Sample records for summary based approval

  1. 77 FR 6529 - Approval and Promulgation of Implementation Plans; Alabama, Georgia, and Tennessee: Chattanooga...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-08

    ...; Particulate Matter 2002 Base Year Emissions Inventory AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is proposing to approve the fine particulate matter (PM 2.5 ) 2002 base year...

  2. 77 FR 45532 - Approval and Promulgation of Implementation Plans; Michigan; Detroit-Ann Arbor Nonattainment Area...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-01

    ... 2005 Base Year Emissions Inventory AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is proposing to approve the fine particulate matter (PM 2.5 ) 2005 base year emissions...) plan, contingency measures, a 2005 base year emissions inventory and other planning SIP revisions...

  3. 77 FR 66547 - Approval and Promulgation of Implementation Plans; Michigan; Detroit-Ann Arbor Nonattainment Area...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-06

    ... 2005 Base Year Emissions Inventory AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY: EPA is approving the fine particulate matter (PM 2.5 ) 2005 base year emissions inventory, a... 2005 base year emissions inventory for the Detroit-Ann Arbor area. EPA did not receive any comments...

  4. 77 FR 24440 - Approval and Promulgation of Implementation Plans; Georgia; Atlanta; Ozone 2002 Base Year...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-24

    ... Promulgation of Implementation Plans; Georgia; Atlanta; Ozone 2002 Base Year Emissions Inventory AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is proposing to approve the ozone... (hereafter referred to as ``the Atlanta Area'' or ``Area''), ozone attainment demonstration that was...

  5. 77 FR 75933 - Approval and Promulgation of Air Quality Implementation Plans; West Virginia; The 2002 Base Year...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-26

    ... Promulgation of Air Quality Implementation Plans; West Virginia; The 2002 Base Year Emissions Inventory for the...: Proposed rule. SUMMARY: EPA is proposing to approve the 2002 base year emissions inventory portion of the... inventory is part of a SIP revision that was submitted to meet West Virginia's nonattainment requirements...

  6. How IPCC Science-Policy Interactions Shape Its Policymaker Summaries

    NASA Astrophysics Data System (ADS)

    Mach, K. J.; Freeman, P. T.; Mastrandrea, M.; Field, C. B.

    2016-12-01

    Government approval is a defining feature of the Intergovernmental Panel on Climate Change (IPCC) assessment process. In plenary sessions with scientist authors, IPCC member governments discuss and agree each sentence of every report's summary for policymakers (SPM). This consensus-based approval builds joint ownership of scientific knowledge by both scientists and governments. The approval process and its resulting SPM revisions have received extensive attention in published anecdotes and perspectives, but without comprehensive evaluation to date. We present the results of an in-depth analysis of IPCC SPM revisions, providing an evidence basis for understanding a complex science-policy interaction. Revisions resulting from governmental review and approval expand SPMs. SPM text lengthens by 17 to 53% in recent assessment summaries. Political sensitivities and associated failures of consensus have led to prominent exceptions resulting in SPM contractions. Contrasting recent assertions, we find IPCC SPMs to be as readable as other professionally edited assessment summaries, for multiple measures of reading ease. Across metrics, some SPMs, but not all, become more readable through the revision process. We additionally examine each revision in an SPM for which we have deep familiarity. Most of the SPM's revisions occur prior to the in-person government-approval session, and they emphasize different purposes compared to revisions made during the approval session. Revisions prior to the in-person session largely pertain to clarity, scientific rigor, and explanation, whereas the subsequent in-person government-approval revisions place more emphasis on policy relevance, comprehensiveness of examples, and nuances of expert judgment. The value added in the IPCC government-approval process emerges through multiple stages of revision and approval, as scientists and governments together navigate a complex science-policy interaction.

  7. 75 FR 57912 - Boulder Canyon Project-Rate Order No. WAPA-150

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-23

    ...-setting Formula and Approval of FY 2011 Base Charge and Rates. SUMMARY: The Deputy Secretary of Energy... existing Boulder Canyon Project (BCP) rate-setting formula and approving the base charge and rates for FY... financial and load data. The existing rate-setting formula is being extended under Rate Order No. WAPA-150...

  8. 77 FR 58058 - Approval and Promulgation of Implementation Plans; Texas; Beaumont/Port Arthur Ozone Maintenance...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-19

    .... SUMMARY: EPA is proposing to approve Texas' request to revise its Beaumont/Port Arthur (BPA) 1997 8-hour... (MOVES) 2010a emissions model. The BPA 1997 8-hour ozone maintenance area consists of Hardin, Jefferson... proposing? EPA is proposing to approve new MOVES2010a-based budgets for the Beaumont/Port Arthur (BPA) 1997...

  9. 75 FR 31477 - Neighborworks America; Regular Board of Directors Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-03

    ... Corporate Secretary (202) 220-2376; [email protected] . Agenda I. Call To Order. II. Approval of the Minutes. III. Approval of the Minutes. IV. Summary Report of the Audit Committee. V. Summary Report of the Finance... the NHSA Special Board of Directors Meeting. VIII. Summary Report of the Corporate Administration...

  10. 75 FR 6813 - Approval of Air Quality Implementation Plans; New Mexico; Albuquerque/Bernalillo County

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-11

    ...). ACTION: Direct final rule. SUMMARY: The EPA is approving revisions to the State Implementation Plan (SIP.... Background III. Summary of Changes to the New Mexico SIP IV. Final Action V. Statutory and Executive Order Reviews I. What Action Is EPA Taking? Today we are approving revisions to the New Mexico SIP, submitted by...

  11. Assessment of the Impact of Scheduled Postmarketing Safety Summary Analyses on Regulatory Actions

    PubMed Central

    Sekine, S; Pinnow, EE; Wu, E; Kurtzig, R; Hall, M; Dal Pan, GJ

    2016-01-01

    In addition to standard postmarketing drug safety monitoring, Section 915 of the Food and Drug Administration Amendments Act of 2007 (FDAAA) requires the US Food and Drug Administration (FDA) to conduct a summary analysis of adverse event reports to identify risks of a drug or biologic product 18 months after product approval, or after 10,000 patients have used the product, whichever is later. We assessed the extent to which these analyses identified new safety signals and resultant safety-related label changes. Among 458 newly approved products, 300 were the subjects of a scheduled analysis; a new safety signal that resulted in a safety-related label change was found for 11 of these products. Less than 2% of 713 safety-related label changes were based on the scheduled analyses. Our study suggests that the safety summary analyses provide only marginal value over other pharmacovigilance activities. PMID:26853718

  12. U.S. Food and Drug Administration approval summary: Eltrombopag for the treatment of pediatric patients with chronic immune (idiopathic) thrombocytopenia.

    PubMed

    Ehrlich, Lori A; Kwitkowski, Virginia E; Reaman, Gregory; Ko, Chia-Wen; Nie, Lei; Pazdur, Richard; Farrell, Ann T

    2017-12-01

    The U.S. Food and Drug Administration (FDA) approved eltrombopag for pediatric patients with chronic immune (idiopathic) thrombocytopenia (ITP) ages ≥6 on June 11, 2015, and ages ≥1 on August 24, 2015. Approval was based on the FDA review of two randomized trials that included 159 pediatric patients with chronic ITP who had an insufficient response to corticosteroids, immunoglobulins, or splenectomy. This manuscript describes the basis for approval of these applications. The FDA concluded that eltrombopag has shown efficacy and a favorable benefit to risk profile for pediatric patients with chronic ITP. © 2017 Wiley Periodicals, Inc.

  13. 77 FR 50494 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-21

    ... data and summary statistics, addressing the program's current design and coverage; a summary of testing... identified in the OMB Inventory of Approved ICR Burdens. This decrease is due to (1) a mathematical error...

  14. ULSGEN (Uplink Summary Generator)

    NASA Technical Reports Server (NTRS)

    Wang, Y.-F.; Schrock, M.; Reeve, T.; Nguyen, K.; Smith, B.

    2014-01-01

    Uplink is an important part of spacecraft operations. Ensuring the accuracy of uplink content is essential to mission success. Before commands are radiated to the spacecraft, the command and sequence must be reviewed and verified by various teams. In most cases, this process requires collecting the command data, reviewing the data during a command conference meeting, and providing physical signatures by designated members of various teams to signify approval of the data. If commands or sequences are disapproved for some reason, the whole process must be restarted. Recording data and decision history is important for traceability reasons. Given that many steps and people are involved in this process, an easily accessible software tool for managing the process is vital to reducing human error which could result in uplinking incorrect data to the spacecraft. An uplink summary generator called ULSGEN was developed to assist this uplink content approval process. ULSGEN generates a web-based summary of uplink file content and provides an online review process. Spacecraft operations personnel view this summary as a final check before actual radiation of the uplink data. .

  15. Ground-Based Calibration Support for Two Approved HST Programs

    NASA Technical Reports Server (NTRS)

    Stauffer, John R.

    1998-01-01

    This final report is a summary of the study on ground-based calibration support for two approved HST programs. A large set of new rotational periods for low mass stars in the Pleiades open cluster have been published and used to help interpret chromospheric and coronal activity indicators for low mass stars in the cluster. The Caltech/TJC/NASA Keck telescope in Hawaii has also been used to obtain spectra of brown dwarf candidates in the Pleiades. Those spectra help to derive an accurate and precise new age for that fiducial open cluster.

  16. Tan Son Nhut AB, Saigon, Vietnam. Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F

    DTIC Science & Technology

    1973-10-12

    Distribution Unlimited L’ ’-- -- - 7 - 77 N4®r" I4~ "’ - ’ - Review and Approval Statement This report is approved for public release. There is no objection...report has been reviewed and is approved for publication. •C C O M , C hr e Technical Information Section a USAFETAC/TST FOR THE COMMANDER ! W S . URGA A...TAN SON NHUT AS VIETNAM/SAIGON .... .65-71 STAIION STATION NAME YEARS DAILY SNOW DEPTH IN INCMES /bASED ON LESS THAN FULL MONTHS/ MAPEH JUN J ALL YER

  17. Connected vehicle pilot deployment program phase 1 : human use approval summary – Tampa.

    DOT National Transportation Integrated Search

    2016-07-18

    This document presents the Human Use Approval (HUA) Summary for the THEA Connected Vehicle (CV) Pilot Deployment. The purpose of this report is to document the process used by THEA in the Tampa CV Pilot Deployment as required in Phase 1, Task 8 in pr...

  18. 75 FR 13598 - Regular Board of Directors Meeting; Sunshine Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-22

    ... 20005. STATUS: Open. CONTACT PERSON FOR MORE INFORMATION: Erica Hall, Assistant Corporate Secretary... of the Corporate Administration Committee IV. Approval of the Minutes V. Summary Report of the Audit Committee VI. Approval of the Minutes VII. Summary Report of the Finance, Budget and Program Committee VIII...

  19. 77 FR 21143 - Projects Approved for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-09

    ... SUSQUEHANNA RIVER BASIN COMMISSION Projects Approved for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: This notice lists the projects approved by rule..., receiving approval for the consumptive use of water pursuant to the Commission's approval by rule process...

  20. 78 FR 11947 - Projects Approved for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-20

    ... SUSQUEHANNA RIVER BASIN COMMISSION Projects Approved for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: This notice lists the projects approved by rule..., receiving approval for the consumptive use of water pursuant to the Commission's approval by rule process...

  1. 78 FR 17281 - Projects Approved for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-20

    ... SUSQUEHANNA RIVER BASIN COMMISSION Projects Approved for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: This notice lists the projects approved by rule..., receiving approval for the consumptive use of water pursuant to the Commission's approval by rule process...

  2. 77 FR 66909 - Projects Approved for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-07

    ... SUSQUEHANNA RIVER BASIN COMMISSION Projects Approved for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: This notice lists the projects approved by rule... below, receiving approval for the consumptive use of water pursuant to the Commission's approval by rule...

  3. 78 FR 2315 - Projects Approved for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-10

    ... SUSQUEHANNA RIVER BASIN COMMISSION Projects Approved for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: This notice lists the projects approved by rule..., receiving approval for the consumptive use of water pursuant to the Commission's approval by rule process...

  4. 78 FR 15402 - Projects Approved for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-11

    ... SUSQUEHANNA RIVER BASIN COMMISSION Projects Approved for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: This notice lists the projects approved by rule..., receiving approval for the consumptive use of water pursuant to the Commission's approval by rule process...

  5. 77 FR 25010 - Projects Approved for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-26

    ... SUSQUEHANNA RIVER BASIN COMMISSION Projects Approved for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: This notice lists the projects approved by rule... below, receiving approval for the consumptive use of water pursuant to the Commission's approval by rule...

  6. 77 FR 55892 - Projects Approved for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-11

    ... SUSQUEHANNA RIVER BASIN COMMISSION Projects Approved for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: This notice lists the projects approved by rule..., receiving approval for the consumptive use of water pursuant to the Commission's approval by rule process...

  7. 77 FR 55891 - Projects Approved for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-11

    ... SUSQUEHANNA RIVER BASIN COMMISSION Projects Approved for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: This notice lists the projects approved by rule..., receiving approval for the consumptive use of water pursuant to the Commission's approval by rule process...

  8. 77 FR 59239 - Projects Approved for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-26

    ... SUSQUEHANNA RIVER BASIN COMMISSION Projects Approved for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: This notice lists the projects approved by rule..., receiving approval for the consumptive use of water pursuant to the Commission's approval by rule process...

  9. 77 FR 16317 - Projects Approved for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-20

    ... SUSQUEHANNA RIVER BASIN COMMISSION Projects Approved for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: This notice lists the projects approved by rule..., receiving approval for the consumptive use of water pursuant to the Commission's approval by rule process...

  10. 77 FR 34455 - Projects Approved for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... SUSQUEHANNA RIVER BASIN COMMISSION Projects Approved for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: This notice lists the projects approved by rule..., receiving approval for the consumptive use of water pursuant to the Commission's approval by rule process...

  11. 77 FR 14531 - Proposed Collection; Comment Request; Web-Based Assessment of the NHLBI Clinical Studies Support...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-12

    ... Request; Web-Based Assessment of the NHLBI Clinical Studies Support Center (CSSC) SUMMARY: In compliance... the Office of Management and Budget (OMB) for review and approval. Proposed Collection: Title: Web...); coordinating meeting space and logistics for in-person meetings, Web conferences, and teleconferences; managing...

  12. 75 FR 36099 - Medical Devices; Availability of Safety and Effectiveness Summaries for Premarket Approval...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-24

    ... of the availability of safety and effectiveness summaries of approved PMAs through the Internet and... New Hampshire Ave., Bldg. 66, rm. 1650, Silver Spring, MD 20993, 301-796- 6570. SUPPLEMENTARY... and denials in the Federal Register. Instead, the agency now posts this information on the Internet on...

  13. 75 FR 54154 - Medical Devices; Availability of Safety and Effectiveness Summaries for Premarket Approval...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-03

    ... effectiveness summaries of approved PMAs through the Internet and the agency's Division of Dockets Management... and Radiological Health, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 66, rm. 1650... Federal Register. Instead, the agency now posts this information on the Internet on FDA's home page at...

  14. 75 FR 72829 - Medical Devices; Availability of Safety and Effectiveness Summaries for Premarket Approval...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-26

    ... and effectiveness summaries of approved PMAs through the Internet and the Agency's Division of Dockets..., Center for Devices and Radiological Health, Food and Drug Administration, 10903 New Hampshire Ave., Bldg... Federal Register. Instead, the Agency now posts this information on the Internet on FDA's home page at...

  15. FDA Approvals - Cancer Currents Blog

    Cancer.gov

    Blog posts on cancer drugs and devices approved by the Food and Drug Administration—including summaries of the evidence to support the approvals and what they mean for patients—from NCI Cancer Currents.

  16. 76 FR 53526 - Projects Approved for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-26

    ... SUSQUEHANNA RIVER BASIN COMMISSION Projects Approved for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: This notice lists the projects approved by rule... lists the projects, described below, receiving approval for the consumptive use of water pursuant to the...

  17. 77 FR 4859 - Projects Approved for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-31

    ... SUSQUEHANNA RIVER BASIN COMMISSION Projects Approved for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: This notice lists the projects approved by rule... notice lists the projects, described below, receiving approval for the consumptive use of water pursuant...

  18. 76 FR 66117 - Projects Approved for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-25

    ... SUSQUEHANNA RIVER BASIN COMMISSION Projects Approved for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: This notice lists the projects approved by rule... notice lists the projects, described below, receiving approval for the consumptive use of water pursuant...

  19. 76 FR 42159 - Projects Approved for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-18

    ... SUSQUEHANNA RIVER BASIN COMMISSION Projects Approved for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: This notice lists the projects approved by rule... lists the projects, described below, receiving approval for the consumptive use of water pursuant to the...

  20. 77 FR 31866 - Intent To Request Approval From OMB of One New Public Collection of Information: Baseline...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-30

    ... (BASE) Program for Public Transportation Systems AGENCY: Transportation Security Administration, DHS. ACTION: 60-day Notice. SUMMARY: The Transportation Security Administration (TSA) invites public comment... under contract with a public transportation agency. \\1\\ TSA, ``Transportation Sector-Specific Plan Mass...

  1. 75 FR 24711 - Fiscal Year (FY) 2010 Funding Opportunity

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-05

    ... Assistance Center for Mental Health Promotion and Youth Violence Prevention. SUMMARY: This notice is to... Mental Health Promotion and Youth Violence Prevention. This is not a formal request for applications... Promotion and Youth Violence Prevention based on the receipt of a satisfactory application that is approved...

  2. Gonzalez Regimen (PDQ®)—Patient Version

    Cancer.gov

    The Gonzalez regimen is a complex treatment plan based on the role of enzymes, vitamins, minerals, and other dietary factors. The US Food and Drug Administration has not approved the Gonzalez regimen or any of its components as a cancer treatment. Learn more in this expert-reviewed summary.

  3. 75 FR 983 - Cross-Media Electronic Reporting Rule State Approved Program Revision/Modification Approvals...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-07

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9099-3] Cross-Media Electronic Reporting Rule State Approved...). ACTION: Notice. SUMMARY: This notice announces EPA's approval, under regulations for Cross-Media..., [email protected] . SUPPLEMENTARY INFORMATION: On October 13, 2005, the final Cross-Media Electronic...

  4. 75 FR 71177 - Notice of Projects Approved for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-22

    ... SUSQUEHANNA RIVER BASIN COMMISSION Notice of Projects Approved for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice of approved projects. SUMMARY: This notice... for the consumptive use of water pursuant to the Commission's approval by rule process set forth in 18...

  5. 75 FR 23837 - Notice of Projects Approved for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-04

    ... SUSQUEHANNA RIVER BASIN COMMISSION Notice of Projects Approved for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice of approved projects. SUMMARY: This notice... consumptive use of water pursuant to the Commission's approval by rule process set forth in 18 CFR 806.22(e...

  6. 75 FR 38591 - Notice of Projects Approved for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-02

    ... SUSQUEHANNA RIVER BASIN COMMISSION Notice of Projects Approved for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice of Approved Projects. SUMMARY: This notice... consumptive use of water pursuant to the Commission's approval by rule process set forth in and 18 CFR 806.22...

  7. 78 FR 6096 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-29

    ... Activities; Submission to OMB for Review and Approval; Comment Request; NESHAP for Miscellaneous Organic Chemical Manufacturing (Renewal) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: In... review and approval. This is a request to renew an existing approved collection. The ICR which is...

  8. A multistage crucible of revision and approval shapes IPCC policymaker summaries.

    PubMed

    Mach, Katharine J; Freeman, Patrick T; Mastrandrea, Michael D; Field, Christopher B

    2016-08-01

    Intergovernmental Panel on Climate Change (IPCC) member governments approve each report's summary for policymakers (SPM) by consensus, discussing and agreeing on each sentence in a plenary session with scientist authors. A defining feature of IPCC assessment, the governmental approval process builds joint ownership of current knowledge by scientists and governments. The resulting SPM revisions have been extensively discussed in anecdotes, interviews, and perspectives, but they have not been comprehensively analyzed. We provide an in-depth evaluation of IPCC SPM revisions, establishing an evidential basis for understanding their nature. Revisions associated with governmental review and approval generally expand SPMs, with SPM text growing by 17 to 53% across recent assessment reports. Cases of high political sensitivity and failure to reach consensus are notable exceptions, resulting in SPM contractions. In contrast to recent claims, we find that IPCC SPMs are as readable, for multiple metrics of reading ease, as other professionally edited assessment summaries. Across reading-ease metrics, some SPMs become more readable through governmental review and approval, whereas others do not. In an SPM examined through the entire revision process, most revisions associated with governmental review and approval occurred before the start of the government-approval plenary session. These author revisions emphasize clarity, scientific rigor, and explanation. In contrast, the subsequent plenary revisions place greater emphasis especially on policy relevance, comprehensiveness of examples, and nuances of expert judgment. Overall, the value added by the IPCC process emerges in a multistage crucible of revision and approval, as individuals together navigate complex science-policy terrain.

  9. 29 CFR 1955.22 - Summary decision.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Summary decision. 1955.22 Section 1955.22 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR WITHDRAWAL OF APPROVAL OF STATE PLANS Consent Findings and Summary Decisions § 1955.22 Summary...

  10. 76 FR 18064 - State of California; Request for Approval of Section 112(l) Authority for Hazardous Air...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-01

    ...). ACTION: Final rule. SUMMARY: EPA is finalizing approval of California's Airborne Toxic Control Measure... (75 FR 61662), EPA proposed to approve California's Airborne Toxic Control Measure for Emissions of...

  11. 78 FR 29780 - Fees for Testing, Evaluation, and Approval of Mining Products

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-21

    ... Approval of Mining Products AGENCY: Mine Safety and Health Administration, Labor. ACTION: Notice. SUMMARY..., and approval of mining products; it allows MSHA to collect fees up to $2,499,000 for the testing, evaluation, and approval of certain mining equipment. MSHA is continuing to collect these fees for 2013 as...

  12. 77 FR 69504 - Agency Information Collection Activities; Emergency Reinstatement of Previously Approved Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-19

    ... MERIT SYSTEMS PROTECTION BOARD Agency Information Collection Activities; Emergency Reinstatement of Previously Approved Collection AGENCY: Merit Systems Protection Board. ACTION: Notice of emergency reinstatement. SUMMARY: The Merit Systems Protection Board (MSPB) is requesting approval from the Office of...

  13. 77 FR 47544 - Approval of Classification Societies

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-09

    ...-AB35 Approval of Classification Societies AGENCY: Coast Guard, DHS. ACTION: Final rule. SUMMARY: Federal law requires that classification societies conducting certain work in the United States be... that classification societies must meet in order to obtain approval by the Coast Guard. Through this...

  14. A multistage crucible of revision and approval shapes IPCC policymaker summaries

    PubMed Central

    Mach, Katharine J.; Freeman, Patrick T.; Mastrandrea, Michael D.; Field, Christopher B.

    2016-01-01

    Intergovernmental Panel on Climate Change (IPCC) member governments approve each report’s summary for policymakers (SPM) by consensus, discussing and agreeing on each sentence in a plenary session with scientist authors. A defining feature of IPCC assessment, the governmental approval process builds joint ownership of current knowledge by scientists and governments. The resulting SPM revisions have been extensively discussed in anecdotes, interviews, and perspectives, but they have not been comprehensively analyzed. We provide an in-depth evaluation of IPCC SPM revisions, establishing an evidential basis for understanding their nature. Revisions associated with governmental review and approval generally expand SPMs, with SPM text growing by 17 to 53% across recent assessment reports. Cases of high political sensitivity and failure to reach consensus are notable exceptions, resulting in SPM contractions. In contrast to recent claims, we find that IPCC SPMs are as readable, for multiple metrics of reading ease, as other professionally edited assessment summaries. Across reading-ease metrics, some SPMs become more readable through governmental review and approval, whereas others do not. In an SPM examined through the entire revision process, most revisions associated with governmental review and approval occurred before the start of the government-approval plenary session. These author revisions emphasize clarity, scientific rigor, and explanation. In contrast, the subsequent plenary revisions place greater emphasis especially on policy relevance, comprehensiveness of examples, and nuances of expert judgment. Overall, the value added by the IPCC process emerges in a multistage crucible of revision and approval, as individuals together navigate complex science-policy terrain. PMID:27532046

  15. 78 FR 65573 - Migratory Bird Hunting; Application for Approval of Copper-Clad Iron Shot and Fluoropolymer Shot...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-01

    ... supported approval of the shot and the coatings, and one contained no useful information. Therefore, as... Hunting; Application for Approval of Copper-Clad Iron Shot and Fluoropolymer Shot Coatings as Nontoxic for... environmental assessments. SUMMARY: We, the U.S. Fish and Wildlife Service, approve copper-clad iron shot and...

  16. 78 FR 65982 - Information Collection Approved by the Office of Management and Budget (OMB)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-04

    ... FEDERAL COMMUNICATIONS COMMISSION Information Collection Approved by the Office of Management and Budget (OMB) AGENCY: Federal Communications Commission. ACTION: Notice. SUMMARY: The Federal Communications Commission (FCC) has received Office of Management and Budget (OMB) approval for the following...

  17. 75 FR 63474 - Public Information Collection Approved by Office of Management and Budget (OMB)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... FEDERAL COMMUNICATIONS COMMISSION Public Information Collection Approved by Office of Management and Budget (OMB) October 7, 2010. SUMMARY: The Federal Communications Commission (FCC) has received Office of Management and Budget (OMB) approval for the following public information collection pursuant...

  18. 77 FR 46760 - Information Collections Approved by the Office of Management and Budget

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-06

    ... Budget AGENCY: Federal Communications Commission. ACTION: Notice of public information collection approved by the Office of Management and Budget. SUMMARY: The Federal Communications Commission has received the Office of Management and Budget (OMB) approval for the following public information collection...

  19. 76 FR 69321 - Petition to Modify an Exemption of a Previously Approved Antitheft Device; Porsche

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-08

    ... DEPARTMENT OF TRANSPORTATION National Highway Traffic Safety Administration Petition to Modify an Exemption of a Previously Approved Antitheft Device; Porsche AGENCY: National Highway Traffic Safety... previously approved antitheft device. SUMMARY: On May 25, 1989, the National Highway Traffic Safety...

  20. 78 FR 68463 - Notice of Emergency Approval of an Information Collection: Regional Analysis of Impediments...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-14

    ... Approval of an Information Collection: Regional Analysis of Impediments Guidance for Sustainable Communities Grantees AGENCY: Office of the Chief Information Officer, HUD. ACTION: Notice. SUMMARY: In... Budget (OMB) emergency approval of the information collection described in this notice. DATES: Comments...

  1. 75 FR 59747 - Regular Board of Directors Meeting; Sunshine Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-28

    ..., DC 20005. Status: Open. Contact Person for More Information: Erica Hall, Assistant Corporate.... Summary Report of the Corporate Administration Committee. IV. Summary Report of the Corporate Administration Committee. V. Approval of the Minutes. VI. Summary Report of the Finance, Budget and Program...

  2. Drugs Approved for Neuroblastoma

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for neuroblastoma. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  3. 75 FR 50711 - Approval and Promulgation of Air Quality Implementation Plans; Ohio; Final Approval and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-17

    ... conditional approval of portions of OAC rule 3745-21-09. You can learn more information about the rule...). ACTION: Final rule. SUMMARY: Under section 110(k)(3) of the Clean Air Act (CAA), EPA is disapproving an...) of the CAA, we are also conditionally approving a revision of paragraph (BBB)(1) of OAC 3745-21-09...

  4. Drugs Approved for Retinoblastoma

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for retinoblastoma. The list includes generic names and brand names. The drug names link to NCI’s Cancer Drug Information summaries.

  5. 75 FR 61662 - State of California; Request for Approval of Section 112(l) Authority for Hazardous Air...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-06

    ...). ACTION: Proposed rule. SUMMARY: EPA is proposing to approve California's Airborne Toxic Control Measure... Resources Board (CARB) for approval to implement and enforce California's Airborne Toxic Control Measure for... Dry Cleaning ATCM California's Airborne Toxic Control Measure for Emissions of Perchloroethylene from...

  6. 78 FR 52893 - Approval and Promulgation of Implementation Plans; State of Iowa

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-27

    ... (EPA). ACTION: Proposed rule. SUMMARY: EPA is proposing to approve revisions to the State... Board of Health Rules and Regulations. These proposed revisions reflect updates to the Iowa statewide rules previously approved by EPA and will ensure consistency between the applicable local agency rules...

  7. 76 FR 50536 - Projects Approved or Rescinded for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-15

    ... SUSQUEHANNA RIVER BASIN COMMISSION Projects Approved or Rescinded for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: This notice lists the projects... the consumptive use of water pursuant to the Commission's approval by rule process set forth in 18 CFR...

  8. 76 FR 20802 - Projects Approved or Rescinded for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-13

    ... SUSQUEHANNA RIVER BASIN COMMISSION Projects Approved or Rescinded for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: This notice lists the projects... the consumptive use of water pursuant to the Commission's approval by rule process set forth in 18 CFR...

  9. 78 FR 70062 - Withdrawal of Approval of New Animal Drug Applications; Carbarsone; Roxarsone

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-22

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-N-0002] Withdrawal of Approval of New Animal Drug Applications; Carbarsone; Roxarsone AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is withdrawing approval of...

  10. 77 FR 13348 - Approval of VIP Chemical, Inc., As a Commercial Gauger

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-06

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Customs and Border Protection Approval of VIP Chemical, Inc., As a Commercial Gauger AGENCY: U.S. Customs and Border Protection, Department of Homeland Security. ACTION: Notice of approval of VIP Chemical, Inc., as a commercial gauger. SUMMARY: Notice is hereby given...

  11. 76 FR 49433 - Notice To Request an Extension and Revision of Currently Approved Information Collection and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-10

    ... Previously Approved Information Collection'' for volunteer workers (73 FR 62949). In accordance with the... request an extension for currently approved information collection, Volunteer Program-Earth Team. This..., for the Volunteer Interest and Placement Summary form and the Time Sheet form. The collected...

  12. 76 FR 14109 - Approval of Exemption From the Bond/Escrow Requirement Relating to the Sale of Assets by an...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-15

    ... PENSION BENEFIT GUARANTY CORPORATION Approval of Exemption From the Bond/Escrow Requirement... Express, LLC, and Texas Rangers Baseball Partners AGENCY: Pension Benefit Guaranty Corporation. ACTION: Notice of approval. SUMMARY: The Pension Benefit Guaranty Corporation has granted a request from Rangers...

  13. 78 FR 73915 - Notice of Request for Extension of Currently Approved Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-09

    ..., Enterprise Information Security & Policy. [FR Doc. 2013-29218 Filed 12-6-13; 8:45 am] BILLING CODE 8120-08-P ... TENNESSEE VALLEY AUTHORITY Notice of Request for Extension of Currently Approved Information... Currently Approved Information Collection. SUMMARY: The information collection described below will be...

  14. 78 FR 32233 - Notice of Request for Extension of Approval of an Information Collection; Importation of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-29

    ...] Notice of Request for Extension of Approval of an Information Collection; Importation of Artificially... an information collection; comment request. SUMMARY: In accordance with the Paperwork Reduction Act... an extension of approval of an information collection associated with the regulations for the...

  15. 77 FR 33394 - Notice of Intent To Request an Extension of a Currently Approved Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-06

    ... DEPARTMENT OF AGRICULTURE National Institute of Food and Agriculture Notice of Intent To Request... Agriculture, USDA. ACTION: Notice and request for comments. SUMMARY: In accordance with the Paperwork... Institute of Food and Agriculture's (NIFA) intention to request approval to extend the currently approved...

  16. 78 FR 13300 - Notice of Request for Extension of Approval of an Information Collection; Importation of Fruits...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-27

    ... Information Collection; Importation of Fruits and Vegetables AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION: Extension of approval of an information collection; comment request. SUMMARY: In... Inspection Service's intention to request an extension of approval of an information collection associated...

  17. 77 FR 2308 - Approval of Altol Petroleum Product Service, as a Commercial Gauger

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-17

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Customs and Border Protection Approval of Altol Petroleum... Security. ACTION: Notice of approval of Altol Petroleum Product Service, as a commercial gauger. SUMMARY: Notice is hereby given that, pursuant to 19 CFR 151.13, Altol Petroleum Product Service, Calle Gregorio...

  18. 45 CFR 1386.31 - State Plan submittal and approval.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... State Plan to significant comments and suggestions. A summary of the Council's response to State Plan.... (c) Failure to submit an approvable State plan or amendment prior to the Federal fiscal years for... eligible for Federal financial participation. (d) The Commissioner must approve any State plan or plan...

  19. 45 CFR 1386.31 - State Plan submittal and approval.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... State Plan to significant comments and suggestions. A summary of the Council's response to State Plan.... (c) Failure to submit an approvable State plan or amendment prior to the Federal fiscal years for... eligible for Federal financial participation. (d) The Commissioner must approve any State plan or plan...

  20. 45 CFR 1386.31 - State Plan submittal and approval.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... State Plan to significant comments and suggestions. A summary of the Council's response to State Plan.... (c) Failure to submit an approvable State plan or amendment prior to the Federal fiscal years for... eligible for Federal financial participation. (d) The Commissioner must approve any State plan or plan...

  1. 45 CFR 1386.31 - State Plan submittal and approval.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... State Plan to significant comments and suggestions. A summary of the Council's response to State Plan.... (c) Failure to submit an approvable State plan or amendment prior to the Federal fiscal years for... eligible for Federal financial participation. (d) The Commissioner must approve any State plan or plan...

  2. 45 CFR 1386.31 - State Plan submittal and approval.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... State Plan to significant comments and suggestions. A summary of the Council's response to State Plan.... (c) Failure to submit an approvable State plan or amendment prior to the Federal fiscal years for... eligible for Federal financial participation. (d) The Commissioner must approve any State plan or plan...

  3. 75 FR 8292 - Approval and Promulgation of Air Quality Implementation Plans; Virginia; Opacity Source...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-24

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R03-OAR-2010-0009; FRL-9115-8] Approval and Promulgation of Air Quality Implementation Plans; Virginia; Opacity Source Surveillance Methods AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA proposes to approve the State...

  4. 75 FR 17894 - Approval and Promulgation of Implementation Plans; New Mexico; Interstate Transport of Pollution

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-08

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R06-OAR-2007-0993; FRL-9134-7] Approval and Promulgation of Implementation Plans; New Mexico; Interstate Transport of Pollution AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is proposing to approve this State...

  5. 75 FR 33632 - Renewal of Approved Information Collection, OMB Control Number 1004-0179

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-14

    ... Approved Information Collection, OMB Control Number 1004-0179 AGENCY: Bureau of Land Management, Interior.... This information collection activity was previously approved by the OMB, and assigned control number...: Title: Helium Contracts (43 CFR part 3195). OMB Control Number: 1004-0179. Summary: This collection of...

  6. 29 CFR 1952.175 - Changes to approved plans.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., California's Small Employer Voluntary Compliance Program, implemented on March 1, 1981, was approved by the... on January 1, 1977, was approved by the Assistant Secretary on March 6, 1978. (b) On January 1, 1978... employee access to the employer's log and summary of occupational injuries and illnesses. (d) In accordance...

  7. 29 CFR 1952.175 - Changes to approved plans.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., California's Small Employer Voluntary Compliance Program, implemented on March 1, 1981, was approved by the... on January 1, 1977, was approved by the Assistant Secretary on March 6, 1978. (b) On January 1, 1978... employee access to the employer's log and summary of occupational injuries and illnesses. (d) In accordance...

  8. 77 FR 50576 - Fatigue Tolerance Evaluation of Metallic Structures; OMB Approval of Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-22

    ...-0413; Amdt. No. 29-55] RIN 2120-AJ51 Fatigue Tolerance Evaluation of Metallic Structures; OMB Approval of Information Collection AGENCY: Federal Aviation Administration, DOT. ACTION: Final rule; OMB approval of information collection. SUMMARY: This document notifies the public of the Office of Management...

  9. 77 FR 38638 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-28

    ... Control Number 0910-0342)--Revision I. Background Section 409 of the Federal Food, Drug, and Cosmetic Act... approval requirements based on a determination that such use is GRAS. The proposed regulations (proposed 21... notice would include a detailed summary of the data and information that support the GRAS determination...

  10. 76 FR 38221

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-29

    ... OPIC EXPEDITED SCREENING QUESTIONNAIRE DOWNSTREAM INVESTMENT FORM AGENCY: Overseas Private Investment Corporation (OPIC). ACTION: Request for approval from OMB. SUMMARY: Under the provisions of the... approved collection. Title: Expedited Screening Questionnaire (ESQ)--Downstream Investments. Form Number...

  11. Drugs Approved for Bone Cancer

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for bone cancer. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  12. Drugs Approved for Vulvar Cancer

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for vulvar cancer. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  13. Drugs Approved for Esophageal Cancer

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for esophageal cancer. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  14. Drugs Approved for Endometrial Cancer

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for endometrial cancer. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  15. Drugs Approved for Kaposi Sarcoma

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for Kaposi sarcoma. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  16. Drugs Approved for Malignant Mesothelioma

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for malignant mesothelioma. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  17. Drugs Approved for Skin Cancer

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for skin cancer. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  18. Drugs Approved for Gestational Trophoblastic Disease

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for gestational trophoblastic disease. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  19. Drugs Approved for Liver Cancer

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for liver cancer. The list includes generic names and brand names. The drug names link to NCI’s Cancer Drug Information summaries.

  20. Drugs Approved for Penile Cancer

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for penile cancer. The list includes generic names and brand names. The drug names link to NCI’s Cancer Drug Information summaries.

  1. Drugs Approved for Stomach (Gastric) Cancer

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for stomach (gastric) cancer. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  2. Drugs Approved for Vaginal Cancer

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) to prevent vaginal cancer. The list includes generic names and brand names. The drug names link to NCI’s Cancer Drug Information summaries.

  3. Drugs Approved for Soft Tissue Sarcoma

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for soft tissue sarcoma. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  4. CH-TRU Waste Content Codes (CH-TRUCON)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Washington TRU Solutions LLC

    2007-08-15

    The CH-TRU Waste Content Codes (CH-TRUCON) document describes the inventory of the U.S. Department of Energy (DOE) CH-TRU waste within the transportation parameters specified by the Contact-Handled Transuranic Waste Authorized Methods for Payload Control (CH-TRAMPAC). The CH-TRAMPAC defines the allowable payload for the Transuranic Package Transporter-II (TRUPACT-II) and HalfPACT packagings. This document is a catalog of TRUPACT-II and HalfPACT authorized contents and a description of the methods utilized to demonstrate compliance with the CH-TRAMPAC. A summary of currently approved content codes by site is presented in Table 1. The CH-TRAMPAC describes "shipping categories" that are assigned to each payload container.more » Multiple shipping categories may be assigned to a single content code. A summary of approved content codes and corresponding shipping categories is provided in Table 2, which consists of Tables 2A, 2B, and 2C. Table 2A provides a summary of approved content codes and corresponding shipping categories for the "General Case," which reflects the assumption of a 60-day shipping period as described in the CH-TRAMPAC and Appendix 3.4 of the CH-TRU Payload Appendices. For shipments to be completed within an approximately 1,000-mile radius, a shorter shipping period of 20 days is applicable as described in the CH-TRAMPAC and Appendix 3.5 of the CH-TRU Payload Appendices. For shipments to WIPP from Los Alamos National Laboratory (LANL), Nevada Test Site, and Rocky Flats Environmental Technology Site, a 20-day shipping period is applicable. Table 2B provides a summary of approved content codes and corresponding shipping categories for "Close-Proximity Shipments" (20-day shipping period). For shipments implementing the controls specified in the CH-TRAMPAC and Appendix 3.6 of the CH-TRU Payload Appendices, a 10-day shipping period is applicable. Table 2C provides a summary of approved content codes and corresponding shipping categories for "Controlled Shipments" (10-day shipping period).« less

  5. CH-TRU Waste Content Codes (CH-TRUCON)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Washington TRU Solutions LLC

    2007-06-15

    The CH-TRU Waste Content Codes (CH-TRUCON) document describes the inventory of the U.S. Department of Energy (DOE) CH-TRU waste within the transportation parameters specified by the Contact-Handled Transuranic Waste Authorized Methods for Payload Control (CH-TRAMPAC). The CH-TRAMPAC defines the allowable payload for the Transuranic Package Transporter-II (TRUPACT-II) and HalfPACT packagings. This document is a catalog of TRUPACT-II and HalfPACT authorized contents and a description of the methods utilized to demonstrate compliance with the CH-TRAMPAC. A summary of currently approved content codes by site is presented in Table 1. The CH-TRAMPAC describes "shipping categories" that are assigned to each payload container.more » Multiple shipping categories may be assigned to a single content code. A summary of approved content codes and corresponding shipping categories is provided in Table 2, which consists of Tables 2A, 2B, and 2C. Table 2A provides a summary of approved content codes and corresponding shipping categories for the "General Case," which reflects the assumption of a 60-day shipping period as described in the CH-TRAMPAC and Appendix 3.4 of the CH-TRU Payload Appendices. For shipments to be completed within an approximately 1,000-mile radius, a shorter shipping period of 20 days is applicable as described in the CH-TRAMPAC and Appendix 3.5 of the CH-TRU Payload Appendices. For shipments to WIPP from Los Alamos National Laboratory (LANL), Nevada Test Site, and Rocky Flats Environmental Technology Site, a 20-day shipping period is applicable. Table 2B provides a summary of approved content codes and corresponding shipping categories for "Close-Proximity Shipments" (20-day shipping period). For shipments implementing the controls specified in the CH-TRAMPAC and Appendix 3.6 of the CH-TRU Payload Appendices, a 10-day shipping period is applicable. Table 2C provides a summary of approved content codes and corresponding shipping categories for "Controlled Shipments" (10-day shipping period).« less

  6. CH-TRU Waste Content Codes (CH-TRUCON)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Washington TRU Solutions LLC

    2007-09-20

    The CH-TRU Waste Content Codes (CH-TRUCON) document describes the inventory of the U.S. Department of Energy (DOE) CH-TRU waste within the transportation parameters specified by the Contact-Handled Transuranic Waste Authorized Methods for Payload Control (CH-TRAMPAC). The CH-TRAMPAC defines the allowable payload for the Transuranic Package Transporter-II (TRUPACT-II) and HalfPACT packagings. This document is a catalog of TRUPACT-II and HalfPACT authorized contents and a description of the methods utilized to demonstrate compliance with the CH-TRAMPAC. A summary of currently approved content codes by site is presented in Table 1. The CH-TRAMPAC describes "shipping categories" that are assigned to each payload container.more » Multiple shipping categories may be assigned to a single content code. A summary of approved content codes and corresponding shipping categories is provided in Table 2, which consists of Tables 2A, 2B, and 2C. Table 2A provides a summary of approved content codes and corresponding shipping categories for the "General Case," which reflects the assumption of a 60-day shipping period as described in the CH-TRAMPAC and Appendix 3.4 of the CH-TRU Payload Appendices. For shipments to be completed within an approximately 1,000-mile radius, a shorter shipping period of 20 days is applicable as described in the CH-TRAMPAC and Appendix 3.5 of the CH-TRU Payload Appendices. For shipments to WIPP from Los Alamos National Laboratory (LANL), Nevada Test Site, and Rocky Flats Environmental Technology Site, a 20-day shipping period is applicable. Table 2B provides a summary of approved content codes and corresponding shipping categories for "Close-Proximity Shipments" (20-day shipping period). For shipments implementing the controls specified in the CH-TRAMPAC and Appendix 3.6 of the CH-TRU Payload Appendices, a 10-day shipping period is applicable. Table 2C provides a summary of approved content codes and corresponding shipping categories for "Controlled Shipments" (10-day shipping period).« less

  7. CH-TRU Waste Content Codes (CH-TRUCON)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Washington TRU Solutions LLC

    2006-06-20

    The CH-TRU Waste Content Codes (CH-TRUCON) document describes the inventory of the U.S. Department of Energy (DOE) CH-TRU waste within the transportation parameters specified by the Contact-Handled Transuranic Waste Authorized Methods for Payload Control (CH-TRAMPAC). The CH-TRAMPAC defines the allowable payload for the Transuranic Package Transporter-II (TRUPACT-II) and HalfPACT packagings. This document is a catalog of TRUPACT-II and HalfPACT authorized contents and a description of the methods utilized to demonstrate compliance with the CH-TRAMPAC. A summary of currently approved content codes by site is presented in Table 1. The CH-TRAMPAC describes "shipping categories" that are assigned to each payload container.more » Multiple shipping categories may be assigned to a single content code. A summary of approved content codes and corresponding shipping categories is provided in Table 2, which consists of Tables 2A, 2B, and 2C. Table 2A provides a summary of approved content codes and corresponding shipping categories for the "General Case," which reflects the assumption of a 60-day shipping period as described in the CH-TRAMPAC and Appendix 3.4 of the CH-TRU Payload Appendices. For shipments to be completed within an approximately 1,000-mile radius, a shorter shipping period of 20 days is applicable as described in the CH-TRAMPAC and Appendix 3.5 of the CH-TRU Payload Appendices. For shipments to WIPP from Los Alamos National Laboratory (LANL), Nevada Test Site, and Rocky Flats Environmental Technology Site, a 20-day shipping period is applicable. Table 2B provides a summary of approved content codes and corresponding shipping categories for "Close-Proximity Shipments" (20-day shipping period). For shipments implementing the controls specified in the CH-TRAMPAC and Appendix 3.6 of the CH-TRU Payload Appendices, a 10-day shipping period is applicable. Table 2C provides a summary of approved content codes and corresponding shipping categories for "Controlled Shipments" (10-day shipping period).« less

  8. CH-TRU Waste Content Codes (CH-TRUCON)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Washington TRU Solutions LLC

    2006-01-18

    The CH-TRU Waste Content Codes (CH-TRUCON) document describes the inventory of the U.S. Department of Energy (DOE) CH-TRU waste within the transportation parameters specified by the Contact-Handled Transuranic Waste Authorized Methods for Payload Control (CH-TRAMPAC). The CH-TRAMPAC defines the allowable payload for the Transuranic Package Transporter-II (TRUPACT-II) and HalfPACT packagings. This document is a catalog of TRUPACT-II and HalfPACT authorized contents and a description of the methods utilized to demonstrate compliance with the CH-TRAMPAC. A summary of currently approved content codes by site is presented in Table 1. The CH-TRAMPAC describes "shipping categories" that are assigned to each payload container.more » Multiple shipping categories may be assigned to a single content code. A summary of approved content codes and corresponding shipping categories is provided in Table 2, which consists of Tables 2A, 2B, and 2C. Table 2A provides a summary of approved content codes and corresponding shipping categories for the "General Case," which reflects the assumption of a 60-day shipping period as described in the CH-TRAMPAC and Appendix 3.4 of the CH-TRU Payload Appendices. For shipments to be completed within an approximately 1,000-mile radius, a shorter shipping period of 20 days is applicable as described in the CH-TRAMPAC and Appendix 3.5 of the CH-TRU Payload Appendices. For shipments to WIPP from Los Alamos National Laboratory (LANL), Nevada Test Site, and Rocky Flats Environmental Technology Site, a 20-day shipping period is applicable. Table 2B provides a summary of approved content codes and corresponding shipping categories for "Close-Proximity Shipments" (20-day shipping period). For shipments implementing the controls specified in the CH-TRAMPAC and Appendix 3.6 of the CH-TRU Payload Appendices, a 10-day shipping period is applicable. Table 2C provides a summary of approved content codes and corresponding shipping categories for "Controlled Shipments" (10-day shipping period).« less

  9. CH-TRU Waste Content Codes (CH-TRUCON)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Washington TRU Solutions LLC

    2006-08-15

    The CH-TRU Waste Content Codes (CH-TRUCON) document describes the inventory of the U.S. Department of Energy (DOE) CH-TRU waste within the transportation parameters specified by the Contact-Handled Transuranic Waste Authorized Methods for Payload Control (CH-TRAMPAC). The CH-TRAMPAC defines the allowable payload for the Transuranic Package Transporter-II (TRUPACT-II) and HalfPACT packagings. This document is a catalog of TRUPACT-II and HalfPACT authorized contents and a description of the methods utilized to demonstrate compliance with the CH-TRAMPAC. A summary of currently approved content codes by site is presented in Table 1. The CH-TRAMPAC describes "shipping categories" that are assigned to each payload container.more » Multiple shipping categories may be assigned to a single content code. A summary of approved content codes and corresponding shipping categories is provided in Table 2, which consists of Tables 2A, 2B, and 2C. Table 2A provides a summary of approved content codes and corresponding shipping categories for the "General Case," which reflects the assumption of a 60-day shipping period as described in the CH-TRAMPAC and Appendix 3.4 of the CH-TRU Payload Appendices. For shipments to be completed within an approximately 1,000-mile radius, a shorter shipping period of 20 days is applicable as described in the CH-TRAMPAC and Appendix 3.5 of the CH-TRU Payload Appendices. For shipments to WIPP from Los Alamos National Laboratory (LANL), Nevada Test Site, and Rocky Flats Environmental Technology Site, a 20-day shipping period is applicable. Table 2B provides a summary of approved content codes and corresponding shipping categories for "Close-Proximity Shipments" (20-day shipping period). For shipments implementing the controls specified in the CH-TRAMPAC and Appendix 3.6 of the CH-TRU Payload Appendices, a 10-day shipping period is applicable. Table 2C provides a summary of approved content codes and corresponding shipping categories for "Controlled Shipments" (10-day shipping period).« less

  10. CH-TRU Waste Content Codes (CH-TRUCON)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Washington TRU Solutions LLC

    2006-12-20

    The CH-TRU Waste Content Codes (CH-TRUCON) document describes the inventory of the U.S. Department of Energy (DOE) CH-TRU waste within the transportation parameters specified by the Contact-Handled Transuranic Waste Authorized Methods for Payload Control (CH-TRAMPAC). The CH-TRAMPAC defines the allowable payload for the Transuranic Package Transporter-II (TRUPACT-II) and HalfPACT packagings. This document is a catalog of TRUPACT-II and HalfPACT authorized contents and a description of the methods utilized to demonstrate compliance with the CH-TRAMPAC. A summary of currently approved content codes by site is presented in Table 1. The CH-TRAMPAC describes "shipping categories" that are assigned to each payload container.more » Multiple shipping categories may be assigned to a single content code. A summary of approved content codes and corresponding shipping categories is provided in Table 2, which consists of Tables 2A, 2B, and 2C. Table 2A provides a summary of approved content codes and corresponding shipping categories for the "General Case," which reflects the assumption of a 60-day shipping period as described in the CH-TRAMPAC and Appendix 3.4 of the CH-TRU Payload Appendices. For shipments to be completed within an approximately 1,000-mile radius, a shorter shipping period of 20 days is applicable as described in the CH-TRAMPAC and Appendix 3.5 of the CH-TRU Payload Appendices. For shipments to WIPP from Los Alamos National Laboratory (LANL), Nevada Test Site, and Rocky Flats Environmental Technology Site, a 20-day shipping period is applicable. Table 2B provides a summary of approved content codes and corresponding shipping categories for "Close-Proximity Shipments" (20-day shipping period). For shipments implementing the controls specified in the CH-TRAMPAC and Appendix 3.6 of the CH-TRU Payload Appendices, a 10-day shipping period is applicable. Table 2C provides a summary of approved content codes and corresponding shipping categories for "Controlled Shipments" (10-day shipping period).« less

  11. CH-TRU Waste Content Codes (CH-TRUCON)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Washington TRU Solutions LLC

    2007-02-15

    The CH-TRU Waste Content Codes (CH-TRUCON) document describes the inventory of the U.S. Department of Energy (DOE) CH-TRU waste within the transportation parameters specified by the Contact-Handled Transuranic Waste Authorized Methods for Payload Control (CH-TRAMPAC). The CH-TRAMPAC defines the allowable payload for the Transuranic Package Transporter-II (TRUPACT-II) and HalfPACT packagings. This document is a catalog of TRUPACT-II and HalfPACT authorized contents and a description of the methods utilized to demonstrate compliance with the CH-TRAMPAC. A summary of currently approved content codes by site is presented in Table 1. The CH-TRAMPAC describes "shipping categories" that are assigned to each payload container.more » Multiple shipping categories may be assigned to a single content code. A summary of approved content codes and corresponding shipping categories is provided in Table 2, which consists of Tables 2A, 2B, and 2C. Table 2A provides a summary of approved content codes and corresponding shipping categories for the "General Case," which reflects the assumption of a 60-day shipping period as described in the CH-TRAMPAC and Appendix 3.4 of the CH-TRU Payload Appendices. For shipments to be completed within an approximately 1,000-mile radius, a shorter shipping period of 20 days is applicable as described in the CH-TRAMPAC and Appendix 3.5 of the CH-TRU Payload Appendices. For shipments to WIPP from Los Alamos National Laboratory (LANL), Nevada Test Site, and Rocky Flats Environmental Technology Site, a 20-day shipping period is applicable. Table 2B provides a summary of approved content codes and corresponding shipping categories for "Close-Proximity Shipments" (20-day shipping period). For shipments implementing the controls specified in the CH-TRAMPAC and Appendix 3.6 of the CH-TRU Payload Appendices, a 10-day shipping period is applicable. Table 2C provides a summary of approved content codes and corresponding shipping categories for "Controlled Shipments" (10-day shipping period).« less

  12. CH-TRU Waste Content Codes (CH-TRUCON)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Washington TRU Solutions LLC

    2006-09-15

    The CH-TRU Waste Content Codes (CH-TRUCON) document describes the inventory of the U.S. Department of Energy (DOE) CH-TRU waste within the transportation parameters specified by the Contact-Handled Transuranic Waste Authorized Methods for Payload Control (CH-TRAMPAC). The CH-TRAMPAC defines the allowable payload for the Transuranic Package Transporter-II (TRUPACT-II) and HalfPACT packagings. This document is a catalog of TRUPACT-II and HalfPACT authorized contents and a description of the methods utilized to demonstrate compliance with the CH-TRAMPAC. A summary of currently approved content codes by site is presented in Table 1. The CH-TRAMPAC describes "shipping categories" that are assigned to each payload container.more » Multiple shipping categories may be assigned to a single content code. A summary of approved content codes and corresponding shipping categories is provided in Table 2, which consists of Tables 2A, 2B, and 2C. Table 2A provides a summary of approved content codes and corresponding shipping categories for the "General Case," which reflects the assumption of a 60-day shipping period as described in the CH-TRAMPAC and Appendix 3.4 of the CH-TRU Payload Appendices. For shipments to be completed within an approximately 1,000-mile radius, a shorter shipping period of 20 days is applicable as described in the CH-TRAMPAC and Appendix 3.5 of the CH-TRU Payload Appendices. For shipments to WIPP from Los Alamos National Laboratory (LANL), Nevada Test Site, and Rocky Flats Environmental Technology Site, a 20-day shipping period is applicable. Table 2B provides a summary of approved content codes and corresponding shipping categories for "Close-Proximity Shipments" (20-day shipping period). For shipments implementing the controls specified in the CH-TRAMPAC and Appendix 3.6 of the CH-TRU Payload Appendices, a 10-day shipping period is applicable. Table 2C provides a summary of approved content codes and corresponding shipping categories for "Controlled Shipments" (10-day shipping period).« less

  13. CH-TRU Waste Content Codes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Washington TRU Solutions LLC

    2008-01-16

    The CH-TRU Waste Content Codes (CH-TRUCON) document describes the inventory of the U.S. Department of Energy (DOE) CH-TRU waste within the transportation parameters specified by the Contact-Handled Transuranic Waste Authorized Methods for Payload Control (CH-TRAMPAC). The CH-TRAMPAC defines the allowable payload for the Transuranic Package Transporter-II (TRUPACT-II) and HalfPACT packagings. This document is a catalog of TRUPACT-II and HalfPACT authorized contents and a description of the methods utilized to demonstrate compliance with the CH-TRAMPAC. A summary of currently approved content codes by site is presented in Table 1. The CH-TRAMPAC describes "shipping categories" that are assigned to each payload container.more » Multiple shipping categories may be assigned to a single content code. A summary of approved content codes and corresponding shipping categories is provided in Table 2, which consists of Tables 2A, 2B, and 2C. Table 2A provides a summary of approved content codes and corresponding shipping categories for the "General Case," which reflects the assumption of a 60-day shipping period as described in the CH-TRAMPAC and Appendix 3.4 of the CH-TRU Payload Appendices. For shipments to be completed within an approximately 1,000-mile radius, a shorter shipping period of 20 days is applicable as described in the CH-TRAMPAC and Appendix 3.5 of the CH-TRU Payload Appendices. For shipments to WIPP from Los Alamos National Laboratory (LANL), Nevada Test Site, and Rocky Flats Environmental Technology Site, a 20-day shipping period is applicable. Table 2B provides a summary of approved content codes and corresponding shipping categories for "Close-Proximity Shipments" (20-day shipping period). For shipments implementing the controls specified in the CH-TRAMPAC and Appendix 3.6 of the CH-TRU Payload Appendices, a 10-day shipping period is applicable. Table 2C provides a summary of approved content codes and corresponding shipping categories for "Controlled Shipments" (10-day shipping period).« less

  14. 78 FR 5346 - Approval and Promulgation of Air Quality Implementation Plans; Massachusetts and New Hampshire...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-25

    ...-FRL-9754-7] Approval and Promulgation of Air Quality Implementation Plans; Massachusetts and New... (EPA). ACTION: Proposed rule. SUMMARY: EPA is proposing to approve State Implementation Plan (SIP... repair network for an on-board diagnostic (OBD2) testing program for model year 1996 and newer vehicles...

  15. 78 FR 70566 - Withdrawal of Approval of New Animal Drug Applications; Arsanilic Acid

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-26

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-N-0002] Withdrawal of Approval of New Animal Drug Applications; Arsanilic Acid AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is withdrawing approval of a new...

  16. 76 FR 42557 - Approval and Promulgation of Air Quality Implementation Plans; Delaware; Regional Haze State...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-19

    ... Promulgation of Air Quality Implementation Plans; Delaware; Regional Haze State Implementation Plan AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY: EPA is approving the Delaware Regional Haze... visibility in mandatory Class I areas through a regional haze program. EPA is also approving this revision...

  17. 76 FR 50183 - Western Pacific Fisheries; Approval of a Marine Conservation Plan for the Northern Mariana Islands

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-12

    ... Pacific Fisheries; Approval of a Marine Conservation Plan for the Northern Mariana Islands AGENCY.... ACTION: Notice of agency decision. SUMMARY: NMFS announces approval of a marine conservation plan for the...-Stevens Fishery Conservation and Management Act (Magnuson-Stevens Act) authorizes the Secretary of State...

  18. 78 FR 15383 - Approval of Direct Transfer of Licenses and Issuance of License Amendment To Effectuate Such...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-11

    ... NUCLEAR REGULATORY COMMISSION [Docket Nos. 70-7003 and 70-7004; NRC-2010-0355] Approval of Direct... Operating, LLC AGENCY: Nuclear Regulatory Commission. ACTION: Notice of approval of direct transfer of control and issuance of license amendments to effectuate such transfers. SUMMARY: The U.S. Nuclear...

  19. 78 FR 61322 - Notice of Request for Extension of Approval of an Information Collection; Importation of Fresh...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-03

    ...] Notice of Request for Extension of Approval of an Information Collection; Importation of Fresh Baby Kiwi... an information collection; comment request. SUMMARY: In accordance with the Paperwork Reduction Act... an extension of approval of an information collection associated with the regulations for the...

  20. 77 FR 75183 - Approval of Intertek USA, Inc., as a Commercial Gauger

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-19

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Customs and Border Protection Approval of Intertek USA, Inc.... ACTION: Notice of approval of Intertek USA, Inc., as a commercial gauger. SUMMARY: Notice is hereby given that, pursuant to 19 CFR 151.13, Intertek USA, Inc., 139 Castle Coakley, Suite 8, St. Croix, VI 00820...

  1. 77 FR 39983 - Migratory Bird Hunting; Application for Approval of Fluoropolymeric Shot Coatings as Nontoxic for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-06

    ... of Fluoropolymeric Shot Coatings as Nontoxic for Waterfowl Hunting AGENCY: Fish and Wildlife Service, Interior. ACTION: Notice of application for nontoxic shot approval. SUMMARY: We, the U.S. Fish and Wildlife Service, announce that Spectra Shot, LLC, of Lafayette, Louisiana, has applied for approval of steel shot...

  2. 76 FR 14602 - Approval and Promulgation of Air Quality Implementation Plans; Louisiana; Revisions To Control...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-17

    ... Promulgation of Air Quality Implementation Plans; Louisiana; Revisions To Control Volatile Organic Compound...: Proposed rule. SUMMARY: EPA is proposing to approve State Implementation Plan (SIP) revisions for control... submitted to EPA on August 31, 2010. EPA is also proposing to approve a SIP revision for control of emission...

  3. Drugs Approved for Gastrointestinal Stromal Tumors

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for gastrointestinal stromal tumors (GIST). The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  4. Available Tools to Facilitate Early Patient Access to Medicines in the EU and the USA: Analysis of Conditional Approvals and the Implications for Personalized Medicine.

    PubMed

    Leyens, Lada; Richer, Étienne; Melien, Øyvind; Ballensiefen, Wolfgang; Brand, Angela

    2015-01-01

    Scientific knowledge and our understanding of the human body and diseases have limited any possible treatment tailoring to each patient. The technological advances enabling the integration of various data sets (e.g. '-omics', microbiome, epigenetics and environmental exposure) have facilitated a greater understanding of the human body, the molecular basis of disease and all the factors influencing disease onset, progression and response to treatment, thereby ushering in the era of personalized medicine. We evaluate the regulatory approaches available to facilitate early patient access to efficacious and safe compounds in the EU and the USA in order to make more informed recommendations in the future as to the gaps in regulations for early patient access. An in-depth analysis of conditional approvals (EU) and accelerated approvals (USA) is performed based on the publicly available information (European public assessment reports and a summary review of products approved under both programmes). The types of product, indications, time to approval and type of evidence submitted were analysed. Between 2007 and early 2015, 17 products were conditionally approved in the EU and 25 in the USA, most of them in the area of oncology and based on evidence from phase II clinical trial data. Early approval of promising products based on data from early phases of development is already possible in the EU and the USA. Some of the improvements could entail implementing a rolling assessment of evidence in Europe and extending the scope of early dialogues. © 2015 S. Karger AG, Basel.

  5. Drugs Approved for Leukemia

    Cancer.gov

    This page lists cancer drugs approved by the FDA for use in leukemia. The drug names link to NCI's Cancer Drug Information summaries. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters.

  6. 77 FR 35690 - Medical Devices; Availability of Safety and Effectiveness Summaries for Premarket Approval...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-14

    ... ADVIA Centaur Anti- January 20, 2012. Diagnostics Inc. HBs2 Assay and Quality Control Material. P100005... Flowonix Medical, Prometra February 7, 2012. Inc. (approved under Programmable Medasys, Inc.). Infusion...

  7. Drugs Approved for Wilms Tumor

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for Wilms tumor and other childhood kidney cancers. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  8. Drugs Approved for Head and Neck Cancer

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for head and neck cancer. The list includes generic names and brand names. The drug names link to NCI’s Cancer Drug Information summaries.

  9. 78 FR 54200 - Approval and Promulgation of Air Quality Implementation Plans; Indiana; Maintenance Plan Update...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-03

    ... County, Indiana for Sulfur Dioxide AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is proposing to approve a maintenance plan update for the Lake County, Indiana sulfur dioxide...

  10. USDOT guidance summary for connected vehicle deployments : human use approval.

    DOT National Transportation Integrated Search

    2016-07-01

    This document provides guidance material in regards to human use approval required for the CV Pilots DeploymentConcept Development Phase. Background is provided on relevant Federal guidance and Institutional Review Boards,including specific reference...

  11. 76 FR 39797 - Approval and Promulgation of Implementation Plans; Connecticut; Infrastructure SIP for the 1997 8...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-07

    .... SUMMARY: EPA is proposing to conditionally approve one element of Connecticut's December 28, 2007... commonly referred to as an infrastructure SIP. The one element of the submittal that EPA is proposing to... conditionally approving one element of Connecticut's December 28, 2007 submittal to meet the Clean Air Act...

  12. 75 FR 47817 - Notice of Availability: Test Tools and Test Procedures Approved for the Office of the National...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-09

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Notice of Availability: Test Tools and Test Procedures.... SUMMARY: This notice announces the availability of test tools and test procedures approved by the National... certification program. The approved test tools and test procedures are identified on the ONC Web site at: http...

  13. 78 FR 52429 - New Animal Drugs; Withdrawal of Approval of New Animal Drug Applications; Diethylcarbamazine...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-23

    ... 558 [Docket No. FDA-2013-N-0839] New Animal Drugs; Withdrawal of Approval of New Animal Drug...: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations to reflect the withdrawal of approval of three new animal drug applications (NADAs) at the sponsors' request...

  14. 77 FR 36980 - Migratory Bird Hunting; Application for Approval of Copper-Clad Iron Shot as Nontoxic for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-20

    ... of Copper-Clad Iron Shot as Nontoxic for Waterfowl Hunting AGENCY: Fish and Wildlife Service, Interior. ACTION: Notice of application for nontoxic shot approval. SUMMARY: We, the U.S. Fish and Wildlife Service, announce that Environ- Metal, Inc., of Sweet Home, Oregon, has applied for our approval of shot...

  15. 77 FR 15267 - Clean Air Act Full Approval of Title V Operating Permits Program; Southern Ute Indian Tribe

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-15

    ... Full Approval of Title V Operating Permits Program; Southern Ute Indian Tribe AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY: The EPA is promulgating full approval of the Title V Operating Permits Program submitted by the Southern Ute Indian Tribe (Tribe). The Tribe's Title V Operating...

  16. 78 FR 7672 - Approval and Promulgation of Implementation Plans; Texas; Beaumont/Port Arthur Ozone Maintenance...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-04

    .... SUMMARY: EPA is approving a revision to the Beaumont/Port Arthur (BPA) 1997 8-hour ozone maintenance air... emissions model. The BPA 1997 8-hour ozone maintenance area consists of Hardin, Jefferson, and Orange... proposed to approve a revision to the BPA 1997 8-hour ozone maintenance air quality SIP by replacing the...

  17. 77 FR 41680 - Indiana Regulatory Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-16

    ... DEPARTMENT OF THE INTERIOR Office of Surface Mining Reclamation and Enforcement 30 CFR Part 914... Mining Reclamation and Enforcement, Interior. ACTION: Final rule; approval of amendment. SUMMARY: We, the Office of Surface Mining Reclamation and Enforcement (OSM), are approving amendments to the Indiana...

  18. 75 FR 21212 - Approval of Classification Societies

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-23

    ...-AB35 Approval of Classification Societies AGENCY: Coast Guard, DHS. ACTION: Notice of proposed rulemaking. SUMMARY: Congress requires that classification societies conducting certain work in the United States must either be full members of International Association of Classification Societies (IACS) or...

  19. Drugs Approved for Testicular Cancer

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for testicular cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.

  20. Drugs Approved for Cervical Cancer

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for cervical cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.

  1. Drugs Approved for Rhabdomyosarcoma

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for rhabdomyosarcoma. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries. There may be drugs used in rhabdomyosarcoma that are not listed here.

  2. Drugs Approved for Hodgkin Lymphoma

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for Hodgkin lymphoma. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.

  3. Drugs Approved for Myeloproliferative Neoplasms

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for myeloproliferative neoplasms. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.

  4. Social Climate Indicators for the U.S. Army

    DTIC Science & Technology

    1991-08-01

    based on a secondary analysis of the 1978 Army Life study . Sample: Subjects from 8,1.40 personnel assigned to 60 different battalions. Summary...disillusionment: Its effect on Urion inthe nited States Navy. (AD-A127 311). Monterey, CA: Naval Postgraduate School. Description: This study ... ON AUTHORIlY 3. DISTRIBUTION/AVAILABILiTY OF REPORT --. _Approved for public releas,’ 1b. DECLASSIFICATION/DOWNGRADING SCHEDULE distribution is

  5. Subtyping of Toddlers with ASD Based on Patterns of Social Attention Deficits

    DTIC Science & Technology

    2015-10-30

    autism spectrum . Initial major tasks of the research project included regulatory review and approval and preparation of the eye tracking experiment...situation, we need to discover how to better classify and categorize patterns of behavior and development within the autism spectrum . Our subgrouping...and clinically relevant subgroups within the autism spectrum . Summary of Results, Progress, and Accomplishments with Discussion: Initial major

  6. [Twenty-year History and Future Challenges in Transparency Enhancement of Review Process for Approval: Focus on Public Release of Review Reports regarding New Drugs and Medical Devices].

    PubMed

    Morimoto, Kazushige; Kawasaki, Satoko; Yoshida, Yasunori

    2015-01-01

    For 20 years, the Ministry of Health, Labour and Welfare (MHLW, formerly Ministry of Health and Welfare (MHW)) has been trying to increase transparency of the review process for approving reports in order to promote the rational use of newly approved drugs and medical devices. The first Summary Basis of Approval (SBA) was published by MHW in 1994. In 1999, evaluation reports were prepared by MHW and the Pharmaceuticals and Medical Devices Evaluation Center to make them available to the public. In 2005, a notice from the Chief Executive of the Pharmaceuticals and Medical Devices Agency (PMDA) made procedures for public release of information on reviewing applications for new drugs. In 2006, 90 review reports of newly approved drugs and eight medical devices were revealed on PMDA websites. The dissemination of information by the United States Food and Drug Administration (FDA) and that of the European Medicines Agency (EMA) were studied and compared with that of the MHLW and PMDA. While common technical documents (CTD) for new drugs and summary technical documents (STED) for new medical devices have been released by PMDA, such documents are not released by the FDA and EMA. The European Public Assessment Report (EAPR) summary for the public is an interesting questionnaire approach that uses the "What," "How" and "Why" format. Finally, future proposals for the next decade are also outlined.

  7. 76 FR 9642 - Alabama Regulatory Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-22

    ... DEPARTMENT OF THE INTERIOR Office of Surface Mining Reclamation and Enforcement 30 CFR Part 901... Mining Reclamation and Enforcement, Interior. ACTION: Final rule; approval of amendment. SUMMARY: We, the Office of Surface Mining Reclamation and Enforcement (OSM), are approving an amendment to the Alabama...

  8. 78 FR 11579 - Texas Regulatory Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-19

    ... DEPARTMENT OF THE INTERIOR Office of Surface Mining Reclamation and Enforcement 30 CFR Part 943... Mining Reclamation and Enforcement, Interior. ACTION: Final rule; approval of amendment. SUMMARY: We, the Office of Surface Mining Reclamation and Enforcement (OSM), are approving an amendment to the Texas...

  9. 77 FR 8144 - Texas Regulatory Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-14

    ... DEPARTMENT OF THE INTERIOR Office of Surface Mining Reclamation and Enforcement 30 CFR Part 943... AGENCY: Office of Surface Mining Reclamation and Enforcement, Interior. ACTION: Final rule; approval of amendment. SUMMARY: We, the Office of Surface Mining Reclamation and Enforcement (OSM), are approving three...

  10. 78 FR 9807 - Utah Regulatory Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-12

    ... DEPARTMENT OF THE INTERIOR Office of Surface Mining Reclamation and Enforcement 30 CFR Part 944... Mining Reclamation and Enforcement, Interior. ACTION: Final rule; approval of amendment. SUMMARY: We are approving an amendment to the Utah regulatory program (the ``Utah program'') under the Surface Mining...

  11. 76 FR 30008 - Alabama Regulatory Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-24

    ... DEPARTMENT OF THE INTERIOR Office of Surface Mining Reclamation and Enforcement 30 CFR Part 901... Mining Reclamation and Enforcement, Interior. ACTION: Final rule; approval of amendment. SUMMARY: We, the Office of Surface Mining Reclamation and Enforcement (OSM), are approving an amendment to the Alabama...

  12. 78 FR 18593 - Information Collection; Information Regarding Responsibility Matters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-27

    ... ADMINISTRATION [OMB Control No. 9000-0174; Docket 2012-0076; Sequence 64] Information Collection; Information... comments regarding an existing OMB information clearance. SUMMARY: Under the provisions of the Paperwork... request to review and approve an extension of a previously approved information collection requirement...

  13. 75 FR 17462 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-06

    ... decision may be purchased by contacting the office of Public Assistance, Governmental Affairs, and...-2)] Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the second quarter 2010 Rail Cost...

  14. 75 FR 81122 - Texas Regulatory Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-27

    ... DEPARTMENT OF THE INTERIOR Office of Surface Mining Reclamation and Enforcement 30 CFR Part 943... Mining Reclamation and Enforcement, Interior. ACTION: Final rule; approval of amendment. SUMMARY: We, the Office of Surface Mining Reclamation and Enforcement (OSM), are approving an amendment to the Texas...

  15. 78 FR 18230 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-26

    ... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France... approved by the aviation authority of France and is approved for operation in the United States. Pursuant...

  16. 78 FR 25380 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-01

    ... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France... Determination These helicopters have been approved by the aviation authority of France and are approved for...

  17. 78 FR 857 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-07

    ... Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France (Eurocopter... been approved by the aviation authority of France and are approved for operation in the United States...

  18. 77 FR 58025 - Texas Regulatory Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-19

    ... DEPARTMENT OF THE INTERIOR Office of Surface Mining Reclamation and Enforcement 30 CFR Part 943... Mining Reclamation and Enforcement, Interior. ACTION: Final rule; approval of amendment. SUMMARY: We, the Office of Surface Mining Reclamation and Enforcement (OSM), are approving an amendment to the Texas...

  19. 78 FR 71724 - Recordations, Water Carrier Tariffs, and Agricultural Contract Summaries

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-29

    ... DEPARTMENT OF TRANSPORTATION Surface Transportation Board Recordations, Water Carrier Tariffs, and Agricultural Contract Summaries AGENCY: Surface Transportation Board, DOT. ACTION: Notice of OMB Approval of..., Control Number 2140-0025 (2) Water Carrier Tariffs, Control Number 2140-26 (3) Agricultural Contract...

  20. 77 FR 8865 - Recent Postings of Broadly Applicable Alternative Test Methods

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-15

    ... Applicable Alternative Test Methods AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of availability. SUMMARY: This notice announces the broadly applicable alternative test method approval decisions... INFORMATION CONTACT: An electronic copy of each alternative test method approval document is available on the...

  1. 75 FR 7593 - Recent Postings of Broadly Applicable Alternative Test Methods

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-22

    ... Applicable Alternative Test Methods AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of availability. SUMMARY: This notice announces the broadly applicable alternative test method approval decisions... electronic copy of each alternative test method approval document is available on EPA's Web site at http...

  2. 78 FR 11174 - Recent Postings of Broadly Applicable Alternative Test Methods

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-15

    ... Applicable Alternative Test Methods AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of availability. SUMMARY: This notice announces the broadly applicable alternative test method approval decisions... INFORMATION CONTACT: An electronic copy of each alternative test method approval document is available on the...

  3. 78 FR 27471 - Projects Rescinded for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-10

    ... SUSQUEHANNA RIVER BASIN COMMISSION Projects Rescinded for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: This notice lists the approved by rule projects..., being rescinded for the consumptive use of water pursuant to the Commission's approval by rule process...

  4. 78 FR 44923 - Notice of Intent to Seek Approval To Collect Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-25

    ... DEPARTMENT OF AGRICULTURE Agriculture Research Service Notice of Intent to Seek Approval To.... SUMMARY: This notice announces the U.S. Department of Agriculture, Agricultural Research Service, National...: Address all comments concerning this notice to Tara Smith, USDA, Agriculture Research Service, National...

  5. 78 FR 34306 - Approval and Promulgation of Air Quality Implementation Plans: North Carolina; Control Techniques...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-07

    ... Promulgation of Air Quality Implementation Plans: North Carolina; Control Techniques Guidelines and Reasonably Available Control Technology AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY... Carolina's commitment associated with the conditional approval of its reasonably available control...

  6. 78 FR 71619 - Medicare and Medicaid Programs; Continued Approval of American Osteopathic Association/Healthcare...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-29

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Medicare & Medicaid Services [CMS-3285-FN] Medicare and Medicaid Programs; Continued Approval of American Osteopathic Association/Healthcare... Medicare & Medicaid Services, HHS. ACTION: Final notice. SUMMARY: This final notice announces our decision...

  7. 76 FR 25334 - Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Maryland

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-04

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9301-4] Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Maryland AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY..., [email protected] . SUPPLEMENTARY INFORMATION: On October 13, 2005, the final Cross-Media Electronic...

  8. 76 FR 76971 - Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Arkansas

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-09

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9504-4] Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Arkansas AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY..., [email protected] . SUPPLEMENTARY INFORMATION: On October 13, 2005, the final Cross-Media Electronic...

  9. 77 FR 37039 - Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Delaware

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-20

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9690-6] Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Delaware AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY... INFORMATION: On October 13, 2005, the final Cross-Media Electronic Reporting Regulation (CROMERR) was...

  10. 76 FR 76970 - Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Montana

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-09

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9504-3] Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Montana AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY..., [email protected] . SUPPLEMENTARY INFORMATION: On October 13, 2005, the final Cross-Media Electronic...

  11. 76 FR 15975 - Cross-Media Electronic Reporting Regulation Authorized Program Revision/Modification Approvals...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-22

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9284-9] Cross-Media Electronic Reporting Regulation... (EPA). ACTION: Notice. SUMMARY: This notice announces EPA's approval, under regulations for Cross-Media..., [email protected] . SUPPLEMENTARY INFORMATION: On October 13, 2005, the final Cross-Media Electronic...

  12. 76 FR 76971 - Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Indiana

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-09

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9504-5] Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Indiana AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY..., [email protected] . SUPPLEMENTARY INFORMATION: On October 13, 2005, the final Cross-Media Electronic...

  13. 78 FR 35030 - Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Nevada

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-11

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9823-4] Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Nevada AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY..., [email protected] . SUPPLEMENTARY INFORMATION: On October 13, 2005, the final Cross-Media Electronic...

  14. 77 FR 42002 - Revision of Approved Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-17

    ... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLWO3200000-L19900000.PP0000] Revision of Approved Information Collection AGENCY: Bureau of Land Management, Interior. ACTION: 30-day notice and request for comments. SUMMARY: The Bureau of Land Management (BLM) has submitted an information collection...

  15. Drugs Approved for Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for ovarian cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.

  16. 76 FR 59483 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-26

    ... the decision may be purchased by contacting the Office of Public Assistance, Governmental Affairs, and...)] Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board, DOT. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the fourth quarter 2011 Rail Cost Adjustment...

  17. 77 FR 76169 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-26

    ....stb.dot.gov . Copies of the decision may be purchased by contacting the Office of Public Assistance...)] Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board, DOT. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the AAR's proposed rebasing calculations and...

  18. Drugs Approved for Multiple Myeloma

    Cancer.gov

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for multiple myeloma and other plasma cell neoplasms. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.

  19. 77 FR 12837 - Information Collection Being Submitted to OMB for Review and Approval

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-02

    ... FEDERAL COMMUNICATIONS COMMISSION Information Collection Being Submitted to OMB for Review and Approval AGENCY: Federal Communications Commission. ACTION: Notice and request for comments. SUMMARY: The Federal Communications Commission (FCC), as part of its continuing effort to reduce paperwork burdens...

  20. 77 FR 19050 - Actions Taken at December 15, 2011, Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-29

    ... SUSQUEHANNA RIVER BASIN COMMISSION Actions Taken at December 15, 2011, Meeting AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: As part of its regular business meeting held on... took the following actions: (1) Rescinded approval for three water resources projects; and (2) approved...

  1. 76 FR 62142 - Actions Taken at September 15, 2011, Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-06

    ... SUSQUEHANNA RIVER BASIN COMMISSION Actions Taken at September 15, 2011, Meeting AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: As part of its regular business meeting held on... following actions: (1) Approved settlements involving two water resources projects; (2) approved or tabled...

  2. 75 FR 70067 - Notice of Request for Reinstatement of Previously Approved Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-16

    ... address for which the public should request further information related to the relevant Information... Request for Reinstatement of Previously Approved Information Collection ACTION: Notice; Correction SUMMARY... INFORMATION CONTACT: Robert C. Ashby, Office of the Secretary, Office of Assistant General Counsel for...

  3. 77 FR 4616 - Approval of Noise Compatibility Program for Kona International Airport at Keahole, Keahole, North...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-30

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Approval of Noise Compatibility Program for Kona International Airport at Keahole, Keahole, North Kona, HI AGENCY: Federal Aviation Administration, DOT. ACTION: Notice. SUMMARY: The Federal Aviation Administration (FM) announces its findings on...

  4. 77 FR 5183 - Review and Approval of Existing Ordinances or Resolutions; Repeal

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-02

    ... DEPARTMENT OF THE INTERIOR National Indian Gaming Commission 25 CFR Part 523 RIN 3141-AA45 Review and Approval of Existing Ordinances or Resolutions; Repeal AGENCY: National Indian Gaming Commission. ACTION: Final rule. SUMMARY: The National Indian Gaming Commission is repealing obsolete regulations...

  5. 78 FR 69664 - Proposed Information Collection Request; Comment Request; Approval of State Coastal Nonpoint...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-20

    ... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OW-2006-0394; FRL-9903-09-OW] Proposed Information Collection Request; Comment Request; Approval of State Coastal Nonpoint Pollution Control Programs AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: The Environmental Protection Agency is planning...

  6. 76 FR 22411 - Notice of Proposed Information Collection: Comment Request; Housing Counseling Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-21

    ... Information Collection: Comment Request; Housing Counseling Program--Application for Approval as a Housing Counseling Agency AGENCY: Office of the Assistant Secretary for Housing, HUD. ACTION: Notice. SUMMARY: The...: Title of Proposal: Housing Counseling Program--Application for Approval as a Housing Counseling Agency...

  7. 76 FR 63236 - Review and Approval of Existing Ordinances or Resolutions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-12

    ... DEPARTMENT OF THE INTERIOR National Indian Gaming Commission 25 CFR Part 523 RIN 3141-AA45 Review and Approval of Existing Ordinances or Resolutions AGENCY: National Indian Gaming Commission, Interior. ACTION: Notice of proposed rulemaking. SUMMARY: On November 18, 2010, the National Indian Gaming...

  8. 77 FR 63799 - Proposed Extension of Approval of Information Collection; Comment Request-Children's Sleepwear

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-17

    ... CONSUMER PRODUCT SAFETY COMMISSION Proposed Extension of Approval of Information Collection; Comment Request--Children's Sleepwear AGENCY: Consumer Product Safety Commission. ACTION: Notice; correction. SUMMARY: As required by the Paperwork Reduction Act of 1995 (44 U.S.C. Chapter 35), the Consumer...

  9. 77 FR 68770 - Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Vermont

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-16

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL9752-3] Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Vermont AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY... 13, 2005, the final Cross-Media Electronic Reporting Rule (CROMERR) was published in the Federal...

  10. 76 FR 30342 - Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Ohio

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-25

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9311-3] Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Ohio AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY... 13, 2005, the final Cross-Media Electronic Reporting Rule (CROMERR) was published in the Federal...

  11. 77 FR 13123 - Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Ohio

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-05

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9642-8] Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Ohio AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY... . SUPPLEMENTARY INFORMATION: On October 13, 2005, the final Cross-Media Electronic Reporting Rule (CROMERR) was...

  12. 75 FR 65627 - Cross-Media Electronic Reporting Rule State Authorized Program Revision Approval: State of Arkansas

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-26

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9217-6] Cross-Media Electronic Reporting Rule State...: Notice. SUMMARY: This notice announces EPA's approval, under regulations for Cross-Media Electronic..., NW., Washington, DC 20460. SUPPLEMENTARY INFORMATION: On October 13, 2005, the final Cross-Media...

  13. 77 FR 71792 - Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Georgia

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-04

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9757-6] Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Georgia AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY...-Media Electronic Reporting Rule (CROMERR) was published in the Federal Register (70 FR 59848) and...

  14. 77 FR 37038 - Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Illinois

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-20

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9690-5] Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Illinois AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY... . SUPPLEMENTARY INFORMATION: On October 13, 2005, the final Cross-Media Electronic Reporting Rule (CROMERR) was...

  15. 76 FR 24020 - Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Illinois

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-29

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9293-7] Cross-Media Electronic Reporting: Authorized Program Revision Approval, State of Illinois AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY... final Cross-Media Electronic Reporting Rule (CROMERR) was published in the Federal Register (70 FR 59848...

  16. 75 FR 69660 - Cross-Media Electronic Reporting Rule State Authorized Program Revision Approval: State of Hawaii

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-15

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9226-9] Cross-Media Electronic Reporting Rule State...: Notice. SUMMARY: This notice announces EPA's approval, under regulations for Cross-Media Electronic..., NW., Washington, DC 20460. SUPPLEMENTARY INFORMATION: On October 13, 2005, the final Cross-Media...

  17. 42 CFR 422.157 - Accreditation organizations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., on an annual basis, summary data specified by CMS that relate to the past year's accreditation... respect to the standard or standards in question. (2) It complies with the application and reapplication... term of the approval, which may not exceed 6 years. (c) Ongoing responsibilities of an approved...

  18. 76 FR 12761 - Notice of Intent To Seek Approval To Continue an Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-08

    ... social and behavioral sciences. 2. Achievements of an unusually significant nature in relation to the... NATIONAL SCIENCE FOUNDATION Notice of Intent To Seek Approval To Continue an Information Collection AGENCY: National Science Foundation. ACTION: Notice and Request for Comments. SUMMARY: The...

  19. Connected Vehicle Pilot Deployment Program Phase 1 : Human Use Approval Summary : New York City

    DOT National Transportation Integrated Search

    2016-08-04

    The New York City (NYC) Connected Vehicle (CV) Pilot Deployment will be the largest deployment of connected vehicle technology to date. The purpose of the human use approval activity is to apply the Institutional Review Board (IRB) process to the NYC...

  20. 77 FR 37958 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-25

    ..., http://www.stb.dot.gov . Copies of the decision may be purchased by contacting the Office of Public...)] Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board, DOT. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the third quarter 2012 rail cost adjustment...

  1. 75 FR 35877 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-23

    ... available on our Web site, http://www.stb.dot.gov . Copies of the decision may be purchased by contacting...-3)] Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the third quarter 2010 rail cost...

  2. 75 FR 58019 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-23

    ..., http://www.stb.dot.gov . Copies of the decision may be purchased by contacting the office of Public...)] Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board, DOT. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the fourth quarter 2010 Rail Cost Adjustment...

  3. 75 FR 80895 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-23

    ..., http://www.stb.dot.gov . Copies of the decision may be purchased by contacting the Office of Public...)] Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board, DOT. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the first quarter 2011 Rail Cost Adjustment...

  4. 76 FR 16037 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-22

    ..., http://www.stb.dot.gov . Copies of the decision may be purchased by contacting the Office of Public...)] Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board, DOT. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the second quarter 2011 Rail Cost Adjustment...

  5. 78 FR 37660 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-21

    ..., http://www.stb.dot.gov . Copies of the decision may be purchased by contacting the Office of Public...)] Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board, DOT. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board approves the third quarter 2013 Rail Cost Adjustment Factor...

  6. 76 FR 37191 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-24

    ... our Web site, http://www.stb.dot.gov . Copies of the decision may be purchased by contacting the...)] Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board, DOT. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the third quarter 2011 Rail Cost Adjustment...

  7. 78 FR 59093 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-25

    ...)] Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board, DOT ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the fourth quarter 2013 rail cost adjustment factor (RCAF) and cost index filed by the Association of American Railroads. The fourth quarter 2013 RCAF...

  8. 78 FR 17764 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-22

    ..., http://www.stb.dot.gov . Copies of the decision may be purchased by contacting the Office of Public...)] Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board, DOT. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the second quarter 2013 Rail Cost Adjustment...

  9. 77 FR 37062 - Intent To Request Approval From OMB of One New Public Collection of Information: Office of Law...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-20

    ... DEPARTMENT OF HOMELAND SECURITY Transportation Security Administration Intent To Request Approval... Service LEO Reimbursement Request AGENCY: Transportation Security Administration, DHS. ACTION: 60-day Notice. SUMMARY: The Transportation Security Administration (TSA) invites public comment on a new...

  10. 78 FR 16200 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-14

    ...-0240; Directorate Identifier 2011-SW-060-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for certain Eurocopter France (Eurocopter... helicopters have been approved by the aviation authority of France and are approved for operation in the...

  11. 77 FR 36216 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-18

    ...-0631; Directorate Identifier 2011-SW-021-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France... rulemaking (NPRM). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France... approved by the aviation authority of France and are approved for operation in the United States. Pursuant...

  12. 78 FR 37154 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-20

    ...-0523; Directorate Identifier 2012-SW-091-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... Determination These helicopters have been approved by the aviation authority of France and are approved for...

  13. 78 FR 34960 - Airworthiness Directives; Eurocopter France Model Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-11

    ...-0501; Directorate Identifier 2011-SW-036-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France... rulemaking (NPRM). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France... Determination These helicopters have been approved by the aviation authority of France and are approved for...

  14. 78 FR 51115 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-20

    ...-0737; Directorate Identifier 2012-SW-111-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for certain Eurocopter France (Eurocopter... approved by the aviation authority of France and are approved for operation in the United States. Pursuant...

  15. 77 FR 56234 - Notice of Intent To Seek Approval To Establish an Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-12

    ... NATIONAL SCIENCE FOUNDATION Notice of Intent To Seek Approval To Establish an Information Collection AGENCY: National Science Foundation. ACTION: Notice and request for comments. SUMMARY: The National Science Foundation (NSF) is announcing plans to request clearance of this collection. In...

  16. 77 FR 56235 - Notice of Intent To Seek Approval To Establish an Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-12

    ... NATIONAL SCIENCE FOUNDATION Notice of Intent To Seek Approval To Establish an Information Collection AGENCY: National Science Foundation. ACTION: Notice and request for comments. SUMMARY: The National Science Foundation (NSF) is announcing plans to request clearance of this collection. In...

  17. 76 FR 60774 - Review and Approval of Projects

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-30

    ... SUSQUEHANNA RIVER BASIN COMMISSION 18 CFR Part 806 Review and Approval of Projects AGENCY: Susquehanna River Basin Commission. ACTION: Notice of proposed rulemaking; reopening of comment period. SUMMARY: The purpose of this document is to inform the public of an extension of the comment period for...

  18. 76 FR 32378 - Notice of Intent To Seek Approval To Establish an Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-06

    ... opportunity for public comment on proposed data collection projects, the National Science Foundation (NSF... NATIONAL SCIENCE FOUNDATION Notice of Intent To Seek Approval To Establish an Information Collection AGENCY: National Science Foundation. ACTION: Notice and Request for Comments. SUMMARY: In...

  19. 76 FR 28242 - Proposed Extension of the Approval of Information Collection Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-16

    ... DEPARTMENT OF LABOR Wage and Hour Division Proposed Extension of the Approval of Information Collection Requirements AGENCY: Wage and Hour Division, Department of Labor. ACTION: Notice. SUMMARY: The... be properly assessed. Currently, the Wage and Hour Division is soliciting comments concerning its...

  20. 76 FR 41855 - Actions Taken at June 23, 2011, Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-15

    ... SUSQUEHANNA RIVER BASIN COMMISSION Actions Taken at June 23, 2011, Meeting AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: As part of its regular business meeting held on June 23... actions: (1) Approved settlement involving one water resources project; (2) approved and tabled the...

  1. 7 CFR 1942.5 - Application review and approval.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Public Law 103-354 by written amendment to this letter. Any changes not approved by FmHA or its successor... Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS... complete the project summary, including written analysis and recommendations, and will prepare a draft...

  2. 77 FR 13151 - Agency Information Collection Activities: Proposed Collection; Comments Requested; Records and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-05

    ... Data: Daily Summaries, Records of Production, Storage, and Disposition, and Supporting Data by Licensed... approved collection. (2) Title of the Form/Collection: Records and Supporting Data: Daily Summaries, Records of Production, Storage and Disposition and Supporting Data by Explosives Manufacturers. (3) Agency...

  3. 78 FR 48638 - Approval and Promulgation of State Implementation Plans: Alaska; Fairbanks Carbon Monoxide...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-09

    ... Promulgation of State Implementation Plans: Alaska; Fairbanks Carbon Monoxide Limited Maintenance Plan AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: The EPA is proposing to approve a carbon... carbon monoxide National Ambient Air Quality Standards through the second 10- year maintenance period...

  4. 78 FR 73522 - Agency Information Collection Activities: Submission to OMB for Review and Approval; State Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-06

    ... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OECA-2010-0291; FRL- 9903-87-OEI] Agency Information Collection Activities: Submission to OMB for Review and Approval; State Review Framework; EPA ICR Number 2185.05 AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: In compliance with the...

  5. 77 FR 19525 - National School Lunch Program: School Food Service Account Revenue Amendments Related to the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-02

    ... National School Lunch Program: School Food Service Account Revenue Amendments Related to the Healthy, Hunger-Free Kids Act of 2010; Approval of Information Collection Request AGENCY: Food and Nutrition Service, USDA. ACTION: Interim final rule; approval of information collection request. SUMMARY: The Food...

  6. 77 FR 52277 - Approval of Air Quality Implementation Plans; California; South Coast Air Quality Management...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-29

    ... Quality Implementation Plans; California; South Coast Air Quality Management District; Prevention of... rule. SUMMARY: EPA is proposing approval of a permitting rule submitted for the South Coast Air Quality Management District (District) portion of the California State Implementation Plan (SIP). The State is...

  7. 7 CFR 1710.206 - Approval requirements for load forecasts prepared pursuant to approved load forecast work plans.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... effects on electric revenues caused by competition from alternative energy sources or other electric... uncertainty or alternative futures that may determine the borrower's actual loads. Examples of economic... basis. Include alternative futures, as applicable. This summary shall be designed to accommodate the...

  8. 7 CFR 1710.206 - Approval requirements for load forecasts prepared pursuant to approved load forecast work plans.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... effects on electric revenues caused by competition from alternative energy sources or other electric... uncertainty or alternative futures that may determine the borrower's actual loads. Examples of economic... basis. Include alternative futures, as applicable. This summary shall be designed to accommodate the...

  9. 7 CFR 1710.206 - Approval requirements for load forecasts prepared pursuant to approved load forecast work plans.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... effects on electric revenues caused by competition from alternative energy sources or other electric... uncertainty or alternative futures that may determine the borrower's actual loads. Examples of economic... basis. Include alternative futures, as applicable. This summary shall be designed to accommodate the...

  10. 7 CFR 1710.206 - Approval requirements for load forecasts prepared pursuant to approved load forecast work plans.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... effects on electric revenues caused by competition from alternative energy sources or other electric... uncertainty or alternative futures that may determine the borrower's actual loads. Examples of economic... basis. Include alternative futures, as applicable. This summary shall be designed to accommodate the...

  11. 75 FR 2535 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-15

    ... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OW-2006-0394; FRL-9103-7; EPA ICR No. 1569.07; OMB Control...; Comment Request; Approval of State Coastal Nonpoint Pollution Control Programs (Renewal) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: In compliance with the Paperwork Reduction Act...

  12. 76 FR 24061 - Notice of Intent To Seek Approval To Extend a Current Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-29

    ... NATIONAL SCIENCE FOUNDATION Notice of Intent To Seek Approval To Extend a Current Information Collection AGENCY: National Science Foundation. ACTION: Notice and request for comments. SUMMARY: The National Science Foundation (NSF) is announcing plans to request renewal of this collection. In accordance...

  13. 77 FR 66543 - Approval and Promulgation of Air Quality Implementation Plans; Delaware; Requirements for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-06

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R03-OAR-2012-0381; FRL-9747-9] Approval and Promulgation of Air Quality Implementation Plans; Delaware; Requirements for Prevention of Significant...: Environmental Protection Agency (EPA). ACTION: Final rule; correcting amendment. SUMMARY: This document corrects...

  14. 77 FR 41916 - Approval and Promulgation of Implementation Plans; Idaho: Infrastructure Requirements for the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-17

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R10-OAR-2011-0724, FRL-9676-6] Approval and... Ambient Air Quality Standard; Prevention of Significant Deterioration Greenhouse Gas Permitting Authority and Tailoring Rule AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY: EPA is...

  15. 77 FR 65625 - Approval and Promulgation of Air Quality Implementation Plans; New Hampshire; Determination of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-30

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 Approval and Promulgation of Air Quality... Portsmouth-Dover-Rochester and Manchester Areas AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY: The EPA is making four separate and independent air quality determinations for two areas...

  16. 75 FR 1617 - Cross-Media Electronic Reporting Rule State Authorized Program Revision Approval: State of New York

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-12

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9102-4] Cross-Media Electronic Reporting Rule State...: Notice. SUMMARY: This notice announces EPA's approval, under regulations for Cross-Media Electronic... October 13, 2005, the final Cross-Media Electronic Reporting Rule (CROMERR) was published in the Federal...

  17. 75 FR 3463 - Cross-Media Electronic Reporting Rule State Authorized Program Revision Approval: State of North...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9104-9] Cross-Media Electronic Reporting Rule State...). ACTION: Notice. SUMMARY: This notice announces EPA's approval, under regulations for Cross-Media... INFORMATION: On October 13, 2005, the final Cross-Media Electronic Reporting Rule (CROMERR) was published in...

  18. 78 FR 26618 - Collection of Information; Proposed Extension of Approval; Comment Request-Follow-Up Activities...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-07

    ... CONSUMER PRODUCT SAFETY COMMISSION [Docket No. CPSC-2009-0102] Collection of Information; Proposed Extension of Approval; Comment Request--Follow-Up Activities for Product-Related Injuries AGENCY: Consumer Product Safety Commission. ACTION: Notice. SUMMARY: As required by the Paperwork Reduction Act of 1995...

  19. 78 FR 73523 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request; NSPS...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-06

    ... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OECA-2013-0310; FRL-9903-74-OEI] Information Collection... (Renewal) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: The Environmental... Office of Management and Budget (OMB) for review and approval in accordance with the Paperwork Reduction...

  20. 76 FR 508 - Approval and Promulgation of Implementation Plans; Idaho

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-05

    ... Promulgation of Implementation Plans; Idaho AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is proposing to approve revisions to the Idaho State Implementation Plan (SIP) that were submitted to EPA by the State of Idaho on April 16, 2007. This SIP submittal includes new and...

  1. 78 FR 53386 - Approval and Promulgation of Implementation Plans; State of Missouri; St. Louis Area...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-29

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R07-OAR-2013-0482; FRL 9900-40-Region 7] Approval and Promulgation of Implementation Plans; State of Missouri; St. Louis Area Transportation Conformity Requirements AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is...

  2. 76 FR 17136 - Medical Devices; Availability of Safety and Effectiveness Summaries for Premarket Approval...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-28

    ... section 515(d)(4) and (e)(2) of the Federal Food, Drug, and Cosmetic Act (the FD&C Act) (21 U.S.C. 360e(d......... Dako Denmark A/S..... HercepTest kit Approved October 20, 2010. P080009 Ethicon Endo-Surgery, SEDASYS...

  3. 77 FR 70689 - Approval and Promulgation of Implementation Plans; Tennessee; Regional Haze State Implementation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-27

    ... Retrofit Technology Requirements for Eastman Chemical Company AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY: EPA is finalizing approval of the Best Available Retrofit Technology (BART... retrofitting its facility pursuant to the BART determination for SO 2 emissions (hereafter referred to as the...

  4. 78 FR 37813 - Information Collection Being Submitted for Review and Approval to the Office of Management and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-24

    ... FEDERAL COMMUNICATIONS COMMISSION Information Collection Being Submitted for Review and Approval to the Office of Management and Budget AGENCY: Federal Communications Commission. ACTION: Notice and request for comments. SUMMARY: The Federal Communications Commission (FCC), as part of its continuing...

  5. 77 FR 66432 - Request for Extension and Revision of a Currently Approved Information Collection for the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-05

    ... DEPARTMENT OF AGRICULTURE Agricultural Marketing Service [Doc. Nos. AMS-TM-12-0050; TM-12-02... Market Questionnaire AGENCY: Agricultural Marketing Service, USDA. ACTION: Request for comments. SUMMARY... announces the Agricultural Marketing Service's (AMS) intention to request approval, from the Office of...

  6. 76 FR 80448 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-23

    ...)] Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the first quarter 2012 rail cost adjustment factor (RCAF... decision, which is available on our Web site, http://www.stb.dot.gov . Copies of the decision may be...

  7. 77 FR 58910 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-24

    ..., http://www.stb.dot.gov . Copies of the decision may be purchased by contacting the Office of Public...)] Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the fourth quarter 2012 rail cost adjustment factor (RCAF...

  8. 75 FR 62817 - Notice of Public Information Collection(s) Being Submitted to OMB for Review and Approval

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-13

    ... FEDERAL COMMUNICATIONS COMMISSION Notice of Public Information Collection(s) Being Submitted to OMB for Review and Approval September 30, 2010. SUMMARY: The Federal Communications Commission, as... automated collection techniques or other forms of information technology. DATES: Written comments should be...

  9. 78 FR 25697 - Notice of Intent To Seek OMB Approval To Collect Information: On-Line Architectural Barriers Act...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-02

    ... ARCHITECTURAL AND TRANSPORTATION BARRIERS COMPLIANCE BOARD Notice of Intent To Seek OMB Approval...: Architectural and Transportation Barriers Compliance Board. ACTION: 30-day Notice and request for comments. SUMMARY: The Architectural and Transportation Barriers Compliance Board (Access Board) has requested...

  10. 77 FR 74826 - Notice of Intent To Seek OMB Approval To Collect Information: On-Line Architectural Barriers Act...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-18

    ... ARCHITECTURAL AND TRANSPORTATION BARRIERS COMPLIANCE BOARD Notice of Intent To Seek OMB Approval...: Architectural and Transportation Barriers Compliance Board. ACTION: Notice and request for comments. SUMMARY: The Architectural and Transportation Barriers Compliance Board (Access Board) plans to request...

  11. 76 FR 28414 - Notice of Request for Approval of an Information Collection; National Animal Health Monitoring...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ...] Notice of Request for Approval of an Information Collection; National Animal Health Monitoring System... information collection; comment request. SUMMARY: In accordance with the Paperwork Reduction Act of 1995, this... Epidemiologic Investigations, an information collection to support the National Animal Health Monitoring System...

  12. 75 FR 64357 - Notice of Intent To Seek Approval To Renew an Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-19

    ... NATIONAL SCIENCE FOUNDATION Notice of Intent To Seek Approval To Renew an Information Collection AGENCY: National Science Foundation. ACTION: Notice and request for comments. SUMMARY: The National Science Foundation (NSF) is announcing plans to request clearance of this collection. In accordance with...

  13. 77 FR 11787 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-28

    ...-0177; Directorate Identifier 2009-SW-59-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France Model EC155B and... approved by the aviation authority of France and are approved for operation in the United States. Pursuant...

  14. 77 FR 14310 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-09

    ...-0222; Directorate Identifier 2011-SW-007-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for certain Eurocopter France Model AS350... Determination These products have been approved by the aviation authority of France and are approved for...

  15. 75 FR 43066 - Approval and Promulgation of Implementation Plans; New York Reasonably Available Control...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-23

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R02-OAR-2009-0462, FRL-9178-5] Approval and Promulgation of Implementation Plans; New York Reasonably Available Control Technology and Reasonably Available Control Measures AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY: EPA is...

  16. 78 FR 78726 - Approval and Promulgation of Air Quality Implementation Plans; Indiana; Volatile Organic Compound...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-27

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R05-OAR-2012-0453; FRL-9904-35-Region 5... Control Measures for Industrial Solvent Cleaning for Northwest Indiana AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY: The Environmental Protection Agency (EPA) is approving a...

  17. 75 FR 82363 - Approval and Promulgation of Implementation Plans; Ohio; Volatile Organic Compound Emission...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-30

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R05-OAR-2010-0259; FRL-9245-8] Approval and... Lithographic and Letterpress Printing in Cleveland AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: On March 9, 2010, the Ohio Environmental Protection Agency (Ohio EPA) submitted...

  18. 77 FR 43000 - Approval and Promulgation of Air Quality Implementation Plans; Maryland; Offset Lithographic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-23

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R03-OAR-2012-0042; FRL-9702-2] Approval and... Printing Regulations AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY: EPA is... Technology (RACT) for sources covered by EPA's Control Techniques Guidelines (CTG) for offset lithographic...

  19. 76 FR 23326 - Intent To Request Renewal From OMB of One Current Public Collection of Information...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-26

    ... DEPARTMENT OF HOMELAND SECURITY Transportation Security Administration [Docket No. TSA-2006-24191... Notice. SUMMARY: The Transportation Security Administration (TSA) invites public comment on one currently... approved the collection of information for six months and TSA now seeks the maximum three-year approval...

  20. 77 FR 2071 - Medical Devices; Availability of Safety and Effectiveness Summaries for Premarket Approval...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-13

    .... Docket No. Applicant Trade name Approval date P100031, FDA-2011-M-0502...... Roche Diagnostics ELECSYS......... Roche Diagnostics ELECSYS ANTI-HBC IMMUNOASSAY, June 27, 2011. Corp.. ELECSYS PRECICONTROL ANTI-HBC FOR... IMMUNODIAGNOSTICS July 20, 2011. Diagnostics, PRODUCTS ANTI-HBE REAGENT PACK, Inc.. VITROS IMMUNODIAGNOSTIC PRODUCTS...

  1. 76 FR 4917 - Agency Information Collection Activities; Announcement of Office of Management and Budget...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-27

    ... of Tobacco Communications'' has been approved by the Office of Management and Budget (OMB) under the...] Agency Information Collection Activities; Announcement of Office of Management and Budget Approval; Pretesting of Tobacco Communications AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The...

  2. 77 FR 60442 - Withdrawal of Approval of New Animal Drug Applications; Butorphanol; Doxapram; Triamcinolone...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-03

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-N-0981] Withdrawal of Approval of New Animal Drug Applications; Butorphanol; Doxapram; Triamcinolone; Tylosin AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is...

  3. 77 FR 27772 - Information Collections Being Submitted for Review and Approval to the Office of Management and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-11

    ... FEDERAL COMMUNICATIONS COMMISSION Information Collections Being Submitted for Review and Approval to the Office of Management and Budget AGENCY: Federal Communications Commission. ACTION: Notice and request for comments. SUMMARY: The Federal Communications Commission (FCC), as part of its continuing...

  4. 77 FR 31634 - Approval of Inspectorate America Corporation, as a Commercial Gauger

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-29

    ... America Corporation, as a Commercial Gauger AGENCY: U.S. Customs and Border Protection, Department of Homeland Security. ACTION: Notice of approval of Inspectorate America Corporation, as a commercial gauger. SUMMARY: Notice is hereby given that, pursuant to 19 CFR 151.13, Inspectorate America Corporation, 125...

  5. 77 FR 60686 - Proposed Extension of Approval of Information Collection; Comment Request-Safety Standard for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-04

    ... CONSUMER PRODUCT SAFETY COMMISSION [Docket No. CPSC-2013-0001] Proposed Extension of Approval of... AGENCY: Consumer Product Safety Commission. ACTION: Notice. SUMMARY: As required by the Paperwork Reduction Act (44 U.S.C. chapter 35), the Consumer Product Safety Commission (CPSC or Commission) requests...

  6. 78 FR 26611 - Notice of Intent To Seek Approval To Conduct an Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-07

    ... Statistics Service Notice of Intent To Seek Approval To Conduct an Information Collection AGENCY: National Agricultural Statistics Service, USDA. ACTION: Notice and request for comments. SUMMARY: In accordance with the Paperwork Reduction Act of 1995, this notice announces the intention of the National Agricultural Statistics...

  7. USACE AIS Transmit Technical Support Summary Report

    DTIC Science & Technology

    2014-09-01

    the TAG block for the correct transmitters, and then send to the USACE AIS network. B. Outbound openings in the USCG firewall for the USCG Message...USACE AIS Transmit Technical Support Summary Report Distribution Statement A: Approved for public release; distribution is unlimited...September 2014 Report No. CD-D-09-15 USACE AIS Transmit Technical Support Summary Report ii UNCLAS//Public | CG-926 RDC | I. Gonin et al. Public

  8. Neurostimulation for Drug-Resistant Epilepsy

    PubMed Central

    DeGiorgio, Christopher M.; Krahl, Scott E.

    2013-01-01

    Purpose of Review: The purpose of this review is to provide an evidence-based update on the neurostimulation options available for patients with drug-resistant epilepsy in the United States and in European countries. Recent Findings: The field of neurostimulation for epilepsy has grown dramatically since 1997, when vagus nerve stimulation became the first device to be approved for epilepsy by the US Food and Drug Administration (FDA). New data from recently completed randomized controlled trials are available for deep brain stimulation of the anterior thalamus, responsive neurostimulation, and trigeminal nerve stimulation. Although vagus nerve stimulation is the only device currently approved in the United States, deep brain stimulation and responsive neurostimulation devices are awaiting FDA approval. Deep brain stimulation, trigeminal nerve stimulation, and transcutaneous vagus nerve stimulation are now approved for epilepsy in the European Union. In this article, the mechanisms of action, safety, and efficacy of new neurostimulation devices are reviewed, and the key advantages and disadvantages of each are discussed. Summary: The exponential growth of the field of neuromodulation for epilepsy is an exciting development; these new devices provide physicians with new options for patients with drug-resistant epilepsy. PMID:23739108

  9. 77 FR 16795 - Approval and Promulgation of Implementation Plans and Operating Permits Program; Commonwealth of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-22

    .... SUMMARY: EPA is proposing to approve revisions to the Puerto Rico Regulations for the Control of Atmospheric Pollution, submitted to EPA by the Puerto Rico Environmental Quality Board (PREQB) on July 13... de Leon Avenue, Stop 22, Santurce, Puerto Rico 00909. FOR FURTHER INFORMATION CONTACT: Kirk J. Wieber...

  10. 76 FR 66964 - Notice of Proposed Information Collection for 1029-0036

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-28

    ... Requirements for Reclamation and Operation Plan. This information collection activity was previously approved... Requirements for Reclamation and Operation Plan. OSM will request a 3-year term of approval for this... Reclamation and Operation Plan. OMB Control Number: 1029-0036. Summary: Sections 507(b), 508(a), 510(b), 515(b...

  11. 78 FR 33784 - Approval and Promulgation of Implementation Plans; Kentucky: Kentucky Portion of Cincinnati...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-05

    ... Promulgation of Implementation Plans; Kentucky: Kentucky Portion of Cincinnati-Hamilton, Supplement Motor.... SUMMARY: EPA is proposing to approve a revision to the Kentucky State Implementation Plan (SIP), submitted... maintenance plan for the Kentucky portion of the Cincinnati-Hamilton, OH-KY-IN, maintenance area for the 1997...

  12. 77 FR 38033 - Notice of Establishment of a Commodity Import Approval Process Web Site

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-26

    ... Process Web Site AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION: Notice. SUMMARY: We are announcing the creation of a new Plant Protection and Quarantine Web site that will provide stakeholders with... comment on draft risk assessments. This Web site will make the commodity import approval process more...

  13. 76 FR 48181 - Proposed Extension of the Approval of Information Collection Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-08

    ... employee during the prior week.'' This requirement is implemented by 29 CFR 3.3 and 3.4 and the standard... DEPARTMENT OF LABOR Wage and Hour Division Proposed Extension of the Approval of Information Collection Requirements AGENCY: Wage and Hour Division, Department of Labor. ACTION: Notice. SUMMARY: The...

  14. 77 FR 33392 - Notice of Intent to Request an Extension of a Currently Approved Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-06

    ... DEPARTMENT OF AGRICULTURE National Institute of Food and Agriculture Notice of Intent to Request... Agriculture, USDA ACTION: Notice and request for comments. SUMMARY: In accordance with the Office of... announces the National Institute of Food and Agriculture's (NIFA) intention to request approval for an...

  15. 75 FR 52001 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-24

    ... Activities; Submission to OMB for Review and Approval; Comment Request; Minority Business Enterprise/ Woman... Agency (EPA). ACTION: Notice. SUMMARY: In compliance with the Paperwork Reduction Act (PRA) (44 U.S.C... Pennsylvania Ave., NW., Washington, DC 20460, and (2) OMB by mail to: Office of Information and Regulatory...

  16. 78 FR 79317 - Approval of Request for Delegation of Authority for Prevention of Accidental Release, North...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-30

    ... Department of Agriculture AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY: The Environmental Protection Agency (EPA) is taking final action to approve North Dakota Department of Agriculture's... Department of Agriculture (iv) The initials RMP mean Risk Management Plan (v) The initials CFR mean Code of...

  17. 75 FR 73082 - Agency Information Collection Activities: Final Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-29

    ... Review and Comments Request. Form Title: Application for Approved Finance Provider (EIB 10-06). SUMMARY... Approved Finance Provider will be used to determine if the finance provider has the financial strength and... programs. Export- Import Bank potential finance providers will be able to submit this form on paper. In the...

  18. 76 FR 6787 - Agency Information Collection Activities: Final Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-08

    ... Review and Comments Request. Form Title: Application for Approved Finance Provider (EIB 10-06) SUMMARY... Approved Finance Provider will be used to determine if the finance provider has the financial strength and... programs. Export- Import Bank potential finance providers will be able to submit this form on paper. In the...

  19. 78 FR 70496 - Withdrawal of Approval of New Animal Drug Applications; Arsanilic Acid

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-26

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Part 558 [Docket No. FDA-2013-N-0002] Withdrawal of Approval of New Animal Drug Applications; Arsanilic Acid AGENCY: Food and Drug Administration, HHS. ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is...

  20. 76 FR 69318 - Notice of Request for Extension of a Currently Approved Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-08

    ... TRADE AND DEVELOPMENT AGENCY Notice of Request for Extension of a Currently Approved Information Collection AGENCY: United States Trade and Development. ACTION: Request for comments. SUMMARY: In accordance with the Paperwork Reduction Act of 1995 (44 U.S.C. Chapter 35 et seq.), the U.S. Trade and Development...

  1. 78 FR 48611 - Approval and Promulgation of State Implementation Plans: Alaska; Fairbanks Carbon Monoxide...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-09

    ... rule. SUMMARY: The EPA is taking direct final action to approve a carbon monoxide (CO) Limited... maintain the CO National Ambient Air Quality Standards (NAAQS) through the second 10-year maintenance..., Suite 900, Seattle, WA 98101. Hand Delivery/Courier: U.S. EPA Region 10, 1200 Sixth Avenue, Suite 900...

  2. 75 FR 68429 - Cranes and Derricks in Construction; Approval of Information Collection Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-08

    .... OSHA-2007-0066] RIN 1218-AC01 Cranes and Derricks in Construction; Approval of Information Collection... requirements. SUMMARY: On August 9, 2010, OSHA published a final rule revising the Cranes and Derricks Standard... necessary to protect employees during the use of cranes and derricks in construction. That final standard...

  3. 78 FR 77660 - Proposed Extension of Approval of Information Collection; Comment Request-Safety Standards for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-24

    ... CONSUMER PRODUCT SAFETY COMMISSION [Docket No. CPSC-2010-0075] Proposed Extension of Approval of... Cribs AGENCY: Consumer Product Safety Commission. ACTION: Notice. SUMMARY: As required by the Paperwork Reduction Act of 1995 (44 U.S.C. chapter 35), the Consumer Product Safety Commission (CPSC or Commission...

  4. 75 FR 56027 - Approval and Promulgation of Air Quality Implementation Plans; Texas; Revisions to the New Source...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-15

    ... Implementation Plan (SIP); Prevention of Significant Deterioration (PSD) AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is proposing to approve revisions to the Texas PSD State... revision submitted July 16, 2010. This action makes no significant changes to the Texas PSD SIP; it merely...

  5. 76 FR 11779 - Notice of Public Information Collection(s) Approved by the Office of Management and Budget

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-03

    ... FEDERAL COMMUNICATIONS COMMISSION Notice of Public Information Collection(s) Approved by the Office of Management and Budget February 23, 2011. SUMMARY: The Federal Communications Commission has... information contained under OMB control number 3060-1144 is necessary to prepare one of the Commission's media...

  6. 76 FR 50249 - Agency Information Collection Activities: Submitted for Office of Management and Budget (OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-12

    ... currently approved information collection. SUMMARY: To comply with the Paperwork Reduction Act of 1995 (PRA... renew approval of the paperwork requirements in this ICR titled ``30 CFR Part 1220, OCS Net Profit Share... information. SUPPLEMENTARY INFORMATION: Title: 30 CFR Part 1220, OCS Net Profit Share Payment Reporting. OMB...

  7. 78 FR 4337 - Approval and Promulgation of Air Quality Implementation Plans; New Mexico; Infrastructure and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-22

    ... Promulgation of Air Quality Implementation Plans; New Mexico; Infrastructure and Interstate Transport.... SUMMARY: EPA is approving the submittal from the State of New Mexico pursuant to the Clean Air Act (CAA or..., and enforce the 2006 fine particulate matter (PM 2.5 ) national ambient air quality standards (NAAQS...

  8. 75 FR 48894 - Approval and Promulgation of Air Quality Implementation Plans; New Mexico; Revisions to Emissions...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-12

    ... Promulgation of Air Quality Implementation Plans; New Mexico; Revisions to Emissions Inventory Reporting.... SUMMARY: The EPA is proposing to approve revisions to the New Mexico State Implementation Plan (SIP... Quality Standards that EPA has established for criteria pollutants such as ozone, particulate matter, and...

  9. GI Course Approvals.

    ERIC Educational Resources Information Center

    Orlans, Harold; And Others

    The process by which institutions and courses are approved for veterans educational benefits is examined in this study mandated by Public Law 95-202. The legislative background of the investigation is described as well as the history of the Servicemen's Readjustment Act of 1944, the Korean Bill of 1952, and P.L. 94-502 of 1976. A summary guide to…

  10. 76 FR 56701 - Approval and Promulgation of Implementation Plans and Designations of Areas for Air Quality...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-14

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R04-OAR-2010-0604-201140; FRL-9464-1] Approval... AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is proposing to make..., Air, Pesticides and Toxics Management Division, U.S. Environmental Protection Agency, Region 4, 61...

  11. 78 FR 78796 - Supplemental Applications Proposing Labeling Changes for Approved Drugs and Biological Products...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-27

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Parts 314 and 601... Approved Drugs and Biological Products; Correction and Extension of Comment Period AGENCY: Food and Drug Administration, HHS. ACTION: Proposed rule; correction and extension of comment period. SUMMARY: The Food and...

  12. 75 FR 23167 - Approval and Promulgation of Implementation Plans; New Mexico; Interstate Transport of Pollution

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-03

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R06-OAR-2007-0993; FRL-9144-4] Approval and Promulgation of Implementation Plans; New Mexico; Interstate Transport of Pollution AGENCY: Environmental Protection Agency (EPA). ACTION: Withdrawal of direct final rule. SUMMARY: On April 8, 2010 (75 FR 17868...

  13. 78 FR 63429 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-24

    ...-0872; Directorate Identifier 2013-SW-012-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France Model AS332C, AS332L... approved by the aviation authority of France and are approved for operation in the United States. Pursuant...

  14. 76 FR 66682 - Request for an Extension to a Currently Approved Information Collection for the Regulations...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-27

    ... Marketing Service's (AMS) intention to request approval from the Office of Management and Budget, for an... DEPARTMENT OF AGRICULTURE Agricultural Marketing Service [Doc. No.: AMS-DA-11-0087; DA-11-05] RIN...) AGENCY: Agricultural Marketing Service, USDA. ACTION: Request for comments. SUMMARY: In accordance with...

  15. 78 FR 23884 - Seed Testing Service Program; Request for an Extension of and Revision to a Currently Approved...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-23

    ... Marketing Service's (AMS) intention to request approval from the Office of Management and Budget (OMB), for... DEPARTMENT OF AGRICULTURE Agricultural Marketing Service [Doc. No. AMS-LS-13-0007] Seed Testing... AGENCY: Agricultural Marketing Service, USDA. ACTION: Request for comments. SUMMARY: In accordance with...

  16. Space physics missions handbook

    NASA Technical Reports Server (NTRS)

    Cooper, Robert A. (Compiler); Burks, David H. (Compiler); Hayne, Julie A. (Editor)

    1991-01-01

    The purpose of this handbook is to provide background data on current, approved, and planned missions, including a summary of the recommended candidate future missions. Topics include the space physics mission plan, operational spacecraft, and details of such approved missions as the Tethered Satellite System, the Solar and Heliospheric Observatory, and the Atmospheric Laboratory for Applications and Science.

  17. 75 FR 24394 - Animal Drugs, Feeds, and Related Products; Withdrawal of Approval of a New Animal Drug...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-05

    ... [Docket No. FDA-2010-N-0002] Animal Drugs, Feeds, and Related Products; Withdrawal of Approval of a New Animal Drug Application; Buquinolate; Coumaphos AGENCY: Food and Drug Administration, HHS. ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations by...

  18. 77 FR 150 - Information Collection Available for Public Comments and Recommendations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-03

    ... Approval: Three years from date of approval by the Office of Management and Budget. Summary of Collection... Academy Application for Admission). Part I of the form is completed by individuals wishing to be admitted as students to the U.S. Merchant Marine Academy. Need and Use of the Information: The information is...

  19. 78 FR 64984 - Extension of the Approval of Information Collection Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-30

    ... DEPARTMENT OF LABOR Wage and Hour Division RIN 1235-0018 Extension of the Approval of Information Collection Requirements AGENCY: Wage and Hour Division, Department of Labor. ACTION: Notice. SUMMARY: The Paperwork Reduction Act of 1995 (PRA), 44 U.S.C. 3501 et seq., and its attendant regulations, 5 CFR part...

  20. 76 FR 4430 - Summary of Precedent Opinions of the General Counsel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-25

    ... veteran or person who is already qualified by training and experience for the job'' preclude approval of an on-the-job training (OJT) program for employees of State approving agencies (SAA) who are... these employees are already qualified by training and experience for the job. Because we have determined...

  1. 76 FR 58210 - Approval and Promulgation of Implementation Plans and Designation of Areas for Air Quality...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-20

    ... Nonattainment Area to Attainment AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY... four separate but related actions. First, EPA is proposing to approve the December 18, 2009, PM 2.5 redesignation request, including the December 22, 2010, Motor Vehicle Emission Simulator (MOVES) mobile model...

  2. 77 FR 65125 - Approval and Promulgation of Implementation Plans; Georgia 110(a)(1) and (2) Infrastructure...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-25

    ... controls are enforced through the associated SIP rules or Federal Implementation Plans (FIPs). Any purchase... Promulgation of Implementation Plans; Georgia 110(a)(1) and (2) Infrastructure Requirements for the 1997 and... Agency (EPA). ACTION: Final rule. SUMMARY: EPA is taking final action to approve the State Implementation...

  3. Regulatory Approval of Cancer Risk-reducing (Chemopreventive) Drugs: Moving What We Have Learned into the Clinic

    PubMed Central

    Meyskens, Frank L.; Curt, Gregory A.; Brenner, Dean E.; Gordon, Gary; Herberman, Ronald B.; Finn, Olivera; Kelloff, Gary J.; Khleif, Samir N.; Sigman, Caroline C.; Szabo, Eva

    2010-01-01

    This paper endeavors to clarify the current requirements and status of regulatory approval for chemoprevention (risk reduction) drugs and discusses possible improvements to the regulatory pathway for chemoprevention. Covering a wide range of topics in as much depth as space allows, this report is written in a style to facilitate the understanding of non-scientists and to serve as a framework for informing the directions of experts engaged more deeply with this issue. Key topics we cover here are as follows: a history of definitive cancer chemoprevention trials and their influence on the evolution of regulatory assessments; a brief review of the long-standing success of pharmacologic risk reduction of cardiovascular diseases and its relevance to approval for cancer risk reduction drugs; the use and limitations of biomarkers for developing and the approval of cancer risk reduction drugs; the identification of individuals at a high(er) risk for cancer and who are appropriate candidates for risk reduction drugs; business models that should incentivize pharmaceutical-industry investment in cancer risk reduction; a summary of scientific and institutional barriers to development of cancer risk reduction drugs; and a summary of major recommendations that should help facilitate the pathway to regulatory approval for pharmacologic cancer risk reduction drugs. PMID:21372031

  4. 78 FR 37126 - Approval and Promulgation of Implementation Plans; State of Kansas; Infrastructure SIP...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-20

    ... (EPA). ACTION: Final rule. SUMMARY: EPA is finalizing approval of four Kansas State Implementation Plan... of proposed rulemaking for this action, which was published on April 17, 2013. DATES: This rule will... those portions in the April 17, 2013, proposed rule since they had already been acted upon by EPA. With...

  5. 77 FR 26277 - Agency Information Collection Activities: Final Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-03

    ... Review and Comments Request. Form Title: EIB 99-14 Export Import Bank Trade Reference form. SUMMARY: The... requesting an emergency approval of Ex-Im Bank form EIB 99-14 Export Import Bank Trade Reference form. Export-Import (Ex- Im) Bank is requesting an emergency approval of form EIB 99-14, Trade Reference Form. This...

  6. 75 FR 25772 - Approval and Promulgation of Air Quality Implementation Plans; Colorado; Revisions to Regulation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-10

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R08-OAR-2009-0790; FRL-9114-3] Approval and...: Environmental Protection Agency (EPA). ACTION: Direct final rule. SUMMARY: EPA is taking direct final action..., Environmental Protection Agency (EPA), Region 8, Mailcode 8P-AR, 1595 Wynkoop Street, Denver, Colorado 80202...

  7. 77 FR 64343 - Notice of Availability: Test Tools and Test Procedures Approved for the Office of the National...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-19

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Notice of Availability: Test Tools and Test Procedures.... SUMMARY: This notice announces the availability of test tools and test procedures approved by the National... test tools and test procedures are identified on the ONC Web site at: http://www.healthit.gov/policy...

  8. 21 CFR 514.11 - Confidentiality of data and information in a new animal drug application file.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... two alternative ways shall be publicly released when the approval is published in the Federal Register. (a) The Center for Veterinary Medicine may at an appropriate time prior to approval of the NADA... appropriate, revised by the Center. (b) The Center for Veterinary Medicine may prepare its own summary of such...

  9. 21 CFR 514.11 - Confidentiality of data and information in a new animal drug application file.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... two alternative ways shall be publicly released when the approval is published in the Federal Register. (a) The Center for Veterinary Medicine may at an appropriate time prior to approval of the NADA... appropriate, revised by the Center. (b) The Center for Veterinary Medicine may prepare its own summary of such...

  10. 21 CFR 514.11 - Confidentiality of data and information in a new animal drug application file.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... two alternative ways shall be publicly released when the approval is published in the Federal Register. (a) The Center for Veterinary Medicine may at an appropriate time prior to approval of the NADA... appropriate, revised by the Center. (b) The Center for Veterinary Medicine may prepare its own summary of such...

  11. A Technology Solution Strengthens Comprehensive Environmental Management

    DTIC Science & Technology

    2012-05-23

    General Navigation  Chemical Approval Example  NEPA Coordination Example  Safety PPE Example  Summary Marine Corps Support Facility...coordination, completion and documentation through automated workflows of various business processes  Chemical Approval  NEPA Coordination  Safety ...Completion Diagram Government Employee/M CMC MCMC Chemical Manager MCMC HS&E Specialist IMO Chemical Safety Specialist IMO Chemical Environmental

  12. 76 FR 65485 - Petition for Approval of Alternate Odometer Disclosure Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-21

    ... is subject to review during on-site audits by NYSDMV. When a New York dealer sells a vehicle to a... review the vehicle's data and odometer disclosure on New York's system and compare it to the paper... determination. SUMMARY: The State of New York has petitioned for approval of alternate odometer requirements to...

  13. 76 FR 4710 - Accreditation and Approval of Laboratory Service, Inc., as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-26

    ... Laboratory Service, Inc., as a Commercial Gauger and Laboratory AGENCY: U.S. Customs and Border Protection, Department of Homeland Security. ACTION: Notice of accreditation and approval of Laboratory Service, Inc., as a commercial gauger and laboratory. SUMMARY: Notice is hereby given that, pursuant to 19 CFR 151.12...

  14. A Preliminary Analysis of the Outcomes of Students Assisted by VET FEE-HELP: Summary

    ERIC Educational Resources Information Center

    National Centre for Vocational Education Research (NCVER), 2015

    2015-01-01

    This summary highlights the key findings from the report "A preliminary analysis of the outcomes of students assisted by VET FEE-HELP". VET FEE-HELP is an income-contingent loan scheme that assists eligible students undertaking certain vocational education training (VET) courses with an approved provider by paying for all or part of…

  15. Executive Summary of the American Heart Association and American Thoracic Society Joint Guidelines for Pediatric Pulmonary Hypertension

    PubMed Central

    Ivy, D. Dunbar; Archer, Stephen L.; Wilson, Kevin

    2016-01-01

    Although pulmonary hypertension (PH) contributes significantly to poor outcomes in diverse pediatric diseases, approaches toward the care of children with PH have been limited by the lack of consensus guidelines from experts in the field. In a joint effort from the American Heart Association and American Thoracic Society, a committee of experienced clinicians was formed to systematically identify, synthesize, and appraise relevant evidence and then to formulate evidence-based recommendations regarding the diagnosis and management of pediatric PH. This brief report is an executive summary of the officially approved guidelines developed by the committee, highlighting a few key recommendations regarding the care of children with PH. Guidelines and the rationale for grading the strength of each recommendation are included in the online supplement. PMID:27689707

  16. Comparing two botulinum toxin type A formulations using manufacturers' product summaries.

    PubMed

    Wenzel, R; Jones, D; Borrego, J A

    2007-08-01

    Because of the unique pharmacology and clinical versatility of botulinum toxin (BoNT), particularly BoNT serotype A (BoNTA), a need exists for discussion of the current data on similarities and differences between two BoNTA products, BOTOX and Dysport. We compared the physiochemical and pharmacological properties of BOTOX and Dysport using information from the Summary of Product Characteristics (SmPC) documents from a number of countries around the world. Our analysis based on the SmPC documents demonstrated distinct differences in physical characteristics, breadth of approved indications, dosing and administration, and the incidence and severity of adverse events. BOTOX and Dysport are not bioequivalent. Many of the differences between BOTOX and Dysport discussed within are probably related to the differences in their physical characteristics.

  17. Aseptic Bone Necrosis Among U.S. Navy Divers: Survey of 934 Nonrandomly Selected Personnel

    DTIC Science & Technology

    1977-06-01

    Health, Education, and Welfare, Washington, D.C. Kawashima, M., T. Torisu, K. Hayashi, and Y. Kamo. 1974. Avascular bone necrosis in Japanese diving...5ÜL ^4- P=- 7 RESEM^a^ATORY SUBMARINE BASE, GROTON, CONN. REPORT NUMBER 854 ASEPTIC BONE NECROSIS AMONG U. S. NAVY DIVERS: Survey of 934...Approved for public release; distribution unlimited SUMMARY PAGE THE PROBLEM Aseptic boire~ necrosis tABN) has beelTknown toT5e~ associated with

  18. Rare Cell Separation and Analysis by Magnetic Sorting

    PubMed Central

    Zborowski, Maciej; Chalmers, Jeffrey J.

    2011-01-01

    Summary The separation and or isolation of rare cells using magnetic forces is commonly used and growing in use ranging from simple sample prep for further studies to a FDA approved, clinical diagnostic test. This grown is the result of both the demand to obtain homogeneous rare cells for molecular analysis and the dramatic increases in the power of permanent magnets that even allow the separation of some unlabeled cells based on intrinsic magnetic moments, such as malaria parasite-infected red blood cells. PMID:21812408

  19. 76 FR 4250 - Operating Certain Railroad Tank Cars in Excess of 263,000 Pounds Gross Rail Load; Approval

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-25

    ... Railroad Tank Cars in Excess of 263,000 Pounds Gross Rail Load; Approval AGENCY: Federal Railroad... certain railroad tank cars in excess of 263,000 pounds gross rail load. SUMMARY: On May 14, 2010, the... to allow certain rail tank cars, transporting hazardous materials, to exceed the gross weight on rail...

  20. 78 FR 38223 - Approval and Promulgation of Implementation Plans; Designation of Areas for Air Quality Planning...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-26

    ... demonstration showing how the area will continue to attain the 24-hour PM 10 NAAQS for at least 10 years beyond...; California; South Coast Air Basin; Approval of PM 10 Maintenance Plan and Redesignation to Attainment for the PM 10 Standard AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY: EPA is...

  1. Vocations: The Link between Post-Compulsory Education and the Labour Market. What the Research Says For... Qualification & Approval Bodies

    ERIC Educational Resources Information Center

    Wheelahan, Leesa; Buchanan, John; Yu, Serena

    2015-01-01

    This summary pulls together the relevant key findings for qualification and approval bodies from the research program "Vocations: The Link between Post-Compulsory Education and the Labour Market." The program was comprised of three different strands: (1) pathways from VET in Schools, (2) pathways within and between vocational education…

  2. Honey-based dressings and wound care: an option for care in the United States.

    PubMed

    Pieper, Barbara

    2009-01-01

    Honey-based wound dressings have been used worldwide since ancient times. A honey product received US Federal Drug Administration approval in 2007, making this dressing an option for wound care. Honey has been found to exert anti-inflammatory and antibacterial effects without antibiotic resistance, promote moist wound healing, and facilitate debridement. However, it may cause a stinging pain. As is true of any wound dressing, its use must be carefully selected and monitored. Continued research is needed to add to its evidence base. This article provides a summary of the current evidence base for the use of honey and a review of its therapeutic effects and discusses implications for WOC nursing practice.

  3. 76 FR 76684 - Idaho: Tentative Approval of State Underground Storage Tank Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-08

    .... Skyline, Suite B, Idaho Falls, ID 83402 from 10 a.m. to 12 p.m. and 1 p.m. to 4 p.m.; and 6. IDEQ Lewiston... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 281 [EPA-R10-UST-2011-0896; FRL-9502-6] Idaho...). ACTION: Proposed rule. SUMMARY: The State of Idaho has applied for final approval of its Underground...

  4. Development and Validation of a Porcine (Sus scrofa) Sepsis Model

    DTIC Science & Technology

    2018-03-01

    last IACUC approval, have any methods been identified to reduce the number of live animals used in this protocol? None 10. PUBLICATIONS...SUMMARY: (Please provide, in "ABSTRACT" format, a summary of the protocol objectives, materials and methods , results - include tables/figures, and...Materials and methods : Animals were anesthetized and instrumented for cardiovascular monitoring. Lipopolysaccharide (LPS, a large molecule present on the

  5. A guide to the proper selection and use of federally approved sediment and water-quality samplers

    USGS Publications Warehouse

    Davis, Broderick E.; ,

    2005-01-01

    As interest in the health of rivers and streams increases3, and new water-quality regulations4 are promulgated, interest in sediment and water-quality sampling equipment and technologies has increased. While much information on the subject exists, a comprehensive summary document of sediment sampling equipment and technology is lacking. This report seeks to provide such a summary.

  6. Comparison of treatment effect sizes from pivotal and postapproval trials of novel therapeutics approved by the FDA based on surrogate markers of disease: a meta-epidemiological study.

    PubMed

    Wallach, Joshua D; Ciani, Oriana; Pease, Alison M; Gonsalves, Gregg S; Krumholz, Harlan M; Taylor, Rod S; Ross, Joseph S

    2018-03-21

    The U.S. Food and Drug Administration (FDA) often approves new drugs based on trials that use surrogate markers for endpoints, which involve certain trade-offs and may risk making erroneous inferences about the medical product's actual clinical effect. This study aims to compare the treatment effects among pivotal trials supporting FDA approval of novel therapeutics based on surrogate markers of disease with those observed among postapproval trials for the same indication. We searched Drugs@FDA and PubMed to identify published randomized superiority design pivotal trials for all novel drugs initially approved by the FDA between 2005 and 2012 based on surrogate markers as primary endpoints and published postapproval trials using the same surrogate markers or patient-relevant outcomes as endpoints. Summary ratio of odds ratios (RORs) and difference between standardized mean differences (dSMDs) were used to quantify the average difference in treatment effects between pivotal and matched postapproval trials. Between 2005 and 2012, the FDA approved 88 novel drugs for 90 indications based on one or multiple pivotal trials using surrogate markers of disease. Of these, 27 novel drugs for 27 indications were approved based on pivotal trials using surrogate markers as primary endpoints that could be matched to at least one postapproval trial, for a total of 43 matches. For nine (75.0%) of the 12 matches using the same non-continuous surrogate markers as trial endpoints, pivotal trials had larger treatment effects than postapproval trials. On average, treatment effects were 50% higher (more beneficial) in the pivotal than the postapproval trials (ROR 1.5; 95% confidence interval CI 1.01-2.23). For 17 (54.8%) of the 31 matches using the same continuous surrogate markers as trial endpoints, pivotal trials had larger treatment effects than the postapproval trials. On average, there was no difference in treatment effects between pivotal and postapproval trials (dSMDs 0.01; 95% CI -0.15-0.16). Many postapproval drug trials are not directly comparable to previously published pivotal trials, particularly with respect to endpoint selection. Although treatment effects from pivotal trials supporting FDA approval of novel therapeutics based on non-continuous surrogate markers of disease are often larger than those observed among postapproval trials using surrogate markers as trial endpoints, there is no evidence of difference between pivotal and postapproval trials using continuous surrogate markers.

  7. Martin Marietta Airfield, Baltimore, Maryland. Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F

    DTIC Science & Technology

    1979-08-02

    FOR PUBLIC RELEASE AND SALE , ITS DIS. TRIBUTION IS UNLIMITED." S5g-4420 b Review and Approval Statement This report is approved for public release...IARIETTA AIRFIEL) MIj) ඏ-78 APR STATION ITATINI Nae ITUN m ALL hFATHF. , 0600-0800 CLAN NOVE (L.,T,) CONDITION SPEED ] MUAN (KNTS) 1 3 4. 6 7- 10 11 •1 1

  8. Transition from Terrorist Event Management to Consequence Management, Executive Summary

    DTIC Science & Technology

    1982-03-31

    8217 "This report has been reviewed in the Federal Emergency Management Agency and approved for puLlication. Approval does not signify that the contents...acts. It describes in general terms what mechanism is in place today. This description is derived from documentation reviewed and information obtained...probabilities was employed in the development of the- values expressed in the matrices. Probabilities were established by a review of several previous

  9. Evaluation of Catalyst Activity - Detoxification of Chemical Warfare Agents Under Oxidation and Hydrolysis Conditions

    DTIC Science & Technology

    2006-08-15

    Report August 15, 2006 CUBRC Contract No.: 6774 Prime Contract No.: W911-NF-05-C-0041 Subcontract No.:CBR05.1 Submitted to: TDA... CUBRC Approval: 8/15/06 David J. Mangino – Director, Life Sciences Date CUBRC 2 of 40 Contents 1. SUMMARY...POSSIBLE HYDROLYSIS DEGRADATION PRODUCTS – MASS SPECTRA ............36 CUBRC 3 of 40 1. SUMMARY Potential catalysts for the

  10. Test Results of Air-Permeable Charcoal Impregnated Suits to Challenge by Chemical and Biological Warfare Agents and Simulants. Executive Summary and Summary Report

    DTIC Science & Technology

    2003-05-01

    authorizing documents. REPORT DOCUMENTATION PAGE F ~ormApprove I OMB No. 0704-0188 Public reporting burden for this collection of Information Is...Health, San Antonio, TX e Dr. Annetta P. Watson, Life Sciences Division, Oak Ridge National Laboratories, Oak Ridge, TN 9 Leo F . Saubier, Battelle Memorial...37 F - Giat NBC SWAT Suit ........................................................... 43 G - Giat

  11. 77 FR 1782 - Petition for Exemption; Summary of Petition Received

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-11

    ... any personal information you provide. Using the search function of our docket web site, anyone can... systems without giving approval for automatic activation devices (AAD). Parachute Labs provides...

  12. 33 CFR 105.410 - Submission and approval.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... operational characteristics of each facility and must complete a separate Facility Vulnerability and Security Measures Summary (Form CG-6025), in appendix A to part 105—Facility Vulnerability and Security Measures...

  13. Zoster vaccine live for the prevention of shingles in the elderly patient

    PubMed Central

    Zussman, Jamie; Young, Lorraine

    2008-01-01

    Shingles, also known as herpes zoster, is a common disease in the elderly population that is caused by reactivation of latent varicella zoster virus. Its manifestations and complications can lead to significant short- and long-term morbidity. In 2006, the United States Food and Drug Administration approved Zoster Vaccine Live (Zostavax®) for the prevention of herpes zoster in immunocompetent adults age 60 and over. The approval was based on the results of a large, multi-center clinical trial, the Shingles Prevention Study. This study showed that vaccination significantly decreased shingles incidence, burden of illness due to disease, and the development of, and severity of postherpetic neuralgia. This review offers an overview of varicella zoster virus infection and complications, a summary of the Shingles Prevention Study, and a critical analysis designed to aid the practicing physician who has questions about vaccine administration. PMID:18686747

  14. Executive Summary: The SRI-WEFA Soviet Econometric Model: Phase One Documentation

    DTIC Science & Technology

    1975-03-01

    DEPARTMENT OF COMMERCE JHiiriuTn.. O 0 n-^ ^ isnmnii/ivuuwun MB * < Report Categories: The research outn ,t by the Strategic Studies Center is...research as well as the general method- ology employed. The reports are previewed and approved by the Director of the Strategic Studies Center or higher...than rormally edited, printed, and bound in standard SRI covers. The reports are reviewed and approved by the Director of the Strategic Studies

  15. 12 CFR 708b.106 - Approval of the merger proposal by members.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... summary of the merger plan, including, but not necessarily limited to, current financial statements for each credit union, a consolidated financial statement for the continuing credit union, analyses of...

  16. Molecular Methods and Platforms for Infectious Diseases Testing

    PubMed Central

    Emmadi, Rajyasree; Boonyaratanakornkit, Jerry B.; Selvarangan, Rangaraj; Shyamala, Venkatakrishna; Zimmer, Barbara L.; Williams, Laurina; Bryant, Bonita; Schutzbank, Ted; Schoonmaker, Michele M.; Amos Wilson, Jean A.; Hall, Leslie; Pancholi, Preeti; Bernard, Kathryn

    2011-01-01

    The superior sensitivity and specificity associated with the use of molecular assays has greatly improved the field of infectious disease diagnostics by providing clinicians with results that are both accurate and rapidly obtained. Herein, we review molecularly based infectious disease diagnostic tests that are Food and Drug Administration approved or cleared and commercially available in the United States as of December 31, 2010. We describe specific assays and their performance, as stated in the Food and Drug Administration's Summary of Safety and Effectiveness Data or the Office of In Vitro Diagnostic Device Evaluation and Safety's decision summaries, product inserts, or peer-reviewed literature. We summarize indications for testing, limitations, and challenges related to implementation in a clinical laboratory setting for a wide variety of common pathogens. The information presented in this review will be particularly useful for laboratories that plan to implement or expand their molecular offerings in the near term. PMID:21871973

  17. Signal Processing in Reverberation- A Summary of Performance Capability

    DTIC Science & Technology

    1972-08-30

    34 LkP+52-DOGLB. UNCLASSIFIED N, TM No. TC- 173-72 LC INAVAL UNDERWATER SYSTEMS CENTER Technical Memorandum SIGNAL PROCESSING IN REVERBERATION- A...SUMMARY OF PERFORMANCE CAPABILITY Date: 30 August 1972 Prepared by: -- v i Alert H. Nuttall Office of the Director of Science and Technology 2TICELECTEI...Nuffall Office of the Director of Science and Technology Approved for public release; distribution unlimited UNCLASSIFIED TM No. TC- I7P-72 NAVAL

  18. Communications Processor Operating System Study. Executive Summary,

    DTIC Science & Technology

    1980-11-01

    AD-A095 b36 ROME AIR DEVELOPMENT CENTER GRIFFISS AFB NY F/e 17/2 COMMUNICATIONS PROCESSOR OPERATING SYSTEM STUDY. EXECUTIVE SUMM—ETC(U) NOV 80 J...COMMUNICATIONS PROCESSOR OPERATING SYSTEM STUDY Julian Gitlih SPTIC ELECTE«^ FEfi 2 6 1981^ - E APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED "a O...Subtitle) EXECUTIVE^SUMMARY 0F> COMMUNICATIONS PROCESSOR OPERATING SYSTEM $t - • >X W tdLl - ’•• • 7 AUTHORf«! ! , Julian

  19. From Paper to Practice: Challenges Facing a California Charter School. A Report Presented to the San Diego Unified School Board. Executive Summary.

    ERIC Educational Resources Information Center

    WestEd, San Francisco, CA.

    Signed into law on September 2, 1992, California's charter-school law has led to the approval of over 100 charter schools. San Diego City Schools (SDCS) was one of the first districts to sponsor charter schools, including the Harriet Tubman School, 1 year after the law became effective. This document provides a brief overview and summary of a case…

  20. Therapeutic Targeting of Lipid Droplets as Disease Markers in Ovarian Cancer

    DTIC Science & Technology

    2016-03-01

    COVERED (From - To) 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 5d. PROJECT NUMBER 5e. TASK NUMBER 5f...CONTENTS Page # INTRODUCTION 2 KEYWORDS 2 PROJECT SUMMARY 2-9 KEY RESEARCH ACCOMPLISHMENTS 10 CONCLUSION AND FUTIRE PLANS 10 PUBLICATION/ABSTRACTS...Time to Recurrence, PFS- Progression Free Survival, OS-Overall Survival 3. OVERALL PROJECT SUMMARY: Milestone 1: Animal Use Approval-Prepare IACUC

  1. U.S. Food and Drug Administration Approval Summary: Ramucirumab for the Treatment of Metastatic Non-Small Cell Lung Cancer Following Disease Progression On or After Platinum-Based Chemotherapy.

    PubMed

    Larkins, Erin; Scepura, Barbara; Blumenthal, Gideon M; Bloomquist, Erik; Tang, Shenghui; Biable, Missiratch; Kluetz, Paul; Keegan, Patricia; Pazdur, Richard

    2015-11-01

    On December 12, 2014, the U.S. Food and Drug Administration (FDA) approved ramucirumab for use in combination with docetaxel for the treatment of patients with metastatic non-small cell lung cancer (NSCLC) with disease progression on or after platinum-based chemotherapy. Patients with epidermal growth factor receptor or anaplastic lymphoma kinase genomic tumor aberrations should have disease progression on FDA-approved therapy for these aberrations prior to receiving ramucirumab. This approval was based on an improvement in overall survival (OS) with an acceptable toxicity profile in a randomized, multicenter, double-blinded, placebo-controlled trial of 1,253 patients with metastatic NSCLC previously treated with a platinum-based combination therapy. Patients were randomized 1:1 to receive either ramucirumab in combination with docetaxel or placebo in combination with docetaxel. The primary endpoint was OS. Patients who received ramucirumab in combination with docetaxel had improved OS (hazard ratio [HR]: 0.86; 95% confidence interval [CI]: 0.75, 0.98). Median OS was 10.5 months on the ramucirumab plus docetaxel arm versus 9.1 months on the placebo plus docetaxel arm. The most frequent (≥ 30%) adverse reactions in ramucirumab-treated patients were fatigue, neutropenia, and diarrhea. The most frequent (≥ 5%) grade 3 and 4 adverse reactions in the ramucirumab arm were fatigue, neutropenia, febrile neutropenia, leukopenia, and hypertension. This report presents key information on the U.S. Food and Drug Administration approval of ramucirumab, a monoclonal antibody targeting vascular endothelial growth factor receptor-2, given in combination with docetaxel for the treatment of patients with metastatic non-small cell lung cancer whose disease has progressed on or after platinum-based chemotherapy. This report specifically addresses the issues of safety in patients with squamous cell tumors, effect of treatment in elderly patients, and uncertainties regarding effects in patients with tumors harboring epidermal growth factor receptor or anaplastic lymphoma kinase genomic tumor aberrations. ©AlphaMed Press.

  2. Treatment of severe psoriasis in children: recommendations of an Italian expert group.

    PubMed

    Fortina, Anna Belloni; Bardazzi, Federico; Berti, Samantha; Carnevale, Claudia; Di Lernia, Vito; El Hachem, Maya; Neri, Iria; Gelmetti, Carlo Mario; Lora, Viviana; Mazzatenta, Carlo; Milioto, Mirella; Moretta, Gaia; Patrizi, Annalisa; Peris, Ketty; Villani, Alberto

    2017-10-01

    This article provides comprehensive recommendations for the systemic treatment of severe pediatric psoriasis based on evidence obtained from a systematic review of the literature and the consensus opinion of expert dermatologists and pediatricians. For each systemic treatment, the grade of recommendation (A, B, C) based on the treatment's approval by the European Medicines Agency for childhood psoriasis and the experts' opinions is discussed. The grade of recommendation for narrow-band-ultraviolet B phototherapy, cyclosporine, and retinoids is C, while that for methotrexate is C/B. The use of adalimumab, etanercept, and ustekinumab has a grade A recommendation. No conventional systemic treatments are approved for pediatric psoriasis. Adalimumab is approved by the European Medicines Agency as a first-line treatment for severe chronic plaque psoriasis in children (≥ 4 years old) and adolescents. Etanercept and ustekinumab are approved as second-line therapy in children ≥ 6 and ≥ 12 years, respectively. A treatment algorithm as well as practical tools (i.e., tabular summaries of differential diagnoses, treatment mechanism of actions, dosing regimens, control parameters) are provided to assist in therapeutic reasoning and decision-making for individual patients. These treatment recommendations are endorsed by major Italian Pediatric and Dermatology Societies. What is Known: • Guidelines for the treatment of severe pediatric psoriasis are lacking and most traditional systemic treatments are not approved for use in young patients. Although there has been decades of experience with some of the traditional agents such as phototherapy, acitretin, and cyclosporine in children, there are no RCTs on their pediatric use while RCTs investigating new biologic agents have been performed. What is New: • In this manuscript, an Italian multidisciplinary team of experts focused on treatment recommendations for severe forms of psoriasis in children based on an up-to-date review of the literature and experts' opinions.

  3. Compilation of current high energy physics experiments - Sept. 1978

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Addis, L.; Odian, A.; Row, G. M.

    1978-09-01

    This compilation of current high-energy physics experiments is a collaborative effort of the Berkeley Particle Data Group, the SLAC library, and the nine participating laboratories: Argonne (ANL), Brookhaven (BNL), CERN, DESY, Fermilab (FNAL), KEK, Rutherford (RHEL), Serpukhov (SERP), and SLAC. Nominally, the compilation includes summaries of all high-energy physics experiments at the above laboratories that were approved (and not subsequently withdrawn) before about June 1978, and had not completed taking of data by 1 January 1975. The experimental summaries are supplemented with three indexes to the compilation, several vocabulary lists giving names or abbreviations used, and a short summary ofmore » the beams at each of the laboratories (except Rutherford). The summaries themselves are included on microfiche. (RWR)« less

  4. Station Climatic Summaries, North America.

    DTIC Science & Technology

    1988-08-01

    8603 (CB) ..................................... 371 MI IIGA ALPENA (PHELPS-COLLINS FIELD) 726390 8710 (Ce) ..................................... 372...direction APPROVED FOR PUBLIC RELEASE; DISTRIBUTION IS UNLIMITED 372 A W S Station Name: PHELPS-MOLLINS/ ALPENA KI Field Klev: 689 ft CLIMATIC BRIEF

  5. 2012-2016 Highway Program summary : approved June 2011.

    DOT National Transportation Integrated Search

    2011-06-01

    The Iowa Transportation Commission (Commission) and the Iowa Department of : Transportation (Iowa DOT) develop Iowas Five Year Highway Program to inform : Iowans of planned investments in our states primary highway system. This : brochure summa...

  6. 78 FR 76293 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-17

    ... Wastewater Laboratories (Renewal) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: The... Studies on Wastewater Laboratories (Renewal)'' to the Office of Management and Budget (OMB) for review and...

  7. 78 FR 40760 - 60-Day Notice of Proposed Information Collection: Training Evaluation Form

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-08

    ... Indian Housing, HUD. ACTION: Notice. SUMMARY: HUD is seeking approval from the Office of Management and... instrument to evaluate learners' reactions to training or technical assistance programs. With the information...

  8. 76 FR 40734 - Agency Information Collection Activities; Announcement of Office of Management and Budget...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-11

    ...; Voluntary Cosmetic Registration Program AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY... ``Voluntary Cosmetic Registration Program'' has been approved by the Office of Management and Budget [[Page...

  9. B-70 Aircraft Study. Volume 1

    NASA Technical Reports Server (NTRS)

    Johnson, V. T.

    1972-01-01

    This Phase 2 final report for the B-70 aircraft study contains the data location matrix, which provides a summary of the major cost, schedule, and technical items provided in the report; work breakdown structure; cost definitions; and B-70 program level summary data. The Phase 2 objective was to provide the B-70 aircraft data in accordance with the approved study plan. Several minor modifications to the original plan have been made as the result of the Phase 2 effort.

  10. Combating Terrorism Within Local Policing Through Crime Reduction: Using Real-Time, Situational Awareness Within a Distributed Common Operating Picture to Combat all Crime and Terrorism V2I2SION Process and SAFECOP Pilot Project

    DTIC Science & Technology

    2013-03-01

    Occurred on: Jul-07-2011 (Tbu.) 248 Approved on: Jul-07-2011 (Tbu.) by: 42505 - BAXTER, ROBERT M Report submitted by: 45158 - CHARBONNEAU , PETER A...Text Page(s) Document: CASE SUM:MARY Author: 45158- CHARBONNEAU , PETER A Subject: CASE SUM:MARY Related date/time: Jul-07-2011 (Tbu.) 248 On the

  11. 78 FR 35284 - Medical Devices; Availability of Safety and Effectiveness Summaries for Premarket Approval...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-12

    .... Stent Graft System. P040046, FDA-2013-M-0255 Allergan Natrelle[supreg] 410 February 20, 2013. Highly... Vascular, Resolute Integrity February 22, 2013. Inc. Zotarolimus-Eluting Coronary Stent System. P100030...

  12. 76 FR 16033 - 60-Day Notice of Proposed Information Collection: Bureau of Educational and Cultural Affairs...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-22

    .... SUMMARY: The Department of State is seeking Office of Management and Budget (OMB) approval for the...: Survey numbers (SV-yyyy- ) will be generated as needed. Respondents: International Visitor Leadership...

  13. 76 FR 78966 - Federal Aviation Administration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-20

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Approval of Noise Compatibility Program for Kona International Airport at Keahole, Keahole, North Kona, HI AGENCY: Federal Aviation Administration, DOT. ACTION: Notice. SUMMARY: The Federal Aviation Administration (FAA) announces its findings on...

  14. 78 FR 38795 - Agency Information Collection Activities: Requests for Comments; Clearance of Renewed Approval of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-27

    ... comments. SUMMARY: In accordance with the Paperwork Reduction Act of 1995, FAA invites public comments... profit organizations, and profit organizations for security research. The collection of data is required...

  15. Smart sign ordering system : executive summary report.

    DOT National Transportation Integrated Search

    2004-05-01

    Problem: The districts submit sign orders to the Sign Shop, : where all approved orders are processed in : production planning, fabrication, and subsequent : shipping. Due to lack of data automation and : efficient means of data exchange and manageme...

  16. 34 CFR 97.117 - Documentation of informed consent.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Policy for the Protection of Human Subjects (Basic ED Policy for Protection of Human Research Subjects... presentation. Also, the IRB shall approve a written summary of what is to be said to the subject or the...

  17. 34 CFR 97.117 - Documentation of informed consent.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Policy for the Protection of Human Subjects (Basic ED Policy for Protection of Human Research Subjects... presentation. Also, the IRB shall approve a written summary of what is to be said to the subject or the...

  18. 34 CFR 97.117 - Documentation of informed consent.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Policy for the Protection of Human Subjects (Basic ED Policy for Protection of Human Research Subjects... presentation. Also, the IRB shall approve a written summary of what is to be said to the subject or the...

  19. 34 CFR 97.117 - Documentation of informed consent.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Policy for the Protection of Human Subjects (Basic ED Policy for Protection of Human Research Subjects... presentation. Also, the IRB shall approve a written summary of what is to be said to the subject or the...

  20. 76 FR 70768 - Biweekly Notice; Applications and Amendments to Facility Operating Licenses Involving No...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-15

    ... perform a probabilistic risk evaluation using the guidance contained in NRC approved NEI [Nuclear Energy... Issue Summary 2003-18, Supplement 2, ``Use of Nuclear Energy Institute (NEI) 99-01, Methodology for...

  1. 10 CFR 905.15 - What are the requirements for the small customer plan alternative?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... summary form the following information: (i) Customer name, address, phone number, email and Website if... approves the request for small customer status. Small customers must submit, in writing, a small customer...

  2. Minutes of the third annual meeting of the Panel on Reference Nuclear Data. [BNL, October 5, 1978

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burrows, T.W.; Stewart, L.; Coyne, J.J.

    1979-05-01

    The major activities of the meeting were as follows: welcome; organization, approval of minutes of the second meeting, and approval of agenda; review of nuclear data compilation and evaluation efforts (national and international efforts, master data files, publications); summary of 1977 panel meeting; definition of reference nuclear data; discussion of specific data needs and possible data center contributions (reactor physics, medicine and biology, controlled thermonuclear reactors and astrophysics); establishment of current interest and future direction of the panel; adjournment. Recommendations and action items are listed. Tables on nuclear data needs in applied physics, medicine and biology, and controlled thermonuclear reactorsmore » and astrophysics are presented. Appendixes include membership lists of various committees, summaries of publication activities, survey results, correspondence, and portions of the documents Proceedings of the Magnetic Fusion Energy Blanket and Shield Workshop and National Needs for Critically Evaluated Physical and Chemical Data. (RWR)« less

  3. Riyadh, Saudi Arabia Limited Surface Observations Climatic Summary (LISOCS). Parts A, C-F.

    DTIC Science & Technology

    1985-06-01

    ASHEVILLE, N. C.OC B 85 10 03 .022 85 10 03 C22 REVIEW AND £PPBOVAL STAMMT This report is approved for public release. There is no objection to unlimited...Service (NTIS). Th~s technical report has been reviewed and i approved for publication. FOR THE COHMANDEB Qefa, Docummnt 3mmaicb Section UMAMEAC/LDX I p N...8217 REPORT DOCUMENTATION PAGE Ma. REPOT SECUNiTY CLASSIFICATIO 1b. RESTRICTIVE MARKINGS- unclassified_______________________ 24. SCUiMM CIASSIFICATION

  4. CLOSURE REPORT FOR CORRECTIVE ACTION UNIT 528: POLYCHLORINATED BIPHENYLS CONTAMINATION NEVADA TEST SITE, NEVADA

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    BECHTEL NEVADA

    2006-09-01

    This Closure Report (CR) describes the closure activities performed at CAU 528, Polychlorinated Biphenyls Contamination, as presented in the Nevada Division of Environmental Protection (NDEP)-approved Corrective Action Plan (CAP) (US. Department of Energy, National Nuclear Security Administration Nevada Site Office [NNSAINSO], 2005). The approved closure alternative was closure in place with administrative controls. This CR provides a summary of the completed closure activities, documentation of waste disposal, and analytical data to confirm that the remediation goals were met.

  5. FDA Approval Summary: Atezolizumab for the Treatment of Patients with Progressive Advanced Urothelial Carcinoma after Platinum‐Containing Chemotherapy

    PubMed Central

    Suzman, Daniel; Maher, V. Ellen; Zhang, Lijun; Tang, Shenghui; Ricks, Tiffany; Palmby, Todd; Fu, Wentao; Liu, Qi; Goldberg, Kirsten B.; Kim, Geoffrey; Pazdur, Richard

    2017-01-01

    Abstract Until recently in the United States, no products were approved for second‐line treatment of advanced urothelial carcinoma. On May 18, 2016, the U.S. Food and Drug Administration approved atezolizumab for the treatment of patients with locally advanced or metastatic urothelial carcinoma whose disease progressed during or following platinum‐containing chemotherapy or within 12 months of neoadjuvant or adjuvant treatment with platinum‐containing chemotherapy. Atezolizumab is a programmed death‐ligand 1 (PD‐L1) blocking antibody and represents the first approved product directed against PD‐L1. This accelerated approval was based on results of a single‐arm trial in 310 patients with locally advanced or metastatic urothelial carcinoma who had disease progression after prior platinum‐containing chemotherapy. Patients received atezolizumab 1,200 mg intravenously every 3 weeks until disease progression or unacceptable toxicity. Key efficacy measures were objective response rate (ORR), as assessed by Independent Review per RECIST 1.1, and duration of response (DoR). With a median follow‐up of 14.4 months, confirmed ORR was 14.8% (95% CI: 11.1, 19.3) in all treated patients. Median DoR was not reached and response durations ranged from 2.1+ to 13.8+ months. Of the 46 responders, 37 patients had an ongoing response for ≥ 6 months. The most common adverse reactions (≥20%) were fatigue, decreased appetite, nausea, urinary tract infection, pyrexia, and constipation. Infection and immune‐related adverse events also occurred, including pneumonitis, hepatitis, colitis, endocrine disorders, and rashes. Overall, the benefit‐risk assessment was favorable to support accelerated approval. The observed clinical benefits need to be verified in confirmatory trial(s). Implications for Practice. This accelerated approval of atezolizumab for second‐line use in advanced urothelial carcinoma provides patients with an effective, novel treatment option for the management of their disease. This represents the first immunotherapy approved in this disease setting. PMID:28424325

  6. 76 FR 37014 - Expedited Approval of Alternative Test Procedures for the Analysis of Contaminants Under the Safe...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-24

    ...; Analysis and Sampling Procedures AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY... Contaminants Under the Safe Drinking Water Act; Analysis and Sampling Procedures. 75 FR 32295. June 8, 2010...

  7. 76 FR 45573 - Record of Decision for the Final Environmental Impact Statement for Improvements to the Calexico...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-29

    ...: Notice. SUMMARY: Pursuant to the National Environmental Policy Act of 1969, the General Services... of Entry. On July 21, 2011, the Acting Regional Administrator, Pacific Rim Region, approved the ROD...

  8. Assumable Waters Subcommittee March 15-17, 2016, Meeting Summary

    EPA Pesticide Factsheets

    The purpose of the meeting was to provide advice and recommendations on how the EPA can best clarify which waters a State or Tribe assumes permitting responsibility for under an approved Clean Water Act section 404 program.

  9. 77 FR 8219 - Coastal Zone Management Program: Illinois

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-14

    ... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration Coastal Zone Management Program: Illinois AGENCY: Office of Ocean and Coastal Resource Management (OCRM), National Oceanic and... of Decision (ROD) for Federal Approval of the Illinois Coastal Management Program (ICMP). SUMMARY...

  10. 78 FR 71724 - Rail Depreciation Studies

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-29

    ... DEPARTMENT OF TRANSPORTATION Surface Transportation Board Rail Depreciation Studies AGENCY: Surface Transportation Board, DOT. ACTION: Notice of OMB Approval of Information Collection. SUMMARY... collection, Rail Depreciation Studies. See 78 FR 18676 (Mar. 27, 2013). This collection, codified at 49 CFR...

  11. 75 FR 25854 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-10

    ... 2060-0451 AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: In compliance with... Numbers: EPA ICR Number 1927.05, OMB Control Number 2060-0451. ICR Status: This ICR is scheduled to expire...

  12. 75 FR 5786 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-04

    ... 2060-0038 AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: In compliance with... 2060-0038. ICR Status: This ICR is scheduled to expire on March 31, 2010. Under OMB [[Page 5787...

  13. 75 FR 5638 - Information Collection Activities

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-03

    .... PHMSA-2009-0019 (Notice No. 09-7)] Information Collection Activities AGENCY: Pipeline and Hazardous Materials Safety Administration (PHMSA), DOT. ACTION: Notice of information collection approval. SUMMARY..., 2012, for the following information collection request (ICR): OMB Control No. 2137-0051, ``Rulemaking...

  14. Validation of source approval of HMA surface mix aggregate : research summary.

    DOT National Transportation Integrated Search

    2016-04-01

    Pavement surfaces must maintain an adequate level of friction in order to provide a : safe surface for vehicles. The Maryland State Highway Administration (SHA) is : responsible for ensuring that flexible pavement construction, using hot mix asphalt ...

  15. 75 FR 6337 - Approval and Promulgation of Air Quality Implementation Plans; Maryland; Control of Carbon...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-09

    ... Oxygen Furnaces AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA... basic oxygen furnaces (BOFs) at steel mills with a new CO standard for BOFs at steel mills. In the Final...

  16. Natural Gas Engine-Driven Heat Pump Demonstration at DoD Installations: Performance and Reliability Summary

    DTIC Science & Technology

    2009-06-09

    ER D C/ CE R L TR -0 9 -1 0 Natural Gas Engine-Driven Heat Pump Demonstration at DoD Installations Performance and Reliability Summary...L ab or at or y Approved for public release; distribution is unlimited. ERDC/CERL TR-09-10 June 2009 Natural Gas Engine-Driven Heat Pump ...CERL TR-09-10 ii Abstract: Results of field testing natural gas engine-driven heat pumps (GHP) at six southwestern U.S. Department of Defense (DoD

  17. Ada Compiler Validation Summary Report: Certificate Number: 891116W1.10194, Verdix Corporation, VADS VMS-MIL-STD-1750A, V6.0, MP, DEC MicroVAX III Host and Tektronix 1750A Emulator (Ethernet Download), v1.00-00 Target

    DTIC Science & Technology

    1989-11-16

    VRX Ada COMPILER VALIDATION SUMMARY REPORT; Certificate Number: 891116W1.10194 Verdix Corporation VADS VMS->MIL-STD-1750A, V6.0, MP DEC MicroVAX III...1.10 Customer Agreement Number: 89-08-30- VRX This report has been reviewed and i- approved. Ada Validation Facility Steven P. Wilson Technical

  18. A Study of the Effectiveness of the Army’s National Advertising Expenditures. Volume 1. Executive Summary.

    DTIC Science & Technology

    1981-08-31

    AD-A39 993 A STUDY OF THE EFFECTIVENESS OF THE RRMY’S NATIONAL 1/1 ADVERTISING EXPENDITURES VOLUME I EXECUTIVE SUNMARY(U) AYER (N W) INC NEW YORK 31... Advertising Expenditures ExecLtwe Summary N W AYER INCORPORATED :: ,AUGUST1981 DTIC OkEECTE Approved for Public Release 12 I’ Distribution Unlimited A...reverse side it necesary &-d Identify by block number) ADVERTISING , ACCESSIONS,* CONTRACTS, ACCESSIONS AS CONTRACTED, ARMY, RECRUITING, EFECTIVENESS

  19. Ensuring Biologics Advanced Development and Manufacturing Capability for the United States Government: A Summary of Key Findings and Conclusions

    DTIC Science & Technology

    2009-10-06

    Government: A Summary of Key Findings and Conclusions. This report has passed the Department of Defense’s security review process and is approved for...manufacturing and combine advance development and production of biologics in a multi-product facility focused on satisfying USG needs. Finally, the study...MCM needs of both DoD and HHS, an extensive survey was conducted. This included a review of all published requirements, the biodefense R&D portfolio

  20. Assumable Waters Subcommittee December 1-2, 2015, Meeting Summary

    EPA Pesticide Factsheets

    The purpose of the meeting was to continue the subcommittee's efforts to provide advice and recommendations on how EPA can clarify which waters a State or Tribe assumes permitting responsibility for under an approved Clean Water Act section 404 program.

  1. 76 FR 9777 - Recent Postings of Broadly Applicable Alternative Test Methods

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-22

    ... Applicable Alternative Test Methods AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of availability. SUMMARY: This notice announces the broadly applicable alternative test method approval decisions... technical questions about individual alternative test method decisions, refer to the contact person...

  2. 76 FR 5161 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-28

    ... FEDERAL HOUSING FINANCE AGENCY [No. 2011-N-02] Proposed Collection; Comment Request AGENCY: Federal Housing Finance Agency. ACTION: Submission of Information Collection for Emergency Approval from the Office of Management and Budget. SUMMARY: The Federal Housing Finance Agency (FHFA) submitted to...

  3. Antineoplastons (PDQ®)—Patient Version

    Cancer.gov

    Antineoplastons are derived from compounds found in urine and blood. Antineoplastons are not approved by the U.S. Food and Drug Administration for the prevention or treatment of any disease. Learn more about antineoplastons as a cancer treatment in this expert-reviewed summary.

  4. 75 FR 38532 - Medical Devices; Availability of Safety and Effectiveness Summaries for Premarket Approval...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-02

    ... LLIAC March 5, FDA-2010-M-0135 Scientific PREMOUNTED STENT SYSTEM 2010 Corp. P090006 Medtronic COMPLETE SE VASCULAR March 17, FDA-2010-M-0158 Vascular STENT SYSTEM 2010 II. Electronic Access Persons with...

  5. 78 FR 40096 - Information Collection Activity; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-03

    ... DEPARTMENT OF AGRICULTURE Rural Utilities Service Information Collection Activity; Comment Request AGENCY: Rural Utilities Service, USDA. ACTION: Notice and request for comments. SUMMARY: In accordance... Service (RUS) invites comments on this information collection for which approval from the Office of...

  6. 75 FR 8393 - Housing Counseling Training Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-24

    ... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5376-N-09] Housing Counseling Training Program AGENCY: Office of the Chief Information Officer, HUD. ACTION: Notice. SUMMARY: The proposed... following information: Title of Proposal: Housing Counseling Training Program. OMB Approval Number: 2502...

  7. 38 CFR 16.115 - IRB records.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... adequate documentation of IRB activities, including the following: (1) Copies of all research proposals reviewed, scientific evaluations, if any, that accompany the proposals, approved sample consent documents... basis for requiring changes in or disapproving research; and a written summary of the discussion of...

  8. 38 CFR 16.115 - IRB records.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... adequate documentation of IRB activities, including the following: (1) Copies of all research proposals reviewed, scientific evaluations, if any, that accompany the proposals, approved sample consent documents... basis for requiring changes in or disapproving research; and a written summary of the discussion of...

  9. 45 CFR 690.115 - IRB records.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... adequate documentation of IRB activities, including the following: (1) Copies of all research proposals reviewed, scientific evaluations, if any, that accompany the proposals, approved sample consent documents... basis for requiring changes in or disapproving research; and a written summary of the discussion of...

  10. 76 FR 67561 - Proposed Information Collection (VA Enrollment Certification) Activity: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-01

    ... educational benefits payable to claimants pursuing approved programs of education. DATES: Written comments and... Enrollment Certification) Activity: Comment Request AGENCY: Veterans Benefits Administration, Department of Veterans Affairs. ACTION: Notice. SUMMARY: The Veterans Benefits Administration (VBA), Department of...

  11. SMS design review summary report: Preliminary, NASA approval pending, type 1 data

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The minutes of Shuttle Mission Simulator (SMS) design review sessions are presented. Notes concerning design deficiencies of the SMS control panels are listed. The SMS power system, instructor/operator stations, and forward crew station are evalutated.

  12. Laetrile/Amygdalin (PDQ®)—Health Professional Version

    Cancer.gov

    Laetrile (Amygdalin) has shown little anticancer activity in animal studies and no anticancer activity in human clinical trials. Laetrile is not approved for use in the United States. Get detailed information about use of Laetrile for cancer in this summary for clinicians.

  13. Laetrile/Amygdalin (PDQ®)—Patient Version

    Cancer.gov

    Laetrile (Amygdalin) has shown little anticancer activity in animal studies and no anticancer activity in human clinical trials. Laetrile is not approved for use in the United States. Learn more about the use of Laetrile for cancer in this expert-reviewed summary.

  14. 77 FR 38062 - Proposed Agency Information Collection Activities; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-26

    ... FEDERAL MEDIATION AND CONCILIATION SERVICE Proposed Agency Information Collection Activities; Comment Request AGENCY: Federal Mediation and Conciliation Service. ACTION: Notice of request for renewal of previously approved collection form FMCS F-7. SUMMARY: The Federal Mediation and Conciliation...

  15. 77 FR 62433 - Hazard Communication Standard; Approval of Information Collection Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-15

    ... Information Collection Requirements AGENCY: Occupational Safety and Health Administration (OSHA), Labor... collection requirements. SUMMARY: The Occupational Safety and Health Administration (OSHA) is announcing that... DEPARTMENT OF LABOR Occupational Safety and Health Administration 29 CFR Parts 1910, 1915, and...

  16. 78 FR 25365 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-01

    ... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France... applies. FAA's Determination These helicopters have been approved by the aviation authority of France and...

  17. 76 FR 770 - Mendocino Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-06

    ... DEPARTMENT OF AGRICULTURE Forest Service Mendocino Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Mendocino County Resource Advisory Committee will meet January 21, 2011 (RAC) in Willits, California. Agenda items to be covered include: (1) Approval of...

  18. 75 FR 3197 - Mendocino Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-20

    ... DEPARTMENT OF AGRICULTURE Forest Service Mendocino Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Mendocino County Resource Advisory Committee will meet February 5, 2010 (RAC) in Willits, California. Agenda items to be covered include: (1) Approval of...

  19. 76 FR 16378 - Mendocino Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-23

    ... DEPARTMENT OF AGRICULTURE Forest Service Mendocino Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Mendocino County Resource Advisory Committee will meet April 15, 2011 (RAC) in Willits, California. Agenda items to be covered include: (1) Approval of...

  20. 77 FR 56607 - Mendocino Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-13

    ... DEPARTMENT OF AGRICULTURE Forest Service Mendocino Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Mendocino County Resource Advisory Committee will meet September 21, 2012 (RAC) in Willits, California. Agenda items to be covered include: (1) Approval...

  1. 75 FR 27704 - Mendocino Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-18

    ... DEPARTMENT OF AGRICULTURE Forest Service Mendocino Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Mendocino County Resource Advisory Committee will meet June 18, 2010 (RAC) in Willits, California. Agenda items to be covered include: (1) Approval of...

  2. 78 FR 77770 - Data Collection Available for Public Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-24

    ... SMALL BUSINESS ADMINISTRATION Data Collection Available for Public Comments ACTION: 60-day notice and request for comments SUMMARY: The Small Business Administration (SBA) intends to request approval... data. Title: U.S. Small Business Advisory Committee Membership--Nominee Information. Description of...

  3. 77 FR 59641 - Indian Gaming

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-28

    ... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming AGENCY: Bureau of Indian Affairs, Interior. ACTION: Notice of Deemed Approved Amended Tribal-State Class III Gaming Compact. SUMMARY: This.... FOR FURTHER INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian Gaming, Office of the...

  4. 75 FR 15431 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-29

    ... FEDERAL HOUSING FINANCE AGENCY [No. 2010-N-03] Proposed Collection; Comment Request AGENCY: Federal Housing Finance Agency. ACTION: 60-day notice of submission of information collection for approval from the Office of Management and Budget. SUMMARY: In accordance with the requirements of the Paperwork...

  5. 78 FR 39293 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-01

    ... FEDERAL HOUSING FINANCE AGENCY [No. 2013-N-10] Proposed Collection; Comment Request AGENCY: Federal Housing Finance Agency. ACTION: 60-day Notice of Submission of Information Collection for Approval from the Office of Management and Budget. SUMMARY: In accordance with the requirements of the Paperwork...

  6. 77 FR 76037 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-26

    ... FEDERAL HOUSING FINANCE AGENCY [No. 2012-N-19] Proposed Collection; Comment Request AGENCY: Federal Housing Finance Agency. ACTION: 60-day Notice of Submission of Information Collection for Approval from the Office of Management and Budget. SUMMARY: In accordance with the requirements of the Paperwork...

  7. 78 FR 39292 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-01

    ... FEDERAL HOUSING FINANCE AGENCY [No. 2013-N-09] Proposed Collection; Comment Request AGENCY: Federal Housing Finance Agency. ACTION: 60-day Notice of Submission of Information Collection for Approval From the Office of Management and Budget. SUMMARY: In accordance with the requirements of the Paperwork...

  8. 75 FR 40835 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-14

    ... FEDERAL HOUSING FINANCE AGENCY [No. 2010-N-09] Proposed Collection; Comment Request AGENCY: Federal Housing Finance Agency. ACTION: 30-day Notice of Submission of Information Collection for Approval from the Office of Management and Budget. SUMMARY: In accordance with the requirements of the Paperwork...

  9. 77 FR 65688 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-30

    ... FEDERAL HOUSING FINANCE AGENCY [No. 2012-N-15] Proposed Collection; Comment Request AGENCY: Federal Housing Finance Agency. ACTION: 30-Day notice of submission of information collection for approval from the Office of Management and Budget. SUMMARY: In accordance with the requirements of the Paperwork...

  10. 77 FR 46436 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-03

    ... FEDERAL HOUSING FINANCE AGENCY [No. 2012-N-08] Proposed Collection; Comment Request AGENCY: Federal Housing Finance Agency. ACTION: 60-day Notice of Submission of Information Collection for Approval from the Office of Management and Budget. SUMMARY: In accordance with the requirements of the Paperwork...

  11. 78 FR 63205 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-23

    ... FEDERAL HOUSING FINANCE AGENCY [No. 2013-N-13] Proposed Collection; Comment Request AGENCY: Federal Housing Finance Agency. ACTION: 30-day Notice of Submission of Information Collection for Approval from the Office of Management and Budget. SUMMARY: In accordance with the requirements of the Paperwork...

  12. 78 FR 13671 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-28

    ... FEDERAL HOUSING FINANCE AGENCY [No. 2013-N-02] Proposed Collection; Comment Request AGENCY: Federal Housing Finance Agency. ACTION: 30-day notice of submission of information collection for approval from the Office of Management and Budget. SUMMARY: In accordance with the requirements of the Paperwork...

  13. 77 FR 22316 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-13

    ... FEDERAL HOUSING FINANCE AGENCY [No. 2012-N-04] Proposed Collection; Comment Request AGENCY: Federal Housing Finance Agency. ACTION: 60-Day notice of submission of information collection for approval from Office of Management and Budget. SUMMARY: In accordance with the requirements of the Paperwork...

  14. 76 FR 53458 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-26

    ... FEDERAL HOUSING FINANCE AGENCY [No. 2011-N-09] Proposed Collection; Comment Request AGENCY: Federal Housing Finance Agency. ACTION: 30-day notice of submission of information collection for approval from the Office of Management and Budget. SUMMARY: In accordance with the Paperwork Reduction Act of...

  15. 76 FR 30344 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-25

    ... FEDERAL HOUSING FINANCE AGENCY [No. 2011-N-05] Proposed Collection; Comment Request AGENCY: Federal Housing Finance Agency. ACTION: 60-day notice of submission of information collection for approval from the Office of Management and Budget. SUMMARY: In accordance with the Paperwork Reduction Act of...

  16. 78 FR 16894 - Agency Information Collection Activities: Renewal of Currently Approved Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-19

    ... RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD Agency Information Collection Activities: Renewal... Management and Budget and 30- day public comment period. SUMMARY: The Recovery Accountability and... Recovery Accountability and Transparency Board, Office of Management and Budget, New Executive Office...

  17. Assumable Waters Subcommittee March 15-17, 2016, Meeting Summary

    EPA Pesticide Factsheets

    The purpose of this meeting was to begin to continue to develop advice and recommendations on how the EPA can best clarify which waters a State or Tribe assumes permitting responsibility for under an approved Clean Water Act (CWA) section 404 program.

  18. 78 FR 29426 - Agency Information Collection Activities: Requests for Comments; Clearance of Renewed Approval of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-20

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Agency Information Collection... Certification Standards for Subsonic Jet Airplanes and Subsonic Transport Category Large Airplanes AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice and request for comments. SUMMARY: In...

  19. 78 FR 48540 - Agency Information Collection Activities: Requests for Comments; Clearance of Renewed Approval of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-08

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Agency Information Collection... Certification Standards for Subsonic Jet Airplanes and Subsonic Transport Category Large Airplanes AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice and request for comments. SUMMARY: In...

  20. 76 FR 25379 - Proposed Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-04

    ... PEACE CORPS Proposed Information Collection ACTION: 60-Day notice and request for comments. SUMMARY: The Peace Corps will submit the following information collection request to the Office of... Peace Corps invites the general public to comment on this request for approval of reinstatement, without...

  1. 76 FR 61956 - Electronic Tariff Filing System (ETFS)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-06

    ...] Electronic Tariff Filing System (ETFS) AGENCY: Federal Communications Commission. ACTION: Final rule; announcement of effective date. SUMMARY: In this document, the Commission announces that the Office of Management and Budget (OMB) has approved, for a period of three years, the information collection associated...

  2. 78 FR 65871 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-04

    ... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France... aviation authority of France and are approved for operation in the United States. Pursuant to our bilateral...

  3. 77 FR 70360 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-26

    ... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for all Eurocopter France... France and are approved for operation in the United States. Pursuant to our bilateral agreement with...

  4. 78 FR 59306 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-26

    ...-0826; Directorate Identifier 2011-SW-046-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... helicopters have been approved by the aviation authority of France and [[Page 59307

  5. 75 FR 81287 - Mortgagee Review Board: Administrative Actions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-27

    ...: Administrative Actions AGENCY: Office of the Assistant Secretary for Housing--Federal Housing Commissioner, Department of Housing and Urban Development (HUD). ACTION: Notice. SUMMARY: In compliance with Section 202(c... actions taken by HUD's Mortgagee Review Board against HUD-approved mortgagees. FOR FURTHER INFORMATION...

  6. 75 FR 3479 - Mortgagee Review Board: Administrative Actions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ...: Administrative Actions AGENCY: Office of the Assistant Secretary for Housing-Federal Housing Commissioner, Department of Housing and Urban Development (HUD). ACTION: Notice. SUMMARY: In compliance with Section 202(c... actions taken by HUD's Mortgagee Review Board against HUD-approved mortgagees. FOR FURTHER INFORMATION...

  7. 77 FR 11149 - Mortgagee Review Board: Administrative Actions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-24

    ...: Administrative Actions AGENCY: Office of the Assistant Secretary for Housing--Federal Housing Commissioner, Department of Housing and Urban Development (HUD). ACTION: Notice. SUMMARY: In compliance with Section 202(c... actions taken by HUD's Mortgagee Review Board against HUD-approved mortgagees. FOR FURTHER INFORMATION...

  8. The Identification of Butyrylcholinesterase (BCHE) Polymorphisms in a Small Australian Defence Force Cohort

    DTIC Science & Technology

    2011-01-01

    Table D1: Summary of populations and number of individuals Population Approved individual DNA samples Approved Individual cell cultures Yoruba in...P65S Silent phenotype Protein expressed at low levels in culture . Poor activity 1-2% to BZ, BTC, ACT, PTA [11] rs75995351 N/A C373A F71L Unknown...codon at position 129 No protein expressed [8] BCHE*125F A619T L153F Silent phenotype Protein expressed at low levels in culture . Poor activity 1

  9. FDA: Evidentiary Standards for Drug Development and Approval

    PubMed Central

    Katz, Russell

    2004-01-01

    Summary: The United States Food and Drug Administration is charged with approving drug treatments that have been shown to be safe and effective. Relevant statutes and regulations provide a legal framework for establishing safety and effectiveness that is sufficiently flexible to ensure that appropriate scientific data are collected for specific treatments targeted to particular diseases. Nonetheless, all clinical trials proposed to establish effectiveness must incorporate common elements in order for the appropriate legal and scientific standards of drug approval to be met. This article will discuss the relevant laws and regulations pertaining to the current effectiveness standard and will discuss the most important clinical trial design elements currently considered acceptable for applications for treatments of neurologic and psychiatric illness. PMID:15717032

  10. Flipped script for gefitinib: A reapproved tyrosine kinase inhibitor for first-line treatment of epidermal growth factor receptor mutation positive metastatic nonsmall cell lung cancer.

    PubMed

    Bogdanowicz, Brian S; Hoch, Matthew A; Hartranft, Megan E

    2017-04-01

    Purpose The approval history, pharmacology, pharmacokinetics, clinical trials, efficacy, dosing recommendations, drug interactions, safety, place in therapy, and economic considerations of gefitinib are reviewed. Summary Lung cancer is one of the most commonly diagnosed cancers and is the leading cause of cancer death. Platinum-based chemotherapy and tyrosine kinase inhibitors, such as erlotinib and afatinib, are recommended therapies for nonsmall cell lung cancer. The European Medicines Association based their approval of gefitinib on the randomized, multicenter Iressa Pan-Asia Study (IPASS, NCT00322452) and a single-arm study showing effectiveness in Caucasians (IFUM, NCT01203917). Both studies were recently referenced by the United States Food & Drug Administration to reapprove gefitinib for the first-line treatment of advanced nonsmall cell lung cancer with epidermal growth factor receptor exon 19 deletions or exon 21 substitution. Diarrhea, acneiform rash, and interstitial lung disease are known side effects of gefitinib. Conclusion Use of gefitinib for the first-line therapy of metastatic nonsmall cell lung cancer with epidermal growth factor receptor exon 19 deletions (residues 747-750) or exon 21 substitution mutation (L858R) is well-documented and supported.

  11. 76 FR 7193 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-09

    ... purposes of collecting, validating, and verifying information, processing and maintaining information, and... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OECA-2010-0363; FRL-9265-1] Agency Information Collection... Processing Plants (Renewal) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: In...

  12. 77 FR 60160 - Submission for OMB Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-02

    ... OVERSEAS PRIVATE INVESTMENT CORPORATION Submission for OMB Review AGENCY: Overseas Private... notifying the public that the agency has prepared an information collection for OMB review and approval... Corporation, 1100 New York Avenue NW., Washington, DC 20527; (202) 336-8563. Summary Form Under Review Type of...

  13. 77 FR 41336 - Analytical Methods Used in Periodic Reporting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-13

    ... Methods Used in Periodic Reporting AGENCY: Postal Regulatory Commission. ACTION: Notice of filing. SUMMARY... proceeding to consider changes in analytical methods used in periodic reporting. This notice addresses... informal rulemaking proceeding to consider changes in the analytical methods approved for use in periodic...

  14. 77 FR 12089 - Proposed Generic Communication; Regulatory Issue Summary 2012-XX: Developing Inservice Testing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-28

    ... NUCLEAR REGULATORY COMMISSION [NRC-2012-0048] Proposed Generic Communication; Regulatory Issue... CFR) Part 52, ``Licenses, Certifications, and Approvals for Nuclear Power Plants,'' to satisfy the... inservice testing programs during the initial 120-month program interval following nuclear power plant...

  15. Guidelines for transportation program funds for eligible local projects : a summary of state and federal requirements

    DOT National Transportation Integrated Search

    2005-07-01

    This manual is intended for use by Local Public Agencies (LPA's) utilizing federal funds provided through the Nebraska Department of Roads (NDOR). The manual describes the process, documents, and approvals necessary for use of Federal Highway Adminis...

  16. 78 FR 65756 - Limitation on Claims Against Proposed Public Transportation Projects

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-01

    ... Public Transportation Projects AGENCY: Federal Transit Administration (FTA), DOT. ACTION: Notice. SUMMARY... review of the FTA actions announced herein for the listed public transportation project will be barred... taken final agency actions by issuing certain approvals for the public transportation project listed...

  17. 78 FR 45287 - Limitation on Claims against Proposed Public Transportation Projects

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-26

    ... Public Transportation Projects AGENCY: Federal Transit Administration (FTA), DOT. ACTION: Notice. SUMMARY... FTA action announced herein for the listed public transportation project will be barred unless the... final agency action by issuing a certain approval for the public transportation project listed below...

  18. 77 FR 35742 - Information Collection Available for Public Comments and Recommendations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-14

    ... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2012 0069] Information Collection Available for Public Comments and Recommendations ACTION: Notice of intention to request extension of OMB approval and request for comments. SUMMARY: In accordance with the Paperwork Reduction Act of...

  19. 78 FR 2439 - Agency Information Collection Activities: Proposed Collection; Comments Requested; Appeals of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-11

    ...] Agency Information Collection Activities: Proposed Collection; Comments Requested; Appeals of Background...., permitting electronic submission of responses. Summary of Information Collection (1) Type of Information Collection: Extension of a currently approved collection. (2) Title of the Form/Collection: Appeals of...

  20. 77 FR 43111 - Indian Gaming; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-23

    ... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Indian Gaming; Correction AGENCY: Bureau of Indian Affairs, Interior. ACTION: Notice of Approved Tribal--State Class III Gaming Compact; Correction. SUMMARY: The Bureau of Indian Affairs (BIA) published a document in the Federal Register of July 12, 2012...

  1. 75 FR 31744 - Information Collection; Contract Operations and Administration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-04

    ... Administration AGENCY: Forest Service, USDA. ACTION: Notice; request for comment. SUMMARY: In accordance with the... organizations on a new information collection, Contract Operations and Administration. DATES: Comments must be... INFORMATION: Title: Contract Operations and Administration. OMB Number: 0596-NEW. Expiration Date of Approval...

  2. High-Dose Vitamin C (PDQ®)—Patient Version

    Cancer.gov

    High-dose vitamin C, in some studies, has shown improved quality of life and fewer side effects in some cancer patients. The U.S. Food and Drug Administration has not approved its use as a treatment for cancer. Learn more in this expert-reviewed summary.

  3. 75 FR 57506 - Summary of Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-21

    ... indirect green goods and services, noting that examples such as USDA approved fertilizers, wind turbine... safety education and compliance related to environmental problems has a beneficial impact on the... health and worker health from the adverse effects of environmental problems. For the reason given in the...

  4. 7 CFR 1437.7 - Records.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... be provided no later than the acreage reporting date for the crop in the subsequent crop year... to calculate an approved yield for the current crop year must be certified by the producer no later...: (1) Commercial receipts, settlement sheets, warehouse ledger sheets, or load summaries if the...

  5. 7 CFR 1437.7 - Records.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... be provided no later than the acreage reporting date for the crop in the subsequent crop year... to calculate an approved yield for the current crop year must be certified by the producer no later...: (1) Commercial receipts, settlement sheets, warehouse ledger sheets, or load summaries if the...

  6. 7 CFR 1437.7 - Records.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... be provided no later than the acreage reporting date for the crop in the subsequent crop year... to calculate an approved yield for the current crop year must be certified by the producer no later...: (1) Commercial receipts, settlement sheets, warehouse ledger sheets, or load summaries if the...

  7. 7 CFR 1437.7 - Records.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... be provided no later than the acreage reporting date for the crop in the subsequent crop year... to calculate an approved yield for the current crop year must be certified by the producer no later...: (1) Commercial receipts, settlement sheets, warehouse ledger sheets, or load summaries if the...

  8. 7 CFR 1437.7 - Records.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... be provided no later than the acreage reporting date for the crop in the subsequent crop year... to calculate an approved yield for the current crop year must be certified by the producer no later...: (1) Commercial receipts, settlement sheets, warehouse ledger sheets, or load summaries if the...

  9. 21 CFR 56.115 - IRB records.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... research proposals reviewed, scientific evaluations, if any, that accompany the proposals, approved sample... abstaining; the basis for requiring changes in or disapproving research; and a written summary of the... this regulation shall be retained for at least 3 years after completion of the research, and the...

  10. 77 FR 38660 - Agency Information Collection Activities; Submission for OMB Review; Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-28

    ... for OMB Review; Comment Request; Rehabilitation Maintenance Certificate ACTION: Notice. SUMMARY: The... information collection request (ICR) revision titled, ``Rehabilitation Maintenance Certificate,'' to the Office of Management and Budget (OMB) for review and approval for use in accordance with the Paperwork...

  11. 78 FR 52925 - Agency Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-27

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Agency for Healthcare Research and Quality Agency... Research and Quality, HHS. ACTION: Notice. SUMMARY: This notice announces the intention of the Agency for Healthcare Research and Quality (AHRQ) to request that the Office of Management and Budget (OMB) approve the...

  12. Cannabis and Cannabinoids (PDQ®)—Health Professional Version

    Cancer.gov

    Cannabis has been used medicinally for millennia, but has not been approved by the U.S. Food and Drug Administration to treat any medical condition. Cannabinoids are the components in cannabis; some are commercially available to treat symptoms. Get detailed information in this clinician summary.

  13. 76 FR 77998 - Market Access Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-15

    ... FARM CREDIT ADMINISTRATION Market Access Agreement AGENCY: Farm Credit Administration. ACTION: Notice of approval of the Draft Second Amended and Restated Market Access Agreement. SUMMARY: The Farm... Access Agreement (Draft Second Restated MAA) proposed to be entered into by all of the banks of the Farm...

  14. 78 FR 7778 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-04

    ... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OPP-2010-0793; FRL-9527-3] Information Collection Request... Annual Measures Reporting AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: The Environmental Protection Agency has submitted an information collection request (ICR), ``Pesticide Environmental...

  15. 75 FR 39058 - Submission of Information Collection for OMB Review; Comment Request; Reconsideration of Initial...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-07

    ... PENSION BENEFIT GUARANTY CORPORATION Submission of Information Collection for OMB Review; Comment Request; Reconsideration of Initial Determinations AGENCY: Pension Benefit Guaranty Corporation. ACTION: Notice of request for extension of OMB approval. SUMMARY: The Pension Benefit Guaranty Corporation (PBGC...

  16. 75 FR 7295 - Submission of Information Collection for OMB Review; Comment Request; Administrative Appeals

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-18

    ... PENSION BENEFIT GUARANTY CORPORATION Submission of Information Collection for OMB Review; Comment Request; Administrative Appeals AGENCY: Pension Benefit Guaranty Corporation. ACTION: Notice of request for extension of OMB approval. SUMMARY: The Pension Benefit Guaranty Corporation (PBGC) is requesting...

  17. 78 FR 13712 - Submission of Information Collection for OMB Review; Comment Request; Administrative Appeals

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-28

    ... PENSION BENEFIT GUARANTY CORPORATION Submission of Information Collection for OMB Review; Comment Request; Administrative Appeals AGENCY: Pension Benefit Guaranty Corporation. ACTION: Notice of request for extension of OMB approval. SUMMARY: The Pension Benefit Guaranty Corporation (PBGC) is requesting...

  18. 76 FR 5220 - Submission of Information Collection for OMB Review; Comment Request; Multiemployer Plan Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-28

    ... PENSION BENEFIT GUARANTY CORPORATION Submission of Information Collection for OMB Review; Comment Request; Multiemployer Plan Regulations AGENCY: Pension Benefit Guaranty Corporation. ACTION: Notice of request for extension of OMB approval. SUMMARY: The Pension Benefit Guaranty Corporation (PBGC) is...

  19. 76 FR 22708 - Federal Acquisition Regulation; Information Collection; OMB Circular A-119

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-22

    ... previously approved information collection requirement concerning OMB Circular A-119. Public comments are...; Information Collection; OMB Circular A-119 AGENCIES: Department of Defense (DOD), General Services... public comments regarding an extension to an existing OMB clearance (9000-0153). SUMMARY: Under the...

  20. Connected Vehicle Pilot Deployment Program Phase 1, Human Use Approval Summary – ICF/Wyoming.

    DOT National Transportation Integrated Search

    2016-07-18

    The Wyoming Department of Transportations (WYDOT) Connected Vehicle (CV) Pilot Deployment Program is intended to develop a suite of applications that utilize vehicle to infrastructure (V2I) and vehicle to vehicle (V2V) communication technology to ...

  1. 75 FR 41877 - Insured Healthcare Facilities 232 Loan Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-19

    ... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5376-N-65] Insured Healthcare Facilities 232 Loan Application AGENCY: Office of the Chief Information Officer, HUD. ACTION: Notice. SUMMARY... Proposal: Insured Healthcare Facilities 232 Loan Application. OMB Approval Number: 2502-New. Form Numbers...

  2. 75 FR 16821 - Insured Healthcare Facilities 232 Loan Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-02

    ... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5376-N-23] Insured Healthcare Facilities 232 Loan Application AGENCY: Office of the Chief Information Officer, HUD. ACTION: Notice. SUMMARY...: Title of Proposal: Insured Healthcare Facilities 232 Loan Application. OMB Approval Number: 2502-New...

  3. 39 CFR 501.10 - Postage Evidencing System modifications.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... AND DISTRIBUTE POSTAGE EVIDENCING SYSTEMS § 501.10 Postage Evidencing System modifications. (a) An... 39 Postal Service 1 2010-07-01 2010-07-01 false Postage Evidencing System modifications. 501.10... a previously approved Postage Evidencing System. The notification must include a summary of all...

  4. 77 FR 72814 - Information Collection; Secure Rural Schools Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-06

    ... DEPARTMENT OF AGRICULTURE Forest Service Information Collection; Secure Rural Schools Act AGENCY: Forest Service, USDA. ACTION: Notice; request for comment. SUMMARY: In accordance with the Paperwork Reduction Act of 1995, this notice announces the intention of the Forest Service to seek approval to renew...

  5. 78 FR 9634 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-11

    ...-0119; Directorate Identifier 2011-SW-034-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... helicopter. FAA's Determination These helicopters have been approved by the aviation authority of France and...

  6. 78 FR 59298 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-26

    ...-1158; Directorate Identifier 2010-SW-018-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to revise airworthiness directive (AD) 2011-22-05 for Eurocopter France (Eurocopter...'s Determination These helicopters have been approved by the aviation authority of France and are...

  7. 78 FR 34700 - Data Collection Available for Public Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-10

    ... SMALL BUSINESS ADMINISTRATION Data Collection Available for Public Comments ACTION: 60-Day Notice and request for comments. SUMMARY: In accordance with the Paperwork Reduction Act of 1995, this notice announces the Small Business Administration's intentions to request approval on a new and/or currently...

  8. 78 FR 47813 - Data Collection Available for Public Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-06

    ... SMALL BUSINESS ADMINISTRATION Data Collection Available for Public Comments ACTION: 60 Day notice and request for comments. SUMMARY: In accordance with the Paperwork Reduction Act of 1995, this notice announces the Small Business Administration's intentions to request approval on a new and/or currently...

  9. 78 FR 54362 - Data Collection Available for Public Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-03

    ... SMALL BUSINESS ADMINISTRATION Data Collection Available for Public Comments ACTION: 60-day notice and request for comments. SUMMARY: The Small Business Administration (SBA) intends to request approval, from the Office of Management and Budget (OMB) for the collection of information described below. The...

  10. 78 FR 15402 - Data Collection Available for Public Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-11

    ... SMALL BUSINESS ADMINISTRATION Data Collection Available for Public Comments ACTION: 60 Day Notice and request for comments. SUMMARY: In accordance with the Paperwork Reduction Act of 1995, this notice announces the Small Business Administration's intentions to request approval on a new and/or currently...

  11. 78 FR 47814 - Data Collection Available for Public Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-06

    ... SMALL BUSINESS ADMINISTRATION Data Collection Available for Public Comments ACTION: 60 Day notice and request for comments. SUMMARY: In accordance with the Paperwork Reduction Act of 1995, this notice announces the Small Business Administration's intentions to request approval on a new and/or currently...

  12. 78 FR 47813 - Data Collection Available for Public Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-06

    ... SMALL BUSINESS ADMINISTRATION Data Collection Available for Public Comments ACTION: 60 Day Notice and request for comments. SUMMARY: In accordance with the Paperwork Reduction Act of 1995, this notice announces the Small Business Administration's intentions to request approval on a new and/or currently...

  13. 78 FR 76697 - Data Collection Available for Public Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-18

    ... SMALL BUSINESS ADMINISTRATION Data Collection Available for Public Comments ACTION: 60-Day notice and request for comments. SUMMARY: In accordance with the Paperwork Reduction Act of 1995, this notice announces the Small Business Administration's intentions to request approval on a new and/or currently...

  14. 78 FR 53816 - Data Collection Available for Public Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-30

    ... SMALL BUSINESS ADMINISTRATION Data Collection Available for Public Comments ACTION: 60-day notice and request for comments. SUMMARY: The Small Business Administration (SBA) intends to request approval, from the Office of Management and Budget (OMB) for the collection of information described below. The...

  15. 78 FR 2313 - Actions Taken at December 14, 2012, Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-10

    ... SUSQUEHANNA RIVER BASIN COMMISSION Actions Taken at December 14, 2012, Meeting AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: As part of its regular business meeting held on December 14, 2012, in Annapolis, Maryland, the Commission took the following actions: (1) Approved...

  16. 77 FR 66214 - Actions Taken at September 20, 2012, Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-02

    ... SUSQUEHANNA RIVER BASIN COMMISSION Actions Taken at September 20, 2012, Meeting AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: As part of its regular business meeting held on September 20, 2012, in Harrisburg, Pennsylvania, the Commission took the following actions: approved or...

  17. 78 FR 22938 - Actions Taken at March 21, 2013, Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-17

    ... SUSQUEHANNA RIVER BASIN COMMISSION Actions Taken at March 21, 2013, Meeting AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: As part of its regular business meeting held on March 21, 2013, in Harrisburg, Pennsylvania, the Commission took the following actions: (1) Approved...

  18. 75 FR 6341 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-09

    ... Horse Quarantine Facilities. OMB Control Number: 0579-0313. Summary of Collection: The Animal Health... in subpart C of part 93, on the importation of horses include requirements for the approval and establishment of permanent, privately owned horse quarantine facilities that are operated under APHIS...

  19. IGESS: a statistical approach to integrating individual-level genotype data and summary statistics in genome-wide association studies.

    PubMed

    Dai, Mingwei; Ming, Jingsi; Cai, Mingxuan; Liu, Jin; Yang, Can; Wan, Xiang; Xu, Zongben

    2017-09-15

    Results from genome-wide association studies (GWAS) suggest that a complex phenotype is often affected by many variants with small effects, known as 'polygenicity'. Tens of thousands of samples are often required to ensure statistical power of identifying these variants with small effects. However, it is often the case that a research group can only get approval for the access to individual-level genotype data with a limited sample size (e.g. a few hundreds or thousands). Meanwhile, summary statistics generated using single-variant-based analysis are becoming publicly available. The sample sizes associated with the summary statistics datasets are usually quite large. How to make the most efficient use of existing abundant data resources largely remains an open question. In this study, we propose a statistical approach, IGESS, to increasing statistical power of identifying risk variants and improving accuracy of risk prediction by i ntegrating individual level ge notype data and s ummary s tatistics. An efficient algorithm based on variational inference is developed to handle the genome-wide analysis. Through comprehensive simulation studies, we demonstrated the advantages of IGESS over the methods which take either individual-level data or summary statistics data as input. We applied IGESS to perform integrative analysis of Crohns Disease from WTCCC and summary statistics from other studies. IGESS was able to significantly increase the statistical power of identifying risk variants and improve the risk prediction accuracy from 63.2% ( ±0.4% ) to 69.4% ( ±0.1% ) using about 240 000 variants. The IGESS software is available at https://github.com/daviddaigithub/IGESS . zbxu@xjtu.edu.cn or xwan@comp.hkbu.edu.hk or eeyang@hkbu.edu.hk. Supplementary data are available at Bioinformatics online. © The Author (2017). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  20. Summary of safety and effectiveness data from FDA: a valuable source of information on the performance of global endometrial ablation devices.

    PubMed

    Cooper, Jay; Gimpelson, Richard J

    2004-04-01

    To provide an overview of the approved second-generation endometrial ablation technologies. Data from the FDA Summary of Safety and Effectiveness Data were compared for Thermachoice, HydroThermablator, Her Option and Novasure devices. At 12 months' follow-up, Novasure and HydroThermablator had the highest amenorrhea rates. Thermochoice and Novasure had the highest success rates at 12 months. Novasure had the lowest adverse event rates in the first 24 hours, between 24 hours and 2 weeks and between 2 weeks and 1 year of follow-up. Summary of Safety and Effectiveness Data, obtainable on the FDA Web site, offers objective data for comparing second-generation endometrial ablation technologies.

  1. 76 FR 38219 - Submission for OMB Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-29

    ... OVERSEAS PRIVATE INVESTMENT CORPORATION [OMB-3420-0011; OPIC-115] Submission for OMB Review AGENCY... OMB review and approval. {Comments were solicited in the 60 day notice, posted on [October 2, 2007..., DC 20527; (202) 336-8563. Summary Form Under Review Type of Request: Revised form. Title: Application...

  2. 77 FR 40613 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-10

    ... FEDERAL HOUSING FINANCE AGENCY [No. 2012-N-07] Submission for OMB Review; Comment Request AGENCY: Federal Housing Finance Agency. ACTION: 30-Day notice of submission of information collection for approval from the Office of Management and Budget. SUMMARY: In accordance with the requirements of the Paperwork...

  3. 77 FR 65687 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-30

    ... FEDERAL HOUSING FINANCE AGENCY [No. 2012-N-16] Submission for OMB Review; Comment Request AGENCY: Federal Housing Finance Agency. ACTION: 30-Day notice of submission of information collection for approval from the Office of Management and Budget. SUMMARY: In accordance with the requirements of the Paperwork...

  4. 76 FR 23337 - Record of Decision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-26

    ... Environmental Impact Statement for the Tamiami Trail Modifications: Next Steps Project. SUMMARY: Pursuant to 42... Decision (ROD) for the Final Environmental Impact Statement (FEIS) for the Tamiami Trail (U.S. Highway 41...) to construct modifications to U.S. Highway 41 (Tamiami Trail) that were approved in the 2008 Limited...

  5. 75 FR 69047 - Senior Executive Service: Membership of Performance Review Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-10

    ... AGENCY FOR INTERNATIONAL DEVELOPMENT Senior Executive Service: Membership of Performance Review Board ACTION: Notice. SUMMARY: This notice lists approved candidates who will comprise a standing roster for service on the Agency's 2010 and 2011 SES Performance Review Boards. The Agency will use this...

  6. 77 FR 76597 - Limitation on Claims against Proposed Public Transportation Projects

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-28

    ... Public Transportation Projects AGENCY: Federal Transit Administration (FTA), DOT. ACTION: Notice. SUMMARY... actions announced herein for the listed public transportation project will be barred unless the claim is... issuing certain approvals for the public transportation project listed below. The actions on this project...

  7. 77 FR 64586 - Limitation on Claims Against Proposed Public Transportation Projects

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-22

    ... Public Transportation Projects AGENCY: Federal Transit Administration (FTA), DOT. ACTION: Notice. SUMMARY... actions announced herein for the listed public transportation project will be barred unless the claim is... actions by issuing certain approvals for the public transportation projects listed below. The actions on...

  8. 77 FR 34122 - Limitation on Claims Against Proposed Public Transportation Projects

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-08

    ... Public Transportation Projects AGENCY: Federal Transit Administration (FTA), DOT. ACTION: Notice. SUMMARY... claim seeking judicial review of the FTA actions announced herein for the listed public transportation... given that FTA has taken final agency actions by issuing certain approvals for the public transportation...

  9. 77 FR 51106 - Limitation on Claims Against Proposed Public Transportation Projects

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-23

    ... Public Transportation Projects AGENCY: Federal Transit Administration (FTA), DOT. ACTION: Notice. SUMMARY... claim seeking judicial review of the FTA actions announced herein for the listed public transportation... given that FTA has taken final agency actions by issuing certain approvals for the public transportation...

  10. 77 FR 12526 - Revisions to the California State Implementation Plan, Antelope Valley Air Quality Management...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-01

    ... the California State Implementation Plan, Antelope Valley Air Quality Management District and Mojave Desert Quality Management District AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is proposing to approve revisions to the Antelope Valley Air Quality Management District...

  11. 78 FR 21582 - Revisions to the California State Implementation Plan, Butte County Air Quality Management...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-11

    ... the California State Implementation Plan, Butte County Air Quality Management District and Sacramento Metropolitan Air Quality Management District AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is proposing to approve revisions to the Butte County Air Quality Management...

  12. 77 FR 59240 - Projects Rescinded for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-26

    ... SUSQUEHANNA RIVER BASIN COMMISSION Projects Rescinded for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: This notice lists the projects rescinded by the... rescinded for the consumptive use of water pursuant to the Commission's approval by rule process set forth...

  13. 77 FR 55893 - Projects Rescinded for Consumptive Uses of Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-11

    ... SUSQUEHANNA RIVER BASIN COMMISSION Projects Rescinded for Consumptive Uses of Water AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: This notice lists the projects rescinded by the... the consumptive use of water pursuant to the Commission's approval by rule process set forth in 18 CFR...

  14. 78 FR 20912 - Clean Water Act: Availability of List Decisions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-08

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9798-8] Clean Water Act: Availability of List Decisions.... SUMMARY: The Clean Water Act requires that States periodically submit, and EPA approve or disapprove... are not stringent enough to attain or maintain State water quality standards and for which total...

  15. 77 FR 18246 - Agency Information Collection Request; 30-Day Public Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-27

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES [Document Identifier: OS-0990-0335; 30-Day Notice] Agency... of the Secretary (OS), Department of Health and Human Services, is publishing the following summary... OMB-approved program assessment requirements. The lack of general awareness and understanding about...

  16. 77 FR 4561 - Agency Information Collection Request; 60-Day Public Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-30

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES [Document Identifier: OS-0990-0335] Agency Information... Secretary (OS), Department of Health and Human Services, is publishing the following summary of a proposed... OMB-approved program assessment requirements. The lack of general awareness and understanding about...

  17. 77 FR 7576 - Farm, Ranch, and Rural Communities Committee (FRRCC)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-13

    ..., Ranch, and Rural Communities Committee (FRRCC). SUMMARY: The U.S. Environmental Protection Agency (EPA... approved by the Designated Federal Officer (DFO). Meetings will generally be held in Washington, DC... diverse candidates, EPA encourages nominations of women and men of all racial and ethnic groups. In...

  18. 77 FR 66793 - Senior Executive Service: Membership of Performance Review Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-07

    ... AGENCY FOR INTERNATIONAL DEVELOPMENT Senior Executive Service: Membership of Performance Review Board ACTION: Notice. SUMMARY: This notice lists approved candidates who will comprise a standing roster for service on the Agency's 2012 and 2013 SES Performance Review Boards. The Agency will use this...

  19. 76 FR 80360 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-23

    ..., Oceans and Coastal Protection Division, (4504T), Environmental Protection Agency, 1200 Pennsylvania Ave... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OW-2008-0150; FRL-9508-9] Agency Information Collection... Clean Water Act (Renewal) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: In...

  20. 76 FR 30202 - Notice of Intent To Seek Approval To Establish an Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-24

    ...In compliance with the requirement of Section 3506(c)(2)(A) of the Paperwork Reduction Act of 1995 for opportunity for public comment on proposed data collection projects, the National Science Foundation (NSF) will publish periodic summaries of proposed projects.

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