06-01

To determine the variability of the institutional review board (IRB) process for a minimal risk multicenter study. Participants included 24 Continuity Research Network (CORNET) sites of the Academic Pediatric Association that participated in a cross-sectional study. Each site obtained individual institutional IRB approval. An anonymous questionnaire went to site investigators about the IRB process at their institution. Twenty-two of 24 sites (92%) responded. Preparation time ranged from 1 to 20 hours, mean of 7.1 hours. Individuals submitting ≤3 IRB applications/year required more time for completion than those submitting >3/year (P < .05). Thirteen of 22 (59%) study sites received approval with "exempt" status, and 6 (27%) approved as "expedited" studies. IRB experiences were highly variable across study sites. These findings indicate that multicenter research projects should anticipate barriers to timely study implementation. Improved IRB standardization or centralization for multicenter clinical studies would facilitate this type of practice-based clinical research.

Human health exposure assessment for Rocky Mountain Arsenal study area evaluations. Volume 6-E. Central study area exposure assessment. Version 4. 1(volume 6-E). Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The objectives of the Human Health Exposure Assessment include: (1) estimate the type and magnitude of exposures to contaminants; (2) Identify contaminants of concern; (3) Identify sites for remedial action; (4) Recommend sites for the no action remedial alternative; and (5) Provide a basis for detailed characterization of the risk associated with all sites. This document consists of the following: An executive summary. Vol I - Land use and exposed population evaluations. Vol. II III - Toxicity assessment (includes army and shell toxicity profiles). Vol. IV - PPLV Methodology. Vol. V - PPLV Calculations. Vol. VI - Study area exposuremore » analysis A introduction, B Western study ares, C Southern study area, D northern Central study area, E Central study area, F Eastern study area, G South plants study area, and H North plants study area. Vol. VII - Summary exposure assessment.« less

Study area evaluations. Volume 6-H. North plants study area exposure assessment version 4. 1. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The objectives of the Human Health Exposure Assessment include: (1) estimate the type and magnitude of exposures to contaminants; (2) Identify contaminants of concern; (3) Identify sites for remedial action; (4) Recommend sites for the no action remedial alternative; and (5) Provide a basis for detailed characterization of the risk associated with all sites. This document consists of the following: An executive summary. Vol I - Land use and exposed population evaluations. Vol. II III - Toxicity assessment (includes army and shell toxicity profiles). Vol. IV - PPLV Methodology. Vol. V - PPLV Calculations. Vol. VI - Study area exposuremore » analysis A introduction, B Western study ares, C Southern study area, D northern Central study area, E Central study area, F Eastern study area, G South plants study area, and H North plants study area. Vol. VII - Summary exposure assessment.« less

Human health exposure assessment for Rocky Mountain Arsenal study area evaluations. Volume 6-F. Eastern study area exposure assessment. Version 4. 1(volume 6-F). Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The objectives of the Human Health Exposure Assessment include: (1) estimate the type and magnitude of exposures to contaminants; (2) Identify contaminants of concern; (3) Identify sites for remedial action; (4) Recommend sites for the no action remedial alternative; and (5) Provide a basis for detailed characterization of the risk associated with all sites. This document consists of the following: An executive summary. Vol I - Land use and exposed population evaluations. Vol. II III - Toxicity assessment (includes army and shell toxicity profiles). Vol. IV - PPLV Methodology. Vol. V - PPLV Calculations. Vol. VI - Study area exposuremore » analysis A introduction, B Western study ares, C Southern study area, D northern Central study area, E Central study area, F Eastern study area, G South plants study area, and H North plants study area. Vol. VII - Summary exposure assessment.« less

Human health exposure assessment for Rocky Mountain Arsenal study area evaluations. Volume 6-C. Southern study area exposure assessment version 4. 1. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The objectives of the Human Health Exposure Assessment include: (1) estimate the type and magnitude of exposures to contaminants; (2) Identify contaminants of concern; (3) Identify sites for remedial action; (4) Recommend sites for the no action remedial alternative; and (5) Provide a basis for detailed characterization of the risk associated with all sites. This document consists of the following: An executive summary. Vol I - Land use and exposed population evaluations. Vol. II III - Toxicity assessment (includes army and shell toxicity profiles). Vol. IV - PPLV Methodology. Vol. V - PPLV Calculations. Vol. VI - Study area exposuremore » analysis A introduction, B Western study ares, C Southern study area, D northern Central study area, E Central study area, F Eastern study area, G South plants study area, and H North plants study area. Vol. VII - Summary exposure assessment.« less

Environmental sciences information storage and retrieval system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Engstrom, D.E.; White, M.G.; Dunaway, P.B.

Reynolds Electrical and Engineering Co., Inc. (REECo), has since 1970 accumulated information relating to the AEC's Nevada Applied Ecology Group (NAEG) programs at the Nevada Test Site (NTS). These programs, involving extensive soil, vegetation, and small-animal studies, have generated informational data concerning the collecting, processing, analyzing, and shipping of sample materials to various program participants and contractors. Future plans include incorporation of Lawrence Livermore Laboratory's resuspension study data, REECo's on-site air data, and EPA's large-animal, off-site air, and off-site soil data. (auth)

Feasibility of growing olives on selected sites along coastal Texas

USDA-ARS?s Scientific Manuscript database

Five sites along the Texas coastline (Seadrift, Galveston, Brazoria, Santa Fe, and Orange) were evaluated for feasibility of growing olives in these areas. In addition, two non-coastal sites (Carrizo Springs and Weslaco) were also included in the study for comparative purposes. Flowering and fruit ...

Federated Search and the Library Web Site: A Study of Association of Research Libraries Member Web Sites

ERIC Educational Resources Information Center

Williams, Sarah C.

2010-01-01

The purpose of this study was to investigate how federated search engines are incorporated into the Web sites of libraries in the Association of Research Libraries. In 2009, information was gathered for each library in the Association of Research Libraries with a federated search engine. This included the name of the federated search service and…

75 FR 65355 - Agency Forms Undergoing Paperwork Reduction Act Review

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-22

... Project Case Studies of Communities and States Funded under Community Activities under the Communities..., system, and environmental changes. Intensive case studies will be conducted with 24 sites: Six ARRA... Act. The case study sites will be selected to include a mix of State or community characteristics...

Strategies to achieve long-term benefits from multiple operational herbicide applications in lower coastal plain pine stands

Treesearch

Harold E. Quicke; Dwight K. Lauer

2010-01-01

Studies were installed on a range of soils to examine different post-plant herbaceous weed control timings following different site preparation timings with Chopper® herbicide. Chopper site preparation treatments were applied after bedding and included two application dates (August versus November). Pines were planted in winter following site preparation. Site...

Tunnel-Site Selection by Remote Sensing Techniques

DTIC Science & Technology

A study of the role of remote sensing for geologic reconnaissance for tunnel-site selection was commenced. For this study, remote sensing was defined...conventional remote sensing . Future research directions are suggested, and the extension of remote sensing to include airborne passive microwave

Vegetation analysis for arid lands geobotany

NASA Technical Reports Server (NTRS)

Barbour, M. G.; Ustin, S. L.

1985-01-01

Three primary study sites were selected for measurement of plant phenological properties and spectral analysis. The sites selected represented typical sagebrush, creosote bush, and saltbush communities in Owens Valley, CA. Community composition was studied at these three sites plus five burned sites. Ten 50 m transects at each locality were measured for percent cover (over 10 cm) by a given species. On each transect two point quarter and five nearest neighbor analyses were conducted. These data provided percent cover, cover by area, plant size, tendency for association, and recolonization patterns after a disturbance. Plots representing percentage plant cover for six sites are included.

Human health exposure assessment for Rocky Mountain Arsenal. Volume 7. Summary exposure assessment version 4. 1. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The objectives of the Human Health Exposure Assessment include: (1) estimate the type and magnitude of exposures to contaminants; (2) Identify contaminants of concern; (3) Identify sites for remedial action; (4) Recommend sites for the no action remedial alternative; and (5) Provide a basis for detailed characterization of the risk associated with all sites. This document consists of the following: An executive summary. Vol I - Land use and exposed population evaluations. Vol. II III - Toxicity assessment (includes army and shell toxicity profiles). Vol. IV - PPLV Methodology. Vol. V - PPLV Calculations. Vol. VI - Study area exposuremore » analysis A introduction, B Western study ares, C Southern study area, D northern Central study area, E Central study area, F Eastern study area, G South plants study area, and H North plants study area. Vol. VII - Summary exposure assessment.« less

Human health exposure assessment for Rocky Mountain Arsenal. Volume 8. Response to comments on the draft exposure assessment version 4. 1. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The objectives of the Human Health Exposure Assessment include: (1) estimate the type and magnitude of exposures to contaminants; (2) Identify contaminants of concern; (3) Identify sites for remedial action; (4) Recommend sites for the no action remedial alternative; and (5) Provide a basis for detailed characterization of the risk associated with all sites. This document consists of the following: An executive summary. Vol I - Land use and exposed population evaluations. Vol. II III - Toxicity assessment (includes army and shell toxicity profiles). Vol. IV - PPLV Methodology. Vol. V - PPLV Calculations. Vol. VI - Study area exposuremore » analysis A introduction, B Western study ares, C Southern study area, D northern Central study area, E Central study area, F Eastern study area, G South plants study area, and H North plants study area. Vol. VII - Summary exposure assessment.« less

Human health exposure assessment for Rocky Mountain Arsenal. Volume 2-A. Toxicity assessment. Version 4. 1. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The objectives of the Human Health Exposure Assessment include: (1) estimate the type and magnitude of exposures to contaminants; (2) Identify contaminants of concern; (3) Identify sites for remedial action; (4) Recommend sites for the no action remedial alternative; and (5) Provide a basis for detailed characterization of the risk associated with all sites. This document consists of the following: An executive summary. Vol I - Land use and exposed population evaluations. Vol. II III - Toxicity assessment (includes army and shell toxicity profiles). Vol. IV - PPLV Methodology. Vol. V - PPLV Calculations. Vol. VI - Study area exposuremore » analysis a introduction, B Western study ares, C Southern study area, D northern Central study area, E Central study area, F Eastern study area, G South plants study area, and H North plants study area. Vol. VII - Summary exposure assessment.« less

Human health exposure assessment for Rocky Mountain Arsenal. Volume 3. Toxicity assessment version 4. 1. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The objectives of the Human Health Exposure Assessment include: (1) estimate the type and magnitude of exposures to contaminants; (2) Identify contaminants of concern; (3) Identify sites for remedial action; (4) Recommend sites for the no action remedial alternative; and (5) Provide a basis for detailed characterization of the risk associated with all sites. This document consists of the following: An executive summary. Vol I - Land use and exposed population evaluations. Vol. II III - Toxicity assessment (includes army and shell toxicity profiles). Vol. IV - PPLV Methodology. Vol. V - PPLV Calculations. Vol. VI - Study area exposuremore » analysis A introduction, B Western study ares, C Southern study area, D northern Central study area, E Central study area, F Eastern study area, G South plants study area, and H North plants study area. Vol. VII - Summary exposure assessment.« less

Human health exposure assessment for Rocky Mountain Arsenal. Volume 1. Land use and exposed population evaluations version 4. 1. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The objectives of the Human Health Exposure Assessment include: (1) estimate the type and magnitude of exposures to contaminants; (2) Identify contaminants of concern; (3) Identify sites for remedial action; (4) Recommend sites for the no action remedial alternative; and (5) Provide a basis for detailed characterization of the risk associated with all sites. This document consists of the following: An executive summary. Vol I - Land use and exposed population evaluations. Vol. II III - Toxicity assessment (includes army and shell toxicity profiles). Vol. IV - PPLV Methodology. Vol. V - PPLV Calculations. Vol. VI - Study area exposuremore » analysis A introduction, B Western study ares, C Southern study area, D northern Central study area, E Central study area, F Eastern study area, G South plants study area, and H North plants study area. Vol. VII - Summary exposure assessment.« less

Ecology of the Nevada Test Site. I. Geographic and ecologic distributions of the vascular flora (annotated checklist)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Beatley, J C

1965-04-01

A checklist of vascular plants of the Nevada Test Site is presented for use in studies of plant ecology. Data on the occurrence and distribution of plant species are included. Collections were made from both undisturbed and disturbed sites.

SITE CHARACTERIZATION AND THERMAL REMEDIATION TREATABILITY STUDIES FOR TWO WOOD TREATER SITES

EPA Science Inventory

Assessment of the applicability of thermal remediation at two wood treater sites is ongoing. The two wood treaters had been in operation for 50 to 80 years, and a variety of wood treating chemicals had been employed, including creosote, pentachlorophenol, and various metal prepa...

THE OHIO RIVER BASIN ENERGY FACILITY SITING MODEL. VOLUME II: SITES AND ON-LINE DATES

EPA Science Inventory

The report was prepared as part of the Ohio River Basin Energy Study (ORBES), a multidisciplinary policy research program. The siting model developed for ORBES is specifically designed for regional policy analysis. The region includes 423 counties in an area that consists of all ...

Investigation of suitability of ventrogluteal site for intramuscular injections in children aged 36 months and under.

PubMed

Atay, Selma; Yilmaz Kurt, Fatma; Akkaya, Gülnur; Karatağ, Gülden; Ilhan Demir, Şeyda; Çalidağ, Ulviye

2017-10-01

This study was performed to determine suitability of ventrogluteal (VG) site for intramuscular (IM) injections in children aged 36 months and under. The present study was designed as a prospective descriptive study and performed between 2016 January and June. The study included a total of 120 children aged 36 months and under that met the study criteria. The subcutaneous tissue thickness and muscle thickness of anterolateral, deltoid, and VG sites were measured and assessed by ultrasound. A strong and powerful correlation was identified between the measurements of subcutaneous tissue and muscle thicknesses in the injection site by the age groups. The thickness of subcutaneous tissue was deltoid < anterolateral < VG by age groups. The muscle thickness of anterolateral and VG sites was significantly higher than that of deltoid site. This study established that skin thickness of VG site was suitable for IM injection in children aged 36 months and under. © 2017 Wiley Periodicals, Inc.

Topic I: Induced changes in hydrology at low-level radioactive waste repository sites: A section in Safe disposal of radionuclides in low-level radioactive-waste repository sites; Low-level radioactive-waste disposal workshop, U.S. Geological Survey, July 11-16, 1987, Big Bear Lake, Calif., Proceedings (Circular 1036)

USGS Publications Warehouse

Prudic, David E.; Dennehy, Kevin F.; Bedinger, Marion S.; Stevens, Peter R.

1990-01-01

Engineering practices, including the excavation of trenches, placement of waste, nature of waste forms, backfilling procedures and materials, and trench-cover construction and materials at low-level radioactive-waste repository sites greatly affect the geohydrology of the sites. Engineering practices are dominant factors in eventual stability and isolation of the waste. The papers presented relating to Topic I were discussions of the hydrogeologic setting at existing low-level radioactive-waste repository sites and changes in the hydrology induced by site operations. Papers summarizing detailed studies presented at this workshop include those at sites near Sheffield, Ill.; Oak Ridge National Laboratory, Tenn.; West Valley, N.Y.; Maxey Flats, Ky.; Barnwell, S.C.; and Beatty, Nev. 

The National Children's Study: Recruitment Outcomes Using an Enhanced Household-Based Approach.

PubMed

Blaisdell, Laura L; Zellner, Jennifer A; King, Alison A; Faustman, Elaine; Wilhelm, Mari; Hudak, Mark L; Annett, Robert D

2016-06-01

Ten National Children's Study (NCS) study locations with diverse demographic characteristics used an enhanced household-based recruitment (EHBR) approach to enroll preconceptional and pregnant women. Study centers used different types and dosages of community outreach and engagement (COE) activities and supplemental strategies. The goal of the study was to determine whether variability in enumeration and recruitment outcomes correlated with study location characteristics or types and dosages of COE activities (number of COE events, number of advance household mailings, total media expenditures, and total COE expenditures). Each of the sites provided data on COE activities, protocol implementation, supplemental recruitment activities, location demographic characteristics, and enumeration/recruitment outcomes. COE activities varied across sites in breadth and scope. Numerous strategies were used, including media advertising, social media, participation in community-wide events, presentations to stakeholders, and creation of advisory boards. Some sites included supplemental recruitment efforts. EHBR sites enrolled 1404 women at the initial pregnancy screening. No significant relationships were found between study location demographic characteristics or between the types and dosages of COE activities and recruitment outcomes. Probability sampling for a long-term study requires a positive image with stakeholders and within communities; this requirement may be especially true for door-to-door recruitment. EHBR sites successfully recruited a representative sample of preconceptional and pregnant women. Sites reported implementing similar COE activities but with varying dosage and cost; however, analyses did not support a benefit of COE strategies on study recruitment. Copyright © 2016 by the American Academy of Pediatrics.

On-Site Pedagogical Content Knowledge Development

NASA Astrophysics Data System (ADS)

Chan, Kennedy Kam Ho; Yung, Benny Hin Wai

2015-05-01

Experiences and reflection have long been regarded as a foundation for pedagogical content knowledge (PCK) development. However, little is known about how experienced teachers develop their PCK via reflection-in-action during their moment-to-moment classroom instruction. Drawing upon data sources including classroom observations, semi-structured interviews and stimulated recall interviews based on lesson videos, this study examined instances when four experienced teachers were found to invent new instructional strategies/representations on the spot during the lesson (referred to as on-site PCK development) in their first attempts at teaching a new topic. The study documented the moment-to-moment experiences of the teachers, including their reconstructed thought processes associated with these instances of on-site PCK development. An explanatory model of a three-step process comprising a stimulus, an integration process and a response was advanced to account for the on-site PCK development observed among the teachers. Three categories of stimulus that triggered on-site PCK development were identified. Factors influencing the integration process and, hence, the resulting response, included teachers' subject matter knowledge of the new topic, their general pedagogical knowledge and their knowledge of student learning difficulties/prior knowledge related to the new topic. Implications for teacher professional development in terms of how to enhance teachers' on-site PCK development are discussed.

Selected hydrologic data, through water year 1994, Black Hills Hydrology Study, South Dakota

USGS Publications Warehouse

Driscoll, D.G.; Bradford, W.L.; Neitzert, K.M.

1996-01-01

This report presents water-level, water-quality, and spring data that have been collected or compiled, through water year 1994, for the Black Hills Hydrology Study. This study is a long-term cooperative effort between the U.S. Geological Survey, the South Dakota Department of Environment and Natural Resources, and the West Dakota Water Development District (which represents various local and county cooperators). This report is the second in a series of biennial project data reports produced for the study. Daily water-level data are presented for 39 observation wells and 2 cave sites in the Black Hills area of western South Dakota. The wells are part of a network of observation wells maintained by the Department of Environment and Natural Resources and are completed in various bedrock formations that are utilized as aquifers in the Black Hills area. Both cave sites are located within outcrops of the Madison Limestone. Data presented include site descriptions, hydrographs, and tables of daily water levels. Annual measurements of water levels collected during water years 1993-94 from a network of 20 additional, miscellaneous wells are presented. These wells are part of a Statewide network of wells completed in bedrock aquifers that was operated from 1959 through 1989 in cooperation with the Department of Environment and Natural Resources. Site descriptions and hydrographs for the entire period of record for each site also are presented. Drawdown and recovery data are presented for five wells that were pumped (or flowed) for collection of water-quality samples. These wells are part of the network of observation wells for which daily water-level records are compiled. Water-quality data are presented for 20 surface-water sites and 22 ground-water sites. Data presented include field parameters, bacteria counts, and concentrations of common ions, solids, nutrients, trace elements, radiometrics and isotopes, cyanide, phenols, and suspended sediment. Spring data are presented for 94 springs and 21 stream reaches with significant springflow components. Data presented include site information, discharge, and field water-quality parameters including temperature, specific conductance, dissolved oxygen, and pH.

Assessing the feasibility of the Effectiveness of Discontinuing Bisphosphonates trial: a pilot study.

PubMed

Wright, N C; Foster, P J; Mudano, A S; Melnick, J A; Lewiecki, M E; Shergy, W J; Curtis, J R; Cutter, G R; Danila, M I; Kilgore, M L; Lewis, E C; Morgan, S L; Redden, D T; Warriner, A H; Saag, K G

2017-08-01

The Effectiveness of Discontinuing Bisphosphonates (EDGE) study is a planned pragmatic clinical trial to guide "drug holiday" clinical decision making. This pilot study assessed work flow and feasibility of such a study. While participant recruitment and treatment adherence were suboptimal, administrative procedures were generally feasible and minimally disrupted clinic flow. The comparative effectiveness of continuing or discontinuing long-term alendronate (ALN) on fractures is unknown. A large pragmatic ALN discontinuation study has potential to answer this question. We conducted a 6-month pilot study of the planned the EDGE study among current long-term ALN users (women aged ≥65 with ≥3 years of ALN use) to determine study work flow and feasibility including evaluating the administrative aspects of trial conduct (e.g., time to contract, institutional review board (IRB) approval), assessing rates of site and participant recruitment, and evaluating post-randomization outcomes, including adherence, bisphosphonate-associated adverse events, and participant and site satisfaction. We assessed outcomes 1 and 6 months after randomization. Nine sites participated, including seven community-based medical practices and two academic medical centers. On average (SD), contract execution took 3.4 (2.3) months and IRB approval took 13.9 (4.1) days. Sites recruited 27 participants (13 to continue ALN and 14 to discontinue ALN). Over follow-up, 22% of participants did not adhere to their randomization assignment: 30.8% in the continuation arm and 14.3% in the discontinuation arm. No fractures or adverse events were reported. Sites reported no issues regarding work flow, and participants were highly satisfied with the study. Administrative procedures of the EDGE study were generally feasible, with minimal disruption to clinic flow. In this convenience sample, participant recruitment was suboptimal across most practice sites. Accounting for low treatment arm adherence, a comprehensive recruitment approach will be needed to effectively achieve the scientific goals of the EDGE study.

Analogue Study of Actinide Transport at Sites in Russia

DOE Office of Scientific and Technical Information (OSTI.GOV)

Novikov, A P; Simmons, A M; Halsey, W G

2003-02-12

The U. S. Department of Energy (DOE) and the Russian Academy of Sciences (RAS) are engaged in a three-year cooperative study to observe the behavior of actinides in the natural environment at selected disposal sites and/or contamination sites in Russia. The purpose is to develop experimental data and models for actinide speciation, mobilization and transport processes in support of geologic repository design, safety and performance analyses. Currently at the mid-point of the study, the accomplishments to date include: evaluation of existing data and data needs, site screening and selection, initial data acquisition, and development of preliminary conceptual models.

Readability of menopause web sites: a cross-sectional study.

PubMed

Charbonneau, Deborah H

2012-01-01

More women are frequently referring to the Internet for health information, yet the readability of information about menopause on the Internet has not been widely studied. To address this gap, this study examined the readability of information about menopause on 25 Internet Web sites. Findings included that information on the Web sites had a reading level higher than the recommended sixth-grade level, and culturally appropriate health information was lacking. Health educators and practitioners are in a pivotal role to help women understand information useful for healthcare decisions. Several criteria are discussed to help practitioners evaluate Web sites.

Assessment of Low-Cost Elevators for Near Term Application in Transit Stations

DOT National Transportation Integrated Search

1982-09-01

This study of low-cost elevators for use in existing transit stations was commissioned by the Transportation Systems Center and included a four-day site study of screw column elevators manufactured by the Ebel Company of Brussels, Belgium. The site s...

Physical oceanographic data from the OTEC Punta Tuna, Puerto Rico Site, September 1979-June 1980

DOE Office of Scientific and Technical Information (OSTI.GOV)

Frye, D.; Davison, A.; Leavitt, K.

1981-01-01

The first results of an oceanographic measurement program being conducted off the southeast corner of Puerto Rico are presented. The study site is a proposed OTEC site and is located about 20 km off Punta Tuna. The objectives of the measurement program are to document the physical oceanography of the site as related to the engineering and environmental factors involved in OTEC design and operation. Oceanographic measurements include: (1) a subsurface mooring instrumented with five current, temperature, and pressure recorders; and (2) quarterly hydrographic cruises to measure salinity, temperature, and depth profiles on a grid of 33 stations in themore » vicinity of the mooring site. The first cruise, conducted between 16 and 21 June 1980, included the initial mooring deployment and a CTD (conductivity, temperature, and depth) and XBT (expendable bathythermograph) survey. The CTD/XBT measurements are presented. Also included are results of in situ current, temperature, and pressure measurements made during two previous programs. In September 1979, Coastal Marine Research (CMR) deployed a mooring at approximately the same site as the present mooring. Results from three of these instruments are included. The Naval Underwater Systems Center deployed a mooring at this site in February 1979 and partial results from one instrument on this mooring are also presented. (WHK)« less

Aspects of Carbon and Sulfur Transformations in MOFEP Surface Soils

Treesearch

Henry G. Spratt

1997-01-01

Carbon and sulfur transformations were studied in surface soils from plots in MOFEP sites from August 1993 to May 1996 and in plots in watersheds ofMOFEP sites 1, 3, and 4 from May 1995 to May 1996. Element pools measured included total carbon, total sulfur, sulfate, and organic sulfur. Transformations quantified included lignocellulose mineralization and organic...

Personal Exposure, Behavior, and Work Site Conditions as Determinants of Blood Lead Among Bridge Painters

PubMed Central

Rodrigues, Ema G.; Virji, M. Abbas; McClean, Michael D.; Weinberg, Janice; Woskie, Susan; Pepper, Lewis D.

2009-01-01

Bridge painters are exposed to lead during several job tasks performed during the workday, such as sanding, scraping, and blasting. After the Occupational Safety and Health Administration standard was passed in 1993 to control lead exposures among construction workers including bridge painters, this study was conducted among 84 bridge painters in the New England area to determine the significant predictors of blood lead levels. Lead was measured in personal air and hand wipe samples that were collected during the 2-week study period and in blood samples that were collected at the beginning and at the end of the study period. The personal air and hand wipe data as well as personal behaviors (i.e., smoking, washing, wearing a respirator) and work site conditions were analyzed as potential determinants of blood lead levels using linear mixed effects models. Our results show that the mean air lead levels over the 2-week period were the most predictive exposure measure of blood lead levels. Other individual-level significant predictors of blood lead levels included months worked on bridge painting crews, education, and personal hygiene index. Of the site-level variables investigated, having a containment facility on site was a significant predictor of blood lead levels. Our results also indicate that hand wipe lead levels were significantly associated with higher blood lead levels at the end of the study period compared with the beginning of the study period. Similarly, smoking on site and respirator fit testing were significantly associated with higher blood lead levels at the end of the study period. This study shows that several individual-level and site-level factors are associated with blood lead levels among bridge painters, including lead exposure through inhalation and possible hand-to-mouth contact, personal behaviors such as smoking on site, respirator fit testing, and work site conditions such as the use of better containment facilities. Accordingly, reduction in blood lead levels among bridge painters can be achieved by improving these workplace practices. PMID:19953411

Crustal dynamics project data analysis, 1986. Volume 1: Fixed station VLBI geodetic results

NASA Technical Reports Server (NTRS)

Ma, C.; Ryan, J. W.

1987-01-01

The Goddard VLBI group reports the results of analyzing 361 Mark III VLBI data sets from fixed observatories through the end of 1985 which are available to the Crustal Dynamics Project. All POLARIS/IRIS full-day data sets are included. The mobile VLBI sites at Platteville, Colorado; Penticton, British Columbia; and Yellowknife, Northwest Territories are also included since these occupations bear on the study of plate stability. Two large solutions, GLB027 and GLB028, were used to obtain site/baseline evolutions and earth rotation parameters, respectively. Source positions and nutation offsets were also adjusted in each solution. The results include 23 sites and 101 baselines.

A Mechanism-Based Model for the Prediction of the Metabolic Sites of Steroids Mediated by Cytochrome P450 3A4.

PubMed

Dai, Zi-Ru; Ai, Chun-Zhi; Ge, Guang-Bo; He, Yu-Qi; Wu, Jing-Jing; Wang, Jia-Yue; Man, Hui-Zi; Jia, Yan; Yang, Ling

2015-06-30

Early prediction of xenobiotic metabolism is essential for drug discovery and development. As the most important human drug-metabolizing enzyme, cytochrome P450 3A4 has a large active cavity and metabolizes a broad spectrum of substrates. The poor substrate specificity of CYP3A4 makes it a huge challenge to predict the metabolic site(s) on its substrates. This study aimed to develop a mechanism-based prediction model based on two key parameters, including the binding conformation and the reaction activity of ligands, which could reveal the process of real metabolic reaction(s) and the site(s) of modification. The newly established model was applied to predict the metabolic site(s) of steroids; a class of CYP3A4-preferred substrates. 38 steroids and 12 non-steroids were randomly divided into training and test sets. Two major metabolic reactions, including aliphatic hydroxylation and N-dealkylation, were involved in this study. At least one of the top three predicted metabolic sites was validated by the experimental data. The overall accuracy for the training and test were 82.14% and 86.36%, respectively. In summary, a mechanism-based prediction model was established for the first time, which could be used to predict the metabolic site(s) of CYP3A4 on steroids with high predictive accuracy.

The Benchmark Farm Program : a method for estimating irrigation water use in southwest Florida

USGS Publications Warehouse

Duerr, A.D.; Trommer, J.T.

1982-01-01

Irrigation water-use data are summarized in this report for 74 farms in the Southwest Florida Water Management District. Most data are for 1978-90, but 18 farms have data extending back to the early 1970's. Data include site number and location, season and year, crop type, irrigation system, monitoring method, and inches of water applied per acre. Crop types include citrus, cucumbers, pasture, peanuts, sod, strawberries, and tropical fish farms are also included. Water-application rates per growing season ranged from 0 inches per acre for several citrus and pasture sites to 239.7 inches per acre for a nursery site. The report also includes rainfall data for 12 stations throughout the study area. (USGS)

NCAR Integrated Sounding System Observations during the SOAS / SAS Field Campaign

NASA Astrophysics Data System (ADS)

Brown, W. O.; Moore, J.

2013-12-01

The National Center for Atmospheric Research (NCAR) Earth Observing Laboratory (EOL) deployed an Integrated Sounding Systems (ISS) for the SOAS (Southern Oxidant and Aerosol Study) field campaign in Alabama in the summer of 2013. The ISS was split between two sites: a former NWS site approximately 1km from the main SOAS chemistry ground site near Centerville AL, and about 20km to the south at the Alabama fish hatchery site approximately 1km from the flux tower site near Marion, AL. At the former-NWS site we launched 106 radiosonde soundings, operated a 915 MHz boundary layer radar wind profiler with RASS (Radio Acoustic Sounding System), ceilometer and various surface meteorological sensors. At the AABC site we operated a Lesosphere WIndcube 200S Doppler lidar and a Metek mini-Doppler sodar. Other NCAR facilities at the AABC site included a 45-m instrumented flux tower. This poster will present a sampling observations made by these instruments, including examples of boundary layer evolution and structure, and summarize the performance of the instrumentation.

Not in whose backyard? Minority population concentrations and noxious facility sites

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nieves, L.A.

1992-04-01

The NIMBY (not in may backyard) syndrome has become the nemesis of facility siting efforts in the USA. Given people`s reluctance to live near noxious facilities, in whose backyard are such facilities located? This study employs US county-level data to examine relative concentrations of minorities living near noxious facilities. Facility types analyzed include electric generating plants, manufacturing plants, Superfund sites, and radioactive waste disposal sites. While this study does not address which cam first, the minority population concentration or the noxious facilities, it documents their current degree of association.

Not in whose backyard Minority population concentrations and noxious facility sites

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nieves, L.A.

1992-01-01

The NIMBY (not in may backyard) syndrome has become the nemesis of facility siting efforts in the USA. Given people's reluctance to live near noxious facilities, in whose backyard are such facilities located This study employs US county-level data to examine relative concentrations of minorities living near noxious facilities. Facility types analyzed include electric generating plants, manufacturing plants, Superfund sites, and radioactive waste disposal sites. While this study does not address which cam first, the minority population concentration or the noxious facilities, it documents their current degree of association.

Building Integrated Photovoltaic (BIPV) Roofs for Sustainability and Energy Efficiency

DTIC Science & Technology

2013-09-10

roofs that utilize a-Si PV modules, like the ones in this study , experienced a significantly lower price reduction, which makes them less cost...facility did not matter, a roof in need of replacement was a better use of the funds. As for Site III, since one of the objectives was to study the...at Site II (NAS Patuxent River) and Site III (MCAS Yuma). Equipment regarding the study of the load on the HVAC system, including measuring the

Library Facility Siting and Location Handbook. The Greenwood Library Management Collection.

ERIC Educational Resources Information Center

Koontz, Christine M.

This handbook is a guide to the complex process of library facility siting and location. It includes relevant research and professionals' siting experiences, as well as actual case studies of closures, openings, mergers, and relocations of library facilities. While the bulk of the volume provides practical information, the work also presents an…

Sulfometuron methyl: Its use in forestry and potential phytotoxicity

Treesearch

Nathan D. Robertson; Anthony S. Davis

2010-01-01

Planting site preparation is a common practice used to enhance seedling establishment success. Site preparations include herbicide, fire, and mechanical methods. Studies designed to explore the use of herbicides as site preparation and release tools are common, and herbicides have shown their use in forestry to be logistically, economically, and ecologically...

Loblolly Pine Growth 16 Years After Four Site Preparation Treatments

Treesearch

John C. Adams; Clyde Vidrine

2002-01-01

Thirteen-year growth results of 1-0 planted loblolly pine seedlings (Pinus taeda L.) on differently prepared upland mixed pine-hardwood sites located in north western Louisiana are presented. The study was designed as a randomized complete block consisting of three blocks of four site preparation treatments, which included: chop and burn, windrow,...

Social Media. Research Brief

ERIC Educational Resources Information Center

Williamson, Ronald

2010-01-01

The growing use of social media by students and adults is impacting schools. A recent Pew study found that 73% of teens use social-networking sites to connect with others. Social media includes blogs, wikis, and podcasts as well as sites such as MySpace, Facebook, and Linkedin. While such sites promote connection with others, their use has created…

Quantitative Analysis of Focused A-To-I RNA Editing Sites by Ultra-High-Throughput Sequencing in Psychiatric Disorders

PubMed Central

Zhu, Hu; Urban, Daniel J.; Blashka, Jared; McPheeters, Matthew T.; Kroeze, Wesley K.; Mieczkowski, Piotr; Overholser, James C.; Jurjus, George J.; Dieter, Lesa; Mahajan, Gouri J.; Rajkowska, Grazyna; Wang, Zefeng; Sullivan, Patrick F.; Stockmeier, Craig A.; Roth, Bryan L.

2012-01-01

A-to-I RNA editing is a post-transcriptional modification of single nucleotides in RNA by adenosine deamination, which thereby diversifies the gene products encoded in the genome. Thousands of potential RNA editing sites have been identified by recent studies (e.g. see Li et al, Science 2009); however, only a handful of these sites have been independently confirmed. Here, we systematically and quantitatively examined 109 putative coding region A-to-I RNA editing sites in three sets of normal human brain samples by ultra-high-throughput sequencing (uHTS). Forty of 109 putative sites, including 25 previously confirmed sites, were validated as truly edited in our brain samples, suggesting an overestimation of A-to-I RNA editing in these putative sites by Li et al (2009). To evaluate RNA editing in human disease, we analyzed 29 of the confirmed sites in subjects with major depressive disorder and schizophrenia using uHTS. In striking contrast to many prior studies, we did not find significant alterations in the frequency of RNA editing at any of the editing sites in samples from these patients, including within the 5HT2C serotonin receptor (HTR2C). Our results indicate that uHTS is a fast, quantitative and high-throughput method to assess RNA editing in human physiology and disease and that many prior studies of RNA editing may overestimate both the extent and disease-related variability of RNA editing at the sites we examined in the human brain. PMID:22912834

Treating pain on skin graft donor sites: Review and clinical recommendations.

PubMed

Sinha, Sarthak; Schreiner, Amanda J; Biernaskie, Jeff; Nickerson, Duncan; Gabriel, Vincent A

2017-11-01

Split-thickness skin grafting is the most common reconstructive procedure in managing burn injuries. Harvesting split-thickness skin creates a new partial thickness wound referred to as the donor site. Pain at the donor site is reported to be one of the most distressing symptoms during the early postoperative period. Here, we (a) identify strategies for managing donor site pain, (b) assess the quality of individual studies, and (c) formulate evidence-based recommendations based on the amount and consistency of evidence. Our analysis revealed five distinct approaches to minimize donor site pain. These include: continuous subcutaneous local anesthetic infusion (three studies), subcutaneous anesthetic injection (five studies), topical agents (six studies), nonpharmacological interventions (three studies), and wound dressings (18 studies). Available randomized control trials typically evaluated pain on standardized scales (i.e. Visual Analog Scale, Numerical Rating Scale), and compared the experimental group with standard care. Recommended treatments include: (a) subcutaneous anesthetic injection of adrenaline-lidocaine; (b) ice application; (c) topical agents, such as lidocaine and bupivacaine; and (d) hydrocolloid- and polyurethane-based wound dressings accompanied with fibrin sealant. Methodologically sound randomized control trials examining the efficacy of modified tumescent solution, ropivacaine, plasma therapy, noncontact ultrasound, and morphine gels are lacking and should be a priority for future research.

Bridge scour countermeasure assessments at select bridges in the United States, 2014–16

USGS Publications Warehouse

Dudunake, Taylor J.; Huizinga, Richard J.; Fosness, Ryan L.

2017-05-23

In 2009, the Federal Highway Administration published Hydraulic Engineering Circular No. 23 (HEC-23) to provide specific design and implementation guidelines for bridge scour and stream instability countermeasures. However, the effectiveness of countermeasures implemented over the past decade following those guidelines has not been evaluated. Therefore, in 2013, the U.S. Geological Survey, in cooperation with the Federal Highway Administration, began a study to assess the current condition of bridge-scour countermeasures at selected sites to evaluate their effectiveness. Bridge-scour countermeasures were assessed during 2014-2016. Site assessments included reviewing countermeasure design plans, summarizing the peak and daily streamflow history, and assessments at each site. Each site survey included a photo log summary, field form, and topographic and bathymetric geospatial data and metadata. This report documents the study area and site-selection criteria, explains the survey methods used to evaluate the condition of countermeasures, and presents the complete documentation for each countermeasure assessment.

A GIS-BASED MULTI-CRITERIA EVALUATION SYSTEM FOR SELECTION OF LANDFILL SITES: a case study from Abu Dhabi, United Arab Emirates

NASA Astrophysics Data System (ADS)

Issa, S. M.; Shehhi, B. Al

2012-07-01

Landfill sites receive 92% of total annual solid waste produced by municipalities in the emirate of Abu Dhabi. In this study, candidate sites for an appropriate landfill location for the Abu Dhabi municipal area are determined by integrating geographic information systems (GIS) and multi-criteria evaluation (MCE) analysis. To identify appropriate landfill sites, eight input map layers including proximity to urban areas, proximity to wells and water table depth, geology and topography, proximity to touristic and archeological sites, distance from roads network, distance from drainage networks, and land slope are used in constraint mapping. A final map was generated which identified potential areas showing suitability for the location of the landfill site. Results revealed that 30% of the study area was identified as highly suitable, 25% as suitable, and 45% as unsuitable. The selection of the final landfill site, however, requires further field research.

WIND-TUNNEL SIMULATIONS TO ASSESS DISPERSION AROUND THE WORLD TRADE CENTER SITE

EPA Science Inventory

A wind-tunnel study was conducted of dispersion from the site of the destroyed World Trade Center (WTC) in New York City. A scale model of lower Manhattan, including a scaled representation of the rubble pile, was constructed. The first phases of the study involved smoke visua...

Hanford Site Environmental Surveillance Data Report for Calendar Year 2000

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bisping, Lynn E.

2001-09-27

This data report contains the actual raw data used to create tables and summaries in the Hanford Site Environmental Report 2000. This report also includes data from special sampling studies performed in 2000.

A climatological description of the Savannah River Site

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hunter, C.H.

1990-05-22

This report provides a general climatological description of the Savannah River Site. The description provides both regional and local scale climatology. The regional climatology includes a general regional climatic description and presents information on occurrence frequencies of the severe meteorological phenomena that are important considerations in the design and siting of a facility. These phenomena include tornadoes, thunderstorms, hurricanes, and ice/snow storms. Occurrence probabilities given for extreme tornado and non-tornado winds are based on previous site specific studies. Local climatological conditions that are significant with respect to the impact of facility operations on the environment are described using on-site ormore » near-site meteorological data. Summaries of wind speed, wind direction, and atmospheric stability are primarily based on the most recently generated five-year set of data collected from the onsite meteorological tower network (1982--86). Temperature, humidity, and precipitation summaries include data from SRL's standard meteorological instrument shelter and the Augusta National Weather Service office at Bush Field through 1986. A brief description of the onsite meteorological monitoring program is also provided. 24 refs., 15 figs., 22 tabs.« less

Long-Term Environmental Research Programs - Evolving Capacity for Discovery

NASA Astrophysics Data System (ADS)

Swanson, F. J.

2008-12-01

Long-term forestry, watershed, and ecological research sites have become critical, productive nodes for environmental science research and in some cases for work in the social sciences and humanities. The Forest Service's century-old Experimental Forests and Ranges and the National Science Foundation's 28- year-old Long-Term Ecological Research program have been remarkably productive in both basic and applied sciences, including characterization of acid rain and old-growth ecosystems and development of forest, watershed, and range management systems for commercial and other land use objectives. A review of recent developments suggests steps to enhance the function of collections of long-term research sites as interactive science networks. The programs at these sites have evolved greatly, especially over the past few decades, as the questions addressed, disciplines engaged, and degree of science integration have grown. This is well displayed by small, experimental watershed studies, which first were used for applied hydrology studies then more fundamental biogeochemical studies and now examination of complex ecosystem processes; all capitalizing on the legacy of intensive studies and environmental monitoring spanning decades. In very modest ways these collections of initially independent sites have functioned increasingly as integrated research networks addressing inter-site questions by using common experimental designs, being part of a single experiment, and examining long-term data in a common analytical framework. The network aspects include data sharing via publicly-accessible data-harvester systems for climate and streamflow data. The layering of one research or environmental monitoring network upon another facilitates synergies. Changing climate and atmospheric chemistry highlight a need to use these networks as continental-scale observatory systems for assessing the impacts of environmental change on ecological services. To better capitalize on long-term research sites and networks, agencies and universities 1) need to encourage collaboration among sites and between science and land manager communities while 2) maintaining long- term studies and monitoring efforts, and staffing the collaboration in each partner organization, including positions specifically designated as liaisons among the participating communities.

1976 water-quality data in Bear Creek basin, Medford, Oregon

USGS Publications Warehouse

McKenzie, Stuart W.; Wittenberg, Loren A.

1977-01-01

The U.S. Geological Survey, in cooperation with the Rogue Valley Council of Governments, is studying surface-water-quality problems and their causes in the Bear Creek basin of southwestern Oregon. Two specific areas of investigation include: measurements of the quality and quantity of water in the irrigation canals and drainage system and the diel (during a 24-hour period) variation of water-quality parameters in the main stem of Bear Creek. The irrigation and drainage study involves 25 sites in canals and natural drainageways. One hundred thirty-three samples were collected for analysis, and discharge was determined at the time of collection. The diel study includes six sites on Bear Creek. On August 23-24, four parameters were monitored at all six sites during a 24-hour period.

X-ray and synchrotron methods in studies of cultural heritage sites

DOE Office of Scientific and Technical Information (OSTI.GOV)

Koval’chuk, M. V.; Yatsishina, E. B.; Blagov, A. E.

2016-09-15

X-ray and synchrotron methods that are most widely used in studies of cultural heritage objects (including archaeological sites)—X-ray diffraction analysis, X-ray spectroscopy, and visualization techniques— have been considered. The reported examples show high efficiency and informativeness of natural science studies when solving most diverse problems of archaeology, history, the study of art, museology, etc.

Measurements of the surface energy budget in the southern Gobi Desert of China, and in the Rocky Mountains of Colorado

NASA Technical Reports Server (NTRS)

Reiter, E. R.; Smith, E. A.; Sheaffer, J. D.

1985-01-01

Observations of the land surface energy balance were made in the Gobi desert and at two mountain sites in northern Colorado. The Gobi study included 12 days of observations in spring (April 8 to 20, 1984) and 31 days in summer at the same site (June 17 to July 18, 1984). The Colorado study included 126 days (March 13 to July 17, 1984) at a valley site and 34 days (July 31 to September 3, 1984) at a mountain top location. The data for each study included continuous observations of upward and downward radiative fluxes in three wave bands, soil temperature and moisture at four levels, air temperature and humidity at four levels and UVW wind components at three levels. Analyses of the Gobi data include definition of the impact of variable atmospheric moisture on the surface energy balance between spring and summer. In addition, diurnal wind circulations forced by heating of the northern edge of the Tibetan Plateau were observed during both periods.

CENSUS AND STATISTICAL CHARACTERIZATION OF SOIL AND WATER QUALITY AT ABANDONED AND OTHER CENTRALIZED AND COMMERCIAL DRILLING-FLUID DISPOSAL SITES IN LOUISIANA, NEW MEXICO, OKLAHOMA, AND TEXAS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alan R. Dutton; H. Seay Nance

2003-06-01

Commercial and centralized drilling-fluid disposal (CCDD) sites receive a portion of spent drilling fluids for disposal from oil and gas exploration and production (E&P) operations. Many older and some abandoned sites may have operated under less stringent regulations than are currently enforced. This study provides a census, compilation, and summary of information on active, inactive, and abandoned CCDD sites in Louisiana, New Mexico, Oklahoma, and Texas, intended as a basis for supporting State-funded assessment and remediation of abandoned sites. Closure of abandoned CCDD sites is within the jurisdiction of State regulatory agencies. Sources of data used in this study onmore » abandoned CCDD sites mainly are permit files at State regulatory agencies. Active and inactive sites were included because data on abandoned sites are sparse. Onsite reserve pits at individual wells for disposal of spent drilling fluid are not part of this study. Of 287 CCDD sites in the four States for which we compiled data, 34 had been abandoned whereas 54 were active and 199 were inactive as of January 2002. Most were disposal-pit facilities; five percent were land treatment facilities. A typical disposal-pit facility has fewer than 3 disposal pits or cells, which have a median size of approximately 2 acres each. Data from well-documented sites may be used to predict some conditions at abandoned sites; older abandoned sites might have outlier concentrations for some metal and organic constituents. Groundwater at a significant number of sites had an average chloride concentration that exceeded nonactionable secondary drinking water standard of 250 mg/L, or a total dissolved solids content of >10,000 mg/L, the limiting definition for underground sources of drinking water source, or both. Background data were lacking, however, so we did not determine whether these concentrations in groundwater reflected site operations. Site remediation has not been found necessary to date for most abandoned CCDD sites; site assessments and remedial feasibility studies are ongoing in each State. Remediation alternatives addressed physical hazards and potential for groundwater transport of dissolved salt and petroleum hydrocarbons that might be leached from wastes. Remediation options included excavation of wastes and contaminated adjacent soils followed by removal to permitted disposal facilities or land farming if sufficient on-site area were available.« less

Hydrogeologic data for the Big River-Mishnock River stream-aquifer system, central Rhode Island

USGS Publications Warehouse

Craft, P.A.

2001-01-01

Hydrogeology, ground-water development alternatives, and water quality in the BigMishnock stream-aquifer system in central Rhode Island are being investigated as part of a long-term cooperative program between the Rhode Island Water Resources Board and the U.S. Geological Survey to evaluate the ground-water resources throughout Rhode Island. The study area includes the Big River drainage basin and that portion of the Mishnock River drainage basin upstream from the Mishnock River at State Route 3. This report presents geologic data and hydrologic and water-quality data for ground and surface water. Ground-water data were collected from July 1996 through September 1998 from a network of observation wells consisting of existing wells and wells installed for this study, which provided a broad distribution of data-collection sites throughout the study area. Streambed piezometers were used to obtain differences in head data between surface-water levels and ground-water levels to help evaluate stream-aquifer interactions throughout the study area. The types of data presented include monthly ground-water levels, average daily ground-water withdrawals, drawdown data from aquifer tests, and water-quality data. Historical water-level data from other wells within the study area also are presented in this report. Surface-water data were obtained from a network consisting of surface-water impoundments, such as ponds and reservoirs, existing and newly established partial-record stream-discharge sites, and synoptic surface-water-quality sites. Water levels were collected monthly from the surface-water impoundments. Stream-discharge measurements were made at partial-record sites to provide measurements of inflow, outflow, and internal flow throughout the study area. Specific conductance was measured monthly at partial-record sites during the study, and also during the fall and spring of 1997 and 1998 at 41 synoptic sites throughout the study area. General geologic data, such as estimates of depth to bedrock and depth to water table, as well as indications of underlying geologic structure, were obtained from geophysical surveys. Site-specific geologic data were collected during the drilling of observation wells and test holes. These data include depth to bedrock or refusal, depth to water table, and lithologic information.

Remedial investigation/feasibility study badger army ammunition plant Baraboo, Wisconsin. Volume 2. Feasibility study report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1994-08-01

This Feasibility Study (FS) report for the Badger Army Ammunition Plant (BAAP) in Baraboo, Wisconsin, was prepared by ABB Environmental Services, Inc. (ABB-ES) as a component of Task Order 1 of Contract DAAAl5-91-D-OOO8 with the U.S. Army Environmental Center (USAEC). This report uses the results presented in the Final Remedial Investigation (RI) report (ABB-ES, 1993a) to develop and screen alternatives for remediation of contaminated media at BAAP. The purpose of this FS report is to develop, screen, and evaluate site-specific remedial alternatives to mitigate the impact of site-derived chemicals and ultimately provide protection of human health and the environment. Preferredmore » alternatives for each site are included in this report. Based on previous environmental studies at BAAP, 11 potential hazardous waste sites were ranked according to potential contributions of hazardous chemicals to the environment. These sites were designated as Waste Management Areas because some of the sites contain multiple Solid Waste Management Units (SWMUs). The sites selected to undergo facility assessment and corrective actions are: the Propellant Burning Ground (including Landfill), Deterrent Burning Ground, existing Landfill, Settling Ponds and Spoils Disposal Area, Rocket Paste Area, Oleum Plant and Oleum Plant Pond, Nitroglycerine Pond, old Acid Area, new Acid Area, and Ballistics Pond. The USAEC added an 11th site, the Old Fuel Oil Tank, to the list in October 1989 after discovery of fuel-contaminated soils during excavation of a water line in the vicinity of the old fuel oil tank foundation.« less

Remedial investigation/feasibility study badger army ammunition plant Baraboo, Wisconsin. Volume 3. Feasibility study report (Final)

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1994-08-01

This Feasibility Study (FS) report for the Badger Army Ammunition Plant (BAAP) in Baraboo, Wisconsin, was prepared by ABB Environmental Services, Inc. (ABB-ES) as a component of Task Order 1 of Contract DAAAl5-91-D-OOO8 with the U.S. Army Environmental Center (USAEC). This report uses the results presented in the Final Remedial Investigation (RI) report (ABB-ES, 1993a) to develop and screen alternatives for remediation of contaminated media at BAAP. The purpose of this FS report is to develop, screen, and evaluate site-specific remedial alternatives to mitigate the impact of site-derived chemicals and ultimately provide protection of human health and the environment. Preferredmore » alternatives for each site are included in this report. Based on previous environmental studies at BAAP, 11 potential hazardous waste sites were ranked according to potential contributions of hazardous chemicals to the environment. These sites were designated as Waste Management Areas because some of the sites contain multiple Solid Waste Management Units (SWMUs). The sites selected to undergo facility assessment and corrective actions are: the Propellant Burning Ground (including Landfill), Deterrent Burning Ground, existing Landfill, Settling Ponds and Spoils Disposal Area, Rocket Paste Area, Oleum Plant and Oleum Plant Pond, Nitroglycerine Pond, old Acid Area, new Acid Area, and Ballistics Pond. The USAEC added an 11th site, the Old Fuel Oil Tank, to the list in October 1989 after discovery of fuel-contaminated soils during excavation of a water line in the vicinity of the old fuel oil tank foundation.« less

Remedial investigation/feasibility study badger army ammunition plant Baraboo, Wisconsin. Volume 1. Feasibility study report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1994-08-01

This Feasibility Study (FS) report for the Badger Army Ammunition Plant (BAAP) in Baraboo, Wisconsin, was prepared by ABB Environmental Services, Inc. (ABB-ES) as a component of Task Order 1 of Contract DAAAl5-91-D-OOO8 with the U.S. Army Environmental Center (USAEC). This report uses the results presented in the Final Remedial Investigation (RI) report (ABB-ES, 1993a) to develop and screen alternatives for remediation of contaminated media at BAAP. The purpose of this FS report is to develop, screen, and evaluate site-specific remedial alternatives to mitigate the impact of site-derived chemicals and ultimately provide protection of human health and the environment. Preferredmore » alternatives for each site are included in this report. Based on previous environmental studies at BAAP, 11 potential hazardous waste sites were ranked according to potential contributions of hazardous chemicals to the environment. These sites were designated as Waste Management Areas because some of the sites contain multiple Solid Waste Management Units (SWMUs). The sites selected to undergo facility assessment and corrective actions are: the Propellant Burning Ground (including Landfill), Deterrent Burning Ground, existing Landfill, Settling Ponds and Spoils Disposal Area, Rocket Paste Area, Oleum Plant and Oleum Plant Pond, Nitroglycerine Pond, old Acid Area, new Acid Area, and Ballistics Pond. The USAEC added an 11th site, the Old Fuel Oil Tank, to the list in October 1989 after discovery of fuel-contaminated soils during excavation of a water line in the vicinity of the old fuel oil tank foundation.« less

Health Risks to Ecological Workers on Contaminated Sites - the Department of Energy as a Case Study

PubMed Central

Burger, Joanna; Gochfeld, Michael

2016-01-01

Background At most contaminated sites the risk to workers focuses on those ‘hazardous waste workers’ directly exposed to chemicals or radionuclides, and to the elaborate approaches implemented to protecting their health and safety. Ecological workers generally are not considered. Objectives To explore the risks to the health and safety of ecological workers on sites with potential chemical and radiological exposures before, during or after remediation of contamination. To use the U.S. Department of Energy as a case study, and to develop concepts that apply generally to sites contaminated with hazardous or nuclear wastes, Methods Develop categories of ecological workers, describe their usual jobs, and provide information on the kinds of risks they face. Ecological activities include continued surveillance and monitoring work on any sites with residual contamination, subject to institutional controls and engineered barriers following closure as well as the restoration. Results The categories of ecological workers and their tasks include 1) Ecological characterization, mapping and monitoring, 2) biodiversity studies, 2) Contaminant fate and transport, 3) On-going industrial activities 4) Remediation activities (environmental management), 5) Environmental restoration, 6) Post-cleanup surveillance and monitoring, and 7) Post-closure future site activities. There are a set of functional activities that can occur with different frequencies and intensities, including visual inspection, collecting biological samples, collecting media physical samples, collecting biological debris, restoration planting, and maintaining ecosystems. Conclusions Ecological workers face different exposures and risks than other environmental cleanup workers. Many of their tasks mimic shift work with long hours leading to fatigue, and they are exposed to biological as well as chemical/radiological hazards. DOE and other entities need to examine the risks to ecological workers on site with an eye to risk reduction. PMID:27668128

Outcomes After Radiation Therapy to Metastatic Sites in Patients With Stage 4 Neuroblastoma

PubMed Central

Kandula, Shravan; Prabhu, Roshan S.; Nanda, Ronica; Switchenko, Jeffrey M.; Cash, Thomas; Qayed, Muna; Katzenstein, Howard; Esiashvili, Natia

2016-01-01

Summary In patients with high-risk metastatic neuroblastoma, the benefit of radiation therapy (RT) to metastatic sites as part of primary treatment has not been fully investigated. The purpose of this single-institution study was to evaluate local control of irradiated metastatic sites, and characterize metastatic disease burden and anatomic distribution in patients with high-risk metastatic neuroblastoma. The records of all patients diagnosed with stage 4 neuroblastoma between August 2000 and January 2010 were reviewed. Exclusion criteria included: bone-marrow only metastatic site, total body irradiation, or no imaging follow-up. A total of 37 patients met eligibility criteria. Median follow-up period for patients without relapse was 61 months. Five-year overall survival for all patients was 67%. Thirteen patients (35%) received RT to a metastatic site as part of their primary treatment. Among these patients, in-field recurrence occurred in three patients (23%), including two of three treated calvarial sites. In patients treated with or without RT to a metastatic site, respectively, there was no significant difference in 5-year overall survival (73% vs. 63%, P = 0.84) or relapse-free survival (46% and 55%, P = 0.48). Current metastatic site RT dose may be suboptimal, and certain locations may predict for a poor response. Further studies are necessary to elucidate the optimal role of RT to metastatic sites. PMID:25238225

Hydrogeologic for the Saco River valley glacial aquifer from Bartlett, New Hampshire to Fryeburg, Maine; October 1983 through January 1986

USGS Publications Warehouse

Johnson, C.D.; Tepper, D.H.; Morrissey, D.J.

1987-01-01

Hydrogeologic data was collected for a study of the Saco River valley glacial aquifer. The study area extends along the Saco River from Bartlett, New Hampshire to Fryeburg, Maine. The study was done in cooperation with the Maine Geological Survey (Department of Conservation), the New Hampshire Water Supply and Pollution Control Commission, the New Hampshire Water Resources Board, and the Town of Conway, New Hampshire. The data include information on 54 well-inventory sites, 69 exploration-hole logs , analyses of grain-size distribution in 130 samples of glacial sediments, monthly water-table measurements in 100 wells, and continuous water-table measurements in 7 wells. Discharge data are presented from 6 stream-gaging stations operated for this study during the 1984 and 1985 water years. Data from 50 sets of seepage runs and 15 miscellaneous discharge measurements conducted on the mainstream of the Saco River and on 7 tributary streams during the 1984 and 1985 water years are also presented. Water quality analyses of groundwater samples from 92 sites and surface water samples from 12 sites are presented. Field determinations include pH, temperature, and specific conductance. Laboratory determinations include nutrients, common inorganic anions and cations, selected volatile organic compounds, and detergents. Maps show the locations of data-collection sites. (USGS)

Nuclear facility decommissioning and site remedial actions: A selected bibliography: Volume 8

DOE Office of Scientific and Technical Information (OSTI.GOV)

Owen, P.T.; Michelson, D.C.; Knox, N.P.

1987-09-01

The 553 abstracted references on nuclear facility decommissioning, uranium mill tailings management, and site remedial actions constitute the eighth in a series of reports. Foreign and domestic literature of all types - technical reports, progress reports, journal articles, symposia proceedings, theses, books, patents, legislation, and research project descriptions - has been included. The bibliography contains scientific, technical, economic, regulatory, and legal information pertinent to the US Department of energy's remedial action program. Major chapters are Surplus Facilities Management Program, Nuclear Facilities Decommissioning, Formerly Utilized Sites Remedial Action Program, Facilities Contaminated with Naturally Occurring Radionuclides, Uranium Mill Tailings Remedial Action Program,more » Uranium Mill Tailings Management, Technical Measurements Center, and General Remedial Action Program Studies. Chapter sections for chapters 1, 2, 5, and 6 include Design, Planning, and Regulations; Environmental Studies and Site Surveys; Health, Safety, and Biomedical Studies; Decontamination Studies; Dismantlement and Demolition; Site Stabilization and Reclamation; Waste Disposal; Remedial Action Experience; and General Studies. Within these categories, references are arranged alphabetically by first author. Those references having no individual author are listed by corporate affiliation or by publication description. Indexes are provided for author, corporate affiliation, title word, publication description, geographic location, and keywords. The appendix contains a list of frequently used acronyms and abbreviations.« less

Comparisons between two biochemical markers in evaluating periodontal disease severity: a cross-sectional study

PubMed Central

2014-01-01

Background The purpose of this study was to compare two biochemical markers, which have been previously used to determine the degrees of alveolar bone destruction, in evaluating periodontal disease severity. Methods The WF6 epitope of chondroitin sulfate (CS) and the alkaline phosphatase (ALP) levels were determined in gingival crevicular fluid (GCF) samples collected from patients with various degrees of disease severity, including ten patients with gingivitis (50 gingivitis sites) and 33 patients with chronic periodontitis (including gingivitis, slight, moderate, and severe periodontitis sites; n = 50 each), as well as from ten healthy volunteers (50 healthy sites) by Periopaper strips. The levels of CS and ALP were measured by an ELISA and a fluorometric assay, respectively. Results The results demonstrated low levels of CS and ALP in non-destructive and slightly destructive periodontitis sites, whereas significantly high levels of these two biomolecules were shown in moderately and severely destructive sites (p < 0.05). Although a significant difference in CS levels was found between moderate and severe periodontitis sites, no difference in ALP levels was found. Stronger correlations were found between CS levels and periodontal parameters, including probing depth, loss of clinical attachment levels, gingival index and plaque index, than between ALP levels and these parameters. Conclusions It is suggested that the CS level is a better diagnostic marker than the ALP level for evaluating distinct severity of chronic periodontitis. PMID:25174345

Infant Gastroesophageal Reflux Information on the World Wide Web.

PubMed

Balgowan, Regina; Greer, Leah C; D'Auria, Jennifer P

2016-01-01

The purpose of this study was to describe the type and quality of health information about infant gastroesophageal reflux (GER) that a parent may find on the World Wide Web. The data collection tool included evaluation of Web site quality and infant GER-specific content on the 30 sites that met the inclusion criteria. The most commonly found content categories in order of frequency were management strategies, when to call a primary care provider, definition, and clinical features. The most frequently mentioned strategies included feeding changes, infant positioning, and medications. Thirteen of the 30 Web sites included information on both GER and gastroesophageal reflux disease. Mention of the use of medication to lessen infant symptoms was found on 15 of the 30 sites. Only 10 of the 30 sites included information about parent support and coping strategies. Pediatric nurse practitioners (PNPs) should utilize well-child visits to address the normalcy of physiologic infant GER and clarify any misperceptions parents may have about diagnosis and the role of medication from information they may have found on the Internet. It is critical for PNPs to assist in the development of Web sites with accurate content, advise parents on how to identify safe and reliable information, and provide examples of high-quality Web sites about child health topics such as infant GER. Copyright © 2016 National Association of Pediatric Nurse Practitioners. Published by Elsevier Inc. All rights reserved.

Meeting Reference Responsibilities through Library Web Sites.

ERIC Educational Resources Information Center

Adams, Michael

2001-01-01

Discusses library Web sites and explains some of the benefits when libraries make their sites into reference portals, linking them to other useful Web sites. Topics include print versus Web information sources; limitations of search engines; what Web sites to include, including criteria for inclusions; and organizing the sites. (LRW)

Students as Web Site Authors: Effects on Motivation and Achievement

ERIC Educational Resources Information Center

Jones, Brett D.

2003-01-01

This study examined the effects of a Web site design project on students' motivation and achievement. Tenth-grade biology students worked together in teams on an ecology project that required them to locate relevant information on the Internet, decide which information should be included on their Web site, organize the information into Web pages,…

Web Analytics: A Picture of the Academic Library Web Site User

ERIC Educational Resources Information Center

Black, Elizabeth L.

2009-01-01

This article describes the usefulness of Web analytics for understanding the users of an academic library Web site. Using a case study, the analysis describes how Web analytics can answer questions about Web site user behavior, including when visitors come, the duration of the visit, how they get there, the technology they use, and the most…

Teaching World History and Global Issues with the Internet

ERIC Educational Resources Information Center

Risinger, C. Frederick

2011-01-01

In this article, the author recommends websites that include both traditional world history content and sites that focus on contemporary world issues and problems. The first two sites provide an intellectual stage for both world history and global studies. While they don't have lesson plans or links to other sites, they provide an understanding of…

Integrated ground-water monitoring strategy for NRC-licensed facilities and sites: Case study applications

USGS Publications Warehouse

Price, V.; Temples, T.; Hodges, R.; Dai, Z.; Watkins, D.; Imrich, J.

2007-01-01

This document discusses results of applying the Integrated Ground-Water Monitoring Strategy (the Strategy) to actual waste sites using existing field characterization and monitoring data. The Strategy is a systematic approach to dealing with complex sites. Application of such a systematic approach will reduce uncertainty associated with site analysis, and therefore uncertainty associated with management decisions about a site. The Strategy can be used to guide the development of a ground-water monitoring program or to review an existing one. The sites selected for study fall within a wide range of geologic and climatic settings, waste compositions, and site design characteristics and represent realistic cases that might be encountered by the NRC. No one case study illustrates a comprehensive application of the Strategy using all available site data. Rather, within each case study we focus on certain aspects of the Strategy, to illustrate concepts that can be applied generically to all sites. The test sites selected include:Charleston, South Carolina, Naval Weapons Station,Brookhaven National Laboratory on Long Island, New York,The USGS Amargosa Desert Research Site in Nevada,Rocky Flats in Colorado,C-Area at the Savannah River Site in South Carolina, andThe Hanford 300 Area.A Data Analysis section provides examples of detailed data analysis of monitoring data.

Could we do better? Behavioural tracking on recommended consumer health websites.

PubMed

Burkell, Jacquelyn; Fortier, Alexandre

2015-09-01

This study examines behavioural tracking practices on consumer health websites, contrasting tracking on sites recommended by information professionals with tracking on sites returned by Google. Two lists of consumer health websites were constructed: sites recommended by information professionals and sites returned by Google searches. Sites were divided into three groups according to source (Recommended-Only, Google-Only or both) and type (Government, Not-for-Profit or Commercial). Behavioural tracking practices on each website were documented using a protocol that detected cookies, Web beacons and Flash cookies. The presence and the number of trackers that collect personal information were contrasted across source and type of site; a second set of analyses specifically examined Advertising trackers. Recommended-Only sites show lower levels of tracking - especially tracking by advertisers - than do Google-Only sites or sites found through both sources. Government and Not-for-Profit sites have fewer trackers, particularly from advertisers, than do Commercial sites. Recommended sites, especially those from Government or Not-for-Profit organisations, present a lower privacy threat than sites returned by Google searches. Nonetheless, most recommended websites include some trackers, and half include at least one Advertising tracker. To protect patron privacy, information professionals should examine the tracking practices of the websites they recommend. © 2015 Health Libraries Group.

Evaluation of Risk Factors for Severe Pneumonia in Children: The Pneumonia Etiology Research for Child Health Study

PubMed Central

Deloria-Knoll, Maria; Feikin, Daniel R.; DeLuca, Andrea N.; Driscoll, Amanda J.; Moïsi, Jennifer C.; Johnson, Hope L.; Murdoch, David R.; O’Brien, Katherine L.; Levine, Orin S.; Scott, J. Anthony G.

2012-01-01

As a case-control study of etiology, the Pneumonia Etiology Research for Child Health (PERCH) project also provides an opportunity to assess the risk factors for severe pneumonia in hospitalized children at 7 sites. We identified relevant risk factors by literature review and iterative expert consultation. Decisions for inclusion in PERCH were based on comparability to published data, analytic plans, data collection costs and logistic feasibility, including interviewer time and subject fatigue. We aimed to standardize questions at all sites, but significant variation in the economic, cultural, and geographic characteristics of sites made it difficult to obtain this objective. Despite these challenges, the depth of the evaluation of multiple risk factors across the breadth of the PERCH sites should furnish new and valuable information about the major risk factors for childhood severe and very severe pneumonia, including risk factors for pneumonia caused by specific etiologies, in developing countries. PMID:22403226

Evaluation of risk factors for severe pneumonia in children: the Pneumonia Etiology Research for Child Health study.

PubMed

Wonodi, Chizoba B; Deloria-Knoll, Maria; Feikin, Daniel R; DeLuca, Andrea N; Driscoll, Amanda J; Moïsi, Jennifer C; Johnson, Hope L; Murdoch, David R; O'Brien, Katherine L; Levine, Orin S; Scott, J Anthony G

2012-04-01

As a case-control study of etiology, the Pneumonia Etiology Research for Child Health (PERCH) project also provides an opportunity to assess the risk factors for severe pneumonia in hospitalized children at 7 sites. We identified relevant risk factors by literature review and iterative expert consultation. Decisions for inclusion in PERCH were based on comparability to published data, analytic plans, data collection costs and logistic feasibility, including interviewer time and subject fatigue. We aimed to standardize questions at all sites, but significant variation in the economic, cultural, and geographic characteristics of sites made it difficult to obtain this objective. Despite these challenges, the depth of the evaluation of multiple risk factors across the breadth of the PERCH sites should furnish new and valuable information about the major risk factors for childhood severe and very severe pneumonia, including risk factors for pneumonia caused by specific etiologies, in developing countries.

Annual Bibliography [of Appalachian Studies], 1997.

ERIC Educational Resources Information Center

Brown, Jo B., Comp.

1998-01-01

Classified, selected bibliography for Appalachian Studies includes over 400 entries: books, journal articles, government documents, and dissertations published 1996-97. Contains 25 categories including agriculture; Appalachian Studies; architecture, historic sites; arts, crafts; Civil War; coal, industry, labor; description, travel; economic…

The role of physical habitat and sampling effort on estimates of benthic macroinvertebrate taxonomic richness at basin and site scales.

PubMed

Silva, Déborah R O; Ligeiro, Raphael; Hughes, Robert M; Callisto, Marcos

2016-06-01

Taxonomic richness is one of the most important measures of biological diversity in ecological studies, including those with stream macroinvertebrates. However, it is impractical to measure the true richness of any site directly by sampling. Our objective was to evaluate the effect of sampling effort on estimates of macroinvertebrate family and Ephemeroptera, Plecoptera, and Trichoptera (EPT) genera richness at two scales: basin and stream site. In addition, we tried to determine which environmental factors at the site scale most influenced the amount of sampling effort needed. We sampled 39 sites in the Cerrado biome (neotropical savanna). In each site, we obtained 11 equidistant samples of the benthic assemblage and multiple physical habitat measurements. The observed basin-scale richness achieved a consistent estimation from Chao 1, Jack 1, and Jack 2 richness estimators. However, at the site scale, there was a constant increase in the observed number of taxa with increased number of samples. Models that best explained the slope of site-scale sampling curves (representing the necessity of greater sampling effort) included metrics that describe habitat heterogeneity, habitat structure, anthropogenic disturbance, and water quality, for both macroinvertebrate family and EPT genera richness. Our results demonstrate the importance of considering basin- and site-scale sampling effort in ecological surveys and that taxa accumulation curves and richness estimators are good tools for assessing sampling efficiency. The physical habitat explained a significant amount of the sampling effort needed. Therefore, future studies should explore the possible implications of physical habitat characteristics when developing sampling objectives, study designs, and calculating the needed sampling effort.

Environmental health risks of toxic waste site exposures--an epidemiological perspective.

PubMed

von Schirnding, Y E; Ehrlich, R I

1992-06-06

A general account is given of the problems of assessing the impact of human exposure to toxic waste sites, including the identification of truly exposed populations and of exposure pathways. Epidemiological studies of populations at risk are briefly reviewed and methodological problems summarised. These include the use of relatively weak study designs, inadequate exposure assessment and recall biases associated with symptom reporting among anxious residents living in the vicinity of waste sites. In South Africa, health risks associated with exposure to toxic waste sites need to be viewed in the context of current community health concerns, competing causes of disease and ill-health, and the relative lack of knowledge about environmental contamination and associated health effects. A nonspecific deterioration of health and well-being is more likely to result from waste site exposures than is overt clinical disease. Socially acceptable policies and controls may have to be based on criteria other than demonstrable ill-health. Detailed inventories and registries of the nature of disposed materials need to be maintained, sites of poorly controlled disposal in the past identified and selective environmental monitoring conducted. Epidemiological studies may be justified in situations where exposures well in excess of acceptable norms are demonstrated. An integrated national waste management policy for the country is urgently needed.

Shared Opportunities on Institutional Lands: On-Site Food Production, Its Benefits, Barriers, and Opportunities.

PubMed

Knezevic, Irena; Mount, Phil; Clement, Chantal

2016-10-01

This article outlines preliminary findings of a 3-year project that explored on-site food production on institutional properties, primarily healthcare facilities. There are growing pressures on healthcare facilities to improve their food offerings and incorporate food gardens into their health programs. While several healthcare facilities produce food on-site, there are few studies that explore opportunities, capacities, and institutional barriers related to on-site food production. The study employed mixed methods including historical review, case studies, surveys, interviews, pilot garden projects, and Geographic Information System mapping. The number of participating institutions varied by method. Benefits associated with on-site food production can be health, economic, environmental, and social. There are also institutional barriers including administrative roadblocks, perceived obstacles, and the difficulty in quantitatively, measuring the qualitatively documented benefits. The benefits of food gardens far outweigh the challenges. On-site food production has tremendous potential to improve nutrition for staff and patients, offer healing spaces, better connect institutions with the communities in which they are located, and provide the long-professed benefits of gardening for all involved-from therapeutic benefits and outdoor physical activities to developing skills and social relationships in ways that few other activities do. © The Author(s) 2016.

Health impact of climate change on occupational health and productivity in Thailand

PubMed Central

Langkulsen, Uma; Vichit-Vadakan, Nuntavarn; Taptagaporn, Sasitorn

2010-01-01

Background The rise in global temperature is well documented. Changes in temperature lead to increases in heat exposure, which may impact health ranging from mild heat rashes to deadly heat stroke. Heat exposure can also aggravate several chronic diseases including cardiovascular and respiratory disease. Objective This study examined the relationship between climate condition and health status and productivity in two main categories of the occupational setting – where one setting involves heat generated from the industry and the other with heat in a natural setting. Design This cross-sectional study included four industrial sites (pottery industry, power plant, knife industry, and construction site) and one agricultural site in the Pathumthani and Ayutthaya provinces. Exposure data were comprised of meteorological data and heat exposure including relative humidity (RH) measured by Wet Bulb Globe Temperature (WBGT) monitor. Heat index was calculated to measure the effects of heat exposure on the study population, which consisted of 21 workers at five worksites; a questionnaire was also used to collect data on workers. Results Among the five workplaces, the outdoor WBGT was found to be highest at 34.6°C during 12:00 and 1:00 PM at the agricultural site. It was found that four out of five study sites had heat indices in the ‘extreme caution,’ where heat cramp and exhaustion may be possible and one site showed a value of 41°C that falls into the category of ‘danger,’ where sunstroke and heat exhaustion are likely and prolonged exposure may lead to heatstroke. Productivity as perceived by the workers revealed that only the construction and pottery industry workers had a loss of productivity ranged from 10 to 60 %. Conclusions Climate conditions in Thailand potentially affect both the health and productivity in occupational settings. PMID:21160553

Health impact of climate change on occupational health and productivity in Thailand.

PubMed

Langkulsen, Uma; Vichit-Vadakan, Nuntavarn; Taptagaporn, Sasitorn

2010-12-09

The rise in global temperature is well documented. Changes in temperature lead to increases in heat exposure, which may impact health ranging from mild heat rashes to deadly heat stroke. Heat exposure can also aggravate several chronic diseases including cardiovascular and respiratory disease. This study examined the relationship between climate condition and health status and productivity in two main categories of the occupational setting - where one setting involves heat generated from the industry and the other with heat in a natural setting. This cross-sectional study included four industrial sites (pottery industry, power plant, knife industry, and construction site) and one agricultural site in the Pathumthani and Ayutthaya provinces. Exposure data were comprised of meteorological data and heat exposure including relative humidity (RH) measured by Wet Bulb Globe Temperature (WBGT) monitor. Heat index was calculated to measure the effects of heat exposure on the study population, which consisted of 21 workers at five worksites; a questionnaire was also used to collect data on workers. Among the five workplaces, the outdoor WBGT was found to be highest at 34.6°C during 12:00 and 1:00 PM at the agricultural site. It was found that four out of five study sites had heat indices in the 'extreme caution,' where heat cramp and exhaustion may be possible and one site showed a value of 41°C that falls into the category of 'danger,' where sunstroke and heat exhaustion are likely and prolonged exposure may lead to heatstroke. Productivity as perceived by the workers revealed that only the construction and pottery industry workers had a loss of productivity ranged from 10 to 60 %. Climate conditions in Thailand potentially affect both the health and productivity in occupational settings.

CpG Sites Associated with Cigarette Smoking: Analysis of Epigenome-Wide Data from the Sister Study

PubMed Central

Harlid, Sophia; Xu, Zongli; Panduri, Vijayalakshmi; Sandler, Dale P.

2014-01-01

Background: Smoking increases the risk of many diseases, and it is also linked to blood DNA methylation changes that may be important in disease etiology. Objectives: We sought to identify novel CpG sites associated with cigarette smoking. Methods: We used two epigenome-wide data sets from the Sister Study to identify and confirm CpG sites associated with smoking. One included 908 women with methylation measurements at 27,578 CpG sites using the HumanMethylation27 BeadChip; the other included 200 women with methylation measurements for 473,844 CpG sites using the HumanMethylation450 BeadChip. Significant CpGs from the second data set that were not included in the 27K assay were validated by pyrosequencing in a subset of 476 samples from the first data set. Results: Our study successfully confirmed smoking associations for 9 previously established CpGs and identified 2 potentially novel CpGs: cg26764244 in GNG12 (p = 9.0 × 10–10) and cg22335340 in PTPN6 (p = 2.9 × 10–05). We also found strong evidence of an association between smoking status and cg02657160 in CPOX (p = 7.3 × 10–7), which has not been previously reported. All 12 CpGs were undermethylated in current smokers and showed an increasing percentage of methylation in former and never-smokers. Conclusions: We identified 2 potentially novel smoking related CpG sites, and provided independent replication of 10 previously reported CpGs sites related to smoking, one of which is situated in the gene CPOX. The corresponding enzyme is involved in heme biosynthesis, and smoking is known to increase heme production. Our study extends the evidence base for smoking-related changes in DNA methylation. Citation: Harlid S, Xu Z, Panduri V, Sandler DP, Taylor JA. 2014. CpG sites associated with cigarette smoking: analysis of epigenome-wide data from the Sister Study. Environ Health Perspect 122:673–678; http://dx.doi.org/10.1289/ehp.1307480 PMID:24704585

Geology of Potential Landing Sites for Martian Sample Returns

NASA Technical Reports Server (NTRS)

Greeley, Ronald

2003-01-01

This project involved the analysis of potential landing sites on Mars. As originally proposed, the project focused on landing sites from which samples might be returned to Earth. However, as the project proceeded, the emphasis shifted to missions that would not include sample return, because the Mars Exploration Program had deferred sample returns to the next decade. Subsequently, this project focused on the study of potential landing sites for the Mars Exploration Rovers.

Assessment of the Quality of Patient-Orientated Information on Surgery for Crohn's Disease on the Internet.

PubMed

Yeung, Trevor M; Sacchi, Matteo; Mortensen, Neil J; Spinelli, Antonino

2015-09-01

The Internet is a vast resource for patients to search for health information on the treatment of Crohn's disease. This study examines the quality of Web sites that provide information to adults regarding Crohn's disease, including treatment options and surgery. Two search engines (Google and Yahoo) and the search terms "surgery for Crohn's disease" were used. The first 50 sites of each search were assessed. Sites that fulfilled the inclusion criteria were evaluated for content and scored by using the DISCERN instrument, which evaluates the quality of health information on treatment choices. One hundred sites were examined, of which 13 were duplicates. Sixty-two sites provided patient-orientated information. The other sites included 7 scientific articles, 3 blogs, 2 links, 6 forums, 3 video links, and 4 dead links. Of the 62 Web sites that provided patient information for adults, only 15 (24.2%) had been updated within the past 2 years. Only 9 (14.5%) were affiliated with hospitals and clinics. The majority of sites (33, 53.2%) were associated with private companies with commercial interests. Only half of the Web sites provided details on treatment options, and most Web sites did not provide any information on symptoms and procedure details. Just 5 Web sites (8.1%) described the risks of surgery, and only 7 (11.3%) provided any information on the timescale for recovery. Overall, only 1 Web site (1.6%) was identified as being "good" or "excellent" with the use of the DISCERN criteria. Although the internet is constantly evolving, this study captures data at a specific time point. Search results may vary depending on geographical location. This study only assessed English language websites. The quality of patient information on surgery for Crohn's disease is highly variable and generally poor. There is potential for the Internet to provide valuable information, and clinicians should identify high-quality Web sites to guide their patients.

Studies on rock characteristics and timing of creep at selected landslide sites in Taiwan

Treesearch

Cheng-Yi Lee

2000-01-01

A study was conducted to investigate the causes of and rock characteristics at three landslide sites in the Tesngwen Reservoir watershed of southern Taiwan. Research methods used included the petrographic microscope, X-ray diffraction (XRD), scanning electron microscope (SEM), inductively coupled plasma spectroscope (ICP), constant head permeameter in triaxial...

A Multi-Site Study on Medical School Selection, Performance, Motivation and Engagement

ERIC Educational Resources Information Center

Wouters, A.; Croiset, G.; Schripsema, N. R.; Cohen-Schotanus, J.; Spaai, G. W.; Hulsman, R. L.; Kusurkar, R. A.

2017-01-01

Medical schools seek ways to improve their admissions strategies, since the available methods prove to be suboptimal for selecting the best and most motivated students. In this multi-site cross-sectional questionnaire study, we examined the value of (different) selection procedures compared to a weighted lottery procedure, which includes direct…

Seismic risk assessment of architectural heritages in Gyeongju considering local site effects

NASA Astrophysics Data System (ADS)

Park, H.-J.; Kim, D.-S.; Kim, D.-M.

2013-02-01

A seismic risk assessment is conducted for cultural heritage sites in Gyeongju, the capital of Korea's ancient Silla Kingdom. Gyeongju, home to UNESCO World Heritage sites, contains remarkable artifacts of Korean Buddhist art. An extensive geotechnical survey including a series of in situ tests is presented, providing pertinent soil profiles for site response analyses on thirty cultural heritage sites. After the shear wave velocity profiles and dynamic material properties were obtained, site response analyses were carried out at each historical site and the amplification characteristics, site period, and response spectrum of the site were determined for the earthquake levels of 2400 yr and 1000 yr return periods based on the Korean seismic hazard map. Response spectrum and corresponding site coefficients obtained from site response analyses considering geologic conditions differ significantly from the current Korean seismic code. This study confirms the importance of site-specific ground response analyses considering local geological conditions. Results are given in the form of the spatial distribution of bedrock depth, site period, and site amplification coefficients, which are particularly valuable in the context of a seismic vulnerability study. This study presents the potential amplification of hazard maps and provides primary data on the seismic risk assessment of each cultural heritage.

Fracture Characterization

EPA Science Inventory

The goal of this volume is to compare and assess various techniques for understanding fracture patterns at a site at Pease International Tradeport, NH, and to give an overview of the site as a whole. Techniques included are: core logging, geophysical logging, radar studies, and...

BLM Density Management and Riparian Buffer Study: Establishment Report and Study Plan

USGS Publications Warehouse

Cissel, John H.; Anderson, P.D.; Olson, Deanna H.; Puettmann, Klaus; Berryman, Shanti; Chan, Samuel; Thompson, Charley

2006-01-01

The Bureau of Land Management (BLM), Pacific Northwest Research Station (PNW), U.S. Geological Survey (USGS), and Oregon State University (OSU) established the BLM Density Management and Riparian Buffer Study (DMS) in 1994 to demonstrate and test options for young stand management to meet Northwest Forest Plan objectives in western Oregon. The primary objectives of the DMS are to evaluate the effects of alternative forest density management treatments in young stands on the development of important late-successional forest habitat attributes and to assess the combined effects of density management and alternative riparian buffer widths on aquatic and riparian ecosystems. The DMS consists of three integrated studies: initial thinning, rethinning, and riparian buffer widths. The initial thinning study was installed in 50- to 80-year-old stands that had never been commercially thinned. Four stand treatments of 30-60 acres each were established at each of seven study sites: (1) unthinned control, (2) high density retention [120 trees per acre (TPA)], (3) moderate density retention (80 TPA), and (4) variable density retention (40-120 TPA). Small (1/4 to 1 acre in size) leave islands were included in all treatments except the control, and small patch cuts (1/4 to 1 acre in size) were included in the moderate and variable density treatments. An eighth site, Callahan Creek, contains a partial implementation of the study design. The rethinning study was installed in four 70- to 90-year-old stands that previously had been commercially thinned. Each study stand was split into two parts: one part as an untreated control and the other part as a rethinning (30-60 TPA). The riparian buffer study was nested within the moderate density retention treatment at each of the eight initial thinning study sites and two rethinning sites. Alternative riparian buffer widths included: (1) streamside retention (one tree canopy width, or 20-25 feet), (2) variable width (follows topographic and vegetative breaks, 50 feet slope distance minimum), (3) one full site-potential tree height (approximately 220 feet), and (4) two full tree heights (approximately 440 feet). A second round of density management manipulations are now being planned for implementation beginning in 2009. Stem density will be reduced in the high, moderate, and variable density treatments and most existing riparian buffers, leave islands, and patch cuts will remain in place. Remeasurement, data management, and analysis are ongoing for three long-term, core components of the DMS: vegetation, microclimate, and aquatic vertebrates. In addition, several short-term collaborative studies have been completed on these sites, including leave island effectiveness as refugia, treatment response of terrestrial and aquatic arthropods, and smaller-scale studies of fungal, lichen, and bryophyte community response. Additional collaborative studies are encouraged on DMS sites.

A Cultural Resource and Geological Study Pertaining to Four Selected Petroglyph/Pictograph Sites on Nellis Air Force Range and Adjacent Overflight Lands, Lincoln and Nye Countries, Nevada

DTIC Science & Technology

1999-08-01

petroglyph elements from this site were included in Heizer and Baumhoff s (1962:57) classic analysis. Unfortunately, the two researchers equate Steward’s...mining camp 2 to 3 miles southwest of this site. Heizer and Baumhoff additionally apply the site number of NY-3 to this site in their work, when actually...26NY3 is recorded as 38 0 Wagon Parts . Map 6. Civet Cat Canyon (26NY369) Site Plan. 39 * Contours not to scale - rendered for relief. ■T-.IKI

[Association between obesity and DNA methylation among the 7-16 year-old twins].

PubMed

Li, C X; Gao, Y; Gao, W J; Yu, C Q; Lyu, J; Lyu, R R; Duan, J L; Sun, Y; Guo, X H; Wang, S F; Zhou, B; Wang, G; Cao, W H; Li, L M

2018-04-10

Objective: On whole-genome scale, we tried to explore the correlation between obesity-related traits and DNA methylation sites, based on discordant monozygotic twin pairs. Methods: A total of 90 pairs of 6-17 year-old twins were recruited in Chaoyang district, Yanqing district and Fangshan district in Beijing in 2016. Information on twins was gathered through a self-designed questionnaire and results: from physical examination, including height, weight and waist circumference of the subjects under study. DNA methylation detection was chosen on the Illumina Human Methylation EPIC BeadChip. R 3.3.1 language was used to read the DNA methylation signal under quality control on samples and probes. Ebayes function of empirical Bayes paired moderated t -test was used to identify the differential methylated CpG sites (DMCs). VarFit function of empirical Bayes paired moderated Levene test was used to identify the differentially variables CpG sits (DVCs) in obese and normal groups. Results According to the obesity discordance criteria, we collected 23 pairs of twins (age range 7 to 16 years), including 12 male pairs. A total of 817 471 qualified CpG loci were included in the genome-wide correlation analysis. According to the significance level of FDR set as <0.05, no positive sites would meet this standard. When DMC CpG site cg05684382, with the smallest P value (1.26E-06) as on chromosome 12, the DVC CpG site cg26188191 with the smallest P value (6.44E-06) appeared in CMIP gene on chromosome 16. Conclusions: In this study, we analyzed the genome-wide DNA methylation and its correlation with obesity traits. After multiple testing corrections, no positive sites were found to have associated with obesity. However, results from the correlation analysis demonstrated sites cg05684382 (chr: 12) and cg26188191 (chr: 16) might have played a role in the development of obesity. This study provides a methodologic reference for the studies on discordance twins related problems.

Information on infantile colic on the World Wide Web.

PubMed

Bailey, Shana D; D'Auria, Jennifer P; Haushalter, Jamie P

2013-01-01

The purpose of this study was to explore and describe the type and quality of information on infantile colic that a parent might access on the World Wide Web. Two checklists were used to evaluate the quality indicators of 24 Web sites and the colic-specific content. Fifteen health information Web sites met more of the quality parameters than the nine commercial sites. Eight Web sites included information about colic and infant abuse, with six being health information sites. The colic-specific content on 24 Web sites reflected current issues and controversies; however, the completeness of the information in light of current evidence varied among the Web sites. Strategies to avoid complications of parental stress or infant abuse were not commonly found on the Web sites. Pediatric professionals must guide parents to reliable colic resources that also include emotional support and understanding of infant crying. A best evidence guideline for the United States would eliminate confusion and uncertainty about which colic therapies are safe and effective for parents and professionals. Copyright © 2013 National Association of Pediatric Nurse Practitioners. Published by Mosby, Inc. All rights reserved.

Repeat 24-hour recalls and locally developed food composition databases: a feasible method to estimate dietary adequacy in a multi-site preconception maternal nutrition RCT.

PubMed

Lander, Rebecca L; Hambidge, K Michael; Krebs, Nancy F; Westcott, Jamie E; Garces, Ana; Figueroa, Lester; Tejeda, Gabriela; Lokangaka, Adrien; Diba, Tshilenge S; Somannavar, Manjunath S; Honnayya, Ranjitha; Ali, Sumera A; Khan, Umber S; McClure, Elizabeth M; Thorsten, Vanessa R; Stolka, Kristen B

2017-01-01

Background : Our aim was to utilize a feasible quantitative methodology to estimate the dietary adequacy of >900 first-trimester pregnant women in poor rural areas of the Democratic Republic of the Congo, Guatemala, India and Pakistan. This paper outlines the dietary methods used. Methods : Local nutritionists were trained at the sites by the lead study nutritionist and received ongoing mentoring throughout the study. Training topics focused on the standardized conduct of repeat multiple-pass 24-hr dietary recalls, including interview techniques, estimation of portion sizes, and construction of a unique site-specific food composition database (FCDB). Each FCDB was based on 13 food groups and included values for moisture, energy, 20 nutrients (i.e. macro- and micronutrients), and phytate (an anti-nutrient). Nutrient values for individual foods or beverages were taken from recently developed FAO-supported regional food composition tables or the USDA national nutrient database. Appropriate adjustments for differences in moisture and application of nutrient retention and yield factors after cooking were applied, as needed. Generic recipes for mixed dishes consumed by the study population were compiled at each site, followed by calculation of a median recipe per 100 g. Each recipe's nutrient values were included in the FCDB. Final site FCDB checks were planned according to FAO/INFOODS guidelines. Discussion : This dietary strategy provides the opportunity to assess estimated mean group usual energy and nutrient intakes and estimated prevalence of the population 'at risk' of inadequate intakes in first-trimester pregnant women living in four low- and middle-income countries. While challenges and limitations exist, this methodology demonstrates the practical application of a quantitative dietary strategy for a large international multi-site nutrition trial, providing within- and between-site comparisons. Moreover, it provides an excellent opportunity for local capacity building and each site FCDB can be easily modified for additional research activities conducted in other populations living in the same area.

Acupoint injection of onabotulinumtoxin A for migraines.

PubMed

Hou, Min; Xie, Jun-Fan; Kong, Xiang-Pan; Zhang, Yi; Shao, Yu-Feng; Wang, Can; Ren, Wen-Ting; Cui, Guang-Fu; Xin, Le; Hou, Yi-Ping

2015-10-30

Onabotulinumtoxin A (BoNTA) has been reported to be effective in the therapy for migraines. Acupuncture has been used worldwide for the treatment of migraine attacks. Injection of a small amount of drug at acupuncture points is an innovation as compared to traditional acupuncture. The purpose of this study was to evaluate and compare the effectiveness of fixed (muscle)-site and acupoint-site injections of BoNTA for migraine therapy in a randomized, double-blinded, placebo-controlled clinical trial extending over four months. Subjects with both episodic and chronic migraines respectively received a placebo (n = 19) or BoNTA (2.5 U each site, 25 U per subject) injection at fixed-sites (n = 41) including occipitofrontalis, corrugator supercilii, temporalis and trapeziue, or at acupoint-sites (n = 42) including Yintang (EX-HN3), Taiyang (EX-HN5), Baihui (GV20), Shuaigu (GB8), Fengchi (GB20) and Tianzhu (BL10). The variations between baseline and BoNTA post-injection for four months were calculated monthly as outcome measures. BoNTA injections at fixed-sites and acupoint-sites significantly reduced the migraine attack frequency, intensity, duration and associated symptoms for four months compared with placebo (p < 0.01). The efficacy of BoNTA for migraines in the acupoint-site group (93% improvement) was more significant than that in the fixed-site group (85% improvement) (p < 0.01). BoNTA administration for migraines is effective, and at acupoint-sites shows more efficacy than at fixed-sites. Further blinded studies are necessary to establish the efficacy of a low dose toxin (25 U) introduced with this methodology in chronic and episodic migraines.

Acupoint Injection of Onabotulinumtoxin A for Migraines

PubMed Central

Hou, Min; Xie, Jun-Fan; Kong, Xiang-Pan; Zhang, Yi; Shao, Yu-Feng; Wang, Can; Ren, Wen-Ting; Cui, Guang-Fu; Xin, Le; Hou, Yi-Ping

2015-01-01

Onabotulinumtoxin A (BoNTA) has been reported to be effective in the therapy for migraines. Acupuncture has been used worldwide for the treatment of migraine attacks. Injection of a small amount of drug at acupuncture points is an innovation as compared to traditional acupuncture. The purpose of this study was to evaluate and compare the effectiveness of fixed (muscle)-site and acupoint-site injections of BoNTA for migraine therapy in a randomized, double-blinded, placebo-controlled clinical trial extending over four months. Subjects with both episodic and chronic migraines respectively received a placebo (n = 19) or BoNTA (2.5 U each site, 25 U per subject) injection at fixed-sites (n = 41) including occipitofrontalis, corrugator supercilii, temporalis and trapeziue, or at acupoint-sites (n = 42) including Yintang (EX-HN3), Taiyang (EX-HN5), Baihui (GV20), Shuaigu (GB8), Fengchi (GB20) and Tianzhu (BL10). The variations between baseline and BoNTA post-injection for four months were calculated monthly as outcome measures. BoNTA injections at fixed-sites and acupoint-sites significantly reduced the migraine attack frequency, intensity, duration and associated symptoms for four months compared with placebo (p < 0.01). The efficacy of BoNTA for migraines in the acupoint-site group (93% improvement) was more significant than that in the fixed-site group (85% improvement) (p < 0.01). BoNTA administration for migraines is effective, and at acupoint-sites shows more efficacy than at fixed-sites. Further blinded studies are necessary to establish the efficacy of a low dose toxin (25 U) introduced with this methodology in chronic and episodic migraines. PMID:26529014

Analysis strategies for longitudinal attachment loss data.

PubMed

Beck, J D; Elter, J R

2000-02-01

The purpose of this invited review is to describe and discuss methods currently in use to quantify the progression of attachment loss in epidemiological studies of periodontal disease, and to make recommendations for specific analytic methods based upon the particular design of the study and structure of the data. The review concentrates on the definition of incident attachment loss (ALOSS) and its component parts; measurement issues including thresholds and regression to the mean; methods of accounting for longitudinal change, including changes in means, changes in proportions of affected sites, incidence density, the effect of tooth loss and reversals, and repeated events; statistical models of longitudinal change, including the incorporation of the time element, use of linear, logistic or Poisson regression or survival analysis, and statistical tests; site vs person level of analysis, including statistical adjustment for correlated data; the strengths and limitations of ALOSS data. Examples from the Piedmont 65+ Dental Study are used to illustrate specific concepts. We conclude that incidence density is the preferred methodology to use for periodontal studies with more than one period of follow-up and that the use of studies not employing methods for dealing with complex samples, correlated data, and repeated measures does not take advantage of our current understanding of the site- and person-level variables important in periodontal disease and may generate biased results.

Is There a Role for Social Networking Sites in Education?

NASA Astrophysics Data System (ADS)

Santos, Ieda M.; Hammond, Michael; Durli, Zenilde; Chou, Shiao-Yuh

Social networking sites such as Facebook and MySpace have become popular among millions of users including students of all ages. There are ongoing discussions over the potential of these sites to support teaching and learning, particularly to complement traditional or online classroom activities. This paper explores whether social networking have a place in teaching and learning by investigating how students use these sites and whether they find opportunities to discuss study related activities with their peers. Two small scale studies were carried out in a face-to-face undergraduate course in Singapore and students enrolled in a face-to-face Master’s programme in Brazil. Data were collected using surveys and interviews; findings were mixed. Many of the Brazilian students used social networking sites to both socialize and discuss their studies while the Singaporean students used such sites for social interactions only. The paper discusses these differences and offers suggestions for further research.

Method of injection of onabotulinumtoxinA for chronic migraine: a safe, well-tolerated, and effective treatment paradigm based on the PREEMPT clinical program.

PubMed

Blumenfeld, Andrew; Silberstein, Stephen D; Dodick, David W; Aurora, Sheena K; Turkel, Catherine C; Binder, William J

2010-10-01

Chronic migraine (CM) is a prevalent and disabling neurological disorder. Few prophylactic treatments for CM have been investigated. OnabotulinumtoxinA, which inhibits the release of nociceptive mediators, such as glutamate, substance P, and calcitonin gene-related peptide, has been evaluated in randomized, placebo-controlled studies for the preventive treatment of a variety of headache disorders, including CM. These studies have yielded insight into appropriate patient selection, injection sites, dosages, and technique. Initial approaches used a set of fixed sites for the pericranial injections. However, the treatment approach evolved to include other sites that corresponded to the location of pain and tenderness in the individual patient in addition to the fixed sites. The Phase III REsearch Evaluating Migraine Prophylaxis Therapy (PREEMPT) injection paradigm uses both fixed and follow-the-pain sites, with additional specific follow-the-pain sites considered depending on individual symptoms. The PREEMPT paradigm for injecting onabotulinumtoxinA has been shown to be safe, well-tolerated, and effective in well-designed, controlled clinical trials and is the evidence-based approach recommended to optimize clinical outcomes for patients with CM. © 2010 American Headache Society.

Snake River Plain FORGE Site Characterization Data

DOE Data Explorer

Moos, Danial; Barton, Colleen A.

2016-04-18

The site characterization data used to develop the conceptual geologic model for the Snake River Plain site in Idaho, as part of phase 1 of the Frontier Observatory for Research in Geothermal Energy (FORGE) initiative. This collection includes data on seismic events, groundwater, geomechanical models, gravity surveys, magnetics, resistivity, magnetotellurics (MT), rock physics, stress, the geologic setting, and supporting documentation, including several papers. Also included are 3D models (Petrel and Jewelsuite) of the proposed site. Data for wells INEL-1, WO-2, and USGS-142 have been included as links to separate data collections. These data have been assembled by the Snake River Geothermal Consortium (SRGC), a team of collaborators that includes members from national laboratories, universities, industry, and federal agencies, lead by the Idaho National Laboratory (INL). Other contributors include the National Renewable Energy Laboratory (NREL), Lawrence Livermore National Laboratory (LLNL), the Center for Advanced Energy Studies (CEAS), the University of Idaho, Idaho State University, Boise State University, University of Wyoming, University of Oklahoma, Energy and Geoscience Institute-University of Utah, US Geothermal, Baker Hughes Campbell Scientific Inc., Chena Power, US Geological Survey (USGS), Idaho Department of Water Resources, Idaho Geological Survey, and Mink GeoHydro.

Clear-water abutment and contraction scour in the Coastal Plain and Piedmont Provinces of South Carolina, 1996-99

USGS Publications Warehouse

Benedict, Stephen T.

2016-01-01

Data from this study have been compiled into a database that includes photographs, figures, observed scour depths, theoretical scour depths, limited basin characteristics, limited soil data, and theoretical hydraulic data. The database can be used to compare studied sites with unstudied sites to assess the potential for scour at the unstudied sites. In addition, the database can be used to assess the performance of various theoretical methods for predicting clear-water abutment and contraction scour.

Using Carbohydrate Interaction Assays to Reveal Novel Binding Sites in Carbohydrate Active Enzymes.

PubMed

Cockburn, Darrell; Wilkens, Casper; Dilokpimol, Adiphol; Nakai, Hiroyuki; Lewińska, Anna; Abou Hachem, Maher; Svensson, Birte

2016-01-01

Carbohydrate active enzymes often contain auxiliary binding sites located either on independent domains termed carbohydrate binding modules (CBMs) or as so-called surface binding sites (SBSs) on the catalytic module at a certain distance from the active site. The SBSs are usually critical for the activity of their cognate enzyme, though they are not readily detected in the sequence of a protein, but normally require a crystal structure of a complex for their identification. A variety of methods, including affinity electrophoresis (AE), insoluble polysaccharide pulldown (IPP) and surface plasmon resonance (SPR) have been used to study auxiliary binding sites. These techniques are complementary as AE allows monitoring of binding to soluble polysaccharides, IPP to insoluble polysaccharides and SPR to oligosaccharides. Here we show that these methods are useful not only for analyzing known binding sites, but also for identifying new ones, even without structural data available. We further verify the chosen assays discriminate between known SBS/CBM containing enzymes and negative controls. Altogether 35 enzymes are screened for the presence of SBSs or CBMs and several novel binding sites are identified, including the first SBS ever reported in a cellulase. This work demonstrates that combinations of these methods can be used as a part of routine enzyme characterization to identify new binding sites and advance the study of SBSs and CBMs, allowing them to be detected in the absence of structural data.

Using Carbohydrate Interaction Assays to Reveal Novel Binding Sites in Carbohydrate Active Enzymes

PubMed Central

Wilkens, Casper; Dilokpimol, Adiphol; Nakai, Hiroyuki; Lewińska, Anna; Abou Hachem, Maher; Svensson, Birte

2016-01-01

Carbohydrate active enzymes often contain auxiliary binding sites located either on independent domains termed carbohydrate binding modules (CBMs) or as so-called surface binding sites (SBSs) on the catalytic module at a certain distance from the active site. The SBSs are usually critical for the activity of their cognate enzyme, though they are not readily detected in the sequence of a protein, but normally require a crystal structure of a complex for their identification. A variety of methods, including affinity electrophoresis (AE), insoluble polysaccharide pulldown (IPP) and surface plasmon resonance (SPR) have been used to study auxiliary binding sites. These techniques are complementary as AE allows monitoring of binding to soluble polysaccharides, IPP to insoluble polysaccharides and SPR to oligosaccharides. Here we show that these methods are useful not only for analyzing known binding sites, but also for identifying new ones, even without structural data available. We further verify the chosen assays discriminate between known SBS/CBM containing enzymes and negative controls. Altogether 35 enzymes are screened for the presence of SBSs or CBMs and several novel binding sites are identified, including the first SBS ever reported in a cellulase. This work demonstrates that combinations of these methods can be used as a part of routine enzyme characterization to identify new binding sites and advance the study of SBSs and CBMs, allowing them to be detected in the absence of structural data. PMID:27504624

Hydrologic, water-quality, and meteorologic data from selected sites in the Upper Catawba River Basin, North Carolina, January 1993 through March 1994

USGS Publications Warehouse

Jaynes, M.L.

1994-01-01

Hydrologic, water-quality, and meteorologic data were collected from January 1993 through March 1994 as part of a water-quality investigation of the Upper Catawba River Basin, North Carolina. Specific objectives of the investigation were to characterize the water quality of Rhodhiss Lake, Lake Hickory, and three tributary streams, and to calibrate hydrodynamic water-quality models for the two reservoirs. Sampling locations included 11 sites in Rhodhiss Lake, 14 sites in Lake Hickory, and 3 tributary sites. Tributary sites were located at Lower Creek upstream from Rhodhiss Lake and at Upper Little River and Middle Little River upstream from Lake Hickory. During 21 sampling visits, specific conductance, pH, water temperature, dissolved-oxygen concentration, and water transparency were measured at all sampling locations. Water samples were collected for analysis of biochemical oxygen demand, fecal coliform bacteria, hardness, alkalinity, total and volatile suspended solids, suspended sediment, nutrients, total organic carbon, chlorophyll, iron, calcium, and magnesium from three sites in each reservoir and from the three tributary sites. Chemical and particle-size analyses of bottom material from Rhodhiss Lake and Lake Hickory were performed once during the study. At selected locations, automated instruments recorded water level, streamflow, water temperature, solar radiation, and air temperature at 15-minute intervals throughout the study. Hydrologic data presented in the report include monthly water-level statistics and daily mean values of discharge. Diagrams, tables, and statistical summaries of water-quality data are provided. Meteorologic data in the report include monthly precipitation, and daily mean values of solar radiation and air temperature.

Effectiveness of a bundled intervention of decolonization and prophylaxis to decrease Gram positive surgical site infections after cardiac or orthopedic surgery: systematic review and meta-analysis.

PubMed

Schweizer, Marin; Perencevich, Eli; McDanel, Jennifer; Carson, Jennifer; Formanek, Michelle; Hafner, Joanne; Braun, Barbara; Herwaldt, Loreen

2013-06-13

To evaluate studies assessing the effectiveness of a bundle of nasal decolonization and glycopeptide prophylaxis for preventing surgical site infections caused by Gram positive bacteria among patients undergoing cardiac operations or total joint replacement procedures. Systematic review and meta-analysis. PubMed (1995 to 2011), the Cochrane database of systematic reviews, CINAHL, Embase, and clinicaltrials.gov were searched to identify relevant studies. Pertinent journals and conference abstracts were hand searched. Study authors were contacted if more data were needed. Randomized controlled trials, quasi-experimental studies, and cohort studies that assessed nasal decolonization or glycopeptide prophylaxis, or both, for preventing Gram positive surgical site infections compared with standard care. Patients undergoing cardiac operations or total joint replacement procedures. DATA EXTRACTION AND STUDY APPRAISAL: Two authors independently extracted data from each paper and a random effects model was used to obtain summary estimates. Risk of bias was assessed using the Downs and Black or the Cochrane scales. Heterogeneity was assessed using the Cochran Q and I(2) statistics. 39 studies were included. Pooled effects of 17 studies showed that nasal decolonization had a significantly protective effect against surgical site infections associated with Staphylococcus aureus (pooled relative risk 0.39, 95% confidence interval 0.31 to 0.50) when all patients underwent decolonization (0.40, 0.29 to 0.55) and when only S aureus carriers underwent decolonization (0.36, 0.22 to 0.57). Pooled effects of 15 prophylaxis studies showed that glycopeptide prophylaxis was significantly protective against surgical site infections related to methicillin (meticillin) resistant S aureus (MRSA) compared with prophylaxis using β lactam antibiotics (0.40, 0.20 to 0.80), and a non-significant risk factor for methicillin susceptible S aureus infections (1.47, 0.91 to 2.38). Seven studies assessed a bundle including decolonization and glycopeptide prophylaxis for only patients colonized with MRSA and found a significantly protective effect against surgical site infections with Gram positive bacteria (0.41, 0.30 to 0.56). Surgical programs that implement a bundled intervention including both nasal decolonization and glycopeptide prophylaxis for MRSA carriers may decrease rates of surgical site infections caused by S aureus or other Gram positive bacteria.

Understanding the physical and chemical nature of the warfarin drug binding site in human serum albumin: experimental and theoretical studies.

PubMed

Abou-Zied, Osama K

2015-01-01

Human serum albumin (HSA) is one of the major carrier proteins in the body and constitutes approximately half of the protein found in blood plasma. It plays an important role in lipid metabolism, and its ability to reversibly bind a large variety of pharmaceutical compounds makes it a crucial determinant of drug pharmacokinetics and pharmacodynamics. This review deals with one of the protein's major binding sites "Sudlow I" which includes a binding pocket for the drug warfarin (WAR). The binding nature of this important site can be characterized by measuring the spectroscopic changes when a ligand is bound. Using several drugs, including WAR, and other drug-like molecules as ligands, the results emphasize the nature of Sudlow I as a flexible binding site, capable of binding a variety of ligands by adapting its binding pockets. The high affinity of the WAR pocket for binding versatile molecular structures stems from the flexibility of the amino acids forming the pocket. The binding site is shown to have an ionization ability which is important to consider when using drugs that are known to bind in Sudlow I. Several studies point to the important role of water molecules trapped inside the binding site in molecular recognition and ligand binding. Water inside the protein's cavity is crucial in maintaining the balance between the hydrophobic and hydrophilic nature of the binding site. Upon the unfolding and refolding of HSA, more water molecules are trapped inside the binding site which cause some swelling that prevents a full recovery from the denatured state. Better understanding of the mechanism of binding in macromolecules such as HSA and other proteins can be achieved by combining experimental and theoretical studies which produce significant synergies in studying complex biochemical phenomena.

Modeling the impact of hydraulic redistribution on the carbon flux and storages using CLM4.5 at four AmeriFlux Sites

NASA Astrophysics Data System (ADS)

Fu, C.; Wang, G.; Cardon, Z. G.

2015-12-01

Effects of hydraulic redistribution (HR) on the hydrological cycle and ecosystem dynamics have been demonstrated in the field, but few modeling studies have compared HR's influences on the carbon cycle in different ecosystems and climate regions. The soil moisture changes associated with HR could influence plant carbon gain via two mechanisms: (1) improved plant water status supporting stomatal opening, and/or (2) enhanced nutrient availability to plants caused by enhanced soil microbial activity. In this study, using a modified version of the Community Land Model with Century-based soil carbon pool kinetics that includes the "Ryel et al. 2002" scheme for hydraulic redistribution (HR), the influence of HR on the carbon flux and storage is investigated at four Ameriflux sites where HR was detected from soil moisture measurements. The study sites include a Douglas-fir site (US-Wrc) in Washington State with a mediterranean climate, a savanna site (US-SRM) in Arizona with a semi-arid climate, an oak/pine forest site (US-SCf) in Southern California with a mediterranean climate, and an evergreen broadleaf forest site (BR-Sa1) with tropical monsoon climate. Simulations revealed that HR tended to enhance plant growth at all four sites, and incorporating HR into CLM4.5 reduces the temporal fluctuation of soil carbon storage at all four sites. Simulations with HR can capture the net carbon exchange between ecosystem and the atmosphere (NEE) at the US-Wrc, US-SRM, and BR-Sa1 sites over the annual cycle. Incorporation of HR into CLM4.5 clearly improved the weekly and sub-daily NEE simulation during dry periods at US-SCf and BR-Sa1 site. HR-induced increase in Net Primary Productivity (NPP) at the US-Wrc and US-SRM sites was driven approximately equally by the two distinct mechanisms we investigated: increased stomatal conductance and increased nutrient availability to plants.

78 FR 16479 - Revised Notice of Intent To Prepare a joint Environmental Impact Statement/Environmental Impact...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-15

... has expanded the study area to include additional potential soil borrow sites. Material from these... soil borrow sites are located to the east and west of southern Jefferson Blvd.; adjacent to the...

A Method to Recognize Anatomical Site and Image Acquisition View in X-ray Images.

PubMed

Chang, Xiao; Mazur, Thomas; Li, H Harold; Yang, Deshan

2017-12-01

A method was developed to recognize anatomical site and image acquisition view automatically in 2D X-ray images that are used in image-guided radiation therapy. The purpose is to enable site and view dependent automation and optimization in the image processing tasks including 2D-2D image registration, 2D image contrast enhancement, and independent treatment site confirmation. The X-ray images for 180 patients of six disease sites (the brain, head-neck, breast, lung, abdomen, and pelvis) were included in this study with 30 patients each site and two images of orthogonal views each patient. A hierarchical multiclass recognition model was developed to recognize general site first and then specific site. Each node of the hierarchical model recognized the images using a feature extraction step based on principal component analysis followed by a binary classification step based on support vector machine. Given two images in known orthogonal views, the site recognition model achieved a 99% average F1 score across the six sites. If the views were unknown in the images, the average F1 score was 97%. If only one image was taken either with or without view information, the average F1 score was 94%. The accuracy of the site-specific view recognition models was 100%.

Drainage areas of New York streams, by river basins; a stream gazetteer; Part 1, Data compiled as of October 1980

USGS Publications Warehouse

Wagner, L.A.

1982-01-01

Hydrologic studies concerned with surface water require geographic data of several types, among which are stream length and size of drainage area from which runoff is contributed. This gazetteer presents all drainage-area data on New York streams that were available as of October 1980. The information is grouped by river basin, and each section consists of two lists. The first gives sites alphabetically by stream name and includes the body of water to which the stream is tributary, county in which the site is located, drainage area above the mouth, coordinates of the topographic quadrangle on the State index map , and the Geological Survey site number. The second list presents site information by U.S. Geological Survey site number (downstream order along the main stream) and includes drainage area, distance of measurement site above the mouth, and location by latitude and longitude. Data were compiled from published and unpublished sources, all of which are available for inspection at the U.S. Geological Survey in Albany, N.Y. Also included are updated values on several river basins that have been redelineated and whose drainage areas have been recomputed and retabulated since 1977. (USGS)

Associations between work-related musculoskeletal disorders, quality of life, and workplace stress in physical therapists

PubMed Central

BAE, Young-Hyeon; MIN, Kyoung Sam

2016-01-01

This study was performed to determine the associations between work-related musculoskeletal disorders (WMSDs), quality of life (QoL), and workplace stress among physical therapists (PTs) in South Korea. Self-reporting questionnaires were given to 855 PTs. Variables examined included general characteristics, WMSDs, QoL, and workplace stress. Of the 788 PTs who responded, 745 (94.5%) reported WMSDs affecting at least one body site. The most affected WMSDs site was the shoulder (23.3%), and the most reported number of body sites affected by WMSDs was one (50.9%). QoL was significantly improved (p<0.05) among PTs over 39 years old, who had 10–15 years of professional experience, worked in general/university hospitals, and had only one site affected by WMSDs. Factors influencing QoL included number of body sites affected by WMSDs, presence/absence of WMSDs, working venues, workplace stress, and age. Factors affecting workplace stress included number of body sites affected by WMSDs, QoL, work hours, and gender. The results showed a high prevalence of WMSDs among PTs in South Korea, and this negatively affected both QoL and workplace stress. PMID:26860785

Synthesis of information on the effects of noise and disturbance on major haulout concentrations of Bering Sea pinnipeds. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, S.R.; Burns, J.J.; Malme, C.I.

1989-02-17

The study investigated the use of terrestrial haulout sites in the eastern Bering Sea by four species of pennipeds, northern fur seal, northern sea lion, harbor seal and pacific walrus. Historical information on the use of each site was summarized. Available information on the effects of airborne and waterborne noise, and human disturbance (from stationary and moving sources) was reviewed. The authors also conducted a detailed analysis of the acoustic environment of eight haulout sites that were representative of others used by each of the four species studied. The analyses included investigations of (1) characteristics airborne and underwater ambient noise,more » (2) characteristics of industrial noise sources, including aircraft, small boats, fishing trawlers and commercial cargo traffic, and (3) sound transmission loss in air, water, and through the air-water surface. As a means to evaluate the potential vulnerability of each haulout site to noise and disturbance, a quantitative rating system (IPSI) whereby an index of sensitivity was assigned to each site.« less

Risk of port-site metastases in pelvic cancers after robotic surgery.

PubMed

Seror, J; Bats, A-S; Bensaïd, C; Douay-Hauser, N; Ngo, C; Lécuru, F

2015-04-01

To assess the risk of occurrence of port-site metastases after robotic surgery for pelvic cancer. Retrospective study from June 2007 to March 2013 of patients with gynecologic cancer who underwent robot-assisted surgery. We collected preoperative data, including characteristics of patients and FIGO stage, intraoperative data (surgery performed, number of ports), and postoperative data (occurrence of metastases, occurrence of port-site metastases). 115 patients were included in the study: 61 with endometrial cancer, 50 with cervical cancer and 4 with ovarian cancer. The surgical procedures performed were: hysterectomy with bilateral salpingo-oophorectomy, radical hysterectomy, pelvic lymphadenectomy, para-aortic lymphadenectomy and omentectomy. All surgical procedures required the introduction of 4 ports, 3 for the robot and 1 for the assistant. With a mean follow-up of 504.4 days (507.7 days for endometrial cancer, 479.5 days for cervical cancer, and 511.3 for ovarian cancer), we observed 9 recurrences but no port-site metastasis. No port-site metastasis has occurred in our series. However, larger, prospective and randomized works are needed to formally conclude. Copyright © 2015 Elsevier Ltd. All rights reserved.

Investigation of anatomical anomalies in Hanford Site mule deer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tiller, B.L.; Cadwell, L.L.; Poston, T.M.

Rocky Mountain mule deer (Odocoileus hemionus hemionus), common residents of the Hanford Site, are an important part of the shrub-steppe ecosystem as well as being valued for aesthetics and hunting. Because mule deer have been protected from hunting on the Site for 50 years, the herd has developed unique population characteristics, including a large number of old animals and males with either large or atypically developed antlers, in contrast to other herds in the semi-arid regions of the Northwest. Hanford Site mule deer have been studied since 1991 because of the herd`s unique nature and high degree of public interest.more » A special study of the mule deer herd was initiated in 1993 after observations were made of a relatively large number of male deer with atypical, velvet-covered antlers. This report specifically describes our analyses of adult male deer found on the Site with atypical antlers. The report includes estimates of population densities and composition; home ranges, habitat uses, and dietary habits; natural and human-induced causes of mortality; and the herd`s overall health and reproductive status.« less

Risk of adverse birth outcomes in populations living near landfill sites

PubMed Central

Elliott, Paul; Briggs, David; Morris, Sara; de Hoogh, Cornelis; Hurt, Christopher; Jensen, Tina Kold; Maitland, Ian; Richardson, Sylvia; Wakefield, Jon; Jarup, Lars

2001-01-01

Objective To investigate the risk of adverse birth outcomes associated with residence near landfill sites in Great Britain. Design Geographical study of risks of adverse birth outcomes in populations living within 2 km of 9565 landfill sites operational at some time between 1982 and 1997 (from a total of 19 196 sites) compared with those living further away. Setting Great Britain. Subjects Over 8.2 million live births, 43 471 stillbirths, and 124 597 congenital anomalies (including terminations). Main outcome measures All congenital anomalies combined, some specific anomalies, and prevalence of low and very low birth weight (<2500 g and <1500 g). Results For all anomalies combined, relative risk of residence near landfill sites (all waste types) was 0.92 (99% confidence interval 0.907 to 0.923) unadjusted, and 1.01 (1.005 to 1.023) adjusted for confounders. Adjusted risks were 1.05 (1.01 to 1.10) for neural tube defects, 0.96 (0.93 to 0.99) for cardiovascular defects, 1.07 (1.04 to 1.10) for hypospadias and epispadias (with no excess of surgical correction), 1.08 (1.01 to 1.15) for abdominal wall defects, 1.19 (1.05 to 1.34) for surgical correction of gastroschisis and exomphalos, and 1.05 (1.047 to 1.055) and 1.04 (1.03 to 1.05) for low and very low birth weight respectively. There was no excess risk of stillbirth. Findings for special (hazardous) waste sites did not differ systematically from those for non-special sites. For some specific anomalies, higher risks were found in the period before opening compared with after opening of a landfill site, especially hospital admissions for abdominal wall defects. Conclusions We found small excess risks of congenital anomalies and low and very low birth weight in populations living near landfill sites. No causal mechanisms are available to explain these findings, and alternative explanations include data artefacts and residual confounding. Further studies are needed to help differentiate between the various possibilities. What is already known on this topicVarious studies have found excess risks of certain congenital anomalies and low birth weight near landfill sitesRisks up to two to three times higher have been reportedThese studies have been difficult to interpret because of problems of exposure classification, small sample size, confounding, and reporting biasWhat this study addsSome 80% of the British population lives within 2 km of known landfill sites in Great BritainBy including all landfill sites in the country, we avoided the problem of selective reporting, and maximised statistical powerAlthough we found excess risks of congenital anomalies and low birth weight near landfill sites in Great Britain, they were smaller than in some other studiesFurther work is needed to differentiate potential data artefacts and confounding effects from possible causal associations with landfill PMID:11509424

A Systems Study to Determine the Attractiveness of Solar System Bodies and Sites for Eventual Human Exploration

NASA Technical Reports Server (NTRS)

Andringa, Jason M.; Gray, Andrew A.

2005-01-01

A pre-phase A idea-generation team at the Jet Propulsion Laboratory (JPL), has conducted a study to rank all locations in the solar system based on attractiveness for human exploration. The process used to perform the study was composed of the following primary steps: determination of criteria (including value, cost, and risk criteria) upon which to rate sites in the solar system; weighting of the criteria based upon importance to eventual human exploration; selection of sites to consider and assignment of team members to the task of advocating the benefits of particular sites; rating the sites in both the short- and longterm based on team member presentations and team discussions; compilation of a score based on criteria weights and individual ratings. Finally a comparison of the total scores of different sites was completed to determine a ranking of all the bodies and sites in the solar system. Sensitivity analysis was also performed to determine how weightings affect the rankings.

Early-life skin microbiota in hospitalized preterm and full-term infants.

PubMed

Younge, Noelle E; Araújo-Pérez, Félix; Brandon, Debra; Seed, Patrick C

2018-05-31

The infant skin microbiota may serve as a reservoir of bacteria that contribute to neonatal infections and stimulate local and systemic immune development. The objectives of our study were to characterize the skin microbiota of preterm and full-term infants during their birth hospitalization and describe its relationship to the microbiota of other body sites and the hospital environment. We conducted a cross-sectional study of 129 infants, including 40 preterm and 89 full-term infants. Samples were collected from five sites: the forehead and posterior auricular scalp (skin upper body); the periumbilical region, inguinal folds, and upper thighs (skin lower body); the oral cavity; the infant's immediate environment; and stool. Staphylococcus, Streptococcus, Enterococcus, and enteric Gram-negative bacteria including Escherichia and Enterobacter dominated the skin microbiota. The preterm infant microbiota at multiple sites had lower alpha diversity and greater enrichment with Staphylococcus and Escherichia than the microbiota of comparable sites in full-term infants. The community structure was highly variable among individuals but differed significantly by body site, postnatal age, and gestational age. Source tracking indicated that each body site both contributed to and received microbiota from other body sites and the hospital environment. The skin microbiota of preterm and full-term infants varied across individuals, by body site, and by the infant's developmental stage. The skin harbored many organisms that are common pathogens in hospitalized infants. Bacterial source tracking suggests that microbiota are commonly exchanged across body sites and the hospital environment as microbial communities mature in infancy.

Riparian buffer design guidelines for water quality and wildlife habitat functions on agricultural landscapes in the Intermountain West: Case Study

Treesearch

Craig W. Johnson; Susan Buffler

2008-01-01

This hypothetical case study illustrates how the riparian buffer planning protocol described in the RB handbook is used to plan a buffer for both water quality and wildlife conservation on a specific project site. The case study site includes riparian buffer characteristics typical of the study area-variable topography and soils, flood plain wetlands, seeps, springs,...

Utility of rapid on-site cytologic evaluation during endobronchial ultrasound with a guide sheath for peripheral pulmonary lesions.

PubMed

Izumo, Takehiro; Matsumoto, Yuji; Sasada, Shinji; Chavez, Christine; Nakai, Toshiyuki; Tsuchida, Takaaki

2017-03-01

The utility of rapid on-site evaluation during endobronchial ultrasound with a guide sheath for peripheral pulmonary lesions is unclear. The aim of this study was to evaluate the role of rapid on-site evaluation during endobronchial ultrasound with a guide sheath for peripheral pulmonary lesions. Consecutive patients who underwent endobronchial ultrasound with a guide sheath for the diagnosis of peripheral pulmonary lesions at our hospital between September 2012 and July 2014 were included in this retrospective study. Cytology slides were air-dried, and modified Giemsa (Diff-Quik) staining was used for rapid on-site evaluation. Additional smears were prepared for Papanicolaou staining and tissue samples were placed in formalin for histologic evaluation. The results of rapid on-site evaluation were compared with the final diagnoses of endobronchial ultrasound with a guide sheath. A total of 718 cases were included in the study population. The sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of rapid on-site evaluation during endobronchial ultrasound with a guide sheath for peripheral pulmonary lesions was 88.6%, 65.9%, 81.2%, 77.7% and 80.1%, respectively. There were no procedure-related deaths. Rapid on-site evaluation during endobronchial ultrasound with a guide sheath had high sensitivity for peripheral pulmonary lesions. When carrying out rapid on-site evaluation of transbronchial biopsy samples from peripheral pulmonary lesions, careful interpretation and clinical correlation are necessary. © The Author 2016. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

76 FR 5833 - Polaris Industries, Including On-Site Leased Workers From Westaff, Supply Technologies, Aerotek...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-02

..., Including On-Site Leased Workers From Westaff, Supply Technologies, Aerotek, and Securitas Security Services..., including on-site leased workers from Westaff, Supply Technologies, Aerotek and Securitas Security Services... was amended on December 6, 2010 to include on- site leased workers from Supply Technologies. The...

Work Site-Based Environmental Interventions to Reduce Sedentary Behavior: A Systematic Review.

PubMed

Hutcheson, Amanda K; Piazza, Andrew J; Knowlden, Adam P

2018-01-01

The purpose of this investigation was to systematically review work site-based, environmental interventions to reduce sedentary behavior following preferred reporting items for systematic reviews and meta-analyses guidelines. Data were extracted from Medical Literature Analysis and Retrieval System Online, Cochrane Central Register of Controlled Trials, and Web of Science between January 2005 and December 2015. Inclusion criteria were work site interventions, published in peer-reviewed journals, employing environmental modalities, targeting sedentary behavior, and using any quantitative design. Exclusion criteria were noninterventions and non-English publications. Data extracted included study design, population, intervention dosage, intervention activities, evaluation measures, and intervention effects. Data were tabulated quantitatively and synthesized qualitatively. A total of 15 articles were identified for review and 14 reported statistically significant decreases in sedentary behavior. The majority of studies employed a randomized controlled trial design (n = 7), used inclinometers to measure sedentary behavior (n = 9), recruited predominantly female samples (n = 15), and utilized sit-to-stand desks as the primary intervention modality (n = 10). The mean methodological quality score was 6.2 out of 10. Environmental work site interventions to reduce sedentary behavior show promise because work sites often have more control over environmental factors. Limitations of this intervention stream include inconsistent measurement of sedentary behavior, absence of theoretical frameworks to guide program development, and absence of long-term evaluation. Future studies should include clear reporting of intervention strategies and explicit operationalization of theoretical constructs.

Clinical implications of single- versus multiple-site keloid disorder: a retrospective study in an Asian population.

PubMed

Park, Tae Hwan; Park, Ji Hae; Tirgan, Michael H; Halim, Ahmad Sukari; Chang, Choong Hyun

2015-02-01

There is strong evidence of genetic susceptibility in individuals with keloid disorder. The purpose of this cross-sectional study was to determine the clinical relevance of our proposed variables on the multiplicity of keloids by further investigating the presence of other keloids and a family history. This was a retrospective review, using institutional review board-approved questionnaires, of patients with keloids who were seen at Kangbuk Samsung Hospital between December 2002 and February 2010. Eight hundred sixty-eight patients were included in our study. Comparisons between the 2 groups were made using Mann-Whitney tests for continuous variables and χ2 tests for categorical variables. In our patient group, younger age of onset and the presence of family history were significantly associated with the occurrence of keloids at multiple sites. The locations of extra-auricular keloids, in order of frequency, included the shoulder; anterior chest, including the breasts; deltoid; trunk and pubic area; upper extremities; lower extremities; and other sites. As compared to secondary keloids, primary keloids were significantly associated with both a lower degree of recurrence and the presence of other keloids. The presence or absence of family history was significantly associated with the presence or absence of other keloids and primary or secondary keloids. Keloid disorder is one of the most frustrating problems in wound healing and advances in our understanding of the differences of occurrence at a single site versus multiple sites might help in understanding pathogenesis and improving treatment.

Landfill site selection using combination of GIS and fuzzy AHP, a case study: Iranshahr, Iran.

PubMed

Torabi-Kaveh, M; Babazadeh, R; Mohammadi, S D; Zaresefat, M

2016-03-09

One of the most important recent challenges in solid waste management throughout the world is site selection of sanitary landfill. Commonly, because of simultaneous effects of social, environmental, and technical parameters on suitability of a landfill site, landfill site selection is a complex process and depends on several criteria and regulations. This study develops a multi-criteria decision analysis (MCDA) process, which combines geographic information system (GIS) analysis with a fuzzy analytical hierarchy process (FAHP), to determine suitable sites for landfill construction in Iranshahr County, Iran. The GIS was used to calculate and classify selected criteria and FAHP was used to assess the criteria weights based on their effectiveness on selection of potential landfill sites. Finally, a suitability map was prepared by overlay analyses and suitable areas were identified. Four suitability classes within the study area were separated, including high, medium, low, and very low suitability areas, which represented 18%, 15%, 55%, and 12% of the study area, respectively. © The Author(s) 2016.

Spectral study of suggested Apollo sites. [proposals for financial support and the electronic spectra of pyroxenes

NASA Technical Reports Server (NTRS)

Mccord, T. B.

1973-01-01

The spectrophotometry (0.3 to 1.1 microns) of visited and proposed Apollo landing sites is presented along with proposals for financial support of the spectral study. The electronic spectra of pyroxenes is investigated along with an interpretation of telescopic spectral reflectivity curves of the moon. Reprints of published articles related to these studies are included.

PS2-06: Best Practices for Advancing Multi-site Chart Abstraction Research

PubMed Central

Blick, Noelle; Cole, Deanna; King, Colleen; Riordan, Rick; Von Worley, Ann; Yarbro, Patty

2012-01-01

Background/Aims Multi-site chart abstraction studies are becoming increasingly common within the HMORN. Differences in systems among HMORN sites can pose significant obstacles to the success of these studies. It is therefore crucial to standardize abstraction activities by following best practices for multi-site chart abstraction, as consistency of processes across sites will increase efficiencies and enhance data quality. Methods Over the past few months the authors have been meeting to identify obstacles to multi-site chart abstraction and to address ways in which multi-site chart abstraction processes can be systemized and standardized. The aim of this workgroup is to create a best practice guide for multi-site chart abstraction studies. Focus areas include: abstractor training, format for chart abstraction (database, paper, etc), data quality, redaction, mechanism for transferring data, site specific access to medical records, IRB/HIPAA concerns, and budgetary issues. Results The results of the workgroup’s efforts (the best practice guide) will be presented by a panel of experts at the 2012 HMORN conference. The presentation format will also focus on discussion among attendees to elicit further input and to identify areas that need to be further addressed. Subsequently, the best practice guide will be posted on the HMORN website. Discussion The best practice guide for multi-site chart abstraction studies will establish sound guidelines and serve as an aid to researchers embarking on multi-site chart abstraction studies. Efficiencies and data quality will be further enhanced with standardized multi-site chart abstraction practices.

Optimized probability sampling of study sites to improve generalizability in a multisite intervention trial.

PubMed

Kraschnewski, Jennifer L; Keyserling, Thomas C; Bangdiwala, Shrikant I; Gizlice, Ziya; Garcia, Beverly A; Johnston, Larry F; Gustafson, Alison; Petrovic, Lindsay; Glasgow, Russell E; Samuel-Hodge, Carmen D

2010-01-01

Studies of type 2 translation, the adaption of evidence-based interventions to real-world settings, should include representative study sites and staff to improve external validity. Sites for such studies are, however, often selected by convenience sampling, which limits generalizability. We used an optimized probability sampling protocol to select an unbiased, representative sample of study sites to prepare for a randomized trial of a weight loss intervention. We invited North Carolina health departments within 200 miles of the research center to participate (N = 81). Of the 43 health departments that were eligible, 30 were interested in participating. To select a representative and feasible sample of 6 health departments that met inclusion criteria, we generated all combinations of 6 from the 30 health departments that were eligible and interested. From the subset of combinations that met inclusion criteria, we selected 1 at random. Of 593,775 possible combinations of 6 counties, 15,177 (3%) met inclusion criteria. Sites in the selected subset were similar to all eligible sites in terms of health department characteristics and county demographics. Optimized probability sampling improved generalizability by ensuring an unbiased and representative sample of study sites.

Nuclear facility decommissioning and site remedial actions. Volume 6. A selected bibliography

DOE Office of Scientific and Technical Information (OSTI.GOV)

Owen, P.T.; Michelson, D.C.; Knox, N.P.

1985-09-01

This bibliography of 683 references with abstracts on the subject of nuclear facility decommissioning, uranium mill tailings management, and site remedial actions is the sixth in a series of annual reports prepared for the US Department of Energy's Remedial Action Programs. Foreign as well as domestic literature of all types - technical reports, progress reports, journal articles, conference papers, symposium proceedings, theses, books, patents, legislation, and research project descriptions - has been included. The bibliography contains scientific (basic research as well as applied technology), economic, regulatory, and legal literature pertinent to the US Department of Energy's remedial action program. Majormore » chapters are: (1) Surplus Facilities Management Program; (2) Nuclear Facilities Decommissioning; (3) Formerly Utilized Sites Remedial Action Program; (4) Facilities Contaminated with Natural Radioactivity; (5) Uranium Mill Tailings Remedial Action Program; (6) Grand Junction Remedial Action Program; (7) Uranium Mill Tailings Management; (8) Technical Measurements Center; and (9) General Remedial Action Program Studies. Chapter sections for chapters 1, 2, 5, and 7 include Design, Planning, and Regulations; Environmental Studies and Site Surveys; Health, Safety, and Biomedical Studies; Decontamination Studies; Dismantlement and Demolition; Site Stabilization and Reclamation; Waste Disposal; Remedial Action Experience; and General Studies. The references within each chapter or section are arranged alphabetically by leading author. References having no individual author are arranged by corporate affiliation or by publication description.« less

Characterization of selected biological, chemical, and physical conditions at fixed sites in the Upper Colorado River basin, Colorado, 1995-98

USGS Publications Warehouse

Deacon, Jeffrey R.; Mize, Scott V.; Spahr, Norman E.

1999-01-01

Biological community samples were collected at 15 sites in the Upper Colorado River Basin (UCOL) in Colorado as part of the National Water-Quality Assessment (NAWQA) Program. Sites sampled in two physiographic provinces, the Southern Rocky Mountains and the Colorado Plateau, represented agriculture, mining, urban and recreation, and mixed land uses and background conditions. Nine measures of water quality, which include information on nutrients, specific conductance (a surrogate for salinity), trace elements in streambed sediment, pesticides in fish tissue, fish communities, and macroinvertebrate richness and composition and stream habitat were used for comparisons among sites within the two physiographic provinces. Sampling sites from three other NAWQA study units?the Rio Grande Valley, the South Platte River Basin, and the Upper Snake River Basin study units?were categorized on the basis of land use and stream size in order to develop a larger data set for comparison to sites in the UCOL. Three categories of land use?forested (includes mining, urban and recreation, and background), agriculture, and mixed?were used for comparison to the UCOL fixed sites. Results indicated that all sites other than the Colorado River below Baker Gulch (a background site) showed some water-quality characteristics to be significantly affected. Results indicated that the concentrations of cadmium and zinc in streambed sediment at mining land-use sites in the Southern Rocky Mountains physiographic province generally were orders of magnitude higher than streambed-sediment concentrations at the background site. Streambed-sediment concentrations at mining land-use sites in the UCOL were greater than the 75th percentile of concentrations from sites in the three other NAWQA study units. Fish communities and habitat conditions were degraded at mining land-use sites compared to the background site. Ephemeroptera, Plecoptera, and Trichoptera (EPT) richness and the percentage of EPT were lower at mining land-use sites than at the background site and were less than the 50th percentile of those for sites from the three other NAWQA study units. Nutrient concentrations at urban and recreation sites in the Southern Rocky Mountain physiographic province generally were greater than concentrations at the background site and generally were between the 25th and 90th percentile of concentrations for sites from the three other NAWQA study units. Habitat conditions and fish communities at urban and recreation sites were slightly degraded compared to the background site. EPT richness and the percentage of EPT were lower at urban and recreation sites than at the background site and were between the 25th and 75th percentile of those for sites from the three other NAWQA study units. The percentage of Chironomidae, which may be indicative of pollutant-tolerant organisms, was higher at urban and recreation sites than at the background site. Mixed land-use sites in the Southern Rocky Mountains physiographic province had similar nutrient concentrations and similar cadmium and zinc streambed-sediment concentrations. Fish-community degradation index values were very different among the three mixed land-use sites in the Southern Rocky Mountains physiographic province. Larger percentages of omnivores and anomalies such as lesions and deformities at two mixed land-use sites resulted in higher degradation values of the fish community. Agriculture land-use sites had higher concentrations of nutrients and selenium than the background site in the Colorado Plateau physiographic province. Concentrations of p,p'-DDE in fish tissue at agriculture sites were higher than the 75th percentile of concentrations for sites from the three other NAWQA study units. Fish communities had degradation values near the 75th percentile for agriculture sites. The percentage of EPT was low at agriculture sites when compared to the background site. Two mixed land-use sites in the Colorado Plateau physiographi

A retrospective tiered environmental assessment of the Mount Storm Wind Energy Facility, West Virginia,USA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Efroymson, Rebecca Ann; Day, Robin; Strickland, M. Dale

Bird and bat fatalities from wind energy projects are an environmental and public concern, with post-construction fatalities sometimes differing from predictions. Siting facilities in this context can be a challenge. In March 2012 the U.S. Fish and Wildlife Service (USFWS) released Land-based Wind Energy Guidelines to assess collision fatalities and other potential impacts to species of concern and their habitats to aid in siting and management. The Guidelines recommend a tiered approach for assessing risk to wildlife, including a preliminary site evaluation that may evaluate alternative sites, a site characterization, field studies to document wildlife and habitat and to predictmore » project impacts, post construction studies to estimate impacts, and other post construction studies. We applied the tiered assessment framework to a case study site, the Mount Storm Wind Energy Facility in Grant County, West Virginia, USA, to demonstrate the use of the USFWS assessment approach, to indicate how the use of a tiered assessment framework might have altered outputs of wildlife assessments previously undertaken for the case study site, and to assess benefits of a tiered ecological assessment framework for siting wind energy facilities. The conclusions of this tiered assessment for birds are similar to those of previous environmental assessments for Mount Storm. This assessment found risk to individual migratory tree-roosting bats that was not emphasized in previous preconstruction assessments. Differences compared to previous environmental assessments are more related to knowledge accrued in the past 10 years rather than to the tiered structure of the Guidelines. Benefits of the tiered assessment framework include good communication among stakeholders, clear decision points, a standard assessment trajectory, narrowing the list of species of concern, improving study protocols, promoting consideration of population-level effects, promoting adaptive management through post-construction assessment and mitigation, and sharing information that can be used in other assessments.« less

Comparison of topical mupirocin and gentamicin in the prevention of peritoneal dialysis-related infections: A systematic review and meta-analysis.

PubMed

Tsai, Chia-Chi; Yang, Po-Sheng; Liu, Chien-Liang; Wu, Chih-Jen; Hsu, Yi-Chiung; Cheng, Shih-Ping

2018-01-01

Topical antibiotics have been shown to reduce exit-site infection and peritonitis. The aim of this study was to compare infection rates between mupirocin and gentamicin. Multiple comprehensive databases were searched systematically to include relevant randomized controlled trials and observational studies. Pooled risk ratios (RRs) and 95% confidence intervals were calculated for the incidences of exit-site infection and peritonitis. Seven studies (mupirocin group n = 458, gentamicin group n = 448) were analyzed for exit-site infection. The risk of gram-positive exit-site infection was similar between the groups. Gram-negative exit-site infection rate was higher in the mupirocin group (RR = 2.125, P = 0.037). Six studies were assessed the peritonitis risk. There was no difference in the gram-positive and -negative peritonitis rate. Topical use of gentamicin is associated with fewer exit-site infections caused by gram-negative organisms. Gentamicin has comparable efficacy to mupirocin for peritonitis and gram-positive exit-site infection. Copyright © 2017 Elsevier Inc. All rights reserved.

75 FR 66795 - TTM Technologies, Including On-Site Leased Workers From Kelly Services, Aerotek, and an On-Site...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-29

... follows: ``All workers TTM Technologies, including on-site leased workers from Kelly Services and Aerotek... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-64,993] TTM Technologies, Including On-Site Leased Workers From Kelly Services, Aerotek, and an On-Site Leased Worker From Orbotech...

Cornell University remote sensing program. [application to waste disposal site selection, study of drainage patterns, and water quality management.

NASA Technical Reports Server (NTRS)

Liang, T.; Mcnair, A. J.; Philipson, W. R.

1977-01-01

Aircraft and satellite remote sensing technology were applied in the following areas: (1) evaluation of proposed fly ash disposal sites; (2) development of priorities for drainage improvements; (3) state park analysis for rehabilitation and development; (4) watershed study for water quality planning; and (5) assistance project-landfill site selection. Results are briefly summarized. Other projects conducted include: (1) assessment of vineyard-related problems; (2) LANDSAT analysis for pheasant range management; (3) photo-historic evaluation of Revolutionary War sites; and (4) thermal analysis of building insulation. The objectives, expected benefits and actions, and status of these projects are described.

What do we mean by social networking sites?

PubMed

La Sala, Louise; Skues, Jason; Wise, Lisa

2014-01-01

The purpose of this study was to explore people's conceptual understanding of Social Networking Sites (SNSs) through exploring the combined use of a range of popular SNSs, including Facebook, Twitter, Myspace, Instagram, Tumblr, LinkedIn and Google Plus. Seventy-three adults, aged 18 to 63, participated in an online survey that used open-ended questions to ask how participants define and use different SNSs. Four themes were identified, including the explicit presentation and interpretation of different selves, the love-hate relationship with SNSs, privacy and danger concerns, and limited SNS knowledge. The findings from this study suggest that researchers need to consider how people use SNSs in combination as this influences the decisions people make about which SNS accounts they use and how they present themselves on these sites.

Prediction of the binding sites of huperzine A in acetylcholinesterase by docking studies

NASA Astrophysics Data System (ADS)

Pang, Yuan-Ping; Kozikowski, Alan P.

1994-12-01

We have performed docking studies with the SYSDOC program on acetylcholinesterase (AChE) to predict the binding sites in AChE of huperzine A (HA), which is a potent and selective, reversible inhibitor of AChE. The unique aspects of our docking studies include the following: (i) Molecular flexibility of the guest and the host is taken into account, which permits both to change their conformations upon binding. (ii) The binding energy is evaluated by a sum of energies of steric, electrostatic and hydrogen bonding interactions. In the energy calculation no grid approximation is used, and all hydrogen atoms of the system are treated explicitly. (iii) The energy of cation-π interactions between the guest and the host, which is important in the binding of AChE, is included in the calculated binding energy. (iv) Docking is performed in all regions of the host's binding cavity. Based on our docking studies and the pharmacological results reported for HA and its analogs, we predict that HA binds to the bottom of the binding cavity of AChE (the gorge) with its ammonium group interacting with Trp84, Phe330, Glu199 and Asp72 (catalytic site). At the the opening of the gorge with its ammonium group partially interacting with Trp279 (peripheral site). At the catalytic site, three partially overlapping subsites of HA were identified which might provide a dynamic view of binding of HA to the catalytic site.

Characteristics and Effectiveness of the U.S. State E-Government-to-Business Services

ERIC Educational Resources Information Center

Zhao, Jensen J.; Truell, Allen; Alexander, Melody W.

2008-01-01

This study examined the user-interface characteristics and effectiveness of the e-government-to-business (G2B) sites of the 50 U.S. states and Washington, D.C. A group of 306 online users were trained to assess the sites. The findings indicate that the majority of the state G2B sites included the user-interface characteristics that provided online…

Facebook as a Learning Tool? A Case Study on the Appropriation of Social Network Sites from Mobile Phones in Developing Countries

ERIC Educational Resources Information Center

Pimmer, Christoph; Linxen, Sebastian; Grohbiel, Urs

2012-01-01

This exploratory research investigates how students and professionals use social network sites (SNSs) in the setting of developing and emerging countries. Data collection included focus groups consisting of medical students and faculty as well as the analysis of a Facebook site centred on medical and clinical topics. The findings show how users,…

Site Preparation and Fertilization Effects on Growth of Slash Pine for Two Rotations

Treesearch

A.E. Tiarks; J.D. Haywood

1996-01-01

Two replicated site preparation studies were used to examine the effect of management on pine height and volume growth in the next rotation on Paleudults. Treatments included notillage,flat disking, bedding, and fertilization. The first rotation of planted slash pine (pinus elliottii Engelm.var. eliottii)was measured for 15 yr on one site and 20 yr at the other,...

The effect of small rodents on northern red oak acorns in north-central West Virginia

Treesearch

Linda S. Gribko; David M. Hix

1993-01-01

The effects of small mammals on surface-sown northern red oak (Quercus rubra) acorns was assessed in highly productive Appalachian hardwood stands. Study plots were established in October 1990 on excellent (average site index of 89 feet for red oak) and good (average site index of 72 feet) sites. Each plot included: 1) a rodent-proof exclosure, 2) an exclosure...

Bactibilia and surgical site infection after open cholecystectomy.

PubMed

Velázquez-Mendoza, José Dolores; Alvarez-Mora, Moisés; Velázquez-Morales, César Augusto; Anaya-Prado, Roberto

2010-01-01

Bactibilia is the presence of bacteria in gall bladder bile and may play a role in the appearance of septic complications. It has been related to increased rates of surgical site infection after cholecystectomy. In this study we investigated whether bactibilia correlates with the presence of surgical site infection after cholecystectomy. In this observational and descriptive study we investigated those patients operated by open cholecystectomy because of chronic cholecystitis. Patients had bile culture during surgery (January-December 2006). There were two study groups: patients with negative biliary culture (group 1) and patients with positive biliary culture (group 2). Variables were age, gender, biliary culture reports, abscess, cellulitis, seroma, and hematoma. Statistical analysis included Pearson chi(2) or Fisher's exact test. For independent variables, Student t-test was used. Eighty patients were included (n = 40 per group). There were 24 males (30%) and 56 females (70%) who had open cholecystectomy and had biliary culture. General morbidity was 42.50% and surgical site infection rate in general was 11.25%. There were two patients with abscesses and two patients with cellulitis in group 1. There were four patients with abscesses and one patient with cellulitis in group 2. There was no statistically significant difference when comparing surgical site infection in both groups. The presence of bacteria in gall bladder cultures does not correlate with the development of surgical site infection after open cholecystectomy.

77 FR 53914 - Horton Automatics, Inc., a Subsidiary of Overhead Door Corporation Including On-Site Leased...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-04

...., a Subsidiary of Overhead Door Corporation Including On-Site Leased Workers From Remedy Intelligent..., including on-site leased workers from Remedy Intelligent Staffing, Corpus Christi, Texas. The workers are... Automatics, Inc., a subsidiary of Overhead Door Corporation, including on-site leased workers from Remedy...

76 FR 19466 - Masco Builder Cabinet Group Including On-Site Leased Workers From Reserves Network, Reliable...

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2011-04-07

... Builder Cabinet Group Including On-Site Leased Workers From Reserves Network, Reliable Staffing, and Third Dimension Waverly, OH; Masco Builder Cabinet Group Including On-Site Leased Workers From Reserves Network... Group including on-site leased workers from Reserves Network, Jackson, Ohio. The workers produce...

78 FR 49292 - Northshore Mining Company, a Subsidiary of Cliffs Natural Resources, Including On-Site Leased...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-13

... Mining Company, a Subsidiary of Cliffs Natural Resources, Including On-Site Leased Workers From Vanhouse... Cliffs Natural Resources, Including On- Site Leased Workers From Vanhouse, Express Employment and Our... Natural Resources, including on-site leased workers from VanHouse and Express Employment, Silver Bay...

Surgical Scar Site Recurrence in Patients With Cervical Cancer on 18F-FDG PET-CT: A Case-Control Study.

PubMed

Dhull, Varun S; Khangembam, Bangkim C; Sharma, Punit; Rana, Neelima; Verma, Satyavrat; Sharma, Dayanand; Shamim, Shamim A; Kumar, Sunesh; Kumar, Rakesh

2016-02-01

The purpose of this study was to assess the role of fluorine 18 ((18)F)-fluorodeoxyglucose positron emission tomography-computed tomography ((18)F-FDG PET-CT) in evaluating various parameters in patients with surgical scar site recurrence in cervical carcinoma. Data of all patients with cervical cancer (n = 329) who underwent PET-CT at our institute between 2005 and 2013 was reviewed. Of these 329 patients, 132 patients who were surgically treated and underwent restaging/follow-up PET-CT were included in the present study for final analysis. Tumor recurrence at the abdominal surgical scar site was looked for. Abnormal uptakes suggestive of active disease at other sites were also noted. Maximum standardized uptake value was measured for all the lesions. Patients with scar site recurrence were taken as cases (n = 6), whereas the remaining patients served as controls (n = 126). Comparison with conventional imaging modalities was made wherever available. Histopathological examination was always sought for. The incidence of scar site recurrence after surgery was found to be 4.5% (6/117). A total of 56 of 132 patients had recurrent disease, including 6 patients with scar site recurrence. All of the patients with scar site recurrence also had recurrent disease at other sites (local, nodal, or distant). Conventional imaging modalities were available in 4 of these 6 patients and detected scar site recurrence in 3 of those 4 patients. In patients with scar site recurrence, the mean ± SD time to scar site recurrence was 14.0 ± 10.9 months (median, 10 months; range, 7-36 months). Significant difference was seen between cases and control for International Federation of Genecology and Oncology stage (P = 0.001) and nodal recurrence (P = 0.007). Additionally, age, nodal recurrence, distant recurrence, and scar site recurrence were significantly associated with death. Scar site recurrence carries a poor prognosis, and the incidence is much higher than previously known when PET-CT is used as a modality for its detection.

Selected hydrologic data from a wastewater spray disposal site on Hilton Head Island, South Carolina

USGS Publications Warehouse

Speiran, G.K.; Belval, D.L.

1985-01-01

This study presents data collected during a study of the effects on the water table aquifer from wastewater application at rates of up to 5 inches per week on a wastewater spray disposal site on Hilton Head Island, South Carolina. The study was conducted from April 1982 through December 1983. The disposal site covers approximately 14 acres. Water level and water quality data from organic, inorganic, and nutrient analyses from the water table aquifer to a depth of 30 ft and similar water quality data from the wastewater treatment plant are included. (USGS)

Fuel quality/processing study. Volume 4: On site processing studies

NASA Technical Reports Server (NTRS)

Jones, G. E., Jr.; Cutrone, M.; Doering, H.; Hickey, J.

1981-01-01

Fuel treated at the turbine and the turbine exhaust gas processed at the turbine site are studied. Fuel treatments protect the turbine from contaminants or impurities either in the upgrading fuel as produced or picked up by the fuel during normal transportation. Exhaust gas treatments provide for the reduction of NOx and SOx to environmentally acceptable levels. The impact of fuel quality upon turbine maintenance and deterioration is considered. On site costs include not only the fuel treatment costs as such, but also incremental costs incurred by the turbine operator if a turbine fuel of low quality is not acceptably upgraded.

Atmospheric studies in complex terrain: a planning guide for future studies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Orgill, M.M.

The objective of this study is to assist the US Department of Energy in Conducting its atmospheric studies in complex terrain (ASCOT0 by defining various complex terrain research systems and relating these options to specific landforms sites. This includes: (1) reviewing past meteorological and diffusion research on complex terrain; (2) relating specific terrain-induced airflow phenomena to specific landforms and time and space scales; (3) evaluating the technical difficulty of modeling and measuring terrain-induced airflow phenomena; and (4) avolving severdal research options and proposing candidate sites for continuing and expanding field and modeling work. To evolve research options using variable candidatemore » sites, four areas were considered: site selection, terrain uniqueness and quantification, definition of research problems and research plans. 36 references, 111 figures, 20 tables.« less

Energy benchmarking in wastewater treatment plants: the importance of site operation and layout.

PubMed

Belloir, C; Stanford, C; Soares, A

2015-01-01

Energy benchmarking is a powerful tool in the optimization of wastewater treatment plants (WWTPs) in helping to reduce costs and greenhouse gas emissions. Traditionally, energy benchmarking methods focused solely on reporting electricity consumption, however, recent developments in this area have led to the inclusion of other types of energy, including electrical, manual, chemical and mechanical consumptions that can be expressed in kWh/m3. In this study, two full-scale WWTPs were benchmarked, both incorporated preliminary, secondary (oxidation ditch) and tertiary treatment processes, Site 1 also had an additional primary treatment step. The results indicated that Site 1 required 2.32 kWh/m3 against 0.98 kWh/m3 for Site 2. Aeration presented the highest energy consumption for both sites with 2.08 kWh/m3 required for Site 1 and 0.91 kWh/m3 in Site 2. The mechanical energy represented the second biggest consumption for Site 1 (9%, 0.212 kWh/m3) and chemical input was significant in Site 2 (4.1%, 0.026 kWh/m3). The analysis of the results indicated that Site 2 could be optimized by constructing a primary settling tank that would reduce the biochemical oxygen demand, total suspended solids and NH4 loads to the oxidation ditch by 55%, 75% and 12%, respectively, and at the same time reduce the aeration requirements by 49%. This study demonstrated that the effectiveness of the energy benchmarking exercise in identifying the highest energy-consuming assets, nevertheless it points out the need to develop a holistic overview of the WWTP and the need to include parameters such as effluent quality, site operation and plant layout to allow adequate benchmarking.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davis, B.E.; Krajewski, S.A.; Ahner, P.F.

The site qualification program for the North Knobs UCG site near Rawlins, Wyoming has been completed. This site will be the location for the field tests of Underground Coal Gasification of Steeply Dipping Beds undertaken by Gulf Research and Development Company for DOE in a cost shared contract. Site characterization included a comprehensive geotechnical analysis along with vegetation, historical, and archeological studies. The G coal seam chosen for these tests is a subbituminous B coal with a true seam thickness of 22 feet and has thin coal benches above and below the main seam. The water table is at 90more » feet below the surface. Hydrologic studies have defined the seam as an aquiclude (non-aquifer). The site is deemed restorable to regulatory requirements. Evaluation of this site indicates total acceptability for the three-test program planned by GR and DC.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davis, B.E.; Krajewski, S.A.; Ahner, P.F.

The site qualification program for the North Knobs UCG site near Rawlins, Wyoming has been completed. This site will be the location for the field tests of Underground Coal Gasification of Steeply Dipping Beds undertaken by Gulf Research and Development Company for DOE in a cost shared contract. Site characterization included a comprehensive geotechnical analysis along with vegetation, historical, and archeological studies. The G coal seam chosen for these tests is a subbituminous B coal with a true seam thickness of 22 feet and has thin coal benches above and below the main seam. The water table is at 90more » feet below the surface. Hydrologic studies have defined the seam as an aquiclude (nonaquifer). The site is deemed restorable to regulatory requirements. Evaluation of this site indicates total acceptability for the three-test program planned by GR and DC.« less

Archaeology: site studies, activation analysis, preservation, and remote sensing. Volume 3. 1978-November 1979 (a bibliography with abstracts). Report for 1978-November 79

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cavagnaro, D.

1979-12-01

These citations of federally-funded research are divided into two parts; namely, a chemical analysis of archaeological specimens, and general studies. The chemical analysis section deals primarily with activation analysis. Articles examined include metals, pottery, coins, paintings, soils, glass, and paper from Medieval, Grecian, Egyptian, Mayan, and prehistoric times. The general studies section cites other archaeological research, including results of excavation from the United States. Also covered is work on preservation of artifacts and remote sensing for the site location. (This updated bibliography contains 237 abstracts, 149 of which are new entries to the previous edition.)

Archaeology: site studies, activation analysis, preservation, and remote sensing. December 1979-December 1980 (citations from the NTIS Data Base). Report for December 1970-December 1980

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1981-01-01

These citations of federally-funded research contains the chemical analysis of archaeological specimens, as well as general studies. The chemical analysis deals primarily with activation analysis. Articles examined include metals, pottery, coins, paintings, soils, glass, and paper from Medieval, Grecian, Egyptian, Mayan, and prehistoric times. The general studies cites other archaeological research, including results of excavation from the United States. Also covered is work on preservation of artifacts and remote sensing for the site location. (This updated bibliography contains 133 citations, all of which are new entries to the previous edition.)

Archaeology: site studies, activation analysis, preservation, and remote sensing. Volume 2. 1977 (a bibliography with abstracts). Report for 1977

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cavagnaro, D.

1979-12-01

The cited reports of Federally-funded research are divided into two parts: namely, a chemical analysis of archaeological specimens, and general studies. The chemical analysis section deals primarily with activation analysis. Artifacts examined include metals, pottery, coins, paintings, soils, glass, and paper from Medieval, Grecian, Egyptian, Mayan, and prehistoric times. The general studies section discusses other archaeological research, including results of excavation from the United States. Also covered is work on preservation of artifacts and remote sensing for the site location. (This updated bibliography contains 128 abstracts, none of which are new entries to the previous edition.)

Archaeology: site studies, activation analysis, preservation, and remote sensing. volume 2. 1977-november, 1978 (a bibliography with abstracts). Report for 1977-Nov 78

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cavagnaro, D.M.

1978-11-01

These citations of Federally-funded research are divided into two parts; namely, a chemical analysis of archaeological specimens, and general studies. The chemical analysis section deals primarily with activation analysis. Articles examined include metals, pottery, coins, paintings, soils, glass, and paper from Medieval, Grecian, Egyptian, Mayan and prehistoric times. The general studies section cites other archaeological research, including results of excavation from the United States. Also covered is work on preservation of artifacts and remote sensing for the site location. (This updated bibliography contains 209 abstracts, 141 of which are new entries to the previous edition.)

Hydrologic and micrometeorologic data from an unsaturated zone study at a low-level radioactive waste burial site near Barnwell, South Carolina

USGS Publications Warehouse

Dennehy, K.F.; McMahon, P.B.

1985-01-01

Two years of selected hydrologic and micrometeorologic data collected at a low-level radioactive waste burial site near Barnwell, South Carolina are available on magnetic tape in card-image format. Hydrologic data include daily measurements of soil-moisture tension, soil-moisture specific conductance, and soil temperature at four monitoring site locations. Micrometeorlogic data include hourly measurements for the following parameters: dry- and wet-bulb temperatures, soil temperatures, soil heat flux, wind speeds and direction, incoming and reflected short-wave solar radiation, incoming and emitted long-wave radiation, net radiation and precipitation. (USGS)

Ensuring quality Website redesign: the University of Maryland's experience.

PubMed

Fuller, D M; Hinegardner, P G

2001-10-01

The Web Redesign Committee at the Health Sciences and Human Services Library (HS/HSL) of the University of Maryland was formed to evaluate its site and oversee the site's redesign. The committee's goal was to design a site that would be functional, be usable, and provide the library with a more current image. Based on a literature review and discussions with colleagues, a usability study was conducted to gain a better understanding of how the Website was used. Volunteers from across the campus participated in the study. A Web-based survey was also used to gather feedback. To complement user input, library staff were asked to review the existing site. A prototype site was developed incorporating suggestions obtained from the evaluation mechanisms. The usability study was particularly useful because it identified problem areas, including terminology, which would have been overlooked by library staff. A second usability study was conducted to refine the prototype. The new site was launched in the spring of 2000. The usability studies were valuable mechanisms in designing the site. Users felt invested in the project, and the committee received valuable feedback. This process led to an improved Website and higher visibility for the library on campus.

Uranium-Bearing Evaporite Mineralization Influencing Plume Persistence. Literature Review and DOE-LM Site Surveys

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

This report on evaporite mineralization was completed as an Ancillary Work Plan for the Applied Studies and Technology program under the U.S. Department of Energy (DOE) Office of Legacy Management (LM). This study reviews all LM sites under Title I and Title II of the Uranium Mill Tailings Radiation Control Act (UMTRCA) and one Decontamination and Decommissioning site to provide (1) a summary of which sites have evaporite deposits, (2) any available quantitative geochemical and mineralogical analyses, and (3) references to relevant reports. In this study, “evaporite” refers to any secondary mineral precipitate that occurs due to a loss ofmore » water through evaporative processes. This includes efflorescent salt crusts, where this term refers to a migration of dissolved constituents to the surface with a resulting salt crust, where “salt” can refer to any secondary precipitate, regardless of constituents. The potential for the formation of evaporites at LM sites has been identified, and may have relevance to plume persistence issues. Evaporite deposits have the potential to concentrate and store contaminants at LM sites that could later be re-released. These deposits can also provide a temporary storage mechanism for carbonate, chloride, and sulfate salts along with uranium and other contaminants of concern (COCs). Identification of sites with evaporites will be used in a new technical task plan (TTP), Persistent Secondary Contaminant Sources (PeSCS), for any proposed additional sampling and analyses. This additional study is currently under development and will focus on determining if the dissolution of evaporites has the potential to hinder natural flushing strategies and impact plume persistence. This report provides an initial literature review on evaporites followed by details for each site with identified evaporites. The final summary includes a table listing of all relevant LM sites regardless of evaporite identification.« less

Site productivity and diversity of the Middle Mountain long-term soil productivity study, West Virginia: Pre-experimental site characterization

Treesearch

Mary Beth Adams

2018-01-01

To better understand the impacts of a changing environment and interactions with forest management options for forest resources, including soil, large long-term experiments are required. Such experiments require careful documentation of reference or pre-experimental conditions. This publication describes the Middle Mountain Long-term Soil Productivity (LTSP) Study,...

Spacelab Level 4 Programmatic Implementation Assessment Study. Volume 4: Executive summary

NASA Technical Reports Server (NTRS)

1978-01-01

The study objectives of the Spacelab level 4 analysis were defined, along with the most significant results. The approach used in the synthesis and selection of alternate level 4 integration is described; the options included distributed site, lead center, and launch site. Principal characteristics, as well as the functional flow diagrams for each option, are presented and explained.

A multi-criteria targeting approach to neutral grassland conservation.

PubMed

Bayliss, Julian; Helyar, Alice; Lee, John T; Thompson, Stewart

2003-02-01

Resources for creating and managing rare habitats are limited, and a targeting approach aimed at identifying the most viable sites for habitat conservation is therefore desirable. This study developed a multi-criteria targeting approach to site conservation for two rare grassland types, based on a suite of biotic and abiotic factors managed within a Geographical Information System. A number of biotic and abiotic criteria were assessed to evaluate the biodiversity status of grassland sites. Biotic factors included species diversity, species richness and species rarity; and abiotic factors included patch area, position in the ecological unit and the influence of surrounding land use. Each criterion was given equal weighting and a final biodiversity value for each patch was calculated; the patch with the highest cumulative rank score was deemed the patch with the greatest biodiversity. Each site was then examined in relation to agricultural land under the existing management prescriptions of the Upper Thames Tributaries Environmentally Sensitive Area (UTTESA). Sites identified with high biodiversity potential, but currently not included under management prescriptions, were targeted for future inclusion in the ESA scheme. The targeting approach demonstrated how the national Lowland Meadows habitat action plan creation target of 500 ha could be achieved in the UTTESA. The fact that this target figure was so easily attained within this study area highlighted the possible underestimation of national habitat creation targets.

Improving site selection in clinical studies: a standardised, objective, multistep method and first experience results.

PubMed

Hurtado-Chong, Anahí; Joeris, Alexander; Hess, Denise; Blauth, Michael

2017-07-12

A considerable number of clinical studies experience delays, which result in increased duration and costs. In multicentre studies, patient recruitment is among the leading causes of delays. Poor site selection can result in low recruitment and bad data quality. Site selection is therefore crucial for study quality and completion, but currently no specific guidelines are available. Selection of sites adequate to participate in a prospective multicentre cohort study was performed through an open call using a newly developed objective multistep approach. The method is based on use of a network, definition of objective criteria and a systematic screening process. Out of 266 interested sites, 24 were shortlisted and finally 12 sites were selected to participate in the study. The steps in the process included an open call through a network, use of selection questionnaires tailored to the study, evaluation of responses using objective criteria and scripted telephone interviews. At each step, the number of candidate sites was quickly reduced leaving only the most promising candidates. Recruitment and quality of data went according to expectations in spite of the contracting problems faced with some sites. The results of our first experience with a standardised and objective method of site selection are encouraging. The site selection method described here can serve as a guideline for other researchers performing multicentre studies. ClinicalTrials.gov: NCT02297581. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Final environmental impact statement. Waste Isolation Pilot Plant

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1980-10-01

This volume contains the appendices for the Final Environmental Impact Statement for the Waste Isolation Pilot Plant (WIPP). Alternative geologic environs are considered. Salt, crystalline rock, argillaceous rock, and tuff are discussed. Studies on alternate geologic regions for the siting of WIPP are reviewed. President Carter's message to Congress on the management of radioactive wastes and the findings and recommendations of the interagency review group on nuclear waste management are included. Selection criteria for the WIPP site including geologic, hydrologic, tectonic, physicochemical compatability, and socio-economic factors are presented. A description of the waste types and the waste processing procedures aremore » given. Methods used to calculate radiation doses from radionuclide releases during operation are presented. A complete description of the Los Medanos site, including archaeological and historic aspects is included. Environmental monitoring programs and long-term safety analysis program are described. (DMC)« less

Initial Field Trial of a Coach-Supported Web-Based Depression Treatment.

PubMed

Schueller, Stephen M; Mohr, David C

2015-08-01

Early web-based depression treatments were often self-guided and included few interactive elements, instead focusing mostly on delivering informational content online. Newer programs include many more types of features. As such, trials should analyze the ways in which people use these sites in order to inform the design of subsequent sites and models of support. The current study describes of a field trial consisting of 9 patients with major depressive disorder who completed a 12-week program including weekly coach calls. Patients usage varied widely, however, patients who formed regular patterns tended to persist with the program for the longest. Future sites might be able to facilitate user engagement by designing features to support regular use and to use coaches to help establish patterns to increase long-term use and benefit.

Missing Data and Influential Sites: Choice of Sites for Phylogenetic Analysis Can Be As Important As Taxon Sampling and Model Choice

PubMed Central

Shavit Grievink, Liat; Penny, David; Holland, Barbara R.

2013-01-01

Phylogenetic studies based on molecular sequence alignments are expected to become more accurate as the number of sites in the alignments increases. With the advent of genomic-scale data, where alignments have very large numbers of sites, bootstrap values close to 100% and posterior probabilities close to 1 are the norm, suggesting that the number of sites is now seldom a limiting factor on phylogenetic accuracy. This provokes the question, should we be fussy about the sites we choose to include in a genomic-scale phylogenetic analysis? If some sites contain missing data, ambiguous character states, or gaps, then why not just throw them away before conducting the phylogenetic analysis? Indeed, this is exactly the approach taken in many phylogenetic studies. Here, we present an example where the decision on how to treat sites with missing data is of equal importance to decisions on taxon sampling and model choice, and we introduce a graphical method for illustrating this. PMID:23471508

Database for earthquake strong motion studies in Italy

USGS Publications Warehouse

Scasserra, G.; Stewart, J.P.; Kayen, R.E.; Lanzo, G.

2009-01-01

We describe an Italian database of strong ground motion recordings and databanks delineating conditions at the instrument sites and characteristics of the seismic sources. The strong motion database consists of 247 corrected recordings from 89 earthquakes and 101 recording stations. Uncorrected recordings were drawn from public web sites and processed on a record-by-record basis using a procedure utilized in the Next-Generation Attenuation (NGA) project to remove instrument resonances, minimize noise effects through low- and high-pass filtering, and baseline correction. The number of available uncorrected recordings was reduced by 52% (mostly because of s-triggers) to arrive at the 247 recordings in the database. The site databank includes for every recording site the surface geology, a measurement or estimate of average shear wave velocity in the upper 30 m (Vs30), and information on instrument housing. Of the 89 sites, 39 have on-site velocity measurements (17 of which were performed as part of this study using SASW techniques). For remaining sites, we estimate Vs30 based on measurements on similar geologic conditions where available. Where no local velocity measurements are available, correlations with surface geology are used. Source parameters are drawn from databanks maintained (and recently updated) by Istituto Nazionale di Geofisica e Vulcanologia and include hypocenter location and magnitude for small events (M< ??? 5.5) and finite source parameters for larger events. ?? 2009 A.S. Elnashai & N.N. Ambraseys.

[Impact of volatile sulphur compounds in periodontal pockets on initial periodontal therapy].

PubMed

Li, Xiao-Jun; Dong, Ling-Ling; Kong, Jing-Jia

2008-07-01

To investigate the relationship of volatile sulphur compounds((VSC)levels in periodontal pockets with severity of periodontitis, and the impact of VSC on the result of initial periodontal therapy. Twenty-five patients with chronic periodontitis(CP)(13 males and 12 females with average age of 35) were included in this study. Clinical periodontal parameters, plaque index, probing depth(PD), attachment loss(AL), and bleeding on probing(BOP) were recorded before and 3 months after the initial therapy. VSC levels were measured with a portable monitor in a digital score ranging from 0.0 to 5.0. All of 5 054 sites for 840 teeth were included in this study. Before treatment the percentage of VSC-positive sites was 17.1%, 52.3% and 86.0% for shallow (PD<3 mm), moderate(PD 4-6 mm) and deep (PD>7 mm) pocket, respectively (P<0.001). In most VSC-positive sites the VSC levels were<1.0. Percentage of sites with a high VSC levels was significantly different among three groups (P<0.01). All clinical parameters in VSC-negative sites were reduced significantly following the initial therapy. The reduction of PD and AL in VSC-positive sites by treatment was less marked than that in VSC-negative sites. VSC in periodontal pockets may be a potential indicator for detecting severity of CP and a useful predictor for therapeutic success.

Geophysical Survey of Proposed Construction Site with Possible Faulting, East San Francisco Bay Hills, California

NASA Astrophysics Data System (ADS)

Galvin, J. L.; Deqiang, C.; Abimbola, A.; Shuler, S.; Hayashi, K.; Fox, J.; Craig, M. S.; Strayer, L. M.; Drumm, P.

2015-12-01

We conducted a geophysical study at a site proposed for a new dorm building prior to trenching planned as part of a separate fault investigation study. The study area was located on the south side of the CSU East Bay campus, roughly 100 - 300 m SSE of the current dorm complex. In addition to its proximity to the Hayward Fault, several smaller faults have been previously mapped within the proposed location, including the East and West Dibblee Faults. These faults are thought to represent contacts between the Leona Rhyolite and the Knoxville Formation. Data acquisition included seismic, resistivity, and GPS data collected in an effort to develop a better understanding of the geological and structural profile of this area, including the location of lithologic contacts, faults, and the thickness of soil and fill. Geophysical profiles were collected over the locations of future trenches. The survey included geophysical lines that were located coincident with two planned trenching sites, which were chosen to intersect mapped faults. Survey positions were recorded using differential GPS. Seismic refraction and MASW (multichannel analysis of surface waves) surveys were performed over two of the planned trench sites using a 48-channel seismographic system with 4.5 Hz geophones and a 10-lb sledgehammer. For one of the lines, geophones were spaced every 3 m with a total spread length of 141 m and a shot spacing of 9 m. For the second line, geophones were spaced every 4 m with a total spread length of 188 m. Shots were taken every 12 m. Resistivity surveys were also performed along one of the line locations using both a capacitively-coupled dipole (CCD) system and 48-electrode system. Geospatial data for the survey area were compiled, including 0.3 m color orthoimagery and vector line files for geologic unit boundaries and presumed fault locations. The products of this study will include the geophysical response of geologic formations, location of unit contacts and faults, thickness of soil and fill, shear wave velocity (VS and VS30). The results of this study will enable improved seismic hazard assessment of the site and will contribute to a better understanding of the overall geologic profile of this area.

76 FR 35026 - Hutchinson Technology, Inc., Including On-Site Workers Leased From Doherty, Including Workers...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-15

... Technology, Inc., Including On-Site Workers Leased From Doherty, Including Workers Whose Unemployment... Technology, Inc., Including On-Site Workers Leased From Doherty, Including Workers Whose Unemployment..., Minnesota locations of the subject firm had their wages reported under a separate unemployment insurance (UI...

Multidisciplinary approaches to managing osteoarthritis in multiple joint sites: a systematic review.

PubMed

Finney, Andrew; Healey, Emma; Jordan, Joanne L; Ryan, Sarah; Dziedzic, Krysia S

2016-07-08

The National Institute for Health and Care Excellence's Osteoarthritis (OA) guidelines recommended that future research should consider the benefits of combination therapies in people with OA across multiple joint sites. However, the clinical effectiveness of such approaches to OA management is unknown. This systematic review therefore aimed to identify the clinical and cost effectiveness of multidisciplinary approaches targeting multiple joint sites for OA in primary care. A systematic review of randomised controlled trials. Computerised bibliographic databases were searched (MEDLINE, EMBASE, CINAHL, PsychINFO, BNI, HBE, HMIC, AMED, Web of Science and Cochrane). Studies were included if they met the following criteria; a randomised controlled trial (RCT), a primary care population with OA across at least two different peripheral joint sites (multiple joint sites), and interventions undertaken by at least two different health disciplines (multidisciplinary). The Cochrane 'Risk of Bias' tool and PEDro were used for quality assessment of eligible studies. Clinical and cost effectiveness was determined by extracting and examining self-reported outcomes for pain, function, quality of life (QoL) and health care utilisation. The date range for the search was from database inception until August 2015. The search identified 1148 individual titles of which four were included in the review. A narrative review was conducted due to the heterogeneity of the included trials. Each of the four trials used either educational or exercise interventions facilitated by a range of different health disciplines. Moderate clinical benefits on pain, function and QoL were reported across the studies. The beneficial effects of exercise generally decreased over time within all studies. Two studies were able to show a reduction in healthcare utilisation due to a reduction in visits to a physiotherapist or a reduction in x-rays and orthopaedic referrals. The intervention that showed the most promise used educational interventions delivered by GPs with reinforcement by practice nurses. There are currently very few studies that target multidisciplinary approaches suitable for OA across multiple joint sites, in primary care. A more consistent approach to outcome measurement in future studies of this nature should be considered to allow for better comparison.

AmeriFlux US-Wkg Walnut Gulch Kendall Grasslands

DOE Data Explorer

Scott, Russell [United States Department of Agriculture

2016-01-01

This is the AmeriFlux version of the carbon flux data for the site US-Wkg Walnut Gulch Kendall Grasslands. Site Description - This site is located in a small, intensively-studied, experimental watershed within USDA-ARS's Walnut Gulch Experimental Watershed. Eddy covariance measurements of energy, water and CO2 fluxes began in the spring of 2004, though meteorological (including Bowen ratio) and hydrological measurements are available much further back.

Implementation for GREAT I Study.

DTIC Science & Technology

1981-06-01

population centers where greater beneficial use is expected. ’Most of the sites selected are not owned by the Federal Government. Many factors could prevent ...have to be five to six times the dredged material volume. Berming is generally required to prevent encroachment beyond the placement site. The site...fish and wildlife and/ or recreation under its cost-sharing authorities (Public Law 89-72 and Code 710 Prgram ), including facilitating the

Summary and Comparison of Multiphase Streambed Scour Analysis at Selected Bridge Sites in Alaska

USGS Publications Warehouse

Conaway, Jeffrey S.

2004-01-01

The U.S. Geological Survey and the Alaska Department of Transportation and Public Facilities undertook a cooperative multiphase study of streambed scour at selected bridges in Alaska beginning in 1994. Of the 325 bridges analyzed for susceptibility to scour in the preliminary phase, 54 bridges were selected for a more intensive analysis that included site investigations. Cross-section geometry and hydraulic properties for each site in this study were determined from field surveys and bridge plans. Water-surface profiles were calculated for the 100- and 500-year floods using the Hydrologic Engineering Center?s River Analysis System and scour depths were calculated using methods recommended by the Federal Highway Administration. Computed contraction-scour depths for the 100- and 500-year recurrence-interval discharges exceeded 5 feet at six bridges, and pier-scour depths exceeded 10 feet at 24 bridges. Complex pier-scour computations were made at 10 locations where the computed contraction-scour depths would expose pier footings. Pressure scour was evaluated at three bridges where the modeled flood water-surface elevations intersected the bridge structure. Site investigation at the 54 scour-critical bridges was used to evaluate the effectiveness of the preliminary scour analysis. Values for channel-flow angle of attack and approach-channel width were estimated from bridge survey plans for the preliminary study and were measured during a site investigation for this study. These two variables account for changes in scour depths between the preliminary analysis and subsequent reanalysis for most sites. Site investigation is needed for best estimates of scour at bridges with survey plans that indicate a channel-flow angle of attack and for locations where survey plans did not include sufficient channel geometry upstream of the bridge.

Incidence and risk factors for surgical site infection after open reduction and internal fixation of tibial plateau fracture: A systematic review and meta-analysis.

PubMed

Shao, Jiashen; Chang, Hengrui; Zhu, Yanbin; Chen, Wei; Zheng, Zhanle; Zhang, Huixin; Zhang, Yingze

2017-05-01

This study aimed to quantitatively summarize the risk factors associated with surgical site infection after open reduction and internal fixation of tibial plateau fracture. Medline, Embase, CNKI, Wanfang database and Cochrane central database were searched for relevant original studies from database inception to October 2016. Eligible studies had to meet quality assessment criteria according to the Newcastle-Ottawa Scale, and had to evaluate the risk factors for surgical site infection after open reduction and internal fixation of tibial plateau fracture. Stata 11.0 software was used for this meta-analysis. Eight studies involving 2214 cases of tibial plateau fracture treated by open reduction and internal fixation and 219 cases of surgical site infection were included in this meta-analysis. The following parameters were identified as significant risk factors for surgical site infection after open reduction and internal fixation of tibial plateau fracture (p < 0.05): open fracture (OR 3.78; 95% CI 2.71-5.27), compartment syndrome (OR 3.53; 95% CI 2.13-5.86), operative time (OR 2.15; 95% CI 1.53-3.02), tobacco use (OR 2.13; 95% CI 1.13-3.99), and external fixation (OR 2.07; 95% CI 1.05-4.09). Other factors, including male sex, were not identified as risk factors for surgical site infection. Patients with the abovementioned medical conditions are at risk of surgical site infection after open reduction and internal fixation of tibial plateau fracture. Surgeons should be cognizant of these risks and give relevant preoperative advice. Copyright © 2017. Published by Elsevier Ltd.

A Guide to Minnesota Environmental Education Areas.

ERIC Educational Resources Information Center

Fisher, Wes, Comp.; Gruchow, Nancy, Comp.

More than 400 areas in Minnesota, useful as sites for environmental studies, are catalogued in this guide. They include state parks and waysides, state forests, state wildlife management areas, waterfowl production areas, national forests, nature centers and preserves, metropolitan, county and city parks, outdoor education school sites, school…

Problems in shallow land disposal of solid low-level radioactive waste in the united states

USGS Publications Warehouse

Stevens, P.R.; DeBuchananne, G.D.

1976-01-01

Disposal of solid low-level wastes containing radionuclides by burial in shallow trenches was initiated during World War II at several sites as a method of protecting personnel from radiation and isolating the radionuclides from the hydrosphere and biosphere. Today, there are 11 principal shallow-land burial sites in the United States that contain a total of more than 1.4 million cubic meters of solid wastes contaminated with a wide variety of radionuclides. Criteria for burial sites have been few and generalized and have contained only minimal hydrogeologic considerations. Waste-management practices have included the burial of small quantities of long-lived radionuclides with large volumes of wastes contaminated with shorter-lived nuclides at the same site, thereby requiring an assurance of extremely long-time containment for the entire disposal site. Studies at 4 of the 11 sites have documented the migration of radionuclides. Other sites are being studied for evidence of containment failure. Conditions at the 4 sites are summarized. In each documented instance of containment failure, ground water has probably been the medium of transport. Migrating radionuclides that have been identified include90Sr,137Cs,106Ru,239Pu,125Sb,60Co, and3H. Shallow land burial of solid wastes containing radionuclides can be a viable practice only if a specific site satisfies adequate hydrogeologic criteria. Suggested hydrogeologic criteria and the types of hydrogeologic data necessary for an adequate evaluation of proposed burial sites are given. It is mandatory that a concomitant inventory and classification be made of the longevity, and the physical and chemical form of the waste nuclides to be buried, in order that the anticipated waste types can be matched to the containment capability of the proposed sites. Ongoing field investigations at existing sites will provide data needed to improve containment at these sites and help develop hydrogeologic criteria for new sites. These studies have necessitated the development of special drilling, sampling, well construction, and testing techniques. A recent development in borehole geophysical techniques is downhole spectral gammaray analysis which not only locates but identifies specific radionuclides in the subsurface. Field investigations are being supplemented by laboratory studies of the hydrochemistry of the transuranic elements, the kinetics of solid-liquid phase interactions, and the potential complexing of radionuclides with organic compounds and solvents which mobilize normally highly sorbable nuclides. Theoretical studies of digital predictive solute transport models are being implemented to assure their availability for application to problems and processes identified in the field and laboratory. ?? 1976 International Association of Engineering Geology.

75 FR 76038 - Zach System Corporation a Subdivision of Zambon Company, SPA Including On-Site Leased Workers of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-07

... Subdivision of Zambon Company, SPA Including On-Site Leased Workers of Turner Industries and Go Johnson, La..., including on-site leased workers from Turner Industries and Go Johnson, La Porte, Texas. The Department's..., including on-site leased workers of Turner Industries and Go Johnson, La Porte, Texas, who became totally or...

Water-quality and biological data for selected streams, lakes, and wells in the High Point Lake watershed, Guilford County, North Carolina, 1988-89

USGS Publications Warehouse

Davenport, M.S.

1993-01-01

Water and bottom-sediment samples were collected at 26 sites in the 65-square-mile High Point Lake watershed area of Guilford County, North Carolina, from December 1988 through December 1989. Sampling locations included 10 stream sites, 8 lake sites, and 8 ground-water sites. Generally, six steady-flow samples were collected at each stream site and three storm samples were collected at five sites. Four lake samples and eight ground-water samples also were collected. Chemical analyses of stream and lake sediments and particle-size analyses of lake sediments were performed once during the study. Most stream and lake samples were analyzed for field characteristics, nutrients, major ions, trace elements, total organic carbon, and chemical-oxygen demand. Analyses were performed to detect concentrations of 149 selected organic compounds, including acid and base/neutral extractable and volatile constituents and carbamate, chlorophenoxy acid, triazine, organochlorine, and organophosphorus pesticides and herbicides. Selected lake samples were analyzed for all constituents listed in the Safe Drinking Water Act of 1986, including Giardia, Legionella, radiochemicals, asbestos, and viruses. Various chromatograms from organic analyses were submitted to computerized library searches. The results of these and all other analyses presented in this report are in tabular form.

Surgical Site Infiltration for Abdominal Surgery: A Novel Neuroanatomical-based Approach

PubMed Central

Janis, Jeffrey E.; Haas, Eric M.; Ramshaw, Bruce J.; Nihira, Mikio A.; Dunkin, Brian J.

2016-01-01

Background: Provision of optimal postoperative analgesia should facilitate postoperative ambulation and rehabilitation. An optimal multimodal analgesia technique would include the use of nonopioid analgesics, including local/regional analgesic techniques such as surgical site local anesthetic infiltration. This article presents a novel approach to surgical site infiltration techniques for abdominal surgery based upon neuroanatomy. Methods: Literature searches were conducted for studies reporting the neuroanatomical sources of pain after abdominal surgery. Also, studies identified by preceding search were reviewed for relevant publications and manually retrieved. Results: Based on neuroanatomy, an optimal surgical site infiltration technique would consist of systematic, extensive, meticulous administration of local anesthetic into the peritoneum (or preperitoneum), subfascial, and subdermal tissue planes. The volume of local anesthetic would depend on the size of the incision such that 1 to 1.5 mL is injected every 1 to 2 cm of surgical incision per layer. It is best to infiltrate with a 22-gauge, 1.5-inch needle. The needle is inserted approximately 0.5 to 1 cm into the tissue plane, and local anesthetic solution is injected while slowly withdrawing the needle, which should reduce the risk of intravascular injection. Conclusions: Meticulous, systematic, and extensive surgical site local anesthetic infiltration in the various tissue planes including the peritoneal, musculofascial, and subdermal tissues, where pain foci originate, provides excellent postoperative pain relief. This approach should be combined with use of other nonopioid analgesics with opioids reserved for rescue. Further well-designed studies are necessary to assess the analgesic efficacy of the proposed infiltration technique. PMID:28293525

The Long-Term Safety of S-Flurbiprofen Plaster for Osteoarthritis Patients: An Open-Label, 52-Week Study.

PubMed

Yataba, Ikuko; Otsuka, Noboru; Matsushita, Isao; Matsumoto, Hideo; Hoshino, Yuichi

2016-08-01

The newly developed S-flurbiprofen plaster (SFPP) is a tape-type patch that shows innovative percutaneous absorption. This study was designed to evaluate the safety of a long-term 52-week SFPP application to osteoarthritis (OA) patients. This was a multi-center, open-label, uncontrolled prospective study that included 201 OA patients. SFPP at 40 mg/day was applied to the site of pain in 101 patients and at 80 mg/day (2 patches) in 100 patients at a total of 301 sites for 52 weeks. The affected sites assessed included the knee (192), lumbar spine (66), cervical spine (26), and others (17). Drug safety was evaluated by medical examination, laboratory tests, and examination of vital signs. Efficacy was evaluated by the patient's and clinician's global assessments and clinical symptoms. Most patients (80.1 %) completed the 52-week SFPP application. The majority of drug-related adverse events (AEs) included mild dermatitis at the application sites and occurred in 46.8 % of the sites. No photosensitive dermatitis was observed. Systemic AEs occurred in 9.0 % of the patients; a serious AE (gastric ulcer hemorrhage) occurred in one patient. No clinically significant changes in the laboratory tests and vital signs were observed. The efficacy evaluation showed an improvement from 2 weeks after the SFPP application, which continued during the 52 weeks' treatment. No apparent safety concerns were observed, even during the long-term SFPP application. Therefore, SFPP could be an additional pharmacotherapy in OA treatment.

Prospective study of DNA methylation at chromosome 8q24 in peripheral blood and prostate cancer risk.

PubMed

Barry, Kathryn Hughes; Moore, Lee E; Sampson, Joshua N; Koutros, Stella; Yan, Liying; Meyer, Ann; Reddy, Mahitha; Oler, Andrew J; Cook, Michael B; Fraumeni, Joseph F; Yeager, Meredith; Amundadottir, Laufey T; Berndt, Sonja I

2017-05-23

Chromosome 8q24 has emerged as an important genetic susceptibility region for several cancers, including prostate cancer; however, little is known about the contribution of DNA methylation in this region to risk. We prospectively evaluated DNA methylation at 8q24 in relation to prostate cancer using pre-diagnostic blood samples from 694 prostate cancer cases (including 172 aggressive cases) and 703 controls in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. We used logistic regression to estimate odds ratios and 95% confidence intervals. Although none remained significant after adjustment for multiple testing (q>0.05), of the 50 CpG sites meeting quality control, we identified 8 sites that were nominally associated with prostate cancer (P trend <0.05), including 6 correlated (Spearman ρ: 0.20-0.52) sites in POU5F1B and 2 intergenic sites (most significant site: Chr8:128428897 in POU5F1B, P trend =0.01). We also identified two correlated (ρ=0.39) sites in MYC (Chr8:128753187 and Chr8:128753154) that were associated with aggressive (P trend =0.02 and 0.03), but not non-aggressive disease (P trend =0.70 and 0.20; P heterogeneity =0.01 and 4.6 × 10 -3 ). These findings persisted after adjustment for the top 8q24 prostate cancer variants in our study. Although requiring replication, our findings provide some evidence that 8q24 DNA methylation levels may be associated with prostate cancer risk.

Experience in Grid Site Testing for ATLAS, CMS and LHCb with HammerCloud

NASA Astrophysics Data System (ADS)

Elmsheuser, Johannes; Medrano Llamas, Ramón; Legger, Federica; Sciabà, Andrea; Sciacca, Gianfranco; Úbeda García, Mario; van der Ster, Daniel

2012-12-01

Frequent validation and stress testing of the network, storage and CPU resources of a grid site is essential to achieve high performance and reliability. HammerCloud was previously introduced with the goals of enabling VO- and site-administrators to run such tests in an automated or on-demand manner. The ATLAS, CMS and LHCb experiments have all developed VO plugins for the service and have successfully integrated it into their grid operations infrastructures. This work will present the experience in running HammerCloud at full scale for more than 3 years and present solutions to the scalability issues faced by the service. First, we will show the particular challenges faced when integrating with CMS and LHCb offline computing, including customized dashboards to show site validation reports for the VOs and a new API to tightly integrate with the LHCbDIRAC Resource Status System. Next, a study of the automatic site exclusion component used by ATLAS will be presented along with results for tuning the exclusion policies. A study of the historical test results for ATLAS, CMS and LHCb will be presented, including comparisons between the experiments’ grid availabilities and a search for site-based or temporal failure correlations. Finally, we will look to future plans that will allow users to gain new insights into the test results; these include developments to allow increased testing concurrency, increased scale in the number of metrics recorded per test job (up to hundreds), and increased scale in the historical job information (up to many millions of jobs per VO).

Impact of informal electronic waste recycling on metal concentrations in soils and dusts.

PubMed

Ohajinwa, Chimere May; van Bodegom, Peter M; Vijver, Martina G; Peijnenburg, Willie J G M

2018-07-01

Electronic and electrical equipment contains over 1000 different substances, including metals. During informal e-waste recycling some of these substances such as metals, are released into the environment causing environmental pollution. This study assessed the impact of different informal e-waste recycling activities (burning, dismantling, and repairing) on metal concentrations in top soils and various dust. A comparative cross-sectional study design was adopted to assess metal concentrations in top soils and in various dust samples from multiple e-waste recycling sites. Metal concentrations at e-waste recycling sites were compared to the concentrations at control sites in three study locations in Nigeria (Lagos, Ibadan, and Aba). In the three study locations, mean metal concentrations at the e-waste recycling sites exceeded the concentrations at the control sites and the Nigerian standard guideline values by 100 s to 1000 s times. Burning sites showed the highest pollution level, followed by dismantling sites, then repair sites. Our findings show serious environmental and public health concerns. The metal concentrations were also higher than levels reported in other studies at the same locations in Nigeria, indicating that the situation is worsening. This study provides scientific evidence for an urgent need to develop effective strategies to strengthen enforcement of existing e-waste regulations in Nigeria. Copyright © 2018 Elsevier Inc. All rights reserved.

Natural Areas Analysis and Evaluation: Oak Ridge Reservation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baranski, Micahel J

EXECUTIVE SUMMARY The Oak Ridge Reservation, encompassing 33,639 acres in the Valley and Ridge Physiographic Province of East Tennessee, has long been known for its unfragmented forests and high biodiversity. Many areas on the Reservation have been recognized as important natural areas, but no comprehensive treatment has been performed to evaluate the relative significance and importance of these areas compared to each other. The present study was conducted to develop a set of guidelines for evaluating the natural value of specific areas, to evaluate all the terrestrial areas that are currently delineated, and to rank all areas according to theirmore » relative biodiversity importance. All available data, reports and site-specific information relevant to Reservation lands, including Tennessee Division of Natural Areas database information, were evaluated and field work was conducted. Methodologies and criteria for assessment and evaluation of areas were developed; categories of criteria were devised; and a ranking system for evaluation of natural areas was produced. There were 70 areas evaluated during the study. The system is flexible, dynamic and easily revised to reflect updated and new information and interpretations. Eight categories of evaluation factors were established and used to characterize each site. These were the following: size of area, number or status taxa present, number of Endangered and Threatened taxa present, rarity of the Endangered and Threatened taxa on the Reservation, community diversity, site integrity and quality, disturbance and threat levels, and other significant features and factors. Each category generally consisted of a 5-point ranking scale from 0-4, allowing for a possible composite score of 32, with higher ranked, more important, sites attaining higher scores. Highly ranked sites are representative of regional natural diversity; contain outstanding natural features, communities or geology and/or very rare taxa or other elements; are relatively large in size with mature or old-growth community composition; lack current disturbance factors or potential threats and disturbances; are in excellent condition with good buffers; are places where ecological and evolutionary processes can occur relatively unaffected by humans; and can be reasonably defended and maintained as natural areas in an undeveloped condition. Highly ranked sites are the most significant and should receive the greatest protections. Composite scores of the ranked areas ranged from 1-25.5, with a mean score of 12. The ranked areas were divided into three Priority Groups. Group I, the most highly ranked group, included 20 sites and covered 5189 acres or 15.4% of Reservation lands; Group II included 31 sites and covered 4108 acres; Group III included 19 sites covering 400 acres of Reservation lands. All sites together comprise 9697 acres or 28.8% of Reservation lands. Six sites emerged as clearly the most significant natural areas on the Reservation. The study developed a number of recommendations that should be implemented in order to enhance and refine the natural areas data for the Reservation. There is a clear need for better and standardized ecological community classification and identification. Several areas are proposed for merger into larger units, and some new areas are proposed for inclusion and recognition in a natural areas system. Various gaps and discrepancies in the existing data are described and should be corrected. Other recommendations are made, including the development of a corollary system that can accommodate aquatic natural areas. The study relied primarily on the synthesis of information from many sources and from limited reconnaissance and direct observation during field work to produce a methodology for assessing natural area importance and assigning priorities for protection. Many instances of incomplete, missing or conflicting information made it difficult to complete thorough analysis. Further review and discussion among natural resources personnel will likely reveal possibilities for refinement and some additional factors that should be included in the evaluation. Despite the limitations, this study, as conducted, illustrates the importance of the Oak Ridge Reservation for protecting the nation s increasingly threatened and declining biodiversity.« less

Hydrologic data from the study of acidic contamination in the Miami Wash-Pinal Creek area, Arizona, water years 1992-93

USGS Publications Warehouse

Gellenbeck, D.J.; Hunter, Yvonne R.

1994-01-01

Since 1984, hydrologic data have been collected as part of a U.S. Geological Survey study of the occurrence and movement of acidic contamination in the aquifer and streams of the Pinal Creek drainage basin near Globe, Arizona. Ground-water data from that study are presented for water years 1992 and 1993 and include location, construction information, site plans, water levels, chemical and physical field measurements, and selected chemical analyses of water samples for 10 monitoring well groups. During January 1993, a flood occurred in Pinal Creek that resulted in a record peak discharge of 5,700 cubic feet per second. During this flood, well group 450 was destroyed. Surface-water data are presented for 13 sites and include discharge measurements, chemical and physical field measure- ments, and chemical analyses of water. Data from a solute-transport study that was conducted in November 1992 are presented for shallow ground-water and surface-water sites along Pinal Creek. During this study, variations in metal chemistry with distance along Pinal Creek and depth below the streambed were determined and two filter sizes were used to quantify the partitioning of metals between dissolved and particulate phases. Monthly precipi- tation data and long-term precipitation statistics are presented for two sites.

Time Spent on Social Network Sites and Psychological Well-Being: A Meta-Analysis.

PubMed

Huang, Chiungjung

2017-06-01

This meta-analysis examines the relationship between time spent on social networking sites and psychological well-being factors, namely self-esteem, life satisfaction, loneliness, and depression. Sixty-one studies consisting of 67 independent samples involving 19,652 participants were identified. The mean correlation between time spent on social networking sites and psychological well-being was low at r = -0.07. The correlations between time spent on social networking sites and positive indicators (self-esteem and life satisfaction) were close to 0, whereas those between time spent on social networking sites and negative indicators (depression and loneliness) were weak. The effects of publication outlet, site on which users spent time, scale of time spent, and participant age and gender were not significant. As most included studies used student samples, future research should be conducted to examine this relationship for adults.

Ecological Restoration: Bringing Back the Prairie.

ERIC Educational Resources Information Center

Murray, Molly Fifield

1997-01-01

Defines ecological restoration and offers a plan for prairie restoration as a schoolyard project. Steps include researching and planning the site, preparation and planting, and continuing management of the site. Ecological concepts in this activity also relate to science, language arts, math, social studies, art, and music for K-12 students. (AIM)

Checking Studies on Zones of Siting Feasibility for Dredged Material in Puget Sound.

DTIC Science & Technology

1986-01-01

priority pollutants in the ZSFs including copper, lead, mercury , HPAH, LPAH, PCBs and DDT. The area around Fourmile Rock dump site was classified in a...sediment contains ferric hydroxide (an olive color when associated with organic particles), while the reduced hydrogen sulphide sediments below this

A Guide to Ohio Outdoor Education Areas.

ERIC Educational Resources Information Center

Melvin, Ruth W.

More than 700 areas in Ohio, useful as sites for environmental and outdoor studies, are catalogued in this guide. They include national forests; state parks; forest and wildlife areas; historic sites and memorials; metropolitan, country, and city parks; agency and private camps; conservation agency properties; conservancy district lands and…

Consumer Response to Web Sites and Their Influence on Advertising Effectiveness.

ERIC Educational Resources Information Center

Goldsmith, Ronald E.; Lafferty, Barbara A.

2002-01-01

Describes a study of undergraduates that tested four hypotheses regarding the effects of viewing Web sites on Internet advertising. Highlights include attitudes toward ads in marketing communications and advertising research; recalling brand names seen on the Internet; perceived advantages and disadvantages of online advertising; and recalling ads…

Repeat 24-hour recalls and locally developed food composition databases: a feasible method to estimate dietary adequacy in a multi-site preconception maternal nutrition RCT

PubMed Central

Lander, Rebecca L.; Hambidge, K. Michael; Krebs, Nancy F.; Westcott, Jamie E.; Garces, Ana; Figueroa, Lester; Tejeda, Gabriela; Lokangaka, Adrien; Diba, Tshilenge S.; Somannavar, Manjunath S.; Honnayya, Ranjitha; Ali, Sumera A.; Khan, Umber S.; McClure, Elizabeth M.; Thorsten, Vanessa R.; Stolka, Kristen B.

2017-01-01

ABSTRACT Background: Our aim was to utilize a feasible quantitative methodology to estimate the dietary adequacy of >900 first-trimester pregnant women in poor rural areas of the Democratic Republic of the Congo, Guatemala, India and Pakistan. This paper outlines the dietary methods used. Methods: Local nutritionists were trained at the sites by the lead study nutritionist and received ongoing mentoring throughout the study. Training topics focused on the standardized conduct of repeat multiple-pass 24-hr dietary recalls, including interview techniques, estimation of portion sizes, and construction of a unique site-specific food composition database (FCDB). Each FCDB was based on 13 food groups and included values for moisture, energy, 20 nutrients (i.e. macro- and micronutrients), and phytate (an anti-nutrient). Nutrient values for individual foods or beverages were taken from recently developed FAO-supported regional food composition tables or the USDA national nutrient database. Appropriate adjustments for differences in moisture and application of nutrient retention and yield factors after cooking were applied, as needed. Generic recipes for mixed dishes consumed by the study population were compiled at each site, followed by calculation of a median recipe per 100 g. Each recipe’s nutrient values were included in the FCDB. Final site FCDB checks were planned according to FAO/INFOODS guidelines. Discussion: This dietary strategy provides the opportunity to assess estimated mean group usual energy and nutrient intakes and estimated prevalence of the population ‘at risk’ of inadequate intakes in first-trimester pregnant women living in four low- and middle-income countries. While challenges and limitations exist, this methodology demonstrates the practical application of a quantitative dietary strategy for a large international multi-site nutrition trial, providing within- and between-site comparisons. Moreover, it provides an excellent opportunity for local capacity building and each site FCDB can be easily modified for additional research activities conducted in other populations living in the same area. PMID:28469549

Assessing technical performance at diverse ambulatory care sites.

PubMed

Osterweis, M; Bryant, E

1978-01-01

The purpose of the large study reported here was to develop and test methods for assessing the quality of health care that would be broadly applicable to diverse ambulatory care organizations for periodic comparative review. Methodological features included the use of an age-sex stratified random sampling scheme, dependence on medical records as the source of data, a fixed study period year, use of Kessner's tracer methodology (including not only acute and chronic diseases but also screening and immunization rates as indicators), and a fixed tracer matrix at all test sites. This combination of methods proved more efficacious in estimating certain parameters for the total patient populations at each site (including utilization patterns, screening, and immunization rates) and the process of care for acute conditions than it did in examining the process of care for the selected chronic condition. It was found that the actual process of care at all three sites for the three acute conditions (streptococcal pharyngitis, urinary tract infection, and iron deficiency anemia) often differed from the expected process in terms of both diagnostic procedures and treatment. For hypertension, the chronic disease tracer, medical records were frequently a deficient data source from which to draw conclusions about the adequacy of treatment. Several aspects of the study methodology were found to be detrimental to between-site comparisons of the process of care for chronic disease management. The use of an age-sex stratified random sampling scheme resulted in the identification of too few cases of hypertension at some sites for analytic purposes, thereby necessitating supplementary sampling by diagnosis. The use of a fixed study period year resulted in an arbitrary starting point in the course of the disease. Furthermore, in light of the diverse sociodemographic characteristics of the patient populations, the use of a fixed matrix of tracer conditions for all test sites is questionable. The discussion centers on these and other problems encountered in attempting to compare technical performance within diverse ambulatory care organizations and provides some guidelines as to the utility of alternative methods for assessing the quality of health care.

Studies in Phlebotomine Sand Flies.

DTIC Science & Technology

1982-06-30

Phlebotomus duboscqi, a vector of cutaneous leishmaniasis, was developed in Kenya at a site where Leishmania major has been isolated from rodents , A...fauna. Addi- tional species, including 2 undescribed taxa, were studied from Ecuador, Peru and Surinam. The reference collection of New World...was discovered in Kenya at a site where Leishmania a has been isolated from rodents . A paper describing the previously unknown male of Sergentomyia

United States Air Force 611th Air Support Group/Civil Engineering Squadron, Elmendorf AFB, Alaska. Remedial investigation and feasibility study: Oliktok Point Radar Installation, Alaska. Volume 1. (Includes appendices a - b)

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-04-15

This report presents the findings of Remedial Investigations and Feasibility Studies at sites located at the Oliktok Point radar installation in northern Alaska. The sites were characterized based on sampling and analyses conducted during Remedial Investigation activities performed during August and September 1993.

Environmental Fate and Exposure Assessment for Arsenic in Groundwater

DTIC Science & Technology

2008-08-01

The Devens study suggests that MNA may be an effective remedial option for sites where naturally-occurring arsenic has been mobilized due to...The Devens study suggests that MNA may be an effective remedial option for sites where naturally-occurring arsenic has been mobilized due to...per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing

Water-quality assessment of south-central Texas: Occurrence and distribution of volatile organic compounds in surface water and ground water, 1983-94, and implications for future monitoring

USGS Publications Warehouse

Ging, P.B.; Judd, L.J.; Wynn, K.H.

1997-01-01

The study area of the South-Central Texas study unit of the National Water-Quality Assessment Program comprises the Edwards aquifer in the San Antonio region and its catchment area. The first phase of the assessment includes evaluation of existing water-quality data for surface water and ground water, including volatile organic compounds, to determine the scope of planned monitoring. Most analyses of volatile organic compounds in surface water are from the National Pollutant Discharge Elimination System sites in San Antonio, Texas. Nine volatile organic compounds were detected at the six sites. The three compounds with the most detections at National Pollutant Discharge Elimination System sites are 1,2,4-trimethylbenzene, toluene, and xylene. Analysis of volatile organic compounds in ground water was limited to Edwards aquifer wells. Twenty-eight volatile organic compounds were detected in samples from 89 wells. The five most commonly detected compounds in samples from wells, in descending order, are tetrachloroethene, trichloroethene, bromoform, chloroform, and dibromochloromethane. Detections of volatile organic compounds in surface water and ground water within the South-Central Texas study area are limited to site-specific sources associated with development; therefore, planned monitoring for possible detections of volatile organic compounds as part of the National Water-Quality Assessment Program will emphasize areas of expanding population and development. Monitoring of volatile organic compounds is planned at National Pollutant Discharge Elimination System sites, at basic fixed surface-water sites, and in the ground-water study-unit surveys.

Communication of Career Pathways Through Associate Degree Program Web Sites: A Baseline Assessment.

PubMed

Becker, Ellen A; Vargas, Jenny

2018-05-08

The American Association for Respiratory Care sponsored a series of conferences that addressed the competency of the future workforce of respiratory therapists (RTs). Based upon the findings from those conferences, several initiatives emerged that support RTs earning a baccalaureate (or bachelor's) degree. The objective of this study was to identify the ways that associate degree programs communicate career pathways toward a baccalaureate degree through their Web sites. This cross-sectional observational study used a random sample of 100 of the 362 associate degree programs approved by the Commission on Accreditation for Respiratory Care. Data were collected from 3 specific categories: demographic data, baccalaureate completion information, and the Web page location for the program. The presence of statements related to any pathway toward a bachelor's degree, transfer credits, articulation agreements, and links for baccalaureate completion were recorded. The descriptive statistics in this study were reported as total numbers and percentages. Of the 100 programs in the random sample, only 89 were included in the study. Only 39 (44%) programs had links on their program Web site that had any content related to bachelor's degrees, 16 (18%) identified college transfer courses toward a bachelor's degree, and 26 (29%) programs included baccalaureate articulation agreements on their Web site. A minority of associate degree programs communicated career pathway information to their prospective and current students through program Web sites. An informative Web site would make the path more transparent for entry-level students to meet their future educational needs as their careers progress. Copyright © 2018 by Daedalus Enterprises.

Early results from a multi-component French public-private partnership initiative to improve participation in clinical research - CeNGEPS: a prospective before-after study.

PubMed

Bordet, Régis; Lang, Marie; Dieu, Christelle; Billon, Nathalie; Duffet, Jean-Pierre

2015-08-19

A public-private (51/49 %) partnership was initiated in 2007 in France to improve the attractiveness of French sites in industry-sponsored international clinical trials. This initiative developed and implemented a combination of structuring actions and support actions. Here we report the assessment of the impact after 6 years on participation of French study sites in industry-sponsored clinical trials. We performed a prospective before-after study of clinical research activities in French public hospitals to assess the impact of actions developed and implemented by CeNGEPS. The programme involved a combination of structuring actions (establishment of sites of excellence, national networks and dedicated clinical research assistants (CRAs)), support actions (tools, templates and training) and competitive budget allocation for sites or networks based on performance. The impact was assessed using the following performance criteria: 1) reduction of the delay to contract signature to ≤ 60 days for 80 % of the trial sites; 2) inclusion of ≥80 % of the planned number of patients by at least 80 % of trial sites; 3) closure of <15 % of trials sites without patients enrolled. In 2013, the median delay to contract signature was: 55 days, compared with 76 days in 2008 (27.6 % reduction), 50.5 % of all sites and 58 % of sites with a dedicated CRA included ≥80 % of the planned number of patients compared with 44.8 % in 2008 (12.7 % increase) and 21.3 % of all sites and 9 % of sites with a dedicated CRA closed with no patients included, compared with 26.4 % in 2008 (19.3 and 65.9 %, respectively). These results provide evidence that it is possible to improve a country's attractiveness for industry-sponsored clinical research. The two main actions, i.e. establishing sites of excellence throughout the country with well-trained, dedicated staff and establishing a national network of clinical investigators, could be adapted to other countries in Western Europe to improve Europe's attractiveness to industry-funded trials.

Pharmaceuticals and other organic chemicals in selected north-central and northwestern Arkansas streams

USGS Publications Warehouse

Haggard, B.E.; Galloway, J.M.; Green, W.R.; Meyer, M.T.

2006-01-01

Recently, our attention has focused on the low level detection of many antibiotics, pharmaceuticals, and other organic chemicals in water resources. The limited studies available suggest that urban or rural streams receiving wastewater effluent are more susceptible to contamination. The purpose of this study was to evaluate the occurrence of antibiotics, pharmaceuticals, and other organic chemicals at 18 sites on seven selected streams in Arkansas, USA, during March, April, and August 2004. Water samples were collected upstream and downstream from the influence of effluent discharges in northwestern Arkansas and at one site on a relatively undeveloped stream in north-central Arkansas. At least one antibiotic, pharmaceutical, or other organic chemical was detected at all sites, except at Spavinaw Creek near Mayesville, Arkansas. The greatest number of detections was observed at Mud Creek downstream from an effluent discharge, including 31 pharmaceuticals and other organic chemicals. The detection of these chemicals occurred in higher frequency at sites downstream from effluent discharges compared to those sites upstream from effluent discharges; total chemical concentration was also greater downstream. Wastewater effluent discharge increased the concentrations of detergent metabolites, fire retardants, fragrances and flavors, and steroids in these streams. Antibiotics and associated degradation products were only found at two streams downstream from effluent discharges. Overall, 42 of the 108 chemicals targeted in this study were found in water samples from at least one site, and the most frequently detected organic chemicals included caffeine, phenol, para-cresol, and acetyl hexamethyl tetrahydro naphthalene (AHTN). ?? ASA, CSSA, SSSA.

Public health assessment for Rockwool Industries, Belton, Bell County, Texas, Region 6, CERCLIS number TXD066379645. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1999-08-03

The Rockwool Industries, Inc. (RWI) National Priorities List site is a 100 acre site one-mile east of downtown Belton in Bell County, Texas. The Facility manufactured two types of mineral wool insulation: Blow wool and batt wool. Three main contaminant source areas have been identified at the site. Source 1, in the middle portion of the site, includes contaminated soil associated with the South Shot Pile. Source 2, in the northern portion of the site, includes contaminated soils associated with the Cemetery Shot Pile. Source 3, in the northwest portion of the site includes contaminated soils associated with the Cemeterymore » Shot Pile. The primary waste types at the site include spent iron shot and baghouse dust. Secondary waste types include boiler blowdown water, stormwater runoff, recovered groundwater, and bricks. The Texas Department of Health (TDH) and the Agency for Toxic Substances and Disease Registry (ATSDR) evaluated the environmental information available for the site and identified several exposure situations for evaluation. These exposure situations include possible contact with site contaminants in the soil, surface water, sediment, and groundwater. The potential for exposure to site contaminants through the food chain was also examined. A brief review of the evaluation, organized by hazard category, is presented.« less

The occurrence of Simpson's paradox if site-level effect was ignored in the TREAT Asia HIV Observational Database.

PubMed

Jiamsakul, Awachana; Kerr, Stephen J; Chandrasekaran, Ezhilarasi; Huelgas, Aizobelle; Taecharoenkul, Sineenart; Teeraananchai, Sirinya; Wan, Gang; Ly, Penh Sun; Kiertiburanakul, Sasisopin; Law, Matthew

2016-08-01

In multisite human immunodeficiency virus (HIV) observational cohorts, clustering of observations often occurs within sites. Ignoring clustering may lead to "Simpson's paradox" (SP) where the trend observed in the aggregated data is reversed when the groups are separated. This study aimed to investigate the SP in an Asian HIV cohort and the effects of site-level adjustment through various Cox regression models. Survival time from combination antiretroviral therapy (cART) initiation was analyzed using four Cox models: (1) no site adjustment; (2) site as a fixed effect; (3) stratification through site; and (4) shared frailty on site. A total of 6,454 patients were included from 23 sites in Asia. SP was evident in the year of cART initiation variable. Model (1) shows the hazard ratio (HR) for years 2010-2014 was higher than the HR for 2006-2009, compared to 2003-2005 (HR = 0.68 vs. 0.61). Models (2)-(4) consistently implied greater improvement in survival for those who initiated in 2010-2014 than 2006-2009 contrasting findings from model (1). The effects of other significant covariates on survival were similar across four models. Ignoring site can lead to SP causing reversal of treatment effects. Greater emphasis should be made to include site in survival models when possible. Copyright © 2016 Elsevier Inc. All rights reserved.

A survey of health-related activities on second life.

PubMed

Beard, Leslie; Wilson, Kumanan; Morra, Dante; Keelan, Jennifer

2009-05-22

Increasingly, governments, health care agencies, companies, and private groups have chosen Second Life as part of their Web 2.0 communication strategies. Second Life offers unique design features for disseminating health information, training health professionals, and enabling patient education for both academic and commercial health behavior research. This study aimed to survey and categorize the range of health-related activities on Second Life; to examine the design attributes of the most innovative and popular sites; and to assess the potential utility of Second Life for the dissemination of health information and for health behavior change. We used three separate search strategies to identify health-related sites on Second Life. The first used the application's search engine, entering both generic and select illness-specific keywords, to seek out sites. The second identified sites through a comprehensive review of print, blog, and media sources discussing health activities on Second Life. We then visited each site and used a snowball method to identify other health sites until we reached saturation (no new health sites were identified). The content, user experience, and chief purpose of each site were tabulated as well as basic site information, including user traffic data and site size. We found a wide range of health-related activities on Second Life, and a diverse group of users, including organizations, groups, and individuals. For many users, Second Life activities are a part of their Web 2.0 communication strategy. The most common type of health-related site in our sample (n = 68) were those whose principle aim was patient education or to increase awareness about health issues. The second most common type of site were support sites, followed by training sites, and marketing sites. Finally, a few sites were purpose-built to conduct research in SL or to recruit participants for real-life research. Studies show that behaviors from virtual worlds can translate to the real world. Our survey suggests that users are engaged in a range of health-related activities in Second Life which are potentially impacting real-life behaviors. Further research evaluating the impact of health-related activities on Second Life is warranted.

A Survey of Health-Related Activities on Second Life

PubMed Central

Beard, Leslie; Wilson, Kumanan; Morra, Dante

2009-01-01

Background Increasingly, governments, health care agencies, companies, and private groups have chosen Second Life as part of their Web 2.0 communication strategies. Second Life offers unique design features for disseminating health information, training health professionals, and enabling patient education for both academic and commercial health behavior research. Objectives This study aimed to survey and categorize the range of health-related activities on Second Life; to examine the design attributes of the most innovative and popular sites; and to assess the potential utility of Second Life for the dissemination of health information and for health behavior change. Methods We used three separate search strategies to identify health-related sites on Second Life. The first used the application’s search engine, entering both generic and select illness-specific keywords, to seek out sites. The second identified sites through a comprehensive review of print, blog, and media sources discussing health activities on Second Life. We then visited each site and used a snowball method to identify other health sites until we reached saturation (no new health sites were identified). The content, user experience, and chief purpose of each site were tabulated as well as basic site information, including user traffic data and site size. Results We found a wide range of health-related activities on Second Life, and a diverse group of users, including organizations, groups, and individuals. For many users, Second Life activities are a part of their Web 2.0 communication strategy. The most common type of health-related site in our sample (n = 68) were those whose principle aim was patient education or to increase awareness about health issues. The second most common type of site were support sites, followed by training sites, and marketing sites. Finally, a few sites were purpose-built to conduct research in SL or to recruit participants for real-life research. Conclusions Studies show that behaviors from virtual worlds can translate to the real world. Our survey suggests that users are engaged in a range of health-related activities in Second Life which are potentially impacting real-life behaviors. Further research evaluating the impact of health-related activities on Second Life is warranted. PMID:19632971

[To evaluate the quality of life and peristomal skin ostomy patient with the new device Sensura].

PubMed

Crespo Fontán, Beatriz; Caparrós Sanz, María Rosario; Lainez Pardos, Pilar Lourdes; Davín Durban, Inmaculada

2010-10-01

In 2006, Coloplast launched in several European countries a new device for ostomy care called Sensura. This clinical research report includes only the results of the subpopulation included in Spain as a part of an international study involving many countries such as Denmark, United States, Canada, Australia, Poland, Netherlands, France, Slovakia, Germany, UK, Italy, Iceland, Japan, Czech Republic, Portugal, South Korea and Argentina. OBJECTIVES AND STUDY VARIABLES: The main purpose of the study is to evaluate the experience with Sensura, under normal conditions of use, with special attention to skin condition and quality of life. The main objective of the study is to evaluate the quality of life, through Quality of Life Questionnaire called "Stoma QoL". A secondary objective, is to study the correlation between quality of life and the peristomal skin condition. Other Secondary objectives include the evaluation of the patient's current device at the time of entering the study and by the other hand, the device Sensura and safety evaluation throughout the study. The study was designed as an open label non-comparative, multi-national Post Market study. The study period for each patient is 6 to 8 weeks +/- 4 days, which includes an initial visit and a final visit. The study population included people who carry a colostomy or ileostomy. Regarding Spain, a total of 10 sites participated and included a total of 131 patients. This report only presents results for nine sites and a total of 123 patients. The reason is that the last participating site began the study with a considerable delay The remaining subjects included in this site together with the other centers in Spain and the other participating countries will be included in the final international report, that will present the overall results. MEASUREMENT TOOLS. Stoma-QoL (Quality of Life Questionnaire for people with an ostomy). OST (Ostomy Skin Tool) instrument for the assessment of peristomal skin. As for the quality of life, at baseline we found a mean of 59 out of 100 (SD = 8.8), while the final study visit, mean score was 59.6 out of 100 (SD = 9.3), although the final results on this variable will be presented in the global report, since it has not reached sufficient population in Spain for the analysis of this variable. The study revealed a significant improvement in the peristomal skin condition at the end of the study, measured by the tool OST (Ostomy Skin Tool). Regarding the evaluation of the SenSura device, there was a significant improvement related to the appearance of leakage of effluent, as well as other items evaluated in relation with the device.

The precision of wet atmospheric deposition data from national atmospheric deposition program/national trends network sites determined with collocated samplers

USGS Publications Warehouse

Nilles, M.A.; Gordon, J.D.; Schroder, L.J.

1994-01-01

A collocated, wet-deposition sampler program has been operated since October 1988 by the U.S. Geological Survey to estimate the overall sampling precision of wet atmospheric deposition data collected at selected sites in the National Atmospheric Deposition Program and National Trends Network (NADP/NTN). A duplicate set of wet-deposition sampling instruments was installed adjacent to existing sampling instruments at four different NADP/NTN sites for each year of the study. Wet-deposition samples from collocated sites were collected and analysed using standard NADP/NTN procedures. Laboratory analyses included determinations of pH, specific conductance, and concentrations of major cations and anions. The estimates of precision included all variability in the data-collection system, from the point of sample collection through storage in the NADP/NTN database. Sampling precision was determined from the absolute value of differences in the analytical results for the paired samples in terms of median relative and absolute difference. The median relative difference for Mg2+, Na+, K+ and NH4+ concentration and deposition was quite variable between sites and exceeded 10% at most sites. Relative error for analytes whose concentrations typically approached laboratory method detection limits were greater than for analytes that did not typically approach detection limits. The median relative difference for SO42- and NO3- concentration, specific conductance, and sample volume at all sites was less than 7%. Precision for H+ concentration and deposition ranged from less than 10% at sites with typically high levels of H+ concentration to greater than 30% at sites with low H+ concentration. Median difference for analyte concentration and deposition was typically 1.5-2-times greater for samples collected during the winter than during other seasons at two northern sites. Likewise, the median relative difference in sample volume for winter samples was more than double the annual median relative difference at the two northern sites. Bias accounted for less than 25% of the collocated variability in analyte concentration and deposition from weekly collocated precipitation samples at most sites.A collocated, wet-deposition sampler program has been operated since OCtober 1988 by the U.S Geological Survey to estimate the overall sampling precision of wet atmospheric deposition data collected at selected sites in the National Atmospheric Deposition Program and National Trends Network (NADP/NTN). A duplicate set of wet-deposition sampling instruments was installed adjacent to existing sampling instruments four different NADP/NTN sites for each year of the study. Wet-deposition samples from collocated sites were collected and analysed using standard NADP/NTN procedures. Laboratory analyses included determinations of pH, specific conductance, and concentrations of major cations and anions. The estimates of precision included all variability in the data-collection system, from the point of sample collection through storage in the NADP/NTN database.

Current Neonatal Skin Care Practices in Four African Sites.

PubMed

Amare, Yared; Shamba, Donat D; Manzi, Fatuma; Bee, Margaret H; Omotara, Babatunji A; Iganus, Ruth B; Adejuyigbe, Ebunoluwa A; Odebiyi, Adetanwa L; Skordis-Worrall, Jolene; Hill, Zelee E

2015-12-01

Data for this study on skin care practices and emollient use in four African sites were collected using in-depth interviews, focus-group discussions and observations. Respondents were mothers, grandmothers, fathers, health workers, birth attendants and people selling skin-care products. Analysis included content and framework analyses.Emollient use was a normative practice in all sites, with frequent application from an early age in most sites. There were variations in the type of emollients used, but reasons for use were similar and included improving the skin, keeping the baby warm, softening/strengthening the joints/bones, shaping the baby, ensuring flexibility and encouraging growth and weight gain. Factors that influenced emollient choice varied and included social pressure, cost, availability and deep-rooted traditional norms. Massage associated with application was strong and potentially damaging to the skin in some sites.Given the widespread use of emollients, the repeated exposure of newborns in the first month of life and the potential impact of emollients on mortality, trials such as those that have been conducted in Asia are needed in a range of African settings. © The Author [2015]. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Boundary conditions for the paleoenvironment: Chemical and Physical Processes in dense interstellar clouds

NASA Technical Reports Server (NTRS)

Irvine, W. M.; Schloerb, F. P.; Ziurys, L. M.

1986-01-01

The present research includes searches for important new interstellar constituents; observations relevant to differentiating between different models for the chemical processes that are important in the interstellar environment; and coordinated studies of the chemistry, physics, and dynamics of molecular clouds which are the sites or possible future sites of star formation. Recent research has included the detection and study of four new interstellar molecules; searches which have placed upper limits on the abundance of several other potential constituents of interstellar clouds; quantitative studies of comparative molecular abundances in different types of interstellar clouds; investigation of reaction pathways for astrochemistry from a comparison of theory and the observed abundance of related species such as isomers and isotopic variants; studies of possible tracers of energenic events related to star formation, including silicon and sulfur containing molecules; and mapping of physical, chemical, and dynamical properties over extended regions of nearby cold molecular clouds.

78 FR 1252 - CalAmp Wireless Networks Corporation (CWNC), Satellite Products Division, Including On-Site...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-08

... Select Staffing, Oxnard, CA; CalAmp Wireless Networks Corporation (CWNC), Including On- Site Leased... Division, including on-site leased workers from Select Staffing, Oxnard, California (TA-W-80,399). The...-site leased workers from Select Staffing, Oxnard, California (TA-W-80,399) and CalAmp Wireless Networks...

Crustal dynamics project data analysis fixed station VLBI geodetic results

NASA Technical Reports Server (NTRS)

Ryan, J. W.; Ma, C.

1985-01-01

The Goddard VLBI group reports the results of analyzing the fixed observatory VLBI data available to the Crustal Dynamics Project through the end of 1984. All POLARIS/IRIS full-day data are included. The mobile site at Platteville, Colorado is also included since its occupation bears on the study of plate stability. Data from 1980 through 1984 were used to obtain the catalog of site and radio source positions labeled S284C. Using this catalog two types of one-day solutions were made: (1) to estimate site and baseline motions; and (2) to estimate Earth rotation parameters. A priori Earth rotation parameters were interpolated to the epoch of each observation from BIH Circular D.

Interpreting forest and grassland biome productivity utilizing nested scales of image resolution and biogeographical analysis

NASA Technical Reports Server (NTRS)

Iverson, L. R.; Cook, E. A.; Graham, R. L.; Olson, J. S.; Frank, T.; Ke, Y.; Treworgy, C.; Risser, P. G.

1986-01-01

Several hardware, software, and data collection problems encountered were conquered. The Geographic Information System (GIS) data from other systems were converted to ERDAS format for incorporation with the image data. Statistical analysis of the relationship between spectral values and productivity is being pursued. Several project sites, including Jackson, Pope, Boulder, Smokies, and Huntington Forest are evolving as the most intensively studied areas, primarily due to availability of data and time. Progress with data acquisition and quality checking, more details on experimental sites, and brief summarizations of research results and future plans are discussed. Material on personnel, collaborators, facilities, site background, and meetings and publications of the investigators are included.

Physical activity and cancer risk: dose-response and cancer, all sites and site-specific.

PubMed

Thune, I; Furberg, A S

2001-06-01

The association between physical activity and overall and site-specific cancer risk is elaborated in relation to whether any observed dose-response association between physical activity and cancer can be interpreted in terms of how much physical activity (type, intensity, duration, frequency) is needed to influence site- and gender-specific cancer risk. Observational studies were reviewed that have examined the independent effect of the volume of occupational physical activity (OPA) and/or leisure time physical activity (LPA) on overall and site-specific cancer risk. The evidence of cohort and case-control studies suggests that both leisure time and occupational physical activity protect against overall cancer risk, with a graded dose-response association suggested in both sexes. Confounding effects such as diet, body weight, and parity are often included as a covariate in the analyses, with little influence on the observed associations. A crude graded inverse dose-response association was observed between physical activity and colon cancer in 48 studies including 40,674 colon/colorectal cancer cases for both sexes. A dose-response effect of physical activity on colon cancer risk was especially observed, when participation in activities of at least moderate activity (>4.5 MET) and demonstrated by activities expressed as MET-hours per week. An observed inverse association with a dose-response relationship between physical activity and breast cancer was also identified in the majority of the 41 studies including 108,031 breast cancer cases. The dose-response relationship was in particular observed in case-control studies and supported by observations in cohort studies when participation in activities of at least moderate activity (>4.5 MET) and demonstrated by activities expressed by MET-hours per week. This association between physical activity and breast cancer risk is possibly dependent on age at exposure, age at diagnosis, menopausal status and other effect modifiers, e.g., body mass index. Furthermore, data concerning carcinoma of other cancers (prostate, lung, endometrium, ovary, and testicular cancers) are required. A protective effect of physical activity on site-specific cancer risk with a dose-response association between physical activity and colon and pre- and postmenopausal breast cancer supported by identified biological mechanisms has been observed. The optimal permutation of type, intensity, duration, and frequency of physical activity across the lifespan is unclear, but it is gender, age, and site specific and supports moderate activity (>4.5 MET) more than light activities (<4.5 MET). The complicated nature of the physical activity variable, combined with lack of knowledge regarding possible biological mechanisms operating between physical activity and cancer, warrants further studies including controlled clinical randomized trials.

System-wide identification of wild-type SUMO-2 conjugation sites

PubMed Central

Hendriks, Ivo A.; D'Souza, Rochelle C.; Chang, Jer-Gung; Mann, Matthias; Vertegaal, Alfred C. O.

2015-01-01

SUMOylation is a reversible post-translational modification (PTM) regulating all nuclear processes. Identification of SUMOylation sites by mass spectrometry (MS) has been hampered by bulky tryptic fragments, which thus far necessitated the use of mutated SUMO. Here we present a SUMO-specific protease-based methodology which circumvents this problem, dubbed Protease-Reliant Identification of SUMO Modification (PRISM). PRISM allows for detection of SUMOylated proteins as well as identification of specific sites of SUMOylation while using wild-type SUMO. The method is generic and could be widely applied to study lysine PTMs. We employ PRISM in combination with high-resolution MS to identify SUMOylation sites from HeLa cells under standard growth conditions and in response to heat shock. We identified 751 wild-type SUMOylation sites on endogenous proteins, including 200 dynamic SUMO sites in response to heat shock. Thus, we have developed a method capable of quantitatively studying wild-type mammalian SUMO at the site-specific and system-wide level. PMID:26073453

Status of the flora and fauna on the Nevada Test Site, 1992. Results of continuing basic environmental monitoring, January through December 1992

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hunter, R.B.

This report documents changes in the populations of plants and animals on the Nevada Test Site (NTS) for calendar year 1992. It is part of a Department of Energy (DOE) program (Basic Environmental Compliance and Monitoring Program -- BECAMP) that also includes monitoring DOE compliance with the Endangered Species Act, the Historic Preservation Act, and the American Indian Freedom of Religion Act. Ecological studies were to comply with the National Environmental Policy Act and DOE Order 5400.1, ``General Environmental Protection Program.`` These studies focused on the following: status of ephemeral plants on the Nevada Test Site, 1992; status of reptilemore » and amphibian populations on the Nevada Test Site, 1992; trends in small mammal populations on the Nevada Test Site, 1992; status of large mammals and birds at Nevada Test Site, 1992; and status of perennial plants on the Nevada Test Site, 1992.« less

Radiocarbon in CO2 and Soil Organic Matter from Laboratory Incubations, Barrow, Alaska, 2014

DOE Data Explorer

Lydia Vaughn; Margaret Torn

2018-02-20

Dataset includes 14C measurements made from soil organic matter and CO2 from paired anaerobic and aerobic laboratory soil incubations of active layer soils collected in Barrow, Alaska in 2014. In addition to 14CO2, dataset includes CO2 production rates and carbon and nitrogen concentrations. Samples were collected from intensive study site 1 areas A, B, and C, and the site 0 and AB transects, from specified positions in high-centered, flat-centered, and low centered polygons.

Conversion of transuranic waste to low level waste by decontamination: a site specific update

DOE Office of Scientific and Technical Information (OSTI.GOV)

Allen, R.P.; Hazelton, R.F.

1985-09-01

As a followup to an FY-1984 cost/benefit study, a program was conducted in FY-1985 to transfer to the relevant DOE sites the information and technology for the direct conversion of transuranic (TRU) waste to low-level waste (LLW) by decontamination. As part of this work, the economic evaluation of the various TRUW volume reduction and conversion options was updated and expanded to include site-specific factors. The results show, for the assumptions used, that size reduction, size reduction followed by decontamination, or in situ decontamination are cost effective compared with the no-processing option. The technology transfer activities included site presentations and discussionsmore » with operations and waste management personnel to identify application opportunities and site-specific considerations and constraints that could affect the implementation of TRU waste conversion principles. These discussions disclosed definite potential for the beneficial application of these principles at most of the sites, but also confirmed the existence of site-specific factors ranging from space limitations to LLW disposal restrictions that could preclude particular applications or diminish expected benefits. 8 refs., 2 figs., 4 tabs.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rowe, M.D.; Pierce, B.L.

This report presents results of tests of different final site selection methods used for siting large-scale facilities such as nuclear power plants. Test data are adapted from a nuclear power plant siting study conducted on Long Island, New York. The purpose of the tests is to determine whether or not different final site selection methods produce different results, and to obtain some understanding of the nature of any differences found. Decision rules and weighting methods are included. Decision rules tested are Weighting Summation, Power Law, Decision Analysis, Goal Programming, and Goal Attainment; weighting methods tested are Categorization, Ranking, Rating Ratiomore » Estimation, Metfessel Allocation, Indifferent Tradeoff, Decision Analysis lottery, and Global Evaluation. Results show that different methods can, indeed, produce different results, but that the probability that they will do so is controlled by the structure of differences among the sites being evaluated. Differences in weights and suitability scores attributable to methods have reduced significance if the alternatives include one or two sites that are superior to all others in many attributes. The more tradeoffs there are among good and bad levels of different attributes at different sites, the more important are the specifics of methods to the final decision. 5 refs., 14 figs., 19 tabs.« less

77 FR 74457 - Foreign-Trade Zone 75-Phoenix, Arizona Application for Expansion (New Magnet Site) Under...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-14

..., Arizona Application for Expansion (New Magnet Site) Under Alternative Site Framework An application has...) adopted by the Board (15 CFR 400.2(c)) to include a new magnet site in Phoenix, Arizona. The application... zone project includes the following magnet sites: Site 1 (338 acres)--within the 550-acre Phoenix Sky...

Videoconferencing for site initiations in clinical studies: Mixed methods evaluation of usability, acceptability, and impact on recruitment.

PubMed

Randell, Rebecca; Backhouse, Michael R; Nelson, E Andrea

2016-12-01

A critical issue for multicentre clinical studies is conducting site initiations, ensuring sites are trained in study procedures and comply with relevant governance requirements before they begin recruiting patients. How technology can support site initiations has not previously been explored. This study sought to evaluate use of off-the-shelf web-based videoconferencing to deliver site initiations for a large national multicentre study. Participants in the initiations, including podiatrists, diabetologists, trial coordinators, and research nurses, completed an online questionnaire based on the System Usability Scale (SUS) (N = 15). This was followed by semi-structured interviews, with a consultant diabetologist, a trial coordinator, and three research nurses, exploring perceived benefits and limitations of videoconferencing. The mean SUS score for the videoconferencing platform was 87.2 (SD = 13.7), suggesting a good level of usability. Interview participants perceived initiations delivered by videoconferencing as being more interactive and easier to follow than those delivered by teleconference. In comparison to face-to-face initiations, videoconferencing takes less time, easily fitting in with the work of staff at the local sites. Perceptions of impact on communication varied according to the hardware used. Off-the-shelf videoconferencing is a viable alternative to face-to-face site initiations and confers advantages over teleconferencing.

Analysis of laparoscopic port site complications: A descriptive study

PubMed Central

Karthik, Somu; Augustine, Alfred Joseph; Shibumon, Mundunadackal Madhavan; Pai, Manohar Varadaraya

2013-01-01

CONTEXT: The rate of port site complications following conventional laparoscopic surgery is about 21 per 100,000 cases. It has shown a proportional rise with increase in the size of the port site incision and trocar. Although rare, complications that occur at the port site include infection, bleeding, and port site hernia. AIMS: To determine the morbidity associated with ports at the site of their insertion in laparoscopic surgery and to identify risk factors for complications. SETTINGS AND DESIGN: Prospective descriptive study. MATERIALS AND METHODS: In the present descriptive study, a total of 570 patients who underwent laparoscopic surgeries for various ailments between August 2009 and July 2011 at our institute were observed for port site complications prospectively and the complications were reviewed. STATISTICAL ANALYSIS USED: Descriptive statistical analysis was carried out in the present study. The statistical software, namely, SPSS 15.0 was used for the analysis of the data. RESULTS: Of the 570 patients undergoing laparoscopic surgery, 17 (3%) had developed complications specifically related to the port site during a minimum follow-up of three months; port site infection (PSI) was the most frequent (n = 10, 1.8%), followed by port site bleeding (n = 4, 0.7%), omentum-related complications (n = 2; 0.35%), and port site metastasis (n = 1, 0.175%). CONCLUSIONS: Laparoscopic surgeries are associated with minimal port site complications. Complications are related to the increased number of ports. Umbilical port involvement is the commonest. Most complications are manageable with minimal morbidity, and can be further minimized with meticulous surgical technique during entry and exit. PMID:23741110

Nuclear facility decommissioning and site remedial actions: a selected bibliography

DOE Office of Scientific and Technical Information (OSTI.GOV)

Owen, P.T.; Knox, N.P.; Fielden, J.M.

This bibliography contains 693 references with abstracts on the subject of nuclear facility decommissioning, uranium mill tailings management, and site remedial actions. Foreign, as well as domestic, literature of all types - technical reports, progress reports, journal articles, conference papers, symposium proceedings, theses, books, patents, legislation, and research project descriptions - has been included in this publication. The bibliography contains scientific (basic research as well as applied technology), economic, regulatory, and legal literature pertinent to the US Department of Energy's Remedial Action Program. Major chapters are Surplus Facilities Management Program, Nuclear Facilities Decommissioning, Formerly Utilized Sites Remedial Action Program, Uraniummore » Mill Tailings Remedial Action Program, Grand Junction Remedial Action Program, and Uranium Mill Tailings Management. Chapter sections for chapters 1 and 2 include: Design, Planning, and Regulations; Site Surveys; Decontamination Studies; Dismantlement and Demolition; Land Decontamination and Reclamation; Waste Disposal; and General Studies. The references within each chapter are arranged alphabetically by leading author. References having no individual author are arranged by corporate author or by title. Indexes are provided for (1) author; (2) corporate affiliation; (3) title; (4) publication description; (5) geographic location; and (6) keywords. An appendix of 202 bibliographic references without abstracts or indexes has been included in this bibliography. This appendix represents literature identified but not abstracted due to time constraints.« less

Initiatives to Develop Web Sites Including Information about Brownfields Properties

EPA Pesticide Factsheets

This web site was created to assist in planning, designing, and operating web sites that include information about individual brownfields properties. The report is of value to parties designing or managing such sites.

Dredging and contaminant exposure to tree swallows nesting on the upper Mississippi River

USGS Publications Warehouse

Custer, Thomas W.; Dummer, Paul; Custer, Christine M.; Warburton, David

2013-01-01

n 2008 and 2009, dredge material from the Mississippi River in Pool 8 south of Brownsville, Minnesota was used to construct nearby islands. Chemical analysis of sediment in 2001 and 2002 in the area to be dredged indicated detectable concentrations of organic and inorganic contaminants. Tree swallows (Tachycineta bicolor), whose diet is mainly aquatic invertebrates, were used to evaluate contaminant exposure in both the dredged and newly created habitat. Organic and inorganic contaminant data were collected from tree swallows in 2007 through 2010 at one study site near the dredging operation, a reference study site upriver from the dredging activity, one study site down river from the dredging activity, and one study site on a newly created island (2009 and 2010 only). Organic and element concentrations were at background levels in all samples. Polychlorinated biphenyl and p,p′-dichlorodiphenyldichloroethylene concentrations in tree swallow nestlings decreased at all study sites over the period 2007 to 2010 including the island study site between 2009 and 2010. Element concentrations in tree swallow livers for the non-island study sites did not show a trend among years in relation to the dredging. Selenium concentrations at the newly created island were higher and cadmium concentrations were lower in 2010 than 2009. Hatching success of eggs in successful nests was not associated with dredging activities.

Risk factors for acute surgical site infections after lumbar surgery: a retrospective study.

PubMed

Lai, Qi; Song, Quanwei; Guo, Runsheng; Bi, Haidi; Liu, Xuqiang; Yu, Xiaolong; Zhu, Jianghao; Dai, Min; Zhang, Bin

2017-07-19

Currently, many scholars are concerned about the treatment of postoperative infection; however, few have completed multivariate analyses to determine factors that contribute to the risk of infection. Therefore, we conducted a multivariate analysis of a retrospectively collected database to analyze the risk factors for acute surgical site infection following lumbar surgery, including fracture fixation, lumbar fusion, and minimally invasive lumbar surgery. We retrospectively reviewed data from patients who underwent lumbar surgery between 2014 and 2016, including lumbar fusion, internal fracture fixation, and minimally invasive surgery in our hospital's spinal surgery unit. Patient demographics, procedures, and wound infection rates were analyzed using descriptive statistics, and risk factors were analyzed using logistic regression analyses. Twenty-six patients (2.81%) experienced acute surgical site infection following lumbar surgery in our study. The patients' mean body mass index, smoking history, operative time, blood loss, draining time, and drainage volume in the acute surgical site infection group were significantly different from those in the non-acute surgical site infection group (p < 0.05). Additionally, diabetes mellitus, chronic obstructive pulmonary disease, osteoporosis, preoperative antibiotics, type of disease, and operative type in the acute surgical site infection group were significantly different than those in the non-acute surgical site infection group (p < 0.05). Using binary logistic regression analyses, body mass index, smoking, diabetes mellitus, osteoporosis, preoperative antibiotics, fracture, operative type, operative time, blood loss, and drainage time were independent predictors of acute surgical site infection following lumbar surgery. In order to reduce the risk of infection following lumbar surgery, patients should be evaluated for the risk factors noted above.

Off-site training of laparoscopic skills, a scoping review using a thematic analysis.

PubMed

Thinggaard, Ebbe; Kleif, Jakob; Bjerrum, Flemming; Strandbygaard, Jeanett; Gögenur, Ismail; Matthew Ritter, E; Konge, Lars

2016-11-01

The focus of research in simulation-based laparoscopic training has changed from examining whether simulation training works to examining how best to implement it. In laparoscopic skills training, portable and affordable box trainers allow for off-site training. Training outside simulation centers and hospitals can increase access to training, but also poses new challenges to implementation. This review aims to guide implementation of off-site training of laparoscopic skills by critically reviewing the existing literature. An iterative systematic search was carried out in MEDLINE, EMBASE, ERIC, Scopus, and PsychINFO, following a scoping review methodology. The included literature was analyzed iteratively using a thematic analysis approach. The study was reported in accordance with the STructured apprOach to the Reporting In healthcare education of Evidence Synthesis statement. From the search, 22 records were identified and included for analysis. A thematic analysis revealed the themes: access to training, protected training time, distribution of training, goal setting and testing, task design, and unsupervised training. The identified themes were based on learning theories including proficiency-based learning, deliberate practice, and self-regulated learning. Methods of instructional design vary widely in off-site training of laparoscopic skills. Implementation can be facilitated by organizing courses and training curricula following sound education theories such as proficiency-based learning and deliberate practice. Directed self-regulated learning has the potential to improve off-site laparoscopic skills training; however, further studies are needed to demonstrate the effect of this type of instructional design.

Daily survival rate and habitat characteristics of nests of Wilson's Plover

USGS Publications Warehouse

Zinsser, Elizabeth; Sanders, Felicia J.; Gerard, Patrick D.; Jodice, Patrick G.R.

2017-01-01

We assessed habitat characteristics and measured daily survival rate of 72 nests of Charadrius wilsonia (Wilson's Plover) during 2012 and 2013 on South Island and Sand Island on the central coast of South Carolina. At both study areas, nest sites were located at slightly higher elevations (i.e., small platforms of sand) relative to randomly selected nearby unused sites, and nests at each study area also appeared to be situated to enhance crypsis and/or vigilance. Daily survival rate (DSR) of nests ranged from 0.969 to 0.988 among study sites and years, and the probability of nest survival ranged from 0.405 to 0.764. Flooding and predation were the most common causes of nest failure at both sites. At South Island, DSR was most strongly related to maximum tide height, which suggests that flooding and overwash may be common causes of nest loss for Wilson's Plovers at these study sites. The difference in model results between the 2 nearby study sites may be partially due to more-frequent flooding at Sand Island because of some underlying yet unmeasured physiographic feature. Remaining data gaps for the species include regional assessments of nest and chick survival and habitat requirements during chick rearing.

BOREAS TGB-5 Dissolved Organic Carbon Data from NSA Beaver Ponds

NASA Technical Reports Server (NTRS)

Bourbonniere, Rick; Hall, Forrest G. (Editor); Conrad, Sara K. (Editor)

2000-01-01

The BOReal Ecosystem-Atmosphere Study Trace Gas Biogeochemistry (BOREAS TGB-5) team collected several data sets related to carbon and trace gas fluxes and concentrations in the Northern Study Area (NSA). This data set contains concentrations of dissolved organic and inorganic carbon species from water samples collected at various NSA sites. In particular, this set covers the NSA Tower Beaver Pond Site and the NSA Gillam Road Beaver Pond Site, including data from all visits to open water sampling locations during the BOREAS field campaigns from April to September 1994. The data are provided in tabular ASCII files.

Eco-restoration of a high-sulphur coal mine overburden dumping site in northeast India: A case study

NASA Astrophysics Data System (ADS)

Dowarah, J.; Deka Boruah, H. P.; Gogoi, J.; Pathak, N.; Saikia, N.; Handique, A. K.

2009-10-01

Eco-restoration of mine overburden (OB) or abandoned mine sites is a major environmental concern. In the present investigation, an integrated approach was used to rejuvenate a high-sulphur mine OB dumping site in the Tirap Collieries, Assam, India, which is situated in the Indo-Burma mega-biodiversity hotspot. A mine OB is devoid of true soil character with poor macro and micronutrient content and contains elevated concentrations of trace and heavy metals. Planting of herbs, shrubs, cover crops and tree species at close proximity leads to primary and secondary sere state succession within a period of 3 to 5 years. A variety of plant species were screened for potential use in restoration: herbs, including Sccharum spontaneum, Cymbopogon winterianus Jowitt (citronella), and Cymbopogon flexuosus (lemon grass) cover plants, including Mimosa strigillosa, M. striata, and M. pigra; shrubs, including Sesbania rostrata (dhaincha) and Cassia streata (cassia); and tree species, including Gmelina arborea (gomari) and Dalbergia sissoo (sissoo). Amendment with unmined soil and bio-organic matter was required for primary establishment of some plant species. Management of these plant species at the site will ensure long term sustainable eco-restoration of the coal mine-degraded land.

Problematic use of social networking sites among urban school going teenagers.

PubMed

Meena, Parth Singh; Mittal, Pankaj Kumar; Solanki, Ram Kumar

2012-07-01

Social networking sites like Facebook, Orkut and Twitter are virtual communities where users can create individual public profiles, interact with real-life friends and meet other people based on shared interests. An exponential rise in usage of Social Networking Sites have been seen within the last few years. Their ease of use and immediate gratification effect on users has changed the way people in general and students in particular spend their time. Young adults, particularly teenagers tended to be unaware of just how much time they really spent on social networking sites. Negative correlates of Social Networking Sites usage include the decrease in real life social community participation and academic achievement, as well as relationship problems, each of which may be indicative of potential addiction. the aim of the study was to find out whether teenagers, specially those living in cities spend too much time on social networking websites. 200 subjects, both boys and girls were included in the cross sectional study who were given a 20 item Young's internet addiction test modified for social networking sites. The responses were analyzed using chi square test and Fisher's exact test. 24.74% of the students were having occasional or 'frequency' problems while 2.02% of them were experiencing severe problems due to excessive time spent using social networking sites. With the ever increasing popularity of social media, teenagers are devoting significant time to social networking on websites and are prone to get 'addicted' to such form of online social interaction.

AFB/open cycle gas turbine conceptual design study

NASA Technical Reports Server (NTRS)

Dickinson, T. W.; Tashjian, R.

1983-01-01

Applications of coal fired atmospheric fluidized bed gas turbine systems in industrial cogeneration are identified. Based on site-specific conceptual designs, the potential benefits of the AFB/gas turbine system were compared with an atmospheric fluidized design steam boiler/steam turbine system. The application of these cogeneration systems at four industrial plant sites is reviewed. A performance and benefit analysis was made along with a study of the representativeness of the sites both in regard to their own industry and compared to industry as a whole. A site was selected for the conceptual design, which included detailed site definition, AFB/gas turbine and AFB/steam turbine cogeneration system designs, detailed cost estimates, and comparative performance and benefit analysis. Market and benefit analyses identified the potential market penetration for the cogeneration technologies and quantified the potential benefits.

AFB/open cycle gas turbine conceptual design study

NASA Astrophysics Data System (ADS)

Dickinson, T. W.; Tashjian, R.

1983-09-01

Applications of coal fired atmospheric fluidized bed gas turbine systems in industrial cogeneration are identified. Based on site-specific conceptual designs, the potential benefits of the AFB/gas turbine system were compared with an atmospheric fluidized design steam boiler/steam turbine system. The application of these cogeneration systems at four industrial plant sites is reviewed. A performance and benefit analysis was made along with a study of the representativeness of the sites both in regard to their own industry and compared to industry as a whole. A site was selected for the conceptual design, which included detailed site definition, AFB/gas turbine and AFB/steam turbine cogeneration system designs, detailed cost estimates, and comparative performance and benefit analysis. Market and benefit analyses identified the potential market penetration for the cogeneration technologies and quantified the potential benefits.

A study of possible ground-motion amplification at the Coyote Lake Dam, California

USGS Publications Warehouse

Boore, D.M.; Graizer, V.M.; Tinsley, J.C.; Shakal, A.F.

2004-01-01

The abutment site at the Coyote Lake Dam recorded an unusually large peak acceleration of 1.29g during the 1984 Morgan Hill earthquake. Following this earthquake another strong-motion station was installed about 700 m downstream from the abutment station. We study all events (seven) recorded on these stations, using ratios of peak accelerations, spectral ratios, and particle motion polarization (using holograms) to investigate the relative ground motion at the two sites. We find that in all but one case the motion at the abutment site is larger than the downstream site over a broad frequency band. The polarizations are similar for the two sites for a given event, but can vary from one event to another. This suggests that the dam itself is not strongly influencing the records. Although we can be sure that the relative motion is usually larger at the abutment site, we cannot conclude that there is anomalous site amplification at the abutment site. The downstream site could have lower-than-usual near-surface amplifications. On the other hand, the geology near the abutment site is extremely complex and includes fault slivers, with rapid lateral changes in materials and presumably seismic velocities. For this reason alone, the abutment site should not be considered a normal free-field site.

75 FR 26793 - Beam Global Spirits & Wine, Including On-Site Leased Workers from Adecco, St. Elizabeth Business...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-12

... & Wine, Including On-Site Leased Workers from Adecco, St. Elizabeth Business Health, Guardsmark, and Lab... 26, 2010, applicable to workers of Beam Global Spirits & Wine, including on-site leased workers from... on-site at the Cincinnati, Ohio location of Beam Global Spirits & Wine. The Department has determined...

Apollo 17 preliminary science report. [Apollo 17 investigation of Taurus-Littrow lunar region

NASA Technical Reports Server (NTRS)

1973-01-01

An analysis of the Apollo 17 flight is presented in the form of a preliminary science report. The subjects discussed are: (1) Apollo 17 site selection, (2) mission description, (3) geological investigation of landing site, (4) lunar experiments, (5) visual flight flash phenomenon, (6) volcanic studies, (7) mare ridges and related studies, (8) remote sensing and photogrammetric studies, and (9) astronomical photography. Extensive photographic data are included for all phases of the mission.

Lessons from Initiating the First Veterans Health Administration (VA) Women's Health Practice-based Research Network (WH-PBRN) Study.

PubMed

Pomernacki, Alyssa; Carney, Diane V; Kimerling, Rachel; Nazarian, Deborah; Blakeney, Jill; Martin, Brittany D; Strehlow, Holly; Yosef, Julia; Goldstein, Karen M; Sadler, Anne G; Bean-Mayberry, Bevanne A; Bastian, Lori A; Bucossi, Meggan M; McLean, Caitlin; Sonnicksen, Shannan; Klap, Ruth; Yano, Elizabeth M; Frayne, Susan M

2015-01-01

The Veterans Health Administration (VA) Women's Health Practice-Based Research Network (WH-PBRN) was created to foster innovations for the health care of women veterans. The inaugural study by the WH-PBRN was designed to identify women veterans' own priorities and preferences for mental health services and to inform refinements to WH-PBRN operational procedures. Addressing the latter, this article reports lessons learned from the inaugural study. WH-PBRN site coordinators at the 4 participating sites convened weekly with the study coordinator and the WH-PBRN program manager to address logistical issues and identify lessons learned. Findings were categorized into a matrix of challenges and facilitators related to key study elements. Challenges to the conduct of PBRN-based research included tracking of regulatory documents; cross-site variability in some regulatory processes; and troubleshooting logistics of clinic-based recruitment. Facilitators included a central institutional review board, strong relationships between WH-PBRN research teams and women's health clinic teams, and the perception that women want to help other women veterans. Our experience with the inaugural WH-PBRN study demonstrated the feasibility of establishing productive relationships between local clinicians and researchers, and of recruiting a special population (women veterans) in diverse sites within an integrated health care system. This identified strengths of a PBRN approach. © Copyright 2015 by the American Board of Family Medicine.

Assessing the challenges of multi-scope clinical research sites: an example from NIH HIV/AIDS clinical trials networks.

PubMed

Rosas, Scott R; Cope, Marie T; Villa, Christie; Motevalli, Mahnaz; Utech, Jill; Schouten, Jeffrey T

2014-04-01

Large-scale, multi-network clinical trials are seen as a means for efficient and effective utilization of resources with greater responsiveness to new discoveries. Formal structures instituted within the National Institutes of Health (NIH) HIV/AIDS Clinical Trials facilitate collaboration and coordination across networks and emphasize an integrated approach to HIV/AIDS vaccine, prevention and therapeutics clinical trials. This study examines the joint usage of clinical research sites as means of gaining efficiency, extending capacity, and adding scientific value to the networks. A semi-structured questionnaire covering eight clinical management domains was administered to 74 (62% of sites) clinical site coordinators at single- and multi-network sites to identify challenges and efficiencies related to clinical trials management activities and coordination with multi-network units. Overall, respondents at multi-network sites did not report more challenges than single-network sites, but did report unique challenges to overcome including in the areas of study prioritization, community engagement, staff education and training, and policies and procedures. The majority of multi-network sites reported that such affiliations do allow for the consolidation and cost-sharing of research functions. Suggestions for increasing the efficiency or performance of multi-network sites included streamlining standards and requirements, consolidating protocol activation methods, using a single cross-network coordinating centre, and creating common budget and payment mechanisms. The results of this assessment provide important information to consider in the design and management of multi-network configurations for the NIH HIV/AIDS Clinical Trials Networks, as well as others contemplating and promoting the concept of multi-network settings. © 2013 John Wiley & Sons Ltd.

Is wetland mitigation successful in Southern California?

NASA Astrophysics Data System (ADS)

Cummings, D. L.; Rademacher, L. K.

2004-12-01

Wetlands perform many vital functions within their landscape position; they provide unique habitats for a variety of flora and fauna and they act as treatment systems for upstream natural and anthropogenic waste. California has lost an estimated 91% of its wetlands. Despite the 1989 "No Net Loss" policy and mitigation requirements by the regulatory agencies, the implemented mitigation may not be offsetting wetlands losses. The "No Net Loss" policy is likely failing for numerous reasons related to processes in the wetlands themselves and the policies governing their recovery. Of particular interest is whether these mitigation sites are performing essential wetlands functions. Specific questions include: 1) Are hydric soil conditions forming in mitigation sites; and, 2) are the water quality-related chemical transformations that occur in natural wetlands observed in mitigation sites. This study focuses on success (or lack of success) in wetlands mitigation sites in Southern California. Soil and water quality investigations were conducted in wetland mitigation sites deemed to be successful by vegetation standards. Observations of the Standard National Resource Conservation Service field indicators of reducing conditions were made to determine whether hydric soil conditions have developed in the five or more years since the implementation of mitigation plans. In addition, water quality measurements were performed at the inlet and outlet of these mitigation sites to determine whether these sites perform similar water quality transformations to natural wetlands within the same ecosystem. Water quality measurements included nutrient, trace metal, and carbon species measurements. A wetland location with minimal anthropogenic changes and similar hydrologic and vegetative features was used as a control site. All sites selected for study are within a similar ecosystem, in the interior San Diego and western Riverside Counties, in Southern California.

Effect of membrane exposure on guided bone regeneration: A systematic review and meta-analysis.

PubMed

Garcia, Jeffrey; Dodge, Austin; Luepke, Paul; Wang, Hom-Lay; Kapila, Yvonne; Lin, Guo-Hao

2018-03-01

This review aimed at investigating the effect of membrane exposure on guided bone regeneration (GBR) outcomes at peri-implant sites and edentulous ridges. Electronic and manual literature searches were conducted by two independent reviewers using four databases, including MEDLINE, EMBASE, Web of Science, and Cochrane Central Register of Controlled Trials, for articles up to February 2017. Articles were included if they were human clinical trials or case series reporting outcomes of GBR procedures with and without membrane exposure. A random-effects meta-analysis was conducted, and the weighted mean difference (WMD) between the two groups and 95% confidence interval (CI) were reported. Overall, eight articles were included in the quantitative analysis. The WMD of the horizontal bone gain at edentulous ridges was -76.24% (95% CI = -137.52% to -14.97%, p = .01) between sites with membrane exposure and without exposure. In addition, the WMD of the dehiscence reduction at peri-implant sites was -27.27% (95% CI of -45.87% to -8.68%, p = .004). Both analyses showed significantly favorable outcomes at the sites without membrane exposure. Based on the findings of this study, membrane exposure after GBR procedures has a significant detrimental influence on the outcome of bone augmentation. For the edentulous ridges, the sites without membrane exposure achieved 74% more horizontal bone gain than the sites with exposure. For peri-implant dehiscence defects, the sites without membrane exposure had 27% more defect reduction than the sites with exposure. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Structure, Process, and Culture Differences of Pediatric Trauma Centers Participating in an International Comparative Effectiveness Study of Children with Severe Traumatic Brain Injury.

PubMed

Larsen, Gitte Y; Schober, Michelle; Fabio, Anthony; Wisniewski, Stephen R; Grant, Mary Jo C; Shafi, Nadeem; Bennett, Tellen D; Hirtz, Deborah; Bell, Michael J

2016-06-01

Traumatic brain injury (TBI) is an important worldwide cause of death and disability for children. The Approaches and Decisions for Acute Pediatric TBI (ADAPT) Trial is an observational, cohort study to compare the effectiveness of six aspects of TBI care. Understanding the differences between clinical sites-including their structure, clinical processes, and culture differences-will be necessary to assess differences in outcome from the study and can inform the overall community regarding differences across academic centers. We developed a survey and queried ADAPT site principal investigators with a focus on six domains: (i) hospital, (ii) pediatric intensive care unit (PICU), (iii) medical staff characteristics, (iv) quality of care, (v) medication safety, and (vi) safety culture. Summary statistics were used to describe differences between centers. ADAPT clinical sites that enrolled a subject within the first year (32 US-based, 11 international) were studied. A wide variation in site characteristics was observed in hospital and ICU characteristics, including an almost sevenfold range in ICU size (8-55 beds) and more than fivefold range of overall ICU admissions (537-2623). Nursing staffing (predominantly 1:1 or 1:2) and the presence of pharmacists within the ICU (79 %) were less variable, and most sites "strongly agreed" or "agreed" that Neurosurgery and Critical Care teams worked well together (81.4 %). However, a minority of sites (46 %) used an explicit protocol for treatment of children with severe TBI care. We found a variety of inter-center structure, process, and culture differences. These intrinsic differences between sites may begin to explain why interventional studies have failed to prove efficacy of experimental therapies. Understanding these differences may be an important factor in analyzing future ADAPT trial results and in determining best practices for pediatric severe TBI.

Ab initio molecular orbital studies of the positive muon and muonium in 4-arylmethyleneamino-TEMPO derivatives

NASA Astrophysics Data System (ADS)

Briere, T. M.; Jeong, J.; Das, T. P.; Ohira, S.; Nagamine, K.

2000-08-01

The muon and muonium bonding sites of the 4-arylmethyleneamino-2,2,6,6-tetramethylpiperidin-1-yloxyl radical crystals with aryl groups consisting of biphenyl and 4-pyridyl were studied via ab initio Hartree-Fock theory. The hyperfine fields, including both intramolecular and intermolecular interactions, were calculated at the sites of interest and compared to zero field μSR results.

ALS Multicenter Cohort Study of Oxidative Stress (ALS COSMOS): study methodology, recruitment, and baseline demographic and disease characteristics.

PubMed

Mitsumoto, Hiroshi; Factor-Litvak, Pam; Andrews, Howard; Goetz, Raymond R; Andrews, Leslie; Rabkin, Judith G; McElhiney, Martin; Nieves, Jeri; Santella, Regina M; Murphy, Jennifer; Hupf, Jonathan; Singleton, Jess; Merle, David; Kilty, Mary; Heitzman, Daragh; Bedlack, Richard S; Miller, Robert G; Katz, Jonathan S; Forshew, Dallas; Barohn, Richard J; Sorenson, Eric J; Oskarsson, Bjorn; Fernandes Filho, J Americo M; Kasarskis, Edward J; Lomen-Hoerth, Catherine; Mozaffar, Tahseen; Rollins, Yvonne D; Nations, Sharon P; Swenson, Andrea J; Shefner, Jeremy M; Andrews, Jinsy A; Koczon-Jaremko, Boguslawa A

2014-06-01

Abstract In a multicenter study of newly diagnosed ALS patients without a reported family history of ALS, we are prospectively investigating whether markers of oxidative stress (OS) are associated with disease progression. Methods utilize an extensive structured telephone interview ascertaining environmental, lifestyle, dietary and psychological risk factors associated with OS. Detailed assessments were performed at baseline and at 3-6 month intervals during the ensuing 30 months. Our biorepository includes DNA, plasma, urine, and skin. Three hundred and fifty-five patients were recruited. Subjects were enrolled over a 36-month period at 16 sites. To meet the target number of subjects, the recruitment period was prolonged and additional sites were included. Results showed that demographic and disease characteristics were similar between 477 eligible/non-enrolled and enrolled patients, the only difference being type of health insurance among enrolled patients. Sites were divided into three groups by the number of enrolled subjects. Comparing these three groups, the Columbia site had fewer 'definite ALS' diagnoses. This is the first prospective, interdisciplinary, in-depth, multicenter epidemiological investigation of OS related to ALS progression and has been accomplished by an aggressive recruitment process. The baseline demographic and disease features of the study sample are now fully characterized.

Water-quality data for the Clark Fork and selected tributaries from Deer Lodge to Milltown, Montana, March 1985 through June 1986

USGS Publications Warehouse

Lambing, J.H.

1987-01-01

A sampling program was conducted at six stream sites. The purpose of the study was to collect baseline data on concentrations of suspended sediment and selected trace metals in streamflow. Included in this report are tables of daily data for mean streamflow, suspended sediment concentration, and suspended sediment discharge at two streamflow gaging stations on the Clark Fork; periodic data for instantaneous streamflow, onsite water quality, and trace metal and suspended sediment concentrations in the Clark Fork and tributaries; and summary statistics for all the water quality data. Also included are graphs for each site showing median concentrations of trace metals, relationship of concentrations of trace metals to suspended sediment, and median concentrations of trace metals in suspended sediments. Hydrographs for two sites on the main stem show daily mean streamflow, suspended sediment concentration, and suspended sediment discharge for the period of study. (Author 's abstract)

Installation-restoration program. Phase 2. Confirmation/quantification. Stage 1 for Mather AFB, Sacramento, California. Volume 1. Final report, September 1983-June 1986

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

A Problem Confirmation Study was performed at three sites on Mather AFB identified in the Phase I investigation as requiring further study (the Air command and warning Area, the 7100 Area, the West Ditch) and the Northeast Perimeter. The field investigation was conducted from February 1984 to June 1985 and included installation of 11 monitor wells, collection of groundwater samples from the monitor wells and 15 base production wells, and collection of sediment samples from two locations on the West Ditch. Analytes included oil and grease, TOC, volatile organic compounds (VOA), as well as dimethylnitrosamine, phenols, pesticides, and dissolved metalsmore » at some specific sites. Based on the hydrogeologic complexity of the physical setting and the findings of the sampling and analytical work, follow-on investigations were recommended at all three sites.« less

EPConDB: a web resource for gene expression related to pancreatic development, beta-cell function and diabetes.

PubMed

Mazzarelli, Joan M; Brestelli, John; Gorski, Regina K; Liu, Junmin; Manduchi, Elisabetta; Pinney, Deborah F; Schug, Jonathan; White, Peter; Kaestner, Klaus H; Stoeckert, Christian J

2007-01-01

EPConDB (http://www.cbil.upenn.edu/EPConDB) is a public web site that supports research in diabetes, pancreatic development and beta-cell function by providing information about genes expressed in cells of the pancreas. EPConDB displays expression profiles for individual genes and information about transcripts, promoter elements and transcription factor binding sites. Gene expression results are obtained from studies examining tissue expression, pancreatic development and growth, differentiation of insulin-producing cells, islet or beta-cell injury, and genetic models of impaired beta-cell function. The expression datasets are derived using different microarray platforms, including the BCBC PancChips and Affymetrix gene expression arrays. Other datasets include semi-quantitative RT-PCR and MPSS expression studies. For selected microarray studies, lists of differentially expressed genes, derived from PaGE analysis, are displayed on the site. EPConDB provides database queries and tools to examine the relationship between a gene, its transcriptional regulation, protein function and expression in pancreatic tissues.

Physical, chemical, and biological data for detailed study of irrigation drainage in the San Juan River area, New Mexico, 1993-94, with supplemental data, 1991-95

USGS Publications Warehouse

Thomas, C.L.; Lusk, J.D.; Bristol, R.S.; Wilson, R.M.; Shineman, A.R.

1997-01-01

In response to increasing concern about the quality of irrigation drainage and its potential effects on fish, wildlife, and human health, the U.S. Department of the Interior formed an interbureau task group to prepare a plan for investigating water- quality problems on irrigation projects sponsored by the Department of the Interior. The San Juan River area in northwestern New Mexico was one of the areas designated for study. Investigators collected water, bottom-sediment, soil, and biological samples at more than 50 sites in the San Juan River area during 1993-94. Sample sites included (1) sites located within Department of the Interior irrigation project service areas, or areas that receive drainage from irrigation projects; (2) reference sites for comparison with irrigation project sites; and (3) sites located within the reach of the San Juan River from Navajo Dam to 10 miles downstream from the dam. The types of habitat sampled included the main stem of the San Juan River, backwater areas adjacent to the San Juan River, tributaries to the San Juan River, ponds, seeps, irrigation-delivery canals, irrigation-drainage canals, a stock tank, and shallow ground water. The types of media sampled included water, bottom sediment, soil, aquatic plants, aquatic invertebrates, amphibians, and fish. Semipermeable-membrane devices were used as a surrogate medium to sample both air and water in some instances. Sample measurements included concentrations of major ions, trace elements, organochlorine pesticides, polychlorinated biphenyls, polycyclic-aromatic-hydrocarbon compounds, and stable isotopes of hydrogen and oxygen. This report presents tables of physical, chemical, and biological data collected for the U.S. Department of the Interior National Irrigation Water-Quality Program. Additionally, supplemental physical, chemical, and biological data collected in association with the Navajo Indian Irrigation Project are presented.

Exposure chain of urban air PM 2.5—associations between ambient fixed site, residential outdoor, indoor, workplace and personal exposures in four European cities in the EXPOLIS-study

NASA Astrophysics Data System (ADS)

Kousa, Anu; Oglesby, Lucy; Koistinen, Kimmo; Künzli, Nino; Jantunen, Matti

In the EXPOLIS study personal exposures and microenvironment levels of air pollutants from 50-201 urban adult (25-55 yr) participants were measured in six European cities during 1 yr from autumn 1996 to winter 1997-98. This paper presents the associations between the personal PM 2.5 exposures, microenvironment (residential indoor, residential outdoor and workplace indoor) and ambient fixed site concentrations measured in Helsinki (Finland), Basel (Switzerland), Prague (Czech Republic) and Athens (Greece). Considering the whole chain from ambient fixed site to residential outdoor, residential indoor and personal leisure time (non-working hours) exposure, the correlations were highest between personal leisure time exposures and residential indoor concentrations (non-environmental tobacco smoke (ETS): Pearson r=0.72-0.92, ETS included: r=0.82-0.86) except in Athens, where the correlation between residential indoor and outdoor air was highest (non-ETS: r=0.82, ETS included: r=0.68)). Unfortunately, ambient fixed site PM 2.5 concentrations were measured continuously only in Helsinki. Ambient fixed site PM 2.5 concentrations correlated quite well with residential outdoor concentrations ( r=0.90), and also with residential indoor (non-ETS) concentrations ( r=0.80), but concentrations measured at ambient fixed site monitors were poor predictors of personal exposures to PM 2.5. They were particularly poor predictors of personal workday exposures (non-ETS: r=0.34, ETS included: r=0.25), but considerably better for personal leisure time exposures (non-ETS: r=0.69, ETS included: r=0.54). According to log-linear regression models combined from all centres of non-ETS-exposed participants, residential indoor concentrations explained 76% of personal leisure time PM 2.5 exposure variation and workplace indoor concentrations explained 66% of the workday exposure variation.

The association between shallow vestibular depth and peri-implant parameters: a retrospective 6 years longitudinal study.

PubMed

Halperin-Sternfeld, Michal; Zigdon-Giladi, Hadar; Machtei, Eli E

2016-03-01

The aim of this study was to retrospectively evaluate the association between shallow vestibular depth (VD) and peri-implant parameters. Peri-implant parameters were evaluated in 61 periodontal patients under regular supportive periodontal therapy. Clinical parameters included gingival index (GI), plaque index (PI), bleeding on probing (BOP), peri-implant pocket depths (PPD), mucosal recession (MR), relative attachment level (RAL), width and thickness of keratinized mucosa (KMW, KMT) and VD. Radiographic bone level (RBL) was measured on peri-apical radiographs. Sites with shallow VD (≤ 4 mm) were associated with higher MR (0.91 mm versus 0.47 mm, p ≤ 0.009), higher RAL (4.23 mm versus 3.59 mm, p ≤ 0.0001) and higher RBL (2.18 mm versus 1.7 mm, p = 0.05) when compared with adequate vestibular depth sites (VD > 4 mm). Moreover, sites with shallow VD presented lower KMW compared with sites with adequate VD (1.24 mm versus 2.38 mm, respectively, p ≤ 0.0001). Slightly greater BOP, and GI were recorded for the shallow VD compared with adequate sites. According to multivariate analysis, factors that could predict RAL included: VD, GI, age, supporting periodontal therapy, implant type and design. Based on this study, inadequate vestibular depth around dental implants may be associated with increased peri-implant bone loss and mucosal recession. Further prospective and intervention studies will be required to fully understand this phenomenon. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

77 FR 62535 - Hydro Aluminum North America, Inc., Midwest Region, Including On-Site Leased Workers From...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-15

... Aluminum North America, Inc., Midwest Region, Including On- Site Leased Workers From Employment Group, Aerotek, and Manpower, Kalamazoo, Michigan; Hydro Aluminum North America, Inc., Midwest Region, Including... Aluminum North America, Inc., Kalamazoo, Michigan. The subject worker group includes on-site leased workers...

78 FR 19530 - Eastman Kodak Company (GCG), Electrographic Print Solutions, Including On-Site Leased Workers...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-01

... Kodak Company (GCG), Electrographic Print Solutions, Including On-Site Leased Workers From Adecco and Datrose, Spencerport, New York; Eastman Kodak Company, IPS, Including On-Site Leased Workers From Adecco..., 2011, applicable to workers of Eastman Kodak Company (GCG), Electrographic Print Solutions, including...

76 FR 28453 - Cesar Chavez Special Resource Study-Alameda, Fresno, Imperial, Kern, Los Angeles, Monterey...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-17

... Environmental Policy Act of 1969 (Pub L. 91-190) and Council on Environmental Quality's implementing regulations... of California, and other states that are significant to the life of Cesar Chavez and the farm labor... sites posses nationally significant cultural resources; whether the sites include types or quality of...

Glacier Lakes Ecosystem Experiment Site: an "Experimental" wilderness

Treesearch

Douglas G. Fox; Anna W. Schoettle; Frank A. Vertucci

1987-01-01

This site, selected to be representative of high-mountain wilderness ecosystems, is being used to study the effects of air pollution and atmospheric deposition In alpine and subalpine, terrestrial and aquatic biotic communities. The research program includes (a) short-term experiments designed to quantify the response of system components hypothesized to be most...

Selection and Cataloging of Adult Pornography Web Sites for Academic Libraries

ERIC Educational Resources Information Center

Dilevko, Juris; Gottlieb, Lisa

2004-01-01

Pornography has become part of mainstream culture. As such, it has become a subject of academic research, and this, in turn, has implications for university libraries. Focusing on adult Internet pornography, this study suggests that academic libraries should provide access to adult pornographic Web sites by including them in their online catalogs.

Designing Multi-Channel Web Frameworks for Cultural Tourism Applications: The MUSE Case Study.

ERIC Educational Resources Information Center

Garzotto, Franca; Salmon, Tullio; Pigozzi, Massimiliano

A framework for the design of multi-channel (MC) applications in the cultural tourism domain is presented. Several heterogeneous interface devices are supported including location-sensitive mobile units, on-site stationary devices, and personalized CDs that extend the on-site experience beyond the visit time thanks to personal memories gathered…

Implementation of the century ecosystem model for an eroding hillslope in Mississippi

USGS Publications Warehouse

Sharpe, Jodie; Harden, Jennifer W.; Dabney, Seth M.; Ojima, Dennis; Parton, William

1998-01-01

The objective of this study was to parameterize and implement the Century ecosystem model for an eroding, cultivated site near Senatobia, in Panola County, Mississippi, in order to understand the loss and replacement of soil organic carbon on an eroding cropland. The sites chosen for this study are located on highly eroded loess soils where USDA has conducted studies on rates of soil erosion. We used USDA sediment data from the study site and historical erosion estimates from the nearby area as model input for soil loss; in addition, inputs for parametization include particle-size data, climate data, and rainfall/runoff data that were collected and reported in companion papers. A cropping scenario was implemented to simulate a research site at the USDA watershed 2 at the Nelson Farm. Model output was compiled for comparison with data collected and reported in companion reports; interpretive comparisons are reported in Harden et al, in press.

Using Formative Research to Develop Environmental and Ecological Interventions to Address Overweight and Obesity

PubMed Central

Wilson, Mark G.; Goetzel, Ron Z.; Ozminkowski, Ronald J.; DeJoy, Dave M.; Della, Lindsay; Roemer, Enid Chung; Schneider, Jennifer; Tully, Karen J.; White, John M.; Baase, Catherine M.

2010-01-01

Objective This paper presents the formative research phase of a large multi-site intervention study conducted to inform the feasibility of introducing environmental and ecological interventions. Methods Using mixed methods that included an environmental assessment, climate survey, leadership focus groups and interviews, and archival data, information was collected on employee health and job factors, the physical environment, social-organizational environment, and current health programs. Results Results show that 83% of employees at the study sites were overweight or obese. Leadership was very supportive of health initiatives and felt integrating the strategies into organizational operations would increase their likelihood of success. Environmental assessment scores ranged from 47 to 19 on a 100 point scale. Health services personnel tended to view the organizational climate for health more positively than site leadership (mean of 3.6 vs 3.0 respectively). Conclusions Intervention strategies chosen included increasing healthy food choices in vending, cafeterias, and company meetings, providing a walking path, targeting messages, developing site goals, training leaders, and establishing leaders at the work group level. PMID:18073340

Hereditary Angioedema Attacks: Local Swelling at Multiple Sites.

PubMed

Hofman, Zonne L M; Relan, Anurag; Hack, C Erik

2016-02-01

Hereditary angioedema (HAE) patients experience recurrent local swelling in various parts of the body including painful swelling of the intestine and life-threatening laryngeal oedema. Most HAE literature is about attacks located in one anatomical site, though it is mentioned that HAE attacks may also involve multiple anatomical sites simultaneously. A detailed description of such multi-location attacks is currently lacking. This study investigated the occurrence, severity and clinical course of HAE attacks with multiple anatomical locations. HAE patients included in a clinical database of recombinant human C1-inhibitor (rhC1INH) studies were evaluated. Visual analog scale scores filled out by the patients for various symptoms at various locations and investigator symptoms scores during the attack were analysed. Data of 219 eligible attacks in 119 patients was analysed. Thirty-three patients (28%) had symptoms at multiple locations in anatomically unrelated regions at the same time during their first attack. Up to five simultaneously affected locations were reported. The observation that severe HAE attacks often affect multiple sites in the body suggests that HAE symptoms result from a systemic rather than from a local process as is currently believed.

Revealing Atomic-Level Mechanisms of Protein Allostery with Molecular Dynamics Simulations.

PubMed

Hertig, Samuel; Latorraca, Naomi R; Dror, Ron O

2016-06-01

Molecular dynamics (MD) simulations have become a powerful and popular method for the study of protein allostery, the widespread phenomenon in which a stimulus at one site on a protein influences the properties of another site on the protein. By capturing the motions of a protein's constituent atoms, simulations can enable the discovery of allosteric binding sites and the determination of the mechanistic basis for allostery. These results can provide a foundation for applications including rational drug design and protein engineering. Here, we provide an introduction to the investigation of protein allostery using molecular dynamics simulation. We emphasize the importance of designing simulations that include appropriate perturbations to the molecular system, such as the addition or removal of ligands or the application of mechanical force. We also demonstrate how the bidirectional nature of allostery-the fact that the two sites involved influence one another in a symmetrical manner-can facilitate such investigations. Through a series of case studies, we illustrate how these concepts have been used to reveal the structural basis for allostery in several proteins and protein complexes of biological and pharmaceutical interest.

Reptile assemblage response to restoration of fire-suppressed longleaf pine sandhills.

PubMed

Steen, David A; Smith, Lora L; Conner, L M; Litt, Andrea R; Provencher, Louis; Hiers, J Kevin; Pokswinski, Scott; Guyer, Craig

2013-01-01

Measuring the effects of ecological restoration on wildlife assemblages requires study on broad temporal and spatial scales. Longleaf pine (Pinus palustris) forests are imperiled due to fire suppression and subsequent invasion by hardwood trees. We employed a landscape-scale, randomized-block design to identify how reptile assemblages initially responded to restoration treatments including removal of hardwood trees via mechanical methods (felling and girdling), application of herbicides, or prescribed burning alone. Then, we examined reptile assemblages after all sites experienced more than a decade of prescribed burning at two- to thee-year return intervals. Data were collected concurrently at reference sites chosen to represent target conditions for restoration. Reptile assemblages changed most rapidly in response to prescribed burning, but reptile assemblages at all sites, including reference sites, were generally indistinguishable by the end of the study. Thus, we suggest that prescribed burning in longleaf pine forests over long time periods is an effective strategy for restoring reptile assemblages to the reference condition. Application of herbicides or mechanical removal of hardwood trees provided no apparent benefit to reptiles beyond what was achieved by prescribed fire alone.

U.S. Geological Survey research in radioactive waste disposal - Fiscal years 1983, 1984, and 1985

USGS Publications Warehouse

Dinwiddie, G.A.; Trask, N.J.

1986-01-01

The report summarizes progress on geologic and hydrologic research related to the disposal of radioactive wastes. The research is described according to whether it is related most directly to: (1) high-level and transuranic wastes, (2) low-level wastes, or (3) uranium mill tailings. Included is research applicable to the identification and geohydrologic characterization of waste-disposal sites, to investigations of specific sites where wastes have been stored, and to studies of regions or environments where waste-disposal sites might be located. A significant part of the activity is concerned with techniques and methods for characterizing disposal sites and studies of geologic and hydrologic processes related to the transport and (or) retention of waste radionuclides.

Analysis of Internet information on the controversial X-Stop device.

PubMed

Anderson, Joshua T; Sullivan, T Barrett; Ahn, Uri M; Ahn, Nicholas U

2014-10-01

The Internet is frequently used by patients to aid in medical decision making. Multiple studies display the Internet's ineffectiveness in presenting high-quality information regarding surgical procedures and devices. With recent reports of unacceptably high complication rates and poor outcomes with the X-Stop device, it is important that online information is comprehensive and accurate. This study is the first to examine Internet information on the controversial X-Stop. To determine how accurately public information over the Internet portrays the existing primary literature on the X-Stop, how extensively the X-Stop is characterized online, and how patient decision making could foreseeably be affected. This cross-sectional study analyzed publicly available Internet information, including videos on the web site YouTube regarding the X-Stop device. No patients were involved in this study. No specific outcome measures were used. Search engines Google, Yahoo, and Bing were used to identify 105 web sites providing information on the X-Stop. Videos on the web site YouTube were included. Web sites were categorized based on the authorship. Each site was analyzed for the provision of appropriate patient inclusion and exclusion criteria, surgical and nonsurgical treatment alternatives, purported benefits, common complications, peer-reviewed literature citations, and descriptions/diagrams of the procedure. Data were evaluated for each authorship subgroup and the entire group of sites. Forty-three percent of sites were authored by a private medical group, 4% by an academic medical group, 16% by an insurance company, 9% by a biomedical industry, 10% by news sources, and 19% by other. Thirty-one percent of web sites and 11% of sites authored by private medical groups contained references to peer-reviewed literature. Fifty-six percent of web sites reported patient inclusion criteria, whereas 33% reported exclusion criteria. Benefits and complications were reported within 91% and 23% of sites, respectively. Surgical and nonsurgical treatment options were mentioned within 59% and 61% of web sites, respectively. Our study demonstrates the Internet's ineffectiveness in reporting quality information on the X-Stop. Information was often incomplete and potentially misleading. Significant controversy exists within primary literature regarding the safety and efficacy of the X-Stop. Yet, publicly available Internet information largely provided misinformation and did not reflect any such controversy. This raises the concern that such information lends itself more toward patient recruitment than patient education. Medical professionals need to know how this may affect their patients' decision making. Copyright © 2014 Elsevier Inc. All rights reserved.

Development of a Comprehensive Database System for Safety Analyst

PubMed Central

Paz, Alexander; Veeramisti, Naveen; Khanal, Indira; Baker, Justin

2015-01-01

This study addressed barriers associated with the use of Safety Analyst, a state-of-the-art tool that has been developed to assist during the entire Traffic Safety Management process but that is not widely used due to a number of challenges as described in this paper. As part of this study, a comprehensive database system and tools to provide data to multiple traffic safety applications, with a focus on Safety Analyst, were developed. A number of data management tools were developed to extract, collect, transform, integrate, and load the data. The system includes consistency-checking capabilities to ensure the adequate insertion and update of data into the database. This system focused on data from roadways, ramps, intersections, and traffic characteristics for Safety Analyst. To test the proposed system and tools, data from Clark County, which is the largest county in Nevada and includes the cities of Las Vegas, Henderson, Boulder City, and North Las Vegas, was used. The database and Safety Analyst together help identify the sites with the potential for safety improvements. Specifically, this study examined the results from two case studies. The first case study, which identified sites having a potential for safety improvements with respect to fatal and all injury crashes, included all roadway elements and used default and calibrated Safety Performance Functions (SPFs). The second case study identified sites having a potential for safety improvements with respect to fatal and all injury crashes, specifically regarding intersections; it used default and calibrated SPFs as well. Conclusions were developed for the calibration of safety performance functions and the classification of site subtypes. Guidelines were provided about the selection of a particular network screening type or performance measure for network screening. PMID:26167531

Surface chemistry characterization of hydrodesulfurization and methanol synthesis model nanocatalysts

NASA Astrophysics Data System (ADS)

Komarneni, Mallikharjuna Rao

Surface science investigations of model catalysts have contributed significantly to heterogeneous catalysis over the past several decades. The unique properties of nanomaterials are being exploited in catalysis for the development of highly active and selective catalysts. Surface science investigations of model catalysts such as inorganic fullerene-like (IF) nanoparticles (NP), inorganic nanotubes (INT), and the oxide-supported nanoclusters are included in this dissertation. Thermal desorption spectroscopy and molecular beam scattering were respectively utilized to study the adsorption kinetics and dynamics of gas phase molecules on catalyst surfaces. In addition, ambient pressure kinetics experiments were performed to characterize the catalytic activity of hydrodesulfurization (HDS) nanocatalysts. The nanocatalysts were characterized with a variety of techniques, including Auger electron spectroscopy, x-ray photoelectron spectroscopy, electron microscopy, and x-ray diffraction. The adsorption kinetics studies of thiophene on novel HDS catalysts provided the first evidence for the presence of different adsorption sites on INT-WS2. Additionally, the adsorption sites on IF-MoS2 NP and silica-supported Mo clusters (Mo/silica) were characterized. Furthermore, the C-S bond activation energy of thiophene on Mo/silica was determined. These studies finally led to the fabrication of Ni/Co coated INT-WS2, which showed good catalytic activity towards HDS of thiophene. The studies of methanol synthesis catalysts include the adsorption kinetics and dynamics studies of CO and CO2 on Cu/silica and silica-supported EBL-fabricated Cu/CuOx nanoclusters. The adsorption dynamics of CO on Cu/silica are modeled within the frame work of the capture zone model (CZM), and the active sites of the silica-supported Au/Cu catalysts are successfully mapped. Studies on EBL model catalysts identify the rims of the CuOx nanoclusters as catalytically active sites. This observation has implications for new methanol catalyst design.

Surgical Treatment of Metastatic Ovarian Tumors From Extragenital Primary Sites.

PubMed

Sal, Veysel; Demirkiran, Fuat; Topuz, Samet; Kahramanoglu, Ilker; Yalcin, Ibrahim; Bese, Tugan; Sozen, Hamdullah; Tokgozoglu, Nedim; Salihoglu, Yavuz; Turan, Hasan; Iyibozkurt, Cem; Kolomuc, Tugba; Sofiyeva, Nigar; Berkman, Sinan; Arvas, Macit

2016-05-01

The purpose of this study was to investigate the outcomes and prognostic factors of metastasectomy in patients with metastatic ovarian tumors from extragenital primary sites. All patients with pathologically confirmed metastatic ovarian tumors between January 1997 and June 2015 were included in this study. A total of 131 patients were identified. The data were obtained from the patients' medical records. Clinicopathological features were evaluated by both univariate and multivariate analyses. The primary sites were colorectal region (53.4%), stomach (26%), and breast (13%). Preoperative serum CA 125 and CA 19-9 levels were elevated in 29.4% and 39.8% of the patients, respectively. Cytoreductive surgery was performed in 41.2% of the patients. Seventy-three (55.7%) patients had no residual disease after surgery. Sixty-six (49.6%) patients had combined metastases at the time of the surgery to sites including the liver, pancreas, lung, bone, lymph nodes, bladder, or the intestine. With a median follow-up of 33 months, the median survival time was 22 months. The estimated 5-year survival probability is 0.26. On univariate analysis, primary cancer site, combined metastasis outside the ovaries, residual disease, preoperative serum CA 125 and CA 19-9 levels, and histologic type were significant parameters for overall survival. Furthermore, residual disease, preoperative serum CA 19-9 level, and primary cancer site were found to be independent prognostic factors on multivariate analysis. The most common primary sites for ovarian metastasis are gastrointestinal tract. Metastasectomy may have beneficial effects on survival, especially if the residual disease is less than 5 mm. Prospective studies warranted to evaluate the value of metastasectomy in patients with ovarian metastasis.

34 CFR 602.17 - Application of standards in reaching an accrediting decision.

Code of Federal Regulations, 2012 CFR

2012-07-01

... program to prepare, following guidance provided by the agency, an in-depth self-study that includes the... on-site review; (e) Conducts its own analysis of the self-study and supporting documentation... standards, including areas needing improvement; and (2) The institution's or program's performance with...

34 CFR 602.17 - Application of standards in reaching an accrediting decision.

Code of Federal Regulations, 2013 CFR

2013-07-01

... program to prepare, following guidance provided by the agency, an in-depth self-study that includes the... on-site review; (e) Conducts its own analysis of the self-study and supporting documentation... standards, including areas needing improvement; and (2) The institution's or program's performance with...

34 CFR 602.17 - Application of standards in reaching an accrediting decision.

Code of Federal Regulations, 2011 CFR

2011-07-01

... program to prepare, following guidance provided by the agency, an in-depth self-study that includes the... on-site review; (e) Conducts its own analysis of the self-study and supporting documentation... standards, including areas needing improvement; and (2) The institution's or program's performance with...

34 CFR 602.17 - Application of standards in reaching an accrediting decision.

Code of Federal Regulations, 2014 CFR

2014-07-01

... program to prepare, following guidance provided by the agency, an in-depth self-study that includes the... on-site review; (e) Conducts its own analysis of the self-study and supporting documentation... standards, including areas needing improvement; and (2) The institution's or program's performance with...

Feasibility Study of Economics and Performance of Solar Photovoltaics at the Vincent Mullins Landfill in Tucson, Arizona. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

DOE Office of Scientific and Technical Information (OSTI.GOV)

Steen, M.; Lisell, L.; Mosey, G.

2013-01-01

The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the Vincent Mullins Landfill in Tucson, Arizona, for a feasibility study of renewable energy production. Under the RE-Powering America's Land initiative, the EPA provided funding to the National Renewable Energy Laboratory (NREL) to support the study. NREL provided technical assistance for this project but did not assess environmental conditions at the site beyond those related to the performance of a photovoltaic (PV) system. The purpose of this report is to assess the site for a possible PV installation and estimate the cost and performance ofmore » different PV configurations, as well as to recommend financing options that could assist in the implementation of a PV system. In addition to the Vincent Mullins site, four similar landfills in Tucson are included as part of this study.« less

The eMERGE Network: a consortium of biorepositories linked to electronic medical records data for conducting genomic studies.

PubMed

McCarty, Catherine A; Chisholm, Rex L; Chute, Christopher G; Kullo, Iftikhar J; Jarvik, Gail P; Larson, Eric B; Li, Rongling; Masys, Daniel R; Ritchie, Marylyn D; Roden, Dan M; Struewing, Jeffery P; Wolf, Wendy A

2011-01-26

The eMERGE (electronic MEdical Records and GEnomics) Network is an NHGRI-supported consortium of five institutions to explore the utility of DNA repositories coupled to Electronic Medical Record (EMR) systems for advancing discovery in genome science. eMERGE also includes a special emphasis on the ethical, legal and social issues related to these endeavors. The five sites are supported by an Administrative Coordinating Center. Setting of network goals is initiated by working groups: (1) Genomics, (2) Informatics, and (3) Consent & Community Consultation, which also includes active participation by investigators outside the eMERGE funded sites, and (4) Return of Results Oversight Committee. The Steering Committee, comprised of site PIs and representatives and NHGRI staff, meet three times per year, once per year with the External Scientific Panel. The primary site-specific phenotypes for which samples have undergone genome-wide association study (GWAS) genotyping are cataract and HDL, dementia, electrocardiographic QRS duration, peripheral arterial disease, and type 2 diabetes. A GWAS is also being undertaken for resistant hypertension in ≈ 2,000 additional samples identified across the network sites, to be added to data available for samples already genotyped. Funded by ARRA supplements, secondary phenotypes have been added at all sites to leverage the genotyping data, and hypothyroidism is being analyzed as a cross-network phenotype. Results are being posted in dbGaP. Other key eMERGE activities include evaluation of the issues associated with cross-site deployment of common algorithms to identify cases and controls in EMRs, data privacy of genomic and clinically-derived data, developing approaches for large-scale meta-analysis of GWAS data across five sites, and a community consultation and consent initiative at each site. Plans are underway to expand the network in diversity of populations and incorporation of GWAS findings into clinical care. By combining advanced clinical informatics, genome science, and community consultation, eMERGE represents a first step in the development of data-driven approaches to incorporate genomic information into routine healthcare delivery.

Water-Quality Characteristics for Selected Sites Within the Milwaukee Metropolitan Sewerage District Planning Area, Wisconsin, February 2004-September 2005

USGS Publications Warehouse

Thomas, Judith C.; Lutz, Michelle A.; Bruce, Jennifer L.; Graczyk, David J.; Richards, Kevin D.; Krabbenhoft, David P.; Westenbroek, Stephen M.; Scudder, Barbara C.; Sullivan, Daniel J.; Bell, Amanda H.

2007-01-01

The Milwaukee Metropolitan Sewerage District (MMSD) Corridor Study is a three-phase project designed to improve the understanding of water resources in the MMSD planning area to assist managers and policy makers in their decisions. Phase I of the Study involved the compilation of existing data from multiple agencies into a single database. These data were analyzed to identify spatial, temporal, and technological gaps in the planning area, and were used to develop Phase II of the Study. Phase II, the subject of this report, involved an intensive data-collection effort by the U.S. Geological Survey (USGS) in cooperation with MMSD (from February, 2004, through September, 2005). This phase addressed the data gaps identified in Phase I and completed a baseline assessment of water quality for selected stream and harbor sites in the MMSD planning area. This baseline assessment included evaluations of surface-water chemistry and microbial concentrations in the streams and harbor sites; additionally, stream sites were evaluated for discharge, sediment chemistry, fish-tissue chemistry, habitat, and the quality of biological communities (including fish, macroinvertebrates, and algae). In all, data were collected at 15 stream and 6 harbor sites within the MMSD planning area, including manual sampling and analysis for more than 220 water-quality properties and constituents at all 21 sites, stream-discharge data for 14 stream sites, and automated water-quality sampling at 4 stream sites. A bioassessment during autumn 2004 included collection of biologic-community data and stream-habitat data at wadeable streams. Quartiles of Phase II aggregate bioassessment rankings were used to divide the 14 wadeable stream sites into four groups to investigate relations between bioassessment data and site characteristic and water-quality data. Quartile numbers reflect relative water quality: quartile 1 contained sites where the bioassessment data indicated the least-degraded water quality among those sampled, and quartile 4 contained sites that indicated the most-degraded water quality. Quartiles contained the following stream sites: Quartile 1: Milwaukee River near Cedarburg, Milwaukee River at Milwaukee, Jewel Creek, and Menomonee River at Menomonee Falls; Quartile 2: Willow Creek, Root River near Franklin, and Root River at Grange Avenue; Quartile 3: Menomonee River at Wauwatosa, Oak Creek, and Little Menomonee River; and Quartile 4: Honey Creek, Underwood Creek, Lincoln Creek, and Kinnickinnic River. Site characteristics (in this case, drainage area and land use) and selected water-quality data were summarized based on the four bioassessment quartiles to determine if there were relations with the aggregate bioassessment rankings. In general, sites having the largest drainage basins with the lowest proportion of urban land use were in quartile 1, and the smallest drainage basins with the highest proportion of urban land use were in quartile 4. Major ions, indicator organisms, and wastewater compounds generally had the lowest overall results in quartile 1 and highest overall results in quartile 4, with intermediate results in quartiles 2 and 3. Results for other constituent types (nutrients, mercury, pathogenic organisms, and bed sediment) were mixed, with results for some constituents decreasing from quartile 1 to quartile 4. Where sufficient Phase I data were available, summary statistics (including medians) for chemical and biological data were calculated, allowing some comparisons to be made between Phase I and Phase II data. Comparisons between Phase I and Phase II results indicated a variety of changes with respect to water quality. Concentrations of chloride, nitrate, chlorophyll a, total phosphorus in water; arsenic in bed sediment; and fish Index of Biotic Integrity ratings generally indicated declines in water quality. However, concentrations of total nitrogen, suspended sediment, and fecal coliform in water; some trace eleme

Superfund Record of Decision (EPA Region 4): Aberdeen Pesticide Dumps, Moore County, Aberdeen, NC. (First remedial action), (Amendment), September 1991

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-09-30

The Aberdeen Pesticide Dumps site consists of a plant area and four disposal areas in Aberdeen, Moore County, North Carolina. The five areas are Farm Chemicals, Twin Sites, Fairway Six, McIver Dump, and Route 211. Ground water is the main source of drinking water for local residents. After investigations by EPA's Emergency Response Section in 1985 and 1986, several removal actions were conducted, including removing surface contaminants, drums, and soil in several areas. The ROD concurrently addresses surface and subsurface soil contamination. The amended remedial action for this site includes conducting a treatability study using thermal desorption; excavating and treatingmore » a total of 123,933 cubic yards of soil from all five areas including previously excavated soil from the Fairway Six and McIver Dump areas using an onsite thermal desorption process that includes an activated carbon adsorption to treat off-gases, followed by offsite incineration of residual organics.« less

Modeling uranium(VI) adsorption onto montmorillonite under varying carbonate concentrations: A surface complexation model accounting for the spillover effect on surface potential

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tournassat, C.; Tinnacher, R. M.; Grangeon, S.

The prediction of U(VI) adsorption onto montmorillonite clay is confounded by the complexities of: (1) the montmorillonite structure in terms of adsorption sites on basal and edge surfaces, and the complex interactions between the electrical double layers at these surfaces, and (2) U(VI) solution speciation, which can include cationic, anionic and neutral species. Previous U(VI)-montmorillonite adsorption and modeling studies have typically expanded classical surface complexation modeling approaches, initially developed for simple oxides, to include both cation exchange and surface complexation reactions. However, previous models have not taken into account the unique characteristics of electrostatic surface potentials that occur at montmorillonitemore » edge sites, where the electrostatic surface potential of basal plane cation exchange sites influences the surface potential of neighboring edge sites (‘spillover’ effect).« less

Modeling uranium(VI) adsorption onto montmorillonite under varying carbonate concentrations: A surface complexation model accounting for the spillover effect on surface potential

DOE PAGES

Tournassat, C.; Tinnacher, R. M.; Grangeon, S.; ...

2017-10-06

The prediction of U(VI) adsorption onto montmorillonite clay is confounded by the complexities of: (1) the montmorillonite structure in terms of adsorption sites on basal and edge surfaces, and the complex interactions between the electrical double layers at these surfaces, and (2) U(VI) solution speciation, which can include cationic, anionic and neutral species. Previous U(VI)-montmorillonite adsorption and modeling studies have typically expanded classical surface complexation modeling approaches, initially developed for simple oxides, to include both cation exchange and surface complexation reactions. However, previous models have not taken into account the unique characteristics of electrostatic surface potentials that occur at montmorillonitemore » edge sites, where the electrostatic surface potential of basal plane cation exchange sites influences the surface potential of neighboring edge sites (‘spillover’ effect).« less

Design and methods of the Midwest Stream Quality Assessment (MSQA), 2013

USGS Publications Warehouse

Garrett, Jessica D.; Frey, Jeffrey W.; Van Metre, Peter C.; Journey, Celeste A.; Nakagaki, Naomi; Button, Daniel T.; Nowell, Lisa H.

2017-10-18

During 2013, the U.S. Geological Survey (USGS) National Water-Quality Assessment Project (NAWQA), in collaboration with the USGS Columbia Environmental Research Center, the U.S. Environmental Protection Agency (EPA) National Rivers and Streams Assessment (NRSA), and the EPA Office of Pesticide Programs assessed stream quality across the Midwestern United States. This Midwest Stream Quality Assessment (MSQA) simultaneously characterized watershed and stream-reach water-quality stressors along with instream biological conditions, to better understand regional stressor-effects relations. The MSQA design focused on effects from the widespread agriculture in the region and urban development because of their importance as ecological stressors of particular concern to Midwest region resource managers.A combined random stratified selection and a targeted selection based on land-use data were used to identify and select sites representing gradients in agricultural intensity across the region. During a 14-week period from May through August 2013, 100 sites were selected and sampled 12 times for contaminants, nutrients, and sediment. This 14-week water-quality “index” period culminated with an ecological survey of habitat, periphyton, benthic macroinvertebrates, and fish at all sites. Sediment was collected during the ecological survey for analysis of sediment chemistry and toxicity testing. Of the 100 sites, 50 were selected for the MSQA random stratified group from 154 NRSA sites planned for the region, and the other 50 MSQA sites were selected as targeted sites to more evenly cover agricultural and urban stressor gradients in the study area. Of the 50 targeted sites, 12 were in urbanized watersheds and 21 represented “good” biological conditions or “least disturbed” conditions. The remaining 17 targeted sites were selected to improve coverage of the agricultural intensity gradient or because of historical data collection to provide temporal context for the study.This report provides a detailed description of the MSQA study components, including surveys of ecological conditions, routine water sampling, deployment of passive polar organic compound integrative samplers, and stream sediment sampling at all sites. Component studies that were completed to provide finer scale temporal data or more extensive analysis at selected sites, included continuous water-quality monitoring, daily pesticide sampling, laboratory and in-stream water toxicity testing efforts, and deployment of passive suspended-sediment samplers.

Tunable electrical conductivity in metal-organic framework thin film devices

DOEpatents

Talin, Albert Alec; Allendorf, Mark D.; Stavila, Vitalie; Leonard, Francois

2016-08-30

A composition including a porous metal organic framework (MOF) including an open metal site and a guest species capable of charge transfer that can coordinate with the open metal site, wherein the composition is electrically conductive. A method including infiltrating a porous metal organic framework (MOF) including an open metal site with a guest species that is capable of charge transfer; and coordinating the guest species to the open metal site to form a composition including an electrical conductivity greater than an electrical conductivity of the MOF.

Tunable electrical conductivity in metal-organic framework thin film devices

DOEpatents

Talin, Albert Alec; Allendorf, Mark D.; Stavila, Vitalie; Leonard, Francois

2016-05-24

A composition including a porous metal organic framework (MOF) including an open metal site and a guest species capable of charge transfer that can coordinate with the open metal site, wherein the composition is electrically conductive. A method including infiltrating a porous metal organic framework (MOF) including an open metal site with a guest species that is capable of charge transfer; and coordinating the guest species to the open metal site to form a composition including an electrical conductivity greater than an electrical conductivity of the MOF.

Modeling of site occupancy dynamics for northern spotted owls, with emphasis on the effects of barred owls

USGS Publications Warehouse

Olson, Gail S.; Anthony, Robert G.; Forsman, Eric D.; Ackers, Steven H.; Loschl, Peter J.; Reid, Janice A.; Dugger, Katie M.; Glenn, Elizabeth M.; Ripple, William J.

2005-01-01

Northern spotted owls (Strix occidentalis caurina) have been studied intensively since their listing as a threatened species by the U.S. Fish and Wildlife Service in 1990. Studies of spotted owl site occupancy have used various binary response measures, but most of these studies have made the assumption that detectability is perfect, or at least high and not variable. Further, previous studies did not consider temporal variation in site occupancy. We used relatively new methods for open population modeling of site occupancy that incorporated imperfect and variable detectability of spotted owls and allowed modeling of temporal variation in site occupancy, extinction, and colonization probabilities. We also examined the effects of barred owl (S. varia) presence on these parameters. We used spotted owl survey data from 1990 to 2002 for 3 study areas in Oregon, USA, and we used program MARK to develop and analyze site occupancy models. We found per visit detection probabilities averaged <0.70 and were highly variable among study years and study areas. Site occupancy probabilities for owl pairs declined greatly on 1 study area and slightly on the other 2 areas. For all owls, including singles and pairs, site occupancy was mostly stable through time. Barred owl presence had a negative effect on spotted owl detection probabilities, and it had either a positive effect on local-extinction probabilities or a negative effect on colonization probabilities. We conclude that further analyses of spotted owls must account for imperfect and variable detectability and barred owl presence to properly interpret results. Further, because barred owl presence is increasing within the range of northern spotted owls, we expect to see further declines in the proportion of sites occupied by spotted owls.

Application of Geographic Information System and Remotesensing in effective solid waste disposal sites selection in Wukro town, Tigray, Ethiopia

NASA Astrophysics Data System (ADS)

Mohammedshum, A. A.; Gebresilassie, M. A.; Rulinda, C. M.; Kahsay, G. H.; Tesfay, M. S.

2014-11-01

Identifying solid waste disposal sites and appropriately managing them is a challenging task to many developing countries. This is a critical problem too in Ethiopia in general and in Wukro town in particular. The existing site for Wukro town is not sufficient in its capacity and it is damaging the environment due to its location, and the type of waste dumped, while the surrounding area is being irrigated. Due to the swift expansion and urbanization developments in Wukro town, it badly needs to develop controlled solid waste dumping site to prevent several contamination problems. This study was conducted first, to assess the existing waste management strategies in Wukro town; and second, to find out the potential waste disposal sites for the town, using GIS and Remote Sensing techniques. The study exploited the Multi-Criteria Evaluation (MCE) methods to combine necessary factors considered for dumping site selection. The selected method also uses various geographical data including remote sensing data, with GIS spatial analysis tools. Accordingly, site suitability maps for each of the factors were developed in a GIS environment. Results indicate that 12 dumping sites were appropriate and they were further ranked against their suitability in terms of wind direction, proximity to settlement area and distance from the center of the town. Finally, two sites are the best suitable for dumping site. This study indicated that the application of Geographic Information System and Remote Sensing techniques are efficient and low cost tools to study and select appropriate dumping site so as to facilitate decision making processes.

2008 Weather and Aeolian Sand-Transport Data from the Colorado River Corridor, Grand Canyon, Arizona

USGS Publications Warehouse

Draut, Amy E.; Sondossi, Hoda A.; Hazel, Joseph E.; Andrews, Timothy; Fairley, Helen C.; Brown, Christopher R.; Vanaman, Karen M.

2009-01-01

This report presents measurements of weather parameters and aeolian (windblown) sand transport made in 2008 near selected archaeological sites in the Colorado River corridor through Grand Canyon, Ariz. The quantitative methods and data discussed here form a basis for monitoring ecosystem processes that affect archeological-site stability. Combined with forthcoming work to evaluate landscape evolution at nearby archaeological sites, these data can be used to document the relationship between physical processes, including weather and aeolian sand transport, and their effects on the physical integrity of archaeological sites. Data collected in 2008 reveal event- and seasonal-scale variations in rainfall, wind, temperature, humidity, and barometric pressure. Broad seasonal changes in aeolian sediment flux are also apparent at most study sites. The continuation of monitoring that began in 2007, and installation of equipment at several new sites in early 2008, allowed evaluation of the effects of the March 2008 high-flow experiment (HFE) on aeolian sand transport. At two of the nine sites studied, spring and summer winds reworked 2008 HFE sandbars to form new aeolian dunes, at which sand moved inland toward larger, well-established dune fields. At the other seven study sites, neither dune formation nor enhanced sand transport after the HFE were observed. At several of those sites, dominant wind directions in spring 2008 were not oriented such that much HFE sand would have moved inland; at other sites, lack of increased inland sand flux is attributable to lack of sandbar enlargement near the study sites or to inhibition of sand movement by vegetation or local topography.

PhosphoSitePlus, 2014: mutations, PTMs and recalibrations

PubMed Central

Hornbeck, Peter V.; Zhang, Bin; Murray, Beth; Kornhauser, Jon M.; Latham, Vaughan; Skrzypek, Elzbieta

2015-01-01

PhosphoSitePlus® (PSP, http://www.phosphosite.org/), a knowledgebase dedicated to mammalian post-translational modifications (PTMs), contains over 330 000 non-redundant PTMs, including phospho, acetyl, ubiquityl and methyl groups. Over 95% of the sites are from mass spectrometry (MS) experiments. In order to improve data reliability, early MS data have been reanalyzed, applying a common standard of analysis across over 1 000 000 spectra. Site assignments with P > 0.05 were filtered out. Two new downloads are available from PSP. The ‘Regulatory sites’ dataset includes curated information about modification sites that regulate downstream cellular processes, molecular functions and protein-protein interactions. The ‘PTMVar’ dataset, an intersect of missense mutations and PTMs from PSP, identifies over 25 000 PTMVars (PTMs Impacted by Variants) that can rewire signaling pathways. The PTMVar data include missense mutations from UniPROTKB, TCGA and other sources that cause over 2000 diseases or syndromes (MIM) and polymorphisms, or are associated with hundreds of cancers. PTMVars include 18 548 phosphorlyation sites, 3412 ubiquitylation sites, 2316 acetylation sites, 685 methylation sites and 245 succinylation sites. PMID:25514926

Seasonal distribution of bird populations at the Patuxent Research Refuge

USGS Publications Warehouse

Hoffman, D.J.; Henny, C.J.; Hill, E.F.; Keith, J.A.; Grove, R.A.

2000-01-01

High concentrations of mercury from past mining activities have accumulated in the food chain of fish-eating birds nesting along the mid to lower Carson River. Activities of nine plasma and tissue enzymes, and concentrations of other plasma and tissue constituents were measured for black-crowned night-heron, Nycticorax nycticorax, (BCNH) and snowy egret, Egretta thula, (SE) nestlings from two high mercury sites and one low mercury site. Geometric mean blood Hg concentrations for BCNHs at the high mercury sites were 2.6 and 2.8 ppm (ww) and 0.6 ppm at the low mercury site. Blood concentrations for SEs were 3.6 and 1.9 ppm at the high mercury sites and 0.7 ppm at the low mercury site. In BCNHs plasma glutathione peroxidase (GSH peroxidase) activity was lower in both high mercury sites relative to the low mercury site. Butyryl cholinesterase (BuChe), ALT, glutathione reductase (GSSG-reductase) and LDH-L activities were lower in one high mercury site. In SEs significant differences were lower BuChe and LDH-L, but elevated GGT activities. Evidence of renal stress in both species at high mercury sites included increased plasma uric acid, blood urea nitrogen, and creatinine concentrations as well as oxidative stress in the kidney tissue itself where oxidized glutathione increased. A number of the mercury site-related effects, including decreased plasma GSH-peroxidase and hepatic G-6-PDH activities, higher GSSG-reductase activity, and lower hepatic concentrations of reduced thiols have been reported in methylmercury feeding studies with great egrets and mallards. These findings suggest the utility of herons and egrets for monitoring mercury sites.

Geologic setting and water quality of selected basins in the active coal-mining areas of Ohio, 1989-91, with a summary of water quality for 1985-91

USGS Publications Warehouse

Sedam, A.C.; Francy, D.S.

1993-01-01

This report presents streamwater- and ground-water-quality data collected to characterize the baseline water quality for 21 drainage basins in the coal-mining region of eastern Ohio. The study area is mostly within the unglaciated part of eastern Ohio along the western edge of the Appalachian Plateaus Physiographic Province. The data collected from 1989-91 and presented in this report represent the third and final phase of a 7-year study to assess baseline water quality in Ohio's coal region during 1985-1991. During 1989-91, 246 samples from 41 streamwater sites were collected periodically from a long-term site network. Ranges and medians of measurements made at the long-term streamwater sites were following: specific conductance, 270 to 5,170 and 792 microsiemens per centimeter at 25 degrees Celsius; pH, 2.7 to 9.1 and 7.8; alkalinity, 1 to 391 and 116 mg/L (milligrams per liter). Ranges and medians of laboratory analyses of the same samples were the following: dissolved sulfate, 13 to 2,100 and 200 mg/L; dissolved aluminum, <10 to 17,000 and 300 ? /L (micrograms per liter); dissolved iron, <10 to 53,000 and 60 ? /L; and dissolved manganese, <10 to 17,000 and 295 ? /L. The ranges for concentrations of total recoverable aluminum, iron, and manganese were similar to the ranges of concentrations found for dissolved constituents. Medians of total recoverable aluminum and iron were about 10 times greater than the medians of dissolved aluminum and iron. During 1989-91, once-only sample collections were done at 45 streamwater sites in nine basins chosen for synoptic sampling. At several sites in the Middle Hocking River basin and Leading Creek basin, water had low pH and high concentrations of dissolved aluminum, iron and manganese. These water-quality characteristics are commonly associated with ace mine drainage. Throughout the entire 7-year study (1985-91), medians for most constituents at the long-term streamwater-sampling sites were fairly consistent, despite the geographic diversity of the study area. Waters from several long-term sites, including several sites in Moxahala Creek and Middle Hocking River basins, had low pH and high concentrations of several constituents, including dissolved sulfate, iron, aluminum, and manganese; this combinations characteristics is indicitive of acid drainage from surface-mining operations. At many of the streamwater sites where concentration of these constituents were high, pH values in the neutral or alkaline range were indicative of stream buffering by carbonate rock or restoration of mined lands in the drainage system. The basins with sites in this category include Yellow and Cross Creeks and Wheeling Creek basins. Water quality at other sites showed little or no effects from surface mining. Ground-water samples collected during the last phase of the study (1989-91) were mostly from unconsolidated aquifers. The waters were generally hard to very hard and calcium bicarbonate in type. During the entire 7-year study period, medians of pH in ground-water samples varied little, and most values were in the alkaline range. Except for a few sites where concentrations of dissolved sulfate exceeded 250 mg/L and concentrations of total recoverable and dissolved iron and manganese exceeded 1,000 ? /L, the quality of ground water at the wells sampled in the study area showed little effect from coal mining.

Nuclear facility decommissioning and site remedial actions: A selected bibliography, volume 9

DOE Office of Scientific and Technical Information (OSTI.GOV)

Owen, P.T.; Knox, N.P.; Michelson, D.C.

1988-09-01

The 604 abstracted references on nuclear facility decommissioning, uranium mill tailings management, and site remedial actions constitute the ninth in a series of reports prepared annually for the US Department of Energy's Remedial Action Programs. Foreign and domestic literature of all types--technical reports, progress reports, journal articles, symposia proceedings, theses, books, patents, legislation, and research project descriptions--has been included. The bibliography contains scientific, technical, economic, regulatory, and legal information pertinent to the US Department of Energy's remedial action programs. Major sections are (1) Surplus Facilities Management Program, (2) Nuclear Facilities Decommissioning, (3) Formerly Utilized Sites Remedial Action Program, (4) Facilitiesmore » Contaminated with Naturally Occurring Radionuclides, (5) Uranium Mill Tailings Remedial Action Program, (6) Uranium Mill Tailings Management, (7) Technical Measurements Center, and (8) General Remedial Action Program Studies. Subsections for sections 1, 2, 5, and 6 include: Design, Planning, and Regulations; Environmental Studies and Site Surveys; Health, Safety, and Biomedical Studies; Decontamination Studies; Dismantlement and Demolition; Site Stabilization and Reclamation; Waste Disposal; Remedial Action Experience; and General Studies. Within these categories, references are arranged alphabetically by first author. Those references having no individual author are listed by corporate affiliation or by publication description. Indexes are provided for author, corporate affiliation, title word, publication description, geographic location, and keywords. This report is a product of the Remedial Action Program Information Center (RAPIC), which selects and analyzes information on remedial actions and relevant radioactive waste management technologies. RAPIC staff and resources are available to meet a variety of information needs. Contact the center at (615) 576-0568 or FTS 626-0568.« less

Guide for Identifying and Converting High-Potential Petroleum Brownfield Sites to Alternative Fuel Stations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, C.; Hettinger, D.; Mosey, G.

Former gasoline stations that are now classified as brownfields can be good sites to sell alternative fuels because they are in locations that are convenient to vehicles and they may be seeking a new source of income. However, their success as alternative fueling stations is highly dependent on location-specific criteria. First, this report outlines what these criteria are, how to prioritize them, and then applies that assessment framework to five of the most popular alternative fuels--electricity, natural gas, hydrogen, ethanol, and biodiesel. The second part of this report delves into the criteria and tools used to assess an alternative fuelmore » retail site at the local level. It does this through two case studies of converting former gasoline stations in the Seattle-Eugene area into electric charge stations. The third part of this report addresses steps to be taken after the specific site has been selected. This includes choosing and installing the recharging equipment, which includes steps to take in the permitting process and key players to include.« less

Life-threatening methemoglobinemia after unintentional ingestion of antifreeze admixtures containing sodium nitrite in the construction sites.

PubMed

Sohn, C H; Seo, D W; Ryoo, S M; Lee, J H; Kim, W Y; Lim, K S; Oh, B J

2014-01-01

Construction workers are exposed to a wide variety of health hazards such as poisoning at the construction sites. Various forms of poisoning incidents in construction workers have been reported. However, studies on methemoglobinemia caused by unintentional ingestion of antifreeze admixtures containing sodium nitrite at the construction sites have not been reported yet. The aim of this study was to evaluate life-threatening methemoglobinemia after unintentional ingestion of antifreeze admixtures containing sodium nitrite at the construction sites and describe similar incidents involving ingestion of antifreeze admixtures in Korea. Retrospective observational case series study on patients with methemoglobinemia after unintentional ingestion of antifreeze admixtures containing sodium nitrite admitted to the emergency department (ED) from January 1, 2010 to December 31, 2012 and cases reported to the Korea Occupational Safety and Health Agency (KOSHA) was performed. Results. Six victims were admitted to our ED. They had methemoglobin levels ranging from 32.4% to 71.5% and all of them recovered after receiving one (2 mg/kg) or two doses infusion of methylene blue. From the data of the KOSHA, six incidents that caused 27 victims were identified. Of 27 victims, five were included in the ED cases. For all incidents, antifreeze admixtures were not contained in their original containers and all new containers did not have a new label. All workers mistook antifreeze admixtures for water. Among the 28 victims included in this study, four died. Unintentional ingestion of antifreeze admixtures containing sodium nitrite at the construction sites can cause life-threatening methemoglobinemia. There is a need to store and label potentially hazardous materials properly to avoid unintentional ingestion at the construction sites.

Reconnaissance evaluation of surface-water quality in Eagle, Grand, Jackson, Pitkin, Routt, and Summit counties, Colorado

USGS Publications Warehouse

Britton, Linda J.

1979-01-01

Water-quality data were collected from streams in a six-county area in northwest Colorado to determine if the streams were polluted and, if so, to determine the sources of the pollution. Eighty-three stream sites were selected for sampling in Eagle, Grand, Jackson, Pitkin, Routt, and Summit Counties. A summary of data collected prior to this study, results of current chemical and biological sampling, and needs for future water-quality monitoring are reported for each county. Data collected at selected sites included temperature, pH, specific conductance, dissolved oxygen, and stream discharge. Chemical data collected included nutrients, inorganics, organics, and trace elements. Biological data collected included counts and species composition of total and fecal-coliform bacteria, fecal-streptococcus bacteria, benthic invertebrates, and phytoplankton. Most of the sites were sampled three times: in April-June 1976, August 1976, and January 1977. (Woodard-USGS)

Selected environmental plutonium research reports of the NAEG

DOE Office of Scientific and Technical Information (OSTI.GOV)

White, M.G.; Dunaway, P.B.

Twenty-one papers were presented on various aspects of plutonium and radioisotope ecology at the Nevada Test Site. This includes studies of wildlife, microorganisms, and the plant-soil system. Analysis and sampling techniques are also included.

Site Selection for the Disposal of LLW in Taiwan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chuang, W.S.; Chi, L.M.; Tien, N.C.

2006-07-01

This paper presents the implementation status of the low-level radioactive waste (LLW) disposal program in Taiwan, including the disposal facility regulations, status of waste management, final disposal program, licensing procedures, waste acceptance criteria, site selection criteria and processes and preliminary disposal concepts. The first phase of site selection for low-level radioactive waste final disposal in Taiwan was implemented between 1992 and 2002. The site selection process adopted a Geographic Information System (GIS), Hierarchical Analysis System, Expert Evaluation System, and site reconnaissance. An incentive program for voluntary sites was also initiated. After a series of evaluations and discussion of 30 potentialmore » candidate sites, including 8 recommended sites, 5 qualified voluntary townships, and several remote uninhabited small islets, Hsiao-chiou islet was selected as the first priority candidate site in February 1998. The geological investigation work in Hsiao-chiou was conducted from March 1999 through October 2000. An Environmental Impact Statement Report (EIS) and the Investment Feasibility Study Report (IFS) were submitted to the Environmental Protection Agency (EPA) in November 2000 and to the Ministry of Economic Affairs (MOEA) in June 2001, respectively. Unfortunately, the site investigation was discontinued in 2002 due to political and public acceptance consideration. After years of planning, the second phase of the site selection process was launched in August 2004 and will be conducted through 2008. It is planned that a repository will be constructed in early 2009 and start to operate in 2014. The site selection process for the second phase is based on the earlier work and four potential candidate sites were selected for evaluation until 2005. A near surface disposal concept is proposed for a site located in the Taiwan strait, and cavern disposal concepts are proposed for three other sites located on the main island. This paper presents the implementation status of the LLW disposal program in Taiwan, including the disposal facility regulations, status of waste management, final disposal program, licensing procedures, waste acceptance criteria, site selection criteria and processes, and preliminary disposal concepts 'NIMBY' (Not in my backyard) is a critical problem for implementation of the final disposal project. Resistance from local communities has been continuously received during site characterization. To overcome this, an incentive program to encourage community acceptance has been approved by the Government. Programs for community promotion are being proposed and negotiations are also underway. (authors)« less

Accounting for age Structure in Ponderosa Pine Ecosystem Analyses: Integrating Management, Disturbance Histories and Observations with the BIOME-BGC Model

NASA Astrophysics Data System (ADS)

Hibbard, K. A.; Law, B.; Thornton, P.

2003-12-01

Disturbance and management regimes in forested ecosystems have been recently highlighted as important factors contributing to quantification of carbon stocks and fluxes. Disturbance events, such as stand-replacing fires and current management regimes that emphasize understory and tree thinning are primary suspects influencing ecosystem processes, including net ecosystem productivity (NEP) in forests of the Pacific Northwest. Several recent analyses have compared simulated to measured component stocks and fluxes of carbon in Ponderosa Pine (Pinus ponderosa var. Laws) at 12 sites ranging from 9 to 300 years in central Oregon (Law et al. 2001, Law et al. 2003) using the BIOME-BGC model. Major emphases on ecosystem model developments include improving allocation logic, integrating ecosystem processes with disturbance such as fire and including nitrogen in biogeochemical cycling. In Law et al. (2001, 2003), field observations prompted BIOME-BGC improvements including dynamic allocation of carbon to fine root mass through the life of a stand. A sequence of simulations was also designed to represent both management and disturbance histories for each site, however, current age structure of each sites wasn't addressed. Age structure, or cohort management has largely been ignored by ecosystem models, however, some studies have sought to incorporate stand age with disturbance and management (e.g. Hibbard et al. 2003). In this analyses, we regressed tree ages against height (R2 = 0.67) to develop a proportional distribution of age structure for each site. To preserve the integrity of the comparison between Law et al. (2003) and this study, we maintained the same timing of harvest, however, based on the distribution of age structures, we manipulated the amount of removal. Harvest by Law et al. (2003) was set at stand-replacement (99%) levels to simulate clear-cutting and reflecting the average top 10% of the age in each plot. For the young sites, we set removal at 73%, 51% and 61% for sites averaging 9,16 and 23 years, respectively. It was assumed that changes in long-term pools (e.g. soil C) were negligible within these timeframes. In Law et al. (2003), the model performed well for old and mature sites, however, model simulations of the younger sites (9-50Y) were weak compared to NEP estimates from observations. Error for the young plots in Law et al. (2003) ranged from 150 - >400% of observed NEP. By accounting for the observed age structure through harvest removal, model error from this study ranged from 20-90% in young plots. This study is one of a few that have sought to account for age structure in simulating ecosystem dynamics and processes.

76 FR 27366 - CEVA Freight, LLC, Dell Logistics Division, Including On-Site Leased Workers From Prologistix...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-11

... Logistics Division, Including On-Site Leased Workers From Prologistix, Including Workers Whose Unemployment..., applicable to workers of CEVA Freight, LLC, Dell Logistics Division, including on-site leased workers from... workers employed at CEVA Freight, LLC, Dell Logistics Division, Winston-Salem, North Carolina who were...

78 FR 61389 - Sanyo Solar of Oregon, LLC, Wafer Slicing and Quality Control Operations, Including On-Site...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-03

..., LLC, Wafer Slicing and Quality Control Operations, Including On-Site Leased Workers From Brown and... Quality Control Operations, Salem, Oregon, including on-site leased workers from Brown and Dunton, Inc... and included workers who supplied quality control and support functions. The company reports that...

Rapid assessment of environmental health risks posed by mining operations in low- and middle-income countries: selected case studies.

PubMed

Caravanos, Jack; Ericson, Bret; Ponce-Canchihuamán, Johny; Hanrahan, David; Block, Meredith; Susilorini, Budi; Fuller, Richard

2013-11-01

Previous studies have evaluated associated health risks and human exposure pathways at mining sites. Others have provided estimates of the scale of the issue based in part on surveys. However, a global census of mining-related hazardous waste sites has been lacking. The Toxic Sites Identification Program (TSIP) implemented by Blacksmith Institute (New York, NY, USA) since 2009 is an ongoing effort to catalogue a wide range of chemically contaminated sites with a potential human health risk (Ericson et al., Environ Monit Assess doi:10.1007/s 10661-012-2665-2, 2012). The TSIP utilizes a rapid assessment instrument, the Initial Site Screening (ISS), to quickly and affordably identify key site criteria including human exposure pathways, estimated populations at risk, and sampling information. The resulting ISS allows for comparison between sites exhibiting different contaminants and pollution sources. This paper explores the results of a subset of ISSs completed at 131 artisanal and small-scale gold mining areas and 275 industrial mining and ore processing sites in 45 countries. The authors show that the ISS captures key data points, allowing for prioritization of sites for further investigation or remedial activity.

Allosteric binding sites in Rab11 for potential drug candidates

PubMed Central

2018-01-01

Rab11 is an important protein subfamily in the RabGTPase family. These proteins physiologically function as key regulators of intracellular membrane trafficking processes. Pathologically, Rab11 proteins are implicated in many diseases including cancers, neurodegenerative diseases and type 2 diabetes. Although they are medically important, no previous study has found Rab11 allosteric binding sites where potential drug candidates can bind to. In this study, by employing multiple clustering approaches integrating principal component analysis, independent component analysis and locally linear embedding, we performed structural analyses of Rab11 and identified eight representative structures. Using these representatives to perform binding site mapping and virtual screening, we identified two novel binding sites in Rab11 and small molecules that can preferentially bind to different conformations of these sites with high affinities. After identifying the binding sites and the residue interaction networks in the representatives, we computationally showed that these binding sites may allosterically regulate Rab11, as these sites communicate with switch 2 region that binds to GTP/GDP. These two allosteric binding sites in Rab11 are also similar to two allosteric pockets in Ras that we discovered previously. PMID:29874286

NIMH Project Accept (HPTN 043): results from in-depth interviews with a longitudinal cohort of community members.

PubMed

Maman, Suzanne; van Rooyen, Heidi; Stankard, Petra; Chingono, Alfred; Muravha, Tshifhiwa; Ntogwisangu, Jacob; Phakathi, Zipho; Srirak, Namtip; F Morin, Stephen

2014-01-01

NIMH Project Accept (HPTN 043) is a community- randomized trial to test the safety and efficacy of a community-level intervention designed to increase testing and lower HIV incidence in Tanzania, Zimbabwe, South Africa and Thailand. The evaluation design included a longitudinal study with community members to assess attitudinal and behavioral changes in study outcomes including HIV testing norms, HIV-related discussions, and HIV-related stigma. A cohort of 657 individuals across all sites was selected to participate in a qualitative study that involved 4 interviews during the study period. Baseline and 30-month data were summarized according to each outcome, and a qualitative assessment of changes was made at the community level over time. Members from intervention communities described fewer barriers and greater motivation for testing than those from comparison communities. HIV-related discussions in intervention communities were more grounded in personal testing experiences. A change in HIV-related stigma over time was most pronounced in Tanzania and Zimbabwe. Participants in the intervention communities from these two sites attributed community-level changes in attitudes to project specific activities. The Project Accept intervention was associated with more favorable social norms regarding HIV testing, more personal content in HIV discussions in all study sites, and qualitative changes in HIV-related stigma in two of five sites.

Bioinformatic analysis of the effects and mechanisms of decitabine and cytarabine on acute myeloid leukemia

PubMed Central

Zhou, Shiyong; Liu, Pengfei; Zhang, Huilai

2017-01-01

Acute myeloid leukemia (AML) is a frequently occurring malignant disease of the blood and may result from a variety of genetic disorders. The present study aimed to identify the underlying mechanisms associated with the therapeutic effects of decitabine and cytarabine on AML, using microarray analysis. The microarray datasets GSE40442 and GSE40870 were downloaded from the Gene Expression Omnibus database. Differentially expressed genes (DEGs) and differentially methylated sites were identified in AML cells treated with decitabine compared with those treated with cytarabine via the Linear Models for Microarray Data package, following data pre-processing. Gene Ontology (GO) analysis of DEGs was performed using the Database for Annotation, Visualization and Integrated Analysis Discovery. Genes corresponding to the differentially methylated sites were obtained using the annotation package of the methylation microarray platform. The overlapping genes were identified, which exhibited the opposite variation trend between gene expression and DNA methylation. Important transcription factor (TF)-gene pairs were screened out, and a regulated network subsequently constructed. A total of 190 DEGs and 540 differentially methylated sites were identified in AML cells treated with decitabine compared with those treated with cytarabine. A total of 36 GO terms of DEGs were enriched, including nucleosomes, protein-DNA complexes and the nucleosome assembly. The 540 differentially methylated sites were located on 240 genes, including the acid-repeat containing protein (ACRC) gene that was additionally differentially expressed. In addition, 60 TF pairs and overlapped methylated sites, and 140 TF-pairs and DEGs were screened out. The regulated network included 68 nodes and 140 TF-gene pairs. The present study identified various genes including ACRC and proliferating cell nuclear antigen, in addition to various TFs, including TATA-box binding protein associated factor 1 and CCCTC-binding factor, which may be potential therapeutic targets of AML. PMID:28498449

Bioinformatic analysis of the effects and mechanisms of decitabine and cytarabine on acute myeloid leukemia.

PubMed

Zhou, Shiyong; Liu, Pengfei; Zhang, Huilai

2017-07-01

Acute myeloid leukemia (AML) is a frequently occurring malignant disease of the blood and may result from a variety of genetic disorders. The present study aimed to identify the underlying mechanisms associated with the therapeutic effects of decitabine and cytarabine on AML, using microarray analysis. The microarray datasets GSE40442 and GSE40870 were downloaded from the Gene Expression Omnibus database. Differentially expressed genes (DEGs) and differentially methylated sites were identified in AML cells treated with decitabine compared with those treated with cytarabine via the Linear Models for Microarray Data package, following data pre‑processing. Gene Ontology (GO) analysis of DEGs was performed using the Database for Annotation, Visualization and Integrated Analysis Discovery. Genes corresponding to the differentially methylated sites were obtained using the annotation package of the methylation microarray platform. The overlapping genes were identified, which exhibited the opposite variation trend between gene expression and DNA methylation. Important transcription factor (TF)‑gene pairs were screened out, and a regulated network subsequently constructed. A total of 190 DEGs and 540 differentially methylated sites were identified in AML cells treated with decitabine compared with those treated with cytarabine. A total of 36 GO terms of DEGs were enriched, including nucleosomes, protein‑DNA complexes and the nucleosome assembly. The 540 differentially methylated sites were located on 240 genes, including the acid‑repeat containing protein (ACRC) gene that was additionally differentially expressed. In addition, 60 TF pairs and overlapped methylated sites, and 140 TF‑pairs and DEGs were screened out. The regulated network included 68 nodes and 140 TF‑gene pairs. The present study identified various genes including ACRC and proliferating cell nuclear antigen, in addition to various TFs, including TATA‑box binding protein associated factor 1 and CCCTC‑binding factor, which may be potential therapeutic targets of AML.

Cigars, youth, and the Internet link.

PubMed Central

Malone, R E; Bero, L A

2000-01-01

OBJECTIVES: This study examined the accessibility and appeal to youth of cigar marketing sites on the Internet. METHODS: Sites marketing cigars (n = 141) were examined for age restrictions, prices, health warnings, and other elements. RESULTS: Although it is illegal for minors to purchase tobacco, only 36 sites (25.5%) prohibited purchases by minors. Sites offered low prices, and 32% accepted money orders, cashier's checks, or cash-on-delivery (COD) orders. Almost 30% of the sites included elements with potential youth appeal; only 3.5% displayed health warnings. CONCLUSIONS: The unregulated promotion of cigars on the Internet has the potential to attract youth, and there are few barriers to Internet tobacco purchases by minors. PMID:10800432

Strategies to Support Recruitment of Patients with Life-limiting illness for Research: The Palliative Care Research Cooperative Group

PubMed Central

Hanson, Laura C.; Bull, Janet; Wessell, Kathryn; Massie, Lisa; Bennett, Rachael E.; Kutner, Jean S.; Aziz, Noreen M.; Abernethy, Amy

2014-01-01

Context The Palliative Care Research Cooperative group (PCRC) is the first clinical trials cooperative for palliative care in the United States. Objectives To describe barriers and strategies for recruitment during the inaugural PCRC clinical trial. Methods The parent study was a multi-site randomized controlled trial enrolling adults with life expectancy anticipated to be 1–6 months, randomized to discontinue statins (intervention) vs. to continue on statins (control). To study recruitment best practices, we conducted semi-structured interviews with 18 site Principal Investigators (PI) and Clinical Research Coordinators (CRC), and reviewed recruitment rates. Interviews covered 3 topics – 1) successful strategies for recruitment, 2) barriers to recruitment, and 3) optimal roles of the PI and CRC. Results All eligible site PIs and CRCs completed interviews and provided data on statin protocol recruitment. The parent study completed recruitment of n=381 patients. Site enrollment ranged from 1–109 participants, with an average of 25 enrolled per site. Five major barriers included difficulty locating eligible patients, severity of illness, family and provider protectiveness, seeking patients in multiple settings, and lack of resources for recruitment activities. Five effective recruitment strategies included systematic screening of patient lists, thoughtful messaging to make research relevant, flexible protocols to accommodate patients’ needs, support from clinical champions, and the additional resources of a trials cooperative group. Conclusion The recruitment experience from the multi-site PCRC yields new insights into methods for effective recruitment to palliative care clinical trials. These results will inform training materials for the PCRC and may assist other investigators in the field. PMID:24863152

40 CFR 35.4070 - How can my group spend TAG money?

Code of Federal Regulations, 2011 CFR

2011-07-01

... investigation, and feasibility study, record of decision, remedial design, selection and construction of... and maintenance” of a site, including exposure investigation, health study, surveillance program...

Critical management practices influencing on-site waste minimization in construction projects.

PubMed

Ajayi, Saheed O; Oyedele, Lukumon O; Bilal, Muhammad; Akinade, Olugbenga O; Alaka, Hafiz A; Owolabi, Hakeem A

2017-01-01

As a result of increasing recognition of effective site management as the strategic approach for achieving the required performance in construction projects, this study seeks to identify the key site management practices that are requisite for construction waste minimization. A mixed methods approach, involving field study and survey research were used as means of data collection. After confirmation of construct validity and reliability of scale, data analysis was carried out through a combination of Kruskal-Wallis test, descriptive statistics and exploratory factor analysis. The study suggests that site management functions could significantly reduce waste generation through strict adherence to project drawings, and by ensuring fewer or no design changes during construction process. Provision of waste skips for specific materials and maximisation of on-site reuse of materials are also found to be among the key factors for engendering waste minimization. The result of factor analysis suggests four factors underlying on-site waste management practices with 96.093% of total variance. These measures include contractual provisions for waste minimization, waste segregation, maximisation of materials reuse and effective logistic management. Strategies through which each of the underlying measures could be achieved are further discussed in the paper. Findings of this study would assist construction site managers and other site operatives in reducing waste generated by construction activities. Copyright © 2016 Elsevier Ltd. All rights reserved.

Comparison of CyTOF assays across sites: Results of a six-center pilot study.

PubMed

Leipold, Michael D; Obermoser, Gerlinde; Fenwick, Craig; Kleinstuber, Katja; Rashidi, Narges; McNevin, John P; Nau, Allison N; Wagar, Lisa E; Rozot, Virginie; Davis, Mark M; DeRosa, Stephen; Pantaleo, Giuseppe; Scriba, Thomas J; Walker, Bruce D; Olsen, Lars R; Maecker, Holden T

2018-02-01

For more than five years, high-dimensional mass cytometry has been employed to study immunology. However, these studies have typically been performed in one laboratory on one or few instruments. We present the results of a six-center study using healthy control human peripheral blood mononuclear cells (PBMCs) and commercially available reagents to test the intra-site and inter-site variation of mass cytometers and operators. We used prestained controls generated by the primary center as a reference to compare against samples stained at each individual center. Data were analyzed at the primary center, including investigating the effects of two normalization methods. All six sites performed similarly, with CVs for both Frequency of Parent and median signal intensity (MSI) values<30%. Increased background was seen when using the premixed antibody cocktail aliquots at each site, suggesting that cocktails are best made fresh. Both normalization methods tested performed adequately for normalizing MSI values between centers. Clustering algorithms revealed slight differences between the prestained and the sites-stained samples, due mostly to the increased background of a few antibodies. Therefore, we believe that multicenter mass cytometry assays are feasible. Copyright © 2017 The Author(s). Published by Elsevier B.V. All rights reserved.

Quality of water in the White River and Lake Tapps, Pierce County, Washington, May-December 2010

USGS Publications Warehouse

Embrey, S.S.; Wagner, R.J.; Huffman, R.L.; Vanderpool-Kimura, A. M.; Foreman, J.R.

2012-01-01

Water samples collected at the Allan Yorke, Snag Island, and Lake Outlet study sites were screened for the presence of more than 250 organic chemicals. A total of 14 compounds were detected in trace amounts (or determined to be present) at one or more of the 3 sites. The Allan Yorke site had 9 detections, the Snag Island site had 10 detections, and the Lake Outlet site had 5 detections of compounds mostly belonging to the group of wastewater indicator chemicals. Compounds detected (or with verified presence) at all three sites included the herbicide 2,4-D, the insecticide and mosquito repellant DEET, the herbicide fluridone used for Eurasian watermilfoil eradication, and the herbicide prometon. The largest concentrations of these compounds were in samples from the Allan Yorke site; the lowest concentrations were from the Lake Outlet site.

Relationship between peripheral insertion site and catheter-related phlebitis in adult hospitalized patients: a systematic review.

PubMed

Comparcini, Dania; Simonetti, Valentina; Blot, Stijn; Tomietto, Marco; Cicolini, Giancarlo

2017-01-01

To explore the relationship between the anatomical site of peripheral venous catheterization and risk of catheter-related phlebitis. Peripheral venous catheterization is frequently associated with phlebitis. Recent guidelines, recommend the use of an upper-extremity site for catheter insertion but no univocal consensus exists on the anatomical site with lower risk of phlebitis. Systematic review. We searched Medline (PubMed) and CINAHL (EBSCOhost) databases until the end of January 2017. We also reviewed the reference lists of retrieved articles and gray literature was excluded. Searches were limited to articles published in English with no restriction imposed to date of publication. The primary outcome was the incidence of phlebitis associated with anatomical site of peripheral catheterization. We included randomized controlled trials and observational studies on adult patients who required a peripheral catheter for the administration of medi- cation, intermittent or continuous fluid infusion. Antecubital fossa veins are associated with lower phlebitis rates, while hands veins are the most risky sites to develop phlebitis. There is no consensus regarding vein in forearm. Choosing the right anatomical site to insert a peripheral venous catheter is important to decrease phlebitis rate. Further studies should compare indwelling time in different anatomical sites with phlebitis rate. A more standardized approach in defining and assessing phlebitis among studies is recommended.

United States Air Force 611th Air Support Group/Civil Engineering Squadron Elmendorf AFB, Alaska. Remedial investigation and feasibility study. Barter Island Radar Installation, Alaska. Volume 1 (includes appendices a through c). Revision 1. Final report, January 1995-January 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

Karmi, S.; Madden, J.; Borsetti, R.

1996-01-05

This report presents the findings of Remedial Investigations and Feasibility Studies at sites located at the Barter Island radar installation in northern Alaska. The sites were characterized based on sampling and analyses conducted during Remedial Investigation activities performed during August and September 1993.

A Randomized Effectiveness Trial of a Systems Level Approach to Stepped Care for War Related PTSD

DTIC Science & Technology

2015-09-01

treatment options, STEPS UP includes web- based cognitive behavioral self- management, telephone cognitive-behavioral therapy , continuous RN nurse...IRB closure report packages for the Ft. Campbell and Ft. Stewart sites because study activities are no longer physically occurring at the study sites...significantly associated with decreased physical symptom burden (as measured by the PHQ-15), improved mental health functioning (as measured by the SF

Riparian and Associated Habitat Characteristics Related to Nutrient Concentrations and Biological Responses of Small Streams in Selected Agricultural Areas, United States, 2003-04

USGS Publications Warehouse

Zelt, Ronald B.; Munn, Mark D.

2009-01-01

Physical factors, including both in-stream and riparian habitat characteristics that limit biomass or otherwise regulate aquatic biological condition, have been identified by previous studies. However, linking the ecological significance of nutrient enrichment to habitat or landscape factors that could allow for improved management of streams has proved to be a challenge in many regions, including agricultural landscapes, where many ecological stressors are strong and the variability among watersheds typically is large. Riparian and associated habitat characteristics were sampled once during 2003-04 for an intensive ecological and nutrients study of small perennial streams in five contrasting agricultural landscapes across the United States to determine how biological communities and ecosystem processes respond to varying levels of nutrient enrichment. Nutrient concentrations were determined in stream water at two different sampling times per site and biological samples were collected once per site near the time of habitat characterization. Data for 141 sampling sites were compiled, representing five study areas, located in parts of the Delmarva Peninsula (Delaware and Maryland), Georgia, Indiana, Ohio, Nebraska, and Washington. This report examines the available data for riparian and associated habitat characteristics to address questions related to study-unit contrasts, spatial scale-related differences, multivariate correlation structure, and bivariate relations between selected habitat characteristics and either stream nutrient conditions or biological responses. Riparian and associated habitat characteristics were summarized and categorized into 22 groups of habitat variables, with 11 groups representing land-use and land-cover characteristics and 11 groups representing other riparian or in-stream habitat characteristics. Principal components analysis was used to identify a reduced set of habitat variables that describe most of the variability among the sampled sites. The habitat characteristics sampled within the five study units were compared statistically. Bivariate correlations between riparian habitat variables and either nutrient-chemistry or biological-response variables were examined for all sites combined, and for sites within each study area. Nutrient concentrations were correlated with the extent of riparian cropland. For nitrogen species, these correlations were more frequently at the basin scale, whereas for phosphorus, they were about equally frequent at the segment and basin scales. Basin-level extents of riparian cropland and reach-level bank vegetative cover were correlated strongly with both total nitrogen and dissolved inorganic nitrogen (DIN) among multiple study areas, reflecting the importance of agricultural land-management and conservation practices for reducing nitrogen delivery from near-stream sources. When sites lacking segment-level wetlands were excluded, the negative correlation of riparian wetland extent with DIN among 49 sites was strong at the reach and segment levels. Riparian wetland vegetation thus may be removing dissolved nutrients from soil water and shallow groundwater passing through riparian zones. Other habitat variables that correlated strongly with nitrogen and phosphorus species included suspended sediment, light availability, and antecedent water temperature. Chlorophyll concentrations in seston were positively correlated with phosphorus concentrations for all sites combined. Benthic chlorophyll was correlated strongly with nutrient concentrations in only the Delmarva study area and only in fine-grained habitats. Current velocity or hydraulic scour could explain correlation patterns for benthic chlorophyll among Georgia sites, whereas chlorophyll in seston was correlated with antecedent water temperature among Washington and Delmarva sites. The lack of any consistent correlation pattern between habitat characteristics and organic material density (ash-free dry mass)

Elusive or Illuminating: Using the Web To Explore the Salem Witchcraft Trials.

ERIC Educational Resources Information Center

Hurter, Stephanie R.

2003-01-01

Presents Web sites useful for teaching about the Salem (Massachusetts) witchcraft trials. Includes Web sites that offer primary source material, collections of Web sites, teaching material, and sites that are interactive, including features, such as QuickTime movies. (CMK)

The fate of prospective spine studies registered on www.ClinicalTrials.gov.

PubMed

Ohnmeiss, Donna D

2015-03-01

There has been concern expressed about research ethics with respect to not fully reporting data collected during clinical studies. One site available for all clinical trials is ClinicalTrials.gov. The original purpose of this site was to facilitate patients seeking a trial for the treatment of their particular condition. The internationally available site offers general information about the study, sponsor name, principal investigator, patient selection criteria, enrollment goal, study design, outcome measures, participating centers, initiation date, date posted, date completed, and other pertinent data. The site can be used to identify studies conducted for a particular condition or intervention. The purpose of this study was to investigate the fate of spine-related studies registered on www.ClinicalTrials.gov, with particular focus on the publication rate of completed trials. Analysis and classification of clinical studies posted on an international research registry Web page and literature search for related publications. Not applicable. The primary outcome measure was publication of the study registered on ClinicalTrials.gov. Multiple searches were conducted on ClinicalTrials.gov Web site to identify studies related to commonly treated spinal conditions, including herniated disc, degenerative disc disease, stenosis, and spondylolisthesis. Studies related to tumors, fractures, or that included nonspine conditions were not included. For studies classified as completed more than 18 months before this review, literature searches were conducted to determine if the results of the study had been published and factors related to publication. The author has no financial conflict related to this work. There were 263 spine-related studies identified from searches on the ClinicalTrials.gov site. Data on the site had the studies classified as follows: 72 completed, 70 active, not recruiting (generally indicates collecting follow-up data), 74 recruiting, 11 recruiting by invitation, 13 not yet recruiting, 18 terminated, 4 withdrawn, and 1 suspended. Among the 72 studies indicated to be completed, 28 (38.9%) have been published. The mean time to publish was 27.9 months from the date of completion. Among unpublished studies, the mean length of time from study completion to the preparation of this article was 62.0 months. There was no difference in the likelihood of publication based on the geographic region of study origin or whether the study was registered before or after initiation. There were statistically significant relationships between the publication rate and the funding type as well as the research type (p<.05) with industrial-funded studies and those evaluating devices having a lower publication rate and those that were funded by a federal agency and comparing surgery to nonoperative care had the highest publication rates. Although the 38.9% publication rate for spine-related studies found in this study appears low, it is in line with other studies reporting a 22.8% publication rate for arthroplasty trials and 43.2% for orthopedic trauma trials. In addition to ClinicalTrials.gov Web site fulfilling its original goal of providing patients information about clinical studies, it can also provide a means of tracking publication of prospective studies, changes to protocols, matching publication content to posted study design, and others and raise queries concerning the reasons for not publishing what appear to be well-designed studies. The posting of spine studies before initiation can increase transparency and ability to evaluate clinical trials in spine. Copyright © 2015 Elsevier Inc. All rights reserved.

Estimation of ultrafine particle concentrations at near-highway residences using data from local and central monitors

PubMed Central

Fuller, Christina H.; Brugge, Doug; Williams, Paige; Mittleman, Murray; Durant, John L.; Spengler, John D.

2012-01-01

Ultrafine particles (UFP; aerodynamic diameter < 0.1 micrometers) are a ubiquitous exposure in the urban environment and are elevated near highways. Most epidemiological studies of UFP health effects use central site monitoring data, which may misclassify exposure. Our aims were to: (1) examine the relationship between distant and proximate monitoring sites and their ability to predict hourly UFP concentration measured at residences in an urban community with a major interstate highway and; (2) determine if meteorology and proximity to traffic improve explanatory power. Short-term (1 – 3 weeks) residential monitoring of UFP concentration was conducted at 18 homes. Long-term monitoring was conducted at two near-highway monitoring sites and a central site. We created models of outdoor residential UFP concentration based on concentrations at the near-highway site, at the central site, at both sites together and without fixed sites. UFP concentration at residential sites was more highly correlated with those at a near-highway site than a central site. In regression models of each site alone, a 10% increase in UFP concentration at a near-highway site was associated with a 6% (95% CI: 6%, 7%) increase at residences while a 10% increase in UFP concentration at the central site was associated with a 3% (95% CI: 2%, 3%) increase at residences. A model including both sites showed minimal change in the magnitude of the association between the near-highway site and the residences, but the estimated association with UFP concentration at the central site was substantially attenuated. These associations remained after adjustment for other significant predictors of residential UFP concentration, including distance from highway, wind speed, wind direction, highway traffic volume and precipitation. The use of a central site as an estimate of personal exposure for populations near local emissions of traffic-related air pollutants may result in exposure misclassification. PMID:23645993

Estimation of ultrafine particle concentrations at near-highway residences using data from local and central monitors.

PubMed

Fuller, Christina H; Brugge, Doug; Williams, Paige; Mittleman, Murray; Durant, John L; Spengler, John D

2012-09-01

Ultrafine particles (UFP; aerodynamic diameter < 0.1 micrometers) are a ubiquitous exposure in the urban environment and are elevated near highways. Most epidemiological studies of UFP health effects use central site monitoring data, which may misclassify exposure. Our aims were to: (1) examine the relationship between distant and proximate monitoring sites and their ability to predict hourly UFP concentration measured at residences in an urban community with a major interstate highway and; (2) determine if meteorology and proximity to traffic improve explanatory power. Short-term (1 - 3 weeks) residential monitoring of UFP concentration was conducted at 18 homes. Long-term monitoring was conducted at two near-highway monitoring sites and a central site. We created models of outdoor residential UFP concentration based on concentrations at the near-highway site, at the central site, at both sites together and without fixed sites. UFP concentration at residential sites was more highly correlated with those at a near-highway site than a central site. In regression models of each site alone, a 10% increase in UFP concentration at a near-highway site was associated with a 6% (95% CI: 6%, 7%) increase at residences while a 10% increase in UFP concentration at the central site was associated with a 3% (95% CI: 2%, 3%) increase at residences. A model including both sites showed minimal change in the magnitude of the association between the near-highway site and the residences, but the estimated association with UFP concentration at the central site was substantially attenuated. These associations remained after adjustment for other significant predictors of residential UFP concentration, including distance from highway, wind speed, wind direction, highway traffic volume and precipitation. The use of a central site as an estimate of personal exposure for populations near local emissions of traffic-related air pollutants may result in exposure misclassification.

GREAT I Study of the Upper Mississippi River. Technical Appendixes. Volume 2. Floodplain Management, Dredged Material Uses, Dredging Requirements.

DTIC Science & Technology

1980-09-01

placement of dredged material is proposed, a quantitative analysis of the effects on the 1-percent chance flood be made. The analysis must include a...FPMWG will accept the site. b. Until a quantitative analysis is conducted, place- ment sites be selected following these guidelines. (1) Dredge4 material... Analysis of site-specific encroachments would continue to be made without considering the opposite bank impacts or the long-term cumulative effects. 5

Environmental Impact Study of the Elm Fork Region of the Trinity River.

DTIC Science & Technology

1972-04-14

uninterruptedly for two to four years would be re- quired. Especially in the latter two realms it is essential to compare annual data for several years in order to...site (Crook, 1952; Crook and Harris, 1953) located in the northeastern part of the sur- veyed area. The Wheeler site essentially has been destroyed...quarrying of raw mate- rial including quartzite and chert. These sites may be of any age for these resources were continually used. 18 oil 031 12 ELM FORK

Remedial investigation/feasibility study for the David Witherspoon, Inc., 901 Site, Knoxville, Tennessee: Volume 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-10-01

This remedial investigation (RI)/feasibility study (FS) supports the selection of remedial actions for the David Witherspoon, Inc. 901 Maryville Pike Site in Knoxville, Tennessee. Operations at the site, used as a recycling center, have resulted in past, present, and potential future releases of hazardous substances in to the environment. This Site is a Tennessee Superfund site. A phased approach was planned to (1) gather existing data from previous investigations managed by the Tenn. Dept. of Environment and Conservation; (2) perform a preliminary RI, including risk assessments, and an FS with existing data to identify areas where remedial action may bemore » necessary; (3) gather additional field data to adequately define the nature and extent of risk-based contaminants that present identifiable threats to human and/or ecological receptors; and (4) develop remedial action alternatives to reduce risks to acceptable levels.« less

Letter Report: Yucca Mountain Environmental Monitoring Systems Initiative - Air Quality Scoping Study for Caliente, Lincoln County, Nevada

DOE Office of Scientific and Technical Information (OSTI.GOV)

J. Englebrecht; I. Kavouras; D. Campbell

2008-08-01

The Desert Research Institute (DRI) is performing a scoping study as part of the U.S. Department of Energy's Yucca Mountain Environmental Monitoring Systems Initiative (EMSI). The main objective is to obtain baseline air quality information for Yucca Mountain and an area surrounding the Nevada Test Site (NTS). Air quality and meteorological monitoring and sampling equipment housed in a mobile trailer (shelter) is collecting data at eight sites outside the NTS, including Ash Meadows National Wildlife Refuge (NWR), Beatty, Sarcobatus Flats, Rachel, Caliente, Pahranagat NWR, Crater Flat, and Tonopah Airport, and at four sites on the NTS (Engelbrecht et al., 2007a-d).more » The trailer is stationed at any one site for approximately eight weeks at a time. This letter report provides a summary of air quality and meteorological data, on completion of the site's sampling program.« less

Letter Report: Yucca Mountain Environmental Monitoring Systems Initiative - Air Quality Scoping Study for Pahranagat National Wildlife Refuge, Lincoln County, Nevada

DOE Office of Scientific and Technical Information (OSTI.GOV)

J. Englebrecht; I. Kavouras; D. Campbell

2008-08-01

The Desert Research Institute (DRI) is performing a scoping study as part of the U.S. Department of Energy's Yucca Mountain Environmental Monitoring Systems Initiative (EMSI). The main objective is to obtain baseline air quality information for Yucca Mountain and an area surrounding the Nevada Test Site (NTS). Air quality and meteorological monitoring and sampling equipment housed in a mobile trailer (shelter) is collecting data at eight sites outside the NTS, including Ash Meadows National Wildlife Refuge (NWR), Pahranagat NWR, Beatty, Rachel, Caliente, Crater Flat, and Tonopah Airport, and at four sites on the NTS (Engelbrecht et al., 2007a-d). The trailermore » is stationed at any one site for approximately eight weeks at a time. This letter report provides a summary of air quality and meteorological data on completion of the site's sampling program.« less

Letter Report Yucca Mountain Environmental Monitoring Systems Initiative - Air Quality Scoping Study for Pahranagat National Wildlife Refuge, Lincoln County, Nevada

DOE Office of Scientific and Technical Information (OSTI.GOV)

J. Engelbrecht; I. Kavouras; D. Campbell

2009-04-02

The Desert Research Institute (DRI) is performing a scoping study as part of the U.S. Department of Energy's Yucca Mountain Environmental Monitoring Systems Initiative (EMSI). The main objective is to obtain baseline air quality information for Yucca Mountain and an area surrounding the Nevada Test Site (NTS). Air quality and meteorological monitoring and sampling equipment housed in a mobile trailer (shelter) is collecting data at eight sites outside the NTS, including Ash Meadows National Wildlife Refuge (NWR), Pahranagat NWR, Beatty, Rachel, Caliente, Crater Flat, and Tonopah Airport, and at four sites on the NTS (Engelbrecht et al., 2007a-d). The trailermore » is stationed at any one site for approximately eight weeks at a time. This letter report provides a summary of air quality and meteorological data on completion of the site's sampling program.« less

DOE/NV/26383-LTR2008-01 Letter Report Yucca Mountain Environmental Monitoring Systems Initiative - Air Quality Scoping Study for Caliente, Lincoln County, Nevada

DOE Office of Scientific and Technical Information (OSTI.GOV)

J. Engelbrecht; I. Kavouras; D. Campbell

2009-04-02

The Desert Research Institute (DRI) is performing a scoping study as part of the U.S. Department of Energy's Yucca Mountain Environmental Monitoring Systems Initiative (EMSI). The main objective is to obtain baseline air quality information for Yucca Mountain and an area surrounding the Nevada Test Site (NTS). Air quality and meteorological monitoring and sampling equipment housed in a mobile trailer (shelter) is collecting data at eight sites outside the NTS, including Ash Meadows National Wildlife Refuge (NWR), Beatty, Sarcobatus Flats, Rachel, Caliente, Pahranagat NWR, Crater Flat, and Tonopah Airport, and at four sites on the NTS (Engelbrecht et al., 2007a-d).more » The trailer is stationed at any one site for approximately eight weeks at a time. This letter report provides a summary of air quality and meteorological data, on completion of the site's sampling program.« less

Managing the risks of on-site health centers.

PubMed

Gorman, Kathleen M; Miller, Ross M

2011-11-01

This review sought to assess compliance concerns, determine risk management strategies, and identify opportunities for future research to contribute to employers' understanding of the laws and regulations that apply to on-site care. A comprehensive review of databases, professional organizations' websites, and journals resulted in 22 publications reporting on the consequences of noncompliance among on-site health centers accepted for inclusion. None of those studies reported a study design or quantifiable outcome data. Two noncompliance themes were repeated among the publications. First, direct penalties included fines, civil actions, loss of licensure, and, potentially, criminal charges. Second, noncompliance also resulted in indirect costs such as employee mistrust and lowered standards of care, which jeopardize on-site health centers' ability to demonstrate a return on investment. Further research with rigorous methodology is needed to inform employer decisions about on-site health services and associated risk management. Copyright 2011, SLACK Incorporated.

Uncovering Global SUMOylation Signaling Networks in a Site-Specific Manner

PubMed Central

Hendriks, Ivo A.; D’Souza, Rochelle C.J.; Yang, Bing; Verlaan-de Vries, Matty; Mann, Matthias; Vertegaal, Alfred C.O.

2014-01-01

SUMOylation is a reversible post-translational modification essential for genome stability. Using high-resolution mass spectrometry, we have studied global SUMOylation in human cells and in a site-specific manner, identifying a total of over 4,300 SUMOylation sites in over 1,600 proteins. Moreover, for the first time in excess of 1,000 SUMOylation sites were identified under standard growth conditions. SUMOylation dynamics were quantitatively studied in response to SUMO protease inhibition, proteasome inhibition and heat shock. A considerable amount of SUMOylated lysines have previously been reported to be ubiquitylated, acetylated or methylated, indicating crosstalk between SUMO and other post-translational modifications. We identified 70 phosphorylation and 4 acetylation events in close proximity to SUMOylation sites, and provide evidence for acetylation-dependent SUMOylation of endogenous histone H3. SUMOylation regulates target proteins involved in all nuclear processes including transcription, DNA repair, chromatin remodeling, pre-mRNA splicing and ribosome assembly. PMID:25218447

Letter Report Yucca Mountain Environmental Monitoring Systems Initiative - Air Quality Scoping Study for Tonopah Airport, Nye County, Nevada

DOE Office of Scientific and Technical Information (OSTI.GOV)

J. Engelbrecht; I. Kavouras; D. Campbell

2009-04-02

The Desert Research Institute (DRI) is performing a scoping study as part of the U.S. Department of Energy's Yucca Mountain Environmental Monitoring Systems Initiative (EMSI). The main objective is to obtain baseline air quality information for Yucca Mountain and an area surrounding the Nevada Test Site (NTS). Air quality and meteorological monitoring and sampling equipment housed in a mobile trailer (shelter) is collecting data at eight sites outside the NTS, including Ash Meadows National Wildlife Refuge (NWR), Tonopah Airport, Beatty, Rachel, Caliente, Pahranagat NWR, Crater Flat, and the Tonopah Airport, and at four sites on the NTS (Engelbrecht et al.,more » 2007a-d). The trailer is stationed at any one site for approximately eight weeks at a time. This letter report provides a summary of air quality and meteorological data, on completion of the site's sampling program.« less

Letter Report: Yucca Mountain Environmental Monitoring Systems Initiative - Air Quality Scoping Study for Tonopah Airport, Nye County, Nevada

DOE Office of Scientific and Technical Information (OSTI.GOV)

J. Engelbrecht; I. Kavouras; D Campbell

2008-08-01

The Desert Research Institute (DRI) is performing a scoping study as part of the U.S. Department of Energy's Yucca Mountain Environmental Monitoring Systems Initiative (EMSI). The main objective is to obtain baseline air quality information for Yucca Mountain and an area surrounding the Nevada Test Site (NTS). Air quality and meteorological monitoring and sampling equipment housed in a mobile trailer (shelter) is collecting data at eight sites outside the NTS, including Ash Meadows National Wildlife Refuge (NWR), Tonopah Airport, Beatty, Rachel, Caliente, Pahranagat NWR, Crater Flat, and the Tonopah Airport, and at four sites on the NTS (Engelbrecht et al.,more » 2007a-d). The trailer is stationed at any one site for approximately eight weeks at a time. This letter report provides a summary of air quality and meteorological data, on completion of the site's sampling program.« less

Methods for using clinical laboratory test results as baseline confounders in multi-site observational database studies when missing data are expected.

PubMed

Raebel, Marsha A; Shetterly, Susan; Lu, Christine Y; Flory, James; Gagne, Joshua J; Harrell, Frank E; Haynes, Kevin; Herrinton, Lisa J; Patorno, Elisabetta; Popovic, Jennifer; Selvan, Mano; Shoaibi, Azadeh; Wang, Xingmei; Roy, Jason

2016-07-01

Our purpose was to quantify missing baseline laboratory results, assess predictors of missingness, and examine performance of missing data methods. Using the Mini-Sentinel Distributed Database from three sites, we selected three exposure-outcome scenarios with laboratory results as baseline confounders. We compared hazard ratios (HRs) or risk differences (RDs) and 95% confidence intervals (CIs) from models that omitted laboratory results, included only available results (complete cases), and included results after applying missing data methods (multiple imputation [MI] regression, MI predictive mean matching [PMM] indicator). Scenario 1 considered glucose among second-generation antipsychotic users and diabetes. Across sites, glucose was available for 27.7-58.9%. Results differed between complete case and missing data models (e.g., olanzapine: HR 0.92 [CI 0.73, 1.12] vs 1.02 [0.90, 1.16]). Across-site models employing different MI approaches provided similar HR and CI; site-specific models provided differing estimates. Scenario 2 evaluated creatinine among individuals starting high versus low dose lisinopril and hyperkalemia. Creatinine availability: 44.5-79.0%. Results differed between complete case and missing data models (e.g., HR 0.84 [CI 0.77, 0.92] vs. 0.88 [0.83, 0.94]). HR and CI were identical across MI methods. Scenario 3 examined international normalized ratio (INR) among warfarin users starting interacting versus noninteracting antimicrobials and bleeding. INR availability: 20.0-92.9%. Results differed between ignoring INR versus including INR using missing data methods (e.g., RD 0.05 [CI -0.03, 0.13] vs 0.09 [0.00, 0.18]). Indicator and PMM methods gave similar estimates. Multi-site studies must consider site variability in missing data. Different missing data methods performed similarly. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

Computational Tools for Allosteric Drug Discovery: Site Identification and Focus Library Design.

PubMed

Huang, Wenkang; Nussinov, Ruth; Zhang, Jian

2017-01-01

Allostery is an intrinsic phenomenon of biological macromolecules involving regulation and/or signal transduction induced by a ligand binding to an allosteric site distinct from a molecule's active site. Allosteric drugs are currently receiving increased attention in drug discovery because drugs that target allosteric sites can provide important advantages over the corresponding orthosteric drugs including specific subtype selectivity within receptor families. Consequently, targeting allosteric sites, instead of orthosteric sites, can reduce drug-related side effects and toxicity. On the down side, allosteric drug discovery can be more challenging than traditional orthosteric drug discovery due to difficulties associated with determining the locations of allosteric sites and designing drugs based on these sites and the need for the allosteric effects to propagate through the structure, reach the ligand binding site and elicit a conformational change. In this study, we present computational tools ranging from the identification of potential allosteric sites to the design of "allosteric-like" modulator libraries. These tools may be particularly useful for allosteric drug discovery.

Assessing Non-Technical Site Suitability Criteria for Stormwater Capture, Treatment and Recharge

NASA Astrophysics Data System (ADS)

Eisenstein, W.

2016-12-01

This presentation will describe a new method for assessing non-technical site suitability criteria for the siting of stormwater capture, treatment and recharge (or stormwater CTR) facilities in Sonoma County, California, USA. "Non-technical site suitability criteria" include issues such as community acceptance, aesthetics, nuisances and hazards, and compatibility with neighboring land uses, and are distinguished from "technical criteria" such as hydrology and soil characteristics that are the traditional subject of suitability analyses. Non-technical criteria are rarely, if ever, considered in formal siting suitability studies conducted by agencies and municipalities, yet can be fatal to the prospects of a given project's construction if not identified and mitigated. The researchers developed a new method for identifying and spatially characterizing relevant non-technical criteria through interviews and questionnaires with community stakeholders, and introducing those criteria into a spatial multi-criteria decision analysis framework that assesses site suitabilty across a study watershed (the Upper Petaluma River watershed in Sonoma County).

Petersburg National Battlefield : alternative transportation feasibility study

DOT National Transportation Integrated Search

2012-11-13

This report studies the feasibility of alternative solutions to several transportation problems affecting Petersburg National Battlefield in Petersburg, Virginia. Current transportation problems include site-specific access issues, wayfinding and nav...

An Examination of Library World Wide Web Sites at Medium-Sized Universities.

ERIC Educational Resources Information Center

Tolppanen, Bradley P.; Miller, Joan; Wooden, Martha H.

2000-01-01

Presents the results of a study of Web sites for 133 academic libraries serving medium-sized universities. Suggests that navigational and design aspects need improvement; information should not be included unless it will be accessed and used; and greater use should be made of online tutorials and virtual tours to supplement regular bibliographic…

Lexicogrammar in the International Construction Industry: A Corpus-Based Case Study of Japanese-Hong-Kongese On-Site Interactions in English

ERIC Educational Resources Information Center

Handford, Michael; Matous, Petr

2011-01-01

The purpose of this research is to identify and interpret statistically significant lexicogrammatical items that are used in on-site spoken communication in the international construction industry, initially through comparisons with reference corpora of everyday spoken and business language. Several data sources, including audio and video…

The effects of festival attributes upon perceptions of crowding

Treesearch

Matthew Anderson; Deborah Kerstette; Alan Graefe

1998-01-01

The primary purpose of this study was to explore the relationship between festival attributes and perceived crowding at a festival site. Visitors to the Northwest Folklife Festival in Seattle, Washington, were chosen by a systematic sampling method to complete an on-site and follow-up survey. These surveys included questions which addressed the determinate attributes...

The Use of Coastal Brownfields as Nature Preserves

ERIC Educational Resources Information Center

Levi, Daniel; Kocher, Sara

2006-01-01

Brownfields have the potential to be reused as nature preserves or recreation areas. This reuse depends on the public's perceptions of risk and their willingness to support the new uses of the sites. This study examines attitudes about the reuse of large coastal brownfields from local and nonlocal students and the public. The sites include the…

Tech Talk for Social Studies Teachers Lest We Forget: Remembering Pearl Harbor.

ERIC Educational Resources Information Center

Green, Tim

2001-01-01

Presents an annotated bibliography that provides Web sites about Pearl Harbor (Hawaii). Includes Web sites that cover Pearl Harbor history, a live view of Pearl Harbor, stories from people who remember where they were during the attack, information on the naval station at Pearl Harbor, and a virtual tour of the USS Arizona. (CMK)

High Plains Regional Ground-water Study web site

USGS Publications Warehouse

Qi, Sharon L.

2000-01-01

Now available on the Internet is a web site for the U.S. Geological Survey's (USGS) National Water-Quality Assessment (NAWQA) Program-High Plains Regional Ground-Water Study. The purpose of the web site is to provide public access to a wide variety of information on the USGS investigation of the ground-water resources within the High Plains aquifer system. Typical pages on the web site include the following: descriptions of the High Plains NAWQA, the National NAWQA Program, the study-area setting, current and past activities, significant findings, chemical and ancillary data (which can be downloaded), listing and access to publications, links to other sites about the High Plains area, and links to other web sites studying High Plains ground-water resources. The High Plains aquifer is a regional aquifer system that underlies 174,000 square miles in parts of eight States (Colorado, Kansas, Nebraska, New Mexico, Oklahoma, South Dakota, Texas, and Wyoming). Because the study area is so large, the Internet is an ideal way to provide project data and information on a near real-time basis. The web site will be a collection of living documents where project data and information are updated as it becomes available throughout the life of the project. If you have an interest in the High Plains area, you can check this site periodically to learn how the High Plains NAWQA activities are progressing over time and access new data and publications as they become available.

78 FR 8586 - PEPSICO, Inc., Business & Information Solutions (BIS) Division Including On-Site Leased Workers...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-06

...., Business & Information Solutions (BIS) Division, including on-site leased workers of Cognizant Technology..., Inc., Business & Information Solutions (BIS) Division Including On-Site Leased Workers From Procurestaff, Cognizant, Infosys, Wipro, and TCS; Plano, TX; PEPSICO, Inc., Business & Information Solutions...

77 FR 21588 - Hart and Cooley, Inc., A Subsidiary of Tomkins, PLC Including On-Site Leased Workers from...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-10

... Subsidiary of Tomkins, PLC Including On- Site Leased Workers from Reliable, Masiello Employment Services..., applicable to workers of Hart and Cooley, Inc., a subsidiary of Tomkins, PLC, including on-site leased... issued as follows: ``All workers from Hart and Cooley, Inc., a subsidiary of Tomkins, PLC, including on...

Tampa Bay Study Data and Information Management System (DIMS)

NASA Astrophysics Data System (ADS)

Edgar, N. T.; Johnston, J. B.; Yates, K.; Smith, K. E.

2005-05-01

Providing easy access to data and information is an essential component of both science and management. The Tampa Bay Data and Information Management System (DIMS) catalogs and publicizes data and products which are generated through the Tampa Bay Integrated Science Study. The publicly accessible interface consists of a Web site (http://gulfsci.usgs.gov), a digital library, and an interactive map server (IMS). The Tampa Bay Study Web site contains information from scientists involved in the study, and is also the portal site for the digital library and IMS. Study information is highlighted on the Web site according to the estuarine component: geology and geomorphology, water and sediment quality, ecosystem structure and function, and hydrodynamics. The Tampa Bay Digital Library is a web-based clearinghouse for digital products on Tampa Bay, including documents, maps, spatial and tabular data sets, presentations, etc. New developments to the digital library include new search features, 150 new products over the past year, and partnerships to expand the offering of science products. The IMS is a Web-based geographic information system (GIS) used to store, analyze and display data pertaining to Tampa Bay. Upgrades to the IMS have improved performance and speed, as well as increased the number of data sets available for mapping. The Tampa Bay DIMS is a dynamic entity and will continue to evolve with the study. Beginning in 2005, the Tampa Bay Integrated Coastal Model will have a more prominent presence within the DIMS. The Web site will feature model projects and plans; the digital library will host model products and data sets; the IMS will display spatial model data sets and analyses. These tools will be used to increase communication of USGS efforts in Tampa Bay to the public, local managers, and scientists.

[Effect of compliance with an antibiotic prophylaxis protocol in surgical site infections in appendectomies. Prospective cohort study].

PubMed

Sánchez-Santana, Tomás; Del-Moral-Luque, Juan Antonio; Gil-Yonte, Pablo; Bañuelos-Andrío, Luis; Durán-Poveda, Manuel; Rodríguez-Caravaca, Gil

Antibiotic prophylaxis is the most suitable tool for preventing surgical site infection. This study assessed compliance with antibiotic prophylaxis in surgery for acute appendicitis, and the effect of this compliance on surgical site infection. Prospective cohort study to evaluate compliance with antibiotic prophylaxis protocol in appendectomies. An assessment was made of the level of compliance with prophylaxis, as well as the causes of non-compliance. The incidence of surgical site infection was studied after a maximum incubation period of 30 days. The relative risk adjusted with a logistic regression model was used to assess the effect of non-compliance of prophylaxis on surgical site infection. The study included a total of 930 patients. Antibiotic prophylaxis was indicated in all patients, and administered in 71.3% of cases, with an overall protocol compliance of 86.1%. The principal cause of non-compliance was time of initiation. Cumulative incidence of surgical site infection was 4.6%. No relationship was found between inadequate prophylaxis compliance and infection (relative risk=0.5; 95% CI: 0.1-1.9) (P>.05). Compliance of antibiotic prophylaxis was high, but could be improved. No relationship was found between prophylaxis compliance and surgical site infection rate. Copyright © 2016 Academia Mexicana de Cirugía A.C. Publicado por Masson Doyma México S.A. All rights reserved.

Pilgrims, Pumpkins, and Turkeys: A Thanksgiving Bounty!!!

ERIC Educational Resources Information Center

Byerly, Greg; Brodie, Carolyn S.

1999-01-01

Describes several Thanksgiving Web sites, including those with historical information, favorite Thanksgiving foods and recipes, songs and games, arts and crafts activities, and some sites "just for fun." Sites include everything from the Macy's Day Parade site, to PlimothonWeb, to Thanksgiving clip art. (AEF)

Superfund Record of Decision (EPA Region 6): Koppers Texarkana Site, Texarkana, Texas (first remedial action), September 1988

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The Koppers Texarkana site is located within the City of Texarkana, Texas. The site consists of a 34-acre residential area and a 28-acre former sand and gravel operation. The Koppers Company operated the site as a wood-preserving facility from 1910 to 1961 using pentachlorophenol (PCP), creosote, and metallic salts in the operation. The site is currently owned by Carver Terrace, Inc. The Texas Department of Water Resources became aware of the site in 1979 through the Ekhardt Survey. The remedial investigation indicated that the highest concentration of site contaminants in the soil were located near the operations and drip trackmore » areas of the old wood-preserving facility. The primary contaminants of concern affecting the soil, ground water, and sediments are volatile organic compounds including benzene, xylenes, and toluene, other organics including polynuclear aromatic hydrocarbons and PCP, and metals including arsenic. The selected remedial action for the site is included.« less

Organisation and features of hospital, intermediate care and social services in English sites with low rates of delayed discharge.

PubMed

Baumann, Matt; Evans, Sherrill; Perkins, Margaret; Curtis, Lesley; Netten, Ann; Fernandez, Jose-Luis; Huxley, Peter

2007-07-01

In recent years, there has been significant concern, and policy activity, in relation to the problem of delayed discharges from hospital. Key elements of policy to tackle delays include new investment, the establishment of the Health and Social Care Change Agent Team, and the implementation of the Community Care (Delayed Discharge) Act 2003. Whilst the problem of delays has been widespread, some authorities have managed to tackle delays successfully. The aim of the qualitative study reported here was to investigate discharge practice and the organisation of services at sites with consistently low rates of delay, in order to identify factors supporting such good performance. Six 'high performing' English sites (each including a hospital trust, a local authority, and a primary care trust) were identified using a statistical model, and 42 interviews were undertaken with health and social services staff involved in discharge arrangements. Additionally, the authors set out to investigate the experiences of patients in the sites to examine whether there was a cost to patient care and outcomes of discharge arrangements in these sites, but unfortunately, it was not possible to secure sufficient patient participation. Whilst acknowledging the lack of patient experience and outcome data, a range of service elements was identified at the sites that contribute to the avoidance of delays, either through supporting efficiency within individual agencies or enabling more efficient joint working. Sites still struggling with delays should benefit from knowledge of this range. The government's reimbursement scheme appears to have been largely helpful in the study sites, prompting efficiency-driven changes to the organisation of services and discharge systems, but further focused research is required to provide clear evidence of its impact nationally, and in particular, how it impacts on staff, and patients and their families.

Associations of cumulative sun exposure and phenotypic characteristics with histologic solar elastosis

PubMed Central

Thomas, Nancy E.; Kricker, Anne; From, Lynn; Busam, Klaus; Millikan, Robert C.; Ritchey, Mary E.; Armstrong, Bruce K.; Lee-Taylor, Julia; Marrett, Loraine D.; Anton-Culver, Hoda; Zanetti, Roberto; Rosso, Stefano; Gallagher, Richard P.; Dwyer, Terence; Goumas, Chris; Kanetsky, Peter A.; Begg, Colin B.; Orlow, Irene; Wilcox, Homer; Paine, Susan; Berwick, Marianne

2010-01-01

Background Solar elastosis adjacent to melanomas in histologic sections is regarded as an indicator of sun exposure although the associations of ultraviolet (UV) exposure and phenotype with solar elastosis are yet to be fully explored. Methods The study included 2,589 incident primary melanoma patients with assessment of histologic solar elastosis in the population-based Genes, Environment, and Melanoma study. Ambient erythemal UV (UVE) at places of residence and sun exposure hours, including body site-specific exposure, were collected. We examined the association of cumulative site-specific and non site-specific sun exposure hours and ambient UVE with solar elastosis in multivariable models adjusted for age, sex, center, pigmentary characteristics, nevi and, where relevant, body site. Results Solar elastosis was associated most strongly with site-specific UVE (OR for top exposure quartile, 5.20; 95% CI, 3.40-7.96; P for trend <0.001) and also with site-specific sun exposure (OR for top quartile, 5.12; 95% CI, 3.35-7.83; P for trend <0.001). Older age (OR at >70 years, 7.69; 95% CI, 5.14-11.52); P trend < 0.001) and having more than 10 back nevi (OR, 0.77; 95% CI, 0.61-0.97; P = 0.03) were independently associated with solar elastosis. Conclusion Solar elastosis had a strong association with higher site-specific UVE dose, older age and fewer nevi. Impact Solar elastosis could be a useful biomarker of lifetime site-specific UV. Future research is needed to explore whether age represents more than simple accumulation of sun exposure and the reason that people with more nevi may be less prone to solar elastosis. PMID:20802019

Associations of cumulative sun exposure and phenotypic characteristics with histologic solar elastosis.

PubMed

Thomas, Nancy E; Kricker, Anne; From, Lynn; Busam, Klaus; Millikan, Robert C; Ritchey, Mary E; Armstrong, Bruce K; Lee-Taylor, Julia; Marrett, Loraine D; Anton-Culver, Hoda; Zanetti, Roberto; Rosso, Stefano; Gallagher, Richard P; Dwyer, Terence; Goumas, Chris; Kanetsky, Peter A; Begg, Colin B; Orlow, Irene; Wilcox, Homer; Paine, Susan; Berwick, Marianne

2010-11-01

Solar elastosis adjacent to melanomas in histologic sections is regarded as an indicator of sun exposure, although the associations of UV exposure and phenotype with solar elastosis are yet to be fully explored. The study included 2,589 incident primary melanoma patients with assessment of histologic solar elastosis in the population-based Genes, Environment, and Melanoma study. Ambient erythemal UV (UVE) at places of residence and sun exposure hours, including body site-specific exposure, were collected. We examined the association of cumulative site-specific and non-site-specific sun exposure hours and ambient UVE with solar elastosis in multivariable models adjusted for age, sex, center, pigmentary characteristics, nevi, and, where relevant, body site. Solar elastosis was associated most strongly with site-specific UVE [odds ratio (OR) for top exposure quartile, 5.20; 95% confidence interval (95% CI), 3.40-7.96; P for trend <0.001] and also with site-specific sun exposure (OR for top quartile, 5.12; 95% CI, 3.35-7.83; P for trend <0.001). Older age (OR at >70 years, 7.69; 95% CI, 5.14-11.52; P for trend < 0.001) and having more than 10 back nevi (OR, 0.77; 95% CI, 0.61-0.97; P = 0.03) were independently associated with solar elastosis. Solar elastosis had a strong association with higher site-specific UVE dose, older age, and fewer nevi. Solar elastosis could be a useful biomarker of lifetime site-specific UV. Future research is needed to explore whether age represents more than simple accumulation of sun exposure and to determine why people with more nevi may be less prone to solar elastosis. ©2010 AACR.

Modelling study of soil C, N and pH response to air pollution and climate change using European LTER site observations.

PubMed

Holmberg, Maria; Aherne, Julian; Austnes, Kari; Beloica, Jelena; De Marco, Alessandra; Dirnböck, Thomas; Fornasier, Maria Francesca; Goergen, Klaus; Futter, Martyn; Lindroos, Antti-Jussi; Krám, Pavel; Neirynck, Johan; Nieminen, Tiina Maileena; Pecka, Tomasz; Posch, Maximilian; Pröll, Gisela; Rowe, Ed C; Scheuschner, Thomas; Schlutow, Angela; Valinia, Salar; Forsius, Martin

2018-05-31

Current climate warming is expected to continue in coming decades, whereas high N deposition may stabilize, in contrast to the clear decrease in S deposition. These pressures have distinctive regional patterns and their resulting impact on soil conditions is modified by local site characteristics. We have applied the VSD+ soil dynamic model to study impacts of deposition and climate change on soil properties, using MetHyd and GrowUp as pre-processors to provide input to VSD+. The single-layer soil model VSD+ accounts for processes of organic C and N turnover, as well as charge and mass balances of elements, cation exchange and base cation weathering. We calibrated VSD+ at 26 ecosystem study sites throughout Europe using observed conditions, and simulated key soil properties: soil solution pH (pH), soil base saturation (BS) and soil organic carbon and nitrogen ratio (C:N) under projected deposition of N and S, and climate warming until 2100. The sites are forested, located in the Mediterranean, forested alpine, Atlantic, continental and boreal regions. They represent the long-term ecological research (LTER) Europe network, including sites of the ICP Forests and ICP Integrated Monitoring (IM) programmes under the UNECE Convention on Long-range Transboundary Air Pollution (LRTAP), providing high quality long-term data on ecosystem response. Simulated future soil conditions improved under projected decrease in deposition and current climate conditions: higher pH, BS and C:N at 21, 16 and 12 of the sites, respectively. When climate change was included in the scenario analysis, the variability of the results increased. Climate warming resulted in higher simulated pH in most cases, and higher BS and C:N in roughly half of the cases. Especially the increase in C:N was more marked with climate warming. The study illustrates the value of LTER sites for applying models to predict soil responses to multiple environmental changes. Copyright © 2017 Elsevier B.V. All rights reserved.

Test-retest and between-site reliability in a multicenter fMRI study.

PubMed

Friedman, Lee; Stern, Hal; Brown, Gregory G; Mathalon, Daniel H; Turner, Jessica; Glover, Gary H; Gollub, Randy L; Lauriello, John; Lim, Kelvin O; Cannon, Tyrone; Greve, Douglas N; Bockholt, Henry Jeremy; Belger, Aysenil; Mueller, Bryon; Doty, Michael J; He, Jianchun; Wells, William; Smyth, Padhraic; Pieper, Steve; Kim, Seyoung; Kubicki, Marek; Vangel, Mark; Potkin, Steven G

2008-08-01

In the present report, estimates of test-retest and between-site reliability of fMRI assessments were produced in the context of a multicenter fMRI reliability study (FBIRN Phase 1, www.nbirn.net). Five subjects were scanned on 10 MRI scanners on two occasions. The fMRI task was a simple block design sensorimotor task. The impulse response functions to the stimulation block were derived using an FIR-deconvolution analysis with FMRISTAT. Six functionally-derived ROIs covering the visual, auditory and motor cortices, created from a prior analysis, were used. Two dependent variables were compared: percent signal change and contrast-to-noise-ratio. Reliability was assessed with intraclass correlation coefficients derived from a variance components analysis. Test-retest reliability was high, but initially, between-site reliability was low, indicating a strong contribution from site and site-by-subject variance. However, a number of factors that can markedly improve between-site reliability were uncovered, including increasing the size of the ROIs, adjusting for smoothness differences, and inclusion of additional runs. By employing multiple steps, between-site reliability for 3T scanners was increased by 123%. Dropping one site at a time and assessing reliability can be a useful method of assessing the sensitivity of the results to particular sites. These findings should provide guidance toothers on the best practices for future multicenter studies.

An epigenome-wide study of body mass index and DNA methylation in blood using participants from the Sister Study cohort.

PubMed

Wilson, L E; Harlid, S; Xu, Z; Sandler, D P; Taylor, J A

2017-01-01

The relationship between obesity and chronic disease risk is well-established; the underlying biological mechanisms driving this risk increase may include obesity-related epigenetic modifications. To explore this hypothesis, we conducted a genome-wide analysis of DNA methylation and body mass index (BMI) using data from a subset of women in the Sister Study. The Sister Study is a cohort of 50 884 US women who had a sister with breast cancer but were free of breast cancer themselves at enrollment. Study participants completed examinations which included measurements of height and weight, and provided blood samples. Blood DNA methylation data generated with the Illumina Infinium HumanMethylation27 BeadChip array covering 27,589 CpG sites was available for 871 women from a prior study of breast cancer and DNA methylation. To identify differentially methylated CpG sites associated with BMI, we analyzed this methylation data using robust linear regression with adjustment for age and case status. For those CpGs passing the false discovery rate significance level, we examined the association in a replication set comprised of a non-overlapping group of 187 women from the Sister Study who had DNA methylation data generated using the Infinium HumanMethylation450 BeadChip array. Analysis of this expanded 450 K array identified additional BMI-associated sites which were investigated with targeted pyrosequencing. Four CpG sites reached genome-wide significance (false discovery rate (FDR) q<0.05) in the discovery set and associations for all four were significant at strict Bonferroni correction in the replication set. An additional 23 sites passed FDR in the replication set and five were replicated by pyrosequencing in the discovery set. Several of the genes identified including ANGPT4, RORC, SOCS3, FSD2, XYLT1, ABCG1, STK39, ASB2 and CRHR2 have been linked to obesity and obesity-related chronic diseases. Our findings support the hypothesis that obesity-related epigenetic differences are detectable in blood and may be related to risk of chronic disease.

Prophylactic negative-pressure wound therapy after cesarean is associated with reduced risk of surgical site infection: a systematic review and meta-analysis.

PubMed

Yu, Lulu; Kronen, Ryan J; Simon, Laura E; Stoll, Carolyn R T; Colditz, Graham A; Tuuli, Methodius G

2018-02-01

The objective of the study was to assess the effect of prophylactic negative-pressure wound therapy on surgical site infections and other wound complications in women after cesarean delivery. We searched Ovid Medline, Embase, SCOPUS, Cochrane Database of Systematic Reviews, and ClinicalTrials.gov. We included randomized controlled trials and observational studies comparing prophylactic negative-pressure wound therapy with standard wound dressing for cesarean delivery. The primary outcome was surgical site infection after cesarean delivery. Secondary outcomes were composite wound complications, wound dehiscence, wound seroma, endometritis, and hospital readmission. Heterogeneity was assessed using Higgin's I 2 . Relative risks with 95% confidence intervals were calculated using random-effects models. Six randomized controlled trials and 3 cohort studies in high-risk mostly obese women met inclusion criteria and were included in the meta-analysis. Six were full-text articles, 2 published abstracts, and 1 report of trial results in ClinicalTrials.gov. Studies were also heterogeneous in the patients included and type of negative-pressure wound therapy device. The risk of surgical site infection was significantly lower with the use of prophylactic negative-pressure wound therapy compared with standard wound dressing (7 studies: pooled risk ratio, 0.45; 95% confidence interval, 0.31-0.66; adjusted risk ratio, -6.0%, 95% confidence interval, -10.0% to -3.0%; number needed to treat, 17, 95% confidence interval, 10-34). There was no evidence of significant statistical heterogeneity (I 2  = 9.9%) or publication bias (Egger P = .532). Of the secondary outcomes, only composite wound complications were significantly reduced in patients receiving prophylactic negative-pressure wound therapy compared with standard dressing (9 studies: pooled risk ratio, 0.68, 95% confidence interval, 0.49-0.94). Studies on the effectiveness of prophylactic negative-pressure wound therapy at cesarean delivery are heterogeneous but suggest a reduction in surgical site infection and overall wound complications. Larger definitive trials are needed to clarify the clinical utility of prophylactic negative-pressure wound therapy after cesarean delivery. Copyright © 2017 Elsevier Inc. All rights reserved.

POLYSITE - An interactive package for the selection and refinement of Landsat image training sites

NASA Technical Reports Server (NTRS)

Mack, Marilyn J. P.

1986-01-01

A versatile multifunction package, POLYSITE, developed for Goddard's Land Analysis System, is described which simplifies the process of interactively selecting and correcting the sites used to study Landsat TM and MSS images. Image switching between the zoomed and nonzoomed image, color and shape cursor change and location display, and bit plane erase or color change, are global functions which are active at all times. Local functions possibly include manipulation of intensive study areas, new site definition, mensuration, and new image copying. The program is illustrated with the example of a full TM maser scene of metropolitan Washington, DC.

Satellite communications systems and technology. Executive Summary

NASA Technical Reports Server (NTRS)

Edelson, Burton I.; Pelton, Joseph N.; Bostian, Charles W.; Brandon, William T.; Chan, Vincent W. S.; Hager, E. Paul; Helm, Neil R.; Jennings, Raymond D.; Kwan, Robert; Mahle, Christoph E.

1993-01-01

NASA and the National Science Foundation (NSF) commissioned a panel of US experts to study the international status of satellite communications systems and technology. The study covers emerging systems concepts, applications, services, and the attendant technologies. The panel members travelled to Europe, Japan, and Russia to gather information first-hand. They visited 17 sites in Europe, 20 sites in Japan, and four in Russia. These included major manufacturers, government organizations, service providers, and associated R&D facilities. The panel's report was reviewed by the sites visited, by the panel, and by representatives of US industry. The report details the information collected and compares it to US activities.

Conservation of the critically endangered eastern Australian population of the grey nurse shark (Carcharias taurus) through cross-jurisdictional management of a network of marine-protected areas.

PubMed

Lynch, Tim P; Harcourt, Robert; Edgar, Graham; Barrett, Neville

2013-12-01

Between 2001 and 2009, 26 marine-protected areas (MPA) were established on the east Australian seaboard, at least in part, to manage human interactions with a critically endangered population of grey nurse shark, Carcharias taurus. This network is spread across six MPA systems and includes all 19 sites outlined in the National Recovery Plan for C. taurus, though five sites remain open to some forms of fishing. The reserve network has complex cross-jurisdictional management, as the sharks occur in waters controlled by the Australian states of New South Wales (NSW) and Queensland, as well as by the Commonwealth (Federal) government. Jurisdiction is further complicated by fisheries and conservation departments both engaging in management activities within each state. This has resulted in protected area types that include IUCN category II equivalent zones in NSW, Queensland, and Commonwealth marine parks that either overlay or complement another large scaled network of protected sites called critical habitats. Across the network, seven and eight rule permutations for diving and fishing, respectively, are applied to this population of sharks. Besides sites identified by the recovery plan, additional sites have been protected as part of the general development of MPA networks. A case study at one of these sites, which historically was known to be occupied by C. taurus but had been abandoned, appears to shows re-establishment of an aggregation of juvenile and sub-adult sharks. Concurrent with the re-establishment of the aggregation, a local dive operator increased seasonal dive visitation rates at the site fourfold. As a precautionary measure, protection of abandoned sites, which includes nursery and gestating female habitats are options that may assist recovery of the east coast population of C. taurus.

Conservation of the Critically Endangered Eastern Australian Population of the Grey Nurse Shark ( Carcharias taurus) Through Cross-Jurisdictional Management of a Network of Marine-Protected Areas

NASA Astrophysics Data System (ADS)

Lynch, Tim P.; Harcourt, Robert; Edgar, Graham; Barrett, Neville

2013-12-01

Between 2001 and 2009, 26 marine-protected areas (MPA) were established on the east Australian seaboard, at least in part, to manage human interactions with a critically endangered population of grey nurse shark, Carcharias taurus. This network is spread across six MPA systems and includes all 19 sites outlined in the National Recovery Plan for C. taurus, though five sites remain open to some forms of fishing. The reserve network has complex cross-jurisdictional management, as the sharks occur in waters controlled by the Australian states of New South Wales (NSW) and Queensland, as well as by the Commonwealth (Federal) government. Jurisdiction is further complicated by fisheries and conservation departments both engaging in management activities within each state. This has resulted in protected area types that include IUCN category II equivalent zones in NSW, Queensland, and Commonwealth marine parks that either overlay or complement another large scaled network of protected sites called critical habitats. Across the network, seven and eight rule permutations for diving and fishing, respectively, are applied to this population of sharks. Besides sites identified by the recovery plan, additional sites have been protected as part of the general development of MPA networks. A case study at one of these sites, which historically was known to be occupied by C. taurus but had been abandoned, appears to shows re-establishment of an aggregation of juvenile and sub-adult sharks. Concurrent with the re-establishment of the aggregation, a local dive operator increased seasonal dive visitation rates at the site fourfold. As a precautionary measure, protection of abandoned sites, which includes nursery and gestating female habitats are options that may assist recovery of the east coast population of C. taurus.

Studies on the regulation of the human E1 subunit of the 2-oxoglutarate dehydrogenase complex, including the identification of a novel calcium-binding site.

PubMed

Armstrong, Craig T; Anderson, J L Ross; Denton, Richard M

2014-04-15

The regulation of the 2-oxoglutarate dehydrogenase complex is central to intramitochondrial energy metabolism. In the present study, the active full-length E1 subunit of the human complex has been expressed and shown to be regulated by Ca2+, adenine nucleotides and NADH, with NADH exerting a major influence on the K0.5 value for Ca2+. We investigated two potential Ca2+-binding sites on E1, which we term site 1 (D114ADLD) and site 2 (E139SDLD). Comparison of sequences from vertebrates with those from Ca2+-insensitive non-vertebrate complexes suggest that site 1 may be the more important. Consistent with this view, a mutated form of E1, D114A, shows a 6-fold decrease in sensitivity for Ca2+, whereas variant ∆site1 (in which the sequence of site 1 is replaced by A114AALA) exhibits an almost complete loss of Ca2+ activation. Variant ∆site2 (in which the sequence is replaced with A139SALA) shows no measurable change in Ca2+ sensitivity. We conclude that site 1, but not site 2, forms part of a regulatory Ca2+-binding site, which is distinct from other previously described Ca2+-binding sites.

A systematic review of patient inflammatory bowel disease information resources on the World Wide Web.

PubMed

Bernard, André; Langille, Morgan; Hughes, Stephanie; Rose, Caren; Leddin, Desmond; Veldhuyzen van Zanten, Sander

2007-09-01

The Internet is a widely used information resource for patients with inflammatory bowel disease, but there is variation in the quality of Web sites that have patient information regarding Crohn's disease and ulcerative colitis. The purpose of the current study is to systematically evaluate the quality of these Web sites. The top 50 Web sites appearing in Google using the terms "Crohn's disease" or "ulcerative colitis" were included in the study. Web sites were evaluated using a (a) Quality Evaluation Instrument (QEI) that awarded Web sites points (0-107) for specific information on various aspects of inflammatory bowel disease, (b) a five-point Global Quality Score (GQS), (c) two reading grade level scores, and (d) a six-point integrity score. Thirty-four Web sites met the inclusion criteria, 16 Web sites were excluded because they were portals or non-IBD oriented. The median QEI score was 57 with five Web sites scoring higher than 75 points. The median Global Quality Score was 2.0 with five Web sites achieving scores of 4 or 5. The average reading grade level score was 11.2. The median integrity score was 3.0. There is marked variation in the quality of the Web sites containing information on Crohn's disease and ulcerative colitis. Many Web sites suffered from poor quality but there were five high-scoring Web sites.

Effects of well spacing on geological storage site distribution costs and surface footprint.

PubMed

Eccles, Jordan; Pratson, Lincoln F; Chandel, Munish Kumar

2012-04-17

Geological storage studies thus far have not evaluated the scale and cost of the network of distribution pipelines that will be needed to move CO(2) from a central receiving point at a storage site to injection wells distributed about the site. Using possible injection rates for deep-saline sandstone aquifers, we estimate that the footprint of a sequestration site could range from <100 km(2) to >100,000 km(2), and that distribution costs could be <$0.10/tonne to >$10/tonne. Our findings are based on two models for determining well spacing: one which minimizes spacing in order to maximize use of the volumetric capacity of the reservoir, and a second that determines spacing to minimize subsurface pressure interference between injection wells. The interference model, which we believe more accurately reflects reservoir dynamics, produces wider well spacings and a counterintuitive relationship whereby total injection site footprint and thus distribution cost declines with decreasing permeability for a given reservoir thickness. This implies that volumetric capacity estimates should be reexamined to include well spacing constraints, since wells will need to be spaced further apart than void space calculations might suggest. We conclude that site-selection criteria should include thick, low-permeability reservoirs to minimize distribution costs and site footprint.

Mojo Hand, a TALEN design tool for genome editing applications.

PubMed

Neff, Kevin L; Argue, David P; Ma, Alvin C; Lee, Han B; Clark, Karl J; Ekker, Stephen C

2013-01-16

Recent studies of transcription activator-like (TAL) effector domains fused to nucleases (TALENs) demonstrate enormous potential for genome editing. Effective design of TALENs requires a combination of selecting appropriate genetic features, finding pairs of binding sites based on a consensus sequence, and, in some cases, identifying endogenous restriction sites for downstream molecular genetic applications. We present the web-based program Mojo Hand for designing TAL and TALEN constructs for genome editing applications (http://www.talendesign.org). We describe the algorithm and its implementation. The features of Mojo Hand include (1) automatic download of genomic data from the National Center for Biotechnology Information, (2) analysis of any DNA sequence to reveal pairs of binding sites based on a user-defined template, (3) selection of restriction-enzyme recognition sites in the spacer between the TAL monomer binding sites including options for the selection of restriction enzyme suppliers, and (4) output files designed for subsequent TALEN construction using the Golden Gate assembly method. Mojo Hand enables the rapid identification of TAL binding sites for use in TALEN design. The assembly of TALEN constructs, is also simplified by using the TAL-site prediction program in conjunction with a spreadsheet management aid of reagent concentrations and TALEN formulation. Mojo Hand enables scientists to more rapidly deploy TALENs for genome editing applications.

Operational Procedures for Collecting Water-Quality Samples at Monitoring Sites on Maple Creek Near Nickerson and the Platte River at Louisville, Eastern Nebraska

USGS Publications Warehouse

Johnson, Steven M.; Swanson, Robert B.

1994-01-01

Prototype stream-monitoring sites were operated during part of 1992 in the Central Nebraska Basins (CNBR) and three other study areas of the National Water-Quality Assessment (NAWQ) Program of the U.S. Geological Survey. Results from the prototype project provide information needed to operate a net- work of intensive fixed station stream-monitoring sites. This report evaluates operating procedures for two NAWQA prototype sites at Maple Creek near Nickerson and the Platte River at Louisville, eastern Nebraska. Each site was sampled intensively in the spring and late summer 1992, with less intensive sampling in midsummer. In addition, multiple samples were collected during two high- flow periods at the Maple Creek site--one early and the other late in the growing season. Water-samples analyses included determination of pesticides, nutrients, major ions, suspended sediment, and measurements of physical properties. Equipment and protocols for the water-quality sampling procedures were evaluated. Operation of the prototype stream- monitoring sites included development and comparison of onsite and laboratory sample-processing proce- dures. Onsite processing was labor intensive but allowed for immediate preservation of all sampled constituents. Laboratory processing required less field labor and decreased the risk of contamination, but allowed for no immediate preservation of the samples.

Effect of on-site wastewater disposal on quality of ground water and base flow: A pilot study in Chester County, Southeastern Pennsylvania, 2005

USGS Publications Warehouse

Senior, Lisa A.; Cinotto, Peter J.

2007-01-01

On-site wastewater disposal has the potential to introduce contaminants into ground water and subsequently, by ground-water discharge, to streams. A pilot study was conducted during 2005 by the U.S. Geological Survey in cooperation with the Chester County Health Department and the Chester County Water Resources Authority to determine if wastewater components, including inorganic constituents and selected organic wastewater compounds, such as detergents, considered to be emerging contaminants, were present in ground water and stream base flow in areas with on-site wastewater disposal. The study area was a small watershed (about 7.1 square miles) of mixed land use drained by Broad Run in central Chester County, Pa. The area is underlain by fractured metamorphic rocks that form aquifers recharged by precipitation. Surface- and ground-water sampling was done in areas with and without on-site wastewater disposal for comparison, including a relatively densely populated village with cesspools and septic systems, a residential area with septic systems, a residential area served by sewers, and agricultural land. Samples were collected in May-June and September 2005 from eight headwater stream sites under base-flow conditions and in June 2005 from eight wells and two springs. Samples were analyzed for major ions, nutrients, boron, bacteria, and a suite of organic wastewater compounds. Several emerging contaminant wastewater compounds, including detergent components, insect repellents, and flame retardants, were detected in base-flow and ground-water samples. Stream base-flow samples generally contained more compounds and higher concentrations of those compounds than did ground-water samples, and of the ground-water samples, samples from springs contained more compounds and higher concentrations than samples from wells. Concentrations of nitrate, chloride, and boron (inorganic constituents associated with wastewater) generally were all elevated in base-flow and ground-water samples in areas with relatively high densities of on-site wastewater disposal (septic systems or cesspools) compared to other areas sampled. Results of this pilot study should be considered preliminary because of limited data.

Evaluation of Norwegian cancer hospitals' Web sites and explorative survey among cancer patients on their use of the Internet

PubMed Central

2001-01-01

Background Hospital homepages should provide comprehensive information on the hospital's services, such as departments and treatments available, prices, waiting time, leisure facilities, and other information important for patients and their relatives. Norway, with its population of approximately 4.3 million, ranks among the top countries globally for its ability to absorb and use technology. It is unclear to what degree Norwegian hospitals and patients use the Internet for information about health services. Objectives This study was undertaken to evaluate the quality of the biggest Norwegian cancer hospitals' Web sites and to gather some preliminary data on patients' use of the Internet. Methods In January 2001, we analyzed Web sites of 5 of the 7 biggest Norwegian hospitals treating cancer patients using a scoring system. The scoring instrument was based on recommendations developed by the Norwegian Central Information Service for Web sites and reflects the scope and depth of service information offered on hospital Web pages. In addition, 31 cancer patients visiting one hospital-based medical oncologist were surveyed about their use of the Internet. Results Of the 7 hospitals, 5 had a Web site. The Web sites differed markedly in quality. Types of information included - and number of Web sites that included each type of information - were, for example: search option, 1; interpreter service, 2; date of last update, 2; postal address, phone number, and e-mail service, 3; information in English, 2. None of the Web sites included information on waiting time or prices. Of the 31 patients surveyed, 12 had personal experience using the Internet and 4 had searched for medical information. The Internet users were significantly younger (mean age 47.8 years, range 28.4-66.8 years) than the nonusers (mean age 61.8 years, range 33.1-90.0 years) ( P= 0.007). Conclusions The hospitals' Web sites offer cancer patients and relatives useful information, but the Web sites were not impressive. PMID:11772545

Comparative chromosomal localization of 45S and 5S rDNAs and implications for genome evolution in Cucumis.

PubMed

Zhang, Zhen-Tao; Yang, Shu-Qiong; Li, Zi-Ang; Zhang, Yun-Xia; Wang, Yun-Zhu; Cheng, Chun-Yan; Li, Ji; Chen, Jin-Feng; Lou, Qun-Feng

2016-07-01

Ribosomal DNAs are useful cytogenetic markers for chromosome analysis. Studies investigating site numbers and distributions of rDNAs have provided important information for elucidating genome organization and chromosomal relationships of many species by fluorescence in situ hybridization. But relevant studies are scarce for species of the genus Cucumis, especially in wild species. In the present study, FISH was conducted to investigate the organization of 45S and 5S rDNA among 20 Cucumis accessions, including cultivars and wild accessions. Our results showed that the number of 45S rDNA sites varied from one to five pairs in different accessions, and most of these sites are located at the terminal regions of chromosomes. Interestingly, up to five pairs of 45S rDNA sites were observed in C. sativus var. sativus, the species which has the lowest chromosome number, i.e., 2n = 14. Only one pair of 5S rDNA sites was detected in all accessions, except for C. heptadactylus, C. sp, and C. spp that had two pairs of 5S rDNA sites. The distributions of 5S rDNA sites showed more variation than 45S rDNA sites. The phylogenetic analysis in this study showed that 45S and 5S rDNA have contrasting evolutionary patterns. We find that 5S rDNA has a polyploidization-related tendency towards the terminal location from an interstitial location but maintains a conserved site number, whereas the 45S rDNA showed a trend of increasing site number but a relatively conserved location.

Water-Quality Data for the Lower Russian River Basin, Sonoma County, California, 2003-2004

USGS Publications Warehouse

Anders, Robert; Davidek, Karl; Koczot, Kathryn M.

2006-01-01

In 2003, the U.S. Geological Survey, in cooperation with the Sonoma County Water Agency, began a study to determine the chemical, microbiological, and isotopic composition of the surface water and ground water in selected areas of the Lower Russian River Basin, Sonoma County, California. This report is a compilation of the hydrologic and water-quality data collected from 10 Russian River sites, 1 gravel-terrace pit site, 12 ground-water sites, 11 tributary sites including Mark West Creek, and 2 estuary sites between the city of Healdsburg and the Pacific Ocean, for the period August 2003 to September 2004. Field measurements made included streamflow, barometric pressure, dissolved oxygen, pH, specific conductance, and turbidity. Water samples were analyzed for nutrients, major ions, total and dissolved organic carbon, trace elements, mercury, wastewater compounds, total coliform, Escherichia coli, Enterococci, Clostridium perfringens, and the stable isotopes of hydrogen and oxygen. Discharge measurements and sampling techniques were modified to accommodate the very low summer flows at most of the tributaries, and discharge measurements were made with an acoustic Doppler velocity meter at the estuary river site to overcome the complexities associated with tidal influences.

Problematic use of social networking sites among urban school going teenagers

PubMed Central

Meena, Parth Singh; Mittal, Pankaj Kumar; Solanki, Ram Kumar

2012-01-01

Background: Social networking sites like Facebook, Orkut and Twitter are virtual communities where users can create individual public profiles, interact with real-life friends and meet other people based on shared interests. An exponential rise in usage of Social Networking Sites have been seen within the last few years. Their ease of use and immediate gratification effect on users has changed the way people in general and students in particular spend their time. Young adults, particularly teenagers tended to be unaware of just how much time they really spent on social networking sites. Negative correlates of Social Networking Sites usage include the decrease in real life social community participation and academic achievement, as well as relationship problems, each of which may be indicative of potential addiction. Aims: the aim of the study was to find out whether teenagers, specially those living in cities spend too much time on social networking websites. Materials and Methods: 200 subjects, both boys and girls were included in the cross sectional study who were given a 20 item Young's internet addiction test modified for social networking sites. The responses were analyzed using chi square test and Fisher's exact test. Results: 24.74% of the students were having occasional or ‘frequency’ problems while 2.02% of them were experiencing severe problems due to excessive time spent using social networking sites. Conclusion: With the ever increasing popularity of social media, teenagers are devoting significant time to social networking on websites and are prone to get ‘addicted’ to such form of online social interaction. PMID:24250039

Multidisciplinary study on anthropogenic landslides in Nepal

NASA Astrophysics Data System (ADS)

Puglia, Christopher; Derron, Marc-Henri; Nicolet, Pierrick; Sudmeier-Rieux, Karen; Jaboyedoff, Michel; Devkota, Sanjay

2013-04-01

Nepal is a country in which shallow landslide is a frequent phenomenon. Monsoon is the main triggering factor but anthropogenic influence is often significant too. Indeed, many infrastructures, such as roads or water pipes, are not built in a rigorous way because of a lack of funds and knowledge. In the present study we examine the technical, social and economic issues of landslide management for two sites in Nepal. The first site is located in Sanusiruwari VDC (Sindhupalchock district, central Nepal) and the second one in Namadi VDC (Ramecchap district, central Nepal). Both sites are affected by landslides induced by the construction of hydropower plants. These landslides may threaten the viability of the hydropower plants. At both sites the problems are quite similar, but the first site project is a private one and the second one is a public one implemented by the United Nations Development Programme (UNDP). For both sites, bioengineering methods using Vetiver (Vetyveria zizanioides) plantations is the main stabilization measure. To follow the progression of both landslides, fieldwork observations were conducted before and after the 2012 rainy season, including photogrammetric and distancemeter acquisitions. Main issues were discussed with communities and stakeholders of the hydropower projects through interviews and participatory risk mapping. Main issues include: lack of communication between the project managers and communities leading to conflict and the lack of maintenance of the bio-engineering sites, leading to less effective Vetiver growth and slope stabilization. Comparing the landslide management (technical, social and economic) of the two projects allows to point out some specific issues within an integrated risk perspective.

A medical consultation service on Facebook: descriptive analysis of questions answered.

PubMed

Helve, Otto

2014-09-04

Social media is used increasingly by the general public to access health information. However, a lack of models for health information distribution limits the presence of publicly funded services on social media sites. The goal of the study was to present a model for delivering child health information to parents through a social media site. A Facebook site was launched for 11 months based on a question-and-answer service produced by a pediatrician and open to Facebook users over 18 years old. If the answer did not include a further referral to a health care service provider, the question was considered comprehensively answered. The site was funded by a pharmaceutical company, and it included an advertisement of a pharmaceutical product for children's fever and pain. During the study, 768 questions were submitted: an average of 69.8 (SD 31.7) per month. There were 245,533 independent Facebook users on the site, with an average of 727.0 (SD 2280.6) per day. Infections were the most common theme in questions (355/768, 46.2%). Questions were more likely to be comprehensively answered if they were related to infections (279/355, 78.6%) than questions related to non-infectious symptoms (265/423, 64.2%, P=.003). On this site aimed at parents of small children, personalized answers were an effective way of delivering information. The service is likely to have reduced the need for further contacts with a health care service provider in more than half of the cases. The site could serve as a model for publicly funded health information distribution.

Full thickness skin grafts in periocular reconstructions: long-term outcomes.

PubMed

Rathore, Deepa S; Chickadasarahilli, Swaroop; Crossman, Richard; Mehta, Purnima; Ahluwalia, Harpreet Singh

2014-01-01

To evaluate the outcomes of eyelid reconstruction in patients who underwent full thickness skin grafts. A retrospective, noncomparative intervention study of patients who underwent periocular reconstruction with full thickness skin grafts between 2005 and 2011. One hundred consecutive Caucasian patients were included in the study, 54 women and 46 men. Mean follow up was 32 months. Indications for full thickness skin grafts were excision of eyelid tumors (98%) and cicatricial ectropion (2%). Site of lid defects were lower lid (60%), medial canthus (32%), upper lid (6%), and lateral canthus (2%). The skin graft donor sites were supraclavicular (44%), upper eyelid (24%), inner brachial (18%), and postauricular (14%).Early postoperative complications included lower eyelid graft contracture (1%) and partial failure (1%). Late sequelae included lower eyelid graft contracture (4%) and hypertrophic scarring (23%). Of the 23 patients with hypertrophic scar, 21 achieved good outcomes following massage with silicone gel and steroid ointment and 2 had persistent moderate lumpiness. No statistically significant association was found between graft hypertrophy and donor site or graft size. As high as 95% of all patients achieved good final eyelid position. Good color match was seen in 94% and graft hypopigmentation in 6%. An association between hypopigmentation and supraclavicular and inner brachial donor site was found to be statistically significant. Most patients (94%) achieved good eyelid position and color match. Majority (91%) of the early postoperative cicatricial sequelae can be reversed by massage, steroid ointment, and silicone gel application. Full thickness skin grafts have excellent graft survival rates and have minimal donor site morbidity.

75 FR 32221 - Whirlpool Corporation, Evansville Division, Including On-Site Leased Workers from Andrews...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-07

..., Evansville Division, Including On-Site Leased Workers from Andrews International, Inc., Evansville, IN... that workers leased from Andrews International, Inc. were employed on-site at the Evansville, Indiana... findings, the Department is amending this certification to include leased workers from Andrews...

Water supply studies. [management and planning of water supplies in California

NASA Technical Reports Server (NTRS)

Burgy, R. H.; Algazi, V. R.; Draeger, W. C.; Churchman, C. W.; Thomas, R. W.; Lauer, D. T.; Hoos, I.; Krumpe, P. F.; Nichols, J. D.; Gialdini, M. J.

1973-01-01

The primary test site for water supply investigations continues to be the Feather River watershed in northeastern California. This test site includes all of the area draining into and including the Oroville Reservoir. The principal effort is to determine the extent to which remote sensing techniques, when properly employed, can provide information useful to those persons concerned with the management and planning of lands and facilities for the production of water, using the Oroville Reservoir and the California Water Project as the focus for the study. In particular, emphasis is being placed on determining the cost effectiveness of information derived through remote sensing as compared with that currently being derived through more conventional means.

Archaeology: site studies, activation analysis, preservation, and remote sensing (a bibliography with abstracts). Report for 1964-Nov 76. [135 abstracts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lehmann, E.J.

1976-12-01

This bibliography was prepared in order to bring together Federally funded research relating to archaeology. It is divided into two sections. The first deals with the chemical analysis of archaeological specimens primarily using activation analysis. Articles studied include metals, pottery, coins, paintings, soils, glass, and paper from Medieval, Grecian, Egyptian, Mayan, and prehistoric times. The second section cites other archaeological research including results of excavations from all over the United States. Also covered is work on preservation of artifacts and remote sensing for site location. (This updated bibliography contains 135 abstracts, 18 of which are new entries to the previousmore » edition.) (GRA)« less

Archaeology: site studies, activation analysis, preservation, and remote sensing. volume 1. 1964-1976 (a bibliography with abstracts). Report for 1964-1976

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cavagnaro, D.M.

1978-11-01

This bibliography was prepared in order to bring together Federally-funded research relating to archaeology. It is divided into two sections. The first deals with the chemical analysis of archaeological specimens primarily using activation analysis. Articles studied include metals, pottery, coins, paintings, soils, glass, and paper from Medieval, Grecian, Egyptian, Mayan, and prehistoric times. The second section cites other archaeological research, including results of excavations from the United States. Also covered is work on preservation of artifacts and remote sensing for site location. (This updated bibliography contains 137 abstracts, none of which are new entries to the previous edition.)

Nurses' perceptions of involvement in Thunder Project. American Association of Critical-Care Nurses Thunder Project task force.

PubMed

1995-03-01

The American Association of Critical-Care Nurse's (AACN) Thunder Project was conceptualized and developed to provide critical-care nurses with a research protocol ready for institutional review and implementation. Project goals included providing a research package (protocol, educational, and data collection materials) and a topic of clinical significance to critical-care nurses. Site coordinators and research associates were identified at participating institutions to coordinate and implement all study activities. In this article, an evaluation study undertaken to recount perceptions of site coordinators and research associates in relation to project goals and research experience is described. Data demonstrated that study goals were achieved, and research experience was considered professionally enhancing. Written comments described barriers to project implementation at participating sites. Obtaining informed consent and physician approval and/or cooperation were identified as significant barriers to implementation at some sites.

A Retrospective Study on Genetic Heterogeneity within Treponema Strains: Subpopulations Are Genetically Distinct in a Limited Number of Positions.

PubMed

Čejková, Darina; Strouhal, Michal; Norris, Steven J; Weinstock, George M; Šmajs, David

2015-01-01

Pathogenic uncultivable treponemes comprise human and animal pathogens including agents of syphilis, yaws, bejel, pinta, and venereal spirochetosis in rabbits and hares. A set of 10 treponemal genome sequences including those of 4 Treponema pallidum ssp. pallidum (TPA) strains (Nichols, DAL-1, Mexico A, SS14), 4 T. p. ssp. pertenue (TPE) strains (CDC-2, Gauthier, Samoa D, Fribourg-Blanc), 1 T. p. ssp. endemicum (TEN) strain (Bosnia A) and one strain (Cuniculi A) of Treponema paraluisleporidarum ecovar Cuniculus (TPLC) were examined with respect to the presence of nucleotide intrastrain heterogeneous sites. The number of identified intrastrain heterogeneous sites in individual genomes ranged between 0 and 7. Altogether, 23 intrastrain heterogeneous sites (in 17 genes) were found in 5 out of 10 investigated treponemal genomes including TPA strains Nichols (n = 5), DAL-1 (n = 4), and SS14 (n = 7), TPE strain Samoa D (n = 1), and TEN strain Bosnia A (n = 5). Although only one heterogeneous site was identified among 4 tested TPE strains, 16 such sites were identified among 4 TPA strains. Heterogeneous sites were mostly strain-specific and were identified in four tpr genes (tprC, GI, I, K), in genes involved in bacterial motility and chemotaxis (fliI, cheC-fliY), in genes involved in cell structure (murC), translation (prfA), general and DNA metabolism (putative SAM dependent methyltransferase, topA), and in seven hypothetical genes. Heterogeneous sites likely represent both the selection of adaptive changes during infection of the host as well as an ongoing diversifying evolutionary process.

Assessment of function and clinical utility of alcohol and other drug web sites: An observational, qualitative study

PubMed Central

2011-01-01

Background The increasing popularity and use of the internet makes it an attractive option for providing health information and treatment, including alcohol/other drug use. There is limited research examining how people identify and access information about alcohol or other drug (AOD) use online, or how they assess the usefulness of the information presented. This study examined the strategies that individuals used to identify and navigate a range of AOD websites, along with the attitudes concerning presentation and content. Methods Members of the general community in Brisbane and Roma (Queensland, Australia) were invited to participate in a 30-minute search of the internet for sites related to AOD use, followed by a focus group discussion. Fifty one subjects participated in the study across nine focus groups. Results Participants spent a maximum of 6.5 minutes on any one website, and less if the user was under 25 years of age. Time spent was as little as 2 minutes if the website was not the first accessed. Participants recommended that AOD-related websites should have an engaging home or index page, which quickly and accurately portrayed the site's objectives, and provided clear site navigation options. Website content should clearly match the title and description of the site that is used by internet search engines. Participants supported the development of a portal for AOD websites, suggesting that it would greatly facilitate access and navigation. Treatment programs delivered online were initially viewed with caution. This appeared to be due to limited understanding of what constituted online treatment, including its potential efficacy. Conclusions A range of recommendations arise from this study regarding the design and development of websites, particularly those related to AOD use. These include prudent use of text and information on any one webpage, the use of graphics and colours, and clear, uncluttered navigation options. Implications for future website development are discussed. PMID:21545748

Safety and Feasibility of Transradial Access for Visceral Interventions in Patients with Thrombocytopenia.

PubMed

Titano, J J; Biederman, D M; Marinelli, B S; Patel, R S; Kim, E; Tabori, N E; Nowakowski, F S; Lookstein, R A; Fischman, A M

2016-05-01

Transradial access (TRA) has shown lower morbidity and decreased bleeding complications compared to transfemoral access. This study evaluates the safety and feasibility of TRA in thrombocytopenic patients undergoing visceral interventions. Patients who underwent visceral interventions via the radial artery with platelet count less than or equal to 50,000/µL were included in the study. Outcome variables included technical success, access site, bleeding, transfusion, and neurological complications. From July 1, 2012, to May 31, 2015, a total of 1353 peripheral interventions via TRA were performed, of which 85 procedures were performed in 64 patients (mean age 62.2 years) with a platelet count <50,000/µL (median 39,000/µL). Interventions included chemoembolization (n = 46), selective internal radiation therapy (n = 30), and visceral embolization (n = 9). Technical success was 97.6% with two cases of severe vessel spasm requiring ipsilateral femoral crossover. There was no major access site, bleeding, or neurological adverse events at 30 days. Minor access site hematomas occurred in five cases (5.9%) and were treated conservatively in all cases. Pre-procedural platelet transfusions were administered in 23 (27.1%) cases. There was no statistically significant difference in access site or bleeding complications between the transfused and nontransfused groups. Transradial visceral interventions in patients with thrombocytopenia are both feasible and safe, possibly without the need for platelet transfusions.

Class 1 overview of cultural resources for the Western Area Power Administration Salt Lake City Area Integrated Projects electric power marketing environmental impact statement

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moeller, K.L.; Malinowski, L.M.; Hoffecker, J.F.

1993-11-01

Argonne National Laboratory conducted an inventory of known archaeological and historic sites in areas that could be affected by the hydropower operation alternatives under analysis in the power marketing environmental impact statement for the Western Area Power Administration`s Salt Lake City Area Integrated Projects. The study areas included portions of the Green River (Flaming Gorge Dam to Cub Creek) in Utah and Colorado and the Gunnison River (Blue Mesa Reservoir to Crystal Dam) in Colorado. All previous archaeological surveys and previously recorded prehistoric and historic sites, structures, and features were inventoried and plotted on maps (only survey area maps aremore » included in this report). The surveys were classified by their level of intensity, and the sites were classified according to their age, type, and contents. These data (presented here in tabular form) permit a general assessment of the character and distribution of archaeological remains in the study areas, as well as an indication of the sampling basis for such an assessment. To provide an adequate context for the descriptions of the archaeological and historic sites, this report also presents overviews of the environmental setting and the regional prehistory, history, and ethnography for each study area.« less

Application of Spatial Data Modeling and Geographical Information Systems (GIS) for Identification of Potential Siting Options for Various Electrical Generation Sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mays, Gary T; Belles, Randy; Blevins, Brandon R

2012-05-01

Oak Ridge National Laboratory (ORNL) initiated an internal National Electric Generation Siting Study, which is an ongoing multiphase study addressing several key questions related to our national electrical energy supply. This effort has led to the development of a tool, OR-SAGE (Oak Ridge Siting Analysis for power Generation Expansion), to support siting evaluations. The objective in developing OR-SAGE was to use industry-accepted approaches and/or develop appropriate criteria for screening sites and employ an array of Geographic Information Systems (GIS) data sources at ORNL to identify candidate areas for a power generation technology application. The initial phase of the study examinedmore » nuclear power generation. These early nuclear phase results were shared with staff from the Electric Power Research Institute (EPRI), which formed the genesis and support for an expansion of the work to several other power generation forms, including advanced coal with carbon capture and storage (CCS), solar, and compressed air energy storage (CAES). Wind generation was not included in this scope of work for EPRI. The OR-SAGE tool is essentially a dynamic visualization database. The results shown in this report represent a single static set of results using a specific set of input parameters. In this case, the GIS input parameters were optimized to support an economic study conducted by EPRI. A single set of individual results should not be construed as an ultimate energy solution, since US energy policy is very complex. However, the strength of the OR-SAGE tool is that numerous alternative scenarios can be quickly generated to provide additional insight into electrical generation or other GIS-based applications. The screening process divides the contiguous United States into 100 x 100 m (1-hectare) squares (cells), applying successive power generation-appropriate site selection and evaluation criteria (SSEC) to each cell. There are just under 700 million cells representing the contiguous United States. If a cell meets the requirements of each criterion, the cell is deemed a candidate area for siting a specific power generation form relative to a reference plant for that power type. Some SSEC parameters preclude siting a power plant because of an environmental, regulatory, or land-use constraint. Other SSEC assist in identifying less favorable areas, such as proximity to hazardous operations. All of the selected SSEC tend to recommend against sites. The focus of the ORNL electrical generation source siting study is on identifying candidate areas from which potential sites might be selected, stopping short of performing any detailed site evaluations or comparisons. This approach is designed to quickly screen for and characterize candidate areas. Critical assumptions supporting this work include the supply of cooling water to thermoelectric power generation; a methodology to provide an adequate siting footprint for typical power plant applications; a methodology to estimate thermoelectric plant capacity while accounting for available cooling water; and a methodology to account for future ({approx}2035) siting limitations as population increases and demands on freshwater sources change. OR-SAGE algorithms were built to account for these critical assumptions. Stream flow is the primary thermoelectric plant cooling source evaluated in this study. All cooling was assumed to be provided by a closed-cycle cooling (CCC) system requiring makeup water to account for evaporation and blowdown. Limited evaluations of shoreline cooling and the use of municipal processed water (gray) cooling were performed. Using a representative set of SSEC as input to the OR-SAGE tool and employing the accompanying critical assumptions, independent results for the various power generation sources studied were calculated.« less

Veterans Aging Cohort Study (VACS)

PubMed Central

Justice, Amy C.; Dombrowski, Elizabeth; Conigliaro, Joseph; Fultz, Shawn L.; Gibson, Deborah; Madenwald, Tamra; Goulet, Joseph; Simberkoff, Michael; Butt, Adeel A.; Rimland, David; Rodriguez-Barradas, Maria C.; Gibert, Cynthia L.; Oursler, Kris Ann K.; Brown, Sheldon; Leaf, David A.; Goetz, Matthew B.; Bryant, Kendall

2010-01-01

Background The Veterans Aging Cohort Study (VACS) is a study of human immunodeficiency virus (HIV) infected and uninfected patients seen in infectious disease and general medical clinics. VACS includes the earlier 3 and 5 site studies (VACS 3 and VACS 5) as well as the ongoing 8 site study. Objectives We sought to provide background and context for analyses based upon VACS data, including study design and rationale as well as its basic protocol and the baseline characteristics of the enrolled sample. Research Design We undertook a prospectively consented multisite observational study of veterans in care with and without HIV infection. Measures Data were derived from patient and provider self report, telephone interviews, blood and DNA samples, focus groups, and full access to the national VA “paperless” electronic medical record system. Results More than 7200 veterans have been enrolled in at least one of the studies. The 8 site study (VACS) has enrolled 2979 HIV-infected and 3019 HIV-uninfected age–race–site matched comparators and has achieved stratified enrollment targets for race/ethnicity and age and 99% of its total target enrollment as of October 30, 2005. Participants in VACS are similar to other veterans receiving care within the VA. VACS participants are older and more predominantly black than those reported by the Centers for Disease Control. Conclusions VACS has assembled a rich, in-depth, and representative sample of veterans in care with and without HIV infection to conduct longitudinal analyses of questions concerning the association between alcohol use and related comorbid and AIDS-defining conditions. PMID:16849964

National hydroelectric power resources study. Preliminary inventory of hydropower resources. Volume 1. Pacific Northwest region

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1979-07-01

The preliminary inventory and analysis procedures provide a comprehensive assessment of the undeveloped hydroelectric power potential in the US and determines which sites merit more thorough investigation. Over 5400 existing structures have been identified as having the physical potential to add hydropower plants or increase hydropower output thereby increasing our present hydropower capacity from a total of 64,000 MW to 158,000 MW and our energy from 280,000 GWH to 503,000 GWH. While the physical potential for this increase is clearly available, some of these projects will undoubtedly not satisfy more-detailed economic analysis as well as the institutional and environmental criteriamore » which will be imposed upon them. Summary tables include estimates of the potential capacity and energy at each site in the inventory. In some cases, individual projects may be site alternatives to others in the same general location, when only one can be considered for hydropower development. The number of sites per state is identified, but specific information is included for only the sites in Alaska, Idaho, Oregon, and Washington in this first volume.« less

Nuclear facility decommissioning and site remedial actions: a selected bibliography. Volume 5

DOE Office of Scientific and Technical Information (OSTI.GOV)

Owen, P.T.; Knox, N.P.; Chilton, B.D.

1984-09-01

This bibliography of 756 references with abstracts on the subject of nuclear facility decommissioning, uranium mill tailings management, and site remedial actions is the fifth in a series of annual reports prepared for the US Department of Energy, Division of Remedial Action Projects. Foreign as well as domestic literature of all types - technical reports, progress reports, journal articles, conference papers, symposium proceedings, theses, books, patents, legislation, and research project descriptions - has been included in this publication. The bibliography contains scientific (basic research as well as applied technology), economic, regulatory, and legal literature pertinent to the US Department ofmore » Energy's Remedial Action Program. Major chapters are: (1) Surplus Facilities Management Program; (2) Nuclear Facilities Decommissioning; (3) Formerly Utilized Sites Remedial Action Program; (4) Uranium Mill Tailings Remedial Action Program; (5) Grand Junction Remedial Action Program; (6) Uranium Mill Tailings Management; and (7) Technical Measurements Center. Chapter sections for chapters 1, 2, 4, and 6 include Design, Planning, and Regulations; Environmental Studies and Site Surveys; Decontamination Studies; Dismantlement and Demolition; Site Stabilization and Reclamation; Waste Disposal; Remedial Action Experience; and General Studies. The references within each chapter or section are arranged alphabetically by leading author. References having no individual author are arranged by corporate author or by title. Indexes are provided for the categories of author, corporate affiliation, title, publication description, geographic location, and keywords. The Appendix contains a list of frequently used acronyms.« less

Adjunctive Non-Surgical Therapy of Inflamed Periodontal Pockets During Maintenance Therapy Using Diode Laser: A Randomized Clinical Trial.

PubMed

Nguyen, Naomi-Trang; Byarlay, Matthew R; Reinhardt, Richard A; Marx, David B; Meinberg, Trudy A; Kaldahl, Wayne B

2015-10-01

Numerous studies have documented the clinical outcomes of laser therapy for untreated periodontitis, but very few have reported on lasers treating inflamed pockets during maintenance therapy. The aim of this study is to compare the effectiveness of scaling and root planing (SRP) plus the adjunctive use of diode laser therapy to SRP alone on changes in the clinical parameters of disease and on the gingival crevicular fluid (GCF) inflammatory mediator interleukin-1β (IL-1β) in patients receiving regular periodontal maintenance therapy. This single-masked and randomized, controlled, prospective study includes 22 patients receiving regular periodontal maintenance therapy who had one or more periodontal sites with a probing depth (PD) ≥ 5 mm with bleeding on probing (BOP). Fifty-six sites were treated with SRP and adjunctive laser therapy (SRP + L). Fifty-eight sites were treated with SRP alone. Clinical parameters, including PD, clinical attachment level (CAL), and BOP, and GCF IL-1β levels were measured immediately before treatment (baseline) and 3 months after treatment. Sites treated with SRP + L and SRP alone resulted in statistically significant reductions in PD and BOP and gains in CAL. These changes were not significantly different between the two therapies. Similarly, differences in GCF IL-1β levels between SRP + L and SRP alone were not statistically significant. In periodontal maintenance patients, SRP + L did not enhance clinical outcomes compared to SRP alone in the treatment of inflamed sites with ≥ 5 mm PD.

76 FR 2145 - International Paper Company, Franklin Pulp & Paper Mill, Including On-Site Leased Workers From...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-12

... Company, Franklin Pulp & Paper Mill, Including On-Site Leased Workers From Railserve, Franklin, VA..., applicable to workers and former workers of International Paper Company, Franklin Pulp & Paper Mill, Franklin... follows: All workers International Paper Company, Franklin Pulp & Paper Mill, including on-site leased...

75 FR 76037 - General Motors Corporation Grand Rapids Metal Center Metal Fabricating Division Including On-Site...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-07

... Corporation Grand Rapids Metal Center Metal Fabricating Division Including On-Site Leased Workers From... Corporation, Grand Rapids Metal Center, Metal Fabricating Division, including on- site leased workers from... of metal stampings and sub- assembled metal sheet components. The company reports that workers leased...

78 FR 70580 - Amphenol Backplane Systems, Including On-Site Leased Workers From Technical Needs and National...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-26

... Systems, Including On-Site Leased Workers From Technical Needs and National Engineering, Nashua, New... to the production of electrical connectors and backplane assemblies. The subject worker group includes on-site leased workers from Technical Needs and National Engineering. Workers of the subject firm...

75 FR 39051 - Allstate Insurance Company, Altoona Express Market Claim Office, Including On-Site Leased Workers...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-07

... former workers of Allstate Insurance Company, Altoona Express Market Claim Office, including on- site... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-73,536] Allstate Insurance Company, Altoona Express Market Claim Office, Including On-Site Leased Workers From Kelly Services...

76 FR 175 - Faurecia Emissions Control Technologies Including On-Site Leased Workers From Adecco Employment...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-03

... Technologies Including On-Site Leased Workers From Adecco Employment Servcies and Emcon Technologies, Troy, MI..., applicable to workers of Faurecia Emissions Control Technologies, Troy, Michigan, including on-site leased workers from Adecco Employment Services, Troy, Michigan. The Department's notice of determination was...

75 FR 62423 - Barnstead Thermolyne Corporation, a Subsidiary of Thermo Fisher Scientific, Including On-Site...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-08

... related to the production of scientific laboratory equipment. New information shows that workers leased... Corporation, a Subsidiary of Thermo Fisher Scientific, Including On-Site Leased Workers From Sedona Staffing... Scientific, including on- site leased workers from Sedona Staffing, Dubuque, Iowa. The notice was published...

75 FR 38128 - Ceva Freight, LLC, Dell Logistics Division, Including On-Site Leased Workers From Prologistix and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-01

... Logistics Division, Including On-Site Leased Workers From Prologistix and Employment Staffing Solutions... 19, 2010, applicable to workers of CEVA Freight, LLC, Dell Logistics Division, including on-site..., North Carolina location of CEVA Freight, LLC, Dell Logistics Division. The Department has determined...

78 FR 12358 - UBS Financial Services, Inc., Wealth Management Americas Operations, Including On-Site Leased...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-22

..., Inc., Wealth Management Americas Operations, Including On-Site Leased Workers From Leafstone... Services, Inc., Wealth Management Americas Operations (UBS), Weehawken, New Jersey. The workers are engaged... to include all leased workers on-site at UBS Financial Services, Inc., Wealth Management Americas...

75 FR 11921 - Heritage Aviation, Ltd., Including On-Site Leased Workers From Global Technical Services and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-12

... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-72,924] Heritage Aviation, Ltd., Including On-Site Leased Workers From Global Technical Services and Global, Inc. (Global Employment... from Heritage Aviation, Ltd, including on-site leased workers from Global Technical Services, Grand...

77 FR 14832 - Plumchoice, Inc., Including On-Site Leased Workers From Balance Staffing, Insight Global Staffing...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-13

...., Including On-Site Leased Workers From Balance Staffing, Insight Global Staffing, and Technisource..., 2012, applicable to workers of PlumChoice, Inc., including on-site leased workers from Balance Staffing... leased workers from Balance Staffing, Insight Global Staffing, and Technisource, Scarborough, Maine, who...

78 FR 28642 - Eastman Kodak Company, Electrographic Print Solutions, Including On-Site Leased Workers From...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-15

... Kodak Company, Electrographic Print Solutions, Including On-Site Leased Workers From Adecco and Datrose, Spencerport, New York; Eastman Kodak Company, IPS, Including On-Site Leased Workers From Adecco, Dayton, Ohio... Trade Adjustment Assistance (TAA) filed on behalf of Eastman Kodak Company, Electrographic Print...

76 FR 54793 - Westpoint Home, Inc., Manufacturing Division, Including On-Site Leased Workers from Manpower...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-02

... Home, Inc., Manufacturing Division, Including On-Site Leased Workers from Manpower, Greenville, AL; Westpoint Home, Inc., Distribution Center, Including On-Site Leased Workers from Manpower, Greenville, AL..., applicable to workers of WestPoint Home, Inc., Manufacturing Division, Greenville, Alabama and WestPoint Home...

75 FR 45159 - Stanadyne Corporation, Including On-Site Leased Workers From Infini-Staff, Staffing Now and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-02

..., Including On-Site Leased Workers From Infini-Staff, Staffing Now and Apollo Professional Solutions, Inc... shows that workers leased from Apollo Professional Solutions were employed on-site at the Windsor..., the Department is amending this certification to include workers leased from Apollo Professional...

A Cross-Industry Review of B2B Critical Success Factors.

ERIC Educational Resources Information Center

Eid, Riyad; Trueman, Myfanwy; Ahmed, Abdel Moneim

2002-01-01

Presents a comprehensive review of B2B (business-to- business) international Internet marketing and identifies 21 critical success factors in five categories: marketing strategy, including management support, strategic goals, and collaboration; Web site factors, including Web site design; global factors, including multilanguage sites and cultural…

75 FR 20386 - Trane a Subsidiary of Ingersoll Rand Including On-Site Leased Workers From Aerotek, Express...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-19

... Ingersoll Rand Including On-Site Leased Workers From Aerotek, Express Personnel Services, Select Staffing... Ingersoll Rand, including on-site leased workers from Aerotek, Express Personnel Staffing, and Select... from Aerotek, Express Personnel Staffing, Select Staffing, and Mechanical Contractors, Inc., Pueblo...

Comprehensive Calibration and Validation Site for Information Remote Sensing

NASA Astrophysics Data System (ADS)

Li, C. R.; Tang, L. L.; Ma, L. L.; Zhou, Y. S.; Gao, C. X.; Wang, N.; Li, X. H.; Wang, X. H.; Zhu, X. H.

2015-04-01

As a naturally part of information technology, Remote Sensing (RS) is strongly required to provide very precise and accurate information product to serve industry, academy and the public at this information economic era. To meet the needs of high quality RS product, building a fully functional and advanced calibration system, including measuring instruments, measuring approaches and target site become extremely important. Supported by MOST of China via national plan, great progress has been made to construct a comprehensive calibration and validation (Cal&Val) site, which integrates most functions of RS sensor aviation testing, EO satellite on-orbit caration and performance assessment and RS product validation at this site located in Baotou, 600km west of Beijing. The site is equipped with various artificial standard targets, including portable and permanent targets, which supports for long-term calibration and validation. A number of fine-designed ground measuring instruments and airborne standard sensors are developed for realizing high-accuracy stepwise validation, an approach in avoiding or reducing uncertainties caused from nonsynchronized measurement. As part of contribution to worldwide Cal&Val study coordinated by CEOS-WGCV, Baotou site is offering its support to Radiometric Calibration Network of Automated Instruments (RadCalNet), with an aim of providing demonstrated global standard automated radiometric calibration service in cooperation with ESA, NASA, CNES and NPL. Furthermore, several Cal&Val campaigns have been performed during the past years to calibrate and validate the spaceborne/airborne optical and SAR sensors, and the results of some typical demonstration are discussed in this study.

40 CFR 35.6105 - State-lead remedial Cooperative Agreements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... the name and position of those individuals who will be responsible for coordinating the State offices... narrative statement, including the following: (i) A site description, including a discussion of the location of each site, the physical characteristics of each site (site geology and proximity to drinking water...

40 CFR 35.6105 - State-lead remedial Cooperative Agreements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... the name and position of those individuals who will be responsible for coordinating the State offices... narrative statement, including the following: (i) A site description, including a discussion of the location of each site, the physical characteristics of each site (site geology and proximity to drinking water...

40 CFR 35.6105 - State-lead remedial Cooperative Agreements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... the name and position of those individuals who will be responsible for coordinating the State offices... narrative statement, including the following: (i) A site description, including a discussion of the location of each site, the physical characteristics of each site (site geology and proximity to drinking water...

40 CFR 35.6105 - State-lead remedial Cooperative Agreements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... the name and position of those individuals who will be responsible for coordinating the State offices... narrative statement, including the following: (i) A site description, including a discussion of the location of each site, the physical characteristics of each site (site geology and proximity to drinking water...

OriDB, the DNA replication origin database updated and extended.

PubMed

Siow, Cheuk C; Nieduszynska, Sian R; Müller, Carolin A; Nieduszynski, Conrad A

2012-01-01

OriDB (http://www.oridb.org/) is a database containing collated genome-wide mapping studies of confirmed and predicted replication origin sites. The original database collated and curated Saccharomyces cerevisiae origin mapping studies. Here, we report that the OriDB database and web site have been revamped to improve user accessibility to curated data sets, to greatly increase the number of curated origin mapping studies, and to include the collation of replication origin sites in the fission yeast Schizosaccharomyces pombe. The revised database structure underlies these improvements and will facilitate further expansion in the future. The updated OriDB for S. cerevisiae is available at http://cerevisiae.oridb.org/ and for S. pombe at http://pombe.oridb.org/.

DFT investigation of the interaction of gold nanoclusters with poly(amidoamine) PAMAM G0 dendrimer

NASA Astrophysics Data System (ADS)

Camarada, M. B.

2016-06-01

The interaction between PAMAM G0 and gold nanoclusters Aun (n = 2, 4, 6, and 8) was studied theoretically at DFT level. Different coordination sites were explored, including internal and superficial coordination. All stable complexes exhibited external interaction with the amine or carbonyl site, while the core site coordination was not favored. The more stable binding of Aun was registered with the terminal amine group, while the binding at the amide site was relatively weaker. The vertical first ionization potential, electron affinity, Fermi level, and the HOMO-LUMO gap of PAMAM and Aun-PAMAM G0 complexes were also analyzed.

OLEM Center for Program Analysis Site Analysis Data

EPA Pesticide Factsheets

This asset includes environmental justice-related analyses of population located within a mile of Superfund and RCRA Corrective Action sites. It characterizes demographics and socio-economic characteristics of near-site communities as compared to the average U.S. population. It also examined children of up to 17 years of age living within 1 mile of SF and RCRA CA sites where human health protective measures may not have been in place. It compared data on the health status of these children to the status of all children in the U.S. Information from this study contributed to the America's Children and the Environment (ACE) report for 2013.

Impact of Demographic Siting Criteria and Environmental Suitability on Land Availability for Nuclear Reactor Siting

NASA Technical Reports Server (NTRS)

Hansen, K. L.

1982-01-01

The effect of population and certain environmental characteristics on the availability of land for siting nuclear power plants was assessed. The study area, consisting of the 48 contiguous states, was divided into 5 kilometer (km) square grid cells yielding a total of 600,000 cells. Through the use of a modern geographic information system, it was possible to provide a detailed analysis of a quite large area. Numerous maps and statistical tables were produced, the detail of which were limited only by available data. Evaluation issues included population density, restricted lands, seismic hardening, site preparation, water availability, and cost factors.

Photosynthesis and the web: 2001.

PubMed

Orr, L

2001-01-01

First, a brief history of the Internet and the World Wide Web is presented. This is followed by relevant information on photosynthesis-related web sites grouped into several categories: (1) large group sites, (2) comprehensive overview sites, (3) specific subject sites, (4) individual researcher sites, (5) kindergarten through high school (K-12) educational sites, (6) books and journals, and, 7) other useful sites. A section on searching the Web is also included. Finally, we have included an appendix with all of the web sites discussed herein as well as other web sites that space did not allow. Readers are requested to send comments, corrections and additions to gov@uiuc.edu.

Reducing risk and increasing confidence of decision making at a lower cost: In-situ pXRF assessment of metal-contaminated sites.

PubMed

Rouillon, Marek; Taylor, Mark P; Dong, Chenyin

2017-10-01

This study evaluates the in-situ use of field portable X-ray Fluorescence (pXRF) for metal-contaminated site assessments, and assesses the advantages of increased sampling to reduce risk, and increase confidence of decision making at a lower cost. Five metal-contaminated sites were assessed using both in-situ pXRF and ex-situ inductively coupled plasma mass spectrometry (ICP-MS) analyses at various sampling resolutions. Twenty second in-situ pXRF measurements of Mn, Zn and Pb were corrected using a subset of parallel ICP-MS measurements taken at each site. Field and analytical duplicates revealed sampling as the major contributor (>95% variation) to measurement uncertainties. This study shows that increased sampling led to several benefits including more representative site characterisation, higher soil-metal mapping resolution, reduced uncertainty around the site mean, and reduced sampling uncertainty. Real time pXRF data enabled efficient, on-site decision making for further judgemental sampling, without the need to return to the site. Additionally, in-situ pXRF was more cost effective than the current approach of ex-situ sampling and ICP-MS analysis, even with higher sampling at each site. Lastly, a probabilistic site assessment approach was applied to demonstrate the advantages of integrating estimated measurement uncertainties into site reporting. Copyright © 2017 Elsevier Ltd. All rights reserved.

A study in usability: redesigning a health sciences library's mobile site.

PubMed

Rosario, Jovy-Anne; Ascher, Marie T; Cunningham, Diana J

2012-01-01

A mobile site redesign was conducted at a medium-sized academic health sciences library with the goal of creating a site that meets the mobile information needs of its users. The redesign phases included (1) needs assessment, (2) usability testing, and (3) site design. The survey results showed that Apple devices were the most prevalent; the most desirable activities performed on a mobile site were searching for articles, accessing full-text articles and e-books, searching databases, and searching the catalog. These activities guided the development of the usability testing tasks and the redesign. All phases were completed within six months, and the total project cost was $50 for incentive purchases. Copyright © Taylor & Francis Group, LLC

A content analysis of Web sites promoting smoking culture and lifestyle.

PubMed

Ribisl, Kurt M; Lee, Rebecca E; Henriksen, Lisa; Haladjian, Harry H

2003-02-01

The present study examined smoking culture and lifestyle Web sites listed on Yahoo!, a popular Internet search catalog, to determine whether the sites were easily accessible to youth, featured age or health warnings, and mentioned specific tobacco brands. A content analysis of photographs on these sites assessed the demographics of individuals depicted and the amount of smoking and nudity in the photographs. The sample included 30 Web sites, all of which were accessible to youth and did not require age verification services to enter them. Cigarette brand names were mentioned in writing on 35% of the sites, and brand images were present on 24% of the sites. Nearly all of the photographs (95%) depicted smoking, 92% featured women, and 7% contained partial or full nudity. These results underscore the need for greater research and monitoring of smoking-related Internet content by health educators and tobacco control advocates.

Framing medical tourism: an examination of appeal, risk, convalescence, accreditation, and interactivity in medical tourism web sites.

PubMed

Mason, Alicia; Wright, Kevin B

2011-02-01

This exploratory study analyzed the content of medical tourism Web sites in an attempt to examine how they convey information about benefits and risks of medical procedures, how they frame credibility, and the degree to which these Web sites include interactive features for consumers. Drawing upon framing theory, the researchers content analyzed a sample of 66 medical tourism Web sites throughout the world. The results indicated that medical tourism Web sites largely promote the benefits of medical procedures while downplaying the risks, and relatively little information regarding the credibility of these services appears. In addition, the presentation of benefits/risks, credibility, and Web site interactivity were found to differ by region and type of facility. The authors discuss the implications of these findings concerning the framing of medical tourism Web site content, future directions for research, and limitations.

Implementation of a DOD ELAP Conforming Quality System at a FUSRAP Site Field Temporary Radiological Screening Laboratory - 13500

DOE Office of Scientific and Technical Information (OSTI.GOV)

Winters, M.S.; McElheny, G.; Houston, L.M.

2013-07-01

A case study is presented on specific program elements that supported the transition of a temporary field radiological screening lab to an accredited operation capable of meeting client quality objectives for definitive results data. The temporary field lab is located at the Formerly Utilized Sites Remedial Action Program Linde Site in Tonawanda, NY. The site is undergoing remediation under the direction of the United States Army Corps of Engineers - Buffalo District, with Cabrera Services Inc. as the remediation contractor and operator of the on-site lab. Analysis methods employed in the on-site lab include gross counting of alpha and betamore » particle activity on swipes and air filters and gamma spectroscopy of soils and other solid samples. A discussion of key program elements and lessons learned may help other organizations considering pursuit of accreditation for on-site screening laboratories. (authors)« less

An integrated pest control strategy against the Asian tiger mosquito in northern Italy: a case study.

PubMed

Baldacchino, Frédéric; Bussola, Francesca; Arnoldi, Daniele; Marcantonio, Matteo; Montarsi, Fabrizio; Capelli, Gioia; Rosà, Roberto; Rizzoli, Annapaola

2017-01-01

In Europe, Aedes albopictus is an invasive mosquito species known to be a major nuisance as well as a vector of a range of arboviruses. A number of studies have indicated that community participation programmes are an effective pest control tool to reduce mosquito populations. However, few studies have evaluated the effectiveness of a community-based approach in Europe. In this study, we examined two Ae. albopictus control strategies that implemented a community-based approach in northern Italy: one was a partial intervention that included a public education campaign and the larviciding of public spaces, and the other was a full intervention that additionally included a door-to-door campaign. This latter consisted of going door to door actively to educate residents about control measures and deliver larvicide tablets for treating catch basins at home. A site where no intervention measures were carried out was used as a control. In the site where a full intervention was carried out, Ae. albopictus egg density was 1.6 times less than at the site that received partial intervention, and 1.9 times less than at the non-intervention site. No significant reduction in egg density was achieved in the partial intervention site. In our study, Ae. albopictus populations were most effectively reduced by larviciding both public and private catch basins. Door-to-door education was effective in convincing residents to apply control measures on their property; however, this method was labour intensive and costly. It may be possible to reduce personnel costs by involving volunteers or using a 'hot spot' approach. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

BOREAS TGB-5 CO2, CH4 and CO Chamber Flux Data Over the NSA

NASA Technical Reports Server (NTRS)

Burke, Roger; Hall, Forrest G. (Editor); Conrad, Sara K. (Editor); Zepp, Richard

2000-01-01

The BOReal Ecosystem-Atmosphere Study Trace Gas Biogeochemistry (BOREAS TGB-5) team collected a variety of trace gas concentration and flux measurements at several NSA sites. This data set contains carbon dioxide (CO2), methane (CH4), and carbon monoxide (CO) chamber flux measurements conducted in 1994 at upland forest sites that experienced stand-replacement fires. These measurements were acquired to understand the impact of fires on soil biogeochemistry and related changes in trace gas exchange in boreal forest soils. Relevant ancillary data, including data concerning the soil temperature, solar irradiance, and information from nearby un-burned control sites, are included to provide a basis for modeling the regional impacts of fire and climate changes on trace gas biogeochemistry. The data are provided in tabular ASCII files.

Disseminated sinus histiocytosis with massive lymphadenopathy: its pathologic aspects.

PubMed

Buchino, J J; Byrd, R P; Kmetz, D R

1982-01-01

Sinus histiocytosis with massive lymphadenopathy (SHML) is generally regarded as a benign, self-limited, pseudolymphomatous process requiring little or no therapy. We studied a 13-year-old black boy with a ten-year clinical course of SHML that had varying, intermittent sites of extranodal involvement, including bone, submandibular gland, trachea, eye, and spinal cord. At the time of death, which was attributed to SHML, additional extranodal sites of involvement included thymus, kidney, heart, liver, and base of brain. Microscopic examination of the SHML lesions at the time of autopsy revealed varying stages of development, from proliferation to involution. This case illustrates that SHML may involve multiple organ systems, can kill, and that histologic evaluation of disease activity at one site cannot be used as an indicator of activity at another.

Methodological proposal for the remediation of a site affected by phosphogypsum deposits

NASA Astrophysics Data System (ADS)

Martínez-Sanchez, M. J.; Perez-Sirvent, C.; Bolivar, J. P.; Garcia-Tenorio, R.

2012-04-01

The accumulation of phosphogysum (PY) produces a well known environmental problems. The proposals for the remediation of these sites require multidisciplinary and very specific studies. Since they cover large areas a sampling design specifically outlined for each case is necessary in order the contaminants, transfer pathways and particular processes can be correctly identified. In addition to a suitable sampling of the soil, aquatic medium and biota, appropriate studies of the space-temporal variations by means of control samples are required. Two different stages should be considered: 1.- Diagnostic stage This stage includes preliminary studies, identification of possible sources of radiosotopes, design of the appropriate sampling plan, hydrogeological study, characterization and study of the space-temporal variability of radioisotopes and other contaminants, as well as the risk assessement for health and ecosystems, that depends on the future use of the site. 2.- Remediation proposal stage It comprises the evaluation and comparison of the different procedures for the decontamination/remediation, including models experiments at the laboratory. To this respect, the preparation and detailed study of a small scale pilot project is a task of particular relevance. In this way the suitability of the remediating technology can be checked, and its performance optimized. These two stages allow a technically well-founded proposal to be presented to the Organisms or Institutions in charge of the problem and facilitate decision-making. It both stages be included in a social communication campaign in order the final proposal be accepted by stakeholders.

Data Used in Analyses of Trends, and Nutrient and Suspended-Sediment Loads for Streams in the Southeastern United States, 1973-2005

USGS Publications Warehouse

Staub, Erik L.; Peak, Kelly L.; Tighe, Kirsten C.; Sadorf, Eric M.; Harned, Douglas A.

2010-01-01

Water-quality data from selected surface-water monitoring sites in the Southeastern United States were assessed for trends in concentrations of nutrients, suspended sediment, and major constituents and for in-stream nutrient and suspended-sediment loads for the period 1973-2005. The area of interest includes river basins draining into the southern Atlantic Ocean, the Gulf of Mexico, and the Tennessee River-drainage basins in Hydrologic Regions 03 (South Atlantic - Gulf) and 06 (Tennessee). This data assessment is related to studies of several major river basins as part of the U.S. Geological Survey National Water-Quality Assessment Program, which was designed to assess national water-quality trends during a common time period (1993-2004). Included in this report are data on which trend tests could be performed from 44 U.S. Geological Survey National Water Information System (NWIS) sampling sites. The constituents examined include major ions, nutrients, and suspended sediment; the physical properties examined include pH, specific conductance, dissolved oxygen, and streamflow. Also included are data that were tested for trends from an additional 290 sites from the U.S. Environmental Protection Agency Storage and Retrieval (STORET) database. The trend analyses of the STORET data were limited to total nitrogen and total phosphorus concentrations. Data from 48 U.S. Geological Survey NWIS sampling sites with sufficient water-quality and continuous streamflow data for estimating nutrient and sediment loads are included. The methods of data compilation and modification used prior to performing trend tests and load estimation are described. Results of the seasonal Kendall trend test and the Tobit trend test are given for the 334 monitoring sites, and in-stream load estimates are given for the 48 monitoring sites. Basin characteristics are provided, including regional landscape variables and agricultural nutrient sources (annual variations in cropping and fertilizer use). The data and results presented in this report are in tabular format and can be downloaded and used by environmental researchers and water managers, particularly in the Southeast.

Efficacy of exclosures in conserving local shrub biodiversity in xeric sandy grassland, Inner Mongolia, China

Treesearch

Feng-Rui Li; Zhi-Yu Zhou; Li-Ya Zhao; Ai-Sheng Zhang; Ling-Fen Kang

2007-01-01

This study investigated the abundance and frequency of occurrence of all shrub species present in the standing vegetation at four sites, including a 5-year exclosure (protected grassland) and three adjacent unprotected grazing sites that had been subjected to different levels of degradation (light, moderate and severe), in xeric sandy grassland of Inner Mongolia for...

Promising Practices in Using the Internet to Teach Social Studies

ERIC Educational Resources Information Center

Risinger, C. Frederick

2006-01-01

This article presents several teachers and school Web sites that offer teaching strategies in using the Internet to teach social sciences. These Web sites include: (1) Mrs. Cori Culp's Website (www.bv229.k12.ks.us/bvw_culp); (2) Mr. Williams's 5th Grade(teachers.santee.k12.ca.us/cwilliams/index.htm); (3) Ms. Stewart's Classroom Page…

Effects of post-harvest treatments on high-elevation forests in the North Cascade Range, Washington.

Treesearch

Ella Elman; David L. Peterson

2005-01-01

We studied the effects of post-harvest treatments on regeneration and forest composition 13-27 years following harvest in high-elevation forests of the North Cascade Range, Washington. Eighteen sites encompassing three common post-harvest treatments were examined at elevations ranging from 830 m to 1460 m. Treatments included: (1) sites broadcast burned and planted...

Developing a typology for understanding VFR as a primary purpose vs. VFR as a type of accommodation

Treesearch

Lori Pennington-Gray; Charles W. Lane; Andrew Holdnak

2003-01-01

This study examined VFR travelers in relation to their behaviors. Data were collected at fourteen sites Alachua County, Florida in 2001. Some of the sites included: hotels, local attractions and special events. A fixed choice questionnaire contained items asking about mode of transportation, demographic characteristics, number of people in the travel party, number of...

Improvement Strategies at Six Culturally Different Schools. Final Report FY91-FY95, Leadership for Change Project.

ERIC Educational Resources Information Center

Fuentes, Nancy; And Others

School leaders have begun to understand that "change is a process." Leaders must facilitate change, not merely disseminate or direct it. This publication presents findings of the Leadership for Change Project (LFC). The LFC studied six sites at different stages of the school-improvement process, including two "developmental" sites in Arkansas and…

How Are School Leaders and Teachers Allocating Their Time in the Intensive Partnership Sites? Working Paper WR-1041-1-BMGF

ERIC Educational Resources Information Center

Chambers, Jay; de los Reyes, Iliana Brodziak; Wang, Antonia; O'Neil, Caitlin

2014-01-01

The goal of the Intensive Partnership (IP) initiative is to improve student success by transforming how teachers are recruited, developed, assigned, rewarded, and retained. RAND and American Institutes for Research (AIR) have been studying the seven IP sites (including three districts and four charter management organizations--CMOs) since the…

Accessibility Trends among Academic Library and Library School Web Sites in the USA and Canada

ERIC Educational Resources Information Center

Schmetzke, Axel; Comeaux, David

2009-01-01

This paper focuses on the accessibility of North American library and library school Web sites for all users, including those with disabilities. Web accessibility data collected in 2006 are compared to those of 2000 and 2002. The findings of this follow-up study continue to give cause for concern: Despite improvements since 2002, library and…

Does a University Teacher Need to Change e-Learning Beliefs and Practices When Using a Social Networking Site? A Longitudinal Case Study

ERIC Educational Resources Information Center

Scott, Karen M.

2013-01-01

While much of the e-learning development at universities in the past 15 years has been on institutionally supported Learning Management Systems (LMSs), alternative educational technologies are being taken up following the rapid growth in emerging technologies, including social networking sites (SNSs). While teachers may choose educational…

A Study of How Young Adults Leverage Multiple Profile Management Functionality in Managing Their Online Reputation on Social Networking Sites

ERIC Educational Resources Information Center

McCune, T. John

2017-01-01

With privacy settings on social networking sites (SNS) perceived as complex and difficult to use and maintain, young adults can be left vulnerable to others accessing and using their personal information. Consequences of not regulating the boundaries their information on SNS include the ability for current and future employers to make…

Guideline-conforming timing of invasive management in troponin-positive or high-risk ACS without persistent ST-segment elevation in German chest pain units. Urban university maximum care vs. rural regional primary care.

PubMed

Breuckmann, F; Remberg, F; Böse, D; Lichtenberg, M; Kümpers, P; Pavenstädt, H; Waltenberger, J; Fischer, D

2016-03-01

This study aimed to analyze guideline adherence in the timing of invasive management for myocardial infarction without persistent ST-segment elevation (NSTEMI) in two exemplary German centers, comparing an urban university maximum care facility and a rural regional primary care facility. All patients diagnosed as having NSTEMI during 2013 were retrospectively enrolled in two centers: (1) site I, a maximum care center in an urban university setting, and (b) site II, a primary care center in a rural regional care setting. Data acquisition included time intervals from admission to invasive management, risk criteria, rate of intervention, and medical therapy. The median time from admission to coronary angiography was 12.0 h (site I) or 17.5 h (site II; p = 0.17). Guideline-adherent timing was achieved in 88.1 % (site I) or 82.9 % (site II; p = 0.18) of cases. Intervention rates were high in both sites (site I-75.5 % vs. site II-75.3 %; p = 0.85). Adherence to recommendations of medical therapy was high and comparable between the two sites. In NSTEMI or high-risk acute coronary syndromes without persistent ST-segment elevation, guideline-adherent timing of invasive management was achieved in about 85 % of cases, and was comparable between urban maximum and rural primary care settings. Validation by the German Chest Pain Unit Registry including outcome analysis is required.

Executive summary: Weldon Spring Site Environmental Report for calendar year 1992. Weldon Spring Site Remedial Action Project, Weldon Spring, Missouri

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-06-01

This report has been prepared to provide information about the public safety and environmental protection programs conducted by the Weldon Spring Site Remedial Action Project. The Weldon Spring site is located in southern St. Charles County, Missouri, approximately 48 km (30 mi) west of St. Louis. The site consists of two main areas, the Weldon Spring Chemical Plant and raffinate pits and the Weldon Spring Quarry. The objectives of the Site Environmental Report are to present a summary of data from the environmental monitoring program, to characterize trends and environmental conditions at the site, and to confirm compliance with environmentalmore » and health protection standards and requirements. The report also presents the status of remedial activities and the results of monitoring these activities to assess their impacts on the public and environment. The scope of the environmental monitoring program at the Weldon Spring site has changed since it was initiated. Previously, the program focused on investigations of the extent and level of contaminants in the groundwater, surface waters, buildings, and air at the site. In 1992, the level of remedial activities required monitoring for potential impacts of those activities, particularly on surface water runoff and airborne effluents. This report includes monitoring data from routine radiological and nonradiological sampling activities. These data include estimates of dose to the public from the Weldon Spring site; estimates of effluent releases; and trends in groundwater contaminant levels. Also, applicable compliance requirements, quality assurance programs, and special studies conducted in 1992 to support environmental protection programs are reviewed.« less

Bibliography of reports on studies of the geology, hydrogeology and hydrology at the Nevada Test Site, Nye County, Nevada, from 1951--1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seaber, P.R.; Stowers, E.D.; Pearl, R.H.

1997-04-01

The Nevada Test Site (NTS) was established in 1951 as a proving ground for nuclear weapons. The site had formerly been part of an Air Force bombing and gunnery range during World War II. Sponsor-directed studies of the geology, hydrogeology, and hydrology of the NTS began about 1956 and were broad based in nature, but were related mainly to the effects of the detonation of nuclear weapons. These effects included recommending acceptable media and areas for underground tests, the possibility of off-site contamination of groundwater, air blast and surface contamination in the event of venting, ground-shock damage that could resultmore » from underground blasts, and studies in support of drilling and emplacement. The studies were both of a pure scientific nature and of a practical applied nature. The NTS was the site of 828 underground nuclear tests and 100 above-ground tests conducted between 1951 and 1992 (U.S. Department of Energy, 1994a). After July 1962, all nuclear tests conducted in the United States were underground, most of them at the NTS. The first contained underground nuclear explosion was detonated on September 19, 1957, following extensive study of the underground effect of chemical explosives. The tests were performed by U.S. Department of Energy (DOE) and its predecessors, the U.S. Atomic Energy Commission and the Energy Research and Development Administration. As part of a nationwide complex for nuclear weapons design, testing and manufacturing, the NTS was the location for continental testing of new and stockpiled nuclear devices. Other tests, including Project {open_quotes}Plowshare{close_quotes} experiments to test the peaceful application of nuclear explosives, were conducted on several parts of the site. In addition, the Defense Nuclear Agency tested the effect of nuclear detonations on military hardware.« less

Technical Report Series on the Boreal Ecosystem-Atmosphere Study (BOREAS) RSS-19 1994 CASI At-Sensor Radiance and Reflectance Images

NASA Technical Reports Server (NTRS)

Miller, John; Freemantle, Jim; Nickeson, Jaime (Editor); Hall, Forrest G. (Editor); Smith, David E. (Technical Monitor)

2000-01-01

The Remote Sensing Science (RSS)-19 team collected Compact Airborne Spectrographic Imager (CASI) images from the Chieftain Navaho aircraft in order to observe the seasonal change in the radiometric reflectance properties of the boreal forest landscape. CASI was deployed as a site-specific optical sensor during Boreal Ecosystem-Atmosphere Study (BOREAS) field campaigns. Image data were collected with CASI on 36 days during five field campaigns between February and September 1994, primarily at flux tower sites located at study sites near Thompson, Manitoba, and Prince Albert, Saskatchewan. A variety of CASI data collection strategies were used to meet the following scientific objectives: 1) canopy bidirectional reflectance, 2) canopy biochemistry, 3) spatial variability, and 4) estimates of up and downwelling Photosynthetically Active Radiation (PAR) and spectral albedo, as well as changes along transects across lakes and transects the Northern Study Area (NSA) and Southern Study Area (SSA). The images are stored as binary image files. A subset of the 1994 CASI acquisitions have been compressed and included on the BOREAS CD-ROM set. This subset includes three images for the NSA-OBS (Old Black Spruce) site on 06 Jun 94, 08 Aug 94, and 06 Sep 94, one image for the SSA-OBS site on 24 Jul 94; and one image for the NSA-Fen site on 08 Aug 94. The CASI imagery on the BOREAS CD-ROMs have been compressed using the Gzip program. The rest of the 1994 BOREAS CASI archive are not contained on the BOREAS CD-ROM set. Inventory listing files are supplied on the CD-ROM to inform users of the data that were collected. The RSS-19 1994 CASI images are available from the Earth Observing System Data and Information System (EOSDIS) Oak Ridge National Laboratory (ORNL) Distributed Active Archive Center (DAAC). The data files are available on a CD-ROM (see document number 20010000884).

Spectroscopic Studies of Perturbed T1 Cu Sites in the Multicopper Oxidases Saccharomyces Cerevisiae Fet3p And Rhus Vernicifera Laccase: Allosteric Coupling Between the T1 And Trinuclear Cu Sites

DOE Office of Scientific and Technical Information (OSTI.GOV)

Augustine, A.J.; Kragh, M.E.; Sarangi, R.

2009-04-30

The multicopper oxidases catalyze the 4e{sup -} reduction of O{sub 2} to H{sub 2}O coupled to the 1e{sup -} oxidation of 4 equiv of substrate. This activity requires four Cu atoms, including T1, T2, and coupled binuclear T3 sites. The T2 and T3 sites form a trinuclear cluster (TNC) where O{sub 2} is reduced. The T1 is coupled to the TNC through a T1-Cys-His-T3 electron transfer (ET) pathway. In this study the two T3 Cu coordinating His residues which lie in this pathway in Fet3 have been mutated, H483Q, H483C, H485Q, and H485C, to study how perturbation at the TNCmore » impacts the T1 Cu site. Spectroscopic methods, in particular resonance Raman (rR), show that the change from His to Gln to Cys increases the covalency of the T1 Cu?S Cys bond and decreases its redox potential. This study of T1?TNC interactions is then extended to Rhus vernicifera laccase where a number of well-defined species including the catalytically relevant native intermediate (NI) can be trapped for spectroscopic study. The T1 Cu?S covalency and potential do not change in these species relative to resting oxidized enzyme, but interestingly the differences in the structure of the TNC in these species do lead to changes in the T1 Cu rR spectrum. This helps to confirm that vibrations in the cysteine side chain of the T1 Cu site and the protein backbone couple to the Cu?S vibration. These changes in the side chain and backbone provide a possible mechanism for regulating intramolecular T1 to TNC ET in NI and partially reduced enzyme forms for efficient turnover.« less

Post-operative shampoo effects in neurosurgical patients: a pilot experimental study.

PubMed

Palese, Alvisa; Moreale, Renzo; Noacco, Massimo; Pistrino, Flavia; Mastrolia, Irene; Sartor, Assunta; Scarparo, Claudio; Skrap, Miran

2015-04-01

Neurosurgical site infections are an important issue. Among the acknowledged preventive tactics, the non-shaving technique is well established in the neurosurgical setting. However, given that patient's hair around the surgical site may retain biologic material that emerges during the surgical procedure or that may simply become dirty, which may increase the risk of surgical site infections, if and when shampooing should be offered remains under debate. A pilot experimental study was undertaken from 2011 to 2012. A series of neurosurgical patients not affected by conditions that would increase the risk of post-operative infection were assigned randomly to the exposed group (receiving shampoo 72 h after surgical procedure) or control group (receiving standard dressing surveillance without shampooing). Comfort, surgical site contamination (measured as the number of colony-forming units [CFU]), and SSIs at 30 d after surgery were the main study outcomes. A total of 53 patients were included: 25 (47.2%) received a shampoo after 72 h whereas 28 (52.8%) received standard care. Patients who received a shampoo reported a similar level of comfort (average=8.04; standard deviation [SD] 1.05) compared with those receiving standard care (average 7.3; SD 3.2) although this was not statistically significant (p=0.345). No statistically significant difference emerged in the occurrence of surgical site contamination between the groups, and no SSIs were detected within 30 d. In our pilot study, the results of which are not generalizable because of the limited sample of patients involved, a gentle shampoo offered 72 h after the surgical procedure did not increase the SSIs occurrence or the contamination of the surgical site, although it may increase the perception of comfort by patients. Further studies are strongly recommended involving a larger sample size and designed to include more diversified neurosurgical patients undergoing surgical procedures in different centers.

Seed Rain and Seed Bank Reveal that Seed Limitation Strongly Influences Plant Community Assembly in Grasslands

PubMed Central

Marteinsdóttir, Bryndís

2014-01-01

Dispersal is an important factor in plant community assembly, but assembly studies seldom include information on actual dispersal into communities, i.e. the local propagule pool. The aim of this study was to determine which factors influence plant community assembly by focusing on two phases of the assembly process: the dispersal phase and the establishment phase. At 12 study sites in grazed ex-arable fields in Sweden the local plant community was determined and in a 100-m radius around the centre of each site, the regional species pool was measured. The local seed bank and the seed rain was explored to estimate the local propagule pool. Trait-based models were then applied to investigate if species traits (height, seed mass, clonal abilities, specific leaf area and dispersal method) and regional abundance influenced which species from the regional species pool, dispersed to the local community (dispersal phase) and which established (establishment phase). Filtering of species during the dispersal phase indicates the effect of seed limitation while filtering during the establishment phase indicates microsite limitation. On average 36% of the regional species pool dispersed to the local sites and of those 78% did establish. Species with enhanced dispersal abilities, e.g. higher regional abundance, smaller seeds and dispersed by cattle, were more likely to disperse to the sites than other species. At half the sites, dispersal was influenced by species height. Species establishment was however mainly unlinked to the traits included in this study. This study underlines the importance of seed limitation in local plant community assembly. It also suggests that without information on species dispersal into a site, it is difficult to distinguish between the influence of dispersal and establishment abilities, and thus seed and microsite limitation, as both can be linked to the same trait. PMID:25057815

Increasing Efficiency of Recruitment in Early Parkinson's Disease Trials: A Case Study Examination of the STEADY-PD III Trial.

PubMed

Berk, Sarah; Greco, Brittany L; Biglan, Kevin; Kopil, Catherine M; Holloway, Robert G; Meunier, Claire; Simuni, Tanya

2017-01-01

Challenges in clinical trial recruitment threaten the successful development of improved therapies. This is particularly true in Parkinson's disease (PD) studies of disease modification where the population of interest is difficult to find and study design is more complex. This paper seeks to understand how STEADY PD III, a National Institute of Neurological Disorders and Stroke (NINDS) funded phase 3 trial evaluating the efficacy of isradipine as a disease modifying agent for PD, was able to recruit their full target population 6 months ahead of schedule. STEADY PD III aimed to enroll 336 individuals with early stage idiopathic PD within 18 months using 57 sites across the United States and Canada. The study included a 10% NIH minority recruitment goal. Eligible participants agreed to be followed for up to 36 months, complete 12 in-person visits and 4 telephone visits. A Recruitment Committee of key stakeholders was critical in the development of a comprehensive recruitment strategy involving: multi-modal outreach, protocol modifications and comprehensive site selection and activation. Efforts to increase site-specific minority recruitment strategies were encouraged through additional funding. A total of 336 individuals, including 34 minorities, were enrolled within 12 months - 6 months ahead of the projected timeline. Quantitative analysis of recruitment activity questionnaires found that of the sites that completed them (n = 54), (20.4%) met goals, (24.1%) exceeded goals, and (55.6%) fell below projected goals. Referral sources completed at time of screening indicate top four study referral sources as: site personnel (53.8%); neurologists (24%); Fox Trial Finder (10.2%); and communications from The Michael J. Fox Foundation (3.9%). STEADY PD III serves as an important example of methods that can be used to increase clinical trial recruitment. This research highlights a continued need to improve site infrastructure and dedicate more resources to increased participation of minorities in clinical research.

Increasing Efficiency of Recruitment in Early Parkinson’s Disease Trials: A Case Study Examination of the STEADY-PD III Trial

PubMed Central

Berk, Sarah; Greco, Brittany L.; Biglan, Kevin; Kopil, Catherine M.; Holloway, Robert G.; Meunier, Claire; Simuni, Tanya

2017-01-01

Background: Challenges in clinical trial recruitment threaten the successful development of improved therapies. This is particularly true in Parkinson’s disease (PD) studies of disease modification where the population of interest is difficult to find and study design is more complex. Objective: This paper seeks to understand how STEADY PD III, a National Institute of Neurological Disorders and Stroke (NINDS) funded phase 3 trial evaluating the efficacy of isradipine as a disease modifying agent for PD, was able to recruit their full target population 6 months ahead of schedule. Methods: STEADY PD III aimed to enroll 336 individuals with early stage idiopathic PD within 18 months using 57 sites across the United States and Canada. The study included a 10% NIH minority recruitment goal. Eligible participants agreed to be followed for up to 36 months, complete 12 in-person visits and 4 telephone visits. A Recruitment Committee of key stakeholders was critical in the development of a comprehensive recruitment strategy involving: multi-modal outreach, protocol modifications and comprehensive site selection and activation. Efforts to increase site-specific minority recruitment strategies were encouraged through additional funding. Results: A total of 336 individuals, including 34 minorities, were enrolled within 12 months – 6 months ahead of the projected timeline. Quantitative analysis of recruitment activity questionnaires found that of the sites that completed them (n = 54), (20.4%) met goals, (24.1%) exceeded goals, and (55.6%) fell below projected goals. Referral sources completed at time of screening indicate top four study referral sources as: site personnel (53.8%); neurologists (24%); Fox Trial Finder (10.2%); and communications from The Michael J. Fox Foundation (3.9%). Conclusions: STEADY PD III serves as an important example of methods that can be used to increase clinical trial recruitment. This research highlights a continued need to improve site infrastructure and dedicate more resources to increased participation of minorities in clinical research. PMID:29103052

Crustal dynamics project data analysis, 1987. Volume 1: Fixed station VLBI geodetic results, 1979-1986

NASA Technical Reports Server (NTRS)

Ryan, J. W.; Ma, C.

1987-01-01

The Goddard VLBI group reports the results of analyzing Mark III data sets from fixed observatories through the end of 1986 and available to the Crustal Dynamics Project. All full-day data from POLARIS/IRIS are included. The mobile VLBI sites at Platteville (Colorado), Penticton (British Columbia), and Yellowknife (Northwest Territories) are also included since these occupations bear on the study of plate stability. Two large solutions, GLB121 and GLB122, were used to obtain Earth rotation parameters and baseline evolutions, respectively. Radio source positions were estimated globally while nutation offsets were estimated from each data set. The results include 25 sites and 108 baselines.

Southeast Asian Summer Burning: A Micro Pulse Lidar Network Study of Aerosol Particle Physical Properties near Fires in Borneo and Sumatra

NASA Astrophysics Data System (ADS)

Lolli, S.; Welton, E. J.; Holben, B. N.; Campbell, J. R.

2013-12-01

In August and September 2012, as part of the continuing Seven South East Asian Studies (7-SEAS) project, three autonomous elastic-scattering 355 nm lidars were deployed by the NASA Micro Pulse Lidar Network (MPLNET) to Sumatra and Borneo, measuring the vertical profile of aerosol particle scattering during peak burning season. In coordination with the Aerosol Robotic Network (AERONET), a regional characterization of aerosol particle physical properties and distribution was performed. In addition to a permanent regional network site at Singapore, the three temporary sites established for this research include Jambi (Sumatra, Indonesia), Kuching (northwest Borneo, Malaysia) and Palangkaraya (south-central Borneo, Indonesia). In this paper, we discuss the mission and instruments, and introduce data products available to the community through the MPLNET online website. We further describe initial results of the study, including a contrast of mean vertical scattering profiles versus those observed near active fire sources at Jambi and Palangkaraya, and resolve longer-range particle evolution at receptor sites, like Kuching, that are most commonly 1-2 days downwind of larger fire complexes.

Nuclear event time histories and computed site transfer functions for locations in the Los Angeles region

USGS Publications Warehouse

Rogers, A.M.; Covington, P.A.; Park, R.B.; Borcherdt, R.D.; Perkins, D.M.

1980-01-01

This report presents a collection of Nevada Test Site (NTS) nuclear explosion recordings obtained at sites in the greater Los Angeles, Calif., region. The report includes ground velocity time histories, as well as, derived site transfer functions. These data have been collected as part of a study to evaluate the validity of using low-level ground motions to predict the frequency-dependent response of a site during an earthquake. For this study 19 nuclear events were recorded at 98 separate locations. Some of these sites have recorded more than one of the nuclear explosions, and, consequently, there are a total of 159, three-component station records. The location of all the recording sites are shown in figures 1–5, the station coordinates and abbreviations are given in table 1. The station addresses are listed in table 2, and the nuclear explosions that were recorded are listed in table 3. The recording sites were chosen on the basis of three criteria: (1) that the underlying geological conditions were representative of conditions over significant areas of the region, (2) that the site was the location of a strong-motion recording of the 1971 San Fernando earthquake, or (3) that more complete geographical coverage was required in that location.

Search for Mars lander/rover/sample-return sites: A status review

NASA Technical Reports Server (NTRS)

Masursky, Harold; Dial, A. L., Jr.; Morris, E. C.; Strobell, M. E.; Applebee, D. J.; Chapman, M. G.

1988-01-01

Ten Mars sites were studied in the USA for four years. The sites are the Chasma Boreale (North Pole), Planum Australe (South Pole), Olympus Rupes, Mangala Valles, Memnonia Sulci, Candor Chasma, Kasel Valles, Nilosyrtis Mensae, Elysium Montes, and Apollinaris Patera. Seven sites are being studied by the USSR; their prime sites are located at the east mouth of Kasel Valles and near Uranius Patera. Thirteen geological maps of the first six USA sites are compiled and in review. Maps of the Mangala East and West sites at 1:1/2 million scale and a 1:2 million scale map show evidence of three episodes of small-channel formation interspersed with episodes of volcanism and tectonism that span the period from 3.5 to 0.6 b.y. ago. The tectonic and geological history of Mars, both ancient and modern, can be elucidated by sampling volcanic and fluvial geologic units at equatorial sites and layered deposits at polar sites. The evidence appears clear for multiple episodes of fluvial channeling, including some that are quite recent; this evidence contrasts with the theses of Baker and Partridge (1986) and many others that all channels are ancient. Verification of this hypothesis by Mars Observer will be an important step forward in the perception of the history of Mars.

Probing the emitter site of Renilla luciferase using small organic molecules; an attempt to understand the molecular architecture of the emitter site.

PubMed

Salehi, Farajollah; Emamzadeh, Rahman; Nazari, Mahboobeh; Rasa, Seyed Mohammad Mahdi

2016-12-01

Renilla luciferase is a sensitive enzyme and has wide applications in biotechnology such as drug screening. Previous studies have tried to show the catalytic residues, nevertheless, the accurate architecture and molecular behavior of its emitter site remains uncharacterized. In this study, the activity of Renilla luciferase, in the presence of two small organic molecules including dimethyl sulfoxide (DMSO) and isopropanol was considered and the structure was studied by circular dichroism (CD) and fluorescence spectroscopy. Moreover, the interaction of small organic molecules with the Renilla luciferase was studied using molecular dynamics simulations. Kinetics studies showed that at low concentration of DMSO (16.6-66mM) and isopropanol (19.3-76mM) the K m changed and a competitive inhibition pattern was observed. Moreover, spectroscopy studies reveled that the changes of activity of Renilla luciferase in the presence of low concentrations of small organic molecules was not associated with structural collapse or severe changes in the enzyme conformation. Molecular dynamics simulations indicated that DMSO and isopropanol, as probing molecules, were both able to bind to the emitter site and remained with the residues of the emitter site. Based on the probing data, the architecture of the emitter site in the "non-binding" model was proposed. Copyright © 2016 Elsevier B.V. All rights reserved.

Association between site-specific bone mineral density and glucose homeostasis and anthropometric traits in healthy men and women.

PubMed

Kim, Se-Min; Cui, Jinrui; Rhyu, Jane; Guo, Xiuqing; Chen, Yii-Der I; Hsueh, Willa A; Rotter, Jerome I; Goodarzi, Mark O

2018-06-01

Patients with type 2 diabetes mellitus have an increased risk of fracture despite normal or increased bone mineral density (BMD). Studies on the relationship of glucose homeostasis with BMD phenotypes have been inconclusive because distinguishing the roles of insulin resistance and hyperglycaemia in bone remodelling is challenging. In this study, we sought to define the relationship of site-specific BMD with glucose homeostasis traits and anthropometric traits. In a cross-sectional study, we examined 787 subjects from the Mexican-American Coronary Artery Disease (MACAD) cohort who had undergone euglycaemic-hyperinsulinaemic clamps, oral glucose tolerance testing and dual X-ray absorptiometry. Glucose homeostasis traits included insulinogenic index (IGI30), insulin sensitivity (M value), insulin clearance (MCRI), fasting insulin, fasting glucose and 2-hour glucose. Univariate and multivariate analyses were performed to assess the association of glucose homeostasis and anthropometric traits with site-specific BMD. Two-hour glucose was negatively associated with arm BMD in women, which remained significant in multivariate analysis (β = -.15, P = .0015). Positive correlations between fasting insulin and BMD at weight-bearing sites, including pelvis (β = .22, P < .0001) and legs (β = .17, P = .001) in women and pelvis (β = .33, P < .0001) in men, lost significance after multivariate adjustment. Lean mass exhibited strong independent positive associations with BMD at multiple sites in both sexes. Our findings suggest that (i) anabolic effects of insulin might work via mechanical loading from lean mass; (ii) a direct negative effect of increasing glucose might be more prominent at cortical-bone-rich sites in women; and (iii) lean mass is a strong positive predictor of bone mass. © 2018 John Wiley & Sons Ltd.

A forestry GIS-based study on evaluating the potential of imaging spectroscopy in mapping forest land fertility

NASA Astrophysics Data System (ADS)

Mõttus, Matti; Takala, Tuure

2014-12-01

Fertility, or the availability of nutrients and water, controls forest productivity. It affects its carbon sequestration, and thus the forest's effect on climate, as well as its commercial value. Although the availability of nutrients cannot be measured directly using remote sensing methods, fertility alters several vegetation traits detectable from the reflectance spectra of the forest stand, including its pigment content and water stress. However, forest reflectance is also influenced by other factors, such as species composition and stand age. Here, we present a case study demonstrating how data obtained using imaging spectroscopy is correlated with site fertility. The study was carried out in Hyytiälä, Finland, in the southern boreal forest zone. We used a database of state-owned forest stands including basic forestry variables and a site fertility index. To test the suitability of imaging spectroscopy with different spatial and spectral resolutions for site fertility mapping, we performed two airborne acquisitions using different sensor configurations. First, the sensor was flown at a high altitude with high spectral resolution resulting in a pixel size in the order of a tree crown. Next, the same area was flown to provide reflectance data with sub-meter spatial resolution. However, to maintain usable signal-to-noise ratios, several spectral channels inside the sensor were combined, thus reducing spectral resolution. We correlated a number of narrowband vegetation indices (describing canopy biochemical composition, structure, and photosynthetic activity) on site fertility. Overall, site fertility had a significant influence on the vegetation indices but the strength of the correlation depended on dominant species. We found that high spatial resolution data calculated from the spectra of sunlit parts of tree crowns had the strongest correlation with site fertility.

Design and implementation of an identification system in construction site safety for proactive accident prevention.

PubMed

Yang, Huanjia; Chew, David A S; Wu, Weiwei; Zhou, Zhipeng; Li, Qiming

2012-09-01

Identifying accident precursors using real-time identity information has great potential to improve safety performance in construction industry, which is still suffering from day to day records of accident fatality and injury. Based on the requirements analysis for identifying precursor and the discussion of enabling technology solutions for acquiring and sharing real-time automatic identification information on construction site, this paper proposes an identification system design for proactive accident prevention to improve construction site safety. Firstly, a case study is conducted to analyze the automatic identification requirements for identifying accident precursors in construction site. Results show that it mainly consists of three aspects, namely access control, training and inspection information and operation authority. The system is then designed to fulfill these requirements based on ZigBee enabled wireless sensor network (WSN), radio frequency identification (RFID) technology and an integrated ZigBee RFID sensor network structure. At the same time, an information database is also designed and implemented, which includes 15 tables, 54 queries and several reports and forms. In the end, a demonstration system based on the proposed system design is developed as a proof of concept prototype. The contributions of this study include the requirement analysis and technical design of a real-time identity information tracking solution for proactive accident prevention on construction sites. The technical solution proposed in this paper has a significant importance in improving safety performance on construction sites. Moreover, this study can serve as a reference design for future system integrations where more functions, such as environment monitoring and location tracking, can be added. Copyright © 2011 Elsevier Ltd. All rights reserved.

Combined measurement and modeling of the hydrological impact of hydraulic redistribution using CLM4.5 at eight AmeriFlux sites

NASA Astrophysics Data System (ADS)

Fu, Congsheng; Wang, Guiling; Goulden, Michael L.; Scott, Russell L.; Bible, Kenneth; Cardon, Zoe G.

2016-05-01

Effects of hydraulic redistribution (HR) on hydrological, biogeochemical, and ecological processes have been demonstrated in the field, but the current generation of standard earth system models does not include a representation of HR. Though recent studies have examined the effect of incorporating HR into land surface models, few (if any) have done cross-site comparisons for contrasting climate regimes and multiple vegetation types via the integration of measurement and modeling. Here, we incorporated the HR scheme of Ryel et al. (2002) into the NCAR Community Land Model Version 4.5 (CLM4.5), and examined the ability of the resulting hybrid model to capture the magnitude of HR flux and/or soil moisture dynamics from which HR can be directly inferred, to assess the impact of HR on land surface water and energy budgets, and to explore how the impact may depend on climate regimes and vegetation conditions. Eight AmeriFlux sites with contrasting climate regimes and multiple vegetation types were studied, including the Wind River Crane site in Washington State, the Santa Rita Mesquite savanna site in southern Arizona, and six sites along the Southern California Climate Gradient. HR flux, evapotranspiration (ET), and soil moisture were properly simulated in the present study, even in the face of various uncertainties. Our cross-ecosystem comparison showed that the timing, magnitude, and direction (upward or downward) of HR vary across ecosystems, and incorporation of HR into CLM4.5 improved the model-measurement matches of evapotranspiration, Bowen ratio, and soil moisture particularly during dry seasons. Our results also reveal that HR has important hydrological impact in ecosystems that have a pronounced dry season but are not overall so dry that sparse vegetation and very low soil moisture limit HR.

Multi-site study of diffusion metric variability: effects of site, vendor, field strength, and echo time on regions-of-interest and histogram-bin analyses.

PubMed

Helmer, K G; Chou, M-C; Preciado, R I; Gimi, B; Rollins, N K; Song, A; Turner, J; Mori, S

2016-02-27

It is now common for magnetic-resonance-imaging (MRI) based multi-site trials to include diffusion-weighted imaging (DWI) as part of the protocol. It is also common for these sites to possess MR scanners of different manufacturers, different software and hardware, and different software licenses. These differences mean that scanners may not be able to acquire data with the same number of gradient amplitude values and number of available gradient directions. Variability can also occur in achievable b-values and minimum echo times. The challenge of a multi-site study then, is to create a common protocol by understanding and then minimizing the effects of scanner variability and identifying reliable and accurate diffusion metrics. This study describes the effect of site, scanner vendor, field strength, and TE on two diffusion metrics: the first moment of the diffusion tensor field (mean diffusivity, MD), and the fractional anisotropy (FA) using two common analyses (region-of-interest and mean-bin value of whole brain histograms). The goal of the study was to identify sources of variability in diffusion-sensitized imaging and their influence on commonly reported metrics. The results demonstrate that the site, vendor, field strength, and echo time all contribute to variability in FA and MD, though to different extent. We conclude that characterization of the variability of DTI metrics due to site, vendor, field strength, and echo time is a worthwhile step in the construction of multi-center trials.

Mesoscale carbon sequestration site screening and CCS infrastructure analysis.

PubMed

Keating, Gordon N; Middleton, Richard S; Stauffer, Philip H; Viswanathan, Hari S; Letellier, Bruce C; Pasqualini, Donatella; Pawar, Rajesh J; Wolfsberg, Andrew V

2011-01-01

We explore carbon capture and sequestration (CCS) at the meso-scale, a level of study between regional carbon accounting and highly detailed reservoir models for individual sites. We develop an approach to CO(2) sequestration site screening for industries or energy development policies that involves identification of appropriate sequestration basin, analysis of geologic formations, definition of surface sites, design of infrastructure, and analysis of CO(2) transport and storage costs. Our case study involves carbon management for potential oil shale development in the Piceance-Uinta Basin, CO and UT. This study uses new capabilities of the CO(2)-PENS model for site screening, including reservoir capacity, injectivity, and cost calculations for simple reservoirs at multiple sites. We couple this with a model of optimized source-sink-network infrastructure (SimCCS) to design pipeline networks and minimize CCS cost for a given industry or region. The CLEAR(uff) dynamical assessment model calculates the CO(2) source term for various oil production levels. Nine sites in a 13,300 km(2) area have the capacity to store 6.5 GtCO(2), corresponding to shale-oil production of 1.3 Mbbl/day for 50 years (about 1/4 of U.S. crude oil production). Our results highlight the complex, nonlinear relationship between the spatial deployment of CCS infrastructure and the oil-shale production rate.

77 FR 3499 - Sony Electronics, Inc., Including On-Site Leased Workers From Selectremedy Park Ridge, NJ...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-24

... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-71,501M] Sony Electronics, Inc... Electronics, Inc., SEL Headquarters, including on-site leased workers of SelectRemedy, StaffMark, and Payrolling.com , San Diego, California (TA-W-71,501); Sony Electronics, Inc., including on-site leased...

77 FR 44685 - ConocoPhillips Company, Trainer Refinery, Including On-Site Leased Workers From Shrack, Young...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-30

..., Trainer Refinery, Including On-Site Leased Workers From Shrack, Young, and Associates, Inc., and Project... applicable to workers and former workers of ConocoPhillips Company, Trainer Refinery, Trainer, Pennsylvania..., and heavy oil. The subject worker group includes on-site leased workers from Shrack, Young, and...

76 FR 66328 - Callaway Golf Ball Operations, Inc., Including On-Site Leased Workers From Reliable Temp Services...

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2011-10-26

... Operations, Inc., Including On-Site Leased Workers From Reliable Temp Services, Inc., Johnson & Hill Staffing... Golf Ball Operations, Inc., including on-site leased workers from Reliable Temp Services, Inc., and... Reliable Temp Services, Inc., Johnson & Hill Staffing and Apollo Security, Chicopee, Massachusetts, who...

75 FR 5147 - Acushnet Company a Subsidiary of Fortune Brands Including On-Site Leased Workers From Olsten...

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2010-02-01

...,763B] Acushnet Company a Subsidiary of Fortune Brands Including On-Site Leased Workers From Olsten Staffing Services Fairhaven, MA; Acushnet Company a Subsidiary of Fortune Brands Including On-Site Leased Workers From Olsten Staffing Services New Bedford, MA; Acushnet Company a Subsidiary of Fortune Brands...

75 FR 11913 - Chrysler, LLC; Warren Stamping Plant, Including On-Site Leased Workers From Caravan Knight...

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2010-03-12

... Stamping Plant, Including On-Site Leased Workers From Caravan Knight Facilities Management LLC; Warren, MI... from Caravan Knight Facilities Management LLC were employed on-site at the Warren, Michigan location of... Department is amending this certification to include workers leased from Caravan Knight Facilities Management...

76 FR 13226 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance

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2011-03-10

... BUILDER CABINET GROUP INCLUDING ON-SITE LEASED WORKERS FROM RESERVES NETWORK AND RELIABLE STAFFING WAVERLY, OHIO. TA-W-71,287B MASCO BUILDER CABINET GROUP INCLUDING ON-SITE LEASED WORKERS FROM RESERVES NETWORK... Builder Cabinet Group, including on-site leased workers from Reserves Network and Reliable Staffing...

36 CFR 64.6 - Application procedures.

Code of Federal Regulations, 2010 CFR

2010-07-01

... site including the type of development to be included in the project (if a site plan is available it... project will have any effect on a site in, or eligible for nomination to the National Register of Historic Places. The comments of the SHPO will be included with the application. (4) Flood Disaster Protection Act...

76 FR 22729 - Polaris Industries, Including On-Site Leased Workers From Westaff, Supply Technologies, Aerotek...

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2011-04-22

..., Including On-Site Leased Workers From Westaff, Supply Technologies, Aerotek, Securitas Security Services..., 2011 to include on-site leased workers from Supply Technologies, Aerotek and Securitas Security Services. The notice was published in the Federal Register on December 13, 2010 (75 FR 77666) and February...

75 FR 41523 - Paris Accessories, Inc., Including On-Site Leased Workers From Job Connections, New Smithville...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-16

... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-71,106; TA-W-71,106A] Paris Accessories, Inc., Including On-Site Leased Workers From Job Connections, New Smithville, PA; Paris... Paris Accessories, Inc., including on-site leased workers from Job Connections, New Smithville...

78 FR 15049 - The Evercare Company Including On-Site Leased Workers From Global Personnel Solutions and...

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2013-03-08

... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-81,932] The Evercare Company Including On-Site Leased Workers From Global Personnel Solutions and Manpower Waynesboro, Georgia; Amended... group included on-site leased workers from Global Personnel Solutions. In response to an inquiry by the...

78 FR 21155 - Eastman Kodak Company, IPS-Dayton Location, Including On-site Leased Workers From Adecco, Dayton...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-09

... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-81,387] Eastman Kodak Company, IPS--Dayton Location, Including On-site Leased Workers From Adecco, Dayton, Ohio; Notice of... and former workers of Eastman Kodak Company, IPS--Dayton Location, including on-site leased workers...