Residual standard deviation: Validation of a new measure of dual-task cost in below-knee prosthesis users.

PubMed

Howard, Charla L; Wallace, Chris; Abbas, James; Stokic, Dobrivoje S

2017-01-01

We developed and evaluated properties of a new measure of variability in stride length and cadence, termed residual standard deviation (RSD). To calculate RSD, stride length and cadence are regressed against velocity to derive the best fit line from which the variability (SD) of the distance between the actual and predicted data points is calculated. We examined construct, concurrent, and discriminative validity of RSD using dual-task paradigm in 14 below-knee prosthesis users and 13 age- and education-matched controls. Subjects walked first over an electronic walkway while performing separately a serial subtraction and backwards spelling task, and then at self-selected slow, normal, and fast speeds used to derive the best fit line for stride length and cadence against velocity. Construct validity was demonstrated by significantly greater increase in RSD during dual-task gait in prosthesis users than controls (group-by-condition interaction, stride length p=0.0006, cadence p=0.009). Concurrent validity was established against coefficient of variation (CV) by moderate-to-high correlations (r=0.50-0.87) between dual-task cost RSD and dual-task cost CV for both stride length and cadence in prosthesis users and controls. Discriminative validity was documented by the ability of dual-task cost calculated from RSD to effectively differentiate prosthesis users from controls (area under the receiver operating characteristic curve, stride length 0.863, p=0.001, cadence 0.808, p=0.007), which was better than the ability of dual-task cost CV (0.692, 0.648, respectively, not significant). These results validate RSD as a new measure of variability in below-knee prosthesis users. Future studies should include larger cohorts and other populations to ascertain its generalizability. Copyright © 2016 Elsevier B.V. All rights reserved.

47 CFR 69.152 - End user common line for price cap local exchange carriers.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 3 2010-10-01 2010-10-01 false End user common line for price cap local...) COMMON CARRIER SERVICES (CONTINUED) ACCESS CHARGES Computation of Charges for Price Cap Local Exchange Carriers § 69.152 End user common line for price cap local exchange carriers. (a) A charge that is...

Wearable Notification via Dissemination Service in a Pervasive Computing Environment

DTIC Science & Technology

2015-09-01

context, state, and environment in a manner that would be transparent to a Soldier’s common operations. 15. SUBJECT TERMS pervasive computing, Android ...of user context shifts, i.e., changes in the user’s position, history , workflow, or resource interests. If the PCE is described as a 2-component...convenient viewing on the Glass’s screen just above the line of sight. All of the software developed uses Google’s Android open-source software stack

Preliminary evidence of hippocampal damage in chronic users of ecstasy.

PubMed

den Hollander, Bjørnar; Schouw, Marieke; Groot, Paul; Huisman, Henk; Caan, Matthan; Barkhof, Frederik; Reneman, Liesbeth

2012-01-01

Various studies have shown that ecstasy (3,4-methylenedioxymethamphetamine) users display significant memory impairments, whereas their performance on other cognitive tests is generally normal. The hippocampus plays an essential role in short-term memory. There are, however, no structural human data on the effects of ecstasy on the hippocampus. The objective of this study was to investigate whether the hippocampal volume of chronic ecstasy users is reduced when compared with healthy polydrug-using controls, as an indicator of hippocampal damage. The hippocampus was manually outlined in volumetric MRI scans in 10 male ecstasy users (mean age 25.4 years) and seven healthy age- and gender-matched control subjects (21.3 years). Other than the use of ecstasy, there were no statistically significant differences between both groups in exposure to other drugs of abuse and alcohol. The ecstasy users were on average drug-free for more than 2 months and had used on average 281 tablets over the past six and a half years. The hippocampal volume in the ecstasy using group was on average 10.5% smaller than the hippocampal volume in the control group (p=0.032). These data provide preliminary evidence that ecstasy users may be prone to incurring hippocampal damage, in line with previous reports of acute hippocampal sclerosis and subsequent atrophy in chronic users of this drug.

Northwestern University Flexible Subischial Vacuum Socket for persons with transfemoral amputation: Part 2 Description and Preliminary evaluation.

PubMed

Fatone, Stefania; Caldwell, Ryan

2017-06-01

Current transfemoral prosthetic sockets are problematic as they restrict function, lack comfort, and cause residual limb problems. Development of a subischial socket with lower proximal trim lines is an appealing way to address this problem and may contribute to improving quality of life of persons with transfemoral amputation. The purpose of this study was to illustrate the use of a new subischial socket in two subjects. Case series. Two unilateral transfemoral prosthesis users participated in preliminary socket evaluations comparing functional performance of the new subischial socket to ischial containment sockets. Testing included gait analysis, socket comfort score, and performance-based clinical outcome measures (Rapid-Sit-To-Stand, Four-Square-Step-Test, and Agility T-Test). For both subjects, comfort was better in the subischial socket, while gait and clinical outcomes were generally comparable between sockets. While these evaluations are promising regarding the ability to function in this new socket design, more definitive evaluation is needed. Clinical relevance Using gait analysis, socket comfort score and performance-based outcome measures, use of the Northwestern University Flexible Subischial Vaccum Socket was evaluated in two transfemoral prosthesis users. Socket comfort improved for both subjects with comparable function compared to ischial containment sockets.

Understanding Infusion Pumps.

PubMed

Mandel, Jeff E

2018-04-01

Infusion systems are complicated electromechanical systems that are used to deliver anesthetic drugs with moderate precision. Four types of systems are described-gravity feed, in-line piston, peristaltic, and syringe. These systems are subject to a number of failure modes-occlusion, disconnection, siphoning, infiltration, and air bubbles. The relative advantages of the various systems and some of the monitoring capabilities are discussed. A brief example of the use of an infusion system during anesthetic induction is presented. With understanding of the functioning of these systems, users may develop greater comfort.

Articulating Support for Horizontal Resistive Exercise

NASA Technical Reports Server (NTRS)

Gundo, Daniel; Schaffner, Grant; Bentley, Jason; Loehr, James A.

2005-01-01

A versatile mechanical device provides support for a user engaged in any of a variety of resistive exercises in a substantially horizontal orientation. The unique features and versatility of the device promise to be useful in bedrest studies, rehabilitation, and specialized strength training. The device affords a capability for selectively loading and unloading of portions of the user s body through its support mechanisms, so that specific parts of the body can be trained with little or no effect on other parts that may be disabled or in the process of recovery from injury. Thus, the device is ideal for rehabilitation exercise programs prescribed by physicians and physical therapists. The capability for selective loading and support also offers potential benefits to strength and conditioning trainers and athletes who wish to selectively strengthen selected parts. The principal innovative aspect of the device is that it supports the subject s weight while enabling the subject, lying substantially horizontally, to perform an exercise that closely approximates a full standing squat. The device includes mechanisms that support the subject in such a way that the hips are free to translate both horizontally and vertically and are free to rotate about the line connecting the hips. At the same time, the shoulders are free to translate horizontally while the upper back is free to rotate about the line connecting the shoulders. Among the mechanisms for hip motion and support is a counterbalance that offsets the weight of the subject as the subject s pelvis translates horizontally and vertically and rotates the pelvis about the line connecting the hips. The counterbalance is connected to a pelvic support system that allows these pelvic movements. The subject is also supported at the shoulder by a mechanism that can tilt to provide continuous support of the upper back while allowing the rotation required for arching the back as the pelvis is displaced. The shoulder support also affords a capability for horizontal motion, and acts as the point of attachment of a load that is provided for squat and heel-raise exercises. The device is compatible with any resistive-exercise machine that provides bilateral loading via a moving cable or other mechanical linkage. The hip-translation and shoulder-translation and -rotation degrees of freedom of the supports can be locked individually or in combination in order to support the subject as necessary for exercises other than the standing squat. If necessary, for such exercises, the load can be applied directly to the subject by use of various attachments. In addition to the aforementioned heel raise, such exercises include the upright row, leg press, curls, extension of the triceps, front raise, lateral raise, and rear raise.

A navigation system for the visually impaired an intelligent white cane.

PubMed

Fukasawa, A Jin; Magatani, Kazusihge

2012-01-01

In this paper, we describe about a developed navigation system that supports the independent walking of the visually impaired in the indoor space. Our developed instrument consists of a navigation system and a map information system. These systems are installed on a white cane. Our navigation system can follow a colored navigation line that is set on the floor. In this system, a color sensor installed on the tip of a white cane, this sensor senses a color of navigation line and the system informs the visually impaired that he/she is walking along the navigation line by vibration. This color recognition system is controlled by a one-chip microprocessor. RFID tags and a receiver for these tags are used in the map information system. RFID tags are set on the colored navigation line. An antenna for RFID tags and a tag receiver are also installed on a white cane. The receiver receives the area information as a tag-number and notifies map information to the user by mp3 formatted pre-recorded voice. And now, we developed the direction identification technique. Using this technique, we can detect a user's walking direction. A triaxiality acceleration sensor is used in this system. Three normal subjects who were blindfolded with an eye mask were tested with our developed navigation system. All of them were able to walk along the navigation line perfectly. We think that the performance of the system is good. Therefore, our system will be extremely valuable in supporting the activities of the visually impaired.

On-Line Database of Vibration-Based Damage Detection Experiments

NASA Technical Reports Server (NTRS)

Pappa, Richard S.; Doebling, Scott W.; Kholwad, Tina D.

2000-01-01

This paper describes a new, on-line bibliographic database of vibration-based damage detection experiments. Publications in the database discuss experiments conducted on actual structures as well as those conducted with simulated data. The database can be searched and sorted in many ways, and it provides photographs of test structures when available. It currently contains 100 publications, which is estimated to be about 5-10% of the number of papers written to date on this subject. Additional entries are forthcoming. This database is available for public use on the Internet at the following address: http://sdbpappa-mac.larc.nasa.gov. Click on the link named "dd_experiments.fp3" and then type "guest" as the password. No user name is required.

User’s Manual for the Modular Analysis-Package Libraries ANAPAC and TRANL

DTIC Science & Technology

1977-09-01

number) Computer software Fourier transforms Computer software library Interpolation software Digitized data...disregarded to give the user a simplified plot. (b) The last digit of ISPACE determines the type of line to be drawn, provided KODE is not...negative. If the last digit of ISPACE is 0 a solid line is drawn 1 a dashed line is drawn - - - 2 a dotted line is drawn .... 3 a dash-dot line is

Northwestern University Flexible Subischial Vacuum Socket for persons with transfemoral amputation: Part 2 Description and Preliminary evaluation

PubMed Central

Fatone, Stefania; Caldwell, Ryan

2017-01-01

Background: Current transfemoral prosthetic sockets are problematic as they restrict function, lack comfort, and cause residual limb problems. Development of a subischial socket with lower proximal trim lines is an appealing way to address this problem and may contribute to improving quality of life of persons with transfemoral amputation. Objectives: The purpose of this study was to illustrate the use of a new subischial socket in two subjects. Study design: Case series. Methods: Two unilateral transfemoral prosthesis users participated in preliminary socket evaluations comparing functional performance of the new subischial socket to ischial containment sockets. Testing included gait analysis, socket comfort score, and performance-based clinical outcome measures (Rapid-Sit-To-Stand, Four-Square-Step-Test, and Agility T-Test). Results: For both subjects, comfort was better in the subischial socket, while gait and clinical outcomes were generally comparable between sockets. Conclusion: While these evaluations are promising regarding the ability to function in this new socket design, more definitive evaluation is needed. Clinical relevance Using gait analysis, socket comfort score and performance-based outcome measures, use of the Northwestern University Flexible Subischial Vaccum Socket was evaluated in two transfemoral prosthesis users. Socket comfort improved for both subjects with comparable function compared to ischial containment sockets. PMID:28132589

The User-Subjective Approach to Personal Information Management Systems.

ERIC Educational Resources Information Center

Bergman, Ofer; Beyth-Marom, Ruth; Nachmias, Rafi

2003-01-01

Explains personal information management (PIM) systems and suggests a user-subjective approach to PIM system design. Advocates that PIM systems relate to the subjective value-added attributes that the user gives the stored data so that the user can find information again, recall it when needed, and use it effectively in the next interaction.…

Comparative analysis on flexibility requirements of typical Cryogenic Transfer lines

NASA Astrophysics Data System (ADS)

Jadon, Mohit; Kumar, Uday; Choukekar, Ketan; Shah, Nitin; Sarkar, Biswanath

2017-04-01

The cryogenic systems and their applications; primarily in large Fusion devices, utilize multiple cryogen transfer lines of various sizes and complexities to transfer cryogenic fluids from plant to the various user/ applications. These transfer lines are composed of various critical sections i.e. tee section, elbows, flexible components etc. The mechanical sustainability (under failure circumstances) of these transfer lines are primary requirement for safe operation of the system and applications. The transfer lines need to be designed for multiple design constraints conditions like line layout, support locations and space restrictions. The transfer lines are subjected to single load and multiple load combinations, such as operational loads, seismic loads, leak in insulation vacuum loads etc. [1]. The analytical calculations and flexibility analysis using professional software are performed for the typical transfer lines without any flexible component, the results were analysed for functional and mechanical load conditions. The failure modes were identified along the critical sections. The same transfer line was then refurbished with the flexible components and analysed for failure modes. The flexible components provide additional flexibility to the transfer line system and make it safe. The results obtained from the analytical calculations were compared with those obtained from the flexibility analysis software calculations. The optimization of the flexible component’s size and selection was performed and components were selected to meet the design requirements as per code.

Chronic effects of cannabis use on the auditory mismatch negativity.

PubMed

Greenwood, Lisa-Marie; Broyd, Samantha J; Croft, Rodney; Todd, Juanita; Michie, Patricia T; Johnstone, Stuart; Murray, Robin; Solowij, Nadia

2014-03-15

Cannabis use is associated with the development of psychotic symptoms and increased risk for schizophrenia. The mismatch negativity (MMN) is a brain event-related potential marker of change detection thought to index glutamatergic N-methyl-D-aspartate receptor-mediated neurotransmission, which is known to be deficient in schizophrenia. This study examined auditory MMN in otherwise healthy chronic cannabis users compared with nonuser control subjects. Forty-two chronic cannabis users and 44 nonuser healthy control subjects completed a multi-feature MMN paradigm, which included duration, frequency, and intensity deviants (deviants 6%; standards 82%). The MMN was compared between users and control subjects as well as between long- and short-term users and age- and gender-matched control subjects. Associations between MMN, cannabis use measures, and symptoms were examined. The MMN amplitude was significantly reduced to frequency but not duration or intensity deviants in overall cannabis users relative to control subjects. Frequency MMN was similarly attenuated in short- and long-term users relative to control subjects. Long-term users also exhibited reduced duration MMN relative to control subjects and short-term users and this was correlated with increased duration of exposure to cannabis and increased psychotic-like experiences during intoxication. In short-term users, a younger age of onset of regular cannabis use and greater frequency of use were associated with greater psychotic-like experiences and symptomatic distress. These results suggest impaired sensory memory that might reflect N-methyl-D-aspartate receptor dysfunction in chronic cannabis users. The pattern of MMN alterations in cannabis users differed from that typically observed in patients with schizophrenia, indicating overlapping but distinct underlying pathology. Copyright © 2014 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

Collaborative Aerial-Drawing System for Supporting Co-Creative Communication

NASA Astrophysics Data System (ADS)

Osaki, Akihiro; Taniguchi, Hiroyuki; Miwa, Yoshiyuki

This paper describes the collaborative augmented reality (AR) system with which multiple users can handwrite 3D lines in the air simultaneously and manipulate the lines directly in the real world. In addition, we propose a new technique for co-creative communication utilizing the 3D drawing activity. Up to now, the various 3D user interfaces have been proposed. Although most of them aim to solve the specific problems in the virtual environments, the possibility of the 3D drawing expression has not been explored yet. Accordingly, we paid special attention to the interaction with the real objects in daily life, and considered to manipulate real objects and 3D lines without any distinctions by the same action. The developed AR system consists of a stereoscopic head-mounted display, a drawing tool, 6DOF sensors measuring three-dimensional position and Euler angles, and the 3D user interface, which enables to push, grasp and pitch 3D lines directly by use of the drawing tool. Additionally users can pick up desired color from either a landscape or a virtual line through the direct interaction with this tool. For sharing 3D lines among multiple users at the same place, the distributed-type AR system has been developed that mutually sends and receives drawn data between systems. With the developed system, users can proceed to design jointly in the real space through arranging each 3D drawing by direct manipulation. Moreover, a new application to the entertainment has become possible to play sports like catch, fencing match, or the like.

Randomized Controlled Ethanol Cookstove Intervention and Blood Pressure in Pregnant Nigerian Women.

PubMed

Alexander, Donee; Northcross, Amanda; Wilson, Nathaniel; Dutta, Anindita; Pandya, Rishi; Ibigbami, Tope; Adu, Damilola; Olamijulo, John; Morhason-Bello, Oludare; Karrison, Theodore; Ojengbede, Oladosu; Olopade, Christopher O

2017-06-15

Hypertension during pregnancy is a leading cause of maternal mortality. Exposure to household air pollution elevates blood pressure (BP). To investigate the ability of a clean cookstove intervention to lower BP during pregnancy. We conducted a randomized controlled trial in Nigeria. Pregnant women cooking with kerosene or firewood were randomly assigned to an ethanol arm (n = 162) or a control arm (n = 162). BP measurements were taken during six antenatal visits. In the primary analysis, we compared ethanol users with control subjects. In subgroup analyses, we compared baseline kerosene users assigned to the intervention with kerosene control subjects and compared baseline firewood users assigned to ethanol with firewood control subjects. The change in diastolic blood pressure (DBP) over time was significantly different between ethanol users and control subjects (P = 0.040); systolic blood pressure (SBP) did not differ (P = 0.86). In subgroup analyses, there was no significant intervention effect for SBP; a significant difference for DBP (P = 0.031) existed among preintervention kerosene users. At the last visit, mean DBP was 2.8 mm Hg higher in control subjects than in ethanol users (3.6 mm Hg greater in control subjects than in ethanol users among preintervention kerosene users), and 6.4% of control subjects were hypertensive (SBP ≥140 and/or DBP ≥90 mm Hg) versus 1.9% of ethanol users (P = 0.051). Among preintervention kerosene users, 8.8% of control subjects were hypertensive compared with 1.8% of ethanol users (P = 0.029). To our knowledge, this is the first cookstove randomized controlled trial examining prenatal BP. Ethanol cookstoves have potential to reduce DBP and hypertension during pregnancy. Accordingly, clean cooking fuels may reduce adverse health impacts associated with household air pollution. Clinical trial registered with www.clinicaltrials.gov (NCT02394574).

A comparison of wearable fitness devices.

PubMed

Kaewkannate, Kanitthika; Kim, Soochan

2016-05-24

Wearable trackers can help motivate you during workouts and provide information about your daily routine or fitness in combination with your smartphone without requiring potentially disruptive manual calculations or records. This paper summarizes and compares wearable fitness devices, also called "fitness trackers" or "activity trackers." These devices are becoming increasingly popular in personal healthcare, motivating people to exercise more throughout the day without the need for lifestyle changes. The various choices in the market for wearable devices are also increasing, with customers searching for products that best suit their personal needs. Further, using a wearable device or fitness tracker can help people reach a fitness goal or finish line. Generally, companies display advertising for these kinds of products and depict them as beneficial, user friendly, and accurate. However, there are no objective research results to prove the veracity of their words. This research features subjective and objective experimental results, which reveal that some devices perform better than others. The four most popular wristband style wearable devices currently on the market (Withings Pulse, Misfit Shine, Jawbone Up24, and Fitbit Flex) are selected and compared. The accuracy of fitness tracking is one of the key components for fitness tracking, and some devices perform better than others. This research shows subjective and objective experimental results that are used to compare the accuracy of four wearable devices in conjunction with user friendliness and satisfaction of 7 real users. In addition, this research matches the opinions between reviewers on an Internet site and those of subjects when using the device. Withings Pulse is the most friendly and satisfactory from the users' viewpoint. It is the most accurate and repeatable for step and distance tracking, which is the most important measurement of fitness tracking, followed by Fitbit Flex, Jawbone Up24, and Misfit Shine. In contrast, Misfit Shine has the highest score for design and hardware, which is also appreciated by users. From the results of experiments on four wearable devices, it is determined that the most acceptable in terms of price and satisfaction levels is the Withings Pulse, followed by the Fitbit Flex, Jawbone Up24, and Misfit Shine.

Evidence for the innate immune response as a correlate of protection in human immunodeficiency virus (HIV)-1 highly exposed seronegative subjects (HESN)

PubMed Central

Tomescu, C; Abdulhaqq, S; Montaner, L J

2011-01-01

The description of highly exposed individuals who remain seronegative (HESN) despite repeated exposure to human immunodeficiency virus (HIV)-1 has heightened interest in identifying potential mechanisms of HIV-1 resistance. HIV-specific humoral and T cell-mediated responses have been identified routinely in HESN subjects, although it remains unknown if these responses are a definitive cause of protection or merely a marker for exposure. Approximately half of HESN lack any detectible HIV-specific adaptive immune responses, suggesting that other mechanisms of protection from HIV-1 infection also probably exist. In support of the innate immune response as a mechanism of resistance, increased natural killer (NK) cell activity has been correlated with protection from infection in several high-risk cohorts of HESN subjects, including intravenous drug users, HIV-1 discordant couples and perinatally exposed infants. Inheritance of protective NK KIR3DL1high and KIR3DS1 receptor alleles have also been observed to be over-represented in a high-risk cohort of HESN intravenous drug users and HESN partners of HIV-1-infected subjects. Other intrinsic mechanisms of innate immune protection correlated with resistance in HESN subjects include heightened dendritic cell responses and increased secretion of anti-viral factors such as β-chemokines, small anti-viral factors and defensins. This review will highlight the most current evidence in HESN subjects supporting the role of epithelial microenvironment and the innate immune system in sustaining resistance against HIV-1 infection. We will argue that as a front-line defence the innate immune response determines the threshold of infectivity that HIV-1 must overcome to establish a productive infection. PMID:21413945

[Physiological mechanisms of the etiology of visual fatigue during work involving visual stress].

PubMed

Korniushina, T A

2000-01-01

Physiological parameters of vision were studied in three professional groups (a total of 1204 subjects): microscope operators, subjects working with magnifying glasses, and computer users. General and specific features of visual system fatigue formation were identified. Because of complete (in microscope operators) or partial (in subjects working with magnifying glasses and display users) "deprivation" of accommodation, these subjects develop early presbyopia (at the age of 30-35 years). In microscope operators long strain of accommodation system leads to professional myopia, while display users develop pseudomyopia. The highest overstrain is observed after 4 years of work in microscope operators, after 5 years in magnifying glass users, and after 6 years in computer users.

The GRIDView Visualization Package

NASA Astrophysics Data System (ADS)

Kent, B. R.

2011-07-01

Large three-dimensional data cubes, catalogs, and spectral line archives are increasingly important elements of the data discovery process in astronomy. Visualization of large data volumes is of vital importance for the success of large spectral line surveys. Examples of data reduction utilizing the GRIDView software package are shown. The package allows users to manipulate data cubes, extract spectral profiles, and measure line properties. The package and included graphical user interfaces (GUIs) are designed with pipeline infrastructure in mind. The software has been used with great success analyzing spectral line and continuum data sets obtained from large radio survey collaborations. The tools are also important for multi-wavelength cross-correlation studies and incorporate Virtual Observatory client applications for overlaying database information in real time as cubes are examined by users.

Exploration of Web Users' Search Interests through Automatic Subject Categorization of Query Terms.

ERIC Educational Resources Information Center

Pu, Hsiao-tieh; Yang, Chyan; Chuang, Shui-Lung

2001-01-01

Proposes a mechanism that carefully integrates human and machine efforts to explore Web users' search interests. The approach consists of a four-step process: extraction of core terms; construction of subject taxonomy; automatic subject categorization of query terms; and observation of users' search interests. Research findings are proved valuable…

Wireless device connection problems and design solutions

NASA Astrophysics Data System (ADS)

Song, Ji-Won; Norman, Donald; Nam, Tek-Jin; Qin, Shengfeng

2016-09-01

Users, especially the non-expert users, commonly experience problems when connecting multiple devices with interoperability. While studies on multiple device connections are mostly concentrated on spontaneous device association techniques with a focus on security aspects, the research on user interaction for device connection is still limited. More research into understanding people is needed for designers to devise usable techniques. This research applies the Research-through-Design method and studies the non-expert users' interactions in establishing wireless connections between devices. The "Learning from Examples" concept is adopted to develop a study focus line by learning from the expert users' interaction with devices. This focus line is then used for guiding researchers to explore the non-expert users' difficulties at each stage of the focus line. Finally, the Research-through-Design approach is used to understand the users' difficulties, gain insights to design problems and suggest usable solutions. When connecting a device, the user is required to manage not only the device's functionality but also the interaction between devices. Based on learning from failures, an important insight is found that the existing design approach to improve single-device interaction issues, such as improvements to graphical user interfaces or computer guidance, cannot help users to handle problems between multiple devices. This study finally proposes a desirable user-device interaction in which images of two devices function together with a system image to provide the user with feedback on the status of the connection, which allows them to infer any required actions.

Spectral Transfer Learning Using Information Geometry for a User-Independent Brain-Computer Interface

PubMed Central

Waytowich, Nicholas R.; Lawhern, Vernon J.; Bohannon, Addison W.; Ball, Kenneth R.; Lance, Brent J.

2016-01-01

Recent advances in signal processing and machine learning techniques have enabled the application of Brain-Computer Interface (BCI) technologies to fields such as medicine, industry, and recreation; however, BCIs still suffer from the requirement of frequent calibration sessions due to the intra- and inter-individual variability of brain-signals, which makes calibration suppression through transfer learning an area of increasing interest for the development of practical BCI systems. In this paper, we present an unsupervised transfer method (spectral transfer using information geometry, STIG), which ranks and combines unlabeled predictions from an ensemble of information geometry classifiers built on data from individual training subjects. The STIG method is validated in both off-line and real-time feedback analysis during a rapid serial visual presentation task (RSVP). For detection of single-trial, event-related potentials (ERPs), the proposed method can significantly outperform existing calibration-free techniques as well as outperform traditional within-subject calibration techniques when limited data is available. This method demonstrates that unsupervised transfer learning for single-trial detection in ERP-based BCIs can be achieved without the requirement of costly training data, representing a step-forward in the overall goal of achieving a practical user-independent BCI system. PMID:27713685

Spectral Transfer Learning Using Information Geometry for a User-Independent Brain-Computer Interface.

PubMed

Waytowich, Nicholas R; Lawhern, Vernon J; Bohannon, Addison W; Ball, Kenneth R; Lance, Brent J

2016-01-01

Recent advances in signal processing and machine learning techniques have enabled the application of Brain-Computer Interface (BCI) technologies to fields such as medicine, industry, and recreation; however, BCIs still suffer from the requirement of frequent calibration sessions due to the intra- and inter-individual variability of brain-signals, which makes calibration suppression through transfer learning an area of increasing interest for the development of practical BCI systems. In this paper, we present an unsupervised transfer method (spectral transfer using information geometry, STIG), which ranks and combines unlabeled predictions from an ensemble of information geometry classifiers built on data from individual training subjects. The STIG method is validated in both off-line and real-time feedback analysis during a rapid serial visual presentation task (RSVP). For detection of single-trial, event-related potentials (ERPs), the proposed method can significantly outperform existing calibration-free techniques as well as outperform traditional within-subject calibration techniques when limited data is available. This method demonstrates that unsupervised transfer learning for single-trial detection in ERP-based BCIs can be achieved without the requirement of costly training data, representing a step-forward in the overall goal of achieving a practical user-independent BCI system.

TIGER: A graphically interactive grid system for turbomachinery applications

NASA Technical Reports Server (NTRS)

Shih, Ming-Hsin; Soni, Bharat K.

1992-01-01

Numerical grid generation algorithm associated with the flow field about turbomachinery geometries is presented. Graphical user interface is developed with FORMS Library to create an interactive, user-friendly working environment. This customized algorithm reduces the man-hours required to generate a grid associated with turbomachinery geometry, as compared to the use of general-purpose grid generation softwares. Bezier curves are utilized both interactively and automatically to accomplish grid line smoothness and orthogonality. Graphical User Interactions are provided in the algorithm, allowing the user to design and manipulate the grid lines with a mouse.

Leveraging Social Links for Trust and Privacy in Networks

NASA Astrophysics Data System (ADS)

Cutillo, Leucio Antonio; Molva, Refik; Strufe, Thorsten

Existing on-line social networks (OSN) such as Facebook suffer from several weaknesses regarding privacy and security due to their inherent handling of personal data. As pointed out in [4], a preliminary analysis of existing OSNs shows that they are subject to a number of vulnerabilities, ranging from cloning legitimate users to sybil attacks through privacy violations. Starting from these OSN vulnerabilities as the first step of a broader research activity, we came up with a new approach that is very promising in re-visiting security and privacy problems in distributed systems and networks. We suggest a solution that both aims at avoiding any centralized control and leverages on the real life trust between users, that is part of the social network application itself. An anonymization technique based on multi-hop routing among trusted nodes guarantees privacy in data access and, generally speaking, in all the OSN operations.

User Assessment of "InsuOnLine," a Game to Fight Clinical Inertia in Diabetes: A Pilot Study.

PubMed

Diehl, Leandro Arthur; de Souza, Rodrigo Martins; Gordan, Pedro Alejandro; Esteves, Roberto Zonato; Coelho, Izabel Cristina Meister

2015-10-01

We performed a pilot study to assess usability and playability of "InsuOnLine," a serious game for education of primary care physicians on insulin therapy for diabetes mellitus. A multidisciplinary team has designed and developed "InsuOnLine," using Andragogy and Problem-Based Learning principles, with game elements to improve players' motivation. The prototype was tested by four medical doctors and two medical students, using the System Usability Scale (SUS) and a questionnaire to assess playability. These results were used to guide corrections, after which the beta version was retested by 14 medical students and 6 residents. Out of a maximum score of 100 on the SUS, the "InsuOnLine" prototype was rated 88, and some areas for improvement were identified (game instructions, controls). After corrections, the beta version was rated 92.5 on the SUS. Users have found the beta version to be fun, engaging, challenging, relevant, and realistic. Users said that the game has increased their knowledge on diabetes and insulin, that it has made them feel more confident for prescribing insulin, and that it would have impact on how they treated patients with diabetes. Most users said they have learned more from the game than they would have from a lecture. Lessons learned were the need of early piloting, preferably by users with very little or very much gaming experience, on their own computers and free patterns of use. "InsuOnLine" was rated by users as easy to play, fun, and useful for learning. Further studies will assess its educational effectiveness. "InsuOnLine" is a promising tool for large-scale continuing medical education on insulin, helping to fight clinical inertia in diabetes.

A navigation system for the visually impaired using colored navigation lines and RFID tags.

PubMed

Seto, First Tatsuya

2009-01-01

In this paper, we describe about a developed navigation system that supports the independent walking of the visually impaired in the indoor space. Our developed instrument consists of a navigation system and a map information system. These systems are installed on a white cane. Our navigation system can follow a colored navigation line that is set on the floor. In this system, a color sensor installed on the tip of a white cane senses the colored navigation line, and the system informs the visually impaired that he/she is walking along the navigation line by vibration. The color recognition system is controlled by a one-chip microprocessor and this system can discriminate 6 colored navigation lines. RFID tags and a receiver for these tags are used in the map information system. The RFID tags and the RFID tag receiver are also installed on a white cane. The receiver receives tag information and notifies map information to the user by mp3 formatted pre-recorded voice. Three normal subjects who were blindfolded with an eye mask were tested with this system. All of them were able to walk along the navigation line. The performance of the map information system was good. Therefore, our system will be extremely valuable in supporting the activities of the visually impaired.

Reading Behind the Lines: The Factors Affecting the Text Reception Threshold in Hearing Aid Users.

PubMed

Zekveld, Adriana A; Pronk, Marieke; Danielsson, Henrik; Rönnberg, Jerker

2018-03-15

The visual Text Reception Threshold (TRT) test (Zekveld et al., 2007) has been designed to assess modality-general factors relevant for speech perception in noise. In the last decade, the test has been adopted in audiology labs worldwide. The 1st aim of this study was to examine which factors best predict interindividual differences in the TRT. Second, we aimed to assess the relationships between the TRT and the speech reception thresholds (SRTs) estimated in various conditions. First, we reviewed studies reporting relationships between the TRT and the auditory and/or cognitive factors and formulated specific hypotheses regarding the TRT predictors. These hypotheses were tested using a prediction model applied to a rich data set of 180 hearing aid users. In separate association models, we tested the relationships between the TRT and the various SRTs and subjective hearing difficulties, while taking into account potential confounding variables. The results of the prediction model indicate that the TRT is predicted by the ability to fill in missing words in incomplete sentences, by lexical access speed, and by working memory capacity. Furthermore, in line with previous studies, a moderate association between higher age, poorer pure-tone hearing acuity, and poorer TRTs was observed. Better TRTs were associated with better SRTs for the correct perception of 50% of Hagerman matrix sentences in a 4-talker babble, as well as with better subjective ratings of speech perception. Age and pure-tone hearing thresholds significantly confounded these associations. The associations of the TRT with SRTs estimated in other conditions and with subjective qualities of hearing were not statistically significant when adjusting for age and pure-tone average. We conclude that the abilities tapped into by the TRT test include processes relevant for speeded lexical decision making when completing partly masked sentences and that these processes require working memory capacity. Furthermore, the TRT is associated with the SRT of hearing aid users as estimated in a challenging condition that includes informational masking and with experienced difficulties with speech perception in daily-life conditions. The current results underline the value of using the TRT test in studies involving speech perception and aid in the interpretation of findings acquired using the test.

Transmission Line Jobs and Economic Development Impact (JEDI) Model User Reference Guide

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goldberg, M.; Keyser, D.

The Jobs and Economic Development Impact (JEDI) models, developed through the National Renewable Energy Laboratory (NREL), are freely available, user-friendly tools that estimate the potential economic impacts of constructing and operating power generation projects for a range of conventional and renewable energy technologies. The Transmission Line JEDI model can be used to field questions about the economic impacts of transmission lines in a given state, region, or local community. This Transmission Line JEDI User Reference Guide was developed to provide basic instruction on operating the model and understanding the results. This guide also provides information on the model's underlying methodology,more » as well as the parameters and references used to develop the cost data contained in the model.« less

Critical Review of NOAA's Observation Requirements Process

NASA Astrophysics Data System (ADS)

LaJoie, M.; Yapur, M.; Vo, T.; Templeton, A.; Bludis, D.

2017-12-01

NOAA's Observing Systems Council (NOSC) maintains a comprehensive database of user observation requirements. The requirements collection process engages NOAA subject matter experts to document and effectively communicate the specific environmental observation measurements (parameters and attributes) needed to produce operational products and pursue research objectives. User observation requirements documented using a structured and standardized manner and framework enables NOAA to assess its needs across organizational lines in an impartial, objective, and transparent manner. This structure provides the foundation for: selecting, designing, developing, acquiring observing technologies, systems and architectures; budget and contract formulation and decision-making; and assessing in a repeatable fashion the productivity, efficiency and optimization of NOAA's observing system enterprise. User observation requirements are captured independently from observing technologies. Therefore, they can be addressed by a variety of current or expected observing capabilities and allow flexibility to be remapped to new and evolving technologies. NOAA's current inventory of user observation requirements were collected over a ten-year period, and there have been many changes in policies, mission priorities, and funding levels during this time. In light of these changes, the NOSC initiated a critical, in-depth review to examine all aspects of user observation requirements and associated processes during 2017. This presentation provides background on the NOAA requirements process, major milestones and outcomes of the critical review, and plans for evolving and connecting observing requirements processes in the next year.

Legal, social, cultural and political developments in mental health care in the UK: the Liverpool black mental health service users' perspective.

PubMed

Pierre, S A

2002-02-01

Documentary evidence suggests that attitudes among local health and social services professionals towards the concept of user involvement in health and social care remain deeply polarized, a position characterized by commentators simultaneously as praise and damnation. Perhaps user involvement in health and social care will enhance, and it appears to resonate with the logic of, participatory democracy, in localities where the centralization of power has posed questions as to the nature and purpose of local governance in public services provision. The problems experienced by Britain's black and ethnic minorities within the mental health system have been the subject of exhaustive social inquiry. This essay attempts to explore the way in which legal, social, cultural, and political developments interface with mental health care practice in the UK, in order to assist those responsible for mental health services provision to deliver services that are in line with the Government's expectation of a modernized mental health service that is safe, sound, and supportive. An exploration of these developments within the European, national (UK), and local (Liverpool) contexts is undertaken. An appropriate local response to national priorities will ostensibly cut a swathe through the barriers confronted by the ethnic minority mental health service user in the cross-cultural context, an important prerequisite for the implementation of genuine user involvement.

The FTS atomic spectrum tool (FAST) for rapid analysis of line spectra

NASA Astrophysics Data System (ADS)

Ruffoni, M. P.

2013-07-01

The FTS Atomic Spectrum Tool (FAST) is an interactive graphical program designed to simplify the analysis of atomic emission line spectra obtained from Fourier transform spectrometers. Calculated, predicted and/or known experimental line parameters are loaded alongside experimentally observed spectral line profiles for easy comparison between new experimental data and existing results. Many such line profiles, which could span numerous spectra, may be viewed simultaneously to help the user detect problems from line blending or self-absorption. Once the user has determined that their experimental line profile fits are good, a key feature of FAST is the ability to calculate atomic branching fractions, transition probabilities, and oscillator strengths-and their uncertainties-which is not provided by existing analysis packages. Program SummaryProgram title: FAST: The FTS Atomic Spectrum Tool Catalogue identifier: AEOW_v1_0 Program summary URL: http://cpc.cs.qub.ac.uk/summaries/AEOW_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: GNU General Public License version 3 No. of lines in distributed program, including test data, etc.: 293058 No. of bytes in distributed program, including test data, etc.: 13809509 Distribution format: tar.gz Programming language: C++. Computer: Intel x86-based systems. Operating system: Linux/Unix/Windows. RAM: 8 MB minimum. About 50-200 MB for a typical analysis. Classification: 2.2, 2.3, 21.2. Nature of problem: Visualisation of atomic line spectra including the comparison of theoretical line parameters with experimental atomic line profiles. Accurate intensity calibration of experimental spectra, and the determination of observed relative line intensities that are needed for calculating atomic branching fractions and oscillator strengths. Solution method: FAST is centred around a graphical interface, where a user may view sets of experimental line profiles and compare them to calculated data (such as from the Kurucz database [1]), predicted line parameters, and/or previously known experimental results. With additional information on the spectral response of the spectrometer, obtained from a calibrated standard light source, FT spectra may be intensity calibrated. In turn, this permits the user to calculate atomic branching fractions and oscillator strengths, and their respective uncertainties. Running time: Open ended. Defined by the user. References: [1] R.L. Kurucz (2007). URL http://kurucz.harvard.edu/atoms/.

Cryogenic Propellant Feed System Analytical Tool Development

NASA Technical Reports Server (NTRS)

Lusby, Brian S.; Miranda, Bruno M.; Collins, Jacob A.

2011-01-01

The Propulsion Systems Branch at NASA s Lyndon B. Johnson Space Center (JSC) has developed a parametric analytical tool to address the need to rapidly predict heat leak into propellant distribution lines based on insulation type, installation technique, line supports, penetrations, and instrumentation. The Propellant Feed System Analytical Tool (PFSAT) will also determine the optimum orifice diameter for an optional thermodynamic vent system (TVS) to counteract heat leak into the feed line and ensure temperature constraints at the end of the feed line are met. PFSAT was developed primarily using Fortran 90 code because of its number crunching power and the capability to directly access real fluid property subroutines in the Reference Fluid Thermodynamic and Transport Properties (REFPROP) Database developed by NIST. A Microsoft Excel front end user interface was implemented to provide convenient portability of PFSAT among a wide variety of potential users and its ability to utilize a user-friendly graphical user interface (GUI) developed in Visual Basic for Applications (VBA). The focus of PFSAT is on-orbit reaction control systems and orbital maneuvering systems, but it may be used to predict heat leak into ground-based transfer lines as well. PFSAT is expected to be used for rapid initial design of cryogenic propellant distribution lines and thermodynamic vent systems. Once validated, PFSAT will support concept trades for a variety of cryogenic fluid transfer systems on spacecraft, including planetary landers, transfer vehicles, and propellant depots, as well as surface-based transfer systems. The details of the development of PFSAT, its user interface, and the program structure will be presented.

Investigation of the effect of cochlear implant electrode length on speech comprehension in quiet and noise compared with the results with users of electro-acoustic-stimulation, a retrospective analysis

PubMed Central

Majdani, Omid; Lenarz, Thomas

2017-01-01

Objectives This investigation evaluated the effect of cochlear implant (CI) electrode length on speech comprehension in quiet and noise and compare the results with those of EAS users. Methodes 91 adults with some degree of residual hearing were implanted with a FLEX20, FLEX24, or FLEX28 electrode. Some subjects were postoperative electric-acoustic-stimulation (EAS) users; the other subjects were in the groups of electric stimulation-only (ES-only). Speech perception was tested in quiet and noise at 3 and 6 months of ES or EAS use. Speech comprehension results were analyzed and correlated to electrode length. Results While the FLEX20 ES and FLEX24 ES groups were still in their learning phase between the 3 to 6 months interval, the FLEX28 ES group was already reaching a performance plateau at the three months appointment yielding remarkably high test scores. EAS subjects using FLEX20 or FLEX24 electrodes outscored ES-only subjects with the same short electrodes on all 3 tests at each interval, reaching significance with FLEX20 ES and FLEX24 ES subjects on all 3 tests at the 3-months interval and on 2 tests at the 6- months interval. Amongst ES-only subjects at the 3- months interval, FLEX28 ES subjects significantly outscored FLEX20 ES subjects on all 3 tests and the FLEX24 ES subjects on 2 tests. At the-6 months interval, FLEX28 ES subjects still exceeded the other ES-only subjects although the difference did not reach significance. Conclusions Among ES-only users, the FLEX28 ES users had the best speech comprehension scores, at the 3- months appointment and tendentially at the 6 months appointment. EAS users showed significantly better speech comprehension results compared to ES-only users with the same short electrodes. PMID:28505158

Investigation of the effect of cochlear implant electrode length on speech comprehension in quiet and noise compared with the results with users of electro-acoustic-stimulation, a retrospective analysis.

PubMed

Büchner, Andreas; Illg, Angelika; Majdani, Omid; Lenarz, Thomas

2017-01-01

This investigation evaluated the effect of cochlear implant (CI) electrode length on speech comprehension in quiet and noise and compare the results with those of EAS users. 91 adults with some degree of residual hearing were implanted with a FLEX20, FLEX24, or FLEX28 electrode. Some subjects were postoperative electric-acoustic-stimulation (EAS) users; the other subjects were in the groups of electric stimulation-only (ES-only). Speech perception was tested in quiet and noise at 3 and 6 months of ES or EAS use. Speech comprehension results were analyzed and correlated to electrode length. While the FLEX20 ES and FLEX24 ES groups were still in their learning phase between the 3 to 6 months interval, the FLEX28 ES group was already reaching a performance plateau at the three months appointment yielding remarkably high test scores. EAS subjects using FLEX20 or FLEX24 electrodes outscored ES-only subjects with the same short electrodes on all 3 tests at each interval, reaching significance with FLEX20 ES and FLEX24 ES subjects on all 3 tests at the 3-months interval and on 2 tests at the 6- months interval. Amongst ES-only subjects at the 3- months interval, FLEX28 ES subjects significantly outscored FLEX20 ES subjects on all 3 tests and the FLEX24 ES subjects on 2 tests. At the-6 months interval, FLEX28 ES subjects still exceeded the other ES-only subjects although the difference did not reach significance. Among ES-only users, the FLEX28 ES users had the best speech comprehension scores, at the 3- months appointment and tendentially at the 6 months appointment. EAS users showed significantly better speech comprehension results compared to ES-only users with the same short electrodes.

fgui: A Method for Automatically Creating Graphical User Interfaces for Command-Line R Packages

PubMed Central

Hoffmann, Thomas J.; Laird, Nan M.

2009-01-01

The fgui R package is designed for developers of R packages, to help rapidly, and sometimes fully automatically, create a graphical user interface for a command line R package. The interface is built upon the Tcl/Tk graphical interface included in R. The package further facilitates the developer by loading in the help files from the command line functions to provide context sensitive help to the user with no additional effort from the developer. Passing a function as the argument to the routines in the fgui package creates a graphical interface for the function, and further options are available to tweak this interface for those who want more flexibility. PMID:21625291

Easy-To-Use Connector-Assembly Tool

NASA Technical Reports Server (NTRS)

Redmon, John W., Jr.; Jankowski, Fred

1988-01-01

Tool compensates for user's loss of dexterity under awkward conditions. Has jaws that swivel over 180 degree so angle adjusts with respect to handles. Oriented and held in position most comfortable and effective for user in given situation. Jaws lined with rubber pads so they conform to irregularly shaped parts and grips firmly but gently. Once tool engages part, it locks on it so user can release handles without losing part. Ratchet mechanism in tool allows user to work handles back and forth in confined space to connect or disconnect part. Quickly positioned, locked, and released. Gives user feel of its grip on part. Frees grasping muscles from work during part of task, giving user greater freedom to move hand. Operates with only one hand, leaving user's other hand free to manipulate wiring or other parts. Also adapts to handling and positioning extremely-hot or extremely-cold fluid lines, contaminated objects, abrasive or sharp objects, fragile items, and soft objects.

A preliminary evaluation of synthetic cannabinoid use among adolescent cannabis users: Characteristics and treatment outcomes.

PubMed

Blevins, Claire E; Banes, Kelsey E; Stephens, Robert S; Walker, Denise D; Roffman, Roger A

2016-12-01

Little is known regarding the use of synthetic cannabinoids (SC), particularly use among adolescent substance users who may be at higher risk. The present exploratory study seeks to describe SC use and subjective effects among cannabis-using adolescents as well as compare the characteristics of cannabis users who do and do not use SC. Exploratory analyses evaluated cannabis treatment outcomes among SC users and non-users. Participants enrolled in a randomized, controlled intervention for cannabis-using high school students aged 14-19 (N=252) completed questionnaires regarding their use of SC and other substances. Those who used SC in the past 60days reported subjective effects of SC, consequences, and SC use disorder symptoms. Baseline characteristics, alcohol and other drug use, and treatment outcomes of SC users were compared to participants who never tried SC. Within this sample 29% had tried SC, and 6% used SC recently. Although most reported use at a relatively low rate, 43% of recent SC users reported SC use-disorder symptoms. Positive and negative subjective effects of SC were endorsed, with positive subjective effects reported more often. SC use was associated with more cannabis use, but not more alcohol or other (non-SC and non-cannabis) drug use. SC users did not differ from non-users on cannabis treatment outcomes. This exploratory study described SC use, and compared characteristics and treatment outcomes among SC users and non-users. Negative subjective effects of SC were reported as occurring less often, but SC use was associated with use disorder psychopathology. SC use was associated with more problematic cannabis use at baseline, but was not associated with use of other substances or differences in treatment outcome. Copyright © 2016 Elsevier Ltd. All rights reserved.

47 CFR 69.609 - End User Common Line hypothetical net balances.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 3 2011-10-01 2011-10-01 false End User Common Line hypothetical net balances... net balances. (a) If the company does not participate in the association tariff for such element, the hypothetical net balance shall be zero. (b) If the company does participate in the association tariff for such...

47 CFR 69.609 - End User Common Line hypothetical net balances.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 3 2010-10-01 2010-10-01 false End User Common Line hypothetical net balances... net balances. (a) If the company does not participate in the association tariff for such element, the hypothetical net balance shall be zero. (b) If the company does participate in the association tariff for such...

LIME: Semiautomated line measurement and identification from stellar spectra

NASA Astrophysics Data System (ADS)

Sahin, T.

2017-09-01

We present LIME (Line Measurements from ECHELLE Spectra), an IDL-based code, as a powerful tool for semiautomated stellar line measurement and identification. Interactively selected line positions (i.e. wavelengths) are compared with a master line list of the user's selections. Each unknown line that the user interactively chooses is displayed with potential identifications provided by the code in the vicinity of the selected line. The best identification is evaluated on the basis of several criteria (e.g., atomic/molecular line information, wavelength displacement, and theoretical equivalent width for solar atmospheric values). We examined the identifications by LIME in the spectra of post-red supergiant star HD 179821 over a range of signal-to-noise values and wavelength ranges. We found that the results obtained by LIME show virtually complete agreement with the manual identifications for which the conventional and also tedious approach is to use a revised multiplet table as an initial guide and perform a systematic search that makes use of the lower excitation potential and gf-values. Comparison to previous identifications for HD 179821 in the literature revealed not only lines that were unmeasurable and/or blended but also misidentifications. While a manual identification process takes a relatively longer time to be accomplished by an experienced spectroscopist, LIME can provide a rapid extraction of line information in a few hours with moderate user interaction.

Well-being, problematic alcohol consumption and acute subjective drug effects in past-year ayahuasca users: a large, international, self-selecting online survey.

PubMed

Lawn, Will; Hallak, Jaime E; Crippa, Jose A; Dos Santos, Rafael; Porffy, Lilla; Barratt, Monica J; Ferris, Jason A; Winstock, Adam R; Morgan, Celia J A

2017-11-09

Ayahuasca is a natural psychedelic brew, which contains dimethyltryptamine (DMT). Its potential as a psychiatric medicine has recently been demonstrated and its non-medical use around the world appears to be growing. We aimed to investigate well-being and problematic alcohol use in ayahuasca users, and ayahuasca's subjective effects. An online, self-selecting, global survey examining patterns of drug use was conducted in 2015 and 2016 (n = 96,901). Questions were asked about: use of ayahuasca, lysergic acid diethylamide (LSD) and magic mushrooms; demographics, current well-being and past-year problematic alcohol use of past-year ayahuasca users and comparison drug users; and subjective effects of ayahuasca and comparison drugs. Ayahuasca users (n = 527) reported greater well-being than both classic psychedelic users (n = 18,138) and non-psychedelic drug-using respondents (n = 78,236). Ayahuasca users reported less problematic drinking than classic psychedelic users, although both groups reported greater problematic drinking than the other respondents. Ayahuasca's acute subjective effects usually lasted for six hours and were most strongly felt one hour after consumption. Within our online, self-selecting survey, ayahuasca users reported better well-being than comparison groups and less problematic drinking than classic psychedelic users. Future longitudinal studies of international samples and randomised controlled trials are needed to dissect the effects of ayahuasca on these outcomes.

Decreased cerebral blood flow of the right anterior cingulate cortex in long-term and short-term abstinent methamphetamine users.

PubMed

Hwang, Jaeuk; Lyoo, In Kyoon; Kim, Seog Ju; Sung, Young Hoon; Bae, Soojeong; Cho, Sung-Nam; Lee, Ho Young; Lee, Dong Soo; Renshaw, Perry F

2006-04-28

The aim of the current study was to explore changes of relative regional cerebral blood flow (rCBF) in short-term and long-term abstinent methamphetamine (MA) users. Relative rCBF in 40 abstinent MA users and 23 healthy comparison subjects was compared by the technetium-99m-hexamethyl-propylene amine oxime ((99m)Tc-HMPAO) single photon emission computed tomography (SPECT). Relative rCBF in areas that were found to differ significantly was also compared in groups of MA users with short-term (<6 months) and long-term (>or=6 months) abstinence. MA users showed decreased relative rCBF in the right anterior cingulate cortex (Brodmann area 32) relative to healthy comparison subjects. Long-term abstinent MA users had significantly greater rCBF than short-term abstinent MA users. We report that abstinent MA users have decreased rCBF in the anterior cingulate cortex with smaller relative decreases in subjects with prolonged abstinence.

Multicentre evaluation of music perception in adult users of Advanced Bionics cochlear implants.

PubMed

Adams, Doris; Ajimsha, Khalid Mohamed; Barberá, Manuel Tomás; Gazibegovic, Dzemal; Gisbert, Javier; Gómez, Justo; Raveh, Eyal; Rocca, Christine; Romanet, Philipe; Seebens, Yvonne; Zarowski, Andrzej

2014-01-01

To document musical listening and enjoyment in recipients of Advanced Bionics cochlear implants (CIs) and to compare musical perception in those using early coding strategies with subjects using the newer HiRes and HiRes 120 strategies. A questionnaire was completed by 136 adult subjects, including questions on the ability to identify specific musical features. The subjects were in three groups: those using early coding strategies (n = 29), HiRes (n = 59), and HiRes 120 (n = 48), and results were compared with a group of 84 normally hearing (NH) subjects. Of the CI users, 79% reported listening to music. The NH group rated listening frequency and enjoyment higher than the CI users. Thirty-five users reported that they sang and this group had significantly higher overall performance. There were no significant differences in overall perception of specific musical features among the strategy groups, though some individual questions showed significantly higher performance in the HiRes 120 users. Users of current CI technology show a high level of musical appreciation, though still significantly less than NH subjects. Frequency of listening and enjoyment were significantly correlated and active participation in musical activities, specifically singing, resulted in significantly higher overall performance scores.

The influence of prototype fidelity and aesthetics of design in usability tests: effects on user behaviour, subjective evaluation and emotion.

PubMed

Sauer, Juergen; Sonderegger, Andreas

2009-07-01

An empirical study examined the impact of prototype fidelity on user behaviour, subjective user evaluation and emotion. The independent factors of prototype fidelity (paper prototype, computer prototype, fully operational appliance) and aesthetics of design (high vs. moderate) were varied in a between-subjects design. The 60 participants of the experiment were asked to complete two typical tasks of mobile phone usage: sending a text message and suppressing a phone number. Both performance data and a number of subjective measures were recorded. The results suggested that task completion time may be overestimated when a computer prototype is being used. Furthermore, users appeared to compensate for deficiencies in aesthetic design by overrating the aesthetic qualities of reduced fidelity prototypes. Finally, user emotions were more positively affected by the operation of the more attractive mobile phone than by the less appealing one.

Detection and display of acoustic window for guiding and training cardiac ultrasound users

NASA Astrophysics Data System (ADS)

Huang, Sheng-Wen; Radulescu, Emil; Wang, Shougang; Thiele, Karl; Prater, David; Maxwell, Douglas; Rafter, Patrick; Dupuy, Clement; Drysdale, Jeremy; Erkamp, Ramon

2014-03-01

Successful ultrasound data collection strongly relies on the skills of the operator. Among different scans, echocardiography is especially challenging as the heart is surrounded by ribs and lung tissue. Less experienced users might acquire compromised images because of suboptimal hand-eye coordination and less awareness of artifacts. Clearly, there is a need for a tool that can guide and train less experienced users to position the probe optimally. We propose to help users with hand-eye coordination by displaying lines overlaid on B-mode images. The lines indicate the edges of blockages (e.g., ribs) and are updated in real time according to movement of the probe relative to the blockages. They provide information about how probe positioning can be improved. To distinguish between blockage and acoustic window, we use coherence, an indicator of channel data similarity after applying focusing delays. Specialized beamforming was developed to estimate coherence. Image processing is applied to coherence maps to detect unblocked beams and the angle of the lines for display. We built a demonstrator based on a Philips iE33 scanner, from which beamsummed RF data and video output are transferred to a workstation for processing. The detected lines are overlaid on B-mode images and fed back to the scanner display to provide users real-time guidance. Using such information in addition to B-mode images, users will be able to quickly find a suitable acoustic window for optimal image quality, and improve their skill.

Numerical analysis of stiffened shells of revolution. Volume 2: Users' manual for STAR-02S - shell theory automated for rotational structures - 2 (statics), digital computer program

NASA Technical Reports Server (NTRS)

Svalbonas, V.

1973-01-01

A procedure for the structural analysis of stiffened shells of revolution is presented. A digital computer program based on the Love-Reissner first order shell theory was developed. The computer program can analyze orthotropic thin shells of revolution, subjected to unsymmetric distributed loading or concentrated line loads, as well as thermal strains. The geometrical shapes of the shells which may be analyzed are described. The shell wall cross section can be a sheet, sandwich, or reinforced sheet or sandwich. General stiffness input options are also available.

Cocaine effects on pulsatile secretion of anterior pituitary, gonadal, and adrenal hormones.

PubMed

Mendelson, J H; Mello, N K; Teoh, S K; Ellingboe, J; Cochin, J

1989-12-01

Pulse frequency analysis of LH, PRL, testosterone, and cortisol was carried out with the Cluster Analysis Program in eight male cocaine abusers and eight aged-matched normal men. Four of the eight cocaine abusers had hyperprolactinemia (range, 22.08-44.65 micrograms/L). Cocaine users as a group had significantly higher mean peak height (P less than 0.02) than control subjects. Cocaine users with hyperprolactinemia had higher mean peak height than control subjects or cocaine users with normal PRL levels (P less than 0.01). Cocaine users with hyperprolactinemia also had higher mean amplitude increments than control subjects (P less than 0.02). Cocaine users with hyperprolactinemia had a higher mean valley than controls (P less than 0.01) and cocaine users with normal PRL levels (P less than 0.03). However, there were no significant differences in PRL peak frequency, peak duration, or interpulse intervals between cocaine users with or without hyperprolactinemia and control subjects. There were minimal differences between cocaine users and control subjects in pulse frequency analysis of LH parameters; the small differences in mean LH levels and average interpulse interval were not in the abnormal range and were probably not biologically significant. No differences between cocaine users and controls were detected for pulse frequency analysis of testosterone or cortisol. Cocaine-induced hyperprolactinemia may contribute to disorders of sexual and reproductive function in men who abuse the drug, and recent reports that PRL modulates immune function suggest that cocaine-induced derangements of PRL secretion may also contribute to cocaine-related comorbidity in infectious disease. Since cocaine users with hyperprolactinemia had a higher mean valley as well as a higher peak pulse PRL height than control subjects, but did not have greater PRL pulse frequencies, we conclude that hyperprolactinemia in these men may be due to a cocaine-induced derangement of dopaminergic inhibition of basal PRL secretion.

Incentive-Rewarding Mechanism for User-position Control in Mobile Services

NASA Astrophysics Data System (ADS)

Yoshino, Makoto; Sato, Kenichiro; Shinkuma, Ryoichi; Takahashi, Tatsuro

When the number of users in a service area increases in mobile multimedia services, no individual user can obtain satisfactory radio resources such as bandwidth and signal power because the resources are limited and shared. A solution for such a problem is user-position control. In the user-position control, the operator informs users of better communication areas (or spots) and navigates them to these positions. However, because of subjective costs caused by subjects moving from their original to a new position, they do not always attempt to move. To motivate users to contribute their resources in network services that require resource contributions for users, incentive-rewarding mechanisms have been proposed. However, there are no mechanisms that distribute rewards appropriately according to various subjective factors involving users. Furthermore, since the conventional mechanisms limit how rewards are paid, they are applicable only for the network service they targeted. In this paper, we propose a novel incentive-rewarding mechanism to solve these problems, using an external evaluator and interactive learning agents. We also investigated ways of appropriately controlling rewards based on user contributions and system service quality. We applied the proposed mechanism and reward control to the user-position control, and demonstrated its validity.

Spectral Transfer Learning Using Information Geometry for a User-Independent Brain-Computer Interface

DOE PAGES

Waytowich, Nicholas R.; Lawhern, Vernon J.; Bohannon, Addison W.; ...

2016-09-22

Recent advances in signal processing and machine learning techniques have enabled the application of Brain-Computer Interface (BCI) technologies to fields such as medicine, industry, and recreation; however, BCIs still suffer from the requirement of frequent calibration sessions due to the intra- and inter-individual variability of brain-signals, which makes calibration suppression through transfer learning an area of increasing interest for the development of practical BCI systems. In this paper, we present an unsupervised transfer method (spectral transfer using information geometry,STIG),which ranks and combines unlabeled predictions from an ensemble of information geometry classifiers built on data from individual training subjects. The STIGmore » method is validated in both off-line and real-time feedback analysis during a rapid serial visual presentation task (RSVP). For detection of single-trial, event-related potentials (ERPs), the proposed method can significantly outperform existing calibration-free techniques as well as out perform traditional within-subject calibration techniques when limited data is available. Here, this method demonstrates that unsupervised transfer learning for single-trial detection in ERP-based BCIs can be achieved without the requirement of costly training data, representing a step-forward in the overall goal of achieving a practical user-independent BCI system.« less

Cybercrime Victimization and Subjective Well-Being: An Examination of the Buffering Effect Hypothesis Among Adolescents and Young Adults.

PubMed

Kaakinen, Markus; Keipi, Teo; Räsänen, Pekka; Oksanen, Atte

2018-02-01

The wealth of beneficial tools for online interaction, consumption, and access to others also bring new risks for harmful experiences online. This study examines the association between cybercrime victimization and subjective well-being (SWB) and, based on the buffering effect hypothesis, tests the assumption of the protective function of social belonging in cybercrime victimization. Cross-national data from the United States, United Kingdom, Germany, and Finland (N = 3,557; Internet users aged 15-30 years; 49.85 percent female) were analyzed using descriptive statistics and main and moderation effect models. Results show that cybercrime victimization has a negative association with SWB after adjusting for a number of confounding factors. This association concerns both general cybercrime victimization and subcategories such as victimization to offensive cybercrime and cyberfraud. In line with the buffering effect hypothesis, social belonging to offline groups was shown to moderate the negative association between SWB and cybercrime victimization. The same effect was not found in the social belonging to online groups. Overall, the study indicates that, analogously to crime victimization in the offline context, cybercrime is a harmful experience whose negative effects mainly concern those users who have weak social ties offline to aid in coping with such stressors.

Spectral Transfer Learning Using Information Geometry for a User-Independent Brain-Computer Interface

DOE Office of Scientific and Technical Information (OSTI.GOV)

Waytowich, Nicholas R.; Lawhern, Vernon J.; Bohannon, Addison W.

Recent advances in signal processing and machine learning techniques have enabled the application of Brain-Computer Interface (BCI) technologies to fields such as medicine, industry, and recreation; however, BCIs still suffer from the requirement of frequent calibration sessions due to the intra- and inter-individual variability of brain-signals, which makes calibration suppression through transfer learning an area of increasing interest for the development of practical BCI systems. In this paper, we present an unsupervised transfer method (spectral transfer using information geometry,STIG),which ranks and combines unlabeled predictions from an ensemble of information geometry classifiers built on data from individual training subjects. The STIGmore » method is validated in both off-line and real-time feedback analysis during a rapid serial visual presentation task (RSVP). For detection of single-trial, event-related potentials (ERPs), the proposed method can significantly outperform existing calibration-free techniques as well as out perform traditional within-subject calibration techniques when limited data is available. Here, this method demonstrates that unsupervised transfer learning for single-trial detection in ERP-based BCIs can be achieved without the requirement of costly training data, representing a step-forward in the overall goal of achieving a practical user-independent BCI system.« less

Thus Spake the OPAC User.

ERIC Educational Resources Information Center

Markey, Karen

1983-01-01

Findings of focused-group interviews conducted for OCLC study of library users and online public access catalogs (OPACs) indicate users like OPACs, have problems finding right subject heading, envision features to improve subject access, want access to more than books, and want OPACs to provide new services. Eight references are listed. (EJS)

40 CFR 403.12 - Reporting requirements for POTW's and industrial users.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Industrial Users subject to equivalent mass or concentration limits established by the Control Authority in... for the duration of the effective period of the Permit or other equivalent individual control... Industrial Users subject to equivalent mass or concentration limits established by the Control Authority in...

OPACs: The User and Subject Access.

ERIC Educational Resources Information Center

Carson, Elizabeth

1985-01-01

This survey of the literature reveals user and professional opinions of changes in subject access features available for online public access catalogs. Highlights include expanded access to fields already incorporated into traditional MARC record, access to context of the record, and design of the user interface. Twenty-four references are cited.…

Power User Interface

NASA Technical Reports Server (NTRS)

Pfister, Robin; McMahon, Joe

2006-01-01

Power User Interface 5.0 (PUI) is a system of middleware, written for expert users in the Earth-science community, PUI enables expedited ordering of data granules on the basis of specific granule-identifying information that the users already know or can assemble. PUI also enables expert users to perform quick searches for orderablegranule information for use in preparing orders. PUI 5.0 is available in two versions (note: PUI 6.0 has command-line mode only): a Web-based application program and a UNIX command-line- mode client program. Both versions include modules that perform data-granule-ordering functions in conjunction with external systems. The Web-based version works with Earth Observing System Clearing House (ECHO) metadata catalog and order-entry services and with an open-source order-service broker server component, called the Mercury Shopping Cart, that is provided separately by Oak Ridge National Laboratory through the Department of Energy. The command-line version works with the ECHO metadata and order-entry process service. Both versions of PUI ultimately use ECHO to process an order to be sent to a data provider. Ordered data are provided through means outside the PUI software system.

SAFARI, an On-Line Text-Processing System User's Manual.

ERIC Educational Resources Information Center

Chapin, P.G.; And Others.

This report describes for the potential user a set of procedures for processing textual materials on-line. In this preliminary model an information analyst can scan through messages, reports, and other documents on a display scope and select relevant facts, which are processed linguistically and then stored in the computer in the form of logical…

The varieties of ecstatic experience: an exploration of the subjective experiences of ecstasy.

PubMed

Sumnall, Harry R; Cole, Jon C; Jerome, Lisa

2006-09-01

Previous investigations of the subjective effects of MDMA (material sold as ecstasy) have conducted interviews and surveys of various groups of ecstasy users within particular sub-populations. This study examined subjective drug effects reported by different sub-populations of ecstasy users and explored whether the function or purpose served by using ecstasy influenced the nature of the drug experience. Drawing on previous measures of alterations in consciousness, psychedelic drugs and cannabis, and informal interviews with ecstasy users and MDMA researchers, a 130-item survey assessing subjective effects of ecstasy/MDMA was developed. Principal components analysis of responses of ecstasy users revealed six components; perceptual alterations, entactogenic effects, prosocial effects, aesthetic effects, negative effects and sexual effects. The derived scale was used to predict ecstasy use behaviours, and functions and experiences of use. A variety of component scores were related to ecstasy use parameters; in particular, heavier users expected fewer negative, perceptual and aesthetic effects from taking the drug. The reasons given for using ecstasy (use function) also influenced reported drug effects. Abstainers expected greater negative, perceptual, aesthetic and sexual effects than users. These data indicate that the subjective ecstasy experience is influenced by a variety of extra-psychopharmacological factors. Drug intervention strategies may be made more effective by targeting particular user groups defined by reasons given for substance use, as it is likely that their experiences of ecstasy effects will differ. Future research into ecstasy may be improved by recognizing user diversity.

Subjective aggression during alcohol and cannabis intoxication before and after aggression exposure.

PubMed

De Sousa Fernandes Perna, E B; Theunissen, E L; Kuypers, K P C; Toennes, S W; Ramaekers, J G

2016-09-01

Alcohol and cannabis use have been implicated in aggression. Alcohol consumption is known to facilitate aggression, whereas a causal link between cannabis and aggression has not been clearly demonstrated. This study investigated the acute effects of alcohol and cannabis on subjective aggression in alcohol and cannabis users, respectively, following aggression exposure. Drug-free controls served as a reference. It was hypothesized that aggression exposure would increase subjective aggression in alcohol users during alcohol intoxication, whereas it was expected to decrease subjective aggression in cannabis users during cannabis intoxication. Heavy alcohol (n = 20) and regular cannabis users (n = 21), and controls (n = 20) were included in a mixed factorial study. Alcohol and cannabis users received single doses of alcohol and placebo or cannabis and placebo, respectively. Subjective aggression was assessed before and after aggression exposure consisting of administrations of the point-subtraction aggression paradigm (PSAP) and the single category implicit association test (SC-IAT). Testosterone and cortisol levels in response to alcohol/cannabis treatment and aggression exposure were recorded as secondary outcome measures. Subjective aggression significantly increased following aggression exposure in all groups while being sober. Alcohol intoxication increased subjective aggression whereas cannabis decreased the subjective aggression following aggression exposure. Aggressive responses during the PSAP increased following alcohol and decreased following cannabis relative to placebo. Changes in aggressive feeling or response were not correlated to the neuroendocrine response to treatments. It is concluded that alcohol facilitates feelings of aggression whereas cannabis diminishes aggressive feelings in heavy alcohol and regular cannabis users, respectively.

Mining Social Tagging Data for Enhanced Subject Access for Readers and Researchers

ERIC Educational Resources Information Center

Lawson, Karen G.

2009-01-01

Social tagging enables librarians to partner with users to provide enhanced subject access. This paper quantifies and compares LC subject headings from each of 31 different subject divisions with user tags from Amazon.com and LibraryThing assigned to the same titles. The intersection and integration of these schemas is described and evaluated.…

FEDIX: The on-line database retrieval service of government information for colleges, universities, and other organizations. User`s guide, Version 4.0/Release 2.1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

FEDIX is an on-line information service that links the higher education community and the federal government to facilitate research, education, and services. The system provides accurate, timely federal agency information to colleges, universities, and other research organizations. There are no registration fees or access charges. Participating agencies include DOE, FAA, NASA, ONR, AFOSR, NSF, NSA, DOE, DOEd, HUD, and AID. This guide is intended to help users access and utilize FEDIX.

Blunted stress reactivity in chronic cannabis users.

PubMed

Cuttler, Carrie; Spradlin, Alexander; Nusbaum, Amy T; Whitney, Paul; Hinson, John M; McLaughlin, Ryan J

2017-08-01

One of the most commonly cited reasons for chronic cannabis use is to cope with stress. Consistent with this, cannabis users have shown reduced emotional arousal and dampened stress reactivity in response to negative imagery. To our knowledge, the present study represents the first to examine the effects of an acute stress manipulation on subjective stress and salivary cortisol in chronic cannabis users compared to non-users. Forty cannabis users and 42 non-users were randomly assigned to complete either the stress or no stress conditions of the Maastricht Acute Stress Test (MAST). The stress condition of the MAST manipulates both physiological (placing hand in ice bath) and psychosocial stress (performing math under conditions of social evaluation). Participants gave baseline subjective stress ratings before, during, and after the stress manipulation. Cortisol was measured from saliva samples obtained before and after the stress manipulation. Further, cannabis cravings and symptoms of withdrawal were measured. Subjective stress ratings and cortisol levels were significantly higher in non-users in the stress condition relative to non-users in the no stress condition. In contrast, cannabis users demonstrated blunted stress reactivity; specifically, they showed no increase in cortisol and a significantly smaller increase in subjective stress ratings. The stress manipulation had no impact on cannabis users' self-reported cravings or withdrawal symptoms. Chronic cannabis use is associated with blunted stress reactivity. Future research is needed to determine whether this helps to confer resiliency or vulnerability to stress-related psychopathology as well as the mechanisms underlying this effect.

The Mediating Roles of Upward Social Comparison and Self-esteem and the Moderating Role of Social Comparison Orientation in the Association between Social Networking Site Usage and Subjective Well-Being.

PubMed

Wang, Jin-Liang; Wang, Hai-Zhen; Gaskin, James; Hawk, Skyler

2017-01-01

The increased pervasiveness of social media use has raised questions about potential effects on users' subjective well-being, with studies reaching contrasting conclusions. To reconcile these discrepancies and shed new light on this phenomenon, the current study examined: (1) whether upward social comparison and self-esteem mediate the association between social networking site (SNS) usage and users' subjective well-being, and (2) whether the association between SNS usage and upward social comparison is moderated by users' social comparison orientation. Data from 696 participants were collected. Structural equation modeling revealed that upward social comparison and self-esteem mediated the relationship between SNS usage and users' subjective well-being. We found that social comparison orientation moderated the association between passive SNS usage and users' upward social comparison. Specifically, social comparison orientation strengthened the association between passive SNS usage and upward social comparison. The results might suggest a process through which passive SNS usage is related to subjective well-being, and identify a context under which these associations may differ.

VAGUE: a graphical user interface for the Velvet assembler.

PubMed

Powell, David R; Seemann, Torsten

2013-01-15

Velvet is a popular open-source de novo genome assembly software tool, which is run from the Unix command line. Most of the problems experienced by new users of Velvet revolve around constructing syntactically and semantically correct command lines, getting input files into acceptable formats and assessing the output. Here, we present Velvet Assembler Graphical User Environment (VAGUE), a multi-platform graphical front-end for Velvet. VAGUE aims to make sequence assembly accessible to a wider audience and to facilitate better usage amongst existing users of Velvet. VAGUE is implemented in JRuby and targets the Java Virtual Machine. It is available under an open-source GPLv2 licence from http://www.vicbioinformatics.com/. torsten.seemann@monash.edu.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barnette, Daniel W.

eCo-PylotDB, written completely in Python, provides a script that parses incoming emails and prepares extracted data for submission to a database table. The script extracts the database server, the database table, the server password, and the server username all from the email address to which the email is sent. The database table is specified on the Subject line. Any text in the body of the email is extracted as user comments for the database table. Attached files are extracted as data files with each file submitted to a specified table field but in separate rows of the targeted database table.more » Other information such as sender, date, time, and machine from which the email was sent is extracted and submitted to the database table as well. An email is sent back to the user specifying whether the data from the initial email was accepted or rejected by the database server. If rejected, the return email includes details as to why.« less

Braille line using electrical stimulation

NASA Astrophysics Data System (ADS)

Puertas, A.; Purés, P.; Echenique, A. M.; Ensinck, J. P. Graffigna y. G.

2007-11-01

Conceived within the field of Rehabilitation Technologies for visually impaired persons, the present work aims at enabling the blind user to read written material by means of a tactile display. Once he is familiarized to operate this system, the user will be able to achieve greater performance in study, academic and job activities, thus achieving a rapid and easier social inclusion. The devise accepts any kind of text that is computer-loadable (documents, books, Internet information, and the like) which, through digital means, can be read as Braille text on the pad. This tactile display is composed of an electrodes platform that simulate, through stimulation the writing/reading Braille characters. In order to perceive said characters in similar way to the tactile feeling from paper material, the skin receptor of fingers are stimulated electrically so as to simulate the same pressure and depressions as those of the paper-based counterpart information. Once designed and developed, the display was tested with blind subjects, with relatively satisfactory results. As a continuing project, this prototype is currently being improved as regards.

Gnuastro: GNU Astronomy Utilities

NASA Astrophysics Data System (ADS)

Akhlaghi, Mohammad

2018-01-01

Gnuastro (GNU Astronomy Utilities) manipulates and analyzes astronomical data. It is an official GNU package of a large collection of programs and C/C++ library functions. Command-line programs perform arithmetic operations on images, convert FITS images to common types like JPG or PDF, convolve an image with a given kernel or matching of kernels, perform cosmological calculations, crop parts of large images (possibly in multiple files), manipulate FITS extensions and keywords, and perform statistical operations. In addition, it contains programs to make catalogs from detection maps, add noise, make mock profiles with a variety of radial functions using monte-carlo integration for their centers, match catalogs, and detect objects in an image among many other operations. The command-line programs share the same basic command-line user interface for the comfort of both the users and developers. Gnuastro is written to comply fully with the GNU coding standards and integrates well with all Unix-like operating systems. This enables astronomers to expect a fully familiar experience in the source code, building, installing and command-line user interaction that they have seen in all the other GNU software that they use. Gnuastro's extensive library is included for users who want to build their own unique programs.

Effects of methylphenidate during emotional processing in amphetamine users: preliminary findings.

PubMed

Bottelier, M A; Schouw, M L J; de Ruiter, M B; Ruhe, H G; Lindauer, R J L; Reneman, L

2015-12-01

D-amphetamine (dAMPH) and methylphenidate (MPH) are stimulants used in the treatment of Attention Deficit Hyperactivity Disorder (ADHD). Preclinical studies have shown that in healthy animals, dAMPH induces dopamine (DA) dysfunction, as evidenced for instance by loss of DA levels and its transporters. It has also been suggested that DA plays an important role in emotional processing, and that altered DA-ergic intervention may modulate amygdala function. To explore the role of the DA system in emotional processing we examined emotional processing using functional magnetic resonance imaging (fMRI) in eight male recreational users of dAMPH and eight male healthy controls. We compared brain activation between both groups during an emotional face-processing task with and without an oral MPH challenge. All subjects were abstinent for at least 2 weeks during the baseline scan. The second scan was performed on the same day 1½ hours after receiving an oral dose of 35 mg MPH. A significant Valence*Group interaction (p = .037) indicated amygdala hyperreactivity to fearful facial expressions in dAMPH users that was robust against adjustment for age (p = .015). Furthermore, duration of amphetamine use in years was positively correlated with amygdala reactivity in dAMPH users (r = .76; p = .029). These exploratory findings are in line with previous findings suggesting that DA plays a role in emotional processing.

The AstroVR Collaboratory, an On-line Multi-User Environment for Research in Astrophysics

NASA Astrophysics Data System (ADS)

van Buren, D.; Curtis, P.; Nichols, D. A.; Brundage, M.

We describe our experiment with an on-line collaborative environment where users share the execution of programs and communicate via audio, video, and typed text. Collaborative environments represent the next step in computer-mediated conferencing, combining powerful compute engines, data persistence, shared applications, and teleconferencing tools. As proof of concept, we have implemented a shared image analysis tool, allowing geographically distinct users to analyze FITS images together. We anticipate that \\htmllink{AstroVR}{http://astrovr.ipac.caltech.edu:8888} and similar systems will become an important part of collaborative work in the next decade, including with applications in remote observing, spacecraft operations, on-line meetings, as well as and day-to-day research activities. The technology is generic and promises to find uses in business, medicine, government, and education.

Prefrontal N-acetylaspartate is strongly associated with memory performance in (abstinent) ecstasy users: preliminary report.

PubMed

Reneman, L; Majoie, C B; Schmand, B; van den Brink, W; den Heeten, G J

2001-10-01

3,4-methylenedioxymethamphetamine (MDMA or "Ecstasy") is known to damage brain serotonin neurons in animals and possibly humans. Because serotonergic damage may adversely affect memory, we compared verbal memory function between MDMA users and MDMA-naïve control subjects and evaluated the relationship between verbal memory function and neuronal dysfunction in the MDMA users. An auditory verbal memory task (Rey Auditory Verbal Learning Test) was used to study eight abstinent MDMA users and seven control subjects. In addition 1H-MRS was used in different brain regions of all MDMA users to measure N-acetylaspartate/creatine (NAA/Cr) ratios, a marker for neuronal viability. The MDMA users recalled significantly fewer words than control subjects on delayed (p =.03) but not immediate recall (p =.08). In MDMA users, delayed memory function was strongly associated with NAA/Cr only in the prefrontal cortex (R(2) =.76, p =.01). Greater decrements in memory function predicted lower NAA/Cr levels-and by inference greater neuronal dysfunction-in the prefrontal cortex of MDMA users.

A Quantitative Risk Assessment Model Involving Frequency and Threat Degree under Line-of-Business Services for Infrastructure of Emerging Sensor Networks.

PubMed

Jing, Xu; Hu, Hanwen; Yang, Huijun; Au, Man Ho; Li, Shuqin; Xiong, Naixue; Imran, Muhammad; Vasilakos, Athanasios V

2017-03-21

The prospect of Line-of-Business Services (LoBSs) for infrastructure of Emerging Sensor Networks (ESNs) is exciting. Access control remains a top challenge in this scenario as the service provider's server contains a lot of valuable resources. LoBSs' users are very diverse as they may come from a wide range of locations with vastly different characteristics. Cost of joining could be low and in many cases, intruders are eligible users conducting malicious actions. As a result, user access should be adjusted dynamically. Assessing LoBSs' risk dynamically based on both frequency and threat degree of malicious operations is therefore necessary. In this paper, we proposed a Quantitative Risk Assessment Model (QRAM) involving frequency and threat degree based on value at risk. To quantify the threat degree as an elementary intrusion effort, we amend the influence coefficient of risk indexes in the network security situation assessment model. To quantify threat frequency as intrusion trace effort, we make use of multiple behavior information fusion. Under the influence of intrusion trace, we adapt the historical simulation method of value at risk to dynamically access LoBSs' risk. Simulation based on existing data is used to select appropriate parameters for QRAM. Our simulation results show that the duration influence on elementary intrusion effort is reasonable when the normalized parameter is 1000. Likewise, the time window of intrusion trace and the weight between objective risk and subjective risk can be set to 10 s and 0.5, respectively. While our focus is to develop QRAM for assessing the risk of LoBSs for infrastructure of ESNs dynamically involving frequency and threat degree, we believe it is also appropriate for other scenarios in cloud computing.

A Quantitative Risk Assessment Model Involving Frequency and Threat Degree under Line-of-Business Services for Infrastructure of Emerging Sensor Networks

PubMed Central

Jing, Xu; Hu, Hanwen; Yang, Huijun; Au, Man Ho; Li, Shuqin; Xiong, Naixue; Imran, Muhammad; Vasilakos, Athanasios V.

2017-01-01

The prospect of Line-of-Business Services (LoBSs) for infrastructure of Emerging Sensor Networks (ESNs) is exciting. Access control remains a top challenge in this scenario as the service provider’s server contains a lot of valuable resources. LoBSs’ users are very diverse as they may come from a wide range of locations with vastly different characteristics. Cost of joining could be low and in many cases, intruders are eligible users conducting malicious actions. As a result, user access should be adjusted dynamically. Assessing LoBSs’ risk dynamically based on both frequency and threat degree of malicious operations is therefore necessary. In this paper, we proposed a Quantitative Risk Assessment Model (QRAM) involving frequency and threat degree based on value at risk. To quantify the threat degree as an elementary intrusion effort, we amend the influence coefficient of risk indexes in the network security situation assessment model. To quantify threat frequency as intrusion trace effort, we make use of multiple behavior information fusion. Under the influence of intrusion trace, we adapt the historical simulation method of value at risk to dynamically access LoBSs’ risk. Simulation based on existing data is used to select appropriate parameters for QRAM. Our simulation results show that the duration influence on elementary intrusion effort is reasonable when the normalized parameter is 1000. Likewise, the time window of intrusion trace and the weight between objective risk and subjective risk can be set to 10 s and 0.5, respectively. While our focus is to develop QRAM for assessing the risk of LoBSs for infrastructure of ESNs dynamically involving frequency and threat degree, we believe it is also appropriate for other scenarios in cloud computing. PMID:28335569

Subject Access Problems of Different Types of OPAC Users Or, the Double Challenge.

ERIC Educational Resources Information Center

Cochrane, Pauline A.

1989-01-01

Reviews the problems of users of online public access catalogs and argues that it is necessary to think of all searching problems as systems problems rather than user failures, and to concentrate research in the area of systems enhancements. A list of improved tools needed for subject searching in online catalogs is identified. (CLB)

Spatial working memory in heavy cannabis users: a functional magnetic resonance imaging study.

PubMed

Kanayama, Gen; Rogowska, Jadwiga; Pope, Harrison G; Gruber, Staci A; Yurgelun-Todd, Deborah A

2004-11-01

Many neuropsychological studies have documented deficits in working memory among recent heavy cannabis users. However, little is known about the effects of cannabis on brain activity. We assessed brain function among recent heavy cannabis users while they performed a working memory task. Functional magnetic resonance imaging was used to examine brain activity in 12 long-term heavy cannabis users, 6-36 h after last use, and in 10 control subjects while they performed a spatial working memory task. Regional brain activation was analyzed and compared using statistical parametric mapping techniques. Compared with controls, cannabis users exhibited increased activation of brain regions typically used for spatial working memory tasks (such as prefrontal cortex and anterior cingulate). Users also recruited additional regions not typically used for spatial working memory (such as regions in the basal ganglia). These findings remained essentially unchanged when re-analyzed using subjects' ages as a covariate. Brain activation showed little or no significant correlation with subjects' years of education, verbal IQ, lifetime episodes of cannabis use, or urinary cannabinoid levels at the time of scanning. Recent cannabis users displayed greater and more widespread brain activation than normal subjects when attempting to perform a spatial working memory task. This observation suggests that recent cannabis users may experience subtle neurophysiological deficits, and that they compensate for these deficits by "working harder"-calling upon additional brain regions to meet the demands of the task.

NEQAIR96,Nonequilibrium and Equilibrium Radiative Transport and Spectra Program: User's Manual

NASA Technical Reports Server (NTRS)

Whiting, Ellis E.; Park, Chul; Liu, Yen; Arnold, James O.; Paterson, John A.

1996-01-01

This document is the User's Manual for a new version of the NEQAIR computer program, NEQAIR96. The program is a line-by-line and a line-of-sight code. It calculates the emission and absorption spectra for atomic and diatomic molecules and the transport of radiation through a nonuniform gas mixture to a surface. The program has been rewritten to make it easy to use, run faster, and include many run-time options that tailor a calculation to the user's requirements. The accuracy and capability have also been improved by including the rotational Hamiltonian matrix formalism for calculating rotational energy levels and Hoenl-London factors for dipole and spin-allowed singlet, doublet, triplet, and quartet transitions. Three sample cases are also included to help the user become familiar with the steps taken to produce a spectrum. A new user interface is included that uses check location, to select run-time options and to enter selected run data, making NEQAIR96 easier to use than the older versions of the code. The ease of its use and the speed of its algorithms make NEQAIR96 a valuable educational code as well as a practical spectroscopic prediction and diagnostic code.

The New Web-Based Hera Data Processing System at the HEASARC

NASA Technical Reports Server (NTRS)

Pence, W.

2011-01-01

The HEASARC at NASA/GSFC has provide an on-line astronomical data processing system called Hera for several years. Hera provides a complete data processing environment, including installed software packages, local data storage, and the CPU resources needed to process the user's data. The original design of Hera, however, has 2 requirements that has limited it's usefulness for some users, namely, that 1) the user must download and install a small helper program on their own computer before using Hera, and 2) Hera requires that several computer ports/sockets be allowed to communicate through any local firewalls on the users machine. Both of these restrictions can be problematic for some users, therefore we are now migrating Hera into a purely Web based environment which only requires a standard Web browser. The first release of Web Hera is now publicly available at http://heasarc.gsfc.nasa.gov/webheara/. It currently provides a standard graphical interface for running hundreds of different data processing programs that are available in the HEASARC's ftools software package. Over the next year we to add more features to Web Hera, including an interactive command line interface, and more display and line capabilities.

Easing access to R using 'shiny' to create graphical user interfaces: An example for the R package 'Luminescence'

NASA Astrophysics Data System (ADS)

Burow, Christoph; Kreutzer, Sebastian; Dietze, Michael; Fuchs, Margret C.; Schmidt, Christoph; Fischer, Manfred; Brückner, Helmut

2017-04-01

Since the release of the R package 'Luminescence' (Kreutzer et al., 2012) the functionality of the package has been greatly enhanced by implementing further functions for measurement data processing, statistical analysis and graphical output. Despite its capabilities for complex and non-standard analysis of luminescence data, working with the command-line interface (CLI) of R can be tedious at best and overwhelming at worst, especially for users without experience in programming languages. Even though much work is put into simplifying the usage of the package to continuously lower the entry threshold, at least basic knowledge of R will always be required. Thus, the potential user base of the package cannot be exhausted, at least as long as the CLI is the only means of utilising the 'Luminescence' package. But even experienced users may find it tedious to iteratively run a function until a satisfying results is produced. For example, plotting data is also at least partly subject to personal aesthetic tastes in accordance with the information it is supposed to convey and iterating through all the possible options in the R CLI can be a time-consuming task. An alternative approach to the CLI is the graphical user interface (GUI), which allows direct, interactive manipulation and interaction with the underlying software. For users with little or no experience with command-lines a GUI offers intuitive access that counteracts the perceived steep learning curve of a CLI. Even though R lacks native support for GUI functions, its capabilities of linking it to other programming languages allows to utilise external frameworks to build graphical user interfaces. A recent attempt to provide a GUI toolkit for R was the introduction of the 'shiny' package (Chang et al., 2016), which allows automatic construction of HTML, CSS and JavaScript based user interfaces straight from R. Here, we give (1) a brief introduction to the 'shiny' framework for R, before we (2) present a GUI for the R package 'Luminescence' in the form of interactive web applications. These applications can be accessed online so that a user is not even required to have a local installation of R and which provide access to most of the plotting functions of the R package 'Luminescence'. These functionalities will be demonstrated live during the PICO session. References Chang, W., Cheng, J., Allaire, JJ., Xie, Y., McPherson, J., 2016. shiny: Web Application Framework for R. R package version 0.13.2. https://CRAN.R-project.org/package=shiny Kreutzer, S., Schmidt, C., Fuchs, M.C., Dietze, M., Fischer, M., Fuchs, M., 2012. Introducing an R package for luminescence dating analysis. Ancient TL, 30: 1-8, 2012.

An automatic calibration procedure for remote eye-gaze tracking systems.

PubMed

Model, Dmitri; Guestrin, Elias D; Eizenman, Moshe

2009-01-01

Remote gaze estimation systems use calibration procedures to estimate subject-specific parameters that are needed for the calculation of the point-of-gaze. In these procedures, subjects are required to fixate on a specific point or points at specific time instances. Advanced remote gaze estimation systems can estimate the optical axis of the eye without any personal calibration procedure, but use a single calibration point to estimate the angle between the optical axis and the visual axis (line-of-sight). This paper presents a novel automatic calibration procedure that does not require active user participation. To estimate the angles between the optical and visual axes of each eye, this procedure minimizes the distance between the intersections of the visual axes of the left and right eyes with the surface of a display while subjects look naturally at the display (e.g., watching a video clip). Simulation results demonstrate that the performance of the algorithm improves as the range of viewing angles increases. For a subject sitting 75 cm in front of an 80 cm x 60 cm display (40" TV) the standard deviation of the error in the estimation of the angles between the optical and visual axes is 0.5 degrees.

Medication Use, Falls, and Fall-Related Worry in Older Adults in the United States.

PubMed

Watanabe, Jonathan H

2016-07-01

To compare the prevalence of falls and fall-related concerns of medication users versus nonusers in U.S. seniors. Cross-sectional study. The National Health and Aging Trends Study. U.S. nationally representative sample of Medicare beneficiaries in 2011. Comparing subjects who used medications with subjects who did not in the past month, the outcomes were percentages of subjects who experienced 1) a fall in the past month, 2) worry about falling in the past month, 3) being limited by this worry in the past month, 4) a fall in the past year. A greater percentage of medication users experienced falls and fall-related outcomes, compared with non-medication users. Among medication users, 10.29% had a past month fall, compared with 5.42% of non-medication users; 27.69% of medication users worried in the past month about falling, compared with 9.15% of non-medication users; 40.96% of medication users were limited by this worry, compared with 21.21%; 22.82% of medication users had a fall in the past year, compared with 13.15% of non-medication users. Seniors who use medications are more likely to fall and to be concerned about falling. Pharmacist involvement in fall prevention continues to be essential.

Library Subject Guides: A Case Study of Evidence-Informed Library Development

ERIC Educational Resources Information Center

Wakeham, Maurice; Roberts, Angharad; Shelley, Jane; Wells, Paul

2012-01-01

This paper describes the process whereby a university library investigated the value of its subject guides to its users. A literature review and surveys of library staff, library users and other libraries were carried out. Existing library subject guides and those of other higher education libraries were evaluated. The project team reported…

Innovation & evaluation of tangible direct manipulation digital drawing pens for children.

PubMed

Lee, Tai-Hua; Wu, Fong-Gong; Chen, Huei-Tsz

2017-04-01

Focusing on the theme of direct manipulation, in this study, we proposed a new and innovative tangible user interface (TUI) design concept for a manipulative digital drawing pen. Based on interviews with focus groups brainstorming and experts and the results of a field survey, we selected the most suitable tangible user interface for children between 4 and 7 years of age. Using the new tangible user interface, children could choose between the brush tools after touching and feeling the various patterns. The thickness of the brush could be adjusted by changing the tilt angle. In a subsequent experimental process we compared the differences in performance and subjective user satisfaction. A total of sixteen children, aged 4-7 years participated in the experiment. Two operating system experiments (the new designed tangible digital drawing pen and traditional visual interface-icon-clicking digital drawing pens) were performed at random and in turns. We assessed their manipulation performance, accuracy, brush stroke richness and subjective evaluations. During the experimental process we found that operating functions using the direct manipulation method, and adding shapes and semantic models to explain the purpose of each function, enabled the children to perform stroke switches relatively smoothly. By using direct manipulation digital pens, the children could improve their stroke-switching performance for digital drawing. Additionally, by using various patterns to represent different brushes or tools, the children were able to make selections using their sense of touch, thereby reducing the time required to move along the drawing pens and select icons (The significant differences (p = 0.000, p < 0.01) existed in the manipulation times for drawing thick lines using the crayon function of the two (new and old) drawing pens (new 5.8750 < old 10.7500)). The addition of direct manipulation movements to drawing operations enhanced the drawing results, thereby increasing the children's enjoyment of drawing with tangible digital drawing pens. Copyright © 2016 Elsevier Ltd. All rights reserved.

SU-F-T-80: A Mobile Application for Intra-Operative Electron Radiotherapy Treatment Planning

DOE Office of Scientific and Technical Information (OSTI.GOV)

Williams, C; Harvard Medical School, Boston, MA; Crowley, E

Purpose: Intraoperative electron radiotherapy (IORT) poses a unique set of challenges for treatment planning. Planning must be performed in a busy operating room environment over a short timeframe often with little advance knowledge of the treatment depth or applicator size. Furthermore, IORT accelerators can have a large number of possible applicators, requiring extensive databooks that must be searched for the appropriate dosimetric parameters. The goal of this work is to develop a software tool to assist in the planning process that is suited to the challenges faced in the IORT environment. Methods: We developed a mobile application using HTML5 andmore » Javascript that can be deployed to tablet devices suitable for use in the operating room. The user selects the desired treatment parameters cone diameter, bevel angle, and energy (a total of 141 datasets) and desired bolus. The application generates an interactive display that allows the user to dynamically select points on the depth-dose curve and to visualize the shape of the corresponding isodose contours. The user can indicate a prescription isodose line or depth. The software performs a monitor unit calculation and generates a PDF report. Results: We present our application, which is now used routinely in our IORT practice. It has been employed successfully in over 23 cases. The interactivity of the isodose distributions was found to be of particular use to physicians who are less-frequent IORT users, as well as for the education of residents and trainees. Conclusion: This software has served as a useful tool in IORT planning, and demonstrates the need for treatment planning tools that are designed for the specialized challenges encountered in IORT. This software is the subject of a license agreement with the IntraOp Medical Corporation. This software is the subject of a license agreement between Massachusetts General Hospital / Partners Healthcare and the IntraOp Medical Corporation. CLW is consulting on software development with the IntraOp Medical Corporation.« less

Introduction to TAFI - A Matlab® toolbox for analysis of flexural isostasy

NASA Astrophysics Data System (ADS)

Jha, S.; Harry, D. L.; Schutt, D.

2016-12-01

The isostatic response of vertical tectonic loads emplaced on thin elastic plates overlying inviscid substrate and the corresponding gravity anomalies are commonly modeled using well established theories and methodologies of flexural analysis. However, such analysis requires some mathematical and coding expertise on part of users. With that in mind, we designed a new interactive Matlab® toolbox called Toolbox for Analysis of Flexural Isostasy (TAFI). TAFI allows users to create forward models (2-D and 3-D) of flexural deformation of the lithosphere and resulting gravity anomaly. TAFI computes Green's Functions for flexure of the elastic plate subjected to point or line loads, and analytical solution for harmonic loads. Flexure due to non-impulsive, distributed 2-D or 3-D loads are computed by convolving the appropriate Green's function with a user-supplied spatially discretized load function. The gravity anomaly associated with each density interface is calculated by using the Fourier Transform of flexural deflection of these interfaces and estimating the gravity in the wavenumber domain. All models created in TAFI are based on Matlab's intrinsic functions and do not require any specialized toolbox, function or library except those distributed with TAFI. Modeling functions within TAFI can be called from Matlab workspace, from within user written programs or from the TAFI's graphical user interface (GUI). The GUI enables the user to model the flexural deflection of lithosphere interactively, enabling real time comparison of model fit with observed data constraining the flexural deformation and gravity, facilitating rapid search for best fitting flexural model. TAFI is a very useful teaching and research tool and have been tested rigorously in graduate level teaching and basic research environment.

Usability Testing, User-Centered Design, and LibGuides Subject Guides: A Case Study

ERIC Educational Resources Information Center

Sonsteby, Alec; DeJonghe, Jennifer

2013-01-01

Usability testing has become a routine way for many libraries to ensure that their Web presence is user-friendly and accessible. At the same time, popular subject guide creation systems, such as LibGuides, decentralize Web content creation and put authorship into the hands of librarians who may not be trained in user-centered design principles. At…

The User Interface of ERIC on the Macintosh: A Qualitative Study of Novice Users.

ERIC Educational Resources Information Center

Thomas, Patricia

The experience of novice users searching SilverPlatter's ERIC CD-ROM on the Macintosh was studied. Ten students from an introductory master's level course in library and information science were recruited as volunteer subjects. Subjects were asked to complete a search on the ERIC CD-ROM; and data were collected via observations, a think-aloud…

Geoethical and socio-political aspects of seismic and tsunami hazard assessment, quantification and mapping

NASA Astrophysics Data System (ADS)

Tinti, Stefano; Armigliato, Alberto

2016-04-01

Seismic hazard and, more recently, tsunami hazard assessments have been undertaken in several countries of the world and globally for the whole Earth planet with the aim of providing a scientifically sound basis to the engineers, technicians, urban and industrial planners, politicians, civil protection operators and in general to the authorities for devising rational risk mitigation strategies and corresponding adequate policies. The main point of this presentation is that the chief-value of all seismic and tsunami hazard studies (including theory, concept, quantification and mapping) resides in the social and political values of the provided products, which is a standpoint entailing a number of relevant geoethical implications. The most relevant implication regards geoscientists who are the subjects mainly involved in carrying out hazard evaluations. Viewed from the classical perspective, the main ethical obligations of geoscientists are restricted to performing hazard estimations in the best possible way from a scientific point of view, which means selecting the "best" available data, adopting sound theoretical models, making use of rigorous methods… What is outlined here, is that this is an insufficient minimalistic position, since it overlooks the basic socio-political and therefore practical value of the hazard-analysis final products. In other words, if one views hazard assessment as a production process leading from data and theories (raw data and production means) to hazard maps (products), the criterion to judge whether it is good or bad needs also to include the usability factor. Seismic and tsunami hazard reports and maps are products that should be usable, which means that they should meet user needs and requirements, and therefore they should be evaluated according to how much they are clearly understandable to, and appropriate for, making-decision users. In the traditional view of a science serving the society, one could represent the interaction process as a line connecting geoscientists and users, where geoscientists possess the knowledge (data, theory and models) and teach, while users get products and learn. The new geoethical perspective is that the line is replaced by a loop, where geoscientists and users interact cyclically: 1) where theory and methods themselves are not determined a-priori, but they result also in response of geoscientists-users interactions, and 2) where user needs can be modified ex-post in response to geoscientists elaborations. These two-way feedback actions, opening also the path to close interdisciplinary approaches involving geo- and social sciences, are the main challenge for the present generation of geoscientists. Unfortunately they are not properly and adequately reflected in the today university educational systems, and in professional societies.

Differential effects of tamoxifen and anastrozole on optic cup size in breast cancer survivors

PubMed Central

Toomey, Maureen D.; Falardeau, Julie; Samples, John R.; Vetto, John T.

2007-01-01

Introduction The main purpose of this study was to determine whether the optic cups of tamoxifen users and anastrozole users differ in size, with the cups of the tamoxifen users being smaller. Methods Optic nerve head (ONH) topography was measured using a commercially available, confocal scanning laser ophthalmoscope for three populations of amenorrheic women ages 40–69 years: subjects using (1) tamoxifen (20 mg/day) or (2) anastrozole (1 mg/day) for ≤ 2 years as adjuvant therapy after successful primary treatment for breast cancer, and (3) control subjects with no breast cancer histories and not using any hormonal medication. All subjects had excellent visual acuity and healthy eyes, based on conventional photographic assessment. Results The cup volumes of the tamoxifen users were shown to be significantly smaller than the cup volumes of the anastrozole users, which were indistinguishable from normal. Because the cup volumes of the tamoxifen users decreased markedly with age at about 50 years and because anastrozole is indicated only for post-menopausal women, comparisons were reassessed for subjects older than 50 years. For these subjects, the cup volumes of the tamoxifen users averaged less than half of the volumes for each of the other two subject groups, and significant between-group differences existed in both the lateral (cup area) and axial (cup depth) directions. In contrast, any between-group differences at the ONH margin were small and not significant. Conclusions The results of this study suggest that the ONH be assessed biomorphometrically for tamoxifen users reporting visual change that cannot be attributed to non-tamoxifen causes. The ability of modern intraocular imaging techniques to reveal anatomic change on the order of tens of microns may be useful for assessing tamoxifen-induced effects occurring simultaneously elsewhere in the brain, particularly since the presence of small cups is consistent with the possibility of tamoxifen-induced astrocytic swelling. PMID:17260092

User-centered design of quality of life reports for clinical care of patients with prostate cancer

PubMed Central

Izard, Jason; Hartzler, Andrea; Avery, Daniel I.; Shih, Cheryl; Dalkin, Bruce L.; Gore, John L.

2014-01-01

Background Primary treatment of localized prostate cancer can result in bothersome urinary, sexual, and bowel symptoms. Yet clinical application of health-related quality-of-life (HRQOL) questionnaires is rare. We employed user-centered design to develop graphic dashboards of questionnaire responses from patients with prostate cancer to facilitate clinical integration of HRQOL measurement. Methods We interviewed 50 prostate cancer patients and 50 providers, assessed literacy with validated instruments (Rapid Estimate of Adult Literacy in Medicine short form, Subjective Numeracy Scale, Graphical Literacy Scale), and presented participants with prototype dashboards that display prostate cancer-specific HRQOL with graphic elements derived from patient focus groups. We assessed dashboard comprehension and preferences in table, bar, line, and pictograph formats with patient scores contextualized with HRQOL scores of similar patients serving as a comparison group. Results Health literacy (mean score, 6.8/7) and numeracy (mean score, 4.5/6) of patient participants was high. Patients favored the bar chart (mean rank, 1.8 [P = .12] vs line graph [P <.01] vs table and pictograph); providers demonstrated similar preference for table, bar, and line formats (ranked first by 30%, 34%, and 34% of providers, respectively). Providers expressed unsolicited concerns over presentation of comparison group scores (n = 19; 38%) and impact on clinic efficiency (n = 16; 32%). Conclusion Based on preferences of prostate cancer patients and providers, we developed the design concept of a dynamic HRQOL dashboard that permits a base patient-centered report in bar chart format that can be toggled to other formats and include error bars that frame comparison group scores. Inclusion of lower literacy patients may yield different preferences. PMID:24787105

User-centered design of quality of life reports for clinical care of patients with prostate cancer.

PubMed

Izard, Jason; Hartzler, Andrea; Avery, Daniel I; Shih, Cheryl; Dalkin, Bruce L; Gore, John L

2014-05-01

Primary treatment of localized prostate cancer can result in bothersome urinary, sexual, and bowel symptoms. Yet clinical application of health-related quality-of-life (HRQOL) questionnaires is rare. We employed user-centered design to develop graphic dashboards of questionnaire responses from patients with prostate cancer to facilitate clinical integration of HRQOL measurement. We interviewed 50 prostate cancer patients and 50 providers, assessed literacy with validated instruments (Rapid Estimate of Adult Literacy in Medicine short form, Subjective Numeracy Scale, Graphical Literacy Scale), and presented participants with prototype dashboards that display prostate cancer-specific HRQOL with graphic elements derived from patient focus groups. We assessed dashboard comprehension and preferences in table, bar, line, and pictograph formats with patient scores contextualized with HRQOL scores of similar patients serving as a comparison group. Health literacy (mean score, 6.8/7) and numeracy (mean score, 4.5/6) of patient participants was high. Patients favored the bar chart (mean rank, 1.8 [P = .12] vs line graph [P < .01] vs table and pictograph); providers demonstrated similar preference for table, bar, and line formats (ranked first by 30%, 34%, and 34% of providers, respectively). Providers expressed unsolicited concerns over presentation of comparison group scores (n = 19; 38%) and impact on clinic efficiency (n = 16; 32%). Based on preferences of prostate cancer patients and providers, we developed the design concept of a dynamic HRQOL dashboard that permits a base patient-centered report in bar chart format that can be toggled to other formats and include error bars that frame comparison group scores. Inclusion of lower literacy patients may yield different preferences. Copyright © 2014 Mosby, Inc. All rights reserved.

Discovering Black Soap: A Survey on the Attitudes and Practices of Black Soap Users.

PubMed

Lin, Ann; Nabatian, Adam; Halverstam, Caroline P

2017-07-01

OBJECTIVE: The purpose of this study was to discover the general attitudes and practices of black soap users with regard to amelioration of various dermatologic conditions. DESIGN: This was a prospective questionnaire-based study with a sample size of 100 black soap users. Setting: Outpatient dermatology clinics of Montefiore Medical Center and other Albert Einstein affiliated dermatology clinics in Bronx, New York. PARTICIPANTS: One hundred subjects who have used black soap were recruited. MEASUREMENTS: The participants evaluated and reported their attitudes and applications of black soap. Data on sociodemographic prevalence and user satisfactions of black soap were collected and analyzed. RESULTS: The age distribution of participants was uniform among the specified age categories: 1) 18 to 29 years; 2) 30 to 39 years, 3) 40 to 49 yesars, and 4) 50 years and older. The sex distribution favored women, comprising 74 percent of those surveyed. A significant number of participants were born in either Africa (23%) or the Caribbean (19%). Black soap usage was applied to mitigate many dermatologic conditions, including acne (23%), dark spots (20%), razor bumps (13%), eczema (7%), and fine lines (4%). The most popular usage was for overall skin care (70%). The vast majority of users found black soap helpful for their skin condition (51% very satisfied, and 40% somewhat satisfied). Conclusion: The survey results indicate widespread usage and satisfaction with black soap for reduction in symptoms of various dermatologic conditions. Further investigations are warranted to discover active ingredients present in black soap that may unveil future therapeutic options for various dermatologic conditions.

Effects of galvanic skin response feedback on user experience in gaze-controlled gaming: A pilot study.

PubMed

Larradet, Fanny; Barresi, Giacinto; Mattos, Leonardo S

2017-07-01

Eye-tracking (ET) is one of the most intuitive solutions for enabling people with severe motor impairments to control devices. Nevertheless, even such an effective assistive solution can detrimentally affect user experience during demanding tasks because of, for instance, the user's mental workload - using gaze-based controls for an extensive period of time can generate fatigue and cause frustration. Thus, it is necessary to design novel solutions for ET contexts able to improve the user experience, with particular attention to its aspects related to workload. In this paper, a pilot study evaluates the effects of a relaxation biofeedback system on the user experience in the context of a gaze-controlled task that is mentally and temporally demanding: ET-based gaming. Different aspects of the subjects' experience were investigated under two conditions of a gaze-controlled game. In the Biofeedback group (BF), the user triggered a command by means of voluntary relaxation, monitored through Galvanic Skin Response (GSR) and represented by visual feedback. In the No Biofeedback group (NBF), the same feedback was timed according to the average frequency of commands in BF. After the experiment, each subject filled out a user experience questionnaire. The results showed a general appreciation for BF, with a significant between-group difference in the perceived session time duration, with the latter being shorter for subjects in BF than for the ones in NBF. This result implies a lower mental workload for BF than for NBF subjects. Other results point toward a potential role of user's engagement in the improvement of user experience in BF. Such an effect highlights the value of relaxation biofeedback for improving the user experience in a demanding gaze-controlled task.

Robust changes in reward circuitry during reward loss in current and former cocaine users during performance of a monetary incentive delay task.

PubMed

Patel, Krishna T; Stevens, Michael C; Meda, Shashwath A; Muska, Christine; Thomas, Andre D; Potenza, Marc N; Pearlson, Godfrey D

2013-10-01

Abnormal function in reward circuitry in cocaine addiction could predate drug use as a risk factor, follow drug use as a consequence of substance-induced alterations, or both. We used a functional magnetic resonance imaging monetary incentive delay task (MIDT) to investigate reward-loss neural response differences among 42 current cocaine users, 35 former cocaine users, and 47 healthy subjects who also completed psychological measures and tasks related to impulsivity and reward. We found various reward processing-related group differences in several MIDT phases. Across task phases we found a control > current user > former user activation pattern, except for loss outcome, where former compared with current cocaine users activated ventral tegmental area more robustly. We also found regional prefrontal activation differences during loss anticipation between cocaine-using groups. Both groups of cocaine users scored higher than control subjects on impulsivity, compulsivity and reward-punishment sensitivity factors. In addition, impulsivity-related factors correlated positively with activation in amygdala and negatively with anterior cingulate activation during loss anticipation. Compared with healthy subjects, both former and current users displayed abnormal brain activation patterns during MIDT performance. Both cocaine groups differed similarly from healthy subjects, but differences between former and current users were localized to the ventral tegmental area during loss outcome and to prefrontal regions during loss anticipation, suggesting that long-term cocaine abstinence does not normalize most reward circuit abnormalities. Elevated impulsivity-related factors that relate to loss processing in current and former users suggest that these tendencies and relationships may pre-exist cocaine addiction. © 2013 Society of Biological Psychiatry.

Comparing subjective well-being and health-related quality of life of Australian drug users in treatment in regional and rural Victoria.

PubMed

Miller, Peter G; Hyder, Shannon; Zinkiewicz, Lucy; Droste, Nicolas; Harris, Jane B

2014-11-01

The aim of this study is to examine the self-reported subjective well-being and health-related quality of life (HRQOL) of alcohol and other drug users and to examine whether subjective well-being in this sample would be predicted by either HRQOL and/or severity of dependence. A cross-sectional survey was conducted of 201 Victorian substance users in individual targeted outpatient treatment for a variety of types of substance use. Participants were administered an interview, including the personal well-being index, the SF-8 health survey and the severity of dependence scale, in order to assess subjective well-being, the mental health component of HRQOL and severity of drug dependence respectively. Subjective well-being was predicted by mental health aspects of HRQOL (sr(2)  = 0.03) and by employment (sr(2)  = 0.05), rather than by severity of dependence [F(5, 146) = 5.60, P < 0.001, R(2)  = 0.14]. The current sample of urban and regional substance users in outpatient treatment shows poorer levels of subjective well-being than do the general population. Subjective well-being was predicted by mental aspects of HRQOL and not by severity of drug dependence or by physical aspects of HRQOL. Treatment which aims to improve substance users' well-being should include mental health interventions and pathways to employment. © 2014 Australasian Professional Society on Alcohol and other Drugs.

4-Fluoroamphetamine in the Netherlands: more than a one-night stand.

PubMed

Linsen, Felix; Koning, Raoul P J; van Laar, Margriet; Niesink, Raymond J M; Koeter, Maarten W; Brunt, Tibor M

2015-07-01

To investigate the temporal pattern of appearance of a new psychoactive substance (4-fluoroamphetamine) on the Dutch drug market, as well as its patterns of use and effects. Data from the Drug Information and Monitoring System (DIMS) was used to investigate the emergence of 4-fluoroamphetamine on the Dutch drug market. An on-line questionnaire was used to study its patterns of use and effects. Dutch drug-related websites and social media. A convenience sample of 249 life-time 4-fluoroamphetamine users was recruited through the internet. Samples containing 4-fluoroamphetamine were extracted from the DIMS database for further investigation. Patterns of use, settings of use and the subjective effects of 4-fluoroamphetamine, amphetamine and 3,4-methylenedioxymethamphetamine (MDMA) were investigated with the on-line questionnaire. 4-Fluoroamphetamine was first encountered on the Dutch drug market, sold mainly as amphetamine or ecstasy (MDMA), between 2007 and 2009. These misrepresented drug samples declined when the MDMA and amphetamine markets recovered after a period of shortage, whereas purposefully bought 4-fluoroamphetamine samples showed an increase. Survey results showed that 4-fluoroamphetamine is used predominantly [77.1%, 95% confidence interval (CI) = 72.0-82.3] for its specific effects, rather than its legal status (17.7%, 95% CI = 10.7-22.1). The subjective effects of 4-fluoroamphetamine were compared with those of amphetamine and MDMA. Subjective effect scores of 4-fluoroamphetamine ranged between those of amphetamine and MDMA. The stimulant 4-fluoroamphetamine is increasingly popular in the Netherlands, which might be due to its subjective effects profile, which lies intermediate between amphetamine and MDMA. © 2015 Society for the Study of Addiction.

Community LINE Source Model (C-LINE)

EPA Science Inventory

This presentation provides an introduction for the live demo and explains the purpose of C-LINE and its key features. C-LINE is a web-based model designed to inform the community user of local air quality impacts due to mobile-sources in their region of interest using a simplifie...

MAPA: an interactive accelerator design code with GUI

NASA Astrophysics Data System (ADS)

Bruhwiler, David L.; Cary, John R.; Shasharina, Svetlana G.

1999-06-01

The MAPA code is an interactive accelerator modeling and design tool with an X/Motif GUI. MAPA has been developed in C++ and makes full use of object-oriented features. We present an overview of its features and describe how users can independently extend the capabilities of the entire application, including the GUI. For example, a user can define a new model for a focusing or accelerating element. If the appropriate form is followed, and the new element is "registered" with a single line in the specified file, then the GUI will fully support this user-defined element type after it has been compiled and then linked to the existing application. In particular, the GUI will bring up windows for modifying any relevant parameters of the new element type. At present, one can use the GUI for phase space tracking, finding fixed points and generating line plots for the Twiss parameters, the dispersion and the accelerator geometry. The user can define new types of simulations which the GUI will automatically support by providing a menu option to execute the simulation and subsequently rendering line plots of the resulting data.

Normal probability plots with confidence.

PubMed

Chantarangsi, Wanpen; Liu, Wei; Bretz, Frank; Kiatsupaibul, Seksan; Hayter, Anthony J; Wan, Fang

2015-01-01

Normal probability plots are widely used as a statistical tool for assessing whether an observed simple random sample is drawn from a normally distributed population. The users, however, have to judge subjectively, if no objective rule is provided, whether the plotted points fall close to a straight line. In this paper, we focus on how a normal probability plot can be augmented by intervals for all the points so that, if the population distribution is normal, then all the points should fall into the corresponding intervals simultaneously with probability 1-α. These simultaneous 1-α probability intervals provide therefore an objective mean to judge whether the plotted points fall close to the straight line: the plotted points fall close to the straight line if and only if all the points fall into the corresponding intervals. The powers of several normal probability plot based (graphical) tests and the most popular nongraphical Anderson-Darling and Shapiro-Wilk tests are compared by simulation. Based on this comparison, recommendations are given in Section 3 on which graphical tests should be used in what circumstances. An example is provided to illustrate the methods. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

The Development of Web-based Graphical User Interface for Unified Modeling Data with Multi (Correlated) Responses

NASA Astrophysics Data System (ADS)

Made Tirta, I.; Anggraeni, Dian

2018-04-01

Statistical models have been developed rapidly into various directions to accommodate various types of data. Data collected from longitudinal, repeated measured, clustered data (either continuous, binary, count, or ordinal), are more likely to be correlated. Therefore statistical model for independent responses, such as Generalized Linear Model (GLM), Generalized Additive Model (GAM) are not appropriate. There are several models available to apply for correlated responses including GEEs (Generalized Estimating Equations), for marginal model and various mixed effect model such as GLMM (Generalized Linear Mixed Models) and HGLM (Hierarchical Generalized Linear Models) for subject spesific models. These models are available on free open source software R, but they can only be accessed through command line interface (using scrit). On the othe hand, most practical researchers very much rely on menu based or Graphical User Interface (GUI). We develop, using Shiny framework, standard pull down menu Web-GUI that unifies most models for correlated responses. The Web-GUI has accomodated almost all needed features. It enables users to do and compare various modeling for repeated measure data (GEE, GLMM, HGLM, GEE for nominal responses) much more easily trough online menus. This paper discusses the features of the Web-GUI and illustrates the use of them. In General we find that GEE, GLMM, HGLM gave very closed results.

Dorsolateral prefrontal cortex N-acetylaspartate/total creatine (NAA/tCr) loss in male recreational cannabis users.

PubMed

Hermann, Derik; Sartorius, Alexander; Welzel, Helga; Walter, Sigrid; Skopp, Gisela; Ende, Gabriele; Mann, Karl

2007-06-01

Cannabinoids present neurotoxic and neuroprotective properties in in vitro studies, inconsistent alterations in human neuroimaging studies, neuropsychological deficits, and an increased risk for psychotic episodes. Proton magnetic resonance spectroscopy ((1)H-MRS), neuropsychological testing, and hair analysis for cannabinoids was performed in 13 male nontreatment-seeking recreational cannabis users and 13 male control subjects. A significantly diminished N-acetylaspartate/total creatine (NAA/tCr) ratio in the dorsolateral prefrontal cortex (DLPFC) was observed in cannabis users (p = .0003). The NAA/tCr in the putamen/globus pallidum region correlated significantly with cannabidiol (R(2) = .66, p = .004). Results of the Wisconsin Card Sorting test, Trail making Test, and D2 test for attention were influenced by cannabinoids. Chronic recreational cannabis use is associated with an indication of diminished neuronal and axonal integrity in the DLPFC in this study. As chronic cannabis use is a risk factor for psychosis, these results are interesting because diminished NAA/tCr ratios in the DLPFC and neuropsychological deficits were also reported in schizophrenia. The strong positive correlation of NAA/tCr and cannabidiol in the putamen/globus pallidum is in line with neuroprotective properties of cannabidiol, which were also observed in in vitro model studies of Parkinson's disease.

LHCb trigger streams optimization

NASA Astrophysics Data System (ADS)

Derkach, D.; Kazeev, N.; Neychev, R.; Panin, A.; Trofimov, I.; Ustyuzhanin, A.; Vesterinen, M.

2017-10-01

The LHCb experiment stores around 1011 collision events per year. A typical physics analysis deals with a final sample of up to 107 events. Event preselection algorithms (lines) are used for data reduction. Since the data are stored in a format that requires sequential access, the lines are grouped into several output file streams, in order to increase the efficiency of user analysis jobs that read these data. The scheme efficiency heavily depends on the stream composition. By putting similar lines together and balancing the stream sizes it is possible to reduce the overhead. We present a method for finding an optimal stream composition. The method is applied to a part of the LHCb data (Turbo stream) on the stage where it is prepared for user physics analysis. This results in an expected improvement of 15% in the speed of user analysis jobs, and will be applied on data to be recorded in 2017.

IOOS Data Portals and Uniform On-line Browse Capabilities

NASA Astrophysics Data System (ADS)

Howard, M.; Currier, R. D.; Kobara, S.; Gayanilo, F.

2015-12-01

The Gulf of Mexico Coastal Ocean Observing System Regional Association (GCOOS-RA) is one of eleven Regional Associations organized under the NOAA-led U.S. Integrated Ocean Observing System (IOOS) Program Office. Each of the RAs operate standards-based regional data portals designed to aggregate near real-time and historical observed data and modeled outputs from distributed providers and to offer these and derived products in standardized ways to a diverse set of users. The RA's portals are based on the IOOS Data and Communications Plan which describes the functional elements needed for an interoperable system. One of these elements is called "Uniform On-line Browse" which is an informational service designed primarily to visualize the inventory of a portal. An on-line browse service supports the end user's need to discover what parameters are available, to learn the spatial and temporal extend of the holdings, and to examine the character of the data (e.g, variability, gappiness, etc). These pieces of information help the end user decide if the data are fit for his/her purpose and to construct valid data requests. Note that on-line browse is a distinctly different activity than data analysis because it seeks to yield knowledge about the inventory and not about what the data mean. "Uniform" on-line browse is a service that takes advantage of the standardization of the data portal's data access points. Most portals represent station locations on a map. This is a view of the data inventory but these plots are rarely generated by pulling data through the standards-based services offered to the end users but through methods only available to the portal programmers. This work will present results of Uniform On-line browse tools developed within GCOOS-RA and their applicability to other RA portals.

Dependence and resistance in community mental health care-Negotiations of user participation between staff and users.

PubMed

Femdal, I; Knutsen, I R

2017-10-01

WHAT IS KNOWN ON THE SUBJECT?: Implementation of user participation is described as a change from a paternalistic healthcare system to ideals of democratization where users' voices are heard in relational interplays with health professionals. The ideological shift involves a transition from welfare dependency and professional control towards more active service-user roles with associated rights and responsibilities. A collaborative relationship between users and professionals in mental health services is seen as important by both parties. Nevertheless, the health professionals find it challenging in practice to reorient their roles and to find productive ways to cooperate. WHAT THIS PAPER ADDS TO EXISTING KNOWLEDGE?: This study illuminates how user participation is negotiated and involves multiple and shifting subject positions in the collaboration between users and professionals in community mental health care. By taking different positions, the relationship between users and professionals develops through dynamic interaction. This study challenges understandings of equality and implicit "truths" in user participation by illuminating subtle forms of power and dilemmas that arise in user-professional negotiations. WHAT ARE THE IMPLICATIONS FOR PRACTICE?: Instead of denying the appearance of power, it is important to question the execution of power in the interplay between users and professionals. Focusing on the negotiation processes between users and professionals is important for increasing reflection on and improving understanding of the dynamic in collaboration and speech. By focusing on negotiations, power can be used in productive ways in user-professional relationships. Introduction Implementation of user participation is considered important in today's mental health care. Research shows, however, that user participation lacks clarity and provokes uncertainty regarding shifting roles. Aim To investigate negotiation of user participation in a microstudy of interplay between users and health professionals in community mental health care. Method This qualitative study is based on semi-structured in-depth interviews, involving ten service users and ten professionals in community mental health care in Norway. The analysis is inspired by Willig's model for Foucauldian discourse analysis. Results The study illuminates the dynamic nature of user participation that arises through negotiation between users' and professionals' positions as change enablers, dependents, resisters, persuaders and knowledge holders. Discussion Discourses of user participation allow for different subject positions in mental health care. User participation also involves government and questions of power, as well as ambitions of change and control. Professionals act in different ways to make and keep users active, participating, enterprising and self-governing, and users respond and take part within the same discursive framework. Implications for practice Awareness of subjects' positions in discourses is important to increase reflection on the dynamic interplay in user-professional collaboration. © 2017 John Wiley & Sons Ltd.

CTF Preprocessor User's Manual

DOE Office of Scientific and Technical Information (OSTI.GOV)

Avramova, Maria; Salko, Robert K.

2016-05-26

This document describes how a user should go about using the CTF pre- processor tool to create an input deck for modeling rod-bundle geometry in CTF. The tool was designed to generate input decks in a quick and less error-prone manner for CTF. The pre-processor is a completely independent utility, written in Fortran, that takes a reduced amount of input from the user. The information that the user must supply is basic information on bundle geometry, such as rod pitch, clad thickness, and axial location of spacer grids--the pre-processor takes this basic information and determines channel placement and connection informationmore » to be written to the input deck, which is the most time-consuming and error-prone segment of creating a deck. Creation of the model is also more intuitive, as the user can specify assembly and water-tube placement using visual maps instead of having to place them by determining channel/channel and rod/channel connections. As an example of the benefit of the pre-processor, a quarter-core model that contains 500,000 scalar-mesh cells was read into CTF from an input deck containing 200,000 lines of data. This 200,000 line input deck was produced automatically from a set of pre-processor decks that contained only 300 lines of data.« less

Active opioid use does not attenuate the humoral responses to inactivated influenza vaccine

PubMed Central

Moroz, Ekaterina; Albrecht, Randy A.; Aden, Brandon; Beeder, Ann Bordwine; Yuan, Jianda; García-Sastre, Adolfo; Edlin, Brian R.; Salvatore, Mirella

2016-01-01

Background Influenza vaccination is recommended for vulnerable individuals, including active drug users, to prevent influenza complications and decrease influenza spread. Recent studies suggest that opioids negatively regulate immune responses in experimental models, but the extent to which opioid use will affect the humoral responses to influenza vaccine in humans is unknown. This information is critical in maximizing vaccination efforts. Objective To determine whether there is a difference in antibody response after influenza vaccination in heroin or methadone users compared to control subjects. Methods We studied active heroin users, subjects on methadone maintenance treatment (MMT) and subjects that did not use any drugs before and 1 and 4 weeks after vaccination with trivalent influenza vaccine (TIV). We measured hemagglutination inhibition and microneutralization titers, and we compared geometric mean titers (GMT), and rates of seroprotection and seroconversion for each of the vaccine strains among the 3 groups of subjects. Results Heroin users, subjects on MMT and non-user controls mount a similarly robust serologic response to TIV. GMT and rates of seroprotection and seroconversion were not significantly different among groups. Conclusion Our results suggest that opioid use do not significantly alter antibody responses to influenza vaccine supporting the vaccination effort in these populations. PMID:26859239

Concept of Operations for the ESC Product Line Approach.

DTIC Science & Technology

1996-08-30

production of the application. Product Line Engineering Center ( PLEC ) defines and evolves product line architectures with the SAG. The PLEC is also tasked... PLEC , SAG, and PLAS and offers scenarios for asset and system development. • Section 4 outlines the ESC Product Line transition strategy. • Section...Line or System Needs User Select PLEC ; Assess PL architecture Product Line Architecture Development ments; architecture selection Architecture

A dynamic seating intervention for wheelchair seating discomfort.

PubMed

Crane, Barbara A; Holm, Margo B; Hobson, Douglas; Cooper, Rory A; Reed, Matthew P

2007-12-01

The objective of this study was to examine the effectiveness of a new user-adjustable wheelchair seating system designed to relieve discomfort for long-duration wheelchair users. This objective was carried out using the newly developed Tool for Assessing Wheelchair disComfort (TAWC) as the primary outcome measure. Two wheelchair users each tested two different designs and feedback from the wheelchair users regarding the first design was used to guide development of the second design. A single-subject research methodology was used, allowing long-duration (up to 2 wks per test) evaluation of the wheelchair seating systems and comparison of subject discomfort levels with those experienced during a baseline period using their own wheelchairs. The experimental wheelchair seating systems employed existing automotive seating with embedded pneumatic bladders that allowed adjustment of the seat and back-support characteristics. The test wheelchair also had tilt, recline, and elevating leg rests. The two subjects completed limited periods of testing with the first design, both finding poor results with either stable or increased levels of discomfort. Subject feedback was used to redesign the wheelchair seat. After redesign, both subjects tested the second design and found it substantially more comfortable. The selected research methodology was a very positive method for a progressive wheelchair seating design and the second design provided improved comfort for both users when compared with that experienced using their own wheelchairs and the first test wheelchair. Future research of this type of user-controlled technology is recommended.

Commodes: inconvenient conveniences.

PubMed Central

Naylor, J R; Mulley, G P

1993-01-01

OBJECTIVES--To investigate use of commodes and attitudes of users and carers to them. DESIGN--Interview with semi-structured questionnaire of subjects supplied with commodes from Leeds community appliance centre. SUBJECTS--140 users of a commode and 105 of their carers. RESULTS--Main reasons for being supplied with a commode were impaired mobility (130 subjects), difficulty in climbing stairs (128), and urinary incontinence (127). Main concerns of users and carers were lack of privacy (120 subjects felt embarrassed about using their commode, and 96 would not use it if someone was present); unpleasant smells (especially for 20 subjects who were confined to one room); physical appearance of commode chair (101 users said it had an unfavourable appearance, and 44 had tried to disguise it); and lack of follow up after commode was supplied (only 15 users and carers knew who to contact if there were problems). Users generally either had very positive or very negative attitudes to their commodes but most carers viewed them very negatively, especially with regard to cleaning them. CONCLUSIONS--Health professionals should be aware of people's need for privacy when advising them where to keep their commode. A standard commode is inappropriate for people confined to one room, and alternatives such as a chemical toilet should be considered. Regular follow up is needed to identify any problems such as uncomfortable or unsafe chairs. More thought should be given to the appearance of commodes in their design. Images FIG 1 FIG 2 PMID:8281060

A Refreshable, On-line Cache for HST Data Retrieval

NASA Astrophysics Data System (ADS)

Fraquelli, Dorothy A.; Ellis, Tracy A.; Ridgaway, Michael; DPAS Team

2016-01-01

We discuss upgrades to the HST Data Processing System, with an emphasis on the changes Hubble Space Telescope (HST) Archive users will experience. In particular, data are now held on-line (in a cache) removing the need to reprocess the data every time they are requested from the Archive. OTFR (on the fly reprocessing) has been replaced by a reprocessing system, which runs in the background. Data in the cache are automatically placed in the reprocessing queue when updated calibration reference files are received or when an improved calibration algorithm is installed. Data in the on-line cache are expected to be the most up to date version. These changes were phased in throughout 2015 for all active instruments.The on-line cache was populated instrument by instrument over the course of 2015. As data were placed in the cache, the flag that triggers OTFR was reset so that OTFR no longer runs on these data. "Hybrid" requests to the Archive are handled transparently, with data not yet in the cache provided via OTFR and the remaining data provided from the cache. Users do not need to make separate requests.Users of the MAST Portal will be able to download data from the cache immediately. For data not in the cache, the Portal will send the user to the standard "Retrieval Options Page," allowing the user to direct the Archive to process and deliver the data.The classic MAST Search and Retrieval interface has the same look and feel as previously. Minor changes, unrelated to the cache, have been made to the format of the Retrieval Options Page.

ascii2gdocs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nightingale, Trever

2011-11-30

Enables UNIX and Mac OS X command line users to put (individually or batch mode) local ascii files into Google Documents, where the ascii is converted to Google Document format using formatting the user can specify.

Predicting Facebook users' online privacy protection: risk, trust, norm focus theory, and the theory of planned behavior.

PubMed

Saeri, Alexander K; Ogilvie, Claudette; La Macchia, Stephen T; Smith, Joanne R; Louis, Winnifred R

2014-01-01

The present research adopts an extended theory of the planned behavior model that included descriptive norms, risk, and trust to investigate online privacy protection in Facebook users. Facebook users (N = 119) completed a questionnaire assessing their attitude, subjective injunctive norm, subjective descriptive norm, perceived behavioral control, implicit perceived risk, trust of other Facebook users, and intentions toward protecting their privacy online. Behavior was measured indirectly 2 weeks after the study. The data show partial support for the theory of planned behavior and strong support for the independence of subjective injunctive and descriptive norms. Risk also uniquely predicted intentions over and above the theory of planned behavior, but there were no unique effects of trust on intentions, nor of risk or trust on behavior. Implications are discussed.

Women and anabolic steroids: an analysis of a dozen users.

PubMed

Ip, Eric J; Barnett, Mitchell J; Tenerowicz, Michael J; Kim, Jennifer A; Wei, Hong; Perry, Paul J

2010-11-01

To provide an in-depth analysis of 12 female self-reported anabolic-androgenic steroid (AAS) users. Web-based survey. A Web-based survey was posted on 38 discussion boards of various fitness, bodybuilding, weightlifting, and steroid Web sites between February and June 2009. Participants completed a survey regarding demographics and use of AAS and other performance-enhancing agents (PEAs). A cohort of 1519 strength-trained subjects fully completed and submitted a valid survey. Five hundred eighteen subjects were self-reported AAS users consisting of 12 women and 506 men. One thousand one subjects were non-AAS users consisting of 230 women and 771 men. Demographic data and use of AAS and other PEAs. The female AAS users reported using an average of 8.8 PEAs in their routine. Compared with male AAS users and female non-AAS users, respectively, female AAS users were more likely to have met criteria for substance-dependence disorder (58.3% vs 23.4%; P = 0.01; 58.3% vs 9.1%; P < 0.001), have been diagnosed with a psychiatric illness (50.0% vs 17.4%; P = 0.01; 50.0% vs 22.2%; P = 0.04), and have reported a history of sexual abuse (41.7% vs 6.1%; P < 0.001; 41.7% vs 15.3%; P = 0.03). Female AAS users practice polypharmacy. Female AAS users are more likely to have qualified for substance-dependence disorder, have been diagnosed with a psychiatric illness, and have a history of sexual abuse than both male AAS users and female non-AAS users.

Discrimination of intonation contours by adolescents with cochlear implants.

PubMed

Holt, Colleen M; McDermott, Hugh J

2013-12-01

Differences in fundamental frequency (F0) contour peak alignment contribute to the perception of pitch accents in speech intonation. The present study assessed the discrimination of differences in F0 contour peak alignment by adolescent users of cochlear implants (CIs). In Experiment 1, subjects discriminated between rise-fall F0 contours located early in the syllable and those aligned late. Recorded utterances with manipulated F0 were used as stimuli and all subjects wore a unilateral CI. In Experiment 2, bilaterally-implanted subjects repeated Experiment 1 in the bilateral condition. Twenty-one CI users aged 12-21 years participated. A normally-hearing control group (n = 20) also completed Experiment 1. Listeners with normal hearing (NH) could discriminate between F0 peaks differing by 80 ms or more. Results varied among the CI users, with only four users displaying a pattern of results similar to that of the NH listeners. Sixteen CI users responded inconsistently or at chance levels (p > 0.05; binomial test). Ten CI users who were bilaterally implanted completed the tests in unilateral and bilateral listening conditions. Results suggest that CI users may have difficulty discriminating between F0 alignment and that use of bilateral implants did not provide an advantage to discrimination.

Spectro-temporal cues enhance modulation sensitivity in cochlear implant users.

PubMed

Zheng, Yi; Escabí, Monty; Litovsky, Ruth Y

2017-08-01

Although speech understanding is highly variable amongst cochlear implants (CIs) subjects, the remarkably high speech recognition performance of many CI users is unexpected and not well understood. Numerous factors, including neural health and degradation of the spectral information in the speech signal of CIs, likely contribute to speech understanding. We studied the ability to use spectro-temporal modulations, which may be critical for speech understanding and discrimination, and hypothesize that CI users adopt a different perceptual strategy than normal-hearing (NH) individuals, whereby they rely more heavily on joint spectro-temporal cues to enhance detection of auditory cues. Modulation detection sensitivity was studied in CI users and NH subjects using broadband "ripple" stimuli that were modulated spectrally, temporally, or jointly, i.e., spectro-temporally. The spectro-temporal modulation transfer functions of CI users and NH subjects was decomposed into spectral and temporal dimensions and compared to those subjects' spectral-only and temporal-only modulation transfer functions. In CI users, the joint spectro-temporal sensitivity was better than that predicted by spectral-only and temporal-only sensitivity, indicating a heightened spectro-temporal sensitivity. Such an enhancement through the combined integration of spectral and temporal cues was not observed in NH subjects. The unique use of spectro-temporal cues by CI patients can yield benefits for use of cues that are important for speech understanding. This finding has implications for developing sound processing strategies that may rely on joint spectro-temporal modulations to improve speech comprehension of CI users, and the findings of this study may be valuable for developing clinical assessment tools to optimize CI processor performance. Copyright © 2017 Elsevier B.V. All rights reserved.

A computer program for converting rectangular coordinates to latitude-longitude coordinates

USGS Publications Warehouse

Rutledge, A.T.

1989-01-01

A computer program was developed for converting the coordinates of any rectangular grid on a map to coordinates on a grid that is parallel to lines of equal latitude and longitude. Using this program in conjunction with groundwater flow models, the user can extract data and results from models with varying grid orientations and place these data into grid structure that is oriented parallel to lines of equal latitude and longitude. All cells in the rectangular grid must have equal dimensions, and all cells in the latitude-longitude grid measure one minute by one minute. This program is applicable if the map used shows lines of equal latitude as arcs and lines of equal longitude as straight lines and assumes that the Earth 's surface can be approximated as a sphere. The program user enters the row number , column number, and latitude and longitude of the midpoint of the cell for three test cells on the rectangular grid. The latitude and longitude of boundaries of the rectangular grid also are entered. By solving sets of simultaneous linear equations, the program calculates coefficients that are used for making the conversion. As an option in the program, the user may build a groundwater model file based on a grid that is parallel to lines of equal latitude and longitude. The program reads a data file based on the rectangular coordinates and automatically forms the new data file. (USGS)

TLINES: A Computer Program for Circuits of Transmission Lines.

DTIC Science & Technology

1983-12-01

of various lengths are handled by stringing together many short lines, with the assumption that each of the longer lines has a length approximated as...expressed in terms of transmission lines numbered from 2 through CAPM , connected in numerical sequence as in figure 3. Line 1 is a dummy element disconnected...from line 2 and the rest of the circuit. Lines 2 through CAPM can each be set to any impedance the user desires. Line CAPM +1 is a zero-impedance line

MIRADS-2 user's manual

NASA Technical Reports Server (NTRS)

1975-01-01

An on-line data storage and retrieval system which allows the user to extract and process information from stored data bases is described. The capabilities of the system are provided by a general purpose computer program containing several functional modules. The modules contained in MIRADS are briefly described along with user terminal operation procedures and MIRADS commands.

User's Guide for SKETCH

NASA Technical Reports Server (NTRS)

Hedgley, David R., Jr.

2000-01-01

A user's guide for the computer program SKETCH is presented on this disk. SKETCH solves a popular problem in computer graphics-the removal of hidden lines from images of solid objects. Examples and illustrations are included in the guide. Also included is the SKETCH program, so a user can incorporate the information into a particular software system.

Low-Fatigue Hand Controller For Remote Manipulator

NASA Technical Reports Server (NTRS)

Maclaren, Brice; Mcmurray, Gary; Lipkin, Harvey

1993-01-01

Universal master controller used in brace mode, in which user's forearm rests atop upper (forearm) module. Alternatively, user manipulates hand controller in side mode, which gives greater latitude for motion but requires more muscular effort. Controller provides six degrees of freedom and reflects, back to user, scaled versions of forces experienced by manipulator. Manipulator designed to condense work space into user's natural work volume. Operated by both right-handed and left-handed users. Does not interfere with user's natural movements or obstruct line of sight. Controller compact and portable.

BioCatalogue: a universal catalogue of web services for the life sciences

PubMed Central

Bhagat, Jiten; Tanoh, Franck; Nzuobontane, Eric; Laurent, Thomas; Orlowski, Jerzy; Roos, Marco; Wolstencroft, Katy; Aleksejevs, Sergejs; Stevens, Robert; Pettifer, Steve; Lopez, Rodrigo; Goble, Carole A.

2010-01-01

The use of Web Services to enable programmatic access to on-line bioinformatics is becoming increasingly important in the Life Sciences. However, their number, distribution and the variable quality of their documentation can make their discovery and subsequent use difficult. A Web Services registry with information on available services will help to bring together service providers and their users. The BioCatalogue (http://www.biocatalogue.org/) provides a common interface for registering, browsing and annotating Web Services to the Life Science community. Services in the BioCatalogue can be described and searched in multiple ways based upon their technical types, bioinformatics categories, user tags, service providers or data inputs and outputs. They are also subject to constant monitoring, allowing the identification of service problems and changes and the filtering-out of unavailable or unreliable resources. The system is accessible via a human-readable ‘Web 2.0’-style interface and a programmatic Web Service interface. The BioCatalogue follows a community approach in which all services can be registered, browsed and incrementally documented with annotations by any member of the scientific community. PMID:20484378

BioCatalogue: a universal catalogue of web services for the life sciences.

PubMed

Bhagat, Jiten; Tanoh, Franck; Nzuobontane, Eric; Laurent, Thomas; Orlowski, Jerzy; Roos, Marco; Wolstencroft, Katy; Aleksejevs, Sergejs; Stevens, Robert; Pettifer, Steve; Lopez, Rodrigo; Goble, Carole A

2010-07-01

The use of Web Services to enable programmatic access to on-line bioinformatics is becoming increasingly important in the Life Sciences. However, their number, distribution and the variable quality of their documentation can make their discovery and subsequent use difficult. A Web Services registry with information on available services will help to bring together service providers and their users. The BioCatalogue (http://www.biocatalogue.org/) provides a common interface for registering, browsing and annotating Web Services to the Life Science community. Services in the BioCatalogue can be described and searched in multiple ways based upon their technical types, bioinformatics categories, user tags, service providers or data inputs and outputs. They are also subject to constant monitoring, allowing the identification of service problems and changes and the filtering-out of unavailable or unreliable resources. The system is accessible via a human-readable 'Web 2.0'-style interface and a programmatic Web Service interface. The BioCatalogue follows a community approach in which all services can be registered, browsed and incrementally documented with annotations by any member of the scientific community.

Off-line compatible electronic cash method and system

DOEpatents

Kravitz, D.W.; Gemmell, P.S.; Brickell, E.F.

1998-11-03

An off-line electronic cash system having an electronic coin, a bank B, a payee S, and a user U with an account at the bank B as well as a user password z{sub u,i}, has a method for performing an electronic cash transfer. An electronic coin is withdrawn from the bank B by the user U and an electronic record of the electronic coin is stored by the bank B. The coin is paid to the payee S by the user U. The payee S deposits the coin with the bank B. A determination is made that the coin is spent and the record of the coin is deleted by the bank B. A further deposit of the same coin after the record is deleted is determined. Additionally, a determination is made which user U originally withdrew the coin after deleting the record. To perform these operations a key pair is generated by the user, including public and secret signature keys. The public signature key along with a user password z{sub u,i} and a withdrawal amount are sent to the bank B by the user U. In response, the bank B sends a coin to the user U signed by the secret key of the bank indicating the value of the coin and the public key of the user U. The payee S transmits a challenge counter to the user U prior to receiving the coin. 16 figs.

Off-line compatible electronic cash method and system

DOEpatents

Kravitz, David W.; Gemmell, Peter S.; Brickell, Ernest F.

1998-01-01

An off-line electronic cash system having an electronic coin, a bank B, a payee S, and a user U with an account at the bank B as well as a user password z.sub.u,i, has a method for performing an electronic cash transfer. An electronic coin is withdrawn from the bank B by the user U and an electronic record of the electronic coin is stored by the bank B. The coin is paid to the payee S by the user U. The payee S deposits the coin with the bank B. A determination is made that the coin is spent and the record of the coin is deleted by the bank B. A further deposit of the same coin after the record is deleted is determined. Additionally, a determination is made which user U originally withdrew the coin after deleting the record. To perform these operations a key pair is generated by the user, including public and secret signature keys. The public signature key along with a user password z.sub.u,i and a withdrawal amount are sent to the bank B by the user U. In response, the bank B sends a coin to the user U signed by the secret key of the bankindicating the value of the coin and the public key of the user U. The payee S transmits a challenge counter to the user U prior to receiving the coin.

Parsley: a Command-Line Parser for Astronomical Applications

NASA Astrophysics Data System (ADS)

Deich, William

Parsley is a sophisticated keyword + value parser, packaged as a library of routines that offers an easy method for providing command-line arguments to programs. It makes it easy for the user to enter values, and it makes it easy for the programmer to collect and validate the user's entries. Parsley is tuned for astronomical applications: for example, dates entered in Julian, Modified Julian, calendar, or several other formats are all recognized without special effort by the user or by the programmer; angles can be entered using decimal degrees or dd:mm:ss; time-like intervals as decimal hours, hh:mm:ss, or a variety of other units. Vectors of data are accepted as readily as scalars.

Symptomatic accommodative and binocular dysfunctions from the use of flat-panel displays

PubMed Central

Porcar, Esteban; Montalt, Juan Carlos; Pons, Álvaro M.; España-Gregori, Enrique

2018-01-01

AIM To determine the presence of symptomatic accommodative and non-strabismic binocular dysfunctions (ANSBD) in a non-presbyopic population of video display unit (VDU) users with flat-panel displays. METHODS One hundred and one VDU users, aged between 20 to 34y, initially participated in the study. This study excluded contact-lens wearers and subjects who had undergone refractive surgery or had any systemic or ocular disease. First, subjects were asked about the type and nature of eye symptoms they experienced during VDU use. Then, a thorough eye examination excluded those subjects with a significant uncorrected refractive error or other problem, such as ocular motility disorders, vertical deviation, strabismus and eye diseases. Finally, the remaining participants underwent an exhaustive assessment of their accommodative and binocular vision status. RESULTS Eighty-nine VDU users (46 females and 43 males) were included in this study. They used flat-panel displays for an average of 5±1.9h a day. Twenty subjects presented ANSBD (22.5%). Convergence excess was the most frequent non-strabismic binocular dysfunction (9 subjects), followed by fusional vergence dysfunction (3 subjects) and convergence insufficiency (2 subjects). Within the accommodative dysfunctions, accommodative excess was the most common (4 subjects), followed by accommodative insufficiency (2 subjects). Moderate to severe eye symptoms were found in 13 subjects with ANSBD. CONCLUSION Significant eye symptoms in VDU users with accommodative and/or non-strabismic binocular dysfunctions often occur and should not be underestimated; therefore, an appropriate evaluation of accommodative and binocular vision status is more important for this population. PMID:29600186

Integrating Subject Pathfinders into Online Catalogs.

ERIC Educational Resources Information Center

Jarvis, William E.

1985-01-01

Discusses the integration of subject pathfinders into online public access catalogs (OPAC) through following features: within the OPAC, offline user guide manuals, remotely printed upon user request, or online as saved searches displayed in help screen format. Excerpts of a pathfinder display for biotechnology are presented. Four sources are…

User intent prediction with a scaled conjugate gradient trained artificial neural network for lower limb amputees using a powered prosthesis.

PubMed

Woodward, Richard B; Spanias, John A; Hargrove, Levi J

2016-08-01

Powered lower limb prostheses have the ability to provide greater mobility for amputee patients. Such prostheses often have pre-programmed modes which can allow activities such as climbing stairs and descending ramps, something which many amputees struggle with when using non-powered limbs. Previous literature has shown how pattern classification can allow seamless transitions between modes with a high accuracy and without any user interaction. Although accurate, training and testing each subject with their own dependent data is time consuming. By using subject independent datasets, whereby a unique subject is tested against a pooled dataset of other subjects, we believe subject training time can be reduced while still achieving an accurate classification. We present here an intent recognition system using an artificial neural network (ANN) with a scaled conjugate gradient learning algorithm to classify gait intention with user-dependent and independent datasets for six unilateral lower limb amputees. We compare these results against a linear discriminant analysis (LDA) classifier. The ANN was found to have significantly lower classification error (P<;0.05) than LDA with all user-dependent step-types, as well as transitional steps for user-independent datasets. Both types of classifiers are capable of making fast decisions; 1.29 and 2.83 ms for the LDA and ANN respectively. These results suggest that ANNs can provide suitable and accurate offline classification in prosthesis gait prediction.

Everyday listening questionnaire: correlation between subjective hearing and objective performance.

PubMed

Brendel, Martina; Frohne-Buechner, Carolin; Lesinski-Schiedat, Anke; Lenarz, Thomas; Buechner, Andreas

2014-01-01

Clinical experience has demonstrated that speech understanding by cochlear implant (CI) recipients has improved over recent years with the development of new technology. The Everyday Listening Questionnaire 2 (ELQ 2) was designed to collect information regarding the challenges faced by CI recipients in everyday listening. The aim of this study was to compare self-assessment of CI users using ELQ 2 with objective speech recognition measures and to compare results between users of older and newer coding strategies. During their regular clinical review appointments a group of representative adult CI recipients implanted with the Advanced Bionics implant system were asked to complete the questionnaire. The first 100 patients who agreed to participate in this survey were recruited independent of processor generation and speech coding strategy. Correlations between subjectively scored hearing performance in everyday listening situations and objectively measured speech perception abilities were examined relative to the speech coding strategies used. When subjects were grouped by strategy there were significant differences between users of older 'standard' strategies and users of the newer, currently available strategies (HiRes and HiRes 120), especially in the categories of telephone use and music perception. Significant correlations were found between certain subjective ratings and the objective speech perception data in noise. There is a good correlation between subjective and objective data. Users of more recent speech coding strategies tend to have fewer problems in difficult hearing situations.

Differences in the Limits of Stability Between Older Rolling Walker Users and Older Single-Tip-Cane Users - A Preliminary Study.

PubMed

Liu, Hao Howe; Quiben, Myles; Holmes, Clayton; Connors, Michael; Salem, Yasser

To identify the differences in the limits of stability (LOS) between older rolling walker and single-tip-cane users. This was a matched paired t-test design with repeated measure. Eighteen older subjects were matched based on age, gender, and functional level. The subjects were assessed using the multidirectional reach test initially and 5-month later in four directions: forward, backward, leftward, and rightward. Initially, there were no differences between cane users and rolling walker users in the LOS in all directions. However, 5-month later, the cane users who held their canes in their right hand had significantly better stability in forward and rightward reach than the walker users (p < .05). Further, the walker users demonstrated significantly decreased functional reach in forward reach (p < .05). Cane users might have better stability than walker users in the forward direction and in the direction toward the side holding the cane. This study may provide guide for clinicians including nurses for selecting appropriate rehabilitative interventions for older adults using walkers and canes.

Information Theoretic Evaluation of a Noiseband-Based Cochlear Implant Simulator

PubMed Central

Aguiar, Daniel E.; Taylor, N. Ellen; Li, Jing; Gazanfari, Daniel K.; Talavage, Thomas M.; Laflen, J. Brandon; Neuberger, Heidi; Svirsky, Mario A.

2015-01-01

Noise-band vocoders are often used to simulate the signal processing algorithms used in cochlear implants (CIs), producing acoustic stimuli that may be presented to normal hearing (NH) subjects. Such evaluations may obviate the heterogeneity of CI user populations, achieving greater experimental control than when testing on CI subjects. However, it remains an open question whether advancements in algorithms developed on NH subjects using a simulator will necessarily improve performance in CI users. This study assessed the similarity in vowel identification of CI subjects and NH subjects using an 8-channel noise-band vocoder simulator configured to match input and output frequencies or to mimic output after a basalward shift of input frequencies. Under each stimulus condition, NH subjects performed the task both with and without feedback/training. Similarity of NH subjects to CI users was evaluated using correct identification rates and information theoretic approaches. Feedback/training produced higher rates of correct identification, as expected, but also resulted in error patterns that were closer to those of the CI users. Further evaluation remains necessary to determine how patterns of confusion at the token level are affected by the various parameters in CI simulators, providing insight into how a true CI simulation may be developed to facilitate more rapid prototyping and testing of novel CI signal processing and electrical stimulation strategies. PMID:26409068

Commodes: inconvenient conveniences.

PubMed

Naylor, J R; Mulley, G P

1993-11-13

To investigate use of commodes and attitudes of users and carers to them. Interview with semi-structured questionnaire of subjects supplied with commodes from Leeds community appliance centre. 140 users of a commode and 105 of their carers. Main reasons for being supplied with a commode were impaired mobility (130 subjects), difficulty in climbing stairs (128), and urinary incontinence (127). Main concerns of users and carers were lack of privacy (120 subjects felt embarrassed about using their commode, and 96 would not use it if someone was present); unpleasant smells (especially for 20 subjects who were confined to one room); physical appearance of commode chair (101 users said it had an unfavourable appearance, and 44 had tried to disguise it); and lack of follow up after commode was supplied (only 15 users and carers knew who to contact if there were problems). Users generally either had very positive or very negative attitudes to their commodes but most carers viewed them very negatively, especially with regard to cleaning them. Health professionals should be aware of people's need for privacy when advising them where to keep their commode. A standard commode is inappropriate for people confined to one room, and alternatives such as a chemical toilet should be considered. Regular follow up is needed to identify any problems such as uncomfortable or unsafe chairs. More thought should be given to the appearance of commodes in their design.

Specdata: Automated Analysis Software for Broadband Spectra

NASA Astrophysics Data System (ADS)

Oliveira, Jasmine N.; Martin-Drumel, Marie-Aline; McCarthy, Michael C.

2017-06-01

With the advancement of chirped-pulse techniques, broadband rotational spectra with a few tens to several hundred GHz of spectral coverage are now routinely recorded. When studying multi-component mixtures that might result, for example, with the use of an electrical discharge, lines of new chemical species are often obscured by those of known compounds, and analysis can be laborious. To address this issue, we have developed SPECdata, an open source, interactive tool which is designed to simplify and greatly accelerate the spectral analysis and discovery. Our software tool combines both automated and manual components that free the user from computation, while giving him/her considerable flexibility to assign, manipulate, interpret and export their analysis. The automated - and key - component of the new software is a database query system that rapidly assigns transitions of known species in an experimental spectrum. For each experiment, the software identifies spectral features, and subsequently assigns them to known molecules within an in-house database (Pickett .cat files, list of frequencies...), or those catalogued in Splatalogue (using automatic on-line queries). With suggested assignments, the control is then handed over to the user who can choose to accept, decline or add additional species. Data visualization, statistical information, and interactive widgets assist the user in making decisions about their data. SPECdata has several other useful features intended to improve the user experience. Exporting a full report of the analysis, or a peak file in which assigned lines are removed are among several options. A user may also save their progress to continue at another time. Additional features of SPECdata help the user to maintain and expand their database for future use. A user-friendly interface allows one to search, upload, edit or update catalog or experiment entries.

XMGR5 users manual

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, K.R.; Fisher, J.E.

1997-03-01

ACE/gr is XY plotting tool for workstations or X-terminals using X. A few of its features are: User defined scaling, tick marks, labels, symbols, line styles, colors. Batch mode for unattended plotting. Read and write parameters used during a session. Polynomial regression, splines, running averages, DFT/FFT, cross/auto-correlation. Hardcopy support for PostScript, HP-GL, and FrameMaker.mif format. While ACE/gr has a convenient point-and-click interface, most parameter settings and operations are available through a command line interface (found in Files/Commands).

An exploratory investigation of the translation of Pacific Northwest Laboratory's print manuals system to an on-line manuals system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heubach, J.G.; Hunt, S.T.; Pond, L.R.

1992-06-01

Information management technology has proliferated in the past decade in response to the information explosion. As documentation accumulates, the need to access information residing in manuals, handbooks and regulations conveniently, accurately, and quickly has increased. However, studies show that only fractions of the available information is read (Martin, 1978). Consequently, one of the biggest challenges in linking information and electronic management of information is to use the power of communication technology to meet the information needs of the audience. Pacific Northwest Laboratories' (PNL) investigation of translating its print manual system to an on-line system fits this challenge precisely. PNL's manualsmore » contain a tremendous amount of information for which manual holders are responsible. To perform their tasks in compliance with policy and procedure guidelines, users need to access information accurately, conveniently, and quickly. In order to select and use information management tools wisely, answers must be sought to a few basic questions. Communication experts cite four key questions: What do users want What do users need What characteristics of an on-line information system affect its usefulness Who are the users whose wants and needs are to be met Once these questions are answered, attention can be focused on finding the best match between user requirements and technology characteristics and weighing the costs and benefits of proposed options.« less

An exploratory investigation of the translation of Pacific Northwest Laboratory`s print manuals system to an on-line manuals system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heubach, J.G.; Hunt, S.T.; Pond, L.R.

1992-06-01

Information management technology has proliferated in the past decade in response to the information explosion. As documentation accumulates, the need to access information residing in manuals, handbooks and regulations conveniently, accurately, and quickly has increased. However, studies show that only fractions of the available information is read (Martin, 1978). Consequently, one of the biggest challenges in linking information and electronic management of information is to use the power of communication technology to meet the information needs of the audience. Pacific Northwest Laboratories` (PNL) investigation of translating its print manual system to an on-line system fits this challenge precisely. PNL`s manualsmore » contain a tremendous amount of information for which manual holders are responsible. To perform their tasks in compliance with policy and procedure guidelines, users need to access information accurately, conveniently, and quickly. In order to select and use information management tools wisely, answers must be sought to a few basic questions. Communication experts cite four key questions: What do users want? What do users need? What characteristics of an on-line information system affect its usefulness? Who are the users whose wants and needs are to be met? Once these questions are answered, attention can be focused on finding the best match between user requirements and technology characteristics and weighing the costs and benefits of proposed options.« less

47 CFR 69.4 - Charges to be filed.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) ACCESS CHARGES... shall include charges for the End User Common Line element, and for line port costs in excess of basic... each of the following elements: (1) [Reserved] (2) Carrier common line, provided that after June 30...

Measuring the Subjective User eXperience

NASA Astrophysics Data System (ADS)

Kaptein, Maurits

Measuring the subjective user experience is a challenging task. In this tutorial we will demonstrate how psychological constructs can be divided in separate variables, each measured by its individual questionnaire items. The tutorial will address the analysis of the questionnaire data to estimate its validity and reliability. Analysis will be demonstrated using SPSS.

Controlling mechanisms over the internet

NASA Astrophysics Data System (ADS)

Lumia, Ronald

1997-01-01

The internet, widely available throughout the world, can be used to control robots, machine tools, and other mechanisms. This paper will describe a low-cost virtual collaborative environment (VCE) which will connect users with distant equipment. The system is based on PC technology, and incorporates off-line-programming with on-line execution. A remote user programs the systems graphically and simulates the motions and actions of the mechanism until satisfied with the functionality of the program. The program is then transferred from the remote site to the local site where the real equipment exists. At the local site, the simulation is run again to check the program from a safety standpoint. Then, the local user runs the program on the real equipment. During execution, a camera in the real workspace provides an image back to the remote user through a teleconferencing system. The system costs approximately 12,500 dollars and represents a low-cost alternative to the Sandia National Laboratories VCE.

HIV vaccine trials: will intravenous drug users enroll?

PubMed Central

Meyers, K; Metzger, D S; Navaline, H; Woody, G E; McLellan, A T

1994-01-01

OBJECTIVES. The purpose of this study was to assess the willingness of intravenous drug users to participate in a preventive human immunodeficiency virus (HIV) vaccine efficacy trial. METHODS. Of the 347 intravenous drug users in methadone treatment who were approached for participation, 257 completed a battery of self-administered questionnaires assessing risk behaviors, interest in vaccine trials, and other vaccine-related information. Data from 16 known seropositives and 1 inconsistent responder were dropped from analyses (n = 240). RESULTS. Fifty-two percent of the subjects expressed a willingness to be one of the first individuals to participate in a preventive HIV vaccine efficacy trial. Subjects who had recently shared needles or works and subjects who trusted the government to ensure vaccine safety were both twice as likely to report interest in participation. Twenty-two percent of subjects reported that they would increase needle sharing if vaccinated. Thirty percent did not know what a vaccine was. CONCLUSIONS. These findings suggest that some in-treatment intravenous drug users would volunteer for a preventive HIV vaccine efficacy trial. Education and counseling will be required to ensure that subjects fully understand the trial's purposes, methods, risks and benefits. PMID:8179045

Emotion scents: a method of representing user emotions on GUI widgets

NASA Astrophysics Data System (ADS)

Cernea, Daniel; Weber, Christopher; Ebert, Achim; Kerren, Andreas

2013-01-01

The world of desktop interfaces has been dominated for years by the concept of windows and standardized user interface (UI) components. Still, while supporting the interaction and information exchange between the users and the computer system, graphical user interface (GUI) widgets are rather one-sided, neglecting to capture the subjective facets of the user experience. In this paper, we propose a set of design guidelines for visualizing user emotions on standard GUI widgets (e.g., buttons, check boxes, etc.) in order to enrich the interface with a new dimension of subjective information by adding support for emotion awareness as well as post-task analysis and decision making. We highlight the use of an EEG headset for recording the various emotional states of the user while he/she is interacting with the widgets of the interface. We propose a visualization approach, called emotion scents, that allows users to view emotional reactions corresponding to di erent GUI widgets without in uencing the layout or changing the positioning of these widgets. Our approach does not focus on highlighting the emotional experience during the interaction with an entire system, but on representing the emotional perceptions and reactions generated by the interaction with a particular UI component. Our research is motivated by enabling emotional self-awareness and subjectivity analysis through the proposed emotionenhanced UI components for desktop interfaces. These assumptions are further supported by an evaluation of emotion scents.

Dynamics of backlight luminance for using smartphone in dark environment

NASA Astrophysics Data System (ADS)

Na, Nooree; Jang, Jiho; Suk, Hyeon-Jeong

2014-02-01

This study developed dynamic backlight luminance, which gradually changes as time passes for comfortable use of a smartphone display in a dark environment. The study was carried out in two stages. In the first stage, a user test was conducted to identify the optimal luminance by assessing the facial squint level, subjective glare evaluation, eye blink frequency and users' subjective preferences. Based on the results of the user test, the dynamics of backlight luminance was designed. It has two levels of luminance: the optimal level for initial viewing to avoid sudden glare or fatigue to users' eyes, and the optimal level for constant viewing, which is comfortable, but also bright enough for constant reading of the displayed material. The luminance for initial viewing starts from 10 cd/m2, and it gradually increases to 40 cd/m2 for users' visual comfort at constant viewing for 20 seconds; In the second stage, a validation test on dynamics of backlight luminance was conducted to verify the effectiveness of the developed dynamics. It involving users' subjective preferences, eye blink frequency, and brainwave analysis using the electroencephalogram (EEG) to confirm that the proposed dynamic backlighting enhances users' visual comfort and visual cognition, particularly for using smartphones in a dark environment.

The effect of Gestalt laws of perceptual organization on the comprehension of three-variable bar and line graphs.

PubMed

Ali, Nadia; Peebles, David

2013-02-01

We report three experiments investigating the ability of undergraduate college students to comprehend 2 x 2 "interaction" graphs from two-way factorial research designs. Factorial research designs are an invaluable research tool widely used in all branches of the natural and social sciences, and the teaching of such designs lies at the core of many college curricula. Such data can be represented in bar or line graph form. Previous studies have shown, however, that people interpret these two graphical forms differently. In Experiment 1, participants were required to interpret interaction data in either bar or line graphs while thinking aloud. Verbal protocol analysis revealed that line graph users were significantly more likely to misinterpret the data or fail to interpret the graph altogether. The patterns of errors line graph users made were interpreted as arising from the operation of Gestalt principles of perceptual organization, and this interpretation was used to develop two modified versions of the line graph, which were then tested in two further experiments. One of the modifications resulted in a significant improvement in performance. Results of the three experiments support the proposed explanation and demonstrate the effects (both positive and negative) of Gestalt principles of perceptual organization on graph comprehension. We propose that our new design provides a more balanced representation of the data than the standard line graph for nonexpert users to comprehend the full range of relationships in two-way factorial research designs and may therefore be considered a more appropriate representation for use in educational and other nonexpert contexts.

Ergonomic and anthropometric consideration for library furniture in an Iranian public university.

PubMed

Osquei-Zadeh, R; Ghamari, J; Abedi, M; Shiri, H

2012-01-01

In our competing educational world, students spend a considerable part of their daily life, studying at library furniture. Not surprisingly, due to lack of proper anthropometric databases, these products have typically been ill fitted for the intended user populations. To verify the optimum anthropometric match of library furniture within an academic environment, through a combined qualitative and quantitative approach. 267 (120 female and 147 male) students, were subjected to 11 standard anthropometric measurements. In line with the measurements, subjective evaluations were also considered through detailed fitting trials on selected groups of participants. Combinational equations defined the unacceptable furniture dimensions according to elbow and sitting popliteal heights, mainly for smaller and taller divisions of the studied population, which were systematically comparable along with subjective and objective outcomes. In brief, if we classified studied students into "small," "medium," and "tall" groups, the design dimensions should be altered by -5.1, -2.2, and +1.6 cm for chair seat height; and by -8.3, -5.4, and +1.1 cm for table height, for each student group, respectively. The furniture size to be used by Iranian students should be changed to fit their anthropometric measures.

A componential model of human interaction with graphs: 1. Linear regression modeling

NASA Technical Reports Server (NTRS)

Gillan, Douglas J.; Lewis, Robert

1994-01-01

Task analyses served as the basis for developing the Mixed Arithmetic-Perceptual (MA-P) model, which proposes (1) that people interacting with common graphs to answer common questions apply a set of component processes-searching for indicators, encoding the value of indicators, performing arithmetic operations on the values, making spatial comparisons among indicators, and repsonding; and (2) that the type of graph and user's task determine the combination and order of the components applied (i.e., the processing steps). Two experiments investigated the prediction that response time will be linearly related to the number of processing steps according to the MA-P model. Subjects used line graphs, scatter plots, and stacked bar graphs to answer comparison questions and questions requiring arithmetic calculations. A one-parameter version of the model (with equal weights for all components) and a two-parameter version (with different weights for arithmetic and nonarithmetic processes) accounted for 76%-85% of individual subjects' variance in response time and 61%-68% of the variance taken across all subjects. The discussion addresses possible modifications in the MA-P model, alternative models, and design implications from the MA-P model.

The importance of user centered design methods applied to the design of a new workstation: a case study.

PubMed

Duschenes, Ronaldo; Mendes, Andressa; Betiol, Adriana; Barreto, Suzana

2012-01-01

This paper presents a case study of the application of user centered design methodologies in the product development for a line of ergonomic office furniture. The study aimed to analyze the experience of using a workstation from the perspective of two groups of users, installers and end users. The observation of users in their natural context of use not only allowed the development team to identify key needs and strategies of the users, transforming them into design solutions, but mainly it warned them of the importance and impact of user involvement in the product development cycle.

Line-Drawing Enhanced Interactive Mural Restoration for Dunhuang Mogao Grottoes

NASA Astrophysics Data System (ADS)

Fu, X. Y.; Han, Y.; Sun, Z. J.; Ma, X. J.; Xu, Y. Q.

2017-08-01

Dunhuang Mogao Grottoes in western China is one of the most famous World Cultural Heritage Sites, known for its glorious Chinese Buddhist art spanning a period of 1,000 years. However, it has been suffering from damage and degradation caused by man-made and natural factors. In this article, we present a novel line-drawing enhanced interactive system for digital restoration of damaged murals in Mogao Grottoes. Our system consists of four components, namely data pre-processing, damaged area selection, line-drawing segmentation, and mural restoration. Each component is a hybrid of efficient algorithms and user interactions. We introduce the infrastructure and process of using our system, from data capture and collection, database establishment, to interactive restoration. We conduct a user study with 15 participants who have varied experiences with and skills on repairing murals and editing images. Results and feedback suggest that our system can achieve satisfactory restoration results without overburdening the users. It can benefit both experts trained in restoration and amateurs interested in cultural heritage conservation.

Electronic Commerce "in the dark"

NASA Astrophysics Data System (ADS)

Buzzi, Maria Claudia; Buzzi, Marina; Leporini, Barbara; Senette, Caterina

The widespread diffusion of electronic commerce offers a great opportunity for blind people. We describe the results of an electronic survey carried out with 22 blind and 22 sighted users in order to understand the difficulties and obstacles they experience shopping on-line, and solicit their expectations and suggestions for making the interaction simpler and more satisfying. Results show that blind users shop on-line much less than their sighted counterparts, since they encounter more difficulties not only when making a purchase, but even in the navigation phase preceding the commercial transaction. Complex layouts and unstructured content can prevent an e-transaction from being successfully completed. Furthermore, security, privacy and trustiness, common concerns for all consumers, also impact on the fear of buying via Internet for the visually impaired. Poor usability leads to a potential loss of revenue for on-line companies and a lost opportunity to increase a blind person's independence. Providing simpler, more understandable UIs would benefit all users and fuel the expansion of electronic commerce.

A User Study on Tactile Graphic Generation Methods

ERIC Educational Resources Information Center

Krufka, S. E.; Barner, K. E.

2006-01-01

Methods to automatically convert graphics into tactile representations have been recently investigated, creating either raised-line or relief images. In particular, we briefly review one raised-line method where important features are emphasized. This paper focuses primarily on the effects of such emphasis and on comparing both raised-line and…

Spectro-temporal cues enhance modulation sensitivity in cochlear implant users

PubMed Central

Zheng, Yi; Escabí, Monty; Litovsky, Ruth Y.

2018-01-01

Although speech understanding is highly variable amongst cochlear implants (CIs) subjects, the remarkably high speech recognition performance of many CI users is unexpected and not well understood. Numerous factors, including neural health and degradation of the spectral information in the speech signal of CIs, likely contribute to speech understanding. We studied the ability to use spectro-temporal modulations, which may be critical for speech understanding and discrimination, and hypothesize that CI users adopt a different perceptual strategy than normal-hearing (NH) individuals, whereby they rely more heavily on joint spectro-temporal cues to enhance detection of auditory cues. Modulation detection sensitivity was studied in CI users and NH subjects using broadband “ripple” stimuli that were modulated spectrally, temporally, or jointly, i.e., spectro-temporally. The spectro-temporal modulation transfer functions of CI users and NH subjects was decomposed into spectral and temporal dimensions and compared to those subjects’ spectral-only and temporal-only modulation transfer functions. In CI users, the joint spectro-temporal sensitivity was better than that predicted by spectral-only and temporal-only sensitivity, indicating a heightened spectro-temporal sensitivity. Such an enhancement through the combined integration of spectral and temporal cues was not observed in NH subjects. The unique use of spectro-temporal cues by CI patients can yield benefits for use of cues that are important for speech understanding. This finding has implications for developing sound processing strategies that may rely on joint spectro-temporal modulations to improve speech comprehension of CI users, and the findings of this study may be valuable for developing clinical assessment tools to optimize CI processor performance. PMID:28601530

77 FR 29456 - City of Alameda d/b/a Alameda Belt Line Railroad-Abandonment Exemption-in Alameda County, CA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-17

.../b/a Alameda Belt Line Railroad--Abandonment Exemption--in Alameda County, CA City of Alameda d/b/a Alameda Belt Line Railroad (ABL) has filed a verified notice of exemption under 49 CFR part 1152 subpart F... traffic on the line; (3) no formal complaint filed by a user of rail service on the line (or by a state or...

Multi-Sensor Distributive On-Line Processing, Visualization, and Analysis Infrastructure for an Agricultural Information System at the NASA Goddard Earth Sciences DAAC

NASA Technical Reports Server (NTRS)

Teng, William; Berrick, Steve; Leptuokh, Gregory; Liu, Zhong; Rui, Hualan; Pham, Long; Shen, Suhung; Zhu, Tong

2004-01-01

The Goddard Space Flight Center Earth Sciences Data and Information Services Center (GES DISC) Distributed Active Center (DAAC) is developing an Agricultural Information System (AIS), evolved from an existing TRMM On-line Visualization and Analysis System precipitation and other satellite data products and services. AIS outputs will be ,integrated into existing operational decision support system for global crop monitoring, such as that of the U.N. World Food Program. The ability to use the raw data stored in the GES DAAC archives is highly dependent on having a detailed understanding of the data's internal structure and physical implementation. To gain this understanding is a time-consuming process and not a productive investment of the user's time. This is an especially difficult challenge when users need to deal with multi-sensor data that usually are of different structures and resolutions. The AIS has taken a major step towards meeting this challenge by incorporating an underlying infrastructure, called the GES-DISC Interactive Online Visualization and Analysis Infrastructure or "Giovanni," that integrates various components to support web interfaces that ,allow users to perform interactive analysis on-line without downloading any data. Several instances of the Giovanni-based interface have been or are being created to serve users of TRMM precipitation, MODIS aerosol, and SeaWiFS ocean color data, as well as agricultural applications users. Giovanni-based interfaces are simple to use but powerful. The user selects geophysical ,parameters, area of interest, and time period; and the system generates an output ,on screen in a matter of seconds.

Creating breakthroughs at 3M.

PubMed

von Hippel, E; Thomke, S; Sonnack, M

1999-01-01

Most senior managers want their product development teams to create break-throughs--new products that will allow their companies to grow rapidly and maintain high margins. But more often they get incremental improvements to existing products. That's partly because companies must compete in the short term. Searching for breakthroughs is expensive and time consuming; line extensions can help the bottom line immediately. In addition, developers simply don't know how to achieve breakthroughs, and there is usually no system in place to guide them. By the mid-1990s, the lack of such a system was a problem even for an innovative company like 3M. Then a project team in 3M's Medical-Surgical Markets Division became acquainted with a method for developing breakthrough products: the lead user process. The process is based on the fact that many commercially important products are initially thought of and even prototyped by "lead users"--companies, organizations, or individuals that are well ahead of market trends. Their needs are so far beyond those of the average user that lead users create innovations on their own that may later contribute to commercially attractive breakthroughs. The lead user process transforms the job of inventing breakthroughs into a systematic task of identifying lead users and learning from them. The authors explain the process and how the 3M project team successfully navigated through it. In the end, the team proposed three major new product lines and a change in the division's strategy that has led to the development of breakthrough products. And now several more divisions are using the process to break away from incrementalism.

Predictors of Smokeless Tobacco Abstinence

PubMed Central

Ebbert, Jon O.; Glover, Elbert; Shinozaki, Eri; Schroeder, Darrell R.; Dale, Lowell C.

2010-01-01

Objectives To investigate predictors of tobacco abstinence among smokeless tobacco (ST) users. Methods Logistic regression analyses assessed characteristics associated with tobacco abstinence among ST users receiving bupropion SR. Results Older age was associated with increased tobacco abstinence in both placebo and bupropion SR groups at end of treatment and one year. Abstinence was lower at one year for subjects with a history of major depression. At end of treatment, a 2-way interaction was detected suggesting bupropion SR may be efficacious for subjects with other household tobacco users. Conclusions Younger ST users and those with a history of depression are less likely to quit ST use. PMID:18442352

Bilateral and unilateral cochlear implant users compared on speech perception in noise.

PubMed

Dunn, Camille C; Noble, William; Tyler, Richard S; Kordus, Monika; Gantz, Bruce J; Ji, Haihong

2010-04-01

Compare speech performance in noise with matched bilateral cochlear implant (CICI) and unilateral cochlear implant (CI only) users. Thirty CICI and 30 CI-only subjects were tested on a battery of speech perception tests in noise that use an eight-loudspeaker array. On average, CICI subject's performance with speech in noise was significantly better than the CI-only subjects. The CICI group showed significantly better performance on speech perception in noise compared with the CI-only subjects, supporting the hypothesis that CICI is more beneficial than CI only.

Auditory event-related potentials in methadone substituted opiate users.

PubMed

Wang, Grace Y; Kydd, Robert; Russell, Bruce R

2015-09-01

The effects of methadone maintenance treatment (MMT) on neurophysiological function are unclear. Using an auditory oddball paradigm, event-related potential (ERP) amplitudes and latencies were measured in 32 patients undertaking MMT, 17 opiate users who were addicted but not receiving substitution treatment and 25 healthy control subjects. Compared with healthy control subjects, the MMT and opiate user groups showed an increased P200 amplitude in response to target stimuli. The opiate user group also exhibited a decreased amplitude and an increased latency of N200, and a greater number of task-related errors than either healthy control subjects or patients undertaking MMT. There were no significant group differences in the P300 amplitude. However, it is noteworthy that the frontal P300 amplitude of the MMT group was greater than that of opiate users or healthy controls. Our findings suggest that altered sensory information processing associated with a history of opiate use remains in patients undertaking MMT. However, there are less marked ERP abnormalities in those receiving MMT than in active opiate users. The deficits in information processing associated with illicit opiate use are likely to be reduced during MMT. © The Author(s) 2015.

'Fly Like This': Natural Language Interface for UAV Mission Planning

NASA Technical Reports Server (NTRS)

Chandarana, Meghan; Meszaros, Erica L.; Trujillo, Anna; Allen, B. Danette

2017-01-01

With the increasing presence of unmanned aerial vehicles (UAVs) in everyday environments, the user base of these powerful and potentially intelligent machines is expanding beyond exclusively highly trained vehicle operators to include non-expert system users. Scientists seeking to augment costly and often inflexible methods of data collection historically used are turning towards lower cost and reconfigurable UAVs. These new users require more intuitive and natural methods for UAV mission planning. This paper explores two natural language interfaces - gesture and speech - for UAV flight path generation through individual user studies. Subjects who participated in the user studies also used a mouse-based interface for a baseline comparison. Each interface allowed the user to build flight paths from a library of twelve individual trajectory segments. Individual user studies evaluated performance, efficacy, and ease-of-use of each interface using background surveys, subjective questionnaires, and observations on time and correctness. Analysis indicates that natural language interfaces are promising alternatives to traditional interfaces. The user study data collected on the efficacy and potential of each interface will be used to inform future intuitive UAV interface design for non-expert users.

Self-Reported and Judged Personality, Value, and Attitudinal Patterns: A Comparison of Users and Non Users of LSD-25.

ERIC Educational Resources Information Center

Jones, Allan P.

This study is designed to assess the benefits of LSD use as well as to examine personality, value, and attitudinal variables in order to characterize users and non users. The main assessment tool used was the in-depth interview. Subjects were 31 male and 8 female users and a non user group matched for education and age. The user was characterized…

A novel visualization model for web search results.

PubMed

Nguyen, Tien N; Zhang, Jin

2006-01-01

This paper presents an interactive visualization system, named WebSearchViz, for visualizing the Web search results and acilitating users' navigation and exploration. The metaphor in our model is the solar system with its planets and asteroids revolving around the sun. Location, color, movement, and spatial distance of objects in the visual space are used to represent the semantic relationships between a query and relevant Web pages. Especially, the movement of objects and their speeds add a new dimension to the visual space, illustrating the degree of relevance among a query and Web search results in the context of users' subjects of interest. By interacting with the visual space, users are able to observe the semantic relevance between a query and a resulting Web page with respect to their subjects of interest, context information, or concern. Users' subjects of interest can be dynamically changed, redefined, added, or deleted from the visual space.

Relationship between acceptance of background noise and hearing aid use

NASA Astrophysics Data System (ADS)

Nabelek, Anna K.; Burchfield, Samuel B.; Webster, Joanna D.

2003-04-01

Background noise produces complaints among hearing-aid users, however speech-perception-in-noise does not predict hearing-aid use. It is possible that hearing-aid users are complaining about the presence of background noise and not about speech perception. To test this possibility, acceptance of background noise is being investigated as a predictor of hearing-aid use. Acceptance of background noise is determined by having subjects select their most comfortable listening level (MCL) for a story. Next, speech-babble is added and the subjects select the maximum background noise level (BNL) which is acceptable while listening to and following the story. The difference between the MCL and the BNL is the acceptable noise level (ANL), all in dB. ANLs are being compared with hearing-aid use, subjective impressions of benefit (APHAB), speech perception in background noise (SPIN) scores, and audiometric data. Individuals who accept higher levels of background noise are more successful users than individuals who accept less background noise. Mean ANLs are 7.3 dB for full-time users (N=21), 12.6 dB for part-time users (N=44), and 13.8 dB for rejecters (N=17). ANLs are not related to APHAB, SPIN, or audiometric data. Results for about 120 subjects will be reported. [Work supported by NIDCD (NIH) RO1 DC 05018.

Monitoring User Search Success through Transaction Log Analysis: The WolfPAC Example.

ERIC Educational Resources Information Center

Zink, Steven D.

1991-01-01

Describes the use of transaction log analysis of the online catalog at the University of Nevada, Reno, libraries to help evaluate reasons for unsuccessful user searches. Author, title, and subject searches are examined; problems with Library of Congress subject headings are discussed; and title keyword searching is suggested. (11 references) (LRW)

Automated Help System For A Supercomputer

NASA Technical Reports Server (NTRS)

Callas, George P.; Schulbach, Catherine H.; Younkin, Michael

1994-01-01

Expert-system software developed to provide automated system of user-helping displays in supercomputer system at Ames Research Center Advanced Computer Facility. Users located at remote computer terminals connected to supercomputer and each other via gateway computers, local-area networks, telephone lines, and satellite links. Automated help system answers routine user inquiries about how to use services of computer system. Available 24 hours per day and reduces burden on human experts, freeing them to concentrate on helping users with complicated problems.

Operation of controls on consumer products by physically impaired users.

PubMed

Kanis, H

1993-06-01

The self-reliance of the physically impaired can be seriously jeopardized by their inability to operate everyday products, especially if both upper extremities are impaired. To determine the difficulties impaired users encounter in operating consumer product controls, on-site video recordings were made of subjects suffering from arthritis or a muscular disease. Subjects' force exertion was compared with that of a group of nonimpaired users. The resulting inventory allowed the analysis of the manipulation problems faced by impaired subjects and the development of design recommendations. In this study the force exerted by the subjects and that required to operate the controls were measured. A comparison of the results of these force measurements led to a number of conclusions. This study led to the following design recommendations: the amount of force required to operate controls should be kept as low as possible; the user should not be required to make two manipulations at the same time, such as simultaneously pushing and rotating a control device; pushing is preferable to rotating; and there should be a great degree of freedom to manipulate controls.

An interactive program to display user-generated or file-based maps on a personal computer monitor

USGS Publications Warehouse

Langer, W.H.; Stephens, R.W.

1987-01-01

PC MAP-MAKER is an ADVANCED BASIC program written to provide users of IBM XT, IBM AT, and compatible computers with a straight-forward, flexible method to display geographical data on a color or monochrome PC (personal computer) monitor. Data can be political boundaries such as State and county boundaries; natural curvilinear features such as rivers, drainage areas, and geological contacts; and points such as well locations and mineral localities. Essentially any point defined by a latitude and longitude and any line defined by a series of latitude and longitude values can be displayed using the program. PC MAP MAKER allows users to view tabular data from U.S. Geological Survey files such as WATSTORE (National Water Data Storage and Retrieval System) in a map format in a time much shorter than required by sending the data to a line plotter. The screen image can be saved to disk for recall at a later date, and hard copies can be printed with a dot matrix printer. The program is user-friendly, using menus or prompts to guide user input. It is fully documented and structured to allow the user to tailor the program to the user 's specific needs. The documentation includes a tutorial designed to introduce users to the capabilities of the program using the State of Colorado as a demonstration map area. (Author 's abstract)

The Internet as a Source of Academic Research Information: Findings of Two Pilot Studies.

ERIC Educational Resources Information Center

Kibirige, Harry M.; DePalo, Lisa

2000-01-01

Discussion of information available on the Internet focuses on two pilot studies that investigated how academic users perceive search engines and subject-oriented databases as sources of topical information. Highlights include information seeking behavior of academic users; undergraduate users; graduate users; faculty; and implications for…

Methamphetamine users show greater than normal age-related cortical gray matter loss.

PubMed

Nakama, Helenna; Chang, Linda; Fein, George; Shimotsu, Ryan; Jiang, Caroline S; Ernst, Thomas

2011-08-01

Methamphetamine (Meth) abuse continues to be a major illicit drug of abuse. Neuroimaging findings suggest that Meth is neurotoxic and may alter various brain structures, but the effect of Meth on the aging brain has not been studied. The aim was to determine regional volumes of cortical gray matter in the brains of adult Meth users versus healthy control subjects, and their interaction with age and Meth-usage variables. Cross-sectional study Magnetic resonance imaging (MRI) Research Center located in a university-affiliated hospital. Thirty-four Meth-dependent subjects (21 men and 13 women; ages 33.1 ± 8.9 years), diagnosed according to DSM-IV criteria, and 31 healthy non-Meth user comparison subjects (23 men and 8 women ages 35.7 ± 8.4 years). Regional gray matter volumes were segmented automatically in all subjects and evaluated in relation to age, using high-resolution MRIs at 3.0 Tesla. After adjustment for the effects of cranium size, the Meth users showed enhanced cortical gray matter volume loss with age in the frontal (analysis of covariance interaction P = 0.02), occipital (interaction P = 0.01), temporal (interaction P < 0.001) and the insular lobes (interaction P = 0.01) compared to controls, independently of Meth-usage patterns. Additionally, Meth users showed smaller gray matter volumes than control subjects in several subregions (dorsolateral prefrontal: P = 0.02; orbitofrontal: P = 0.03; prefrontal: P = 0.047; superior temporal: P = 0.04). Methamphetamine users appear to show increased cortical gray matter loss with age which raises the possibility of accelerated decline in mental functioning. © 2011 The Authors, Addiction © 2011 Society for the Study of Addiction.

Cybersex addiction in heterosexual female users of internet pornography can be explained by gratification hypothesis.

PubMed

Laier, Christian; Pekal, Jaro; Brand, Matthias

2014-08-01

In the context of Internet addiction, cybersex is considered to be an Internet application in which users are at risk for developing addictive usage behavior. Regarding males, experimental research has shown that indicators of sexual arousal and craving in response to Internet pornographic cues are related to severity of cybersex addiction in Internet pornography users (IPU). Since comparable investigations on females do not exist, the aim of this study is to investigate predictors of cybersex addiction in heterosexual women. We examined 51 female IPU and 51 female non-Internet pornography users (NIPU). Using questionnaires, we assessed the severity of cybersex addiction in general, as well as propensity for sexual excitation, general problematic sexual behavior, and severity of psychological symptoms. Additionally, an experimental paradigm, including a subjective arousal rating of 100 pornographic pictures, as well as indicators of craving, was conducted. Results indicated that IPU rated pornographic pictures as more arousing and reported greater craving due to pornographic picture presentation compared with NIPU. Moreover, craving, sexual arousal rating of pictures, sensitivity to sexual excitation, problematic sexual behavior, and severity of psychological symptoms predicted tendencies toward cybersex addiction in IPU. Being in a relationship, number of sexual contacts, satisfaction with sexual contacts, and use of interactive cybersex were not associated with cybersex addiction. These results are in line with those reported for heterosexual males in previous studies. Findings regarding the reinforcing nature of sexual arousal, the mechanisms of learning, and the role of cue reactivity and craving in the development of cybersex addiction in IPU need to be discussed.

Attitudinal Study of User and Non-User Teachers' towards ICT in Relation to Their School Teaching Subjects

ERIC Educational Resources Information Center

Lal, Chhavi

2014-01-01

The present study aimed to know the attitude towards ICT of user and non-user teachers of ICT. The data were collected from 40 (20 male and 20 Female) user and non-user of ICT secondary school teachers from Agra city. Attitude towards ICT was measured by Computer Attitude Scale (CAS), originally developed by Loyd and Gressard (1984). Data were…

Subjective, behavioral, and physiological effects of acute caffeine in light, nondependent caffeine users.

PubMed

Childs, Emma; de Wit, Harriet

2006-05-01

Caffeine produces mild psychostimulant effects that are thought to underlie its widespread use. However, the direct effects of caffeine are difficult to evaluate in regular users of caffeine because of tolerance and withdrawal. Indeed, some researchers hypothesize that the psychostimulant effects of caffeine are due largely to the reversal of withdrawal and question whether there are direct effects of caffeine consumption upon mood, alertness, or mental performance in nondependent individuals. This study investigated the physiological, subjective, and behavioral effects of 0, 50, 150, and 450 mg caffeine in 102 light, nondependent caffeine users. Using a within-subjects design, subjects participated in four experimental sessions, in which they received each of the four drug conditions in random order under double blind conditions. Participants completed subjective effects questionnaires and vital signs were measured before and at repeated time points after drug administration. Forty minutes after the capsules were ingested, subjects completed behavioral tasks that included tests of sustained attention, short-term memory, psychomotor performance, and behavioral inhibition. Caffeine significantly increased blood pressure, and produced feelings of arousal, positive mood, and high. Caffeine increased the number of hits and decreased reaction times in a vigilance task, but impaired performance on a memory task. We confirm that acute doses of caffeine, at levels typically found in a cup of coffee, produce stimulant-like subjective effects and enhance performance in light, nondependent caffeine users. These findings support the idea that the drug has psychoactive effects even in the absence of withdrawal.

46 CFR 190.01-5 - Vessels subject to load line.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Vessels subject to load line. 190.01-5 Section 190.01-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OCEANOGRAPHIC RESEARCH VESSELS CONSTRUCTION AND ARRANGEMENT Hull Structure § 190.01-5 Vessels subject to load line. (a) For vessels assigned a...

Perception of synchronization errors in haptic and visual communications

NASA Astrophysics Data System (ADS)

Kameyama, Seiji; Ishibashi, Yutaka

2006-10-01

This paper deals with a system which conveys the haptic sensation experimented by a user to a remote user. In the system, the user controls a haptic interface device with another remote haptic interface device while watching video. Haptic media and video of a real object which the user is touching are transmitted to another user. By subjective assessment, we investigate the allowable range and imperceptible range of synchronization error between haptic media and video. We employ four real objects and ask each subject whether the synchronization error is perceived or not for each object in the assessment. Assessment results show that we can more easily perceive the synchronization error in the case of haptic media ahead of video than in the case of the haptic media behind the video.

Prediction of user preference over shared-control paradigms for a robotic wheelchair.

PubMed

Erdogan, Ahmetcan; Argall, Brenna D

2017-07-01

The design of intelligent powered wheelchairs has traditionally focused heavily on providing effective and efficient navigation assistance. Significantly less attention has been given to the end-user's preference between different assistance paradigms. It is possible to include these subjective evaluations in the design process, for example by soliciting feedback in post-experiment questionnaires. However, constantly querying the user for feedback during real-world operation is not practical. In this paper, we present a model that correlates objective performance metrics and subjective evaluations of autonomous wheelchair control paradigms. Using off-the-shelf machine learning techniques, we show that it is possible to build a model that can predict the most preferred shared-control method from task execution metrics such as effort, safety, performance and utilization. We further characterize the relative contributions of each of these metrics to the individual choice of most preferred assistance paradigm. Our evaluation includes Spinal Cord Injured (SCI) and uninjured subject groups. The results show that our proposed correlation model enables the continuous tracking of user preference and offers the possibility of autonomy that is customized to each user.

Collection development using interlibrary loan borrowing and acquisitions statistics.

PubMed Central

Byrd, G D; Thomas, D A; Hughes, K E

1982-01-01

Libraries, especially those supporting the sciences, continually face the problem of selecting appropriate new books for their users. Traditional collection development techniques include the use of librarian or user subject specialists, user recommendations, and approval plans. These methods of selection, however, are most effective in large libraries and do not systemically correlate new book purchases with the actual demands of users served. This paper describes a statistical method for determining subject strengths and weaknesses in a library book collection in relation to user demand. Using interlibrary loan borrowing and book acquisition statistics gathered for one fiscal year from three health sciences libraries, the authors developed a way to graph the broad and narrow subject fields of strength and potential weakness in a book collection. This method has the advantages of simplicity, speed of implementation, and clarity. It can also be used over a period of time to verify the success or failure of a collection development program. Finally, the method has potential as a tool for use by two or more libraries seeking to improve cooperative collection development in a network or consortium. PMID:7059712

User-guided segmentation for volumetric retinal optical coherence tomography images

PubMed Central

Yin, Xin; Chao, Jennifer R.; Wang, Ruikang K.

2014-01-01

Abstract. Despite the existence of automatic segmentation techniques, trained graders still rely on manual segmentation to provide retinal layers and features from clinical optical coherence tomography (OCT) images for accurate measurements. To bridge the gap between this time-consuming need of manual segmentation and currently available automatic segmentation techniques, this paper proposes a user-guided segmentation method to perform the segmentation of retinal layers and features in OCT images. With this method, by interactively navigating three-dimensional (3-D) OCT images, the user first manually defines user-defined (or sketched) lines at regions where the retinal layers appear very irregular for which the automatic segmentation method often fails to provide satisfactory results. The algorithm is then guided by these sketched lines to trace the entire 3-D retinal layer and anatomical features by the use of novel layer and edge detectors that are based on robust likelihood estimation. The layer and edge boundaries are finally obtained to achieve segmentation. Segmentation of retinal layers in mouse and human OCT images demonstrates the reliability and efficiency of the proposed user-guided segmentation method. PMID:25147962

Does the Type of Event Influence How User Interactions Evolve on Twitter?

PubMed Central

del Val, Elena; Rebollo, Miguel; Botti, Vicente

2015-01-01

The number of people using on-line social networks as a new way of communication is continually increasing. The messages that a user writes in these networks and his/her interactions with other users leave a digital trace that is recorded. Thanks to this fact and the use of network theory, the analysis of messages, user interactions, and the complex structures that emerge is greatly facilitated. In addition, information generated in on-line social networks is labeled temporarily, which makes it possible to go a step further analyzing the dynamics of the interaction patterns. In this article, we present an analysis of the evolution of user interactions that take place in television, socio-political, conference, and keynote events on Twitter. Interactions have been modeled as networks that are annotated with the time markers. We study changes in the structural properties at both the network level and the node level. As a result of this analysis, we have detected patterns of network evolution and common structural features as well as differences among the events. PMID:25961305

User-guided segmentation for volumetric retinal optical coherence tomography images.

PubMed

Yin, Xin; Chao, Jennifer R; Wang, Ruikang K

2014-08-01

Despite the existence of automatic segmentation techniques, trained graders still rely on manual segmentation to provide retinal layers and features from clinical optical coherence tomography (OCT) images for accurate measurements. To bridge the gap between this time-consuming need of manual segmentation and currently available automatic segmentation techniques, this paper proposes a user-guided segmentation method to perform the segmentation of retinal layers and features in OCT images. With this method, by interactively navigating three-dimensional (3-D) OCT images, the user first manually defines user-defined (or sketched) lines at regions where the retinal layers appear very irregular for which the automatic segmentation method often fails to provide satisfactory results. The algorithm is then guided by these sketched lines to trace the entire 3-D retinal layer and anatomical features by the use of novel layer and edge detectors that are based on robust likelihood estimation. The layer and edge boundaries are finally obtained to achieve segmentation. Segmentation of retinal layers in mouse and human OCT images demonstrates the reliability and efficiency of the proposed user-guided segmentation method.

A hypertext system that learns from user feedback

NASA Technical Reports Server (NTRS)

Mathe, Nathalie

1994-01-01

Retrieving specific information from large amounts of documentation is not an easy task. It could be facilitated if information relevant in the current problem solving context could be automatically supplied to the user. As a first step towards this goal, we have developed an intelligent hypertext system called CID (Computer Integrated Documentation). Besides providing an hypertext interface for browsing large documents, the CID system automatically acquires and reuses the context in which previous searches were appropriate. This mechanism utilizes on-line user information requirements and relevance feedback either to reinforce current indexing in case of success or to generate new knowledge in case of failure. Thus, the user continually augments and refines the intelligence of the retrieval system. This allows the CID system to provide helpful responses, based on previous usage of the documentation, and to improve its performance over time. We successfully tested the CID system with users of the Space Station Freedom requirements documents. We are currently extending CID to other application domains (Space Shuttle operations documents, airplane maintenance manuals, and on-line training). We are also exploring the potential commercialization of this technique.

Kameleon Live: An Interactive Cloud Based Analysis and Visualization Platform for Space Weather Researchers

NASA Astrophysics Data System (ADS)

Pembroke, A. D.; Colbert, J. A.

2015-12-01

The Community Coordinated Modeling Center (CCMC) provides hosting for many of the simulations used by the space weather community of scientists, educators, and forecasters. CCMC users may submit model runs through the Runs on Request system, which produces static visualizations of model output in the browser, while further analysis may be performed off-line via Kameleon, CCMC's cross-language access and interpolation library. Off-line analysis may be suitable for power-users, but storage and coding requirements present a barrier to entry for non-experts. Moreover, a lack of a consistent framework for analysis hinders reproducibility of scientific findings. To that end, we have developed Kameleon Live, a cloud based interactive analysis and visualization platform. Kameleon Live allows users to create scientific studies built around selected runs from the Runs on Request database, perform analysis on those runs, collaborate with other users, and disseminate their findings among the space weather community. In addition to showcasing these novel collaborative analysis features, we invite feedback from CCMC users as we seek to advance and improve on the new platform.

Off-Line Catalog Production.

ERIC Educational Resources Information Center

OCLC Online Computer Library Center, Inc., Dublin, OH.

The Ohio College Library Center's off-line catalog system is a limited technique for production of card catalogs. Unlike the on-line system, it cannotmake the resources of a region available to users in an individual institution, and it does not have the potential for significantly reducing rate of rise of library per-unit costs. In short, it is…

GrayStarServer: Server-side Spectrum Synthesis with a Browser-based Client-side User Interface

NASA Astrophysics Data System (ADS)

Short, C. Ian

2016-10-01

We present GrayStarServer (GSS), a stellar atmospheric modeling and spectrum synthesis code of pedagogical accuracy that is accessible in any web browser on commonplace computational devices and that runs on a timescale of a few seconds. The addition of spectrum synthesis annotated with line identifications extends the functionality and pedagogical applicability of GSS beyond that of its predecessor, GrayStar3 (GS3). The spectrum synthesis is based on a line list acquired from the NIST atomic spectra database, and the GSS post-processing and user interface client allows the user to inspect the plain text ASCII version of the line list, as well as to apply macroscopic broadening. Unlike GS3, GSS carries out the physical modeling on the server side in Java, and communicates with the JavaScript and HTML client via an asynchronous HTTP request. We also describe other improvements beyond GS3 such as a more physical treatment of background opacity and atmospheric physics, the comparison of key results with those of the Phoenix code, and the use of the HTML < {canvas}> element for higher quality plotting and rendering of results. We also present LineListServer, a Java code for converting custom ASCII line lists in NIST format to the byte data type file format required by GSS so that users can prepare their own custom line lists. We propose a standard for marking up and packaging model atmosphere and spectrum synthesis output for data transmission and storage that will facilitate a web-based approach to stellar atmospheric modeling and spectrum synthesis. We describe some pedagogical demonstrations and exercises enabled by easily accessible, on-demand, responsive spectrum synthesis. GSS may serve as a research support tool by providing quick spectroscopic reconnaissance. GSS may be found at www.ap.smu.ca/~ishort/OpenStars/GrayStarServer/grayStarServer.html, and source tarballs for local installations of both GSS and LineListServer may be found at www.ap.smu.ca/~ishort/OpenStars/.

AITRAC: Augmented Interactive Transient Radiation Analysis by Computer. User's information manual

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1977-10-01

AITRAC is a program designed for on-line, interactive, DC, and transient analysis of electronic circuits. The program solves linear and nonlinear simultaneous equations which characterize the mathematical models used to predict circuit response. The program features 100 external node--200 branch capability; conversional, free-format input language; built-in junction, FET, MOS, and switch models; sparse matrix algorithm with extended-precision H matrix and T vector calculations, for fast and accurate execution; linear transconductances: beta, GM, MU, ZM; accurate and fast radiation effects analysis; special interface for user-defined equations; selective control of multiple outputs; graphical outputs in wide and narrow formats; and on-line parametermore » modification capability. The user describes the problem by entering the circuit topology and part parameters. The program then automatically generates and solves the circuit equations, providing the user with printed or plotted output. The circuit topology and/or part values may then be changed by the user, and a new analysis, requested. Circuit descriptions may be saved on disk files for storage and later use. The program contains built-in standard models for resistors, voltage and current sources, capacitors, inductors including mutual couplings, switches, junction diodes and transistors, FETS, and MOS devices. Nonstandard models may be constructed from standard models or by using the special equations interface. Time functions may be described by straight-line segments or by sine, damped sine, and exponential functions. 42 figures, 1 table. (RWR)« less

7 CFR 500.25 - Payment of fees.

Code of Federal Regulations, 2010 CFR

2010-01-01

... enters into an agreement to allow USNA visitors and users to make payment in the form of a credit card, USNA visitors and users who are assessed user fees may pay those fees with a credit card subject to the...

7 CFR 500.25 - Payment of fees.

Code of Federal Regulations, 2013 CFR

2013-01-01

... enters into an agreement to allow USNA visitors and users to make payment in the form of a credit card, USNA visitors and users who are assessed user fees may pay those fees with a credit card subject to the...

7 CFR 500.25 - Payment of fees.

Code of Federal Regulations, 2014 CFR

2014-01-01

... enters into an agreement to allow USNA visitors and users to make payment in the form of a credit card, USNA visitors and users who are assessed user fees may pay those fees with a credit card subject to the...

7 CFR 500.25 - Payment of fees.

Code of Federal Regulations, 2011 CFR

2011-01-01

... enters into an agreement to allow USNA visitors and users to make payment in the form of a credit card, USNA visitors and users who are assessed user fees may pay those fees with a credit card subject to the...

7 CFR 500.25 - Payment of fees.

Code of Federal Regulations, 2012 CFR

2012-01-01

... enters into an agreement to allow USNA visitors and users to make payment in the form of a credit card, USNA visitors and users who are assessed user fees may pay those fees with a credit card subject to the...

Education and Training for On-Line Use of Data Bases

ERIC Educational Resources Information Center

Williams, Martha E.

1977-01-01

This paper discusses vehicles for education and training, tools and techniques for promotion, and details the information requirements of the processors, service managers, searchers, and end users of on-line data bases. (Author/KP)

AFTER: Batch jobs on the Apollo ring

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hofstadler, P.

1987-07-01

This document describes AFTER, a system that allows users of an Apollo ring to submit batch jobs to run without leaving themselves logged in to the ring. Jobs may be submitted to run at a later time or on a different node. Results from the batch job are mailed to the user through some designated mail system. AFTER features an understandable user interface, good on line help, and site customization. This manual serves primarily as a user's guide to AFTER although administration and installation are covered for completeness.

Model Description and Proposed Application for the Enlisted Personnel Inventory, Cost, and Compensation Model

DTIC Science & Technology

1994-07-01

provide additional information for the user / policy analyst: Eichers, D., Sola, M., McLernan, G., EPICC User’s Manual , Systems Research and Applications...maintenance, and a set of on-line help screens. Each are further discussed below and a full discussion is included in the EPICC User’s Manual . Menu Based...written documentation (user’s manual ) that will be provided with the model. 55 The next chapter discusses the validation of the inventory projection and

Discovery of User-Oriented Class Associations for Enriching Library Classification Schemes.

ERIC Educational Resources Information Center

Pu, Hsiao-Tieh

2002-01-01

Presents a user-based approach to exploring the possibility of adding user-oriented class associations to hierarchical library classification schemes. Classes not grouped in the same subject hierarchies yet relevant to users' knowledge are obtained by analyzing a log book of a university library's circulation records, using collaborative filtering…

Feasibility of BCI Control in a Realistic Smart Home Environment.

PubMed

Kosmyna, Nataliya; Tarpin-Bernard, Franck; Bonnefond, Nicolas; Rivet, Bertrand

2016-01-01

Smart homes have been an active area of research, however despite considerable investment, they are not yet a reality for end-users. Moreover, there are still accessibility challenges for the elderly or the disabled, two of the main potential targets for home automation. In this exploratory study we design a control mechanism for smart homes based on Brain Computer Interfaces (BCI) and apply it in the "Domus" smart home platform in order to evaluate the potential interest of users about BCIs at home. We enable users to control lighting, a TV set, a coffee machine and the shutters of the smart home. We evaluate the performance (accuracy, interaction time), usability and feasibility (USE questionnaire) on 12 healthy subjects and 2 disabled subjects. We find that healthy subjects achieve 77% task accuracy. However, disabled subjects achieved a better accuracy (81% compared to 77%).

Towards an Explanation of Subjective Ketamine Experiences among Young Injection Drug Users

PubMed Central

LANKENAU, STEPHEN E.; SANDERS, BILL; BLOOM, JENNIFER JACKSON; HATHAZI, DODI

2008-01-01

Ketamine is a dissociative anesthetic with powerful sedative and hallucinogenic properties. Despite the wide variability in reported subjective experiences, no study has attempted to describe the particular factors that shape these experiences. This manuscript is based upon a sample of 213 young injection drug users recruited in New York, New Orleans, and Los Angeles with histories of ketamine use. Qualitative interviews focused on specific ketamine events, such as first injection of ketamine, most recent injection of ketamine, and most recent experience sniffing ketamine. Findings indicate that six factors impacted both positive and negative ketamine experiences: polydrug use, drug using history, mode of administration, quantity and quality of ketamine, user group, and setting. Most subjective experiences during any given ketamine event were shaped by a combination of these factors. Additionally, subjective ketamine experiences were particularly influenced by a lifestyle characterized by homelessness and traveling. PMID:18941540

Feasibility of BCI Control in a Realistic Smart Home Environment

PubMed Central

Kosmyna, Nataliya; Tarpin-Bernard, Franck; Bonnefond, Nicolas; Rivet, Bertrand

2016-01-01

Smart homes have been an active area of research, however despite considerable investment, they are not yet a reality for end-users. Moreover, there are still accessibility challenges for the elderly or the disabled, two of the main potential targets for home automation. In this exploratory study we design a control mechanism for smart homes based on Brain Computer Interfaces (BCI) and apply it in the “Domus”1 smart home platform in order to evaluate the potential interest of users about BCIs at home. We enable users to control lighting, a TV set, a coffee machine and the shutters of the smart home. We evaluate the performance (accuracy, interaction time), usability and feasibility (USE questionnaire) on 12 healthy subjects and 2 disabled subjects. We find that healthy subjects achieve 77% task accuracy. However, disabled subjects achieved a better accuracy (81% compared to 77%). PMID:27616986

Requirements UML Tool (RUT) Expanded for Extreme Programming (CI02)

NASA Technical Reports Server (NTRS)

McCoy, James R.

2003-01-01

A procedure for capturing and managing system requirements that incorporates XP user stories. Because costs associated with identifying problems in requirements increase dramatically over the lifecycle of a project, a method for identifying sources of software risks in user stories is urgently needed. This initiative aims to determine a set of guide-lines for user stories that will result in high-quality requirement. To further this initiative, a tool is needed to analyze user stories that can assess the quality of individual user stories, detect sources cf software risk's, produce software metrics, and identify areas in user stories that can be improved.

CellSegm - a MATLAB toolbox for high-throughput 3D cell segmentation

PubMed Central

2013-01-01

The application of fluorescence microscopy in cell biology often generates a huge amount of imaging data. Automated whole cell segmentation of such data enables the detection and analysis of individual cells, where a manual delineation is often time consuming, or practically not feasible. Furthermore, compared to manual analysis, automation normally has a higher degree of reproducibility. CellSegm, the software presented in this work, is a Matlab based command line software toolbox providing an automated whole cell segmentation of images showing surface stained cells, acquired by fluorescence microscopy. It has options for both fully automated and semi-automated cell segmentation. Major algorithmic steps are: (i) smoothing, (ii) Hessian-based ridge enhancement, (iii) marker-controlled watershed segmentation, and (iv) feature-based classfication of cell candidates. Using a wide selection of image recordings and code snippets, we demonstrate that CellSegm has the ability to detect various types of surface stained cells in 3D. After detection and outlining of individual cells, the cell candidates can be subject to software based analysis, specified and programmed by the end-user, or they can be analyzed by other software tools. A segmentation of tissue samples with appropriate characteristics is also shown to be resolvable in CellSegm. The command-line interface of CellSegm facilitates scripting of the separate tools, all implemented in Matlab, offering a high degree of flexibility and tailored workflows for the end-user. The modularity and scripting capabilities of CellSegm enable automated workflows and quantitative analysis of microscopic data, suited for high-throughput image based screening. PMID:23938087

CellSegm - a MATLAB toolbox for high-throughput 3D cell segmentation.

PubMed

Hodneland, Erlend; Kögel, Tanja; Frei, Dominik Michael; Gerdes, Hans-Hermann; Lundervold, Arvid

2013-08-09

: The application of fluorescence microscopy in cell biology often generates a huge amount of imaging data. Automated whole cell segmentation of such data enables the detection and analysis of individual cells, where a manual delineation is often time consuming, or practically not feasible. Furthermore, compared to manual analysis, automation normally has a higher degree of reproducibility. CellSegm, the software presented in this work, is a Matlab based command line software toolbox providing an automated whole cell segmentation of images showing surface stained cells, acquired by fluorescence microscopy. It has options for both fully automated and semi-automated cell segmentation. Major algorithmic steps are: (i) smoothing, (ii) Hessian-based ridge enhancement, (iii) marker-controlled watershed segmentation, and (iv) feature-based classfication of cell candidates. Using a wide selection of image recordings and code snippets, we demonstrate that CellSegm has the ability to detect various types of surface stained cells in 3D. After detection and outlining of individual cells, the cell candidates can be subject to software based analysis, specified and programmed by the end-user, or they can be analyzed by other software tools. A segmentation of tissue samples with appropriate characteristics is also shown to be resolvable in CellSegm. The command-line interface of CellSegm facilitates scripting of the separate tools, all implemented in Matlab, offering a high degree of flexibility and tailored workflows for the end-user. The modularity and scripting capabilities of CellSegm enable automated workflows and quantitative analysis of microscopic data, suited for high-throughput image based screening.

Bilateral and Unilateral Cochlear Implant Users Compared on Speech Perception in Noise

PubMed Central

Dunn, Camille C.; Noble, William; Tyler, Richard S.; Kordus, Monika; Gantz, Bruce J.; Ji, Haihong

2009-01-01

Objective Compare speech performance in noise with matched bilateral (CICI) and unilateral (CI-Only) cochlear implant users. Design Thirty CICI and 30 CI-Only subjects were tested on a battery of speech perception tests in noise that utilize an 8-loudspeaker array. Results On average, CICI subject's performance with speech in noise was significantly better than the CI-Only subjects. Conclusion The CICI group showed significantly better performance on speech perception in noise compared to the CI-Only subjects, supporting the hypothesis that bilateral cochlear implantation is more beneficial than unilateral implantation. PMID:19858720

Improvement of a uniqueness-and-anonymity-preserving user authentication scheme for connected health care.

PubMed

Xie, Qi; Liu, Wenhao; Wang, Shengbao; Han, Lidong; Hu, Bin; Wu, Ting

2014-09-01

Patient's privacy-preserving, security and mutual authentication between patient and the medical server are the important mechanism in connected health care applications, such as telecare medical information systems and personally controlled health records systems. In 2013, Wen showed that Das et al.'s scheme is vulnerable to the replay attack, user impersonation attacks and off-line guessing attacks, and then proposed an improved scheme using biometrics, password and smart card to overcome these weaknesses. However, we show that Wen's scheme is still vulnerable to off-line password guessing attacks, does not provide user's anonymity and perfect forward secrecy. Further, we propose an improved scheme to fix these weaknesses, and use the applied pi calculus based formal verification tool ProVerif to prove the security and authentication.

MAGENCO: A map generalization controller for Arc/Info

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ganter, J.H.; Cashwell, J.W.

The Arc/Info GENERALIZE command implements the Douglas-Peucker algorithm, a well-regarded approach that preserves line ``character`` while reducing the number of points according to a tolerance parameter supplied by the user. The authors have developed an Arc Macro Language (AML) interface called MAGENCO that allows the user to browse workspaces, select a coverage, extract a sample from this coverage, then apply various tolerances to the sample. The results are shown in multiple display windows that are arranged around the original sample for quick visual comparison. The user may then return to the whole coverage and apply the chosen tolerance. They analyzemore » the ergonomics of line simplification, explain the design (which includes an animated demonstration of the Douglas-Peucker algorithm), and discuss key points of the MAGENCO implementation.« less

Student Preferences toward Microcomputer User Interfaces.

ERIC Educational Resources Information Center

Hazari, Sunil I.; Reaves, Rita R.

1994-01-01

Describes a study of undergraduates that was conducted to determine students' preferences toward Graphical User Interface versus Command Line Interface during computer-assisted instruction. Previous experience, comfort level, performance scores, and student attitudes are examined and compared, and the computer use survey is appended. (Contains 13…

Are Microsoft's Animated Interface Agents Helpful?

ERIC Educational Resources Information Center

Head, Allison J.

1998-01-01

Discusses interface agents and online help systems, focusing on Microsoft's animated office assistants. Highlights include intermediaries such as librarians in off-line reference problems; user complaints about online help systems; navigation problems; evaluation of the online office assistants; and categories of user queries to online help…

Comparison of Accuracy and Speed of Information Identification by Nonpathologists in Synoptic Reports With Different Formats.

PubMed

Renshaw, Andrew A; Gould, Edwin W

2017-03-01

- The College of American Pathologists requires synoptic reports for specific types of pathology reports. - To compare the accuracy and speed of information retrieval in synoptic reports of different formats. - We assessed the performance of 28 nonpathologists from 4 different types of users (cancer registrars, MDs, medical non-MDs, and nonmedical) at identifying specific information in various formatted synoptic reports, using a computerized quiz that measured both accuracy and speed. - There was no significant difference in the accuracy of data identification for any user group or in any format. While there were significant differences in raw time between users, these were eliminated when normalized times were used. Compared with the standard format of a required data element (RDE) and response on 1 line, both a list of responses without an RDE (21%, P < .001) and a paired response with more concise text (33%, P < .001) were significantly faster. In contrast, both the 2-line format (RDE header on one line, response indented on the second line) (12%, P < .001) and a report with the RDE response pairs in a random order were significantly slower (16%, P < .001). - There are significant differences in ease of use by nonpathologists between different synoptic report formats. Such information may be useful in deciding between different format options.

Intelligent data management

NASA Technical Reports Server (NTRS)

Campbell, William J.

1985-01-01

Intelligent data management is the concept of interfacing a user to a database management system with a value added service that will allow a full range of data management operations at a high level of abstraction using human written language. The development of such a system will be based on expert systems and related artificial intelligence technologies, and will allow the capturing of procedural and relational knowledge about data management operations and the support of a user with such knowledge in an on-line, interactive manner. Such a system will have the following capabilities: (1) the ability to construct a model of the users view of the database, based on the query syntax; (2) the ability to transform English queries and commands into database instructions and processes; (3) the ability to use heuristic knowledge to rapidly prune the data space in search processes; and (4) the ability to use an on-line explanation system to allow the user to understand what the system is doing and why it is doing it. Additional information is given in outline form.

Comparative analysis of data base management systems

NASA Technical Reports Server (NTRS)

Smith, R.

1983-01-01

A study to determine if the Remote File Inquiry (RFI) system would handle the future requirements of the user community is discussed. RFI is a locally written and locally maintained on-line query/update package. The current and future on-line requirements of the user community were studied. Additional consideration was given to the types of data structuring the users required. The survey indicated the features of greatest benefit were: sort, subtotals, totals, record selection, storage of queries, global updating and the ability to page break. The major deficiencies were: one level of hierarchy, excessive response time, software unreliability, difficult to add, delete and modify records, complicated error messages and the lack of ability to perform interfield comparisons. Missing features users required were: formatted screens, interfield comparions, interfield arithmetic, multiple file access, security and data integrity. The survey team recommended Kennedy Space Center move forward to state-of-the-art software, a Data Base Management System which is thoroughly tested and easy to implement and use.

JEDI Transmission Line Model | Jobs and Economic Development Impact Models

Science.gov Websites

, reasonable default values are provided. Individual projects may vary and when possible, project specific data Line Model rel. TL12.23.16. JEDI Transmission Line Model User Reference Guide Using MS Excel 2007 When ;High." Set the level to "Medium" or "Low" and then re-open the JEDI worksheet

Competencies of Front-Line Managers in Supported Accommodation: Issues for Practice and Future Research

ERIC Educational Resources Information Center

Clement, Tim; Bigby, Christine

2012-01-01

Background: Front-line managers of supported accommodation for people with intellectual disability are assumed to have a key role in the realisation of outcomes for service users. Yet, their job has been little researched. A job analysis from Minnesota that identified 142 competencies required of effective front-line managers was used to examine…

Interaction Between Functional Genetic Variation of DRD2 and Cannabis Use on Risk of Psychosis.

PubMed

Colizzi, Marco; Iyegbe, Conrad; Powell, John; Ursini, Gianluca; Porcelli, Annamaria; Bonvino, Aurora; Taurisano, Paolo; Romano, Raffaella; Masellis, Rita; Blasi, Giuseppe; Morgan, Craig; Aitchison, Katherine; Mondelli, Valeria; Luzi, Sonija; Kolliakou, Anna; David, Anthony; Murray, Robin M; Bertolino, Alessandro; Di Forti, Marta

2015-09-01

Both cannabis use and the dopamine receptor (DRD2) gene have been associated with schizophrenia, psychosis-like experiences, and cognition. However, there are no published data investigating whether genetically determined variation in DRD2 dopaminergic signaling might play a role in individual susceptibility to cannabis-associated psychosis. We genotyped (1) a case-control study of 272 patients with their first episode of psychosis and 234 controls, and also from (2) a sample of 252 healthy subjects, for functional variation in DRD2, rs1076560. Data on history of cannabis use were collected on all the studied subjects by administering the Cannabis Experience Questionnaire. In the healthy subjects' sample, we also collected data on schizotypy and cognitive performance using the Schizotypal Personality Questionnaire and the N-back working memory task. In the case-control study, we found a significant interaction between the rs1076560 DRD2 genotype and cannabis use in influencing the likelihood of a psychotic disorder. Among cannabis users, carriers of the DRD2, rs1076560, T allele showed a 3-fold increased probability to suffer a psychotic disorder compared with GG carriers (OR = 3.07; 95% confidence interval [CI]: 1.22-7.63). Among daily users, T carrying subjects showed a 5-fold increase in the odds of psychosis compared to GG carriers (OR = 4.82; 95% CI: 1.39-16.71). Among the healthy subjects, T carrying cannabis users had increased schizotypy compared with T carrying cannabis-naïve subjects, GG cannabis users, and GG cannabis-naïve subjects (all P ≤ .025). T carrying cannabis users had reduced working memory accuracy compared with the other groups (all P ≤ .008). Thus, variation of the DRD2, rs1076560, genotype may modulate the psychosis-inducing effect of cannabis use. © The Author 2015. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oup.com.

User's Self-Prediction of Performance in Motor Imagery Brain-Computer Interface.

PubMed

Ahn, Minkyu; Cho, Hohyun; Ahn, Sangtae; Jun, Sung C

2018-01-01

Performance variation is a critical issue in motor imagery brain-computer interface (MI-BCI), and various neurophysiological, psychological, and anatomical correlates have been reported in the literature. Although the main aim of such studies is to predict MI-BCI performance for the prescreening of poor performers, studies which focus on the user's sense of the motor imagery process and directly estimate MI-BCI performance through the user's self-prediction are lacking. In this study, we first test each user's self-prediction idea regarding motor imagery experimental datasets. Fifty-two subjects participated in a classical, two-class motor imagery experiment and were asked to evaluate their easiness with motor imagery and to predict their own MI-BCI performance. During the motor imagery experiment, an electroencephalogram (EEG) was recorded; however, no feedback on motor imagery was given to subjects. From EEG recordings, the offline classification accuracy was estimated and compared with several questionnaire scores of subjects, as well as with each subject's self-prediction of MI-BCI performance. The subjects' performance predictions during motor imagery task showed a high positive correlation ( r = 0.64, p < 0.01). Interestingly, it was observed that the self-prediction became more accurate as the subjects conducted more motor imagery tasks in the Correlation coefficient (pre-task to 2nd run: r = 0.02 to r = 0.54, p < 0.01) and root mean square error (pre-task to 3rd run: 17.7% to 10%, p < 0.01). We demonstrated that subjects may accurately predict their MI-BCI performance even without feedback information. This implies that the human brain is an active learning system and, by self-experiencing the endogenous motor imagery process, it can sense and adopt the quality of the process. Thus, it is believed that users may be able to predict MI-BCI performance and results may contribute to a better understanding of low performance and advancing BCI.

HYC-24L Demonstrates Greater Effectiveness With Less Pain Than CPM-22.5 for Treatment of Perioral Lines in a Randomized Controlled Trial.

PubMed

Butterwick, Kimberly; Marmur, Ellen; Narurkar, Vic; Cox, Sue Ellen; Joseph, John H; Sadick, Neil S; Tedaldi, Ruth; Wheeler, Sarah; Kolodziejczyk, Julia K; Gallagher, Conor J

2015-12-01

This trial compares the effectiveness and safety of HYC-24L (Juvéderm Ultra XC; Allergan plc, Dublin, Ireland) (24 mg/mL of hyaluronic acid, 0.3% lidocaine) and CPM-22.5 (Belotero Balance; Merz Aesthetics, Raleigh, NC) (22.5 mg/mL of hyaluronic acid) for the treatment of perioral lines. Men and women aged 35 years or older with moderate-to-severe perioral lines were recruited for this randomized controlled, rater-blinded, 2-arm trial. The primary endpoint was a comparison of rater-assessed responder rates by the validated 4-point Perioral Lines Severity Scale at Month 6; responders were those who showed a ≥1 point improvement. A secondary endpoint was subject-assessed change in perioral lines measured by the Global Assessment of Change Scale. A total of 136 subjects received treatment and 132 completed the trial (mean age: 58 ± 8 years). Total volume injected was 1.18 mL (HYC-24L) and 1.32 mL (CPM-22.5). At Month 6, a significantly greater proportion of HYC-24L subjects responded to treatment (87%) than CPM-22.5 subjects (72%) (p < .04). At all time points, HYC-24L subjects reported significantly greater improvement in their perioral lines than CPM-22.5 subjects, with the greatest difference at Month 6. No unexpected adverse events occurred. HYC-24L subjects showed a higher response rate and a greater improvement in their perioral lines than CPM-22.5 subjects for up to 6 months.

MADS Users' Guide

NASA Technical Reports Server (NTRS)

Moerder, Daniel D.

2014-01-01

MADS (Minimization Assistant for Dynamical Systems) is a trajectory optimization code in which a user-specified performance measure is directly minimized, subject to constraints placed on a low-order discretization of user-supplied plant ordinary differential equations. This document describes the mathematical formulation of the set of trajectory optimization problems for which MADS is suitable, and describes the user interface. Usage examples are provided.

Differentiating Characteristics of Juvenile Methamphetamine Users

ERIC Educational Resources Information Center

Fass, Daniel; Calhoun, Georgia B.; Glaser, Brian A.; Yanosky, Daniel J., II

2009-01-01

The authors investigated the differences in characteristics and risk behaviors endorsed by detained adolescent methamphetamine users and compared them with other drug users. Subjects completed the Millon Adolescent Clinical Inventory and a questionnaire in which sociodemographics and behavioral information were explored and compared. Multivariate…

The Teaching of User Studies as a Subject for the Preparation of Librarians, Documentalists, Archivists and Other Information Specialists.

ERIC Educational Resources Information Center

Sene, H.

This working paper focuses on methods for developing a study program on scientific and technical information users that could serve as a subject of study in the academic preparation of librarians, archivists, and scientific and technical information specialists. Recognizing that in most schools for training specialists of scientific and technical…

Association of dopamine transporter loss in the orbitofrontal and dorsolateral prefrontal cortices with methamphetamine-related psychiatric symptoms.

PubMed

Sekine, Yoshimoto; Minabe, Yoshio; Ouchi, Yasuomi; Takei, Nori; Iyo, Masaomi; Nakamura, Kazuhiko; Suzuki, Katsuaki; Tsukada, Hideo; Okada, Hiroyuki; Yoshikawa, Etsuji; Futatsubashi, Masami; Mori, Norio

2003-09-01

The authors examined dopamine transporter density in the orbitofrontal cortex, dorsolateral prefrontal cortex, and amygdala in methamphetamine users and assessed the relationship of these measures to the subjects' clinical characteristics. Positron emission tomography with [(11)C]WIN 35,428 was used to examine the regions of interest in 11 methamphetamine users and nine healthy comparison subjects. Psychiatric symptoms were evaluated with the Brief Psychiatric Rating Scale. Dopamine transporter density in the three regions studied was significantly lower in the methamphetamine users than in the comparison subjects. The lower dopamine transporter density in the orbitofrontal and dorsolateral prefrontal cortex was significantly correlated with the duration of methamphetamine use and the severity of psychiatric symptoms. Chronic methamphetamine use may cause dopamine transporter reduction in the orbitofrontal cortex, dorsolateral prefrontal cortex, and amygdala in the brain. Psychiatric symptoms in methamphetamine users may be attributable to the decrease in dopamine transporter density in the orbitofrontal cortex and the dorsolateral prefrontal cortex.

Automating testbed documentation and database access using World Wide Web (WWW) tools

NASA Technical Reports Server (NTRS)

Ames, Charles; Auernheimer, Brent; Lee, Young H.

1994-01-01

A method for providing uniform transparent access to disparate distributed information systems was demonstrated. A prototype testing interface was developed to access documentation and information using publicly available hypermedia tools. The prototype gives testers a uniform, platform-independent user interface to on-line documentation, user manuals, and mission-specific test and operations data. Mosaic was the common user interface, and HTML (Hypertext Markup Language) provided hypertext capability.

PDS: A Performance Database Server

DOE PAGES

Berry, Michael W.; Dongarra, Jack J.; Larose, Brian H.; ...

1994-01-01

The process of gathering, archiving, and distributing computer benchmark data is a cumbersome task usually performed by computer users and vendors with little coordination. Most important, there is no publicly available central depository of performance data for all ranges of machines from personal computers to supercomputers. We present an Internet-accessible performance database server (PDS) that can be used to extract current benchmark data and literature. As an extension to the X-Windows-based user interface (Xnetlib) to the Netlib archival system, PDS provides an on-line catalog of public domain computer benchmarks such as the LINPACK benchmark, Perfect benchmarks, and the NAS parallelmore » benchmarks. PDS does not reformat or present the benchmark data in any way that conflicts with the original methodology of any particular benchmark; it is thereby devoid of any subjective interpretations of machine performance. We believe that all branches (research laboratories, academia, and industry) of the general computing community can use this facility to archive performance metrics and make them readily available to the public. PDS can provide a more manageable approach to the development and support of a large dynamic database of published performance metrics.« less

[The use of interviews in participative intervention and research: the GAM tool as a collective interview].

PubMed

Sade, Christian; de Barros, Leticia Maria Renault; Melo, Jorge José Maciel; Passos, Eduardo

2013-10-01

This paper seeks to assess a way of conducting interviews in line with the ideology of Brazilian Psychiatric Reform. In the methodology of participative intervention and research in mental health, the interview is less a data collection than a data harvesting procedure. It is designed to apply the principles of psychosocial care, autonomy as the basis for treatment, the predominance of the users and of their social networks and civic participation. Inspired by the Explicitation Interview technique, the contention is that the handling of the interview presupposes an open attitude able to promote and embrace different viewpoints. This attitude makes the interview a collective experience of sharing and belonging, allowing participants to reposition themselves subjectively in treatment with the emergence of groupality. As an example of using the interview as a methodological tool in mental health research, we examine research into adaptation of the tool of Autonomous Medication Management (GAM). It is an interventionist approach guided by principles that foster autonomy and the protagonist status of users of psychotropic medication, their quality of life, their rights and recognition of the multiple significances of medication, understood here as a collective interview technique.

Mephedrone and 3,4-methylenedioxy-methamphetamine: Comparative psychobiological effects as reported by recreational polydrug users.

PubMed

Jones, Lewis; Reed, Phil; Parrott, Andrew

2016-12-01

The purpose of this study was to compare the effects of mephedrone and 3,4-methylenedioxy-methamphetamine (MDMA), as reported by young recreational polydrug users. 152 MDMA users and 81 mephedrone users were recruited through snowballing on social network sites. They completed a standard online questionnaire for either mephedrone or MDMA. The questions covered the average amount taken per session, the longest duration of usage in the last 12-months, subjective effects while on-drug, and recovery effects in the days afterwards. Mephedrone users reported a significantly longer maximum session of use than MDMA users. Mephedrone users also reported a significantly greater average amount used per session. The majority of on-drug subjective ratings did not differ between drugs, with similar increases in entactogenic effects. Although mephedrone users did report significantly more frequent issues with sleeping, anger and anxiety. In relation to recovery, mephedrone users reported more frequent craving, nasal irritation, paranoia, and relationship difficulties. Mephedrone users also rated general recovery effects as more severe over the seven-day period following use, taking more days to feel normal. The acute effects of MDMA and mephedrone were broadly similar. However, the recovery period for mephedrone was more enduring, possibly due to the longer duration of acute session usage. © The Author(s) 2016.

Phisherman v 1.0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Phisherman is an online software tool that was created to help experimenters study phishing. It can potentially be re-purposed to run other human studies. Phisherman enables studies to be run online, so that users can participate from their own computers. This means that experimenters can get data from subjects in their natural settings. Alternatively, an experimenter can also run the app online in a lab-based setting, if that is desired. The software enables the online deployment of a study that is comprised of three main parts: (1) a consent page, (2) a survey, and (3) an identification task, with instruction/transitionmore » screens between each part, allowing the experimenter to provide the user with instructions and messages. Upon logging in, the subject is taken to the permission page, where they agree to or do not agree to take part in the study. If the subject agrees to participate, then the software randomly chooses between doing the survey first (and identification task second) or the identification task first (and survey second). This is to balance possible order effects in the data. Procedurally, in the identification task, the software shows the stimuli to the subject, and asks if she thinks it is a phish (yes/no) and how confident she is about her answer. The subject is given 5 levels of certainty to select from, labeled "low" (1), to "medium" (3), to "high" (5), with the option of picking a level between low and medium (2), and between medium and high (4). After selecting his/her confidence level, then the "Next" button activates, allowing a user to move to the next email. The software saves a given subject's progress in the identification task, so that she may log in and out of the site. The consent page is a space for the experimenter to provide the subject with human studies board /internal review board information, and to formally consent to participate in the study. The survey is a space for the experimenter to provide questions and spaces for the users to input answers (allowing both multiple-choice and free-answer options). Phisherman includes administrative pages for managing the stimuli and users. This includes a tool for the experimenter to create, preview, edit, delete (if desired), and manage stimuli (emails). The stimuli may include pictures (uploaded to an appropriate folder) and links, for realism. The software includes a safety feature that prevents the user from going to any link location or opening a file/image. Instead of re-directing the subject's browser, the software provides a pop-up box with the URL location of where the user would have gone. Another administrative page may be used to create fake subject accounts for testing the software prior to deployment, as well as to delete subject accounts when necessary. Data from the experiment can be downloaded from another administrative page.« less

[Association of indoor air quality with physical health of users in a newly built school building in a university].

PubMed

Mori, Mihoko; Hara, Kunio; Miyakita, Takashi; Ishitake, Tatsuya

2011-01-01

Several users of a newly built school building in a university (new building) complained about their deteriorating physical health. We measured the air quality in the new building, an old school building and atmosphere in September 2007 and February 2008. We also conducted a questionnaire survey of subjective symptoms of users in the new building in February 2008. The university administrator took some remedial actions to improve the indoor air quality after the first measurement. In September 2007, the concentrations of total volatile organic compounds (TVOCs) and 2-ethyl-1-hexanol in the new building were higher than those in the old building and atmosphere. Moreover, the concentrations of TVOCs exceeded the Japanese recommended guideline values. In February 2008, the concentrations of these substances in the new building were lower than the previous values. Out of the 177 users who were surveyed regarding subjective symptoms, 59 responded to the survey. In September 2007, 21 users felt that their physical health had deteriorated, while in February 2008, 12 users felt no deterioration. However, nine users still complained about the deterioration of their physical health. It was suggested that the improvement in the indoor air quality may be influenced by the decrease in room temperature. Even if the concentrations of VOCs are below the recommended guideline values, users with an enhanced sensitivity towards VOCs may lose their tolerance to low-level VOCs. Our findings suggested that a survey of the changes in the subjective symptoms of users should be conducted to evaluate the improvement in the indoor air quality of newly built buildings.

Web Delivery of Interactive Laboratories: Comparison of Three Authoring Tools

NASA Astrophysics Data System (ADS)

Silbar, Richard R.

2002-04-01

It is well-known that the more a student interacts with a subject, the better he or she will learn it. This is particularly true in technical subjects. One way to do this is to have computer-based "laboratories" in which the student manipulates objects on the screen with keyboard or mouse and then sees the outcome of those actions. One example of such a laboratory we have built, using Macromedia's Authorware, deals with addition of two vectors in the geometric approach. The problem with Authorware, however, is that, if one wants to deliver the training over the Web, that requires the download and installation of a big plug-in. Therefore, as an experiment, I built clones of the Vector Addition Laboratory using Macromedia's Director or Flash, each of which have smaller plug-ins which are often already installed in the user's browser. The Director and Flash versions are similar to (but definitely not the same as) the Authorware version. This talk goes into these differences and demonstrates the techniques used. You can view the three examples on-line at http://www.whistlesoft.com/ silbar.

Interlibrary Loan Communications Subsystem: Users Manual.

ERIC Educational Resources Information Center

OCLC Online Computer Library Center, Inc., Dublin, OH.

The OCLC Interlibrary Loan (ILL) Communications Subsystem provides participating libraries with on-line control of ILL transactions. This user manual includes a glossary of terms related to the procedures in using the system. Sections describe computer entry, searching, loan request form, loan response form, ILL procedures, the special message…

The perception of phonological quantity based on durational cues by native speakers, second-language users and nonspeakers of Finnish.

PubMed

Ylinen, Sari; Shestakova, Anna; Alku, Paavo; Huotilainen, Minna

2005-01-01

Some languages, such as Finnish, use speech-sound duration as the primary cue for a phonological quantity distinction. For second-language (L2) learners, quantity is often difficult to master if speech-sound duration plays a less important role in the phonology of their native language (L1). By comparing the categorization performance of native speakers of Finnish, Russian L2 users of Finnish, and non-Finnish-speaking Russians, the present study aimed to determine whether the L2 users, whose native language does not have a quantity distinction, have been able to establish categories for Finnish quantity. The results suggest that the native speakers and some of the L2 users that have been exposed to Finnish for a longer time have access to phonological quantity categories, whereas the L2 users with shorter exposure and the non-Finnish-speaking subjects do not. In addition, by comparing categorization and discrimination tasks it was found that the native speakers show a phoneme-boundary effect for quantity that is cued by duration only, whereas the non-Finnish-speaking subjects and the subjects with low proficiency in Finnish do not.

The influence of non-linear frequency compression on the perception of music by adults with a moderate to sever hearing loss: subjective impressions.

PubMed

Uys, Marinda; Pottas, Lidia; Vinck, Bart; van Dijk, Catherine

2012-12-01

To date, the main direction in frequency-lowering hearing aid studies has been in relation to speech perception abilities. With improvements in hearing aid technology, interest in musical perception as a dimension that could improve hearing aid users' quality of life has grown. The purpose of this study was to determine the influence of non-linear frequency compression (NFC) on hearing aid users' subjective impressions of listening to music. DESIGN & SAMPLE: A survey research design was implemented to elicit participants' (N=40) subjective impressions of musical stimuli with and without NFC. The use of NFC significantly improved hearing aid users' perception of the musical qualities of overall fidelity, tinniness and reverberance. Although participants preferred to listen to the loudness, fullness, crispness, naturalness and pleasantness of music with the use of NFC, these benefits were not significant. The use of NFC can increase hearing aid users' enjoyment and appreciation of music. Given that a relatively large percentage of hearing aid users express a loss of enjoyment of music, audiologists should not ignore the possible benefits of NFC, especially if one takes into account that previous research indicates speech perception benefits with this technology.

The GUI OPAC: Approach with Caution.

ERIC Educational Resources Information Center

Hildreth, Charles R.

1995-01-01

Discusses the graphical user interface (GUI) online public access catalog (OPAC), a user interface that uses images to represent options. Topics include user interface design for information retrieval; designing effective bibliographic displays, including subject headings; two design principles; and what GUIs can bring to OPACs. (LRW)

Do Facebook Status Updates Reflect Subjective Well-Being?

PubMed

Liu, Pan; Tov, William; Kosinski, Michal; Stillwell, David J; Qiu, Lin

2015-07-01

Nowadays, millions of people around the world use social networking sites to express everyday thoughts and feelings. Many researchers have tried to make use of social media to study users' online behaviors and psychological states. However, previous studies show mixed results about whether self-generated contents on Facebook reflect users' subjective well-being (SWB). This study analyzed Facebook status updates to determine the extent to which users' emotional expression predicted their SWB-specifically their self-reported satisfaction with life. It was found that positive emotional expressions on Facebook did not correlate with life satisfaction, whereas negative emotional expressions within the past 9-10 months (but not beyond) were significantly related to life satisfaction. These findings suggest that both the type of emotional expressions and the time frame of status updates determine whether emotional expressions in Facebook status updates can effectively reflect users' SWB. The findings shed light on the characteristics of online social media and improve the understanding of how user-generated contents reflect users' psychological states.

SKYDOSE: A code for gamma skyshine calculations using the integral line-beam method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shultis, J.K.; Faw, R.E.; Brockhoff, R.C.

1994-07-01

SKYDOS evaluates skyshine dose from an isotropic, monoenergetic, point photon source collimated by three simple geometries: (1) a source in a silo; (2) a source behind an infinitely long, vertical, black wall; and (3) a source in a rectangular building. In all three geometries, an optical overhead shield may be specified. The source energy must be between 0.02 and 100 MeV (10 MeV for sources with an overhead shield). This is a user`s manual. Other references give more detail on the integral line-beam method used by SKYDOSE.

Estimating User Influence in Online Social Networks Subject to Information Overload

NASA Astrophysics Data System (ADS)

Li, Pei; Sun, Yunchuan; Chen, Yingwen; Tian, Zhi

2014-11-01

Online social networks have attracted remarkable attention since they provide various approaches for hundreds of millions of people to stay connected with their friends. Due to the existence of information overload, the research on diffusion dynamics in epidemiology cannot be adopted directly to that in online social networks. In this paper, we consider diffusion dynamics in online social networks subject to information overload, and model the information-processing process of a user by a queue with a batch arrival and a finite buffer. We use the average number of times a message is processed after it is generated by a given user to characterize the user influence, which is then estimated through theoretical analysis for a given network. We validate the accuracy of our estimation by simulations, and apply the results to study the impacts of different factors on the user influence. Among the observations, we find that the impact of network size on the user influence is marginal while the user influence decreases with assortativity due to information overload, which is particularly interesting.

Increased self-reported impulsivity in methamphetamine users maintaining drug abstinence.

PubMed

Jones, Hannah W; Dean, Andy C; Price, Kimberly A; London, Edythe D

2016-09-01

Impulsivity has been proposed as an important factor in the initiation and maintenance of addiction. Indirect evidence suggests that some methamphetamine users report less impulsivity when they are using methamphetamine compared to when abstaining from drug use, but this hypothesis has not been directly tested. In this study, self-reports of impulsivity were obtained from 32 methamphetamine-dependent (DSM-IV) research participants and 41 healthy control subjects, using the Barratt Impulsiveness Scale-11. The methamphetamine users were assessed during an active period of methamphetamine use, as determined through urinalysis, and again after approximately 1 week of confirmed abstinence. Control subjects likewise completed two assessments. A subset of participants also completed serial assessments of the Beck Depression Inventory (Methamphetamine Group, N = 17, Control Group, N = 38) and the Methamphetamine Withdrawal Questionnaire (Methamphetamine Group, N = 12). There was a significant interaction of group with time on impulsivity (p = 0.044), reflecting a significant increase from the first to the second assessment in the methamphetamine users (p = 0.013), but no change among healthy control subjects. In contrast, depressive and withdrawal symptoms significantly decreased between the first and second assessments in the methamphetamine users (ps ≤0.01). Change in impulsivity in methamphetamine users was not significantly correlated with change in withdrawal or depression (ps >0.05). These findings suggest that methamphetamine users report more impulsivity when abstaining from drug use, an effect that is not significantly related to methamphetamine withdrawal. Attenuation of impulsivity may reinforce continued methamphetamine use in these individuals.

Subjective evaluation of HEVC in mobile devices

NASA Astrophysics Data System (ADS)

Garcia, Ray; Kalva, Hari

2013-03-01

Mobile compute environments provide a unique set of user needs and expectations that designers must consider. With increased multimedia use in mobile environments, video encoding methods within the smart phone market segment are key factors that contribute to positive user experience. Currently available display resolutions and expected cellular bandwidth are major factors the designer must consider when determining which encoding methods should be supported. The desired goal is to maximize the consumer experience, reduce cost, and reduce time to market. This paper presents a comparative evaluation of the quality of user experience when HEVC and AVC/H.264 video coding standards were used. The goal of the study was to evaluate any improvements in user experience when using HEVC. Subjective comparisons were made between H.264/AVC and HEVC encoding standards in accordance with Doublestimulus impairment scale (DSIS) as defined by ITU-R BT.500-13. Test environments are based on smart phone LCD resolutions and expected cellular bit rates, such as 200kbps and 400kbps. Subjective feedback shows both encoding methods are adequate at 400kbps constant bit rate. However, a noticeable consumer experience gap was observed for 200 kbps. Significantly less H.264 subjective quality is noticed with video sequences that have multiple objects moving and no single point of visual attraction. Video sequences with single points of visual attraction or few moving objects tended to have higher H.264 subjective quality.

Electronic Cigarette Topography in the Natural Environment

PubMed Central

Morabito, P. N.; Roundtree, K. A.

2015-01-01

This paper presents the results of a clinical, observational, descriptive study to quantify the use patterns of electronic cigarette users in their natural environment. Previously published work regarding puff topography has been widely indirect in nature, and qualitative rather than quantitative, with the exception of three studies conducted in a laboratory environment for limited amounts of time. The current study quantifies the variation in puffing behaviors among users as well as the variation for a given user throughout the course of a day. Puff topography characteristics computed for each puffing session by each subject include the number of subject puffs per puffing session, the mean puff duration per session, the mean puff flow rate per session, the mean puff volume per session, and the cumulative puff volume per session. The same puff topography characteristics are computed across all puffing sessions by each single subject and across all subjects in the study cohort. Results indicate significant inter-subject variability with regard to puffing topography, suggesting that a range of representative puffing topography patterns should be used to drive machine-puffed electronic cigarette aerosol evaluation systems. PMID:26053075

Electronic Cigarette Topography in the Natural Environment.

PubMed

Robinson, R J; Hensel, E C; Morabito, P N; Roundtree, K A

2015-01-01

This paper presents the results of a clinical, observational, descriptive study to quantify the use patterns of electronic cigarette users in their natural environment. Previously published work regarding puff topography has been widely indirect in nature, and qualitative rather than quantitative, with the exception of three studies conducted in a laboratory environment for limited amounts of time. The current study quantifies the variation in puffing behaviors among users as well as the variation for a given user throughout the course of a day. Puff topography characteristics computed for each puffing session by each subject include the number of subject puffs per puffing session, the mean puff duration per session, the mean puff flow rate per session, the mean puff volume per session, and the cumulative puff volume per session. The same puff topography characteristics are computed across all puffing sessions by each single subject and across all subjects in the study cohort. Results indicate significant inter-subject variability with regard to puffing topography, suggesting that a range of representative puffing topography patterns should be used to drive machine-puffed electronic cigarette aerosol evaluation systems.

Brain-controlled telepresence robot by motor-disabled people.

PubMed

Tonin, Luca; Carlson, Tom; Leeb, Robert; del R Millán, José

2011-01-01

In this paper we present the first results of users with disabilities in mentally controlling a telepresence robot, a rather complex task as the robot is continuously moving and the user must control it for a long period of time (over 6 minutes) to go along the whole path. These two users drove the telepresence robot from their clinic more than 100 km away. Remarkably, although the patients had never visited the location where the telepresence robot was operating, they achieve similar performances to a group of four healthy users who were familiar with the environment. In particular, the experimental results reported in this paper demonstrate the benefits of shared control for brain-controlled telepresence robots. It allows all subjects (including novel BMI subjects as our users with disabilities) to complete a complex task in similar time and with similar number of commands to those required by manual control.

The design and evaluation of an activity monitoring user interface for people with stroke.

PubMed

Hart, Phil; Bierwirth, Rebekah; Fulk, George; Sazonov, Edward

2014-01-01

Usability is an important topic in the field of telerehabilitation research. Older users with disabilities in particular, present age-related and disability-related challenges that should be accommodated for in the design of a user interface for a telerehabilitation system. This paper describes the design, implementation, and assessment of a telerehabilitation system user interface that tries to maximize usability for an elderly user who has experienced a stroke. An Internet-connected Nintendo(®) Wii™ gaming system is selected as a hardware platform, and a server and website are implemented to process and display the feedback information. The usability of the interface is assessed with a trial consisting of 18 subjects: 10 healthy Doctor of Physical Therapy students and 8 people with a stroke. Results show similar levels of usability and high satisfaction with the gaming system interface from both groups of subjects.

Tagging for Subject Access: A Glimpse into Current Practice by Vendors, Libraries, and Users

ERIC Educational Resources Information Center

Yang, Sharon Q.

2012-01-01

The study looked into the 307 Koha libraries listed in Breeding's Library Technology Guides. Since all the tag clouds in Koha are user-contributed, their adoption and usage can shed light on the extent to which libraries are supporting user tagging. The research also revealed that public library users are more actively involved in tagging than…

Tools for Integrating Data Access from the IRIS DMC into Research Workflows

NASA Astrophysics Data System (ADS)

Reyes, C. G.; Suleiman, Y. Y.; Trabant, C.; Karstens, R.; Weertman, B. R.

2012-12-01

Web service interfaces at the IRIS Data Management Center (DMC) provide access to a vast archive of seismological and related geophysical data. These interfaces are designed to easily incorporate data access into data processing workflows. Examples of data that may be accessed include: time series data, related metadata, and earthquake information. The DMC has developed command line scripts, MATLAB® interfaces and a Java library to support a wide variety of data access needs. Users of these interfaces do not need to concern themselves with web service details, networking, or even (in most cases) data conversion. Fetch scripts allow access to the DMC archive and are a comfortable fit for command line users. These scripts are written in Perl and are well suited for automation and integration into existing workflows on most operating systems. For metdata and event information, the Fetch scripts even parse the returned data into simple text summaries. The IRIS Java Web Services Library (IRIS-WS Library) allows Java developers the ability to create programs that access the DMC archives seamlessly. By returning the data and information as native Java objects the Library insulates the developer from data formats, network programming and web service details. The MATLAB interfaces leverage this library to allow users access to the DMC archive directly from within MATLAB (r2009b or newer), returning data into variables for immediate use. Data users and research groups are developing other toolkits that use the DMC's web services. Notably, the ObsPy framework developed at LMU Munich is a Python Toolbox that allows seamless access to data and information via the DMC services. Another example is the MATLAB-based GISMO and Waveform Suite developments that can now access data via web services. In summary, there now exist a host of ways that researchers can bring IRIS DMC data directly into their workflows. MATLAB users can use irisFetch.m, command line users can use the various Fetch scripts, Java users can use the IRIS-WS library, and Python users may request data through ObsPy. To learn more about any of these clients see http://www.iris.edu/ws/wsclients/.

Auditory cortical activity during cochlear implant-mediated perception of spoken language, melody, and rhythm.

PubMed

Limb, Charles J; Molloy, Anne T; Jiradejvong, Patpong; Braun, Allen R

2010-03-01

Despite the significant advances in language perception for cochlear implant (CI) recipients, music perception continues to be a major challenge for implant-mediated listening. Our understanding of the neural mechanisms that underlie successful implant listening remains limited. To our knowledge, this study represents the first neuroimaging investigation of music perception in CI users, with the hypothesis that CI subjects would demonstrate greater auditory cortical activation than normal hearing controls. H(2) (15)O positron emission tomography (PET) was used here to assess auditory cortical activation patterns in ten postlingually deafened CI patients and ten normal hearing control subjects. Subjects were presented with language, melody, and rhythm tasks during scanning. Our results show significant auditory cortical activation in implant subjects in comparison to control subjects for language, melody, and rhythm. The greatest activity in CI users compared to controls was seen for language tasks, which is thought to reflect both implant and neural specializations for language processing. For musical stimuli, PET scanning revealed significantly greater activation during rhythm perception in CI subjects (compared to control subjects), and the least activation during melody perception, which was the most difficult task for CI users. These results may suggest a possible relationship between auditory performance and degree of auditory cortical activation in implant recipients that deserves further study.

Safeguarding End-User Military Software

DTIC Science & Technology

2014-12-04

product lines using composi- tional symbolic execution [17] Software product lines are families of products defined by feature commonality and vari...ability, with a well-managed asset base. Recent work in testing of software product lines has exploited similarities across development phases to reuse...feature dependence graph to extract the set of possible interaction trees in a product family. It composes these to incrementally and symbolically

Cortical and subcortical mechanisms of brain-machine interfaces.

PubMed

Marchesotti, Silvia; Martuzzi, Roberto; Schurger, Aaron; Blefari, Maria Laura; Del Millán, José R; Bleuler, Hannes; Blanke, Olaf

2017-06-01

Technical advances in the field of Brain-Machine Interfaces (BMIs) enable users to control a variety of external devices such as robotic arms, wheelchairs, virtual entities and communication systems through the decoding of brain signals in real time. Most BMI systems sample activity from restricted brain regions, typically the motor and premotor cortex, with limited spatial resolution. Despite the growing number of applications, the cortical and subcortical systems involved in BMI control are currently unknown at the whole-brain level. Here, we provide a comprehensive and detailed report of the areas active during on-line BMI control. We recorded functional magnetic resonance imaging (fMRI) data while participants controlled an EEG-based BMI inside the scanner. We identified the regions activated during BMI control and how they overlap with those involved in motor imagery (without any BMI control). In addition, we investigated which regions reflect the subjective sense of controlling a BMI, the sense of agency for BMI-actions. Our data revealed an extended cortical-subcortical network involved in operating a motor-imagery BMI. This includes not only sensorimotor regions but also the posterior parietal cortex, the insula and the lateral occipital cortex. Interestingly, the basal ganglia and the anterior cingulate cortex were involved in the subjective sense of controlling the BMI. These results inform basic neuroscience by showing that the mechanisms of BMI control extend beyond sensorimotor cortices. This knowledge may be useful for the development of BMIs that offer a more natural and embodied feeling of control for the user. Hum Brain Mapp 38:2971-2989, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

A semi-automatic framework of measuring pulmonary arterial metrics at anatomic airway locations using CT imaging

NASA Astrophysics Data System (ADS)

Jin, Dakai; Guo, Junfeng; Dougherty, Timothy M.; Iyer, Krishna S.; Hoffman, Eric A.; Saha, Punam K.

2016-03-01

Pulmonary vascular dysfunction has been implicated in smoking-related susceptibility to emphysema. With the growing interest in characterizing arterial morphology for early evaluation of the vascular role in pulmonary diseases, there is an increasing need for the standardization of a framework for arterial morphological assessment at airway segmental levels. In this paper, we present an effective and robust semi-automatic framework to segment pulmonary arteries at different anatomic airway branches and measure their cross-sectional area (CSA). The method starts with user-specified endpoints of a target arterial segment through a custom-built graphical user interface. It then automatically detect the centerline joining the endpoints, determines the local structure orientation and computes the CSA along the centerline after filtering out the adjacent pulmonary structures, such as veins or airway walls. Several new techniques are presented, including collision-impact based cost function for centerline detection, radial sample-line based CSA computation, and outlier analysis of radial distance to subtract adjacent neighboring structures in the CSA measurement. The method was applied to repeat-scan pulmonary multirow detector CT (MDCT) images from ten healthy subjects (age: 21-48 Yrs, mean: 28.5 Yrs; 7 female) at functional residual capacity (FRC). The reproducibility of computed arterial CSA from four airway segmental regions in middle and lower lobes was analyzed. The overall repeat-scan intra-class correlation (ICC) of the computed CSA from all four airway regions in ten subjects was 96% with maximum ICC found at LB10 and RB4 regions.

EMPIRICAL STUDY ON USABILITY OF CROSSING SUPPORT SYSTEM FOR VISUALLY DISABLED AT SIGNALIZED INTERSECTION

NASA Astrophysics Data System (ADS)

Suzuki, Koji; Fujita, Motohiro; Matsuura, Kazuma; Fukuzono, Kazuyuki

This paper evaluates the adjustment process for crossing support system for visually disabled at signalized intersections with the use of pedestrian traffic signals in concert with visible light communication (VLC) technology through outdoor experiments. As for the experiments, we put a blindfold on sighted people by eye mask in order to analyze the behavior of acquired visually disabled. And we used a full-scale crosswalk which is taking into consideration the crossing slope, the bumps at the edge of a crosswalk between the roadway and the sidewalkand crosswalk line. From the results of the survey, it is found that repetitive use of the VLC system decreased the number of lost their bearings completely and ended up standing immobile and reduced the crossing time for each person. On the other hand, it is shown that the performance of our VLC system is nearly equal to the existing support system from the view point of crossing time and the number of standing immobile and we clarified the effect factor for guidance accuracy by the regression analyses. Then we broke test subjects down into patterns by cluster analysis, and explained the walking characteristics for each group as they used the VLC system. In addition, we conducted the additional surveys for the quasi-blind subjects who had difficulty walking by using VLC system and visually impaired users. As a result, it is revealed that guidance accuracy was improved by providing the information about their receiving movement at several points on crosswalk and the habit of their walks for each user.

A New Skin Tensiometer Device: Computational Analyses To Understand Biodynamic Excisional Skin Tension Lines.

PubMed

Paul, Sharad P; Matulich, Justin; Charlton, Nick

2016-07-25

One of the problems in planning cutaneous surgery is that human skin is anisotropic, or directionally dependent. Indeed, skin tension varies between individuals and at different body sites. Many a surgeon has tried to design different devices to measure skin tension to help plan excisional surgery, or to understand wound healing. However, many of the devices have been beset with problems due to many confounding variables - differences in technical ability, material (sutures) used and variability between different users. We describe the development of a new skin tensiometer that overcomes many historical technical issues. A new skin tension measuring device is presented here. It was designed to be less user-dependent, more reliable and usable on different bodily sites. The design and computational optimizations are discussed. Our skin tensiometer has helped understand the differences between incisional and excisional skin lines. Langer, who pioneered the concept of skin tension lines, created incisional lines that differ from lines caused by forces that need to be overcome when large wounds are closed surgically (excisional tension). The use of this innovative device has led to understanding of skin biomechanics and best excisional skin tension (BEST) lines.

A New Skin Tensiometer Device: Computational Analyses To Understand Biodynamic Excisional Skin Tension Lines

PubMed Central

Paul, Sharad P.; Matulich, Justin; Charlton, Nick

2016-01-01

One of the problems in planning cutaneous surgery is that human skin is anisotropic, or directionally dependent. Indeed, skin tension varies between individuals and at different body sites. Many a surgeon has tried to design different devices to measure skin tension to help plan excisional surgery, or to understand wound healing. However, many of the devices have been beset with problems due to many confounding variables - differences in technical ability, material (sutures) used and variability between different users. We describe the development of a new skin tensiometer that overcomes many historical technical issues. A new skin tension measuring device is presented here. It was designed to be less user-dependent, more reliable and usable on different bodily sites. The design and computational optimizations are discussed. Our skin tensiometer has helped understand the differences between incisional and excisional skin lines. Langer, who pioneered the concept of skin tension lines, created incisional lines that differ from lines caused by forces that need to be overcome when large wounds are closed surgically (excisional tension). The use of this innovative device has led to understanding of skin biomechanics and best excisional skin tension (BEST) lines. PMID:27453542

Charging Users for Library Service.

ERIC Educational Resources Information Center

Cooper, Michael D.

1978-01-01

Examines the question of instituting direct charges for library service, using on-line bibliographic searching as an example, and contrasts this with the current indirect charging system where services are paid for by taxes. Information, as a merit good, should be supplied with or without direct charges, depending upon user status. (CWM)

POLO: a user's guide to Probit Or LOgit analysis.

Treesearch

Jacqueline L. Robertson; Robert M. Russell; N.E. Savin

1980-01-01

This user's guide provides detailed instructions for the use of POLO (Probit Or LOgit), a computer program for the analysis of quantal response data such as that obtained from insecticide bioassays by the techniques of probit or logit analysis. Dosage-response lines may be compared for parallelism or...

Encounters with the OPAC: On-Line Searching in Public Libraries.

ERIC Educational Resources Information Center

Slone, Deborah J.

2000-01-01

Reports on a qualitative study that explored strategies and behaviors of public library users during interaction with an online public access catalog, and users' confidence in finding needed information online. Discusses results of questionnaires, interviews, and observations that examined unknown-item searches, area searches, and known-item…

Meaningful Real-Time Graphics Workstation Performance Measurements

DTIC Science & Technology

1988-11-01

alike can effectively operate the program with little or no help from user’s manuals or other users. A thorough and efficient design of command line...Specifica- tions, San Jose, California, 1988. 4. Apgar , Brian, Bersack, Bret and Mammen, Abraham, "A Display System for the Stellarr m Graphics

Transcending Library Catalogs: A Comparative Study of Controlled Terms in Library of Congress Subject Headings and User-Generated Tags in LibraryThing for Transgender Books

ERIC Educational Resources Information Center

Adler, Melissa

2009-01-01

Perhaps the greatest power of folksonomies, especially when set against controlled vocabularies like the Library of Congress Subject Headings, lies in their capacity to empower user communities to name their own resources in their own terms. This article analyzes the potential and limitations of both folksonomies and controlled vocabularies for…

The SUNY biomedical communication network: six years of progress in on-line bibiographic retrieval.

PubMed Central

Egeland, J

1975-01-01

The SUNY Biomedical Communication Network became operational in 1968 as the first on-line bibliograhpic retrieval service for biomedical literature. Since 1968, the SUNY/BCN has grown in size from nine to thirty-two medical and university libraries and has expanded its data base coverage to include the ERIC and Psychological Abstracts data bases in addition to the full ten-year retrospective MEDLARS data base. Aside from the continuous provision of an on-line searching system, the SUNY experience over the last six years has yielded valuable information in the following areas of: (1) monograph indexing and retrieval, (2) shared cataloging, (3) user interaction and education in on-line systems, and (4) member participation in Network policy-making processes. The continued success of the SUNY/BCN is evidence that it is possible to provide a high quality on-line bibliographic retrieval system at cost to academic institutions. SUNY's success in this effort is the result of centralized resource sharing and effective regional networking, combined with thoughtful planning by user advisory committees. PMID:1173557

Depressive symptoms and web user experience

PubMed Central

Thielsch, Carolin

2018-01-01

Background Depression, as one of the most prevalent mental disorders, is expected to become a leading cause of disability. While evidence-based treatments are not always easily accessible, Internet-based information and self-help appears as a promising approach to improve the strained supply situation by avoiding barriers of traditional offline treatment. User experience in the domain of mental problems therefore emerges as an important research topic. The aim of our study is to investigate the impact of depressive symptoms on subjective and objective measures of web user experience. Method In this two-part online study (Ntotal = 721) we investigate the relationship between depressive symptoms of web users and basic website characteristics (i.e., content, subjective and objective usability, aesthetics). Participants completed search and memory tasks on different fully-functional websites. In addition, they were asked to evaluate the given websites with standardized measures and were screened for symptoms of depression using the PHQ-9. We used structural equation modeling (SEM) to determine whether depression severity affects users’ perception of and performance in using information websites. Results We found significant associations between depressive symptoms and subjective user experience, specifically of website content, usability, and aesthetics, as well as an effect of content perception on the overall appraisal of a website in terms of the intention to visit it again. Small yet significant negative effects of depression severity on all named subjective website evaluations were revealed, leading to an indirect negative effect on the intention to revisit a website via impaired content perceptions. However, objective task performance was not influenced by depressiveness of users. Discussion Depression emerges as capable of altering the subjective perception of a website to some extend with respect to the main features content, usability, and aesthetics. The user experience of a website is crucial, especially as it facilitates revisiting a website and thus might be relevant in avoiding drop-out in online interventions. Thus, the biased impression of persons affected by symptoms of depression and resulting needs of those users should be considered when designing and evaluating E-(Mental)-Health-platforms. The high prevalence of some mental disorders such as depression in the general population stresses the need for further investigations of the found effects. PMID:29507832

Methamphetamine-related psychiatric symptoms and reduced brain dopamine transporters studied with PET.

PubMed

Sekine, Y; Iyo, M; Ouchi, Y; Matsunaga, T; Tsukada, H; Okada, H; Yoshikawa, E; Futatsubashi, M; Takei, N; Mori, N

2001-08-01

A positron emission tomography (PET) study has suggested that dopamine transporter density of the caudate/putamen is reduced in methamphetamine users. The authors measured nucleus accumbens and prefrontal cortex density, in addition to caudate/putamen density, in methamphetamine users and assessed the relation of these measures to the subjects' clinical characteristics. PET and 2-beta-carbomethoxy-3beta-(4-[(11)C] fluorophenyl)tropane, a dopamine transporter ligand, were used to measure dopamine transporter density in 11 male methamphetamine users and nine male comparison subjects who did not use methamphetamine. Psychiatric symptoms in methamphetamine users were evaluated by using the Brief Psychiatric Rating Scale and applying a craving score. The dopamine transporter density in all three of the regions observed was significantly lower in the methamphetamine users than the comparison subjects. The severity of psychiatric symptoms was significantly correlated with the duration of methamphetamine use. The dopamine transporter reduction in the caudate/putamen and nucleus accumbens was significantly associated with the duration of methamphetamine use and closely related to the severity of persistent psychiatric symptoms. These findings suggest that longer use of methamphetamine may cause more severe psychiatric symptoms and greater reduction of dopamine transporter density in the brain. They also show that the dopamine transporter reduction may be long-lasting, even if methamphetamine use ceases. Further, persistent psychiatric symptoms in methamphetamine users, including psychotic symptoms, may be attributable to the reduction of dopamine transporter density.

Interactive team suggestion for users of digital libraries: Using subject thesauri and co-occurrence lists for information retrieval

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schatz, B.R.; Johnson, E.H.; Cochrane, P.A.

The basic problem in information retrieval is that large-scale searches can only match terms specified by the user to terms appearing in documents in the digital library collection. Intermediate sources that support term suggestion can thus enhance retrieval by providing alternative search terms for the user. Term suggestion increases the recall, while interaction enables the user to attempt to not decrease the precision. We are building a prototype user interface that will become the Web interface for the University of Illinois Digital Library Initiative (DLI) testbed. It supports the principal of multiple views, where different kinds of term suggestors canmore » be used to complement search and each other. This paper discusses its operation with two complementary term suggestors, subject thesauri and co-occurrence lists, and compared their utility. Thesauri are generated by human indexers and place selected terms in a subject hierarchy. Co-occurrence lists are generated by computer and place all terms in frequency order of occurrence together. This paper concludes with a discussion of how multiple views can help provide good quality Search for the Net. This is a paper about the design of a retrieval system prototype that allows users to simultaneously combine terms offered by different suggestion techniques, not about comparing the merits of each in a systematic and controlled way. It offers no experimental results.« less

The roles of 'subjective computer training' and management support in the use of computers in community health centres.

PubMed

Yaghmaie, Farideh; Jayasuriya, Rohan

2004-01-01

There have been many changes made to information systems in the last decade. Changes in information systems require users constantly to update their computer knowledge and skills. Computer training is a critical issue for any user because it offers them considerable new skills. The purpose of this study was to measure the effects of 'subjective computer training' and management support on attitudes to computers, computer anxiety and subjective norms to use computers. The data were collected from community health centre staff. The results of the study showed that health staff trained in computer use had more favourable attitudes to computers, less computer anxiety and more awareness of others' expectations about computer use than untrained users. However, there was no relationship between management support and computer attitude, computer anxiety or subjective norms. Lack of computer training for the majority of healthcare staff confirmed the need for more attention to this issue, particularly in health centres.

Effect of Anti-Tobacco Audiovisual Messages on Knowledge and Attitude towards Tobacco Use in North India.

PubMed

Kaur, Jagdish; Kishore, Jugal; Kumar, Monika

2012-10-01

Tobacco use is one of the leading preventable causes of death globally. Mass media plays a significant role in initiation as well as in control of tobacco use. To assess the effect of viewing anti-tobacco audiovisual messages on knowledge and attitudinal change towards tobacco use. Interventional community-based study. A total of 1999 cinema attendees (age 10 years and above), irrespective of their smoking or tobacco using status, were selected from four cinema halls (two urban, one semi-urban, and one rural site). In pre-exposure phase 1000 subjects and in post-exposure phase 999 subjects were interviewed using a pre-tested questionnaire. After collecting baseline information, the other days were chosen for screening the audiovisual spots that were shown twice per show. After the show, subjects were interviewed to assess its effect. Proportions of two independent groups were compared and statistically significance using chi-square test was accepted if error was less than 0.05%. Overall 784 (39.2%) subjects were tobacco users, 52.6% were non-tobacco users and 8.2% were former tobacco users. Important factors for initiation of tobacco use were peer pressure (62%), imitating elders (53.4%) and imitating celebrity (63.5%). Tobacco users were significantly less likely than non-tobacco users to recall watching the spots during movie (72.1% vs. 79.1%). Anti-tobacco advertisement gave inspiration to 37% of subjects not to use tobacco. The celebrity in advertisement influenced the people's attention. There was significant improvement in knowledge and attitudes towards anti-tobacco legal and public health measures in post exposure group. The anti-tobacco advertisements have been found to be effective in enhancing knowledge as well as in transforming to positive attitude of the people about tobacco use.

Gender and Age Effects on the Trajectory of Depression in Opioid Users during Methadone Maintenance Treatment.

PubMed

Wang, Peng-Wei; Lin, Huang-Chi; Yang, Yi-Hsin Connie; Hsu, Chih-Yao; Chung, Kuan-Sheng; Wu, Hung-Chi; Yen, Cheng-Fang

2017-01-01

Both heroin use and depression are significant health problems. Methadone maintenance treatment (MMT) can be of great benefit to heroin users. However, changes in the level of depression in heroin users during MMT are not clear. Gender and age are also important factors in the development of depression, and whether gender and age moderate changes in depression in heroin users during MMT warrants further study. This study aimed to explore: (1) the trajectory of depression in opioid users during MMT and (2) the moderating effects of gender and age on the trajectory of depression in opioid users receiving MMT. A total of 294 intravenous heroin users were recruited into this 9-month observational study. The level of depression was measured at the intake interview and at follow-up interviews every 3 months. A latent growth model was used to analyze the trajectory of the level of depression among the participants. Depression improved rapidly during the first 3 months of MMT and slowly after the first 3 months in both the female and male heroin users. There was no gender difference in the level of depression at each follow-up point. The level of depression in the female heroin users decreased faster than that in the male heroin users. In addition, the level of depression in the younger heroin users decreased faster than that in the older subjects. Depression in female and younger heroin users improved more rapidly than in male and older subjects, respectively.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davida, G.I.; Frankel, Y.; Matt, B.J.

In developing secure applications and systems, the designers often must incorporate secure user identification in the design specification. In this paper, the authors study secure off line authenticated user identification schemes based on a biometric system that can measure a user`s biometric accurately (up to some Hamming distance). The schemes presented here enhance identification and authorization in secure applications by binding a biometric template with authorization information on a token such as a magnetic strip. Also developed here are schemes specifically designed to minimize the compromise of a user`s private biometrics data, encapsulated in the authorization information, without requiring securemore » hardware tokens. In this paper the authors furthermore study the feasibility of biometrics performing as an enabling technology for secure system and application design. The authors investigate a new technology which allows a user`s biometrics to facilitate cryptographic mechanisms.« less

A high prevalence of abnormal personality traits in chronic users of anabolic-androgenic steroids.

PubMed Central

Cooper, C J; Noakes, T D; Dunne, T; Lambert, M I; Rochford, K

1996-01-01

OBJECTIVE: (1) To assess the personality profiles of the anabolic androgenic steroid users (AAS) and (2) to determine whether valid premorbid personality traits could be obtained from cross sectional assessment using multisource data. METHODS: The first author became a participant-observer in a group of body builders. An experimental group of body builders who had been using AAS for no more than 18 months (n = 12) was identified. A group of control subjects, each of whom claimed that he did not, and never had, used AAS (n = 12) was also recruited during this period. Key informants played a crucial role in recruiting subjects representative of the AAS and body building communities. An interview schedule based on the Diagnostic and statistical manual of mental disorders (DSM3-R) personality disorder criteria was conducted with each subject. Additional data were obtained from an AAS using informant and significant others including family and friends. RESULTS: The user group was significantly heavier than the control group and showed abnormal personality traits, in contrast to the control group. Personality traits of AAS users before the onset of AAS use, assessed retrospectively, were not different from personality traits of control subjects. There were significant differences between the before and after personality traits in AAS user group. CONCLUSIONS: The results suggest (1) that AAS use is associated with significant disturbances in personality profile, and (2) that these personality disturbances are possibly the direct result of AAS use. PMID:8889121

A high prevalence of abnormal personality traits in chronic users of anabolic-androgenic steroids.

PubMed

Cooper, C J; Noakes, T D; Dunne, T; Lambert, M I; Rochford, K

1996-09-01

(1) To assess the personality profiles of the anabolic androgenic steroid users (AAS) and (2) to determine whether valid premorbid personality traits could be obtained from cross sectional assessment using multisource data. The first author became a participant-observer in a group of body builders. An experimental group of body builders who had been using AAS for no more than 18 months (n = 12) was identified. A group of control subjects, each of whom claimed that he did not, and never had, used AAS (n = 12) was also recruited during this period. Key informants played a crucial role in recruiting subjects representative of the AAS and body building communities. An interview schedule based on the Diagnostic and statistical manual of mental disorders (DSM3-R) personality disorder criteria was conducted with each subject. Additional data were obtained from an AAS using informant and significant others including family and friends. The user group was significantly heavier than the control group and showed abnormal personality traits, in contrast to the control group. Personality traits of AAS users before the onset of AAS use, assessed retrospectively, were not different from personality traits of control subjects. There were significant differences between the before and after personality traits in AAS user group. The results suggest (1) that AAS use is associated with significant disturbances in personality profile, and (2) that these personality disturbances are possibly the direct result of AAS use.

Recent Upgrades at the Fermilab Test Beam Facility

NASA Astrophysics Data System (ADS)

Rominsky, Mandy

2016-03-01

The Fermilab Test Beam Facility is a world class facility for testing and characterizing particle detectors. The facility has been in operation since 2005 and has undergone significant upgrades in the last two years. A second beam line with cryogenic support has been added and the facility has adopted the MIDAS data acquisition system. The facility also recently added a cosmic telescope test stand and improved tracking capabilities. With two operational beam lines, the facility can deliver a variety of particle types and momenta ranging from 120 GeV protons in the primary beam line down to 200 MeV particles in the tertiary beam line. In addition, recent work has focused on analyzing the beam structure to provide users with information on the data they are collecting. With these improvements, the Fermilab Test Beam facility is capable of supporting High Energy physics applications as well as industry users. The upgrades will be discussed along with plans for future improvements.

Older users, multimodal reminders and assisted living technology.

PubMed

Warnock, David; McGee-Lennon, Marilyn; Brewster, Stephen

2012-09-01

The primary users of assisted living technology are older people who are likely to have one or more sensory impairments. Multimodal technology allows users to interact via non-impaired senses and provides alternative ways to interact if primary interaction methods fail. An empirical user study was carried out with older participants which evaluated the performance, disruptiveness and subjective workload of visual, audio, tactile and olfactory notifications then compared the results with earlier findings in younger participants. It was found that disruption and subjective workload were not affected by modality, although some modalities were more effective at delivering information accurately. It is concluded that although further studies need to be carried out in a real-world settings, the findings support the argument for multiple modalities in assisted living technology.

Multidimensional scaling of ideological landscape on social network sites

NASA Astrophysics Data System (ADS)

Lee, Deokjae; Hahn, Kyu S.; Park, Juyong

2012-02-01

Social network sites (SNSs) are valuable source of information on various subjects in network science. Recently, political activity of SNSs users has increasing attention and is an interesting interdisciplinary subject of physical and social science. In this work, we measure ideological positions of the legislators of U.S. and South Korea (S.K.) evaluated by Twitter users, using the information employed in the bipartite network structure of the legislators and their Twitter followers. We compare the result with ideological positions constructed from roll call record of the legislators. This shows there is a discrepancy between the ideological positions evaluated by Twitter users and actual positions estimated from roll call votes in S.K. We also asses the ideological positions of the Twitter users themselves and analyze the distribution of the positions.

Real-Time Multimission Event Notification System for Mars Relay

NASA Technical Reports Server (NTRS)

Wallick, Michael N.; Allard, Daniel A.; Gladden, Roy E.; Wang, Paul; Hy, Franklin H.

2013-01-01

As the Mars Relay Network is in constant flux (missions and teams going through their daily workflow), it is imperative that users are aware of such state changes. For example, a change by an orbiter team can affect operations on a lander team. This software provides an ambient view of the real-time status of the Mars network. The Mars Relay Operations Service (MaROS) comprises a number of tools to coordinate, plan, and visualize various aspects of the Mars Relay Network. As part of MaROS, a feature set was developed that operates on several levels of the software architecture. These levels include a Web-based user interface, a back-end "ReSTlet" built in Java, and databases that store the data as it is received from the network. The result is a real-time event notification and management system, so mission teams can track and act upon events on a moment-by-moment basis. This software retrieves events from MaROS and displays them to the end user. Updates happen in real time, i.e., messages are pushed to the user while logged into the system, and queued when the user is not online for later viewing. The software does not do away with the email notifications, but augments them with in-line notifications. Further, this software expands the events that can generate a notification, and allows user-generated notifications. Existing software sends a smaller subset of mission-generated notifications via email. A common complaint of users was that the system-generated e-mails often "get lost" with other e-mail that comes in. This software allows for an expanded set (including user-generated) of notifications displayed in-line of the program. By separating notifications, this can improve a user's workflow.

Language workbench user interfaces for data analysis

PubMed Central

Benson, Victoria M.

2015-01-01

Biological data analysis is frequently performed with command line software. While this practice provides considerable flexibility for computationally savy individuals, such as investigators trained in bioinformatics, this also creates a barrier to the widespread use of data analysis software by investigators trained as biologists and/or clinicians. Workflow systems such as Galaxy and Taverna have been developed to try and provide generic user interfaces that can wrap command line analysis software. These solutions are useful for problems that can be solved with workflows, and that do not require specialized user interfaces. However, some types of analyses can benefit from custom user interfaces. For instance, developing biomarker models from high-throughput data is a type of analysis that can be expressed more succinctly with specialized user interfaces. Here, we show how Language Workbench (LW) technology can be used to model the biomarker development and validation process. We developed a language that models the concepts of Dataset, Endpoint, Feature Selection Method and Classifier. These high-level language concepts map directly to abstractions that analysts who develop biomarker models are familiar with. We found that user interfaces developed in the Meta-Programming System (MPS) LW provide convenient means to configure a biomarker development project, to train models and view the validation statistics. We discuss several advantages of developing user interfaces for data analysis with a LW, including increased interface consistency, portability and extension by language composition. The language developed during this experiment is distributed as an MPS plugin (available at http://campagnelab.org/software/bdval-for-mps/). PMID:25755929

Preliminary results of an examination of electronic cigarette user puff topography: the effect of a mouthpiece-based topography measurement device on plasma nicotine and subjective effects.

PubMed

Spindle, Tory R; Breland, Alison B; Karaoghlanian, Nareg V; Shihadeh, Alan L; Eissenberg, Thomas

2015-02-01

Electronic cigarettes (ECIGs) heat a nicotine-containing solution; the resulting aerosol is inhaled by the user. Nicotine delivery may be affected by users' puffing behavior (puff topography), and little is known about the puff topography of ECIG users. Puff topography can be measured using mouthpiece-based computerized systems. However, the extent to which a mouthpiece influences nicotine delivery and subjective effects in ECIG users is unknown. Plasma nicotine concentration, heart rate, and subjective effects were measured in 13 experienced ECIG users who used their preferred ECIG and liquid (≥ 12 mg/ml nicotine) during 2 sessions (with or without a mouthpiece). In both sessions, participants completed an ECIG use session in which they were instructed to take 10 puffs with 30-second inter-puff intervals. Puff topography was recorded in the mouthpiece condition. Almost all measures of the effects of ECIG use were independent of topography measurement. Collapsed across session, mean plasma nicotine concentration increased by 16.8 ng/ml, and mean heart rate increased by 8.5 bpm (ps < .05). Withdrawal symptoms decreased significantly after ECIG use. Participants reported that the mouthpiece affected awareness and made ECIG use more difficult. Relative to previously reported data for tobacco cigarette smokers using similar topography measurement equipment, ECIG-using participants took larger and longer puffs with lower flow rates. In experienced ECIG users, measuring ECIG topography did not influence ECIG-associated nicotine delivery or most measures of withdrawal suppression. Topography measurement systems will need to account for the low flow rates observed for ECIG users. © The Author 2014. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

MDMA ("Ecstasy") and its association with cerebrovascular accidents: preliminary findings.

PubMed

Reneman, L; Habraken, J B; Majoie, C B; Booij, J; den Heeten, G J

2000-01-01

Abuse of the popular recreational drug "Ecstasy" (MDMA) has been linked to the occurrence of cerebrovascular accidents. It is known that MDMA alters brain serotonin (5-HT) concentrations and that brain postsynaptic 5-HT(2) receptors play a role in the regulation of brain microvasculature. Therefore, we used brain imaging to find out whether MDMA use predisposes one to cerebrovascular accidents by altering brain 5-HT neurotransmission. The effects of MDMA use on brain cortical 5-HT(2A) receptor densities were studied using [(123)I]R91150 single-photon emission CT in 10 abstinent recent MDMA users, five former MDMA users, and 10 healthy control subjects. Furthermore, to examine whether changes in brain 5-HT(2A) receptor densities are associated with alterations in blood vessel volumes, we calculated relative cerebral blood volume maps from dynamic MR imaging sets in five MDMA users and six healthy control subjects. An analysis of variance revealed that mean cortical [(123)I]R91150 binding ratios were significantly lower in recent MDMA users than in former MDMA users and control subjects. This finding suggests down-regulation of 5-HT(2) receptors caused by MDMA-induced 5-HT release. Furthermore, in MDMA users, low cortical 5-HT(2) receptor densities were significantly associated with low cerebral blood vessel volumes (implicating vasoconstriction) and high cortical 5-HT(2) receptor densities with high cerebral blood vessel volumes (implicating vasodilatation) in specific brain regions. These findings suggest a relationship between the serotonergic system and an altered regulation of 5-HT(2) receptors in human MDMA users. MDMA users may therefore be at risk for cerebrovascular accidents resulting from alterations in the 5-HT neurotransmission system.

Interaction Between Functional Genetic Variation of DRD2 and Cannabis Use on Risk of Psychosis

PubMed Central

Colizzi, Marco; Iyegbe, Conrad; Powell, John; Ursini, Gianluca; Porcelli, Annamaria; Bonvino, Aurora; Taurisano, Paolo; Romano, Raffaella; Masellis, Rita; Blasi, Giuseppe; Morgan, Craig; Aitchison, Katherine; Mondelli, Valeria; Luzi, Sonija; Kolliakou, Anna; David, Anthony; Murray, Robin M.; Bertolino, Alessandro; Forti, Marta Di

2015-01-01

Both cannabis use and the dopamine receptor (DRD2) gene have been associated with schizophrenia, psychosis-like experiences, and cognition. However, there are no published data investigating whether genetically determined variation in DRD2 dopaminergic signaling might play a role in individual susceptibility to cannabis-associated psychosis. We genotyped (1) a case-control study of 272 patients with their first episode of psychosis and 234 controls, and also from (2) a sample of 252 healthy subjects, for functional variation in DRD2, rs1076560. Data on history of cannabis use were collected on all the studied subjects by administering the Cannabis Experience Questionnaire. In the healthy subjects’ sample, we also collected data on schizotypy and cognitive performance using the Schizotypal Personality Questionnaire and the N-back working memory task. In the case-control study, we found a significant interaction between the rs1076560 DRD2 genotype and cannabis use in influencing the likelihood of a psychotic disorder. Among cannabis users, carriers of the DRD2, rs1076560, T allele showed a 3-fold increased probability to suffer a psychotic disorder compared with GG carriers (OR = 3.07; 95% confidence interval [CI]: 1.22–7.63). Among daily users, T carrying subjects showed a 5-fold increase in the odds of psychosis compared to GG carriers (OR = 4.82; 95% CI: 1.39–16.71). Among the healthy subjects, T carrying cannabis users had increased schizotypy compared with T carrying cannabis-naïve subjects, GG cannabis users, and GG cannabis-naïve subjects (all P ≤ .025). T carrying cannabis users had reduced working memory accuracy compared with the other groups (all P ≤ .008). Thus, variation of the DRD2, rs1076560, genotype may modulate the psychosis-inducing effect of cannabis use. PMID:25829376

Failure to initiate early insulin therapy - A risk factor for diabetic retinopathy in insulin users with Type 2 diabetes mellitus: Sankara Nethralaya-Diabetic Retinopathy Epidemiology and Molecular Genetics Study (SN-DREAMS, Report number 35).

PubMed

Gupta, Aditi; Delhiwala, Kushal S; Raman, Rajiv P G; Sharma, Tarun; Srinivasan, Sangeetha; Kulothungan, Vaitheeswaran

2016-06-01

Insulin users have been reported to have a higher incidence of diabetic retinopathy (DR). The aim was to elucidate the factors associated with DR among insulin users, especially association between duration, prior to initiating insulin for Type 2 diabetes mellitus (DM) and developing DR. Retrospective cross-sectional observational study included 1414 subjects having Type 2 DM. Insulin users were defined as subjects using insulin for glycemic control, and insulin nonusers as those either not using any antidiabetic treatment or using diet control or oral medications. The duration before initiating insulin after diagnosis was calculated by subtracting the duration of insulin usage from the duration of DM. DR was clinically graded using Klein's classification. SPSS (version 9.0) was used for statistical analysis. Insulin users had more incidence of DR (52.9% vs. 16.3%, P < 0.0001) and sight threatening DR (19.1% vs. 2.4%, P < 0.0001) in comparison to insulin nonusers. Among insulin users, longer duration of DM (odds ratio [OR] 1.12, 95% confidence interval [CI] 1.00-1.25, P = 0.044) and abdominal obesity (OR 1.15, 95% CI 1.02-1.29, P = 0.021) was associated with DR. The presence of DR was significantly associated with longer duration (≥5 years) prior to initiating insulin therapy, overall (38.0% vs. 62.0%, P = 0.013), and in subjects with suboptimal glycemic control (32.5% vs. 67.5%, P = 0.022). The presence of DR is significantly associated with longer duration of diabetes (>5 years) and sub-optimal glycemic control (glycosylated hemoglobin <7.0%). Among insulin users, abdominal obesity was found to be a significant predictor of DR; DR is associated with longer duration prior to initiating insulin therapy in Type 2 DM subjects with suboptimal glycemic control.

Web-based pathology practice examination usage.

PubMed

Klatt, Edward C

2014-01-01

General and subject specific practice examinations for students in health sciences studying pathology were placed onto a free public internet web site entitled web path and were accessed four clicks from the home web site menu. Multiple choice questions were coded into. html files with JavaScript functions for web browser viewing in a timed format. A Perl programming language script with common gateway interface for web page forms scored examinations and placed results into a log file on an internet computer server. The four general review examinations of 30 questions each could be completed in up to 30 min. The 17 subject specific examinations of 10 questions each with accompanying images could be completed in up to 15 min each. The results of scores and user educational field of study from log files were compiled from June 2006 to January 2014. The four general review examinations had 31,639 accesses with completion of all questions, for a completion rate of 54% and average score of 75%. A score of 100% was achieved by 7% of users, ≥90% by 21%, and ≥50% score by 95% of users. In top to bottom web page menu order, review examination usage was 44%, 24%, 17%, and 15% of all accessions. The 17 subject specific examinations had 103,028 completions, with completion rate 73% and average score 74%. Scoring at 100% was 20% overall, ≥90% by 37%, and ≥50% score by 90% of users. The first three menu items on the web page accounted for 12.6%, 10.0%, and 8.2% of all completions, and the bottom three accounted for no more than 2.2% each. Completion rates were higher for shorter 10 questions subject examinations. Users identifying themselves as MD/DO scored higher than other users, averaging 75%. Usage was higher for examinations at the top of the web page menu. Scores achieved suggest that a cohort of serious users fully completing the examinations had sufficient preparation to use them to support their pathology education.

Space station user's handbook (Revised)

NASA Technical Reports Server (NTRS)

1972-01-01

A modular space station concept that furnishes facilities which may be used for experimentation and application during earth orbit missions is described in a user's handbook. The subjects discussed are: (1) overall profile and mission activities for five year on-orbit program, (2) electromagnetic energy transmission through earth atmosphere, (3) effects of atmosphere in limiting resolution, and (4) the hydrological cycle as these subjects apply to the space station data acquisition function.

Identifying the needs of elderly, hearing-impaired persons: the importance and utility of hearing aid attributes.

PubMed

Meister, Hartmut; Lausberg, Isabel; Kiessling, Juergen; von Wedel, Hasso; Walger, Martin

2002-11-01

Older patients represent the majority of hearing-aid users. The needs of elderly, hearing-impaired subjects are not entirely identified. The present study aims to determine the importance of fundamental hearing-aid attributes and to elicit the utility of associated hypothetical hearing aids for older patients. This was achieved using a questionnaire-based conjoint analysis--a decompositional approach to preference measurement offering a realistic study design. A random sample of 200 experienced hearing-aid users participated in the study. Though three out of the six examined attributes revealed age-related dependencies, the only significant effect was found for the attribute "handling", which was considerably more important for older than younger hearing-aid users. A trend of decreasing importance of speech intelligibility in noise and increasing significance of speech in quiet was observed for subjects older than 70 years. In general, the utility of various hypothetical hearing aids was similar for older and younger subjects. Apart from the attribute "handling", older and younger subjects have comparable needs regarding hearing-aid features. On the basis of the examined attributes, there is no requirement for hearing aids designed specifically for elderly hearing-aid users, provided that ergonomic features are considered and the benefits of modern technology are made fully available for older patients.

Comparative study of smile analysis by subjective and computerized methods.

PubMed

Basting, Roberta Tarkany; da Trindade, Rita de Cássia Silva; Flório, Flávia Martão

2006-01-01

This study compared: 1) the subjective analyses of a smile done by specialists with advanced training and by general dentists; 2) the subjective analysis of a smile, or that associated with the face, by specialists with advanced training and general dentists; 3) subjective analysis using a computerized analysis of the smile by specialists with advanced training, verifying the midline, labial line, smile line, the line between commissures and the golden proportion. The sample consisted of 100 adults with natural dentition; 200 photographs were taken (100 of the smile and 100 of the entire face). Computerized analysis using AutoCAD software was performed, together with the subjective analyses of 2 groups of professionals (3 general dentists and 3 specialists with advanced training), using the following assessment factors: the midline, labial line, smile line, line between the commissures and the golden proportion. The smile itself and the smile associated with the entire face were recorded as being agreeable or not agreeable by the professionals. The McNemar test showed a highly significant difference (p=0.0000) among the subjective analyses performed by specialists compared to general dentists. Between the 2 groups of dental professionals, there were highly significant differences (p=0.0000) found between the subjective analyses of the smile and that of the face. The McNemar test showed statistical differences in all factors assessed, with the exception of the midline (p=0.1951), when the computerized analysis and subjective analysis of the specialists were compared. In order to establish harmony of the smile, it was not possible to establish a greater or lesser relevance among the factors analyzed.

The prevalence and natural history of urinary symptoms among recreational ketamine users.

PubMed

Winstock, Adam R; Mitcheson, Luke; Gillatt, David A; Cottrell, Angela M

2012-12-01

Study Type--Symptom prevalence (prospective cohort) Level of Evidence 1b. What's known on the subject? and What does the study add? Case series have described lower urinary tract symptoms associated with ketamine use including severe pain, frequency, haematuria and dysuria. Little is known regarding the frequency of symptoms, relationship of symptoms with dose and frequency of use and natural history of symptoms once the ketamine user has stopped. This study describes the prevalence of ketamine use in a population of recreational drug users in a dance music setting. It shows a dose-frequency relationship with ketamine use. It shows that urinary symptoms associated with recreational ketamine use may lead to a considerable demand on health resources in the primary-, secondary- and emergency-care settings. It shows that symptoms may improve once ketamine use is decreased. • To investigate the prevalence and natural history of urinary symptoms in a cohort of recreational ketamine users. • A purposeful sampling technique was used. • Between November 2009 and January 2010 participants were invited to undertake an on-line questionnaire promoted by a national dance music magazine and website. • Data regarding demographics and illicit drug-use were collected. • Among respondents reporting recent ketamine use, additional information detailing their ketamine use, experience of urinary symptoms and use of related healthcare services was obtained. • In all, 3806 surveys were completed, of which 1285 (33.8%) participants reported ketamine use within the last year. • Of the ketamine users, 17% were found to be dependent on the drug; 26.6% (340) of recent ketamine users reported experiencing urinary symptoms. • Urinary symptoms were significantly related to both dose of ketamine used and frequency of ketamine use. • Of 251 users reporting their experience of symptoms over time in relationship to their use of ketamine, 51% reported improvement in urinary symptoms upon cessation of use with only eight (3.8%) reporting deterioration after stopping use. • Urinary tract symptoms are reported in over a quarter of regular ketamine users. • A dose and frequency response relationship has been shown between ketamine use and urinary symptoms. • Both users and primary-care providers need to be educated about urinary symptoms that may arise in ketamine users. A multi-disciplinary approach promoting harm reduction, cessation and early referral is needed to manage individuals with ketamine-associated urinary tract symptoms to avoid progression to severe and irreversible urological pathologies. © 2012 BJU INTERNATIONAL.

On-Line Remote Catalog Access and Circulation Control System. Part I: Functional Specifications. Part II: User's Manual.

ERIC Educational Resources Information Center

International Business Machines Corp., Gaithersburg, MD. Data Processing Div.

The Ohio State University Libraries On-line Remote Catalog Access and Circulation Control System (LCS) began on-line operations with the conversion of one department library in November 1970. By December all 26 libraries had been converted to the automated system and LCS was fully operational one month ahead of schedule. LCS is designed as a…

76 FR 64427 - Illinois Central Railroad Company-Discontinuance of Trackage Rights Exemption-in Madison, Yazoo...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-18

... rights from GRYR by virtue of IC's retention of the trackage rights upon its sale of the Grenada Line to... line can be rerouted over other lines; (3) no formal complaint filed by a user of IC's trackage rights....S. District Court or has been decided in favor of complainant within the 2-year period; and (4) the...

75 FR 69520 - Indiana Southwestern Railway Co.-Abandonment Exemption-in Posey and Vanderburgh Counties, IN

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-12

... certified that: (1) No local traffic has moved over the line for at least 2 years; (2) there is no overhead traffic on the line to be rerouted; (3) no formal complaint filed by a user of rail service on the line... our website at http://www.stb.dot.gov . Decided: November 4, 2010. By the Board, Rachel D. Campbell...

SLAC Phone Directory: Search Form

Science.gov Websites

Facilities LCLS Hard X-Ray LCLS IT & Networking LCLS IT Photon Systems LCLS Instrumentation Dev LCLS Delivery Dept LCLS Science Research & DevDiv LCLS Soft X-Ray LCLS Technical Support LCLS User Beam Line Ops Sup SSRL MSD Hard X-rays SSRL MSD Soft X-rays SSRL MSDBeam Line Elec SSRL MSDBeam Line

Analysis of Delays in Transmitting Time Code Using an Automated Computer Time Distribution System

DTIC Science & Technology

1999-12-01

jlevine@clock. bldrdoc.gov Abstract An automated computer time distribution system broadcasts standard tune to users using computers and modems via...contributed to &lays - sofhareplatform (50% of the delay), transmission speed of time- codes (25OA), telephone network (lS%), modem and others (10’4). The... modems , and telephone lines. Users dial the ACTS server to receive time traceable to the national time scale of Singapore, UTC(PSB). The users can in

RATIONAL SPLINE SUBROUTINES

NASA Technical Reports Server (NTRS)

Schiess, J. R.

1994-01-01

Scientific data often contains random errors that make plotting and curve-fitting difficult. The Rational-Spline Approximation with Automatic Tension Adjustment algorithm lead to a flexible, smooth representation of experimental data. The user sets the conditions for each consecutive pair of knots:(knots are user-defined divisions in the data set) to apply no tension; to apply fixed tension; or to determine tension with a tension adjustment algorithm. The user also selects the number of knots, the knot abscissas, and the allowed maximum deviations from line segments. The selection of these quantities depends on the actual data and on the requirements of a particular application. This program differs from the usual spline under tension in that it allows the user to specify different tension values between each adjacent pair of knots rather than a constant tension over the entire data range. The subroutines use an automatic adjustment scheme that varies the tension parameter for each interval until the maximum deviation of the spline from the line joining the knots is less than or equal to a user-specified amount. This procedure frees the user from the drudgery of adjusting individual tension parameters while still giving control over the local behavior of the spline The Rational Spline program was written completely in FORTRAN for implementation on a CYBER 850 operating under NOS. It has a central memory requirement of approximately 1500 words. The program was released in 1988.

Metabolomics Characterization of U.S. and Japanese F-15 and C-130 Flight Line Crews Exposed to Jet Fuel Volatile Organic Compounds and Aerosols

DTIC Science & Technology

2014-09-30

resulted in the identification of metabolite patterns indicative of flight line exposure when compared to non -flight line control subjects...virtually non -invasive sample collection, minimal sample processing, robust and stable analytical platform, with excellent analytical and biological...identification of metabolite patterns indicative of flight line exposure when compared to non -flight line control subjects. Regardless of fuel (JP-4 or

Introducing ORACLE: Library Processing in a Multi-User Environment.

ERIC Educational Resources Information Center

Queensland Library Board, Brisbane (Australia).

Currently being developed by the State Library of Queensland, Australia, ORACLE (On-Line Retrieval of Acquisitions, Cataloguing, and Circulation Details for Library Enquiries) is a computerized library system designed to provide rapid processing of library materials in a multi-user environment. It is based on the Australian MARC format and fully…

A Computer Program for Testing Grammars On-Line.

ERIC Educational Resources Information Center

Gross, Louis N.

This paper describes a computer system which is intended to aid the linguist in building a transformational grammar. The program operates as a rule tester, performing three services for the user through sets of functions which allow the user to--specify, change, and print base trees (to which transformations would apply); define transformations…

A User-Centered View of Document Delivery and Interlibrary Loan.

ERIC Educational Resources Information Center

Martin, Harry S., III; Kendrick, Curtis L.

1994-01-01

Discusses reasons why libraries are being forced to seek new forms of information storage. A hypothetical scenario of user-initiated document delivery alternatives integrated with a search process used by a professor using the Harvard OnLine Library Information System is presented. Extensive notes elaborate on the process and the technology…

Altered subjective reward valuation among drug-deprived heavy marijuana users: Aversion to uncertainty

PubMed Central

Hefner, Kathryn R.; Starr, Mark. J.; Curtin, John. J.

2015-01-01

Marijuana is the most commonly used illicit drug in the United States and its use is rising. Nonetheless, scientific efforts to clarify the risk for addiction and other harm associated with marijuana use have been lacking. Maladaptive decision-making is a cardinal feature of addiction that is likely to emerge in heavy users. In particular, distorted subjective reward valuation related to homeostatic or allostatic processes has been implicated for many drugs of abuse. Selective changes in responses to uncertainty have been observed in response to intoxication and deprivation from various drugs of abuse. To assess for these potential neuroadaptive changes in reward valuation associated with marijuana deprivation, we examined the subjective value of uncertain and certain rewards among deprived and non-deprived heavy marijuana users in a behavioral economics decision-making task. Deprived users displayed reduced valuation of uncertain rewards, particularly when these rewards were more objectively valuable. This uncertainty aversion increased with increasing quantity of marijuana use. These results suggest comparable decision-making vulnerability from marijuana use as other drugs of abuse, and highlights targets for intervention. PMID:26595464

Workload measurement in a communication application operated through a P300-based brain-computer interface

NASA Astrophysics Data System (ADS)

Riccio, A.; Leotta, F.; Bianchi, L.; Aloise, F.; Zickler, C.; Hoogerwerf, E.-J.; Kübler, A.; Mattia, D.; Cincotti, F.

2011-04-01

Advancing the brain-computer interface (BCI) towards practical applications in technology-based assistive solutions for people with disabilities requires coping with problems of accessibility and usability to increase user acceptance and satisfaction. The main objective of this study was to introduce a usability-oriented approach in the assessment of BCI technology development by focusing on evaluation of the user's subjective workload and satisfaction. The secondary aim was to compare two applications for a P300-based BCI. Eight healthy subjects were asked to use an assistive technology solution which integrates the P300-based BCI with commercially available software under two conditions—visual stimuli needed to evoke the P300 response were either overlaid onto the application's graphical user interface or presented on a separate screen. The two conditions were compared for effectiveness (level of performance), efficiency (subjective workload measured by means of NASA-TXL) and satisfaction of the user. Although no significant difference in usability could be detected between the two conditions, the methodology proved to be an effective tool to highlight weaknesses in the technical solution.

Metabolite alterations in basal ganglia associated with methamphetamine-related psychiatric symptoms. A proton MRS study.

PubMed

Sekine, Yoshimoto; Minabe, Yoshio; Kawai, Masayoshi; Suzuki, Katsuaki; Iyo, Masaomi; Isoda, Haruo; Sakahara, Harumi; Ashby, Charles R; Takei, Nori; Mori, Norio

2002-09-01

Following the chronic use of methamphetamine, some individuals experience psychosis and anxiety. One reason may be the persistence of metabolite abnormalities in the brain of currently abstinent former methamphetamine users. In this study, N-acetylaspartate (NAA), creatine plus phosphocreatine (Cr+PCr), and choline-containing compound (Cho) levels were measured in the left and right basal ganglia using proton magnetic resonance spectroscopy (MRS) in 13 abstinent methamphetamine users and 11 healthy comparison subjects with no history of illicit drug use. The methamphetamine users showed a significantly reduced Cr+PCr/Cho ratio in the bilateral basal ganglia compared with the healthy comparison subjects. Furthermore, the reduction in the Cr+PCr/Cho ratio was significantly correlated with the duration of methamphetamine use and with the severity of residual psychiatric symptoms. NAA/Cho ratios in the bilateral basal ganglia did not significantly differ between methamphetamine users and comparison subjects. These findings suggest that protracted use of methamphetamine may cause metabolite alterations in the basal ganglia. Furthermore, residual psychiatric symptoms may be attributable to the metabolite alterations in the basal ganglia.

SIG: a general-purpose signal processing program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lager, D.; Azevedo, S.

1986-02-01

SIG is a general-purpose signal processing, analysis, and display program. Its main purpose is to perform manipulations on time- and frequency-domain signals. It also accommodates other representations for data such as transfer function polynomials. Signal processing operations include digital filtering, auto/cross spectral density, transfer function/impulse response, convolution, Fourier transform, and inverse Fourier transform. Graphical operations provide display of signals and spectra, including plotting, cursor zoom, families of curves, and multiple viewport plots. SIG provides two user interfaces with a menu mode for occasional users and a command mode for more experienced users. Capability exits for multiple commands per line, commandmore » files with arguments, commenting lines, defining commands, automatic execution for each item in a repeat sequence, etc. SIG is presently available for VAX(VMS), VAX (BERKELEY 4.2 UNIX), SUN (BERKELEY 4.2 UNIX), DEC-20 (TOPS-20), LSI-11/23 (TSX), and DEC PRO 350 (TSX). 4 refs., 2 figs.« less

Simultaneous operation of two soft x-ray free-electron lasers driven by one linear accelerator

NASA Astrophysics Data System (ADS)

Faatz, B.; Plönjes, E.; Ackermann, S.; Agababyan, A.; Asgekar, V.; Ayvazyan, V.; Baark, S.; Baboi, N.; Balandin, V.; von Bargen, N.; Bican, Y.; Bilani, O.; Bödewadt, J.; Böhnert, M.; Böspflug, R.; Bonfigt, S.; Bolz, H.; Borges, F.; Borkenhagen, O.; Brachmanski, M.; Braune, M.; Brinkmann, A.; Brovko, O.; Bruns, T.; Castro, P.; Chen, J.; Czwalinna, M. K.; Damker, H.; Decking, W.; Degenhardt, M.; Delfs, A.; Delfs, T.; Deng, H.; Dressel, M.; Duhme, H.-T.; Düsterer, S.; Eckoldt, H.; Eislage, A.; Felber, M.; Feldhaus, J.; Gessler, P.; Gibau, M.; Golubeva, N.; Golz, T.; Gonschior, J.; Grebentsov, A.; Grecki, M.; Grün, C.; Grunewald, S.; Hacker, K.; Hänisch, L.; Hage, A.; Hans, T.; Hass, E.; Hauberg, A.; Hensler, O.; Hesse, M.; Heuck, K.; Hidvegi, A.; Holz, M.; Honkavaara, K.; Höppner, H.; Ignatenko, A.; Jäger, J.; Jastrow, U.; Kammering, R.; Karstensen, S.; Kaukher, A.; Kay, H.; Keil, B.; Klose, K.; Kocharyan, V.; Köpke, M.; Körfer, M.; Kook, W.; Krause, B.; Krebs, O.; Kreis, S.; Krivan, F.; Kuhlmann, J.; Kuhlmann, M.; Kube, G.; Laarmann, T.; Lechner, C.; Lederer, S.; Leuschner, A.; Liebertz, D.; Liebing, J.; Liedtke, A.; Lilje, L.; Limberg, T.; Lipka, D.; Liu, B.; Lorbeer, B.; Ludwig, K.; Mahn, H.; Marinkovic, G.; Martens, C.; Marutzky, F.; Maslocv, M.; Meissner, D.; Mildner, N.; Miltchev, V.; Molnar, S.; Mross, D.; Müller, F.; Neumann, R.; Neumann, P.; Nölle, D.; Obier, F.; Pelzer, M.; Peters, H.-B.; Petersen, K.; Petrosyan, A.; Petrosyan, G.; Petrosyan, L.; Petrosyan, V.; Petrov, A.; Pfeiffer, S.; Piotrowski, A.; Pisarov, Z.; Plath, T.; Pototzki, P.; Prandolini, M. J.; Prenting, J.; Priebe, G.; Racky, B.; Ramm, T.; Rehlich, K.; Riedel, R.; Roggli, M.; Röhling, M.; Rönsch-Schulenburg, J.; Rossbach, J.; Rybnikov, V.; Schäfer, J.; Schaffran, J.; Schlarb, H.; Schlesselmann, G.; Schlösser, M.; Schmid, P.; Schmidt, C.; Schmidt-Föhre, F.; Schmitz, M.; Schneidmiller, E.; Schöps, A.; Scholz, M.; Schreiber, S.; Schütt, K.; Schütz, U.; Schulte-Schrepping, H.; Schulz, M.; Shabunov, A.; Smirnov, P.; Sombrowski, E.; Sorokin, A.; Sparr, B.; Spengler, J.; Staack, M.; Stadler, M.; Stechmann, C.; Steffen, B.; Stojanovic, N.; Sychev, V.; Syresin, E.; Tanikawa, T.; Tavella, F.; Tesch, N.; Tiedtke, K.; Tischer, M.; Treusch, R.; Tripathi, S.; Vagin, P.; Vetrov, P.; Vilcins, S.; Vogt, M.; de Zubiaurre Wagner, A.; Wamsat, T.; Weddig, H.; Weichert, G.; Weigelt, H.; Wentowski, N.; Wiebers, C.; Wilksen, T.; Willner, A.; Wittenburg, K.; Wohlenberg, T.; Wortmann, J.; Wurth, W.; Yurkov, M.; Zagorodnov, I.; Zemella, J.

2016-06-01

Extreme-ultraviolet to x-ray free-electron lasers (FELs) in operation for scientific applications are up to now single-user facilities. While most FELs generate around 100 photon pulses per second, FLASH at DESY can deliver almost two orders of magnitude more pulses in this time span due to its superconducting accelerator technology. This makes the facility a prime candidate to realize the next step in FELs—dividing the electron pulse trains into several FEL lines and delivering photon pulses to several users at the same time. Hence, FLASH has been extended with a second undulator line and self-amplified spontaneous emission (SASE) is demonstrated in both FELs simultaneously. FLASH can now deliver MHz pulse trains to two user experiments in parallel with individually selected photon beam characteristics. First results of the capabilities of this extension are shown with emphasis on independent variation of wavelength, repetition rate, and photon pulse length.

Notebook computer use with different monitor tilt angle: effects on posture, muscle activity and discomfort of neck pain users.

PubMed

Chiou, Wen-Ko; Chou, Wei-Ying; Chen, Bi-Hui

2012-01-01

This study aimed to evaluate the posture, muscle activities, and self reported discomforts of neck pain notebook computer users on three monitor tilt conditions: 100°, 115°, and 130°. Six subjects were recruited in this study to completed typing tasks. Results showed subjects have a trend to show the forward head posture in the condition that monitor was set at 100°, and the significant less neck and shoulder discomfort were noted in the condition that monitor was set at 130°. These result suggested neck pain notebook user to set their monitor tilt angle at 130°.

Pitch Adaptation Patterns in Bimodal Cochlear Implant Users: Over Time and After Experience

PubMed Central

Reiss, Lina A.J.; Ito, Rindy A.; Eggleston, Jessica L.; Liao, Selena; Becker, Jillian J.; Lakin, Carrie E.; Warren, Frank M.; McMenomey, Sean O.

2014-01-01

Background Pitch plasticity has been observed in Hybrid cochlear implant (CI) users. Does pitch plasticity also occur in bimodal CI users with traditional long-electrode CIs, and is pitch adaptation pattern associated with electrode discrimination or speech recognition performance? Objective Characterize pitch adaptation patterns in long-electrode CI users, correlate these patterns with electrode discrimination and speech perception outcomes, and analyze which subject factors are associated with the different patterns. Methods Electric-to-acoustic pitch matches were obtained in 19 subjects over time from CI activation to at least 12 months after activation, and in a separate group of 18 subjects in a single visit after at least 24 months of CI experience. Audiometric thresholds, electrode discrimination performance, and speech perception scores were also measured. Results Subjects measured over time had pitch adaptation patterns that fit one of the following categories: 1) “Pitch-adapting”, i.e. the mismatch between perceived electrode pitch and the corresponding frequency-to-electrode allocations decreased; 2) “Pitch-dropping”, i.e. the pitches of multiple electrodes dropped and converged to a similar low pitch; 3) “Pitch-unchanging”, i.e. electrode pitches did not change. Subjects measured after CI experience had a parallel set of adaptation patterns: 1) “Matched-pitch”, i.e. the electrode pitch was matched to the frequency allocation; 2) “Low-pitch”, i.e. the pitches of multiple electrodes were all around the lowest frequency allocation; 3) “Nonmatched-pitch”, i.e. the pitch patterns were compressed relative to the frequency allocations and did not fit either the matched-pitch or low-pitch categories. Unlike Hybrid CI users which were mostly in the pitch-adapting/matched-pitch category, the majority of bimodal CI users were in the latter two categories, pitch-dropping/low-pitch or pitch-unchanging/nonmatched-pitch. Subjects with pitch-adapting or matched-pitch patterns tended to have better low-frequency thresholds than subjects in the latter categories. Changes in electrode discrimination over time were not associated with changes in pitch differences between electrodes. Reductions in speech perception scores over time showed a weak but nonsignificant association with dropping-pitch patterns. Conclusions Bimodal CI users with more residual hearing may have somewhat greater similarity to Hybrid CI users and be more likely to adapt pitch perception to reduce mismatch with the frequencies allocated to the electrodes and the acoustic hearing. In contrast, bimodal CI users with less residual hearing exhibit either no adaptation, or surprisingly, a third pattern in which the pitches of the basal electrodes drop to match the frequency range allocated to the most apical electrode. The lack of association of electrode discrimination changes with pitch changes suggests that electrode discrimination does not depend on perceived pitch differences between electrodes, but rather on some other characteristics such as timbre. In contrast, speech perception may depend more on pitch perception and the ability to distinguish pitch between electrodes, especially since during multi-electrode stimulation, cues such as timbre may be less useful for discrimination. PMID:25319401

Crescent Evaluation : appendix F : state-line beacon project : user case studies

DOT National Transportation Integrated Search

1994-02-01

The essence of the AVI "Beacon" concept as it applies to the HELP organization would be to provide location, date, and tune information from the roadside to the on-board computer (OBC). A roadside transmit beacon would be located on the state lines a...

A Grammar-based Approach for Modeling User Interactions and Generating Suggestions During the Data Exploration Process.

PubMed

Dabek, Filip; Caban, Jesus J

2017-01-01

Despite the recent popularity of visual analytics focusing on big data, little is known about how to support users that use visualization techniques to explore multi-dimensional datasets and accomplish specific tasks. Our lack of models that can assist end-users during the data exploration process has made it challenging to learn from the user's interactive and analytical process. The ability to model how a user interacts with a specific visualization technique and what difficulties they face are paramount in supporting individuals with discovering new patterns within their complex datasets. This paper introduces the notion of visualization systems understanding and modeling user interactions with the intent of guiding a user through a task thereby enhancing visual data exploration. The challenges faced and the necessary future steps to take are discussed; and to provide a working example, a grammar-based model is presented that can learn from user interactions, determine the common patterns among a number of subjects using a K-Reversible algorithm, build a set of rules, and apply those rules in the form of suggestions to new users with the goal of guiding them along their visual analytic process. A formal evaluation study with 300 subjects was performed showing that our grammar-based model is effective at capturing the interactive process followed by users and that further research in this area has the potential to positively impact how users interact with a visualization system.

Does gravity influence the visual line bisection task?

PubMed

Drakul, A; Bockisch, C J; Tarnutzer, A A

2016-08-01

The visual line bisection task (LBT) is sensitive to perceptual biases of visuospatial attention, showing slight leftward (for horizontal lines) and upward (for vertical lines) errors in healthy subjects. It may be solved in an egocentric or allocentric reference frame, and there is no obvious need for graviceptive input. However, for other visual line adjustments, such as the subjective visual vertical, otolith input is integrated. We hypothesized that graviceptive input is incorporated when performing the LBT and predicted reduced accuracy and precision when roll-tilted. Twenty healthy right-handed subjects repetitively bisected Earth-horizontal and body-horizontal lines in darkness. Recordings were obtained before, during, and after roll-tilt (±45°, ±90°) for 5 min each. Additionally, bisections of Earth-vertical and oblique lines were obtained in 17 subjects. When roll-tilted ±90° ear-down, bisections of Earth-horizontal (i.e., body-vertical) lines were shifted toward the direction of the head (P < 0.001). However, after correction for vertical line-bisection errors when upright, shifts disappeared. Bisecting body-horizontal lines while roll-tilted did not cause any shifts. The precision of Earth-horizontal line bisections decreased (P ≤ 0.006) when roll-tilted, while no such changes were observed for body-horizontal lines. Regardless of the trial condition and paradigm, the scanning direction of the bisecting cursor (leftward vs. rightward) significantly (P ≤ 0.021) affected line bisections. Our findings reject our hypothesis and suggest that gravity does not modulate the LBT. Roll-tilt-dependent shifts are instead explained by the headward bias when bisecting lines oriented along a body-vertical axis. Increased variability when roll-tilted likely reflects larger variability when bisecting body-vertical than body-horizontal lines. Copyright © 2016 the American Physiological Society.

Acceptable noise level (ANL) with Danish and non-semantic speech materials in adult hearing-aid users.

PubMed

Olsen, Steen Østergaard; Lantz, Johannes; Nielsen, Lars Holme; Brännström, K Jonas

2012-09-01

The acceptable noise level (ANL) test is used for quantification of the amount of background noise subjects accept when listening to speech. This study investigates Danish hearing-aid users' ANL performance using Danish and non-semantic speech signals, the repeatability of ANL, and the association between ANL and outcome of the international outcome inventory for hearing aids (IOI-HA). ANL was measured in three conditions in both ears at two test sessions. Subjects completed the IOI-HA and the ANL questionnaire. Sixty-three Danish hearing-aid users; fifty-seven subjects were full time users and 6 were part time/non users of hearing aids according to the ANL questionnaire. ANLs were similar to results with American English speech material. The coefficient of repeatability (CR) was 6.5-8.8 dB. IOI-HA scores were not associated to ANL. Danish and non-semantic ANL versions yield results similar to the American English version. The magnitude of the CR indicates that ANL with Danish and non-semantic speech materials is not suitable for prediction of individual patterns of future hearing-aid use or evaluation of individual benefit from hearing-aid features. The ANL with Danish and non-semantic speech materials is not related to IOI-HA outcome.

Evaluation of a wireless wearable tongue–computer interface by individuals with high-level spinal cord injuries

PubMed Central

Huo, Xueliang; Ghovanloo, Maysam

2010-01-01

The tongue drive system (TDS) is an unobtrusive, minimally invasive, wearable and wireless tongue–computer interface (TCI), which can infer its users' intentions, represented in their volitional tongue movements, by detecting the position of a small permanent magnetic tracer attached to the users' tongues. Any specific tongue movements can be translated into user-defined commands and used to access and control various devices in the users' environments. The latest external TDS (eTDS) prototype is built on a wireless headphone and interfaced to a laptop PC and a powered wheelchair. Using customized sensor signal processing algorithms and graphical user interface, the eTDS performance was evaluated by 13 naive subjects with high-level spinal cord injuries (C2–C5) at the Shepherd Center in Atlanta, GA. Results of the human trial show that an average information transfer rate of 95 bits/min was achieved for computer access with 82% accuracy. This information transfer rate is about two times higher than the EEG-based BCIs that are tested on human subjects. It was also demonstrated that the subjects had immediate and full control over the powered wheelchair to the extent that they were able to perform complex wheelchair navigation tasks, such as driving through an obstacle course. PMID:20332552

A Method for Efficient Searching at Online Shopping

NASA Astrophysics Data System (ADS)

Sanjo, Tomomi; Nagata, Moiro

In recent years, online shopping has been popularized. However, the users can not find efficiently their items at on-line markets. This paper proposes an engine to find items easily at the online market. This engine has the following facilities. First, it presents information in a fixed format. Second, the user can find items by selected keywords. Third, it presents only necessary information by using his/her history. Finally, it has a customize function for each user. Moreover, the system asks the users to down load a page of recommended items. We show the effectives of our proposal with some experiments.

Accounting for phase drifts in SSVEP-based BCIs by means of biphasic stimulation.

PubMed

Wu, Hung-Yi; Lee, Po-Lei; Chang, Hsiang-Chih; Hsieh, Jen-Chuen

2011-05-01

This study proposes a novel biphasic stimulation technique to solve the issue of phase drifts in steady-state visual evoked potential (SSVEPs) in phase-tagged systems. Phase calibration was embedded in stimulus sequences using a biphasic flicker, which is driven by a sequence with alternating reference and phase-shift states. Nine subjects were recruited to participate in off-line and online tests. Signals were bandpass filtered and segmented by trigger signals into reference and phase-shift epochs. Frequency components of SSVEP in the reference and phase-shift epochs were extracted using the Fourier method with a 50% overlapped sliding window. The real and imaginary parts of the SSVEP frequency components were organized into complex vectors in each epoch. Hotelling's t-square test was used to determine the significances of nonzero mean vectors. The rejection of noisy data segments and the validation of gaze detections were made based on p values. The phase difference between the valid mean vectors of reference and phase-shift epochs was used to identify user's gazed targets in this system. Data showed an average information transfer rate of 44.55 and 38.21 bits/min in off-line and online tests, respectively. © 2011 IEEE

A study investigating the acute dose-response effects of 13 mg and 17 mg Delta 9- tetrahydrocannabinol on cognitive-motor skills, subjective and autonomic measures in regular users of marijuana.

PubMed

Weinstein, A; Brickner, O; Lerman, H; Greemland, M; Bloch, M; Lester, H; Chisin, R; Sarne, Y; Mechoulam, R; Bar-Hamburger, R; Freedman, N; Even-Sapir, E

2008-06-01

Heavy use of marijuana is claimed to damage critical skills related to short-term memory, visual scanning and attention. Motor skills and driving safety may be compromised by the acute effects of marijuana. The aim of this study was to investigate the acute effects of 13 mg and 17 mg Delta 9-tetrahydrocannabinol (THC) on skills important for coordinated movement and driving and on subjective and autonomic measures in regular users of marijuana. Fourteen regular users of marijuana were enrolled. Each subject was tested on two separate days. On each test day, subjects smoked two low-nicotine cigarettes, one with and the other without THC. Seventeen mg THC was included in the cigarette on one test day and 13 mg on the other day. The sequence of cigarette types was unknown to the subject. During smoking, heart rate and blood pressure were monitored, and the subjects performed a virtual reality maze task requiring attention and motor coordination, followed by 3 other cognitive tasks (Wisconsin Card Sorting Test (WCST), a "gambling" task and estimation of time and distance from an approaching car). After smoking a cigarette with 17 mg THC, regular marijuana users hit the walls more often on the virtual maze task than after smoking cigarettes without THC; this effect was not seen in patients after they smoked cigarettes with 13 mg THC. Performance in the WCST was affected with 17 mg THC and to a lesser extent with the use of 13 mg THC. Decision making in the gambling task was affected after smoking cigarettes with 17 mg THC, but not with 13 m THC. Smoking cigarettes with 13 and 17 mg THC increased subjective ratings of pleasure and satisfaction, drug "effect" and drug "high". These findings imply that smoking of 17 mg THC results in impairment of cognitive-motor skills that could be important for coordinated movement and driving, whereas the lower dose of 13 mg THC appears to cause less impairment of such skills in regular users of marijuana.

Graphing within-subjects confidence intervals using SPSS and S-Plus.

PubMed

Wright, Daniel B

2007-02-01

Within-subjects confidence intervals are often appropriate to report and to display. Loftus and Masson (1994) have reported methods to calculate these, and their use is becoming common. In the present article, procedures for calculating within-subjects confidence intervals in SPSS and S-Plus are presented (an R version is on the accompanying Web site). The procedure in S-Plus allows the user to report the bias corrected and adjusted bootstrap confidence intervals as well as the standard confidence intervals based on traditional methods. The presented code can be easily altered to fit the individual user's needs.

Value-added Data Services at the Goddard Earth Sciences Data and Information Services Center

NASA Technical Reports Server (NTRS)

Leptoukh, Gregory G.; Alcott, Gary T.; Kempler, Steven J.; Lynnes, Christopher S.; Vollmer, Bruce E.

2004-01-01

The NASA Goddard Earth Sciences Data and Information Services Center (GES DISC), in addition to serving the Earth Science community as one of the major Distributed Active Archives Centers (DAACs), provides much more than just data. Among the value-added services available to general users are subsetting data spatially and/or by parameter, online analysis (to avoid downloading unnecessarily all the data), and assistance in obtaining data from other centers. Services available to data producers and high-volume users include consulting on building new products with standard formats and metadata and construction of data management systems. A particularly useful service is data processing at the DISC (i.e., close to the input data) with the users algorithm. This can take a number of different forms: as a configuration-managed algorithm within the main processing stream; as a stand-alone program next to the on-line data storage; as build-it-yourself code within the Near-Archive Data Mining (NADM) system; or as an on-the-fly analysis with simple algorithms embedded into the web-based tools. Partnerships between the GES DISC and scientists, both producers and users, allow the scientists to concentrate on science, while the GES DISC handles the data management, e.g., formats, integration, and data processing. The existing data management infrastructure at the GES DISC supports a wide spectrum of options: from simple data support to sophisticated on-line analysis tools, producing economies of scale and rapid time-to-deploy. At the same time, such partnerships allow the GES DISC to serve the user community more efficiently and to better prioritize on-line holdings. Several examples of successful partnerships are described in the presentation.

Checking an integrated model of web accessibility and usability evaluation for disabled people.

PubMed

Federici, Stefano; Micangeli, Andrea; Ruspantini, Irene; Borgianni, Stefano; Corradi, Fabrizio; Pasqualotto, Emanuele; Olivetti Belardinelli, Marta

2005-07-08

A combined objective-oriented and subjective-oriented method for evaluating accessibility and usability of web pages for students with disability was tested. The objective-oriented approach is devoted to verifying the conformity of interfaces to standard rules stated by national and international organizations responsible for web technology standardization, such as W3C. Conversely, the subjective-oriented approach allows assessing how the final users interact with the artificial system, accessing levels of user satisfaction based on personal factors and environmental barriers. Five kinds of measurements were applied as objective-oriented and subjective-oriented tests. Objective-oriented evaluations were performed on the Help Desk web page for students with disability, included in the website of a large Italian state university. Subjective-oriented tests were administered to 19 students labeled as disabled on the basis of their own declaration at the University enrolment: 13 students were tested by means of the SUMI test and six students by means of the 'Cooperative evaluation'. Objective-oriented and subjective-oriented methods highlighted different and sometimes conflicting results. Both methods have pointed out much more consistency regarding levels of accessibility than of usability. Since usability is largely affected by individual differences in user's own (dis)abilities, subjective-oriented measures underscored the fact that blind students encountered much more web surfing difficulties.

Psychedelic symptoms of cannabis and cocaine use as a function of trait impulsivity.

PubMed

van Wel, J H P; Spronk, D B; Kuypers, K P C; Theunissen, E L; Toennes, S W; Verkes, R J; Ramaekers, J G

2015-03-01

Trait impulsivity has been linked to addiction in humans. It has been suggested that drug users with high trait impulsivity levels are more sensitive to subjective drug intoxication. This study assessed whether subjective response to drugs differs between drug users with normal or high levels of trait impulsivity. Regular drug users (N = 122) received doses of cocaine HCl, cannabis, and placebo in a three-way crossover study. Their mood, dissociative state, and psychedelic symptoms were measured with subjective rating scales (CADDS, Bowdle, POMS). Trait impulsivity was assessed with the Barratt Impulsiveness Scale. Cannabis increased dissociation and psychedelic state, as well as fatigue, confusion, depression and anxiety, and decreased arousal, positive mood, vigor, friendliness, and elation. Cocaine increased dissociation, psychedelic state, vigor, friendliness, elation, positive mood, anxiety and arousal, while decreasing fatigue. Only a few subjective items revealed a drug × trait impulsivity interaction, suggesting that psychedelic symptoms were most intense in high impulsivity subjects. Trait impulsiveness ratings were negatively correlated with ratings of vigor (r = -.197) and positively correlated with ratings of loss of thought control (r = .237) during cannabis intoxication. It is concluded that a broad association between trait impulsivity and psychedelic subjective drug experience appears to be absent. © The Author(s) 2015.

User Satisfaction as a Measure of System Performance

ERIC Educational Resources Information Center

Griffiths, Jillian R.; Johnson, Frances; Hartley, Richard J.

2007-01-01

It is evident from previous research that user satisfaction is a multidimensional, subjective variable which can be affected by many factors other than performance of the system or searcher. This article draws on information retrieval and information systems literature in an attempt to understand what user satisfaction is, how it is measured, what…

IDEN2-A program for visual identification of spectral lines and energy levels in optical spectra of atoms and simple molecules

NASA Astrophysics Data System (ADS)

Azarov, V. I.; Kramida, A.; Vokhmentsev, M. Ya.

2018-04-01

The article describes a Java program that can be used in a user-friendly way to visually identify spectral lines observed in complex spectra with theoretically predicted transitions between atomic or molecular energy levels. The program arranges various information about spectral lines and energy levels in such a way that line identification and determination of positions of experimentally observed energy levels become much easier tasks that can be solved fast and efficiently.

Solving the "Hidden Line" Problem

NASA Technical Reports Server (NTRS)

1984-01-01

David Hedgley Jr., a mathematician at Dryden Flight Research Center, has developed an accurate computer program that considers whether a line in a graphic model of a three dimensional object should or should not be visible. The Hidden Line Computer Code, program automatically removes superfluous lines and permits the computer to display an object from specific viewpoints, just as the human eye would see it. Users include Rowland Institute for Science in Cambridge, MA, several departments of Lockheed Georgia Co., and Nebraska Public Power District (NPPD).

Development of the PEFP's beam line BPM

NASA Astrophysics Data System (ADS)

Ryu, Jin-Yeong; Kwon, Hyeok-Jung; Jang, Ji-Ho; Kim, Han-Sung; Seol, Kyung-Tae; Cho, Yong-Sub

2013-01-01

The Proton Engineering Frontier Project (PEFP) has 20-MeV and 100-MeV beam lines to supply proton beams to users. A stripline-type Beam Position Monitor (BPM) was designed and fabricated in order to measure the beam's position in the beam line. The RF properties of the BPM were measured and compared with the simulation. After the sensitivity of the BPM at a test stand had been obtained, we performed a beam test in a test beam line of the PEFP 20-MeV proton linac.

A Multimodal Deep Log-Based User Experience (UX) Platform for UX Evaluation.

PubMed

Hussain, Jamil; Khan, Wajahat Ali; Hur, Taeho; Bilal, Hafiz Syed Muhammad; Bang, Jaehun; Hassan, Anees Ul; Afzal, Muhammad; Lee, Sungyoung

2018-05-18

The user experience (UX) is an emerging field in user research and design, and the development of UX evaluation methods presents a challenge for both researchers and practitioners. Different UX evaluation methods have been developed to extract accurate UX data. Among UX evaluation methods, the mixed-method approach of triangulation has gained importance. It provides more accurate and precise information about the user while interacting with the product. However, this approach requires skilled UX researchers and developers to integrate multiple devices, synchronize them, analyze the data, and ultimately produce an informed decision. In this paper, a method and system for measuring the overall UX over time using a triangulation method are proposed. The proposed platform incorporates observational and physiological measurements in addition to traditional ones. The platform reduces the subjective bias and validates the user's perceptions, which are measured by different sensors through objectification of the subjective nature of the user in the UX assessment. The platform additionally offers plug-and-play support for different devices and powerful analytics for obtaining insight on the UX in terms of multiple participants.

Abnormal maximal finger tapping in abstinent cannabis users.

PubMed

Flavel, Stanley C; White, Jason M; Todd, Gabrielle

2013-11-01

To investigate movement speed and rhythmicity in abstinent cannabis users, we hypothesized that abstinent cannabis users exhibit decreased maximal finger tapping frequency and increased variability of tapping compared with non-drug users. The study involved 10 healthy adult cannabis users and 10 age-matched and gender-matched controls with no history of illicit drug use. Subjects underwent a series of screening tests prior to participation. Subjects were then asked to tap a strain gauge as fast as possible with the index finger of their dominant hand (duration 5 s). The average intertap interval did not significantly differ between groups, but the coefficient of variation of the intertap interval was significantly greater in the cannabis group than in controls (p=0.011). The cannabis group also exhibited a slow tapping frequency at the beginning of the task. Rhythmicity of finger tapping is abnormal in individuals with a history of cannabis use. The abnormality appears to be long lasting and adds to the list of functional changes present in abstinent cannabis users. Copyright © 2013 John Wiley & Sons, Ltd.

Subjective hearing-related quality-of-life is a major factor in the decision to continue using hearing aids among older persons.

PubMed

Maeda, Yukihide; Sugaya, Akiko; Nagayasu, Rie; Nakagawa, Atsuko; Nishizaki, Kazunori

2016-09-01

Audiological parameters alone do not determine the choice to use hearing aids (HA). Subjective hearing-related QoL is a major factor that determines whether or not an older person will continue to wear HA. This study aimed to identify which audiological parameters and quality-of-life (QoL) measures determine whether or not older persons will continue wearing HA. Charts of 157 patients aged ≥65 years who attended the HA service unit at the Otolaryngology Department were retrospectively reviewed. After HA fitting and a trial, the patients were divided into groups, depending upon whether or not they wanted to continue wearing the HA (users, 58.2%; non-users, 41.8%) and then audiological parameters were compared between them. At least 4 months after the HA fitting, the self-reported QoL questionnaire, Hearing Handicap Inventory for the Elderly (HHIE), was mailed to all 157 patients and HHIE scores were compared between HA users and non-users. Speech discrimination score and dynamic range did not significantly differ between HA users and non-users. A difference in the average hearing threshold was marginally significant. The response rate to the HHIE was 65.2%. Total HHIE and emotional scores were higher (more impaired) among HA users than non-users.

Fitting prelingually deafened adult cochlear implant users based on electrode discrimination performance.

PubMed

Debruyne, Joke A; Francart, Tom; Janssen, A Miranda L; Douma, Kim; Brokx, Jan P L

2017-03-01

This study investigated the hypotheses that (1) prelingually deafened CI users do not have perfect electrode discrimination ability and (2) the deactivation of non-discriminable electrodes can improve auditory performance. Electrode discrimination difference limens were determined for all electrodes of the array. The subjects' basic map was subsequently compared to an experimental map, which contained only discriminable electrodes, with respect to speech understanding in quiet and in noise, listening effort, spectral ripple discrimination and subjective appreciation. Subjects were six prelingually deafened, late implanted adults using the Nucleus cochlear implant. Electrode discrimination difference limens across all subjects and electrodes ranged from 0.5 to 7.125, with significantly larger limens for basal electrodes. No significant differences were found between the basic map and the experimental map on auditory tests. Subjective appreciation was found to be significantly poorer for the experimental map. Prelingually deafened CI users were unable to discriminate between all adjacent electrodes. There was no difference in auditory performance between the basic and experimental map. Potential factors contributing to the absence of improvement with the experimental map include the reduced number of maxima, incomplete adaptation to the new frequency allocation, and the mainly basal location of deactivated electrodes.

Designing Messaging to Engage Patients in an Online Suicide Prevention Intervention: Survey Results From Patients With Current Suicidal Ideation

PubMed Central

Lungu, Anita; Richards, Julie; Simon, Gregory E; Clingan, Sarah; Siler, Jaeden; Snyder, Lorilei; Ludman, Evette

2014-01-01

Background Computerized, Internet-delivered interventions can be efficacious; however, uptake and maintaining sustained client engagement are still big challenges. We see the development of effective engagement strategies as the next frontier in online health interventions, an area where much creative research has begun. We also argue that for engagement strategies to accomplish their purpose with novel targeted populations, they need to be tailored to such populations (ie, content is designed with the target population in mind). User-centered design frameworks provide a theoretical foundation for increasing user engagement and uptake by including users in development. However, deciding how to implement this approach to enage users in mental health intervention development is challenging. Objective The aim of this study was to get user input and feedback on acceptability of messaging content intended to engage suicidal individuals. Methods In March 2013, clinic intake staff distributed flyers announcing the study, “Your Feedback Counts” to potential participants (individuals waiting to be seen for a mental health appointment) together with the Patient Health Questionnaire. The flyer explained that a score of two or three (“more than half the days” or “nearly every day” respectively) on the suicide ideation question made them eligible to provide feedback on components of a suicide prevention intervention under development. The patient could access an anonymous online survey by following a link. After providing consent online, participants completed the anonymous survey. Results Thirty-four individuals provided data on past demographic information. Participants reported that they would be most drawn to an intervention where they knew that they were cared about, that was personalized, that others like them had found it helpful, and that included examples with real people. Participants preferred email invitations with subject lines expressing concern and availability of extra resources. Participants also provided feedback about a media prototype including a brand design and advertisement video for introducing the intervention. Conclusions This paper provides one model (including development of an engagement survey, audience for an engagement survey, methods for presenting results of an engagement survey) for including target users in the development of uptake strategies for online mental health interventions. PMID:24509475

User acceptance of intelligent avionics: A study of automatic-aided target recognition

NASA Technical Reports Server (NTRS)

Becker, Curtis A.; Hayes, Brian C.; Gorman, Patrick C.

1991-01-01

User acceptance of new support systems typically was evaluated after the systems were specified, designed, and built. The current study attempts to assess user acceptance of an Automatic-Aided Target Recognition (ATR) system using an emulation of such a proposed system. The detection accuracy and false alarm level of the ATR system were varied systematically, and subjects rated the tactical value of systems exhibiting different performance levels. Both detection accuracy and false alarm level affected the subjects' ratings. The data from two experiments suggest a cut-off point in ATR performance below which the subjects saw little tactical value in the system. An ATR system seems to have obvious tactical value only if it functions at a correct detection rate of 0.7 or better with a false alarm level of 0.167 false alarms per square degree or fewer.

CTF User's Manual

DOE Office of Scientific and Technical Information (OSTI.GOV)

Avramova, Maria; Blyth, Taylor S.; Salko, Robert K.

This document describes how to make a CTF input deck. A CTF input deck is organized into Card Groups and Cards. A Card Group is a collection of Cards. A Card is defined as a line of input. Each Card may contain multiple data. A Card is terminated by making a new line.

USER-FRIENDLY SOLAR OVENS FOR OUTDOOR AND INDOOR USE

EPA Science Inventory

Reduced memory skills and increased hair cortisol levels in recent Ecstasy/MDMA users: significant but independent neurocognitive and neurohormonal deficits.

PubMed

Downey, Luke A; Sands, Helen; Jones, Lewis; Clow, Angela; Evans, Phil; Stalder, Tobias; Parrott, Andrew C

2015-05-01

The goals of this study were to measure the neurocognitive performance of recent users of recreational Ecstasy and investigate whether it was associated with the stress hormone cortisol. The 101 participants included 27 recent light users of Ecstasy (one to four times in the last 3 months), 23 recent heavier Ecstasy users (five or more times) and 51 non-users. Rivermead paragraph recall provided an objective measure for immediate and delayed recall. The prospective and retrospective memory questionnaire provided a subjective index of memory deficits. Cortisol levels were taken from near-scalp 3-month hair samples. Cortisol was significantly raised in recent heavy Ecstasy users compared with controls, whereas hair cortisol in light Ecstasy users was not raised. Both Ecstasy groups were significantly impaired on the Rivermead delayed word recall, and both groups reported significantly more retrospective and prospective memory problems. Stepwise regression confirmed that lifetime Ecstasy predicted the extent of these memory deficits. Recreational Ecstasy is associated with increased levels of the bio-energetic stress hormone cortisol and significant memory impairments. No significant relationship between cortisol and the cognitive deficits was observed. Ecstasy users did display evidence of a metacognitive deficit, with the strength of the correlations between objective and subjective memory performances being significantly lower in the Ecstasy users. Copyright © 2015 John Wiley & Sons, Ltd.

Current and former marijuana use: preliminary findings of a longitudinal study of effects on IQ in young adults.

PubMed

Fried, Peter; Watkinson, Barbara; James, Deborah; Gray, Robert

2002-04-02

Assessing marijuana's impact on intelligence quotient (IQ) has been hampered by a lack of evaluation of subjects before they begin to use this substance. Using data from a group of young people whom we have been following since birth, we examined IQ scores before, during and after cessation of regular marijuana use to determine any impact of the drug on this measure of cognitive function. We determined marijuana use for seventy 17- to 20-year-olds through self-reporting and urinalysis. IQ difference scores were calculated by subtracting each person's IQ score at 9-12 years (before initiation of drug use) from his or her score at 17-20 years. We then compared the difference in IQ scores of current heavy users (at least 5 joints per week), current light users (less than 5 joints per week), former users (who had not smoked regularly for at least 3 months) and non-users (who never smoked more than once per week and no smoking in the past two weeks). Current marijuana use was significantly correlated (p < 0.05) in a dose-related fashion with a decline in IQ over the ages studied. The comparison of the IQ difference scores showed an average decrease of 4.1 points in current heavy users (p < 0.05) compared to gains in IQ points for light current users (5.8), former users (3.5) and non-users (2.6). Current marijuana use had a negative effect on global IQ score only in subjects who smoked 5 or more joints per week. A negative effect was not observed among subjects who had previously been heavy users but were no longer using the substance. We conclude that marijuana does not have a long-term negative impact on global intelligence. Whether the absence of a residual marijuana effect would also be evident in more specific cognitive domains such as memory and attention remains to be ascertained.

Evaluation of the user experience of "astronaut training device": an immersive, vr-based, motion-training system

NASA Astrophysics Data System (ADS)

Yue, Kang; Wang, Danli; Yang, Xinpan; Hu, Haichen; Liu, Yuqing; Zhu, Xiuqing

2016-10-01

To date, as the different application fields, most VR-based training systems have been different. Therefore, we should take the characteristics of application field into consideration and adopt different evaluation methods when evaluate the user experience of these training systems. In this paper, we propose a method to evaluate the user experience of virtual astronauts training system. Also, we design an experiment based on the proposed method. The proposed method takes learning performance as one of the evaluation dimensions, also combines with other evaluation dimensions such as: presence, immersion, pleasure, satisfaction and fatigue to evaluation user experience of the System. We collect subjective and objective data, the subjective data are mainly from questionnaire designed based on the evaluation dimensions and user interview conducted before and after the experiment. While the objective data are consisted of Electrocardiogram (ECG), reaction time, numbers of reaction error and the video data recorded during the experiment. For the analysis of data, we calculate the integrated score of each evaluation dimension by using factor analysis. In order to improve the credibility of the assessment, we use the ECG signal and reaction test data before and after experiment to validate the changes of fatigue during the experiment, and the typical behavioral features extracted from the experiment video to explain the result of subjective questionnaire. Experimental results show that the System has a better user experience and learning performance, but slight visual fatigue exists after experiment.

Comparative Analysis of Tear Film Levels of Inflammatory Mediators in Contact Lens Users.

PubMed

Yüksel Elgin, Cansu; İskeleli, Güzin; Talaz, Serap; Akyol, Sibel

2016-04-01

To compare tear films levels of various inflammatory cytokines in asymptomatic contact lens (CL) users. CL users of rigid gas-permeable CLs (RGPCL) (group 1) or silicone hydrogel CLs (SiHCL) (group 2) were compared with non-CL-using healthy subjects (group 3). Tear samples were collected from subjects in each group after ensuring that there were no complications secondary to CL wear in the CL-wearing participants. Tear-film levels of interleukins (ILs)-1β, -6, and -8; granulocyte-macrophage colony-stimulating factor (GM-CSF) (using the Luminex method); and leukotriene B4 (LTB4) (using the ELISA method) were determined. Cytokine levels were compared among the three groups using analysis-of-variance (ANOVA) and Kruskall-Wallis tests. There were significant differences in concentrations of IL-1β, GM-CSF and LTB4 among the three groups (p = 0.002, p = 0.021 and p = 0.009, respectively), as shown by the Kruskall-Wallis test comparing all three groups for the three cytokines. There were no significant differences for IL-6 and IL-8 (p = 0.079 and 0.094, respectively) when all three groups were compared. There were substantial statistically significant differences between RGPCL users, SiHCL users and control subjects in levels of tear film cytokines. Although CL users were asymptomatic, changes in tear-film levels of several important inflammatory mediators revealed that a chronic inflammatory process occurs during CL wear.

Xyce parallel electronic simulator : reference guide.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mei, Ting; Rankin, Eric Lamont; Thornquist, Heidi K.

2011-05-01

This document is a reference guide to the Xyce Parallel Electronic Simulator, and is a companion document to the Xyce Users Guide. The focus of this document is (to the extent possible) exhaustively list device parameters, solver options, parser options, and other usage details of Xyce. This document is not intended to be a tutorial. Users who are new to circuit simulation are better served by the Xyce Users Guide. The Xyce Parallel Electronic Simulator has been written to support, in a rigorous manner, the simulation needs of the Sandia National Laboratories electrical designers. It is targeted specifically to runmore » on large-scale parallel computing platforms but also runs well on a variety of architectures including single processor workstations. It also aims to support a variety of devices and models specific to Sandia needs. This document is intended to complement the Xyce Users Guide. It contains comprehensive, detailed information about a number of topics pertinent to the usage of Xyce. Included in this document is a netlist reference for the input-file commands and elements supported within Xyce; a command line reference, which describes the available command line arguments for Xyce; and quick-references for users of other circuit codes, such as Orcad's PSpice and Sandia's ChileSPICE.« less

Near-line Archive Data Mining at the Goddard Distributed Active Archive Center

NASA Astrophysics Data System (ADS)

Pham, L.; Mack, R.; Eng, E.; Lynnes, C.

2002-12-01

NASA's Earth Observing System (EOS) is generating immense volumes of data, in some cases too much to provide to users with data-intensive needs. As an alternative to moving the data to the user and his/her research algorithms, we are providing a means to move the algorithms to the data. The Near-line Archive Data Mining (NADM) system is the Goddard Earth Sciences Distributed Active Archive Center's (GES DAAC) web data mining portal to the EOS Data and Information System (EOSDIS) data pool, a 50-TB online disk cache. The NADM web portal enables registered users to submit and execute data mining algorithm codes on the data in the EOSDIS data pool. A web interface allows the user to access the NADM system. The users first develops personalized data mining code on their home platform and then uploads them to the NADM system. The C, FORTRAN and IDL languages are currently supported. The user developed code is automatically audited for any potential security problems before it is installed within the NADM system and made available to the user. Once the code has been installed the user is provided a test environment where he/she can test the execution of the software against data sets of the user's choosing. When the user is satisfied with the results, he/she can promote their code to the "operational" environment. From here the user can interactively run his/her code on the data available in the EOSDIS data pool. The user can also set up a processing subscription. The subscription will automatically process new data as it becomes available in the EOSDIS data pool. The generated mined data products are then made available for FTP pickup. The NADM system uses the GES DAAC-developed Simple Scalable Script-based Science Processor (S4P) to automate tasks and perform the actual data processing. Users will also have the option of selecting a DAAC-provided data mining algorithm and using it to process the data of their choice.

Learning to control an SSVEP-based BCI speller in naïve subjects.

PubMed

Zhihua Tang; Yijun Wang; Guoya Dong; Weihua Pei; Hongda Chen

2017-07-01

High-speed steady-state visual evoked potential (SSVEP)-based brain-computer interface (BCI) has been demonstrated in several recent studies. This study aimed to investigate some issues regarding feasibility of learning to control an SSVEP-based BCI speller in naïve subjects. An experiment with new BCI users was designed to answer the following questions: (1) How many people can use the SSVEP-BCI speller? (2) How much time is required to train the user? (3) Does continuous system use lead to user fatigue and deteriorated BCI performance? The experiment consisted of three tasks including a 40-class BCI spelling task, a psychomotor vigilance test (PVT) task, and a test of sleepiness scale. Subjects' reaction time (RT) in the PVT task and the fatigue rank in the sleepiness scale test were used as objective and subjective parameters to evaluate subjects' alertness level. Among 11 naïve subjects, 10 of them fulfilled the 9-block experiment. Four of them showed clear learning effects (i.e., an increasing trend of classification accuracy and information transfer rate (ITR)) over time. The remaining subjects showed stable BCI performance during the whole experiment. The results of RT and fatigue rank showed a gradually increasing trend, which is not significant across blocks. In summary, the results of this study suggest that controlling an SSVEP-based BCI speller is in general feasible to learn by naïve subjects after a short training procedure, showing no clear performance deterioration related to fatigue.

Using genetic algorithms with subjective input from human subjects: implications for fitting hearing aids and cochlear implants.

PubMed

Başkent, Deniz; Eiler, Cheryl L; Edwards, Brent

2007-06-01

To present a comprehensive analysis of the feasibility of genetic algorithms (GA) for finding the best fit of hearing aids or cochlear implants for individual users in clinical or research settings, where the algorithm is solely driven by subjective human input. Due to varying pathology, the best settings of an auditory device differ for each user. It is also likely that listening preferences vary at the same time. The settings of a device customized for a particular user can only be evaluated by the user. When optimization algorithms are used for fitting purposes, this situation poses a difficulty for a systematic and quantitative evaluation of the suitability of the fitting parameters produced by the algorithm. In the present study, an artificial listening environment was generated by distorting speech using a noiseband vocoder. The settings produced by the GA for this listening problem could objectively be evaluated by measuring speech recognition and comparing the performance to the best vocoder condition where speech was least distorted. Nine normal-hearing subjects participated in the study. The parameters to be optimized were the number of vocoder channels, the shift between the input frequency range and the synthesis frequency range, and the compression-expansion of the input frequency range over the synthesis frequency range. The subjects listened to pairs of sentences processed with the vocoder, and entered a preference for the sentence with better intelligibility. The GA modified the solutions iteratively according to the subject preferences. The program converged when the user ranked the same set of parameters as the best in three consecutive steps. The results produced by the GA were analyzed for quality by measuring speech intelligibility, for test-retest reliability by running the GA three times with each subject, and for convergence properties. Speech recognition scores averaged across subjects were similar for the best vocoder solution and for the solutions produced by the GA. The average number of iterations was 8 and the average convergence time was 25.5 minutes. The settings produced by different GA runs for the same subject were slightly different; however, speech recognition scores measured with these settings were similar. Individual data from subjects showed that in each run, a small number of GA solutions produced poorer speech intelligibility than for the best setting. This was probably a result of the combination of the inherent randomness of the GA, the convergence criterion used in the present study, and possible errors that the users might have made during the paired comparisons. On the other hand, the effect of these errors was probably small compared to the other two factors, as a comparison between subjective preferences and objective measures showed that for many subjects the two were in good agreement. The results showed that the GA was able to produce good solutions by using listener preferences in a relatively short time. For practical applications, the program can be made more robust by running the GA twice or by not using an automatic stopping criterion, and it can be made faster by optimizing the number of the paired comparisons completed in each iteration.

SIG. Signal Processing, Analysis, & Display

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hernandez, J.; Lager, D.; Azevedo, S.

1992-01-22

SIG is a general-purpose signal processing, analysis, and display program. Its main purpose is to perform manipulations on time and frequency-domain signals. However, it has been designed to ultimately accommodate other representations for data such as multiplexed signals and complex matrices. Two user interfaces are provided in SIG; a menu mode for the unfamiliar user and a command mode for more experienced users. In both modes errors are detected as early as possible and are indicated by friendly, meaningful messages. An on-line HELP package is also included. A variety of operations can be performed on time and frequency-domain signals includingmore » operations on the samples of a signal, operations on the entire signal, and operations on two or more signals. Signal processing operations that can be performed are digital filtering (median, Bessel, Butterworth, and Chebychev), ensemble average, resample, auto and cross spectral density, transfer function and impulse response, trend removal, convolution, Fourier transform and inverse window functions (Hamming, Kaiser-Bessel), simulation (ramp, sine, pulsetrain, random), and read/write signals. User definable signal processing algorithms are also featured. SIG has many options including multiple commands per line, command files with arguments, commenting lines, defining commands, and automatic execution for each item in a `repeat` sequence. Graphical operations on signals and spectra include: x-y plots of time signals; real, imaginary, magnitude, and phase plots of spectra; scaling of spectra for continuous or discrete domain; cursor zoom; families of curves; and multiple viewports.« less

SIG. Signal Processing, Analysis, & Display

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hernandez, J.; Lager, D.; Azevedo, S.

1992-01-22

SIG is a general-purpose signal processing, analysis, and display program. Its main purpose is to perform manipulations on time-and frequency-domain signals. However, it has been designed to ultimately accommodate other representations for data such as multiplexed signals and complex matrices. Two user interfaces are provided in SIG - a menu mode for the unfamiliar user and a command mode for more experienced users. In both modes errors are detected as early as possible and are indicated by friendly, meaningful messages. An on-line HELP package is also included. A variety of operations can be performed on time and frequency-domain signals includingmore » operations on the samples of a signal, operations on the entire signal, and operations on two or more signals. Signal processing operations that can be performed are digital filtering (median, Bessel, Butterworth, and Chebychev), ensemble average, resample, auto and cross spectral density, transfer function and impulse response, trend removal, convolution, Fourier transform and inverse window functions (Hamming, Kaiser-Bessel), simulation (ramp, sine, pulsetrain, random), and read/write signals. User definable signal processing algorithms are also featured. SIG has many options including multiple commands per line, command files with arguments, commenting lines, defining commands, and automatic execution for each item in a repeat sequence. Graphical operations on signals and spectra include: x-y plots of time signals; real, imaginary, magnitude, and phase plots of spectra; scaling of spectra for continuous or discrete domain; cursor zoom; families of curves; and multiple viewports.« less

Signal Processing, Analysis, & Display

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lager, Darrell; Azevado, Stephen

1986-06-01

SIG is a general-purpose signal processing, analysis, and display program. Its main purpose is to perform manipulations on time- and frequency-domain signals. However, it has been designed to ultimately accommodate other representations for data such as multiplexed signals and complex matrices. Two user interfaces are provided in SIG - a menu mode for the unfamiliar user and a command mode for more experienced users. In both modes errors are detected as early as possible and are indicated by friendly, meaningful messages. An on-line HELP package is also included. A variety of operations can be performed on time- and frequency-domain signalsmore » including operations on the samples of a signal, operations on the entire signal, and operations on two or more signals. Signal processing operations that can be performed are digital filtering (median, Bessel, Butterworth, and Chebychev), ensemble average, resample, auto and cross spectral density, transfer function and impulse response, trend removal, convolution, Fourier transform and inverse window functions (Hamming, Kaiser-Bessel), simulation (ramp, sine, pulsetrain, random), and read/write signals. User definable signal processing algorithms are also featured. SIG has many options including multiple commands per line, command files with arguments,commenting lines, defining commands, and automatic execution for each item in a repeat sequence. Graphical operations on signals and spectra include: x-y plots of time signals; real, imaginary, magnitude, and phase plots of spectra; scaling of spectra for continuous or discrete domain; cursor zoom; families of curves; and multiple viewports.« less

SIG. Signal Processing, Analysis, & Display

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hernandez, J.; Lager, D.; Azevedo, S.

1992-01-22

SIG is a general-purpose signal processing, analysis, and display program. Its main purpose is to perform manipulations on time- and frequency-domain signals. However, it has been designed to ultimately accommodate other representations for data such as multiplexed signals and complex matrices. Two user interfaces are provided in SIG - a menu mode for the unfamiliar user and a command mode for more experienced users. In both modes errors are detected as early as possible and are indicated by friendly, meaningful messages. An on-line HELP package is also included. A variety of operations can be performed on time- and frequency-domain signalsmore » including operations on the samples of a signal, operations on the entire signal, and operations on two or more signals. Signal processing operations that can be performed are digital filtering (median, Bessel, Butterworth, and Chebychev), ensemble average, resample, auto and cross spectral density, transfer function and impulse response, trend removal, convolution, Fourier transform and inverse window functions (Hamming, Kaiser-Bessel), simulation (ramp, sine, pulsetrain, random), and read/write signals. User definable signal processing algorithms are also featured. SIG has many options including multiple commands per line, command files with arguments,commenting lines, defining commands, and automatic execution for each item in a repeat sequence. Graphical operations on signals and spectra include: x-y plots of time signals; real, imaginary, magnitude, and phase plots of spectra; scaling of spectra for continuous or discrete domain; cursor zoom; families of curves; and multiple viewports.« less

First results concerning the safety, walking, and satisfaction with an innovative, microprocessor-controlled four-axes prosthetic foot.

PubMed

Hahn, Andreas; Sreckovic, Ivana; Reiter, Sebastian; Mileusnic, Milana

2018-06-01

The microprocessor-controlled foot Meridium is a prosthetic component with adjustable stance-phase characteristics. To investigate subjects' and prosthetists' perception of safety, walking, and satisfaction during first routine fittings. Multicenter, prospective, observational cohort study. Data regarding demographics, fitting process, safety, daily life activities, and satisfaction were obtained through questionnaires. The follow-up period was 7 months. In all, 89% of 70 users were satisfactorily fitted within the first two visits. Compared to previous feet, users reported improvements in walking on level ground (54% of subjects), uneven ground (82%), ascending (97%), and descending ramps (91%). More than 45% of the users perceived an improvement in safety and stability while standing and walking. No difference was observed in concentration, exertion, and pain. Overall user satisfaction with Meridium was 50% and the foot was preferred by 40% of users. Amputation level, age and mobility grade did not influence subjects' preference. Prosthetists recommended Meridium for 59% of subjects. A correlation analysis revealed that transfemoral amputees fitted with Genium and/or having a long residual limb strongly preferred Meridium ( p < 0.05). Meridium was appreciated by amputees with a preference for natural walking and requirement to safely and comfortably negotiate uneven terrain and slopes. Clinical relevance Amputees preferring Meridium perceive benefits with safe, comfortable, and natural walking. While the perception of benefits regarding the negotiation of uneven terrain and slopes is very high, the correlation to product preference is moderate. Individual assessment and trial fitting might be essential to identify patients who benefit greatly.

Vibrotactile grasping force and hand aperture feedback for myoelectric forearm prosthesis users.

PubMed

Witteveen, Heidi J B; Rietman, Hans S; Veltink, Peter H

2015-06-01

User feedback about grasping force and hand aperture is very important in object handling with myoelectric forearm prostheses but is lacking in current prostheses. Vibrotactile feedback increases the performance of healthy subjects in virtual grasping tasks, but no extensive validation on potential users has been performed. Investigate the performance of upper-limb loss subjects in grasping tasks with vibrotactile stimulation, providing hand aperture, and grasping force feedback. Cross-over trial. A total of 10 subjects with upper-limb loss performed virtual grasping tasks while perceiving vibrotactile feedback. Hand aperture feedback was provided through an array of coin motors and grasping force feedback through a single miniature stimulator or an array of coin motors. Objects with varying sizes and weights had to be grasped by a virtual hand. Percentages correctly applied hand apertures and correct grasping force levels were all higher for the vibrotactile feedback condition compared to the no-feedback condition. With visual feedback, the results were always better compared to the vibrotactile feedback condition. Task durations were comparable for all feedback conditions. Vibrotactile grasping force and hand aperture feedback improves grasping performance of subjects with upper-limb loss. However, it should be investigated whether this is of additional value in daily-life tasks. This study is a first step toward the implementation of sensory vibrotactile feedback for users of myoelectric forearm prostheses. Grasping force feedback is crucial for optimal object handling, and hand aperture feedback is essential for reduction of required visual attention. Grasping performance with feedback is evaluated for the potential users. © The International Society for Prosthetics and Orthotics 2014.

Multi-subject subspace alignment for non-stationary EEG-based emotion recognition.

PubMed

Chai, Xin; Wang, Qisong; Zhao, Yongping; Liu, Xin; Liu, Dan; Bai, Ou

2018-01-01

Emotion recognition based on EEG signals is a critical component in Human-Machine collaborative environments and psychiatric health diagnoses. However, EEG patterns have been found to vary across subjects due to user fatigue, different electrode placements, and varying impedances, etc. This problem renders the performance of EEG-based emotion recognition highly specific to subjects, requiring time-consuming individual calibration sessions to adapt an emotion recognition system to new subjects. Recently, domain adaptation (DA) strategies have achieved a great deal success in dealing with inter-subject adaptation. However, most of them can only adapt one subject to another subject, which limits their applicability in real-world scenarios. To alleviate this issue, a novel unsupervised DA strategy called Multi-Subject Subspace Alignment (MSSA) is proposed in this paper, which takes advantage of subspace alignment solution and multi-subject information in a unified framework to build personalized models without user-specific labeled data. Experiments on a public EEG dataset known as SEED verify the effectiveness and superiority of MSSA over other state of the art methods for dealing with multi-subject scenarios.

Effects of MDMA and Intranasal Oxytocin on Social and Emotional Processing

PubMed Central

Kirkpatrick, Matthew G; Lee, Royce; Wardle, Margaret C; Jacob, Suma; de Wit, Harriet

2014-01-01

MDMA (±3,4-methylenedioxymethamphetamine, ‘ecstasy') is used recreationally, reportedly because it increases feelings of empathy, sociability, and interpersonal closeness. One line of evidence suggests that MDMA produces these effects by releasing oxytocin, a peptide involved in social bonding. In the current study, we investigated the acute effects of MDMA and oxytocin on social and emotional processing in healthy human volunteers. MDMA users (N=65) participated in a 4-session, within-between-subjects study in which they received oral MDMA (0.75, 1.5 mg/kg), intranasal oxytocin (20 or 40 IU), or placebo under double-blind conditions. The primary outcomes included measures of emotion recognition and sociability (desire to be with others). Cardiovascular and subjective effects were also assessed. As expected, MDMA dose-dependently increased heart rate and blood pressure and feelings of euphoria (eg, ‘High' and ‘Like Drug'). On measures of social function, MDMA impaired recognition of angry and fearful facial expressions, and the larger dose (1.5 mg/kg) increased desire to be with others, compared with placebo. Oxytocin produced small but significant increases in feelings of sociability and enhanced recognition of sad facial expressions. Additionally, responses to oxytocin were related to responses to MDMA with subjects on two subjective measures of sociability. Thus, MDMA increased euphoria and feelings of sociability, perhaps by reducing sensitivity to subtle signs of negative emotions in others. The present findings provide only limited support for the idea that oxytocin produces the prosocial effects of MDMA. PMID:24448644

Influence of Social and Behavioural Characteristics of Users on Their Evaluation of Subjective Loudness and Acoustic Comfort in Shopping Malls

PubMed Central

Meng, Qi; Kang, Jian

2013-01-01

A large-scale subjective survey was conducted in six shopping malls in Harbin City, China, to determine the influence of social and behavioural characteristics of users on their evaluation of subjective loudness and acoustic comfort. The analysis of social characteristics shows that evaluation of subjective loudness is influenced by income and occupation, with correlation coefficients or contingency coefficients of 0.10 to 0.40 (p<0.05 or p<0.01). Meanwhile, evaluation of acoustic comfort evaluation is influenced by income, education level, and occupation, with correlation coefficients or contingency coefficients of 0.10 to 0.60 (p<0.05 or p<0.01). The effect of gender and age on evaluation of subjective loudness and acoustic comfort is statistically insignificant. The effects of occupation are mainly caused by the differences in income and education level, in which the effects of income are greater than that of education level. In terms of behavioural characteristics, evaluation of subjective loudness is influenced by the reason for visit, frequency of visit, and length of stay, with correlation coefficients or contingency coefficients of 0.10 to 0.40 (p<0.05 or p<0.01). Evaluation of acoustic comfort is influenced by the reason for visit to the site, the frequency of visit, length of stay, and also season of visit, with correlation coefficients of 0.10 to 0.30 (p<0.05 or p<0.01). In particular, users who are waiting for someone show lower evaluation of acoustic comfort, whereas users who go to shopping malls more than once a month show higher evaluation of acoustic comfort. On the contrary, the influence of the period of visit and the accompanying persons are found insignificant. PMID:23336003

On-Line Method and Apparatus for Coordinated Mobility and Manipulation of Mobile Robots

NASA Technical Reports Server (NTRS)

Seraji, Homayoun (Inventor)

1996-01-01

A simple and computationally efficient approach is disclosed for on-line coordinated control of mobile robots consisting of a manipulator arm mounted on a mobile base. The effect of base mobility on the end-effector manipulability index is discussed. The base mobility and arm manipulation degrees-of-freedom are treated equally as the joints of a kinematically redundant composite robot. The redundancy introduced by the mobile base is exploited to satisfy a set of user-defined additional tasks during the end-effector motion. A simple on-line control scheme is proposed which allows the user to assign weighting factors to individual degrees-of-mobility and degrees-of-manipulation, as well as to each task specification. The computational efficiency of the control algorithm makes it particularly suitable for real-time implementations. Four case studies are discussed in detail to demonstrate the application of the coordinated control scheme to various mobile robots.

Software-based measurement of thin filament lengths: an open-source GUI for Distributed Deconvolution analysis of fluorescence images

PubMed Central

Gokhin, David S.; Fowler, Velia M.

2016-01-01

The periodically arranged thin filaments within the striated myofibrils of skeletal and cardiac muscle have precisely regulated lengths, which can change in response to developmental adaptations, pathophysiological states, and genetic perturbations. We have developed a user-friendly, open-source ImageJ plugin that provides a graphical user interface (GUI) for super-resolution measurement of thin filament lengths by applying Distributed Deconvolution (DDecon) analysis to periodic line scans collected from fluorescence images. In the workflow presented here, we demonstrate thin filament length measurement using a phalloidin-stained cryosection of mouse skeletal muscle. The DDecon plugin is also capable of measuring distances of any periodically localized fluorescent signal from the Z- or M-line, as well as distances between successive Z- or M-lines, providing a broadly applicable tool for quantitative analysis of muscle cytoarchitecture. These functionalities can also be used to analyze periodic fluorescence signals in nonmuscle cells. PMID:27644080

Brain-computer interface controlled gaming: evaluation of usability by severely motor restricted end-users.

PubMed

Holz, Elisa Mira; Höhne, Johannes; Staiger-Sälzer, Pit; Tangermann, Michael; Kübler, Andrea

2013-10-01

Connect-Four, a new sensorimotor rhythm (SMR) based brain-computer interface (BCI) gaming application, was evaluated by four severely motor restricted end-users; two were in the locked-in state and had unreliable eye-movement. Following the user-centred approach, usability of the BCI prototype was evaluated in terms of effectiveness (accuracy), efficiency (information transfer rate (ITR) and subjective workload) and users' satisfaction. Online performance varied strongly across users and sessions (median accuracy (%) of end-users: A=.65; B=.60; C=.47; D=.77). Our results thus yielded low to medium effectiveness in three end-users and high effectiveness in one end-user. Consequently, ITR was low (0.05-1.44bits/min). Only two end-users were able to play the game in free-mode. Total workload was moderate but varied strongly across sessions. Main sources of workload were mental and temporal demand. Furthermore, frustration contributed to the subjective workload of two end-users. Nevertheless, most end-users accepted the BCI application well and rated satisfaction medium to high. Sources for dissatisfaction were (1) electrode gel and cap, (2) low effectiveness, (3) time-consuming adjustment and (4) not easy-to-use BCI equipment. All four end-users indicated ease of use as being one of the most important aspect of BCI. Effectiveness and efficiency are lower as compared to applications using the event-related potential as input channel. Nevertheless, the SMR-BCI application was satisfactorily accepted by the end-users and two of four could imagine using the BCI application in their daily life. Thus, despite moderate effectiveness and efficiency BCIs might be an option when controlling an application for entertainment. Copyright © 2013 Elsevier B.V. All rights reserved.

From Here to Obscurity?: Media Substitution Theory and Traditional Media in an On-Line World.

ERIC Educational Resources Information Center

Kaye, Barbara K.; Johnson, Thomas J.

2003-01-01

Describes an online survey targeted to politically interested users to assess whether traditional media use is decreasing, increasing, or remaining the same since users first started using the Web. Discusses media use gratifications, political attitudes, and demographics, and compares results with a similar study conducted in 1996. (Author/LRW)

47 CFR 63.17 - Special provisions for U.S. international common carriers.

Code of Federal Regulations, 2010 CFR

2010-10-01

... carrier, may interconnect its authorized private lines to the public switched network on behalf of an end user customer for the end user customer's own use. (b) Except as provided in paragraph (b)(4) of this...'s World Wide Web site at http://www.fcc.gov/ib. (3) Authorized carriers filing tariffs pursuant to...

47 CFR 63.17 - Special provisions for U.S. international common carriers.

Code of Federal Regulations, 2011 CFR

2011-10-01

... carrier, may interconnect its authorized private lines to the public switched network on behalf of an end user customer for the end user customer's own use. (b) Except as provided in paragraph (b)(4) of this...'s World Wide Web site at http://www.fcc.gov/ib. (3) Authorized carriers filing tariffs pursuant to...

47 CFR 63.17 - Special provisions for U.S. international common carriers.

Code of Federal Regulations, 2012 CFR

2012-10-01

... carrier, may interconnect its authorized private lines to the public switched network on behalf of an end user customer for the end user customer's own use. (b) Except as provided in paragraph (b)(4) of this...'s World Wide Web site at http://www.fcc.gov/ib. (3) Authorized carriers filing tariffs pursuant to...

Sole: Online Analysis of Southern FIA Data

Treesearch

Michael P. Spinney; Paul C. Van Deusen; Francis A. Roesch

2006-01-01

The Southern On Line Estimator (SOLE) is a flexible modular software program for analyzing U.S. Department of Agriculture Forest Service Forest Inventory and Analysis data. SOLE produces statistical tables, figures, maps, and portable document format reports based on user selected area and variables. SOLE?s Java-based graphical user interface is easy to use, and its R-...

Stan: A Probabilistic Programming Language for Bayesian Inference and Optimization

ERIC Educational Resources Information Center

Gelman, Andrew; Lee, Daniel; Guo, Jiqiang

2015-01-01

Stan is a free and open-source C++ program that performs Bayesian inference or optimization for arbitrary user-specified models and can be called from the command line, R, Python, Matlab, or Julia and has great promise for fitting large and complex statistical models in many areas of application. We discuss Stan from users' and developers'…

DESIGN PRINCIPLES FOR AN ON-LINE INFORMATION RETRIEVAL SYSTEM. TECHNICAL REPORT.

ERIC Educational Resources Information Center

LOWE, THOMAS C.

AREAS INVESTIGATED INCLUDE SLOW MEMORY DATA STORAGE, THE PROBLEM OF DECODING FROM AN INDEX TO A SLOW MEMORY ADDRESS, THE STRUCTURE OF DATA LISTS AND DATA LIST OPERATORS, COMMUNICATIONS BETWEEN THE HUMAN USER AND THE SYSTEM, PROCESSING OF RETRIEVAL REQUESTS, AND THE USER'S CONTROL OVER THE RETURN OF INFORMATION RETRIEVED. LINEAR, LINKED AND…

User-Based Information Retrieval System Interface Evaluation: An Examination of an On-Line Public Access Catalog.

ERIC Educational Resources Information Center

Hert, Carol A.; Nilan, Michael S.

1991-01-01

Presents preliminary data that characterizes the relationship between what users say they are trying to accomplish when using an online public access catalog (OPAC) and their perceptions of what input to give the system. Human-machine interaction is discussed, and appropriate methods for evaluating information retrieval systems are considered. (18…

Linking the pharmacological content of ecstasy tablets to the subjective experiences of drug users.

PubMed

Brunt, Tibor M; Koeter, Maarten W; Niesink, Raymond J M; van den Brink, Wim

2012-04-01

Most studies on the subjective effects of ecstasy are based on the assumption that the substance that was taken is 3,4-methylenedioxymethamphetamine (MDMA). However, many tablets sold as ecstasy contain other substances and MDMA in varying doses. So far, few attempts have been made to take this into account while assessing subjective effects. This study aims to link the pharmacological content of tablets sold as ecstasy to the subjective experiences reported by ecstasy users. Self-reported effects on ecstasy tablets were available from 5,786 drug users who handed in their tablets for chemical analysis at the Drug Information and Monitoring System (DIMS) in the Netherlands. Logistic regression was employed to link the pharmacological content of ecstasy tablets to the self-reported subjective effects and compare effects with MDMA to other substances present. MDMA showed a strong association with desirable subjective effects, unparalleled by any other psychoactive substance. However, the association of MDMA was dose-dependent, with higher doses (>120 mg/tablet) likely to evoke more adverse effects. The novel psychostimulants mephedrone and p-fluoroamphetamine were considered relatively desirable, whereas meta-chlorophenylpiperazine (mCPP) and p-methoxymethamphetamine (PMMA) were strongly associated with adverse subjective effects. Also, 3,4-methylene-dioxyamphetamine (MDA) and benzylpiperazine (BZP) were not appreciated as replacement for MDMA. Linking the pharmacological content of ecstasy sold on the street to subjective experiences contributes to a better understanding of the wide range of subjective effects ascribed to ecstasy and provides a strong rationale for the prolonged endurance of MDMA as the key ingredient of the ecstasy market.

Toward a hybrid brain-computer interface based on imagined movement and visual attention

NASA Astrophysics Data System (ADS)

Allison, B. Z.; Brunner, C.; Kaiser, V.; Müller-Putz, G. R.; Neuper, C.; Pfurtscheller, G.

2010-04-01

Brain-computer interface (BCI) systems do not work for all users. This article introduces a novel combination of tasks that could inspire BCI systems that are more accurate than conventional BCIs, especially for users who cannot attain accuracy adequate for effective communication. Subjects performed tasks typically used in two BCI approaches, namely event-related desynchronization (ERD) and steady state visual evoked potential (SSVEP), both individually and in a 'hybrid' condition that combines both tasks. Electroencephalographic (EEG) data were recorded across three conditions. Subjects imagined moving the left or right hand (ERD), focused on one of the two oscillating visual stimuli (SSVEP), and then simultaneously performed both tasks. Accuracy and subjective measures were assessed. Offline analyses suggested that half of the subjects did not produce brain patterns that could be accurately discriminated in response to at least one of the two tasks. If these subjects produced comparable EEG patterns when trying to use a BCI, these subjects would not be able to communicate effectively because the BCI would make too many errors. Results also showed that switching to a different task used in BCIs could improve accuracy in some of these users. Switching to a hybrid approach eliminated this problem completely, and subjects generally did not consider the hybrid condition more difficult. Results validate this hybrid approach and suggest that subjects who cannot use a BCI should consider switching to a different BCI approach, especially a hybrid BCI. Subjects proficient with both approaches might combine them to increase information throughput by improving accuracy, reducing selection time, and/or increasing the number of possible commands.

Training Aide: Research and Guidance for Effective Training User Guide

DTIC Science & Technology

2013-12-01

Research Product 2014-02 Training Aide: Research and Guidance for Effective Training User Guide Beth Plott Shaun...Effective Training User Guide 5a. CONTRACT OR GRANT NUMBER W91WAW-07-C-0081 5b. PROGRAM ELEMENT NUMBER 611102 6. AUTHOR(S) Beth Plott...Representative and Subject Matter POC: Karin A. Orvis 14. ABSTRACT: This is a user guide for the web-based tool called Training Aide: Research and Guidance

A comparative analysis of methamphetamine use: black gay and bisexual men in relation to men of other races.

PubMed

Halkitis, Perry N; Jerome, Roy C

2008-01-01

We investigated the patterns and correlates of methamphetamine use among Black gay and bisexual men who participated in a large-scale study of club drug use, and sexual behavior in combination with club drug use in New York City. Almost half of the Black men (49%) in the sample indicated use of methamphetamine in the 4 months prior to assessment, a proportion somewhat lower than their White counterparts. In terms of the overall sample, the proportion of the Black men in the study was equivalent to the proportion of methamphetamine users who identified as Black. Black methamphetamine users tended not to reside in neighborhoods considered traditionally gay, were more likely to be HIV-positive, have lower educational attainment, and have lower levels of income than other methamphetamine users. In terms of frequency and reasons for use, Black methamphetamine users did not differ in any substantive way compared to other races and ethnicities. In addition, they did not differ along any key demographic lines from Black non-methamphetamine users. Poly-drug use was common among all Black men in the sample, with almost all methamphetamine users also reporting use of cocaine, but cocaine users not necessarily reporting methamphetamine use. Once a drug that was considered popular only among White gay men, methamphetamine use has been shown to transcend racial and ethnic lines. Because of the synergy that exists between use of the drug, the concentrated levels of HIV in the Black gay population, and the sexual disinhibition engendered with methamphetamine use, this drug presents a potentially mounting public health challenge.

A Comparative Analysis of Methamphetamine Use: Black Gay and Bisexual Men in Relation to Men of Other Races

PubMed Central

Halkitis, Perry N.; Jerome, Roy C.

2009-01-01

We investigated the patterns and correlates of methamphetamine use among Black gay and bisexual men who participated in a large-scale study of club drug use, and sexual behavior in combination with club drug use in New York City. Almost half of the Black men (49%) in the sample indicated use of methamphetamine in the 4 months prior to assessment, a proportion somewhat lower than their White counterparts. In terms of the overall sample, the proportion of the Black men in the study was equivalent to the proportion of methamphetamine users who identified as Black. Black methamphetamine users tended not to reside in neighborhoods considered traditionally gay, were more likely to be HIV-positive, have lower educational attainment, and have lower levels of income than other methamphetamine users. In terms of frequency and reasons for use, Black methamphetamine users did not differ in any substantive way compared to other races and ethnicities. In addition, they did not differ along any key demographic lines from Black non-methamphetamine users. Poly-drug use was common among all Black men in the sample, with almost all methamphetamine users also reporting use of cocaine, but cocaine users not necessarily reporting methamphetamine use. Once a drug that was considered popular only among White gay men, methamphetamine use has been shown to transcend racial and ethnic lines. Because of the synergy that exists between use of the drug, the concentrated levels of HIV in the Black gay population, and the sexual disinhibition engendered with methamphetamine use, this drug presents a potentially mounting public health challenge. PMID:17825996

BpWrapper: BioPerl-based sequence and tree utilities for rapid prototyping of bioinformatics pipelines.

PubMed

Hernández, Yözen; Bernstein, Rocky; Pagan, Pedro; Vargas, Levy; McCaig, William; Ramrattan, Girish; Akther, Saymon; Larracuente, Amanda; Di, Lia; Vieira, Filipe G; Qiu, Wei-Gang

2018-03-02

Automated bioinformatics workflows are more robust, easier to maintain, and results more reproducible when built with command-line utilities than with custom-coded scripts. Command-line utilities further benefit by relieving bioinformatics developers to learn the use of, or to interact directly with, biological software libraries. There is however a lack of command-line utilities that leverage popular Open Source biological software toolkits such as BioPerl ( http://bioperl.org ) to make many of the well-designed, robust, and routinely used biological classes available for a wider base of end users. Designed as standard utilities for UNIX-family operating systems, BpWrapper makes functionality of some of the most popular BioPerl modules readily accessible on the command line to novice as well as to experienced bioinformatics practitioners. The initial release of BpWrapper includes four utilities with concise command-line user interfaces, bioseq, bioaln, biotree, and biopop, specialized for manipulation of molecular sequences, sequence alignments, phylogenetic trees, and DNA polymorphisms, respectively. Over a hundred methods are currently available as command-line options and new methods are easily incorporated. Performance of BpWrapper utilities lags that of precompiled utilities while equivalent to that of other utilities based on BioPerl. BpWrapper has been tested on BioPerl Release 1.6, Perl versions 5.10.1 to 5.25.10, and operating systems including Apple macOS, Microsoft Windows, and GNU/Linux. Release code is available from the Comprehensive Perl Archive Network (CPAN) at https://metacpan.org/pod/Bio::BPWrapper . Source code is available on GitHub at https://github.com/bioperl/p5-bpwrapper . BpWrapper improves on existing sequence utilities by following the design principles of Unix text utilities such including a concise user interface, extensive command-line options, and standard input/output for serialized operations. Further, dozens of novel methods for manipulation of sequences, alignments, and phylogenetic trees, unavailable in existing utilities (e.g., EMBOSS, Newick Utilities, and FAST), are provided. Bioinformaticians should find BpWrapper useful for rapid prototyping of workflows on the command-line without creating custom scripts for comparative genomics and other bioinformatics applications.

NASTRAN: Users' experiences

NASA Technical Reports Server (NTRS)

1973-01-01

The proceedings of a conference on NASA Structural Analysis (NASTRAN) to analyze the experiences of users of the program are presented. The subjects discussed include the following: (1) statics and buckling, (2) vibrations and dynamics, (3) substructing, (4) new capability, (5) user's experience, and (6) system experience. Specific applications of NASTRAN to spacecraft, aircraft, nuclear power plants, and materials tests are reported.

User Antennas

NASA Technical Reports Server (NTRS)

Jamnejad, Vahraz; Cramer, Paul

1990-01-01

The following subject areas are covered: (1) impact of frequency change of user and spacecraft antenna gain and size; (2) basic personal terminal antennas (impact of 20/30 GHz frequency separation; parametric studies - gain, size, weight; gain and figure of merit (G/T); design data for selected antenna concepts; critical technologies and development goals; and recommendations); and (3) user antenna radiation safety concerns.

What Friends Are For: Collaborative Intelligence Analysis and Search

DTIC Science & Technology

2014-06-01

14. SUBJECT TERMS Intelligence Community, information retrieval, recommender systems , search engines, social networks, user profiling, Lucene...improvements over existing search systems . The improvements are shown to be robust to high levels of human error and low similarity between users ...precision NOLH nearly orthogonal Latin hypercubes P@ precision at documents RS recommender systems TREC Text REtrieval Conference USM user

The effect of two different electronic health record user interfaces on intensive care provider task load, errors of cognition, and performance.

PubMed

Ahmed, Adil; Chandra, Subhash; Herasevich, Vitaly; Gajic, Ognjen; Pickering, Brian W

2011-07-01

The care of critically ill patients generates large quantities of data. Increasingly, these data are presented to the provider within an electronic medical record. The manner in which data are organized and presented can impact on the ability of users to synthesis that data into meaningful information. The objective of this study was to test the hypothesis that novel user interfaces, which prioritize the display of high-value data to providers within system-based packages, reduce task load, and result in fewer errors of cognition compared with established user interfaces that do not. Randomized crossover study. Academic tertiary referral center. Attending, resident and fellow critical care physicians. Novel health care record user interface. Subjects randomly assigned to either a standard electronic medical record or a novel user interface, were asked to perform a structured task. The task required the subjects to use the assigned electronic environment to review the medical record of an intensive care unit patient said to be actively bleeding for data that formed the basis of answers to clinical questions posed in the form of a structured questionnaire. The primary outcome was task load, measured using the paper version of the NASA-task load index. Secondary outcome measures included time to task completion, number of errors of cognition measured by comparison of subject to post hoc gold standard questionnaire responses, and the quantity of information presented to subjects by each environment. Twenty subjects completed the task on eight patients, resulting in 160 patient-provider encounters (80 in each group). The standard electronic medical record contained a much larger data volume with a median (interquartile range) number of data points per patient of 1008 (895-1183) compared with 102 (77-112) contained within the novel user interface. The median (interquartile range) NASA-task load index values were 38.8 (32-45) and 58 (45-65) for the novel user interface compared with the standard electronic medical record (p < .001). The median (interquartile range) times in seconds taken to complete the task for four consecutive patients were 93 (57-132), 60 (48-71), 68 (48-80), and 54 (42-64) for the novel user interface compared with 145 (109-201), 125 (113-162), 129 (100-145), and 112 (92-123) for the standard interface (p < .0001), respectively. The median (interquartile range) number of errors per provider was 0.5 (0-1) and two (0.25-3) for the novel user interface and standard electronic medical record interface, respectively (p = .007). A novel user interface was designed based on the information needs of intensive care unit providers with a specific goal of development being the reduction of task load and errors of cognition associated with filtering, extracting, and using medical data contained within a comprehensive electronic medical record. The results of this simulated clinical experiment suggest that the configuration of the intensive care unit user interface contributes significantly to the task load, time to task completion, and number of errors of cognition associated with the identification, and subsequent use, of relevant patient data. Task-specific user interfaces, developed from an understanding of provider information requirements, offer advantages over interfaces currently available within a standard electronic medical record.

Adaptive Motor Resistance Video Game Exercise Apparatus and Method of Use Thereof

NASA Technical Reports Server (NTRS)

Reich, Alton (Inventor); Shaw, James (Inventor)

2015-01-01

The invention comprises a method and/or an apparatus using computer configured exercise equipment and an electric motor provided physical resistance in conjunction with a game system, such as a video game system, where the exercise system provides real physical resistance to a user interface. Results of user interaction with the user interface are integrated into a video game, such as running on a game console. The resistance system comprises: a subject interface, software control, a controller, an electric servo assist/resist motor, an actuator, and/or a subject sensor. The system provides actual physical interaction with a resistance device as input to the game console and game run thereon.

Preliminary Results of an Examination of Electronic Cigarette User Puff Topography: The Effect of a Mouthpiece-Based Topography Measurement Device on Plasma Nicotine and Subjective Effects

PubMed Central

Spindle, Tory R.; Breland, Alison B.; Karaoghlanian, Nareg V.; Shihadeh, Alan L.

2015-01-01

Introduction: Electronic cigarettes (ECIGs) heat a nicotine-containing solution; the resulting aerosol is inhaled by the user. Nicotine delivery may be affected by users’ puffing behavior (puff topography), and little is known about the puff topography of ECIG users. Puff topography can be measured using mouthpiece-based computerized systems. However, the extent to which a mouthpiece influences nicotine delivery and subjective effects in ECIG users is unknown. Methods: Plasma nicotine concentration, heart rate, and subjective effects were measured in 13 experienced ECIG users who used their preferred ECIG and liquid (≥12mg/ml nicotine) during 2 sessions (with or without a mouthpiece). In both sessions, participants completed an ECIG use session in which they were instructed to take 10 puffs with 30-second inter-puff intervals. Puff topography was recorded in the mouthpiece condition. Results: Almost all measures of the effects of ECIG use were independent of topography measurement. Collapsed across session, mean plasma nicotine concentration increased by 16.8ng/ml, and mean heart rate increased by 8.5 bpm (ps < .05). Withdrawal symptoms decreased significantly after ECIG use. Participants reported that the mouthpiece affected awareness and made ECIG use more difficult. Relative to previously reported data for tobacco cigarette smokers using similar topography measurement equipment, ECIG-using participants took larger and longer puffs with lower flow rates. Conclusions: In experienced ECIG users, measuring ECIG topography did not influence ECIG-associated nicotine delivery or most measures of withdrawal suppression. Topography measurement systems will need to account for the low flow rates observed for ECIG users. PMID:25239957

Decreased frontal lobe phosphocreatine levels in methamphetamine users

PubMed Central

Sung, Young-Hoon; Yurgelun-Todd, Deborah A.; Shi, Xian-Feng; Kondo, Douglas G.; Lundberg, Kelly J.; McGlade, Erin C.; Hellem, Tracy L.; Huber, Rebekah S.; Fiedler, Kristen K.; Harrell, Renee E.; Nickerson, Bethany R.; Kim, Seong-Eun; Jeong, Eun-Kee; Renshaw, Perry F.

2012-01-01

BACKGROUND Mitochondria-related mechanisms have been suggested to mediate methamphetamine (METH) toxicity. However, changes in brain energetics associated with highenergy phosphate metabolism have not been investigated in METH users. Phosphorus-31 (31P) magnetic resonance spectroscopy (MRS) was used to evaluate changes in mitochondrial high energy phosphates, including phosphocreatine (PCr) and β-nucleoside triphosphate (β-NTP, primarily ATP in brain) levels. We hypothesized that METH users would have decreased high-energy PCr levels in the frontal gray matter. METHODS Study participants consisted of 51 METH (age=32.8±6.7) and 23 healthy comparison (age=31.1±7.5) subjects. High-energy phosphate metabolite levels were compared between the groups and potential gender differences were explored. RESULTS METH users had lower ratios of PCr to total pool of exchangeable phosphate (PCr/TPP) in the frontal lobe as compared to the healthy subjects (p=0.001). The lower PCr levels in METH subjects were significantly associated with lifetime amount of METH use (p=0.003). A sub-analysis for gender differences revealed that female METH users, who had lower daily amounts (1.1±1.0 gram) of METH use than males (1.4±1.7 gram), had significantly lower PCr/TPP ratios than male METH users, controlling for the amount of METH use (p=0.02). CONCLUSIONS The present findings suggest that METH compromises frontal lobe high-energy phosphate metabolism in a dose-responsive manner. Our findings also suggest that the abnormality in frontal lobe high-energy phosphate metabolism might be more prominent in female than in male METH users. This is significant as decreased PCr levels have been associated with depressive symptoms, and poor responses to antidepressant treatment have been reported in those with decreased PCr levels. PMID:23084413

Automatic user customization for improving the performance of a self-paced brain interface system.

PubMed

Fatourechi, Mehrdad; Bashashati, Ali; Birch, Gary E; Ward, Rabab K

2006-12-01

Customizing the parameter values of brain interface (BI) systems by a human expert has the advantage of being fast and computationally efficient. However, as the number of users and EEG channels grows, this process becomes increasingly time consuming and exhausting. Manual customization also introduces inaccuracies in the estimation of the parameter values. In this paper, the performance of a self-paced BI system whose design parameter values were automatically user customized using a genetic algorithm (GA) is studied. The GA automatically estimates the shapes of movement-related potentials (MRPs), whose features are then extracted to drive the BI. Offline analysis of the data of eight subjects revealed that automatic user customization improved the true positive (TP) rate of the system by an average of 6.68% over that whose customization was carried out by a human expert, i.e., by visually inspecting the MRP templates. On average, the best improvement in the TP rate (an average of 9.82%) was achieved for four individuals with spinal cord injury. In this case, the visual estimation of the parameter values of the MRP templates was very difficult because of the highly noisy nature of the EEG signals. For four able-bodied subjects, for which the MRP templates were less noisy, the automatic user customization led to an average improvement of 3.58% in the TP rate. The results also show that the inter-subject variability of the TP rate is also reduced compared to the case when user customization is carried out by a human expert. These findings provide some primary evidence that automatic user customization leads to beneficial results in the design of a self-paced BI for individuals with spinal cord injury.

Residual cannabis levels in blood, urine and oral fluid following heavy cannabis use.

PubMed

Odell, Morris S; Frei, Matthew Y; Gerostamoulos, Dimitri; Chu, Mark; Lubman, Dan I

2015-04-01

An understanding of tetrahydrocannabinol (THC) kinetics and residual levels after cannabis use is essential in interpreting toxicology tests in body fluids from live subjects, particularly when used in forensic settings for drug abuse, traffic and interpersonal violence cases. However the current literature is largely based on laboratory studies using controlled cannabis dosages in experienced users, with limited research investigating the kinetics of residual THC concentrations in regular high dose cannabis users. Twenty-one dependent cannabis users were recruited at admission to two residential detoxification units in Melbourne, Australia. After being provided with information about, and consenting to, the study, subjects volunteered to provide once-daily blood, urine and oral fluid (saliva) samples for seven consecutive days following admission, involving cessation and abstinence from all cannabis use. Blood and oral fluid specimens were analysed for THC and urine specimens for the metabolite THC-COOH. In some subjects THC was detectable in blood for at least 7 days and oral fluid specimens were positive for THC up to 78 h after admission to the unit. Urinary THC-COOH concentrations exceeded 1000 ng/mL for some subjects 129 h after last use. The presented blood THC levels are higher and persist longer in some individuals than previously described, our understanding and interpretation of THC levels in long term heavy cannabis users may need to be reconsidered. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

A Wearable Home BCI system: preliminary results with SSVEP protocol.

PubMed

Piccini, Luca; Parini, Sergio; Maggi, Luca; Andreoni, Giuseppe

2005-01-01

This paper presents and discusses the realization and the performances of a wearable system for EEG-based BCI applications. The system (called Kimera) consists of a two-layer hardware architecture (the wireless acquisition and transmission board based on a Bluetooth ® ARM chip, and a low power miniaturized biosignal acquisition analog front end) together with a software suite (called Bellerophonte) for the Graphic User Interface management, protocol execution, data recording, transmission and processing. The implemented BCI system was based on the SSVEP protocol, applied to a two state selection by using standards display/monitor with a couple of high efficiency LEDs. The frequency features of the signal were computed and used in the intention detection. The BCI algorithm is based on a supervised classifier implemented through a multi-class Canonical Discriminant Analysis (CDA) with a continuous realtime feedback based on the mahalanobis distance parameter. Five healthy subjects participated in the first phase for a preliminary device validation. The obtained results are very interesting and promising, being lined out to the most recent performance reported in literature with a significant improvement both in system and in classification capabilities. The user-friendliness and low cost of the Kimera& Bellerophonte platform make it suitable for the development of home BCI applications.

Memorabeatlia: a naturalistic study of long-term memory.

PubMed

Hyman, I E; Rubin, D C

1990-03-01

Seventy-six undergraduates were given the titles and first lines of Beatles' songs and asked to recall the songs. Seven hundred and four different undergraduates were cued with one line from each of 25 Beatles' songs and asked to recall the title. The probability of recalling a line was best predicted by the number of times a line was repeated in the song and how early the line first appeared in the song. The probability of cuing to the title was best predicted by whether the line shared words with the title. Although the subjects recalled only 21% of the lines, there were very few errors in recall, and the errors rarely violated the rhythmic, poetic, or thematic constraints of the songs. Acting together, these constraints can account for the near verbatim recall observed. Fourteen subjects, who transcribed one song, made fewer and different errors than the subjects who had recalled the song, indicating that the errors in recall were not primarily the result of errors in encoding.

[Emotional response to music by postlingually-deafened adult cochlear implant users].

PubMed

Wang, Shuo; Dong, Ruijuan; Zhou, Yun; Li, Jing; Qi, Beier; Liu, Bo

2012-10-01

To assess the emotional response to music by postlingually-deafened adult cochlear implant users. Munich music questionnaire (MUMU) was used to match the music experience and the motivation of use of music between 12 normal-hearing and 12 cochlear implant subjects. Emotion rating test in Musical Sounds in Cochlear Implants (MuSIC) test battery was used to assess the emotion perception ability for both normal-hearing and cochlear implant subjects. A total of 15 pieces of music phases were used. Responses were given by selecting the rating scales from 1 to 10. "1" represents "very sad" feeling, and "10" represents "very happy feeling. In comparison with normal-hearing subjects, 12 cochlear implant subjects made less active use of music for emotional purpose. The emotion ratings for cochlear implant subjects were similar to normal-hearing subjects, but with large variability. Post-lingually deafened cochlear implant subjects on average performed similarly in emotion rating tasks relative to normal-hearing subjects, but their active use of music for emotional purpose was obviously less than normal-hearing subjects.

Processing of speech temporal and spectral information by users of auditory brainstem implants and cochlear implants.

PubMed

Azadpour, Mahan; McKay, Colette M

2014-01-01

Auditory brainstem implants (ABI) use the same processing strategy as was developed for cochlear implants (CI). However, the cochlear nucleus (CN), the stimulation site of ABIs, is anatomically and physiologically more complex than the auditory nerve and consists of neurons with differing roles in auditory processing. The aim of this study was to evaluate the hypotheses that ABI users are less able than CI users to access speech spectro-temporal information delivered by the existing strategies and that the sites stimulated by different locations of CI and ABI electrode arrays differ in encoding of temporal patterns in the stimulation. Six CI users and four ABI users of Nucleus implants with ACE processing strategy participated in this study. Closed-set perception of aCa syllables (16 consonants) and bVd words (11 vowels) was evaluated via experimental processing strategies that activated one, two, or four of the electrodes of the array in a CIS manner as well as subjects' clinical strategies. Three single-channel strategies presented the overall temporal envelope variations of the signal on a single-implant electrode located at the high-, medium-, and low-frequency regions of the array. Implantees' ability to discriminate within electrode temporal patterns of stimulation for phoneme perception and their ability to make use of spectral information presented by increased number of active electrodes were assessed in the single- and multiple-channel strategies, respectively. Overall percentages and information transmission of phonetic features were obtained for each experimental program. Phoneme perception performance of three ABI users was within the range of CI users in most of the experimental strategies and improved as the number of active electrodes increased. One ABI user performed close to chance with all the single and multiple electrode strategies. There was no significant difference between apical, basal, and middle CI electrodes in transmitting speech temporal information, except a trend that the voicing feature was the least transmitted by the basal electrode. A similar electrode-location pattern could be observed in most ABI subjects. Although the number of tested ABI subjects was small, their wide range of phoneme perception performance was consistent with previous reports of overall speech perception in ABI patients. The better-performing ABI user participants had access to speech temporal and spectral information that was comparable to that of average CI user. The poor-performing ABI user did not have access to within-channel speech temporal information and did not benefit from an increased number of spectral channels. The within-subject variability between different ABI electrodes was less than the variability across users in transmission of speech temporal information. The difference in the performance of ABI users could be related to the location of their electrode array on the CN, anatomy, and physiology of their CN or the damage to their auditory brainstem due to tumor or surgery.

Design and development of an automated, portable and handheld tablet personal computer-based data acquisition system for monitoring electromyography signals during rehabilitation.

PubMed

Ahamed, Nizam U; Sundaraj, Kenneth; Poo, Tarn S

2013-03-01

This article describes the design of a robust, inexpensive, easy-to-use, small, and portable online electromyography acquisition system for monitoring electromyography signals during rehabilitation. This single-channel (one-muscle) system was connected via the universal serial bus port to a programmable Windows operating system handheld tablet personal computer for storage and analysis of the data by the end user. The raw electromyography signals were amplified in order to convert them to an observable scale. The inherent noise of 50 Hz (Malaysia) from power lines electromagnetic interference was then eliminated using a single-hybrid IC notch filter. These signals were sampled by a signal processing module and converted into 24-bit digital data. An algorithm was developed and programmed to transmit the digital data to the computer, where it was reassembled and displayed in the computer using software. Finally, the following device was furnished with the graphical user interface to display the online muscle strength streaming signal in a handheld tablet personal computer. This battery-operated system was tested on the biceps brachii muscles of 20 healthy subjects, and the results were compared to those obtained with a commercial single-channel (one-muscle) electromyography acquisition system. The results obtained using the developed device when compared to those obtained from a commercially available physiological signal monitoring system for activities involving muscle contractions were found to be comparable (the comparison of various statistical parameters) between male and female subjects. In addition, the key advantage of this developed system over the conventional desktop personal computer-based acquisition systems is its portability due to the use of a tablet personal computer in which the results are accessible graphically as well as stored in text (comma-separated value) form.

Remote Data Exploration with the Interactive Data Language (IDL)

NASA Technical Reports Server (NTRS)

Galloy, Michael

2013-01-01

A difficulty for many NASA researchers is that often the data to analyze is located remotely from the scientist and the data is too large to transfer for local analysis. Researchers have developed the Data Access Protocol (DAP) for accessing remote data. Presently one can use DAP from within IDL, but the IDL-DAP interface is both limited and cumbersome. A more powerful and user-friendly interface to DAP for IDL has been developed. Users are able to browse remote data sets graphically, select partial data to retrieve, import that data and make customized plots, and have an interactive IDL command line session simultaneous with the remote visualization. All of these IDL-DAP tools are usable easily and seamlessly for any IDL user. IDL and DAP are both widely used in science, but were not easily used together. The IDL DAP bindings were incomplete and had numerous bugs that prevented their serious use. For example, the existing bindings did not read DAP Grid data, which is the organization of nearly all NASA datasets currently served via DAP. This project uniquely provides a fully featured, user-friendly interface to DAP from IDL, both from the command line and a GUI application. The DAP Explorer GUI application makes browsing a dataset more user-friendly, while also providing the capability to run user-defined functions on specified data. Methods for running remote functions on the DAP server were investigated, and a technique for accomplishing this task was decided upon.

Assessment of the Speech Intelligibility Performance of Post Lingual Cochlear Implant Users at Different Signal-to-Noise Ratios Using the Turkish Matrix Test.

PubMed

Polat, Zahra; Bulut, Erdoğan; Ataş, Ahmet

2016-09-01

Spoken word recognition and speech perception tests in quiet are being used as a routine in assessment of the benefit which children and adult cochlear implant users receive from their devices. Cochlear implant users generally demonstrate high level performances in these test materials as they are able to achieve high level speech perception ability in quiet situations. Although these test materials provide valuable information regarding Cochlear Implant (CI) users' performances in optimal listening conditions, they do not give realistic information regarding performances in adverse listening conditions, which is the case in the everyday environment. The aim of this study was to assess the speech intelligibility performance of post lingual CI users in the presence of noise at different signal-to-noise ratio with the Matrix Test developed for Turkish language. Cross-sectional study. The thirty post lingual implant user adult subjects, who had been using implants for a minimum of one year, were evaluated with Turkish Matrix test. Subjects' speech intelligibility was measured using the adaptive and non-adaptive Matrix Test in quiet and noisy environments. The results of the study show a correlation between Pure Tone Average (PTA) values of the subjects and Matrix test Speech Reception Threshold (SRT) values in the quiet. Hence, it is possible to asses PTA values of CI users using the Matrix Test also. However, no correlations were found between Matrix SRT values in the quiet and Matrix SRT values in noise. Similarly, the correlation between PTA values and intelligibility scores in noise was also not significant. Therefore, it may not be possible to assess the intelligibility performance of CI users using test batteries performed in quiet conditions. The Matrix Test can be used to assess the benefit of CI users from their systems in everyday life, since it is possible to perform intelligibility test with the Matrix test using a material that CI users experience in their everyday life and it is possible to assess their difficulty in speech discrimination in noisy conditions they have to cope with.

Fluorescent proteins for quantitative microscopy: important properties and practical evaluation.

PubMed

Shaner, Nathan Christopher

2014-01-01

More than 20 years after their discovery, fluorescent proteins (FPs) continue to be the subject of massive engineering efforts yielding continued improvements. Among these efforts are many aspects that should be of great interest to quantitative imaging users. With new variants frequently introduced into the research community, "tried and true" FPs that have been relied on for many years may now be due for upgrades to more modern variants. However, the dizzying array of FPs now available can make the initial act of narrowing down the potential choices an intimidating prospect. This chapter describes the FP properties that most strongly impact their performance in quantitative imaging experiments, along with their physical origins as they are currently understood. A workflow for evaluating a given FP in the researcher's chosen experimental system (e.g., a specific cell line) is described. © 2014 Elsevier Inc. All rights reserved.

Engineering studies of vectorcardiographs in blood pressure measuring systems, appendix 3

NASA Technical Reports Server (NTRS)

Mark, R. G.

1975-01-01

The following subjects were covered: (1) ASM80 manual, (2) signal preprocessing as an aid to on-line EKG analysis, and (3) high speed evaluation of magnetic tape recordings of electrocardiograms. A description of the ASM80 symbolic assembly program for the INTEL 8080 microprocessor and a user's manual were presented. The capability of three redundancy reduction algorithms to produce adequate representations of electrocardiographic data was examined. A hardware device was constructed which carried out zero order interpolation on a signal. Examination of the zero order interpolators reconstructed signal indicated that this representation was adequate for analysis of rhythm. A system to analyze magnetic tapes of electrocardiograms recorded over 24 hour intervals was designed. The recordings are sampled 200 times per second using a Nova computer and a special interface system. This system was tested on several recordings of clinical data, containing over 75 premature ventricular contractions, each one of which was flagged.

Building VoiceXML-Based Applications

DTIC Science & Technology

2002-01-01

basketball games. The Busline systems were pri- y developed using an early implementation of VoiceXML he NBA Update Line was developed using VoiceXML...traveling in and out of Pittsburgh’s rsity neighborhood. The second project is the NBA Up- Line, which provides callers with real-time information NBA ... NBA UPDATE LINE The target user of this system is a fairly knowledgeable basket- ball fan; the system must therefore be able to provide detailed

ASERA: A Spectrum Eye Recognition Assistant

NASA Astrophysics Data System (ADS)

Yuan, Hailong; Zhang, Haotong; Zhang, Yanxia; Lei, Yajuan; Dong, Yiqiao; Zhao, Yongheng

2018-04-01

ASERA, ASpectrum Eye Recognition Assistant, aids in quasar spectral recognition and redshift measurement and can also be used to recognize various types of spectra of stars, galaxies and AGNs (Active Galactic Nucleus). This interactive software allows users to visualize observed spectra, superimpose template spectra from the Sloan Digital Sky Survey (SDSS), and interactively access related spectral line information. ASERA is an efficient and user-friendly semi-automated toolkit for the accurate classification of spectra observed by LAMOST (the Large Sky Area Multi-object Fiber Spectroscopic Telescope) and is available as a standalone Java application and as a Java applet. The software offers several functions, including wavelength and flux scale settings, zoom in and out, redshift estimation, and spectral line identification.

A mathematical model for Vertical Attitude Takeoff and Landing (VATOL) aircraft simulation. Volume 3: User's manual for VATOL simulation program

NASA Technical Reports Server (NTRS)

Fortenbaugh, R. L.

1980-01-01

Instructions for using Vertical Attitude Takeoff and Landing Aircraft Simulation (VATLAS), the digital simulation program for application to vertical attitude takeoff and landing (VATOL) aircraft developed for installation on the NASA Ames CDC 7600 computer system are described. The framework for VATLAS is the Off-Line Simulation (OLSIM) routine. The OLSIM routine provides a flexible framework and standardized modules which facilitate the development of off-line aircraft simulations. OLSIM runs under the control of VTOLTH, the main program, which calls the proper modules for executing user specified options. These options include trim, stability derivative calculation, time history generation, and various input-output options.

Gromita: a fully integrated graphical user interface to gromacs 4.

PubMed

Sellis, Diamantis; Vlachakis, Dimitrios; Vlassi, Metaxia

2009-09-07

Gromita is a fully integrated and efficient graphical user interface (GUI) to the recently updated molecular dynamics suite Gromacs, version 4. Gromita is a cross-platform, perl/tcl-tk based, interactive front end designed to break the command line barrier and introduce a new user-friendly environment to run molecular dynamics simulations through Gromacs. Our GUI features a novel workflow interface that guides the user through each logical step of the molecular dynamics setup process, making it accessible to both advanced and novice users. This tool provides a seamless interface to the Gromacs package, while providing enhanced functionality by speeding up and simplifying the task of setting up molecular dynamics simulations of biological systems. Gromita can be freely downloaded from http://bio.demokritos.gr/gromita/.

Increased Incidence of Visual Field Abnormalities as Determined by Frequency Doubling Technology Perimetry in High Computer Users Among Japanese Workers: A Retrospective Cohort Study.

PubMed

Nakano, Tadashi; Hayashi, Takeshi; Nakagawa, Toru; Honda, Toru; Owada, Satoshi; Endo, Hitoshi; Tatemichi, Masayuki

2018-04-05

This retrospective cohort study primarily aimed to investigate the possible association of computer use with visual field abnormalities (VFA) among Japanese workers. The study included 2,377 workers (mean age 45.7 [standard deviation, 8.3] years; 2,229 men and 148 women) who initially exhibited no VFA during frequency doubling technology perimetry (FDT) testing. Subjects then underwent annual follow-up FDT testing for 7 years, and VFA were determined using a FDT-test protocol (FDT-VFA). Subjects with FDT-VFA were examined by ophthalmologists. Baseline data about the mean duration of computer use during a 5-year period and refractive errors were obtained via self-administered questionnaire and evaluations for refractive errors (use of eyeglasses or contact lenses), respectively. A Cox proportional hazard analysis demonstrated that heavy computer users (>8 hr/day) had a significantly increased risk of FDT-VFA (hazard ratio [HR] 2.85; 95% confidence interval [CI], 1.26-6.48) relative to light users (<4 hr/day), and this association was strengthened among subjects with refractive errors (HR 4.48; 95% CI, 1.87-10.74). The computer usage history also significantly correlated with FDT-VFA among subject with refractive errors (P < 0.05), and 73.1% of subjects with FDT-VFA and refractive errors were diagnosed with glaucoma or ocular hypertension. The incidence of FDT-VFA appears to be increased among Japanese workers who are heavy computer users, particularly if they have refractive errors. Further investigations of epidemiology and causality are warranted.

WMI2, the Student's On-Line Symbolic Calculator

ERIC Educational Resources Information Center

Kovacs, Zoltan

2011-01-01

Student activities focused on discovering mathematics play an important role in the teaching and learning process. WebMathematics Interactive (WMI2) was developed to offer a fast and user-friendly on-line web interface to enhance the quality of both theoretical and applied mathematics courses. For the teacher, in the classroom, it provides…

An On-Line Program for Intermediate Level Latin Readings.

ERIC Educational Resources Information Center

Raia, Ann

2001-01-01

Introduces an on-line intermediate Latin program to potential users by describing the goals and elements of the site (www.iona.edu/latin). Operation of the program is described, as well as the benefits for language education, its current uses, and suggestions for more creative uses in the classroom. (Author/VWL)

External Labeling as a Framework for Access Control

ERIC Educational Resources Information Center

Rozenbroek, Thomas H.

2012-01-01

With the ever increasing volume of data existing on and passing through on-line resources together with a growing number of legitimate users of that information and potential adversaries, the need for better security and safeguards is immediate and critical. Currently, most of the security and safeguards afforded on-line information are provided…

The clinical relevance of advanced artificial feedback in the control of a multi-functional myoelectric prosthesis.

PubMed

Markovic, Marko; Schweisfurth, Meike A; Engels, Leonard F; Bentz, Tashina; Wüstefeld, Daniela; Farina, Dario; Dosen, Strahinja

2018-03-27

To effectively replace the human hand, a prosthesis should seamlessly respond to user intentions but also convey sensory information back to the user. Restoration of sensory feedback is rated highly by the prosthesis users, and feedback is critical for grasping in able-bodied subjects. Nonetheless, the benefits of feedback in prosthetics are still debated. The lack of consensus is likely due to the complex nature of sensory feedback during prosthesis control, so that its effectiveness depends on multiple factors (e.g., task complexity, user learning). We evaluated the impact of these factors with a longitudinal assessment in six amputee subjects, using a clinical setup (socket, embedded control) and a range of tasks (box and blocks, block turn, clothespin and cups relocation). To provide feedback, we have proposed a novel vibrotactile stimulation scheme capable of transmitting multiple variables from a multifunction prosthesis. The subjects wore a bracelet with four by two uniformly placed vibro-tactors providing information on contact, prosthesis state (active function), and grasping force. The subjects also completed a questionnaire for the subjective evaluation of the feedback. The tests demonstrated that feedback was beneficial only in the complex tasks (block turn, clothespin and cups relocation), and that the training had an important, task-dependent impact. In the clothespin relocation and block turn tasks, training allowed the subjects to establish successful feedforward control, and therefore, the feedback became redundant. In the cups relocation task, however, the subjects needed some training to learn how to properly exploit the feedback. The subjective evaluation of the feedback was consistently positive, regardless of the objective benefits. These results underline the multifaceted nature of closed-loop prosthesis control as, depending on the context, the same feedback interface can have different impact on performance. Finally, even if the closed-loop control does not improve the performance, it could be beneficial as it seems to improve the subjective experience. Therefore, in this study we demonstrate, for the first time, the relevance of an advanced, multi-variable feedback interface for dexterous, multi-functional prosthesis control in a clinically relevant setting.

Users of withdrawal method in the Islamic Republic of Iran: are they intending to use oral contraceptives? Applying the theory of planned behaviour.

PubMed

Rahnama, P; Hidarnia, A; Shokravi, F A; Kazemnejad, A; Montazeri, A; Najorkolaei, F R; Saburi, A

2013-09-01

Many couples in the Islamic Republic of Iran rely on coital withdrawal for contraception. The purpose of this cross-sectional study was to use the theory of planned behaviour to explore factors that influence withdrawal users' intent to switch to oral contraception (OC). Participants were 336 sexually active, married women, who were current users of withdrawal and were recruited from 5 public family planning clinics in Tehran. A questionnair included measures of the theory of planned behaviour: attitude (behavioural beliefs, outcome evaluations), subjective norms (normative beliefs, motivation to comply), perceived behaviour control, past behaviour and behavioural intention. Linear regression analyses showed that past behaviour, perceived behaviour control, attitude and subjective norms accounted for the highest percentage of total variance observed for intention to use OC (36%). Beliefs-based family planning education and counsellingshould to be designed for users of the withdrawal method.

Joystick-controlled video console game practice for developing power wheelchairs users' indoor driving skills.

PubMed

Huang, Wei Pin; Wang, Chia Cheng; Hung, Jo Hua; Chien, Kai Chun; Liu, Wen-Yu; Cheng, Chih-Hsiu; Ng, How-Hing; Lin, Yang-Hua

2015-02-01

[Purpose] This study aimed to determine the effectiveness of joystick-controlled video console games in enhancing subjects' ability to control power wheelchairs. [Subjects and Methods] Twenty healthy young adults without prior experience of driving power wheelchairs were recruited. Four commercially available video games were used as training programs to practice joystick control in catching falling objects, crossing a river, tracing the route while floating on a river, and navigating through a garden maze. An indoor power wheelchair driving test, including straight lines, and right and left turns, was completed before and after the video game practice, during which electromyographic signals of the upper limbs were recorded. The paired t-test was used to compare the differences in driving performance and muscle activities before and after the intervention. [Results] Following the video game intervention, participants took significantly less time to complete the course, with less lateral deviation when turning the indoor power wheelchair. However, muscle activation in the upper limbs was not significantly affected. [Conclusion] This study demonstrates the feasibility of using joystick-controlled commercial video games to train individuals in the control of indoor power wheelchairs.

Optimizing height presentation for aircraft cockpit displays

NASA Astrophysics Data System (ADS)

Jordan, Chris S.; Croft, D.; Selcon, Stephen J.; Markin, H.; Jackson, M.

1997-02-01

This paper describes an experiment conducted to investigate the type of display symbology that most effectively conveys height information to users of head-down plan-view radar displays. The experiment also investigated the use of multiple information sources (redundancy) in the design of such displays. Subjects were presented with eight different height display formats. These formats were constructed from a control, and/or one, two, or three sources of redundant information. The three formats were letter coding, analogue scaling, and toggling (spatially switching the position of the height information from above to below the aircraft symbol). Subjects were required to indicate altitude awareness via a four-key, forced-choice keyboard response. Error scores and response times were taken as performance measures. There were three main findings. First, there was a significant performance advantage when the altitude information was presented above and below the symbol to aid the representation of height information. Second, the analogue scale, a line whose length indicated altitude, proved significantly detrimental to performance. Finally, no relationship was found between the number of redundant information sources employed and performance. The implications for future aircraft and displays are discussed in relation to current aircraft tactical displays and in the context of perceptual psychological theory.

Cerebral metabolic dysfunction and impaired vigilance in recently abstinent methamphetamine abusers.

PubMed

London, Edythe D; Berman, Steven M; Voytek, Bradley; Simon, Sara L; Mandelkern, Mark A; Monterosso, John; Thompson, Paul M; Brody, Arthur L; Geaga, Jennifer A; Hong, Michael S; Hayashi, Kiralee M; Rawson, Richard A; Ling, Walter

2005-11-15

Methamphetamine (MA) abusers have cognitive deficits, abnormal metabolic activity and structural deficits in limbic and paralimbic cortices, and reduced hippocampal volume. The links between cognitive impairment and these cerebral abnormalities are not established. We assessed cerebral glucose metabolism with [F-18]fluorodeoxyglucose positron emission tomography in 17 abstinent (4 to 7 days) methamphetamine users and 16 control subjects performing an auditory vigilance task and obtained structural magnetic resonance brain scans. Regional brain radioactivity served as a marker for relative glucose metabolism. Error rates on the task were related to regional radioactivity and hippocampal morphology. Methamphetamine users had higher error rates than control subjects on the vigilance task. The groups showed different relationships between error rates and relative activity in the anterior and middle cingulate gyrus and the insula. Whereas the MA user group showed negative correlations involving these regions, the control group showed positive correlations involving the cingulate cortex. Across groups, hippocampal metabolic and structural measures were negatively correlated with error rates. Dysfunction in the cingulate and insular cortices of recently abstinent MA abusers contribute to impaired vigilance and other cognitive functions requiring sustained attention. Hippocampal integrity predicts task performance in methamphetamine users as well as control subjects.

Mapping Phonetic Features for Voice-Driven Sound Synthesis

NASA Astrophysics Data System (ADS)

Janer, Jordi; Maestre, Esteban

In applications where the human voice controls the synthesis of musical instruments sounds, phonetics convey musical information that might be related to the sound of the imitated musical instrument. Our initial hypothesis is that phonetics are user- and instrument-dependent, but they remain constant for a single subject and instrument. We propose a user-adapted system, where mappings from voice features to synthesis parameters depend on how subjects sing musical articulations, i.e. note to note transitions. The system consists of two components. First, a voice signal segmentation module that automatically determines note-to-note transitions. Second, a classifier that determines the type of musical articulation for each transition based on a set of phonetic features. For validating our hypothesis, we run an experiment where subjects imitated real instrument recordings with their voice. Performance recordings consisted of short phrases of saxophone and violin performed in three grades of musical articulation labeled as: staccato, normal, legato. The results of a supervised training classifier (user-dependent) are compared to a classifier based on heuristic rules (user-independent). Finally, from the previous results we show how to control the articulation in a sample-concatenation synthesizer by selecting the most appropriate samples.

Bias Correction of Satellite Precipitation Products (SPPs) using a User-friendly Tool: A Step in Enhancing Technical Capacity

NASA Astrophysics Data System (ADS)

Rushi, B. R.; Ellenburg, W. L.; Adams, E. C.; Flores, A.; Limaye, A. S.; Valdés-Pineda, R.; Roy, T.; Valdés, J. B.; Mithieu, F.; Omondi, S.

2017-12-01

SERVIR, a joint NASA-USAID initiative, works to build capacity in Earth observation technologies in developing countries for improved environmental decision making in the arena of: weather and climate, water and disasters, food security and land use/land cover. SERVIR partners with leading regional organizations in Eastern and Southern Africa, Hindu Kush-Himalaya, Mekong region, and West Africa to achieve its objectives. SERVIR develops hydrological applications to address specific needs articulated by key stakeholders and daily rainfall estimates are a vital input for these applications. Satellite-derived rainfall is subjected to systemic biases which need to be corrected before it can be used for any hydrologic application such as real-time or seasonal forecasting. SERVIR and the SWAAT team at the University of Arizona, have co-developed an open-source and user friendly tool of rainfall bias correction approaches for SPPs. Bias correction tools were developed based on Linear Scaling and Quantile Mapping techniques. A set of SPPs, such as PERSIANN-CCS, TMPA-RT, and CMORPH, are bias corrected using Climate Hazards Group InfraRed Precipitation with Station (CHIRPS) data which incorporates ground based precipitation observations. This bias correction tools also contains a component, which is included to improve monthly mean of CHIRPS using precipitation products of the Global Surface Summary of the Day (GSOD) database developed by the National Climatic Data Center (NCDC). This tool takes input from command-line which makes it user-friendly and applicable in any operating platform without prior programming skills. This presentation will focus on this bias-correction tool for SPPs, including application scenarios.

A Stereo Music Preprocessing Scheme for Cochlear Implant Users.

PubMed

Buyens, Wim; van Dijk, Bas; Wouters, Jan; Moonen, Marc

2015-10-01

Listening to music is still one of the more challenging aspects of using a cochlear implant (CI) for most users. Simple musical structures, a clear rhythm/beat, and lyrics that are easy to follow are among the top factors contributing to music appreciation for CI users. Modifying the audio mix of complex music potentially improves music enjoyment in CI users. A stereo music preprocessing scheme is described in which vocals, drums, and bass are emphasized based on the representation of the harmonic and the percussive components in the input spectrogram, combined with the spatial allocation of instruments in typical stereo recordings. The scheme is assessed with postlingually deafened CI subjects (N = 7) using pop/rock music excerpts with different complexity levels. The scheme is capable of modifying relative instrument level settings, with the aim of improving music appreciation in CI users, and allows individual preference adjustments. The assessment with CI subjects confirms the preference for more emphasis on vocals, drums, and bass as offered by the preprocessing scheme, especially for songs with higher complexity. The stereo music preprocessing scheme has the potential to improve music enjoyment in CI users by modifying the audio mix in widespread (stereo) music recordings. Since music enjoyment in CI users is generally poor, this scheme can assist the music listening experience of CI users as a training or rehabilitation tool.

Categorization of compensatory motions in transradial myoelectric prosthesis users.

PubMed

Hussaini, Ali; Zinck, Arthur; Kyberd, Peter

2017-06-01

Prosthesis users perform various compensatory motions to accommodate for the loss of the hand and wrist as well as the reduced functionality of a prosthetic hand. Investigate different compensation strategies that are performed by prosthesis users. Comparative analysis. A total of 20 able-bodied subjects and 4 prosthesis users performed a set of bimanual activities. Movements of the trunk and head were recorded using a motion capture system and a digital video recorder. Clinical motion angles were calculated to assess the compensatory motions made by the prosthesis users. The video recording also assisted in visually identifying the compensations. Compensatory motions by the prosthesis users were evident in the tasks performed (slicing and stirring activities) as compared to the benchmark of able-bodied subjects. Compensations took the form of a measured increase in range of motion, an observed adoption of a new posture during task execution, and prepositioning of items in the workspace prior to initiating a given task. Compensatory motions were performed by prosthesis users during the selected tasks. These can be categorized into three different types of compensations. Clinical relevance Proper identification and classification of compensatory motions performed by prosthesis users into three distinct forms allows clinicians and researchers to accurately identify and quantify movement. It will assist in evaluating new prosthetic interventions by providing distinct terminology that is easily understood and can be shared between research institutions.

Implicit Associations and Explicit Expectancies toward Cannabis in Heavy Cannabis Users and Controls

PubMed Central

Beraha, Esther M.; Cousijn, Janna; Hermanides, Elisa; Goudriaan, Anna E.; Wiers, Reinout W.

2013-01-01

Cognitive biases, including implicit memory associations are thought to play an important role in the development of addictive behaviors. The aim of the present study was to investigate implicit affective memory associations in heavy cannabis users. Implicit positive-arousal, sedation, and negative associations toward cannabis were measured with three Single Category Implicit Association Tests (SC-IAT’s) and compared between 59 heavy cannabis users and 89 controls. Moreover, we investigated the relationship between these implicit affective associations and explicit expectancies, subjective craving, cannabis use, and cannabis related problems. Results show that heavy cannabis users had stronger implicit positive-arousal associations but weaker implicit negative associations toward cannabis compared to controls. Moreover, heavy cannabis users had stronger sedation but weaker negative explicit expectancies toward cannabis compared to controls. Within heavy cannabis users, more cannabis use was associated with stronger implicit negative associations whereas more cannabis use related problems was associated with stronger explicit negative expectancies, decreasing the overall difference on negative associations between cannabis users and controls. No other associations were observed between implicit associations, explicit expectancies, measures of cannabis use, cannabis use related problems, or subjective craving. These findings indicate that, in contrast to other substances of abuse like alcohol and tobacco, the relationship between implicit associations and cannabis use appears to be weak in heavy cannabis users. PMID:23801968

Telomere length in non-neoplastic gastric mucosa and its relationship to H. pylori infection, degree of gastritis, and NSAID use.

PubMed

Tahara, Tomomitsu; Shibata, Tomoyuki; Kawamura, Tomohiko; Ishizuka, Takamitsu; Okubo, Masaaki; Nagasaka, Mitsuo; Nakagawa, Yoshihito; Arisawa, Tomiyasu; Ohmiya, Naoki; Hirata, Ichiro

2016-02-01

Telomere shortening occurs with human aging in many organs and tissues and is accelerated by rapid cell turnover and oxidative injury. We measured average telomere length using quantitative real-time PCR in non-neoplastic gastric mucosa and assessed its relationship to H. pylori-related gastritis, DNA methylation, ulcer disease, and nonsteroidal anti-inflammatory drug (NSAID) usage. Gastric biopsies were obtained from 151 cancer-free subjects including 49 chronic NSAID users and 102 nonusers. Relative telomere length in genomic DNA was measured by real-time PCR. H. pylori infection status, histological severity of gastritis, and serum pepsinogens (PGs) were also investigated. E-cadherin (CDH1) methylation status was determined by methylation-specific PCR (MSP). Average relative telomere length of H. pylori-infected subjects was significantly shortened when compared to H. pylori-negative subjects (p = 0.002) and was closely associated with all histological parameter of gastritis (all p values <0.01) and CDH1 methylation (p = 0.0002). In H. pylori-negative subjects, NSAID users presented significantly shorter telomere length than nonusers (p = 0.028). Shorter telomere length was observed in duodenal and gastric ulcer patients compared with non-ulcer subjects among NSAID users. Telomere shortening is closely associated with severity of H. pylori-induced gastritis and CDH1 methylation status. Also, telomere shortening is accelerated by NSAID usage especially in H. pylori-negative subjects.

The Facebook paths to happiness: effects of the number of Facebook friends and self-presentation on subjective well-being.

PubMed

Kim, Junghyun; Lee, Jong-Eun Roselyn

2011-06-01

The current study investigates whether and how Facebook increases college-age users' subjective well-being by focusing on the number of Facebook friends and self-presentation strategies (positive vs. honest). A structural equation modeling analysis of cross-sectional survey data of college student Facebook users (N=391) revealed that the number of Facebook friends had a positive association with subjective well-being, but this association was not mediated by perceived social support. Additionally, we found that there was a negative curvilinear (inverted U-shape curve) relationship between Facebook friends and perceived social support. As for self-presentation strategies, whereas positive self-presentation had a direct effect on subjective well-being, honest self-presentation had a significant indirect effect on subjective well-being through perceived social support. Our study suggests that the number of Facebook friends and positive self-presentation may enhance users' subjective well-being, but this portion of happiness may not be grounded in perceived social support. On the other hand, honest self-presentation may enhance happiness rooted in social support provided by Facebook friends. Implications of our findings are discussed in light of affirmation of self-worth, time and effort required for building and maintaining friendships, and the important role played by self-disclosure in signaling one's need for social support.

Effects of acute buspirone administration on inhibitory control and sexual discounting in cocaine users.

PubMed

Strickland, Justin C; Bolin, B Levi; Romanelli, Michael R; Rush, Craig R; Stoops, William W

2017-01-01

Cocaine users display deficits in inhibitory control and make impulsive choices that may increase risky behavior. Buspirone is an anxiolytic that activates dopaminergic and serotonergic systems and improves impulsive choice (i.e., reduces sexual risk-taking intent) in cocaine users when administered chronically. We evaluated the effects of acutely administered buspirone on inhibitory control and impulsive choice. Eleven subjects with a recent history of cocaine use completed this within-subject, placebo-controlled study. Subjects performed two cued go/no-go and a sexual risk delay-discounting task following oral administration of buspirone (10 and 30 mg), triazolam (0.375 mg; positive control), and placebo (negative control). Physiological and psychomotor performance and subject-rated data were also collected. Buspirone failed to change inhibitory control or impulsive choice; however, slower reaction times were observed at the highest dose tested. Buspirone did not produce subject-rated drug effects but dose-dependently decreased diastolic blood pressure. Triazolam impaired psychomotor performance and increased ratings of positive subject-rated effects (e.g., Like Drug). These findings indicate that acutely administered buspirone has little impact on behavioral measures of inhibitory control and impulsive sexual decision-making. Considering previous findings with chronic dosing, these findings highlight that the behavioral effects of buspirone differ as a function of dosing conditions. Copyright © 2017 John Wiley & Sons, Ltd.

Comparing Text-based and Graphic User Interfaces for Novice and Expert Users

PubMed Central

Chen, Jung-Wei; Zhang, Jiajie

2007-01-01

Graphic User Interface (GUI) is commonly considered to be superior to Text-based User Interface (TUI). This study compares GUI and TUI in an electronic dental record system. Several usability analysis techniques compared the relative effectiveness of a GUI and a TUI. Expert users and novice users were evaluated in time required and steps needed to complete the task. A within-subject design was used to evaluate if the experience with either interface will affect task performance. The results show that the GUI interface was not better than the TUI for expert users. GUI interface was better for novice users. For novice users there was a learning transfer effect from TUI to GUI. This means a user interface is user-friendly or not depending on the mapping between the user interface and tasks. GUI by itself may or may not be better than TUI. PMID:18693811

Comparing Text-based and Graphic User Interfaces for novice and expert users.

PubMed

Chen, Jung-Wei; Zhang, Jiajie

2007-10-11

Graphic User Interface (GUI) is commonly considered to be superior to Text-based User Interface (TUI). This study compares GUI and TUI in an electronic dental record system. Several usability analysis techniques compared the relative effectiveness of a GUI and a TUI. Expert users and novice users were evaluated in time required and steps needed to complete the task. A within-subject design was used to evaluate if the experience with either interface will affect task performance. The results show that the GUI interface was not better than the TUI for expert users. GUI interface was better for novice users. For novice users there was a learning transfer effect from TUI to GUI. This means a user interface is user-friendly or not depending on the mapping between the user interface and tasks. GUI by itself may or may not be better than TUI.

Lip line preference for variant face types.

PubMed

Anwar, Nabila; Fida, Mubassar

2012-06-01

To determine the effect of altered lip line on attractiveness and to find preferred lip line for vertical face types in both genders. Cross-sectional analytical study. The Aga Khan University Hospital, Karachi, from May to July 2009. Photographs of two selected subjects were altered to produce three face types for the same individual with the aim of keeping the frame of the smile constant. Lip line was then altered for both the subjects as: both dentitions visible, upper incisors visible, upper incisors and 2 mm gum and 4 mm gum visible. The pictures were rated by different professionals for attractiveness. Descriptive statistics for the raters and multiple factor ANOVA was used to find the most attractive lip line. The total number of raters was 100 with the mean age of 30.3 ± 8 years. The alterations in the smile parameters produced statistically significant difference in the attractiveness of faces, whereas the perception difference was found to be insignificant amongst raters of different professions. Preferred lip line was the one showing only the upper incisors in dolico and mesofacial male and female genders whereas 2 mm gum show was preferred in brachyfacial subjects. The variability in lip line showed significant difference in the perceived attractiveness. Preferred lip lines as the one showing only the upper incisors in dolico and mesofacial male and female genders whereas 2 mm gum show was preferred in brachyfacial subjects.

PASSIM--an open source software system for managing information in biomedical studies.

PubMed

Viksna, Juris; Celms, Edgars; Opmanis, Martins; Podnieks, Karlis; Rucevskis, Peteris; Zarins, Andris; Barrett, Amy; Neogi, Sudeshna Guha; Krestyaninova, Maria; McCarthy, Mark I; Brazma, Alvis; Sarkans, Ugis

2007-02-09

One of the crucial aspects of day-to-day laboratory information management is collection, storage and retrieval of information about research subjects and biomedical samples. An efficient link between sample data and experiment results is absolutely imperative for a successful outcome of a biomedical study. Currently available software solutions are largely limited to large-scale, expensive commercial Laboratory Information Management Systems (LIMS). Acquiring such LIMS indeed can bring laboratory information management to a higher level, but often implies sufficient investment of time, effort and funds, which are not always available. There is a clear need for lightweight open source systems for patient and sample information management. We present a web-based tool for submission, management and retrieval of sample and research subject data. The system secures confidentiality by separating anonymized sample information from individuals' records. It is simple and generic, and can be customised for various biomedical studies. Information can be both entered and accessed using the same web interface. User groups and their privileges can be defined. The system is open-source and is supplied with an on-line tutorial and necessary documentation. It has proven to be successful in a large international collaborative project. The presented system closes the gap between the need and the availability of lightweight software solutions for managing information in biomedical studies involving human research subjects.

Learning to walk with an adaptive gain proportional myoelectric controller for a robotic ankle exoskeleton.

PubMed

Koller, Jeffrey R; Jacobs, Daniel A; Ferris, Daniel P; Remy, C David

2015-11-04

Robotic ankle exoskeletons can provide assistance to users and reduce metabolic power during walking. Our research group has investigated the use of proportional myoelectric control for controlling robotic ankle exoskeletons. Previously, these controllers have relied on a constant gain to map user's muscle activity to actuation control signals. A constant gain may act as a constraint on the user, so we designed a controller that dynamically adapts the gain to the user's myoelectric amplitude. We hypothesized that an adaptive gain proportional myoelectric controller would reduce metabolic energy expenditure compared to walking with the ankle exoskeleton unpowered because users could choose their preferred control gain. We tested eight healthy subjects walking with the adaptive gain proportional myoelectric controller with bilateral ankle exoskeletons. The adaptive gain was updated each stride such that on average the user's peak muscle activity was mapped to maximal power output of the exoskeleton. All subjects participated in three identical training sessions where they walked on a treadmill for 50 minutes (30 minutes of which the exoskeleton was powered) at 1.2 ms(-1). We calculated and analyzed metabolic energy consumption, muscle recruitment, inverse kinematics, inverse dynamics, and exoskeleton mechanics. Using our controller, subjects achieved a metabolic reduction similar to that seen in previous work in about a third of the training time. The resulting controller gain was lower than that seen in previous work (β=1.50±0.14 versus a constant β=2). The adapted gain allowed users more total ankle joint power than that of unassisted walking, increasing ankle power in exchange for a decrease in hip power. Our findings indicate that humans prefer to walk with greater ankle mechanical power output than their unassisted gait when provided with an ankle exoskeleton using an adaptive controller. This suggests that robotic assistance from an exoskeleton can allow humans to adopt gait patterns different from their normal choices for locomotion. In our specific experiment, subjects increased ankle power and decreased hip power to walk with a reduction in metabolic cost. Future exoskeleton devices that rely on proportional myolectric control are likely to demonstrate improved performance by including an adaptive gain.

Patron Survey of User Satisfaction with Library Services: Relationship between Librarian Behaviors during the Reference Interview and User Satisfaction.

ERIC Educational Resources Information Center

Nichols, Mary Ellen

This study examined whether user satisfaction with library services is affected by certain objective and subjective librarian behaviors exhibited during the reference interview. A patron survey was conducted during July 1993 in three branches of Cuyahoga County Public Library, located in northeastern Ohio. The sample was determined by the patrons…

The Drug User's Identity and How It Relates to Being Hepatitis C Antibody Positive: A Qualitative Study

ERIC Educational Resources Information Center

Copeland, Lorraine

2004-01-01

The increasing health problem of hepatitis C virus infection has only recently attracted the attention of psychosocial research, especially among subjects at higher risk (e.g. injecting drug users). There is a lack of information about the knowledge, perceptions and feelings that injecting drug users hold about their hepatitis C antibody positive…

Linux VPN Set Up | High-Performance Computing | NREL

Science.gov Websites

methods to connect to NREL's HPC systems via the HPC VPN: one using a simple command line, and a second UserID in place of the one in the example image. Connection name: hpcvpn Gateway: hpcvpn.nrel.gov User hpcvpn option as seen in the following screen shot. Screenshot image NetworkManager will present you with

47 CFR 63.17 - Special provisions for U.S. international common carriers.

Code of Federal Regulations, 2014 CFR

2014-10-01

... carrier, may interconnect its authorized private lines to the public switched network on behalf of an end user customer for the end user customer's own use. (b) Except as provided in paragraph (b)(4) of this... World Wide Web site at http://www.fcc.gov/ib. (3) Authorized carriers filing tariffs pursuant to §§ 61...

47 CFR 63.17 - Special provisions for U.S. international common carriers.

Code of Federal Regulations, 2013 CFR

2013-10-01

... carrier, may interconnect its authorized private lines to the public switched network on behalf of an end user customer for the end user customer's own use. (b) Except as provided in paragraph (b)(4) of this... World Wide Web site at http://www.fcc.gov/ib. (3) Authorized carriers filing tariffs pursuant to §§ 61...

From to : Nicknames, Play and Identity on Internet Relay Chat.

ERIC Educational Resources Information Center

Bechar-Israeli, Haya

1995-01-01

Examines nicknames of Internet Relay Chat (IRC) users, whose identities are condensed into a single line which states their nicknames, the electronic address, and a slogan or the users' real names. Demonstrates that although people play games with their nicknames, the nicknames they choose are an inherent part of their Net identity and their…

Words That Fascinate the Listener: Predicting Affective Ratings of On-Line Lectures

ERIC Educational Resources Information Center

Weninger, Felix; Staudt, Pascal; Schuller, Björn

2013-01-01

In a large scale study on 843 transcripts of Technology, Entertainment and Design (TED) talks, the authors address the relation between word usage and categorical affective ratings of lectures by a large group of internet users. Users rated the lectures by assigning one or more predefined tags which relate to the affective state evoked in the…

EnviroNET: An on-line environment data base for LDEF data

NASA Technical Reports Server (NTRS)

Lauriente, Michael

1992-01-01

EnviroNET is an on-line, free form data base intended to provide a centralized depository for a wide range of technical information on environmentally induced interactions of use to Space Shuttle customers and spacecraft designers. It provides a user friendly, menu driven format on networks that are connected globally and is available twenty-four hours a day, every day. The information updated regularly, includes expository text, tabular numerical data, charts and graphs, and models. The system pools space data collected over the years by NASA, USAF, other government facilities, industry, universities, and ESA. The models accept parameter input from the user and calculate and display the derived values corresponding to that input. In addition to the archive, interactive graphics programs are also available on space debris, the neutral atmosphere, radiation, magnetic field, and ionosphere. A user friendly informative interface is standard for all the models with a pop-up window, help window with information on inputs, outputs, and caveats. The system will eventually simplify mission analysis with analytical tools and deliver solution for computational intense graphical applications to do 'What if' scenarios. A proposed plan for developing a repository of LDEF information for a user group concludes the presentation.

From fragments to the whole: a comparison between cochlear implant users and normal-hearing listeners in music perception and enjoyment.

PubMed

Alexander, Ashlin J; Bartel, Lee; Friesen, Lendra; Shipp, David; Chen, Joseph

2011-02-01

Cochlear implants (CIs) allow many profoundly deaf individuals to regain speech understanding. However, the ability to understand speech does not necessarily guarantee music enjoyment. Enabling a CI user to recover the ability to perceive and enjoy the complexity of music remains a challenge determined by many factors. (1) To construct a novel, attention-based, diagnostic software tool (Music EAR) for the assessment of music enjoyment and perception and (2) to compare the results among three listener groups. Thirty-six subjects completed the Music EAR assessment tool: 12 normal-hearing musicians (NHMs), 12 normal-hearing nonmusicians (NHnMs), and 12 CI listeners. Subjects were required to (1) rate enjoyment of musical excerpts at three complexity levels; (2) differentiate five instrumental timbres; (3) recognize pitch pattern variation; and (4) identify target musical patterns embedded holistically in a melody. Enjoyment scores for CI users were comparable to those for NHMs and superior to those for NHnMs and revealed that implantees enjoyed classical music most. CI users performed significantly poorer in all categories of music perception compared to normal-hearing listeners. Overall CI user scores were lowest in those tasks requiring increased attention. Two high-performing subjects matched or outperformed NHnMs in pitch and timbre perception tasks. The Music EAR assessment tool provides a unique approach to the measurement of music perception and enjoyment in CI users. Together with auditory training evidence, the results provide considerable hope for further recovery of music appreciation through methodical rehabilitation.

Assessing the effects of non-steroidal anti-inflammatory drugs on antihypertensive drug therapy using post-marketing surveillance database.

PubMed

Ishiguro, Chieko; Fujita, Toshiharu; Omori, Takashi; Fujii, Yosuke; Mayama, Takeshi; Sato, Tosiya

2008-01-01

Antihypertensive and non-steroidal anti-inflammatory drugs (NSAIDs) are used to treat many common diseases. However, it has been suspected that interactions between these drugs exist. Here, we assessed the interactions between non-selective NSAIDs and several classes of antihypertensive drugs. The study design was a cohort study using "The Antihypertensive Drug Database," which is a collection of data accumulated from Drug Use Investigations. Subjects newly starting antihypertensive drug therapy were identified in the database. We compared the "User" group, who were co-administered NSAIDs, with the "Non-user" group, who were not. The outcome measure was the change in systolic blood pressure from the baseline after 2 months of treatment. We estimated the non-adjusted and adjusted differences in the change in systolic blood pressure between the "User" and "Non-user" groups. Data were collected for a total of 1,204 subjects, of whom 364 were prescribed beta blockers, 60 were prescribed diuretics, 628 were prescribed angiotensin-converting enzyme inhibitors, and 152 were prescribed calcium channel blockers. The adjusted difference in the change in systolic blood pressure between the User (n = 301) and Non-user (n = 903) groups was 2.88 mmHg (95% confidence interval: 0.89, 4.87); thus, systolic blood pressure in the Non-User group decreased further from the baseline than that in the User group. In subjects administered beta blockers, diuretics, angiotensin-converting enzyme inhibitors, and calcium channel blockers, the corresponding differences were 0.37 mmHg (-3.24, 3.98), 6.11 mmHg (-3.16, 15.37), 3.85 mmHg (1.16, 6.66), and 3.50 mmHg (-2.03, 9.02). The effectiveness of antihypertensive drugs was attenuated by the co-administration of NSAIDs. The differences in the effects of NSAIDs varied with different classes of antihypertensive drugs.

Effects of congruent and incongruent visual cues on speech perception and brain activity in cochlear implant users.

PubMed

Song, Jae-Jin; Lee, Hyo-Jeong; Kang, Hyejin; Lee, Dong Soo; Chang, Sun O; Oh, Seung Ha

2015-03-01

While deafness-induced plasticity has been investigated in the visual and auditory domains, not much is known about language processing in audiovisual multimodal environments for patients with restored hearing via cochlear implant (CI) devices. Here, we examined the effect of agreeing or conflicting visual inputs on auditory processing in deaf patients equipped with degraded artificial hearing. Ten post-lingually deafened CI users with good performance, along with matched control subjects, underwent H 2 (15) O-positron emission tomography scans while carrying out a behavioral task requiring the extraction of speech information from unimodal auditory stimuli, bimodal audiovisual congruent stimuli, and incongruent stimuli. Regardless of congruency, the control subjects demonstrated activation of the auditory and visual sensory cortices, as well as the superior temporal sulcus, the classical multisensory integration area, indicating a bottom-up multisensory processing strategy. Compared to CI users, the control subjects exhibited activation of the right ventral premotor-supramarginal pathway. In contrast, CI users activated primarily the visual cortices more in the congruent audiovisual condition than in the null condition. In addition, compared to controls, CI users displayed an activation focus in the right amygdala for congruent audiovisual stimuli. The most notable difference between the two groups was an activation focus in the left inferior frontal gyrus in CI users confronted with incongruent audiovisual stimuli, suggesting top-down cognitive modulation for audiovisual conflict. Correlation analysis revealed that good speech performance was positively correlated with right amygdala activity for the congruent condition, but negatively correlated with bilateral visual cortices regardless of congruency. Taken together these results suggest that for multimodal inputs, cochlear implant users are more vision-reliant when processing congruent stimuli and are disturbed more by visual distractors when confronted with incongruent audiovisual stimuli. To cope with this multimodal conflict, CI users activate the left inferior frontal gyrus to adopt a top-down cognitive modulation pathway, whereas normal hearing individuals primarily adopt a bottom-up strategy.

Speech intelligibility and subjective benefit in single-sided deaf adults after cochlear implantation.

PubMed

Finke, Mareike; Strauß-Schier, Angelika; Kludt, Eugen; Büchner, Andreas; Illg, Angelika

2017-05-01

Treatment with cochlear implants (CIs) in single-sided deaf individuals started less than a decade ago. CIs can successfully reduce incapacitating tinnitus on the deaf ear and allow, so some extent, the restoration of binaural hearing. Until now, systematic evaluations of subjective CI benefit in post-lingually single-sided deaf individuals and analyses of speech intelligibility outcome for the CI in isolation have been lacking. For the prospective part of this study, the Bern Benefit in Single-Sided Deafness Questionnaire (BBSS) was administered to 48 single-sided deaf CI users to evaluate the subjectively perceived CI benefit across different listening situations. In the retrospective part, speech intelligibility outcome with the CI up to 12 month post-activation was compared between 100 single-sided deaf CI users and 125 bilaterally implanted CI users (2nd implant). The positive median ratings in the BBSS differed significantly from zero for all items suggesting that most individuals with single-sided deafness rate their CI as beneficial across listening situations. The speech perception scores in quiet and noise improved significantly over time in both groups of CI users. Speech intelligibility with the CI in isolation was significantly better in bilaterally implanted CI users (2nd implant) compared to the scores obtained from single-sided deaf CI users. Our results indicate that CI users with single-sided deafness can reach open set speech understanding with their CI in isolation, encouraging the extension of the CI indication to individuals with normal hearing on the contralateral ear. Compared to the performance reached with bilateral CI users' second implant, speech reception threshold are lower, indicating an aural preference and dominance of the normal hearing ear. The results from the BBSS propose good satisfaction with the CI across several listening situations. Copyright © 2017 Elsevier B.V. All rights reserved.

Adapting human-machine interfaces to user performance.

PubMed

Danziger, Zachary; Fishbach, Alon; Mussa-Ivaldi, Ferdinando A

2008-01-01

The goal of this study was to create and examine machine learning algorithms that adapt in a controlled and cadenced way to foster a harmonious learning environment between the user of a human-machine interface and the controlled device. In this experiment, subjects' high-dimensional finger motions remotely controlled the joint angles of a simulated planar 2-link arm, which was used to hit targets on a computer screen. Subjects were required to move the cursor at the endpoint of the simulated arm.

Effect of Atropine and 2-PAM Chloride on Vision and Performance.

DTIC Science & Technology

1986-05-31

occasional users of alcohol and marijuana ; one subject was a frequent user of marijuana . Our subjects were asked to refrain from all other drugs...during the experiment (including alcohol and coffee). In addition, they did not smoke any marijuana for at least 2 weeks prior to the start of the...emitting diode ( LED ) mounted on the side, moves in a fixed arc at a simulated distance of I km and a constant angular velocity of 5 mrad/sec. The

Clinical use of proton-pump inhibitors but not H2-blockers or antacid/alginates raises the serum levels of amidated gastrin-17, pepsinogen I and pepsinogen II in a random adult population.

PubMed

Agréus, Lars; Storskrubb, Tom; Aro, Pertti; Ronkainen, Jukka; Talley, Nicholas J; Sipponen, Pentti

2009-01-01

Proton-pump inhibitors (PPIs), H(2) receptor antagonists (H(2)RAs) and antacids/alginates reduce intragastric acidity and may thus influence normal gastric physiology. The purpose of this study was to examine the effect of these compounds on serum levels of amidated gastrin-17 (G-17) and pepsinogens (PGI & PGII) in a large, random, adult Swedish population sample with uninfected stomach mucosa. The initial sample subjects (n=1000, mean age 50 years, range 20-80 years) completed a questionnaire on the use of acid inhibitory drugs 1 week and/or 3 months before study entry. All subjects (n=590) with normal gastric mucosa as delineated by serum biomarkers were included. Among them, serum levels of PGI, PGII and G-17 were compared between those who used acid inhibitory drugs and those who did not. The serum levels of G-17 or pepsinogens in the subjects who reported use of H(2)RAs (n=18) or antacid/alginates (n=66) during the previous 3 months did not differ from those in non-users (n=471). However, the median levels of G-17 and pepsinogens were significantly (p<0.001) higher among the PPI users (n=35) than among non-users: the levels were approximately doubled. The ratio of PGI/PGII was, however, similar between PPI users and non-users, or those using antacids/alginates or H(2)RAs. Among subjects using PPIs, the serum levels of pepsinogens correlated positively (p<0.01) with the serum levels of G-17. PPIs but not antacids/alginates or H(2)RAs markedly increase the fasting levels of serum amidated G-17 and pepsinogens among ordinary patients in everyday clinical practice.

Collaborative filtering for brain-computer interaction using transfer learning and active class selection.

PubMed

Wu, Dongrui; Lance, Brent J; Parsons, Thomas D

2013-01-01

Brain-computer interaction (BCI) and physiological computing are terms that refer to using processed neural or physiological signals to influence human interaction with computers, environment, and each other. A major challenge in developing these systems arises from the large individual differences typically seen in the neural/physiological responses. As a result, many researchers use individually-trained recognition algorithms to process this data. In order to minimize time, cost, and barriers to use, there is a need to minimize the amount of individual training data required, or equivalently, to increase the recognition accuracy without increasing the number of user-specific training samples. One promising method for achieving this is collaborative filtering, which combines training data from the individual subject with additional training data from other, similar subjects. This paper describes a successful application of a collaborative filtering approach intended for a BCI system. This approach is based on transfer learning (TL), active class selection (ACS), and a mean squared difference user-similarity heuristic. The resulting BCI system uses neural and physiological signals for automatic task difficulty recognition. TL improves the learning performance by combining a small number of user-specific training samples with a large number of auxiliary training samples from other similar subjects. ACS optimally selects the classes to generate user-specific training samples. Experimental results on 18 subjects, using both k nearest neighbors and support vector machine classifiers, demonstrate that the proposed approach can significantly reduce the number of user-specific training data samples. This collaborative filtering approach will also be generalizable to handling individual differences in many other applications that involve human neural or physiological data, such as affective computing.

Spectrotemporal Modulation Detection and Speech Perception by Cochlear Implant Users

PubMed Central

Won, Jong Ho; Moon, Il Joon; Jin, Sunhwa; Park, Heesung; Woo, Jihwan; Cho, Yang-Sun; Chung, Won-Ho; Hong, Sung Hwa

2015-01-01

Spectrotemporal modulation (STM) detection performance was examined for cochlear implant (CI) users. The test involved discriminating between an unmodulated steady noise and a modulated stimulus. The modulated stimulus presents frequency modulation patterns that change in frequency over time. In order to examine STM detection performance for different modulation conditions, two different temporal modulation rates (5 and 10 Hz) and three different spectral modulation densities (0.5, 1.0, and 2.0 cycles/octave) were employed, producing a total 6 different STM stimulus conditions. In order to explore how electric hearing constrains STM sensitivity for CI users differently from acoustic hearing, normal-hearing (NH) and hearing-impaired (HI) listeners were also tested on the same tasks. STM detection performance was best in NH subjects, followed by HI subjects. On average, CI subjects showed poorest performance, but some CI subjects showed high levels of STM detection performance that was comparable to acoustic hearing. Significant correlations were found between STM detection performance and speech identification performance in quiet and in noise. In order to understand the relative contribution of spectral and temporal modulation cues to speech perception abilities for CI users, spectral and temporal modulation detection was performed separately and related to STM detection and speech perception performance. The results suggest that that slow spectral modulation rather than slow temporal modulation may be important for determining speech perception capabilities for CI users. Lastly, test–retest reliability for STM detection was good with no learning. The present study demonstrates that STM detection may be a useful tool to evaluate the ability of CI sound processing strategies to deliver clinically pertinent acoustic modulation information. PMID:26485715

Estimation of detection thresholds for redirected walking techniques.

PubMed

Steinicke, Frank; Bruder, Gerd; Jerald, Jason; Frenz, Harald; Lappe, Markus

2010-01-01

In immersive virtual environments (IVEs), users can control their virtual viewpoint by moving their tracked head and walking through the real world. Usually, movements in the real world are mapped one-to-one to virtual camera motions. With redirection techniques, the virtual camera is manipulated by applying gains to user motion so that the virtual world moves differently than the real world. Thus, users can walk through large-scale IVEs while physically remaining in a reasonably small workspace. In psychophysical experiments with a two-alternative forced-choice task, we have quantified how much humans can unknowingly be redirected on physical paths that are different from the visually perceived paths. We tested 12 subjects in three different experiments: (E1) discrimination between virtual and physical rotations, (E2) discrimination between virtual and physical straightforward movements, and (E3) discrimination of path curvature. In experiment E1, subjects performed rotations with different gains, and then had to choose whether the visually perceived rotation was smaller or greater than the physical rotation. In experiment E2, subjects chose whether the physical walk was shorter or longer than the visually perceived scaled travel distance. In experiment E3, subjects estimate the path curvature when walking a curved path in the real world while the visual display shows a straight path in the virtual world. Our results show that users can be turned physically about 49 percent more or 20 percent less than the perceived virtual rotation, distances can be downscaled by 14 percent and upscaled by 26 percent, and users can be redirected on a circular arc with a radius greater than 22 m while they believe that they are walking straight.

Collaborative Filtering for Brain-Computer Interaction Using Transfer Learning and Active Class Selection

PubMed Central

Wu, Dongrui; Lance, Brent J.; Parsons, Thomas D.

2013-01-01

Brain-computer interaction (BCI) and physiological computing are terms that refer to using processed neural or physiological signals to influence human interaction with computers, environment, and each other. A major challenge in developing these systems arises from the large individual differences typically seen in the neural/physiological responses. As a result, many researchers use individually-trained recognition algorithms to process this data. In order to minimize time, cost, and barriers to use, there is a need to minimize the amount of individual training data required, or equivalently, to increase the recognition accuracy without increasing the number of user-specific training samples. One promising method for achieving this is collaborative filtering, which combines training data from the individual subject with additional training data from other, similar subjects. This paper describes a successful application of a collaborative filtering approach intended for a BCI system. This approach is based on transfer learning (TL), active class selection (ACS), and a mean squared difference user-similarity heuristic. The resulting BCI system uses neural and physiological signals for automatic task difficulty recognition. TL improves the learning performance by combining a small number of user-specific training samples with a large number of auxiliary training samples from other similar subjects. ACS optimally selects the classes to generate user-specific training samples. Experimental results on 18 subjects, using both nearest neighbors and support vector machine classifiers, demonstrate that the proposed approach can significantly reduce the number of user-specific training data samples. This collaborative filtering approach will also be generalizable to handling individual differences in many other applications that involve human neural or physiological data, such as affective computing. PMID:23437188

Reductions in biomarkers of exposure (BoE) to harmful or potentially harmful constituents (HPHCs) following partial or complete substitution of cigarettes with electronic cigarettes in adult smokers.

PubMed

O'Connell, Grant; Graff, Donald W; D'Ruiz, Carl D

2016-07-01

Changes in fifteen urine, blood and exhaled breath BoEs of HPHCs representing classes of compounds reported by FDA to be significant contributors to smoking-associated disease risks were measured in 105 clinical-confined subjects following randomization and a five-day forced-switch from usual brand conventional combustible cigarettes to: (i) exclusive commercial e-cigarette use; (ii) dual-use of commercial e-cigarettes and the subject's usual cigarette brand; or (iii) discontinued use of all tobacco or nicotine products. Levels of urinary biomarkers in subjects that completely substituted their usual cigarette with e-cigarettes were significantly lower (29-95%) after 5 days. Percent reductions in eight of nine urinary BoEs were indistinguishable to smokers who had quit smoking, except for nicotine equivalents, which declined by 25-40%. Dual users who halved self-reported daily cigarette consumption with e-cigarettes exhibited reductions (7-38%) in eight of nine urinary biomarkers, but had increase (1-20%) in nicotine equivalents. Reductions were broadly proportional to the reduced numbers of cigarettes smoked. Dual user urinary nicotine equivalents were slightly higher, but not statistically significant. After 5 days, blood nicotine biomarker levels were lower in the cessation (75-96%) and exclusive use groups (11-83%); with dual users experiencing no significant reductions. All subjects experienced significant decreases in exhaled CO. Decreases in the cessation and exclusive groups ranged from 88-89% and 27-32% in dual users. Exhaled NO increased in the cessation and exclusive groups (46-63% respectively), whereas the dual users experienced minimal changes. Overall, smokers who completely or partially substituted conventional cigarettes with e-cigarettes over five days, experienced reductions in HPHCs.

76 FR 31010 - Montreal, Maine & Atlantic Railway, Ltd.-Trackage Rights Exemption-Maine Northern Railway Company

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-27

... rights to Montreal, Maine & Atlantic Railway, Ltd. (MMA) over approximately 151 miles of rail line owned... Madawaska, ME (Subject Trackage).\\1\\ MMA states that, as of January 14, 2011, it sold the Subject Trackage... operate these lines. \\1\\ The Subject Trackage was formerly part of the Madawaska Subdivision of MMA...

Quantitative analysis of task selection for brain-computer interfaces

NASA Astrophysics Data System (ADS)

Llera, Alberto; Gómez, Vicenç; Kappen, Hilbert J.

2014-10-01

Objective. To assess quantitatively the impact of task selection in the performance of brain-computer interfaces (BCI). Approach. We consider the task-pairs derived from multi-class BCI imagery movement tasks in three different datasets. We analyze for the first time the benefits of task selection on a large-scale basis (109 users) and evaluate the possibility of transferring task-pair information across days for a given subject. Main results. Selecting the subject-dependent optimal task-pair among three different imagery movement tasks results in approximately 20% potential increase in the number of users that can be expected to control a binary BCI. The improvement is observed with respect to the best task-pair fixed across subjects. The best task-pair selected for each subject individually during a first day of recordings is generally a good task-pair in subsequent days. In general, task learning from the user side has a positive influence in the generalization of the optimal task-pair, but special attention should be given to inexperienced subjects. Significance. These results add significant evidence to existing literature that advocates task selection as a necessary step towards usable BCIs. This contribution motivates further research focused on deriving adaptive methods for task selection on larger sets of mental tasks in practical online scenarios.

Cephalometrically assessing the validity of superior, middle and inferior tragus points on ala-tragus line while establishing the occlusal plane in edentulous patient

PubMed Central

Thombare, Ram

2013-01-01

PURPOSE The purpose of this study was to decide the most appropriate point on tragus to be used as a reference point at time of marking ala tragus line while establishing occlusal plane. MATERIALS AND METHODS The data was collected in two groups of subjects: 1) Dentulous 2) Edentulous group having sample size of 30 for each group with equal gender distribution (15 males, 15 females each). Downs analysis was used for base value. Lateral cephalographs were taken for all selected subjects. Three points were marked on tragus as Superior (S), Middle (M), and Inferior (I) and were joined with ala (A) of the nose to form ala-tragus lines. The angle formed by each line (SA plane, MA plane, IA plane) with Frankfort Horizontal (FH) plane was measured by using custom made device and modified protractor in all dentulous and edentulous subjects. Also, in dentulous subjects angle between Frankfort Horizontal plane and natural occlusal plane was measured. The measurements obtained were subjected to the following statistical tests; descriptive analysis, Student's unpaired t-test and Pearson's correlation coefficient. RESULTS The results demonstrated, the mean angle COO (cant of occlusal plane) as 9.76°, inferior point on tragus had given the mean angular value of IFH [Angle between IA plane (plane formed by joining inferior point-I on tragus and ala of nose- A) and FH plane) as 10.40° and 10.56° in dentulous and edentulous subjects respectively which was the closest value to the angle COO and was comparable with the values of angle COO value in Downs analysis. Angulations of ala-tragus line marked from inferior point with occlusal plane in dentulous subject had given the smallest value 2.46° which showed that this ala-tragus line was nearly parallel to occlusal plane. CONCLUSION The inferior point marked on tragus is the most appropriate point for marking ala-tragus line. PMID:23508068

Memory deficits in abstinent MDMA (ecstasy) users: neuropsychological evidence of frontal dysfunction.

PubMed

Quednow, Boris B; Jessen, Frank; Kuhn, Kai-Uwe; Maier, Wolfgang; Daum, Irene; Wagner, Michael

2006-05-01

Chronic administration of the common club drug 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) is associated with long-term depletion of serotonin (5-HT) and loss of 5-HT axons in the brains of rodents and non-human primates, and evidence suggests that recreational MDMA consumption may also affect the human serotonergic system. Moreover, it was consistently shown that abstinent MDMA users have memory deficits. Recently, it was supposed that these deficits are an expression of a temporal or rather hippocampal dysfunction caused by the serotonergic neurotoxicity of MDMA. The aim of this study is to examine the memory deficits of MDMA users neuropsychologically in order to evaluate the role of different brain regions. Nineteen male abstinent MDMA users, 19 male abstinent cannabis users and 19 male drug-naive control subjects were examined with a German version of the Rey Auditory Verbal Learning Test (RAVLT). MDMA users showed widespread and marked verbal memory deficits, compared to drug-naive controls as well as compared to cannabis users, whereas cannabis users did not differ from control subjects in their memory performance. MDMA users revealed impairments in learning, consolidation, recall and recognition. In addition, they also showed a worse recall consistency and strong retroactive interference whereby both measures were previously associated with frontal lobe function. There was a significant correlation between memory performance and the amount of MDMA taken. These results suggest that the memory deficits of MDMA users are not only the result of a temporal or hippocampal dysfunction, but also of a dysfunction of regions within the frontal cortex.

MeV+R: using MeV as a graphical user interface for Bioconductor applications in microarray analysis

PubMed Central

Chu, Vu T; Gottardo, Raphael; Raftery, Adrian E; Bumgarner, Roger E; Yeung, Ka Yee

2008-01-01

We present MeV+R, an integration of the JAVA MultiExperiment Viewer program with Bioconductor packages. This integration of MultiExperiment Viewer and R is easily extensible to other R packages and provides users with point and click access to traditionally command line driven tools written in R. We demonstrate the ability to use MultiExperiment Viewer as a graphical user interface for Bioconductor applications in microarray data analysis by incorporating three Bioconductor packages, RAMA, BRIDGE and iterativeBMA. PMID:18652698

Web-Based Media Contents Editor for UCC Websites

NASA Astrophysics Data System (ADS)

Kim, Seoksoo

The purpose of this research is to "design web-based media contents editor for establishing UCC(User Created Contents)-based websites." The web-based editor features user-oriented interfaces and increased convenience, significantly different from previous off-line editors. It allows users to edit media contents online and can be effectively used for online promotion activities of enterprises and organizations. In addition to development of the editor, the research aims to support the entry of enterprises and public agencies to the online market by combining the technology with various UCC items.

Image of a line is not shrunk but neglected. Absence of crossover in unilateral spatial neglect.

PubMed

Ishiai, Sumio; Koyama, Yasumasa; Nakano, Naomi; Seki, Keiko; Nishida, Yoichiro; Hayashi, Kazuko

2004-01-01

Patients with left unilateral spatial neglect following right hemisphere lesions usually err rightward when bisecting a horizontal line. For very short lines (e.g. 25 mm), however, leftward errors or seemingly 'right' neglect is often observed. To explain this paradox of crossover in the direction of errors, rather complicated models have been introduced as to the distribution of attention. Neglect may be hypothesized to occur in representational process of a line or estimation of the midpoint on the formed image, or both. We devised a line image task using a computer display with a touch panel and approached the representational image of a line to be bisected. Three patients with typical left neglect were presented with a line and forced to see its whole extent with cueing to the left endpoint. After disappearance of the line, they pointed to the right endpoint, the left endpoint, or the subjective midpoint according to their representational image. The line image between the reproduced right and left endpoints was appropriately formed for the 200 mm lines. However, the images for the shorter 25 and 100 mm lines were longer than the physical lengths with overextension to the left side. These results proved the context effect that short lines may be perceived longer when they are presented in combination with longer lines. One of our patients had an extensive lesion that involved the frontal, temporal, and parietal lobes, and the other two had a lesion restricted to the posterior right hemisphere. The image for a fully perceived line may be represented far enough into left space even when left neglect occurs after a lesion that involves the right parietal lobe. The patients with neglect placed the subjective midpoint rightward from the centre of the stimulus line for the 100 and 200 mm lines and leftward for the 25 mm lines. This crossover of bisection errors disappeared when the displacement of the subjective midpoint was measured from the centre of the representational line image. Left neglect may occur consistently in estimation of the subjective midpoint on the representational image, which may be explained by a simple rightward bias of attentional distribution.

Simultaneous operation of two soft x-ray free-electron lasers driven by one linear accelerator

DOE PAGES

Faatz, B.; Plönjes, E.; Ackermann, S.; ...

2016-06-20

Extreme-ultraviolet to x-ray free-electron lasers (FELs) in operation for scientific applications are up to now single-user facilities. While most FELs generate around 100 photon pulses per second, FLASH at DESY can deliver almost two orders of magnitude more pulses in this time span due to its superconducting accelerator technology. This makes the facility a prime candidate to realize the next step in FELs—dividing the electron pulse trains into several FEL lines and delivering photon pulses to several users at the same time. Hence, FLASH has been extended with a second undulator line and self-amplified spontaneous emission (SASE) is demonstrated inmore » both FELs simultaneously. Here, FLASH can now deliver MHz pulse trains to two user experiments in parallel with individually selected photon beam characteristics. First results of the capabilities of this extension are shown with emphasis on independent variation of wavelength, repetition rate, and photon pulse length.« less

Line drawing titled 'TDRS Spacecraft On-Orbit Configuration'

NASA Technical Reports Server (NTRS)

1988-01-01

Line drawing titled 'TDRS Spacecraft On-Orbit Configuration' identifies the various tracking and data relay satellite (TDRS) components (solar arrays, C-Band antenna, K-Band antenna, space ground link (SGL) antenna, single access antennas, multiple access antenna, omni antenna, solar sail). A TDRS will be deployed during the STS-26 mission. Including the space shuttle, the TDRS will be equipped to support up to 26 user spacecraft simultaneously. It will provide two types of service: 1) multiple access which can relay data from as many as 20 low data rate (100 bits per second to 50 kilobits per second) user satellites simultaneously and; 2) single access which will provide two high data rate (to 300 megabits per second) communication relays. The TDRS is three-axis stabilizrd with the body fixed antennas pointing constantly at the Earth while the solar arrays track the Sun. TDR satellites do no processing of user traffic in either direction. Rather, they operate as 'bent pipe' repeaters,

Scheduler software for tracking and data relay satellite system loading analysis: User manual and programmer guide

NASA Technical Reports Server (NTRS)

Craft, R.; Dunn, C.; Mccord, J.; Simeone, L.

1980-01-01

A user guide and programmer documentation is provided for a system of PRIME 400 minicomputer programs. The system was designed to support loading analyses on the Tracking Data Relay Satellite System (TDRSS). The system is a scheduler for various types of data relays (including tape recorder dumps and real time relays) from orbiting payloads to the TDRSS. Several model options are available to statistically generate data relay requirements. TDRSS time lines (representing resources available for scheduling) and payload/TDRSS acquisition and loss of sight time lines are input to the scheduler from disk. Tabulated output from the interactive system includes a summary of the scheduler activities over time intervals specified by the user and overall summary of scheduler input and output information. A history file, which records every event generated by the scheduler, is written to disk to allow further scheduling on remaining resources and to provide data for graphic displays or additional statistical analysis.

Math Description Engine Software Development Kit

NASA Technical Reports Server (NTRS)

Shelton, Robert O.; Smith, Stephanie L.; Dexter, Dan E.; Hodgson, Terry R.

2010-01-01

The Math Description Engine Software Development Kit (MDE SDK) can be used by software developers to make computer-rendered graphs more accessible to blind and visually-impaired users. The MDE SDK generates alternative graph descriptions in two forms: textual descriptions and non-verbal sound renderings, or sonification. It also enables display of an animated trace of a graph sonification on a visual graph component, with color and line-thickness options for users having low vision or color-related impairments. A set of accessible graphical user interface widgets is provided for operation by end users and for control of accessible graph displays. Version 1.0 of the MDE SDK generates text descriptions for 2D graphs commonly seen in math and science curriculum (and practice). The mathematically rich text descriptions can also serve as a virtual math and science assistant for blind and sighted users, making graphs more accessible for everyone. The MDE SDK has a simple application programming interface (API) that makes it easy for programmers and Web-site developers to make graphs accessible with just a few lines of code. The source code is written in Java for cross-platform compatibility and to take advantage of Java s built-in support for building accessible software application interfaces. Compiled-library and NASA Open Source versions are available with API documentation and Programmer s Guide at http:/ / prim e.jsc.n asa. gov.

On-line atomic data access

NASA Astrophysics Data System (ADS)

Schultz, David R.; Nash, Jeffrey K.

1996-07-01

The need for atomic data is one which continues to expand in a wide variety of applications including fusion energy, astrophysics, laser-produced plasma research, and plasma processing. Modern computer database and communications technology enables this data to be placed on-line and obtained by users over the INTERNET. Presented here is a summary of the observations and conclusions regarding such on-line atomic data access derived from a forum held at the Tenth APS Topical Conference on Atomic Processes in Plasmas.

Analysis of Relative Parallelism Between Hamular-Incisive-Papilla Plane and Campers Plane in Edentulous Subjects: A Comparative Study.

PubMed

Tambake, Deepti; Shetty, Shilpa; Satish Babu, C L; Fulari, Sangamesh G

2014-12-01

The study was undertaken to evaluate the parallelism between hamular-incisive-papilla plane (HIP) and the Campers plane. And to determine which part of the posterior reference of the tragus i.e., the superior, middle or the inferior of the Camper's plane is parallel to HIP using digital lateral cephalograms. Fifty edentulous subjects with well formed ridges were selected for the study. The master casts were obtained using the standard selective pressure impression procedure. On the deepest point of the hamular notches and the centre of the incisive papilla stainless steel spherical bearings were glued to the cast at the marked points. The study templates were fabricated with autopolymerizing acrylic resin. The subjects were prepared for the lateral cephalograms. Stainless steel spherical bearings were adhered to the superior, middle, inferior points of the tragus of the ear and inferior border of the ala of the nose using surgical adhesive tape. The subjects with study templates were subjected to lateral cephalograms. Cephalometric tracings were done using Autocad 2010 software. Lines were drawn connecting the incisive papilla and hamular notch and the stainless steel spherical bearings placed on the superior, middle and inferior points on the tragus and the ala of the nose i.e., the Campers line S, Campers line M, Campers line I. The angles between the three Camper's line and the HIP were measured and recorded. Higher mean angulation was recorded in Campers line S -HIP (8.03) followed by Campers line M-HIP (4.60). Campers line I-HIP recorded the least angulation (3.80). The HIP is parallel to the Camper's plane. The Camper's plane formed with the posterior reference point as inferior point of the tragus is relatively parallel to the HIP.

Robust camera calibration for sport videos using court models

NASA Astrophysics Data System (ADS)

Farin, Dirk; Krabbe, Susanne; de With, Peter H. N.; Effelsberg, Wolfgang

2003-12-01

We propose an automatic camera calibration algorithm for court sports. The obtained camera calibration parameters are required for applications that need to convert positions in the video frame to real-world coordinates or vice versa. Our algorithm uses a model of the arrangement of court lines for calibration. Since the court model can be specified by the user, the algorithm can be applied to a variety of different sports. The algorithm starts with a model initialization step which locates the court in the image without any user assistance or a-priori knowledge about the most probable position. Image pixels are classified as court line pixels if they pass several tests including color and local texture constraints. A Hough transform is applied to extract line elements, forming a set of court line candidates. The subsequent combinatorial search establishes correspondences between lines in the input image and lines from the court model. For the succeeding input frames, an abbreviated calibration algorithm is used, which predicts the camera parameters for the new image and optimizes the parameters using a gradient-descent algorithm. We have conducted experiments on a variety of sport videos (tennis, volleyball, and goal area sequences of soccer games). Video scenes with considerable difficulties were selected to test the robustness of the algorithm. Results show that the algorithm is very robust to occlusions, partial court views, bad lighting conditions, or shadows.

Usability testing of a prototype multi-user telehealth kiosk.

PubMed

Courtney, Karen L; Matthews, Judith T; McMillan, Julie M; Person Mecca, Laurel; Smailagic, Asim; Siewiorek, Daniel

2015-01-01

The overall purpose of this study was to learn how community-dwelling older adults would interact with our prototype multi-user telehealth kiosk and their views about its usability. Seven subjects participated in laboratory-based usability sessions to evaluate the physical design, appearance, functionality and perceived ease of use of a multi-user telehealth kiosk prototype. During usability testing participants recommended 18 new features (29% of comments), identified 15 software errors (23% of comments) and 29 user interface errors (47% of comments).

Evaluation of renal function change during first-line tyrosine kinase inhibitor therapy for metastatic renal cell carcinoma.

PubMed

Ishihara, Hiroki; Kondo, Tsunenori; Fukuda, Hironori; Yoshida, Kazuhiko; Omae, Kenji; Takagi, Toshio; Iizuka, Junpei; Kobayashi, Hirohito; Tanabe, Kazunari

2017-12-01

The change in renal function induced by first-line tyrosine kinase inhibitor therapy for metastatic renal cell carcinoma remains unclear. One hundred and thirty-four patients were evaluated. Sunitinib (SU) and sorafenib (SO) were administered to 91 (67.9%) and 43 (32.1%) patients, respectively. The change in estimated glomerular filtration rate (ΔeGFR) was calculated as [(eGFR at each time point - pre-treatment eGFR)/pre-treatment eGFR] × 100. ΔeGFR was compared between SU- and SO users using a mixed-effects model for repeated measures data with two or greater. Additionally, predictors for ΔeGFR ≤ -10% at 6 months after therapy initiation were evaluated using multivariate logistic regression analysis. Throughout the 24 months after therapy initiation, ΔeGFR was negatively greater in SU users, compared with that in SO users (P < 0.0001). In SU users, renal dysfunction was observed regardless of pre-treatment chronic kidney disease (CKD) status, whereas the magnitude of renal dysfunction was milder in SO users. In SO users without pre-treatment CKD, renal function did not significantly deteriorate. Moreover, ΔeGFR ≤ -10% was more frequently observed in SU users after 3 months (P = 0.0121) and 6 months (P = 0.0009). Finally, SU usage was an independent predictor for ΔeGFR ≤ -10% at 6 months (odds ratio 8.87, P = 0.0053), along with pre-treatment hypertension (odds ratio 4.69, P = 00072). Deterioration of renal function was stronger with SU than SO. During SU therapy, renal function should be monitored and pre-treatment kidney function should be taken into consideration for therapy selection. © The Author 2017. Published by Oxford University Press.

A Multimodal Deep Log-Based User Experience (UX) Platform for UX Evaluation

PubMed Central

Ali Khan, Wajahat; Hur, Taeho; Muhammad Bilal, Hafiz Syed; Ul Hassan, Anees; Lee, Sungyoung

2018-01-01

The user experience (UX) is an emerging field in user research and design, and the development of UX evaluation methods presents a challenge for both researchers and practitioners. Different UX evaluation methods have been developed to extract accurate UX data. Among UX evaluation methods, the mixed-method approach of triangulation has gained importance. It provides more accurate and precise information about the user while interacting with the product. However, this approach requires skilled UX researchers and developers to integrate multiple devices, synchronize them, analyze the data, and ultimately produce an informed decision. In this paper, a method and system for measuring the overall UX over time using a triangulation method are proposed. The proposed platform incorporates observational and physiological measurements in addition to traditional ones. The platform reduces the subjective bias and validates the user’s perceptions, which are measured by different sensors through objectification of the subjective nature of the user in the UX assessment. The platform additionally offers plug-and-play support for different devices and powerful analytics for obtaining insight on the UX in terms of multiple participants. PMID:29783712

Quality versus intelligibility: studying human preferences for American Sign Language video

NASA Astrophysics Data System (ADS)

Ciaramello, Frank M.; Hemami, Sheila S.

2011-03-01

Real-time videoconferencing using cellular devices provides natural communication to the Deaf community. For this application, compressed American Sign Language (ASL) video must be evaluated in terms of the intelligibility of the conversation and not in terms of the overall aesthetic quality of the video. This work presents a paired comparison experiment to determine the subjective preferences of ASL users in terms of the trade-off between intelligibility and quality when varying the proportion of the bitrate allocated explicitly to the regions of the video containing the signer. A rate-distortion optimization technique, which jointly optimizes a quality criteria and an intelligibility criteria according to a user-specified parameter, generates test video pairs for the subjective experiment. Experimental results suggest that at sufficiently high bitrates, all users prefer videos in which the non-signer regions in the video are encoded with some nominal rate. As the total encoding bitrate decreases, users generally prefer video in which a greater proportion of the rate is allocated to the signer. The specific operating points preferred in the quality-intelligibility trade-off vary with the demographics of the users.

Development of Very Long Baseline Interferometry (VLBI) techniques in New Zealand: Array simulation, image synthesis and analysis

NASA Astrophysics Data System (ADS)

Weston, S. D.

2008-04-01

This thesis presents the design and development of a process to model Very Long Base Line Interferometry (VLBI) aperture synthesis antenna arrays. In line with the Auckland University of Technology (AUT) Institute for Radiophysics and Space Research (IRSR) aims to develop the knowledge, skills and experience within New Zealand, extensive use of existing radio astronomical software has been incorporated into the process namely AIPS (Astronomical Imaging Processing System), MIRIAD (a radio interferometry data reduction package) and DIFMAP (a program for synthesis imaging of visibility data from interferometer arrays of radio telescopes). This process has been used to model various antenna array configurations for two proposed New Zealand sites for antenna in a VLBI array configuration with existing Australian facilities and a passable antenna at Scott Base in Antarctica; and the results are presented in an attempt to demonstrate the improvement to be gained by joint trans-Tasman VLBI observation. It is hoped these results and process will assist the planning and placement of proposed New Zealand radio telescopes for cooperation with groups such as the Australian Long Baseline Array (LBA), others in the Pacific Rim and possibly globally; also potential future involvement of New Zealand with the SKA. The developed process has also been used to model a phased building schedule for the SKA in Australia and the addition of two antennas in New Zealand. This has been presented to the wider astronomical community via the Royal Astronomical Society of New Zealand Journal, and is summarized in this thesis with some additional material. A new measure of quality ("figure of merit") for comparing the original model image and final CLEAN images by utilizing normalized 2-D cross correlation is evaluated as an alternative to the existing subjective visual operator image comparison undertaken to date by other groups. This new unit of measure is then used ! in the presentation of the results to provide a quantative comparison of the different array configurations modelled. Included in the process is the development of a new antenna array visibility program which was based on a Perl code script written by Prof Steven Tingay to plot antenna visibilities for the Australian Square Kilometre Array (SKA) proposal. This has been expanded and improved removing the hard coded fixed assumptions for the SKA configuration, providing a new useful and flexible program for the wider astronomical community. A prototype user interface using html/cgi/perl was developed for the process so that the underlying software packages can be served over the web to a user via an internet browser. This was used to demonstrate how easy it is to provide a friendlier interface compared to the existing cumbersome and difficult command line driven interfaces (although the command line can be retained for more experienced users).

Gender Differences between Graphical User Interfaces and Command Line Interfaces in Computer Instruction.

ERIC Educational Resources Information Center

Barker, Dan L.

This study focused primarily on two types of computer interfaces and the differences in academic performance that resulted from their use; it was secondarily designed to examine gender differences that may have existed before and after any change in interface. Much of the basic research in computer use was conducted with command line interface…

On-Line Analysis of Southern FIA Data

Treesearch

Michael P. Spinney; Paul C. Van Deusen; Francis A. Roesch

2006-01-01

The Southern On-Line Estimator (SOLE) is a web-based FIA database analysis tool designed with an emphasis on modularity. The Java-based user interface is simple and intuitive to use and the R-based analysis engine is fast and stable. Each component of the program (data retrieval, statistical analysis and output) can be individually modified to accommodate major...

Impact of Truck Loading on Design and Analysis of Asphaltic Pavement Structures : Phase II

DOT National Transportation Integrated Search

2011-02-01

In this study, Schaperys nonlinear viscoelastic constitutive model is implemented into the commercial finite element (FE) software ABAQUS via user defined subroutine (user material, or UMAT) to analyze asphalt pavement subjected to heavy truck loa...

TRUST: TDRSS Resource User Support Tool

NASA Technical Reports Server (NTRS)

Sparn, Thomas P.; Gablehouse, R. Daniel

1991-01-01

TRUST-TDRSS (Tracking Data and Relay Satellite System) Resource User Support Tool is presented in the form of the viewgraphs. The following subject areas are covered: TRUST development cycle; the TRUST system; scheduling window; ODM/GCMR window; TRUST architecture; surpass; and summary.

Characteristics of Vocal Fold Vibrations in Vocally Healthy Subjects: Analysis with Multi-Line Kymography

ERIC Educational Resources Information Center

Yamauchi, Akihito; Imagawa, Hiroshi; Sakakibara, Ken-Ichi; Yokonishi, Hisayuki; Nito, Takaharu; Yamasoba, Tatsuya; Tayama, Niro

2014-01-01

Purpose: In this study, the authors aimed to analyze longitudinal data from high-speed digital images in normative subjects using multi-line kymography. Method: Vocally healthy subjects were divided into young (9 men and 17 women; M[subscript age] = 27 years) and older groups (8 men and 12 women; M[subscript age] = 73 years). From high-speed…

Graphical user interfaces for symbol-oriented database visualization and interaction

NASA Astrophysics Data System (ADS)

Brinkschulte, Uwe; Siormanolakis, Marios; Vogelsang, Holger

1997-04-01

In this approach, two basic services designed for the engineering of computer based systems are combined: a symbol-oriented man-machine-service and a high speed database-service. The man-machine service is used to build graphical user interfaces (GUIs) for the database service; these interfaces are stored using the database service. The idea is to create a GUI-builder and a GUI-manager for the database service based upon the man-machine service using the concept of symbols. With user-definable and predefined symbols, database contents can be visualized and manipulated in a very flexible and intuitive way. Using the GUI-builder and GUI-manager, a user can build and operate its own graphical user interface for a given database according to its needs without writing a single line of code.

Unemployment, Drug Use, and HIV Risk among American Indian and Alaska Native Drug Users.

ERIC Educational Resources Information Center

Reynolds, Grace L.; Fisher, Dennis G.; Estrada, Antonio L.; Trotter, Robert

2000-01-01

Study and 6-month followup of 3,622 drug users in Tucson, Flagstaff, and Anchorage found that American Indian and Alaska Native drug users were younger, less educated, and less likely to be employed than non-Native subjects. Individuals employed at intake or followup had lower levels of HIV risk factors: injection drug use and needle sharing.…

Network Control Center User Planning System (NCC UPS)

NASA Astrophysics Data System (ADS)

Dealy, Brian

1991-09-01

NCC UPS is presented in the form of the viewgraphs. The following subject areas are covered: UPS overview; NCC UPS role; major NCC UPS functional requirements; interactive user access levels; UPS interfaces; interactive user subsystem; interface navigation; scheduling screen hierarchy; interactive scheduling input panels; autogenerated schedule request panel; schedule data tabular display panel; schedule data graphic display panel; graphic scheduling aid design; and schedule data graphic display.

Network Control Center User Planning System (NCC UPS)

NASA Technical Reports Server (NTRS)

Dealy, Brian

1991-01-01

NCC UPS is presented in the form of the viewgraphs. The following subject areas are covered: UPS overview; NCC UPS role; major NCC UPS functional requirements; interactive user access levels; UPS interfaces; interactive user subsystem; interface navigation; scheduling screen hierarchy; interactive scheduling input panels; autogenerated schedule request panel; schedule data tabular display panel; schedule data graphic display panel; graphic scheduling aid design; and schedule data graphic display.

Current and former marijuana use: preliminary findings of a longitudinal study of effects on IQ in young adults

PubMed Central

Fried, Peter; Watkinson, Barbara; James, Deborah; Gray, Robert

2002-01-01

Background Assessing marijuana's impact on intelligence quotient (IQ) has been hampered by a lack of evaluation of subjects before they begin to use this substance. Using data from a group of young people whom we have been following since birth, we examined IQ scores before, during and after cessation of regular marijuana use to determine any impact of the drug on this measure of cognitive function. Methods We determined marijuana use for seventy 17- to 20-year-olds through self-reporting and urinalysis. IQ difference scores were calculated by subtracting each person's IQ score at 9–12 years (before initiation of drug use) from his or her score at 17–20 years. We then compared the difference in IQ scores of current heavy users (at least 5 joints per week), current light users (less than 5 joints per week), former users (who had not smoked regularly for at least 3 months) and non-users (who never smoked more than once per week and no smoking in the past two weeks). Results Current marijuana use was significantly correlated (p < 0.05) in a dose- related fashion with a decline in IQ over the ages studied. The comparison of the IQ difference scores showed an average decrease of 4.1 points in current heavy users (p < 0.05) compared to gains in IQ points for light current users (5.8), former users (3.5) and non-users (2.6). Interpretation Current marijuana use had a negative effect on global IQ score only in subjects who smoked 5 or more joints per week. A negative effect was not observed among subjects who had previously been heavy users but were no longer using the substance. We conclude that marijuana does not have a long-term negative impact on global intelligence. Whether the absence of a residual marijuana effect would also be evident in more specific cognitive domains such as memory and attention remains to be ascertained. PMID:11949984

Bone-anchored Hearing Aids: correlation between pure-tone thresholds and outcome in three user groups.

PubMed

Pfiffner, Flurin; Kompis, Martin; Stieger, Christof

2009-10-01

To investigate correlations between preoperative hearing thresholds and postoperative aided thresholds and speech understanding of users of Bone-anchored Hearing Aids (BAHA). Such correlations may be useful to estimate the postoperative outcome with BAHA from preoperative data. Retrospective case review. Tertiary referral center. : Ninety-two adult unilaterally implanted BAHA users in 3 groups: (A) 24 subjects with a unilateral conductive hearing loss, (B) 38 subjects with a bilateral conductive hearing loss, and (C) 30 subjects with single-sided deafness. Preoperative air-conduction and bone-conduction thresholds and 3-month postoperative aided and unaided sound-field thresholds as well as speech understanding using German 2-digit numbers and monosyllabic words were measured and analyzed. Correlation between preoperative air-conduction and bone-conduction thresholds of the better and of the poorer ear and postoperative aided thresholds as well as correlations between gain in sound-field threshold and gain in speech understanding. Aided postoperative sound-field thresholds correlate best with BC threshold of the better ear (correlation coefficients, r2 = 0.237 to 0.419, p = 0.0006 to 0.0064, depending on the group of subjects). Improvements in sound-field threshold correspond to improvements in speech understanding. When estimating expected postoperative aided sound-field thresholds of BAHA users from preoperative hearing thresholds, the BC threshold of the better ear should be used. For the patient groups considered, speech understanding in quiet can be estimated from the improvement in sound-field thresholds.

Study and response time for the visual recognition of 'similarity' and identity

NASA Technical Reports Server (NTRS)

Derks, P. L.; Bauer, T. M.

1974-01-01

Four subjects compared successively presented pairs of line patterns for a match between any lines in the pattern (similarity) and for a match between all lines (identity). The encoding or study times for pattern recognition from immediate memory and the latency in responses to comparison stimuli were examined. Qualitative differences within and between subjects were most evident in study times.

The effect of image sharpness on quantitative eye movement data and on image quality evaluation while viewing natural images

NASA Astrophysics Data System (ADS)

Vuori, Tero; Olkkonen, Maria

2006-01-01

The aim of the study is to test both customer image quality rating (subjective image quality) and physical measurement of user behavior (eye movements tracking) to find customer satisfaction differences in imaging technologies. Methodological aim is to find out whether eye movements could be quantitatively used in image quality preference studies. In general, we want to map objective or physically measurable image quality to subjective evaluations and eye movement data. We conducted a series of image quality tests, in which the test subjects evaluated image quality while we recorded their eye movements. Results show that eye movement parameters consistently change according to the instructions given to the user, and according to physical image quality, e.g. saccade duration increased with increasing blur. Results indicate that eye movement tracking could be used to differentiate image quality evaluation strategies that the users have. Results also show that eye movements would help mapping between technological and subjective image quality. Furthermore, these results give some empirical emphasis to top-down perception processes in image quality perception and evaluation by showing differences between perceptual processes in situations when cognitive task varies.

Charming Users into Scripting CIAO with Python

NASA Astrophysics Data System (ADS)

Burke, D. J.

2011-07-01

The Science Data Systems group of the Chandra X-ray Center provides a number of scripts and Python modules that extend the capabilities of CIAO. Experience in converting the existing scripts—written in a variety of languages such as bash, csh/tcsh, Perl and S-Lang—to Python, and conversations with users, led to the development of the ciao_contrib.runtool module. This allows users to easily run CIAO tools from Python scripts, and utilizes the metadata provided by the parameter-file system to create an API that provides the flexibility and safety guarantees of the command-line. The module is provided to the user community and is being used within our group to create new scripts.

LAMPAT and LAMPATNL User’s Manual

DTIC Science & Technology

2012-09-01

nonlinearity. These tools are implemented as subroutines in the finite element software ABAQUS . This user’s manual provides information on the proper...model either through the General tab of the Edit Job dialog box in Abaqus /CAE or the command line with user=( subroutine filename). Table 1...Selection of software product and subroutine . Static Analysis With Abaqus /Standard Dynamic Analysis With Abaqus /Explicit Linear, uncoupled

CIRCAL-2 - General-purpose on-line circuit design.

NASA Technical Reports Server (NTRS)

Dertouzos, M. L.; Jessel, G. P.; Stinger, J. R.

1972-01-01

CIRCAL-2 is a second-generation general-purpose on-line circuit-design program with the following main features: (1) multiple-analysis capability; (2) uniform and general data structures for handling text editing, network representations, and output results, regardless of analysis; (3) special techniques and structures for minimizing and controlling user-program interaction; (4) use of functionals for the description of hysteresis and heat effects; and (5) ability to define optimization procedures that 'replace' the user. The paper discusses the organization of CIRCAL-2, the aforementioned main features, and their consequences, such as a set of network elements and models general enough for most analyses and a set of functions tailored to circuit-design requirements. The presentation is descriptive, concentrating on conceptual rather than on program implementation details.

User interface user's guide for HYPGEN

NASA Technical Reports Server (NTRS)

Chiu, Ing-Tsau

1992-01-01

The user interface (UI) of HYPGEN is developed using Panel Library to shorten the learning curve for new users and provide easier ways to run HYPGEN for casual users as well as for advanced users. Menus, buttons, sliders, and type-in fields are used extensively in UI to allow users to point and click with a mouse to choose various available options or to change values of parameters. On-line help is provided to give users information on using UI without consulting the manual. Default values are set for most parameters and boundary conditions are determined by UI to further reduce the effort needed to run HYPGEN; however, users are free to make any changes and save it in a file for later use. A hook to PLOT3D is built in to allow graphics manipulation. The viewpoint and min/max box for PLOT3D windows are computed by UI and saved in a PLOT3D journal file. For large grids which take a long time to generate on workstations, the grid generator (HYPGEN) can be run on faster computers such as Crays, while UI stays at the workstation.

15 CFR 752.2 - Eligible activities.

Code of Federal Regulations, 2013 CFR

2013-01-01

...) Service activities. Exporting items subject to the EAR as spare and replacement parts for servicing or stocking. (2) End-user activities. Exporting and reexporting items subject to the EAR for use as capital equipment. (3) Distribution activities. Exporting and reexporting items subject to the EAR for the purpose...

15 CFR 752.2 - Eligible activities.

Code of Federal Regulations, 2014 CFR

2014-01-01

...) Service activities. Exporting items subject to the EAR as spare and replacement parts for servicing or stocking. (2) End-user activities. Exporting and reexporting items subject to the EAR for use as capital equipment. (3) Distribution activities. Exporting and reexporting items subject to the EAR for the purpose...

15 CFR 752.2 - Eligible activities.

Code of Federal Regulations, 2010 CFR

2010-01-01

...) Service activities. Exporting items subject to the EAR as spare and replacement parts for servicing or stocking. (2) End-user activities. Exporting and reexporting items subject to the EAR for use as capital equipment. (3) Distribution activities. Exporting and reexporting items subject to the EAR for the purpose...

15 CFR 752.2 - Eligible activities.

Code of Federal Regulations, 2012 CFR

2012-01-01

...) Service activities. Exporting items subject to the EAR as spare and replacement parts for servicing or stocking. (2) End-user activities. Exporting and reexporting items subject to the EAR for use as capital equipment. (3) Distribution activities. Exporting and reexporting items subject to the EAR for the purpose...

15 CFR 752.2 - Eligible activities.

Code of Federal Regulations, 2011 CFR

2011-01-01

...) Service activities. Exporting items subject to the EAR as spare and replacement parts for servicing or stocking. (2) End-user activities. Exporting and reexporting items subject to the EAR for use as capital equipment. (3) Distribution activities. Exporting and reexporting items subject to the EAR for the purpose...

[The comparative assessment of the vocal function in the professional voice users and non-occupational voice users in the late adulthood].

PubMed

Pavlikhin, O G; Romanenko, S G; Krasnikova, D I; Lesogorova, E V; Yakovlev, V S

The objective of the present study was to evaluate the clinical and functional condition of the voice apparatus in the elderly patients and to elaborate recommendations for the prevention of disturbances of the vocal function in the professional voice users. This comprehensive study involved 95 patients including the active professional voice users (n=48) and 45 non-occupational voice users at the age from 61 to 82 years with the employment history varying from 32 to 51 years. The study was designed to obtain the voice characteristics by means of the subjective auditory assessment, microlaryngoscopy, video laryngostroboscopy, determination of maximum phonation time (MPT), and computer-assisted acoustic analysis of the voice with the use of the MDVP Kay Pentaxy system. The level of anxiety of the patients was estimated based on the results of the HADS questionnaire study. It is concluded that the majority of the disturbances of the vocal function in the professional voice users have the functional nature. It is concluded that the method of neuro-muscular electrophonopedic stimulation (NMEPS) of laryngeal muscles is the method of choice for the diagnostics of the vocal function of the voice users in the late adulthood. It is recommended that the professional vocal load for such subjects should not exceed 12-14 hours per week. Rational psychotherapy must constitute an important component of the system of measures intended to support the working capacity of the voice users belonging to this age group.

Impaired Perception of Sensory Consonance and Dissonance in Cochlear Implant Users.

PubMed

Caldwell, Meredith T; Jiradejvong, Patpong; Limb, Charles J

2016-03-01

In light of previous research demonstrating poor pitch perception in cochlear implant (CI) users, we hypothesized that the presence of consonant versus dissonant chord accompaniment in real-world musical stimuli would not impact subjective assessment of degree of pleasantness in CI users. Consonance/dissonance are perceptual features of harmony resulting from pitch relationships between simultaneously presented musical notes. Generally, consonant sounds are perceived as pleasant and dissonant ones as unpleasant. CI users exhibit impairments in pitch perception, making music listening difficult and often unenjoyable. To our knowledge, consonance/dissonance perception has not been studied in the CI population. Twelve novel melodies were created for this study. By altering the harmonic structures of the accompanying chords, we created three permutations of varying dissonance for each melody (36 stimuli in all). Ten CI users and 12 NH listeners provided Likert scale ratings from -5 (very unpleasant) to +5 (very pleasant) for each of the stimuli. A two-way ANOVA showed main effects for Dissonance Level and Subject Type as well as a two-way interaction between the two. Pairwise comparisons indicated that NH stimuli pleasantness ratings decreased with increasing dissonance, whereas CI ratings did not. NH pleasantness ratings were consistently lower than CI ratings. For CI users, consonant versus dissonant chord accompaniment had no significant impact on whether a melody was considered pleasant or unpleasant. This finding may be partially responsible for the decreased enjoyment of many CI users during music perception and is another manifestation of impaired pitch perception in CI users.

Occupational concerns associated with regular use of microscope.

PubMed

Jain, Garima; Shetty, Pushparaja

2014-08-01

Microscope work can be strenuous both to the visual system and the musculoskeletal system. Lack of awareness or indifference towards health issues may result in microscope users becoming victim to many occupational hazards. Our objective was to understand the occupational problems associated with regular use of microscope, awareness regarding the hazards, attitude and practice of microscope users towards the problems and preventive strategies. a questionnaire based survey done on 50 professionals and technicians who used microscope regularly in pathology, microbiology, hematology and cytology laboratories. Sixty two percent of subjects declared that they were suffering from musculoskeletal problems, most common locations being neck and back. Maximum prevalence of musculoskeletal problems was noted in those using microscope for 11-15 years and for more than 30 h/week. Sixty two percent of subjects were aware of workplace ergonomics. Fifty six percent of microscope users took regular short breaks for stretching exercises and 58% took visual breaks every 15-30 min in between microscope use sessions. As many as 94% subjects reported some form of visual problem. Fourty four percent of microscope users felt stressed with long working hours on microscope. The most common occupational concerns of microscope users were musculoskeletal problems of neck and back regions, eye fatigue, aggravation of ametropia, headache, stress due to long working hours and anxiety during or after microscope use. There is an immediate need for increasing awareness about the various occupational hazards and their irreversible effects to prevent them.

Estimation and comparison of salivary immunoglobulin A levels in tobacco chewers, tobacco smokers and normal subjects.

PubMed

Doni, Bharati R; Patil, Santosh; Peerapur, Basavaraj V; Kadaganchi, Harish; Bhat, Kishore G

2013-06-01

To estimate the salivary immunoglobulin A (IgA) levels in tobacco chewers, tobacco smokers and normal subjects and to compare the salivary IgA levels among tobacco chewers and tobacco smokers. The study group consisted of 80 subjects (tobacco users), 40 tobacco chewers and 40 tobacco smokers. Unstimulated whole saliva was collected from all tobacco users and 40 healthy age- and gender-matched non-tobacco users as control group. The study and control groups were divided into four subgroups based on age range. Salivary IgA levels were estimated by single radial immunodiffusion assay (SRID). All data were analysed using statistical software and to compare the results in three groups, single-factor analysis of variance was applied. The mean salivary IgA level in control group was 16.76 ± 1.37 mg/dl (SD); in tobacco chewers it was 7.89 ± 0.61 mg/dl (SD) and in tobacco smokers it was 6.55 ± 0.99 mg/dl (SD). The salivary IgA levels were decreased in tobacco chewers and tobacco smokers compared with the controls. Among the tobacco users, tobacco smokers had much reduced salivary IgA levels compared to tobacco chewers. All of these results were highly significant (P<0.001). The present study showed that tobacco chewers and tobacco smokers had decreased salivary IgA levels and among tobacco users, tobacco smokers had much reduced salivary IgA levels compared to tobacco chewers in unstimulated whole saliva.

Subject to empowerment: the constitution of power in an educational program for health professionals.

PubMed

Juritzen, Truls I; Engebretsen, Eivind; Heggen, Kristin

2013-08-01

Empowerment and user participation represents an ideal of power with a strong position in the health sector. In this article we use text analysis to investigate notions of power in a program plan for health workers focusing on empowerment. Issues addressed include: How are relationships of power between users and helpers described in the program plan? Which notions of user participation are embedded in the plan? The analysis is based on Foucault's idea that power which is made subject to attempts of redistribution will re-emerge in other forms. How this happens, and with what consequences, is our analytical concern. The analysis is contrasted with 'snapshots' from everyday life in a nursing home. The program plan communicates empowerment as a democracy-building instrument that the users need. It is a tool for providing expert assistance to the user's self-help. User participation is made into a tool which is external to the user him-/herself. Furthermore, the analysis shows that the plan's image of empowerment presupposes an 'élite user' able to articulate personal needs and desires. This is not very applicable to the most vulnerable user groups, who thereby may end up in an even weaker position. By way of conclusion, we argue that an exchange of undesirable dominating paternalism for a desirable empowerment will not abolish power, but may result in more covert and subtle forms of power that are less open to criticism. The paper offers insights that will facilitate reflections on the premises for practising empowerment-oriented health care.

Altered subjective reward valuation among female heavy marijuana users.

PubMed

Hefner, Kathryn R; Starr, Mark J

2017-02-01

Maladaptive decision-making is a cardinal feature of drug use, contributing to ongoing use, and reflecting alterations in how drug users assess uncertain reward value. Accumulating evidence indicates the consequences of heavy marijuana use are worse for female versus male animals and humans, but research assessing sex differences in reward-related decision-making among marijuana users remains scarce. We examined sex differences in the subjective valuation of certain and uncertain rewards among heavy marijuana users (52; 26 male and 26 female) and controls (52; 26 male and 26 female). We offered male and female heavy marijuana users and controls monetary rewards of certain and uncertain (probabilistic) values. We measured how preferences for uncertain rewards varied by the objective value of those rewards, moderators of reward uncertainty, Marijuana Group and Sex. Men were more sensitive to changes in the objective value of uncertain rewards than women. However, this effect of Sex differed by Marijuana Group. Female heavy marijuana users were more sensitive to changes in uncertain reward value, particularly when the "stakes" were high (i.e., greater difference between potential uncertain rewards), than female controls. Female heavy marijuana users' sensitivity to changes in the value of high stakes uncertain rewards was comparable to male marijuana users and controls. In contrast, male marijuana users' sensitivity to changes in the value of high stakes uncertain rewards did not differ from male controls. These results suggest sex differences in sensitivity to high risk rewards may be one pathway contributing to severer consequences of heavy marijuana use among women. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Munich Music Questionnaire: adaptation into Brazilian Portuguese and application in cochlear implant users.

PubMed

Frederigue-Lopes, Natália Barreto; Bevilacqua, Maria Cecilia; Costa, Orozimbo Alves

2015-01-01

To translate the Munich Music Questionnaire (MUMU) to Brazilian Portuguese, to adapt it culturally, and to describe the results obtained among adult users of cochlear implant (CI). We translated the questionnaire to Brazilian Portuguese, reviewed the grammatical and idiomatic equivalences (back-translation), and adapted it from a linguistic and cultural perspective. The resulting version of this process was applied among adult CI users through direct interviews. The Brazilian Portuguese version of MUMU was applied to 19 adult CI users with postlingual hearing loss, who had been users of the device for at least one year. The answers to the questionnaire were analyzed by distribution of frequency and percentage of occurrence in each question. The results showed a decrease in the frequency of CI users that listen to music, comparing the period before hearing loss and after the CI. Regarding the role that music played in the life of each participant, the responses did not score change, so the music remained being an important factor in the life of the evaluated subjects, even after the CI. The subjective evaluation tool MUMU was translated and culturally adapted to the population studied. In Brazilian Portuguese, it was called Questionário de Música de Munique. The study showed its applicability in the daily monitoring of CI users, thus providing a profile of the activities related to music in everyday life.

Automated videography for residential communications

NASA Astrophysics Data System (ADS)

Kurtz, Andrew F.; Neustaedter, Carman; Blose, Andrew C.

2010-02-01

The current widespread use of webcams for personal video communication over the Internet suggests that opportunities exist to develop video communications systems optimized for domestic use. We discuss both prior and existing technologies, and the results of user studies that indicate potential needs and expectations for people relative to personal video communications. In particular, users anticipate an easily used, high image quality video system, which enables multitasking communications during the course of real-world activities and provides appropriate privacy controls. To address these needs, we propose a potential approach premised on automated capture of user activity. We then describe a method that adapts cinematography principles, with a dual-camera videography system, to automatically control image capture relative to user activity, using semantic or activity-based cues to determine user position and motion. In particular, we discuss an approach to automatically manage shot framing, shot selection, and shot transitions, with respect to one or more local users engaged in real-time, unscripted events, while transmitting the resulting video to a remote viewer. The goal is to tightly frame subjects (to provide more detail), while minimizing subject loss and repeated abrupt shot framing changes in the images as perceived by a remote viewer. We also discuss some aspects of the system and related technologies that we have experimented with thus far. In summary, the method enables users to participate in interactive video-mediated communications while engaged in other activities.

In-camera automation of photographic composition rules.

PubMed

Banerjee, Serene; Evans, Brian L

2007-07-01

At the time of image acquisition, professional photographers apply many rules of thumb to improve the composition of their photographs. This paper develops a joint optical-digital processing framework for automating composition rules during image acquisition for photographs with one main subject. Within the framework, we automate three photographic composition rules: repositioning the main subject, making the main subject more prominent, and making objects that merge with the main subject less prominent. The idea is to provide to the user alternate pictures obtained by applying photographic composition rules in addition to the original picture taken by the user. The proposed algorithms do not depend on prior knowledge of the indoor/outdoor setting or scene content. The proposed algorithms are also designed to be amenable to software implementation on fixed-point programmable digital signal processors available in digital still cameras.

A System for the Measurement of the Subjective Visual Vertical using a Virtual Reality Device.

PubMed

Negrillo-Cárdenas, José; Rueda-Ruiz, Antonio J; Ogayar-Anguita, Carlos J; Lomas-Vega, Rafael; Segura-Sánchez, Rafael J

2018-05-31

The Subjective Visual Vertical (SVV) is a common test for evaluating the perception of verticality. Altered verticality has been connected with disorders in the otolithic, visual or proprioceptive systems, caused by stroke, Parkinson's disease or multiple sclerosis, among others. Currently, this test is carried out using a variety of specific, mostly homemade apparatuses that include moving planes, buckets, hemispheric domes or a line projected in a screen. Our aim is to develop a flexible, inexpensive, user-friendly and easily extensible system based on virtual reality for the measurement of the SVV and several related visual diagnostic tests, and validate it through an experimental evaluation. Two different hardware configurations were tested with 50 healthy volunteers in a controlled environment; 28 of them were males and 22 females, with ages ranging from 18 to 49 years, being 23 the average age. The Intraclass Correlation Coefficient (ICC) was computed in each device. In addition, a usability survey was conducted. ICC = 0.85 in the first configuration (CI = 0.75-0.92), ICC = 0.76 in the second configuration (CI = 0.61-0.87), both with 95% of confidence, which means a substantial reliability. Moreover, 92.2% of subjects rated the usability of the system as "very good". Our evaluation showed that the proposed system is suitable for the measurement of SVV in healthy subjects. The next step is to perform a more elaborated experimentation on patients and compare the results with the measurements obtained from traditional methods.

A Markov Chain Model for Changes in Users' Assessment of Search Results.

PubMed

Zhitomirsky-Geffet, Maayan; Bar-Ilan, Judit; Levene, Mark

2016-01-01

Previous research shows that users tend to change their assessment of search results over time. This is a first study that investigates the factors and reasons for these changes, and describes a stochastic model of user behaviour that may explain these changes. In particular, we hypothesise that most of the changes are local, i.e. between results with similar or close relevance to the query, and thus belong to the same"coarse" relevance category. According to the theory of coarse beliefs and categorical thinking, humans tend to divide the range of values under consideration into coarse categories, and are thus able to distinguish only between cross-category values but not within them. To test this hypothesis we conducted five experiments with about 120 subjects divided into 3 groups. Each student in every group was asked to rank and assign relevance scores to the same set of search results over two or three rounds, with a period of three to nine weeks between each round. The subjects of the last three-round experiment were then exposed to the differences in their judgements and were asked to explain them. We make use of a Markov chain model to measure change in users' judgments between the different rounds. The Markov chain demonstrates that the changes converge, and that a majority of the changes are local to a neighbouring relevance category. We found that most of the subjects were satisfied with their changes, and did not perceive them as mistakes but rather as a legitimate phenomenon, since they believe that time has influenced their relevance assessment. Both our quantitative analysis and user comments support the hypothesis of the existence of coarse relevance categories resulting from categorical thinking in the context of user evaluation of search results.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alstone, Peter; Jacobson, Arne; Mills, Evan

Efforts to promote rechargeable electric lighting as a replacement for fuel-based light sources in developing countries are typically predicated on the notion that lighting service levels can be maintained or improved while reducing the costs and environmental impacts of existing practices. However, the extremely low incomes of those who depend on fuel-based lighting create a need to balance the hypothetically possible or desirable levels of light with those that are sufficient and affordable. In a pilot study of four night vendors in Kenya, we document a field technique we developed to simultaneously measure the effectiveness of lighting service provided bymore » a lighting system and conduct a survey of lighting service demand by end-users. We took gridded illuminance measurements across each vendor's working and selling area, with users indicating the sufficiency of light at each point. User light sources included a mix of kerosene-fueled hurricane lanterns, pressure lamps, and LED lanterns.We observed illuminance levels ranging from just above zero to 150 lux. The LED systems markedly improved the lighting service levels over those provided by kerosene-fueled hurricane lanterns. Users reported that the minimum acceptable threshold was about 2 lux. The results also indicated that the LED lamps in use by the subjects did not always provide sufficient illumination over the desired retail areas. Our sample size is much too small, however, to reach any conclusions about requirements in the broader population. Given the small number of subjects and very specific type of user, our results should be regarded as indicative rather than conclusive. We recommend replicating the method at larger scales and across a variety of user types and contexts. Policymakers should revisit the subject of recommended illuminance levels regularly as LED technology advances and the price/service balance point evolves.« less

Dopaminergic function in cannabis users and its relationship to cannabis-induced psychotic symptoms.

PubMed

Bloomfield, Michael A P; Morgan, Celia J A; Egerton, Alice; Kapur, Shitij; Curran, H Valerie; Howes, Oliver D

2014-03-15

Cannabis is the most widely used illicit drug globally, and users are at increased risk of mental illnesses including psychotic disorders such as schizophrenia. Substance dependence and schizophrenia are both associated with dopaminergic dysfunction. It has been proposed, although never directly tested, that the link between cannabis use and schizophrenia is mediated by altered dopaminergic function. We compared dopamine synthesis capacity in 19 regular cannabis users who experienced psychotic-like symptoms when they consumed cannabis with 19 nonuser sex- and age-matched control subjects. Dopamine synthesis capacity (indexed as the influx rate constant [Formula: see text] ) was measured with positron emission tomography and 3,4-dihydroxy-6-[(18)F]-fluoro-l-phenylalanine ([(18)F]-DOPA). Cannabis users had reduced dopamine synthesis capacity in the striatum (effect size: .85; t36 = 2.54, p = .016) and its associative (effect size: .85; t36 = 2.54, p = .015) and limbic subdivisions (effect size: .74; t36 = 2.23, p = .032) compared with control subjects. The group difference in dopamine synthesis capacity in cannabis users compared with control subjects was driven by those users meeting cannabis abuse or dependence criteria. Dopamine synthesis capacity was negatively associated with higher levels of cannabis use (r = -.77, p < .001) and positively associated with age of onset of cannabis use (r = .51, p = .027) but was not associated with cannabis-induced psychotic-like symptoms (r = .32, p = .19). These findings indicate that chronic cannabis use is associated with reduced dopamine synthesis capacity and question the hypothesis that cannabis increases the risk of psychotic disorders by inducing the same dopaminergic alterations seen in schizophrenia. Copyright © 2014 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

Comparison of Puff Topography, Toxicant Exposure, and Subjective Effects in Low- and High-Frequency Waterpipe Users: A Double-Blind, Placebo-Control Study

PubMed Central

Cobb, Caroline O.; Blank, Melissa D.; Morlett, Alejandra; Shihadeh, Alan; Jaroudi, Ezzat; Karaoghlanian, Nareg; Kilgalen, Barbara; Austin, Janet; Weaver, Michael F.

2015-01-01

Introduction: Clinical laboratory work among intermittent and daily waterpipe tobacco smokers has revealed significant risks for tobacco dependence and disease associated with waterpipe tobacco smoking (WTS). No studies have compared these groups directly. This study examined whether WTS frequency was associated with differential puff topography, toxicant exposure, and subjective response using a placebo-control design. Methods: Eighty participants reporting WTS of 2–5 episodes (LOW; n = 63) or ≥20 episodes (HIGH; n = 17) per month for ≥6 months completed 2 double-blind, counterbalanced 2-hr sessions that were preceded by ≥12hr of tobacco abstinence. Sessions differed by product smoked ad libitum for 45+ min: preferred brand/flavor of waterpipe tobacco (active) or a flavor-matched tobacco-free waterpipe product (placebo). Outcomes included puff topography, plasma nicotine, carboxyhemoglobin (COHb), and subjective response. Results: HIGH users had more puffs, shorter inter-puff-intervals, and a higher total puff volume for placebo relative to active, as well as relative to LOW users during placebo. Plasma nicotine concentrations increased when smoking active (but not placebo) with no significant differences between groups at 25min post-product administration. COHb increased significantly during all conditions; the largest increase was for HIGH users when smoking placebo. There was some evidence of higher baseline scores for nicotine/tobacco nicotine abstinence symptomology. Conclusions: Higher frequency waterpipe users may be more sensitive to the effects of waterpipe smoke nicotine content. Among HIGH users, higher baseline nicotine/tobacco abstinence symptoms may indicate greater nicotine dependence. These data support continued surveillance of WTS and development of dependence measures specific to this product. PMID:25257982

Communal nesting exerts epigenetic influences on affective and social behaviors in rats selectively bred for an infantile trait.

PubMed

Martinez, Ashley Rae; Brunelli, Susan A; Zimmerberg, Betty

2015-02-01

Communal nesting (CN) is a mouse model of early social enrichment during pregnancy and lactation. In this study, a rat model of CN was developed to determine if CN exerts an epigenetic effect in rats selectively bred for an infantile affective trait (high and low rates of ultrasonic distress calls). High and Low offspring from CN groups were compared to standard reared (SN) offspring on five measures of social and affective behavior at three critical ages. A differential effect of the CN paradigm on High and Low lines was seen in measures of anxiety and arousal, but not in measures of depression or social behavior. Neonatal CN subjects emitted fewer distress calls than SN subjects when separated from their dams, and the High line subjects were more affected by the CN procedure. As juveniles, CN subjects showed increased social behaviors in tests of juvenile parenting and play compared to SN subjects. In adulthood, CN differentially increased the activity of Low line subjects. All CN subjects displayed less anxiety behavior in an open field compared to SN subjects; High line subjects were more anxious than Lows. CN reduced immobility and increased attempts to escape on the Porsolt forced swim task relative to SN subjects. These results extend the usefulness of this early enrichment paradigm from mice to rats, and found some rodent species differences in outcomes dependent on the behavioral test. They also emphasize the importance of social contact during pregnancy and lactation on offspring's optimal development across behaviors and ages. Copyright © 2014 Elsevier Inc. All rights reserved.

Medicinal Δ(9) -tetrahydrocannabinol (dronabinol) impairs on-the-road driving performance of occasional and heavy cannabis users but is not detected in Standard Field Sobriety Tests.

PubMed

Bosker, Wendy M; Kuypers, Kim P C; Theunissen, Eef L; Surinx, Anke; Blankespoor, Roos J; Skopp, Gisela; Jeffery, Wayne K; Walls, H Chip; van Leeuwen, Cees J; Ramaekers, Johannes G

2012-10-01

The acute and chronic effects of dronabinol [medicinal Δ(9) -tetrahydrocannabinol (THC)] on actual driving performance and the Standard Field Sobriety Test (SFST) were assessed. It was hypothesized that occasional users would be impaired on these tests and that heavy users would show less impairment due to tolerance. Double-blind, placebo-controlled, randomized, three-way cross-over study. Twelve occasional and 12 heavy cannabis users (14 males/10 females) received single doses of placebo, 10 and 20 mg dronabinol. Standard deviation of lateral position (SDLP; i.e. weaving) is the primary measure of road-tracking control. Time to speed adaptation (TSA) is the primary reaction-time measure in the car-following test. Percentage of impaired individuals on the SFST and subjective high on a visual analogue scale were secondary measures. Superiority tests showed that SDLP (P = 0.008) and TSA (P = 0.011) increased after dronabinol in occasional users. Equivalence tests demonstrated that dronabinol-induced increments in SDLP were bigger than impairment associated with BAC of 0.5 mg/ml in occasional and heavy users, although the magnitude of driving impairment was generally less in heavy users. The SFST did not discriminate between conditions. Levels of subjective high were comparable in occasional and heavy users. Dronabinol (medicinal tetrahydrocannabinol) impairs driving performance in occasional and heavy users in a dose-dependent way, but to a lesser degree in heavy users due possibly to tolerance. The Standard Field Sobriety Test is not sensitive to clinically relevant driving impairment caused by oral tetrahydrocannabinol. © 2012 The Authors. Addiction © 2012 Society for the Study of Addiction.

The role of the salience network in processing lexical and nonlexical stimuli in cochlear implant users: an ALE meta-analysis of PET studies.

PubMed

Song, Jae-Jin; Vanneste, Sven; Lazard, Diane S; Van de Heyning, Paul; Park, Joo Hyun; Oh, Seung Ha; De Ridder, Dirk

2015-05-01

Previous positron emission tomography (PET) studies have shown that various cortical areas are activated to process speech signal in cochlear implant (CI) users. Nonetheless, differences in task dimension among studies and low statistical power preclude from understanding sound processing mechanism in CI users. Hence, we performed activation likelihood estimation meta-analysis of PET studies in CI users and normal hearing (NH) controls to compare the two groups. Eight studies (58 CI subjects/92 peak coordinates; 45 NH subjects/40 peak coordinates) were included and analyzed, retrieving areas significantly activated by lexical and nonlexical stimuli. For lexical and nonlexical stimuli, both groups showed activations in the components of the dual-stream model such as bilateral superior temporal gyrus/sulcus, middle temporal gyrus, left posterior inferior frontal gyrus, and left insula. However, CI users displayed additional unique activation patterns by lexical and nonlexical stimuli. That is, for the lexical stimuli, significant activations were observed in areas comprising salience network (SN), also known as the intrinsic alertness network, such as the left dorsal anterior cingulate cortex (dACC), left insula, and right supplementary motor area in the CI user group. Also, for the nonlexical stimuli, CI users activated areas comprising SN such as the right insula and left dACC. Previous episodic observations on lexical stimuli processing using the dual auditory stream in CI users were reconfirmed in this study. However, this study also suggests that dual-stream auditory processing in CI users may need supports from the SN. In other words, CI users need to pay extra attention to cope with degraded auditory signal provided by the implant. © 2015 Wiley Periodicals, Inc.

Discovery and Analysis of Intersecting Datasets: JMARS as a Comparative Science Platform

NASA Astrophysics Data System (ADS)

Carter, S.; Christensen, P. R.; Dickenshied, S.; Anwar, S.; Noss, D.

2014-12-01

A great deal can be discovered from comparing and studying a chosen region or area on a planetary body. In this age, science has an enormous amount of instruments and data to study from; often the first obstacle can be finding the right information. Developed at Arizona State University, Java Mission-planning and Analysis for Remote Sensing (JMARS), enables users to easily find and study related datasets. JMARS supports a long list of planetary bodies in our solar system, including Earth, the Moon, Mars, and other planets, satellites, and asteroids. Within JMARS a user can start with a particular area and search for all datasets that have images/information intersecting that region of interest. Once a user has found data they are interested in comparing, they can view the image at once and see the numeric information at that location. This information can be analyzed in a few powerful ways. If the dataset of interest varies with time but the location stays constant, then the user may want to compare specific locations through time. This can be done the Investigate Tool in JMARS. Users can create a Data Spike and the information at that point will be plotted through time. If the region does not have a temporal dataset, then a different method would be suitable and involves a profile line. Also using the Investigate Tool, a user can create a Data Profile (a line which can contain as many vertices as necessary) and all numeric data underneath the line will be plotted on one graph for easy comparison. This can be used to compare differences between similar datasets - perhaps the same measurement but from different instruments - or to find correlations from one dataset to another. A third form of analysis is planned for future development. This method involves entire areas (polygons). Sampling of the different data sources beneath an area can reveal statistics like maximum, minimum, and average values, and standard deviation. These values can be compared to other data sources under the given area. JMARS has the ability to geographically locate and display a vast array of remote sensing data for a user. In addition to its powerful searching ability, it also enables users to compare datasets using the Data Spike and Data Profile techniques. Plots and tables from this data can be exported and used in presentations, papers, or external software for further study.

Goal selection versus process control while learning to use a brain-computer interface

NASA Astrophysics Data System (ADS)

Royer, Audrey S.; Rose, Minn L.; He, Bin

2011-06-01

A brain-computer interface (BCI) can be used to accomplish a task without requiring motor output. Two major control strategies used by BCIs during task completion are process control and goal selection. In process control, the user exerts continuous control and independently executes the given task. In goal selection, the user communicates their goal to the BCI and then receives assistance executing the task. A previous study has shown that goal selection is more accurate and faster in use. An unanswered question is, which control strategy is easier to learn? This study directly compares goal selection and process control while learning to use a sensorimotor rhythm-based BCI. Twenty young healthy human subjects were randomly assigned either to a goal selection or a process control-based paradigm for eight sessions. At the end of the study, the best user from each paradigm completed two additional sessions using all paradigms randomly mixed. The results of this study were that goal selection required a shorter training period for increased speed, accuracy, and information transfer over process control. These results held for the best subjects as well as in the general subject population. The demonstrated characteristics of goal selection make it a promising option to increase the utility of BCIs intended for both disabled and able-bodied users.

Effects of transient blur and VDT screen luminance changes on eyeblink rate.

PubMed

Cardona, Genís; Gómez, Marcelo; Quevedo, Lluïsa; Gispets, Joan

2014-10-01

A study was designed to evaluate the efficacy of three different strategies aiming at increasing spontaneous eyeblink rate (SEBR) during computer use. A total of 12 subjects (5 female) with a mean age of 28.7 years were instructed to read a text presented on a computer display terminal during 15min. Four reading sessions (reference and three "blinking events" [BE]) were programmed in which SEBR was digitally recorded. "Blinking events" were based on either a slight distortion of the text characters or on the presentation of a white screen instead of the text, with or without accompanying blinking instructions. All BE had a duration of 20ms and occurred every 15s. Participants graded the intrusiveness of each BE configuration, and the number of lines participants read in each session was recorded. Data from 11 subjects was analysed. A statistically significant difference in SEBR was encountered between the experimental configuration consisting on a white screen plus blinking instructions (7.8 blinks/min) and both reference (5.2 blinks/min; p=0.049) and white screen without blinking instructions (4.8 blinks/min; p=0.038). All three BE had superior levels of intrusiveness than reference conditions, although the performance of participants (line count) was not compromised. The joint contribution of white screen and blinking instructions has been shown to result in a short term improvement in blinking rate in the present sample of non-dry eye computer users. Further work is necessary to improve the acceptance of any BE aiming at influencing SEBR. Copyright © 2014 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.

Elliptical broken line method for calculating capillary density in nailfold capillaroscopy: Proposal and evaluation.

PubMed

Karbalaie, Abdolamir; Abtahi, Farhad; Fatemi, Alimohammad; Etehadtavakol, Mahnaz; Emrani, Zahra; Erlandsson, Björn-Erik

2017-09-01

Nailfold capillaroscopy is a practical method for identifying and obtaining morphological changes in capillaries which might reveal relevant information about diseases and health. Capillaroscopy is harmless, and seems simple and repeatable. However, there is lack of established guidelines and instructions for acquisition as well as the interpretation of the obtained images; which might lead to various ambiguities. In addition, assessment and interpretation of the acquired images are very subjective. In an attempt to overcome some of these problems, in this study a new modified technique for assessment of nailfold capillary density is introduced. The new method is named elliptic broken line (EBL) which is an extension of the two previously known methods by defining clear criteria for finding the apex of capillaries in different scenarios by using a fitted elliptic. A graphical user interface (GUI) is developed for pre-processing, manual assessment of capillary apexes and automatic correction of selected apexes based on 90° rule. Intra- and inter-observer reliability of EBL and corrected EBL is evaluated in this study. Four independent observers familiar with capillaroscopy performed the assessment for 200 nailfold videocapillaroscopy images, form healthy subject and systemic lupus erythematosus patients, in two different sessions. The results show elevation from moderate (ICC=0.691) and good (ICC=0.753) agreements to good (ICC=0.750) and good (ICC=0.801) for intra- and inter-observer reliability after automatic correction of EBL. This clearly shows the potential of this method to improve the reliability and repeatability of assessment which motivates us for further development of automatic tool for EBL method. Copyright © 2017 Elsevier Inc. All rights reserved.

Evaluation of Usability and Acceptance of a New Autoinjector Intended for Methotrexate Subcutaneous Self-Administration in the Management of Rheumatoid Arthritis.

PubMed

Hudry, Christophe; Lebrun, Agnès; Moura, Bertrand; Zinovieva, Elena; Backers, Onne; Herman-Demars, Hélène

2017-06-01

Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease, for which the introduction of injectable treatments has had a major impact on quality of life directly related to the disease. The purpose of this descriptive study was to evaluate the usability of a new autoinjector, intended for methotrexate self-administration, based on the device's design and instructions for use (IFU). This multicenter trial included three user groups: a group of patients with established RA subdivided into two groups according to their hand disability, and a group of caregivers or nurses. Each subject performed three simulated injections with a water-filled device on a foam pad. The first injection was made just after reading the IFU without further instructions (first phase). The second phase consisted of two injections made after explanations provided upon request of the subject in an optimum environment and in a "worst-case" home environment. The usability of the autoinjector was assessed by a questionnaire (success: ≥75% of positive responses) and by a score card reflecting injection performances (success: execution of ≥75% of handling steps). Forty-two subjects were enrolled in the study. During the first phase, the great majority of subjects succeeded in the usability questionnaire (90.5%) and in the injection performance (95.2%) with no major differences between the user groups. In the Second phase, all subjects from all three user groups succeeded in the usability questionnaire and had a positive rate of device handling, regardless of the environment and of the user group. No safety concerns were raised during the study. This study found a very high level of usability and subject acceptance of the autoinjector, intended for methotrexate self-administration, regardless of the hand disability and environmental conditions. Nordic Group. EudraCT reference number: 2014-A0141245.

WCPP-THE WOLF PLOTTING AND CONTOURING PACKAGE

NASA Technical Reports Server (NTRS)

Masaki, G. T.

1994-01-01

The WOLF Contouring and Plotting Package provides the user with a complete general purpose plotting and contouring capability. This package is a complete system for producing line printer, SC4020, Gerber, Calcomp, and SD4060 plots. The package has been designed to be highly flexible and easy to use. Any plot from a quick simple plot (which requires only one call to the package) to highly sophisticated plots (including motion picture plots) can be easily generated with only a basic knowledge of FORTRAN and the plot commands. Anyone designing a software system that requires plotted output will find that this package offers many advantages over the standard hardware support packages available. The WCPP package is divided into a plot segment and a contour segment. The plot segment can produce output for any combination of line printer, SC4020, Gerber, Calcomp, and SD4060 plots. The line printer plots allow the user to have plots available immediately after a job is run at a low cost. Although the resolution of line printer plots is low, the quick results allows the user to judge if a high resolution plot of a particular run is desirable. The SC4020 and SD4060 provide high speed high resolution cathode ray plots with film and hard copy output available. The Gerber and Calcomp plotters provide very high quality (of publishable quality) plots of good resolution. Being bed or drum type plotters, the Gerber and Calcomp plotters are usually slow and not suited for large volume plotting. All output for any or all of the plotters can be produced simultaneously. The types of plots supported are: linear, semi-log, log-log, polar, tabular data using the FORTRAN WRITE statement, 3-D perspective linear, and affine transformations. The labeling facility provides for horizontal labels, vertical labels, diagonal labels, vector characters of a requested size (special character fonts are easily implemented), and rotated letters. The gridding routines label the grid lines according to user specification. Special line features include multiple lines, dashed lines, and tic marks. The contour segment of this package is a collection of subroutines which can be used to produce contour plots and perform related functions. The package can contour any data which can be placed on a grid or data which is regularly spaced, including any general affine or polar grid data. The package includes routines which will grid random data. Contour levels can be specified at any values desired. Input data can be smoothed with undefined points being acceptable where data is unreliable or unknown. Plots which are extremely large or detailed can be automatically output in parts to improve resolution or overcome plotter size limitations. The contouring segment uses the plot segment for actual plotting, thus all the features described for the plotting segment are available to the user of the contouring segment. Included with this package are two data bases for producing world map plots in Mercator projection. One data base provides just continent outlines and another provides continent outlines and national borders in great detail. This package is written in FORTRAN IV and IBM OS ASSEMBLER and has been implemented on an IBM 360 with a central memory requirement of approximately 140K of 8 bit bytes. The ASSEMBLER routines are basic plotter interface routines. The WCPP package was developed in 1972.

Is talking to an automated teller machine natural and fun?

PubMed

Chan, F Y; Khalid, H M

Usability and affective issues of using automatic speech recognition technology to interact with an automated teller machine (ATM) are investigated in two experiments. The first uncovered dialogue patterns of ATM users for the purpose of designing the user interface for a simulated speech ATM system. Applying the Wizard-of-Oz methodology, multiple mapping and word spotting techniques, the speech driven ATM accommodates bilingual users of Bahasa Melayu and English. The second experiment evaluates the usability of a hybrid speech ATM, comparing it with a simulated manual ATM. The aim is to investigate how natural and fun can talking to a speech ATM be for these first-time users. Subjects performed the withdrawal and balance enquiry tasks. The ANOVA was performed on the usability and affective data. The results showed significant differences between systems in the ability to complete the tasks as well as in transaction errors. Performance was measured on the time taken by subjects to complete the task and the number of speech recognition errors that occurred. On the basis of user emotions, it can be said that the hybrid speech system enabled pleasurable interaction. Despite the limitations of speech recognition technology, users are set to talk to the ATM when it becomes available for public use.

Single-Trial Classification of Multi-User P300-Based Brain-Computer Interface Using Riemannian Geometry.

PubMed

Korczowski, L; Congedo, M; Jutten, C

2015-08-01

The classification of electroencephalographic (EEG) data recorded from multiple users simultaneously is an important challenge in the field of Brain-Computer Interface (BCI). In this paper we compare different approaches for classification of single-trials Event-Related Potential (ERP) on two subjects playing a collaborative BCI game. The minimum distance to mean (MDM) classifier in a Riemannian framework is extended to use the diversity of the inter-subjects spatio-temporal statistics (MDM-hyper) or to merge multiple classifiers (MDM-multi). We show that both these classifiers outperform significantly the mean performance of the two users and analogous classifiers based on the step-wise linear discriminant analysis. More importantly, the MDM-multi outperforms the performance of the best player within the pair.

The Nearness of You: Students & Teachers Writing On-Line.

ERIC Educational Resources Information Center

Edgar, Christopher, Ed.; Wood, Susan Nelson, Ed.

This book is a guide to using new computer technologies in innovative ways to teach writing, particularly imaginative writing. The book shows how on-line technology can be a positive tool in the classroom, if the focus is on the users of the technology and the technology is integrated into the curriculum. The book is divided into five sections and…

Intelligent editor/printer enhancements

NASA Technical Reports Server (NTRS)

Woodfill, M. C.; Pheanis, D. C.

1983-01-01

Microprocessor support hardware, software, and cross assemblers relating to the Motorola 6800 and 6809 process systems were developed. Pinter controller and intelligent CRT development are discussed. The user's manual, design specifications for the MC6809 version of the intelligent printer controller card, and a 132-character by 64-line intelligent CRT display system using a Motorola 6809 MPU, and a one-line assembler and disassembler are provided.

Development of the Defense Documentation Center Remote On-Line Retrieval System - Past, Present and Future.

ERIC Educational Resources Information Center

Bennertz, Richard K.

The document highlights in nontechnical language the development of the Defense Documentation Center (DDC) Remote On-Line Retrieval System from its inception in 1967 to what is planned. It describes in detail the current operating system, equipment configuration and associated costs, user training and system evaluation and may be of value to other…

NASIS data base management system - IBM 360/370 OS MVT implementation. 7: Data base administrator user's guide

NASA Technical Reports Server (NTRS)

1973-01-01

The Data Base Administrator User's Guide for the NASA Aerospace Safety information system is presented. The subjects discussed are: (1) multi-terminal tasking, (2) data base executive, (3) utilities, (4) maintenance, and (5) update mode functions.

Kinematics effectively delineate accomplished users of endovascular robotics with a physical training model.

PubMed

Duran, Cassidy; Estrada, Sean; O'Malley, Marcia; Lumsden, Alan B; Bismuth, Jean

2015-02-01

Endovascular robotics systems, now approved for clinical use in the United States and Europe, are seeing rapid growth in interest. Determining who has sufficient expertise for safe and effective clinical use remains elusive. Our aim was to analyze performance on a robotic platform to determine what defines an expert user. During three sessions, 21 subjects with a range of endovascular expertise and endovascular robotic experience (novices <2 hours to moderate-extensive experience with >20 hours) performed four tasks on a training model. All participants completed a 2-hour training session on the robot by a certified instructor. Completion times, global rating scores, and motion metrics were collected to assess performance. Electromagnetic tracking was used to capture and to analyze catheter tip motion. Motion analysis was based on derivations of speed and position including spectral arc length and total number of submovements (inversely proportional to proficiency of motion) and duration of submovements (directly proportional to proficiency). Ninety-eight percent of competent subjects successfully completed the tasks within the given time, whereas 91% of noncompetent subjects were successful. There was no significant difference in completion times between competent and noncompetent users except for the posterior branch (151 s:105 s; P = .01). The competent users had more efficient motion as evidenced by statistically significant differences in the metrics of motion analysis. Users with >20 hours of experience performed significantly better than those newer to the system, independent of prior endovascular experience. This study demonstrates that motion-based metrics can differentiate novice from trained users of flexible robotics systems for basic endovascular tasks. Efficiency of catheter movement, consistency of performance, and learning curves may help identify users who are sufficiently trained for safe clinical use of the system. This work will help identify the learning curve and specific movements that translate to expert robotic navigation. Copyright © 2015 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.