Open-Access Electronic Textbooks: An Overview

ERIC Educational Resources Information Center

Ovadia, Steven

2011-01-01

Given the challenging economic climate in the United States, many academics are looking to open-access electronic textbooks as a way to provide students with traditional textbook content at a more financially advantageous price. Open access refers to "the free and widely available information throughout the World Wide Web. Once an article's…

Representation of Scientific Methodology in Secondary Science Textbooks

ERIC Educational Resources Information Center

Binns, Ian C.; Bell, Randy L.

2015-01-01

This study explored how eight widely used secondary science textbooks described scientific methodology and to what degree the textbooks' examples and investigations were consistent with this description. Data consisted of all text from student and teacher editions that referred to scientific methodology and all investigations. Analysis used an…

How Texas Rewrote Your Textbooks.

ERIC Educational Resources Information Center

Moyer, Wayne A.

1985-01-01

Reviews issues and events related to adopting high school biology textbooks in Texas. Specific reference is given to the viewpoints of Mel and Norma Gabler. It is argued that factors controlling textbook content should not result from past market forces, but from a permanent science constituency and an informed public. (DH)

Seri Landscape Classification and Spatial Reference

ERIC Educational Resources Information Center

O'Meara, Carolyn

2010-01-01

This thesis contributes to the growing field of ethnophysiography, a new subfield of cognitive anthropology that aims to determine the universals and variation in the categorization of landscape objects across cultures. More specifically, this work looks at the case of the Seri people of Sonora, Mexico to investigate the way they categorize…

The Pedagogy of Fear and Guilt: How Textbooks Treat the World Economy.

ERIC Educational Resources Information Center

Newitt, Jane

1984-01-01

The central finding of a review of 63 high school history, geography, civics, and economics textbooks is that the textbooks are not accurately describing the world economy. For example, few of the texts refer to economic gains being made by many countries or mention the existence of middle income countries. (RM)

The Separation of Church and State. Exploring the Constitution Series.

ERIC Educational Resources Information Center

McWhirter, Darien A.

This textbook on the separation of church and state continues the "Exploring the Constitution Series," which introduces important areas of constitutional law. Intended to serve either as a reference work, a supplement to a standard textbook, or as the textbook for a course, this volume covers the constitutional issues of prayer in public…

Sociology of health textbooks and narratives: historical significance.

PubMed

Nunes, Everardo Duarte

2016-03-01

This article has as its starting point two central ideas: textbooks as a means of production and dissemination of knowledge and narrative as an approach. After a brief review of studies on health/medical sociology textbooks, I analyze a few of these textbooks from the 1900-2012 period, produced in the United States and England. I have selected eleven textbooks which I thought were representative. In addition to a content analysis, the textbooks are located within the process of constitution of the health/medical sociology with brief references to the biographies of the authors. The textbooks analyzed were classified according to the main narrative features: doctor-centered; interdisciplinary; pedagogical; analytical; almost autobiographical; critical; and synthetic-reflective. In the final remarks, some points about the textbooks, limits and possibilities are presented.

Data Processing (Advanced Business Programming) Volume II. Instructor's Guide.

ERIC Educational Resources Information Center

Litecky, Charles R.; Lamkin, Tim

This curriculum guide for an advanced course in data processing is for use as a companion publication to a textbook or textbooks; references to appropriate textbooks are given in most units. Student completion of assignments in Volume I, available separately (see ED 220 604), is a prerequisite. Topics covered in the 18 units are introduction,…

WikiTextbooks: Designing Your Course around a Collaborative Writing Project

ERIC Educational Resources Information Center

Katz, Brian P.; Thoren, Elizabeth

2014-01-01

We have used wiki technology to support large-scale, collaborative writing projects in which the students build reference texts (called WikiTextbooks). The goal of this paper is to prepare readers to adapt this idea for their own courses. We give examples of the implementation of WikiTextbooks in a variety of courses, including lecture and…

Observations on the Use of Textbooks in the Teaching of Principles of Economics.

ERIC Educational Resources Information Center

Boskin, Michael J.

1988-01-01

Discusses the role of the textbook in the principles of economics course. Recognizing that textbooks are only one source of input for students, and that they substitute for lectures to a limited extent, Boskin recommends that texts should stress the basics and serve as a reference source to support classroom instruction. (GEA)

Sex-Role Stereotyping in Mathematics Textbooks. Research Report.

ERIC Educational Resources Information Center

New Zealand Dept. of Education, Wellington.

This study looked at six primary textbooks and 25 of 31 secondary textbooks of mathematics published in New Zealand. All exercises, problems, and illustrations were analyzed for references to roles and activities assigned to males and females. The number of times males and females were mentioned and the number of famous people of each sex noted…

Nanomedicine concepts in the general medical curriculum: initiating a discussion

PubMed Central

Sweeney, Aldrin E

2015-01-01

Various applications of nanoscale science to the field of medicine have resulted in the ongoing development of the subfield of nanomedicine. Within the past several years, there has been a concurrent proliferation of academic journals, textbooks, and other professional literature addressing fundamental basic science research and seminal clinical developments in nanomedicine. Additionally, there is now broad consensus among medical researchers and practitioners that along with personalized medicine and regenerative medicine, nanomedicine is likely to revolutionize our definitions of what constitutes human disease and its treatment. In light of these developments, incorporation of key nanomedicine concepts into the general medical curriculum ought to be considered. Here, I offer for consideration five key nanomedicine concepts, along with suggestions regarding the manner in which they might be incorporated effectively into the general medical curriculum. Related curricular issues and implications for medical education also are presented. PMID:26677322

A Thorough Scrutiny of ELT Textbook Evaluations: A Review Inquiry

ERIC Educational Resources Information Center

Gholami, Reza; Noordin, Nooreen; Rafik-Galea, Shameem

2017-01-01

It is thoroughly agreed that English language textbooks stand amongst the foremost components in any language classrooms worldwide, being referred to as valid, beneficial and labor-saving tools to fulfill an extensive range of needs. An ELT textbook is not merely a set of sheets of paper fastened together to hinge at one side, but is the beating…

Characteristic research on Hong Kong "I learned" series computer textbooks

NASA Astrophysics Data System (ADS)

Hu, Jinyan; Liu, Zhongxia; Li, Yuanyuan; Lu, Jianheng; Zhang, Lili

2011-06-01

Currently, the construction of information technology textbooks in the primary and middle schools is an important content of the information technology curriculum reform. The article expect to have any inspire and reference on inland China school information technology teaching material construction and development through the analyzing and refining the characteristics of the Hong Kong quality textbook series - "I learn . elementary school computer cognitive curriculum".

A novel approach to comparing reproductive stage serum profiles in mares using near infrared spectroscopy (NIR) and aquaphotomics

USDA-ARS?s Scientific Manuscript database

The capability of near infrared spectroscopy (NIR) to detect biomolecules in aqueous solutions, a sub-field of NIR called Aquaphotomics, has yet to be fully explored. Aquaphotomics references water absorbance patterns and wavelength shifts in the 1st overtone of the water spectrum as they change pat...

Australian Applied Linguistics in Relation to International Trends

ERIC Educational Resources Information Center

Baldauf, Richard B., Jr.; Kaplan, Robert B.

2010-01-01

Applied Linguistics is a diverse field, comprising a substantial number of sub-fields, sub-specialisations and related fields. To see that this is the case one need only examine the various handbooks and encyclopaedic references that have been published in the last ten years to see the wide range of topics that have been covered. As with many…

Taming the Political: The Struggle over Recognition in the Politics of Applied Theatre

ERIC Educational Resources Information Center

Neelands, Jonothan

2007-01-01

The emerging sub-field of applied theater encompasses a wide range of pro-social 'alternative' theater practices, but it also refers to a discursive practice that seeks to reconcile the apparently contradictory claims of the politics of egalitarian redistribution and the politics of difference. The argument in this paper is that this emerging…

Clinical relevance of quantified fundus autofluorescence in diabetic macular oedema.

PubMed

Yoshitake, S; Murakami, T; Uji, A; Unoki, N; Dodo, Y; Horii, T; Yoshimura, N

2015-05-01

To quantify the signal intensity of fundus autofluorescence (FAF) and evaluate its association with visual function and optical coherence tomography (OCT) findings in diabetic macular oedema (DMO). We reviewed 103 eyes of 78 patients with DMO and 30 eyes of 22 patients without DMO. FAF images were acquired using Heidelberg Retina Angiograph 2, and the signal levels of FAF in the individual subfields of the Early Treatment Diabetic Retinopathy Study grid were measured. We evaluated the association between quantified FAF and the logMAR VA and OCT findings. One hundred and three eyes with DMO had lower FAF signal intensity levels in the parafoveal subfields compared with 30 eyes without DMO. The autofluorescence intensity in the parafoveal subfields was associated negatively with logMAR VA and the retinal thickness in the corresponding subfields. The autofluorescence levels in the parafoveal subfield, except the nasal subfield, were lower in eyes with autofluorescent cystoid spaces in the corresponding subfield than in those without autofluorescent cystoid spaces. The autofluorescence level in the central subfield was related to foveal cystoid spaces but not logMAR VA or retinal thickness in the corresponding area. Quantified FAF in the parafovea has diagnostic significance and is clinically relevant in DMO.

The Profession of Public Administration: An Ethics Edge in Introductory Textbooks?

ERIC Educational Resources Information Center

Bowman, James S.; Berman, Evan M.; West, Jonathan P.

2001-01-01

Examination of the foundations of public service ethics as reflected in 12 textbooks revealed that ethics coverage is modest and is seldom covered in areas in which ethical behavior is crucial. (Contains 57 references.) (JOW)

Frequency and Content Analysis of CFS in Medical Text Books

PubMed Central

Jason, Leonard A.; Paavola, Erin; Porter, Nicole; Morello, Morgan L.

2013-01-01

Textbooks are a cornerstone in the training of medical staff and students, and they are an important source of references and reviews for these professionals. The objective of this study was to determine both the quantity and quality of chronic fatigue syndrome (CFS) information included in medical texts. After reviewing 119 medical textbooks from various medical specialties, we found that 48 (40.3%) of the medical textbooks included information on CFS. However, among the 129,527 total pages within these medical textbooks, the CFS content was presented on only 116.3 (.090%) pages. Other illnesses that are less prevalent, such as Multiple Sclerosis and Lyme disease, were more frequently represented in medical textbooks. These findings suggest that the topic of CFS is under-reported in published medical textbooks. PMID:21128580

Volume of hippocampal subfields and episodic memory in childhood and adolescence.

PubMed

Lee, Joshua K; Ekstrom, Arne D; Ghetti, Simona

2014-07-01

Episodic memory critically depends on the hippocampus to bind the features of an experience into memory. Episodic memory develops in childhood and adolescence, and hippocampal changes during this period may contribute to this development. Little is known, however, about how the hippocampus contributes to episodic memory development. The hippocampus is comprised of several cytoarchitectural subfields with functional significance for episodic memory. However, hippocampal subfields have not been assessed in vivo during child development, nor has their relation with episodic memory been assessed during this period. In the present study, high-resolution T2-weighted images of the hippocampus were acquired in 39 children and adolescents aged 8 to 14 years (M=11.30, SD=2.38), and hippocampal subfields were segmented using a protocol previously validated in adult populations. We first validated the method in children and adolescents and examined age-related differences in hippocampal subfields and correlations between subfield volumes and episodic memory. Significant age-related increases in the subfield volume were observed into early adolescence in the right CA3/DG and CA1. The right CA3/DG subfield volumes were positively correlated with accurate episodic memory for item-color relations, and the right CA3/DG and subiculum were negatively correlated with item false alarm rates. Subfield development appears to follow a protracted developmental trajectory, and likely plays a pivotal role in episodic memory development. Copyright © 2014 Elsevier Inc. All rights reserved.

Clinical relevance of quantified fundus autofluorescence in diabetic macular oedema

PubMed Central

Yoshitake, S; Murakami, T; Uji, A; Unoki, N; Dodo, Y; Horii, T; Yoshimura, N

2015-01-01

Purpose To quantify the signal intensity of fundus autofluorescence (FAF) and evaluate its association with visual function and optical coherence tomography (OCT) findings in diabetic macular oedema (DMO). Methods We reviewed 103 eyes of 78 patients with DMO and 30 eyes of 22 patients without DMO. FAF images were acquired using Heidelberg Retina Angiograph 2, and the signal levels of FAF in the individual subfields of the Early Treatment Diabetic Retinopathy Study grid were measured. We evaluated the association between quantified FAF and the logMAR VA and OCT findings. Results One hundred and three eyes with DMO had lower FAF signal intensity levels in the parafoveal subfields compared with 30 eyes without DMO. The autofluorescence intensity in the parafoveal subfields was associated negatively with logMAR VA and the retinal thickness in the corresponding subfields. The autofluorescence levels in the parafoveal subfield, except the nasal subfield, were lower in eyes with autofluorescent cystoid spaces in the corresponding subfield than in those without autofluorescent cystoid spaces. The autofluorescence level in the central subfield was related to foveal cystoid spaces but not logMAR VA or retinal thickness in the corresponding area. Conclusions Quantified FAF in the parafovea has diagnostic significance and is clinically relevant in DMO. PMID:25771817

Macro- and Microthesauri: Changes Occurring in MeSH-Derived Thesauri and a Solution to Some Related Search Handicaps.

ERIC Educational Resources Information Center

Kirtland, Monika

1981-01-01

Outlines a methodology for standardizing word lists of subject- related fields using a macrothesaurus which provides basic classification structure and terminology for the subject at large and which adapts to the specific needs of its subfields. The example of the Cancer Information Thesaurus (CIT) is detailed. Six references are listed. (FM)

Didactic Transposition in Mathematics Textbooks.

ERIC Educational Resources Information Center

Kang, Wan; Kilpatrick, Jeremy

1992-01-01

Didactic transposition theory asserts that bodies of knowledge are designed not to be taught but to be used. Discusses didactic transposition, the transposition of knowledge regarded as a tool to be used to knowledge as something to be learned in mathematics textbooks. (14 references) (MDH)

Hippocampal subfield segmentation in temporal lobe epilepsy: Relation to outcomes.

PubMed

Kreilkamp, B A K; Weber, B; Elkommos, S B; Richardson, M P; Keller, S S

2018-06-01

To investigate the clinical and surgical outcome correlates of preoperative hippocampal subfield volumes in patients with refractory temporal lobe epilepsy (TLE) using a new magnetic resonance imaging (MRI) multisequence segmentation technique. We recruited 106 patients with TLE and hippocampal sclerosis (HS) who underwent conventional T1-weighted and T2 short TI inversion recovery MRI. An automated hippocampal segmentation algorithm was used to identify twelve subfields in each hippocampus. A total of 76 patients underwent amygdalohippocampectomy and postoperative seizure outcome assessment using the standardized ILAE classification. Semiquantitative hippocampal internal architecture (HIA) ratings were correlated with hippocampal subfield volumes. Patients with left TLE had smaller volumes of the contralateral presubiculum and hippocampus-amygdala transition area compared to those with right TLE. Patients with right TLE had reduced contralateral hippocampal tail volumes and improved outcomes. In all patients, there were no significant relationships between hippocampal subfield volumes and clinical variables such as duration and age at onset of epilepsy. There were no significant differences in any hippocampal subfield volumes between patients who were rendered seizure free and those with persistent postoperative seizure symptoms. Ipsilateral but not contralateral HIA ratings were significantly correlated with gross hippocampal and subfield volumes. Our results suggest that ipsilateral hippocampal subfield volumes are not related to the chronicity/severity of TLE. We did not find any hippocampal subfield volume or HIA rating differences in patients with optimal and unfavorable outcomes. In patients with TLE and HS, sophisticated analysis of hippocampal architecture on MRI may have limited value for prediction of postoperative outcome. © 2018 The Authors. Acta Neurologica Scandinavica Published by John Wiley & Sons Ltd.

Representations of rituals and care in perinatal death in British midwifery textbooks 1937-2004.

PubMed

Cameron, Joan; Taylor, Julie; Greene, Alexandra

2008-09-01

to assess the evolution of attitudes and practices relating to perinatal loss through an analysis of British midwifery textbooks. a literature review of midwifery textbooks, written or edited by midwives, published in the UK after 1902, and a critical analysis of textbooks to determine the ideological and professional standpoints presented to readers. the rhetoric and ritual relating to perinatal loss as portrayed in British midwifery textbooks has changed, with the most dramatic changes taking place in the past 30 years. Evidence to support the changes is largely anecdotal, and little reference is made to research relating to perinatal death. The 'dirty' elements of perinatal death relating to the decay that takes place in the baby's body after death are not addressed. The critique of psychological theory relating to loss is absent, as are alternatives to the model proposed by Kübler Ross. Cultural aspects of loss and bereavement are rarely addressed. the review of midwifery textbooks suggests that an ideological shift has taken place in relation to perinatal loss. The changing demographic trends, and the shift of birth and death from home to hospital, have altered the expectations and experiences of parents and professionals. Midwifery textbooks provide readers with a prescribed and formulaic approach to perinatal loss. the absence of information relating to the appearance of the dead baby, together with the lack of clinical exposure, may mean that midwives are unable to provide parents with appropriate information. The lack of reference to an evidence base that may conflict with the ideology presented in the midwifery textbooks leaves readers with an incomplete understanding of the professional issues relating to perinatal loss.

Radiological Defense. Textbook.

ERIC Educational Resources Information Center

Defense Civil Preparedness Agency (DOD), Washington, DC.

This textbook has been prepared under the direction of the Defense Civil Preparedness Agency (DCPA) Staff College for use as a student reference manual in radiological defense (RADEF) courses. It provides much of the basic technical information necessary for a proper understanding of radiological defense and summarizes RADEF planning and expected…

Textbook Errors and Misconceptions in Biology: Cell Physiology.

ERIC Educational Resources Information Center

Storey, Richard D.

1992-01-01

Considers topics about cell function often misunderstood, misrepresented, or omitted from biology textbooks: enzyme catalyzed reactions; RNA as a catalyst; protein levels in cells; amino acids; organic acids; glucose and fructose; gluconeogenesis; fatty acids and ketone bodies; diffusion; and transport across membranes. (Contains 25 references.)…

History of science content analysis of Chinese science textbooks from the perspective of acculturation

NASA Astrophysics Data System (ADS)

Ma, Yongjun; Wan, Yanlan

2017-08-01

Based on previous international studies, a content analysis scheme has been designed and used from the perspective of culture to study the history of science (HOS) in science textbooks. Nineteen sets of Chinese science textbooks have been analyzed. It has been found that there are noticeable changes in the quantity, content, layout, presentation, and writing intention of the HOS sections in textbooks from different time periods. What's more, the textbooks aim at presenting the scientific culture and aim to help students understand it better. However, the cultural associations of the HOS in textbooks is insufficient and significant differences exist among textbooks of different subjects. In order to explore the reasons why the presentation of HOS in various subjects is different, we made a specific comparison of curriculum standards of two subjects with great differences and interviewed the editors-in-chief of two textbooks. Results show that one of the most important reasons for the different writings of the HOS in textbooks is that different subject curriculum standards attach greater importance to the HOS. In addition, the attention to the HOS by editors-in-chief, the tradition of studying the HOS within the history of the discipline, and the reference textbooks in compiling textbooks are all important influence factors. Some suggestions for future textbooks compilation are given at the end.

Regional hippocampal volumes and development predict learning and memory.

PubMed

Tamnes, Christian K; Walhovd, Kristine B; Engvig, Andreas; Grydeland, Håkon; Krogsrud, Stine K; Østby, Ylva; Holland, Dominic; Dale, Anders M; Fjell, Anders M

2014-01-01

The hippocampus is an anatomically and functionally heterogeneous structure, but longitudinal studies of its regional development are scarce and it is not known whether protracted maturation of the hippocampus in adolescence is related to memory development. First, we investigated hippocampal subfield development using 170 longitudinally acquired brain magnetic resonance imaging scans from 85 participants aged 8-21 years. Hippocampal subfield volumes were estimated by the use of automated segmentation of 7 subfields, including the cornu ammonis (CA) sectors and the dentate gyrus (DG), while longitudinal subfield volumetric change was quantified using a nonlinear registration procedure. Second, associations between subfield volumes and change and verbal learning/memory across multiple retention intervals (5 min, 30 min and 1 week) were tested. It was hypothesized that short and intermediate memory would be more closely related to CA2-3/CA4-DG and extended, remote memory to CA1. Change rates were significantly different across hippocampal subfields, but nearly all subfields showed significant volume decreases over time throughout adolescence. Several subfield volumes were larger in the right hemisphere and in males, while for change rates there were no hemisphere or sex differences. Partly in support of the hypotheses, greater volume of CA1 and CA2-3 was related to recall and retention after an extended delay, while longitudinal reduction of CA2-3 and CA4-DG was related to learning. This suggests continued regional development of the hippocampus across adolescence and that volume and volume change in specific subfields differentially predict verbal learning and memory over different retention intervals, but future high-resolution studies are called for. © 2014 S. Karger AG, Basel.

Automated Volumetry and Regional Thickness Analysis of Hippocampal Subfields and Medial Temporal Cortical Structures in Mild Cognitive Impairment

PubMed Central

Yushkevich, Paul A.; Pluta, John B.; Wang, Hongzhi; Xie, Long; Ding, Song-Lin; Gertje, E. C.; Mancuso, Lauren; Kliot, Daria; Das, Sandhitsu R.; Wolk, David A.

2014-01-01

We evaluate a fully automatic technique for labeling hippocampal subfields and cortical subregions in the medial temporal lobe (MTL) in in vivo 3 Tesla MRI. The method performs segmentation on a T2-weighted MRI scan with 0.4 × 0.4 × 2.0 mm3 resolution, partial brain coverage, and oblique orientation. Hippocampal subfields, entorhinal cortex, and perirhinal cortex are labeled using a pipeline that combines multi-atlas label fusion and learning-based error correction. In contrast to earlier work on automatic subfield segmentation in T2-weighted MRI (Yushkevich et al., 2010), our approach requires no manual initialization, labels hippocampal subfields over a greater anterior-posterior extent, and labels the perirhinal cortex, which is further subdivided into Brodmann areas 35 and 36. The accuracy of the automatic segmentation relative to manual segmentation is measured using cross-validation in 29 subjects from a study of amnestic Mild Cognitive Impairment (aMCI), and is highest for the dentate gyrus (Dice coefficient is 0.823), CA1 (0.803), perirhinal cortex (0.797) and entorhinal cortex (0.786) labels. A larger cohort of 83 subjects is used to examine the effects of aMCI in the hippocampal region using both subfield volume and regional subfield thickness maps. Most significant differences between aMCI and healthy aging are observed bilaterally in the CA1 subfield and in the left Brodmann area 35. Thickness analysis results are consistent with volumetry, but provide additional regional specificity and suggest non-uniformity in the effects of aMCI on hippocampal subfields and MTL cortical subregions. PMID:25181316

Differential effect of age on hippocampal subfields assessed using a new high-resolution 3T MR sequence.

PubMed

La Joie, Renaud; Fouquet, Marine; Mézenge, Florence; Landeau, Brigitte; Villain, Nicolas; Mevel, Katell; Pélerin, Alice; Eustache, Francis; Desgranges, Béatrice; Chételat, Gaël

2010-11-01

Recent advances in neuroimaging have highlighted the interest to differentiate hippocampal subfields for cognitive neurosciences and more notably in assessing the effects of normal and pathological aging. The main goal of the present study is to investigate the effects of normal aging onto the volume of the different hippocampal subfields. For this purpose, we developed a new magnetic resonance sequence together with reliable tracing guidelines to assess the volume of different subfields of the hippocampus using a 3 Tesla scanner, and estimated the validity of a simpler and less time-consuming method based on the widely-used automatic Voxel-Based Morphometry (VBM) technique. Three hippocampal regions of interest were delineated on the right and left hippocampi of 50 healthy subjects between 18 and 68 years old corresponding to the CA1, subiculum and other (including CA2-3-4 and Dentate Gyrus) subfields. A strong effect of age was found on the volume of the subiculum only, with a decrease paralleling that of the global gray matter volume, while CA1 and other subfields seemed relatively spared. Although less precise than the ROI-tracing technique, the VBM-based method appeared as a reliable alternative especially to distinguish CA1 and subiculum subfields. Our findings of a specific effect of age on the subiculum are consistent with the developmental hypothesis ("last-in first-out" theory). This contrasts with the predominant vulnerability of the CA1 subfield to Alzheimer's disease reported in several previous studies, suggesting that the assessment of hippocampal subfields may improve the discrimination between normal and pathological aging. Copyright 2010 Elsevier Inc. All rights reserved.

Smaller stress-sensitive hippocampal subfields in women with borderline personality disorder without posttraumatic stress disorder.

PubMed

Bøen, Erlend; Westlye, Lars T; Elvsåshagen, Torbjørn; Hummelen, Benjamin; Hol, Per K; Boye, Birgitte; Andersson, Stein; Karterud, Sigmund; Malt, Ulrik F

2014-03-01

Animal and human studies have suggested that hippocampal subfields are differentially vulnerable to stress, but subfield volume has not been investigated in patients with borderline personality disorder (BPD). Based on the putative role of stressful life events as vulnerability factors for BPD, we hypothesized that patients with BPD would exhibit reduced volumes for the stress-sensitive dentate gyrus (DG) and the cornu ammonis (CA) 3 subfields volumes, and that these volumes would be associated with traumatic childhood experiences. All participants underwent 3 T magnetic resonance imaging. Hippocampal subfield volumes were estimated using an automated and validated segmentation algorithm implemented in FreeSurfer. Age and total subcortical grey matter volume were covariates. We assessed traumatic childhood experiences using the Childhood Trauma Questionnaire (CTQ). A total of 18 women with BPD and 21 healthy control women were included in the study. Only 1 patient had comorbid posttraumatic stress disorder (PTSD). The volumes of the left (p = 0.005) and right (p = 0.011) DG-CA4 and left (p = 0.007) and right (p = 0.005) CA2-3 subfields were significantly reduced in patients compared with controls. We also found significant group differences for the left (p = 0.032) and right (p = 0.028) CA1, but not for other hippocampal subfields. No associations were found between CTQ scores and subfield volumes. The self-reported CTQ might be inferior to more comprehensive assessments of traumatic experiences. The sample size was moderate. The volumes of stress-sensitive hippocampal subfields are reduced in women with BPD without PTSD. However, the degree to which childhood trauma is responsible for these changes is unclear.

Smaller stress-sensitive hippocampal subfields in women with borderline personality disorder without posttraumatic stress disorder

PubMed Central

Bøen, Erlend; Westlye, Lars T.; Elvsåshagen, Torbjørn; Hummelen, Benjamin; Hol, Per K.; Boye, Birgitte; Andersson, Stein; Karterud, Sigmund; Malt, Ulrik F.

2014-01-01

Background Animal and human studies have suggested that hippocampal subfields are differentially vulnerable to stress, but subfield volume has not been investigated in patients with borderline personality disorder (BPD). Based on the putative role of stressful life events as vulnerability factors for BPD, we hypothesized that patients with BPD would exhibit reduced volumes for the stress-sensitive dentate gyrus (DG) and the cornu ammonis (CA) 3 subfields volumes, and that these volumes would be associated with traumatic childhood experiences. Methods All participants underwent 3 T magnetic resonance imaging. Hippocampal subfield volumes were estimated using an automated and validated segmentation algorithm implemented in FreeSurfer. Age and total subcortical grey matter volume were covariates. We assessed traumatic childhood experiences using the Childhood Trauma Questionnaire (CTQ). Results A total of 18 women with BPD and 21 healthy control women were included in the study. Only 1 patient had comorbid posttraumatic stress disorder (PTSD). The volumes of the left (p = 0.005) and right (p = 0.011) DG-CA4 and left (p = 0.007) and right (p = 0.005) CA2–3 subfields were significantly reduced in patients compared with controls. We also found significant group differences for the left (p = 0.032) and right (p = 0.028) CA1, but not for other hippocampal subfields. No associations were found between CTQ scores and subfield volumes. Limitations The self-reported CTQ might be inferior to more comprehensive assessments of traumatic experiences. The sample size was moderate. Conclusion The volumes of stress-sensitive hippocampal subfields are reduced in women with BPD without PTSD. However, the degree to which childhood trauma is responsible for these changes is unclear. PMID:24309162

Similarity of Introductory Psychology Textbooks: Reality or Illusion?

ERIC Educational Resources Information Center

Griggs, Richard A.; Marek, Pam

2001-01-01

Presents a study that reviewed introductory psychology textbooks to examine the perception of extensive similarity. Focuses on six dimensions: (1) chapter topics, organization, and extent of topic coverage; (2) core concepts and key terms; (3) pedagogical aids and data graphs; (4) critical-thinking programs; (5) reference citations; and (6) level…

Mystery in Milwaukee: Early Intervention, IQ, and Psychology Textbooks.

ERIC Educational Resources Information Center

Sommer, Robert; Sommer, Barbara A.

1983-01-01

Textbooks in developmental and abnormal psychology were examined for references to the Milwaukee study of the effects of early intervention on intelligence. The absence of citations to articles in refereed journals shows how research data of questionable validity can seep into the research literature without going through the journal review…

Indexing of Iranian Publications in Well-known Endodontic Textbooks: A Scientometric Analysis.

PubMed

Kakooei, Sina; Mostafavi, Mahshid; Parirokh, Masoud; Asgary, Saeed

2016-01-01

Quoting an article in well-known textbooks is held as a credit for that paper. The numbers of Iranian publications mentioned in endodontic textbooks have increased during recent years. The aim of this investigation was to evaluate the number of Iranian articles quoted in eminent endodontic textbooks. Three known textbooks (Ingle's Endodontics, Seltzer and Bender's Dental Pulp and Cohen's Pathways of the Pulp) were chosen and all the editions of the textbooks since 2000 were investigated for quoted Iranian publications. Only Iranian authors with affiliations from a domestic university were chosen. All references at the end of each chapter were read by hand searching, and results were noted. The trend and percentage of Iranian publications in different editions of the textbooks were also calculated. The number of citations of these publications in Google Scholar and Scopus databases were also obtained. The number of Iranian publications in all well-known textbooks have notably increased since 2000. The number and percentage of Iranian publications in the latest edition of Cohen's Pathways of the Pulp was higher compared to other textbooks as well as the previous edition of the same text. Number and percentage of Iranian publications in the field of endodontics in all three textbooks have remarkably increased since 2000.

How to Build Bridges between Intelligent Tutoring System Subfields of Research

ERIC Educational Resources Information Center

Pavlik, Philip, Jr.; Toth, Joe

2010-01-01

The plethora of different subfields in intelligent tutoring systems (ITS) are often difficult to integrate theoretically when analyzing how to design an intelligent tutor. Important principles of design are claimed by many subfields, including but not limited to: design, human-computer interaction, perceptual psychology, cognitive psychology,…

Altered Whole-Brain Structural Covariance of the Hippocampal Subfields in Subcortical Vascular Mild Cognitive Impairment and Amnestic Mild Cognitive Impairment Patients.

PubMed

Wang, Xuetong; Yu, Yang; Zhao, Weina; Li, Qiongling; Li, Xinwei; Li, Shuyu; Yin, Changhao; Han, Ying

2018-01-01

The hippocampus plays important roles in memory processing. However, the hippocampus is not a homogeneous structure, which consists of several subfields. The hippocampal subfields are differently affected by many neurodegenerative diseases, especially mild cognitive impairment (MCI). Amnestic mild cognitive impairment (aMCI) and subcortical vascular mild cognitive impairment (svMCI) are the two subtypes of MCI. aMCI is characterized by episodic memory loss, and svMCI is characterized by extensive white matter hyperintensities and multiple lacunar infarctions on magnetic resonance imaging. The primary cognitive impairment in svMCI is executive function, attention, and semantic memory. Some variations or disconnections within specific large-scale brain networks have been observed in aMCI and svMCI patients. The aim of this study was to investigate abnormalities in structural covariance networks (SCNs) between hippocampal subfields and the whole cerebral cortex in aMCI and svMCI patients, and whether these abnormalities are different between the two groups. Automated segmentation of hippocampal subfields was performed with FreeSurfer 5.3, and we selected five hippocampal subfields as the seeds of SCN analysis: CA1, CA2/3, CA4/dentate gyrus (DG), subiculum, and presubiculum. SCNs were constructed based on these hippocampal subfield seeds for each group. Significant correlations between hippocampal subfields, fusiform gyrus (FFG), and entorhinal cortex (ERC) in gray matter volume were found in each group. We also compared the differences in the strength of structural covariance between any two groups. In the aMCI group, compared to the normal controls (NC) group, we observed an increased association between the left CA1/CA4/DG/subiculum and the left temporal pole. Additionally, the hippocampal subfields (bilateral CA1, left CA2/3) significantly covaried with the orbitofrontal cortex in the svMCI group compared to the NC group. In the aMCI group compared to the svMCI group, we observed decreased association between hippocampal subfields and the right FFG, while we also observed an increased association between the bilateral subiculum/presubiculum and bilateral ERC. These findings provide new evidence that there is altered whole-brain structural covariance of the hippocampal subfields in svMCI and aMCI patients and provide insights to the pathological mechanisms of different MCI subtypes.

Presentation of Atomic Structure in Turkish General Chemistry Textbooks

ERIC Educational Resources Information Center

Niaz, Mansoor; Costu, Bayram

2009-01-01

Research in science education has recognized the importance of teaching atomic structure within a history and philosophy of science perspective. The objective of this study is to evaluate general chemistry textbooks published in Turkey based on the eight criteria developed in previous research. Criteria used referred to the atomic models of…

What Really Happens to Complimentary Textbook Software? A Case Study in Software Utilization.

ERIC Educational Resources Information Center

Vernon, Robert F.

1993-01-01

Discussion of complimentary computer software for college-level textbooks focuses on a study that investigated how a complimentary program was used and identified factors that influenced its use or nonuse. Barriers to use are described, including personal, technical, process, political, and economic factors. (Contains four references.) (LRW)

Challenging Substantive Knowledge in Educational Media: A Case Study of German History Textbooks

ERIC Educational Resources Information Center

Garske, Lucas Frederik

2017-01-01

Many scholars working on history education have stressed that, in order to "do history," a congruent relation between substantive and procedural knowledge is required. In response to this argument, this article emphasizes the need to consider pupils' relations to substantive knowledge. With reference to history textbooks currently used…

The Oil Drop Experiment: Do Physical Chemistry Textbooks Refer to Its Controversial Nature?

ERIC Educational Resources Information Center

Niaz, Mansoor; Rodriguez, Maria A.

2005-01-01

Most general chemistry textbooks consider the oil drop experiment as a classic experiment, characterized by its simplicity and precise results. A review of the history and philosophy of science literature shows that the experiment is difficult to perform (even today!) and generated a considerable amount of controversy. Acceptance of the…

Genetic Determinism in School Textbooks: A Comparative Study Conducted among Sixteen Countries

ERIC Educational Resources Information Center

Castera, Jeremy; Clement, Pierre; Abrougui, Mondher; Nisiforou, Olympia; Valanides, Nicos; Turcinaviciene, Jurga; Sarapuu, Tago; Agorram, Boujemaa; Calado, Florbela; Bogner, Franz; Carvalho, Graca

2008-01-01

Genetic concepts have significantly evolved over the last ten years, and are now less connected to innate ideas and reductionism. Unique reference to genetic determinism has been replaced by the interaction between the genes and their environment (epigenetics). Our analyses relate to how current school biology textbooks present this new paradigm…

Genetic Diseases and Genetic Determinism Models in French Secondary School Biology Textbooks

ERIC Educational Resources Information Center

Castera, Jeremy; Bruguiere, Catherine; Clement, Pierre

2008-01-01

The presentation of genetic diseases in French secondary school biology textbooks is analysed to determine the major conceptions taught in the field of human genetics. References to genetic diseases, and the processes by which they are explained (monogeny, polygeny, chromosomal anomaly and environmental influence) are studied in recent French…

Resources and References for Earth Science Teachers

ERIC Educational Resources Information Center

Wall, Charles A.; Wall, Janet E.

1976-01-01

Listed are resources and references for earth science teachers including doctoral research, new textbooks, and professional literature in astronomy, space science, earth science, geology, meteorology, and oceanography. (SL)

Resource Letter L-1: Lasers.

ERIC Educational Resources Information Center

O'Shea, Donald C.; Peckham, Donald C.

1981-01-01

Following a brief introduction, an annotated listing of literature and teaching aids on lasers is presented. Categories include: Background Materials; Historical References; General References and Textbooks; Specialized References; Reviews; Articles; Films; Laser Courses; Equipment, Demonstrations, and Experiments; Laser Safety; and Lasers and…

Physics in perspective. Volume 2, part A: The core subfields of physics

NASA Technical Reports Server (NTRS)

1972-01-01

Panel reports to the Survey Committee are presented to provide detailed technical background and documentation for committee findings, and to indicate the vitality and strength of the subfields of physics. Included are the core subfields of acoustics, optics, condensed matter, plasmas and fluids, atomic molecular and electron physics, nuclear physics, and elementary particle physics.

Critical Analysis of Textbooks: Knowledge-Generating Logics and the Emerging Image of "Global Economic Contexts"

ERIC Educational Resources Information Center

Thoma, Michael

2017-01-01

This paper presents an approach to the critical analysis of textbook knowledge, which, working from a discourse theory perspective (based on the work of Foucault), refers to the performative nature of language. The critical potential of the approach derives from an analysis of knowledge-generating logics, which produce particular images of reality…

Pre-Calculus Instructional Guide for Elementary Functions, Analytic Geometry.

ERIC Educational Resources Information Center

Montgomery County Public Schools, Rockville, MD.

This is a guide for use in semester-long courses in Elementary Functions and Analytic Geometry. A list of entry-level skills and a list of approved textbooks is provided. Each of the 18 units consists of: (1) overview, suggestions for teachers, and suggested time; (2) list of objectives; (3) cross-references guide to approved textbooks; (4) sample…

Bringing Women in: Gender and American Government and Politics Textbooks

ERIC Educational Resources Information Center

Olivo, Christiane

2012-01-01

This study of 12 introductory American government and politics textbooks shows that their main narratives still focus largely on men's experiences as political actors and pay little attention to women's experiences. While on average just 9% of pages included in-text references to women, 28% of images and 17% of sidebars, tables, figures, and…

Forensic psychology and correctional psychology: Distinct but related subfields of psychological science and practice.

PubMed

Neal, Tess M S

2018-02-12

This article delineates 2 separate but related subfields of psychological science and practice applicable across all major areas of the field (e.g., clinical, counseling, developmental, social, cognitive, community). Forensic and correctional psychology are related by their historical roots, involvement in the justice system, and the shared population of people they study and serve. The practical and ethical contexts of these subfields is distinct from other areas of psychology-and from one another-with important implications for ecologically valid research and ethically sound practice. Forensic psychology is a subfield of psychology in which basic and applied psychological science or scientifically oriented professional practice is applied to the law to help resolve legal, contractual, or administrative matters. Correctional psychology is a subfield of psychology in which basic and applied psychological science or scientifically oriented professional practice is applied to the justice system to inform the classification, treatment, and management of offenders to reduce risk and improve public safety. There has been and continues to be great interest in both subfields-especially the potential for forensic and correctional psychological science to help resolve practical issues and questions in legal and justice settings. This article traces the shared and separate developmental histories of these subfields, outlines their important distinctions and implications, and provides a common understanding and shared language for psychologists interested in applying their knowledge in forensic or correctional contexts. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

An Analytical Framework for Categorizing the Use of CAS Symbolic Manipulation in Textbooks

ERIC Educational Resources Information Center

Davis, Jon D.; Fonger, Nicole L.

2015-01-01

The symbolic manipulation capabilities of computer algebra systems, which we refer to as CAS-S, are now becoming instantiated within secondary mathematics textbooks in the United States for the first time. While a number of research studies have examined how teachers use this technology in their classrooms, one of the most important factors in how…

Special Women in My Life: Strategies for Writing Women into the Social Studies Curriculum

ERIC Educational Resources Information Center

Hickey, M. Gail; Kolterman, Don L.

2006-01-01

Women have always been a part of history, but society has not always recognized their contributions. History textbooks, for example, largely portray women as passive bystanders in the world's events, with fewer than 11 percent of textbook images and references devoted to specific women. A U.S. Congressional Resolution designated March as Women's…

Political Partisanship, Bureaucratic Pragmatism and Acadian Nationalism: New Brunswick, Canada's 1920 History Textbook Controversy

ERIC Educational Resources Information Center

Helyar, Frances

2014-01-01

During a time of post-war sensitivity to Canadian nationalism and patriotism, public feeling was aroused in 1920 New Brunswick regarding a world history textbook with a new chapter about the First World War. The American author made no reference to Canada's war efforts. The subsequent public discussion focused on issues of patriotism, citizenship,…

Recent Trends in Japanese Mathematics Textbooks for Elementary Grades: Supporting Teachers to Teach Mathematics through Problem Solving

ERIC Educational Resources Information Center

Takahashi, Akihiko

2016-01-01

Problem solving has been a major theme in Japanese mathematics curricula for nearly 50 years. Numerous teacher reference books and lesson plans using problem solving have been published since the 1960s. Government-authorized mathematics textbooks for elementary grades, published by six private companies, have had more and more problem solving over…

Upper Secondary Students' Understanding of the Use of Multiple Models in Biology Textbooks--The Importance of Conceptual Variation and Incommensurability

ERIC Educational Resources Information Center

Gericke, Niklas; Hagberg, Mariana; Jorde, Doris

2013-01-01

In this study we investigate students' ability to discern conceptual variation and the use of multiple models in genetics when reading content-specific excerpts from biology textbooks. Using the history and philosophy of science as our reference, we were able to develop a research instrument allowing students themselves to investigate the…

Education and Religion in Iran: The Inclusiveness of EFL (English as a Foreign Language) Textbooks

ERIC Educational Resources Information Center

Cheng, Karen Kow Yip; Beigi, Amir Biglar

2012-01-01

The focus of this paper is religion and education with particular reference to EFL (English as a Foreign Language) textbooks. The writers of this paper aim to raise the awareness of research community, educators, and teachers regarding the interconnectedness of religion and education. In the first phase of the study, the researchers scanned a…

[Investigation of the publishing and using status of college genetics textbooks in China].

PubMed

Chen, Xiwen; Chen, Defu

2014-04-01

Using Wenjin Search of the National Library of China, it was found that 895 genetics textbooks for Chinese colleges, including 588 (67.5%) theoretical books, 122 (13.6%) experimental books and 185 (20.7%) teaching reference books, have been published since College Entrance Examination resumed. Most of these books belong to medical genetics, followed by general genetics, while the books on plant genetics, animal genetics or microbial genetics are relatively few. In these search results, 91 had the same name of Medical Genetics, professor Ji Zuo is the most productive author, who edited 9 genetics textbooks, and Science Press Ltd. is the most productive press, which published 179 (20%) genetics textbooks. The questionnaire survey showed that "Genetics" (Second Edition) edited by Zhuohua Dai is the most widely used textbooks in the Chinese colleges, while the mainly used experimental books are the handouts or self-edited textbooks. Finally, we analyzed the problems currently existed in the textbooks, such as slowly updating cycle, less supports, lots of books with the same name, lack of scientific stories, very rare and unique illustrations, too full printed pages, and also provided the proposed solution.

CA1 and CA3 differentially support spontaneous retrieval of episodic contexts within human hippocampal subfields.

PubMed

Dimsdale-Zucker, Halle R; Ritchey, Maureen; Ekstrom, Arne D; Yonelinas, Andrew P; Ranganath, Charan

2018-01-18

The hippocampus plays a critical role in spatial and episodic memory. Mechanistic models predict that hippocampal subfields have computational specializations that differentially support memory. However, there is little empirical evidence suggesting differences between the subfields, particularly in humans. To clarify how hippocampal subfields support human spatial and episodic memory, we developed a virtual reality paradigm where participants passively navigated through houses (spatial contexts) across a series of videos (episodic contexts). We then used multivariate analyses of high-resolution fMRI data to identify neural representations of contextual information during recollection. Multi-voxel pattern similarity analyses revealed that CA1 represented objects that shared an episodic context as more similar than those from different episodic contexts. CA23DG showed the opposite pattern, differentiating between objects encountered in the same episodic context. The complementary characteristics of these subfields explain how we can parse our experiences into cohesive episodes while retaining the specific details that support vivid recollection.

Differential impact of science policy on subfields of human embryonic stem cell research.

PubMed

Moon, Seongwuk; Cho, Seong Beom

2014-01-01

In this research, we examine how restrictive policy influenced performance in human embryonic stem cell research (hESC) between 1998 and 2008. In previous research, researchers argued whether restrictive policy decreased the performance of stem cell research in some nations, especially in the US. Here, we hypothesize that this policy influenced specific subfields of the hESC research. To investigate the selective policy effects, we categorize hESC research publications into three subfields-derivation, differentiation, and medical application research. Our analysis shows that restrictive policy had different effects on different subfields. In general, the US outperformed in overall hESC research throughout these periods. In the derivation of hESC, however, the US almost lost its competence under restrictive policy. Interestingly, the US scientific community showed prominent resilience in hESC research through international collaboration. We concluded that the US resilience and performance stemmed from the wide breadth of research portfolio of US scientists across the hESC subfields, combined with their strategic efforts to collaborate internationally on derivation research.

Towards an Intelligent Textbook of Neurology

PubMed Central

Reggia, James A.; Pula, Thaddeus P.; Price, Thomas R.; Perricone, Barry T.

1980-01-01

We define an intelligent textbook of medicine to be a computer system that: (1) provides for storage and selective retrieval of synthesized clinical knowledge for reference purposes; and (2) supports the application by computer of its knowledge to patient information to assist physicians with decision making. This paper describes an experimental system called KMS (a Knowledge Management System) for creating and using intelligent medical textbooks. KMS is domain-independent, supports multiple inference methods and representation languages, and is designed for direct use by physicians during the knowledge acquisition process. It is presented here in the context of the development of an Intelligent Textbook of Neurology. We suggest that KMS has the potential to overcome some of the problems that have inhibited the use of knowledge-based systems by physicians in the past.

Effects of low-level sarin and cyclosarin exposure on hippocampal subfields in Gulf War Veterans.

PubMed

Chao, Linda L; Kriger, Stephen; Buckley, Shannon; Ng, Peter; Mueller, Susanne G

2014-09-01

More than 100,000 US troops were potentially exposed to chemical warfare agents sarin (GB) and cyclosarin (GF) when an ammunition dump at Khamisiyah, Iraq was destroyed during the 1991 Gulf War (GW). We previously reported reduced hippocampal volume in GW veterans with suspected GB/GF exposure relative to matched, unexposed GW veterans estimated from 1.5T magnetic resonance images (MRI). Here we investigate, in a different cohort of GW veterans, whether low-level GB/GF exposure is associated with structural alterations in specific hippocampal subfields, estimated from 4T MRI. The Automatic Segmentation of Hippocampal Subfields (ASHS) technique was used to quantify CA1, CA2, CA3 and dentate gyrus (DG), and subiculum (SUB) subfields volumes from high-resolution T2-weighted images acquired on a 4T MR scanner in 56 GW veterans with suspected GB/GF exposure and 56 "matched" unexposed GW veterans (mean age 49±7 years). GB/GF exposed veterans had smaller CA2 (p=0.003) and CA3/DG (p=0.01) subfield volumes compared to matched, unexposed GW veterans. There were no group difference in total hippocampal volume, quantified with FreeSurfer, and no dose-response relationship between estimated levels of GB/GF exposure and total hippocampal or subfield volume. These findings extend our previous report of structural alterations in the hippocampi of GW veterans with suspected GB/GF exposure to volume changes in the CA2, CA3, and DG hippocampal subfields in a different cohort of GW veterans with suspected GB/GF exposure. Published by Elsevier B.V.

Differential Atrophy of Hippocampal Subfields: A Comparative Study of Dementia with Lewy Bodies and Alzheimer Disease.

PubMed

Mak, Elijah; Su, Li; Williams, Guy B; Watson, Rosie; Firbank, Michael; Blamire, Andrew; O'Brien, John

2016-02-01

Dementia with Lewy bodies (DLB) is characterized by relative preservation of the medial temporal lobe compared with Alzheimer disease (AD). The differential involvement of the hippocampal subfields in both diseases has not been clearly established, however. We aim to investigate hippocampal subfield differences in vivo in a clinical cohort of DLB and AD subjects. 104 participants (35 DLBs, 36 ADs, and 35 healthy comparison [HC] subjects) underwent clinical assessment and 3T T1-weighted imaging. A Bayesian model implemented in Freesurfer was used to automatically segment the hippocampus and its subfields. We also examined associations between hippocampal subfields and tests of memory function. Both the AD and DLB groups demonstrated significant atrophy of the total hippocampus relative to HC but the DLB group was characterized by preservation of the cornu ammonis 1 (CA1), fimbria, and fissure. In contrast, all the hippocampal subfields except the fissure were significantly atrophied in AD compared with both DLB and HC groups. Among DLB subjects, CA1 was correlated with the Recent Memory score of the CAMCOG and Delayed Recall subscores of the HVLT. DLB is characterized by milder hippocampal atrophy that was accompanied by preservation of the CA1. The CA1 was also associated with memory function in DLB. Our findings highlight the promising role of hippocampal subfield volumetry, particularly that of the CA1, as a biomarker for the distinction between AD and DLB. Copyright © 2016 American Association for Geriatric Psychiatry. Published by Elsevier Inc. All rights reserved.

Development of hippocampal subfield volumes from 4 to 22 years.

PubMed

Krogsrud, Stine K; Tamnes, Christian K; Fjell, Anders M; Amlien, Inge; Grydeland, Håkon; Sulutvedt, Unni; Due-Tønnessen, Paulina; Bjørnerud, Atle; Sølsnes, Anne E; Håberg, Asta K; Skrane, Jon; Walhovd, Kristine B

2014-11-01

The hippocampus supports several important cognitive functions known to undergo substantial development during childhood and adolescence, for example, encoding and consolidation of vivid personal memories. However, diverging developmental effects on hippocampal volume have been observed across studies. It is possible that the inconsistent findings may attribute to varying developmental processes and functions related to different hippocampal subregions. Most studies to date have measured global hippocampal volume. We aimed to explore early hippocampal development both globally and regionally within subfields. Using cross-sectional 1.5 T magnetic resonance imaging data from 244 healthy participants aged 4-22 years, we performed automated hippocampal segmentation of seven subfield volumes; cornu ammonis (CA) 1, CA2/3, CA4/dentate gyrus (DG), presubiculum, subiculum, fimbria, and hippocampal fissure. For validation purposes, seven subjects were scanned at both 1.5 and 3 T, and all subfields except fimbria showed strong correlations across field strengths. Effects of age, left and right hemisphere, sex and their interactions were explored. Nonparametric local smoothing models (smoothing spline) were used to depict age-trajectories. Results suggested nonlinear age functions for most subfields where volume increases until 13-15 years, followed by little age-related changes during adolescence. Further, the results showed greater right than left hippocampal volumes that seemed to be augmenting in older age. Sex differences were also found for subfields; CA2/3, CA4/DG, presubiculum, subiculum, and CA1, mainly driven by participants under 13 years. These results provide a detailed characterization of hippocampal subfield development from early childhood. Copyright © 2014 Wiley Periodicals, Inc.

Receptive-field subfields of V2 neurons in macaque monkeys are adult-like near birth.

PubMed

Zhang, Bin; Tao, Xiaofeng; Shen, Guofu; Smith, Earl L; Ohzawa, Izumi; Chino, Yuzo M

2013-02-06

Infant primates can discriminate texture-defined form despite their relatively low visual acuity. The neuronal mechanisms underlying this remarkable visual capacity of infants have not been studied in nonhuman primates. Since many V2 neurons in adult monkeys can extract the local features in complex stimuli that are required for form vision, we used two-dimensional dynamic noise stimuli and local spectral reverse correlation to measure whether the spatial map of receptive-field subfields in individual V2 neurons is sufficiently mature near birth to capture local features. As in adults, most V2 neurons in 4-week-old monkeys showed a relatively high degree of homogeneity in the spatial matrix of facilitatory subfields. However, ∼25% of V2 neurons had the subfield map where the neighboring facilitatory subfields substantially differed in their preferred orientations and spatial frequencies. Over 80% of V2 neurons in both infants and adults had "tuned" suppressive profiles in their subfield maps that could alter the tuning properties of facilitatory profiles. The differences in the preferred orientations between facilitatory and suppressive profiles were relatively large but extended over a broad range. Response immaturities in infants were mild; the overall strength of facilitatory subfield responses was lower than that in adults, and the optimal correlation delay ("latency") was longer in 4-week-old infants. These results suggest that as early as 4 weeks of age, the spatial receptive-field structure of V2 neurons is as complex as in adults and the ability of V2 neurons to compare local features of neighboring stimulus elements is nearly adult like.

Hippocampal substructural vulnerability to sleep disturbance and cognitive impairment in patients with chronic primary insomnia: magnetic resonance imaging morphometry.

PubMed

Joo, Eun Yeon; Kim, Hosung; Suh, Sooyeon; Hong, Seung Bong

2014-07-01

Despite compelling evidence from animal studies indicating hippocampal subfield-specific vulnerability to poor sleep quality and related cognitive impairment, there have been no human magnetic resonance imaging (MRI) studies investigating the relationship between hippocampal subfield volume and sleep disturbance. Our aim was to investigate the pattern of volume changes across hippocampal subfields in patients with primary insomnia relative to controls. Pointwise morphometry allowed for volume measurements of hippocampal regions on T1-weighted MRI. University hospital. Twenty-seven unmedicated patients (age: 51.2 ± 9.6 y) and 30 good sleepers as controls (50.4 ± 7.1 y). N/A. We compared hippocampal subfield volumes between patients and controls and correlated volume with clinical and neuropsychological features in patients. Patients exhibited bilateral atrophy across all hippocampal subfields (P < 0.05 corrected). Cornu ammonis (CA) 1 subfield atrophy was associated with worse sleep quality (higher Pittsburgh Sleep Quality Index and higher arousal index of polysomnography) (r < -0.45, P < 0.005). The volume of the combined region, including the dentate gyrus (DG) and CA3-4, negatively correlated with verbal memory, verbal information processing, and verbal fluency in patients (|r| > 0.45, P < 0.05). Hemispheric volume asymmetry of this region (left smaller than right) was associated with impaired verbal domain functions (r = 0.50, P < 0.005). Hippocampal subfield atrophy in chronic insomnia suggests reduced neurogenesis in the dentate gyrus (DG) and neuronal loss in the cornu ammonis (CA) subfields in conditions of sleep fragmentation and related chronic stress condition. Atrophy in the CA3-4-DG region was associated with impaired cognitive functions in patients. These observations may provide insight into pathophysiological mechanisms that make patients with chronic sleep disturbance vulnerable to cognitive impairment. Joo EY, Kim H, Suh S, Hong SB. Hippocampal substructural vulnerability to sleep disturbance and cognitive impairment in patients with chronic primary insomnia: magnetic resonance imaging morphometry.

Thought Experiments in the Theory of Relativity and in Quantum Mechanics: Their Presence in Textbooks and in Popular Science Books

ERIC Educational Resources Information Center

Velentzas, Athanasios; Halkia, Krystallia; Skordoulis, Constantine

2007-01-01

This work investigates the presence of Thought Experiments (TEs) which refer to the theory of relativity and to quantum mechanics in physics textbooks and in books popularizing physics theories. A further point of investigation is whether TEs--as presented in popular physics books--can be used as an introduction to familiarize secondary school…

Jefferson's Views on Education: Implications for Today's Social Studies

ERIC Educational Resources Information Center

Carpenter, James J.

2004-01-01

It is virtually impossible to find a U.S. civics or government textbook that does not cite Thomas Jefferson's faith in a well-educated citizenry as the great defense against tyranny. It is also common to open a U.S. history textbook for middle or high school students and find a reference to Jefferson and the value he put on education. Because the…

A Rational Reconstruction of the Kinetic Molecular Theory of Gases Based on History and Philosophy of Science and Its Implications for Chemistry Textbooks.

ERIC Educational Resources Information Center

Niaz, Mansoor

2000-01-01

Describes a study that was designed to develop a framework for examining the way in which chemistry textbooks describe the kinetic theory and related issues. The framework was developed by a rational reconstruction of the kinetic molecular theory of gases based on historians and philosophers of science. (Contains 102 references.)(Author/LRW)

49 CFR 511.53 - Appeal from initial decision.

Code of Federal Regulations, 2013 CFR

2013-10-01

... position taken on each question, with specific page references to the record and legal or other material... matters in the brief, with page references, and a table of cases (alphabetically arranged), textbooks, statutes, and other material cited, with page references thereto; (2) A concise statement of the case; (3...

49 CFR 511.53 - Appeal from initial decision.

Code of Federal Regulations, 2011 CFR

2011-10-01

... position taken on each question, with specific page references to the record and legal or other material... matters in the brief, with page references, and a table of cases (alphabetically arranged), textbooks, statutes, and other material cited, with page references thereto; (2) A concise statement of the case; (3...

49 CFR 511.53 - Appeal from initial decision.

Code of Federal Regulations, 2010 CFR

2010-10-01

... position taken on each question, with specific page references to the record and legal or other material... matters in the brief, with page references, and a table of cases (alphabetically arranged), textbooks, statutes, and other material cited, with page references thereto; (2) A concise statement of the case; (3...

Risk analysis and timber investments: a bibliography of theory and applications.

Treesearch

Carol A. Hyldahl; David C. Baumgartner

1991-01-01

Contains a fairly complete set of references to the small but rapidly growing amount of literature directly related to the study of risk in forestry in the United States up to 1989. Also includes representative references for the huge literature of general financial theory dealing with risk. Includes 95 annotated references and 17 additional textbook references...

Investigation with respect to content and general properties of physics 10 textbook in accordance with the 2013 secondary school physics curriculum

NASA Astrophysics Data System (ADS)

Kavcar, Nevzat; Korkmaz, Cihan

2017-02-01

Purpose of this work is to determine the physics teacher candidates' views on Physics 10 textbook' content and general properties suitable to the 2013 Secondary School Physics Curriculum. 23 teacher candidates at 2014-2015 school year constituted the sampling of the study in which scanning model based on qualitative research technique was used by performing document analysis. Data collection tool of the research was the files prepared with 51 and nine open ended questions including the subject content and general properties of the textbook. It was concluded that the textbook was sufficient for being life context -based, language, activity-based and student-centered approximation, development of social and inquiry skills, and was insufficient for referring educational gains of the Curriculum, involving activities, projects and homework about application. Activities and applications about affective area, such tools for assessment and evaluation practices as concept map, concept network and semantic analysis table may be involved in the textbook.

Representation of scientific methodology in secondary science textbooks

NASA Astrophysics Data System (ADS)

Binns, Ian C.

The purpose of this investigation was to assess the representation of scientific methodology in secondary science textbooks. More specifically, this study looked at how textbooks introduced scientific methodology and to what degree the examples from the rest of the textbook, the investigations, and the images were consistent with the text's description of scientific methodology, if at all. The sample included eight secondary science textbooks from two publishers, McGraw-Hill/Glencoe and Harcourt/Holt, Rinehart & Winston. Data consisted of all student text and teacher text that referred to scientific methodology. Second, all investigations in the textbooks were analyzed. Finally, any images that depicted scientists working were also collected and analyzed. The text analysis and activity analysis used the ethnographic content analysis approach developed by Altheide (1996). The rubrics used for the text analysis and activity analysis were initially guided by the Benchmarks (AAAS, 1993), the NSES (NRC, 1996), and the nature of science literature. Preliminary analyses helped to refine each of the rubrics and grounded them in the data. Image analysis used stereotypes identified in the DAST literature. Findings indicated that all eight textbooks presented mixed views of scientific methodology in their initial descriptions. Five textbooks placed more emphasis on the traditional view and three placed more emphasis on the broad view. Results also revealed that the initial descriptions, examples, investigations, and images all emphasized the broad view for Glencoe Biology and the traditional view for Chemistry: Matter and Change. The initial descriptions, examples, investigations, and images in the other six textbooks were not consistent. Overall, the textbook with the most appropriate depiction of scientific methodology was Glencoe Biology and the textbook with the least appropriate depiction of scientific methodology was Physics: Principles and Problems. These findings suggest that compared to earlier investigations, textbooks have begun to improve in how they represent scientific methodology. However, there is still much room for improvement. Future research needs to consider how textbooks impact teachers' and students' understandings of scientific methodology.

Book Review

NASA Astrophysics Data System (ADS)

Clevers, J. G. P. W.

2015-02-01

About thirty years after the previous advanced textbook on Microwave Remote Sensing by Ulaby, Moore and Fung has been published as three separate volumes, now an up-to-date new textbook has been published. The 1000-page book covers theoretical models, system design and operation, and geoscientific applications of active and passive microwave remote sensing systems. It is designed as a textbook at the postgraduate level, as well as a reference for the practicing professional. The book is caught by a thorough introduction into the physics and mathematics of electrical engineering applied to microwave radiation. Here on overview of its chapters with a short description of its focus will be given.

Automated hippocampal subfield segmentation at 7 tesla MRI

PubMed Central

Wisse, Laura E.M.; Kuijf, Hugo J.; Honingh, Anita M.; Wang, Hongzhi; Pluta, John B.; Das, Sandhitsu R.; Wolk, David A.; Zwanenburg, Jaco J.M.; Yushkevich, Paul A.; Geerlings, Mirjam I.

2015-01-01

Purpose We aimed to evaluate an automated technique to segment hippocampal subfields and the entorhinal cortex (ERC) at 7 tesla MRI. Materials and Methods Cornu Ammonis (CA)1, CA2, CA3, dentate gyrus (DG), subiculum (SUB) and ERC were manually segmented, covering most of the long axis of the hippocampus, on 0.70 mm3 T2-weighted 7 tesla images of twenty-six participants (59±9 years, 46% men). The Automated Segmentation of Hippocampal Subfields (ASHS) approach was applied and evaluated using leave-one-out cross-validation. Results Comparison of automated segmentations with corresponding manual segmentation yielded a Dice similarity coefficient (DSC) of >0.75 for CA1, DG, SUB and ERC; and >0.54 for CA2 and CA3. Intraclass correlation coefficients (ICC) were >0.74 for CA1, DG and SUB; and >0.43 for CA2, CA3 and the ERC. Restricting the comparison of the ERC segmentation to a smaller range along the anterior-posterior axis improved both ICCs (left: 0.71; right: 0.82) and DSCs (left: 0.78; right: 0.77). The accuracy of ASHS vs a manual rater was lower, though only slightly for most subfields, than the intra-rater reliability of an expert manual rater, but was similar or slightly higher than the accuracy of an expert vs. a manual rater with ~170h of training for almost all subfields. Conclusion This work demonstrates the feasibility of using a computational technique to automatically label hippocampal subfields and the ERC at 7 tesla MRI, with a high accuracy for most subfields that is competitive with the labor intensive manual segmentation. The software and atlas are publicly available: http://www.nitrc.org/projects/ashs/. PMID:26846925

Iranians' contribution to world literature on neuroscience.

PubMed

Ashrafi, Farzad; Mohammadhassanzadeh, Hafez; Shokraneh, Farhad; Valinejadi, Ali; Johari, Karim; Saemi, Nazanin; Zali, Alireza; Mohaghegh, Niloofar; Ashayeri, Hassan

2012-12-01

The purpose of this study is to analyse Iranian scientific publications in the neuroscience subfields by librarians and neuroscientists, using Science Citation Index Expanded (SCIE) via Web of Science data over the period, 2002-2008. Data were retrieved from the SCIE. Data were collected from the 'subject area' of the database and classified by neuroscience experts into 14 subfields. To identify the citation patterns, we applied the 'impact factor' and the 'number of publication'. Data were also analysed using HISTCITE, Excel 2007 and SPSS. Seven hundred and thirty-four papers have been published by Iranian between 2002 and 2008. Findings showed a growing trend of neuroscience papers in the last 3 years with most papers (264) classified in the neuropharmacology subfield. There were fewer papers in neurohistory, psychopharmacology and artificial intelligence. International contributions of authors were mostly in the neurology subfield, and 'Collaboration Coefficient' for the neuroscience subfields in Iran was 0.686 which is acceptable. Most international collaboration between Iranians and developed countries was from USA. Eighty-seven percent of the published papers were in journals with the impact factor between 0 and 4; 25% of papers were published by the researchers affiliated to Tehran University of Medical Sciences. Progress of neuroscience in Iran is mostly seen in the neuropharmacology and the neurology subfields. Other subfields should also be considered as a research priority by health policymakers. As this study was carried out by the collaboration of librarians and neuroscientists, it has been proved valuable for both librarians and policymakers. This study may be encouraging for librarians from other developing countries. © 2012 The authors. Health Information and Libraries Journal © 2012 Health Libraries Group.

The relation of hippocampal subfield volumes to verbal episodic memory measured by the California Verbal Learning Test II in healthy adults.

PubMed

Aslaksen, Per M; Bystad, Martin K; Ørbo, Marte C; Vangberg, Torgil R

2018-06-08

Total hippocampal volume has previously been shown to correlate with performance on tests for verbal episodic memory. However, there are sparse evidence on how hippocampal subfield volumes are related to verbal episodic memory in healthy adults. The present study investigated the association between volumes of separate hippocampal subfields and verbal episodic memory performance in healthy volunteers. Forty-seven participants (31 females) between 20 to 71 years age underwent testing with the California Verbal Learning Test II (CVLT II), and the Wechsler Abbreviated Scale of Intelligence (WASI) to obtain an estimate of cognitive functioning. T1-weighted MR images were obtained after cognitive testing, and volumetric estimates adjusted for age and estimated total intracranial volume were calculated in the FreeSurfer 6.0 software suite for cerebral -and hippocampal structures. The sample performed within the statistical normal range on both CVLT II and WASI. Significant correlations adjusted for multiple testing were found between CVLT II subtests of total learning, free immediate recall and free delayed recall and volumes of the left Cornu Ammonis (CA) 1-4 subfields. There were no significant correlations between right hippocampal subfields and CVLT II performance, and no significant correlation between WASI results and hippocampal subfields. The present results suggest that better verbal episodic memory measured by the CVLT II is associated with relative larger volumes of specific left CA hippocampal subfields in healthy adults. Due to the small sample size and large age-span of the participants, the present findings are preliminary and should be confirmed in larger samples. Copyright © 2018 Elsevier B.V. All rights reserved.

Visual Receptive Field Structure of Cortical Inhibitory Neurons Revealed by Two-Photon Imaging Guided Recording

PubMed Central

Liu, Bao-hua; Li, Pingyang; Li, Ya-tang; Sun, Yujiao J.; Yanagawa, Yuchio; Obata, Kunihiko; Zhang, Li I.; Tao, Huizhong W.

2009-01-01

Synaptic inhibition plays an important role in shaping receptive field (RF) properties in the visual cortex. However, the underlying mechanisms remain not well understood, partly due to difficulties in systematically studying functional properties of cortical inhibitory neurons in vivo. Here, we established two-photon imaging guided cell-attached recordings from genetically labelled inhibitory neurons and nearby “shadowed” excitatory neurons in the primary visual cortex of adult mice. Our results revealed that in layer 2/3, the majority of excitatory neurons exhibited both On and Off spike subfields, with their spatial arrangement varying from being completely segregated to overlapped. On the other hand, most layer 4 excitatory neurons exhibited only one discernable subfield. Interestingly, no RF structure with significantly segregated On and Off subfields was observed for layer 2/3 inhibitory neurons of either the fast-spike or regular-spike type. They predominantly possessed overlapped On and Off subfields with a significantly larger size than the excitatory neurons, and exhibited much weaker orientation tuning. These results from the mouse visual cortex suggest that different from the push-pull model proposed for simple cells, layer 2/3 simple-type neurons with segregated spike On and Off subfields likely receive spatially overlapped inhibitory On and Off inputs. We propose that the phase-insensitive inhibition can enhance the spatial distinctiveness of On and Off subfields through a gain control mechanism. PMID:19710305

Textbook images: how do they invite students into physics?

NASA Astrophysics Data System (ADS)

Bungum, Berit

2013-09-01

This paper presents a study of images in Norwegian physics textbooks for upper secondary school, and how they invite students into physics by means of visual communication. The concept of ‘framing’ is used to investigate how the perspective in the image provides a sense of participation. It is found that older textbooks, where objects and experimental setups dominate the images, involve the reader in terms of weak framing. This is to some degree resembled in newer textbooks with the increased use of photographs of learners in some physics activity. This does, however, invite the learner into school physics rather than professional physics. Connections made to physics in society and everyday life in images can also be seen as inviting the learner into physics, by exhibiting how modern physicists work and by referring to the relevance of physics, respectively.

Regional tau deposition and subregion atrophy of medial temporal structures in early Alzheimer's disease: A combined positron emission tomography/magnetic resonance imaging study.

PubMed

Sone, Daichi; Imabayashi, Etsuko; Maikusa, Norihide; Okamura, Nobuyuki; Furumoto, Shozo; Kudo, Yukitsuka; Ogawa, Masayo; Takano, Harumasa; Yokoi, Yuma; Sakata, Masuhiro; Tsukamoto, Tadashi; Kato, Koichi; Matsuda, Hiroshi

2017-01-01

Molecular imaging and selective hippocampal subfield atrophy are a focus of recent Alzheimer's disease (AD) research. Here, we investigated correlations between molecular imaging and hippocampal subfields in early AD. We investigated 18 patients with early AD and 18 healthy control subjects using 11 C-Pittsburgh compound-B (PIB) positron emission tomography (PET) and 18 F-THK5351 PET and automatic segmentation of hippocampal subfields with high-resolution T2-weighted magnetic resonance imaging. The PET images were normalized and underwent voxelwise regression analysis with each subregion volumes using SPM12. As for 18 F-THK5351 PET, the bilateral perirhinal cortex volumes were significantly associated with the ipsilateral or bilateral temporal lobar uptakes, whereas hippocampal subfields showed no correlations. 11 C-PIB PET showed relatively broad negative correlation with the right cornu ammonis 3 volumes. Regional tau deposition was correlated with extrahippocampal subregional atrophy and not with hippocampal subfields, possibly reflecting different underlying mechanisms of atrophy in early AD. Amyloid might be associated with right cornu ammonis 3 atrophy.

Hippocampal Substructural Vulnerability to Sleep Disturbance and Cognitive Impairment in Patients with Chronic Primary Insomnia: Magnetic Resonance Imaging Morphometry

PubMed Central

Joo, Eun Yeon; Kim, Hosung; Suh, Sooyeon; Hong, Seung Bong

2014-01-01

Study Objectives: Despite compelling evidence from animal studies indicating hippocampal subfield-specific vulnerability to poor sleep quality and related cognitive impairment, there have been no human magnetic resonance imaging (MRI) studies investigating the relationship between hippocampal subfield volume and sleep disturbance. Our aim was to investigate the pattern of volume changes across hippocampal subfields in patients with primary insomnia relative to controls. Design: Pointwise morphometry allowed for volume measurements of hippocampal regions on T1-weighted MRI. Setting: University hospital. Patients: Twenty-seven unmedicated patients (age: 51.2 ± 9.6 y) and 30 good sleepers as controls (50.4 ± 7.1 y). Interventions: N/A. Measurements: We compared hippocampal subfield volumes between patients and controls and correlated volume with clinical and neuropsychological features in patients. Results: Patients exhibited bilateral atrophy across all hippocampal subfields (P < 0.05 corrected). Cornu ammonis (CA) 1 subfield atrophy was associated with worse sleep quality (higher Pittsburgh Sleep Quality Index and higher arousal index of polysomnography) (r < -0.45, P < 0.005). The volume of the combined region, including the dentate gyrus (DG) and CA3-4, negatively correlated with verbal memory, verbal information processing, and verbal fluency in patients (|r| > 0.45, P < 0.05). Hemispheric volume asymmetry of this region (left smaller than right) was associated with impaired verbal domain functions (r = 0.50, P < 0.005). Conclusion: Hippocampal subfield atrophy in chronic insomnia suggests reduced neurogenesis in the dentate gyrus (DG) and neuronal loss in the cornu ammonis (CA) subfields in conditions of sleep fragmentation and related chronic stress condition. Atrophy in the CA3-4-DG region was associated with impaired cognitive functions in patients. These observations may provide insight into pathophysiological mechanisms that make patients with chronic sleep disturbance vulnerable to cognitive impairment. Citation: Joo EY, Kim H, Suh S, Hong SB. Hippocampal substructural vulnerability to sleep disturbance and cognitive impairment in patients with chronic primary insomnia: magnetic resonance imaging morphometry. SLEEP 2014;37(7):1189-1198. PMID:25061247

32 CFR 199.21 - Pharmacy benefits program.

Code of Federal Regulations, 2010 CFR

2010-07-01

... information may include but are not limited to: (A) Medical and pharmaceutical textbooks and reference books... Book) published by the Food and Drug Administration, or any successor to such reference. Generics are...) Cross-sectional or retrospective economic evaluations; (F) Pharmacoeconomic models; (G) Patent...

Local sensitivity to stimulus orientation and spatial frequency within the receptive fields of neurons in visual area 2 of macaque monkeys

PubMed Central

Tao, X.; Zhang, B.; Smith, E. L.; Nishimoto, S.; Ohzawa, I.

2012-01-01

We used dynamic dense noise stimuli and local spectral reverse correlation methods to reveal the local sensitivities of neurons in visual area 2 (V2) of macaque monkeys to orientation and spatial frequency within their receptive fields. This minimized the potentially confounding assumptions that are inherent in stimulus selections. The majority of neurons exhibited a relatively high degree of homogeneity for the preferred orientations and spatial frequencies in the spatial matrix of facilitatory subfields. However, about 20% of all neurons showed maximum orientation differences between neighboring subfields that were greater than 25 deg. The neurons preferring horizontal or vertical orientations showed less inhomogeneity in space than the neurons preferring oblique orientations. Over 50% of all units also exhibited suppressive profiles, and those were more heterogeneous than facilitatory profiles. The preferred orientation and spatial frequency of suppressive profiles differed substantially from those of facilitatory profiles, and the neurons with suppressive subfields had greater orientation selectivity than those without suppressive subfields. The peak suppression occurred with longer delays than the peak facilitation. These results suggest that the receptive field profiles of the majority of V2 neurons reflect the orderly convergence of V1 inputs over space, but that a subset of V2 neurons exhibit more complex response profiles having both suppressive and facilitatory subfields. These V2 neurons with heterogeneous subfield profiles could play an important role in the initial processing of complex stimulus features. PMID:22114163

The extent to which core nursing textbooks inform holistic spiritual care.

PubMed

Timmins, Fiona; Murphy, Maryanne; Begley, Thelma; Neill, Freda; Sheaf, Greg

2016-09-01

National and international professional health and nursing guidelines recommend that attention should be given to the spiritual and religious needs of patients. This suggests that spiritual care is an important aspect of holistic patient care that needs to be considered and supported, if relevant, in a healthcare context. However, many nurses lack knowledge and awareness of the subject, and it is unclear to what extent core textbooks provide the information they need. This article reports on a study that explored the extent to which contemporary core nursing textbooks support and advocate the provision of spiritual care by nurses. Its findings suggest there is a lack of consistency in the inclusion of spirituality in these texts, and few refer specifically to the need for spiritual assessment tools or referral to chaplains. As more attention is given to patients' spiritual needs, the guidance given by nursing textbooks needs to be more substantive and consistent.

Discussion of death and dying in surgical textbooks.

PubMed

Easson, A M; Crosby, J A; Librach, S L

2001-07-01

Quality end-of-life care is an increasing concern for the public and the medical profession. Surgical textbooks could serve as an important educational and reference resource to improve this care. Four general surgical textbooks were scored for helpful information on death and dying for eight surgical diseases. For each disease, nine content domains related to care of the dying patient were evaluated. Three texts included a chapter on cancer that was evaluated separately. Disease epidemiology, prognosis/prevention, progression, and medical interventions were generally well discussed in all textbooks. However, little helpful information was provided with regards to breaking bad news/advanced care planning, mode of death, treatment decision-making, effect on family/surgeon, and symptom management. Cancer chapters also addressed only a few of these concerns. Death and the dying patient are sufficiently frequent in surgical practice that it would be appropriate to increase the amount of information provided.

Subfield-specific loss of hippocampal N-acetyl aspartate in temporal lobe epilepsy.

PubMed

Vielhaber, Stefan; Niessen, Heiko G; Debska-Vielhaber, Grazyna; Kudin, Alexei P; Wellmer, Jörg; Kaufmann, Jörn; Schönfeld, Mircea Ariel; Fendrich, Robert; Willker, Wieland; Leibfritz, Dieter; Schramm, Johannes; Elger, Christian E; Heinze, Hans-Jochen; Kunz, Wolfram S

2008-01-01

In patients with mesial temporal lobe epilepsy (MTLE) it remains an unresolved issue whether the interictal decrease in N-acetyl aspartate (NAA) detected by proton magnetic resonance spectroscopy ((1)H-MRS) reflects the epilepsy-associated loss of hippocampal pyramidal neurons or metabolic dysfunction. To address this problem, we applied high-resolution (1)H-MRS at 14.1 Tesla to measure metabolite concentrations in ex vivo tissue slices from three hippocampal subfields (CA1, CA3, dentate gyrus) as well as from the parahippocampal region of 12 patients with MTLE. In contrast to four patients with lesion-caused MTLE, we found a large variance of NAA concentrations in the individual hippocampal regions of patients with Ammon's horn sclerosis (AHS). Specifically, in subfield CA3 of AHS patients despite of a moderate preservation of neuronal cell densities the concentration of NAA was significantly lowered, while the concentrations of lactate, glucose, and succinate were elevated. We suggest that these subfield-specific alterations of metabolite concentrations in AHS are very likely caused by impairment of mitochondrial function and not related to neuronal cell loss. A subfield-specific impairment of energy metabolism is the probable cause for lowered NAA concentrations in sclerotic hippocampi of MTLE patients.

Evaluation of ex-vivo 9.4T MRI in post-surgical specimens from temporal lobe epilepsy patients.

PubMed

Kwan, Benjamin Y M; Salehi, Fateme; Kope, Ryan; Lee, Donald H; Sharma, Manas; Hammond, Robert; Burneo, Jorge G; Steven, David; Peters, Terry; Khan, Ali R

2017-10-01

This study evaluates hippocampal pathology through usage of ultra-high field 9.4T ex-vivo imaging of resected surgical specimens in patients who have undergone temporal lobe epilepsy surgery. This is a retrospective interpretation of prospectively acquired data. MRI scanning of resected surgical specimens from patients who have undergone temporal lobe epilepsy surgery was performed on a 9.4T small bore Varian MR magnet. Structural images employed a balanced steady-state free precession sequence (TrueFISP). Six patients (3 females; 3 males) were included in this study with an average age at surgery of 40.7 years (range 20Y_"60) (one was used as a control reference). Two neuroradiologists qualitatively reviewed the ex-vivo MRIs of resected specimens while blinded to the histopathology reports for the ability to identify abnormal features in hippocampal subfield structures. The hippocampal subfields were reliably identified on the 9.4T ex-vivo scans in the hippocampal head region and hippocampal body region by both neuroradiologists in all 6 patients. There was high concordance to pathology for abnormalities detected in the CA1, CA2, CA3 and CA4 subfields. Detection of abnormalities in the dentate gyrus was also high with detection in 4 of 5 cases. The Cohen's kappa between the two neuroradiologists was calculated at 0.734 SE=0.102. Ex-vivo 9.4T specimen imaging can detect abnormalities in CA1, CA2, CA3, CA4 and DG in both the hippocampal head and body. There was good concordance between qualitative findings and histopathological abnormalities for CA1, CA2, CA3, CA4 and DG. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Posttraumatic Stress Disorder and Depression Symptom Severities Are Differentially Associated With Hippocampal Subfield Volume Loss in Combat Veterans.

PubMed

Averill, Christopher L; Satodiya, Ritvij M; Scott, J Cobb; Wrocklage, Kristen M; Schweinsburg, Brian; Averill, Lynnette A; Akiki, Teddy J; Amoroso, Timothy; Southwick, Steven M; Krystal, John H; Abdallah, Chadi G

2017-01-01

Two decades of human neuroimaging research have associated volume reductions in the hippocampus with posttraumatic stress disorder. However, little is known about the distribution of volume loss across hippocampal subfields. Recent advances in neuroimaging methods have made it possible to accurately delineate 10 gray matter hippocampal subfields. Here, we apply a volumetric analysis of hippocampal subfields to data from a group of combat-exposed Veterans. Veterans (total, n = 68, posttraumatic stress disorder, n = 36; combat control, n = 32) completed high-resolution structural magnetic resonance imaging. Based on previously validated methods, hippocampal subfield volume measurements were conducted using FreeSurfer 6.0. The Clinician-Administered PTSD Scale assessed posttraumatic stress disorder symptom severity; Beck Depression Inventory assessed depressive symptom severity. Controlling for age and intracranial volume, partial correlation analysis examined the relationship between hippocampal subfields and symptom severity. Correction for multiple comparisons was performed using false discovery rate. Gender, intelligence, combat severity, comorbid anxiety, alcohol/substance use disorder, and medication status were investigated as potential confounds. In the whole sample, total hippocampal volume negatively correlated with Clinician-Administered PTSD Scale and Beck Depression Inventory scores. Of the 10 hippocampal subfields, Clinician-Administered PTSD Scale symptom severity negatively correlated with the hippocampus-amygdala transition area (HATA). Beck Depression Inventory scores negatively correlated with dentate gyrus, cornu ammonis 4 (CA4), HATA, CA2/3, molecular layer, and CA1. Follow-up analysis limited to the posttraumatic stress disorder group showed a negative correlation between Clinician-Administered PTSD Scale symptom severity and each of HATA, CA2/3, molecular layer, and CA4. This study provides the first evidence relating posttraumatic stress disorder and depression symptoms to abnormalities in the HATA, an anterior hippocampal region highly connected to prefrontal-amygdala circuitry. Notably, dentate gyrus abnormalities were associated with depression severity but not posttraumatic stress disorder symptoms. Future confirmatory studies should determine the extent to which dentate gyrus volume can differentiate between posttraumatic stress disorder- and depression-related pathophysiology.

Hippocampal subfield surface deformity in non-semantic primary progressive aphasia.

PubMed

Christensen, Adam; Alpert, Kathryn; Rogalski, Emily; Cobia, Derin; Rao, Julia; Beg, Mirza Faisal; Weintraub, Sandra; Mesulam, M-Marsel; Wang, Lei

2015-03-01

Alzheimer neuropathology (AD) is found in almost half of patients with non-semantic primary progressive aphasia (PPA). This study examined hippocampal abnormalities in PPA to determine similarities to those described in amnestic AD. In 37 PPA patients and 32 healthy controls, we generated hippocampal subfield surface maps from structural MRIs and administered a face memory test. We analyzed group and hemisphere differences for surface shape measures and their relationship with test scores and ApoE genotype. The hippocampus in PPA showed inward deformity (CA1 and subiculum subfields) and outward deformity (CA2-4+DG subfield) and smaller left than right volumes. Memory performance was related to hippocampal shape abnormalities in PPA patients, but not controls, even in the absence of memory impairments. Hippocampal deformity in PPA is related to memory test scores. This may reflect a combination of intrinsic degenerative phenomena with transsynaptic or Wallerian effects of neocortical neuronal loss.

The evolution of interdisciplinarity in physics research.

PubMed

Pan, Raj Kumar; Sinha, Sitabhra; Kaski, Kimmo; Saramäki, Jari

2012-01-01

Science, being a social enterprise, is subject to fragmentation into groups that focus on specialized areas or topics. Often new advances occur through cross-fertilization of ideas between sub-fields that otherwise have little overlap as they study dissimilar phenomena using different techniques. Thus to explore the nature and dynamics of scientific progress one needs to consider the organization and interactions between different subject areas. Here, we study the relationships between the sub-fields of Physics using the Physics and Astronomy Classification Scheme (PACS) codes employed for self-categorization of articles published over the past 25 years (1985-2009). We observe a clear trend towards increasing interactions between the different sub-fields. The network of sub-fields also exhibits core-periphery organization, the nucleus being dominated by Condensed Matter and General Physics. However, over time Interdisciplinary Physics is steadily increasing its share in the network core, reflecting a shift in the overall trend of Physics research.

Accuracy and Completeness of Drug Information in Wikipedia: A Comparison with Standard Textbooks of Pharmacology

PubMed Central

Gutmann, Joanna; Muehlich, Susanne; Zolk, Oliver; Wojnowski, Leszek; Maas, Renke; Engelhardt, Stefan; Sarikas, Antonio

2014-01-01

The online resource Wikipedia is increasingly used by students for knowledge acquisition and learning. However, the lack of a formal editorial review and the heterogeneous expertise of contributors often results in skepticism by educators whether Wikipedia should be recommended to students as an information source. In this study we systematically analyzed the accuracy and completeness of drug information in the German and English language versions of Wikipedia in comparison to standard textbooks of pharmacology. In addition, references, revision history and readability were evaluated. Analysis of readability was performed using the Amstad readability index and the Erste Wiener Sachtextformel. The data on indication, mechanism of action, pharmacokinetics, adverse effects and contraindications for 100 curricular drugs were retrieved from standard German textbooks of general pharmacology and compared with the corresponding articles in the German language version of Wikipedia. Quantitative analysis revealed that accuracy of drug information in Wikipedia was 99.7%±0.2% when compared to the textbook data. The overall completeness of drug information in Wikipedia was 83.8±1.5% (p<0.001). Completeness varied in-between categories, and was lowest in the category “pharmacokinetics” (68.0%±4.2%; p<0.001) and highest in the category “indication” (91.3%±2.0%) when compared to the textbook data overlap. Similar results were obtained for the English language version of Wikipedia. Of the drug information missing in Wikipedia, 62.5% was rated as didactically non-relevant in a qualitative re-evaluation study. Drug articles in Wikipedia had an average of 14.6±1.6 references and 262.8±37.4 edits performed by 142.7±17.6 editors. Both Wikipedia and textbooks samples had comparable, low readability. Our study suggests that Wikipedia is an accurate and comprehensive source of drug-related information for undergraduate medical education. PMID:25250889

Accuracy and completeness of drug information in Wikipedia: a comparison with standard textbooks of pharmacology.

PubMed

Kräenbring, Jona; Monzon Penza, Tika; Gutmann, Joanna; Muehlich, Susanne; Zolk, Oliver; Wojnowski, Leszek; Maas, Renke; Engelhardt, Stefan; Sarikas, Antonio

2014-01-01

The online resource Wikipedia is increasingly used by students for knowledge acquisition and learning. However, the lack of a formal editorial review and the heterogeneous expertise of contributors often results in skepticism by educators whether Wikipedia should be recommended to students as an information source. In this study we systematically analyzed the accuracy and completeness of drug information in the German and English language versions of Wikipedia in comparison to standard textbooks of pharmacology. In addition, references, revision history and readability were evaluated. Analysis of readability was performed using the Amstad readability index and the Erste Wiener Sachtextformel. The data on indication, mechanism of action, pharmacokinetics, adverse effects and contraindications for 100 curricular drugs were retrieved from standard German textbooks of general pharmacology and compared with the corresponding articles in the German language version of Wikipedia. Quantitative analysis revealed that accuracy of drug information in Wikipedia was 99.7% ± 0.2% when compared to the textbook data. The overall completeness of drug information in Wikipedia was 83.8 ± 1.5% (p < 0.001). Completeness varied in-between categories, and was lowest in the category "pharmacokinetics" (68.0% ± 4.2%; p < 0.001) and highest in the category "indication" (91.3% ± 2.0%) when compared to the textbook data overlap. Similar results were obtained for the English language version of Wikipedia. Of the drug information missing in Wikipedia, 62.5% was rated as didactically non-relevant in a qualitative re-evaluation study. Drug articles in Wikipedia had an average of 14.6 ± 1.6 references and 262.8 ± 37.4 edits performed by 142.7 ± 17.6 editors. Both Wikipedia and textbooks samples had comparable, low readability. Our study suggests that Wikipedia is an accurate and comprehensive source of drug-related information for undergraduate medical education.

Is Textbook Obsolete in New Education? A Critical Analysis on the Value of Textbook in an Inquiry Curriculum, with Special Reference to the New Primary General Studies Curriculum in Hong Kong

ERIC Educational Resources Information Center

Angus, Chan Hok

2004-01-01

The new Primary General Studies (GS) is a landmark of the curriculum reform in Hong Kong. Since year 2001 the local education authority launched the curriculum reform by issuing the "learning to learn" (CDC 2001) document, the curriculum of almost all subjects have been amended or even totally revised to fulfill the spirit of the new…

Fraud Education for Accounting Students.

ERIC Educational Resources Information Center

Peterson, Bonita K.

2003-01-01

Reports that limited fraud education takes place in accounting due to a crowded curriculum and misunderstanding of the extent of fraud. Suggests ways to develop content on the topic and provides a list of teaching materials (textbooks, workbooks, trade books, case materials, videos, and reference materials). (Contains 16 references.) (SK)

Hippocampal subfield volume changes in subtypes of attention deficit hyperactivity disorder.

PubMed

Al-Amin, Mamun; Zinchenko, Artyom; Geyer, Thomas

2018-04-15

Attention-deficit hyperactivity disorder (ADHD) is accompanied by reduction of total hippocampal volume. However, disorder-related fine-grained structural alterations of hippocampal subfields remain unclear. Here we compared hippocampal subfield volumes in a large sample of patients with ADHD and healthy controls. We used T1-weighted structural 3-Tesla MRI images of 880 individuals (7-21 years old) from the ADHD-200 database. The images were acquired from 553 healthy individuals and 327 children and adolescents with combined (N = 196) and inattentive (N = 131) ADHD subtypes. Hippocampal subfields were segmented into the cornu amonis regions (CA1, CA2/3, CA4), fimbria, hippocampal fissure, presubiculum, subiculum, hippocampal tail, parasubiculum, granule cell layers of the dentate gyrus, molecular layer within the subiculum and the CA fields, and the hippocampal-amygdala transition area using an automatic algorithm available in Freesurfer 6.0. We found a significant reduction of total hippocampal volume in the combined ADHD group compared to healthy controls. This reduction was due to the atrophy of CA1, CA4, molecular layer, granule cell layers of the dentate gyrus, presubiculum, subiculum, and hippocampal tail. These differences were exclusively driven by the corresponding brain volume reduction in the combined ADHD-subtype, while hippocampal volumes in inattentive ADHD showed no reliable differences relative to controls. Finally, there were negative correlations between the reduced hippocampal subfields and behavioral ADHD indices. The present results point to a clear dissociation between inattentive and combined subtypes of ADHD. Therefore, hippocampal subfields may contribute towards understanding the pathophysiology of ADHD. Copyright © 2018 Elsevier B.V. All rights reserved.

Spatiotemporal profiles of receptive fields of neurons in the lateral posterior nucleus of the cat LP-pulvinar complex.

PubMed

Piché, Marilyse; Thomas, Sébastien; Casanova, Christian

2015-10-01

The pulvinar is the largest extrageniculate thalamic visual nucleus in mammals. It establishes reciprocal connections with virtually all visual cortexes and likely plays a role in transthalamic cortico-cortical communication. In cats, the lateral posterior nucleus (LP) of the LP-pulvinar complex can be subdivided in two subregions, the lateral (LPl) and medial (LPm) parts, which receive a predominant input from the striate cortex and the superior colliculus, respectively. Here, we revisit the receptive field structure of LPl and LPm cells in anesthetized cats by determining their first-order spatiotemporal profiles through reverse correlation analysis following sparse noise stimulation. Our data reveal the existence of previously unidentified receptive field profiles in the LP nucleus both in space and time domains. While some cells responded to only one stimulus polarity, the majority of neurons had receptive fields comprised of bright and dark responsive subfields. For these neurons, dark subfields' size was larger than that of bright subfields. A variety of receptive field spatial organization types were identified, ranging from totally overlapped to segregated bright and dark subfields. In the time domain, a large spectrum of activity overlap was found, from cells with temporally coinciding subfield activity to neurons with distinct, time-dissociated subfield peak activity windows. We also found LP neurons with space-time inseparable receptive fields and neurons with multiple activity periods. Finally, a substantial degree of homology was found between LPl and LPm first-order receptive field spatiotemporal profiles, suggesting a high integration of cortical and subcortical inputs within the LP-pulvinar complex. Copyright © 2015 the American Physiological Society.

[Palliative medicine content in German-language medical textbooks].

PubMed

Becker, G; Dausch, V; Xander, C; Olschewski, M; Momm, F; Blum, H E

2007-02-09

There is a need for improved end-of-life care, especially in the light of demographic changes with an increased incidence of cancer. Although medical textbooks are central to the training of medical students and also serve as a reference for more experienced clinicians, only few data exist on the extent to which medical textbooks address end-of-life care. We analysed the quantity and quality of information on end-of-life care given in German textbooks on different medical disciplines. 26 top-selling German medical textbooks were analysed for the presentation of end-of-life care in chapters that address the 13 most common causes of death worldwide In the 159 chapters analysed for information on traditional topics, like risk factors or early diagnosis (group A), such information was provided in 52% compared with only 9% on end-of-life topics, such as symptom management or manner of death (group B) (p=0.0001). There was no statistically significant difference between the different medical specialities (p=0.22). Line-by-line analysis showed that the phrase death or related terms was mentioned in only 57 of 159 chapters dealing with the most common causes of death worldwide. The top-selling German textbooks that were analysed generally offer little helpful information on end-of-life care of patients.

16 CFR 3.52 - Appeal from initial decision.

Code of Federal Regulations, 2013 CFR

2013-01-01

... the position taken on each question, with specific page references to the record and the legal or... decision. The notice shall specify the party or parties against whom the appeal is taken and shall..., with page references, and a table of cases (alphabetically arranged), textbooks, statutes, and other...

16 CFR 3.52 - Appeal from initial decision.

Code of Federal Regulations, 2014 CFR

2014-01-01

... the position taken on each question, with specific page references to the record and the legal or... decision. The notice shall specify the party or parties against whom the appeal is taken and shall..., with page references, and a table of cases (alphabetically arranged), textbooks, statutes, and other...

Science Books, Volume 9 Number 1.

ERIC Educational Resources Information Center

Wolff, Kathryn, Ed.

This quarterly journal reviews trade books, textbooks, and reference works in the pure and applied sciences for students in elementary and secondary schools and in the first two years of college. Included are selected advanced and professional books useful for reference by students and faculty members. A listing of detailed subject fields is…

Science Books: A Quarterly Review, Volume 5 Number 3.

ERIC Educational Resources Information Center

Deason, Hilary J.

This publication reviews tradebooks, textbooks, and reference works in the pure and applied sciences for students in the elementary schools, secondary schools, and in the first two years of college. Included are selected advanced and professional books useful for reference by students and faculty members. Evaluations and annotations of books…

Science Books, Volume 10 Number 1.

ERIC Educational Resources Information Center

Wolff, Kathryn, Ed.

This quarterly journal reviews trade books, textbooks, and reference works in the pure and applied sciences for students in elementary and secondary schools and in the first two year of college. Included are selected advanced and professional books useful for reference by students and faculty members. A listing of detailed subject fields is…

Science Books: A Quarterly Review, Volume 8, Number 4.

ERIC Educational Resources Information Center

American Association for the Advancement of Science, Washington, DC.

This quarterly journal reviews trade books, textbooks, and reference works in the pure and applied sciences for students in kindergartens, elementary schools, secondary schools, and in the first two years of college. Also included are selected advanced and professional books useful for reference by students and faculty members. Annotations are…

A Guide to Instructional Resources for Consumers' Education.

ERIC Educational Resources Information Center

Johnston, William L.; Greenspan, Nancy B.

This annotated bibliography lists 295 selected instructional references, resources, and teaching aids for consumer education. It includes a variety of both print and nonprint materials, such as films, filmstrips, multimedia kits, games and learning packages for classroom and group instruction, textbooks for all age levels, and references for both…

The Myth of "Scientific Method" in Contemporary Educational Research

ERIC Educational Resources Information Center

Rowbottom, Darrell Patrick; Aiston, Sarah Jane

2006-01-01

Whether educational research should employ the "scientific method" has been a recurring issue in its history. Hence, textbooks on research methods continue to perpetuate the idea that research students ought to choose between competing camps: "positivist" or "interpretivist". In reference to one of the most widely referred to educational research…

Virtual library

NASA Astrophysics Data System (ADS)

Carlowicz, Michael

If you have a computer and a grasp of algebra, you can learn physics. That is one of the messages behind the release of Physics—The Root Science, a new full-text version of a physics textbook available at no cost on the World Wide Web.The interactive textbook is the work of the International Institute of Theoretical and Applied Physics (IITAP) at Iowa State University, which was established in 1993 as a partnership with the United Nations Education, Scientific, and Cultural Organization (UNESCO). With subject matter equivalent to that of a 400-page volume, the text is designed to be completed in one school year. The textbook also will eventually include video clips of experiments and interactive learning modules, as well as links to appropriate cross-references about fundamental principles of physics.

Uncovering racial bias in nursing fundamentals textbooks.

PubMed

Byrne, M M

2001-01-01

This article describes research that sought to identify and critique selected content areas from three nursing fundamentals textbooks for the presence or absence of racial bias embedded in the portrayal of African Americans. The analyzed content areas were the history of nursing, cultural content, and physical assessment/hygiene parameters. A researcher-developed guide was used for data collection and analysis of textual language, illustrations, linguistics, and references. A thematic analysis resulted in I I themes reflecting the portrayal of African Americans in these sampled textbooks. An interpretive analysis with a lens of Sadker and Sadker's categories of bias, along with other literary and theoretical contexts, were used to explore for the presence or absence of racial bias. Recommendations for nursing education are provided.

Women and Minorities in Psychology.

ERIC Educational Resources Information Center

Russo, Nancy Felipe; And Others

1981-01-01

Presents data on women and minorities in the field of psychology in terms of representation, subfields, degree level, experience, licensure/certification, employment status, employment setting, income, and membership in graduate psychology faculty. Discusses continuing underrepresentation of minorities and pervasive subfield segregation and pay…

Almost Ten Years Later: An Analysis of Ethnic Inclusion in Public Relations Textbooks and Reference Books for the Years 1991-1997 as Compared to Kern-Foxworth's Analysis of Books for the Years 1979-1988.

ERIC Educational Resources Information Center

Hannon, Sandra Wills

A study examined the contents of 18 public relations textbooks published between 1991-1997 to determine the quality of minority inclusion. Results indicated that, of the 8,071 pages examined, 97 pages included minorities. Findings suggest that the results of this study were not significantly different from those of a similar, earlier study of…

Fundamentals of Modeling, Data Assimilation, and High-performance Computing

NASA Technical Reports Server (NTRS)

Rood, Richard B.

2005-01-01

This lecture will introduce the concepts of modeling, data assimilation and high- performance computing as it relates to the study of atmospheric composition. The lecture will work from basic definitions and will strive to provide a framework for thinking about development and application of models and data assimilation systems. It will not provide technical or algorithmic information, leaving that to textbooks, technical reports, and ultimately scientific journals. References to a number of textbooks and papers will be provided as a gateway to the literature.

Essential books for health workers in the Third World.

PubMed

Weitzel, R

1992-01-01

Some of the issues relating to access to medical reference information in developing countries is delineated: the selection of core collections, title selection, funding, and accommodation, supervision, and use of collections. Provision of medical textbooks has been ignored in the movement after Alma Ata to strengthen primary health care. Now that the infrastructures are partially in place there is need to improve the availability of medical information. In developing countries, information and communication systems outside cities are problematic. Library extension services in rural areas are limited and the needs are case related. Health care facilities need carefully selected textbooks and manuals: core collections. The experiences in Zimbabwe resulted in the selection of several core lists: 40 references and manuals for hospitals, and 13 textbooks for health center staff. There are economic constraints when a standard European or American medical textbook costs $85 and a nursing textbook $45 and the need, as in the case of Zimbabwe, requires collections for 1000 health care facilities. The source of supply in Zimbabwe and Malawi was the British Council's Educational Law-price Book Scheme, "Teaching Aids at Low Cost." Rural health manuals were available at low cost from the African Medical and Research Foundation. WHO also provides core materials on suitable topics at low prices and availability in several major languages. Other factors besides cost in the selection involve appropriateness to local disease patterns, geographical and environmental characteristics, and the composition and level of the health community. Journals should be included. In Zimbabwe a joint effort was made for core selection by Ministry of Health senior members in the Division of Health Manpower Development and Health Education, 3 medical librarians, a faculty members of the University of Zimbabwe, and advice from several district hospital physicians In Malawi, selection was made by the Ministry of Health and then distributed for comment. Government requires help in funding. Space needs to made available for free accessibility of materials. A staff member should be in charge of the use and intactness of the collection but staff should satisfy their own needs. Rural staff may need to be educated on the importance of use of reference materials.

Analysis of References on the Plastic Surgery In-Service Training Exam.

PubMed

Silvestre, Jason; Zhang, Alicia; Lin, Samuel J

2016-06-01

The Plastic Surgery In-Service Training Exam is a knowledge assessment tool widely used during plastic surgery training in the United States. This study analyzed literature supporting correct answer choices to determine highest yield sources, journal publication lag, and journal impact factors. Digital syllabi of 10 consecutive Plastic Surgery In-Service Training Exam administrations (2006 to 2015) were reviewed. The most-referenced articles, journals, and textbooks were determined. Mean journal impact factor and publication lag were calculated and differences were elucidated by section. Two thousand questions and 5386 references were analyzed. From 2006 to 2015, the percentage of journal citations increased, whereas textbook references decreased (p < 0.001). Plastic and Reconstructive Surgery was cited with greatest frequency (38.5 percent), followed by Clinics in Plastic Surgery (5.6 percent), Journal of Hand Surgery (American volume) (5.1 percent), and Annals of Plastic Surgery (3.8 percent). There was a trend toward less publication lag over the study period (p = 0.05), with a mean publication lag of 9.1 ± 9.0 years for all journal articles. Mean journal impact factor was 2.3 ± 4.3 and lowest for the hand and lower extremity section (1.7 ± 2.8; p < 0.001). The highest yield textbooks were elucidated by section. Plastic surgery faculty and residents may use these data to facilitate knowledge acquisition during residency.

Resource Letter PCP-1: Pre-college Physics Curriculum Materials

ERIC Educational Resources Information Center

Paldy, Lester G.; Swartz, Clifford E.

1973-01-01

Presents a guide to 101 physics curriculum materials including improvement projects and related articles, reference books, commonly used textbooks, teaching aids, and science education periodicals. (CC)

Pulse

MedlinePlus

... to take your wrist pulse References Bernstein D. History and physical examination. In: Kliegman RM, Stanton BF, St. Geme JW, Schor NF, eds. Nelson Textbook of Pediatrics . 20th ed. Philadelphia, PA: Elsevier; 2016: ...

Major depressive episodes over the course of 7 years and hippocampal subfield volumes at 7 tesla MRI: the PREDICT-MR study.

PubMed

Wisse, L E M; Biessels, G J; Stegenga, B T; Kooistra, M; van der Veen, P H; Zwanenburg, J J M; van der Graaf, Y; Geerlings, M I

2015-04-01

Smaller hippocampal volumes have been associated with major depressive disorder (MDD). The hippocampus consists of several subfields that may be differentially related to MDD. We investigated the association of occurrence of major depressive episodes (MDEs), assessed five times over seven years, with hippocampal subfield and entorhinal cortex volumes at 7 tesla MRI. In this prospective study of randomly selected general practice attendees, MDEs according to DSM-IV-R criteria were assessed at baseline and after 6, 12, 39 and 84 months follow-up. At the last follow-up, a T2 (0.7 mm(3)) 7 tesla MRI scan was obtained in 47 participants (60±10 years). The subiculum, cornu ammonis (CA) 1 to 3, dentate gyrus&CA4 and entorhinal cortex volumes were manually segmented according a published protocol. Of the 47 participants, 13 had one MDE and 5 had multiple MDEs. ANCOVAs, adjusted for age, sex, education and intracranial volume, revealed no significant differences in hippocampal subfield or entorhinal cortex volumes between participants with and without an MDE in the preceding 84 months. Multiple episodes were associated with smaller subiculum volumes (B=-0.03 mL/episode; 95% CI -0.06; -0.003), but not with the other hippocampal subfield volumes, entorhinal cortex, or total hippocampal volume. A limitation of this study is the small sample size which makes replication necessary. In this exploratory study, we found that an increasing number of major depressive episodes was associated with smaller subiculum volumes in middle-aged and older persons, but not with smaller volumes in other hippocampal subfields or the entorhinal cortex. Copyright © 2014 Elsevier B.V. All rights reserved.

Glossary of Higher Education Corruption with Explanations

ERIC Educational Resources Information Center

Osipian, Ararat L.

2009-01-01

Higher education corruption is an emerging sub-field of research that has yet to develop its terminological apparatus and own specific research methodologies. The interdisciplinary nature of this sub-field predetermines its dependency on other well-established fields, such as microeconomics, organizational theory, political economy, education…

HIPS: A new hippocampus subfield segmentation method.

PubMed

Romero, José E; Coupé, Pierrick; Manjón, José V

2017-12-01

The importance of the hippocampus in the study of several neurodegenerative diseases such as Alzheimer's disease makes it a structure of great interest in neuroimaging. However, few segmentation methods have been proposed to measure its subfields due to its complex structure and the lack of high resolution magnetic resonance (MR) data. In this work, we present a new pipeline for automatic hippocampus subfield segmentation using two available hippocampus subfield delineation protocols that can work with both high and standard resolution data. The proposed method is based on multi-atlas label fusion technology that benefits from a novel multi-contrast patch match search process (using high resolution T1-weighted and T2-weighted images). The proposed method also includes as post-processing a new neural network-based error correction step to minimize systematic segmentation errors. The method has been evaluated on both high and standard resolution images and compared to other state-of-the-art methods showing better results in terms of accuracy and execution time. Copyright © 2017 Elsevier Inc. All rights reserved.

Increased hippocampal CA1 cerebral blood volume in schizophrenia

PubMed Central

Talati, Pratik; Rane, Swati; Kose, Samet; Blackford, Jennifer Urbano; Gore, John; Donahue, Manus J.; Heckers, Stephan

2014-01-01

Hippocampal hyperactivity has been proposed as a biomarker in schizophrenia. However, there is a debate whether the CA1 or the CA2/3 subfield is selectively affected. We studied 15 schizophrenia patients and 15 matched healthy control subjects with 3T steady state, gadolinium-enhanced, absolute cerebral blood volume (CBV) maps, perpendicular to the long axis of the hippocampus. The subfields of the hippocampal formation (subiculum, CA1, CA2/3, and hilus/dentate gyrus) were manually segmented to establish CBV values. Comparing anterior CA1 and CA2/3 CBV between patients and controls revealed a significant subfield-by-diagnosis interaction. This interaction was due to the combined effect of a trend of increased CA1 CBV (p = .06) and non-significantly decreased CA2/3 CBV (p = 0.14) in patients relative to healthy controls. These results support the emerging hypothesis of increased hippocampal activity as a biomarker of schizophrenia and highlight the importance of subfield-level investigations. PMID:25161901

Preservation of hippocampal neuron numbers and hippocampal subfield volumes in behaviorally characterized aged tree shrews.

PubMed

Keuker, Jeanine I H; de Biurrun, Gabriel; Luiten, Paul G M; Fuchs, Eberhard

2004-01-19

Aging is associated with a decreased ability to store and retrieve information. The hippocampal formation plays a critical role in such memory processes, and its integrity is affected during normal aging. We used tree shrews (Tupaia belangeri) as an animal model of aging, because in many characteristics, tree shrews are closer to primates than they are to rodents. Young and aged male tree shrews performed a holeboard spatial memory task, which permits assessment of reference and working memory. Upon completion of the behavioral measurements, we carried out modified stereological analyses of neuronal numbers in various subdivisions of the hippocampus and used the Cavalieri method to calculate the volumes of these subfields. Results showed that the working memory of aged tree shrews was significantly impaired compared with that of young animals, whereas the hippocampus-dependent reference memory remained unchanged by aging. Estimation of the number of neurons revealed preserved neuron numbers in the subiculum, in the subregions CA1, CA2, CA3, and in the hilus of the dentate gyrus. Volume measurements showed no aging-related changes in the volume of any of these hippocampal subregions, or in the molecular and granule cell layers of the dentate gyrus of tree shrews. We conclude that the observed changes in memory performance in aging tree shrews are not accompanied by observable reductions of hippocampal neuron numbers or hippocampal volume, rather, the changes in memory performance are more likely the result of modified subcellular mechanisms that are affected by the aging process. Copyright 2003 Wiley-Liss, Inc.

Science Books, A Quarterly Review, Volume 7 Number 4.

ERIC Educational Resources Information Center

American Association for the Advancement of Science, Washington, DC.

"Science Books" is published quarterly to review trade books, textbooks, and reference works in the pure and applied sciences for students in the elementary school, secondary school, and first two years of college. It includes selected advanced and professional books useful for reference by students and faculty members. The approximately 200…

Science Books, A Quarterly Review, Volume 7 Number 2.

ERIC Educational Resources Information Center

Science Books A Quarterly Review, 1971

1971-01-01

Science Books is published quarterly to review trade books, textbooks, and reference works in the pure and applied sciences for students in the elementary school, secondary school, and first two years of college. It includes selected advanced and professional books useful for reference by students and faculty members. The approximately 234 titles…

Science Books, Volume 10 Number 4.

ERIC Educational Resources Information Center

Wolff, Kathryn, Ed.

This quarterly journal reviews trade books, textbooks, and reference works in the pure and applied sciences for students in elementary and secondary schools and in the first two years of college. Included are selected advanced and professional books useful for reference by students and teachers. Each book is reviewed and annotated by a qualified…

Science Books, Vol. 10 No. 3.

ERIC Educational Resources Information Center

Wolff, Kathryn, Ed.

This quarterly journal reviews trade books, textbooks, and reference works in the pure and applied sciences for students in elementary and secondary schools and in the first two years of college. Included are selected advanced and professional books useful for reference to students and teachers. Each book is reviewed and annotated by a qualified…

Science Books, A Quarterly Review, Volume 7 Number 3.

ERIC Educational Resources Information Center

American Association for the Advancement of Science, Washington, DC.

"Science Books" is published quarterly to review trade books, textbooks, and reference works in the pure and applied sciences for students in the elementary school, secondary school, and first two years of college. It includes selected advanced and professional books useful for reference by students and faculty members. The approximately 240…

Science Books, A Quarterly Review, Volume 8 Number 1.

ERIC Educational Resources Information Center

American Association for the Advancement of Science, Washington, DC.

This quarterly journal reviews trade books, textbooks, and reference works in the pure and applied sciences for students in the elementary schools, in secondary school and in the first two years of college. Included are selected advanced and professional books useful for reference by students and faculty members. Annotations are listed in order of…

The Council of Europe's "Common European Framework of Reference for Languages" (CEFR): Approach, Status, Function and Use

ERIC Educational Resources Information Center

Martyniuk, Waldemar

2012-01-01

The Council of Europe's "Common European Framework of Reference for Languages" is rapidly becoming a powerful instrument for shaping language education policies in Europe and beyond. The task of relating language policies, language curricula, teacher education and training, textbook and course design and content, examinations and…

COURSE OUTLINE FOR FIRST SIX WEEKS FOR SCIENCE-LEVEL II, TALENT PRESERVATION CLASSES.

ERIC Educational Resources Information Center

Houston Independent School District, TX.

THE FIRST 6-WEEK UNIT CONCERNS ANIMAL LIFE, AND TOPICS INCLUDE PROTOZOA, INVERTEBRATES, AND VERTEBRATES. UNIT II, "THE HUMAN BODY", INCLUDES BODY SYSTEMS, HEALTH, AND SAFETY. TEXTBOOK REFERENCES, CONTENT OUTLINE, TEACHING SUGGESTIONS, REFERENCE READINGS, AND AUDIOVISUAL AIDS ARE GIVEN UNDER EACH TOPIC. IT IS SUGGESTED THAT FIRST…

A Review of Contraception and Abortion Content in Family Medicine Textbooks.

PubMed

Schubert, Finn D; Akse, Sarp; Bennett, Ariana H; Glassman, Nancy R; Gold, Marji

2015-01-01

Family physicians are critical providers of reproductive health care in the United States, and family physicians and trainees refer to textbooks as a source of clinical information. This study evaluates the coverage of reproductive health topics in current family medicine textbooks. We identified 12 common family medicine textbooks through a computerized literature search and through the recommendations of a local family medicine clerkship and evaluated 24 areas of reproductive health content (comprising contraceptive care, management of early pregnancy loss, and provision of induced abortion) for accuracy and thoroughness using criteria that we created based on the latest guidelines. All contraceptive methods evaluated were addressed in more than half of the textbooks, though discrepancies existed by method, with intrauterine devices (IUDs), external (male) condoms, and diaphragms addressed most frequently (10/12 texts) and male and female sterilization addressed least frequently (8/12 texts). While most contraceptive methods, when addressed, were usually addressed accurately, IUDs were often addressed inaccurately. Coverage of early pregnancy loss management was limited to 7/12 texts, and coverage of early abortion methods was even more limited, with only 4/12 texts addressing the topic. Family medicine textbooks do not uniformly provide correct and thorough information on reproductive health topics relevant to family medicine, and attention is needed to ensure that family physicians are receiving appropriate information and training to meet the reproductive health needs of US women.

MARC Coding of DDC for Subject Retrieval.

ERIC Educational Resources Information Center

Wajenberg, Arnold S.

1983-01-01

Recommends an expansion of MARC codes for decimal class numbers to enhance automated subject retrieval. Five values for a second indicator and two new subfields are suggested for encoding hierarchical relationships among decimal class numbers. Additional subfields are suggested to enhance retrieval through analysis of synthesized numbers in…

Marketing trends impede conceptual integration in psychology courses: Comment on Gurung et al. (2016).

PubMed

Carver, Charles S

2017-01-01

A recent American Psychologist article on teaching (Gurung et al., 2016) stressed the importance of fostering integration across topic areas. A current trend in publishing and marketing of textbooks is creating pressure that makes this goal harder to implement. The trend is offering custom tailoring of online texts by adopters, letting instructors assign some sections and make other sections unavailable to students. To permit this option, textbook publishers now insist that authors not cross-reference anywhere, so that no instructor will face the possibility of a student looking for material that has not been assigned and thus does not exist. Ironically, this pressure from publishers actively impedes conceptual integration in our textbooks. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Herpangina

MedlinePlus

... lead to this infection. Images Throat anatomy Mouth anatomy References Abzug MJ. Nonpolio enteroviruses. In: Kliegman RM, Stanton BF, St. Geme JW, Schor NF, eds. Nelson Textbook of Pediatrics . 20th ed. Philadelphia, PA: Elsevier; 2016: ...

BOOK REVIEW: String Theory in a Nutshell

NASA Astrophysics Data System (ADS)

Skenderis, Kostas

2007-11-01

The book 'String Theory in a Nutshell' by Elias Kiritsis provides a comprehensive introduction to modern string theory. String theory is the leading candidate for a theory that successfully unifies all fundamental forces of nature, including gravity. The subject has been continuously developing since the early 1970s, with classic textbooks on the subject being those of Green, Schwarz and Witten (1987) and Polchinski (1998). Since the latter was published there have been substantial developments, in particular in understanding black holes and gravity/gauge theory dualities. A textbook treatment of this important material is clearly needed, both by students and researchers in string theory and by mathematicians and physicists working in related fields. This book has a good selection of material, starting from basics and moving into classic and modern topics. In particular, Kiritsis' presentation of the basic material is complementary to that of the earlier textbooks and he includes a number of topics which are not easily found or covered adequately elsewhere, for example, loop corrections to string effective couplings. Overall the book nicely covers the major advances of the last ten years, including (non-perturbative) string dualities, black hole physics, AdS/CFT and matrix models. It provides a concise but fairly complete introduction to these subjects which can be used both by students and by researchers. Moreover the emphasis is on results that are reasonably established, as is appropriate for a textbook; concise summaries are given for subjects which are still in flux, with references to relevant reviews and papers. A positive feature of the book is that the bibliography sections at the end of each chapter provide a comprehensive guide to the literature. The bibliographies point to reviews and pedagogical papers on subjects covered in this book as well as those that were omitted. It is rare for a textbook to contain such a self-contained and detailed guide to the literature. In all, the book contains nearly five hundred exercises for the graduate-level student, which are useful both in teaching courses on string theory and for those who are studying by themselves. A nice feature of this book is that references are made to specific pages earlier in the book, rather than to chapters, which is helpful for students working through the book on their own. In summary,'String Theory in a Nutshell'is a valuable addition to the existing string theory textbooks; it is complementary to the previous books and gives a good treatment of subsequent developments. It is likely to become a staple reference on the subject, used both by students and researchers.

Affordable College Textbook Act

THOMAS, 113th Congress

Sen. Durbin, Richard J. [D-IL

2013-11-14

Senate - 11/14/2013 Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Open College Textbook Act of 2010

THOMAS, 111th Congress

Rep. Wu, David [D-OR-1

2010-02-02

House - 02/23/2010 Referred to the Subcommittee on Higher Education, Lifelong Learning, and Competitiveness. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Society Membership Profile: The Pattern of Subfield Associations.

ERIC Educational Resources Information Center

Czujko, Roman; And Others

An overview of the membership of nine societies that comprise the American Institute of Physics is presented, with attention to demographic characteristics, employers, work activity, salaries, physics subfields, and differences among the societies. Comparisons are made to surveys since 1979, and highlights on 1983 salaries are included. One…

Torsions within the Same Anxiety? Entification, Apophasis, History

ERIC Educational Resources Information Center

Baker, Bernadette

2008-01-01

In Anglophone educational research in the United States, the name Foucault has been more pointedly celebrated in some subfields such as curriculum studies relative to its more noticeable censorship in subfields such as history of education. This paper illustrates how such differential epistemological politics might be accounted for through…

Development of a histologically validated segmentation protocol for the hippocampal body.

PubMed

Steve, Trevor A; Yasuda, Clarissa L; Coras, Roland; Lail, Mohjevan; Blumcke, Ingmar; Livy, Daniel J; Malykhin, Nikolai; Gross, Donald W

2017-08-15

Recent findings have demonstrated that hippocampal subfields can be selectively affected in different disease states, which has led to efforts to segment the human hippocampus with in vivo magnetic resonance imaging (MRI). However, no studies have examined the histological accuracy of subfield segmentation protocols. The presence of MRI-visible anatomical landmarks with known correspondence to histology represents a fundamental prerequisite for in vivo hippocampal subfield segmentation. In the present study, we aimed to: 1) develop a novel method for hippocampal body segmentation, based on two MRI-visible anatomical landmarks (stratum lacunosum moleculare [SLM] & dentate gyrus [DG]), and assess its accuracy in comparison to the gold standard direct histological measurements; 2) quantify the accuracy of two published segmentation strategies in comparison to the histological gold standard; and 3) apply the novel method to ex vivo MRI and correlate the results with histology. Ultra-high resolution ex vivo MRI was performed on six whole cadaveric hippocampal specimens, which were then divided into 22 blocks and histologically processed. The hippocampal bodies were segmented into subfields based on histological criteria and subfield boundaries and areas were directly measured. A novel method was developed using mean percentage of the total SLM distance to define subfield boundaries. Boundary distances and subfield areas on histology were then determined using the novel method and compared to the gold standard histological measurements. The novel method was then used to determine ex vivo MRI measures of subfield boundaries and areas, which were compared to histological measurements. For direct histological measurements, the mean percentages of total SLM distance were: Subiculum/CA1 = 9.7%, CA1/CA2 = 78.4%, CA2/CA3 = 97.5%. When applied to histology, the novel method provided accurate measures for CA1/CA2 (ICC = 0.93) and CA2/CA3 (ICC = 0.97) boundaries, but not for the Subiculum/CA1 (ICC = -0.04) boundary. Accuracy was poorer using previous techniques for CA1/CA2 (maximum ICC = 0.85) and CA2/CA3 (maximum ICC = 0.88), with the previously reported techniques also performing poorly in defining the Subiculum/CA1 boundary (maximum ICC = 0.00). Ex vivo MRI measurements using the novel method were linearly related to direct measurements of SLM length (r 2 = 0.58), CA1/CA2 boundary (r 2 = 0.39) and CA2/CA3 boundary (r 2 = 0.47), but not for Subiculum/CA1 boundary (r 2 = 0.01). Subfield areas measured with the novel method on histology and ex vivo MRI were linearly related to gold standard histological measures for CA1, CA2, and CA3/CA4/DG. In this initial proof of concept study, we used ex vivo MRI and histology of cadaveric hippocampi to develop a novel segmentation protocol for the hippocampal body. The novel method utilized two anatomical landmarks, SLM & DG, and provided accurate measurements of CA1, CA2, and CA3/CA4/DG subfields in comparison to the gold standard histological measurements. The relationships demonstrated between histology and ex vivo MRI supports the potential feasibility of applying this method to in vivo MRI studies. Copyright © 2017. Published by Elsevier Inc.

[Classifications in forensic medicine and their logical basis].

PubMed

Kovalev, A V; Shmarov, L A; Ten'kov, A A

2014-01-01

The objective of the present study was to characterize the main requirements for the correct construction of classifications used in forensic medicine, with special reference to the errors that occur in the relevant text-books, guidelines, and manuals and the ways to avoid them. This publication continues the series of thematic articles of the authors devoted to the logical errors in the expert conclusions. The preparation of further publications is underway to report the results of the in-depth analysis of the logical errors encountered in expert conclusions, text-books, guidelines, and manuals.

Breathing difficulty - lying down

MedlinePlus

... orthopnea Images Breathing References Davis JL, Murray JF. History and physical examination. In: Broaddus VC, Mason RJ, Ernst JD, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine . 6th ed. Philadelphia, PA: Elsevier ...

Selected reference aids for small medical libraries.

PubMed

Duncan, H F

1970-04-01

This annotated list of 178 items is compiled as a guide to the development of the reference collection in a small medical library.Arrangement, following the pattern of the previous revision, is by broad subject groups. Titles are chiefly in English. Textbooks in subject fields have been omitted since these are covered adequately in several comprehensive guides to the literature.

The Pendulum as Presented in School Science Textbooks of Greece and Cyprus

ERIC Educational Resources Information Center

Koliopoulos, Dimitris; Constantinou, Costas

2005-01-01

When we refer to scientific knowledge, we, implicitly or explicitly, refer to its three components, namely its conceptual framework, its methodological principles and its cultural aspects. The pendulum is a topic of science teaching and learning where all three of these aspects can be examined with the aim of gaining a holistic appreciation of the…

Health psychology in Ghana: A review of the multidisciplinary origins of a young sub-field and its future prospects.

PubMed

de-Graft Aikins, Ama

2018-03-01

This article presents a historical overview of psychology applied to health and health psychology in Ghana. A brief history of health, illness and healthcare in Ghana is introduced. Then, the history of psychology in Ghana is presented, with signposts of the major turns in the field in relation to psychology and other disciplines applied to health and the emergence of health psychology as a sub-field. Selected health psychology studies are reviewed to highlight ideological trends in the field. Finally, future prospects are considered in terms of how the sub-field can transition into an established critical field with unique contributions to make to global health psychology.

Endometrial biopsy

MedlinePlus

... Names Biopsy - endometrium Images Pelvic laparoscopy Female reproductive anatomy Endometrial biopsy Uterus Endometrial biopsy References Beard JM, Osborn J. Common office procedures. In: Rakel RE, Rakel DP, eds. Textbook of Family Medicine . 9th ed. Philadelphia, PA: Elsevier ...

Enlarged adenoids

MedlinePlus

... Instructions Tonsil and adenoid removal - discharge Images Throat anatomy Adenoids References Wetmore RF. Tonsils and adenoids. In: Kliegman RM, Stanton BF, St. Geme JW, Schor NF, eds. Nelson Textbook of Pediatrics . 20th ed. Philadelphia, PA: Elsevier; 2016: ...

Eustachian tube patency

MedlinePlus

... to become blocked. Images Ear anatomy Eustachian tube anatomy References Kerschner JE, Preciado D. Otitis media. In: Kliegman RM, Stanton BF, St. Geme JW, Schor NF, eds. Nelson Textbook of Pediatrics . 20th ed. Philadelphia, PA: Elsevier; 2016: ...

Paraphimosis

MedlinePlus

... done correctly, prevents this condition. Images Male reproductive anatomy References Elder JS. Anomalies of the penis and urethra. In: Kliegman RM, Stanton BF, St. Geme JW, Schor NF, eds. Nelson Textbook of Pediatrics . 20th ed. Philadelphia, PA: Elsevier; 2016: ...

Penis

MedlinePlus

... Ambiguous genitalia Penile prosthesis Priapism Images Male reproductive anatomy References Elder JS. Anomalies of the penis and urethra. In: Kliegman RM, Stanton BF, St. Geme JW, Schor NF, eds. Nelson Textbook of Pediatrics. 20th ed. Philadelphia, PA: Elsevier; 2016: ...

Heterogeneous Catalysis.

ERIC Educational Resources Information Center

Vannice, M. A.

1979-01-01

Described is a graduate course in catalysis offered at Penn State University. A detailed course outline with 30 lecture topics is presented. A list of 42 references on catalysis used in place of a textbook is provided. (BT)

Pulse - bounding

MedlinePlus

... pulse References Fang JC, O'Gara PT. The history and physical examination. In: Mann DL, Zipes DP, Libby P, Bonow RO, Braunwald E, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine . 10th ed. Philadelphia, PA: Elsevier ...

Heart palpitations

MedlinePlus

... Yoga References Fang JC, O’Gara PT. The history and physical examination. In: Mann DL, Zipes DP, Libby P, Bonow RO, Braunwald E, eds. Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine . 10th ed. Philadelphia, PA: Elsevier ...

Open College Textbook Act of 2009

THOMAS, 111th Congress

Sen. Durbin, Richard J. [D-IL

2009-09-24

Senate - 09/24/2009 Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

A Columnar Primary Visual Cortex (V1) Model Emulation Using a PS3 Cell-Be Array

DTIC Science & Technology

2011-09-01

23 July 2010, pp 1-8, Barcelona , Spain, ISSN: 1098-7576, Print ISBN: 978-1-4244-6916, INSPEC Accession No.: 11593936, Digital Object Identifier...98subfields) X (128 FCs per subfield) X (64 minicolumns/ FC ) works out to 802816 minicolumns per hemisphere. All minicolumns within a

SoTL as a Subfield for Political Science Graduate Programs

ERIC Educational Resources Information Center

Trepanier, Lee

2017-01-01

This article offers a theoretical proposal of how political science graduate programs can emphasize teaching in the discipline by creating the subfield of the scholarship of teaching and learning (SoTL). Currently, these programs neither prepare their students for academic positions where teaching is valued nor participate in a disciplinary trend…

Brazilian Science between National and Foreign Journals: Methodology for Analyzing the Production and Impact in Emerging Scientific Communities.

PubMed

Strehl, Letícia; Calabró, Luciana; Souza, Diogo Onofre; Amaral, Lívio

2016-01-01

In recent decades, we have observed an intensification of science, technology and innovation activities in Brazil. The increase in production of scientific papers indexed in international databases, however, has not been accompanied by an equivalent increase in the impact of publications. This paper presents a methodology for analyzing production and the impact of certain research areas in Brazil related to two aspects: the origin of the journals (national or foreign) and international collaboration. These two variables were selected for being of particular importance in understanding the context of scientific production and communication in countries with emerging economies. The sample consisted of papers written by Brazilian researchers in 19 subfields of knowledge published from 2002 to 2011, totaling 85,082 papers. To calculate the impact, we adopted a normalized indicator called the relative subfield citedness (Rw) using a window of 5 years to obtain measurements evaluated in 2 different years: 2007 and 2012. The data on papers and citations were collected from the Web of Science database. From the results, we note that most of the subfields have presented, from one quinquennium to another, improved performance in the world production rankings. Regarding publication in national and foreign journals, we observed a trend in the distribution maintenance of production of the subfields based on the origin of the journal. Specifically, for impact, we identified a lower Rw pattern for Brazilian papers when they were published in national journals in all subfields. When Brazilian products are published in foreign journals, we observed a higher impact for those papers, even surpassing the average global impact in some subfields. For international collaboration, we analyzed the percentage of participation of foreign researchers and the connection between collaboration and the impact of papers, especially emphasizing the distinction of hyperauthorship papers in terms of production and impact.

Roles of hippocampal subfields in verbal and visual episodic memory.

PubMed

Zammit, Andrea R; Ezzati, Ali; Zimmerman, Molly E; Lipton, Richard B; Lipton, Michael L; Katz, Mindy J

2017-01-15

Selective hippocampal (HC) subfield atrophy has been reported in older adults with mild cognitive impairment and Alzheimer's disease. The goal of this study was to investigate the associations between the volume of hippocampal subfields and visual and verbal episodic memory in cognitively normal older adults. This study was conducted on a subset of 133 participants from the Einstein Aging Study (EAS), a community-based study of non-demented older adults systematically recruited from the Bronx, N.Y. All participants completed comprehensive EAS neuropsychological assessment. Visual episodic memory was assessed using the Complex Figure Delayed Recall subtest from the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). Verbal episodic memory was assessed using Delayed Recall from the Free and Cued Selective Reminding Test (FCSRT). All participants underwent 3T MRI brain scanning with subsequent automatic measurement of the hemispheric hippocampal subfield volumes (CA1, CA2-CA3, CA4-dente gyrus, presubiculum, and subiculum). We used linear regressions to model the association between hippocampal subfield volumes and visual and verbal episodic memory tests while adjusting for age, sex, education, and total intracranial volume. Participants had a mean age of 78.9 (SD=5.1) and 60.2% were female. Total hippocampal volume was associated with Complex Figure Delayed Recall (β=0.31, p=0.001) and FCSRT Delayed Recall (β=0.27, p=0.007); subiculum volume was associated with Complex Figure Delayed Recall (β=0.27, p=0.002) and FCSRT Delayed Recall (β=0.24, p=0.010); CA1 was associated with Complex Figure Delayed Recall (β=0.26, p<0.002) and FCSRT Delayed Recall (β=0.20, p=0.025). Our findings confirm previous research on the specific roles of CA1 and subiculum in episodic memory. Our results suggest that hippocampal subfields have sensitive roles in the process of visual and verbal episodic memory. Copyright © 2016 Elsevier B.V. All rights reserved.

Hippocampal lipid differences in Alzheimer's disease: a human brain study using matrix-assisted laser desorption/ionization-imaging mass spectrometry.

PubMed

Mendis, Lakshini H S; Grey, Angus C; Faull, Richard L M; Curtis, Maurice A

2016-10-01

Alzheimer's disease (AD), the leading cause of dementia, is pathologically characterized by β-amyloid plaques and tau tangles. However, there is also evidence of lipid dyshomeostasis-mediated AD pathology. Given the structural diversity of lipids, mass spectrometry is a useful tool for studying lipid changes in AD. Although there have been a few studies investigating lipid changes in the human hippocampus in particular, there are few reports on how lipids change in each hippocampal subfield (e.g., Cornu Ammonis [CA] 1-4, dentate gyrus [DG] etc.). Since each subfield has its own function, we postulated that there could be lipid changes that are unique to each. We used matrix-assisted laser desorption/ionization-imaging mass spectrometry to investigate specific lipid changes in each subfield in AD. Data from the hippocampus region of six age- and gender-matched normal and AD pairs were analyzed with SCiLS lab 2015b software (SCiLS GmbH, Germany; RRID:SCR_014426), using an analysis workflow developed in-house. Hematoxylin, eosin, and luxol fast blue staining were used to precisely delineate each anatomical hippocampal subfield. Putative lipid identities, which were consistent with published data, were assigned using MS/MS. Both positively and negatively charged lipid ion species were abundantly detected in normal and AD tissue. While the distribution pattern of lipids did not change in AD, the abundance of some lipids changed, consistent with trends that have been previously reported. However, our results indicated that the majority of these lipid changes specifically occur in the CA1 region. Additionally, there were many lipid changes that were specific to the DG. Matrix-assisted laser desorption/ionization-imaging mass spectrometry and our analysis workflow provide a novel method to investigate specific lipid changes in hippocampal subfields. Future work will focus on elucidating the role that specific lipid differences in each subfield play in AD pathogenesis.

Brazilian Science between National and Foreign Journals: Methodology for Analyzing the Production and Impact in Emerging Scientific Communities

PubMed Central

Calabró, Luciana; Souza, Diogo Onofre; Amaral, Lívio

2016-01-01

In recent decades, we have observed an intensification of science, technology and innovation activities in Brazil. The increase in production of scientific papers indexed in international databases, however, has not been accompanied by an equivalent increase in the impact of publications. This paper presents a methodology for analyzing production and the impact of certain research areas in Brazil related to two aspects: the origin of the journals (national or foreign) and international collaboration. These two variables were selected for being of particular importance in understanding the context of scientific production and communication in countries with emerging economies. The sample consisted of papers written by Brazilian researchers in 19 subfields of knowledge published from 2002 to 2011, totaling 85,082 papers. To calculate the impact, we adopted a normalized indicator called the relative subfield citedness (Rw) using a window of 5 years to obtain measurements evaluated in 2 different years: 2007 and 2012. The data on papers and citations were collected from the Web of Science database. From the results, we note that most of the subfields have presented, from one quinquennium to another, improved performance in the world production rankings. Regarding publication in national and foreign journals, we observed a trend in the distribution maintenance of production of the subfields based on the origin of the journal. Specifically, for impact, we identified a lower Rw pattern for Brazilian papers when they were published in national journals in all subfields. When Brazilian products are published in foreign journals, we observed a higher impact for those papers, even surpassing the average global impact in some subfields. For international collaboration, we analyzed the percentage of participation of foreign researchers and the connection between collaboration and the impact of papers, especially emphasizing the distinction of hyperauthorship papers in terms of production and impact. PMID:27171223

Hippocampal subfield volumetry in mild cognitive impairment, Alzheimer's disease and semantic dementia.

PubMed

La Joie, Renaud; Perrotin, Audrey; de La Sayette, Vincent; Egret, Stéphanie; Doeuvre, Loïc; Belliard, Serge; Eustache, Francis; Desgranges, Béatrice; Chételat, Gaël

2013-01-01

Hippocampal atrophy is a well-known feature of Alzheimer's disease (AD), but sensitivity and specificity of hippocampal volumetry are limited. Neuropathological studies have shown that hippocampal subfields are differentially vulnerable to AD; hippocampal subfield volumetry may thus prove to be more accurate than global hippocampal volumetry to detect AD. CA1, subiculum and other subfields were manually delineated from 40 healthy controls, 18 AD, 17 amnestic Mild Cognitive Impairment (aMCI), and 8 semantic dementia (SD) patients using a previously developed high resolution MRI procedure. Non-parametric group comparisons and receiver operating characteristic (ROC) analyses were conducted. Complementary analyses were conducted to evaluate differences of hemispheric asymmetry and anterior-predominance between AD and SD patients and to distinguish aMCI patients with or without β-amyloid deposition as assessed by Florbetapir-TEP. Global hippocampi were atrophied in all three patient groups and volume decreases were maximal in the CA1 subfield (22% loss in aMCI, 27% in both AD and SD; all p < 0.001). In aMCI, CA1 volumetry was more accurate than global hippocampal measurement to distinguish patients from controls (areas under the ROC curve = 0.88 and 0.76, respectively; p = 0.05) and preliminary analyses suggest that it was independent from the presence of β-amyloid deposition. In patients with SD, whereas the degree of CA1 and subiculum atrophy was similar to that found in AD patients, hemispheric and anterior-posterior asymmetry were significantly more marked than in AD with greater involvement of the left and anterior hippocampal subfields. The findings suggest that CA1 measurement is more sensitive than global hippocampal volumetry to detect structural changes at the pre-dementia stage, although the predominance of CA1 atrophy does not appear to be specific to AD pathophysiological processes.

A harmonized segmentation protocol for hippocampal and parahippocampal subregions: why do we need one and what are the key goals?

PubMed Central

Olsen, Rosanna K.; Berron, David; Carr, Valerie A.; Stark, Craig E.L.; Amaral, Robert S.C.; Amunts, Katrin; Augustinack, Jean C.; Bender, Andrew R.; Bernstein, Jeffrey D.; Boccardi, Marina; Bocchetta, Martina; Burggren, Alison; Chakravarty, M. Mallar; Chupin, Marie; Ekstrom, Arne; de Flores, Robin; Insausti, Ricardo; Kanel, Prabesh; Kedo, Olga; Kennedy, Kristen M.; Kerchner, Geoffrey A.; LaRocque, Karen F.; Liu, Xiuwen; Maass, Anne; Malykhin, Nicolai; Mueller, Susanne G.; Ofen, Noa; Palombo, Daniela J.; Parekh, Mansi B.; Pluta, John B.; Pruessner, Jens C.; Raz, Naftali; Rodrigue, Karen M.; Schoemaker, Dorothee; Shafer, Andrea T.; Steve, Trevor A.; Suthana, Nanthia; Wang, Lei; Winterburn, Julie L.; Yassa, Michael A.; Yushkevich, Paul A.; la Joie, Renaud

2016-01-01

The advent of high-resolution magnetic resonance imaging (MRI) has enabled in vivo research in a variety of populations and diseases on the structure and function of hippocampal subfields and subdivisions of the parahippocampal gyrus. Due to the many extant and highly discrepant segmentation protocols, comparing results across studies is difficult. To overcome this barrier, the Hippocampal Subfields Group was formed as an international collaboration with the aim of developing a harmonized protocol for manual segmentation of hippocampal and parahippocampal subregions on high-resolution MRI. In this commentary we discuss the goals for this protocol and the associated key challenges involved in its development. These include differences among existing anatomical reference materials, striking the right balance between reliability of measurements and anatomical validity, and the development of a versatile protocol that can be adopted for the study of populations varying in age and health. The commentary outlines these key challenges, as well as the proposed solution of each, with concrete examples from our working plan. Finally, with two examples, we illustrate how the harmonized protocol, once completed, is expected to impact the field by producing measurements that are quantitatively comparable across labs and by facilitating the synthesis of findings across different studies. PMID:27862600

Advances in Patient Classification for Traditional Chinese Medicine: A Machine Learning Perspective

PubMed Central

Zhao, Changbo; Li, Guo-Zheng; Wang, Chengjun; Niu, Jinling

2015-01-01

As a complementary and alternative medicine in medical field, traditional Chinese medicine (TCM) has drawn great attention in the domestic field and overseas. In practice, TCM provides a quite distinct methodology to patient diagnosis and treatment compared to western medicine (WM). Syndrome (ZHENG or pattern) is differentiated by a set of symptoms and signs examined from an individual by four main diagnostic methods: inspection, auscultation and olfaction, interrogation, and palpation which reflects the pathological and physiological changes of disease occurrence and development. Patient classification is to divide patients into several classes based on different criteria. In this paper, from the machine learning perspective, a survey on patient classification issue will be summarized on three major aspects of TCM: sign classification, syndrome differentiation, and disease classification. With the consideration of different diagnostic data analyzed by different computational methods, we present the overview for four subfields of TCM diagnosis, respectively. For each subfield, we design a rectangular reference list with applications in the horizontal direction and machine learning algorithms in the longitudinal direction. According to the current development of objective TCM diagnosis for patient classification, a discussion of the research issues around machine learning techniques with applications to TCM diagnosis is given to facilitate the further research for TCM patient classification. PMID:26246834

Scrotal swelling

MedlinePlus

... of the scrotum; Testicular enlargement Images Male reproductive anatomy References Elder JS. Disorders and anomalies of the scrotal contents. In: Kliegman RM, Stanton BF, St. Geme JW, Schor NF, eds. Nelson Textbook of Pediatrics . 20th ed. Philadelphia, PA: Elsevier; 2016: ...

Gallbladder removal - laparoscopic

MedlinePlus

... you have nausea and vomiting Images Gallbladder Gallbladder anatomy Laparoscopic surgery - series References Jackson PG, Evans SRT. Biliary system. In: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery: The Biological Basis of Modern Surgical ...

Nipple problems

MedlinePlus

... Abnormal discharge from the nipple Normal female breast anatomy References Hunt KK, Mittendorf EA. Diseases of the breast. In: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery . 20th ed. Philadelphia, PA: Elsevier; 2017: ...

Chromatography: Are We Getting It Right?

ERIC Educational Resources Information Center

Maitland, Pamela D.; Maitland, David P.

2002-01-01

Explains the basics of chromatography which is used to demonstrate the separation of plant photosynthetic pigments. Reports the results of an evaluative study that explored textbook errors in explaining how chromatography works. (Contains 13 references.) (Author/YDS)

Astronautic structures manual

NASA Technical Reports Server (NTRS)

1977-01-01

Three-volume reference work serves as catalog of analysis techniques for elastic and inelastic stress ranges and as source on background and development of methods. Information is condensation of published journal articles, industry and university publications, textbooks, and government documents.

Textbooks, Teachers and Full-Colour Vision: Some Thoughts on Evaluating Environmental Education "Performance".

ERIC Educational Resources Information Center

Courtenay-Hall, Pamela

1998-01-01

Discusses the problem of environmental bias and critiques Michael Sanera's approach to evaluation of environmental education performance. Notes that problems result from bias in curriculum materials. Contains 20 references. (DDR)

Nature of Environmental Education in Bangladesh: A School Level Assessment with Reference to the National Curriculum

ERIC Educational Resources Information Center

Chowdhury, M. A. Taiyeb

2014-01-01

This paper attempts to identify the nature of formal environmental education in Bangladesh at school level with particular reference to the national curriculum. The main objective of the study is to assess the contents of the school textbooks for each standard, and to see whether the diversified themes covered are a good representation of…

Physics Education Research: A Research Subfield of Physics with Gender Parity

ERIC Educational Resources Information Center

Barthelemy, Ramón S.; Van Dusen, Ramón S.; Henderson, Charles

2015-01-01

Women currently outnumber men in obtaining undergraduate degrees but are underrepresented within STEM fields. However, women's representation varies by STEM field, and even further by STEM subfield. One field that has held a persistent low representation of women is physics. This paper seeks to uncover the truth behind an anecdotal claim that the…

Gendered Authorship and Demographic Research: An Analysis of 50 Years of Demography.

PubMed

Krapf, Sandra; Kreyenfeld, Michaela; Wolf, Katharina

2016-08-01

Demography, the official journal of the Population Association of America, has been given the highest rating among demographic journals by the Social Sciences Citation Index (SSCI). Our aim here is to investigate the development of research subfields and female authorship in Demography over the last 50 years. We find that female authorship in Demography has risen considerably since the 1980s and that currently a woman is about as likely as a man to be the sole or the first author of a paper published in the journal. However, we find some differences by subfield. Women seem to be overrepresented in the "family and household" research subfield but underrepresented in the "mortality and health" and "data and methods" categories.

Gravitational Waves: Experiments

NASA Astrophysics Data System (ADS)

Cerdonio, M.

2003-01-01

These notes are intended to bring to non-specialists the message about the status of the experimental searches, both in achievements and in near and far future prospective. I try to describe the whole matter in simple words, without the use of the formalism, and rather indicate to the interested reader a selection among an enormous literature. For the actual shaping up of current research efforts, I make specific reference to most recent papers. For much nicer pictures and graphs than I could possibly squeeze in here, I heavily refere to the web sites of the experiments, which are kept updated with a resolution of weeks and are thus, in these times, the most complete and updated source of information. Because of my own involvement with "bar" detectors I will, with apologies, dedicate more attention to the subfield of so called acoustic detectors.

Testicular biopsy

MedlinePlus

... Names Biopsy - testicle Images Endocrine glands Male reproductive anatomy Testicular biopsy References Garibaldi LR, Chematilly W. Disorders of pubertal development. In: Kliegman RM, Stanton BF, St. Geme JW, Schor NF, eds. Nelson Textbook of Pediatrics . 20th ed. Philadelphia, PA: Elsevier; 2016: ...

Oropharynx lesion biopsy

MedlinePlus

... Mouth lesion biopsy; Oral cancer - biopsy Images Throat anatomy Oropharyngeal biopsy References Lee FE-H, Treanor JJ. Viral infections. In: Broaddus VC, Mason RJ, Ernst JD, et al, eds. Murray & Nadel's Textbook of Respiratory Medicine . 6th ed. Philadelphia, PA: Elsevier ...

Research on Pictures in Instructional Texts: The Need for a Broadened Perspective.

ERIC Educational Resources Information Center

Brody, Philip J.

1981-01-01

Reviews research examining the effects of pictorial illustrations on learning from textbooks; notes differences in purpose, approach, and methodology; identifies some shortcomings; and offers suggestions for future research. Forty references are listed. (FM)

What Chemistry To Teach Engineers?

ERIC Educational Resources Information Center

Hawkes, Stephen J.

2000-01-01

Examines possible general chemistry topics that would be most relevant and practical for engineering majors. Consults the Accreditation Board for Engineering and Technology (ABET), engineering textbooks, texts from other required subjects, and practicing engineers for recommendations. (Contains 24 references.) (WRM)

Curricular Controversy in the Math Wars: A Battle Without Winners.

ERIC Educational Resources Information Center

Reys, Robert E.

2001-01-01

Discusses the state of the mathematics textbook market and the debate surrounding the efforts to improve mathematics instruction, including the standards-based mathematics curriculum supported by the National Science Foundation. (Contains 12 references.) (PKP)

Learning Opportunities With Creation of Open Source Textbooks (LOW COST) Act of 2009

THOMAS, 111th Congress

Rep. Foster, Bill [D-IL-14

2009-03-12

House - 05/14/2009 Referred to the Subcommittee on Higher Education, Lifelong Learning, and Competitiveness. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Hippocampal subfield volumes in short- and long-term lithium-treated patients with bipolar I disorder.

PubMed

Simonetti, Alessio; Sani, Gabriele; Dacquino, Claudia; Piras, Fabrizio; De Rossi, Pietro; Caltagirone, Carlo; Coryell, William; Spalletta, Gianfranco

2016-06-01

Patients diagnosed with bipolar disorder (BP) may experience hippocampal atrophy. Lithium exposure has been associated with increased hippocampal volumes. However, its effects on hippocampal subfields remain to be clarified. We investigated the effects of short- and long-term lithium exposure on the hippocampus and its subfields in patients affected by bipolar I disorder (BP-I). Hippocampal subfields and total hippocampal volumes were measured in 60 subjects divided into four groups: 15 patients with BP-I who were never exposed to lithium [no-exposure group (NE)], 15 patients with BP-I exposed to lithium for < 24 months [short-exposure group (SE)], 15 patients with BP-I exposed to lithium for > 24 months [long-exposure group (LE)], and 15 healthy control subjects (HC). The SE and NE groups showed smaller total hippocampal volumes and smaller bilateral cornu ammonis CA2-3, CA4-dentate gyrus (DG), presubiculum, and subiculum volumes compared with HC. The LE group showed larger total hippocampal volumes and bilateral CA2-3, left CA4-DG, left presubiculum, and right subiculum volumes compared with the NE group, and larger volumes of the right CA2-3, left CA4-DG, left presubiculum, and right subiculum compared with the SE group. No differences were found between the LE group and HC or between the SE and NE groups. Long-term, but not short-term, exposure to lithium treatment may exert neuroprotective effects on specific hippocampal subfields linked to disease progression. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Focal CA3 hippocampal subfield atrophy following LGI1 VGKC-complex antibody limbic encephalitis

PubMed Central

Miller, Thomas D.; Chong, Trevor T.-J.; Aimola Davies, Anne M.; Ng, Tammy W.C.; Johnson, Michael R.; Irani, Sarosh R.; Vincent, Angela; Husain, Masud; Jacob, Saiju; Maddison, Paul; Kennard, Christopher; Gowland, Penny A.

2017-01-01

Magnetic resonance imaging has linked chronic voltage-gated potassium channel (VGKC) complex antibody-mediated limbic encephalitis with generalized hippocampal atrophy. However, autoantibodies bind to specific rodent hippocampal subfields. Here, human hippocampal subfield (subiculum, cornu ammonis 1-3, and dentate gyrus) targets of immunomodulation-treated LGI1 VGKC-complex antibody-mediated limbic encephalitis were investigated using in vivo ultra-high resolution (0.39 × 0.39 × 1.0 mm3) 7.0 T magnetic resonance imaging [n = 18 patients, 17 patients (94%) positive for LGI1 antibody and one patient negative for LGI1/CASPR2 but positive for VGKC-complex antibodies, mean age: 64.0 ± 2.55 years, median 4 years post-limbic encephalitis onset; n = 18 controls]. First, hippocampal subfield quantitative morphometry indicated significant volume loss confined to bilateral CA3 [F(1,34) = 16.87, P < 0.0001], despite hyperintense signal evident in 5 of 18 patients on presentation. Second, early and later intervention (<3 versus >3 months from symptom onset) were associated with CA3 atrophy. Third, whole-brain voxel-by-voxel morphometry revealed no significant grey matter loss. Fourth, CA3 subfield atrophy was associated with severe episodic but not semantic amnesia for postmorbid autobiographical events that was predicted by variability in CA3 volume. The results raise important questions about the links with histopathology, the impact of the observed focal atrophy on other CA3-mediated reconstructive and episodic mechanisms, and the role of potential antibody-mediated pathogenicity as part of the pathophysiology cascade in humans. PMID:28369215

Citation Patterns of Engineering, Statistics, and Computer Science Researchers: An Internal and External Citation Analysis across Multiple Engineering Subfields

ERIC Educational Resources Information Center

Kelly, Madeline

2015-01-01

This study takes a multidimensional approach to citation analysis, examining citations in multiple subfields of engineering, from both scholarly journals and doctoral dissertations. The three major goals of the study are to determine whether there are differences between citations drawn from dissertations and those drawn from journal articles; to…

From Education for Peace to Education in Conflict: Changes in UNESCO Discourse, 1945-2015

ERIC Educational Resources Information Center

Lerch, Julia C.; Buckner, Elizabeth

2018-01-01

Since the turn of the twenty-first century, the global education community has focused significant attention on the promotion of education in fragile and conflict-affected contexts, embodied in the growth of a new sub-field called Education in Emergencies. This article points out the surprising distinction of this new sub-field from the more…

Automated measurement of hippocampal subfields in PTSD: Evidence for smaller dentate gyrus volume.

PubMed

Hayes, Jasmeet P; Hayes, Scott; Miller, Danielle R; Lafleche, Ginette; Logue, Mark W; Verfaellie, Mieke

2017-12-01

Smaller hippocampal volume has been consistently observed as a biomarker of posttraumatic stress disorder (PTSD). However, less is known about individual volumes of the subfields composing the hippocampus such as the dentate gyrus and cornu ammonis (CA) fields 1-4 in PTSD. The aim of the present study was to examine the hypothesis that volume of the dentate gyrus, a region putatively involved in distinctive encoding of similar events, is smaller in individuals with PTSD versus trauma-exposed controls. Ninety-seven recent war veterans underwent structural imaging on a 3T scanner and were assessed for PTSD using the Clinician-Administered PTSD Scale. The hippocampal subfield automated segmentation program available through FreeSurfer was used to segment the CA4/dentate gyrus, CA1, CA2/3, presubiculum, and subiculum of the hippocampus. Results showed that CA4/dentate gyrus subfield volume was significantly smaller in veterans with PTSD and scaled inversely with PTSD symptom severity. These results support the view that dentate gyrus abnormalities are associated with symptoms of PTSD, although additional evidence is necessary to determine whether these abnormalities underlie fear generalization and other memory alterations in PTSD. Published by Elsevier Ltd.

A pedagogical analysis of science textbooks: How can we proceed?

NASA Astrophysics Data System (ADS)

Koulaidis, Vasilis; Tsatsaroni, Anna

1996-03-01

This paper discusses some of the available frameworks for the pedagogical analysis of school science textbooks. First, it distinguishes between (a) studies which focus on elements of textbooks, such as the content, vocabulary, illustrations used, and the teaching methods promoted; and (b) those which consider the principles that organize the content and the form of presentation. In attempting to consider the sorts of principles that may be used in the studies categorised under (b), two crucial issues are discussed. The first issue refers to the relationship between scientific knowledge and school knowledge, which, as the relevant literature suggests, might not be conceived merely as a simplified “casting” of the scientific structure, but rather should be understood as a complex social process. The second issue explicitly addresses the nature of the pedagogic relationship and the place of the pedagogic text within it. Recent views about the nature of knowledge, it is argued, would suggest a reconceptualisation of the teaching activity, and indicate a model according to which the three elements of the teaching situation-the content, the pupil and the teacher—are seen as being (re)constituted in their articulation within and through the text(book). Thus, for example, what is to be a competent pupil in this approach is a function of the text. On the basis of these considerations, three approaches to the analysis of science textbooks are discussed: the socio-cognitive, the sociolinguistic and the socio-epistemic. The relative merits of the third approach are considered, and some examples are used from Greek science textbooks.

Curvature of the penis

MedlinePlus

... penis. Alternative Names Peyronie disease Images Male reproductive anatomy Male reproductive system References Elder JS. Anomalies of the penis and urethra. In: Kliegman RM, Stanton BF, St. Geme JW, Schor NF, eds. Nelson Textbook of Pediatrics . 20th ed. Philadelphia, PA: Elsevier; 2016: ...

Thoracic CT

MedlinePlus

... CT scan Vertebra, thoracic (mid back) Normal lung anatomy Thoracic organs References Gotway MB, Panse PM, Gruden JF, Elicker BM. Thoracic radiology. In: Broaddus VC, Mason RJ, Ernst JD, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine . 6th ed. Philadelphia, PA: Elsevier ...

Pulmonary veno-occlusive disease

MedlinePlus

... disorder. Alternative Names Pulmonary vaso-occlusive disease Images Respiratory system References Chin K, Channick RN. Pulmonary hypertension. In: Broaddus VC, Mason RJ, Ernst JD, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine . 6th ed. Philadelphia, PA: Elsevier Saunders; 2016: ...

Haeckel's Embryos and Evolution: Setting the Record Straight.

ERIC Educational Resources Information Center

Wells, Jonathan

1999-01-01

Argues that Ernst Haeckel's drawings of vertebrate embryos (1891), which have been widely used in biology textbooks to illustrate his "Biogenetic Law", are factually flawed. Discusses the problems with Haeckel's drawings and his theory. Contains 14 references. (WRM)

Nuclear Reactor Physics

NASA Astrophysics Data System (ADS)

Stacey, Weston M.

2001-02-01

An authoritative textbook and up-to-date professional's guide to basic and advanced principles and practices Nuclear reactors now account for a significant portion of the electrical power generated worldwide. At the same time, the past few decades have seen an ever-increasing number of industrial, medical, military, and research applications for nuclear reactors. Nuclear reactor physics is the core discipline of nuclear engineering, and as the first comprehensive textbook and reference on basic and advanced nuclear reactor physics to appear in a quarter century, this book fills a large gap in the professional literature. Nuclear Reactor Physics is a textbook for students new to the subject, for others who need a basic understanding of how nuclear reactors work, as well as for those who are, or wish to become, specialists in nuclear reactor physics and reactor physics computations. It is also a valuable resource for engineers responsible for the operation of nuclear reactors. Dr. Weston Stacey begins with clear presentations of the basic physical principles, nuclear data, and computational methodology needed to understand both the static and dynamic behaviors of nuclear reactors. This is followed by in-depth discussions of advanced concepts, including extensive treatment of neutron transport computational methods. As an aid to comprehension and quick mastery of computational skills, he provides numerous examples illustrating step-by-step procedures for performing the calculations described and chapter-end problems. Nuclear Reactor Physics is a useful textbook and working reference. It is an excellent self-teaching guide for research scientists, engineers, and technicians involved in industrial, research, and military applications of nuclear reactors, as well as government regulators who wish to increase their understanding of nuclear reactors.

Stepping Backwards in Development: Integrating Developmental Speech Perception with Lexical and Phonological Development--A Commentary on Stoel-Gammon's "Relationships between Lexical and Phonological Development in Young Children"

ERIC Educational Resources Information Center

Zamuner, Tania S.

2011-01-01

Within the subfields of linguistics, traditional approaches tend to examine different phenomena in isolation. As Stoel-Gammon (this issue) correctly states, there is little interaction between the subfields. However, for a more comprehensive understanding of language acquisition in general and, more specifically, lexical and phonological…

Differential influence of hippocampal subfields to memory formation: insights from patients with temporal lobe epilepsy.

PubMed

Coras, Roland; Pauli, Elisabeth; Li, Jinmei; Schwarz, Michael; Rössler, Karl; Buchfelder, Michael; Hamer, Hajo; Stefan, Hermann; Blumcke, Ingmar

2014-07-01

To clarify the anatomical organization of human memory remains a major challenge in clinical neuroscience. Experimental data suggest dentate gyrus granule cells play a major role in memory acquisition, i.e. pattern separation and rapid pattern completion, whereas hippocampal CA1 neurons are implicated in place memory and autobiographical memory retrieval. Patients with temporal lobe epilepsy present with a broad spectrum of memory impairment, which can be assessed during clinical examination. Although long seizure histories may contribute to a pathophysiological reorganization of functional connectivity, surgical resection of the epileptic hippocampus offers a unique possibility to anatomically study the differential contribution of hippocampal subfields to compromised learning and memory in humans. Herein, we tested the hypothesis of hippocampal subfield specialization in a series of 100 consecutive patients with temporal lobe epilepsy submitted to epilepsy surgery. Memory profiles were obtained from intracarotid amobarbital testing and non-invasive verbal memory assessment before surgery, and correlated with histopathologically quantified cell loss pattern in hippocampal subfields obtained from the same patients using the new international consensus classification for hippocampal sclerosis proposed by the International League against Epilepsy (HS ILAE). Interestingly, patients with CA1 predominant cell loss (HS ILAE Type 2; n = 13) did not show declarative memory impairment and were indistinguishable from patients without any hippocampal cell loss (n = 19). In contrast, 63 patients with neuronal loss affecting all hippocampal subfields including CA1, CA4 and dentate gyrus (HS ILAE Type 1), or predominant cell loss in CA4 and partially affecting also CA3 and dentate gyrus (HS ILAE Type 3, n = 5) showed significantly reduced declarative memory capacities (intracarotid amobarbital testing: P < 0.001; verbal memory: P < 0.05). Our results suggested an alternative model of how memory processing can be organized amongst hippocampal subfields, and that CA1 pyramidal cells are less critically involved in declarative human memory acquisition compared to dentate gyrus granule cells or CA4/CA3 pyramidal cells. © The Author (2014). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Roles of PTEN-induced putative kinase 1 and dynamin-related protein 1 in transient global ischemia-induced hippocampal neuronal injury

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Shang-Der, E-mail: chensd@adm.cgmh.org.tw; Center for Translational Research in Biomedical Sciences, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taiwan; Lin, Tsu-Kung

Recent studies showed that increased mitochondrial fission is an early event of cell death during cerebral ischemia and dynamin-related protein 1 (Drp1) plays an important role in mitochondrial fission, which may be regulated by PTEN-induced putative kinase 1 (PINK1), a mitochondrial serine/threonine-protein kinase thought to protect cells from stress-induced mitochondrial dysfunction and regulate mitochondrial fission. However, the roles of PINK1 and Drp1 in hippocampal injury caused by transient global ischemia (TGI) remain unknown. We therefore tested the hypothesis that TGI may induce PINK1 causing downregulation of Drp1 phosphorylation to enhance hippocampal neuronal survival, thus functioning as an endogenous neuroprotective mechanism.more » We found progressively increased PINK1 expression in the hippocampal CA1 subfield1-48 h following TGI, reaching the maximal level at 4 h. Despite lack of changes in the expression level of total Drp1 and phosphor-Drp1 at Ser637, TGI induced a time-dependent increase of Drp1 phosphorlation at Ser616 that peaked after 24 h. Notably, PINK1-siRNA increased p-Drp1(Ser616) protein level in hippocampal CA1 subfield 24 h after TGI. The PINK1 siRNA also aggravated the TGI-induced oxidative DNA damage with an increased 8-hydroxy-deoxyguanosine (8-OHdG) content in hippocampal CA1 subfield. Furthermore, PINK1 siRNA also augmented TGI-induced apoptosis as evidenced by the increased numbers of TUNEL-positive staining and enhanced DNA fragmentation. These findings indicated that PINK1 is an endogenous protective mediator vital for neuronal survival under ischemic insult through regulating Drp1 phosphorylation at Ser616. - Highlights: • Transient global ischemia increases expression of PINK1 and p-Drp1 at Ser616 in hippocampal CA1 subfield. • PINK1-siRNA decreases PINK1 expression but increases p-Drp1 at Ser616 in hippocampal CA1 subfield. • PINK1-siRNA augments oxidative stress and neuronal damage in hippocampal CA1 subfield.« less

[An approach regarding the use of medication in biology textbooks as a strategy for health promotion].

PubMed

Corrêa, Anderson Domingues; Caminha, Juliana dos Reis; de Souza, Cristina Alves Magalhães; Alves, Luiz Anastacio

2013-10-01

The inappropriate use of medication represents a major threat to public health and drugs rank first among the agents causing intoxication in Brazil, ahead of poisons for rodents and insects, illegal drugs, pesticides, cleaning products and spoiled food. The National Curriculum of Secondary Education Parameters (PCN+) give major emphasis to health, since the reference to Drugs is mentioned repeatedly in the text. The scope of this research was to study the approaches to drug use in textbooks. For this purpose, eleven biology textbooks were analyzed, namely six single volumes and five with three volumes each, i.e. a total of twenty-one volumes. The rational use of medication should be considered an important topic for the promotion of health which affects all sectors of society and should be emphasized in basic education. In line with this idea and based on the results obtained, it is suggested that the textbooks analyzed should be adapted to the new legislation and content that addresses Rational Drug Use, thus meeting the recommendations of PCN+. In this context, the books should concisely address the following topics: self-medication, adherence to drug treatment, advertisements and reports on drugs, among others.

Textbook of respiratory medicine

DOE Office of Scientific and Technical Information (OSTI.GOV)

Murray, J.F.; Nadel, J.

1987-01-01

This book presents a clinical reference of respiratory medicine. It also details basic science aspects of pulmonary physiology and describes recently developed, sophisticated diagnostic tools and therapeutic methods. It also covers anatomy, physiology, pharmacology, and pathology; microbiologic, radiologic, nuclear medicine, and biopsy methods for diagnosis.

Supporting academically-based social studies curriculum standards for the Nation's elementary and secondary education public school textbooks.

THOMAS, 111th Congress

Rep. Johnson, Eddie Bernice [D-TX-30

2010-07-30

House - 10/13/2010 Referred to the Subcommittee on Early Childhood, Elementary, and Secondary Education. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Industrial bronchitis

MedlinePlus

... anatomy Bronchitis and normal condition in tertiary bronchus Respiratory system References Lemière C, Vandenplas O. Asthma in the workplace. In: Broaddus VC, Mason RJ, Ernst JD, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine . 6th ed. Philadelphia, PA: Elsevier Saunders; 2016: ...

Evaluation of time domain and spectral domain optical coherence tomography in the measurement of diabetic macular edema.

PubMed

Forooghian, Farzin; Cukras, Catherine; Meyerle, Catherine B; Chew, Emily Y; Wong, Wai T

2008-10-01

To evaluate macular thickness and volume measurements and their intrasession repeatability in two optical coherence tomography (OCT) systems: the Stratus OCT, a time domain system, and the Cirrus HD-OCT, a spectral domain system (both by Carl Zeiss Meditec, Inc., Dublin, CA), in the context of diabetic macular edema (DME). Thirty-three eyes of 33 diabetic patients with clinically significant macular edema (CSME) were scanned in a single session by a single operator on both OCT systems. Macular thickness measurements of nine standard macular subfields and total macular volume were obtained and analyzed. Bland-Altman plots were constructed to assess agreement in macular measurements. Intraclass correlation coefficients (ICCs), coefficients of repeatability (CR(W)), and coefficients of variation (CV(W)) were used to assess intrasession repeatability. Macular thickness in nine retinal subfields and macular volume were significantly higher in the Cirrus HD-OCT system compared with the Stratus OCT system. Subfield thickness and total volume measurements, respectively, were 30 to 55 microm and 3.2 mm(3) greater for the Cirrus HD-OCT system compared with the Stratus OCT system. Both Stratus OCT and Cirrus HD-OCT systems demonstrated high intrasession repeatability, with overlapping ranges for CR(W), CV(W), and ICC. Repeatability measures (CR(W) and CV(W)) differed significantly between systems in only one of nine subfields (outer temporal subfield). Absolute measures of macular thickness and volume in patients with DME differed significantly in magnitude between the Stratus OCT and Cirrus HD-OCT systems. However, both OCT systems demonstrated high intrasessional repeatability. Although the two systems may not be used interchangeably, they appear equally reliable in generating macular measurements for clinical practice and research.

Analysis of Retinal Thinning Using Spectral-domain Optical Coherence Tomography Imaging of Sickle Cell Retinopathy Eyes Compared to Age- and Race-Matched Control Eyes.

PubMed

Lim, Jennifer I; Cao, Dingcai

2018-03-17

To determine whether the retina is thinner in sickle cell patients than in race- and age-matched controls, and, if it is thinner, whether there is any association with systemic diseases. Sickle cell and control (age- and race-matched) patients were prospectively enrolled from a university retina clinic into this observational study. Participants underwent visual acuity testing, slit-lamp biomicroscopy, dilated ophthalmoscopy, and spectral-domain optical coherence tomography imaging. Sickle cell retinal lesions, degree of vascular tortuosity, caliber of arteriovenous anastomosis, and stage of retinopathy were noted. Early Treatment Diabetic Retinopathy Study (ETDRS) subfield measurements were compared between sickle cell and control subjects and also among sickle cell hemoglobin subtypes. Associations between ETDRS subfield measurements and hemoglobin subtype, retinopathy stage, and systemic diseases were assessed. A total of 513 sickle cell eyes (260 patients) and 75 control eyes (39 patients) had median visual acuities of 20/20. ETDRS central (P = .002), inner (nasal P = .009, superior P = .021, temporal P < .001, inferior P = .017), and temporal outer (P = .012) subfield measurements were thinner in sickle cell eyes compared to control eyes. Hemoglobin SS eyes had significantly thinner inner ETDRS subfield measurements compared to SC and SThal eyes. Retinal thinning in all subfields was associated with age (P = .017) for sickle cell and control eyes. No association was found between retinal thinning and hydroxyurea use or arteriovenous anastomosis caliber. The macula is thinner in sickle cell eyes compared to control eyes; retinal thickness decreases with increasing age and sickle cell retinopathy stage and is most severe in hemoglobin SS subtypes. Copyright © 2018 Elsevier Inc. All rights reserved.

Chronic renal failure induces cell death in rat hippocampal CA1 via upregulation of αCaMKII/NR2A synaptic complex and phosphorylated GluR1-containing AMPA receptor cascades.

PubMed

Kim, Jong Wan; Ha, Gyoung Yim; Jung, Yong Wook

2014-09-01

N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methylisoxazole-4-propinoic acid (AMPA) receptors bound to postsynaptic density-95 (PSD-95) and α isoform of calcium/calmodulin-dependent protein kinase II (αCaMKII) is fundamentally involved in the regulation of working memory. The aim of present study was to investigate the alterations of NMDA and AMPA receptors responsible for hippocampal synaptic dysfunction and selective neuronal cell death after chronic renal failure (CRF) which may be associated with impairment of working memory. Altered interactions between NMDA and AMPA receptors and PSD-95 and αCaMKII were analyzed in the cornu ammonis (CA) 1 and CA3/dentate gyrus (DG) subfields of the uremic rat hippocampi using the immunoblotting and immunoprecipitation methods. Uremia induced by CRF produced necrotic cell death and decreased neuronal nucleoli protein levels in the hippocampal CA1 subfield, but not in the CA3/DG subfields. The CA1 subfields of CRF rats exhibited significant decreases and increases, respectively, in the expressions of PSD-95/NR2B and αCaMKII/NR2A synaptic complex. Moreover, increased phosphorylation of glutamate receptor type 1 (GluR1) AMPA receptor at ser831 was observed in the CA1 subfield after CRF. These hippocampal CA1 neuronal vulnerability may be responsible for memory dysfunction after CRF as mediated by an increase in NR2A-containing NMDA receptors bound to αCaMKII and subsequent activation of GluR1-containing AMPA receptors caused by the phosphorylation of GluR1 at ser831.

Focal CA3 hippocampal subfield atrophy following LGI1 VGKC-complex antibody limbic encephalitis.

PubMed

Miller, Thomas D; Chong, Trevor T-J; Aimola Davies, Anne M; Ng, Tammy W C; Johnson, Michael R; Irani, Sarosh R; Vincent, Angela; Husain, Masud; Jacob, Saiju; Maddison, Paul; Kennard, Christopher; Gowland, Penny A; Rosenthal, Clive R

2017-05-01

Magnetic resonance imaging has linked chronic voltage-gated potassium channel (VGKC) complex antibody-mediated limbic encephalitis with generalized hippocampal atrophy. However, autoantibodies bind to specific rodent hippocampal subfields. Here, human hippocampal subfield (subiculum, cornu ammonis 1-3, and dentate gyrus) targets of immunomodulation-treated LGI1 VGKC-complex antibody-mediated limbic encephalitis were investigated using in vivo ultra-high resolution (0.39 × 0.39 × 1.0 mm3) 7.0 T magnetic resonance imaging [n = 18 patients, 17 patients (94%) positive for LGI1 antibody and one patient negative for LGI1/CASPR2 but positive for VGKC-complex antibodies, mean age: 64.0 ± 2.55 years, median 4 years post-limbic encephalitis onset; n = 18 controls]. First, hippocampal subfield quantitative morphometry indicated significant volume loss confined to bilateral CA3 [F(1,34) = 16.87, P < 0.0001], despite hyperintense signal evident in 5 of 18 patients on presentation. Second, early and later intervention (<3 versus >3 months from symptom onset) were associated with CA3 atrophy. Third, whole-brain voxel-by-voxel morphometry revealed no significant grey matter loss. Fourth, CA3 subfield atrophy was associated with severe episodic but not semantic amnesia for postmorbid autobiographical events that was predicted by variability in CA3 volume. The results raise important questions about the links with histopathology, the impact of the observed focal atrophy on other CA3-mediated reconstructive and episodic mechanisms, and the role of potential antibody-mediated pathogenicity as part of the pathophysiology cascade in humans. © The Author (2017). Published by Oxford University Press on behalf of the Guarantors of Brain.

The Earliest Reference to ADHD in the Medical Literature? Melchior Adam Weikard's Description in 1775 of "Attention Deficit" (Mangel der Aufmerksamkeit, Attentio Volubilis)

ERIC Educational Resources Information Center

Barkley, Russell A.; Peters, Helmut

2012-01-01

Objective: The present article reports on the discovery and translation of a chapter in a 1775 medical textbook by the German physician, Melchior Adam Weikard, which describes attention disorders. This article is believed to be the earliest reference to the syndrome that today is known as attention deficit hyperactivity disorder, or ADHD. Method:…

A harmonized segmentation protocol for hippocampal and parahippocampal subregions: Why do we need one and what are the key goals?

PubMed

Wisse, Laura E M; Daugherty, Ana M; Olsen, Rosanna K; Berron, David; Carr, Valerie A; Stark, Craig E L; Amaral, Robert S C; Amunts, Katrin; Augustinack, Jean C; Bender, Andrew R; Bernstein, Jeffrey D; Boccardi, Marina; Bocchetta, Martina; Burggren, Alison; Chakravarty, M Mallar; Chupin, Marie; Ekstrom, Arne; de Flores, Robin; Insausti, Ricardo; Kanel, Prabesh; Kedo, Olga; Kennedy, Kristen M; Kerchner, Geoffrey A; LaRocque, Karen F; Liu, Xiuwen; Maass, Anne; Malykhin, Nicolai; Mueller, Susanne G; Ofen, Noa; Palombo, Daniela J; Parekh, Mansi B; Pluta, John B; Pruessner, Jens C; Raz, Naftali; Rodrigue, Karen M; Schoemaker, Dorothee; Shafer, Andrea T; Steve, Trevor A; Suthana, Nanthia; Wang, Lei; Winterburn, Julie L; Yassa, Michael A; Yushkevich, Paul A; la Joie, Renaud

2017-01-01

The advent of high-resolution magnetic resonance imaging (MRI) has enabled in vivo research in a variety of populations and diseases on the structure and function of hippocampal subfields and subdivisions of the parahippocampal gyrus. Because of the many extant and highly discrepant segmentation protocols, comparing results across studies is difficult. To overcome this barrier, the Hippocampal Subfields Group was formed as an international collaboration with the aim of developing a harmonized protocol for manual segmentation of hippocampal and parahippocampal subregions on high-resolution MRI. In this commentary we discuss the goals for this protocol and the associated key challenges involved in its development. These include differences among existing anatomical reference materials, striking the right balance between reliability of measurements and anatomical validity, and the development of a versatile protocol that can be adopted for the study of populations varying in age and health. The commentary outlines these key challenges, as well as the proposed solution of each, with concrete examples from our working plan. Finally, with two examples, we illustrate how the harmonized protocol, once completed, is expected to impact the field by producing measurements that are quantitatively comparable across labs and by facilitating the synthesis of findings across different studies. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

The Relationship between the Field-Shifting Phenomenon and Representational Coherence of Place Cells in CA1 and CA3 in a Cue-Altered Environment

ERIC Educational Resources Information Center

Lee, Inah; Knierim, James J.

2007-01-01

Subfields of the hippocampus display differential dynamics in processing a spatial environment, especially when changes are introduced to the environment. Specifically, when familiar cues in the environment are spatially rearranged, place cells in the CA3 subfield tend to rotate with a particular set of cues (e.g., proximal cues), maintaining a…

Optoelectronics-related competence building in Japanese and Western firms

NASA Astrophysics Data System (ADS)

Miyazaki, Kumiko

1992-05-01

In this paper, an analysis is made of how different firms in Japan and the West have developed competence related to optoelectronics on the basis of their previous experience and corporate strategies. The sample consists of a set of seven Japanese and four Western firms in the industrial, consumer electronics and materials sectors. Optoelectronics is divided into subfields including optical communications systems, optical fibers, optoelectronic key components, liquid crystal displays, optical disks, and others. The relative strengths and weaknesses of companies in the various subfields are determined using the INSPEC database, from 1976 to 1989. Parallel data are analyzed using OTAF U.S. patent statistics and the two sets of data are compared. The statistical analysis from the database is summarized for firms in each subfield in the form of an intra-firm technology index (IFTI), a new technique introduced to assess the revealed technology advantage of firms. The quantitative evaluation is complemented by results from intensive interviews with the management and scientists of the firms involved. The findings show that there is a marked variation in the way firms' technological trajectories have evolved giving rise to strength in some and weakness in other subfields for the different companies, which are related to their accumulated core competencies, previous core business activities, organizational, marketing, and competitive factors.

Differential Calculus: Concepts and Notation.

ERIC Educational Resources Information Center

Hobbs, David; Relf, Simon

1997-01-01

Suggests that many students with A-level mathematics, and even with a degree in mathematics or a related subject, do not have an understanding of the basic principles of calculus. Describes the approach used in three textbooks currently in use. Contains 14 references. (Author/ASK)

Teaching Listening.

ERIC Educational Resources Information Center

Mendelsohn, David J.

1998-01-01

Review of research on trends in teaching second-language listening focuses primarily on strategy instruction and a strategy-based approach but also refers to developments in terms of listening and "high-tech contexts," interactive listening, and academic listening. Classroom listening textbooks are discussed, with attention to the mismatch between…

Logic, History, and the Chemistry Textbook: I. Does Chemistry Have a Logical Structure?

ERIC Educational Resources Information Center

Jensen, William B.

1998-01-01

Presents the first of three invited keynote lectures from the 1995 conference of the New England Association of Chemistry Teachers. Discusses the relevance of the history of chemistry to the teaching of chemistry. Contains 27 references. (DDR)

Transcending a Patriarchal Past: Teaching the History of Women in Sociology.

ERIC Educational Resources Information Center

Deegan, Mary Jo

1988-01-01

Contends that the ideas of early female sociologists are rarely documented in textbooks, classrooms, or historical accounts of the profession. Provides a guide to reference works, autobiographies, and biographies about 10 early female founders of American sociology. (Author/BSR)

Textbook presentations of weight: Conceptual difficulties and language ambiguities

NASA Astrophysics Data System (ADS)

Taibu, Rex; Rudge, David; Schuster, David

2015-06-01

The term "weight" has multiple related meanings in both scientific and everyday usage. Even among experts and in textbooks, weight is ambiguously defined as either the gravitational force on an object or operationally as the magnitude of the force an object exerts on a measuring scale. This poses both conceptual and language difficulties for learners, especially for accelerating objects where the scale reading is different from the gravitational force. But while the underlying physical constructs behind the two referents for the term weight (and their relation to each other) are well understood scientifically, it is unclear how the concept of weight should be introduced to students and how the language ambiguities should be dealt with. We investigated treatments of weight in a sample of twenty introductory college physics textbooks, analyzing and coding their content based on the definition adopted, how the distinct constructs were dealt with in various situations, terminologies used, and whether and how language issues were handled. Results indicate that language-related issues, such as different, inconsistent, or ambiguous uses of the terms weight, "apparent weight," and "weightlessness," were prevalent both across and within textbooks. The physics of the related constructs was not always clearly presented, particularly for accelerating bodies such as astronauts in spaceships, and the language issue was rarely addressed. Our analysis of both literature and textbooks leads us to an instructional position which focuses on the physics constructs before introducing the term weight, and which explicitly discusses the associated language issues.

Physics in perspective, volume 1

NASA Technical Reports Server (NTRS)

1972-01-01

Progress in physics and its subfields is presented and the contribution of physics is related to progress in other scientific disciplines and the manner in which these have been utilized by our civilization. The future course of endeavor in the various subfields of physics and the extent to which these will require resources of manpower, facilities, and funding are discussed. The rational responses of the total research effort in physics to alternative funding levels are assayed.

[Neurology in Sanitatis Salernitanum Regimen].

PubMed

Guerrero Peral, A L; de Frutos González, V

2009-04-01

In Salerno, a town in southern Italy, medical influences of Arabs, Jews, Greeks and Romans, synergized to form a medical school during 10th century. Salerno established certification and training method for physicians which contributed to first universities. Regimen Sanitatis Salernitanum is one of Salerno School of Medicine main textbooks. Regimen, also known as Flos medicine, is a medical poem written probably by some Salernitan authors in the second half of the 12th century. Its great later success gave place to a great number of copies that threatened text rigour. In this work we describe the first critical Spanish translation available, resulting from the review of 178 manuscripts. We found many references to neurological diseases in Regimen. The textbook proposes many advices about foods, herbs, or sleep requirements. Nerve diseases, migraine, epilepsy, dizziness, memory complaints, or sensorial deficits are cited. This important medical medieval textbook offers us an interesting perspective about neurological diseases consideration of medieval physician, as well as the main hygienic- dietetic remedies he used to face them.

Hoer-Sprech-Uebungen fuer Iraner (Aural-Oral Exercises for Iranians).

ERIC Educational Resources Information Center

Scharf, Kurt

1980-01-01

Exercises are presented as supplementary material for beginning classes. Many examples illustrate ways to consolidate the learned material, with particular reference to the textbook "Ich lerne Deutsch" and its pictures. Other exercises are designed to compare German and Farsi sentence structure. (IFS/WGA)

Educational Gymnastics: Enhancing Children's Physical Literacy

ERIC Educational Resources Information Center

Baumgarten, Sam; Pagnano-Richardson, Karen

2010-01-01

Virtually all current physical education curriculum guides and textbooks include sections on learner outcomes based on the national standards for physical education, which often refer to gymnastics skills. Gymnastics is a perfect venue for teaching movement concepts, developing and maintaining overall body fitness, fostering personal and social…

English for Specific Purposes. Information Guide 2.

ERIC Educational Resources Information Center

British Council, London (England). English-Teaching Information Centre.

This bibliography of materials for teachers of English for specific purposes lists textbooks, technical readers, articles, resource books, reports, dictionaries, reference books, bibliographies, word frequency lists, catalogues of teaching aids, games and activities, current research in Britain, documents available in the archives of the English…

Pseudohistory and Pseudoscience

NASA Astrophysics Data System (ADS)

Allchin, Douglas

The dangers of pseudoscience - parapsychology, astrology, creationism, etc. - are widely criticized. Lessons in the history of science are often viewed as an educational remedy by conveying the nature of science. But such histories can be flawed. In particular, many stories romanticize scientists, inflate the drama of their discoveries, and oversimplify the process of science. They are, literally and rhetorically, myths. While based on real historical events, they distort the basis of scientific authority and foster unwarranted stereotypes. Such stories are pseudohistory. Like pseudoscience, they promote false ideas about science - in this case, about how science works. Paradoxically, perhaps, the history of pseudosciences may offer an excellent vehicle for remedying such impressions. Characteristically, textbooks of science contain just a bit of history, either in an introductory chapter or, more often, in scattered references to the great heroes of an earlier age. From such references both students and professionals come to feel like participants in a long-standing historical tradition. Yet the textbook-derived tradition in which scientists come to sense their participation is one that, in fact, never existed.

Stepping Stones: Evolving the Earth and Its Life

NASA Astrophysics Data System (ADS)

McKay, Christopher P.

In recent years, science has begun to consider more system-level studies that cross disciplines. These studies challenge our traditional disciplinary training. It is no longer enough to be just a geologist when the problems of interest deal with an entire planet. Indeed, a knowledge of biology, geology astronomy, and myriad subfields is needed. In Stepping Stones, Stephen Drury steps up to the daunting task of writing a general treatment of the science of the entire Earth. He not only ranges through all of the relevant physical sciences but also reaches to economics and political theory. The material is presented at a general level with reading lists but no specific references. Equations have been minimized.

Vitrectomy outcomes in eyes with diabetic macular edema and vitreomacular traction.

PubMed

Haller, Julia A; Qin, Haijing; Apte, Rajendra S; Beck, Roy R; Bressler, Neil M; Browning, David J; Danis, Ronald P; Glassman, Adam R; Googe, Joseph M; Kollman, Craig; Lauer, Andreas K; Peters, Mark A; Stockman, Margaret E

2010-06-01

To evaluate vitrectomy for diabetic macular edema (DME) in eyes with at least moderate vision loss and vitreomacular traction. Prospective cohort study. The primary cohort included 87 eyes with DME and vitreomacular traction based on investigator's evaluation, visual acuity 20/63-20/400, optical coherence tomography (OCT) central subfield >300 microns and no concomitant cataract extraction at the time of vitrectomy. Surgery was performed according to the investigator's usual routine. Follow-up visits were performed after 3 months, 6 months (primary end point), and 1 year. Visual acuity, OCT retinal thickening, and operative complications. At baseline, median visual acuity in the 87 eyes was 20/100 and median OCT thickness was 491 microns. During vitrectomy, additional procedures included epiretinal membrane peeling in 61%, internal limiting membrane peeling in 54%, panretinal photocoagulation in 40%, and injection of corticosteroids at the close of the procedure in 64%. At 6 months, median OCT central subfield thickness decreased by 160 microns, with 43% having central subfield thickness <250 microns and 68% having at least a 50% reduction in thickening. Visual acuity improved by > or =10 letters in 38% (95% confidence interval, 28%-49%) and deteriorated by > or =10 letters in 22% (95% confidence interval, 13%-31%). Postoperative complications through 6 months included vitreous hemorrhage (5 eyes), elevated intraocular pressure requiring treatment (7 eyes), retinal detachment (3 eyes), and endophthalmitis (1 eye). Few changes in results were noted between 6 months and 1 year. After vitrectomy performed for DME and vitreomacular traction, retinal thickening was reduced in most eyes. Between 28% and 49% of eyes with characteristics similar to those included in this study are likely to have improvement of visual acuity, whereas between 13% and 31% are likely to have worsening. The operative complication rate is low and similar to what has been reported for this procedure. These data provide estimates of surgical outcomes and serve as a reference for future studies that might consider vitrectomy for DME in eyes with at least moderate vision loss and vitreomacular traction. Copyright 2010 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

Science Books, A Quarterly Review, Volume 8 Number 3.

ERIC Educational Resources Information Center

American Association for the Advancement of Science, Washington, DC.

This quarterly publication is intended to acquaint students and teachers with new trade books, textbooks, and reference works in the pure and applied sciences. A listing of detailed subject fields is provided including psychology, sociology, economics, education, physical sciences, natural sciences, engineering, agriculture, geography and…

Common Earth Science Misconceptions in Science Teaching

ERIC Educational Resources Information Center

King, Chris

2012-01-01

A survey of the Earth science content of science textbooks found a wide range of misconceptions. These are discussed in this article with reference to the published literature on Earth science misconceptions. Most misconceptions occurred in the "sedimentary rocks and processes" and "Earth's structure and plate tectonics"…

Quantitative and Qualitative Evaluation of Iranian Researchers' Scientific Production in Dentistry Subfields.

PubMed

Yaminfirooz, Mousa; Motallebnejad, Mina; Gholinia, Hemmat; Esbakian, Somayeh

2015-10-01

As in other fields of medicine, scientific production in the field of dentistry has significant placement. This study aimed at quantitatively and qualitatively evaluating Iranian researchers' scientific output in the field of dentistry and determining their contribution in each of dentistry subfields and branches. This research was a scientometric study that applied quantitative and qualitative indices of Web of Science (WoS). Research population consisted of927indexed documents published under the name of Iran in the time span of 1993-2012 which were extracted from WoS on 10 March 2013. The Mann-Whitney test and Pearson correlation coefficient were used to data analyses in SPSS 19. 777 (83. 73%) of indexed items of all scientific output in WoS were scientific articles. The highest growth rate of scientific productionwith90% belonged to endodontic sub field. The correlation coefficient test showed that there was a significant positive relationship between the number of documents and their publication age (P < 0. 0001). There was a significant difference between the mean number of published articles in the first ten- year (1993-2003) and that of the second one (2004-2013), in favor of the latter (P = 0. 001). The distribution frequencies of scientific production in various subfields of dentistry were very different. It needs to reinforce the infrastructure for more balanced scientific production in the field and its related subfields.

Opportunities for Energy Crop Production Based on Subfield Scale Distribution of Profitability

DOE PAGES

Bonner, Ian J.; Cafferty, Kara G.; Muth, Jr., David J.; ...

2014-10-01

Incorporation of dedicated herbaceous energy crops into row crop landscapes is a promising means to supply an expanding biofuel industry while increasing biomass yields, benefiting soil and water quality, and increasing biodiversity. Despite these positive traits energy crops remain largely unaccepted due to concerns over their practicality and cost of implementation. This paper presents a case study on Hardin County, Iowa to demonstrate how subfield decision making can be used to target candidate areas for conversion to energy crop production. The strategy presented integrates switchgrass (Panicum virgatum L.) into subfield landscape positions where corn (Zea mays L.) grain is modeledmore » to operate at a net economic loss. The results of this analysis show that switchgrass integration has the potential to increase sustainable biomass production from 48 to 99% (depending on the rigor of conservation practices applied to corn stover collection) while also improving field level profitability. Candidate land area is highly sensitive to grain price (0.18 to 0.26 US$ kg-1) and dependent on the acceptable net profit for corn production (ranging from 0 to -1,000 US$ ha-1). This work presents the case that switchgrass can be economically implemented into row crop production landscapes when management decisions are applied at a subfield scale and compete against areas of the field operating at a negative net profit.« less

Changes in Search Path Complexity and Length During Learning of a Virtual Water Maze: Age Differences and Differential Associations with Hippocampal Subfield Volumes

PubMed Central

Daugherty, Ana M.; Bender, Andrew R.; Yuan, Peng; Raz, Naftali

2016-01-01

Impairment of hippocampus-dependent cognitive processes has been proposed to underlie age-related deficits in navigation. Animal studies suggest a differential role of hippocampal subfields in various aspects of navigation, but that hypothesis has not been tested in humans. In this study, we examined the association between volume of hippocampal subfields and age differences in virtual spatial navigation. In a sample of 65 healthy adults (age 19–75 years), advanced age was associated with a slower rate of improvement operationalized as shortening of the search path over 25 learning trials on a virtual Morris water maze task. The deficits were partially explained by greater complexity of older adults' search paths. Larger subiculum and entorhinal cortex volumes were associated with a faster decrease in search path complexity, which in turn explained faster shortening of search distance. Larger Cornu Ammonis (CA)1–2 volume was associated with faster distance shortening, but not in path complexity reduction. Age differences in regional volumes collectively accounted for 23% of the age-related variance in navigation learning. Independent of subfield volumes, advanced age was associated with poorer performance across all trials, even after reaching the asymptote. Thus, subiculum and CA1–2 volumes were associated with speed of acquisition, but not magnitude of gains in virtual maze navigation. PMID:25838036

Quantitative and Qualitative Evaluation of Iranian Researchers’ Scientific Production in Dentistry Subfields

PubMed Central

Yaminfirooz, Mousa; Motallebnejad, Mina; Gholinia, Hemmat; Esbakian, Somayeh

2015-01-01

Background: As in other fields of medicine, scientific production in the field of dentistry has significant placement. This study aimed at quantitatively and qualitatively evaluating Iranian researchers’ scientific output in the field of dentistry and determining their contribution in each of dentistry subfields and branches. Methods: This research was a scientometric study that applied quantitative and qualitative indices of Web of Science (WoS). Research population consisted of927indexed documents published under the name of Iran in the time span of 1993-2012 which were extracted from WoS on 10 March 2013. The Mann-Whitney test and Pearson correlation coefficient were used to data analyses in SPSS 19. Results: 777 (83. 73%) of indexed items of all scientific output in WoS were scientific articles. The highest growth rate of scientific productionwith90% belonged to endodontic sub field. The correlation coefficient test showed that there was a significant positive relationship between the number of documents and their publication age (P < 0. 0001). There was a significant difference between the mean number of published articles in the first ten- year (1993-2003) and that of the second one (2004-2013), in favor of the latter (P = 0. 001). Conclusions: The distribution frequencies of scientific production in various subfields of dentistry were very different. It needs to reinforce the infrastructure for more balanced scientific production in the field and its related subfields. PMID:26635439

Relationship between hippocampal subfield volumes and memory deficits in patients with thalamus infarction.

PubMed

Chen, Li; Luo, Tianyou; Lv, Fajin; Shi, Dandan; Qiu, Jiang; Li, Qi; Fang, Weidong; Peng, Juan; Li, Yongmei; Zhang, Zhiwei; Li, Yang

2016-09-01

Clinical studies have shown that thalamus infarction (TI) affects memory function. The thalamic nucleus is directly or indirectly connected to the hippocampal system in animal models. However, this connection has not been investigated using structural magnetic resonance imaging (MRI) in humans. From the pathological perspective, TI patients may serve as valid models for revealing the interaction between the thalamus and hippocampus in memory function. In this study, we aim to assess different hippocampal subfield volumes in TI patients and control subjects using MRI and test their associations with memory function. A total of 37 TI patients (TI group), 38 matched healthy control subjects (HC group), and 22 control patients with other stroke location (SC group) underwent 3.0-T MRI scans and clinical memory examinations. Hippocampal subfield volumes were measured and compared by using FreeSurfer software. We examined the correlation between hippocampal subfield volumes and memory scores. Smaller ipsilesional presubiculum and subiculum volumes were observed, and former was related to graphics recall in both left and right TI patients. The left subiculum volume was correlated with short-delayed recall in left TI patients. The right presubiculum volume was correlated with short- and long-delayed recall in right TI patients. TI was found to result in hippocampal abnormality and memory deficits, and its neural mechanisms might be related with and interaction between the thalamus and hippocampus.

The relevance of hippocampal subfield integrity and clock drawing test performance for the diagnosis of Alzheimer's disease and mild cognitive impairment.

PubMed

Hirjak, Dusan; Sambataro, Fabio; Remmele, Barbara; Kubera, Katharina M; Schröder, Johannes; Seidl, Ulrich; Thomann, Anne K; Maier-Hein, Klaus H; Wolf, Robert C; Thomann, Philipp A

2017-08-31

The clock drawing test (CDT) is one of the worldwide most used screening tests for Alzheimer's disease (AD). MRI studies have identified temporo-parietal regions being involved in CDT impairment. However, the contributions of specific hippocampal subfields and adjacent extrahippocampal structures to CDT performance in AD and mild cognitive impairment (MCI) have not been investigated so far. It is unclear whether morphological alterations or CDT score, or a combination of both, are able to predict AD. 38 AD patients, 38 MCI individuals and 31 healthy controls underwent neuropsychological assessment and MRI at 3 Tesla. FreeSurfer 5.3 was used to perform hippocampal parcellation. We used a collection of statistical methods to better understand the relationship between CDT and hippocampal formation. We also tested the clinical feasibility of this relationship when predicting AD. Impaired CDT performance in AD was associated with widespread atrophy of the cornu ammonis, presubiculum, and subiculum, whereas MCI subjects showed CDT-related alterations of the CA4-dentate gyrus and subiculum. CDT correlates in AD and MCI showed regional and quantitative overlap. Importantly, CDT score was the best predictor of AD. Our findings lend support for an involvement of different hippocampal subfields in impaired CDT performance in AD and MCI. CDT seems to be more efficient than subfield imaging for predicting AD.

Histology-derived volumetric annotation of the human hippocampal subfields in postmortem MRI.

PubMed

Adler, Daniel H; Pluta, John; Kadivar, Salmon; Craige, Caryne; Gee, James C; Avants, Brian B; Yushkevich, Paul A

2014-01-01

Recently, there has been a growing effort to analyze the morphometry of hippocampal subfields using both in vivo and postmortem magnetic resonance imaging (MRI). However, given that boundaries between subregions of the hippocampal formation (HF) are conventionally defined on the basis of microscopic features that often lack discernible signature in MRI, subfield delineation in MRI literature has largely relied on heuristic geometric rules, the validity of which with respect to the underlying anatomy is largely unknown. The development and evaluation of such rules are challenged by the limited availability of data linking MRI appearance to microscopic hippocampal anatomy, particularly in three dimensions (3D). The present paper, for the first time, demonstrates the feasibility of labeling hippocampal subfields in a high resolution volumetric MRI dataset based directly on microscopic features extracted from histology. It uses a combination of computational techniques and manual post-processing to map subfield boundaries from a stack of histology images (obtained with 200μm spacing and 5μm slice thickness; stained using the Kluver-Barrera method) onto a postmortem 9.4Tesla MRI scan of the intact, whole hippocampal formation acquired with 160μm isotropic resolution. The histology reconstruction procedure consists of sequential application of a graph-theoretic slice stacking algorithm that mitigates the effects of distorted slices, followed by iterative affine and diffeomorphic co-registration to postmortem MRI scans of approximately 1cm-thick tissue sub-blocks acquired with 200μm isotropic resolution. These 1cm blocks are subsequently co-registered to the MRI of the whole HF. Reconstruction accuracy is evaluated as the average displacement error between boundaries manually delineated in both the histology and MRI following the sequential stages of reconstruction. The methods presented and evaluated in this single-subject study can potentially be applied to multiple hippocampal tissue samples in order to construct a histologically informed MRI atlas of the hippocampal formation. © 2013 Elsevier Inc. All rights reserved.

16 CFR 3.52 - Appeal from initial decision.

Code of Federal Regulations, 2011 CFR

2011-01-01

... notice shall specify the party or parties against whom the appeal is taken and shall designate the... indicated, the following: (i) A subject index of the matter in the brief, with page references, and a table of cases (alphabetically arranged), textbooks, statutes, and other material cited, with page...

Media Studies: Texts and Supplements.

ERIC Educational Resources Information Center

Curriculum Review, 1979

1979-01-01

The 24 reviews in this article include textbooks on journalism and media studies; multimedia kits on advertising, TV news, reporting, and the "grammar" of media; resources on making ad interpreting films in the classroom; supplements on writing for both print and nonprint media; and professional references on improving visual literacy. (Editor)

Science Books, Volume 10 Number 2.

ERIC Educational Resources Information Center

Wolff, Kathryn, Ed.

This quarterly journal reviews trade books, textbooks, and reference works in the pure and applied sciences for students in elementary and secondary schools and in the first two years of college. Included are selected advanced and professional books useful to students and faculty members. A listing of detailed subject fields is provided including…

Students Do Not Overcome Conceptual Difficulties after Solving 1000 Traditional Problems.

ERIC Educational Resources Information Center

Kim, Eunsook; Pak, Sung-Jae

2002-01-01

Investigates the relationship between traditional physics textbook problem solving and conceptual understanding. Reports that students had many of the well-known conceptual difficulties with basic mechanics and that there was little correlation between the number of problems solved and conceptual understanding. (Contains 21 references.)…

The Integration of Trade Books into the Social Studies Curriculum.

ERIC Educational Resources Information Center

Fuhler, Carol J.

1992-01-01

Safe, noncontroversial social studies textbooks are neither meaningful nor necessary according to many students. As an alternative, teachers can integrate well-written trade books into the social studies curriculum. Well-researched diaries, journals, biographies, and autobiographies should become an integral part of the curriculum. (28 references)…

Biological Soil Crust Web Site

Science.gov Websites

www.soilcrust.org Crust 101 Advanced Gallery References CCERS site Links Biological Soil Crusts Textbook Corrections Level of Development Index Biological soil crusts are the community of organisms , mosses, liverworts and lichens. A Field Guide to Biological Soil Crusts of Western U.S. Drylands: Common

Air Conditioning, Heating, and Refrigeration. Competency-Based Curriculum Manual.

ERIC Educational Resources Information Center

Gourley, Frank A., Jr.

This manual was developed to serve as an aid to administrators and instructors involved with postsecondary air conditioning, heating, and refrigeration programs. The first of six chapters contains general information on program implementation, the curriculum design, facilities and equipment requirements, and textbooks and references. Chapter 2…

The Many Faces of Censorship.

ERIC Educational Resources Information Center

Peck, Richard

1999-01-01

An author of 26 books for young adults writes about different forms of censorship including rewriting history textbooks and parents who censor themselves by not staying in touch with their children. Citing Cormier's "The Chocolate War" and Golding's "Lord of the Flies" and making reference to the Colulmbine school murders, he illustrates the…

Integrability and Chaos: The Classical Uncertainty

ERIC Educational Resources Information Center

Masoliver, Jaume; Ros, Ana

2011-01-01

In recent years there has been a considerable increase in the publishing of textbooks and monographs covering what was formerly known as random or irregular deterministic motion, now referred to as deterministic chaos. There is still substantial interest in a matter that is included in many graduate and even undergraduate courses on classical…

The Reading Skills of Home Economics: Problems and Selected References.

ERIC Educational Resources Information Center

Cranney, A. Garr; And Others

Since most secondary school reading textbooks give home economics only minimal attention, this paper identifies selected information sources in home economics reading skills and in home economics for high school reading specialists. The first portion of the paper discusses eight principle problems that home economics poses for secondary school…

Have the Creationists Already Won? or The Teaching of Faux-Biology.

ERIC Educational Resources Information Center

Firenze, Richard

1997-01-01

Recounts the perspectives of several biologists who believe that evolutionary theory is the key to an understanding of biology. Cites examples from textbooks and educational practices which support the theory that many students develop and maintain misconceptions about evolution due to instruction. Contains 53 references. (DDR)

Advancing Your Career: Concepts of Professional Nursing. Second Edition.

ERIC Educational Resources Information Center

Kearney, Rose

This textbook, intended for registered nurses (RN's) returning to school, is designed to provide practicing RN's with professional concepts to advance their careers. The book contains 22 chapters organized in five sections. Each chapter includes chapter objectives, key terms, key points, chapter exercises, references, and a bibliography. Section I…

An exploration of the extent of inclusion of spirituality and spiritual care concepts in core nursing textbooks.

PubMed

Timmins, Fiona; Murphy, Maryanne; Neill, Freda; Begley, Thelma; Sheaf, Greg

2015-01-01

Holistic care that encompasses a spiritual dimension is an expectation in modern healthcare (Rothman, 2009). Increasing attention is being paid to the role of nurses in providing spiritual care to patients. However nurses lack specific skills and expertise in this area (Lundmark, 2006; Timmins, 2010; RCN, 2011), and the extent to which their undergraduate education prepares them for this role is unclear. There is often an absence of clear direction about what to teach undergraduate nursing students. The extent to which core textbooks direct student studies in this area is not known. There is some evidence that some of these fundamental core textbooks provide insufficient direction (Pesut, 2008), thus gaps in knowledge and care provision in this field could be exacerbated. The aim of this study is to examine the extent to which spiritual care concepts are addressed in core nursing textbooks. Five hundred and forty three books were sampled from the Nursing and Midwifery Core Collection list (UK) (Tomlinsons, 2010) representing 94% of the total (n=580). A survey, the Spirituality Textbook Analysis Tool (STAT), was developed and used to collect data. One hundred and thirty of the books included content related to spirituality and religion. However there was little consistency in the core nursing textbooks with regard to direction for providing spiritual care. Thirty eight percent of the books defined spiritual care and 36% provided an outline of the role of the nurse in providing this. While some books advocated the assessment of patients' spiritual needs (32%) few referred specifically to assessment tools. It is essential that nurses are adequately prepared to address the spiritual needs of patients. While there are numerous spiritual care texts that deal solely with this issue for nurses, there is an argument emerging that core nursing texts used by nursing students ought to encompass spiritual care elements. Lack of specific focus on this field, by these key textbooks might infer that this important element of holistic care is less important than other matters in nursing. True holistic care ought to permeate across textbooks and as such spirituality and spiritual care ought not to be sequestered to specialised texts. Core nursing texts need to be strengthened through consistency of application and inclusion of spirituality and spiritual care where relevant. Copyright © 2014 Elsevier Ltd. All rights reserved.

Pedagogic discourse in introductory classes: Multi-dimensional analysis of textbooks and lectures in biology and macroeconomics

NASA Astrophysics Data System (ADS)

Carkin, Susan

The broad goal of this study is to represent the linguistic variation of textbooks and lectures, the primary input for student learning---and sometimes the sole input in the large introductory classes which characterize General Education at many state universities. Computer techniques are used to analyze a corpus of textbooks and lectures from first-year university classes in macroeconomics and biology. These spoken and written variants are compared to each other as well as to benchmark texts from other multi-dimensional studies in order to examine their patterns, relations, and functions. A corpus consisting of 147,000 words was created from macroeconomics and biology lectures at a medium-large state university and from a set of nationally "best-selling" textbooks used in these same introductory survey courses. The corpus was analyzed using multi-dimensional methodology (Biber, 1988). The analysis consists of both empirical and qualitative phases. Quantitative analyses are undertaken on the linguistic features, their patterns of co-occurrence, and on the contextual elements of classrooms and textbooks. The contextual analysis is used to functionally interpret the statistical patterns of co-occurrence along five dimensions of textual variation, demonstrating patterns of difference and similarity with reference to text excerpts. Results of the analysis suggest that academic discourse is far from monolithic. Pedagogic discourse in introductory classes varies by modality and discipline, but not always in the directions expected. In the present study the most abstract texts were biology lectures---more abstract than written genres of academic prose and more abstract than introductory textbooks. Academic lectures in both disciplines, monologues which carry a heavy informational load, were extremely interactive, more like conversation than academic prose. A third finding suggests that introductory survey textbooks differ from those used in upper division classes by being relatively less marked for information density, abstraction, and non-overt argumentation. In addition to the findings mentioned here, numerous other relationships among the texts exhibit complex patterns of variation related to a number of situational variables. Pedagogical implications are discussed in relation to General Education courses, differing student populations, and the reading and listening demands which students encounter in large introductory classes in the university.

Reminder about potentially serious problems with a type of blocked ANOVA analysis

Treesearch

Steve Verrill; David E. Kretschmann

2017-01-01

A type of blocked experiment has the potential of being poorly designed and/or analyzed. Verrill (1993, 1999) and Verrill et al. (2004) referred to such an experiment as a “predictor sort” experiment. David and Gunnink (1997) described the procedure as “artificial pairing.” In textbooks it is sometimes referred to as a “matched pair” or a “matched...

Telecommunications Systems Design Techniques Handbook

NASA Technical Reports Server (NTRS)

Edelson, R. E. (Editor)

1972-01-01

The Deep Space Network (DSN) increasingly supports deep space missions sponsored and managed by organizations without long experience in DSN design and operation. The document is intended as a textbook for those DSN users inexperienced in the design and specification of a DSN-compatible spacecraft telecommunications system. For experienced DSN users, the document provides a reference source of telecommunication information which summarizes knowledge previously available only in a multitude of sources. Extensive references are quoted for those who wish to explore specific areas more deeply.

Alterations in Retinal Layer Thickness and Reflectance at Different Stages of Diabetic Retinopathy by En Face Optical Coherence Tomography

PubMed Central

Wanek, Justin; Blair, Norman P.; Chau, Felix Y.; Lim, Jennifer I.; Leiderman, Yannek I.; Shahidi, Mahnaz

2016-01-01

Purpose This article reports a method for en face optical coherence tomography (OCT) imaging and quantitative assessment of alterations in both thickness and reflectance of individual retinal layers at different stages of diabetic retinopathy (DR). Methods High-density OCT raster volume scans were acquired in 29 diabetic subjects divided into no DR (NDR) or non-proliferative DR (NPDR) groups and 22 control subjects (CNTL). A customized image segmentation method identified eight retinal layer interfaces and generated en face thickness maps and reflectance images for nerve fiber layer (NFL), ganglion cell and inner plexiform layers (GCLIPL), inner nuclear layer (INL), outer plexiform layer (OPL), outer nuclear layer (ONL), photoreceptor outer segment layer (OSL), and retinal pigment epithelium (RPE). Mean thickness and intensity values were calculated in nine macular subfields for each retinal layer. Results En face thickness maps and reflectance images of retinal layers in CNTL subjects corresponded to normal retinal anatomy. Total retinal thickness correlated negatively with age in nasal subfields (R ≤−0.31; P ≤ 0.03, N = 51). In NDR subjects, NFL and OPL thickness were decreased (P = 0.05), and ONL thickness was increased (P = 0.04) compared to CNTL. In NPDR subjects, GCLIPL thickness was increased in perifoveal subfields (P < 0.05) and INL intensity was higher in all macular subfields (P = 0.04) compared to CNTL. Conclusions Depth and spatially resolved retinal thickness and reflectance measurements are potential biomarkers for assessment and monitoring of DR. PMID:27409491

Changes in Search Path Complexity and Length During Learning of a Virtual Water Maze: Age Differences and Differential Associations with Hippocampal Subfield Volumes.

PubMed

Daugherty, Ana M; Bender, Andrew R; Yuan, Peng; Raz, Naftali

2016-06-01

Impairment of hippocampus-dependent cognitive processes has been proposed to underlie age-related deficits in navigation. Animal studies suggest a differential role of hippocampal subfields in various aspects of navigation, but that hypothesis has not been tested in humans. In this study, we examined the association between volume of hippocampal subfields and age differences in virtual spatial navigation. In a sample of 65 healthy adults (age 19-75 years), advanced age was associated with a slower rate of improvement operationalized as shortening of the search path over 25 learning trials on a virtual Morris water maze task. The deficits were partially explained by greater complexity of older adults' search paths. Larger subiculum and entorhinal cortex volumes were associated with a faster decrease in search path complexity, which in turn explained faster shortening of search distance. Larger Cornu Ammonis (CA)1-2 volume was associated with faster distance shortening, but not in path complexity reduction. Age differences in regional volumes collectively accounted for 23% of the age-related variance in navigation learning. Independent of subfield volumes, advanced age was associated with poorer performance across all trials, even after reaching the asymptote. Thus, subiculum and CA1-2 volumes were associated with speed of acquisition, but not magnitude of gains in virtual maze navigation. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

The Clinical Features of Paranoia in the 20th Century and Their Representation in Diagnostic Criteria From DSM-III Through DSM-5

PubMed Central

2017-01-01

Abstract This review traces, through psychiatric textbooks, the history of the Kraepelinian concept of paranoia in the 20th century and then relates the common reported symptoms and signs to the diagnostic criteria for paranoia/delusional disorder in DSM-III through DSM-5. Clinical descriptions of paranoia appearing in 10 textbooks, published 1899 to 1970, revealed 11 prominent symptoms and signs reported by 5 or more authors. Three symptoms (systematized delusions, minimal hallucinations, and prominent ideas of reference) and 2 signs (chronic course and minimal affective deterioration) were reported by 8 or 9 of the authors. Four textbook authors rejected the Kraepelinian concept of paranoia. A weak relationship was seen between the frequency with which the clinical features were reported and the likelihood of their inclusion in modern DSM manuals. Indeed, the diagnostic criteria for paranoia/delusional disorder shifted substantially from DSM-III to DSM-5. The modern operationalized criteria for paranoia/delusional disorder do not well reflect the symptoms and signs frequently reported by historical experts. In contrast to results of similar reviews for depression, schizophrenia and mania, the clinical construct of paranoia/delusional disorder has been somewhat unstable in Western Psychiatry since the turn of the 20th century as reflected in both textbooks and the DSM editions. PMID:28003468

Relationships between Digestive, Circulatory, and Urinary Systems in Portuguese Primary Textbooks

ERIC Educational Resources Information Center

Carvalho, Graça S.; Clèment, Pierre

2007-01-01

In this study, 63 Portuguese primary schoolbooks (1920-2005) were analyzed. The analysis focused on text information (reference to blood absorption and association of the digestive system to other human systems) and on information from images (presence or absence of image "confusion" (when the sequence of the digestive tract is not…

Science Books, A Quarterly Review, Volume 6 Number 4.

ERIC Educational Resources Information Center

Deason, Hilary J.

1971-01-01

For the improvement of science education and to facilitate the public understanding of science, the American Association for the Advancement of Science publishes this quarterly review of science books. Evaluations and annotations are given for trade books, textbooks, and reference works in the pure and applied sciences. Books are for students in…

Science Books, Vol. 9, No. 3.

ERIC Educational Resources Information Center

Wolff, Kathryn, Ed.

This quarterly publication contains reviews of trade books, textbooks, and reference works in the pure and applied sciences which are intended for students in the elementary and secondary schools and in the first two years of college. In addition, books on scientific topics intended for the general reader are reviewed, as are selected advanced and…

Science Books, Vol. 9, No. 2.

ERIC Educational Resources Information Center

Wolff, Kathryn, Ed.

This quarterly publication contains reviews of trade books, textbooks, and reference works in the pure and applied sciences which are intended for students in the elementary and secondary schools and in the first two years of college. In addition, books on scientific topics intended for the general reader are reviewed, as are selected advanced and…

Science Books, Volume 9 Number 4.

ERIC Educational Resources Information Center

Wolff, Kathryn, Ed.

This quarterly publication of the American Association for the Advancement of Science contains reviews of trade books, textbooks, and reference works in the pure and applied sciences which are intended for students in the elementary and secondary schools and in the first two years of college. In addition, books on scientific topics intended for…

Education Law. Course Outline. Casenote Education Series.

ERIC Educational Resources Information Center

Aquila, Frank D.

The material included in this book--case briefs, outlines, and textbook/treatise reference information--provides a summary of the most important aspects of the law regarding education. At the heart of this body of knowledge, commonly identified as education law or school law, is statutory and case law. The book serves as a comprehensive guide to…

Ultrasonic Testing, Aviation Quality Control (Advanced): 9227.03.

ERIC Educational Resources Information Center

Dade County Public Schools, Miami, FL.

This unit of instruction covers the theory of ultrasonic sound, methods of applying soundwaves to test specimens and interpreting results, calibrating the ultrasonic equipment, and the use of standards. Study periods, group discussions, and extensive use of textbooks and training manuals are to be used. These are listed along with references and…

Above and Beyond: A Teacher Selected Bibliography of Instructional Materials for Use with Gifted and Talented Students.

ERIC Educational Resources Information Center

Montgomery County Public Schools, Rockville, MD.

The bibliography includes references to approximately 1500 instructional materials for use with gifted and talented students. Entries usually include author's name, title, availability information and a brief annotation for the following areas (sample subtopics in parentheses): aesthetic education (recommended art and music textbooks); English…

Early Nineteenth Century Christian Libertarian Newspapers: Rise and Decline of the Boston Recorder, 1816-1849.

ERIC Educational Resources Information Center

Olasky, Marvin N.

Recent history textbooks have conspicuously removed references to religion and religious publications, providing a distorted view of American and world history. One such neglected publication, the Boston "Recorder," was founded by Nathaniel Willis in 1816. A Christian newspaper, it was based on three principles: (1) to show theological…

An Introduction to the Profession of Medical Technology. Second Edition.

ERIC Educational Resources Information Center

Williams, M. Ruth; Lindberg, David S.

The publication, intended primarily as a textbook for an introductory course in medical technology, also contains information useful to high school and junior college guidance counselors and of interest to medical technologists as a reference on the historical background of the profession. The book first defines medical technology and then…

WSGB: A Web Service-Based Growing Book

ERIC Educational Resources Information Center

Dow, C. R.; Huang, L. H.; Chen, K. H.; Chiu, J. C.; Lin, C. M.

2006-01-01

Growing Book refers to an electronic textbook that is co-developed, and has the ability to be constantly maintained, by groups of independent authors, thus creating a rich and ever-growing learning environment that can be conveniently accessible from anywhere. This work designs and implements a Web Service-based Growing Book that has the merits of…

Eastern Europe in Western Civilization Textbooks: The Example of Poland

ERIC Educational Resources Information Center

Kulczycki, John J.

2005-01-01

Over a decade ago the newsletter of the American Historical Association "Perspectives" carried a long lead article entitled "Teaching 'Eastern Europe' without the Iron Curtain." Referring to the challenge posed by the revolutions of 1989 in Eastern Europe to the teaching of European history, the author, Larry Wolff, saw it as…

Web Supplement to "Teaching Chain-Weight Real GDP Measures."

ERIC Educational Resources Information Center

Cahill, Miles B.

2003-01-01

Describes a Web site that is a companion to the Miles Cahill article, "Teaching Chain-Weight Real GDP Measures." States that the exercises are useful because intermediate level textbooks treat this topic casually. Indicates that the Web site contains the comment tool, an overview of the concepts, and links to article references. (JEH)

Operation of Wastewater Treatment Plants, Manual of Practice No. 11.

ERIC Educational Resources Information Center

Albertson, Orrie E.; And Others

This book is intended to be a reference or textbook on the operation of wastewater treatment plants. The book contains thirty-one chapters and three appendices and includes the description, requirements, and latest techniques of conventional unit process operation, as well as the symptoms and corrective measures regarding process problems. Process…

Picturing Quantum Processes

NASA Astrophysics Data System (ADS)

Coecke, Bob; Kissinger, Aleks

2017-03-01

Preface; 1. Introduction; 2. Guide to reading this textbook; 3. Processes as diagrams; 4. String diagrams; 5. Hilbert space from diagrams; 6. Quantum processes; 7. Quantum measurement; 8. Picturing classical-quantum processes; 9. Picturing phases and complementarity; 10. Quantum theory: the full picture; 11. Quantum foundations; 12. Quantum computation; 13. Quantum resources; 14. Quantomatic; Appendix A. Some notations; References; Index.

Apollo-Soyuz Pamphlet No. 4: Gravitational Field. Apollo-Soyuz Experiments in Space.

ERIC Educational Resources Information Center

Page, Lou Williams; Page, Thornton

This booklet is the fourth in a series of nine that describe the Apollo-Soyuz mission and experiments. This set is designed as a curriculum supplement for teachers, supervisors, curriculum specialists, textbook writers, and the general public. These booklets provide sources of ideas, examples of the scientific method, references to standard…

The Problems of Tertiary Publishing in Africa and Implications for Training and Education of Library and Information Professionals.

ERIC Educational Resources Information Center

Aina, L. O.

1999-01-01

Discusses the lack of appropriate textbooks for African library and information professional training and suggests the need for team authorship, publishing incentives, support by professional associations, the involvement of retired professionals in marketing and distribution, and the involvement of the governments. (Contains 16 references.) (LRW)

SMALL CRAFT OPERATION AND NAVIGATION.

ERIC Educational Resources Information Center

Louisiana State Dept. of Education, Baton Rouge.

THIS REFERENCE TEXTBOOK WAS PREPARED FOR USE IN THE FIRST PART OF A TWO-PART COURSE IN MARINE NAVIGATION AND SMALL CRAFT OPERATION ON INLAND AND INTERNATIONAL WATERS. THE MATERIAL WAS DEVELOPED BY AN INDIVIDUAL AUTHOR FOR USE IN TRADE SCHOOL PREPARATORY AND EXTENSION CLASSES FOR MALE ADULTS WHO PLAN TO OPERATE BOATS. IT IS MAINLY CONCERNED WITH…

Society and Social Justice: Problems of Political Education in West Germany.

ERIC Educational Resources Information Center

George, Siegfried

1981-01-01

Discusses social justice in West Germany within the context of the experience of Nazism, the economic disaster after World War II, and the successful development of the economy and welfare state since 1949. Refers to various textbooks and recent empirical studies on the political attitudes of students in West Germany. (Author/KC)

Selected References and Aids for Teaching Animal Science to Students of Agricultural Education.

ERIC Educational Resources Information Center

Miller, Larry E.

The resource guide for animal science education is divided into six subject areas: general animal science, beef, dairy, poultry, sheep, and swine. Within each of these areas, the guide provides bibliographic and availability data for relevant materials in the following forms: bulletins and circulars; textbooks; films, filmstrips, and slides; and…

Food Recommendations in Domestic Education, Belgium 1890-1940

ERIC Educational Resources Information Center

Scholliers, Peter

2013-01-01

This paper addresses the question of dissemination of nutritional knowledge in textbooks of household schools between 1890 and 1940. It starts by considering the nature of food recommendations in manuals that are used in Belgian household schools, and then deals with the sources that are referred to by those who give food advice, comparing the…

The Regionalization of Africa in Undergraduate Geography of Africa Textbooks, 1953 to 2004

ERIC Educational Resources Information Center

Cole, Roy

2008-01-01

This study examines the regionalization of Africa through analysis of forty-two English-language geography of Africa texts written for undergraduates between 1953 and 2004. Authors identify regions with reference to one or more variables. Some authors provided no explanation for their regionalization; others labored mightily to justify their…

Apollo-Soyuz Pamphlet No. 1: The Flight. Apollo-Soyuz Experiments in Space.

ERIC Educational Resources Information Center

Page, Lou Williams; Page, Thornton

This is the first in a series of nine booklets that discuss the Apollo-Soyuz mission and experiments. This set is designed as a curriculum supplement for teachers, supervisors, curriculum specialists, textbook writers, and the general public. These booklets provide sources of ideas, examples of the scientific method, references to standard…

Identity as Immunology: History Teaching in Two Ethnonational Borders of Europe

ERIC Educational Resources Information Center

Klerides, Eleftherios; Zembylas, Michalinos

2017-01-01

The power of local borders to resist and prevent transnational mobilities in education has received little attention in comparative education. In this article we explore the motif of "border immunology' with reference to new history, a mobile paradigm of history teaching, and Greek-Cypriot and Turkish-Cypriot history textbooks as types of…

Bibliography of Law-Related Curriculum Materials: Annotated (Second Edition). Working Notes No. 10.

ERIC Educational Resources Information Center

Davison, Susan E., Ed.

This annotated bibliography cites over 1,000 elementary- and secondary-level materials dealing with the philosophy, substance, and pedagogy of law-related education. It lists textbooks, curriculum kits and guides, journals and newsletters, and books that can serve as reference or supplementary materials. The bibliography is divided by topic into…

Chloride: the queen of electrolytes?

PubMed

Berend, Kenrick; van Hulsteijn, Leonard Hendrik; Gans, Rijk O B

2012-04-01

Channelopathies, defined as diseases that are caused by mutations in genes encoding ion channels, are associated with a wide variety of symptoms and have been documented extensively over the past decade. In contrast, despite the important role of chloride in serum, textbooks in general do not allocate chapters exclusively on hypochloremia or hyperchloremia and information on chloride other than channelopathies is scattered in the literature. To systematically review the function of chloride in man, data for this review include searches of MEDLINE, PubMed, and references from relevant articles including the search terms "chloride," "HCl," "chloride channel" "acid-base," "acidosis," "alkalosis," "anion gap" "strong anion gap" "Stewart," "base excess" and "lactate." In addition, internal medicine, critical care, nephrology and gastroenterology textbooks were evaluated on topics pertaining the assessment and management of acid-base disorders, including reference lists from journals or textbooks. Chloride is, after sodium, the most abundant electrolyte in serum, with a key role in the regulation of body fluids, electrolyte balance, the preservation of electrical neutrality, acid-base status and it is an essential component for the assessment of many pathological conditions. When assessing serum electrolytes, abnormal chloride levels alone usually signify a more serious underlying metabolic disorder, such as metabolic acidosis or alkalosis. Chloride is an important component of diagnostic tests in a wide array of clinical situations. In these cases, chloride can be tested in sweat, serum, urine and feces. Abnormalities in chloride channel expression and function in many organs can cause a range of disorders. Copyright © 2011 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.

Peroxisome proliferator-activated receptors γ/mitochondrial uncoupling protein 2 signaling protects against seizure-induced neuronal cell death in the hippocampus following experimental status epilepticus

PubMed Central

2012-01-01

Background Status epilepticus induces subcellular changes that may lead to neuronal cell death in the hippocampus. However, the mechanism of seizure-induced neuronal cell death remains unclear. The mitochondrial uncoupling protein 2 (UCP2) is expressed in selected regions of the brain and is emerged as an endogenous neuroprotective molecule in many neurological disorders. We evaluated the neuroprotective role of UCP2 against seizure-induced hippocampal neuronal cell death under experimental status epilepticus. Methods In Sprague–Dawley rats, kainic acid (KA) was microinjected unilaterally into the hippocampal CA3 subfield to induce prolonged bilateral seizure activity. Oxidized protein level, translocation of Bcl-2, Bax and cytochrome c between cytosol and mitochondria, and expression of peroxisome proliferator-activated receptors γ (PPARγ) and UCP2 were examined in the hippocampal CA3 subfield following KA-induced status epilepticus. The effects of microinjection bilaterally into CA3 area of a PPARγ agonist, rosiglitazone or a PPARγ antagonist, GW9662 on UCP2 expression, induced superoxide anion (O2· -) production, oxidized protein level, mitochondrial respiratory chain enzyme activities, translocation of Bcl-2, Bax and cytochrome c, and DNA fragmentation in bilateral CA3 subfields were examined. Results Increased oxidized proteins and mitochondrial or cytosol translocation of Bax or cytochrome c in the hippocampal CA3 subfield was observed 3–48 h after experimental status epilepticus. Expression of PPARγ and UCP2 increased 12–48 h after KA-induced status epilepticus. Pretreatment with rosiglitazone increased UCP2 expression, reduced protein oxidation, O2· - overproduction and dysfunction of mitochondrial Complex I, hindered the translocation of Bax and cytochrome c, and reduced DNA fragmentation in the CA3 subfield. Pretreatment with GW9662 produced opposite effects. Conclusions Activation of PPARγ upregulated mitochondrial UCP2 expression, which decreased overproduction of reactive oxygen species, improved mitochondrial Complex I dysfunction, inhibited mitochondrial translocation of Bax and prevented cytosolic release of cytochrome c by stabilizing the mitochondrial transmembrane potential, leading to amelioration of apoptotic neuronal cell death in the hippocampus following status epilepticus. PMID:22849356

Novel encoding and updating of positional, or directional, spatial cues are processed by distinct hippocampal subfields: Evidence for parallel information processing and the "what" stream.

PubMed

Hoang, Thu-Huong; Aliane, Verena; Manahan-Vaughan, Denise

2018-05-01

The specific roles of hippocampal subfields in spatial information processing and encoding are, as yet, unclear. The parallel map theory postulates that whereas the CA1 processes discrete environmental features (positional cues used to generate a "sketch map"), the dentate gyrus (DG) processes large navigation-relevant landmarks (directional cues used to generate a "bearing map"). Additionally, the two-streams hypothesis suggests that hippocampal subfields engage in differentiated processing of information from the "where" and the "what" streams. We investigated these hypotheses by analyzing the effect of exploration of discrete "positional" features and large "directional" spatial landmarks on hippocampal neuronal activity in rats. As an indicator of neuronal activity we measured the mRNA induction of the immediate early genes (IEGs), Arc and Homer1a. We observed an increase of this IEG mRNA in CA1 neurons of the distal neuronal compartment and in proximal CA3, after novel spatial exploration of discrete positional cues, whereas novel exploration of directional cues led to increases in IEG mRNA in the lower blade of the DG and in proximal CA3. Strikingly, the CA1 did not respond to directional cues and the DG did not respond to positional cues. Our data provide evidence for both the parallel map theory and the two-streams hypothesis and suggest a precise compartmentalization of the encoding and processing of "what" and "where" information occurs within the hippocampal subfields. © 2018 The Authors. Hippocampus Published by Wiley Periodicals, Inc.

Subfield profitability analysis reveals an economic case for cropland diversification

NASA Astrophysics Data System (ADS)

Brandes, E.; McNunn, G. S.; Schulte, L. A.; Bonner, I. J.; Muth, D. J.; Babcock, B. A.; Sharma, B.; Heaton, E. A.

2016-01-01

Public agencies and private enterprises increasingly desire to achieve ecosystem service outcomes in agricultural systems, but are limited by perceived conflicts between economic and ecosystem service goals and a lack of tools enabling effective operational management. Here we use Iowa—an agriculturally homogeneous state representative of the Maize Belt—to demonstrate an economic rationale for cropland diversification at the subfield scale. We used a novel computational framework that integrates disparate but publicly available data to map ˜3.3 million unique potential management polygons (9.3 Mha) and reveal subfield opportunities to increase overall field profitability. We analyzed subfield profitability for maize/soybean fields during 2010-2013—four of the most profitable years in recent history—and projected results for 2015. While cropland operating at a loss of US 250 ha-1 or more was negligible between 2010 and 2013 at 18 000-190 000 ha (<2% of row-crop land), the extent of highly unprofitable land increased to 2.5 Mha, or 27% of row-crop land, in the 2015 projection. Aggregation of these areas to the township level revealed ‘hotspots’ for potential management change in Western, Central, and Northeast Iowa. In these least profitable areas, incorporating conservation management that breaks even (e.g., planting low-input perennials), into low-yielding portions of fields could increase overall cropland profitability by 80%. This approach is applicable to the broader region and differs substantially from the status quo of ‘top-down’ land management for conservation by harnessing private interest to align profitability with the production of ecosystem services.

Integrative understanding of macular morphologic patterns in diabetic retinopathy based on self-organizing map.

PubMed

Murakami, Tomoaki; Ueda-Arakawa, Naoko; Nishijima, Kazuaki; Uji, Akihito; Horii, Takahiro; Ogino, Ken; Yoshimura, Nagahisa

2014-03-28

To integrate parameters on spectral-domain optical coherence tomography (SD-OCT) in diabetic retinopathy (DR) based on the self-organizing map and objectively describe the macular morphologic patterns. A total of 336 consecutive eyes of 216 patients with DR for whom clear SD-OCT images were available were retrospectively reviewed. Eleven OCT parameters and the logarithm of the minimal angle of resolution (logMAR) were measured. These multidimensional data were analyzed based on the self-organizing map on which similar cases were near each other according to the degree of their similarities, followed by the objective clustering. Self-organizing maps indicated that eyes with greater retinal thickness in the central subfield had greater thicknesses in the superior and temporal subfields. Eyes with foveal serous retinal detachment (SRD) had greater thickness in the nasal or inferior subfield. Eyes with foveal cystoid spaces were arranged to the left upper corner on the two-dimensional map; eyes with foveal SRD to the left lower corner; eyes with thickened retinal parenchyma to the lower area. The following objective clustering demonstrated the unsupervised pattern recognition of macular morphologies in diabetic macular edema (DME) as well as the higher-resolution discrimination of DME per se. Multiple regression analyses showed better association of logMAR with retinal thickness in the inferior subfield in eyes with SRD and with external limiting membrane disruption in eyes with foveal cystoid spaces or thickened retinal parenchyma. The self-organizing map facilitates integrative understanding of the macular morphologic patterns and the structural/functional relationship in DR.

Emergency Medical Care. A Manual for the Paramedic in the Field.

ERIC Educational Resources Information Center

National Highway Traffic Safety Administration (DOT), Washington, DC.

This document is a textbook of emergency medical procedures to be used for training emergency medical technicians. The book is organized into 15 modules, each containing 1 to 10 units. Each module contains information illustrated with line drawings, a glossary, and references. The modules cover the following topics: the role of the emergency…

Science Books, A Quarterly Review, Volume 8 Number 2.

ERIC Educational Resources Information Center

American Association for the Advancement of Science, Washington, DC.

This quarterly journal reviews books in different science fields which could be used by teachers in elementary school, secondary school, and in the first two years of college. Not only are the textbooks reviewed, but trade books and reference works in pure and applied sciences are included. Annotations are listed in order of Dewey Decimal…

A Critical Approach to School Mathematical Knowledge: The Case of "Realistic" Problems in Greek Primary School Textbooks for Seven-Year-Old Pupils

ERIC Educational Resources Information Center

Zacharos, Konstantinos; Koustourakis, Gerassimos

2011-01-01

The reference contexts that accompany the "realistic" problems chosen for teaching mathematical concepts in the first school grades play a major educational role. However, choosing "realistic" problems in teaching is a complex process that must take into account various pedagogical, sociological and psychological parameters.…

Annotated Bibliography of Textbooks and Reference Materials in Marine Sciences. Provisional Edition. Intergovernmental Oceanographic Commission, Technical Series.

ERIC Educational Resources Information Center

United Nations Educational, Scientific, and Cultural Organization, Paris (France). Intergovernmental Oceanographic Commission.

Presented is an annotated bibliography based on selected materials from a preliminary survey of existing bibliographies, publishers' listings, and other sources. It is intended to serve educators and researchers, especially those in countries where marine sciences are just developing. One hundred annotated and 450 non-annotated entries are…

Healthy Young Children: A Manual for Programs, 4th Edition.

ERIC Educational Resources Information Center

Aronson, Susan S., Ed.

Noting that the health component of child care should be planned to respond to the developmental patterns of young children, this manual was developed as a reference and resource guide for program directors and teachers of young children and can be used as a textbook for adult learners. The manual, based on national standards and reviewed by…

The Dutch Are Missing in the American Curriculum

ERIC Educational Resources Information Center

Claunch, Ann

2009-01-01

The Dutch are missing in any U.S. history textbook, in the content standards, and in the nationally endorsed curriculum. Outside of New York State history classes, there is almost no mention of the Dutch influence in early 17th-century America. Fleeting references to the Netherlands as a staging area for the Pilgrims' famous "Mayflower"…

Glass Doesn't Flow and Doesn't Crystallize and It Isn't a Liquid.

ERIC Educational Resources Information Center

Hawkes, Stephen J.

2000-01-01

Illustrates that, contrary to some assertions made in the popular press, scientific literature, and introductory textbooks, glass does not flow in historic time. Contends that glass is a rigid solid with a lower degree of molecular order than a crystal but with greater molecular order than a liquid. (Contains 27 references.) (WRM)

Images of Australia in Elementary Social Studies Texts: Some Alternative Strategies.

ERIC Educational Resources Information Center

Birchall, Gregory; Faichney, Gavin

Elementary social studies textbooks in the United States were analyzed to determine the sort of information they contained about Australia. Only those texts which made substantive references to Australia were analyzed; these included 4 books for level 3, 2 for level 4, and 4 for level 6. Books examined were all published by major textbook…

How Does the "Digital Generation" Get Help on Their Mathematics Homework?

ERIC Educational Resources Information Center

van de Sande, Carla; Boggess, May; Hart-Weber, Catherine

2013-01-01

Homework is a daily activity for at least twelve years of most students' school experience, and every assignment requires the time, energy, and emotional engagement of all those involved. Traditionally, students seeking homework help could refer to their class notes and textbooks, or ask their friends, tutors, and, perhaps, as last resort, their…

The Role Foreign Language Texts Play in Limiting Communication and Understanding.

ERIC Educational Resources Information Center

Van Houten, Jacqueline

Four first-year secondary school commercial French textbooks were analyzed for the number and type of pictorial references to diversity in race, class, and gender, with particular attention given to how French-speaking countries other than France are portrayed. It is concluded that while some of the books represented a pluralistic society better…

Feline arrhythmias: an update.

PubMed

Côté, Etienne

2010-07-01

In the cat, electrocardiography is indicated for assessing the rhythm of the heartbeat and identifying and monitoring the effect of certain systemic disorders on the heart. Basic information regarding feline electrocardiography is contained in several textbooks, and the reader is referred to these sources for background reading. This article describes selected clinical advances in feline cardiac arrhythmias and electrocardiography from the past decade.

Career Awareness Units, Magnolia Public Schools, Grades 1-7.

ERIC Educational Resources Information Center

Magnolia School District 14, AR.

The guide contains career awareness units for grades one through seven. A chart for each grade level lists the unit titles with textbook references, resource speakers, and study trips. Some of the speakers and study trips suggested throughout the guide are specific to the local area. For each unit, concepts to be developed are coordinated in chart…

How Do the German and Dutch Curriculum Contexts Influence (the Use of) Geography Textbooks?

ERIC Educational Resources Information Center

Krause, Uwe; Béneker, Tine; van Tartwijk, Jan; Uhlenwinkel, Anke; Bolhuis, Sanneke

2017-01-01

Bernstein describes a curriculum context as a system context that is regulated by strong and weak framing, which refers to the "degree of control teachers and pupils possess over the selection, organisation, pacing and timing of the knowledge transmitted and received in the pedagogical relationship" (1975, p. 89). In this article, we…

Human Rights Education in Social Studies in the Netherlands: A Case Study Textbook Analysis

ERIC Educational Resources Information Center

de Kort, Frauke

2017-01-01

Citizenship education is one of the main aims of the mandated subject of social studies in secondary schools in the Netherlands. Moreover, the learning outcomes of social studies refer to constitutional rights. Internationally, citizenship education and human rights education are considered to be mutually reinforcing. One may, thus, expect that…

Expressing Disagreement in ELF Business Negotiations: Theory and Practice

ERIC Educational Resources Information Center

Bjorge, Anne Kari

2012-01-01

English spoken by those who do not share their first language is increasingly referred to as English lingua franca (ELF). For ELF speakers, it can be a challenge to express conflicting opinions, as a common language and/or cultural background cannot be taken for granted. This is recognized by writers of business English textbooks, who provide…

[Sub-field imaging spectrometer design based on Offner structure].

PubMed

Wu, Cong-Jun; Yan, Chang-Xiang; Liu, Wei; Dai, Hu

2013-08-01

To satisfy imaging spectrometers's miniaturization, lightweight and large field requirements in space application, the current optical design of imaging spectrometer with Offner structure was analyzed, and an simple method to design imaging spectrometer with concave grating based on current ways was given. Using the method offered, the sub-field imaging spectrometer with 400 km altitude, 0.4-1.0 microm wavelength range, 5 F-number of 720 mm focal length and 4.3 degrees total field was designed. Optical fiber was used to transfer the image in telescope's focal plane to three slits arranged in the same plane so as to achieve subfield. The CCD detector with 1 024 x 1 024 and 18 microm x 18 microm was used to receive the image of the three slits after dispersing. Using ZEMAX software optimization and tolerance analysis, the system can satisfy 5 nm spectrum resolution and 5 m field resolution, and the MTF is over 0.62 with 28 lp x mm(-1). The field of the system is almost 3 times that of similar instruments used in space probe.

The 2017 Plasma Roadmap: Low temperature plasma science and technology

NASA Astrophysics Data System (ADS)

Adamovich, I.; Baalrud, S. D.; Bogaerts, A.; Bruggeman, P. J.; Cappelli, M.; Colombo, V.; Czarnetzki, U.; Ebert, U.; Eden, J. G.; Favia, P.; Graves, D. B.; Hamaguchi, S.; Hieftje, G.; Hori, M.; Kaganovich, I. D.; Kortshagen, U.; Kushner, M. J.; Mason, N. J.; Mazouffre, S.; Mededovic Thagard, S.; Metelmann, H.-R.; Mizuno, A.; Moreau, E.; Murphy, A. B.; Niemira, B. A.; Oehrlein, G. S.; Petrovic, Z. Lj; Pitchford, L. C.; Pu, Y.-K.; Rauf, S.; Sakai, O.; Samukawa, S.; Starikovskaia, S.; Tennyson, J.; Terashima, K.; Turner, M. M.; van de Sanden, M. C. M.; Vardelle, A.

2017-08-01

Journal of Physics D: Applied Physics published the first Plasma Roadmap in 2012 consisting of the individual perspectives of 16 leading experts in the various sub-fields of low temperature plasma science and technology. The 2017 Plasma Roadmap is the first update of a planned series of periodic updates of the Plasma Roadmap. The continuously growing interdisciplinary nature of the low temperature plasma field and its equally broad range of applications are making it increasingly difficult to identify major challenges that encompass all of the many sub-fields and applications. This intellectual diversity is ultimately a strength of the field. The current state of the art for the 19 sub-fields addressed in this roadmap demonstrates the enviable track record of the low temperature plasma field in the development of plasmas as an enabling technology for a vast range of technologies that underpin our modern society. At the same time, the many important scientific and technological challenges shared in this roadmap show that the path forward is not only scientifically rich but has the potential to make wide and far reaching contributions to many societal challenges.

BOOK REVIEW: Solid State Physics: An Introduction

NASA Astrophysics Data System (ADS)

Jakoby, Bernhard

2009-07-01

There's a wealth of excellent textbooks on solid state physics. The author of the present book is well aware of this fact and does not attempt to write just another one. Rather, he has provided a very compact introduction to solid state physics for third-year students. As we are faced with the continuous appearance interdisciplinary fields and associated study curricula in natural and engineering sciences (biophysics, mechatronics, etc), a compact text in solid state physics would be appreciated by students of these disciplines as well. The book features 11 chapters where each is provided with supplementary discussion questions and problems. The first chapters deal with a review of chemical bonding mechanisms, crystal structures and mechanical properties of solids, which are brief but by no means superficial. The following, somewhat more detailed chapter on thermal properties of lattices includes a nice introduction to phonons. The foundations of solid state electronics are treated in the next three chapters. Here the author first discusses the classical treatment of electronic behaviour in metals (Drude model) and continues with a quantum-theoretical approach starting with the free-electron model and leading to the band structures in conductive solids. The next chapter is devoted to semiconductors and ends with a brief but, with respect to the topical scope, adequate discussion of semiconductor devices. The classical topics of magnetic and dielectric behaviour are treated in the sequel. The book closes with a chapter on superconductivity and a brief chapter covering the modern topics of quantum confinement and aspects of nanoscale physics. In my opinion, the author has succeeded in creating a very concise yet not superficial textbook. The account presented often probes subjects deep enough to lay the basis for a thorough understanding, preparing the reader for more specialized textbooks. For instance, I think that this book may serve as an excellent first introduction to semiconductor physics. Of course, the detailed treatment of some topics had to be spared and it is certainly a matter of taste which subjects should be treated in detail in a solid state textbook and which can be covered by references to other textbooks or further literature. A typical example for the latter is the decision to omit the detailed treatment of the local field concept leading to the Clausius-Mosotti relation. What could be improved in further editions (which will hopefully be coming) are more specific cross-references within the book and to other textbooks. In the current edition, missing internal cross-references can be compensated for by consulting the subject index, but it would be nicer to have these in the text. As mentioned above, I expect that this book will also be useful to engineering students. For these, it would be beneficial to provide more details on underlying terms and concepts that they, according to common engineering curricula, may not be that familiar with. Examples for such topics are quantum theory beyond the very first principles (e.g., multi-particle treatment, operators and observables) and thermodynamics (e.g., the relevance of electrochemical potential and Fermi levels). These topics could be treated in a concise manner in additional appendices. The current appendix is very short and rudimentary at times, e.g., for the microscopic form of Maxwell's equations, electric and magnetic fluxes are introduced but not outlined further (in that respect, it could also be useful to have a list of used symbols). In summary, this textbook definitely has an interesting scope within an established field and it has been written with appealing didactic skills. This first edition truly deserves to be discovered by students of various disciplines, who want to obtain a quick introduction to solid state physics.

Graphical representations of the chemistry of garnets in a three-dimensional MATLAB based provenance plot

NASA Astrophysics Data System (ADS)

Knierzinger, Wolfgang; Palzer, Markus; Wagreich, Michael; Meszar, Maria; Gier, Susanne

2016-04-01

A newly developed, MATLAB based garnet provenance plot allows a three-dimensional tetrahedral representation of the chemistry of garnets for the endmembers almandine, pyrope, spessartine and grossular. Based on a freely accessible database of Suggate & Hall (2013) and additional EPMA-data on the internet, the chemistry of more than 2500 garnets was evaluated and used to create various subfields that correspond to different facies conditions of metapelitic, metasomatic and metaigneous rocks as well as granitic rocks. These triangulated subfields act as reference structures within the tetrahedron, facilitating assignments of garnet chemistries to different lithologies. In comparison with conventional tenary garnet discrimination diagrams by Mange & Morton (2007), Wright/Preston et al. (1938/2002) and Aubrecht et al. (2009), this tetrahedral provenance plot enables a better assessment of the conditions of formation of garnets by reducing the overlapping of certain subfields. In particular, a clearer distinction between greenschist facies rocks, amphibolite facies rocks and granitic rocks can be achieved. First applications of the tetrahedral garnet plot provided new insights on sedimentary processes during the Lower Miocene in the pre-Alpine Molasse basin. Bibliography Aubrecht, R., Meres, S., Sykora, M., Mikus, T. (2009). Provenance of the detrital garnets and spinels from the Albian sediments of the Czorsztyn Unit (Pieniny Klippen Belt , Western Carpathians, Slovakia). In: Geologica Carpathica, Dec. 2009, 60, 6, pp. 463-483. Mange, M.A., Morton, A.C. (2007). Geochemistry of Heavy Minerals. In: Mange, M.A. & Wright, D.T.(2007).Heavy Minerals in Use, Amsterdam, pp. 345-391. Preston, J., Hartley, A., Mange-Rajetzky, M., Hole, M., May, G., Buck, S., Vaughan, L. (2002). The provenance of Triassic continental sandstones from the Beryl Field, northern North Sea: Mineralogical, geochemical and sedimentological constraints. In: Journal of Sedimentary Research, 72, pp. 18-29. Suggate, S.M., Hall, R., (2013). Using detrital garnet compositions to determine provenance: a new compositional database and procedure. In: Scott, R.A., Smyth, H.R., Morton, A.C., Richardson, N. (Eds.), Sediment Provenance Studies in Hydrocarbon Exploration and Production. Geological Society of London, Special Publication, 386. http://dx.doi.org/10.1144/SP386.8 Wright, W.I., (1938).The composition and occurrence of garnets. In: American Mineralogist, 23,pp. 436 - 449.

The Clinical Features of Paranoia in the 20th Century and Their Representation in Diagnostic Criteria From DSM-III Through DSM-5.

PubMed

Kendler, Kenneth S

2017-03-01

This review traces, through psychiatric textbooks, the history of the Kraepelinian concept of paranoia in the 20th century and then relates the common reported symptoms and signs to the diagnostic criteria for paranoia/delusional disorder in DSM-III through DSM-5. Clinical descriptions of paranoia appearing in 10 textbooks, published 1899 to 1970, revealed 11 prominent symptoms and signs reported by 5 or more authors. Three symptoms (systematized delusions, minimal hallucinations, and prominent ideas of reference) and 2 signs (chronic course and minimal affective deterioration) were reported by 8 or 9 of the authors. Four textbook authors rejected the Kraepelinian concept of paranoia. A weak relationship was seen between the frequency with which the clinical features were reported and the likelihood of their inclusion in modern DSM manuals. Indeed, the diagnostic criteria for paranoia/delusional disorder shifted substantially from DSM-III to DSM-5. The modern operationalized criteria for paranoia/delusional disorder do not well reflect the symptoms and signs frequently reported by historical experts. In contrast to results of similar reviews for depression, schizophrenia and mania, the clinical construct of paranoia/delusional disorder has been somewhat unstable in Western Psychiatry since the turn of the 20th century as reflected in both textbooks and the DSM editions. © The Author 2017. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Emergence of a scientific and commercial research and development infrastructure for human gene therapy.

PubMed

Crofts, Christine; Krimsky, Sheldon

2005-02-01

A research and clinical subfield known as "human gene therapy" has grown rapidly since 1990, when the first human trials were approved in the United States. Using quantitative data, this paper describes and analyzes the research and commercial infrastructure, including academic centers, publications, intellectual property, and biotechnology firms, that has developed around the goal of discovering clinical applications for the modification and transport of DNA to somatic cells. Despite setbacks and few documented successes, the subfield of human gene therapy continues to serve as an influential clinical paradigm for the treatment of inherited and noninherited diseases.

A bibliography of references to avian cholera

USGS Publications Warehouse

Wilson, Sonoma S.

1979-01-01

Mrs. Wilson has made a genuine effort to include in this bibliography every significant reference to avian cholera since Louis Pasteur's articles appeared in 1880, although she recognizes the likelihood that a few have been overlooked. New listings have been added throughout 1978, but comprehensive coverage of the literature cannot be claimed beyond June of that year.Textbook accounts, because they are generally summaries of work published elsewhere, are excluded. Papers dealing primarily with the biology of Pasteurella multocida, as opposed to the disease it induces in birds, are also excluded, unless they report information of diagnostic usefulness. Short abstracts are not included unless the journals in which they are published are more widely available than those in which the complete articles appear or they are English summaries of foreign language articles.In compiling this bibliography, Mrs. Wilson has made extensive use of Biological Abstracts, the Pesticide Documentation Bulletin, and printouts generated by Bibliographic Retrieval Services, Inc. The "Literature Cited" sections of textbooks and journal articles pertinent to the subject were sources of many additional references. Regardless of the origin of the citation, its accuracy was confirmed by comparison with the original publication, except in those few instances (marked with an asterisk) when the journal was not on the shelves of the libraries accessible to us.The author will be grateful to users of the bibliography who point out errors or omissions.Wayne I. JensenMicrobiologist In Charge

MYCIN II: design and implementation of a therapy reference with complex content-based indexing.

PubMed Central

Kim, D. K.; Fagan, L. M.; Jones, K. T.; Berrios, D. C.; Yu, V. L.

1998-01-01

We describe the construction of MYCIN II, a prototype system that provides for content-based markup and search of a forthcoming clinical therapeutics textbook, Antimicrobial Therapy and Vaccines. Existing commercial search technology for digital references utilizes generic tools such as textword-based searches with geographical or statistical refinements. We suggest that the drawbacks of such systems significantly restrict their use in everyday clinical practice. This is in spite of the fact that there is a great need for the information contained within these same references. The system we describe is intended to supplement keyword searching so that certain important questions can be asked easily and can be answered reliably (in terms of precision and recall). Our method attacks this problem in a restricted domain of knowledge-clinical infectious disease. For example, we would like to be able to answer the class of questions exemplified by the following query: "What antimicrobial agents can be used to treat endocarditis caused by Eikenella corrodens?" We have compiled and analyzed a list of such questions to develop a concept-based markup scheme. This scheme was then applied within an HTML markup to electronically "highlight" passages from three textbook chapters. We constructed a functioning web-based search interface. Our system also provides semi-automated querying of PubMed using our concept markup and the user's actions as a guide. PMID:9929205

MYCIN II: design and implementation of a therapy reference with complex content-based indexing.

PubMed

Kim, D K; Fagan, L M; Jones, K T; Berrios, D C; Yu, V L

1998-01-01

We describe the construction of MYCIN II, a prototype system that provides for content-based markup and search of a forthcoming clinical therapeutics textbook, Antimicrobial Therapy and Vaccines. Existing commercial search technology for digital references utilizes generic tools such as textword-based searches with geographical or statistical refinements. We suggest that the drawbacks of such systems significantly restrict their use in everyday clinical practice. This is in spite of the fact that there is a great need for the information contained within these same references. The system we describe is intended to supplement keyword searching so that certain important questions can be asked easily and can be answered reliably (in terms of precision and recall). Our method attacks this problem in a restricted domain of knowledge-clinical infectious disease. For example, we would like to be able to answer the class of questions exemplified by the following query: "What antimicrobial agents can be used to treat endocarditis caused by Eikenella corrodens?" We have compiled and analyzed a list of such questions to develop a concept-based markup scheme. This scheme was then applied within an HTML markup to electronically "highlight" passages from three textbook chapters. We constructed a functioning web-based search interface. Our system also provides semi-automated querying of PubMed using our concept markup and the user's actions as a guide.

Teach Astronomy: An Online Resource for Introductory Astronomy Courses and Informal Learners

NASA Astrophysics Data System (ADS)

Austin, Carmen; Impey, C. D.; Hardegree-Ullman, K.; Patikkal, A.; Ganesan, N.

2013-01-01

Teach Astronomy (www.teachastronomy.com) is a new, free online resource—a teaching tool for non-science major astronomy courses and a reference guide for lifelong learners interested in the subject. Digital content available includes: a comprehensive introductory astronomy textbook by Chris Impey, Wikipedia astronomy articles, images from Astronomy Picture of the Day archives and AstroPix database, two to three minute topical video clips by Chris Impey, podcasts from 365 Days of Astronomy archives, and an RSS feed of astronomy news from Science Daily. Teach Astronomy features an original technology called the Wikimap to cluster, display, and navigate site search results. Motivation behind the development of Teach Astronomy includes steep increases in textbook prices, the rapid adoption by students and the public of digital resources, and the modern capabilities of digital technology. Recent additions to Teach Astronomy include: AstroPix images—from some of the most advanced observatories and complete with metadata, mobile device functionality, links to WikiSky where users can see the location of astronomical objects in the sky, and end of chapter textbook review questions. Next in line for development are assignments for classroom use. We present suggestions for utilizing the rich content and features of the web site.

Genetic engineering: a matter that requires further refinement in Spanish secondary school textbooks

NASA Astrophysics Data System (ADS)

Martínez-Gracia, M. V.; Gil-Quýlez, M. J.

2003-09-01

Genetic engineering is now an integral part of many high school textbooks but little work has been done to assess whether it is being properly addressed. A checklist with 19 items was used to analyze how genetic engineering is presented in biology textbooks commonly used in Spanish high schools, including the content, its relationship with fundamental genetic principles, and how it aims to improve the genetic literacy of students. The results show that genetic engineering was normally introduced without a clear reference to the universal genetic code, protein expression or the genetic material shared by all species. In most cases it was poorly defined, without a clear explanation of all the relevant processes involved. Some procedures (such as vectors) were explained in detail without considering previous student knowledge or skills. Some books emphasized applications such as the human genome project without describing DNA sequencing. All books included possible repercussions, but in most cases only fashionable topics such as human cloning. There was an excess of information that was not always well founded and hence was unsuitable to provide a meaningful understanding of DNA technology required for citizens in the twenty-first century.

COOPER, HERON, AND HEWARD'S APPLIED BEHAVIOR ANALYSIS (2ND ED.): CHECKERED FLAG FOR STUDENTS AND PROFESSORS, YELLOW FLAG FOR THE FIELD

PubMed Central

Friman, Patrick C

2010-01-01

At last, the field of applied behavior analysis has a beautifully crafted, true textbook that can proudly stand cover to cover and spine to spine beside any of the expensive, imposing, and ornately designed textbooks used by college instructors who teach courses in conventional areas of education or psychology. In this review, I fully laud this development, credit Cooper, Heron, and Heward for making it happen, argue that it signifies a checkered flag for students and professors, and recommend the book for classes in applied behavior analysis everywhere. Subsequently, I review its chapters, each of which could easily stand alone as publications in their own right. Finally, I supply a cautionary note, a yellow flag to accompany the well-earned checkered flag, by pointing out that, as is true with all general textbooks on applied behavior analysis, a major portion of the references involves research on persons who occupy only a tail of the normal distribution. To attain the mainstream role Skinner envisioned and most (if not all) behavior analysts desire, the field will have to increase its focus on persons who reside under the dome of that distribution.

Usability of PDF based Digital Textbooks to the Physically Disabled University Student.

PubMed

Oku, Hidehisa; Matsubara, Kayoko; Booka, Masayuki

2015-01-01

Digital textbooks have been expected for providing multimedia information that the print textbooks could not handle. The original digital textbook can be fabricated relatively easily by using Epub or DAISY. Print textbooks are, however, employed as textbooks in the most of lectures in universities. Therefore, it is considered necessary to convert the content of the print textbook to the digital textbook simply and in a short time. In this paper, the digital textbook using PDF files of the print textbook was suggested as one of simple and practical solution to provide an alternative textbook for the physically disabled university student who has difficulty handling the print textbook. Then usability of the suggested method was evaluated experimentally from the point of workload. Result of the experiment indicates that the digital textbook fabricated as the alternative one for the print textbook by the suggested method has a potential to reduce workload for the physically disabled university students. In addition, the digital textbook with larger LCD display needs less workload than the print textbook. Then, there are not so much difference in the workload between the print book which is smaller than the print textbook and the digital book made from the print book.

A New Look at Contextualization and Application: A Comprehensive Pedagogical Strategy for Business German.

ERIC Educational Resources Information Center

Strack, Thomas; Clausing, Gerhard

This paper discusses the problems faced by teachers of business German, the possible goals of business German courses, and the design of an effective textbook to integrate business content and language skills. Special reference is made to the two-semester business German course offered by the University of Southern California (USC). The major goal…

Need an Upgrade from "Once Upon a Time..."? Try This Storybook

ERIC Educational Resources Information Center

Coffman, Margaret; Eidietis, Laura; Gardiner, Lisa; Hatheway, Becca; Henderson, Sandra; Rutherford, Sandra

2009-01-01

"Ducks in the Flow, Where Did They Go?" represents a fusion of language, arts and science. Offering both a story of discovery and factual science content, this hybrid storybook/textbook promotes literacy on several fronts: ocean principles, general science, and language/arts. A step up from the average text or reference book, "Ducks in the Flow"…

Mass, Energy, Entropy and Exergy Rate Balance in a Ranque-Hilsh Vortex Tube

ERIC Educational Resources Information Center

Carrascal Lecumberri, Edorta; Sala Lizarraga, José María

2013-01-01

The objective of this paper is to present a laboratory program designed for the Thermodynamics course offered in the Department of Thermal Engineering at the University of the Basque Country. With reference to one of the examples given in the textbook by Moran, Shapiro, Boettner and Bailey (2012), the balances of mass, energy, entropy and exergy…

Teaching English or Producing Docility? Foucauldian Analysis of Pakistani State-Mandated English Textbooks

ERIC Educational Resources Information Center

Channa, Liaquat Ali; Gilhooly, Daniel; Channa, Abdul Razaque; Manan, Syed Abdul

2017-01-01

The scholarship of language education, particularly with reference to learning and use of English, is marked by varieties of English. One may note two broad models: (1) ENL, ESL, and EFL; (2) EIL, ELF, and WEs. Although the scholarship is replete with debates, the debates seem to only construct and maintain that learning English and its use are…

Teaching the Role of the Indian in American History and Upgrading Curricula. A Position Paper.

ERIC Educational Resources Information Center

Costo, Rupert

Presented in this document is a discussion of the need for an ongoing evaluation of the accuracy and adequacy of materials pertaining to American Indians in textbooks and reference books in use, or being produced for use, in the nation's schools. During this ongoing evaluation, to be done by a recognized permanent national committee of Indian…

CAD/CAM (Computer Aided Design/Computer Aided Manufacture). A Brief Guide to Materials in the Library of Congress.

ERIC Educational Resources Information Center

Havas, George D.

This brief guide to materials in the Library of Congress (LC) on computer aided design and/or computer aided manufacturing lists reference materials and other information sources under 13 headings: (1) brief introductions; (2) LC subject headings used for such materials; (3) textbooks; (4) additional titles; (5) glossaries and handbooks; (6)…

Online Teaching in K-12: Models, Methods, and Best Practices for Teachers and Administrators

ERIC Educational Resources Information Center

Bryans-Bongey, Sarah, Ed.; Graziano, Kevin J., Ed.

2016-01-01

"Online Teaching in K-12" is the essential hands-on reference and textbook for education professionals seeking success in the planning, design, and teaching of K-12 online courses and programs. This skillfully edited book brings together more than two dozen experts and practitioners to present an array of innovative models and methods,…

Frederick Douglass and I: Writing to Read and Relate History with Life among African American Adolescents at a High-Poverty Urban School

ERIC Educational Resources Information Center

Morphy, Paul

2013-01-01

Purpose: Black history as represented in social studies textbooks often lacks depth demanded by historians and authenticity required for cultural relevance to African American students. However, important Black historical narratives sometimes contain difficult prose and refer to times or circumstances that are far removed from students' life…

Quantitative Comparison of 21 Protocols for Labeling Hippocampal Subfields and Parahippocampal Subregions in In Vivo MRI: Towards a Harmonized Segmentation Protocol

PubMed Central

Yushkevich, Paul A.; Amaral, Robert S. C.; Augustinack, Jean C.; Bender, Andrew R.; Bernstein, Jeffrey D.; Boccardi, Marina; Bocchetta, Martina; Burggren, Alison C.; Carr, Valerie A.; Chakravarty, M. Mallar; Chetelat, Gael; Daugherty, Ana M.; Davachi, Lila; Ding, Song-Lin; Ekstrom, Arne; Geerlings, Mirjam I.; Hassan, Abdul; Huang, Yushan; Iglesias, Eugenio; La Joie, Renaud; Kerchner, Geoffrey A.; LaRocque, Karen F.; Libby, Laura A.; Malykhin, Nikolai; Mueller, Susanne G.; Olsen, Rosanna K.; Palombo, Daniela J.; Parekh, Mansi B; Pluta, John B.; Preston, Alison R.; Pruessner, Jens C.; Ranganath, Charan; Raz, Naftali; Schlichting, Margaret L.; Schoemaker, Dorothee; Singh, Sachi; Stark, Craig E. L.; Suthana, Nanthia; Tompary, Alexa; Turowski, Marta M.; Van Leemput, Koen; Wagner, Anthony D.; Wang, Lei; Winterburn, Julie L.; Wisse, Laura E.M.; Yassa, Michael A.; Zeineh, Michael M.

2015-01-01

OBJECTIVE An increasing number of human in vivo magnetic resonance imaging (MRI) studies have focused on examining the structure and function of the subfields of the hippocampal formation (the dentate gyrus, CA fields 1–3, and the subiculum) and subregions of the parahippocampal gyrus (entorhinal, perirhinal, and parahippocampal cortices). The ability to interpret the results of such studies and to relate them to each other would be improved if a common standard existed for labeling hippocampal subfields and parahippocampal subregions. Currently, research groups label different subsets of structures and use different rules, landmarks, and cues to define their anatomical extents. This paper characterizes, both qualitatively and quantitatively, the variability in the existing manual segmentation protocols for labeling hippocampal and parahippocampal substructures in MRI, with the goal of guiding subsequent work on developing a harmonized substructure segmentation protocol. METHOD MRI scans of a single healthy adult human subject were acquired both at 3 Tesla and 7 Tesla. Representatives from 21 research groups applied their respective manual segmentation protocols to the MRI modalities of their choice. The resulting set of 21 segmentations was analyzed in a common anatomical space to quantify similarity and identify areas of agreement. RESULTS The differences between the 21 protocols include the region within which segmentation is performed, the set of anatomical labels used, and the extents of specific anatomical labels. The greatest overall disagreement among the protocols is at the CA1/subiculum boundary, and disagreement across all structures is greatest in the anterior portion of the hippocampal formation relative to the body and tail. CONCLUSIONS The combined examination of the 21 protocols in the same dataset suggests possible strategies towards developing a harmonized subfield segmentation protocol and facilitates comparison between published studies. PMID:25596463

Highlights in bioethics through 40 years: a quantitative analysis of top-cited journal articles.

PubMed

Jin, Pingyue; Hakkarinen, Mark

2017-05-01

The field of bioethics is constantly evolving. To investigate trends in the field of bioethics, we conducted a quantitative analysis of the top-cited articles in bioethical journals over the past 40 years. Retrospective quantitative study of the 20 most cited bioethics articles published each year from 1975 to 2014 were conducted. Article samples were selected from a list of the most relevant 100 journals in the field of bioethics. In total, 800 top-cited articles between 1975 and 2014 in the domain of bioethics were retrieved and analysed. More than half of them were composed by single authors, but multiauthorship became more prevalent with time. The majority (84.5%) of these highly cited articles originated from the USA (65.3%), UK or Canada, though the proportion of other countries increased in recent years. Almost half (44.6%) of the highly cited articles belonged to the subfield of clinical ethics , but other subfields such as research ethics , public health ethics and neuroethics became more prominent. Overall, the distribution of Thesaurus keywords and subfields became more diverse over time, and the number of journals publishing top-cited articles doubled. Furthermore, the empirical ethics approach increased over time in our sample of top-cited articles. In sum, the forefront of bioethics is getting more diversified, collaborative and international. The presumed 'mainstream' becomes less dominant over time, as more highly cited articles come from new subfields, discuss new topics, use more Bioethics Thesaurus keywords, more authors participate and more countries other than the USA contribute to bioethics journals. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

Protective Effects of 17β-Estradiol on Hippocampal Myelinated Fibers in Ovariectomized Middle-aged Rats.

PubMed

Xiao, Qian; Luo, Yanmin; Lv, Fulin; He, Qi; Wu, Hong; Chao, Fenglei; Qiu, Xuan; Zhang, Lei; Gao, Yuan; Huang, Chunxia; Wang, Sanrong; Zhou, Chunni; Zhang, Yi; Jiang, Lin; Tang, Yong

2018-06-14

Estrogen replacement therapy (ERT) improves hippocampus-dependent cognition. This study investigated the impact of estrogen on hippocampal volume, CA1 subfield volume and myelinated fibers in the CA1 subfield of middle-aged ovariectomized rats. Ten-month-old bilaterally ovariectomized (OVX) female rats were randomly divided into OVX + E2 and OVX + Veh groups. After four weeks of subcutaneous injection with 17β-estradiol or a placebo, the OVX + E2 rats exhibited significantly short mean escape latency in a spatial learning task than that in the OVX + Veh rats. Using stereological methods, we did not observe significant differences in the volumes of the hippocampus and CA1 subfields between the two groups. However, using stereological methods and electron microscopy techniques, the total length of myelinated fibers and the total volumes of myelinated fibers, myelin sheaths and myelinated axons in the CA1 subfields of OVX + E2 rats were significantly 38.1%, 34.2%, 36.1% and 32.5%, respectively, higher than those in the OVX + Veh rats. After the parameters were calculated according to different diameter ranges, the estrogen replacement-induced remodeling of myelinated fibers in CA1 was mainly manifested in the myelinated fibers with a diameter of <1.0 μm. Therefore, four weeks of continuous E2 replacement improved the spatial learning capabilities of middle-aged ovariectomized rats. The E2 replacement-induced protection of spatial learning abilities might be associated with the beneficial effects of estrogen on myelinated fibers, particularly those with the diameters less than 1.0 μm, in the hippocampal CA1 region of middle-aged ovariectomized rats. Copyright © 2018 IBRO. Published by Elsevier Ltd. All rights reserved.

Optical Coherence Tomography Minimum Intensity as an Objective Measure for the Detection of Hydroxychloroquine Toxicity.

PubMed

Allahdina, Ali M; Stetson, Paul F; Vitale, Susan; Wong, Wai T; Chew, Emily Y; Ferris, Fredrick L; Sieving, Paul A; Cukras, Catherine

2018-04-01

As optical coherence tomography (OCT) minimum intensity (MI) analysis provides a quantitative assessment of changes in the outer nuclear layer (ONL), we evaluated the ability of OCT-MI analysis to detect hydroxychloroquine toxicity. Fifty-seven predominantly female participants (91.2% female; mean age, 55.7 ± 10.4 years; mean time on hydroxychloroquine, 15.0 ± 7.5 years) were enrolled in a case-control study and categorized into affected (i.e., with toxicity, n = 19) and unaffected (n = 38) groups using objective multifocal electroretinographic (mfERG) criteria. Spectral-domain OCT scans of the macula were analyzed and OCT-MI values quantitated for each subfield of the Early Treatment Diabetic Retinopathy Study (ETDRS) grid. A two-sample U-test and a cross-validation approach were used to assess the sensitivity and specificity of toxicity detection according to OCT-MI criteria. The medians of the OCT-MI values in all nine of the ETDRS subfields were significantly elevated in the affected group relative to the unaffected group (P < 0.005 for all comparisons), with the largest difference found for the inner inferior subfield (P < 0.0001). The receiver operating characteristic analysis of median MI values of the inner inferior subfields showed high sensitivity and high specificity in the detection of toxicity with area under the curve = 0.99. Retinal changes secondary to hydroxychloroquine toxicity result in increased OCT reflectivity in the ONL that can be detected and quantitated using OCT-MI analysis. Analysis of OCT-MI values demonstrates high sensitivity and specificity for detecting the presence of hydroxychloroquine toxicity in this cohort and may contribute additionally to current screening practices.

Optical Coherence Tomography Minimum Intensity as an Objective Measure for the Detection of Hydroxychloroquine Toxicity

PubMed Central

Allahdina, Ali M.; Stetson, Paul F.; Vitale, Susan; Wong, Wai T.; Chew, Emily Y.; Ferris, Fredrick L.; Sieving, Paul A.

2018-01-01

Purpose As optical coherence tomography (OCT) minimum intensity (MI) analysis provides a quantitative assessment of changes in the outer nuclear layer (ONL), we evaluated the ability of OCT-MI analysis to detect hydroxychloroquine toxicity. Methods Fifty-seven predominantly female participants (91.2% female; mean age, 55.7 ± 10.4 years; mean time on hydroxychloroquine, 15.0 ± 7.5 years) were enrolled in a case-control study and categorized into affected (i.e., with toxicity, n = 19) and unaffected (n = 38) groups using objective multifocal electroretinographic (mfERG) criteria. Spectral-domain OCT scans of the macula were analyzed and OCT-MI values quantitated for each subfield of the Early Treatment Diabetic Retinopathy Study (ETDRS) grid. A two-sample U-test and a cross-validation approach were used to assess the sensitivity and specificity of toxicity detection according to OCT-MI criteria. Results The medians of the OCT-MI values in all nine of the ETDRS subfields were significantly elevated in the affected group relative to the unaffected group (P < 0.005 for all comparisons), with the largest difference found for the inner inferior subfield (P < 0.0001). The receiver operating characteristic analysis of median MI values of the inner inferior subfields showed high sensitivity and high specificity in the detection of toxicity with area under the curve = 0.99. Conclusions Retinal changes secondary to hydroxychloroquine toxicity result in increased OCT reflectivity in the ONL that can be detected and quantitated using OCT-MI analysis. Analysis of OCT-MI values demonstrates high sensitivity and specificity for detecting the presence of hydroxychloroquine toxicity in this cohort and may contribute additionally to current screening practices. PMID:29677357

Memory performance, global cerebral volumes and hippocampal subfield volumes in long-term survivors of Out-of-Hospital Cardiac Arrest.

PubMed

Ørbo, Marte C; Vangberg, Torgil R; Tande, Pål M; Anke, Audny; Aslaksen, Per M

2018-05-01

We explored the associations between global brain volumes, hippocampal subfield volumes and verbal memory performance in long-term survivors of out-of-hospital cardiac arrest (OHCA). Three months after OHCA, survivors and healthy, age-matched controls were assessed with cerebral MRI and the California Verbal Learning Test-II (CVLT-II). Volumetric brain segmentation was performed automatically by FreeSurfer. Twenty-six OHCA survivors who were living independently in regular homes at the time of assessment and 19 controls participated in the study. Thirteen of the survivors had been conscious upon arrival to the emergency department. The other 13 survivors had 0.5-7 days of inpatient coma before recovery. Memory was poorer in the OHCA group that had been comatose beyond initial hospital admission compared to both other groups. Total cortical volumes, total hippocampus volumes and several hippocampal subfield volumes were significantly smaller in the OHCA group comatose beyond initial hospital admission compared to controls. No significant differences between the OHCA group conscious upon emergency department arrival and the other two groups were found for brain volumes. No significant differences were observed between any groups for white matter or total subcortical volumes. In OHCA survivors with recovery from inpatient coma, the various CVLT-II trials were significantly, but differentially, correlated to total gray matter volume, cortical volume and the hippocampal subfield subiculum. In this small, single-site study, both hippocampal volume and cortical volume were smaller in good outcome OHCA survivors 3 months after resuscitation in comparison to healthy controls. Smaller cerebral volumes were correlated with poorer memory performance. Copyright © 2018 Elsevier B.V. All rights reserved.

In vivo imaging of prodromal hippocampus CA1 subfield oxidative stress in models of Alzheimer disease and Angelman syndrome.

PubMed

Berkowitz, Bruce A; Lenning, Jacob; Khetarpal, Nikita; Tran, Catherine; Wu, Johnny Y; Berri, Ali M; Dernay, Kristin; Haacke, E Mark; Shafie-Khorassani, Fatema; Podolsky, Robert H; Gant, John C; Maimaiti, Shaniya; Thibault, Olivier; Murphy, Geoffrey G; Bennett, Brian M; Roberts, Robin

2017-09-01

Hippocampus oxidative stress is considered pathogenic in neurodegenerative diseases, such as Alzheimer disease (AD), and in neurodevelopmental disorders, such as Angelman syndrome (AS). Yet clinical benefits of antioxidant treatment for these diseases remain unclear because conventional imaging methods are unable to guide management of therapies in specific hippocampus subfields in vivo that underlie abnormal behavior. Excessive production of paramagnetic free radicals in nonhippocampus brain tissue can be measured in vivo as a greater-than-normal 1/ T 1 that is quenchable with antioxidant as measured by quench-assisted (Quest) MRI. Here, we further test this approach in phantoms, and we present proof-of-concept data in models of AD-like and AS hippocampus oxidative stress that also exhibit impaired spatial learning and memory. AD-like models showed an abnormal gradient along the CA1 dorsal-ventral axis of excessive free radical production as measured by Quest MRI, and redox-sensitive calcium dysregulation as measured by manganese-enhanced MRI and electrophysiology. In the AS model, abnormally high free radical levels were observed in dorsal and ventral CA1. Quest MRI is a promising in vivo paradigm for bridging brain subfield oxidative stress and behavior in animal models and in human patients to better manage antioxidant therapy in devastating neurodegenerative and neurodevelopmental diseases.-Berkowitz, B. A., Lenning, J., Khetarpal, N., Tran, C., Wu, J. Y., Berri, A. M., Dernay, K., Haacke, E. M., Shafie-Khorassani, F., Podolsky, R. H., Gant, J. C., Maimaiti, S., Thibault, O., Murphy, G. G., Bennett, B. M., Roberts, R. In vivo imaging of prodromal hippocampus CA1 subfield oxidative stress in models of Alzheimer disease and Angelman syndrome. © FASEB.

Effects of undernourishment, recurrent seizures and enriched environment during early life in hippocampal morphology.

PubMed

Alvarez, Paula Steffen; Simão, Fabrício; Hemb, Marta; Xavier, Léder Leal; Nunes, Magda Lahorgue

2014-04-01

It has been recently shown that enriched environment led to a significant benefit in learning and retention of visual-spatial memory, being able to reverse the cognitive impairment generated by undernourishment and recurrent seizures. We investigated the hippocampal morphological effects of recurrent seizures and undernourishment early in life in Wistar rats and the possible benefits produced by the enriched environment in these conditions. The morphological parameters stereologically evaluated were hippocampal volume, thickness of pyramidal stratum of the CA1 subfield and neuronal and glial densities in the same subfield. Male Wistar rats were divided into eight groups including nourished, nourished+enriched environment, nourished+recurrent seizures, nourished+recurrent seizures+enriched environment, undernourished, undernourished+enriched environment, undernourished+recurrent seizures and undernourished+recurrent seizures+enriched environment. Undernourishment model consisted in nutritional deprivation regimen from post-natal day 2 (P2) to P15. From P8 to P10, recurrent seizures group were induced by flurothyl three times per day. Enriched environment groups were exposed between P21 and P51. Our main findings were: (1) animals submitted to the enriched environment showed an increased hippocampal volume; (2) enriched environment promotes increases in the thickness of the pyramidal layer in hippocampal CA1 subfield in animals nourished and undernourished with recurrent seizures; (3) undernourishment during early development decreased neuronal density in CA1 and CA3 subfields. Our findings show that these three conditions induces important changes in hippocampal morphology, the most deleterious changes are induced by undernourishment and recurrent seizures, while more beneficial morphological changes are produced by enriched environment. Copyright © 2014 ISDN. Published by Elsevier Ltd. All rights reserved.

Attitudes of health science students towards teaching practices, examinations, and other related issues.

PubMed

Shephard, R J; Ashley, M J

1979-03-01

A brief multiple choice questionnaire explored the attitudes of students enrolled in several health science faculties (medicine, pharmacy, nursing, and physical and health education). A substantial proportion indicated a wish for more challenging lectures. On the other hand, the majority of students devoted less than one hour of personal study per week to required 'courses', interest in health-related 'courses' being particularly weak. Small textbooks with minimal references were desired, and relatively little use was made of free lecture handouts. Financial constraints had little influence on personal study, but affected textbook purchase. The demand for 'handouts' would have been reduced by a charge. Frequent term examinations as a stimulus to learning were favoured by all groups, as were full or challenging presentations by instructors. Team teaching, although favoured generally, was not equally appealing to all groups.

Alfred Werner's role in the mid-20th century flourishing of American inorganic chemistry.

PubMed

Labinger, Jay A

2014-01-01

The development of organic and physical chemistry as specialist fields, during the middle and end of the 19th century respectively, left inorganic behind as a decidedly less highly regarded subfield of chemistry. Despite Alfred Werner's groundbreaking studies of coordination chemistry in the early 20th century, that inferior status remained in place - particularly in the US - until the 1950s, when the beginnings of a resurgence that eventually restored its parity with the other subfields can be clearly observed. This paper explores the extent to which Werner's heritage - both direct, in the form of academic descendants, and indirect - contributed to those advances.

Neurolinguistic measures of typological effects in multilingual transfer: introducing an ERP methodology

PubMed Central

Rothman, Jason; Alemán Bañón, José; González Alonso, Jorge

2015-01-01

This article has two main objectives. First, we offer an introduction to the subfield of generative third language (L3) acquisition. Concerned primarily with modeling initial stages transfer of morphosyntax, one goal of this program is to show how initial stages L3 data make significant contributions toward a better understanding of how the mind represents language and how (cognitive) economy constrains acquisition processes more generally. Our second objective is to argue for and demonstrate how this subfield will benefit from a neuro/psycholinguistic methodological approach, such as event-related potential experiments, to complement the claims currently made on the basis of exclusively behavioral experiments. PMID:26300800

The 2017 Plasma Roadmap: Low temperature plasma science and technology

DOE PAGES

Adamovich, I.; Baalrud, S. D.; Bogaerts, A.; ...

2017-07-14

Journal of Physics D: Applied Physics published the first Plasma Roadmap in 2012 consisting of the individual perspectives of 16 leading experts in the various sub-fields of low temperature plasma science and technology. The 2017 Plasma Roadmap is the first update of a planned series of periodic updates of the Plasma Roadmap. The continuously growing interdisciplinary nature of the low temperature plasma field and its equally broad range of applications are making it increasingly difficult to identify major challenges that encompass all of the many sub-fields and applications. This intellectual diversity is ultimately a strength of the field. The currentmore » state of the art for the 19 sub-fields addressed in this roadmap demonstrates the enviable track record of the low temperature plasma field in the development of plasmas as an enabling technology for a vast range of technologies that underpin our modern society. At the same time, the many important scientific and technological challenges shared in this roadmap show that the path forward is not only scientifically rich but has the potential to make wide and far reaching contributions to many societal challenges.« less

Physics education research: A research subfield of physics with gender parity

NASA Astrophysics Data System (ADS)

Barthelemy, Ramón S.; Van Dusen, Ben; Henderson, Charles

2015-12-01

Women currently outnumber men in obtaining undergraduate degrees but are underrepresented within STEM fields. However, women's representation varies by STEM field, and even further by STEM subfield. One field that has held a persistent low representation of women is physics. This paper seeks to uncover the truth behind an anecdotal claim that the subfield of physics education research (PER) has a higher representation of women than physics as a whole. Graduate students in PER completed an online survey to assess their demographics, trajectory in PER, climate experiences, and goals for their research. The response rate for the survey was 68%, yielding 125 total respondents. This paper will focus on the 91 respondents enrolled in U.S. graduate programs. It was found that women make up 51% of the U.S. PER graduate students in this sample, as compared to only 19% of physics graduate students overall. Survey findings also revealed that both women and men in PER graduate programs experience similarly positive working relationships with faculty and fellow students. Last, both men and women reported building a stronger scientific workforce and becoming better teachers as goals for their PER research.

Hippocampal CA3-dentate gyrus volume uniquely linked to improvement in associative memory from childhood to adulthood.

PubMed

Daugherty, Ana M; Flinn, Robert; Ofen, Noa

2017-06-01

Associative memory develops into adulthood and critically depends on the hippocampus. The hippocampus is a complex structure composed of subfields that are functionally-distinct, and anterior-posterior divisions along the length of the hippocampal horizontal axis that may also differ by cognitive correlates. Although each of these aspects has been considered independently, here we evaluate their relative contributions as correlates of age-related improvement in memory. Volumes of hippocampal subfields (subiculum, CA1-2, CA3-dentate gyrus) and anterior-posterior divisions (hippocampal head, body, tail) were manually segmented from high-resolution images in a sample of healthy participants (age 8-25 years). Adults had smaller CA3-dentate gyrus volume as compared to children, which accounted for 67% of the indirect effect of age predicting better associative memory via hippocampal volumes. Whereas hippocampal body volume demonstrated non-linear age differences, larger hippocampal body volume was weakly related to better associative memory only when accounting for the mutual correlation with subfields measured within that region. Thus, typical development of associative memory was largely explained by age-related differences in CA3-dentate gyrus. Copyright © 2017 Elsevier Inc. All rights reserved.

Hippocampal maturity promotes memory distinctiveness in childhood and adolescence

PubMed Central

Keresztes, Attila; Bender, Andrew R.; Bodammer, Nils C.; Shing, Yee Lee

2017-01-01

Adaptive learning systems need to meet two complementary and partially conflicting goals: detecting regularities in the world versus remembering specific events. The hippocampus (HC) keeps a fine balance between computations that extract commonalities of incoming information (i.e., pattern completion) and computations that enable encoding of highly similar events into unique representations (i.e., pattern separation). Histological evidence from young rhesus monkeys suggests that HC development is characterized by the differential development of intrahippocampal subfields and associated networks. However, due to challenges in the in vivo investigation of such developmental organization, the ontogenetic timing of HC subfield maturation remains controversial. Delineating its course is important, as it directly influences the fine balance between pattern separation and pattern completion operations and, thus, developmental changes in learning and memory. Here, we relate in vivo, high-resolution structural magnetic resonance imaging data of HC subfields to behavioral memory performance in children aged 6–14 y and in young adults. We identify a multivariate profile of age-related differences in intrahippocampal structures and show that HC maturity as captured by this pattern is associated with age differences in the differential encoding of unique memory representations. PMID:28784801

Hippocampal CA3-dentate gyrus volume uniquely linked to improvement in associative memory from childhood to adulthood

PubMed Central

Daugherty, Ana M.; Flinn, Robert; Ofen, Noa

2017-01-01

Associative memory develops into adulthood and critically depends on the hippocampus. The hippocampus is a complex structure composed of subfields that are functionally-distinct, and anterior-posterior divisions along the length of the hippocampal horizontal axis that may also differ by cognitive correlates. Although each of these aspects has been considered independently, here we evaluate their relative contributions as correlates of age-related improvement in memory. Volumes of hippocampal subfields (subiculum, CA1-2, CA3-dentate gyrus) and anterior-posterior divisions (hippocampal head, body, tail) were manually segmented from high-resolution proton density-weighted images in a sample of healthy participants (age 8–25 years). Adults had smaller CA3-dentate gyrus volume as compared to children, which accounted for 67% of the indirect effect of age predicting better associative memory via hippocampal volumes. Whereas hippocampal body volume demonstrated non-linear age differences, larger hippocampal body volume was weakly related to better associative memory only when accounting for the mutual correlation with subfields measured within that region. Thus, typical development of associative memory was largely explained by age-related differences in CA3-dentate gyrus. PMID:28342999

The 2017 Plasma Roadmap: Low temperature plasma science and technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adamovich, I.; Baalrud, S. D.; Bogaerts, A.

Journal of Physics D: Applied Physics published the first Plasma Roadmap in 2012 consisting of the individual perspectives of 16 leading experts in the various sub-fields of low temperature plasma science and technology. The 2017 Plasma Roadmap is the first update of a planned series of periodic updates of the Plasma Roadmap. The continuously growing interdisciplinary nature of the low temperature plasma field and its equally broad range of applications are making it increasingly difficult to identify major challenges that encompass all of the many sub-fields and applications. This intellectual diversity is ultimately a strength of the field. The currentmore » state of the art for the 19 sub-fields addressed in this roadmap demonstrates the enviable track record of the low temperature plasma field in the development of plasmas as an enabling technology for a vast range of technologies that underpin our modern society. At the same time, the many important scientific and technological challenges shared in this roadmap show that the path forward is not only scientifically rich but has the potential to make wide and far reaching contributions to many societal challenges.« less

Technology and Textbooks: The Future

ERIC Educational Resources Information Center

Baglione, Stephen L.; Sullivan, Kevin

2016-01-01

This article describes two separate studies: a survey of students' textbook perceptions, purchases, and usage for e-textbooks and print textbooks and a conjoint analysis on e-textbook attributes. Print textbooks were perceived as easier to read, understand, and navigate, whereas e-textbooks were perceived to be cheaper. Students were willing to…

Undisclosed conflicts of interest among biomedical textbook authors.

PubMed

Piper, Brian J; Lambert, Drew A; Keefe, Ryan C; Smukler, Phoebe U; Selemon, Nicolas A; Duperry, Zachary R

2018-02-05

Textbooks are a formative resource for health care providers during their education and are also an enduring reference for pathophysiology and treatment. Unlike the primary literature and clinical guidelines, biomedical textbook authors do not typically disclose potential financial conflicts of interest (pCoIs). The objective of this study was to evaluate whether the authors of textbooks used in the training of physicians, pharmacists, and dentists had appreciable undisclosed pCoIs in the form of patents or compensation received from pharmaceutical or biotechnology companies. The most recent editions of six medical textbooks, Harrison's Principles of Internal Medicine ( Har PIM), Katzung and Trevor's Basic and Clinical Pharmacology ( Kat BCP), the American Osteopathic Association's Foundations of Osteopathic Medicine ( AOA FOM), Remington: The Science and Practice of Pharmacy ( Rem SPP), Koda-Kimble and Young's Applied Therapeutics ( KKY AT), and Yagiela's Pharmacology and Therapeutics for Dentistry ( Yag PTD), were selected after consulting biomedical educators for evaluation. Author names (N = 1,152, 29.2% female) were submitted to databases to examine patents (Google Scholar) and compensation (ProPublica's Dollars for Docs [PDD]). Authors were listed as inventors on 677 patents (maximum/author = 23), with three-quarters (74.9%) to Har PIM authors. Females were significantly underrepresented among patent holders. The PDD 2009-2013 database revealed receipt of US$13.2 million, the majority to (83.9%) to Har PIM. The maximum compensation per author was $869,413. The PDD 2014 database identified receipt of $6.8 million, with 50.4% of eligible authors receiving compensation. The maximum compensation received by a single author was $560,021. Cardiovascular authors were most likely to have a PDD entry and neurologic disorders authors were least likely. An appreciable subset of biomedical authors have patents and have received remuneration from medical product companies and this information is not disclosed to readers. These findings indicate that full transparency of financial pCoI should become a standard practice among the authors of biomedical educational materials.

[Suicidality in German-speaking school psychiatry : Thematization in textbooks from 1803 until the present].

PubMed

Gnoth, M; Glaesmer, H; Steinberg, H

2017-10-05

This chronology gives an overview about continuities and changes in the perception of suicidality in German-speaking school psychiatry over the past 200+ years. This study was guided by the following questions: has suicidality been perceived as regularly being connected to certain mental illnesses? Which other possible causes have been discussed by psychiatrists from the nineteenth century to the beginning of the twenty-first century? What approaches have major psychiatrists adopted towards suicidal patients and threatened suicide? What treatment and preventive strategies have been suggested? First, we compiled a list of the, in our view, most influential textbooks on psychiatry of German-speaking school psychiatry from 1803 until the present. These textbooks were then skim-read for relevant passages on suicidality. The material gained was elicited, classified and analyzed in relation to the questions at hand. Futhermore, an attempt was made to arrive at contextual estimations. Several authors named a certain set of psychiatric illnesses that are assumed to involve or increase the risk of suicide. These illnesses include depression, schizophrenia and also physical illnesses. In nineteenth century textbooks heredity, anatomical anomalies and nationality were discussed as potential influencing factors. In contrast, more recent books discuss models of how suicidal behavior emerges and often refer to the Werther effect. With respect to therapy there is a trend towards therapeutic discussions and modern psychopharmacotherapy. Over time, there have been continuities and changes in psychiatrists' approach to suicidality not only as far as clinical aspects are concerned but also the general approach to and management of suicidal patients.

Generic Reference in English, Arabic and Malay: A Cross Linguistic Typology and Comparison

ERIC Educational Resources Information Center

AL-Malki, Eidhah Abdullah; Majid, Norazman Abdul; Omar, Noor Abidah Mohd

2014-01-01

According to the Longman Grammar of Spoken and Written English 1999 by Biber et al. (p. 266) generic article uses are more than twice as common in academic English than in conversation or fiction. This is an area that English for Academic Purpose (EPA) textbooks and teachers would need to target more than general English teaching. This paper is…

The Logical and Psychological Structure of Physical Chemistry and Its Relevance to the Organization/Sequencing of the Major Areas Covered in Physical Chemistry Textbooks

ERIC Educational Resources Information Center

Tsaparlis, Georgios

2014-01-01

Jensen's scheme for the logical structure of chemistry is taken as reference to study the logical structure of physical chemistry. The scheme distinguishes three dimensions (composition and structure, energy, and time), with each dimension treated at one of the three levels (molar, molecular, and electrical). Such a structure places the outer…

Implementation of Problem Based Learning Model in Concept Learning Mushroom as a Result of Student Learning Improvement Efforts Guidelines for Teachers

ERIC Educational Resources Information Center

Rubiah, Musriadi

2016-01-01

Problem based learning is a training strategy, students work together in groups, and take responsibility for solving problems in a professional manner. Instructional materials such as textbooks become the main reference of students in study of mushrooms, especially the material is considered less effective in responding to the information needs of…

El uso de escritos ensayisticos en clases de lengua espanola a nivel intermedio y superior (The Use of Written Essays in Intermediate and Advanced Level Spanish Language Classes).

ERIC Educational Resources Information Center

Busch, Hans Jorg

1994-01-01

Presents as an alternative to the traditional Spanish textbook a modular approach that consists of activities based on essay reading and grammar exercises. Students liked this form of instruction, and most indicated that they had learned material previously unknown to them. (seven references) (Author/CK)

Tracking clinical use of personal digital assistant reference resources.

PubMed

Pattillo, Robin E; Brewer, Marquette; Smith, Cheryl M

2007-01-01

Mechanisms are needed to evaluate the effectiveness of ever-increasing technological resources for nursing student use. The authors tracked the use of personal digital assistants versus textbook resources by junior-level baccalaureate nursing students throughout 1 semester. The authors discuss the results of that activity and provide a starting point for the evaluation of the use of personal digital assistants by nursing students.

JPRS Report, Soviet Union, Political Affairs, Republic Language Legislation.

DTIC Science & Technology

1989-12-05

reference materials ( dictionaries , termi- nology glossaries, phrase books, self-taught books, and so on), and qualified specialists in the field of...textbooks; d) to publish self-taught manuals, phrase books, and explanatory and bilingual dictionaries for the aid of persons desiring to study...Armenian. To create the nec- essary printing facility base to publish high-quality illus- trated dictionaries ; to provide uninterrupted delivery of

Use of the Primitive Unit Cell in Understanding Subtle Features of the Cubic Closest-Packed Structure

ERIC Educational Resources Information Center

Hawkins, John A.; Rittenhouse, Jeffrey L.; Soper, Linda M.; Rittenhouse, Robert C.

2008-01-01

One of the most important crystal structures adopted by metals is characterized by the "abcabc"...stacking of close-packed layers. This structure is commonly referred to in textbooks as the cubic close-packed (ccp) or face-centered cubic (fcc) structure, since the entire lattice can be generated by replication of a face-centered cubic unit cell…

Novelty and Foreseeing Research Trends: The Case of Astrophysics and Astronomy

NASA Astrophysics Data System (ADS)

Varga, Attila

2018-05-01

Metrics based on reference lists of research articles or on keywords have been used to predict citation impact. The concept behind such metrics is that original ideas stem from the reconfiguration of the structure of past knowledge, and therefore atypical combinations in the reference lists, keywords, or classification codes indicate future high-impact research. The current paper serves as an introduction to this line of research for astronomers and also addresses some of the methodological questions in this field of innovation studies. It is still not clear if the choice of particular indexes, such as references to journals, articles, or specific bibliometric classification codes affects the relationship between atypical combinations and citation impact. To understand more aspects of the innovation process, a new metric has been devised to measure to what extent researchers are able to anticipate the changing combinatorial trends of the future. Results show that the variant of the latter anticipation scores that is based on paper combinations is a good predictor of the future citation impact of scholarly works. The study also shows that the effects of tested indexes vary with the aggregation levels that were used to construct them. A detailed analysis of combinatorial novelty in the field reveals that certain sub-fields of astronomy and astrophysics have different roles in the reconfiguration of past knowledge.

Comparing the development of the multiplication of fractions in Turkish and American textbooks

NASA Astrophysics Data System (ADS)

Kar, Tuğrul; Güler, Gürsel; Şen, Ceylan; Özdemir, Ercan

2018-02-01

This study analyzed the methods used to teach the multiplication of fractions in Turkish and American textbooks. Two Turkish textbooks and two American textbooks, Everyday Mathematics (EM) and Connected Mathematics 3 (CM), were analyzed. The analyses focused on the content and the nature of the mathematical problems presented in the textbooks. The findings of the study showed that the American textbooks aimed at developing conceptual understanding first and then procedural fluency, whereas the Turkish textbooks aimed at developing both concurrently. The American textbooks provided more opportunities for different computational strategies. The solutions to most problems in all textbooks required a single computational step, a numerical answer, and procedural knowledge. Furthermore, compared with the Turkish textbooks, the American textbooks contained a greater number of problems that required high-level cognitive skills such as mathematical reasoning.

A Study of Trends of College English Reading Textbooks in Japan: An Analysis of College English Reading Textbooks for 1985.

ERIC Educational Resources Information Center

Kitao, Kenji; And Others

A study of reading textbooks for English as a second language published in Japan evaluated 150 traditional reading textbooks and 32 new reading textbooks published for use in 1985. Traditional reading textbooks are those with main texts and notes and sometimes a few comprehension questions. New reading textbooks have main texts, comprehension…

Quantitative Modeling of Earth Surface Processes

NASA Astrophysics Data System (ADS)

Pelletier, Jon D.

This textbook describes some of the most effective and straightforward quantitative techniques for modeling Earth surface processes. By emphasizing a core set of equations and solution techniques, the book presents state-of-the-art models currently employed in Earth surface process research, as well as a set of simple but practical research tools. Detailed case studies demonstrate application of the methods to a wide variety of processes including hillslope, fluvial, aeolian, glacial, tectonic, and climatic systems. Exercises at the end of each chapter begin with simple calculations and then progress to more sophisticated problems that require computer programming. All the necessary computer codes are available online at www.cambridge.org/9780521855976. Assuming some knowledge of calculus and basic programming experience, this quantitative textbook is designed for advanced geomorphology courses and as a reference book for professional researchers in Earth and planetary science looking for a quantitative approach to Earth surface processes.

Experimental Evaluation of Textbooks and Multimedia.

ERIC Educational Resources Information Center

Mikk, Jaan

This paper begins by providing an overview of three types of textbook research methods: asking teachers, parents, or students about the different aspects of textbook quality; textbook analysis, i.e. counting some characteristics of a textbook using strictly fixed rules; and the experimental evaluation of textbooks, usually carried out in schools.…

Advancing Suicide Prevention Research With Rural American Indian and Alaska Native Populations

PubMed Central

Chandler, Michael; Gone, Joseph P.; Cwik, Mary; Kirmayer, Laurence J.; LaFromboise, Teresa; Brockie, Teresa; O’Keefe, Victoria; Walkup, John; Allen, James

2015-01-01

As part of the National Action Alliance for Suicide Prevention’s American Indian and Alaska Native (AI/AN) Task Force, a multidisciplinary group of AI/AN suicide research experts convened to outline pressing issues related to this subfield of suicidology. Suicide disproportionately affects Indigenous peoples, and remote Indigenous communities can offer vital and unique insights with relevance to other rural and marginalized groups. Outcomes from this meeting include identifying the central challenges impeding progress in this subfield and a description of promising research directions to yield practical results. These proposed directions expand the alliance’s prioritized research agenda and offer pathways to advance the field of suicide research in Indigenous communities and beyond. PMID:25790403

Open Textbook Proof-of-Concept via Connexions

ERIC Educational Resources Information Center

Baker, Judy; Thierstein, Joel; Fletcher, Kathi; Kaur, Manpreet; Emmons, Jonathan

2009-01-01

To address the high cost of textbooks, Rice University's Connexions and the Community College Open Textbook Project (CCOTP) collaborated to develop a proof-of-concept free and open textbook. The proof-of-concept served to document a workflow process that would support adoption of open textbooks. Open textbooks provide faculty and students with a…

Comparative analysis of knowledge representation and reasoning requirements across a range of life sciences textbooks.

PubMed

Chaudhri, Vinay K; Elenius, Daniel; Goldenkranz, Andrew; Gong, Allison; Martone, Maryann E; Webb, William; Yorke-Smith, Neil

2014-01-01

Using knowledge representation for biomedical projects is now commonplace. In previous work, we represented the knowledge found in a college-level biology textbook in a fashion useful for answering questions. We showed that embedding the knowledge representation and question-answering abilities in an electronic textbook helped to engage student interest and improve learning. A natural question that arises from this success, and this paper's primary focus, is whether a similar approach is applicable across a range of life science textbooks. To answer that question, we considered four different textbooks, ranging from a below-introductory college biology text to an advanced, graduate-level neuroscience textbook. For these textbooks, we investigated the following questions: (1) To what extent is knowledge shared between the different textbooks? (2) To what extent can the same upper ontology be used to represent the knowledge found in different textbooks? (3) To what extent can the questions of interest for a range of textbooks be answered by using the same reasoning mechanisms? Our existing modeling and reasoning methods apply especially well both to a textbook that is comparable in level to the text studied in our previous work (i.e., an introductory-level text) and to a textbook at a lower level, suggesting potential for a high degree of portability. Even for the overlapping knowledge found across the textbooks, the level of detail covered in each textbook was different, which requires that the representations must be customized for each textbook. We also found that for advanced textbooks, representing models and scientific reasoning processes was particularly important. With some additional work, our representation methodology would be applicable to a range of textbooks. The requirements for knowledge representation are common across textbooks, suggesting that a shared semantic infrastructure for the life sciences is feasible. Because our representation overlaps heavily with those already being used for biomedical ontologies, this work suggests a natural pathway to include such representations as part of the life sciences curriculum at different grade levels.

The neglected cranial nerve: nervus terminalis (cranial nerve N).

PubMed

Vilensky, Joel A

2014-01-01

The nervus terminalis (NT; terminal nerve) was clearly identified as an additional cranial nerve in humans more than a century ago yet remains mostly undescribed in modern anatomy textbooks. The nerve is referred to as the nervus terminalis because in species initially examined its fibers were seen entering the brain in the region of the lamina terminalis. It has also been referred to as cranial nerve 0, but because there is no Roman symbol for zero, an N for the Latin word nulla is a better numerical designation. This nerve is very distinct in human fetuses and infants but also has been repeatedly identified in adult human brains. The NT fibers are unmyelinated and emanate from ganglia. The fibers pass through the cribriform plate medial to those of the olfactory nerve fila. The fibers end in the nasal mucosa and probably arise from autonomic/neuromodulatory as well as sensory neurons. The NT has been demonstrated to release luteinizing-releasing luteinizing hormone and is therefore thought to play a role in reproductive behavior. Based on the available evidence, the NT appears to be functional in adult humans and should be taught in medical schools and incorporated into anatomy/neuroanatomy textbooks. Copyright © 2012 Wiley Periodicals, Inc., a Wiley company.

[Printed material distributed by pharmaceutical propaganda agents].

PubMed

Mejía, R; Avalos, A

2001-01-01

Pharmaceutical sales representatives (drug reps) frequently visit 70% to 90% of physicians during their daily clinical practice and many consider the promotional printed material to be a major source of clinical information. We evaluated samples of the promotional printed material distributed to physicians by drug reps in order to determine whether the data contained in the promotional material is correct and supported by references accessible in Argentina. A consecutive sample of all the promotional material distributed by drug reps in the general internal medicine program (Hospital de Clínicas) was collected between March 15 and April 15, 2000. Reprints and monographs were excluded. Clinical information was reviewed by two general internists and compared to information in a major pharmacology textbook and in an electronic medical information program. References cited were reviewed for correct listing and accessibility in any of the four major medical libraries in Buenos Aires. Of the sixty-four pieces of promotional material collected, thirty were randomly selected and evaluated. In twenty one (70%) the therapeutic effect promoted in advertisement appeared in Goodman & Gilman's 9th edition textbook of pharmacology, in the pharmacology section of the Up-to-Date version 8.1 or in both. Only eighteen (60%) of the thirty promotional printed material evaluated had statements supported by cited references. From a total of 131 references cited in promotional materials, sixty (46%) were incorrectly listed according to the International Committee of Medical Journal Editors. These references were inaccessible. Of the 71 references correctly cited, 49 (69%) were not available in any of the four major medical libraries in Buenos Aires and 8 were available in only two of the libraries. Twenty-two references were reviewed, and in twelve of these (54%), the objective of the research study concurred with the statement of the promotional printed material. Adverse reactions, warnings about drug interactions and contraindications were absent from all promotional printed material. It can be concluded that the promotional printed material distributed by the drug reps in Buenos Aires are biased and provide misinformation more often than not. We recommend that practicing physicians routinely disregard promotional printed material as a source of clinical information.

β-Adrenergic Control of Hippocampal Function: Subserving the Choreography of Synaptic Information Storage and Memory

PubMed Central

Hagena, Hardy; Hansen, Niels; Manahan-Vaughan, Denise

2016-01-01

Noradrenaline (NA) is a key neuromodulator for the regulation of behavioral state and cognition. It supports learning by increasing arousal and vigilance, whereby new experiences are “earmarked” for encoding. Within the hippocampus, experience-dependent information storage occurs by means of synaptic plasticity. Furthermore, novel spatial, contextual, or associative learning drives changes in synaptic strength, reflected by the strengthening of long-term potentiation (LTP) or long-term depression (LTD). NA acting on β-adrenergic receptors (β-AR) is a key determinant as to whether new experiences result in persistent hippocampal synaptic plasticity. This can even dictate the direction of change of synaptic strength. The different hippocampal subfields play different roles in encoding components of a spatial representation through LTP and LTD. Strikingly, the sensitivity of synaptic plasticity in these subfields to β-adrenergic control is very distinct (dentate gyrus > CA3 > CA1). Moreover, NA released from the locus coeruleus that acts on β-AR leads to hippocampal LTD and an enhancement of LTD-related memory processing. We propose that NA acting on hippocampal β-AR, that is graded according to the novelty or saliency of the experience, determines the content and persistency of synaptic information storage in the hippocampal subfields and therefore of spatial memories. PMID:26804338

Finasteride for chronic central serous chorioretinopathy.

PubMed

Forooghian, Farzin; Meleth, Annal D; Cukras, Catherine; Chew, Emily Y; Wong, Wai T; Meyerle, Catherine B

2011-04-01

To evaluate the safety and efficacy of finasteride, an inhibitor of dihydrotestosterone synthesis, in the treatment of chronic central serous chorioretinopathy. Five patients with chronic central serous chorioretinopathy were prospectively enrolled in this pilot study. Patients were administered finasteride (5 mg) daily for 3 months, after which study medication was withheld and patients were observed for 3 months. Main outcome measures included best-corrected visual acuity, central subfield macular thickness, and subretinal fluid volume as assessed by optical coherence tomography. Serum dihydrotestosterone, serum testosterone, and urinary cortisol were also measured. There was no change in mean best-corrected visual acuity. Mean center-subfield macular thickness and subretinal fluid volume reached a nadir at 3 months and rose to levels that were below baseline by 6 months. The changes in both optical coherence tomography parameters paralleled those in serum dihydrotestosterone level. In four patients, center-subfield macular thickness and/or subretinal fluid volume increased after discontinuation of finasteride. In the remaining patient, both optical coherence tomography parameters normalized with finasteride and remained stable when the study medication was discontinued. Finasteride may represent a novel medical treatment for chronic central serous chorioretinopathy. Larger controlled clinical trials are needed to further assess the efficacy of finasteride for the treatment of central serous chorioretinopathy.

Finasteride for Chronic Central Serous Chorioretinopathy

PubMed Central

Forooghian, Farzin; Meleth, Annal D.; Cukras, Catherine; Chew, Emily Y.; Wong, Wai T.; Meyerle, Catherine B.

2010-01-01

Purpose To evaluate the safety and efficacy of finasteride, an inhibitor of dihyroxytestosterone (DHT) synthesis, in the treatment of chronic central serous chorioretinopathy (CSC). Methods Five patients with chronic CSC were prospectively enrolled in this pilot study. Patients were administered finasteride (5mg) daily for 3 months, following which study medication was withheld and patients were observed for 3 months. Main outcome measures included best-corrected visual acuity (BCVA), center-subfield macular thickness and subretinal fluid volume as assessed by optical coherence tomography (OCT). Serum DHT, serum testosterone, and urinary cortisol were also measured. Results There was no change in mean BCVA. Mean center-subfield macular thickness and subretinal fluid volume reached a nadir at 3 months, and rose to levels that were below baseline by 6 months. The changes in both OCT parameters paralleled changes in serum DHT level. In four patients, center-subfield macular thickness and/or subretinal fluid volume increased following discontinuation of finasteride. In the remaining patient, both OCT parameters normalized with finasteride and remained stable when the study medication was discontinued. Conclusion Finasteride may represent a novel medical treatment for chronic CSC. Larger controlled clinical trials are needed to further assess the efficacy of finasteride for the treatment of CSC. Summary Pilot study to evaluate finasteride for treatment of chronic central serous chorioretinopathy suggests efficacy and tolerability. PMID:21273946

Revision Cycles for Economics Textbooks: An Application of the Theory of Durable Goods Monopoly

ERIC Educational Resources Information Center

Li, Xin

2011-01-01

In this dissertation, I study economics textbook markets as an example of durable goods monopoly. Textbooks are protected by copyrights, and from a student's point of view, different textbooks are not good substitutes because students wish to use the textbook adopted by their instructors. Therefore sellers have market power. Textbooks can be…

OER Quality and Adaptation in K-12: Comparing Teacher Evaluations of Copyright-Restricted, Open, and Open/Adapted Textbooks

ERIC Educational Resources Information Center

Kimmons, Royce

2015-01-01

Conducted in conjunction with an institute on open textbook adaptation, this study compares textbook evaluations from practicing K-12 classroom teachers (n = 30) on three different types of textbooks utilized in their contexts: copyright-restricted, open, and open/adapted. Copyright-restricted textbooks consisted of those textbooks already in use…

Journey to Textbook Affordability: An Investigation of Students' Use of eTextbooks at Multiple Campuses

ERIC Educational Resources Information Center

Baek, Eun-Ok; Monaghan, James

2013-01-01

eTextbooks have steadily and recently more rapidly penetrated the textbook market. In order to effectively support students' learning, it is important to comprehend students' experiences using eTextbooks. This survey study was designed to gain an understanding of students' experiences in using eTextbooks and variables that impact their…

History Textbooks at the New Century: A Report of the American Textbook Council.

ERIC Educational Resources Information Center

Sewall, Gilbert T.

The American Textbook Council identified the nation's leading social studies textbooks based on estimated volume of sales and on adoptions in California, Indiana, North Carolina, Florida, and New York. Three multi-volume elementary-level programs and about a dozen secondary-level history textbooks command the market. The history textbooks at the…

Analysis of a Typical Chinese High School Biology Textbook Using the AAAS Textbook Standards

ERIC Educational Resources Information Center

Liang, Ye; Cobern, William W.

2013-01-01

The purpose of this study was to evaluate a typical Chinese high school biology textbook using the textbook standards of the American Association for the Advancement of Science (AAAS). The data were composed of three chapters selected from the textbook. Each chapter was analyzed and rated using the AAAS textbook standards. Pearson correlations…

"Are you gonna publish that?" Peer-reviewed publication outcomes of doctoral dissertations in psychology.

PubMed

Evans, Spencer C; Amaro, Christina M; Herbert, Robyn; Blossom, Jennifer B; Roberts, Michael C

2018-01-01

If a doctoral dissertation represents an original investigation that makes a contribution to one's field, then dissertation research could, and arguably should, be disseminated into the scientific literature. However, the extent and nature of dissertation publication remains largely unknown within psychology. The present study investigated the peer-reviewed publication outcomes of psychology dissertation research in the United States. Additionally, we examined publication lag, scientific impact, and variations across subfields. To investigate these questions, we first drew a stratified random cohort sample of 910 psychology Ph.D. dissertations from ProQuest Dissertations & Theses. Next, we conducted comprehensive literature searches for peer-reviewed journal articles derived from these dissertations published 0-7 years thereafter. Published dissertation articles were coded for their bibliographic details, citation rates, and journal impact metrics. Results showed that only one-quarter (25.6% [95% CI: 23.0, 28.4]) of dissertations were ultimately published in peer-reviewed journals, with significant variations across subfields (range: 10.1 to 59.4%). Rates of dissertation publication were lower in professional/applied subfields (e.g., clinical, counseling) compared to research/academic subfields (e.g., experimental, cognitive). When dissertations were published, however, they often appeared in influential journals (e.g., Thomson Reuters Impact Factor M = 2.84 [2.45, 3.23], 5-year Impact Factor M = 3.49 [3.07, 3.90]) and were cited numerous times (Web of Science citations per year M = 3.65 [2.88, 4.42]). Publication typically occurred within 2-3 years after the dissertation year. Overall, these results indicate that the large majority of Ph.D. dissertation research in psychology does not get disseminated into the peer-reviewed literature. The non-publication of dissertation research appears to be a systemic problem affecting both research and training in psychology. Efforts to improve the quality and "publishability" of doctoral dissertation research could benefit psychological science on multiple fronts.

"Are you gonna publish that?" Peer-reviewed publication outcomes of doctoral dissertations in psychology

PubMed Central

Amaro, Christina M.; Herbert, Robyn; Blossom, Jennifer B.; Roberts, Michael C.

2018-01-01

If a doctoral dissertation represents an original investigation that makes a contribution to one’s field, then dissertation research could, and arguably should, be disseminated into the scientific literature. However, the extent and nature of dissertation publication remains largely unknown within psychology. The present study investigated the peer-reviewed publication outcomes of psychology dissertation research in the United States. Additionally, we examined publication lag, scientific impact, and variations across subfields. To investigate these questions, we first drew a stratified random cohort sample of 910 psychology Ph.D. dissertations from ProQuest Dissertations & Theses. Next, we conducted comprehensive literature searches for peer-reviewed journal articles derived from these dissertations published 0–7 years thereafter. Published dissertation articles were coded for their bibliographic details, citation rates, and journal impact metrics. Results showed that only one-quarter (25.6% [95% CI: 23.0, 28.4]) of dissertations were ultimately published in peer-reviewed journals, with significant variations across subfields (range: 10.1 to 59.4%). Rates of dissertation publication were lower in professional/applied subfields (e.g., clinical, counseling) compared to research/academic subfields (e.g., experimental, cognitive). When dissertations were published, however, they often appeared in influential journals (e.g., Thomson Reuters Impact Factor M = 2.84 [2.45, 3.23], 5-year Impact Factor M = 3.49 [3.07, 3.90]) and were cited numerous times (Web of Science citations per year M = 3.65 [2.88, 4.42]). Publication typically occurred within 2–3 years after the dissertation year. Overall, these results indicate that the large majority of Ph.D. dissertation research in psychology does not get disseminated into the peer-reviewed literature. The non-publication of dissertation research appears to be a systemic problem affecting both research and training in psychology. Efforts to improve the quality and “publishability” of doctoral dissertation research could benefit psychological science on multiple fronts. PMID:29444130

[Hippocampal subfield volume alteration in post-traumatic stress disorder: a magnetic resonance imaging study].

PubMed

Lu, Lu; Zhang, Lianqing; Hu, Xinyu; Hu, Xiaoxiao; Li, Lingjiang; Gong, Qiyong; Huang, Xiaoqi

2018-04-01

In the current study, we aim to investigate whether post-traumatic stress disorder (PTSD) is associated with structural alterations in specific subfields of hippocampus comparing with trauma-exposed control (TC) in a relatively large sample. We included 67 PTSD patients who were diagnosed under Diagnostic and Statistical Manual of Mental Disorders (4th Edition) (DSM-Ⅳ) criteria and 78 age- and sex-matched non-PTSD adult survivors who experienced similar stressors. High resolution T1 weighted images were obtained via a GE 3.0 T scanner. The structural data was automatically segmented using FreeSurfer software, and volume of whole hippocampus and subfield including CA1, CA2-3, CA4-DG, fimbria, presubiculum, subiculum and fissure were extracted. Volume differences between the two groups were statistically compared with age, years of education, duration from the events and intracranial volume (ICV) as covariates. Hemisphere, sex and diagnosis were entered as fixed factors. Relationship between morphometric measurements with Clinician-Administered PTSD Scale (CAPS) score and illness duration were performed using Pearson's correlation with SPSS. Comparing to TC, PTSD patients showed no statistically significant alteration in volumes of the whole hippocampus and all the subfields ( P > 0.05). In male patients, there were significant correlations between CAPS score and volume of right CA2-3 ( R 2 = 0.197, P = 0.034), right subiculum ( R 2 = 0.245, P = 0.016), and duration statistically correlated with right fissure ( R 2 = 0.247, P = 0.016). In female patients, CAPS scores significant correlated with volume of left presubiculum ( R 2 = 0.095, P = 0.042), left subiculum ( R 2 = 0.090, P = 0.048), and left CA4-DG ( R 2 = 0.099, P = 0.037). The main findings of the current study suggest that stress event causes non-selective damage to hippocampus in both PTSD patients and TC, and gender-specific lateralization may underlie PTSD pathology.

Impact of hippocampal subfield histopathology in episodic memory impairment in mesial temporal lobe epilepsy and hippocampal sclerosis.

PubMed

Comper, Sandra Mara; Jardim, Anaclara Prada; Corso, Jeana Torres; Gaça, Larissa Botelho; Noffs, Maria Helena Silva; Lancellotti, Carmen Lúcia Penteado; Cavalheiro, Esper Abrão; Centeno, Ricardo Silva; Yacubian, Elza Márcia Targas

2017-10-01

The objective of the study was to analyze preoperative visual and verbal episodic memories in a homogeneous series of patients with mesial temporal lobe epilepsy (MTLE) and unilateral hippocampal sclerosis (HS) submitted to corticoamygdalohippocampectomy and its association with neuronal cell density of each hippocampal subfield. The hippocampi of 72 right-handed patients were collected and prepared for histopathological examination. Hippocampal sclerosis patterns were determined, and neuronal cell density was calculated. Preoperatively, two verbal and two visual memory tests (immediate and delayed recalls) were applied, and patients were divided into two groups, left and right MTLE (36/36). There were no statistical differences between groups regarding demographic and clinical data. Cornu Ammonis 4 (CA4) neuronal density was significantly lower in the right hippocampus compared with the left (p=0.048). The groups with HS presented different memory performance - the right HS were worse in visual memory test [Complex Rey Figure, immediate (p=0.001) and delayed (p=0.009)], but better in one verbal task [RAVLT delayed (p=0.005)]. Multiple regression analysis suggested that the verbal memory performance of the group with left HS was explained by CA1 neuronal density since both tasks were significantly influenced by CA1 [Logical Memory immediate recall (p=0.050) and Logical Memory and RAVLT delayed recalls (p=0.004 and p=0.001, respectively)]. For patients with right HS, both CA1 subfield integrity (p=0.006) and epilepsy duration (p=0.012) explained Complex Rey Figure immediate recall performance. Ultimately, epilepsy duration also explained the performance in the Complex Rey Figure delayed recall (p<0.001). Cornu Ammonis 1 (CA1) hippocampal subfield was related to immediate and delayed recalls of verbal memory tests in left HS, while CA1 and epilepsy duration were associated with visual memory performance in patients with right HS. Copyright © 2017 Elsevier Inc. All rights reserved.

Comparison of the Impact of Wikipedia, UpToDate, and a Digital Textbook on Short-Term Knowledge Acquisition Among Medical Students: Randomized Controlled Trial of Three Web-Based Resources

PubMed Central

Wang, Christopher; Keren, Daniela; Tsui, Cindy; Garg, Ankit; Brar, Simarjeet; Valoo, Kamesha; Bonert, Michael; de Wolff, Jacob F; Heilman, James

2017-01-01

Background Web-based resources are commonly used by medical students to supplement curricular material. Three commonly used resources are UpToDate (Wolters Kluwer Inc), digital textbooks, and Wikipedia; there are concerns, however, regarding Wikipedia’s reliability and accuracy. Objective The aim of this study was to evaluate the impact of Wikipedia use on medical students’ short-term knowledge acquisition compared with UpToDate and a digital textbook. Methods This was a prospective, nonblinded, three-arm randomized trial. The study was conducted from April 2014 to December 2016. Preclerkship medical students were recruited from four Canadian medical schools. Convenience sampling was used to recruit participants through word of mouth, social media, and email. Participants must have been enrolled in their first or second year of medical school at a Canadian medical school. After recruitment, participants were randomized to one of the three Web-based resources: Wikipedia, UpToDate, or a digital textbook. During testing, participants first completed a multiple-choice questionnaire (MCQ) of 25 questions emulating a Canadian medical licensing examination. During the MCQ, participants took notes on topics to research. Then, participants researched topics and took written notes using their assigned resource. They completed the same MCQ again while referencing their notes. Participants also rated the importance and availability of five factors pertinent to Web-based resources. The primary outcome measure was knowledge acquisition as measured by posttest scores. The secondary outcome measures were participants’ perceptions of importance and availability of each resource factor. Results A total of 116 medical students were recruited. Analysis of variance of the MCQ scores demonstrated a significant interaction between time and group effects (P<.001, ηg2=0.03), with the Wikipedia group scoring higher on the MCQ posttest compared with the textbook group (P<.001, d=0.86). Access to hyperlinks, search functions, and open-source editing were rated significantly higher by the Wikipedia group compared with the textbook group (P<.001). Additionally, the Wikipedia group rated open access editing significantly higher than the UpToDate group; expert editing and references were rated significantly higher by the UpToDate group compared with the Wikipedia group (P<.001). Conclusions Medical students who used Wikipedia had superior short-term knowledge acquisition compared with those who used a digital textbook. Additionally, the Wikipedia group trended toward better posttest performance compared with the UpToDate group, though this difference was not significant. There were no significant differences between the UpToDate group and the digital textbook group. This study challenges the view that Wikipedia should be discouraged among medical students, instead suggesting a potential role in medical education. PMID:29089291

Textbooks: Prospects for the Technological Era.

ERIC Educational Resources Information Center

Bettex, Maurice

1995-01-01

Examines why textbooks will survive despite competition from new technological inventions. Discusses opposition to textbooks through the development of audiovisual aids, multimedia, and interactivity; advantages of textbooks over other educational media; development of print media; five principles for developing textbook content; and future…

Can an Electronic Textbooks Be Part of K-12 Education?: Challenges, Technological Solutions and Open Issues

ERIC Educational Resources Information Center

Lee, HeeJeong Jasmine; Messom, Chris; Yau, Kok-Lim Alvin

2013-01-01

An electronic textbook (e-Textbook) is a digitized (or electronic) form of textbook, which normally needs an endorsement by the national or state government when it is used in the K-12 education system. E-Textbooks have been envisioned to replace existing paper-based textbooks due to its educational advantages. Hence, it is of paramount importance…

25 CFR 36.41 - Standard XIV-Textbooks.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Standard XIV—Textbooks. (a) Each school shall establish a textbook review committee composed of teachers, parents, and students, and school board members. Appointment to the textbook review committee shall be subject to school board approval. (b) The textbook review committee shall establish a procedure and...

The New Paradox of the College Textbook.

ERIC Educational Resources Information Center

Lichtenberg, James

1992-01-01

As college textbooks have become more attractive, sophisticated, and useful, the textbook industry is suffering from high costs, increased popularity of used books, effects of rapidly advancing information and instructional technology, the atypical business structure of the college textbook market, and changing textbook development processes. (MSE)

Sex Moderates the Impact of Diagnosis and Amyloid PET Positivity on Hippocampal Subfield Volume.

PubMed

Caldwell, Jessica Z K; Berg, Jody-Lynn; Shan, Guogen; Cummings, Jeffrey L; Banks, Sarah J

2018-01-01

We examined moderation effects of sex and diagnosis on the effect of positive florbetapir positron emission tomography (PET) amyloid-β (Aβ) scan (A+) on hippocampus subfield volumes in 526 normal control (NC) and early mild cognitive impairment (eMCI) participants from the Alzheimer's Disease Neuroimaging Initiative (ADNI2; ADNI-GO). Regression moderation models showed that women- but not men- with NC designation did not show reduced subiculum volumes despite A+. At the eMCI stage, A+ was detrimental across sexes. Findings were significant while accounting for the effects of age, cognition at screening, education, and APOE4 carrier status. These findings suggest that women with A+ have early neural resistance to Alzheimer's disease-related amyloid burden.

Terminology of the tonsils.

PubMed

Casteleyn, C; Simoens, P; Van den Broeck, W

2011-06-01

Many terms used for referring to tonsillar structures are applied in immunological research. However, in many cases, the use of these terms is not in compliance with official veterinary anatomical nomenclature. This is partly attributable to ambiguous descriptions present in conventional anatomical textbooks. This study gives an overview of pertaining controversial terms and promotes the official anatomical terminology applicable to the tonsils, to enhance the unequivocal transfer of knowledge generated during immunological research. © 2011 Blackwell Verlag GmbH.

Rating the Quality of Open Textbooks: How Reviewer and Text Characteristics Predict Ratings

ERIC Educational Resources Information Center

Fischer, Lane; Ernst, David; Mason, Stacie

2017-01-01

Using data collected from peer reviews for Open Textbook Library titles, this paper explores questions about rating the quality of open textbooks. The five research questions addressed the relationship between textbook and reviewer characteristics and ratings. Although reviewers gave textbooks high ratings generally, reviewers identified…

World History Textbooks: A Review

ERIC Educational Resources Information Center

Sewall, Gilbert T.

2004-01-01

This world history review examines standard textbooks used between the sixth and twelfth grades in schools across the nation. These established textbooks dominate the field and set the pitch for new and forthcoming volumes. The 2002 Texas history textbook adoption and the California list have influenced what textbooks will dominate the national…

Effects of E-Textbook Instructor Annotations on Learner Performance

ERIC Educational Resources Information Center

Dennis, Alan R.; Abaci, Serdar; Morrone, Anastasia S.; Plaskoff, Joshua; McNamara, Kelly O.

2016-01-01

With additional features and increasing cost advantages, e-textbooks are becoming a viable alternative to paper textbooks. One important feature offered by enhanced e-textbooks (e-textbooks with interactive functionality) is the ability for instructors to annotate passages with additional insights. This paper describes a pilot study that examines…

The Future of E-Textbooks

ERIC Educational Resources Information Center

Lokar, Matija

2015-01-01

Electronic versions of textbooks (e-textbooks) have recently become a hot topic in the educational community. A good e-textbook should be quite different from a printed textbook. It should provide much more besides the obvious additions and improvements such as interactivity, multimedia, and ease of navigation. As the need for individual approach…

An Investigation of the Communicative Approach Teaching in Primary English Textbooks in Hong Kong and Malaysia: A Search into Communicative Language Teaching (CLT) Textbooks, and How CLT Is Applied in Textbooks

ERIC Educational Resources Information Center

Ko, Charles

2014-01-01

In the present research, it will be shown how grammar activities in textbooks still retain the structural method of teaching grammar. The results found by previous scholars' research will be covered, and illustrated by excerpts of textbooks, including comparison of Hong Kong and Malaysian textbooks. Communicative Language Teaching (CLT)…

Paper-Based Textbooks with Audio Support for Print-Disabled Students.

PubMed

Fujiyoshi, Akio; Ohsawa, Akiko; Takaira, Takuya; Tani, Yoshiaki; Fujiyoshi, Mamoru; Ota, Yuko

2015-01-01

Utilizing invisible 2-dimensional codes and digital audio players with a 2-dimensional code scanner, we developed paper-based textbooks with audio support for students with print disabilities, called "multimodal textbooks." Multimodal textbooks can be read with the combination of the two modes: "reading printed text" and "listening to the speech of the text from a digital audio player with a 2-dimensional code scanner." Since multimodal textbooks look the same as regular textbooks and the price of a digital audio player is reasonable (about 30 euro), we think multimodal textbooks are suitable for students with print disabilities in ordinary classrooms.

INSTRUCTIONAL MANUALS OF BOUNDARY‐WORK: PSYCHOLOGY TEXTBOOKS, STUDENT SUBJECTIVITIES, AND DISCIPLINARY HISTORIOGRAPHIES

PubMed Central

FLIS, IVAN

2016-01-01

This article aims to provide an overview of the historiography of psychology textbooks. In the overview, I identify and describe in detail two strands of writing histories of introductory textbooks of psychology and juxtapose them to provide an integrated historiography of textbooks in psychology. One strand is developed by teachers of psychology—first as a general approach for investigating textbooks in a pedagogical setting, and then later upgraded into a full history of psychology textbooks in America. The other strand follows a more familiar perspective of historians of science and historians of psychology who build on various post‐Kuhnian and post‐Foucauldian perspectives on textbooks. I make an argument for integrating these two views for a more comprehensive historiography of textbooks in psychology, recasting textbooks as objects of research and sources that are interesting sui generis for historians of psychology in their investigations. PMID:27152736

[Theoretical and methodological uses of research in Social and Human Sciences in Health].

PubMed

Deslandes, Suely Ferreira; Iriart, Jorge Alberto Bernstein

2012-12-01

The current article aims to map and critically reflect on the current theoretical and methodological uses of research in the subfield of social and human sciences in health. A convenience sample was used to select three Brazilian public health journals. Based on a reading of 1,128 abstracts published from 2009 to 2010, 266 articles were selected that presented the empirical base of research stemming from social and human sciences in health. The sample was classified thematically as "theoretical/ methodological reference", "study type/ methodological design", "analytical categories", "data production techniques", and "analytical procedures". We analyze the sample's emic categories, drawing on the authors' literal statements. All the classifications and respective variables were tabulated in Excel. Most of the articles were self-described as qualitative and used more than one data production technique. There was a wide variety of theoretical references, in contrast with the almost total predominance of a single type of data analysis (content analysis). In several cases, important gaps were identified in expounding the study methodology and instrumental use of the qualitative research techniques and methods. However, the review did highlight some new objects of study and innovations in theoretical and methodological approaches.

To what do psychiatric diagnoses refer? A two-dimensional semantic analysis of diagnostic terms

PubMed Central

Maung, Hane Htut

2016-01-01

In somatic medicine, diagnostic terms often refer to the disease processes that are the causes of patients' symptoms. The language used in some clinical textbooks and health information resources suggests that this is also sometimes assumed to be the case with diagnoses in psychiatry. However, this seems to be in tension with the ways in which psychiatric diagnoses are defined in diagnostic manuals, according to which they refer solely to clusters of symptoms. This paper explores how theories of reference in the philosophy of language can help to resolve this tension. After the evaluation of descriptive and causal theories of reference, I put forward a conceptual framework based on two-dimensional semantics that allows the causal analysis of diagnostic terms in psychiatry, while taking seriously their descriptive definitions in diagnostic manuals. While the framework is presented as a solution to a problem regarding the semantics of psychiatric diagnoses, it can also accommodate the analysis of diagnostic terms in other medical disciplines. PMID:26580354

An open-source textbook for teaching climate-related risk analysis using the R computing environment

NASA Astrophysics Data System (ADS)

Applegate, P. J.; Keller, K.

2015-12-01

Greenhouse gas emissions lead to increased surface air temperatures and sea level rise. In turn, sea level rise increases the risks of flooding for people living near the world's coastlines. Our own research on assessing sea level rise-related risks emphasizes both Earth science and statistics. At the same time, the free, open-source computing environment R is growing in popularity among statisticians and scientists due to its flexibility and graphics capabilities, as well as its large library of existing functions. We have developed a set of laboratory exercises that introduce students to the Earth science and statistical concepts needed for assessing the risks presented by climate change, particularly sea-level rise. These exercises will be published as a free, open-source textbook on the Web. Each exercise begins with a description of the Earth science and/or statistical concepts that the exercise teaches, with references to key journal articles where appropriate. Next, students are asked to examine in detail a piece of existing R code, and the exercise text provides a clear explanation of how the code works. Finally, students are asked to modify the existing code to produce a well-defined outcome. We discuss our experiences in developing the exercises over two separate semesters at Penn State, plus using R Markdown to interweave explanatory text with sample code and figures in the textbook.

Nursing Student Perceptions of Digital Textbooks: A Pilot Study.

PubMed

Mennenga, Heidi A

2016-01-01

Digital textbooks are increasing in popularity, often resulting from the perception that students demand the use of technology in academics. However, few studies have been done on student perceptions of digital textbooks. A pilot study was conducted with students enrolled in a nursing research course; 123 nursing students participated. This study found that students overwhelmingly preferred print textbooks over digital textbooks. More research needs to be done before assuming students would prefer digital textbooks over print.

A Role for Language Analysis in Mathematics Textbook Analysis

ERIC Educational Resources Information Center

O'Keeffe, Lisa; O'Donoghue, John

2015-01-01

In current textbook analysis research, there is a strong focus on the content, structure and expectation presented by the textbook as elements for analysis. This research moves beyond such foci and proposes a framework for textbook language analysis which is intended to be integrated into an overall framework for mathematics textbook analysis. The…

Methods of Use of an Online Economics Textbook

ERIC Educational Resources Information Center

Miller, Jon R.; Baker-Eveleth, Lori

2010-01-01

The rising cost of college textbooks over the last decade provides an opportunity for alternatives. Electronic or online textbooks are an effective substitute to the traditional paper-based textbooks, although students have been slow to transition to the new method. A custom, professor-written online textbook not only addresses the reduction in…

Who's Who in Introductory Psychology Textbooks: A Citation Analysis Redux

ERIC Educational Resources Information Center

Griggs, Richard A.; Christopher, Andrew N.

2016-01-01

It is important to assess periodically how introductory textbooks portray our discipline because introductory psychology is the most popular psychology course, almost all teachers use textbooks for it, and textbooks play a major role in defining the course for students. To do so, past studies have used textbook citation analyses. We analyzed…

Effectiveness of Electronic Textbooks with Embedded Activities on Student Learning

ERIC Educational Resources Information Center

Porter, Paula L.

2010-01-01

Current versions of electronic textbooks mimic the format and structure of printed textbooks; however, the electronic capabilities of these new versions of textbooks offer the potential of embedding interactive features of web-based learning within the context of a textbook. This dissertation research study was conducted to determine if student…

Studying Open versus Traditional Textbook Effects on Students' Course Performance: Confounds Abound

ERIC Educational Resources Information Center

Griggs, Richard A.; Jackson, Sherri L.

2017-01-01

To combat the high cost of textbooks, open (digitally free) textbooks have recently entered the textbook market. Griggs and Jackson (2017) reviewed the open introductory psychology textbooks presently available to provide interested teachers with essential information about these texts and how they compare with traditional (commercial)…

The Mad, Mad World of Textbook Adoption

ERIC Educational Resources Information Center

Thomas B Fordham Foundation and Institute, 2004

2004-01-01

Textbook Adoption: The process, in place in twenty-one states, of reviewing textbooks according to state guidelines and then mandating specific books that schools must use, or lists of approved textbooks that schools must choose from. It consistently produces second-rate textbooks that replicate the same flaws and failings over and over again.…

The Introductory Psychology Textbook Market: Perceptions of Authors and Editors.

ERIC Educational Resources Information Center

Griggs, Richard A.; Jackson, Sherri L.

1989-01-01

Surveys psychology textbook authors and editors on their perceptions of the introductory psychology textbook market. Finds that the textbook market is divided into three levels according to quality, and that authors and editors are not familiar with most textbooks. Notes that the growth of used book companies has adversely affected the market.…

Some Perceptions of English Geography Textbook Authors on Writing Textbooks

ERIC Educational Resources Information Center

Lee, Jongwon; Catling, Simon

2016-01-01

There has been much research into the nature and uses of school geography textbooks as teaching resources, yet the perceptions of their authors have been neglected. This study investigated the perspectives of a sample of authors of English primary and secondary school geography textbooks on their experiences as textbook authors. It enquired into…

Introductory Business Textbook Revision Cycles: Are They Getting Shorter?

ERIC Educational Resources Information Center

Zinser, Brian; Brunswick, Gary

2010-01-01

The rate of textbook revision cycles is examined in light of the recent trend towards more rapid revisions (and adoptions of textbooks). The authors conduct background research to better understand the context for textbook revision cycles and the environmental forces that have been influencing what appears to be more rapid textbook revisions. A…

Students' Intentions to Purchase Electronic Textbooks

ERIC Educational Resources Information Center

Stone, Robert W.; Baker-Eveleth, Lori J.

2013-01-01

Textbooks have played an important role in education for decades. Given the significant number of technology applications in education, it is not surprising that at least one such application is the electronic textbook (e-textbook). There are a variety of motivations to adopt an e-textbook, including frequent content updates and low costs. The…

Evolutionary developmental pathology and anthropology: A new field linking development, comparative anatomy, human evolution, morphological variations and defects, and medicine.

PubMed

Diogo, Rui; Smith, Christopher M; Ziermann, Janine M

2015-11-01

We introduce a new subfield of the recently created field of Evolutionary-Developmental-Anthropology (Evo-Devo-Anth): Evolutionary-Developmental-Pathology-and-Anthropology (Evo-Devo-P'Anth). This subfield combines experimental and developmental studies of nonhuman model organisms, biological anthropology, chordate comparative anatomy and evolution, and the study of normal and pathological human development. Instead of focusing on other organisms to try to better understand human development, evolution, anatomy, and pathology, it places humans as the central case study, i.e., as truly model organism themselves. We summarize the results of our recent Evo-Devo-P'Anth studies and discuss long-standing questions in each of the broader biological fields combined in this subfield, paying special attention to the links between: (1) Human anomalies and variations, nonpentadactyly, homeotic transformations, and "nearest neighbor" vs. "find and seek" muscle-skeleton associations in limb+facial muscles vs. other head muscles; (2) Developmental constraints, the notion of "phylotypic stage," internalism vs. externalism, and the "logic of monsters" vs. "lack of homeostasis" views about human birth defects; (3) Human evolution, reversions, atavisms, paedomorphosis, and peromorphosis; (4) Scala naturae, Haeckelian recapitulation, von Baer's laws, and parallelism between phylogeny and development, here formally defined as "Phylo-Devo parallelism"; and (5) Patau, Edwards, and Down syndrome (trisomies 13, 18, 21), atavisms, apoptosis, heart malformations, and medical implications. © 2015 Wiley Periodicals, Inc.

Association between cytokine levels, verbal memory and hippocampus volume in psychotic disorders and healthy controls.

PubMed

Hoseth, E Z; Westlye, L T; Hope, S; Dieset, I; Aukrust, P; Melle, I; Haukvik, U K; Agartz, I; Ueland, T; Ueland, T; Andreassen, O A

2016-01-01

We investigated whether elevated plasma levels of immune markers were associated with verbal memory and hippocampal subfield volumes in patients with severe mental illnesses and in healthy controls. In total, 230 patients with a broad DSM-IV schizophrenia spectrum illness or bipolar disorder and 236 healthy controls were recruited. Memory was assessed using the Wechsler Memory Scale-Third Edition (WMS-III) Logical Memory immediate and delayed recall, and the California Verbal Learning Test summed recall over learning list (CVLT learning) and delayed free recall. We measured plasma levels of soluble tumor necrosis factor receptor 1 (sTNF-R1), interleukin-1 receptor antagonist, interleukin-6, von Willebrand factor, osteoprotegerin, high-sensitivity C-reactive protein and sCD40 ligand. Hippocampal subfield estimates were obtained using FreeSurfer. We found a moderate negative association between sTNF-R1 and performance on verbal memory learning and recall tests as measured by the WMS-III Logical Memory after controlling for age, sex and diagnosis. We observed no interaction effect of diagnosis and sTNF-R1 on memory scores. We also found a nominally significant positive association between CVLT learning and hippocampal volumes. The findings suggest a role for immune involvement in memory independent of severe mental disorders and may support the 'bigger is better' hypothesis of hippocampal subfield volumes. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

A readability analysis of elementary-level science textbooks

NASA Astrophysics Data System (ADS)

Trainer, Robyn

Given both the unprecedented attention to the importance of providing children with the best possible science textbooks and the overwhelming evidence that students in the United States are severely lacking the most basic science knowledge, the decline in the number of students pursuing science degrees is alarming. In spite of all the efforts being made, a disparity still exists between (1) the wealth of science information available, (2) the apparent ease of access to scientific information, and (3) the lack of scientific academic progress being made in classrooms across the United States. A literature review was conducted which included the areas of textbook analysis and textbook readability levels, the fields of textbook analysis and readability, and findings from recently published books about textbook readability. The majority of the literature reflected an urgent need for science textbooks to be revised. Based on the information gathered during the literature review, the study examined the readability levels of elementary level science textbooks that were published by six textbook publishers. Results from the study revealed that when used properly, readability formulas provide an objective look at textbooks. After applying these formulas to the selected elementary level science textbooks, it became clear that very few changes were implemented between the most recent previous editions and the current editions. The textbooks remain too difficult for the students using them. The findings from this study will help science textbook publishers and textbook writers see that some changes need to be made in the way their textbooks are written. In order to maintain a competitive edge in the global marketplace, more students need to pursue science. In order for more students to do that, they need to pursue science degrees, but in order for them to pursue science degrees, they need to have a certain degree of confidence and level of interest in the subject matter. For that to happen, science textbooks need to be more inviting, more user-friendly, and more interesting to the readers. This study concludes with recommendations for further research.

Peace Values in Language Textbooks: The Case of "English for Ethiopia Student Textbook"

ERIC Educational Resources Information Center

Gebregeorgis, Mehari Yimulaw

2017-01-01

Textbooks are not only meant to deliver subject knowledge; they are also a medium to convey universal and community-specific values. Aiming to explore the social and emotional development goals of "English for Ethiopia Student Textbook Grade 9," this study reviews the content and activities of the textbook by searching for embedded peace…

Textbook Religion and Lived Religion: A Comparison of the Christian Faith as Expressed in Textbooks and by Young Church Members

ERIC Educational Resources Information Center

Vestøl, Jon Magne

2016-01-01

Drawing on perspectives from sociocultural theory, this article investigates how Christian denominations are represented in Norwegian textbooks of religious education and by young believers. The main finding is that textbooks and young adherents present religion in substantially different ways. While textbooks relate religion to global and…

Readability and Reading Ease Revisited: State-Adopted Science Textbooks.

ERIC Educational Resources Information Center

Chavkin, Laura

1997-01-01

Examines if the reading levels of state-adopted science textbooks at the high-school level are consistent with their intended reader levels. Finds that four of five chemistry textbooks had reading levels beyond high school, while biology textbooks fared better but not as well as the physics and physical science textbooks, which were on grade level…

What Makes a Top-Selling Textbook? Comparing Characteristics of AIS Textbooks

ERIC Educational Resources Information Center

Badua, Frank; Sharifi, Mohsen; Mendez Mediavilla, Francis

2014-01-01

The factors involved in the selection of accounting textbooks are under-investigated, and most of the research is survey-based, largely ignoring the information that could be analyzed by direct inspection of textbook content and its impact on textbook selection. In this study the authors fill this lacuna by deploying content analysis of the…

Identifying and Combating Sexism in EFL Textbooks--With a Case Study into China

ERIC Educational Resources Information Center

Tao, Baiqiang

2008-01-01

This paper explores methodologies of identifying and combating sexism in EFL (English as a Foreign Language) textbooks. The writer of this paper has found out there exists sexism or gender inequality in the Chinese high school EFL textbooks. The writer hopes that future EFL curriculum designers, EFL textbook writers, textbook censors in textbook…

One College's Use of an Open Psychology Textbook

ERIC Educational Resources Information Center

Hilton, John, III; Laman, Carol

2012-01-01

The high cost of textbooks is of concern not only to college students but also to society as a whole. Open textbooks promise the same educational benefits as traditional textbooks; however, their efficacy remains largely untested. We report on a case study about one community college's adoption of a free online psychology textbook. During the fall…

The Adoption of Mark-Up Tools in an Interactive e-Textbook Reader

ERIC Educational Resources Information Center

Van Horne, Sam; Russell, Jae-eun; Schuh, Kathy L.

2016-01-01

Researchers have more often examined whether students prefer using an e-textbook over a paper textbook or whether e-textbooks provide a better resource for learning than paper textbooks, but students' adoption of mark-up tools has remained relatively unexamined. Drawing on the concept of Innovation Diffusion Theory, we used educational data mining…

Evaluation of WorldView Textbooks; Textbooks Taught at a Military University

ERIC Educational Resources Information Center

Khalili, Masoud; Jodai, Hojat

2012-01-01

This paper intends to evaluate the WorldView series textbooks of English learning, which are being taught at an Iranian military university foreign language center. No textbook evaluation had been conducted by the university administration prior to the introduction of the textbooks to the language program. Theorists in the field of ELT textbook…

Representations of the Nature of Scientific Knowledge in Turkish Biology Textbooks

ERIC Educational Resources Information Center

Irez, Serhat

2016-01-01

Considering the impact of textbooks on learning, this study set out to assess representations of the nature of scientific knowledge in Turkish 9th grade biology textbooks. To this end, the ten most commonly used 9th grade biology textbooks were analyzed. A qualitative research approach was utilized and the textbooks were analyzed using…

Islam and the Textbooks. A Report of the American Textbook Council.

ERIC Educational Resources Information Center

Sewall, Gilbert T.

How widely adopted world history textbooks cover Islam and the history of the Middle East is a timely and important subject to explore. In 2001 the American Textbook Council began a comprehensive review of middle school and high school world history textbooks. The Council relied on respected historians and standard sources, influential articles…

INSTRUCTIONAL MANUALS OF BOUNDARY-WORK: PSYCHOLOGY TEXTBOOKS, STUDENT SUBJECTIVITIES, AND DISCIPLINARY HISTORIOGRAPHIES.

PubMed

Flis, Ivan

2016-07-01

This article aims to provide an overview of the historiography of psychology textbooks. In the overview, I identify and describe in detail two strands of writing histories of introductory textbooks of psychology and juxtapose them to provide an integrated historiography of textbooks in psychology. One strand is developed by teachers of psychology-first as a general approach for investigating textbooks in a pedagogical setting, and then later upgraded into a full history of psychology textbooks in America. The other strand follows a more familiar perspective of historians of science and historians of psychology who build on various post-Kuhnian and post-Foucauldian perspectives on textbooks. I make an argument for integrating these two views for a more comprehensive historiography of textbooks in psychology, recasting textbooks as objects of research and sources that are interesting sui generis for historians of psychology in their investigations. © 2016 The Authors. Journal of the History of the Behavioral Sciences Published by Wiley Periodicals, Inc.

Provocative Opinion: Elephantiasis of the Textbook.

ERIC Educational Resources Information Center

Kerber, Robert C.

1988-01-01

Addresses the growing size of college organic chemistry textbooks. Notes that at the current rate of growth, average textbooks will be 1544 pages long in year 2000. Suggests methods to reduce textbook size. (ML)

Genesis of a bad idea

NASA Astrophysics Data System (ADS)

Carlowicz, Michael

According to an article in Business Week (June 10), Macmillan/McGraw-Hill Inc. has agreed to custom-publish a version of its fourth-grade textbook Changing Earth in order to omit a chapter entitled “Birth of Earth.” Parents in the Cobb County, Georgia, school district complained that since the chapter does not include creationism as a theory for the origin of the universe and of Earth, the entire discussion ought to be left out.According to McGraw-Hill, customizing its textbooks is good business. Changing Earth and other such books are designed to allow teachers to build their own programs; the company is willing to customize texts because it does not want to dictate curricula, and it tries to meet demands of school districts. Business Week noted that the theory of evolution still is taught in the sixth and eighth grades, as well as high school, in Cobb County. Changing Earth also contains references to evolution in other chapters besides the one being deleted.

An analysis of science content and representations in introductory college physics textbooks and multimodal learning resources

NASA Astrophysics Data System (ADS)

Donnelly, Suzanne M.

This study features a comparative descriptive analysis of the physics content and representations surrounding the first law of thermodynamics as presented in four widely used introductory college physics textbooks representing each of four physics textbook categories (calculus-based, algebra/trigonometry-based, conceptual, and technical/applied). Introducing and employing a newly developed theoretical framework, multimodal generative learning theory (MGLT), an analysis of the multimodal characteristics of textbook and multimedia representations of physics principles was conducted. The modal affordances of textbook representations were identified, characterized, and compared across the four physics textbook categories in the context of their support of problem-solving. Keywords: college science, science textbooks, multimodal learning theory, thermodynamics, representations

Subfield variations in hippocampal processing-components of a spatial navigation system.

PubMed

Hartley, Matthew; Taylor, Neill; Taylor, John

2005-01-01

The hippocampus is a part of the brain strongly linked to spatial exploration. Within it exist 'place cells' which fire preferentially when an animal is in certain regions of physical space. Recent research has shown that these place cells and their corresponding representations of space behave differently in the CA3 and CA1 subfields of the hippocampus. We review this research and show, by simulation, that these differences can be explained by a combination of known physiological features of the hippocampus and proposed variations in the rate of synaptic plasticity and connection strength between different information pathways. We suggest possible reasons for these differences, namely use of the CA1 cell field for current spatial exploration, and CA3 for longer term spatial memory.

PREVAIL: latest electron optics results

NASA Astrophysics Data System (ADS)

Pfeiffer, Hans C.; Golladay, Steven D.; Gordon, Michael S.; Kendall, Rodney A.; Lieberman, Jon E.; Rockrohr, James D.; Stickel, Werner; Yamaguchi, Takeshi; Okamoto, Kazuya; Umemoto, Takaaki; Shimizu, Hiroyasu; Kojima, Shinichi; Hamashima, Muneki

2002-07-01

The PREVAIL electron optics subsystem developed by IBM has been installed at Nikon's facility in Kumagaya, Japan, for integration into the Nikon commercial EPL stepper. The cornerstone of the electron optics design is the Curvilinear Variable Axis Lens (CVAL) technique originally demonstrated with a proof of concept system. This paper presents the latest experimental results obtained with the electron optical subsystem at Nikon's facility. The results include micrographs illustrating proper CVAL operation through the spatial resolution achieved over the entire optical field of view. They also include data on the most critical issue of the EPL exposure approach: subfield stitching. The methodology of distortion correction will be described and both micrographs and metrology data of stitched subfields will be presented. This paper represents a progress report of the IBM/Nikon alliance activity on EPL.

The Struggle for American Identity: Treatment of Ethnic Groups in United States History Textbooks.

ERIC Educational Resources Information Center

Foster, Stuart J.

1999-01-01

Provides a historical overview of two centuries of change in history textbook writing. Focuses on the social attitudes toward ethnic groups as portrayed in U.S. history textbooks from 1800s-1960s and discusses the conservative themes that are present in U.S. history textbooks. Questions why textbooks adhered to conservative themes. (CMK)

Back to the Future with Textbooks: Using Textbook Passages from the Past to Help Teach Historiography

ERIC Educational Resources Information Center

DeRose, John J.

2009-01-01

Old textbooks are one resource for teaching about the evolution of historical interpretation. Some libraries contain collections of U.S. history textbooks spanning multiple years and some schools even keep older textbooks used in past years. Recently, the author used a book by Kyle Ward entitled "History in the Making: An Absorbing Look at How…

Is Acceptance of E-Textbooks Discipline-Dependent? Comparing Business and Non-Business Student Perceptions

ERIC Educational Resources Information Center

Ciampa, Mark; Thrasher, Evelyn; Marston, Sean; Revels, Mark

2013-01-01

Researchers have looked extensively into the adoption and satisfaction level of academic electronic textbooks (e-textbooks) by students. The majority of research to date has indicated that either students prefer print textbooks to e-textbooks or the results are inconclusive. In this study a survey consisting of questions related to the use of an…

An Economic Analysis of Textbook Pricing and Textbook Markets. ACSFA College Textbook Cost Study Plan Proposal

ERIC Educational Resources Information Center

Koch, James V.

2006-01-01

Between 1986 and 2004, textbook prices rose 186 percent in the United States, or slightly more than six percent per year. Meanwhile, other prices rose only about three percent per year. This paper examines the economic reasons why textbook prices have escalated so briskly and what reasonable alternatives are available that might slow down these…

Searching for New Answers: The Application of Task-Technology Fit to E-Textbook Usage

ERIC Educational Resources Information Center

Gerhart, Natalie; Peak, Daniel A.; Prybutok, Victor R.

2015-01-01

Students have been slow to adopt e-textbooks even though they are often less expensive than traditional textbooks. Prior e-textbook research has focused on adoption behavior, with little research to date on how students perceive e-textbooks fitting their needs. This work builds upon Task-Technology Fit (TTF) and Consumer Acceptance and Use of…

Towards Development of OER Derived Custom-Built Open Textbooks: A Baseline Survey of University Teachers at the University of the South Pacific

ERIC Educational Resources Information Center

Prasad, Deepak; Usagawa, Tsuyoshi

2014-01-01

Textbook prices have soared over the years, with several studies revealing many university students are finding it difficult to afford textbooks. Fortunately, two innovations--open educational resources (OER) and open textbooks--hold the potential to increase textbook affordability. Experts, though, have stated the obvious: that students can save…

Teachers' Views of Mathematics Textbook Series in Flanders: Does it (Not) Matter Which Mathematics Textbook Series Schools Choose?

ERIC Educational Resources Information Center

Van Steenbrugge, H.; Valcke, M.; Desoete, A.

2013-01-01

The debate on the differential effects of mathematics textbook series is a recurrent topic in the research literature. Research results remain inconclusive, pointing to a lack of evidence to decide on the relevance of the selection by schools of a mathematics textbook series. Studies also point to difficulties in comparing textbooks. Recently, in…

Topical Coverage in Introductory Textbooks from the 1980s through the 2000s

ERIC Educational Resources Information Center

Griggs, Richard A.

2014-01-01

To determine how topical coverage in introductory textbooks may have changed from the 1980s to the present, the author examined topic coverage in full-length and brief introductory textbooks from this time period. Because 98% of the teachers use textbooks for the introductory course and the majority do not assign reading beyond the textbook, the…

Why We Won't See Textbooks in Our Disciplinary Rear View Mirror in the Near Future

ERIC Educational Resources Information Center

Rodrigo, Rochelle

2012-01-01

Although not everyone needs textbooks, they still actively serve four audiences within the discipline. The four audiences that benefit from textbooks are students, instructors, the textbook sales force, and the textbook authors themselves. With a growing number of online classes where students have less and less, or even no, face time with their…

A Survey of Professor Acceptance and Use of E-Textbooks in Higher Education

ERIC Educational Resources Information Center

Brown, Randy

2013-01-01

As electronic books (e-books) have continued to gain in popularity, more and more books are becoming available in electronic format. Textbooks are no exception. More and more publishers are making textbooks available in electronic format (e-textbooks). There have been many devices specifically designed to use e-books and e-textbooks with many more…

Closed Hearts, Closed Minds: The Textbook Story of Marriage. A Report to the Nation from the Council on Families.

ERIC Educational Resources Information Center

Glenn, Norval D.; Gallagher, Maggie; Blankenhorn, David, Ed.

This report is a summary opinion of current undergraduate marriage and family textbooks. The report suggests some textbooks are deficient, erroneous, and distorted in information given about marriage. Subheadings include: (1)"Why Textbooks Matter"; (2) "The Textbook Story of Marriage"; (3) "The Dangerous Institution"; (4) "People Who Love Too…

Limited potential of school textbooks to prevent tobacco use among students grade 1–9 across multiple developing countries: a content analysis study

PubMed Central

Saito, Junko; Nonaka, Daisuke; Mizoue, Tetsuya; Kobayashi, Jun; Jayatilleke, Achini C; Shrestha, Sabina; Kikuchi, Kimiyo; Haque, Syed E; Yi, Siyan; Ayi, Irene; Jimba, Masamine

2013-01-01

Objective To evaluate the content of school textbooks as a tool to prevent tobacco use in developing countries. Design Content analysis was used to evaluate if the textbooks incorporated the following five core components recommended by the WHO: (1) consequences of tobacco use; (2) social norms; (3) reasons to use tobacco; (4) social influences and (5) resistance and life skills. Setting Nine developing countries: Bangladesh, Cambodia, Laos, Nepal, Sri Lanka, Benin, Ghana, Niger and Zambia. Textbooks analysed Of 474 textbooks for primary and junior secondary schools in nine developing countries, 41 were selected which contained descriptions about tobacco use prevention. Results Of the 41 textbooks, the consequences of tobacco use component was covered in 30 textbooks (73.2%) and the social norms component was covered in 19 (46.3%). The other three components were described in less than 20% of the textbooks. Conclusions A rather limited number of school textbooks in developing countries contained descriptions of prevention of tobacco use, but they did not fully cover the core components for tobacco use prevention. The chance of tobacco prevention education should be seized by improving the content of school textbooks. PMID:23430601

Limited potential of school textbooks to prevent tobacco use among students grade 1-9 across multiple developing countries: a content analysis study.

PubMed

Saito, Junko; Nonaka, Daisuke; Mizoue, Tetsuya; Kobayashi, Jun; Jayatilleke, Achini C; Shrestha, Sabina; Kikuchi, Kimiyo; Haque, Syed E; Yi, Siyan; Ayi, Irene; Jimba, Masamine

2013-01-01

To evaluate the content of school textbooks as a tool to prevent tobacco use in developing countries. Content analysis was used to evaluate if the textbooks incorporated the following five core components recommended by the WHO: (1) consequences of tobacco use; (2) social norms; (3) reasons to use tobacco; (4) social influences and (5) resistance and life skills. Nine developing countries: Bangladesh, Cambodia, Laos, Nepal, Sri Lanka, Benin, Ghana, Niger and Zambia. TEXTBOOKS ANALYSED: Of 474 textbooks for primary and junior secondary schools in nine developing countries, 41 were selected which contained descriptions about tobacco use prevention. Of the 41 textbooks, the consequences of tobacco use component was covered in 30 textbooks (73.2%) and the social norms component was covered in 19 (46.3%). The other three components were described in less than 20% of the textbooks. A rather limited number of school textbooks in developing countries contained descriptions of prevention of tobacco use, but they did not fully cover the core components for tobacco use prevention. The chance of tobacco prevention education should be seized by improving the content of school textbooks.

Making an Interactive Calculus Textbook.

ERIC Educational Resources Information Center

Larson, Timothy R.

1995-01-01

Presents a case study of the design and production of "Interactive Calculus," an interactive multimedia textbook. Discusses reasons for using multimedia textbooks; what an interactive textbook is; content, organization, graphic design, authoring and composition; and work flow. (AEF)

Comparison of the Impact of Wikipedia, UpToDate, and a Digital Textbook on Short-Term Knowledge Acquisition Among Medical Students: Randomized Controlled Trial of Three Web-Based Resources.

PubMed

Scaffidi, Michael A; Khan, Rishad; Wang, Christopher; Keren, Daniela; Tsui, Cindy; Garg, Ankit; Brar, Simarjeet; Valoo, Kamesha; Bonert, Michael; de Wolff, Jacob F; Heilman, James; Grover, Samir C

2017-10-31

Web-based resources are commonly used by medical students to supplement curricular material. Three commonly used resources are UpToDate (Wolters Kluwer Inc), digital textbooks, and Wikipedia; there are concerns, however, regarding Wikipedia's reliability and accuracy. The aim of this study was to evaluate the impact of Wikipedia use on medical students' short-term knowledge acquisition compared with UpToDate and a digital textbook. This was a prospective, nonblinded, three-arm randomized trial. The study was conducted from April 2014 to December 2016. Preclerkship medical students were recruited from four Canadian medical schools. Convenience sampling was used to recruit participants through word of mouth, social media, and email. Participants must have been enrolled in their first or second year of medical school at a Canadian medical school. After recruitment, participants were randomized to one of the three Web-based resources: Wikipedia, UpToDate, or a digital textbook. During testing, participants first completed a multiple-choice questionnaire (MCQ) of 25 questions emulating a Canadian medical licensing examination. During the MCQ, participants took notes on topics to research. Then, participants researched topics and took written notes using their assigned resource. They completed the same MCQ again while referencing their notes. Participants also rated the importance and availability of five factors pertinent to Web-based resources. The primary outcome measure was knowledge acquisition as measured by posttest scores. The secondary outcome measures were participants' perceptions of importance and availability of each resource factor. A total of 116 medical students were recruited. Analysis of variance of the MCQ scores demonstrated a significant interaction between time and group effects (P<.001, η g 2 =0.03), with the Wikipedia group scoring higher on the MCQ posttest compared with the textbook group (P<.001, d=0.86). Access to hyperlinks, search functions, and open-source editing were rated significantly higher by the Wikipedia group compared with the textbook group (P<.001). Additionally, the Wikipedia group rated open access editing significantly higher than the UpToDate group; expert editing and references were rated significantly higher by the UpToDate group compared with the Wikipedia group (P<.001). Medical students who used Wikipedia had superior short-term knowledge acquisition compared with those who used a digital textbook. Additionally, the Wikipedia group trended toward better posttest performance compared with the UpToDate group, though this difference was not significant. There were no significant differences between the UpToDate group and the digital textbook group. This study challenges the view that Wikipedia should be discouraged among medical students, instead suggesting a potential role in medical education. ©Michael A Scaffidi, Rishad Khan, Christopher Wang, Daniela Keren, Cindy Tsui, Ankit Garg, Simarjeet Brar, Kamesha Valoo, Michael Bonert, Jacob F de Wolff, James Heilman, Samir C Grover. Originally published in JMIR Medical Education (http://mededu.jmir.org), 31.10.2017.

Conceptual Variation or Incoherence? Textbook Discourse on Genes in Six Countries

NASA Astrophysics Data System (ADS)

Gericke, Niklas M.; Hagberg, Mariana; dos Santos, Vanessa Carvalho; Joaquim, Leyla Mariane; El-Hani, Charbel N.

2014-02-01

The aim of this paper is to investigate in a systematic and comparative way previous results of independent studies on the treatment of genes and gene function in high school textbooks from six different countries. We analyze how the conceptual variation within the scientific domain of Genetics regarding gene function models and gene concepts is transformed via the didactic transposition into school science textbooks. The results indicate that a common textbook discourse on genes and their function exist in textbooks from the different countries. The structure of science as represented by conceptual variation and the use of multiple models was present in all the textbooks. However, the existence of conceptual variation and multiple models is implicit in these textbooks, i.e., the phenomenon of conceptual variation and multiple models are not addressed explicitly, nor its consequences and, thus, it ends up introducing conceptual incoherence about the gene concept and its function within the textbooks. We conclude that within the found textbook-discourse ontological aspects of the academic disciplines of genetics and molecular biology were retained, but without their epistemological underpinnings; these are lost in the didactic transposition. These results are of interest since students might have problems reconstructing the correct scientific understanding from the transformed school science knowledge as depicted within the high school textbooks. Implications for textbook writing as well as teaching are discussed in the paper.

Observation of the density and size of cells in hippocampus and vascular lesion in thalamus of GFAP-apoE transgenic mice.

PubMed

Tang, Ke-Feng; Cai, Li; Zhou, Jiang-Ning

2009-08-01

Apolipoprotein E (apoE) is associated with increased risk of age-related diseases, such as Alzheimer's disease (AD) and cerebrovascular disease (CVD). The present study aims to investigate the age-related general morphological changes of the brain in GFAP-apoE transgenic mice, especially the alterations in number and size of hippocampal pyramidal cells and the microvascular lesions in the thalamus. Nine female apoE4/4 mice were divided into 3 groups (n=3 in each group): 3-4 months (young group), 9-10 months (middle-aged group) and 20-21 months (old group). Age-matched apoE3/3 mice were employed as control group (n=3 in each group). The paraffin sections of brain tissue were stained by 2 conventional staining methods, thionin staining and hematoxylin-esion(HE) staining, the former of which was to observe the hippocampal cells, while the latter was used to examine the brain microvasculature. There was no apparent difference in the cortical layer between apoE3/3 and apoE4/4 mice, neither any significant difference in the number of cells in hippocampal CA1-CA3 subfields between apoE3/3 and apoE4/4 mice at various age points (P>0.05). However, the mean size of pyramidal cells in CA1 subfield in apoE3/3 and apoE4/4 mice decreased as mice were getting older (P<0.001). At the age of 20-21 months, this cellular atrophy in apoE4/4 mice was more severe than that in old apoE3/3 mice (P<0.05). Furthermore, microvascular lesion in the thalamus was detected in all the 3 old apoE4/4 mice, at varying degrees (5.24%, 1.41% and 3.97%, respectively), while only one apoE3/3 mouse exhibited microvascular lesion in the thalamus, at a low level (0.85%). The current study suggests that the cell size in hippocampal CA1 subfield decreases with aging, irrespective of apoE genotype. Cellular atrophy in CA1 subfield and the microvascular lesion in the thalamus are both more severe in old apoE4/4 mice as compared with those in age-matched apoE3/3 mice. Doubts still exist on whether the decreased cell size in hippocampal CA1 subfield in old apoE4/4 mice is associated with dysfunction in learning and memory and whether the microvascular lesions indicate a higher risk of stroke in human apoE4 allele mice. To clarify these issues, further investigations are needed.

One-Semester Introductory Economics Textbooks: Echoes and Choices.

ERIC Educational Resources Information Center

Shackelford, Jean

1991-01-01

Reviews 21 one-semester economics textbooks using Kenneth E. Boulding's ideas for introductory textbooks. Lists 240 concepts and topic areas in macroeconomics, microeconomics, public policy, and international economics that may be covered in a textbook. (NL)

What Every Textbook Evaluator Should Know.

ERIC Educational Resources Information Center

Muther, Connie

1985-01-01

Presents information on textbook design and marketing practices, and their consequences for textbook content; recommends that selection committees firmly define the role of the textbook in curriculum, and adapt published materials to their school system's unique requirements. (MCG)

Evaluating Junior Secondary Science Textbook Usage in Australian Schools

NASA Astrophysics Data System (ADS)

McDonald, Christine V.

2016-08-01

A large body of research has drawn attention to the importance of providing engaging learning experiences in junior secondary science classes, in an attempt to attract more students into post-compulsory science courses. The reality of time and resource constraints, and the high proportion of non-specialist science teachers teaching science, has resulted in an overreliance on more transmissive pedagogical tools, such as textbooks. This study sought to evaluate the usage of junior secondary science textbooks in Australian schools. Data were collected via surveys from 486 schools teaching junior secondary (years 7-10), representing all Australian states and territories. Results indicated that most Australian schools use a science textbook in the junior secondary years, and textbooks are used in the majority of science lessons. The most highly cited reason influencing choice of textbook was layout/colour/illustrations, and electronic technologies were found to be the dominant curricula material utilised, in addition to textbooks, in junior secondary science classes. Interestingly, the majority of respondents expressed high levels of satisfaction with their textbooks, although many were keen to stress the subsidiary role of textbooks in the classroom, emphasising the textbook was `one' component of their teaching repertoire. Importantly, respondents were also keen to stress the benefits of textbooks in supporting substitute teachers, beginning teachers, and non-specialist science teachers; in addition to facilitating continuity of programming and staff support in schools with high staff turnover. Implications from this study highlight the need for high quality textbooks to support teaching and learning in Australian junior secondary science classes.

Understanding textbook quality in the USA: How governments distort the market

NASA Astrophysics Data System (ADS)

Oliveira, João Batista

1995-11-01

Textbooks deliver education and shape the daily routines of classrooms. Even in countries where schools enjoy ample and various instructional resources, text-books are the single most important support for teachers and students. It is not surprising, then, that textbooks are a major concern of states, schools, teachers, parents, publishers, and the research community. But textbooks often become a scapegoat for educational evils. In the USA, government regulation, special interest groups, and publishers exert pressure on textbook policies and state and local adoption processes. The result: textbooks are published to conform to a market distorted by government regulation. This paper discusses how their quality is constrained by government and special interest groups that interfere with the natural course of regulations and markets.

Medical students' expectations towards an implementation of a family medicine textbook as a comprehensive app in Germany.

PubMed

Sandholzer, Maximilian; Rurik, Imre; Deutsch, Tobias; Frese, Thomas

2014-10-01

Undergraduate and postgraduate medical education in general practice is complex as a wide medical spectrum needs to be covered. Modern guidelines demand students to be able to recall immense amounts of information relating to the diagnosis and management of clinical problems. With the intent of making a medical textbook digitally available on student mobile devices, preferences of students and potential of the idea was aimed to be researched. A total estimation among fourth year medical students at the Leipzig Medical School was conducted in June 2013. Students were asked to answer a semi-structured self-designed questionnaire regarding their detailed smartphone and app usage as well as their attitude and expectations towards education and practice supporting apps. The response rate was 93.2% (n = 290/311). The majority (69.3%) were female students. The mean age was 24.5 years. Of the respondents, 64.2% owned a smartphone and 22.5% a tablet computer. A total of 32.4% were already using medical apps for the smartphone--mostly drug reference or disease diagnosis and management apps. Regarding their wishes, 68.7% would like or very like to see an app on general practice. The respective means of the most important desired features on a Likert scale reaching from 1 (not important) to 5 (very important) were 4.3 for drug reference information, 4.2 for guidelines for differential diagnosis, 3.9. for medical pictures libraries and 3.9 for physical examination videos. The willingness to pay for a profound app averages at 14.35 Euros (SD = 16.21). Concluding, students clearly demand for an app on general practice. Such an app should ideally be smartphone optimized. Aside of what is usually available in traditional textbooks, multimedia features such as videos on examining methods or a medical picture library are very important to students and may help to bridge the gap between text-based knowledge and practical application. Therefore, authors of medical textbooks need to be aware that the development of an app is no trivial technical translation as raised students expectations demand for multimedia and interactive features as well as comprehensive drug information. Further research should focus on developing concepts to bring together developers and university professionals as well as experienced medical specialists to enable the development of apps that satisfy the demands of undergraduate and postgraduate educational needs.

Neural Correlates of Verbal Episodic Memory and Lexical Retrieval in Logopenic Variant Primary Progressive Aphasia.

PubMed

Win, Khaing T; Pluta, John; Yushkevich, Paul; Irwin, David J; McMillan, Corey T; Rascovsky, Katya; Wolk, David; Grossman, Murray

2017-01-01

Objective: Logopenic variant primary progressive aphasia (lvPPA) is commonly associated with Alzheimer's disease (AD) pathology. But lvPPA patients display different cognitive and anatomical profile from the common clinical AD patients, whose verbal episodic memory is primarily affected. Reports of verbal episodic memory difficulty in lvPPA are inconsistent, and we hypothesized that their lexical retrieval impairment contributes to verbal episodic memory performance and is associated with left middle temporal gyrus atrophy. Methods: We evaluated patients with lvPPA ( n = 12) displaying prominent word-finding and repetition difficulties, and a demographically-matched cohort of clinical Alzheimer's disease (AD, n = 26), and healthy seniors ( n = 16). We assessed lexical retrieval with confrontation naming and verbal episodic memory with delayed free recall. Whole-brain regressions related naming and delayed free recall to gray matter atrophy. Medial temporal lobe (MTL) subfields were examined using high in-plane resolution imaging. Results: lvPPA patients had naming and delayed free recall impairments, but intact recognition memory. In lvPPA, delayed free recall was related to naming; both were associated with left middle temporal gyrus atrophy but not MTL atrophy. Despite cerebrospinal fluid evidence consistent with AD pathology, examination of MTL subfields revealed no atrophy in lvPPA. While AD patients displayed impaired delayed free recall, this deficit did not correlate with naming. Regression analyses related delayed free recall deficits in clinical AD patients to MTL subfield atrophy, and naming to left middle temporal gyrus atrophy. Conclusion: Unlike amnestic AD patients, MTL subfields were not affected in lvPPA patients. Verbal episodic memory deficit observed in lvPPA was unlikely to be due to a hippocampal-mediated mechanism but appeared to be due to poor lexical retrieval. Relative sparing of MTL volume and intact recognition memory are consistent with previous reports of hippocampal-sparing variant cases of AD pathology, where neurofibrillary tangles are disproportionately distributed in cortical areas with relative sparing of the hippocampus. This suggests that AD neuropathology in lvPPA may originate in neuronal networks outside of the MTL, which deviates from the typical Braak staging pattern of spreading pathology in clinical AD.

12-Year Use of a Digital Reference Library (VitalBook) at a U.S. Dental School: Students' and Alumni Perceptions.

PubMed

Spielman, Andrew I; Maas, Elizabeth; Eisenberg, Elise S

2017-10-01

Digital textbooks are being used to reduce production and storage costs of printed copies, enhance usage, and include search capabilities, but the use of digital texts is not universally accepted. In 2001, the New York University College of Dentistry introduced a digital reference library, the VitalBook. Beginning in 2005, the college annually surveyed senior students and, from 2012, also surveyed alumni on their opinions and extent of use of the VitalBook. The aim of this study was to evaluate 12 years of students' perspectives and three years of alumni perspectives on the value of the VitalBook to their dental educational experience. Students were asked how frequently they used the VitalBook, if it was a good investment, if they would use it after graduation, and if they would recommend it to others. Alumni were asked the last three questions. This study reports the results from 4,105 students over 12 years (average response rate 95.3%) and 184 alumni over three years (average response rate 17.4%). The results indicated that students used the VitalBook on average 24% of their study time, but they were split regarding the other questions. The majority opinion in 2005 was negative on all questions. These opinions shifted to become more favorable to a peak in 2010, but declined since then to a more negative overall view of the VitalBook. A split opinion among students continued through 2016, with fewer recommending it although more considered it a good investment with plans to use it after graduation. Alumni mirrored their responses as students. These results suggest that, as more flexible and dynamic digitized reference systems emerge, the use of student-paid traditional digitized textbooks may become an even less favored choice.

Developing Textbook Materials in Uncommon Languages.

ERIC Educational Resources Information Center

Lathrop, Thomas A.

Guidelines are offered for preparing and publishing textbook materials in Portuguese and other uncommonly taught languages. The available options for publishing Portuguese materials include two textbook publishers, three university presses, self-publication, and the Cabrilho Press, which produces language textbooks. Methods for submitting…

Instructor and Student Experiences with Open Textbooks, from the California Open Online Library for Education (Cool4Ed)

ERIC Educational Resources Information Center

Ozdemir, Ozgur; Hendricks, Christina

2017-01-01

Open textbooks are similar to traditional textbooks except that they are free of cost and licensed to allow revision and reuse. Adopting open textbooks for higher education courses is a way to address the growing costs of traditional textbooks that lead some students to be unable to access them, and to allow instructors to tailor the books to…

The Changing Face of War in Textbooks: Depictions of World War II and Vietnam, 1970-2009

ERIC Educational Resources Information Center

Lachmann, Richard; Mitchell, Lacy

2014-01-01

How have U.S. high school textbook depictions of World War II and Vietnam changed since the 1970s? We examined 102 textbooks published from 1970 to 2009 to see how they treated U.S. involvement in World War II and Vietnam. Our content analysis of high school history textbooks finds that U.S. textbooks increasingly focus on the personal experiences…

Digital Game-Based Textbook vs. Traditional Print-Based Textbook: The Effect of Textbook Format on College Students' Engagement with Textbook Content outside of the Classroom

ERIC Educational Resources Information Center

Thomas, Antonio Lamar

2017-01-01

The relatively little amount of time that some college students spend reading their textbooks outside of the classroom presents a significant threat to their academic success. Using Prenksy's (2001) digital game-based learning (DGBL) principles and Astin's student involvement theory as frameworks, the purpose of this true experiment was to…

Women and Economics Textbooks.

ERIC Educational Resources Information Center

Hahn, Carole L.; Blankenship, Glen

1983-01-01

A content analysis of 22 secondary economics textbooks revealed the textbooks to be less sex-biased than the books examined in earlier studies. However, women are still underrepresented in most of the textbooks, and little attention is given to economic realities which women face. (Author/RM)

United States History Textbooks: Cloned Mediocrity.

ERIC Educational Resources Information Center

Siler, Carl R.

1990-01-01

Using content analysis, presents a study of 14 U.S. history textbooks. Analyzes textbook treatment of the Declaration of Independence, the atomic bomb, and the Holocaust. Examines nontextual materials. Finds errors of omission, boring writing styles, and a basic similarity between the textbooks. (RW)

Textbook Development and Selection in Japan and the United States.

ERIC Educational Resources Information Center

Tani, Masaru; And Others

1993-01-01

Reports on a study trip by 13 U.S. social studies educators and publishers to Japan. Compares development, marketing, and selection of textbooks in the United States and Japan. Concludes that both nations should improve textbooks and textbook selection processes. (CFR)

Do textbooks address known learning challenges in area measurement? A comparative analysis

NASA Astrophysics Data System (ADS)

Hong, Dae S.; Choi, Kyong Mi; Runnalls, Cristina; Hwang, Jihyun

2018-02-01

This study compared area lessons from Korean textbooks and US standard-based textbooks to understand differences and similarities among these textbooks, as well as how these textbooks address known learning challenges in area measurement. Several well-known challenges have been identified in previous studies, such as covering, array structure, and linking array structure to area formula. We were interested in knowing if textbooks addressed these issues in their treatments of area measurement and, in doing so, provided students with opportunities to overcome or become familiar with known challenges. The results show that both countries' textbooks demonstrated similar limitations; only few area and area-related lessons are covered and three important learning challenges in area measurement are not covered well, which need to be informed to practicing teachers.

Another seventeenth-century denigration of Gaspare Tagliacozzi.

PubMed

Cosman, B

1978-05-01

Gaspare Tagliacozzi published his carefully documented procedures for nasal reconstruction at the end of the sixteenth century. However, almost all authorities in the succeeding century failed to give him credence. Although his name was widely known, his work became an object of scorn. James Cooke, author of one of the most popular English surgical textbooks of the seventeenth century, in an amusing and previously unnoted reference, adds to this denigration and helps to explain why nasal reconstruction became a subject of satire in England.

[Brief research on the life of LUO Zhao-ju, a modern acupuncturist, and his works].

PubMed

Lin, Yi; Dai, Ming; Peng, Jun-mei

2010-03-01

LUO Zhao-ju's life stories are confirmed and described clearly by widely collecting and systematically analyzing the source materials referring to LUO Zhao-ju. This paper also summarizes his extant sixteen medical books and textbooks and his nineteen papers. LUO Zhao-ju has dedicated his life to combined approach of the theory and clinic of acupuncture and moxibustion, laying equal stress on education and writing, and he has made great contributions to acupuncture and moxibustion in our country.

The MueLu Tutorial

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hu, Jonathan Joseph; Wiesner, Tobias A.; Prokopenko, Andrey

2014-10-01

The MueLu tutorial is written as a hands-on tutorial for MueLu, the next generation multigrid framework in Trilinos. It covers the whole spectrum from absolute beginners’ topics to expert level. Since the focus of this tutorial is on practical and technical aspects of multigrid methods in general and MueLu in particular, the reader is expected to have a basic understanding of multigrid methods and its general underlying concepts. Please refer to multigrid textbooks (e.g. [1]) for the theoretical background.

Geometric Transformations in Middle School Mathematics Textbooks

ERIC Educational Resources Information Center

Zorin, Barbara

2011-01-01

This study analyzed treatment of geometric transformations in presently available middle grades (6, 7, 8) student mathematics textbooks. Fourteen textbooks from four widely used textbook series were evaluated: two mainline publisher series, Pearson (Prentice Hall) and Glencoe (Math Connects); one National Science Foundation (NSF) funded curriculum…

Psychology Ethics in Introductory Psychology Textbooks

ERIC Educational Resources Information Center

Zucchero, Renee' A.

2011-01-01

Previous research revealed that introductory psychology textbooks included limited information about psychology ethics. This study reviewed 48 current introductory psychology textbooks for research and other APA ethics content. These textbooks included slightly more total ethics content and were more thorough in their review of research ethics…

Perspectives on Violence Against Women: A Study of United States Nursing Textbooks.

PubMed

Price-Glynn, Kim; Missari, Stacy

2017-03-01

This study examines conceptualizations of violence against women in U.S. nursing textbooks published from 1995 to 2005. Framing this pivotal decade, the federal Violence Against Women Act (VAWA) was passed and renewed. The American Nurses Association, the National League for Nursing, and the American Association of Colleges of Nursing also recognized violence against women as a health care priority. Sampling 107 generalist nursing textbooks from 1995 to 2005, the current study analyzes textbook terminologies, arguments, and protocols. Textbooks including violence were empirically tested for their application of gender neutral, symmetrical, and asymmetrical theoretical frameworks. Over 40% of generalist textbooks did not mention violence against women. Despite the VAWA in 1994 and broad recognition across national nursing organizations, textbooks did not change with regard to their treatment of violence over the next decade. The frameworks that nursing textbooks use may foster challenges for nurses in recognizing, supporting, and assisting women who are victims/survivors of violence. [J Nurs Educ. 2017;56(3):164-169.]. Copyright 2017, SLACK Incorporated.

The Warm-Hot Intergalactic Medium

NASA Technical Reports Server (NTRS)

Hayes, Jeffrey (Technical Monitor)

2005-01-01

This grant is associated to a 5-year LTSA grant, on "Studying the Largest Reservoir of Baryons in the Universe: The Warm-Hot Intergalactic Medium". The first year of work within this program has been very rich, and has already produced several important results, as detailed in this paper. Table 2 of our original proposal justification, listed the planned year-by-year program, divided into two sub-fields: (A) the study of the z=0 (or Local Group WHIM) system, and (B) the study of the z greater than 0 (i.e- intervening WHIM) systems. For each of the two sub-fields we had planned to analyze, in the first year, a number of archival (Chandra, XMM and FUSE) and new (if observed) sightlines. Moreover, the plan for the z=0 system included the search for new interesting sightlines. We have accomplished all these tasks.

Conceptual Commitments of the LIDA Model of Cognition

NASA Astrophysics Data System (ADS)

Franklin, Stan; Strain, Steve; McCall, Ryan; Baars, Bernard

2013-06-01

Significant debate on fundamental issues remains in the subfields of cognitive science, including perception, memory, attention, action selection, learning, and others. Psychology, neuroscience, and artificial intelligence each contribute alternative and sometimes conflicting perspectives on the supervening problem of artificial general intelligence (AGI). Current efforts toward a broad-based, systems-level model of minds cannot await theoretical convergence in each of the relevant subfields. Such work therefore requires the formulation of tentative hypotheses, based on current knowledge, that serve to connect cognitive functions into a theoretical framework for the study of the mind. We term such hypotheses "conceptual commitments" and describe the hypotheses underlying one such model, the Learning Intelligent Distribution Agent (LIDA) Model. Our intention is to initiate a discussion among AGI researchers about which conceptual commitments are essential, or particularly useful, toward creating AGI agents.

Novel Digital Driving Method Using Dual Scan for Active Matrix Organic Light-Emitting Diode Displays

NASA Astrophysics Data System (ADS)

Jung, Myoung Hoon; Choi, Inho; Chung, Hoon-Ju; Kim, Ohyun

2008-11-01

A new digital driving method has been developed for low-temperature polycrystalline silicon, transistor-driven, active-matrix organic light-emitting diode (AM-OLED) displays by time-ratio gray-scale expression. This driving method effectively increases the emission ratio and the number of subfields by inserting another subfield set into nondisplay periods in the conventional digital driving method. By employing the proposed modified gravity center coding, this method can be used to effectively compensate for dynamic false contour noise. The operation and performance were verified by current measurement and image simulation. The simulation results using eight test images show that the proposed approach improves the average peak signal-to-noise ratio by 2.61 dB, and the emission ratio by 20.5%, compared with the conventional digital driving method.

Anterior-Posterior Cerebral Blood Volume Gradient in Human Subiculum

PubMed Central

Talati, Pratik; Rane, Swati; Kose, Samet; Gore, John; Heckers, Stephan

2014-01-01

The human hippocampal formation is characterized by anterior-posterior gradients of cell density, neurochemistry and hemodynamics. In addition, some functions are associated with specific subfields (subiculum, CA1–4, dentate gyrus) and regions (anterior and posterior). We performed contrast-enhanced, high-resolution T1-weighted 3T steady state (SS) imaging to investigate cerebral blood volume (CBV) gradients of the hippocampal formation. We studied 14 healthy subjects and found significant CBV gradients (anterior > posterior) in the subiculum but not in other hippocampal subfields. Since CBV is a marker of basal metabolism, these results indicate a greater baseline activity in the anterior compared to the posterior subiculum. This gradient might be related to the role of the subiculum as the main outflow station of the hippocampal formation and might have implications for the mechanisms of neuropsychiatric disorders. PMID:24677295

Artificial Intelligence in Surgery: Promises and Perils.

PubMed

Hashimoto, Daniel A; Rosman, Guy; Rus, Daniela; Meireles, Ozanan R

2018-07-01

The aim of this review was to summarize major topics in artificial intelligence (AI), including their applications and limitations in surgery. This paper reviews the key capabilities of AI to help surgeons understand and critically evaluate new AI applications and to contribute to new developments. AI is composed of various subfields that each provide potential solutions to clinical problems. Each of the core subfields of AI reviewed in this piece has also been used in other industries such as the autonomous car, social networks, and deep learning computers. A review of AI papers across computer science, statistics, and medical sources was conducted to identify key concepts and techniques within AI that are driving innovation across industries, including surgery. Limitations and challenges of working with AI were also reviewed. Four main subfields of AI were defined: (1) machine learning, (2) artificial neural networks, (3) natural language processing, and (4) computer vision. Their current and future applications to surgical practice were introduced, including big data analytics and clinical decision support systems. The implications of AI for surgeons and the role of surgeons in advancing the technology to optimize clinical effectiveness were discussed. Surgeons are well positioned to help integrate AI into modern practice. Surgeons should partner with data scientists to capture data across phases of care and to provide clinical context, for AI has the potential to revolutionize the way surgery is taught and practiced with the promise of a future optimized for the highest quality patient care.

Manual segmentation of the fornix, fimbria, and alveus on high-resolution 3T MRI: Application via fully-automated mapping of the human memory circuit white and grey matter in healthy and pathological aging.

PubMed

Amaral, Robert S C; Park, Min Tae M; Devenyi, Gabriel A; Lynn, Vivian; Pipitone, Jon; Winterburn, Julie; Chavez, Sofia; Schira, Mark; Lobaugh, Nancy J; Voineskos, Aristotle N; Pruessner, Jens C; Chakravarty, M Mallar

2018-04-15

Recently, much attention has been focused on the definition and structure of the hippocampus and its subfields, while the projections from the hippocampus have been relatively understudied. Here, we derive a reliable protocol for manual segmentation of hippocampal white matter regions (alveus, fimbria, and fornix) using high-resolution magnetic resonance images that are complementary to our previous definitions of the hippocampal subfields, both of which are freely available at https://github.com/cobralab/atlases. Our segmentation methods demonstrated high inter- and intra-rater reliability, were validated as inputs in automated segmentation, and were used to analyze the trajectory of these regions in both healthy aging (OASIS), and Alzheimer's disease (AD) and mild cognitive impairment (MCI; using ADNI). We observed significant bilateral decreases in the fornix in healthy aging while the alveus and cornu ammonis (CA) 1 were well preserved (all p's<0.006). MCI and AD demonstrated significant decreases in fimbriae and fornices. Many hippocampal subfields exhibited decreased volume in both MCI and AD, yet no significant differences were found between MCI and AD cohorts themselves. Our results suggest a neuroprotective or compensatory role for the alveus and CA1 in healthy aging and suggest that an improved understanding of the volumetric trajectories of these structures is required. Copyright © 2016 Elsevier Inc. All rights reserved.

Individual differences in associative memory among older adults explained by hippocampal subfield structure and function.

PubMed

Carr, Valerie A; Bernstein, Jeffrey D; Favila, Serra E; Rutt, Brian K; Kerchner, Geoffrey A; Wagner, Anthony D

2017-11-07

Older adults experience impairments in episodic memory, ranging from mild to clinically significant. Given the critical role of the medial temporal lobe (MTL) in episodic memory, age-related changes in MTL structure and function may partially account for individual differences in memory. Using ultra-high-field 7T structural MRI and high-resolution 3T functional MRI (hr-fMRI), we evaluated MTL subfield thickness and function in older adults representing a spectrum of cognitive health. Participants performed an associative memory task during hr-fMRI in which they encoded and later retrieved face-name pairs. Motivated by prior research, we hypothesized that differences in performance would be explained by the following: ( i ) entorhinal cortex (ERC) and CA1 apical neuropil layer [CA1-stratum radiatum lacunosum moleculare (SRLM)] thickness, and ( ii ) activity in ERC and the dentate gyrus (DG)/CA3 region. Regression analyses revealed that this combination of factors significantly accounted for variability in memory performance. Among these metrics, CA1-SRLM thickness was positively associated with memory, whereas DG/CA3 retrieval activity was negatively associated with memory. Furthermore, including structural and functional metrics in the same model better accounted for performance than did single-modality models. These results advance the understanding of how independent but converging influences of both MTL subfield structure and function contribute to age-related memory impairment, complementing findings in the rodent and human postmortem literatures.

Obstacle-avoiding navigation system

DOEpatents

Borenstein, Johann; Koren, Yoram; Levine, Simon P.

1991-01-01

A system for guiding an autonomous or semi-autonomous vehicle through a field of operation having obstacles thereon to be avoided employs a memory for containing data which defines an array of grid cells which correspond to respective subfields in the field of operation of the vehicle. Each grid cell in the memory contains a value which is indicative of the likelihood, or probability, that an obstacle is present in the respectively associated subfield. The values in the grid cells are incremented individually in response to each scan of the subfields, and precomputation and use of a look-up table avoids complex trigonometric functions. A further array of grid cells is fixed with respect to the vehicle form a conceptual active window which overlies the incremented grid cells. Thus, when the cells in the active window overly grid cell having values which are indicative of the presence of obstacles, the value therein is used as a multiplier of the precomputed vectorial values. The resulting plurality of vectorial values are summed vectorially in one embodiment of the invention to produce a virtual composite repulsive vector which is then summed vectorially with a target-directed vector for producing a resultant vector for guiding the vehicle. In an alternative embodiment, a plurality of vectors surrounding the vehicle are computed, each having a value corresponding to obstacle density. In such an embodiment, target location information is used to select between alternative directions of travel having low associated obstacle densities.

Normal versus High Tension Glaucoma: A Comparison of Functional and Structural Defects

PubMed Central

Thonginnetra, Oraorn; Greenstein, Vivienne C.; Chu, David; Liebmann, Jeffrey M.; Ritch, Robert; Hood, Donald C.

2009-01-01

Purpose To compare visual field defects obtained with both multifocal visual evoked potential (mfVEP) and Humphrey visual field (HVF) techniques to topographic optic disc measurements in patients with normal tension glaucoma (NTG) and high tension glaucoma (HTG). Methods We studied 32 patients with NTG and 32 with HTG. All patients had reliable 24-2 HVFs with a mean deviation (MD) of −10 dB or better, a glaucomatous optic disc and an abnormal HVF in at least one eye. Multifocal VEPs were obtained from each eye and probability plots created. The mfVEP and HVF probability plots were divided into a central 10-degree (radius) and an outer arcuate subfield in both superior and inferior hemifields. Cluster analyses and counts of abnormal points were performed in each subfield. Optic disc images were obtained with the Heidelberg Retina Tomograph III (HRT III). Eleven stereometric parameters were calculated. Moorfields regression analysis (MRA) and the glaucoma probability score (GPS) were performed. Results There were no significant differences in MD and PSD values between NTG and HTG eyes. However, NTG eyes had a higher percentage of abnormal test points and clusters of abnormal points in the central subfields on both mfVEP and HVF than HTG eyes. For HRT III, there were no significant differences in the 11 stereometric parameters or in the MRA and GPS analyses of the optic disc images. Conclusions The visual field data suggest more localized and central defects for NTG than HTG. PMID:19223786

Anatomical verification and designation of the superficial layer of the temporalis muscle.

PubMed

Lee, Ju-Young; Kim, Jeong-Nam; Kim, Soon-Heum; Choi, Hyun-Gon; Hu, Kyung-Seok; Kim, Hee-Jin; Song, Wu-Chul; Koh, Ki-Seok

2012-03-01

The temporalis muscle, which is one of the masticatory muscles, enables elevation and retraction of the mandible. Direct injury to the temporalis muscle, facial nerve, or temporal fat pad during cranial-base surgery can cause temporal hollowing. The temporalis muscle is currently described in almost all atlases and textbooks as comprising a single layer. In this study, a superficial layer of the temporalis muscle is described, clarifying the anatomy of this muscle. Twenty heads of adult cadavers were dissected. The gross anatomy of the temporalis muscle was examined after removing the skin, subcutaneous tissue, superficial temporal fascia, and deep temporal fascia. The superficial layer of the temporalis muscle was clearly distinguishable from the deep layer. The superficial layer originated from the same region as the deep layer, and the muscle fibers of the two layers were intermingled in the superior part of the muscle. The deep layer of the temporalis muscle, which is referred to in textbooks and atlases simply as the temporalis muscle, was exposed after removing the superficial layer. The existence of this superficial layer was confirmed herein both histologically and by magnetic resonance imaging. Henceforth, the superficial layer of the temporalis muscle must be included in descriptions of the temporalis muscle in anatomy textbooks and atlases. The findings of this study are important not only from the perspective of simply acquiring correct anatomical knowledge, but also from the surgical perspective in preventing temporal hollowing during related surgical procedures. Copyright © 2011 Wiley-Liss, Inc.

Faculty Views on eTextbooks: A Narrative Study

ERIC Educational Resources Information Center

Bossaller, Jenny; Kammer, Jenna

2014-01-01

eTextbooks are both texts and tools. They provide opportunities for textbook companies to expand their services. Some large textbook companies are offering extensive educational technology products and services along with texts. These etexts, integrated into the Learning Management System (LMS), give instructors opportunities to use integrated…

Principles of Economics Textbooks: Innovation and Product Differentiation--A Response.

ERIC Educational Resources Information Center

Sichel, Werner

1988-01-01

Focusing on areas of contention, the author responds to "Principles of Economics Textbooks: Innovation and Product Differentiation" by Stiglitz. Contends that Stiglitz's description of principles textbooks is insufficient, states that the textbook market is more oligopolistic than monopolistic, and cautions writers against deleting parts…

Textbooks: What's at Stake?

ERIC Educational Resources Information Center

Focus in Change, 1992

1992-01-01

Textbooks have an enormous influence on the curriculum of schools across the nation. Many issues are taken into consideration when selecting textbooks. Textbooks that present students with a multicultural curriculum are often at the center of debate among school administrators. This journal presents a series of articles based on interviews with…

The Purpose of State Level Textbook Adoption: What Does the Legislation Reveal?

ERIC Educational Resources Information Center

Tulley, Michael A.; Farr, Roger

1985-01-01

A content analysis of textbook adoption statutes of 22 states was undertaken to gain insight into the reasons behind state textbook adoption. Findings indicate the intent of state-level textbook adoption may be to control marketing practices of the publishing industry. (DF)

Multidirectional War Narratives in History Textbooks

ERIC Educational Resources Information Center

van der Vlies, Tina

2016-01-01

This article aims to contribute to the field of textbook research by exploring a new approach in textbook analysis. Inspired by Michael Rothberg's concept of multidirectional memory, this article examines multidirectional narratives in history textbooks: narratives that combine different histories, places and times in a productive way. They…

A Study of Four Textbook Distribution Models

ERIC Educational Resources Information Center

Graydon, Benjamin; Urbach-Buholz, Blake; Kohen, Cheryl

2011-01-01

Textbooks too often hinder rather than help students because of their prohibitively expensive prices. Colleges and universities facing intense pressure to lower education expenses while increasing access, retention, and achievement now find addressing the textbook problem more and more urgent. Used textbook sales have grown dramatically over the…

[Hygienic Assesment of Educational Texts: Methodical Approaches and Evaluation of Difficulties for Children of Secondary Textbooks].

PubMed

Kuchma, V R; Tkachuk, E A

2015-01-01

The understandability and readability of the text are significant indicators of evaluation of textbooks. The aim of the study - rationale of improving the readability and understandability of textbooks. 60 modern textbooks for 5-11th classes on History, Physics, Biology and 23 textbooks of 1960-1980's edition. Flesch index was used to assess the readability, Fogh index - to evaluate understandability. The readability and understandability of texts in textbooks of 1960-1980's and modern editions have no differences and show the same complexity of old and modern textbooks for students. The indicator of understandability of textbooks for primary classes corresponds to age norm and is 4.4±0.2 points. The indicator of readability for these books is less age norm and is 53.8±2.9 points, which increases the physiological cost of educational activities of children of primary school age. Children's readability and understandability of school textbooks are a significant factor of intensity of training activities and can be objectively assessed by Flesch and Fogh indices, that it is appropriate for an objective hygienic assessment of the tension of the educational activities for children. The main direction of optimization of the tension of educational activity is to reduce the intellectual and emotional loads in children by increasing the easiness of reading textbooks due to their compliance with the age peculiarities of students.

Evaluation of Pyrrolidonyl Arylamidase Activity in Staphylococcus delphini.

PubMed

Compton, Samantha T; Kania, Stephen A; Robertson, Amy E; Lawhon, Sara D; Jenkins, Stephen G; Westblade, Lars F; Bemis, David A

2017-03-01

Clinical reference textbooks lack data for pyrrolidonyl arylamidase (PYR) activity in Staphylococcus delphini This study evaluated PYR activities of 21 S. delphini strains by reference broth, rapid disc, and rapid slide methods. Species and subgroup identifications were confirmed by nucleic acid-based methods and included nine group A and 12 group B strains. Testing by rapid PYR methods with products from four manufacturers was performed at two testing locations, and, with the exception of one strain tested at one location using reagents from one manufacturer, each S. delphini strain tested positive for PYR activity. Therefore, PYR may be a useful single-test adjunct for distinguishing Staphylococcus aureus from S. delphini and other members of the Staphylococcus intermedius group. Copyright © 2017 American Society for Microbiology.

[Guidelines on urolithiasis: an outline and effective use of the revised version].

PubMed

Kohri, Kenjiro; Suzuki, Koji

2012-12-01

Progress has been made in the diagnosis and treatment of urolithiasis over the last 10 years, after the first version of the Guidelines on Urolithiasis was published in December 2002. Considering such a situation, the revised version is due for publication soon. At this symposium, 3 persons who were engaged in the revision of the guidelines presented its digest. The revised version is characterized by the adoption of a "Frequently asked questions style", aiming to facilitate its usage as a reference book or dictionary readers can refer to when a question is raised in practice. It may be possible to further promote the medical treatment of urolithiasis by effectively using this in combination with the relatively textbook-like first version.

Learning English with Electronic Textbooks on Tablet PCs

ERIC Educational Resources Information Center

Lin, Chih-cheng

2017-01-01

Previous studies on electronic textbooks were all survey studies of college students in the U.S.A. Their main findings revealed that using electronic textbooks and using print textbooks showed no statistical differences in learning achievements. As mobile devices became popular in classrooms, the present study was intended to confirm the…

What Produces a History Textbook?

ERIC Educational Resources Information Center

Chughtai, Mariam

2015-01-01

In this dissertation, I undertake a sequential analysis of an elaborate system of forces that contribute to the production of history textbooks in Pakistan. I review longitudinal series of data on education policies and history textbooks from 1938-2012, and examine the decision-making processes, which inform said policies and textbooks, at the…

The Educational Design of Textbooks: A Text for Being Interdisciplinary

ERIC Educational Resources Information Center

Golding, Clinton

2014-01-01

This paper provides insights into both the educational design of textbooks and interdisciplinary education. The author introduces two educational principles for textbook design--instructional alignment and balancing diversity and meaningful guidance for readers--and applies them to writing his own textbook chapter for being interdisciplinary. The…

Understanding Linear Function: A Comparison of Selected Textbooks from England and Shanghai

ERIC Educational Resources Information Center

Wang, Yuqian; Barmby, Patrick; Bolden, David

2017-01-01

This study describes a comparison of how worked examples in selected textbooks from England and Shanghai presented possible learning trajectories towards understanding linear function. Six selected English textbooks and one Shanghai compulsory textbook were analysed with regards to the understanding required for pure mathematics knowledge in…

Visuals in Perspective: An Analysis of U.S. History Textbooks.

ERIC Educational Resources Information Center

Bliss, Traci

1990-01-01

Traces the changes in the visuals used in U.S. history textbooks since the 1900s, concentrating on contemporary texts. Provides questions educators can use in assessing the educational value of textbook visuals. Critiques current textbook visuals, and suggests ways that they enhance understanding of educational information. (RW)

Should Geography Educators Adopt Electronic Textbooks?

ERIC Educational Resources Information Center

Romig, Kevin

2017-01-01

Significant changes in textbook publishing are at college instructors' door. Textbook representatives are directed to mesmerize potential clients with eye-catching displays and statements about digital literacy of the next generation of college students. Based on a one-year pilot study, in 2014-2015, of an electronic textbook, this commentary…

"World Religions" in Introductory Sociology Textbooks

ERIC Educational Resources Information Center

Carroll, Michael P.

2017-01-01

A section on "world religions" (WRs) is now routinely included in the religion chapters of introductory sociology textbooks. Looking carefully at these WR sections, however, two things seem puzzling. The first is that the criteria for defining a WR varies considerably from textbook to textbook; the second is that these WRs sections…

Evaluation of Two ESP Textbooks

ERIC Educational Resources Information Center

Al Fraidan, Abdullah

2012-01-01

This paper evaluated two ESP textbooks using the evaluation of McDonough and Shaw (2003) based on external and internal evaluation. The first textbook is "Business Objectives" (1996) by Vicki Hollett, and the second textbook is "Business Studies, Second Edition" (2002) by Alain Anderton. To avoid repetition, I will use BO and…

Australia in German Geography Textbooks for Middle Schools

ERIC Educational Resources Information Center

Hamann, Berta

2007-01-01

German Geography textbooks are structured using the principle of "Systematic Geography based on a regional example" that is predominant in Germany. Compared to other macroregions such as Europe, North America, Africa, or Asia, however, Australia is presented less frequently in school textbooks. Those textbooks which deal with Australia…

The High School Economics Text: An Examination of Priorities and Needs.

ERIC Educational Resources Information Center

Radner, Barbara

1990-01-01

Analyzes high school economics textbooks through an examination of the questions that textbooks traditionally address about economic production: What, how much, and how will something be produced, and who gets the product? Considers teachers' relationships to economic textbooks and courses. Concludes that textbooks should be more relevant to…

Reasoning and Proving Opportunities in Textbooks: A Comparative Analysis

ERIC Educational Resources Information Center

Hong, Dae S.; Choi, Kyong Mi

2018-01-01

In this study, we analyzed and compared reasoning and proving opportunities in geometry lessons from American standard-based textbooks and Korean textbooks to understand how these textbooks provide student opportunities to engage in reasoning and proving activities. Overall, around 40% of exercise problems in Core Plus Mathematics Project (CPMP)…

Manufacturing Visions of Society and History in Textbooks.

ERIC Educational Resources Information Center

Perlmutter, David D.

1997-01-01

Finds that the secondary-school textbook vision of society is homogenized and sanitized to reduce the risk of controversy. Reveals three domains of control that influence textbook visual content: industrial (how the image world of a textbook is created); commercial (marketing pressures); and social (interest groups that influence the visual…

Development of Open Textbooks Learning Analytics System

ERIC Educational Resources Information Center

Prasad, Deepak; Totaram, Rajneel; Usagawa, Tsuyoshi

2016-01-01

Textbook costs have skyrocketed in recent years, putting them beyond the reach of many students, but there are options which can mitigate this problem. Open textbooks, an open educational resource, have proven capable of making textbooks affordable to students. There have been few educational development as promising as the development of open…

Representation of Scientific Methodology in Secondary Science Textbooks

ERIC Educational Resources Information Center

Binns, Ian C.

2009-01-01

The purpose of this investigation was to assess the representation of scientific methodology in secondary science textbooks. More specifically, this study looked at how textbooks introduced scientific methodology and to what degree the examples from the rest of the textbook, the investigations, and the images were consistent with the text's…

Narrative in Essays: A Challenge of Textbook Truisms.

ERIC Educational Resources Information Center

Hesse, Douglas

Most textbooks, ignoring current narrative theory, fail to explain a large number of published essays containing narrative. To challenge textbook definitions of narratives, three points should be made: (1) a clear distinction should be recognized between narratives making points and narratives proving points, (2) the textbook equating of…