Scaled signal intensity of uterine fibroids based on T2-weighted MR images: a potential objective method to determine the suitability for magnetic resonance-guided focused ultrasound surgery of uterine fibroids.

PubMed

Park, Hyun; Yoon, Sang-Wook; Sokolov, Amit

2015-12-01

Magnetic Resonance-guided Focused Ultrasound Surgery (MRgFUS) is a non-invasive method to treat uterine fibroids. To help determine the patient suitability for MRgFUS, we propose a new objective measure: the scaled signal intensity (SSI) of uterine fibroids in T2 weighted MR images (T2WI). Forty three uterine fibroids in 40 premenopausal women were included in this retrospective study. SSI of each fibroid was measured from the screening T2WI by standardizing its mean signal intensity to a 0-100 scale, using reference intensities of rectus abdominis muscle (0) and subcutaneous fat (100). Correlation between the SSI and the non-perfused volume (NPV) ratio (a measure for treatment success) was calculated. Pre-treatment SSI showed a significant inverse-correlation with post treatment NPV ratio (p < 0.05). When dichotomizing NPV ratio at 45 %, the optimal cut off value of the SSI was found to be 16.0. A fibroid with SSI value 16.0 or less can be expected to have optimal responses. The SSI of uterine fibroids in T2WI can be suggested as an objective parameter to help in patient selection for MRgFUS. • Signal intensity of fibroid in MR images predicts treatment response to MRgFUS. • Signal intensity is standardized into scaled form using adjacent tissues as references. • Fibroids with SSI less than 16.0 are expected to have optimal responses.

Phoenix Telemetry Processor

NASA Technical Reports Server (NTRS)

Stanboli, Alice

2013-01-01

Phxtelemproc is a C/C++ based telemetry processing program that processes SFDU telemetry packets from the Telemetry Data System (TDS). It generates Experiment Data Records (EDRs) for several instruments including surface stereo imager (SSI); robotic arm camera (RAC); robotic arm (RA); microscopy, electrochemistry, and conductivity analyzer (MECA); and the optical microscope (OM). It processes both uncompressed and compressed telemetry, and incorporates unique subroutines for the following compression algorithms: JPEG Arithmetic, JPEG Huffman, Rice, LUT3, RA, and SX4. This program was in the critical path for the daily command cycle of the Phoenix mission. The products generated by this program were part of the RA commanding process, as well as the SSI, RAC, OM, and MECA image and science analysis process. Its output products were used to advance science of the near polar regions of Mars, and were used to prove that water is found in abundance there. Phxtelemproc is part of the MIPL (Multi-mission Image Processing Laboratory) system. This software produced Level 1 products used to analyze images returned by in situ spacecraft. It ultimately assisted in operations, planning, commanding, science, and outreach.

Prospective comparison among transient elastography, supersonic shear imaging, and ARFI imaging for predicting fibrosis in nonalcoholic fatty liver disease

PubMed Central

Joo, Sae Kyung; Woo, Hyunsik; Lee, Dong Hyeon; Jung, Yong Jin; Kim, Byeong Gwan; Lee, Kook Lae

2017-01-01

The diagnostic performance of supersonic shear imaging (SSI) in comparison with those of transient elastography (TE) and acoustic radiation force impulse imaging (ARFI) for staging fibrosis in nonalcoholic fatty liver disease (NAFLD) patients has not been fully assessed, especially in Asian populations with relatively lean NAFLD compared to white populations. Thus, we focused on comparing the diagnostic performances of TE, ARFI, and SSI for staging fibrosis in a head-to-head manner, and identifying the clinical, anthropometric, biochemical, and histological features which might affect liver stiffness measurement (LSM) in our prospective biopsy-proven NAFLD cohort. In this study, ninety-four patients with biopsy-proven NAFLD were included prospectively. Liver stiffness was measured using TE, SSI, and ARFI within 1 month of liver biopsy. The diagnostic performance for staging fibrosis was assessed using receiver operating characteristic (ROC) analysis. Anthropometric data were evaluated as covariates influencing LSM by regression analyses. Liver stiffness correlated with fibrosis stage (p < 0.05); the area under the ROC curve of TE (kPa), SSI (kPa), and ARFI (m/s) were as follows: 0.757, 0.759, and 0.657 for significant fibrosis and 0.870, 0.809, and 0.873 for advanced fibrosis. Anthropometric traits were significant confounders affecting SSI, while serum liver injury markers significantly confounded TE and ARFI. In conclusion, the LSM methods had similar diagnostic performance for staging fibrosis in patients with NAFLD. Pre-LSM anthropometric evaluation may help predict the reliability of SSI. PMID:29176844

The Implement of a Multi-layer Frozen Soil Scheme into SSiB3 and its Evaluation over Cold Regions

NASA Astrophysics Data System (ADS)

Li, Q.

2016-12-01

The SSiB3 is a biophysics-based model of land-atmosphere interactions and is designed for global and regional studies. It has three soil layers, three snow layers, as well as one vegetation layer. Soil moisture of the three soil layers, interception water store for the canopy, subsurface soil temperature, ground temperature, canopy temperature and snow water equivalent are all predicted based on the water and energy balance at canopy, soil and snow. SSiB3 substantially enhances the model's capability for cold season studies and produces reasonable results compared with observations. However, frozen soil processes are ignored in the SSiB3 and may have effects on the interannual variability of soil temperature and deep soil memory. A multi-layer comprehensive frozen soil scheme (FSM), which is developed for climate study has been implemented into the SSiB3 to describe soil heat transfer and water flow affected by frozen processed in soil. In the coupled SSiB3-FSM, both liquid water and ice content have been taken into account in the frozen soil hydrologic and thermal property parameterization. The maximum soil layer depth could reach 10 meters thick depending on land conditions. To better evaluate the models' performance, the coupled offline SSiB3-FSM and SSiB3 have been driven from 1948 to 1958 by the Princeton global meteorological data set, respectively. For the 10yrs run, the coupled SSiB3-FSM almost captures the features over different regions, especially cold regions. In order to analysis and compare the differences of SSIB3-FSM and SSIB3 in detail, monthly mean surface temperature for different regions are compared with CAMS data. The statistical results of surface skin temperature show that high latitude regions, Africa, Eastern Australia, and North American monsoon regions have been greatly improved in SSIB3-FSM. For the global statistics, the RMSE of the surface temperature simulated by SSiB3-FSM can be improved about 0.6K compared to SSiB3. In this study, the improvements in the coupled SSiB3-FSM have also been analyzed.

Diagnosis and Treatment of Vascular Surgery Related Infection

PubMed Central

Zhang, Yong-Gan; Guo, Xue-Li; Song, Yan; Miao, Chao-Feng; Zhang, Chuang; Chen, Ning-Heng

2015-01-01

Surgical site infection (SSI) is an important component of infections acquired from hospital. The most significant feature of vascular surgery different from other surgeries is frequent application of artificial grafts. Once SSI occurs after vascular operations with grafts, it might results in a serious disaster. Staphylococcus aureus and coagulase-negative Staphylococcus are the most common pathogenic bacteria for SSI after vascular surgery. Although SSI in vascular surgery often lacks of typical clinical characters, some clinical symptoms, laboratory data and certain imaging procedures may help to diagnose. In most cases of SSI after vascular procedures, the artificial grafts must be removed and sensitive antibiotics should be administered. However, for different cases, personalized management plan should be made depending on the severity and location of SSI. PMID:26628937

Comparison of ocean surface solar irradiance in the GLA General Circulation Model and satellite-based calculations

NASA Technical Reports Server (NTRS)

Chertock, Beth; Sud, Y. C.

1993-01-01

A global, 7-year satellite-based record of ocean surface solar irradiance (SSI) is used to assess the realism of ocean SSI simulated by the nine-layer Goddard Laboratory for Atmospheres (GLA) General Circulation Model (GCM). January and July climatologies of net SSI produced by the model are compared with corresponding satellite climatologies for the world oceans between 54 deg N and 54 deg S. This comparison of climatologies indicates areas of strengths and weaknesses in the GCM treatment of cloud-radiation interactions, the major source of model uncertainty. Realism of ocean SSI is also important for applications such as incorporating the GLA GCM into a coupled ocean-atmosphere GCM. The results show that the GLA GCM simulates too much SSI in the extratropics and too little in the tropics, especially in the summer hemisphere. These discrepancies reach magnitudes of 60 W/sq m and more. The discrepancies are particularly large in the July case off the western coast of North America. Positive and negative discrepancies in SSI are shown to be consistent with discrepancies in planetary albedo.

Corridor One:An Integrated Distance Visualization Enuronments for SSI+ASCI Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Christopher R. Johnson, Charles D. Hansen

2001-10-29

The goal of Corridor One: An Integrated Distance Visualization Environment for ASCI and SSI Application was to combine the forces of six leading edge laboratories working in the areas of visualization and distributed computing and high performance networking (Argonne National Laboratory, Lawrence Berkeley National Laboratory, Los Alamos National Laboratory, University of Illinois, University of Utah and Princeton University) to develop and deploy the most advanced integrated distance visualization environment for large-scale scientific visualization and demonstrate it on applications relevant to the DOE SSI and ASCI programs. The Corridor One team brought world class expertise in parallel rendering, deep image basedmore » rendering, immersive environment technology, large-format multi-projector wall based displays, volume and surface visualization algorithms, collaboration tools and streaming media technology, network protocols for image transmission, high-performance networking, quality of service technology and distributed computing middleware. Our strategy was to build on the very successful teams that produced the I-WAY, ''Computational Grids'' and CAVE technology and to add these to the teams that have developed the fastest parallel visualizations systems and the most widely used networking infrastructure for multicast and distributed media. Unfortunately, just as we were getting going on the Corridor One project, DOE cut the program after the first year. As such, our final report consists of our progress during year one of the grant.« less

Solar irradiance assessment in insular areas using Himawari-8 satellite images

NASA Astrophysics Data System (ADS)

Liandrat, O.; Cros, S.; Turpin, M.; Pineau, J. F.

2016-12-01

The high amount of surface solar irradiance (SSI) in the tropics is an advantage for a profitable PV production. It will allow many tropical islands to pursue their economic growth with a clean, affordable and locally produced energy. However, the local meteorological conditions induce a very high variability which is problematic for a safe and gainful injection into the power grid. This issue is even more critical in non-interconnected territories where network stability is an absolute necessity. Therefore, the injection of PV power is legally limited in some European oversea territories. In this context, intraday irradiance forecasting (several hours ahead) is particularly useful to mitigate the production variability by reducing the cost of power storage management. At this time scale, cloud cover evolves with a stochastic behaviour not properly represented in numerical weather prediction (NWP) models. Analysing cloud motion using images from geostationary meteorological satellites is a well-known alternative to forecasting SSI up to 6 hours ahead with a better accuracy than NWP models. In this study, we present and apply our satellite-based solar irradiance forecasting methods over two measurement sites located in the field of view of the satellite Himawari-8: Cocos (Keeling) Islands (Australia) and New Caledonia (France). In particular, we converted 4 months of images from Himawari-8 visible channel into cloud index maps. Then, we applied an algorithm computing a cloud motion vector field from a short sequence of consecutive images. Comparisons between forecasted SSI at 1 hour of time horizon and collocated pyranometric measurements show a relative RMSE between 20 and 27%. Error sources related to the tropic insular context (coastal area heterogeneity, sub-pixel scale orographic cloud appearance, convective situation…) are discussed at every implementation step for the different methods.

Iodine-122-labeled amphetamine derivative with potential for PET brain blood-flow studies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mathis, C.A.; Sargent, T. 3d.; Shulgin, A.T.

1985-11-01

The positron emitter SSI (t1/2 3.6 min) was collected from a xenon- SS/iodine- SS ( SSXe/ SSI) generator and incorporated into an amphetamine analog, 2,4-dimethoxy-N,N-dimethyl-5-( SSI)iodophenylisopropylamine (5-( SSI)-2,4-DNNA). The remote synthesis was achieved in 3 min with a 50% radioincorporation yield and a product radiopurity of greater than 98%. 5-( SSI)-2,4-DNNA was injected into a beagle dog and a brain section imaged with positron emission tomography (PET). The uptake and retention of 5-( SSI)-2,4-DNNA was compared to that of YSRb in the same animal. Dynamic PET activity data were obtained 0-20 min postinjection of 5-( SSI)-2,4-DNNA and showed rapid uptakemore » by brain and good cerebral/extracerebral tissue distinction. A whole-body scan of a dog was also obtained with 5-123I-2,4-DNNA showing uptake in brain, lung, and other body organs. The feasibility of incorporating SSI into an extracted brain perfusion agent for use with PET is demonstrated.« less

Active Volcanism on Io as Seen by Galileo SSI

USGS Publications Warehouse

McEwen, A.S.; Keszthelyi, L.; Geissler, P.; Simonelli, D.P.; Carr, M.H.; Johnson, T.V.; Klaasen, K.P.; Breneman, H.H.; Jones, T.J.; Kaufman, J.M.; Magee, K.P.; Senske, D.A.; Belton, M.J.S.; Schubert, G.

1998-01-01

Active volcanism on Io has been monitored during the nominal Galileo satellite tour from mid 1996 through late 1997. The Solid State Imaging (SSI) experiment was able to observe many manifestations of this active volcanism, including (1) changes in the color and albedo of the surface, (2) active airborne plumes, and (3) glowing vents seen in eclipse. About 30 large-scale (tens of kilometers) surface changes are obvious from comparison of the SSI images to those acquired by Voyager in 1979. These include new pyroclastic deposits of several colors, bright and dark flows, and caldera-floor materials. There have also been significant surface changes on Io during the Galileo mission itself, such as a new 400-km-diameter dark pyroclastic deposit around Pillan Patera. While these surface changes are impressive, the number of large-scale changes observed in the four months between the Voyager 1 and Voyager 2 flybys in 1979 suggested that over 17 years the cumulative changes would have been much more impressive. There are two reasons why this was not actually the case. First, it appears that the most widespread plume deposits are ephemeral and seem to disappear within a few years. Second, it appears that a large fraction of the volcanic activity is confined to repeated resurfacing of dark calderas and flow fields that cover only a few percent of Io's surface. The plume monitoring has revealed 10 active plumes, comparable to the 9 plumes observed by Voyager. One of these plumes was visible only in the first orbit and three became active in the later orbits. Only the Prometheus plume has been consistently active and easy to detect. Observations of the Pele plume have been particularly intriguing since it was detected only once by SSI, despite repeated attempts, but has been detected several times by the Hubble Space Telescope at 255 nm. Pele's plume is much taller (460 km) than during Voyager 1 (300 km) and much fainter at visible wavelengths. Prometheus-type plumes (50-150 km high, long-lived, associated with high-temperature hot spots) may result from silicate lava flows or shallow intrusions interacting with near-surface SO2. A major and surprising result is that ~30 of Io's volcanic vents glow in the dark at the short wavelengths of SSI. These are probably due to thermal emission from surfaces hotter than 700 K (with most hotter than 1000 K), well above the temperature of pure sulfur volcanism. Active silicate volcanism appears ubiquitous. There are also widespread diffuse glows seen in eclipse, related to the interaction of energetic particles with the atmosphere. These diffuse glows are closely associated with the most active volcanic vents, supporting suggestions that Io's atmopshere is dominated by volcanic outgassing. Globally, volcanic centers are rather evenly distributed. However, 14 of the 15 active plumes seen by Voyager and/or Galileo are within 30?? of the equator, and there are concentrations of glows seen in eclipse at both the sub- and antijovian points. These patterns might be related to asthenospheric tidal heating or tidal stresses. Io will continue to be observed during the Galileo Europa Mission, which will climax with two close flybys of Io in late 1999. ?? 1998 Academic Press.

Active Volcanism on Io as Seen by Galileo SSI

NASA Astrophysics Data System (ADS)

McEwen, Alfred S.; Keszthelyi, Laszlo; Geissler, Paul; Simonelli, Damon P.; Carr, Michael H.; Johnson, Torrence V.; Klaasen, Kenneth P.; Breneman, H. Herbert; Jones, Todd J.; Kaufman, James M.; Magee, Kari P.; Senske, David A.; Belton, Michael J. S.; Schubert, Gerald

1998-09-01

Active volcanism on Io has been monitored during the nominal Galileo satellite tour from mid 1996 through late 1997. The Solid State Imaging (SSI) experiment was able to observe many manifestations of this active volcanism, including (1) changes in the color and albedo of the surface, (2) active airborne plumes, and (3) glowing vents seen in eclipse. About 30 large-scale (tens of kilometers) surface changes are obvious from comparison of the SSI images to those acquired by Voyager in 1979. These include new pyroclastic deposits of several colors, bright and dark flows, and caldera-floor materials. There have also been significant surface changes on Io during the Galileo mission itself, such as a new 400-km-diameter dark pyroclastic deposit around Pillan Patera. While these surface changes are impressive, the number of large-scale changes observed in the four months between the Voyager 1 and Voyager 2 flybys in 1979 suggested that over 17 years the cumulative changes would have been much more impressive. There are two reasons why this was not actually the case. First, it appears that the most widespread plume deposits are ephemeral and seem to disappear within a few years. Second, it appears that a large fraction of the volcanic activity is confined to repeated resurfacing of dark calderas and flow fields that cover only a few percent of Io's surface. The plume monitoring has revealed 10 active plumes, comparable to the 9 plumes observed by Voyager. One of these plumes was visible only in the first orbit and three became active in the later orbits. Only the Prometheus plume has been consistently active and easy to detect. Observations of the Pele plume have been particularly intriguing since it was detected only once by SSI, despite repeated attempts, but has been detected several times by the Hubble Space Telescope at 255 nm. Pele's plume is much taller (460 km) than during Voyager 1 (300 km) and much fainter at visible wavelengths. Prometheus-type plumes (50-150 km high, long-lived, associated with high-temperature hot spots) may result from silicate lava flows or shallow intrusions interacting with near-surface SO2. A major and surprising result is that ∼30 of Io's volcanic vents glow in the dark at the short wavelengths of SSI. These are probably due to thermal emission from surfaces hotter than 700 K (with most hotter than 1000 K), well above the temperature of pure sulfur volcanism. Active silicate volcanism appears ubiquitous. There are also widespread diffuse glows seen in eclipse, related to the interaction of energetic particles with the atmosphere. These diffuse glows are closely associated with the most active volcanic vents, supporting suggestions that Io's atmopshere is dominated by volcanic outgassing. Globally, volcanic centers are rather evenly distributed. However, 14 of the 15 active plumes seen by Voyager and/or Galileo are within 30° of the equator, and there are concentrations of glows seen in eclipse at both the sub- and antijovian points. These patterns might be related to asthenospheric tidal heating or tidal stresses. Io will continue to be observed during the Galileo Europa Mission, which will climax with two close flybys of Io in late 1999.

Refinements to SSiB with an Emphasis on Snow-Physics: Evaluation and Validation Using GSWP and Valdai Data

NASA Technical Reports Server (NTRS)

Mocko, David M.; Sud, Y. C.

2000-01-01

Refinements to the snow-physics scheme of SSiB (Simplified Simple Biosphere Model) are described and evaluated. The upgrades include a partial redesign of the conceptual architecture to better simulate the diurnal temperature of the snow surface. For a deep snowpack, there are two separate prognostic temperature snow layers - the top layer responds to diurnal fluctuations in the surface forcing, while the deep layer exhibits a slowly varying response. In addition, the use of a very deep soil temperature and a treatment of snow aging with its influence on snow density is parameterized and evaluated. The upgraded snow scheme produces better timing of snow melt in GSWP-style simulations using ISLSCP Initiative I data for 1987-1988 in the Russian Wheat Belt region. To simulate more realistic runoff in regions with high orographic variability, additional improvements are made to SSiB's soil hydrology. These improvements include an orography-based surface runoff scheme as well as interaction with a water table below SSiB's three soil layers. The addition of these parameterizations further help to simulate more realistic runoff and accompanying prognostic soil moisture fields in the GSWP-style simulations. In intercomparisons of the performance of the new snow-physics SSiB with its earlier versions using an 18-year single-site dataset from Valdai Russia, the version of SSiB described in this paper again produces the earliest onset of snow melt. Soil moisture and deep soil temperatures also compare favorably with observations.

Paterae on Io: Volcanic Activity Observed by Galileo's NIMS and SSI

NASA Technical Reports Server (NTRS)

Lopes, Rosaly; Kamp, Lucas; Smythe, W. D.; Carlson, R.; Radebaugh, Jani; Gregg, Tracy K.

2003-01-01

Paterae are the most ubiquitous volcanic construct on Io s surface. Paterae are irregular craters, or complex craters with scalloped edges, interpreted as calderas or pit craters. Data from Galileo has shown that the activity of Ionian paterae is often confined to its interior and that generally lava flows are not seen spilling out over the edges. We use observations from Galileo s Near-Infrared Mapping Spectrometer (NIMS) to study the thermal emission from several Ionian paterae and compare them with images in visible wavelengths obtained by Galileo s Solid State Imaging System (SSI). Galileo s close fly-bys of Io from 1999 to 2001 have allowed NIMS to image the paterae at high spatial resolution (1-30 km pixel). At these scales, several of these features reveal greater thermal emission around the edges, which can be explained as the crust of a lava lake breaking up against the paterae walls. Comparisons with imaging data show that lower albedo areas (which are indicative of young lavas) coincide with higher thermal emission areas on NIMS data. Other paterae, however, show thermal emission and features in the visible that are more consistent with lava flows over a solid patera floor. Identifying eruption styles on Io is important for constraining eruption and interior models on Io.

Phoenix Magnetic Properties Experiments Using the Surface Stereo Imager and the MECA Microscopy Station

NASA Astrophysics Data System (ADS)

Madsen, M. B.; Drube, L.; Falkenberg, T. V.; Haspang, M. P.; Ellehoj, M.; Leer, K.; Olsen, L. D.; Goetz, W.; Hviid, S. F.; Gunnlaugsson, H. P.; Hecht, M. H.; Parrat, D.; Lemmon, M. T.; Morris, R. V.; Pike, T.; Sykulska, H.; Vijendran, S.; Britt, D.; Staufer, U.; Marshall, J.; Smith, P. H.

2008-12-01

Phoenix carries as part of its scientific payload a series of magnetic properties experiments designed to utilize onboard instruments for the investigation of airborne dust, air-fall samples stirred by the retro-rockets of the lander, and sampled surface and sub-surface material from the northern plains of Mars. One of the aims of these experiments on Phoenix is to investigate any possible differences between airborne dust and soils found on the northern plains from similar samples in the equatorial region of Mars. The magnetic properties experiments are designed to control the pattern of dust attracted to or accumulated on the surfaces to enable interpretation of these patterns in terms of certain magnetic properties of the dust forming the patterns. The Surface Stereo Imager (SSI) provides multi-spectral information about dust accumulated on three iSweep targets on the lander instrument deck. The iSweeps utilize built in permanent magnets and 6 different background colors for the dust compared to only 1 for the MER sweep magnet. Simultaneously these iSweep targets are used as in-situ radiometric calibration targets for the SSI. The visible/near-infrared spectra acquired so far are similar to typical Martian dust and soil spectra. Because of the multiple background colors of the iSweeps the effect of the translucence of thin dust layers can be estimated. High resolution images (4 micrometers/px) acquired by the Optical Microscope (OM) showed subtle differences between different soil samples in particle size distribution, color and morphology. Most samples contain (typically 50 micrometer) large, subrounded particles that are substantially magnetic. The colors of these particles range from red, brown to (almost) black. Based on results from the Mars Exploration Rovers, these dark particles are believed to be enriched in magnetite. Occasionally, also very bright, whitish particles were found on the magnet substrates, likely held by cohesion forces to the magnet surface and/or to other (magnetic) particles.

An image assessment study of image acceptability of the Galileo low gain antenna mission

NASA Technical Reports Server (NTRS)

Chuang, S. L.; Haines, R. F.; Grant, T.; Gold, Yaron; Cheung, Kar-Ming

1994-01-01

This paper describes a study conducted by NASA Ames Research Center (ARC) in collaboration with the Jet Propulsion Laboratory (JPL), Pasadena, California on the image acceptability of the Galileo Low Gain Antenna mission. The primary objective of the study is to determine the impact of the Integer Cosine Transform (ICT) compression algorithm on Galilean images of atmospheric bodies, moons, asteroids and Jupiter's rings. The approach involved fifteen volunteer subjects representing twelve institutions involved with the Galileo Solid State Imaging (SSI) experiment. Four different experiment specific quantization tables (q-table) and various compression stepsizes (q-factor) to achieve different compression ratios were used. It then determined the acceptability of the compressed monochromatic astronomical images as evaluated by Galileo SSI mission scientists. Fourteen different images were evaluated. Each observer viewed two versions of the same image side by side on a high resolution monitor, each was compressed using a different quantization stepsize. They were requested to select which image had the highest overall quality to support them in carrying out their visual evaluations of image content. Then they rated both images using a scale from one to five on its judged degree of usefulness. Up to four pre-selected types of images were presented with and without noise to each subject based upon results of a previously administered survey of their image preferences. Fourteen different images in seven image groups were studied. The results showed that: (1) acceptable compression ratios vary widely with the type of images; (2) noisy images detract greatly from image acceptability and acceptable compression ratios; and (3) atmospheric images of Jupiter seem to have higher compression ratios of 4 to 5 times that of some clear surface satellite images.

Galileo SSI Observations of Io During Orbits C30 I33

NASA Technical Reports Server (NTRS)

Keszthelyi, L.; Turtle, E.; McEwen, A.; Simonelli, D.; Geissler, P.; Williams, D.; Milazzo, M.; Radebaugh, J.; Jaeger, W.; Klaasen, K. P.

2002-01-01

New Galileo SSI imaging of Io from orbits C30 I33 will be presented. The aging Galileo spacecraft continues to produce spectacular new results, including the tallest volcanic plume yet found on Io. Additional information is contained in the original extended abstract.

Animation of 'Dodo' and 'Goldilocks' Trenches

NASA Technical Reports Server (NTRS)

2008-01-01

[figure removed for brevity, see original site] Click on image for animation

A pan and zoom animation of the informally named 'Dodo' (on left) and 'Goldilocks' (on right) trenches as seen by the Surface Stereo Imager (SSI) aboard NASA's Phoenix Mars Lander. This animation was based on conditions on the Martian surface on Sol 17 (June 11, 2008), the 17th Martian day of the mission. 'Baby Bear' is the name of the sample taken from 'Goldilocks' and delivered to the Thermal and Evolved-Gas Analyzer (TEGA) instrument.

The Phoenix Mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is by NASA's Jet Propulsion Laboratory, Pasadena, Calif. Spacecraft development is by Lockheed Martin Space Systems, Denver.

False Color Terrain Model of Phoenix Workspace

NASA Technical Reports Server (NTRS)

2008-01-01

This is a terrain model of Phoenix's Robotic Arm workspace. It has been color coded by depth with a lander model for context. The model has been derived using images from the depth perception feature from Phoenix's Surface Stereo Imager (SSI). Red indicates low-lying areas that appear to be troughs. Blue indicates higher areas that appear to be polygons.

The Phoenix Mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is by NASA's Jet Propulsion Laboratory, Pasadena, Calif. Spacecraft development is by Lockheed Martin Space Systems, Denver.

Differences of standard values of Supersonic shear imaging and ARFI technique - in vivo study of testicular tissue.

PubMed

Trottmann, M; Rübenthaler, J; Marcon, J; Stief, C G; Reiser, M F; Clevert, D A

2016-01-01

To investigate the difference of standard values of Supersonic shear imaging (SSI) and Acoustic Radiation Force Impulse (ARFI) technique in the evaluation of testicular tissue stiffness in vivo. 58 healthy male testes were examined using B-mode sonography and ARFI and SSI. B-mode sonography was performed in order to scan the testis for pathologies followed by performance of real-time elastography in three predefined areas (upper pole, central portion and lower pole) using the SuperSonic® Aixplorer ultrasound device (SuperSonic Imagine, Aix-en-Provence, France). Afterwards a second assessment of the same testicular regions by elastography followed using the ARFI technique of the Siemens Acuson 2000™ ultrasound device (Siemens Health Care, Germany). Values of shear wave velocity were described in m/s. Parameters of elastography techniques were compared using paired sample t-test. The values of SSI were all significantly higher in all measured areas compared to ARFI (p < 0.001 to p = 0.015). Quantitatively there was a higher mean SSI wave velocity value of 1,1 compared to 0.8 m/s measured by ARFI. SSI values are significantly higher than ARFI values when measuring the stiffness of testicular tissue and should only be compared with caution.

Development of a digital-micromirror-device-based multishot snapshot spectral imaging system.

PubMed

Wu, Yuehao; Mirza, Iftekhar O; Arce, Gonzalo R; Prather, Dennis W

2011-07-15

We report on the development of a digital-micromirror-device (DMD)-based multishot snapshot spectral imaging (DMD-SSI) system as an alternative to current piezostage-based multishot coded aperture snapshot spectral imager (CASSI) systems. In this system, a DMD is used to implement compressive sensing (CS) measurement patterns for reconstructing the spatial/spectral information of an imaging scene. Based on the CS measurement results, we demonstrated the concurrent reconstruction of 24 spectral images. The DMD-SSI system is versatile in nature as it can be used to implement independent CS measurement patterns in addition to spatially shifted patterns that piezostage-based systems can offer. © 2011 Optical Society of America

Analyzing the risk factors influencing surgical site infections: the site of environmental factors.

PubMed

Alfonso-Sanchez, Jose L; Martinez, Isabel M; Martín-Moreno, Jose M; González, Ricardo S; Botía, Francisco

2017-06-01

Addressing surgical site infection (SSI) is accomplished, in part, through studies that attempt to clarify the nature of many essential factors in the control of SSI. We sought to examine the link between multiple risk factors, including environmental factors, and SSI for prevention management. We conducted a longitudinal prospective study to identify SSIs in all patients who underwent interventions in 2014 in 8 selected hospitals on the Mediterranean coast of Spain. Risk factors related to the operating theatre included level of fungi and bacterial contamination, temperature and humidity, air renewal and differential air pressure. Patient-related variables included age, sex, comorbidity, nutrition level and transfusion. Other factors were antibiotic prophylaxis, electric versus manual shaving, American Society of Anaesthesiologists physical status classification, type of intervention, duration of the intervention and preoperative stay. Superficial SSI was most often associated with environmental factors, such as environmental contamination by fungi (from 2 colony-forming units) and bacteria as well as surface contamination. When there was no contamination in the operating room, no SSI was detected. Factors that determined deep and organ/space SSI were more often associated with patient characteristics (age, sex, transfusion, nasogastric feeding and nutrition, as measured by the level of albumin in the blood), type of intervention and preoperative stay. Antibiotic prophylaxis and shaving with electric razor were protective factors for both types of infection, whereas the duration of the intervention and the classification of the intervention as "dirty" were shared risk factors. Our results suggest the importance of environmental and surface contamination control to prevent SSI.

Phoenix's Lay of the Land

NASA Technical Reports Server (NTRS)

2008-01-01

This image from NASA's Phoenix Mars Lander shows the spacecraft's recent activity site as of the 23rd Martian day of the mission, or Sol 22 (June 16, 2008), after the spacecraft touched down on the Red Planet's northern polar plains. The mosaic was taken by the lander's Surface Stereo Imager (SSI). Parts of Phoenix can be seen in the foreground.

The first two trenches dug by the lander's Robotic Arm, called 'Dodo' and 'Goldilocks,' were enlarged on the 19th Martian day of the mission, or Sol 18 (June 12, 2008), to form one trench, dubbed 'Dodo-Goldilocks.' Scoops of material taken from those trenches are informally called 'Baby Bear' and 'Mama Bear.' Baby Bear was carried to Phoenix's Thermal and Evolved-Gas Analyzer, or TEGA, instrument for analysis, while Mama Bear was delivered to Phoenix's Microscopy, Electrochemistry and Conductivity Analyzer instrument suite, or MECA, for a closer look.

The color inset picture of the Dodo-Goldilocks trench, also taken with Phoenix's SSI, reveals white material thought to be ice.

More recently, on Sol 22 (June 16, 2008), Phoenix's Robotic Arm began digging a trench, dubbed 'Snow White,' in a patch of Martian soil near the center of a polygonal surface feature, nicknamed 'Cheshire Cat.' The 'dump pile' is located at the top of the trench, and has been dubbed 'Croquet Ground.' The digging site has been nicknamed 'Wonderland.'

The Snow White trench, seen here in an SSI image from Sol 22 (June 16, 2008) is about 2 centimeters (.8 inches) deep and 30 centimeters (12 inches) long. As of Sol 25 (June 19, 2008), the trench is 5 centimeters (2 inches deep) and the trench has been renamed 'Snow White 1,' as a second trench has been dug to its right and nicknamed 'Snow White 2.'

The Phoenix Mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is by NASA's Jet Propulsion Laboratory, Pasadena, Calif. Spacecraft development is by Lockheed Martin Space Systems, Denver.

Correlation between classical rheometry and supersonic shear wave imaging in blood clots.

PubMed

Bernal, Miguel; Gennisson, Jean-Luc; Flaud, Patrice; Tanter, Mickael

2013-11-01

The assessment of coagulating blood elasticity has gained importance as a result of several studies that have correlated it to cardiovascular pathologic conditions. In this study we use supersonic shear wave imaging (SSI) to measure viscoelastic properties of blood clots. At the same time, classical rheometry experiments were carried out on the same blood samples taken within the first few seconds of coagulation. Using SSI, phase velocities of the shear wave indicated increasing dispersion with time. In all cases, the frequency bandwidth of propagating shear waves changed from 20-50 Hz at the first few min of coagulation to around 300 Hz toward the end of experiments. Using the values of G' and G″ from the rheometry studies, the theoretical shear wave velocities were calculated and correlated with SSI measurements. Results of the two techniques were in very good agreement, confirming that SSI provides accurate measurements of viscoelastic properties as corroborated by conventional rheometric measurements. Copyright © 2013 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

Phase II Randomized Trial of Negative-Pressure Wound Therapy to Decrease Surgical Site Infection in Patients Undergoing Laparotomy for Gastrointestinal, Pancreatic, and Peritoneal Surface Malignancies

PubMed Central

Shen, Perry; Blackham, Aaron U; Lewis, Stacey; Clark, Clancy J; Howerton, Russell; Mogal, Harveshp D; Dodson, Rebecca M; Russell, Gregory B; Levine, Edward A

2017-01-01

BACKGROUND Surgical site infections (SSIs) remain a major source of morbidity and cost after resection of intra-abdominal malignancies. Negative-pressure wound therapy (NPWT) has been reported to significantly reduce SSIs when applied to the closed laparotomy incision. This article reports the results of a randomized clinical trial examining the effect of NPWT on SSI rates in surgical oncology patients with increased risk for infectious complications. STUDY DESIGN From 2012 to 2016, two hundred and sixty-five patients who underwent open resection of intra-abdominal neoplasms were stratified into 3 groups: gastrointestinal (n = 57), pancreas (n = 73), or peritoneal surface (n = 135) malignancy. They were randomized to receive NPWT or standard surgical dressing (SSD) applied to the incision from postoperative days 1 through 4. Primary outcomes of combined incisional (superficial and deep) SSI rates were assessed up to 30 days after surgery. RESULTS There were no significant differences in superficial SSIs (12.8% vs 12.9%; p > 0.99) or deep SSI (3.0% vs 3.0%; p > 0.99) rates between the SSD and NPWT groups, respectively. When stratified by type of surgery, there were still no differences in combined incisional SSI rates for gastrointestinal (25% vs 24%; p > 0.99), pancreas (22% vs 22%; p > 0.99), and peritoneal surface malignancy (9% vs 9%; p > 0.99) patients. When performing univariate and multivariate logistic regression analysis of demographic and operative factors for the development of combined incisional SSI, the only independent predictors were preoperative albumin (p = 0.0031) and type of operation (p = 0.018). CONCLUSIONS Use of NPWT did not significantly reduce incisional SSI rates in patients having open resection of gastrointestinal, pancreatic, or peritoneal surface malignancies. Based on these results, at this time NPWT cannot be recommended as a therapeutic intervention to decrease infectious complications in these patient populations. PMID:28088597

Two Highly-Complementary Future Instruments for Climate Studies

NASA Astrophysics Data System (ADS)

Kopp, Greg; Pilewskie, Peter

2017-04-01

Measurements of the total solar irradiance (TSI) provide the most accurate knowledge of the net energy powering the Earth's climate system and thus give the incoming side of the Earth's radiative energy balance. The spectral distribution of this radiant energy, the spectral solar irradiance (SSI), determines how that incoming energy interacts with different components of the Earth's coupled ocean-atmosphere-surface climate system. Spatially- and spectrally-resolved Earth-reflected measurements of this shortwave radiation indicate the relative amount of the incident sunlight that is absorbed by different spatial regions and ecosystems around the globe. Particularly if very accurate and acquired over sufficiently long periods of time, those outgoing radiance measurements can lead to improved quantification of and physical understandings of the local and global processes causing climate change. Two upcoming and very complementary missions provide these measurements. The soon-to-be-launched Total and Spectral Solar Irradiance Sensor (TSIS) acquires the solar-irradiance measurements, with the Total Irradiance Monitor (TIM) providing highly-accurate values of the TSI and the Spectral Irradiance Monitor (SIM) measuring the SSI. The recently-selected CLARREO Pathfinder (CPF) is a technology-demonstration mission that measures the solar-reflected radiation via spatially- and spectrally-resolved observations of Earth scenes from its HyperSpectral Imager for Climate Science (HySICS), a spaceflight version of a high-altitude balloon-flight imaging spectrometer that achieves high radiometric accuracies via in-flight cross-calibrations directly tied to the SSI. We give an overview of the TSIS and the CPF, describing their instruments, the high complementarity of their measurements and intended uncertainties, and their planned timelines and current status.

Optical Extinction Measurements of Laser Side-Scatter During Tropical Storm Colin

NASA Technical Reports Server (NTRS)

Lane, John E.; Kasparis, Takis; Metzger, Philip; Michaelides, Silas

2017-01-01

A side-scatter imaging (SSI) technique using a 447 nm, 500 mW laser and a Nikon D80 camera was tested at Kennedy Space Center, Florida during the passing of a rain band associated with Tropical Storm Colin. The June 6, 2016, 22:00 GMT rain event was intense but short-lived owing to the strong west-to-east advection of the rain band. An effort to validate the optical extinction measurement was conducted by setting up a line of three tipping rain gauges along an 80 m east-west path and below the laser beam. Differences between tipping bucket measurements were correlated to the extinction coefficient profile along the lasers path, as determined by the SSI measurement. In order to compare the tipping bucket to the optical extinction data, a Marshall-Palmer DSD model was assumed. Since this was a daytime event, the laser beam was difficult to detect in the camera images, pointing out an important limitation of SSI measurements: the practical limit of DSD density that can be effectively detected and analyzed under daylight conditions using this laser and camera, corresponds to a fairly moderate rainfall rate on the order of 20 mmh (night measurements achieve a much improved sensitivity). The SSI analysis model under test produced promising results, but in order to use the SSI method for routine meteorological studies, improvements to the math model will be required.

Snowmelt and Infiltration Deficiencies of SSiB and Their Resolution with a New Snow-Physics Scheme

NASA Technical Reports Server (NTRS)

Sud, Y. C.; Mocko, David M.

1999-01-01

A two-year 1987-1988 integration of SSiB forced with ISLSCP Initiative I surface data (as part of the Global Soil Wetness Project, GSWP, evaluation and intercomparison) produced generally realistic land surface fluxes and hydrology. Nevertheless, the evaluation also helped to identify some of the deficiencies of the current version of the Simplified Simple Biosphere (SSiB) model. The simulated snowmelt was delayed in most regions, along with excessive runoff and lack of an spring soil moisture recharge. The SSIB model had previously been noted to have a problem producing accurate soil moisture as compared to observations in the Russian snowmelt region. Similarly, various GSWP implementations of SSIB found deficiencies in this region of the simulated soil moisture and runoff as compared to other non-SSiB land-surface models (LSMs). The origin of these deficiencies was: 1) excessive cooling of the snow and ground, and 2) deep frozen soil disallowing snowmelt infiltration. The problem was most severe in regions that experience very cold winters. In SSiB, snow was treated as a unified layer with the first soil layer, causing soil and snow to cool together in the winter months, as opposed to snow cover acting as an insulator. In the spring season, a large amount of heat was required to thaw a hard frozen snow plus deep soil layers, delaying snowmelt and causing meltwater to become runoff over the frozen soil rather than infiltrate into it.

Dark Skies and Clouds Move in at Phoenix site

NASA Technical Reports Server (NTRS)

2008-01-01

Clouds of dust and ice swirl past the Surface Stereo Imager (SSI) camera on NASA's Phoenix Mars Lander in a series of images taken on the 132nd Martian day of the mission (Oct. 7, 2008). The images show the increase in storm activity and potential for snowfall.

The solar powered spacecraft was disabled by decreased light from heavy dust storms in the area a few weeks later. The last communication heard from the lander occurred on Nov. 2, 2008.

The Phoenix Mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is by NASA's Jet Propulsion Laboratory, Pasadena, Calif. Spacecraft development is by Lockheed Martin Space Systems, Denver.

Supersonic Shear Imaging Elastography in Skeletal Muscles: Relationship Between In Vivo and Synthetic Fiber Angles and Shear Modulus.

PubMed

Lima, Kelly; Rouffaud, Remi; Pereira, Wagner; Oliveira, Liliam F

2018-04-30

To verify a relationship between the pennation angle of synthetic fibers and muscle fibers with the shear modulus (μ) generated by Supersonic shear imaging (SSI) elastography and to compare the anisotropy of synthetic and in vivo pennate muscle fibers in the x 2 -x 3 plane (probe perpendicular to water surface or skin). First, the probe of Aixplorer ultrasound scanner (v.9, Supersonic Imagine, Aix-en-Provence, France) was placed in 2 positions (parallel [aligned] and transverse to the fibers) to test the anisotropy in the x 2 -x 3 plane. Subsequently, it was inclined (x 1 -x 3 plane) in relation to the fibers, forming 3 angles (18.25 °, 21.55 °, 36.86 °) for synthetic fibers and one (approximately 0 °) for muscle fibers. On the x 2 -x 3 plane, μ values of the synthetic and vastus lateralis fibers were significantly lower (P < .0001) at the transverse probe position than the longitudinal one. In the x 1 -x 3 plane, the μ values were significantly reduced (P < .0001) with the probe angle increasing, only for the synthetic fibers (approximately 0.90 kPa for each degree of pennation angle). The pennation angle was not related to the μ values generated by SSI elastography for the in vivo lateral head of the gastrocnemius and vastus lateralis muscles. However, a μ reduction with an angle increase in the synthetic fibers was observed. These findings contribute to increasing the applicability of SSI in distinct muscle architecture at normal or pathologic conditions. © 2018 by the American Institute of Ultrasound in Medicine.

Soil on Phoenix Deck

NASA Technical Reports Server (NTRS)

2008-01-01

This image, taken by the Surface Stereo Imager (SSI) of NASA's Phoenix Lander, shows Martian soil piled on top of the spacecraft's deck and some of its instruments. Visible in the upper-left portion of the image are several wet chemistry cells of the lander's Microscopy, Electrochemistry, and Conductivity Analyzer (MECA). The instrument on the lower right of the image is the Thermal and Evolved-Gas Analyzer. The excess sample delivered to the MECA's sample stage can be seen on the deck in the lower left portion of the image.

This image was taken on Martian day, or sol, 142, on Saturday, Oct. 19, 2008. Phoenix landed on Mars' northern plains on May 25, 2008.

The Phoenix Mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is by NASA's Jet Propulsion Laboratory, Pasadena, Calif. Spacecraft development is by Lockheed Martin Space Systems, Denver.

The diagnostic performance of shear wave elastography for malignant cervical lymph nodes: A systematic review and meta-analysis.

PubMed

Suh, Chong Hyun; Choi, Young Jun; Baek, Jung Hwan; Lee, Jeong Hyun

2017-01-01

To evaluate the diagnostic performance of shear wave elastography for malignant cervical lymph nodes. We searched the Ovid-MEDLINE and EMBASE databases for published studies regarding the use of shear wave elastography for diagnosing malignant cervical lymph nodes. The diagnostic performance of shear wave elastography was assessed using bivariate modelling and hierarchical summary receiver operating characteristic modelling. Meta-regression analysis and subgroup analysis according to acoustic radiation force impulse imaging (ARFI) and Supersonic shear imaging (SSI) were also performed. Eight eligible studies which included a total sample size of 481 patients with 647 cervical lymph nodes, were included. Shear wave elastography showed a summary sensitivity of 81 % (95 % CI: 72-88 %) and specificity of 85 % (95 % CI: 70-93 %). The results of meta-regression analysis revealed that the prevalence of malignant lymph nodes was a significant factor affecting study heterogeneity (p < .01). According to the subgroup analysis, the summary estimates of the sensitivity and specificity did not differ between ARFI and SSI (p = .93). Shear wave elastography is an acceptable imaging modality for diagnosing malignant cervical lymph nodes. We believe that both ARFI and SSI may have a complementary role for diagnosing malignant cervical lymph nodes. • Shear wave elastography is acceptable modality for diagnosing malignant cervical lymph nodes. • Shear wave elastography demonstrated summary sensitivity of 81 % and specificity of 85 %. • ARFI and SSI have complementary roles for diagnosing malignant cervical lymph nodes.

The final Galileo SSI observations of Io: Orbits G28-I33

USGS Publications Warehouse

Turtle, E.P.; Keszthelyi, L.P.; McEwen, A.S.; Radebaugh, J.; Milazzo, M.; Simonelli, D.P.; Geissler, P.; Williams, D.A.; Perry, J.; Jaeger, W.L.; Klaasen, K.P.; Breneman, H.H.; Denk, T.; Phillips, C.B.

2004-01-01

We present the observations of Io acquired by the Solid State Imaging (SSI) experiment during the Galileo Millennium Mission (GMM) and the strategy we used to plan the exploration of Io. Despite Galileo's tight restrictions on data volume and downlink capability and several spacecraft and camera anomalies due to the intense radiation close to Jupiter, there were many successful SSI observations during GMM. Four giant, high-latitude plumes, including the largest plume ever observed on Io, were documented over a period of eight months; only faint evidence of such plumes had been seen since the Voyager 2 encounter, despite monitoring by Galileo during the previous five years. Moreover, the source of one of the plumes was Tvashtar Catena, demonstrating that a single site can exhibit remarkably diverse eruption styles - from a curtain of lava fountains, to extensive surface flows, and finally a ??? 400 km high plume - over a relatively short period of time (??? 13 months between orbits 125 and G29). Despite this substantial activity, no evidence of any truly new volcanic center was seen during the six years of Galileo observations. The recent observations also revealed details of mass wasting processes acting on Io. Slumping and landsliding dominate and occur in close proximity to each other, demonstrating spatial variation in material properties over distances of several kilometers. However, despite the ubiquitous evidence for mass wasting, the rate of volcanic resurfacing seems to dominate; the floors of paterae in proximity to mountains are generally free of debris. Finally, the highest resolution observations obtained during Galileo's final encounters with Io provided further evidence for a wide diversity of surface processes at work on Io. ?? 2003 Elsevier Inc. All rights reserved.

Subjective evaluations of integer cosine transform compressed Galileo solid state imagery

NASA Technical Reports Server (NTRS)

Haines, Richard F.; Gold, Yaron; Grant, Terry; Chuang, Sherry

1994-01-01

This paper describes a study conducted for the Jet Propulsion Laboratory, Pasadena, California, using 15 evaluators from 12 institutions involved in the Galileo Solid State Imaging (SSI) experiment. The objective of the study was to determine the impact of integer cosine transform (ICT) compression using specially formulated quantization (q) tables and compression ratios on acceptability of the 800 x 800 x 8 monochromatic astronomical images as evaluated visually by Galileo SSI mission scientists. Fourteen different images in seven image groups were evaluated. Each evaluator viewed two versions of the same image side by side on a high-resolution monitor; each was compressed using a different q level. First the evaluators selected the image with the highest overall quality to support them in their visual evaluations of image content. Next they rated each image using a scale from one to five indicating its judged degree of usefulness. Up to four preselected types of images with and without noise were presented to each evaluator.

Frost seen on Snow White Trench

NASA Technical Reports Server (NTRS)

2008-01-01

The Surface Stereo Imager (SSI) on NASA's Phoenix Mars Lander took this shadow-enhanced false color image of the 'Snow White' trench, on the eastern end of Phoenix's digging area. The image was taken on Sol 144, or the 144th day of the mission, Oct. 20, 2008. Temperatures measured on Sol 151, the last day weather data were received, showed overnight lows of minus128 Fahrenheit (minus 89 Celsius) and day time highs in the minus 50 F (minus 46 C) range. The last communication from the spacecraft came on Nov. 2, 2008.

The Phoenix Mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is by NASA's Jet Propulsion Laboratory, Pasadena, Calif. Spacecraft development is by Lockheed Martin Space Systems, Denver.

Galileo SSI Observations of Volcanic Activity at Tvashtar Catena, Io

NASA Technical Reports Server (NTRS)

Milazzo, M. P.; Keszthely, L. P.; Radebaugh, J.; Davies, A. G.; Turtle, E. P.; Geissler, P.; Klaasen, K. P.; McEwen, A. S.

2005-01-01

Introduction: We report on the analysis of the Galileo SSI's observations of the volcanic activity at Tvashtar Catena, Io as discussed by Milazzo et al. Galileo's Solid State Imager (SSI) observed Tvashtar Catena (63 deg N, 120 deg W) four times between November 1999 and October 2001, providing a unique look at the distinctive high latitude volcanism on Io. The November 1999 observation spatially resolved, for the first time, an active extraterrestrial fissure eruption. The brightness temperature of the lavas at the November 1999 fissure eruption was 1300 K. The second observation (orbit I27, February 2000) showed a large (approx. 500 sq km) region with many, small spots of hot, active lava. The third observation was taken in conjunction with a Cassini observation in December 2000 and showed a Pele-like plume deposition ring, while the Cassini images revealed a 400 km high Pele-type plume above the Catena. The final Galileo SSI observation of Tvashtar was acquired in October 2001, and all obvious (to SSI) activity had ceased, although data from Galileo's Near Infrared Mapping Spectrometer (NIMS) indicated that there was still significant thermal emission from the Tvashtar region. We have concentrated on analyzing the style of eruption during orbit I27 (February 2000). Comparison with a lava flow cooling model indicates that the behavior of the Tvashtar eruption during I27 does not match that of "simple" advancing lava flows. Instead, it may be an active lava lake or a complex set of lava flows with episodic, overlapping (in time and space) eruptions.

Effect of scan quality on diagnostic accuracy of spectral-domain optical coherence tomography in glaucoma.

PubMed

Rao, Harsha L; Addepalli, Uday K; Yadav, Ravi K; Senthil, Sirisha; Choudhari, Nikhil S; Garudadri, Chandra S

2014-03-01

To evaluate the effect of scan quality on the diagnostic accuracies of optic nerve head (ONH), retinal nerve fiber layer (RNFL), and ganglion cell complex (GCC) parameters of spectral-domain optical coherence tomography (SD OCT) in glaucoma. Cross-sectional study. Two hundred fifty-two eyes of 183 control subjects (mean deviation [MD]: -1.84 dB) and 207 eyes of 159 glaucoma patients (MD: -7.31 dB) underwent ONH, RNFL, and GCC scanning with SD OCT. Scan quality of SD OCT images was based on signal strength index (SSI) values. Influence of SSI on diagnostic accuracy of SD OCT was evaluated by receiver operating characteristic (ROC) regression. Diagnostic accuracies of all SD OCT parameters were better when the SSI values were higher. This effect was statistically significant (P < .05) for ONH and RNFL but not for GCC parameters. In mild glaucoma (MD of -5 dB), area under ROC curve (AUC) for rim area, average RNFL thickness, and average GCC thickness parameters improved from 0.651, 0.678, and 0.726, respectively, at an SSI value of 30 to 0.873, 0.962, and 0.886, respectively, at an SSI of 70. AUCs of the same parameters in advanced glaucoma (MD of -15 dB) improved from 0.747, 0.890, and 0.873, respectively, at an SSI value of 30 to 0.922, 0.994, and 0.959, respectively, at an SSI of 70. Diagnostic accuracies of SD OCT parameters in glaucoma were significantly influenced by the scan quality even when the SSI values were within the manufacturer-recommended limits. These results should be considered while interpreting the SD OCT scans for glaucoma. Copyright © 2014 Elsevier Inc. All rights reserved.

High-Resolution Views of Io's Emakong Patera: Latest Galileo Imaging Results

NASA Technical Reports Server (NTRS)

Williams, D. A.; Keszthelyi, L. P.; Davies, A. G.; Greeley, R.; Head, J. W., III

2002-01-01

This presentation will discuss analyses of the latest Galileo SSI (solid state imaging) high-resolution images of the Emakong lava channels and flow field on Jupiter's moon Io. Additional information is contained in the original extended abstract.

Multiple tuned mass damper based vibration mitigation of offshore wind turbine considering soil-structure interaction

NASA Astrophysics Data System (ADS)

Hussan, Mosaruf; Sharmin, Faria; Kim, Dookie

2017-08-01

The dynamics of jacket supported offshore wind turbine (OWT) in earthquake environment is one of the progressing focuses in the renewable energy field. Soil-structure interaction (SSI) is a fundamental principle to analyze stability and safety of the structure. This study focuses on the performance of the multiple tuned mass damper (MTMD) in minimizing the dynamic responses of the structures objected to seismic loads combined with static wind and wave loads. Response surface methodology (RSM) has been applied to design the MTMD parameters. The analyses have been performed under two different boundary conditions: fixed base (without SSI) and flexible base (with SSI). Two vibration modes of the structure have been suppressed by multi-mode vibration control principle in both cases. The effectiveness of the MTMD in reducing the dynamic response of the structure is presented. The dynamic SSI plays an important role in the seismic behavior of the jacket supported OWT, especially resting on the soft soil deposit. Finally, it shows that excluding the SSI effect could be the reason of overestimating the MTMD performance.

The Localized Scleroderma Skin Severity Index and Physician Global Assessment of Disease Activity: A Work in Progress Toward Development of Localized Scleroderma Outcome Measures

PubMed Central

ARKACHAISRI, THASCHAWEE; VILAIYUK, SOAMARAT; LI, SUZANNE; O’NEIL, KATHLEEN M.; POPE, ELENA; HIGGINS, GLORIA C.; PUNARO, MARILYNN; RABINOVICH, EGLA C.; ROSENKRANZ, MARGALIT; KIETZ, DANIEL A.; ROSEN, PAUL; SPALDING, STEVEN J.; HENNON, TERESA R.; TOROK, KATHRYN S.; CASSIDY, ELAINE; MEDSGER, THOMAS A.

2013-01-01

Objective To develop and evaluate a Localized Scleroderma (LS) Skin Severity Index (LoSSI) and global assessments’ clinimetric property and effect on quality of life (QOL). Methods A 3-phase study was conducted. The first phase involved 15 patients with LS and 14 examiners who assessed LoSSI [surface area (SA), erythema (ER), skin thickness (ST), and new lesion/extension (N/E)] twice for inter/intrarater reliability. Patient global assessment of disease severity (PtGA-S) and Children’s Dermatology Life Quality Index (CDLQI) were collected for intrarater reliability evaluation. The second phase was aimed to develop clinical determinants for physician global assessment of disease activity (PhysGA-A) and to assess its content validity. The third phase involved 2 examiners assessing LoSSI and PhysGA-A on 27 patients. Effect of training on improving reliability/validity and sensitivity to change of the LoSSI and PhysGA-A was determined. Results Interrater reliability was excellent for ER [intraclass correlation coefficient (ICC) 0.71], ST (ICC 0.70), LoSSI (ICC 0.80), and PhysGA-A (ICC 0.90) but poor for SA (ICC 0.35); thus, LoSSI was modified to mLoSSI. Examiners’ experience did not affect the scores, but training/practice improved reliability. Intrarater reliability was excellent for ER, ST, and LoSSI (Spearman’s rho = 0.71–0.89) and moderate for SA. PtGA-S and CDLQI showed good intrarater agreement (ICC 0.63 and 0.80). mLoSSI correlated moderately with PhysGA-A and PtGA-S. Both mLoSSI and PhysGA-A were sensitive to change following therapy. Conclusion mLoSSI and PhysGA-A are reliable and valid tools for assessing LS disease severity and show high sensitivity to detect change over time. These tools are feasible for use in routine clinical practice. They should be considered for inclusion in a core set of LS outcome measures for clinical trials. PMID:19833758

Quantifying the Extremity of Windstorms for Regions Featuring Infrequent Events

NASA Astrophysics Data System (ADS)

Walz, M. A.; Leckebusch, G. C.; Kruschke, T.; Rust, H.; Ulbrich, U.

2017-12-01

This paper introduces the Distribution-Independent Storm Severity Index (DI-SSI). The DI-SSI represents an approach to quantify the severity of exceptional surface wind speeds of large scale windstorms that is complementary to the Storm Severity Index (SSI) introduced by Leckebusch et al. (2008). While the SSI approaches the extremeness of a storm from a meteorological and potential loss (impact) perspective, the DI-SSI defines the severity in a more climatological perspective. The idea is to assign equal index values to wind speeds of the same singularity (e.g. the 99th percentile) under consideration of the shape of the tail of the local wind speed climatology. Especially in regions at the edge of the classical storm track the DI-SSI shows more equitable severity estimates, e.g. for the extra-tropical cyclone Klaus. Here were compare the integral severity indices for several prominent windstorm in the European domain and discuss the advantages and disadvantages of the respective index. In order to compare the indices, their relation with the North Atlantic Oscillation (NAO) is studied, which is one of the main large scale drivers for the intensity of European windstorms. Additionally we can identify a significant relationship between the frequency and intensity of windstorms for large parts of the European domain.

Winds at the Phoenix Landing Site

NASA Astrophysics Data System (ADS)

Holstein-Rathlou, C.; Gunnlaugsson, H. P.; Taylor, P.; Lange, C.; Moores, J.; Lemmon, M.

2008-12-01

Local wind speeds and directions have been measured at the Phoenix landing site using the Telltale wind indicator. The Telltale is mounted on top of the meteorological mast at roughly 2 meters height above the surface. The Telltale is a mechanical anemometer consisting of a lightweight cylinder suspended by Kevlar fibers that are deflected under the action of wind. Images taken with the Surface Stereo Imager (SSI) of the Telltale deflection allows the wind speed and direction to be quantified. Winds aloft have been estimated using image series (10 images ~ 50 s apart) taken of the Zenith (Zenith Movies). In contrast enhanced images cloud like features are seen to move through the image field and give indication of directions and angular speed. Wind speeds depend on the height of where these features originate while directions are unambiguously determined. The wind data shows dominant wind directions and diurnal variations, likely caused by slope winds. Recent night time measurements show frost formation on the Telltale mirror. The results will be discussed in terms of global and slope wind modeling and the current calibration of the data is discussed. It will also be illustrated how wind data can aid in interpreting temperature fluctuations seen on the lander.

Supersonic shear imaging for the diagnosis of liver fibrosis and portal hypertension in liver diseases: a meta-analysis.

PubMed

Deng, Han; Qi, Xingshun; Zhang, Tiansong; Qi, Xiaolong; Yoshida, Eric M; Guo, Xiaozhong

2018-01-01

The meta-analysis aimed to summarize the technical success rate of supersonic shear imaging (SSI) and to evaluate the diagnostic performance of liver and spleen stiffness measurement (LSM and SSM) with SSI for the detection of liver fibrosis, portal hypertension, and gastroesophageal varices in liver diseases. PubMed, EMBASE, and Cochrane Library databases were searched. Technical success rate of SSI was pooled. Area under curve (AUC), sensitivity, and specificity with corresponding 95% confidence interval (CI) were calculated. Included studies regarding the diagnostic performance of SSI for liver fibrosis, portal hypertension, and esophageal varices numbered 28, 4, and 4 respectively. The pooled technical success rates of LSM and SSM were 95.3% and 75.5%, respectively. The AUC, sensitivity, and specificity of LSM/SSM for different stages of liver fibrosis were 0.85-0.94, 0.7-0.89, and 0.82-0.92, respectively. The AUC, sensitivity, and specificity of LSM were 0.84 (95%CI = 0.8-0.86), 0.79 (95%CI = 0.7-0.85), and 0.82 (95%CI = 0.72-0.88) for clinically significant portal hypertension, 0.85 (95%CI = 0.82-0.88), 0.8 (95%CI = 0.68-0.88), and 0.8 (95%CI = 0.6-0.92) for any varices, and 0.86 (95%CI = 0.83-0.89), 0.86 (95%CI = 0.76-0.92), and 0.61 (95%CI = 0.35-0.83) for high-risk varices, respectively. LSM with SSI had a high diagnostic accuracy for liver fibrosis, but a moderate diagnostic accuracy for portal hypertension and esophageal varices.

Europa Stunning Surface

NASA Image and Video Library

2014-11-21

The puzzling, fascinating surface of Jupiter icy moon Europa looms large in this newly-reprocessed [sic] color view, made from images taken by NASA Galileo spacecraft in the late 1990s. This is the color view of Europa from Galileo that shows the largest portion of the moon's surface at the highest resolution. The view was previously released as a mosaic with lower resolution and strongly enhanced color (see PIA02590). To create this new version, the images were assembled into a realistic color view of the surface that approximates how Europa would appear to the human eye. The scene shows the stunning diversity of Europa's surface geology. Long, linear cracks and ridges crisscross the surface, interrupted by regions of disrupted terrain where the surface ice crust has been broken up and re-frozen into new patterns. Color variations across the surface are associated with differences in geologic feature type and location. For example, areas that appear blue or white contain relatively pure water ice, while reddish and brownish areas include non-ice components in higher concentrations. The polar regions, visible at the left and right of this view, are noticeably bluer than the more equatorial latitudes, which look more white. This color variation is thought to be due to differences in ice grain size in the two locations. Images taken through near-infrared, green and violet filters have been combined to produce this view. The images have been corrected for light scattered outside of the image, to provide a color correction that is calibrated by wavelength. Gaps in the images have been filled with simulated color based on the color of nearby surface areas with similar terrain types. This global color view consists of images acquired by the Galileo Solid-State Imaging (SSI) experiment on the spacecraft's first and fourteenth orbits through the Jupiter system, in 1995 and 1998, respectively. Image scale is 1 mile (1.6 kilometers) per pixel. North on Europa is at right. http://photojournal.jpl.nasa.gov/catalog/PIA19048

Martian Arctic Landscape Panorama Video

NASA Technical Reports Server (NTRS)

2008-01-01

[figure removed for brevity, see original site] Click on image for animation

Typical view if you were standing on Mars and slowly turned around for a look. Starting at the north, SSI sees its shadow and turns its head viewing solar arrays, the lander deck and landscape. Note very few rocks on the hummocky terrain and network of troughs, typical of polar surfaces here on Earth.

The Phoenix Mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is by NASA's Jet Propulsion Laboratory, Pasadena, Calif. Spacecraft development is by Lockheed Martin Space Systems, Denver.

Recent variability of the solar spectral irradiance and its impact on climate modelling

NASA Astrophysics Data System (ADS)

Ermolli, I.; Matthes, K.; Dudok de Wit, T.; Krivova, N. A.; Tourpali, K.; Weber, M.; Unruh, Y. C.; Gray, L.; Langematz, U.; Pilewskie, P.; Rozanov, E.; Schmutz, W.; Shapiro, A.; Solanki, S. K.; Woods, T. N.

2013-04-01

The lack of long and reliable time series of solar spectral irradiance (SSI) measurements makes an accurate quantification of solar contributions to recent climate change difficult. Whereas earlier SSI observations and models provided a qualitatively consistent picture of the SSI variability, recent measurements by the SORCE (SOlar Radiation and Climate Experiment) satellite suggest a significantly stronger variability in the ultraviolet (UV) spectral range and changes in the visible and near-infrared (NIR) bands in anti-phase with the solar cycle. A number of recent chemistry-climate model (CCM) simulations have shown that this might have significant implications on the Earth's atmosphere. Motivated by these results, we summarize here our current knowledge of SSI variability and its impact on Earth's climate. We present a detailed overview of existing SSI measurements and provide thorough comparison of models available to date. SSI changes influence the Earth's atmosphere, both directly, through changes in shortwave (SW) heating and therefore, temperature and ozone distributions in the stratosphere, and indirectly, through dynamical feedbacks. We investigate these direct and indirect effects using several state-of-the art CCM simulations forced with measured and modelled SSI changes. A unique asset of this study is the use of a common comprehensive approach for an issue that is usually addressed separately by different communities. We show that the SORCE measurements are difficult to reconcile with earlier observations and with SSI models. Of the five SSI models discussed here, specifically NRLSSI (Naval Research Laboratory Solar Spectral Irradiance), SATIRE-S (Spectral And Total Irradiance REconstructions for the Satellite era), COSI (COde for Solar Irradiance), SRPM (Solar Radiation Physical Modelling), and OAR (Osservatorio Astronomico di Roma), only one shows a behaviour of the UV and visible irradiance qualitatively resembling that of the recent SORCE measurements. However, the integral of the SSI computed with this model over the entire spectral range does not reproduce the measured cyclical changes of the total solar irradiance, which is an essential requisite for realistic evaluations of solar effects on the Earth's climate in CCMs. We show that within the range provided by the recent SSI observations and semi-empirical models discussed here, the NRLSSI model and SORCE observations represent the lower and upper limits in the magnitude of the SSI solar cycle variation. The results of the CCM simulations, forced with the SSI solar cycle variations estimated from the NRLSSI model and from SORCE measurements, show that the direct solar response in the stratosphere is larger for the SORCE than for the NRLSSI data. Correspondingly, larger UV forcing also leads to a larger surface response. Finally, we discuss the reliability of the available data and we propose additional coordinated work, first to build composite SSI data sets out of scattered observations and to refine current SSI models, and second, to run coordinated CCM experiments.

Data analysis for GOPEX image frames

NASA Technical Reports Server (NTRS)

Levine, B. M.; Shaik, K. S.; Yan, T.-Y.

1993-01-01

The data analysis based on the image frames received at the Solid State Imaging (SSI) camera of the Galileo Optical Experiment (GOPEX) demonstration conducted between 9-16 Dec. 1992 is described. Laser uplink was successfully established between the ground and the Galileo spacecraft during its second Earth-gravity-assist phase in December 1992. SSI camera frames were acquired which contained images of detected laser pulses transmitted from the Table Mountain Facility (TMF), Wrightwood, California, and the Starfire Optical Range (SOR), Albuquerque, New Mexico. Laser pulse data were processed using standard image-processing techniques at the Multimission Image Processing Laboratory (MIPL) for preliminary pulse identification and to produce public release images. Subsequent image analysis corrected for background noise to measure received pulse intensities. Data were plotted to obtain histograms on a daily basis and were then compared with theoretical results derived from applicable weak-turbulence and strong-turbulence considerations. Processing steps are described and the theories are compared with the experimental results. Quantitative agreement was found in both turbulence regimes, and better agreement would have been found, given more received laser pulses. Future experiments should consider methods to reliably measure low-intensity pulses, and through experimental planning to geometrically locate pulse positions with greater certainty.

View of Callisto at Increasing Resolutions

NASA Technical Reports Server (NTRS)

1998-01-01

These four views of Jupiter's second largest moon, Callisto, highlight how increasing resolutions enable interpretation of the surface. In the global view (top left) the surface is seen to have many small bright spots, while the regional view (top right) reveals the spots to be the larger craters. The local view (bottom right) not only brings out smaller craters and detailed structure of larger craters, but also shows a smooth dark layer of material that appears to cover much of the surface. The close-up frame (bottom left) presents a surprising smoothness in this highest resolution (30 meters per picture element) view of Callisto's surface.

North is to the top of these frames which were taken by the Solid State Imaging (SSI) system on NASA's Galileo spacecraft between November 1996 and November 1997. Even higher resolution images (better than 20 meters per picture element) of Callisto will be taken on June 30, 1999 during the 21st orbit of the spacecraft around Jupiter.

The top left frame is scaled to 10 kilometers (km) per picture element (pixel) and covers an area about 4400 by 2500 km. The moon Callisto, which has a diameter of 4806 km, appears to be peppered with many bright spots. Images at this resolution of other cratered moons in the Solar System indicate that the bright spots could be impact craters. The ring structure of Valhalla, the largest impact structure on Callisto, is visible in the center of the frame. This color view combines images obtained in November 1997 taken through the green, violet, and 1 micrometer filters of the SSI system.

The top right frame is ten times higher resolution (about 1 km per pixel) and covers an area approximately 440 by 250 km. Craters, which are clearly recognizable, appear to be the dominant landform on Callisto. The crater rims appear bright, while the adjacent area and the crater interiors are dark. This resolution is comparable to the best data available from the 1979 flyby's of NASA's two Voyager spacecraft; it reflects the understanding of Callisto prior to new data from Galileo. This Galileo image was taken in November 1996.

The resolution of the bottom right image is again ten times better (100 meters per pixel) and covering an area of about 44 by 25 km. This resolution reveals that some crater rims are not complete rings, but are composed of bright isolated segments. Steep slopes near crater rims reveal dark material that appears to have slid down to reveal bright material. The thickness of the dark layer could be tens of meters. The image was taken in June 1997.

The bottom left image at about 29 meters per pixel is the highest resolution available for Callisto. It covers an area about 4.4 by 2.5 km and is somewhat oblique. Craters are visible but no longer dominate the surface. The image was taken in November 1996.

The Jet Propulsion Laboratory, Pasadena, CA manages the Galileo mission for NASA's Office of Space Science, Washington, DC. JPL is an operating division of California Institute of Technology (Caltech).

This image and other images and data received from Galileo are posted on the World Wide Web, on the Galileo mission home page at URL http://galileo.jpl.nasa.gov. Background information and educational context for the images can be found at URL http://www.jpl.nasa.gov/galileo/sepo

NASA Spacecraft Sees 'Pac-Man' on Saturn Moon

NASA Image and Video Library

2017-12-08

NASA release date March 29, 2010 The highest-resolution-yet temperature map and images of Saturn’s icy moon Mimas obtained by NASA’s Cassini spacecraft reveal surprising patterns on the surface of the small moon, including unexpected hot regions that resemble “Pac-Man” eating a dot, and striking bands of light and dark in crater walls. The left portion of this image shows Mimas in visible light, an image that has drawn comparisons to the "Star Wars" Death Star. The right portion shows the new temperature map, which resembles 1980s video game icon "Pac Man." To learn more about this image go to: www.nasa.gov/centers/goddard/news/features/2010/pac-man-m... Credit: NASA/JPL/Goddard/SWRI/SSI NASA Goddard Space Flight Center is home to the nation's largest organization of combined scientists, engineers and technologists that build spacecraft, instruments and new technology to study the Earth, the sun, our solar system, and the universe.

Studies for the Loss of Atomic and Molecular Species from Io

NASA Technical Reports Server (NTRS)

Smyth, William H.

1999-01-01

A summary discussion of research undertaken in this project is presented and is related to six published papers attached in the appendix. The discussion is divided into six sections describing a variety of studies for the loss of atomic and molecular species from Io. They include studies for: (1) atomic sodium, (2) SO2, (3) O and S, (4) spectacular high-spatial resolution ultraviolet image observations of O, S, and possibly H in Io's atmosphere and/or corona acquired by the Space Telescope Imaging Spectrometer (STIS) of the Hubble Space Telescope (HST), (5) spectacular high-spatial resolution visible Io eclipse image observations acquired by the Solid State Imager (SSI) of Galileo spacecraft, (6) ground-based observations acquired by the Solid State Imager (SSI) of Galileo spacecraft, and (7) ground-based observations of Io's neutral cloud in [OI] 6300 angstrom emission. New source rates at Io's exobase for SO2, O, and H are given and a variety of interesting implications for Io's atmosphere and for the Io plasma torus are discussed. Appendices that are comprised of articles published during the contract are also presented.

Use of midlatitude soil moisture and meteorological observations to validate soil moisture simulations with biosphere and bucket models

NASA Technical Reports Server (NTRS)

Robock, Alan; Vinnikov, Konstantin YA.; Schlosser, C. Adam; Speranskaya, Nina A.; Xue, Yongkang

1995-01-01

Soil moisture observations in sites with natural vegetation were made for several decades in the former Soviet Union at hundreds of stations. In this paper, the authors use data from six of these stations from different climatic regimes, along with ancillary meteorological and actinometric data, to demonstrate a method to validate soil moisture simulations with biosphere and bucket models. Some early and current general circulation models (GCMs) use bucket models for soil hydrology calculations. More recently, the Simple Biosphere Model (SiB) was developed to incorporate the effects of vegetation on fluxes of moisture, momentum, and energy at the earth's surface into soil hydrology models. Until now, the bucket and SiB have been verified by comparison with actual soil moisture data only on a limited basis. In this study, a Simplified SiB (SSiB) soil hydrology model and a 15-cm bucket model are forced by observed meteorological and actinometric data every 3 h for 6-yr simulations at the six stations. The model calculations of soil moisture are compared to observations of soil moisture, literally 'ground truth,' snow cover, surface albedo, and net radiation, and with each other. For three of the stations, the SSiB and 15-cm bucket models produce good simulations of seasonal cycles and interannual variations of soil moisture. For the other three stations, there are large errors in the simulations by both models. Inconsistencies in specification of field capacity may be partly responsible. There is no evidence that the SSiB simulations are superior in simulating soil moisture variations. In fact, the models are quite similar since SSiB implicitly has a bucket embedded in it. One of the main differences between the models is in the treatment of runoff due to melting snow in the spring -- SSiB incorrectly puts all the snowmelt into runoff. While producing similar soil moisture simulations, the models produce very different surface latent and sensible heat fluxes, which would have large effects on GCM simulations.

Assessment of the mechanical properties of the muscle-tendon unit by supersonic shear wave imaging elastography: a review

PubMed Central

2018-01-01

This review aimed to describe the state of the art in muscle-tendon unit (MTU) assessment by supersonic shear wave imaging (SSI) elastography in states of muscle contraction and stretching, during aging, and in response to injury and therapeutic interventions. A consensus exists that MTU elasticity increases during passive stretching or contraction, and decreases after static stretching, electrostimulation, massage, and dry needling. There is currently no agreement regarding changes in the MTU due to aging and injury. Currently, the application of SSI for the purpose of diagnosis, rehabilitation, and physical training remains limited by a number of issues, including the lack of normative value ranges, the lack of consensus regarding the appropriate terminology, and an inadequate understanding of the main technical limitations of this novel technology. PMID:28607322

The diagnostic performance of shear-wave elastography for liver fibrosis in children and adolescents: A systematic review and diagnostic meta-analysis.

PubMed

Kim, Jeong Rye; Suh, Chong Hyun; Yoon, Hee Mang; Lee, Jin Seong; Cho, Young Ah; Jung, Ah Young

2018-03-01

To assess the diagnostic performance of shear-wave elastography for determining the severity of liver fibrosis in children and adolescents. An electronic literature search of PubMed and EMBASE was conducted. Bivariate modelling and hierarchical summary receiver-operating-characteristic modelling were performed to evaluate the diagnostic performance of shear-wave elastography. Meta-regression and subgroup analyses according to the modality of shear-wave imaging and the degree of liver fibrosis were also performed. Twelve eligible studies with 550 patients were included. Shear-wave elastography showed a summary sensitivity of 81 % (95 % CI: 71-88) and a specificity of 91 % (95 % CI: 83-96) for the prediction of significant liver fibrosis. The number of measurements of shear-wave elastography performed was a significant factor influencing study heterogeneity. Subgroup analysis revealed shear-wave elastography to have an excellent diagnostic performance according to each degree of liver fibrosis. Supersonic shear imaging (SSI) had a higher sensitivity (p<.01) and specificity (p<.01) than acoustic radiation force impulse imaging (ARFI). Shear-wave elastography is an excellent modality for the evaluation of the severity of liver fibrosis in children and adolescents. Compared with ARFI, SSI showed better diagnostic performance for prediction of significant liver fibrosis. • Shear-wave elastography is beneficial for determining liver fibrosis severity in children. • Shear-wave elastography showed summary sensitivity of 81 %, specificity of 91 %. • SSI showed better diagnostic performance than ARFI for significant liver fibrosis.

Decadal climate simulations using the Climate Forecast System (CFS) coupled to the SSiB2 land surface model

NASA Astrophysics Data System (ADS)

De Sales, F.; Xue, Y.; Marx, L.; Ek, M. B.

2016-12-01

The Simplified Simple Biophysical version 2 (SSiB2) model was implemented in the NCEP Climate Forecast System (CFS) for two 30-yr simulations. One simulation was initialized from CFS reanalysis data (EXP1), and the other from a 10-yr spin-up run (EXP2), in which the ocean model was allowed to run freely while the atmosphere and land surface were maintained constant to adjust inconsistencies in the initial conditions. EXP2 also includes an update in the SSiB2's average soil water potential calculation. The material presented highlights the model's performance in predicting spatial and temporal variability of monthly precipitation and surface temperature and aims at determining the optimum configuration for longer simulations. In general, the model is able to reproduce the main features of large-scale precipitation, with spatial correlation (scorr) and RMSE of 0.8 and 1.4 mm day-1, respectively. A split ITCZ pattern is observed in the Pacific and Indian oceans, which results in dry biases along the equator and wet-bias bands to its north and south. Positive biases are also observed in the Atlantic ITCZ. The model generates consistent surface temperature climatology (scorr > 0.9, RMSE= 2.3°C). Warm biases are observed especially over southern Asia during summer. Both experiments produce similar precipitation climatology patterns with similar biases. EXP2, however, improves the temperature simulation by reducing the global bias by 48% and 26% during boreal winter and summer, respectively; and improves the temperature decadal variability for many areas. Moreover, EXP2 generates a better continental surface air warming trend. In the attempt to improve the precipitation decadal variability in the simulations, remotely-sensed LAI and vegetation cover fraction have been implemented in the CFS/SSiB2 to substitute the look-up table originally used in EXP1 and 2. The satellite vegetation data has been processed into global monthly maps which are continuous updated throughout the simulation. Results from this experiment will also be presented.

Risk Assessment of Abdominal Wall Thickness Measured on Pre-Operative Computerized Tomography for Incisional Surgical Site Infection after Abdominal Surgery.

PubMed

Tongyoo, Assanee; Chatthamrak, Putipan; Sriussadaporn, Ekkapak; Limpavitayaporn, Palin; Mingmalairak, Chatchai

2015-07-01

The surgical site infection (SSI) is a common complication of abdominal operation. It relates to increased hospital stay, increased healthcare cost, and decreased patient's quality of life. Obesity, usually defined by BMI, is known as one of the risks of SSI. However, the thickness of subcutaneous layers of abdominal wall might be an important local factor affecting the rate of SSI after the abdominal operations. The objective of this study is to assess the importance of the abdominal wall thickness on incisional SSI rate. The subjects of the present study were patients who had undergone major abdominal operations at Thammasat University Hospital between June 2013 and May 2014, and had been investigated with CT scans before their operations. The demographic data and clinical information of these patients were recorded. The thickness ofsubcutaneous fatty tissue from skin down to the most superficial layer of abdominal wall muscle at the surgical site was measured on CT images. The wound infectious complication was reviewed and categorized as superficial and deep incisional SSIfollowing the definition from Centersfor Disease Control and Prevention (CDC) guidelines. The significance ofeach potentialfactors on SSI rates was determined separately with student t-test for quantitative data and χ2-test for categorical data. Then all factors, which had p < 0.10, were included into the multivariate logistic regression analysis and were analyzed with significance at p < 0.05. One hundred and thirty-nine patients were included in this study. They all underwent major abdominal surgery and had had pre-operative CTscans. Post-operative SSI was 25.2% (35/139), superficial and deep types in 27 and 8 patients, respectively. The comparison of abdominal wall thickness between patients with and without infection was significantly different (20.0 ± 8.4 mm and 16.0 ± 7.2 mm, respectively). When the thickness at 20 mm was used as the cut-off value, 43 of 139 patients had abdominal wall thickness ≥ 20 mm. The incidence of SSI of the thickness ±20 mm group was 37.2% (16/43) and of the less thickness group was 19.8% (19/96), with p < 0.05. The univariate analysis revealed that abdominal wall thickness ≥ 20 mm, body weight ≥ 60 kg, and wound classification were the important factors related to SSI after the abdominal operation. However, only abdominal wall thickness and wound classification were still significant by multivariate analysis. The findings of this study confirmed the significance of the subcutaneous thickness of abdominal wall at the surgical site on the incidence of incisional SSI. The thickness ≥ 20 mm had an effect on increasing post operative SSI rate especially in contaminated operations. These findings could be helpful in making healthcare providers fully aware and thus exercise special attention in wound care or even develop new modalities to prevent SSI in patients with the aforementioned risks.

Spectrally Adaptable Compressive Sensing Imaging System

DTIC Science & Technology

2014-05-01

signal recovering [?, ?]. The time-varying coded apertures can be implemented using micro-piezo motors [?] or through the use of Digital Micromirror ...feasibility of this testbed by developing a Digital- Micromirror -Device-based Snapshot Spectral Imaging (DMD-SSI) system, which implements CS measurement...Y. Wu, I. O. Mirza, G. R. Arce, and D. W. Prather, ”Development of a digital- micromirror - device- based multishot snapshot spectral imaging

Europa Global Views in Natural and Enhanced Colors

NASA Technical Reports Server (NTRS)

1998-01-01

This color composite view combines violet, green, and infrared images of Jupiter's intriguing moon, Europa, for a view of the moon in natural color (left) and in enhanced color designed to bring out subtle color differences in the surface (right). The bright white and bluish part of Europa's surface is composed mostly of water ice, with very few non-ice materials. In contrast, the brownish mottled regions on the right side of the image may be covered by hydrated salts and an unknown red component. The yellowish mottled terrain on the left side of the image is caused by some other unknown component. Long, dark lines are fractures in the crust, some of which are more than 3,000 kilometers (1,850 miles) long.

North is to the top of the picture and the sun fully illuminates the surface. Europa is about 3,160 kilometers (1,950 miles) in diameter, or about the size of Earth's moon. The finest details that can be discerned are 25 kilometers across. The images in this global view were taken in June 1997 at a range of 1.25 million kilometers by the Solid State Imaging (SSI) system on NASA's Galileo spacecraft, during its ninth orbit of Jupiter.

The Jet Propulsion Laboratory, Pasadena, CA manages the Galileo mission for NASA's Office of Space Science, Washington, DC. JPL is an operating division of California Institute of Technology (Caltech).

This image and other images and data received from Galileo are posted on the World Wide Web, on the Galileo mission home page at URL http://galileo.jpl.nasa.gov. Background information and educational context for the images can be found at URL http://www.jpl.nasa.gov/galileo/sepo

Subaperture metrology technologies extend capabilities in optics manufacturing

NASA Astrophysics Data System (ADS)

Tricard, Marc; Forbes, Greg; Murphy, Paul

2005-10-01

Subaperture polishing technologies have radically changed the landscape of precision optics manufacturing and enabled the production of higher precision optics with increasingly difficult figure requirements. However, metrology is a critical piece of the optics fabrication process, and the dependence on interferometry is especially acute for computer-controlled, deterministic finishing. Without accurate full-aperture metrology, figure correction using subaperture polishing technologies would not be possible. QED Technologies has developed the Subaperture Stitching Interferometer (SSI) that extends the effective aperture and dynamic range of a phase measuring interferometer. The SSI's novel developments in software and hardware improve the capacity and accuracy of traditional interferometers, overcoming many of the limitations previously faced. The SSI performs high-accuracy automated measurements of spheres, flats, and mild aspheres up to 200 mm in diameter by stitching subaperture data. The system combines a six-axis precision workstation, a commercial Fizeau interferometer of 4" or 6" aperture, and dedicated software. QED's software automates the measurement design, data acquisition, and mathematical reconstruction of the full-aperture phase map. The stitching algorithm incorporates a general framework for compensating several types of errors introduced by the interferometer and stage mechanics. These include positioning errors, viewing system distortion, the system reference wave error, etc. The SSI has been proven to deliver the accurate and flexible metrology that is vital to precision optics fabrication. This paper will briefly review the capabilities of the SSI as a production-ready, metrology system that enables costeffective manufacturing of precision optical surfaces.

Study of persistent fog in Bulgaria with Sofia Stability Index, GNSS tropospheric products and WRF simulations

NASA Astrophysics Data System (ADS)

Stoycheva, Anastasiya; Manafov, Ilian; Vassileva, Keranka; Guerova, Guergana

2017-08-01

The topography of the high valley, in which the Bulgarian capital Sofia is located, predispose the seasonal character of fog formation in anticyclonic conditions. The fog in Sofia is mainly in the cold season, with the highest frequency of registrations in December and January. During the anticyclonic conditions the clear sky and calm or nearly calm conditions favour the formation of inversions and hence the fog formation. The maximum of fog registrations is at 6 UTC and minimum at 15 UTC but during prolonged fog a low visibility is registered also between 12 and 15 UTC. A prolonged fog is registered in Sofia between 3 and 10 January 2014 and is studied by using surface synoptic observations and vertically Integrated Water Vapour (IWV) derived from Global Navigation Satellite Systems (GNSS). The fog is separated in two parts: 1) part I - radiation fog (3-5 January) and 2) part II - advection fog (7-10 January). The Sofia Stability Index (SSI) is computed using surface temperature observation at 600 and 2300 m asl. The SSI is found to give additional information about the development and the dissipation of inversion layer especially for the part II fog. IWV is derived from two GNSS stations at 600 and 1120 m asl. and clearly detects the change in the air mass between the part I and II (5-6 January) fog. Furthermore, dependence between diurnal IWV cycle and fog formation/dissipation is found with IWV variation being lowest during the days with fog. A comparison of SSI and index computed using the WRF Numerical Weather Prediction model temperatures (SSI-W) shows good correlation but an negative off-set. Assimilation of surface and upper-air observations in the WRF model resulted in partial improvement of the index (10%), which is a result of moderate improvement of the vertical temperature profile.

Snow Physics and Meltwater Hydrology of the SSiB Model Employed for Climate Simulation Studies with GEOS 2 GCM

NASA Technical Reports Server (NTRS)

Mocko, David M.; Sud, Y. C.; Einaudi, Franco (Technical Monitor)

2000-01-01

Present-day climate models produce large climate drifts that interfere with the climate signals simulated in modelling studies. The simplifying assumptions of the physical parameterization of snow and ice processes lead to large biases in the annual cycles of surface temperature, evapotranspiration, and the water budget, which in turn causes erroneous land-atmosphere interactions. Since land processes are vital for climate prediction, and snow and snowmelt processes have been shown to affect Indian monsoons and North American rainfall and hydrology, special attention is now being given to cold land processes and their influence on the simulated annual cycle in GCMs. The snow model of the SSiB land-surface model being used at Goddard has evolved from a unified single snow-soil layer interacting with a deep soil layer through a force-restore procedure to a two-layer snow model atop a ground layer separated by a snow-ground interface. When the snow cover is deep, force-restore occurs within the snow layers. However, several other simplifying assumptions such as homogeneous snow cover, an empirical depth related surface albedo, snowmelt and melt-freeze in the diurnal cycles, and neglect of latent heat of soil freezing and thawing still remain as nagging problems. Several important influences of these assumptions will be discussed with the goal of improving them to better simulate the snowmelt and meltwater hydrology. Nevertheless, the current snow model (Mocko and Sud, 2000, submitted) better simulates cold land processes as compared to the original SSiB. This was confirmed against observations of soil moisture, runoff, and snow cover in global GSWP (Sud and Mocko, 1999) and point-scale Valdai simulations over seasonal snow regions. New results from the current snow model SSiB from the 10-year PILPS 2e intercomparison in northern Scandinavia will be presented.

NIMS: hotspots on Io during G2 (continued)

NASA Technical Reports Server (NTRS)

1997-01-01

This is another Near Infrared Mapping Spectrometer (NIMS) image of Io, taken during the G2 encounter in September 1996. This is a dayside image of Io (on the right) against the clouds of Jupiter (the blue background). On the left is a Voyager mosaic of Io with the same viewing geometry for comparison purposes. This NIMS data set has been processed to highlight the positions of hot spots on the surface of Io. At least 11 can be seen. Two of the hotspots are newly discovered by the NIMS instrument. Others correspond to sites of plume eruptions and volcanic calderas and volcanic flows. This image can be compared with the SSI image P-47971 released on October 23, 1996, which was taken almost exactly the same position.

The Jet Propulsion Laboratory, Pasadena, CA manages the mission for NASA's Office of Space Science, Washington, DC.

The Jet Propulsion Laboratory, Pasadena, CA manages the mission for NASA's Office of Space Science, Washington, DC.

This image and other images and data received from Galileo are posted on the World Wide Web, on the Galileo mission home page at URL http://galileo.jpl.nasa.gov.

Volcanic activity at Tvashtar Catena, Io

USGS Publications Warehouse

Milazzo, M.P.; Keszthelyi, L.P.; Radebaugh, J.; Davies, A.G.; Turtle, E.P.; Geissler, P.; Klaasen, K.P.; Rathbun, J.A.; McEwen, A.S.

2005-01-01

Galileo's Solid State Imager (SSI) observed Tvashtar Catena four times between November 1999 and October 2001, providing a unique look at a distinctive high latitude volcanic complex on Io. The first observation (orbit I25, November 1999) resolved, for the first time, an active extraterrestrial fissure eruption; the brightness temperature was at least 1300 K. The second observation (orbit I27, February 2000) showed a large (??? 500 km 2) region with many, small, hot, regions of active lava. The third observation was taken in conjunction with Cassini imaging in December 2000 and showed a Pele-like, annular plume deposit. The Cassini images revealed an ???400 km high Pele-type plume above Tvashtar Catena. The final Galileo SSI observation of Tvashtar (orbit I32, October 2001), revealed that obvious (to SSI) activity had ceased, although data from Galileo's Near Infrared Mapping Spectrometer (NIMS) indicated that there was still significant thermal emission from the Tvashtar region. In this paper, we primarily analyze the style of eruption during orbit I27 (February 2000). Comparison with a lava flow cooling model indicates that the behavior of the Tvashtar eruption during I27 does not match that of simple advancing lava flows. Instead, it may be an active lava lake or a complex set of lava flows with episodic, overlapping eruptions. The highest reliable color temperature is ???1300 K. Although higher temperatures cannot be ruled out, they do not need to be invoked to fit the observed data. The total power output from the active lavas in February 2000 was at least 1011 W. ?? 2005 Elsevier Inc. All rights reserved.

Europa 'Ice Rafts' in local and color context

NASA Technical Reports Server (NTRS)

1998-01-01

This image of Jupiter's icy satellite Europa shows surface features such as domes and ridges, as well as a region of disrupted terrain including crustal plates which are thought to have broken apart and 'rafted' into new positions. The image covers an area of Europa's surface about 250 by 200 kilometer (km) and is centered at 10 degrees latitude, 271 degrees longitude. The color information allows the surface to be divided into three distinct spectral units. The bright white areas are ejecta rays from the relatively young crater Pwyll, which is located about 1000 km to the south (bottom) of this image. These patchy deposits appear to be superposed on other areas of the surface, and thus are thought to be the youngest features present. Also visible are reddish areas which correspond to locations where non-ice components are present. This coloring can be seen along the ridges, in the region of disrupted terrain in the center of the image, and near the dome-like features where the surface may have been thermally altered. Thus, areas associated with internal geologic activity appear reddish. The third distinct color unit is bright blue, and corresponds to the relatively old icy plains.

This product combines data taken by the Solid State Imaging (SSI) system on NASA's Galileo spacecraft during three separate flybys of Europa. Low resolution color data (violet, green, and 1 micron) acquired in September 1996 were combined with medium resolution images from December 1996, to produce synthetic color images. These were then combined with a high resolution mosaic of images acquired in February 1997.

The Jet Propulsion Laboratory, Pasadena, CA manages the Galileo mission for NASA's Office of Space Science, Washington, DC. JPL is an operating division of California Institute of Technology (Caltech).

This image and other images and data received from Galileo are posted on the World Wide Web, on the Galileo mission home page at URL http://galileo.jpl.nasa.gov. Background information and educational context for the images can be found at URL http://www.jpl.nasa.gov/galileo/sepo

Surgical Site Infections Following Pediatric Ambulatory Surgery: An Epidemiologic Analysis.

PubMed

Rinke, Michael L; Jan, Dominique; Nassim, Janelle; Choi, Jaeun; Choi, Steven J

2016-08-01

OBJECTIVE To identify surgical site infection (SSI) rates following pediatric ambulatory surgery, SSI outcomes and risk factors, and sensitivity and specificity of SSI administrative billing codes. DESIGN Retrospective chart review of pediatric ambulatory surgeries with International Classification of Disease, Ninth Revision (ICD-9) codes for SSI, and a systematic random sampling of 5% of surgeries without SSI ICD-9 codes, all adjudicated for SSI on the basis of an ambulatory-adapted National Healthcare Safety Network definition. SETTING Urban pediatric tertiary care center April 1, 2009-March 31, 2014. METHODS SSI rates and sensitivity and specificity of ICD-9 codes were estimated using sampling design, and risk factors were analyzed in case-rest of cohort, and case-control, designs. RESULTS In 15,448 pediatric ambulatory surgeries, 34 patients had ICD-9 codes for SSI and 25 met the adapted National Healthcare Safety Network criteria. One additional SSI was identified with systematic random sampling. The SSI rate following pediatric ambulatory surgery was 2.9 per 1,000 surgeries (95% CI, 1.2-6.9). Otolaryngology surgeries demonstrated significantly lower SSI rates compared with endocrine (P=.001), integumentary (P=.001), male genital (P<.0001), and respiratory (P=.01) surgeries. Almost half of patients with an SSI were admitted, 88% received antibiotics, and 15% returned to the operating room. No risk factors were associated with SSI. The sensitivity of ICD-9 codes for SSI following ambulatory surgery was 55.31% (95% CI, 12.69%-91.33%) and specificity was 99.94% (99.89%-99.97%). CONCLUSIONS SSI following pediatric ambulatory surgery occurs at an appreciable rate and conveys morbidity on children. Infect Control Hosp Epidemiol 2016;37:931-938.

Impact of a surgical site infection reduction strategy after colorectal resection.

PubMed

Connolly, T M; Foppa, C; Kazi, E; Denoya, P I; Bergamaschi, R

2016-09-01

This study was performed to determine the impact of a surgical site infection (SSI) reduction strategy on SSI rates following colorectal resection. American College of Surgeons National Surgical Quality Improvement Program (NSQIP) data from 2006-14 were utilized and supplemented by institutional review board-approved chart review. The primary end-point was superficial and deep incisional SSI. The inclusion criterion was colorectal resection. The SSI reduction strategy consisted of preoperative (blood glucose, bowel preparation, shower, hair removal), intra-operative (prophylactic antibiotics, antimicrobial incisional drape, wound protector, wound closure technique) and postoperative (wound dressing technique) components. The SSI reduction strategy was prospectively implemented and compared with historical controls (pre-SSI strategy arm). Statistical analysis included Pearson's chi-square test, and Student's t-test performed with spss software. Of 1018 patients, 379 were in the pre-SSI strategy arm, 311 in the SSI strategy arm and 328 were included to test durability. The study arms were comparable for all measured parameters. Preoperative wound class, operation time, resection type and stoma creation did not differ significantly. The SSI strategy arm demonstrated a significant decrease in overall SSI rates (32.19% vs 18.97%) and superficial SSI rates (23.48% vs 8.04%). Deep SSI and organ space rates did not differ. A review of patients testing durability demonstrated continued improvement in overall SSI rates (8.23%). The implementation of an SSI reduction strategy resulted in a 41% decrease in SSI rates following colorectal resection over its initial 3 years, and its durability as demonstrated by continuing improvement was seen over an additional 2 years. Colorectal Disease © 2015 The Association of Coloproctology of Great Britain and Ireland.

GISS GCMAM Modeled Climate Responses to Total and Spectral Solar Forcing on Decadal and Centennial Time Scales

NASA Astrophysics Data System (ADS)

Wen, Guoyong; Cahalan, Robert; Rind, David; Jonas, Jeffrey; Pilewskie, Peter; Harder, Jerry

2014-05-01

We examine the influence of the SORCE (Solar Radiation and Climate Experiment) SIM (Spectral Irradiance Monitor) observed spectral solar irradiance (SSI) variations on Earth's climate. We apply two reconstructed spectral solar forcing scenarios, one SIM based, the other based on the SATIRE (Spectral And Total Irradiance REconstruction) model, as inputs to the GISS (Goddard Institute for Space Studies) GCMAM (Global Climate Middle Atmosphere Model) to examine the climate responses on decadal and centennial time scales. We show that the atmosphere has different temperature, ozone, and dynamic responses to the two solar spectral forcing scenarios, even when the variations in TSI (Total Solar Irradiance) are the same. We find that solar variations under either scenario contribute a small fraction of the observed temperature increase since the industrial revolution. The trend of global averaged surface air temperature response to the SIM-based solar forcing is 0.02 °C/century, about half of the temperature trend to the SATIRE-based SSI. However the temporal variation of the surface air temperature for the SIM-based solar forcing scenario is much larger compared to its SATIRE counterpart. Further research is required to examine TSI and SSI variations in the ascending phase of solar cycle 24, to assess their implications for the solar influence on climate.

GISS GCMAM Modeled Climate Responses to Total and Spectral Solar Forcing on Decadal and Centennial Time Scales

NASA Astrophysics Data System (ADS)

Wen, G.; Cahalan, R. F.; Rind, D. H.; Jonas, J.; Pilewskie, P.; Harder, J. W.; Krivova, N.

2014-12-01

We examine the influence of the SORCE (Solar Radiation and Climate Experiment) SIM (Spectral Irradiance Monitor) observed spectral solar irradiance (SSI) variations on Earth's climate. We apply two reconstructed spectral solar forcing scenarios, one SIM based, the other based on the SATIRE (Spectral And Total Irradiance REconstruction) model, as inputs to the GISS (Goddard Institute for Space Studies) GCMAM (Global Climate Middle Atmosphere Model) to examine the climate responses on decadal and centennial time scales. We show that the atmosphere has different temperature, ozone, and dynamic responses to the two solar spectral forcing scenarios, even when the variations in TSI (Total Solar Irradiance) are the same. We find that solar variations under either scenario contribute a small fraction of the observed temperature increase since the industrial revolution. The trend of global averaged surface air temperature response to the SIM-based solar forcing is 0.02 °C/century, about half of the temperature trend to the SATIRE-based SSI. However the temporal variation of the surface air temperature for the SIM-based solar forcing scenario is much larger compared to its SATIRE counterpart. Further research is required to examine TSI and SSI variations in the ascending phase of solar cycle 24, to assess their implications for the solar influence on climate.

Complete Soil-Structure Interaction (SSI) Analyses of I-walls Embedded in Level Ground During Flood Loading

DTIC Science & Technology

2012-09-01

at the ground surface el 0 ft versus water elevation...sheet pile at the ground surface . ................ 62  Figure 3.24. Total displacements for a water elevation of 16.5 ft and a gap tip elevation of -11...103  Figure 4.19. Relative horizontal displacements of the sheet pile at the ground surface

Fractography used with lifetime prediction tests on commercial grades of alumina and silicon carbide

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kuebler, J.; Woodtli, J.; Berroth, K.

1996-12-31

Fractographic investigations were conducted on alumina and {alpha}-SSiC bend bars from a round robin test comparing a static and a dynamic lifetime test method. The investigations revealed that not all fracture origins found on {alpha}-SSiC specimens had contact with the ambient medium and therefore the dynamic lifetime tests did not measure the materials` behaviour under stress in water. In addition to the conventional SEM fractography an alternate technique, using an auto focus scanning laser profilometer was applied for characterizing the fractures. This tool is very promising for fractography because of the ability to handle topographic data by imaging procedures andmore » fractal analysis.« less

Culturally Equipped for Socio-Scientific Issues? A comparative study on how teachers and students in mono- and multiethnic schools handle work with complex issues

NASA Astrophysics Data System (ADS)

Ideland, Malin; Malmberg, Claes; Winberg, Mikael

2011-09-01

Socio-scientific issues (SSI) are not only said to increase students' interest in science, but they also strengthen the generic skills of teamwork, problem-solving, and media literacy. At the same time, these skills are prerequisites for successful work with SSI. The aim of the study is to analyze what happens when SSI are implemented in science classrooms with various degrees of ethnic diversity and socio-cultural status. We are also interested in knowing how teachers structure the SSI work from discourses on what suits different students. Quantitative and qualitative methods are combined, for example, questionnaires and ethnographic fieldwork, presented through partial least squares analysis and thick descriptions. We can notice discursive differences between 'Us' and 'The Other' and between mono- and multiethnic schools. In an earlier research, images of differences between the different student groups emerged, and we can find these in the results from the questionnaires. In an observation study, another pattern appeared that indicated similarities rather than differences between mono- and multiethnic classrooms. The students are first of all inside the discourse of 'the successful student.' Noteworthy is that the teachers' roles correspond better with the discourse than with how students actually act. The study also shows that SSI articulate a collision between different discourses on education: a discourse on differences between students in multi- and monoethnic classrooms; a discourse on how to become a successful student; and a discourse on the school's mission to educate participating citizens. It is suggested that schools should relate to, expose, and articulate discursive clashes that emerge when introducing new work forms.

Calibration of the ``Simplified Simple Biosphere Model—SSiB'' for the Brazilian Northeast Caatinga

NASA Astrophysics Data System (ADS)

do Amaral Cunha, Ana Paula Martins; dos Santos Alvalá, Regina Célia; Correia, Francis Wagner Silva; Kubota, Paulo Yoshio

2009-03-01

The Brazilian Northeast region is covered largely by vegetation adapted to the arid conditions and with varied physiognomy, called caatinga. It occupies an extension of about 800.000 km2 that corresponds to 70% of the region. In recent decades, considerable progress in understanding the micrometeorological processes has been reached, with results that were incorporated into soil-vegetation-atmosphere transfer schemes (SVATS) to study the momentum, energy, water vapor, carbon cycle and vegetation dynamics changes of different ecosystems. Notwithstanding, the knowledge of the parameters and physical or physiological characteristics of the vegetation and soil of the caatinga region is very scarce. So, the objective of this work was performing a calibration of the parameters of the SSiB model for the Brazilian Northeast Caatinga. Micrometeorological and hydrological data collected from July 2004 to June 2005, obtained in the Agricultural Research Center of the Semi-Arid Tropic (CPATSA), were used. Preceding the calibration process, a sensibility study of the SSiB model was performed in order to find the parameters that are sensible to the exchange processes between the surface and atmosphere. The results showed that the B parameter, soil moisture potential at saturation (ψs), hydraulic conductivity of saturated soil (ks) and the volumetric moisture at saturation (θs) present high variations on turbulent fluxes. With the initial parameters, the SSiB model showed best results for net radiation, and the latent heat (sensible heat) flux was over-estimated (under-estimated) for all simulation periods. Considering the calibrated parameters, better values of latent flux and sensible flux were obtained. The calibrated parameters were also used for a validation of the surface fluxes considering data from July 2005 to September 2005. The results showed that the model generated better estimations of latent heat and sensible heat fluxes, with low root mean square error. With better estimations of the turbulent fluxes, it was possible to obtain a more representative energy partitioning for the caatinga. Therefore, it is expected that from this calibrated SSiB model, coupled to the meteorological models, it will be possible to obtain more realistic climate and weather forecasts for the Brazilian Northeast region.

Sternal wound infection after cardiac surgery: incidence and risk factors according to clinical presentation.

PubMed

Lemaignen, A; Birgand, G; Ghodhbane, W; Alkhoder, S; Lolom, I; Belorgey, S; Lescure, F-X; Armand-Lefevre, L; Raffoul, R; Dilly, M-P; Nataf, P; Lucet, J C

2015-07-01

The incidence of surgical site infection (SSI) after cardiac surgery depends on the definition used. A distinction is generally made between mediastinitis, as defined by the US Centers for Disease Control and Prevention (CDC), and superficial SSI. Our objective was to decipher these entities in terms of presentation and risk factors. We performed a 7-year single centre analysis of prospective surveillance of patients with cardiac surgery via median sternotomy. SSI was defined as the need for reoperation due to infection. Among 7170 patients, 292 (4.1%) developed SSI, including 145 CDC-defined mediastinitis (CDC-positive SSI, 2.0%) and 147 superficial SSI without associated bloodstream infection (CDC-negative SSI, 2.1%). Median time to reoperation for CDC-negative SSI was 18 days (interquartile range, 14-26) and 16 (interquartile range, 11-24) for CDC-positive SSI (p 0.02). Microorganisms associated with CDC-negative SSI were mainly skin commensals (62/147, 41%) or originated in the digestive tract (62/147, 42%); only six were due to Staphylococcus aureus (4%), while CDC-positive SSI were mostly due to S. aureus (52/145, 36%) and germs from the digestive tract (52/145, 36%). Risk factors for SSI were older age, obesity, chronic obstructive bronchopneumonia, diabetes mellitus, critical preoperative state, postoperative vasopressive support, transfusion or prolonged ventilation and coronary artery bypass grafting, especially if using both internal thoracic arteries in female patients. The number of internal thoracic arteries used and factors affecting wound healing were primarily associated with CDC-negative SSI, whereas comorbidities and perioperative complications were mainly associated with CDC-positive SSI. These 2 entities differed in time to revision surgery, bacteriology and risk factors, suggesting a differing pathophysiology. Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

Five-year decreased incidence of surgical site infections following gastrectomy and prosthetic joint replacement surgery through active surveillance by the Korean Nosocomial Infection Surveillance System.

PubMed

Choi, H J; Adiyani, L; Sung, J; Choi, J Y; Kim, H B; Kim, Y K; Kwak, Y G; Yoo, H; Lee, Sang-Oh; Han, S H; Kim, S R; Kim, T H; Lee, H M; Chun, H K; Kim, J-S; Yoo, J D; Koo, H-S; Cho, E H; Lee, K W

2016-08-01

Surveillance of healthcare-associated infection has been associated with a reduction in surgical site infection (SSI). To evaluate the Korean Nosocomial Infection Surveillance System (KONIS) in order to assess its effects on SSI since it was introduced. SSI data after gastrectomy, total hip arthroplasty (THA), and total knee arthroplasty (TKA) between 2008 and 2012 were analysed. The pooled incidence of SSI was calculated for each year; the same analyses were also conducted from hospitals that had participated in KONIS for at least three consecutive years. Standardized SSI rates for each year were calculated by adjusting for SSI risk factors. SSI trends were analysed using the Cochran-Armitage test. The SSI rate following gastrectomy was 3.12% (522/16,918). There was a significant trend of decreased crude SSI rates over five years. This trend was also evident in analysis of hospitals that had participated for more than three years. The SSI rate for THA was 2.05% (157/7656), which decreased significantly from 2008 to 2012. The risk factors for SSI after THA included the National Nosocomial Infections Surveillance risk index, trauma, reoperation, and age (60-69 years). The SSI rate for TKA was 1.90% (152/7648), which also decreased significantly during a period of five years. However, the risk-adjusted analysis of SSI did not show a significant decrease for all surgical procedures. The SSI incidence of gastrectomy and prosthetic joint replacement declined over five years as a result of active surveillance by KONIS. Copyright © 2016 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

Degradation and Deformation of Scarps and Slopes on Io: New Results

NASA Technical Reports Server (NTRS)

Moore, J. M.; Sullivan, R. J.; Pappalardo, R. T.; Turtle, E. P.

2000-01-01

Initial analysis of degradational processes on scarps and slopes on Io using just-acquired images by the Galileo SSI team. Among other results, is evidence for sublimation, sapping, and perhaps "glacial" flow of interstitial volatiles in relief-forming materials.

The DMSP Space Weather Sensors Data Archive Listing (1982-2013) and File Formats Descriptions

DTIC Science & Technology

2014-08-01

environment sensors including the auroral particle spectrometer (SSJ), the fluxgate magnetometer (SSM), the topside thermal plasma monitor (SSIES... Fluxgate Magnetometer (SSM) for the Defense Meteorological Satellite Program (DMSP) Block 5D-2, Flight 7, Instrument Papers, AFGL-TR-84-0225; ADA155229...Flux) SSM The fluxgate magnetometer . (Special Sensor, Magnetometer ) SSULI The ultraviolet limb imager SSUSI The ultraviolet spectrographic imager

Lunar Resources Using Moderate Spectral Resolution Visible and Near-infrared Spectroscopy: Al/si and Soil Maturity

NASA Technical Reports Server (NTRS)

Fischer, Erich M.; Pieters, Carle M.; Head, James W.

1992-01-01

Modern visible and near-infrared detectors are critically important for the accurate identification and relative abundance measurement of lunar minerals; however, even a very small number of well-placed visible and near-infrared bandpass channels provide a significant amount of general information about crucial lunar resources. The Galileo Solid State Imaging system (SSI) multispectral data are an important example of this. Al/Si and soil maturity will be discussed as examples of significant general lunar resource information that can be gleaned from moderate spectral resolution visible and near-infrared data with relative ease. Because quantitative-albedo data are necessary for these kinds of analyses, data such as those obtained by Galileo SSI are critical. SSI obtained synoptic digital multispectral image data for both the nearside and farside of the Moon during the first Galileo Earth-Moon encounter in December 1990. The data consist of images through seven filters with bandpasses ranging from 0.40 microns in the ultraviolet to 0.99 microns in the near-infrared. Although these data are of moderate spectral resolution, they still provide information for the following lunar resources: (1) titanium content of mature mare soils based upon the 0.40/0.56-micron (UV/VIS) ratio; (2) mafic mineral abundance based upon the 0.76/0.99-micron ratio; and (3) the maturity or exposure age of the soils based upon the 0.56-0.76-micron continuum and the 0.76/0.99-micron ratio. Within constraints, these moderate spectral resolution visible and near-infrared reflectance data can also provide elemental information such as Al/Si for mature highland soils.

Agreement among health care professionals in diagnosing case Vignette-based surgical site infections.

PubMed

Lepelletier, Didier; Ravaud, Philippe; Baron, Gabriel; Lucet, Jean-Christophe

2012-01-01

To assess agreement in diagnosing surgical site infection (SSI) among healthcare professionals involved in SSI surveillance. Case-vignette study done in 2009 in 140 healthcare professionals from seven specialties (20 in each specialty, Anesthesiologists, Surgeons, Public health specialists, Infection control physicians, Infection control nurses, Infectious diseases specialists, Microbiologists) in 29 University and 36 non-University hospitals in France. We developed 40 case-vignettes based on cardiac and gastrointestinal surgery patients with suspected SSI. Each participant scored six randomly assigned case-vignettes before and after reading the SSI definition on an online secure relational database. The intraclass correlation coefficient (ICC) was used to assess agreement regarding SSI diagnosis on a seven-point Likert scale and the kappa coefficient to assess agreement for superficial or deep SSI on a three-point scale. Based on a consensus, SSI was present in 21 of 40 vignettes (52.5%). Intraspecialty agreement for SSI diagnosis ranged across specialties from 0.15 (95% confidence interval, 0.00-0.59) (anesthesiologists and infection control nurses) to 0.73 (0.32-0.90) (infectious diseases specialists). Reading the SSI definition improved agreement in the specialties with poor initial agreement. Intraspecialty agreement for superficial or deep SSI ranged from 0.10 (-0.19-0.38) to 0.54 (0.25-0.83) (surgeons) and increased after reading the SSI definition only among the infection control nurses from 0.10 (-0.19-0.38) to 0.41 (-0.09-0.72). Interspecialty agreement for SSI diagnosis was 0.36 (0.22-0.54) and increased to 0.47 (0.31-0.64) after reading the SSI definition. Among healthcare professionals evaluating case-vignettes for possible surgical site infection, there was large disagreement in diagnosis that varied both between and within specialties.

A Persian-version of the stuttering severity instrument-version four (SSI-4): How the new additions to SSI-4 complement its stuttering severity score?

PubMed

Tahmasebi, Neda; Shafie, Bijan; Karimi, Hamid; Mazaheri, Masood

The fourth version of the Stuttering Severity Instrument (SSI-4) has been available since 2009. It has some modifications and new features which make it more appropriate at least for clinical practice, although further documentation is needed. The objective of the current research was to translate SSI-4 into Persian language and to discuss its relative and absolute reliability as well as its criterion validity for Persian adults who stutter (PWS). We also aimed to study how the new subjective self-reports of the SSI-4 complement the stuttering severity score obtained from the SSI-3 or the SSI-4. The cross-cultural guideline recommended by the International Quality of Life Assessment project was used to translate the SSI-4 into Persian language. Thirty five PWS from ages 17 to 42 were recruited and 10 speech and language pathologists assessed their stuttering severity using either the SSI-4 or stuttering severity ratings (SR) to test validity and reliability of the Persian translated version. A very high inter-judge relative reliability along with a poor absolute inter-judge reliability was found for the SSI-4 scores. The results were more promising for the intra-judge absolute reliability. Test-retest reliability of the complementary questions to the SSI-4 was also found acceptable. However, no strong relationship was found between the SSI-4 scores and its complementary questions. The Persian version of the SSI-4 can be used reliably by trained SLPs for research and clinical purposes, but not to document small changes in stuttering severity. We argue that the response of participants to the complementary self-report questions should also be considered in calculating their stuttering severity score. Copyright © 2018 Elsevier Inc. All rights reserved.

Agreement among healthcare professionals in ten European countries in diagnosing case-vignettes of surgical-site infections.

PubMed

Birgand, Gabriel; Lepelletier, Didier; Baron, Gabriel; Barrett, Steve; Breier, Ann-Christin; Buke, Cagri; Markovic-Denic, Ljiljana; Gastmeier, Petra; Kluytmans, Jan; Lyytikainen, Outi; Sheridan, Elizabeth; Szilagyi, Emese; Tacconelli, Evelina; Troillet, Nicolas; Ravaud, Philippe; Lucet, Jean-Christophe

2013-01-01

Although surgical-site infection (SSI) rates are advocated as a major evaluation criterion, the reproducibility of SSI diagnosis is unknown. We assessed agreement in diagnosing SSI among specialists involved in SSI surveillance in Europe. Twelve case-vignettes based on suspected SSI were submitted to 100 infection-control physicians (ICPs) and 86 surgeons in 10 European countries. Each participant scored eight randomly-assigned case-vignettes on a secure online relational database. The intra-class correlation coefficient (ICC) was used to assess agreement for SSI diagnosis on a 7-point Likert scale and the kappa coefficient to assess agreement for SSI depth on a three-point scale. Intra-specialty agreement for SSI diagnosis ranged across countries and specialties from 0.00 (95%CI, 0.00-0.35) to 0.65 (0.45-0.82). Inter-specialty agreement varied from 0.04 (0.00-0.62) in to 0.55 (0.37-0.74) in Germany. For all countries pooled, intra-specialty agreement was poor for surgeons (0.24, 0.14-0.42) and good for ICPs (0.41, 0.28-0.61). Reading SSI definitions improved agreement among ICPs (0.57) but not surgeons (0.09). Intra-specialty agreement for SSI depth ranged across countries and specialties from 0.05 (0.00-0.10) to 0.50 (0.45-0.55) and was not improved by reading SSI definition. Among ICPs and surgeons evaluating case-vignettes of suspected SSI, considerable disagreement occurred regarding the diagnosis, with variations across specialties and countries.

Agreement among Healthcare Professionals in Ten European Countries in Diagnosing Case-Vignettes of Surgical-Site Infections

PubMed Central

Birgand, Gabriel; Lepelletier, Didier; Baron, Gabriel; Barrett, Steve; Breier, Ann-Christin; Buke, Cagri; Markovic-Denic, Ljiljana; Gastmeier, Petra; Kluytmans, Jan; Lyytikainen, Outi; Sheridan, Elizabeth; Szilagyi, Emese; Tacconelli, Evelina; Troillet, Nicolas; Ravaud, Philippe; Lucet, Jean-Christophe

2013-01-01

Objective Although surgical-site infection (SSI) rates are advocated as a major evaluation criterion, the reproducibility of SSI diagnosis is unknown. We assessed agreement in diagnosing SSI among specialists involved in SSI surveillance in Europe. Methods Twelve case-vignettes based on suspected SSI were submitted to 100 infection-control physicians (ICPs) and 86 surgeons in 10 European countries. Each participant scored eight randomly-assigned case-vignettes on a secure online relational database. The intra-class correlation coefficient (ICC) was used to assess agreement for SSI diagnosis on a 7-point Likert scale and the kappa coefficient to assess agreement for SSI depth on a three-point scale. Results Intra-specialty agreement for SSI diagnosis ranged across countries and specialties from 0.00 (95%CI, 0.00–0.35) to 0.65 (0.45–0.82). Inter-specialty agreement varied from 0.04 (0.00–0.62) in to 0.55 (0.37–0.74) in Germany. For all countries pooled, intra-specialty agreement was poor for surgeons (0.24, 0.14–0.42) and good for ICPs (0.41, 0.28–0.61). Reading SSI definitions improved agreement among ICPs (0.57) but not surgeons (0.09). Intra-specialty agreement for SSI depth ranged across countries and specialties from 0.05 (0.00–0.10) to 0.50 (0.45–0.55) and was not improved by reading SSI definition. Conclusion Among ICPs and surgeons evaluating case-vignettes of suspected SSI, considerable disagreement occurred regarding the diagnosis, with variations across specialties and countries. PMID:23874690

Development of a surgical site infection (SSI) surveillance system, calculation of SSI rates and specification of important factors affecting SSI in a digestive organ surgical department.

PubMed

Kimura, Koji; Sawa, Akihiro; Akagi, Shinji; Kihira, Kenji

2007-06-01

We have developed an original system to conduct surgical site infection (SSI) surveillance. This system accumulates SSI surveillance information based on the National Nosocomial Infections Surveillance (NNIS) System and the Japanese Nosocomial Infections Surveillance (JNIS) System. The features of this system are as follows: easy input of data, high generality, data accuracy, SSI rate by operative procedure and risk index category (RIC) can be promptly calculated and compared with the current NNIS SSI rate, and the SSI rates and accumulated data can be exported electronically. Using this system, we monitored 798 patients in 24 operative procedure categories in the Digestive Organs Surgery Department of Mazda Hospital, Mazda Motor Corporation, from January 2004 through December 2005. The total number and rate of SSI were 47 and 5.89%, respectively. The SSI rates of 777 patients were calculated based on 15 operative procedure categories and Risk Index Categories (RIC). The highest SSI rate was observed in the rectum surgery of RIC 1 (30%), followed by the colon surgery of RIC3 (28.57%). About 30% of the isolated infecting bacteria were Enterococcus faecalis, Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Escherichia coli. Using quantification theory type 2, the American Society of Anesthesiology score (4.531), volume of hemorrhage under operation (3.075), wound classification (1.76), operation time (1.352), and history of diabetes (0.989) increased to higher ranks as factors for SSI. Therefore, we evaluated this system as a useful tool in safety control for operative procedures.

Controlled photomosaic map of Europa Je 15 M CMN

USGS Publications Warehouse

,

2002-01-01

This sheet is one in a series of maps of the Galilean satellites of Jupiter at a nominal scale of 1:15,000,000. This series is based on data from the Galileo Orbiter Solid-State Imaging (SSI) camera and the Voyager 1 and 2 spacecraft.

Surgical site infection after breast surgery: impact of 2010 CDC reporting guidelines.

PubMed

Degnim, Amy C; Throckmorton, Alyssa D; Boostrom, Sarah Y; Boughey, Judy C; Holifield, Andrea; Baddour, Larry M; Hoskin, Tanya L

2012-12-01

Reported surgical site infection (SSI) rates after breast operations ranges 0.8-26 % in the literature. The aims of the present study were to characterize SSI after breast/axillary operations and determine the impact on the SSI rate of the 2010 Centers for Disease Control and Prevention (CDC) reporting guidelines that now specifically exclude cellulitis. Retrospective chart review identified 368 patients with 449 operated sides between July 2004 and June 2006. SSI was defined by CDC criteria: purulent drainage (category 1), positive aseptically collected culture (category 2), signs of inflammation with opening of incision and absence of negative culture (category 3), and physician diagnosis of infection (category 4). The impact of excluding cellulitis was assessed. Prior CDC reporting guidelines revealed that among 368 patients, 32 (8.7 %) experienced SSI in 33 (7.3 %) of 449 operated sides. Of these, 11 (33 %) met CDC criteria 1-3, while 22 (67 %) met CDC criterion 4. Excluding cellulitis cases per 2010 CDC SSI reporting guidelines eliminates 21 of the 22 infections previously meeting CDC criterion 4. Under the new reporting guidelines, the SSI rate is 12 (2.7 %) of 449 operated sides. SSI rates varied by procedure, but these differences were not statistically significant. Cellulitis after breast and axillary surgery is much more common than other criteria for SSI, and SSI rates are reduced almost threefold if cellulitis cases are excluded. Recently revised CDC reporting guidelines may result in underestimates of the clinical burden of SSI after breast/axillary surgery.

Improving Public Reporting and Data Validation for Complex Surgical Site Infections After Coronary Artery Bypass Graft Surgery and Hip Arthroplasty

PubMed Central

Calderwood, Michael S.; Kleinman, Ken; Murphy, Michael V.; Platt, Richard; Huang, Susan S.

2014-01-01

Background  Deep and organ/space surgical site infections (D/OS SSI) cause significant morbidity, mortality, and costs. Rates are publicly reported and increasingly used as quality metrics affecting hospital payment. Lack of standardized surveillance methods threaten the accuracy of reported data and decrease confidence in comparisons based upon these data. Methods  We analyzed data from national validation studies that used Medicare claims to trigger chart review for SSI confirmation after coronary artery bypass graft surgery (CABG) and hip arthroplasty. We evaluated code performance (sensitivity and positive predictive value) to select diagnosis codes that best identified D/OS SSI. Codes were analyzed individually and in combination. Results  Analysis included 143 patients with D/OS SSI after CABG and 175 patients with D/OS SSI after hip arthroplasty. For CABG, 9 International Classification of Diseases, 9th Revision (ICD-9) diagnosis codes identified 92% of D/OS SSI, with 1 D/OS SSI identified for every 4 cases with a diagnosis code. For hip arthroplasty, 6 ICD-9 diagnosis codes identified 99% of D/OS SSI, with 1 D/OS SSI identified for every 2 cases with a diagnosis code. Conclusions  This standardized and efficient approach for identifying D/OS SSI can be used by hospitals to improve case detection and public reporting. This method can also be used to identify potential D/OS SSI cases for review during hospital audits for data validation. PMID:25734174

How do we understand the disagreement in the frequency of surgical site infection between the CDC and Clavien-Dindo classifications?

PubMed

Yamamoto, Takanobu; Takahashi, Satoshi; Ichihara, Koji; Hiyama, Yoshiki; Uehara, Teruhisa; Hashimoto, Jiro; Hirobe, Megumi; Masumori, Naoya

2015-02-01

To clarify the discrepancy in the incidence and severity of surgical site infections (SSI) for radical cystectomy between reports based on the CDC guideline and those using the Clavien-Dindo classification we evaluated 449 consecutive patients who underwent radical cystectomy for bladder cancer between 1990 and 2012. Of the 115 (25.6%) patients with SSI defined by the CDC guideline, 89 could be analyzed. We compared the SSI rates and severity defined by the CDC guideline and Clavien-Dindo classifications. There were 58 patients with superficial SSI, 16 with deep SSI, and 15 with organ/space SSI according to the CDC guideline. All patients with organ/space SSI were judged as "not having SSI" by the Clavien-Dindo classification. They were classified as having "intestinal prolapse", "intestinal fistula", "abdominal abscess" and "pelvic abscess." There was a significant association between the treatment duration and depth of SSI based on the CDC guideline by Spearman's rank-correlation coefficient (p < 0.001, r = 0.614) and with the grade of complications (p < 0.001, r = 0.632) in the Clavien-Dindo classification. Multivariate analysis showed that patients with grade III SSI in the Clavien-Dindo classification needed a significantly longer treatment duration. It is necessary to be aware that a discrepancy can occur automatically due to the different natures of the definitions. Using the CDC guideline, we can effectively estimate the future treatment period when SSI occurs. With the Clavien-Dindo classification, grade III SSI requires a longer treatment duration. Copyright © 2014 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

Post-discharge surgical site infections after uncomplicated elective colorectal surgery: impact and risk factors. The experience of the VINCat Program.

PubMed

Limón, E; Shaw, E; Badia, J M; Piriz, M; Escofet, R; Gudiol, F; Pujol, M

2014-02-01

Surgical site infection (SSI) after colorectal procedures represents a measurable quality indicator of a healthcare system. There is an increasing interest in comparing SSI rates between different hospitals and countries: however, the variability of the data regarding the incidence of SSI makes this comparison difficult. For the purposes of evaluation, data collection must be standardized and must include reliable post-discharge surveillance (PDS). To determine impact and risk factors for PDS SSI after elective colorectal surgery. VINCat is a nosocomial infection surveillance programme in Catalonia, Spain. Between 2007 and 2011, 52 hospitals joined the programme. Hospitals performed active, prospective, standardized surveillance of elective colorectal resection. PDS was implemented by a multimodal approach and was mandatory within the first 30 days after surgery. During the study period, 13,661 elective colorectal procedures were included. SSI was diagnosed in 2826 (20.7%) patients, of whom 22.5% during PDS; of these, 52% required readmission. Patients with PDS SSI were younger (odds ratio: 1.57; 95% confidence interval: 1.29-1.91), predominantly female (1.40; 1.16-1.69), had more frequently undergone endoscopic procedures (1.56; 1.30-1.88) and had more incisional SSI (1.88; 1.54-2.28) than patients with in-hospital SSI. SSI rates in elective colorectal procedures at VINCat hospitals were inside the higher range of those reported by other national programmes. PDS SSI increased the overall rate of SSI, had a significant clinical impact, and accounted for almost a quarter of SSI. Younger age and laparoscopic procedures were the most relevant risk factors. Standardized multimodal PDS should be implemented for hospitals performing surveillance of colorectal surgery. Copyright © 2013 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

Modelling Solar and Stellar Brightness Variabilities

NASA Astrophysics Data System (ADS)

Yeo, K. L.; Shapiro, A. I.; Krivova, N. A.; Solanki, S. K.

2016-04-01

Total and spectral solar irradiance, TSI and SSI, have been measured from space since 1978. This is accompanied by the development of models aimed at replicating the observed variability by relating it to solar surface magnetism. Despite significant progress, there remains persisting controversy over the secular change and the wavelength-dependence of the variation with impact on our understanding of the Sun's influence on the Earth's climate. We highlight the recent progress in TSI and SSI modelling with SATIRE. Brightness variations have also been observed for Sun-like stars. Their analysis can profit from knowledge of the solar case and provide additional constraints for solar modelling. We discuss the recent effort to extend SATIRE to Sun-like stars.

Failure of Colorectal Surgical Site Infection Predictive Models Applied to an Independent Dataset: Do They Add Value or Just Confusion?

PubMed

Bergquist, John R; Thiels, Cornelius A; Etzioni, David A; Habermann, Elizabeth B; Cima, Robert R

2016-04-01

Colorectal surgical site infections (C-SSIs) are a major source of postoperative morbidity. Institutional C-SSI rates are modeled and scrutinized, and there is increasing movement in the direction of public reporting. External validation of C-SSI risk prediction models is lacking. Factors governing C-SSI occurrence are complicated and multifactorial. We hypothesized that existing C-SSI prediction models have limited ability to accurately predict C-SSI in independent data. Colorectal resections identified from our institutional ACS-NSQIP dataset (2006 to 2014) were reviewed. The primary outcome was any C-SSI according to the ACS-NSQIP definition. Emergency cases were excluded. Published C-SSI risk scores: the National Nosocomial Infection Surveillance (NNIS), Contamination, Obesity, Laparotomy, and American Society of Anesthesiologists (ASA) class (COLA), Preventie Ziekenhuisinfecties door Surveillance (PREZIES), and NSQIP-based models were compared with receiver operating characteristic (ROC) analysis to evaluate discriminatory quality. There were 2,376 cases included, with an overall C-SSI rate of 9% (213 cases). None of the models produced reliable and high quality C-SSI predictions. For any C-SSI, the NNIS c-index was 0.57 vs 0.61 for COLA, 0.58 for PREZIES, and 0.62 for NSQIP: all well below the minimum "reasonably" predictive c-index of 0.7. Predictions for superficial, deep, and organ space SSI were similarly poor. Published C-SSI risk prediction models do not accurately predict C-SSI in our independent institutional dataset. Application of externally developed prediction models to any individual practice must be validated or modified to account for institution and case-mix specific factors. This questions the validity of using externally or nationally developed models for "expected" outcomes and interhospital comparisons. Copyright © 2016 American College of Surgeons. Published by Elsevier Inc. All rights reserved.

Reduction of medication errors related to sliding scale insulin by the introduction of a standardized order sheet.

PubMed

Harada, Saki; Suzuki, Akio; Nishida, Shohei; Kobayashi, Ryo; Tamai, Sayuri; Kumada, Keisuke; Murakami, Nobuo; Itoh, Yoshinori

2017-06-01

Insulin is frequently used for glycemic control. Medication errors related to insulin are a common problem for medical institutions. Here, we prepared a standardized sliding scale insulin (SSI) order sheet and assessed the effect of its introduction. Observations before and after the introduction of the standardized SSI template were conducted at Gifu University Hospital. The incidence of medication errors, hyperglycemia, and hypoglycemia related to SSI were obtained from the electronic medical records. The introduction of the standardized SSI order sheet significantly reduced the incidence of medication errors related to SSI compared with that prior to its introduction (12/165 [7.3%] vs 4/159 [2.1%], P = .048). However, the incidence of hyperglycemia (≥250 mg/dL) and hypoglycemia (≤50 mg/dL) in patients who received SSI was not significantly different between the 2 groups. The introduction of the standardized SSI order sheet reduced the incidence of medication errors related to SSI. © 2016 John Wiley & Sons, Ltd.

Controlled color photomosaic map of Ganymede Jg 15M CMNK

USGS Publications Warehouse

,

2003-01-01

This sheet is one in a series of maps of the Galilean satellites of Jupiter at a nominal scale of 1:15,000,000. This series is based on data from the Galileo Orbiter Solid-State Imaging (SSI) camera and the Voyager 1 and 2 spacecraft.

20 CFR 416.2097 - Combined supplementary/SSI payment levels.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Combined supplementary/SSI payment levels... Combined supplementary/SSI payment levels. (a) Other than the level for residents of Medicaid facilities (see paragraph (d) of this section), the combined supplementary/SSI payment level for each payment...

Proposal for a sub-classification of hepato-biliary-pancreatic operations for surgical site infection surveillance following assessment of results of prospective multicenter data.

PubMed

Nakahira, Shin; Shimizu, Junzo; Miyamoto, Atsushi; Kobayashi, Shogo; Umeshita, Koji; Ito, Toshinori; Monden, Morito; Doki, Yuichiro; Mori, Masaki

2013-06-01

Surgical site infection (SSI) surveillance in Japan is based on the National Nosocomial Infection Surveillance system, which categorizes all hepato-biliary-pancreatic surgeries, except for cholecystectomy, into "BILI." We evaluated differences among BILI procedures to determine the optimal subdivision for SSI surveillance. We conducted multicenter SSI surveillance at 20 hospitals. BILI was subdivided into choledochectomy, pancreatoduodenectomy, hepatectomy, hepatectomy with biliary reconstruction, pancreatoduodenectomy with hepatectomy, distal pancreatectomy and total pancreatectomy to determine the optimal subdivision. The outcome of interest was SSI. Univariate and multivariate analyses were performed to determine the predictive significance of variables in each type of surgery. 1,926 BILI cases were included in this study. SSI rates were 23.2 % for all BILI; for choledochectomy 23.6 %, pancreatoduodenectomy 39.3 %, hepatectomy 12.8 %, hepatectomy with biliary reconstruction 41.9 %, pancreatoduodenectomy with hepatectomy 27.3 %, distal pancreatectomy 31.8 %, and total pancreatectomy 20.0 %. SSI rates for hepatectomy were significantly lower than those for non-hepatectomy BILI. Risk factors for developing SSI with hepatectomy were drain placement and long operative duration, while for non-hepatectomy BILI, risk factors were use of intra-abdominal silk sutures, SSI risk index and long operative duration. Hepatectomy and non-hepatectomy BILI differ with regard to the incidence of and risk factors for developing SSI. These surgeries should be assessed separately when conducting SSI surveillance.

Sectoral contributions to surface water stress in the coterminous United States

Treesearch

K. Averyt; J. Meldrum; P. Caldwell; G. Sun; S. McNulty; A. Huber-Lee; N. Madden

2013-01-01

Here, we assess current stress in the freshwater system based on the best available data in order to understand possible risks and vulnerabilities to regional water resources and the sectors dependent on freshwater. We present watershed-scale measures of surface water supply stress for the coterminous United States (US) using the water supply stress index (WaSSI) model...

Synthesis and improved SERS performance of silver nanoparticles-decorated surface mesoporous silica microspheres

NASA Astrophysics Data System (ADS)

Jiang, Tao; Wang, Xiaolong; Zhang, Li; Zhou, Jun; Zhao, Ziqi

2016-08-01

This study reported the improved Raman enhancement ability of silver nanoparticles (Ag NPs) decorated on surface mesoporous silica microspheres (MSiO2@Ag) than that of Ag NPs on solid silica microspheres (SSiO2@Ag). These two kinds of hybrid structures were prepared by a facile single-step hydrothermal reaction with polyvinylpyrrolidone (PVP) serves as both a reductant and stabilizer. The as-synthesized MSiO2@Ag microspheres show more significant surface-enhanced Raman scattering (SERS) activity for 4-mercaptobenzoic acid (4MBA) than SSiO2@Ag microspheres with enhancement factors as 9.20 × 106 and 4.39 × 106, respectively. The proposed reason for the higher SERS activity is estimated to be the contribution of more Raman probe molecules at the mesoporous channels where an enhanced electromagnetic field exists. Such a field was identified by theoretical calculation result. The MSiO2@Ag microspheres were eventually demonstrated for the SERS detection of a typical chemical toxin namely methyl parathion with a detection limit as low as 1 × 10-3 ppm, showing its promising potential in biosensor application.

Environmental factors controlling spatial variation in sediment yield in a central Andean mountain area

NASA Astrophysics Data System (ADS)

Molina, Armando; Govers, Gerard; Poesen, Jean; Van Hemelryck, Hendrik; De Bièvre, Bert; Vanacker, Veerle

2008-06-01

A large spatial variability in sediment yield was observed from small streams in the Ecuadorian Andes. The objective of this study was to analyze the environmental factors controlling these variations in sediment yield in the Paute basin, Ecuador. Sediment yield data were calculated based on sediment volumes accumulated behind checkdams for 37 small catchments. Mean annual specific sediment yield (SSY) shows a large spatial variability and ranges between 26 and 15,100 Mg km - 2 year - 1 . Mean vegetation cover (C, fraction) in the catchment, i.e. the plant cover at or near the surface, exerts a first order control on sediment yield. The fractional vegetation cover alone explains 57% of the observed variance in ln(SSY). The negative exponential relation (SSY = a × e- b C) which was found between vegetation cover and sediment yield at the catchment scale (10 3-10 9 m 2), is very similar to the equations derived from splash, interrill and rill erosion experiments at the plot scale (1-10 3 m 2). This affirms the general character of an exponential decrease of sediment yield with increasing vegetation cover at a wide range of spatial scales, provided the distribution of cover can be considered to be essentially random. Lithology also significantly affects the sediment yield, and explains an additional 23% of the observed variance in ln(SSY). Based on these two catchment parameters, a multiple regression model was built. This empirical regression model already explains more than 75% of the total variance in the mean annual sediment yield. These results highlight the large potential of revegetation programs for controlling sediment yield. They show that a slight increase in the overall fractional vegetation cover of degraded land is likely to have a large effect on sediment production and delivery. Moreover, they point to the importance of detailed surface vegetation data for predicting and modeling sediment production rates.

[Surveillance of surgical-site infections: results of the INCISO 1998 Network].

PubMed

Golliot, F; Astagneau, P; Brücker, G

1999-01-01

Surveillance of Surgical-Site Infection (SSI) in general and visceral surgical departments. Prospective cohort study. Inter-regional Co-ordinating Center for Nosocomial Infection Control (C.CLIN Paris-Nord). Regions of Ile de France, Haute Normandie, Nord-Pas de Calais and Picardie. From January 1 to April 1, 1998, each surgical department had included 200 consecutive operations. To diagnose SSI occurring after discharge, patients were followed during one month after surgery. SSI were defined according to standardized criteria. Overall, 16.506 surgeries were followed in 120 surgical units. The rate of postoperative SSI was 3.9% (95CI = [3.6%-4.2%]). The rate of SSI varied from 5.2% for digestive surgery to 0.9% for endocrine system, and 2.3% for cholecystectomy to 16.6% for peritonitis. According to the NNIS index, SSI rates increased from 2.2% for patients with a risk index of 0 to 26.7% for patients with a risk index of 3. The case fatality rate directly or indirectly attributable to SSI was 2.0% (95CI = [1.1%-3.5%]). The high incidence of SSI render crucial the implementation of SSI surveillance in surgery. Risk factors and type of surgical procedures are required to obtain standardized rates for comparisons between services.

Psychometric properties and clinical utility of the Scale for Suicidal Ideation (SSI) in adolescents

PubMed Central

Holi, Matti M; Pelkonen, Mirjami; Karlsson, Linnea; Kiviruusu, Olli; Ruuttu, Titta; Heilä, Hannele; Tuisku, Virpi; Marttunen, Mauri

2005-01-01

Background Accurate assessment of suicidality is of major importance in both clinical and research settings. The Scale for Suicidal Ideation (SSI) is a well-established clinician-rating scale but its suitability to adolescents has not been studied. The aim of this study was to evaluate the reliability and validity, and to test an appropriate cutoff threshold for the SSI in a depressed adolescent outpatient population and controls. Methods 218 adolescent psychiatric outpatient clinic patients suffering from depressive disorders and 200 age- and sex-matched school-attending controls were evaluated by the SSI for presence and severity of suicidal ideation. Internal consistency, discriminative-, concurrent-, and construct validity as well as the screening properties of the SSI were evaluated. Results Cronbach's α for the whole SSI was 0.95. The SSI total score differentiated patients and controls, and increased statistically significantly in classes with increasing severity of suicidality derived from the suicidality items of the K-SADS-PL diagnostic interview. Varimax-rotated principal component analysis of the SSI items yielded three theoretically coherent factors suggesting construct validity. Area under the receiver operating characteristic (ROC) curve was 0.84 for the whole sample and 0.80 for the patient sample. The optimal cutoff threshold for the SSI total score was 3/4 yielding sensitivity of 75% and specificity of 88.9% in this population. Conclusions SSI appears to be a reliable and a valid measure of suicidal ideation for depressed adolescents. PMID:15691388

Psychometric properties and clinical utility of the Scale for Suicidal Ideation (SSI) in adolescents.

PubMed

Holi, Matti M; Pelkonen, Mirjami; Karlsson, Linnea; Kiviruusu, Olli; Ruuttu, Titta; Heilä, Hannele; Tuisku, Virpi; Marttunen, Mauri

2005-02-03

Accurate assessment of suicidality is of major importance in both clinical and research settings. The Scale for Suicidal Ideation (SSI) is a well-established clinician-rating scale but its suitability to adolescents has not been studied. The aim of this study was to evaluate the reliability and validity, and to test an appropriate cutoff threshold for the SSI in a depressed adolescent outpatient population and controls. 218 adolescent psychiatric outpatient clinic patients suffering from depressive disorders and 200 age- and sex-matched school-attending controls were evaluated by the SSI for presence and severity of suicidal ideation. Internal consistency, discriminative-, concurrent-, and construct validity as well as the screening properties of the SSI were evaluated. Cronbach's alpha for the whole SSI was 0.95. The SSI total score differentiated patients and controls, and increased statistically significantly in classes with increasing severity of suicidality derived from the suicidality items of the K-SADS-PL diagnostic interview. Varimax-rotated principal component analysis of the SSI items yielded three theoretically coherent factors suggesting construct validity. Area under the receiver operating characteristic (ROC) curve was 0.84 for the whole sample and 0.80 for the patient sample. The optimal cutoff threshold for the SSI total score was 3/4 yielding sensitivity of 75% and specificity of 88.9% in this population. SSI appears to be a reliable and a valid measure of suicidal ideation for depressed adolescents.

Reduced Ssy1-Ptr3-Ssy5 (SPS) signaling extends replicative life span by enhancing NAD+ homeostasis in Saccharomyces cerevisiae.

PubMed

Tsang, Felicia; James, Christol; Kato, Michiko; Myers, Victoria; Ilyas, Irtqa; Tsang, Matthew; Lin, Su-Ju

2015-05-15

Attenuated nutrient signaling extends the life span in yeast and higher eukaryotes; however, the mechanisms are not completely understood. Here we identify the Ssy1-Ptr3-Ssy5 (SPS) amino acid sensing pathway as a novel longevity factor. A null mutation of SSY5 (ssy5Δ) increases replicative life span (RLS) by ∼50%. Our results demonstrate that several NAD(+) homeostasis factors play key roles in this life span extension. First, expression of the putative malate-pyruvate NADH shuttle increases in ssy5Δ cells, and deleting components of this shuttle, MAE1 and OAC1, largely abolishes RLS extension. Next, we show that Stp1, a transcription factor of the SPS pathway, directly binds to the promoter of MAE1 and OAC1 to regulate their expression. Additionally, deletion of SSY5 increases nicotinamide riboside (NR) levels and phosphate-responsive (PHO) signaling activity, suggesting that ssy5Δ increases NR salvaging. This increase contributes to NAD(+) homeostasis, partially ameliorating the NAD(+) deficiency and rescuing the short life span of the npt1Δ mutant. Moreover, we observed that vacuolar phosphatase, Pho8, is partially required for ssy5Δ-mediated NR increase and RLS extension. Together, our studies present evidence that supports SPS signaling is a novel NAD(+) homeostasis factor and ssy5Δ-mediated life span extension is likely due to concomitantly increased mitochondrial and vacuolar function. Our findings may contribute to understanding the molecular basis of NAD(+) metabolism, cellular life span, and diseases associated with NAD(+) deficiency and aging. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

Surgical site infections: reanalysis of risk factors.

PubMed

Malone, Debra L; Genuit, Thomas; Tracy, J Kathleen; Gannon, Christopher; Napolitano, Lena M

2002-03-01

Surgical site infections (SSI) are the most common nosocomial infection in surgical patients, accounting for 38% of all such infections, and are a significant source of postoperative morbidity resulting in increased hospital length of stay and increased cost. During 1986-1996 the Center for Disease Control and Prevention's National Nosocomial Infections Surveillance system reported 15,523 SSI following 593,344 operations (2.6%). Previous studies have documented patient characteristics associated with an increased risk of SSI, including diabetes, tobacco or steroid use, obesity, malnutrition, and perioperative blood transfusion. In this study we sought to reevaluate risk factors for SSI in a large cohort of noncardiac surgical patients. Prospective data (NSQIP) were collected on 5031 noncardiac surgical patients at the Veteran's Administration Maryland Healthcare System from 1995 to 2000. All preoperative risk factors were evaluated as independent predictors of surgical site infection. The mean age of the study cohort was 61 plus minus 13. SSI occurred in 162 patients, comprising 3.2% of the study cohort. Gram-positive organisms were the most common bacterial etiology. Multiple logistic regression analysis documented that diabetes (insulin- and non-insulin-dependent), low postoperative hematocrit, weight loss (within 6 months), and ascites were significantly associated with increased SSI. Tobacco use, steroid use, and chronic obstructive pulmonary disease (COPD) were not predictors for SSI. This study confirms that diabetes and malnutrition (defined as significant weight loss 6 months prior to surgery) are significant preoperative risk factors for SSI. Postoperative anemia is a significant risk factor for SSI. In contrast to prior analyses, this study has documented that tobacco use, steroid use, and COPD are not independent predictors of SSI. Future SSI studies should target early preoperative intervention and optimization of patients with diabetes and malnutrition.

Suppression of the rice fatty-acid desaturase gene OsSSI2 enhances resistance to blast and leaf blight diseases in rice.

PubMed

Jiang, Chang-Jie; Shimono, Masaki; Maeda, Satoru; Inoue, Haruhiko; Mori, Masaki; Hasegawa, Morifumi; Sugano, Shoji; Takatsuji, Hiroshi

2009-07-01

Fatty acids and their derivatives play important signaling roles in plant defense responses. It has been shown that suppressing a gene for stearoyl acyl carrier protein fatty-acid desaturase (SACPD) enhances the resistance of Arabidopsis (SSI2) and soybean to multiple pathogens. In this study, we present functional analyses of a rice homolog of SSI2 (OsSSI2) in disease resistance of rice plants. A transposon insertion mutation (Osssi2-Tos17) and RNAi-mediated knockdown of OsSSI2 (OsSSI2-kd) reduced the oleic acid (18:1) level and increased that of stearic acid (18:0), indicating that OsSSI2 is responsible for fatty-acid desaturase activity. These plants displayed spontaneous lesion formation in leaf blades, retarded growth, slight increase in endogenous free salicylic acid (SA) levels, and SA/benzothiadiazole (BTH)-specific inducible genes, including WRKY45, a key regulator of SA/BTH-induced resistance, in rice. Moreover, the OsSSI2-kd plants showed markedly enhanced resistance to the blast fungus Magnaporthe grisea and leaf-blight bacteria Xanthomonas oryzae pv. oryzae. These results suggest that OsSSI2 is involved in the negative regulation of defense responses in rice, as are its Arabidopsis and soybean counterparts. Microarray analyses identified 406 genes that were differentially expressed (>or=2-fold) in OsSSI2-kd rice plants compared with wild-type rice and, of these, approximately 39% were BTH responsive. Taken together, our results suggest that induction of SA-responsive genes, including WRKY45, is likely responsible for enhanced disease resistance in OsSSI2-kd rice plants.

Neuropsychiatric subsyndromes and brain metabolic network dysfunctions in early onset Alzheimer's disease.

PubMed

Ballarini, Tommaso; Iaccarino, Leonardo; Magnani, Giuseppe; Ayakta, Nagehan; Miller, Bruce L; Jagust, William J; Gorno-Tempini, Maria Luisa; Rabinovici, Gil D; Perani, Daniela

2016-12-01

Neuropsychiatric symptoms (NPSs) often occur in early-age-of-onset Alzheimer's disease (EOAD) and cluster into sub-syndromes (SSy). The aim of this study was to investigate the association between 18 F-FDG-PET regional and connectivity-based brain metabolic dysfunctions and neuropsychiatric SSy. NPSs were assessed in 27 EOAD using the Neuropsychiatric Inventory and further clustered into four SSy (apathetic, hyperactivity, affective, and psychotic SSy). Eighty-five percent of EOAD showed at least one NPS. Voxel-wise correlations between SSy scores and brain glucose metabolism (assessed with 18 F-FDG positron emission tomography) were studied. Interregional correlation analysis was used to explore metabolic connectivity in the salience (aSN) and default mode networks (DMN) in a larger sample of EOAD (N = 51) and Healthy Controls (N = 57). The apathetic, hyperactivity, and affective SSy were highly prevalent (>60%) as compared to the psychotic SSy (33%). The hyperactivity SSy scores were associated with increase of glucose metabolism in frontal and limbic structures, implicated in behavioral control. A comparable positive correlation with part of the same network was found for the affective SSy scores. On the other hand, the apathetic SSy scores were negatively correlated with metabolism in the bilateral orbitofrontal and dorsolateral frontal cortex known to be involved in motivation and decision-making processes. Consistent with these SSy regional correlations with brain metabolic dysfunction, the connectivity analysis showed increases in the aSN and decreases in the DMN. Behavioral abnormalities in EOAD are associated with specific dysfunctional changes in brain metabolic activity, in particular in the aSN that seems to play a crucial role in NPSs in EOAD. Hum Brain Mapp 37:4234-4247, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Neuropsychiatric Subsyndromes and Brain Metabolic Network Dysfunctions in Early Onset Alzheimer’s Disease

PubMed Central

Tommaso, Ballarini; Leonardo, Iaccarino; Giuseppe, Magnani; Nagehan, Ayakta; Bruce L, Miller; William J, Jagust; Luisa, Gorno-Tempini Maria; Gil D, Rabinovici; Daniela, Perani

2017-01-01

Neuropsychiatric symptoms (NPSs) often occur in early-age-of-onset Alzheimer’s disease (EOAD) and cluster into sub-syndromes (SSy). The aim of this study was to investigate the association between 18F-FDG-PET regional and connectivity-based brain metabolic dysfunctions and neuropsychiatric SSy. NPSs were assessed in 27 EOAD using the Neuropsychiatric Inventory and further clustered into four SSy (apathetic, hyperactivity, affective and psychotic SSy). 85% of EOAD showed at least one NPS. Voxel-wise correlations between SSy scores and brain glucose metabolism (assessed with 18F-FDG positron emission tomography) were studied. Interregional correlation analysis was used to explore metabolic connectivity in the salience (aSN) and default mode networks (DMN) in a larger sample of EOAD (N=51) and Healthy Controls (N=57). The apathetic, hyperactivity and affective SSy were highly prevalent (>60%) as compared to the psychotic SSy (33%). The hyperactivity SSy scores were associated with increase of glucose metabolism in frontal and limbic structures, implicated in behavioral control. A comparable positive correlation with part of the same network was found for the affective SSy scores. On the other hand, the apathetic SSy scores were negatively correlated with metabolism in the bilateral orbitofrontal and dorsolateral frontal cortex known to be involved in motivation and decision-making processes. Consistent with these SSy regional correlations with brain metabolic dysfunction, the connectivity analysis showed increases in the aSN and decreases in the DMN. Behavioral abnormalities in EOAD are associated with specific dysfunctional changes in brain metabolic activity, in particular in the aSN that seems to play a crucial role in NPSs in EOAD. PMID:27412866

Does an information leaflet about surgical site infection (SSI) improve recollection of information and satisfaction of patients? A randomized trial in patients scheduled for digestive surgery.

PubMed

Merle, Véronique; Marini, Hélène; Rongère, Julie; Tavolacci, Marie-Pierre; Scotté, Michel; Czernichow, Pierre

2011-06-01

A previous study suggested that most surgical patients do not remember having received information about surgical site infection (SSI). In other fields, written information has been suggested to improve patient satisfaction and recollection of information. Our objective was to assess if providing patients with written information about SSI, in addition to oral information, could influence patient satisfaction, recall of information, and opinion regarding SSI. A total of 207 patients scheduled for digestive surgery at a university hospital were randomized between usual oral information about SSI, plus an information leaflet about SSI (group O/L), or usual oral information alone (group O). Patients were interviewed 5 weeks after surgery to assess their recall and satisfaction regarding information, opinion regarding SSI, and declared intention of seeking legal action in case of SSI. Surgeons and interviewer were blinded to patients' group allocation. Recruitment occurred between October 2005 and August 2006. Of the original 207 patients, 161 patients (O/L=87, O=74) underwent operation and were interviewed as scheduled. Satisfaction was higher in group O/L (67% vs. O: 43%; P=0.003). The recall of having received information (O/L: 39% vs. O: 31%; P=0.29), was similar between the two groups. Judging SSI as always preventable was more frequent in group O/L (28% vs. O: 9%; P=0.004) with a trend toward a more frequent intention of seeking legal action (O/L: 10% vs. O: 3%; P=0.055). The leaflet did not improve patient recall of information about SSI, but it was associated with an increased level of satisfaction. The association between the leaflet and judging SSI as always preventable was unexpected.

A new method for assessing surface solar irradiance: Heliosat-4

NASA Astrophysics Data System (ADS)

Qu, Z.; Oumbe, A.; Blanc, P.; Lefèvre, M.; Wald, L.; Schroedter-Homscheidt, M.; Gesell, G.

2012-04-01

Downwelling shortwave irradiance at surface (SSI) is more and more often assessed by means of satellite-derived estimates of optical properties of the atmosphere. Performances are judged satisfactory for the time being but there is an increasing need for the assessment of the direct and diffuse components of the SSI. MINES ParisTech and the German Aerospace Center (DLR) are currently developing the Heliosat-4 method to assess the SSI and its components in a more accurate way than current practices. This method is composed by two parts: a clear sky module based on the radiative transfer model libRadtran, and a cloud-ground module using two-stream and delta-Eddington approximations for clouds and a database of ground albedo. Advanced products derived from geostationary satellites and recent Earth Observation missions are the inputs of the Heliosat-4 method. Such products are: cloud optical depth, cloud phase, cloud type and cloud coverage from APOLLO of DLR, aerosol optical depth, aerosol type, water vapor in clear-sky, ozone from MACC products (FP7), and ground albedo from MODIS of NASA. In this communication, we briefly present Heliosat-4 and focus on its performances. The results of Heliosat-4 for the period 2004-2010 will be compared to the measurements made in five stations within the Baseline Surface Radiation Network. Extensive statistic analysis as well as case studies are performed in order to better understand Heliosat-4 and have an in-depth view of the performance of Heliosat-4, to understand its advantages comparing to existing methods and to identify its defaults for future improvements. The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under Grant Agreement no. 218793 (MACC project) and no. 283576 (MACC-II project).

Intrawound Vancomycin Decreases the Risk of Surgical Site Infection After Posterior Spine Surgery: A Multicenter Analysis.

PubMed

Devin, Clinton J; Chotai, Silky; McGirt, Matthew J; Vaccaro, Alexander R; Youssef, Jim A; Orndorff, Douglas G; Arnold, Paul M; Frempong-Boadu, Anthony K; Lieberman, Isador H; Branch, Charles; Hedayat, Hirad S; Liu, Ann; Wang, Jeffrey C; Isaacs, Robert E; Radcliff, Kris E; Patt, Joshua C; Archer, Kristin R

2018-01-01

Secondary analysis of data from a prospective multicenter observational study. The aim of this study was to evaluate the occurrence of surgical site infection (SSI) in patients with and without intrawound vancomycin application controlling for confounding factors associated with higher SSI after elective spine surgery. SSI is a morbid and expensive complication associated with spine surgery. The application of intrawound vancomycin is rapidly emerging as a solution to reduce SSI following spine surgery. The impact of intrawound vancomycin has not been systematically studied in a well-designed multicenter study. Patients undergoing elective spine surgery over a period of 4 years at seven spine surgery centers across the United States were included in the study. Patients were dichotomized on the basis of whether intrawound vancomycin was applied. Outcomes were occurrence of SSI within postoperative 30 days and SSI that required return to the operating room (OR). Multivariable random-effect log-binomial regression analyses were conducted to determine the relative risk of having an SSI and an SSI with return to OR. .: A total of 2056 patients were included in the analysis. Intrawound vancomycin was utilized in 47% (n = 966) of patients. The prevalence of SSI was higher in patients with no vancomycin use (5.1%) than those with use of intrawound vancomycin (2.2%). The risk of SSI was higher in patients in whom intrawound vancomycin was not used (relative risk (RR) -2.5, P < 0.001), increased number of levels exposed (RR -1.1, P = 0.01), and those admitted postoperatively to intensive care unit (ICU) (RR -2.1, P = 0.005). Patients in whom intrawound vancomycin was not used (RR -5.9, P < 0.001), increased number of levels were exposed (RR-1.1, P = 0.001), and postoperative ICU admission (RR -3.3, P < 0.001) were significant risk factors for SSI requiring a return to the OR. The intrawound application of vancomycin after posterior approach spine surgery was associated with a reduced risk of SSI and return to OR associated with SSI. 2.

College students' use of science content during socioscientific issues negotiation: Impact of evolution understanding and acceptance

NASA Astrophysics Data System (ADS)

Fowler, Samantha R.

The purpose of this study was to explore the evolution science content used during college students' negotiation of biology-based socioscientific issues (SSI) and examine how it related to students' conceptual understanding and acceptance of biological evolution. Specific research questions were, (1a) what specific evolutionary science content do college students evoke during SSI negotiation, (1b) what is the depth of the evolutionary science content reflected in college students. SSI negotiation, and (2) what is the nature of the interaction between evolution understanding and evolution acceptance as they relate to depth of use of evolution content during SSI negotiation? The Socioscientific Issues Questionnaire (SSI-Q) was developed using inductive data analysis to examine science content use and to develop a rubric for measuring depth of evolutionary science content use during SSI negotiation. Sixty upper level undergraduate biology and non-biology majors completed the SSI-Q and also the Conceptual Inventory of Natural Selection (CINS: Anderson, Fisher, & Norman, 2002) to measure evolution understanding and the Measure of Acceptance of the Theory of Evolution (MATE: Rutledge & Warden, 1999) to measure evolution acceptance. A multiple regression analysis tested for interaction effects between the predictor variables, evolution understanding and evolution acceptance. Results indicate that college students primarily use science concepts related to evolution to negotiate biology-based SSI: variation in a population, inheritance of traits, differential success, and change through time. The hypothesis that the extent of one's acceptance of evolution is a mitigating factor in how evolution content is evoked during SSI negotiation was supported by the data. This was seen in that evolution was the predominant science content used by participants for each of the three SSI scenarios used in this study and used consistently throughout the three SSI scenarios. In addition to its potential to assess aspects of argumentation, a modification of the SSI-Q could be used for further study about students' misconceptions about evolution or scientific literacy, if it is defined as one's tendency to utilize science content during a decision-making process within an SSI context.

Turkish preservice science teachers' socioscientific issues-based teaching practices in middle school science classrooms

NASA Astrophysics Data System (ADS)

Genel, Abdulkadir; Sami Topçu, Mustafa

2016-01-01

Background: Despite a growing body of research and curriculum reforms including socioscientific issues (SSI) across the world, how preservice science teachers (PST) or in-service science teachers can teach SSI in science classrooms needs further inquiry. Purpose: The purpose of this study is to describe the abilities of PSTs to teach SSI in middle school science classrooms, and the research question that guided the present study is: How can we characterize Turkish PSTs' SSI-based teaching practices in middle school science classrooms (ages 11-14)? Sample: In order to address the research question of this study, we explored 10 Turkish PSTs' SSI-based teaching practices in middle school science classrooms. A purposeful sampling strategy was used, thus, PSTs were specifically chosen because they were ideal candidates to teach SSI and to integrate SSI into the science curricula since they were seniors in the science education program who had to take the field experience courses. Design and method: The participants' SSI teaching practices were characterized in light of qualitative research approach. SSI-based teaching practices were analyzed, and the transcripts of all videotape recordings were coded by two researchers. Results: The current data analysis describes Turkish PSTs' SSI-based teaching practices under five main categories: media, argumentation, SSI selection and presentation, risk analysis, and moral perspective. Most of PSTs did not use media resources in their lesson and none of them considered moral perspective in their teaching. While the risk analyses were very simple and superficial, the arguments developed in the classrooms generally remained at a simple level. PSTs did not think SSI as a central topic and discussed these issues in a very limited time and at the end of the class period. Conclusions: The findings of this study manifest the need of the reforms in science education programs. The present study provides evidence that moral, media, argumentation, risk analysis, and pedagogical aspects of SSI-based instruction should be incorporated into educational courses designed for the Turkish teacher education programs such as the science teaching methods course. When we find ways to improve PSTs or science teachers' SSI teaching practices in terms of these components, we can provide useful information for curriculum developers, policy-makers, and science educators in Turkey and other countries, that are facing similar problems. We believe that this study would initiate more investigative and exploratory studies toward this goal.

The geologic history of the Galilean satellite Callisto. (Invited)

NASA Astrophysics Data System (ADS)

Wagner, R. J.; Neukum, G.; Wolf, U.; Greeley, R.

2009-12-01

Introduction: Callisto, the second-largest Galilean satellite of Jupiter, is a Mercury-sized icy moon with a diameter of 4816 km and an average density of 1.83 gcm-3. Despite its size the images returned by the Voyager cameras in two flybys in 1979 showed a densely cratered surface with little geologic diversity, in contrast to its neighbor Ganymede [1][2][3][4]. Between 1995 and 2003 the SSI camera aboard the Galileo spacecraft has extended but not completed the existing Voyager image data base of Callisto [2][3]. Geologic processes: Galileo SSI has shown that the two dominant geological processes are impact craters and surface degradation [2][3][4]. Abundant but less important are landforms created by tectonism, such as fractures and lineaments [1][2][3][4]. Surface ages are obtained by impact chronology models either with a lunar-like cratering rate, mostly by asteroids [5], or with a constant cratering rate, mostly by comets [6]. Geologic history: Various aspects of Callisto’s geologic history, based on Voyager and SSI data, were discussed in detail by [1][2][3][4]. Cratering chronology models [5][6] agree that Callisto’s densely cratered plains are mostly old, on the order of 4 Ga and older. The morphology of craters and basins is much like that on Ganymede, implying similar subsurface structure at the time of their formation. Palimpsests as on Ganymede occur, but most of them are heavily degraded and not easily recognizable. Callisto could have experienced an early period of heavy bombardment, as inferred from the lunar-like chronology model [5], and large impact structures (e.g., Valhalla, Lofn) could have formed towards its end, 3.8 - 4.0 Ga ago. All topographically high-standing landforms (e.g., crater rims) were affected by sublimation degradation, triggered by a substantial amount of CO2 in the icy crust [7]. Degradation started along pre-existing zones of weakness, caused by early tectonic stress. On-going sublimation and separation of highly volatile from less volatile materials created a globally abundant dark layer. It remains an unsolved question if degradation and the accumulation of dark material was going on at a fast rate during a time of heavy bombardment but went on at a considerably slow rate since 3.4 - 3.6 ago [4][5], or has continued at a constant rate until more recent times [4][6]. References: [1] Schenk, P. M. (1995), J. Geophys. Res. 100 (E9), 19,023 - 19,040. [2] Greeley, R. et al. (2000), Planet. Space Sci. 48, 829 - 853. [3] Moore, J. M. et al. (2004), in: Jupiter (F. Bagenal et al., eds.), Cambridge Planet. Sci., Vol. 1, p. 397 - 426. [4] Wagner R. (2007), PhD. Dissertation (in german), Free University of Berlin, Germany, http://www.diss.fu-berlin.de/2007/806. [5] Neukum G. et al. (1998), Lunar Planet. Sci. Conf. XXIX, abstr. #1992 [CD-Rom]. [6] Zahnle K. et al. (2003), Icarus 163, 263 - 289. [7] Moore J. M. et al. (1999), Icarus 140, 294 - 312.

20 CFR 416.202 - Who may get SSI benefits.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Who may get SSI benefits. 416.202 Section 416.202 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility General § 416.202 Who may get SSI benefits. You are eligible for SSI benefits if you meet all of the following...

Performance of shear wave elastography for differentiation of benign and malignant solid breast masses.

PubMed

Li, Guiling; Li, De-Wei; Fang, Yu-Xiao; Song, Yi-Jiang; Deng, Zhu-Jun; Gao, Jian; Xie, Yan; Yin, Tian-Sheng; Ying, Li; Tang, Kai-Fu

2013-01-01

To perform a meta-analysis assessing the ability of shear wave elastography (SWE) to identify malignant breast masses. PubMed, the Cochrane Library, and the ISI Web of Knowledge were searched for studies evaluating the accuracy of SWE for identifying malignant breast masses. The diagnostic accuracy of SWE was evaluated according to sensitivity, specificity, and hierarchical summary receiver operating characteristic (HSROC) curves. An analysis was also performed according to the SWE mode used: supersonic shear imaging (SSI) and the acoustic radiation force impulse (ARFI) technique. The clinical utility of SWE for identifying malignant breast masses was evaluated using analysis of Fagan plot. A total of 9 studies, including 1888 women and 2000 breast masses, were analyzed. Summary sensitivities and specificities were 0.91 (95% confidence interval [CI], 0.88-0.94) and 0.82 (95% CI, 0.75-0.87) by SSI and 0.89 (95% CI, 0.81-0.94) and 0.91 (95% CI, 0.84-0.95) by ARFI, respectively. The HSROCs for SSI and ARFI were 0.92 (95% CI, 0.90-0.94) and 0.96 (95% CI, 0.93-0.97), respectively. SSI and ARFI were both very informative, with probabilities of 83% and 91%, respectively, for correctly differentiating between benign and malignant breast masses following a "positive" measurement (over the threshold value) and probabilities of disease as low as 10% and 11%, respectively, following a "negative" measurement (below the threshold value) when the pre-test probability was 50%. SWE could be used as a good identification tool for the classification of breast masses.

Surface changes on Io during the Galileo mission

USGS Publications Warehouse

Geissler, P.; McEwen, A.; Phillips, C.; Keszthelyi, L.; Spencer, J.

2004-01-01

A careful survey of Galileo SSI global monitoring images revealed more than 80 apparent surface changes that took place on Io during the 5 year period of observation, ranging from giant plume deposits to subtle changes in the color or albedo of Patera surfaces. Explosive volcanic activity was discovered at four previously unrecognized centers: an unnamed patera to the south of Karei that produced a Pele-sized red ring, a patera to the west of Zal that produced a small circular bright deposit, a large orange ring detected near the north pole of Io, and a small bright ring near Io's south pole. Only a handful of Io's many active volcanoes produced large scale explosive eruptions, and several of these erupted repeatedly, leaving at least 83% of Io's surface unaltered throughout the Galileo mission. Most of the hot spots detected from SSI, NIMS and ground-based thermal observations caused no noticeable surface changes greater than 10 km in extent over the five year period. Surface changes were found at every location where active plumes were identified, including Acala which was never seen in sunlight and was only detected through auroral emissions during eclipse. Two types of plumes are distinguished on the basis of the size and color of their deposits, confirming post-Voyager suggestions by McEwen and Soderblom [Icarus 55 (1983) 191]. Smaller plumes produce near-circular rings typically 150-200 km in radius that are white or yellow in color unless contaminated with silicates, and frequently coat their surroundings with frosts of fine-grained SO2. The larger plumes are much less numerous, limited to a half dozen examples, and produce oval, orange or red, sulfur-rich rings with maximum radii in the north-south direction that are typically in the range from 500 to 550 km. Both types of plumes can be either episodic or quasi-continuous over a five year period. Repeated eruptions of the smaller SO2-rich plumes likely contribute significantly to Io's resurfacing rate, whereas dust ejection is likely dominated by the tenuous giant plumes. Both types of plume deposits fade on time-scales of months to years through burial and alteration. Episodic seepages of SO2 at Haemus Montes, Zal Montes, Dorian Montes, and the plateau to the north of Pillan Patera may have been triggered by activity at nearby volcanic centers. ?? 2003 Elsevier Inc. All rights reserved.

Surface Changes on Io during the Galileo Mission

NASA Astrophysics Data System (ADS)

Geissler, P.; McEwen, A.; Phillips, C.; Keszthelyi, L.; Spencer, J.

2003-04-01

A careful survey of Galileo SSI global monitoring images revealed more than 80 apparent surface changes that took place on Io during the 5 year period of observation, ranging from giant plume deposits to subtle changes in the color or albedo of patera surfaces. Explosive volcanic activity was discovered at four previously unrecognized centers: an un-named patera to the south of Karei that produced a Pele-sized red ring, a patera to the west of Zal that produced a small circular bright deposit, a large orange ring detected near the north pole of Io, and a small bright ring near Io's south pole. Only a handful of Io's many active volcanoes produced large scale explosive eruptions, and several of these erupted repeatedly, leaving at least 83% of Io's surface unaltered throughout the Galileo mission. Most of the hot spots detected from SSI, NIMS and groundbased thermal observations caused no noticeable surface changes greater than 10 km in extent over the five year period. Surface changes were found at every location where active plumes were identified, including Acala which was never seen in sunlight and was only detected through auroral emissions during eclipse. Two types of plumes are distinguished on the basis of the size and color of their deposits, confirming post-Voyager suggestions by McEwen and Soderblom (1983). Smaller plumes produce near-circular rings typically 150 to 200 km in radius that are white or yellow in color unless contaminated with silicates, and frequently coat their surroundings with frosts of fine-grained SO2. The larger plumes are much less numerous, limited to a half dozen examples, and produce oval, orange or red, sulfur- rich rings with maximum radii in the north-south direction that are typically in the range from 500 to 550 km. Both types of plumes can be either episodic or quasi-continuous over a five year period. Repeated eruptions of the smaller SO2-rich plumes likely contribute significantly to Io's resurfacing rate, whereas dust ejection is likely dominated by the tenuous giant plumes. Both types of plume deposits fade on time-scales of months to years through burial and alteration. Episodic seepages of SO2 at Haemus Montes, Zal Montes, Dorian Montes, and the plateau to the north of Pillan Patera may have been triggered by activity at nearby volcanic centers.

Surface changes on Io during the Galileo mission

NASA Astrophysics Data System (ADS)

Geissler, Paul; McEwen, Alfred; Phillips, Cynthia; Keszthelyi, Laszlo; Spencer, John

2004-05-01

A careful survey of Galileo SSI global monitoring images revealed more than 80 apparent surface changes that took place on Io during the 5 year period of observation, ranging from giant plume deposits to subtle changes in the color or albedo of patera surfaces. Explosive volcanic activity was discovered at four previously unrecognized centers: an unnamed patera to the south of Karei that produced a Pele-sized red ring, a patera to the west of Zal that produced a small circular bright deposit, a large orange ring detected near the north pole of Io, and a small bright ring near Io's south pole. Only a handful of Io's many active volcanoes produced large scale explosive eruptions, and several of these erupted repeatedly, leaving at least 83% of Io's surface unaltered throughout the Galileo mission. Most of the hot spots detected from SSI, NIMS and ground-based thermal observations caused no noticeable surface changes greater than 10 km in extent over the five year period. Surface changes were found at every location where active plumes were identified, including Acala which was never seen in sunlight and was only detected through auroral emissions during eclipse. Two types of plumes are distinguished on the basis of the size and color of their deposits, confirming post-Voyager suggestions by McEwen and Soderblom [Icarus 55 (1983) 191]. Smaller plumes produce near-circular rings typically 150-200 km in radius that are white or yellow in color unless contaminated with silicates, and frequently coat their surroundings with frosts of fine-grained SO 2. The larger plumes are much less numerous, limited to a half dozen examples, and produce oval, orange or red, sulfur-rich rings with maximum radii in the north-south direction that are typically in the range from 500 to 550 km. Both types of plumes can be either episodic or quasi-continuous over a five year period. Repeated eruptions of the smaller SO 2-rich plumes likely contribute significantly to Io's resurfacing rate, whereas dust ejection is likely dominated by the tenuous giant plumes. Both types of plume deposits fade on time-scales of months to years through burial and alteration. Episodic seepages of SO 2 at Haemus Montes, Zal Montes, Dorian Montes, and the plateau to the north of Pillan Patera may have been triggered by activity at nearby volcanic centers.

[Implementation of a post-discharge surgical site infection system in herniorrhaphy and mastectomy procedures].

PubMed

San Juan Sanz, Isabel; Díaz-Agero-Pérez, Cristina; Robustillo-Rodela, Ana; Pita López, María José; Oliva Iñiguez, Lourdes; Monge-Jodrá, Vicente

2014-10-01

Monitoring surgical site infection (SSI) performed during hospitalization can underestimate its rates due to the shortening in hospital stay. The aim of this study was to determine the actual rates of SSI using a post-discharge monitoring system. All patients who underwent herniorraphy or mastectomy in the Hospital Universitario Ramón y Cajal from 1 January 2011 to 31 December 2011 were included. SSI data were collected prospectively according to the continuous quality improvement indicators (Indicadores Clinicos de Mejora Continua de la Calidad [INCLIMECC]) monitoring system. Post-discharge follow-up was conducted by telephone survey. A total of 409patients were included in the study, of whom 299 underwent a herniorraphy procedure, and 110 underwent a mastectomy procedure. For herniorrhaphy, the SSI rate increased from 6.02% to 7.6% (the post-discharge survey detected 21.7% of SSI). For mastectomy, the SSI rate increased from 1.8% to 3.6% (the post-discharge survey detected 50% of SSI). Post-discharge monitoring showed an increased detection of SSI incidence. Post-discharge monitoring is useful to analyze the real trend of SSI, and evaluate improvement actions. Post-discharge follow-up methods need to standardised. Copyright © 2013 Elsevier España, S.L.U. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

GenSSI 2.0: multi-experiment structural identifiability analysis of SBML models.

PubMed

Ligon, Thomas S; Fröhlich, Fabian; Chis, Oana T; Banga, Julio R; Balsa-Canto, Eva; Hasenauer, Jan

2018-04-15

Mathematical modeling using ordinary differential equations is used in systems biology to improve the understanding of dynamic biological processes. The parameters of ordinary differential equation models are usually estimated from experimental data. To analyze a priori the uniqueness of the solution of the estimation problem, structural identifiability analysis methods have been developed. We introduce GenSSI 2.0, an advancement of the software toolbox GenSSI (Generating Series for testing Structural Identifiability). GenSSI 2.0 is the first toolbox for structural identifiability analysis to implement Systems Biology Markup Language import, state/parameter transformations and multi-experiment structural identifiability analysis. In addition, GenSSI 2.0 supports a range of MATLAB versions and is computationally more efficient than its previous version, enabling the analysis of more complex models. GenSSI 2.0 is an open-source MATLAB toolbox and available at https://github.com/genssi-developer/GenSSI. thomas.ligon@physik.uni-muenchen.de or jan.hasenauer@helmholtz-muenchen.de. Supplementary data are available at Bioinformatics online.

Morbidity associated with 30-day surgical site infection following nonshunt pediatric neurosurgery

PubMed Central

Sherrod, Brandon A.; Rocque, Brandon G.

2017-01-01

Objective Morbidity associated with surgical site infection (SSI) following nonshunt pediatric neurosurgical procedures is poorly understood. The purpose of this study was to analyze acute morbidity and mortality associated with SSI after nonshunt pediatric neurosurgery using a nationwide cohort. Methods The authors reviewed data from the American College of Surgeons National Surgical Quality Improvement Program Pediatric (NSQIP-P) 2012–2014 database, including all neurosurgical procedures performed on pediatric patients. Procedures were categorized by Current Procedural Terminology (CPT) codes. CSF shunts were excluded. Deep and superficial SSIs occurring within 30 days of an index procedure were identified. Deep SSIs included deep wound infections, intracranial abscesses, meningitis, osteomyelitis, and ventriculitis. The following outcomes occurring within 30 days of an index procedure were analyzed, along with postoperative time to complication development: sepsis, wound disruption, length of postoperative stay, readmission, reoperation, and death. Results A total of 251 procedures associated with a 30-day SSI were identified (2.7% of 9296 procedures). Superficial SSIs were more common than deep SSIs (57.4% versus 42.6%). Deep SSIs occurred more frequently after epilepsy or intracranial tumor procedures. Superficial SSIs occurred more frequently after skin lesion, spine, Chiari decompression, craniofacial, and myelomeningocele closure procedures. The mean (± SD) postoperative length of stay for patients with any SSI was 9.6 ± 14.8 days (median 4 days). Post-SSI outcomes significantly associated with previous SSI included wound disruption (12.4%), sepsis (15.5%), readmission (36.7%), and reoperation (43.4%) (p < 0.001 for each). Post-SSI sepsis rates (6.3% vs 28.0% for superficial versus deep SSI, respectively; p < 0.001), wound disruption rates (4.9% vs 22.4%, p < 0.001), and reoperation rates (23.6% vs 70.1%, p < 0.001) were significantly greater for patients with deep SSIs. Postoperative length of stay in patients discharged before SSI development was not significantly different for deep versus superficial SSI (4.2 ± 2.7 vs 3.6 ± 2.4 days, p = 0.094). No patient with SSI died within the first 30 days after surgery. Conclusions Thirty-day SSI is associated with significant 30-day morbidity in pediatric patients undergoing nonshunt neurosurgery. Rates of SSI-associated complications are significantly lower in patients with superficial infection than in those with deep infection. There were no cases of SSI-related mortality within 30 days of the index procedure. PMID:28186474

The TANF/SSI connection.

PubMed

Wamhoff, Steve; Wiseman, Michael

Interactions and overlap of social assistance programs across clients interest policymakers because such interactions affect both the clients' well-being and the programs' efficiency. This article investigates the connections between Supplemental Security Income (SSI) and Temporary Assistance for Needy Families (TANF) and TANF's predecessor, the Aid to Families with Dependent Children (AFDC) program. Connections between receipt of TANF and SSI are widely discussed in both disability policy and poverty research literatures because many families receiving TANF report disabilities. For both states and the individuals involved, it is generally financially advantageous for adults and children with disabilities to transfer from TANF to SSI. States gain because the federal government pays for the SSI benefit, and states can then use the TANF savings for other purposes. The families gain because the SSI benefits they acquire are greater than the TANF benefits they lose. The payoff to states from transferring welfare recipients to SSI was substantially increased when Congress replaced AFDC with TANF in 1996. States retained less than half of any savings achieved through such transfers under AFDC, but they retain all of the savings under TANF. Also, the work participation requirements under TANF have obligated states to address the work support needs of adults with disabilities who remain in TANF, and states can avoid these costs if adults have disabilities that satisfy SSI eligibility requirements. The incentive for TANF recipients to apply for SSI has increased over time as inflation has caused real TANF benefits to fall relative to payments received by SSI recipients. Trends in the financial incentives for transfer to SSI have not been studied in detail, and reliable general data on the extent of the interaction between TANF and SSI are scarce. In addition, some estimates of the prevalence of TANF receipt among SSI awardees are flawed because they fail to include adults receiving benefits in TANF-related Separate State Programs (SSPs). SSPs are assistance programs that are administered by TANF agencies but are paid for wholly from state funds. When the programs are conducted in a manner consistent with federal regulations, the money states spend on SSPs counts toward federal maintenance-of-effort (MOE) requirements, under which states must sustain a certain level of contribution to the costs of TANF and approved related activities. SSPs are used for a variety of purposes, including support of families who are in the process of applying for SSI. Until very recently, families receiving cash benefits through SSPs were not subject to TANF's work participation requirements. This article contributes to analysis of the interaction between TANF and SSI by evaluating the financial consequences of TANF-to-SSI transfer and developing new estimates of both the prevalence of receipt of SSI benefits among families receiving cash assistance from TANF and the proportion of new SSI awards that go to adults and children residing in families receiving TANF or TANF-related benefits in SSPs. Using data from the Urban Institute's Welfare Rules Database, we find that by 2003 an SSI award for a child in a three-person family dependent on TANF increased family income by 103.5 percent on average across states; an award to the adult in such a family increased income by 115.4 percent. The gain from both child and adult transfers increased by about 6 percent between 1996 (the eve of the welfare reform that produced TANF) and 2003. Using data from the Department of Health and Human Services' TANF/SSP Recipient Family Characteristics Survey, we estimate that 16 percent of families receiving TANF/SSP support in federal fiscal year 2003 included an adult or child SSI recipient. This proportion has increased slightly since fiscal year 2000. The Social Security Administration's current procedures for tabulating characteristics of new SSI awardees do not recognize SSP receipt as TANF We use differences in reported TANF-to-SSI flows between states with and without Separate State Programs to estimate the understatement of the prevalence of TANF-related SSI awards in states with SSPs. The results indicate that the absolute number of awards to AFDC (and subsequently) TANF/SSP recipients has declined by 42 percent for children and 25 percent for adults since the early 1990s. This result is a product of the decline in welfare caseloads. However, the monthly incidence of such awards has gone up-from less than 1 per 1,000 child recipients in calendar years 1991-1993 to 1.3 per 1,000 in 2001-2003 and, for adult recipients, from 1.6 per 1,000 in 1991-1993 to 4 per 1,000 in 2001-2003. From these results we conclude that a significant proportion of each year's SSI awards to disabled nonelderly people go to TANF/SSP recipients, and many families that receive TANF/SSP support include adults, children, or both who receive SSI. Given the Social Security Administration's efforts to improve eligibility assessment for applicants, to ensure timely access to SSI benefits for those who qualify, and to improve prospects for eventual employment of the disabled, there is definitely a basis for working with TANF authorities both nationally and locally on service coordination and on smoothing the process of SSI eligibility assessment. The Deficit Reduction Act of 2005 reauthorized TANF through fiscal year 2010, but with some rules changes that are important in light of the analysis presented in this article. The new law substantially increases effective federal requirements for work participation by adult TANF recipients and mandates that adults in Separate State Programs be included in participation requirements beginning in fiscal year 2007. Thus SSPs will no longer provide a means for exempting from work requirements families that are in the process of applying for SSI, and the increased emphasis on work participation could result in more SSI applications from adult TANF recipients.

Russia in the Arctic

DTIC Science & Technology

2011-07-01

strategy with emphasis on geostrate- gic analysis. The mission of SSI is to use independent analysis to conduct strategic studies that develop policy...De- fense, and the larger national security community. In addition to its studies , SSI publishes special reports on topics of special or immediate... on the SSI website. The SSI website address is: www.StrategicStudiesInstitute.army.mil. ***** The Strategic Studies Institute publishes a monthly e

Oleic acid levels regulated by glycerolipid metabolism modulate defense gene expression in Arabidopsis

PubMed Central

Kachroo, Aardra; Venugopal, Srivathsa C.; Lapchyk, Ludmila; Falcone, Deane; Hildebrand, David; Kachroo, Pradeep

2004-01-01

Stearoyl-acyl-carrier-protein-desaturase-mediated conversion of stearic acid (18:0) to oleic acid (18:1) is a key step, which regulates levels of unsaturated fatty acids in cells. We previously showed that stearoyl-acyl-carrier-protein-desaturase mutants ssi2/fab2 carrying a loss-of-function mutation in the plastidial glycerol-3-phosphate (G3P) acyltransferase (act1) have elevated 18:1 levels and are restored in their altered defense signaling. Because G3P is required for the acylation of 18:1 by G3P acyltransferase, it was predicted that reduction of G3P levels should increase 18:1 levels and thereby revert ssi2-triggered phenotypes. Here we show that a mutation in G3P dehydrogenase restores both salicylic acid- and jasmonic acid-mediated phenotypes of ssi2 plants. The G3P dehydrogenase gene was identified by map-based cloning of the ssi2 suppressor mutant rdc8 (gly1-3) and confirmed by epistatic analysis of ssi2 with gly1-1. Restoration of ssi2-triggered phenotypes by the gly1-3 mutation was age-dependent and correlated with the levels of 18:1. Regeneration of G3P pools by glycerol application in ssi2 and ssi2 gly1-3 plants caused a marked reduction in the 18:1 levels, which rendered these plants hypersensitive to glycerol. This hypersensitivity in ssi2 was rescued by the act1 mutation. Furthermore, overexpression of the ACT1 gene resulted in enhanced sensitivity to glycerol. Glycerol application also lowered the 18:1 content in SSI2 plants and converted these into ssi2-mimics. Our results show that 18:1 levels in plastids are regulated by means of acylation with G3P, and a balance between G3P and 18:1 is critical for the regulation of salicylic acid- and jasmonic acid-mediated signaling pathways. PMID:15044700

Risk factors for unavoidable removal of instrumentation after surgical site infection of spine surgery

PubMed Central

Tominaga, Hiroyuki; Setoguchi, Takao; Kawamura, Hideki; Kawamura, Ichiro; Nagano, Satoshi; Abematsu, Masahiko; Tanabe, Fumito; Ishidou, Yasuhiro; Yamamoto, Takuya; Komiya, Setsuro

2016-01-01

Abstract Surgical site infection (SSI) after spine instrumentation is difficult to treat, and often requires removal of instrumentation. The removal of instrumentation after spine surgery is a severe complication that can lead to the deterioration of activities of daily living and poor prognosis. Although there are many reports on SSI after spine surgery, few reports have investigated the risk factors for the removal of instrumentation after spine surgery SSI. This study aimed to identify the risk factors for unavoidable removal of instrumentation after SSI of spine surgery. We retrospectively reviewed 511 patients who underwent spine surgery with instrumentation at Kagoshima University Hospital from January 2006 to December 2014. Risk factors associated with SSI were analyzed via multiple logistic regression analysis. Parameters of the group that needed instrumentation removal were compared with the group that did not require instrumentation removal using the Mann–Whitney U and Fisher's exact tests. The posterior approach was used in most cases (453 of 511 cases, 88.6%). SSI occurred in 16 of 511 cases (3.14%) of spine surgery with instrumentation. Multivariate logistic regression analysis identified 2 significant risk factors for SSI: operation time, and American Society of Anesthesiologists physical status classification ≥ 3. Twelve of the 16 patients with SSI (75%) were able to keep the instrumentation after SSI. Pseudarthrosis occurred in 2 of 4 cases (50%) after instrumentation removal. Risk factors identified for instrumentation removal after spine SSI were a greater number of past surgeries, low preoperative hemoglobin, high preoperative creatinine, high postoperative infection treatment score for the spine, and the presence of methicillin-resistant Staphylococcus aureus. In these high risk cases, attempts should be made to decrease the risk factors preoperatively, and careful postoperative monitoring should be conducted. PMID:27787365

Risk factors for unavoidable removal of instrumentation after surgical site infection of spine surgery: A retrospective case-control study.

PubMed

Tominaga, Hiroyuki; Setoguchi, Takao; Kawamura, Hideki; Kawamura, Ichiro; Nagano, Satoshi; Abematsu, Masahiko; Tanabe, Fumito; Ishidou, Yasuhiro; Yamamoto, Takuya; Komiya, Setsuro

2016-10-01

Surgical site infection (SSI) after spine instrumentation is difficult to treat, and often requires removal of instrumentation. The removal of instrumentation after spine surgery is a severe complication that can lead to the deterioration of activities of daily living and poor prognosis. Although there are many reports on SSI after spine surgery, few reports have investigated the risk factors for the removal of instrumentation after spine surgery SSI. This study aimed to identify the risk factors for unavoidable removal of instrumentation after SSI of spine surgery. We retrospectively reviewed 511 patients who underwent spine surgery with instrumentation at Kagoshima University Hospital from January 2006 to December 2014. Risk factors associated with SSI were analyzed via multiple logistic regression analysis. Parameters of the group that needed instrumentation removal were compared with the group that did not require instrumentation removal using the Mann-Whitney U and Fisher's exact tests. The posterior approach was used in most cases (453 of 511 cases, 88.6%). SSI occurred in 16 of 511 cases (3.14%) of spine surgery with instrumentation. Multivariate logistic regression analysis identified 2 significant risk factors for SSI: operation time, and American Society of Anesthesiologists physical status classification ≥ 3. Twelve of the 16 patients with SSI (75%) were able to keep the instrumentation after SSI. Pseudarthrosis occurred in 2 of 4 cases (50%) after instrumentation removal. Risk factors identified for instrumentation removal after spine SSI were a greater number of past surgeries, low preoperative hemoglobin, high preoperative creatinine, high postoperative infection treatment score for the spine, and the presence of methicillin-resistant Staphylococcus aureus. In these high risk cases, attempts should be made to decrease the risk factors preoperatively, and careful postoperative monitoring should be conducted.

20 CFR 416.1100 - Income and SSI eligibility.

Code of Federal Regulations, 2011 CFR

2011-04-01

..., BLIND, AND DISABLED Income General § 416.1100 Income and SSI eligibility. You are eligible for supplemental security income (SSI) benefits if you are an aged, blind, or disabled person who meets the...

Impact of a surgical site infection (SSI) surveillance program in orthopedics and traumatology.

PubMed

Mabit, C; Marcheix, P S; Mounier, M; Dijoux, P; Pestourie, N; Bonnevialle, P; Bonnomet, F

2012-10-01

Surveillance of surgical site infections (SSI) is a priority. One of the fundamental principles for the surveillance of SSI is based on receiving effective field feedback (retro-information). The aim of this study was to report the results of a program of SSI surveillance and validate the hypothesis that there is a correlation between creating a SSI surveillance program and a reduction in SSI. The protocol was based on the weekly collection of surveillance data obtained directly from the different information systems in different departments. A delay of 3 months was established before extraction and analysis of data and information from the surgical teams. The NNIS index (National Nosocomial Infections Surveillance System) developed by the American surveillance system and the reduction of length of hospital stay index Journées d'hospitalisation évitées (JHE). Since the end of 2009, 7156 surgical procedures were evaluated (rate of inclusion 97.3%), and 84 SSI were registered with a significant decrease over time from 1.86% to 0.66%. A total of 418 days of hospitalization have been saved since the beginning of the surveillance system. Our surveillance system has three strong points: follow-up is continuous, specifically adapted to orthopedic traumatology and nearly exhaustive. The extraction of data directly from hospital information systems effectively improves the collection of data on surgical procedures. The implementation of a SSI surveillance protocol reduces SSI. Level III. Prospective study. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

Surgical site infections in an abdominal surgical ward at Kosovo Teaching Hospital.

PubMed

Raka, Lul; Krasniqi, Avdyl; Hoxha, Faton; Musa, Ruustem; Mulliqi, Gjyle; Krasniqi, Selvete; Kurti, Arsim; Dervishaj, Antigona; Nuhiu, Beqir; Kelmendi, Baton; Limani, Dalip; Tolaj, Ilir

2007-12-01

Abdominal surgical site infections (SSI) cause substantial morbidity and mortality for patients undergoing operative procedures. We determined the incidence of and risk factors for SSI after abdominal surgery in the Department of Abdominal Surgery at the University Clinical Centre of Kosovo (UCCK). Prospective surveillance of patients undergoing abdominal surgery was performed between December 2005 and June 2006. CDC definitions were followed to detect SSI and study forms were based on Europe Link for Infection Control through Surveillance (HELICS) protocol. A total of 253 surgical interventions in 225 patients were evaluated. The median age of patients was 42 years and 55.1% of them were male. The overall incidence rate of SSI was 12%. Follow-up was achieved for 84.1% of the procedures. For patients with an SSI, the median duration of hospitalization was 9 days compared with 4 days for those without an SSI (p2, use of antibiotic prophylaxis and NNIS class of >2 were all significant at p < .001. The SSI rates for the NNIS System risk classes 0, 1 and 2-3 were 4.2%, 46.7% and 100%, respectively. SSI caused considerable morbidity among surgical patients in UCCK. Appropriate active surveillance and infection control measures should be introduced during preoperative, intra-operative, and postoperative care to reduce infection rates.

Rates of Surgical Site Infection in Cholecystectomy: Comparison between a University Teaching Hospital, Madrid Region, Spain, and USA Rates.

PubMed

Rodríguez-Caravaca, Gil; Gil-Yonte, Pablo; Del-Moral-Luque, Juan Antonio; Lucas, Warren Covelé; Fernández-Cebrián, José María; Durán-Poveda, Manuel

2017-01-01

There are many factors that can influence surgical site infections (SSI) in cholecystectomies. Incidence of cholecystectomy SSI was studied and compared with the incidence in Madrid Region, Spain, and the United States. A prospective cohort study was conducted which included all patients who underwent gallbladder surgery for 5 consecutive years, at the Alcorcón Foundation University Teaching Hospital. SSI incidence rate was calculated. An association between risk factors and SSI incidence was assessed with the relative risk (RR). Infection rates were compared to those in the Madrid Region and to the overall Spanish and United States rates using the standardized infection ratio (SIR). The study included 1532 patients. Cumulative overall SSI was 1.96% (95% confidence interval [CI]: 1.3-2.7). The SIR was 0.89 with respect to the Madrid Region, 0.77 with respect to Spain's rate, and 1.77 with respect to the United States' rate. A laparoscopic route protected against infection (RR = 0.43; 95% CI: 0.2-0.9). Razor shaving in surgical preparation, duration of surgery, and neoplasm increased SSI incidence. SSI incidence rates among cholecystectomized patients at our hospital are higher than rates in the United States. A laparoscopic route protected against SSI. Copyright: © 2017 SecretarÍa de Salud

Postoperative Neurosurgical Infection Rates After Shared-Resource Intraoperative Magnetic Resonance Imaging: A Single-Center Experience with 195 Cases.

PubMed

Dinevski, Nikolaj; Sarnthein, Johannes; Vasella, Flavio; Fierstra, Jorn; Pangalu, Athina; Holzmann, David; Regli, Luca; Bozinov, Oliver

2017-07-01

To determine the rate of surgical-site infections (SSI) in neurosurgical procedures involving a shared-resource intraoperative magnetic resonance imaging (ioMRI) scanner at a single institution derived from a prospective clinical quality management database. All consecutive neurosurgical procedures that were performed with a high-field, 2-room ioMRI between April 2013 and June 2016 were included (N = 195; 109 craniotomies and 86 endoscopic transsphenoidal procedures). The incidence of SSIs within 3 months after surgery was assessed for both operative groups (craniotomies vs. transsphenoidal approach). Of the 109 craniotomies, 6 patients developed an SSI (5.5%, 95% confidence interval [CI] 1.2-9.8%), including 1 superficial SSI, 2 cases of bone flap osteitis, 1 intracranial abscess, and 2 cases of meningitis/ventriculitis. Wound revision surgery due to infection was necessary in 4 patients (4%). Of the 86 transsphenoidal skull base surgeries, 6 patients (7.0%, 95% CI 1.5-12.4%) developed an infection, including 2 non-central nervous system intranasal SSIs (3%) and 4 cases of meningitis (5%). Logistic regression analysis revealed that the likelihood of infection significantly decreased with the number of operations in the new operational setting (odds ratio 0.982, 95% CI 0.969-0.995, P = 0.008). The use of a shared-resource ioMRI in neurosurgery did not demonstrate increased rates of infection compared with the current available literature. The likelihood of infection decreased with the accumulating number of operations, underlining the importance of surgical staff training after the introduction of a shared-resource ioMRI. Copyright © 2017 Elsevier Inc. All rights reserved.

Association Between Smoking Status, Preoperative Exhaled Carbon Monoxide Levels, and Postoperative Surgical Site Infection in Patients Undergoing Elective Surgery

PubMed Central

Martin, David P.; Thompson, Rodney; Schroeder, Darrell R.; Hanson, Andrew C.; Warner, David O.

2017-01-01

Importance Cigarette smoking is a risk factor for many perioperative complications, including surgical site infection (SSI). The duration of abstinence from smoking required to reduce this risk is unknown. Objectives To evaluate if abstinence from smoking on the day of surgery is associated with a decreased frequency of SSI in patients who smoke cigarettes and to confirm that smoking is significantly independently associated with SSI when adjustment is made for potentially relevant covariates, such as body mass index. Design, Setting, and Participants In this observational, nested, matched case-control study, 2 analyses were performed at an academic referral center in the upper Midwest. Cases included all patients undergoing elective surgical procedures at Mayo Clinic, Rochester, Minnesota, between January 1, 2009, and July 31, 2014 (inclusive) who subsequently developed an SSI. Controls for both analyses were matched on age, sex, and type of surgery. Exposures Smoking status and preoperative exhaled carbon monoxide level, assessed by nurses in the preoperative holding area. Patients were classified as smoking on the day of surgery if they self-reported smoking or if their preoperative exhaled carbon monoxide level was 10 ppm or higher. Main Outcomes and Measures Surgical site infection after a surgical procedure at Mayo Clinic, Rochester, as identified by routine clinical surveillance using National Healthcare Safety Network criteria. Results Of the 6919 patients in the first analysis, 3282 (47%) were men and 3637 (53%) were women; median age (interquartile range) for control and SSI cases was 60 (48-70). Of the 392 patients in the second analysis, 182 (46%) were men and 210 (54%) were women; median age (interquartile range) for controls was 53 (45-49) and for SSI cases was 51 (45-60). During the study period, approximately 2% of surgical patients developed SSI annually. Available for the first analysis (evaluating the influence of current smoking status) were 2452 SSI cases matched to 4467 controls. The odds ratio for smoking and SSI was 1.51 (95% CI, 1.20-1.90; P < .001), which remained statistically significant after adjusting for covariates. In the second analysis (evaluating the influence of smoking on the day of surgery), there were 137 SSI cases matched to 255 controls. The odds ratio for smoking on the day of surgery and SSI was 1.96 (95% CI, 1.23-3.13; P < .001), which remained statistically significant after adjusting for covariates. Preoperative exhaled carbon monoxide level was not associated with the frequency of SSI, suggesting that the association between smoking on the day of surgery and SSI was not related to preoperative exhaled carbon monoxide levels. Conclusions and Relevance Current smoking is associated with the development of SSI, and smoking on the day of surgery is independently associated with the development of SSI. These data cannot distinguish whether abstinence per se reduces risk or whether it is associated with other factors that may be causative. PMID:28199450

Performance of Shear Wave Elastography for Differentiation of Benign and Malignant Solid Breast Masses

PubMed Central

Song, Yi-Jiang; Deng, Zhu-Jun; Gao, Jian; Xie, Yan; Yin, Tian-Sheng; Ying, Li; Tang, Kai-Fu

2013-01-01

Objectives To perform a meta-analysis assessing the ability of shear wave elastography (SWE) to identify malignant breast masses. Methods PubMed, the Cochrane Library, and the ISI Web of Knowledge were searched for studies evaluating the accuracy of SWE for identifying malignant breast masses. The diagnostic accuracy of SWE was evaluated according to sensitivity, specificity, and hierarchical summary receiver operating characteristic (HSROC) curves. An analysis was also performed according to the SWE mode used: supersonic shear imaging (SSI) and the acoustic radiation force impulse (ARFI) technique. The clinical utility of SWE for identifying malignant breast masses was evaluated using analysis of Fagan plot. Results A total of 9 studies, including 1888 women and 2000 breast masses, were analyzed. Summary sensitivities and specificities were 0.91 (95% confidence interval [CI], 0.88–0.94) and 0.82 (95% CI, 0.75–0.87) by SSI and 0.89 (95% CI, 0.81–0.94) and 0.91 (95% CI, 0.84–0.95) by ARFI, respectively. The HSROCs for SSI and ARFI were 0.92 (95% CI, 0.90–0.94) and 0.96 (95% CI, 0.93–0.97), respectively. SSI and ARFI were both very informative, with probabilities of 83% and 91%, respectively, for correctly differentiating between benign and malignant breast masses following a “positive” measurement (over the threshold value) and probabilities of disease as low as 10% and 11%, respectively, following a “negative” measurement (below the threshold value) when the pre-test probability was 50%. Conclusions SWE could be used as a good identification tool for the classification of breast masses. PMID:24204613

Spring Indices (SI): National (and Global) Indicators of Climate Impacts on Ecosystems and Society

NASA Astrophysics Data System (ADS)

Betancourt, J. L.; Schwartz, M. D.; Ault, T. R.; McCabe, G. J.; Macalady, A. K.; Pederson, G. T.; Cook, B. P.; Henebry, G. M.; Moore, D. J.; Enquist, C.

2011-12-01

Indicators are vital in everyday life, such as tracking blood pressure to assess your health or monitoring the nation's economy using unemployment rates. Tracking the state of the environment in a uniform and integrated manner requires simple and broadly-applicable indicators of year-to-year variability and change. For example, indices such as the Start of Season (SOS) in remotely-sensed land surface phenology, Center of Mass (CM) in the hydrology of snowfed inland waters, and other biogeophysical metrics are being widely used as metrics of global change in seasonal timing. Here, we present a new, standardized spring index (SSI) that uses only daily minimum and maximum temperatures as input. This builds on an earlier version of the spring indices (SI) for lilac and honeysuckle phenology (first leaf and first flower) that required plant chilling to be satisfied over winter. The SSI tracks the transition from winter to spring by tallying phenologically relevant variables, (such as the number and intensity of warm days and total hours of sunlight) from January 1st onward, while ignoring the chilling requirement. This adjustment allows determination of first leaf and first bloom dates across the entire USA, including southernmost latitudes. Outputs from the new SSI is highly correlated with the earlier version, and both models process weather data into indices directly related to growth and development of many plants. Spatially averaged anomalies of SSI are well correlated with remotely sensed data and phenological observations from a wide variety of trees and shrubs in Europe, China, and North America. An advantage of SSI is that it only "sees" the atmosphere, meaning that it is free of local biological effects. Therefore, it can enhance the ability to identify important relationships between the large-scale climate modes of variability and the index itself, an advantage over other plant-based indices (such as SOS). If the state of these atmospheric modes can be anticipated with enough lead time, the dates of spring onset might be predictable, and thus could be used to manage natural resources, optimize food production, and mitigate natural hazards such as wildfires. SSI shows sufficient promise to be considered a national indicator for the environmental consequences of climatic variability and change.

Surgical site infections in an abdominal surgical ward at Kosovo Teaching Hospital.

PubMed

Raka, Lul; Krasniqi, Avdyl; Hoxha, Faton; Musa, Ruustem; Mulliqi, Gjyle; Krasniqi, Selvete; Kurti, Arsim; Dervishaj, Antigona; Nuhiu, Beqir; Kelmendi, Baton; Limani, Dalip; Tolaj, Ilir

2008-01-01

Abdominal surgical site infections (SSI) cause substantial morbidity and mortality for patients undergoing operative procedures. We determined the incidence of and risk factors for SSI after abdominal surgery in the Department of Abdominal Surgery at the University Clinical Centre of Kosovo (UCCK). Prospective surveillance of patients undergoing abdominal surgery was performed between December 2005 and June 2006. CDC definitions were followed to detect SSI and study forms were based on Europe Link for Infection Control through Surveillance (HELICS) protocol. A total of 253 surgical interventions in 225 patients were evaluated. The median age of patients was 42 years and 55.1% of them were male. The overall incidence rate of SSI was 12%. Follow-up was achieved for 84.1% of the procedures. For patients with an SSI, the median duration of hospitalization was 9 days compared with 4 days for those without an SSI (p < 0.001). Surgical procedures were classified as emergent in 53.3% of cases. Superficial incisional SSI was most common (55%). Clinical infections were culture positive in 40.7% of cases. Duration of operation, duration of preoperative stay, wound class, ASA score > 2, use of antibiotic prophylaxis and NNIS class of > 2 were all significant at p < .001. The SSI rates for the NNIS System risk classes 0, 1 and 2-3 were 4.2%, 46.7% and 100%, respectively. SSI caused considerable morbidity among surgical patients in UCCK. Appropriate active surveillance and infection control measures should be introduced during preoperative, intra-operative, and postoperative care to reduce infection rates.

Surveillance, Auditing, and Feedback Can Reduce Surgical Site Infection Dramatically: Toward Zero Surgical Site Infection.

PubMed

Manivannan, Bhavani; Gowda, Deepak; Bulagonda, Pradeep; Rao, Abhishek; Raman, Sai Suguna; Natarajan, Shanmuga Vadivoo

2018-04-01

We evaluated the Surveillance of Surgical Site Infection (SSI), Auditing, and Feedback (SAF) effect on the rate of compliance with an SSI care bundle and measured its effectiveness in reducing the SSI rate. A prospective cohort study from January 2014 to December 2016 was classified into three phases: pre-SAF, early-SAF, and late-SAF. Pre-operative baseline characteristics of 24,677 patients who underwent orthopedic, cardiovascular thoracic surgery (CTVS) or urologic operations were recorded. Univariable analyses of the SSI rates in the pre-SAF and post-SAF phases were performed. Percentage compliance and non-compliance with each care component were calculated. Correlation between reduction in the SSI rate and increase in compliance with the pre-operative, peri-operative, and post-operative care-bundle components was performed using the Spearman test. There was a significant decrease in the SSI rate in orthopedic procedures that involved surgical implantation and in mitral valve/aortic valve (MVR/AVR) cardiac operations, with a relative risk (RR) ratio of 0.19 (95% confidence interval [CI] 0.12-0.31) and 0.08 (95% CI 0.03-0.22), respectively. The SSI rate was inversely correlated with the rate of compliance with pre-operative (r = -0.738; p = 0.037), peri-operative (r = - 0.802; p = 0.017), and post-operative (r = -0.762; p = 0.028) care bundles. Implementation of the Surveillance of SSI, Auditing, and Feedback bundle had a profound beneficial effect on the SSI rate, thereby reducing healthcare costs and improving patient quality of life.

First-in-human safety and immunogenicity investigations of three adjuvanted reduced dose inactivated poliovirus vaccines (IPV-Al SSI) compared to full dose IPV Vaccine SSI when given as a booster vaccination to adolescents with a history of IPV vaccination at 3, 5, 12months and 5years of age.

PubMed

Lindgren, Line M; Tingskov, Pernille N; Justesen, Annette H; Nedergaard, Bettina S; Olsen, Klaus J; Andreasen, Lars V; Kromann, Ingrid; Sørensen, Charlotte; Dietrich, Jes; Thierry-Carstensen, Birgit

2017-01-23

There is a demand of affordable IPV in the World. Statens Serum Institut (SSI) has developed three reduced dose IPV formulations adsorbed to aluminium hydroxide; 1/3 IPV-Al, 1/5 IPV-Al and 1/10 IPV-Al SSI, and now report the results of the first investigations in humans. 240 Danish adolescents, aged 10-15years, and childhood vaccinated with IPV were booster vaccinated with 1/3 IPV-Al, 1/5 IPV-Al, 1/10 IPV-Al or IPV Vaccine SSI. The booster effects (GMTRs) of the three IPV-Al SSI were compared to IPV Vaccine SSI, and evaluated for non-inferiority. The pre-vaccination GMTs were similar across the groups; 926 (type 1), 969 (type 2) and 846 (type 3) in the total trial population. The GMTRs by poliovirus type and IPV formulation were: Type 1: 17.0 (1/3 IPV-Al), 13.0 (1/5 IPV-Al), 7.1 (1/10 IPV-Al) and 42.2 (IPV Vaccine SSI). Type 2: 12.5 (1/3 IPV-Al), 13.1 (1/5 IPV-Al), 7.6 (1/10 IPV-Al) and 47.8 (IPV Vaccine SSI). Type 3: 14.5 (1/3 IPV-Al), 16.2 (1/5 IPV-Al), 8.9 (1/10 IPV-Al) and 62.4 (IPV Vaccine SSI) Thus, the three IPV-Al formulations were highly immunogenic, but inferior to IPV Vaccine SSI, in this booster vaccination trial. No SAE and no AE of severe intensity occurred. 59.2% of the subjects reported at least one AE. Injection site pain was the most frequent AE in all groups; from 24.6% to 43.3%. Injection site redness and swelling frequencies were<5% in most and<10% in all groups. The most frequent systemic AEs were fatigue (from 8.2% to 15.0%) and headache (from 15.0% to 28.3%). Most AEs were of mild intensity. In conclusion, the three IPV-Al SSI were safe in adolescents and the booster effects were satisfactory. ClinicalTrials.gov registration number: NCT02280447. Copyright © 2016. Published by Elsevier Ltd.

Reforming Science and Mathematics Education

NASA Astrophysics Data System (ADS)

Lagowski, J. J.

1995-09-01

Since 1991, the National Science Foundation has signed cooperative agreements with 26 states to undertake ambitious and comprehensive initiatives to reform science, mathematics, and technology education. Collectively, those agreements are known as the State Systemic Initiatives (SSI's). Two complimentary programs, The Urban and Rural Systemic Initiatives (USI's and RSI's), address similar reforms in the nation's largest cities and poorest rural areas. The SSI Program departs significantly from past NSF practice in several ways. The funding is for a longer term and is larger in amount, and the NSF is taking a more activist role, seeking to leverage state and private funds and promote the coordination of programs within states. The Initiatives also have a stronger policy orientation than previous NSF programs have had. The NSF strategy is a reflection of the growing and widely held view that meaningful reforms in schools are most likely to be achieved through state initiatives that set clear and ambitious learning goals and standards; align all of the available policy levers in support of reform; stimulate school-level initiatives; and mobilize human and financial resources to support these changes. Two premises underlie systemic reform: (1) all children can meet significantly higher standards if they are asked to do so and given adequate opportunities to master the content, and (2) state and local policy changes can create opportunities by giving schools strong and consistent signals about the changes in practice and performance that are expected. Because this is an enormous investment of Federal resources that is intended to bring about deep, systemic improvement in the nation's ability to teach science and mathematics effectively, the NSF has contracted with a consortium of independent evaluators to conduct a review of the program. The first of the SSI's were funded in 1991, sufficiently long ago to begin to formulate some initial impressions of their impact. Take, for example, the various SSI's statements of "good educational practice." Most SSI's began their initiatives by establishing clear goals for what students should know and be able to do, reflecting the emergence of a national consensus for broad standards for just about every aspect of the educational process. The concerned persons in each SSI--policy-makers, educators, mathematicians, and scientists--have not necessarily reached the same conclusions about what children should learn or even what efforts are needed to put the necessary changes in place, but they are focused on common goals as expressed locally. The recent national dialogues about goals and standards have provided the basis for a remarkably consistent image of what states--at least the SSI states--consider good educational practice. The differences that do occur across states reflect variations in demographics, geography, resources, values, and educational structure. All the states with SSI's, regardless of their primary strategy, have address the professional development of teachers. Collectively, the SSI's reported that professional development services were provided to more than 50,000 teachers during the past year, which is approximately eight percent of the public school teachers in the participating states. The number of teachers participating varied by grade level and subject matter. Some states, for example, reported reaching more than one in every five middle-school mathematics teachers, but only one in every 20 high-school mathematics teachers. Focusing SSI resources on the professional development of classroom teachers implies changing their skill levels, knowledge, and beliefs. Attitudes and perceptions of administrators also changed in the process. The challenge lies in developing a strategy that provides on-going, in-depth professional development that reaches a significant portion of those who teach mathematics and the sciences. Not only must an effective development model(s), be provided, the infrastructure to accommodate all teachers must be created as well. Most states' strategies include building statewide capacity for professional development beyond the opportunities sponsored directly by the SSI's. Three factors are explicitly recognized: (1) the SSI's do not have the resources to reach all teachers in most states, (2) the SSI's funding will eventually run out, and (3) the need for professional development will be on-going. Some states have developed regional centers to serve the on-going professional development needs of teachers. Another capacity-building strategy involves the use of technology to support teachers' efforts to change their practices. New non-governmental organizations are also playing key leadership roles in a number of states. Such organizations are of particular interest because they have the potential to build broad-based, bipartisan support that can sustain the SSI vision and its activities across electoral cycles. One of the central tenets of systematic reform is the alignment of the myriad of public policies governing the educational enterprise, from teacher credentiality to student assessment to textbook adoption, with the new goals and standards. In localities where the revision of state policies is simply not considered a fruitful strategy, strong traditions of local control are to be found. Some SSI's are working to improve the preparation of teachers. A common strategy has been to issue a request for proposals (RFP) to institutions for higher education to design and implement innovative pre-service teacher education programs. Scientists and mathematicians can have an enormous impact on this aspect of the SSI's mission, by becoming intimately involved in the development of courses that are meaningful for would-be teachers. This is the area where scientists and mathematicians can leverage their technical knowledge and skills to help educate teachers. Creating and sustaining a coalition of groups powerful enough to launch fundamental reforms in public education is challenging. The coalition must be able to reach consensus on a vision of reform and, then, sustain the reform over an extended period of time. This is not easy when power and authority are highly fragmented (and perhaps at odds), where interest groups live or die on confromtation politics, when public and private sectors exhibit a basic distrust of one another, and when everyone is an expert--real or imagined--on topics more-or-less related to education. In addition, the SSI's are operating in a turbulent climate. Policy makers may be working on standards-based reforms in K-12 education at the same time they are seeking efficiencies in state government, consider deregulation, and experiment with integrated social services. Criminal justice, health, and welfare are competing in state capitols for the resources required to bring about education reforms. And, within this shifting policy landscape, the SSI's are seeking higher priority for mathematics and science, as well as attempting to develop the infrastructure and capacity to support change in the schools. Simply keeping mathematics and science education high on the agenda of state policy-makers is a challenge. Each of these component strategies of the SSI's is important. The critical question is whether, in a given state, the SSI strategies, when combined with other state reform initiatives, form a coherent, comprehensive plan for improving public education. While the oldest of the SSI's are only in their fourth year of activity, it is already clear that the reforms they are seeking will take longer than five years to accomplish. (The SSI's are supported by five-year grants from the NSF.) The instructional reforms advocated by the SSI's require time to implement, and once in place, additional time to produce results. Elected officials often focus on the short-term, and they can become impatient when the results are slow. There appears to be no ready solution to the conflict between the long-run agendas of school reforms and the short-term needs of legislators. This is clearly a race for long-distance runners.

Martian Dust Aerosol Size and Shape as Constrained by Phoenix Lander Polarimetry

NASA Astrophysics Data System (ADS)

Lemmon, Mark T.; Mason, Emily L.

2014-11-01

Dust aerosol morphology is important to dust transport and the radiative heating of the Martian atmosphere. Previous analyses of Mars dust have shown that spherical particles are a bad analog for the dust, in terms of reproducing the distribution of scattered light. Parameterized scattering, based on laboratory observations of scattering by irregular dust particles, has been used for Viking, Pathfinder and Mars Exploration Rover data [Pollack et al., J. Geophys. Res. 100, 1995; Tomasko et al., J. Geophys. Res. 104, 1999; Lemmon et al., Science 306, 2004]. Analytical calculations have shown that cylinders are a better scattering analog than spheres [Wolff et al., J. Geophys. Res. 114, 2009]. Terrestrial studies have shown that a diverse assortment of triaxial ellipsoids is a good analog for dust aerosol [Bi et al., Applied Optics 48, 2009].The Phoenix Lander operated in the Martian arctic for 5 months of 2008, around the northern summer solstice. During the mission atmospheric optical depth was tracked through direct solar imaging by the Surface Stereo Imager (SSI). For solar longitude (Ls) 78-95 and 140-149, small dust storms dominated the weather. Low-dust conditions (optical depths <0.4) dominated during Ls 95-140, with sporadic ice clouds becoming more common after Ls 108. The SSI also obtained occasional cross-sky photometric data through several filters from 440 to 1000 nm and cross-sky polarimetry at 750 nm wavelength. Radiative transfer models of the sky radiance distribution are consistent with dust aerosols in the same 1.3-1.6 micron range reported for models of observations from previous missions. Cylinders, triaxial ellipsoids, and the parametric model can fit sky radiances; spheres cannot. The observed linear polarization, which reached 4-5% and had a similar angular distribution to Rayleigh polarization, is similar to the triaxial ellipsoid model, but not spheres or cylinders. An extension to the parametric model using 7-10% Rayleigh scattering mixed with unpolarized scattering is also an adequate model.

A Multi-Disciplinary Review of the Potential Association between Closed-Suction Drains and Surgical Site Infection

PubMed Central

Reiffel, Alyssa J.; Barie, Philip S.

2013-01-01

Abstract Background Despite the putative advantages conferred by closed-suction drains (CSDs), the widespread utilization of post-operative drains has been questioned due to concerns regarding both efficacy and safety, particularly with respect to the risk of surgical site infection (SSI). Although discipline-specific reports exist delineating risk factors associated with SSI as they relate to the presence of CSDs, there are no broad summary studies to examine this issue in depth. Methods The pertinent medical literature exploring the relationship between CSDs and SSI across multiple surgical disciplines was reviewed. Results Across most surgical disciplines, studies to evaluate the risk of SSI associated with routine post-operative CSD have yielded conflicting results. A few studies do suggest an increased risk of SSI associated with drain placement, but are usually associated with open drainage and not the use of CSDs. No studies whatsoever attribute a decrease in the incidence of SSI (including organ/space SSI) to drain placement. Conclusions Until additional, rigorous randomized trials are available to address the issue definitively, we recommend judicious use and prompt, timely removal of CSDs. Given that the evidence is scant and weak to suggest that CSD use is associated with increased risk of SSI, there is no justification for the prolongation of antibiotic prophylaxis to “cover” an indwelling drain. PMID:23718273

Prolonged Operative Duration Increases Risk of Surgical Site Infections: A Systematic Review

PubMed Central

Chen, Brian Po-Han; Soleas, Ireena M.; Ferko, Nicole C.; Cameron, Chris G.; Hinoul, Piet

2017-01-01

Abstract Background: The incidence of surgical site infection (SSI) across surgical procedures, specialties, and conditions is reported to vary from 0.1% to 50%. Operative duration is often cited as an independent and potentially modifiable risk factor for SSI. The objective of this systematic review was to provide an in-depth understanding of the relation between operating time and SSI. Patients and Methods: This review included 81 prospective and retrospective studies. Along with study design, likelihood of SSI, mean operative times, time thresholds, effect measures, confidence intervals, and p values were extracted. Three meta-analyses were conducted, whereby odds ratios were pooled by hourly operative time thresholds, increments of increasing operative time, and surgical specialty. Results: Pooled analyses demonstrated that the association between extended operative time and SSI typically remained statistically significant, with close to twice the likelihood of SSI observed across various time thresholds. The likelihood of SSI increased with increasing time increments; for example, a 13%, 17%, and 37% increased likelihood for every 15 min, 30 min, and 60 min of surgery, respectively. On average, across various procedures, the mean operative time was approximately 30 min longer in patients with SSIs compared with those patients without. Conclusions: Prolonged operative time can increase the risk of SSI. Given the importance of SSIs on patient outcomes and health care economics, hospitals should focus efforts to reduce operative time. PMID:28832271

A single-center retrospective review of postoperative infectious complications in the surgical management of mandibular fractures: Postoperative antibiotics add no benefit.

PubMed

Domingo, Fernando; Dale, Elizabeth; Gao, Cuilan; Groves, Cynthia; Stanley, Daniel; Maxwell, Robert A; Waldrop, Jimmy L

2016-12-01

Mandibular fractures are common facial injuries and treatment may be complicated by post-operative infection. Risk of infection from contamination with oral flora is well established but no consensus exists regarding antibiotic prophylaxis. The purpose of this study is to assess risk factors and perioperative antibiotics on surgical site infection (SSI) rates following mandibular fracture surgery. Retrospective medical record review was completed for trauma patients of any age surgically treated for mandibular fractures at a Level I Trauma Center from September 2006 to June 2012. Outcomes analysis was performed to determine SSI rates related to perioperative antibiotic use and other risk factors that may contribute to SSI. 359 patients met inclusion criteria for analysis. 76% were male. Mean age was 30.5 years. Thirty-eight patients developed SSI (10.6%). SSI rate was lower in closed versus open surgery (3.2% vs. 16.3%, p=0.0001), and in closed versus open fractures (1% vs. 14%, p=0.0005). SSI rate increased in patients with tobacco, alcohol, and drug use (14.6%, 13.2%, 53.6%, p<0.0001), traumatic dental injuries (19.6%, p=0.0110), and patients in motor vehicle crashes (12.2%, p=0.0062). SSI rates stratified by Injury Severity Score (ISS) less than or equal to 16 (23/255 [9%]) versus ISS greater than 16 (15/104 [14%]) trended toward more severely injured patients developing SSI, p=0.1347. SSI rate was similar in patients who did and did not receive post-operative antibiotics (14.7% vs. 9.6%, p=0.2556). Type of antibiotic, duration of post-operative antibiotic administration, and duration between injury and surgery did not effect SSI rate. Findings suggest that following surgical treatment of mandible fractures, open surgery, open fractures, and risk factors including substance abuse, traumatic dental injury, and mechanism of injury significantly increase SSI rates, while post-operative antibiotics do not appear to provide additional benefit compared to pre-operative antibiotics alone. Therapeutic study, level IV.

Science teachers teaching socioscientific issues (SSI): Four case studies

NASA Astrophysics Data System (ADS)

Lee, Hyunju

Socioscientific issues (SSI) are a class of issues that represent the social, ethical, and moral aspects of science in society. The need for the inclusion of SSI into science curricula has been generally accepted, but relatively few science teachers have incorporated SSI into their courses. Most science teachers feel that their most important task by far is to teach the principles of science, and any substantive pedagogical changes represent a burden. However, there are some teachers who address SSI out of personal initiatives. This dissertation study investigates four high school science teachers who address SSI out of their own initiative and explores their deeper inspirations, values, philosophies, and personal ideals that lead them to teach SSI. The overall approach is based on essentialist methodology (Witz, Goodwin, Hart, & Thomas, 2001; Witz, 2006a) with its focus on "the participant as ally" and "essentialist portraiture." The primary data source is four to six in-depth interviews with individual teachers (about 40-90 minutes for each interview). The interviews are complemented by extensive classroom observations of individual teachers' teaching SSI and by document analysis (including teaching materials, rubrics, student group projects and journals, etc.). There are two major findings. First, the teachers' deeper values and ideals are a source of larger inspiration that plays a significant role in changing their teaching practice. This inspiration may involve higher aspects (e.g., deep concern for students' development, unselfishness, caring, etc.) and commitment. Their teaching represents an integration of their personal experiences, values, concerns, and worldviews, which forms a larger inspiration for teaching. Teaching SSI is a part of this larger process. Second, the current curriculum reforms (STS, SSI, and NOS) only suggest theoretical ideals and do not effectively touch teachers' deeper values and ideals. Basically, the teachers are doing what they think is important for students and are developing their own approaches without any contact with the reform efforts. This brings some consequences in their teaching of SSI. Overall, this study suggests that real changes in science education can be achieved only if they are synchronized with individual teachers' deeper motivations.

Evaluating the use of antibiotic prophylaxis during open reduction and internal fixation surgery in patients at low risk of surgical site infection.

PubMed

Xu, Sheng-Gen; Mao, Zhao-Guang; Liu, Bin-Sheng; Zhu, Hui-Hua; Pan, Hui-Lin

2015-02-01

Widespread overuse and inappropriate use of antibiotics contribute to increasingly antibiotic-resistant pathogens and higher health care costs. It is not clear whether routine antibiotic prophylaxis can reduce the rate of surgical site infection (SSI) in low-risk patients undergoing orthopaedic surgery. We designed a simple scorecard to grade SSI risk factors and determined whether routine antibiotic prophylaxis affects SSI occurrence during open reduction and internal fixation (ORIF) orthopaedic surgeries in trauma patients at low risk of developing SSI. The SSI risk scorecard (possible total points ranged from 5 to 25) was designed to take into account a patient's general health status, the primary cause of fractures, surgical site tissue condition or wound class, types of devices implanted, and surgical duration. Patients with a low SSI risk score (≤8 points) who were undergoing clean ORIF surgery were divided into control (routine antibiotic treatment, cefuroxime) and evaluation (no antibiotic treatment) groups and followed up for 13-17 months after surgery. The infection rate was much higher in patients with high SSI risk scores (≥9 points) than in patients with low risk scores assigned to the control group (10.7% vs. 2.2%, P<0.0001). SSI occurred in 11 of 499 patients in the control group and in 13 of 534 patients in the evaluation group during the follow-up period of 13-17 months. The SSI occurrence rate did not differ significantly (2.2% vs. 2.4%, P=0.97) between the control and evaluation groups. Routine antibiotic prophylaxis does not significantly decrease the rate of SSI in ORIF surgical patients with a low risk score. Implementation of this scoring system could guide the rational use of perioperative antibiotics and ultimately reduce antibiotic resistance, health care costs, and adverse reactions to antibiotics. Copyright © 2014 Elsevier Ltd. All rights reserved.

High humidity suppresses ssi4-mediated cell death and disease resistance upstream of MAP kinase activation, H2O2 production and defense gene expression.

PubMed

Zhou, Fasong; Menke, Frank L H; Yoshioka, Keiko; Moder, Wolfgang; Shirano, Yumiko; Klessig, Daniel F

2004-09-01

The Arabidopsis ssi4 mutant, which exhibits spontaneous lesion formation, constitutive expression of pathogenesis-related (PR) genes and enhanced resistance to virulent bacterial and oomycete pathogens, contains a gain-of-function mutation in a TIR-NBS-LRR type R gene. Epistatic analyses revealed that both PR gene expression and disease resistance are activated via a salicylic acid (SA)- and EDS1-dependent, but NPR1- and NDR1-independent signaling pathway. In this study, we demonstrate that in moderate relative humidity (RH; 60%), the ssi4 mutant accumulates H(2)O(2) and SA prior to lesion formation and displays constitutive activation of the MAP kinases AtMPK6 and AtMPK3. It also constitutively expresses a variety of defense-associated genes, including those encoding the WRKY transcription factors AtWRKY29 and AtWRKY6, the MAP kinases AtMPK6 and AtMPK3, the powdery mildew R proteins RPW8.1 and RPW8.2, EDS1 and PR proteins. All of these ssi4-induced responses, as well as the chlorotic, stunted morphology and enhanced disease resistance phenotype, are suppressed by high RH (95%) growth conditions. Thus, a humidity sensitive factor (HSF) appears to function at an early point in the ssi4 signaling pathway. All ssi4 phenotypes, except for MAP kinase activation, also were suppressed by the eds1-1 mutation. Thus, ssi4-induced MAP kinase activation occurs downstream of the HSF but either upstream of EDS1 or on a separate branch of the ssi4 signaling pathway. SA is a critical signaling component in ssi4-mediated defense responses. However, exogenously supplied SA failed to restore lesion formation in high RH-grown ssi4 plants, although it induced defense gene expression. Thus, additional signals also are involved.

Percent body fat and prediction of surgical site infection.

PubMed

Waisbren, Emily; Rosen, Heather; Bader, Angela M; Lipsitz, Stuart R; Rogers, Selwyn O; Eriksson, Elof

2010-04-01

Obesity is a risk factor for surgical site infection (SSI) after elective surgery. Body mass index (BMI) is commonly used to define obesity (BMI >or=30 kg/m(2)), but percent body fat (%BF) (obesity is >25%BF [men]; >31%BF [women]) might better predict SSI risk because BMI might not reflect body composition. This prospective study included 591 elective surgical patients 18 to 64 years of age from September 2008 through February 2009. Height and weight were measured for BMI. %BF was calculated by bioelectrical impedance analysis. Preoperative, operative, and 30-day postoperative data were captured through interviews and chart review. Our primary, predetermined outcomes measurement was SSI as defined by the Center for Disease Control and Prevention. Mean %BF and BMI were 34+/-10 and 29+/-8, respectively. Four-hundred and nine (69%) patients were obese by %BF; 225 (38%) were obese by BMI. SSI developed in 71 (12%) patients. With BMI defining obesity, SSI incidence was 12.3% in nonobese and 11.6% in obese patients (p = 0.8); Using %BF, SSI occurred in 5.0% of nonobese and 15.2% of obese patients (p < 0.001). In univariate analyses, significant predictors of SSI were %BF (p = 0.005), obesity by %BF (p < 0.001), smoking (p = 0.002), National Nosocomial Infections Surveillance score (p < 0.001), postoperative hyperglycemia (p = 0.03), and anemia (p = 0.02). In multivariable analysis, obese patients by %BF had a 5-fold higher risk for SSI than nonobese patients (odds ratio = 5.3; 95% CI, 1.2-23.1; p = 0.03). Linear regression was used to show that there is a positive, nonlinear relationship between %BF and BMI. Obesity, defined by %BF, is associated with a 5-fold increased SSI risk. This risk increases as %BF increases. %BF is a more sensitive and precise measurement of SSI risk than BMI. Additional studies are required to better understand this relationship. Copyright (c) 2010 American College of Surgeons. Published by Elsevier Inc. All rights reserved.

Predictive factors for surgical site infection in general surgery.

PubMed

Haridas, Manjunath; Malangoni, Mark A

2008-10-01

Global parameters, such as wound class, the American Society of Anesthesiologists' physical classification score, and prolonged operative time, have been associated with the risk of surgical site infection (SSI). We hypothesized that additional risk factors for SSI would be identified by controlling for these parameters and that deep and organ/space SSI may have different risk factors for occurrence. A retrospective review was performed on general and vascular surgical patients who underwent an operation between June 2000 and June 2006 at a single institution. Patients with SSI were matched with a case-control cohort of patients without infection (no SSI) according to age, sex, ASA score, wound class, and type of operative procedure. Data were analyzed using bivariate and regression analyses. Overall, 10,253 general surgical procedures were performed during the 6-year period; 316 patients (3.1%) developed SSI. In all, 300 patients with 251 superficial (83.6%), 22 deep (7.3%), and 27 organ/space (9%) SSIs were matched for comparison. Multivariate logistic regression analysis identified previous operation (odds ratio [OR], 2.4; 95% confidence interval [CI] = 1.6-3.7), duration of operation >or=75th percentile (OR, 1.8; 95% CI = 1.2-2.8), hypoalbuminemia (OR, 1.8; 95% CI = 1.1-2.8), and a history of chronic obstructive pulmonary disease (OR, 1.7; 95% CI = 1.0-2.8) as independent risk factors for SSI. Only hypoalbuminemia (OR, 2.9; 95% CI = 1.4-6.3) and a previous operation (OR, 2.0; 95% CI = 1.0-4.4) were significantly associated with deep or organ/space infections. These results demonstrate additional factors that increase the risk of developing SSI. Deep and organ/space infections have a different risk profile. This information should guide clinicians in their assessment of SSI risk and should identify targets for intervention to decrease the incidence of SSI.

Use of Medicare claims to rank hospitals by surgical site infection risk following coronary artery bypass graft surgery.

PubMed

Huang, Susan S; Placzek, Hilary; Livingston, James; Ma, Allen; Onufrak, Fallon; Lankiewicz, Julie; Kleinman, Ken; Bratzler, Dale; Olsen, Margaret A; Lyles, Rosie; Khan, Yosef; Wright, Paula; Yokoe, Deborah S; Fraser, Victoria J; Weinstein, Robert A; Stevenson, Kurt; Hooper, David; Vostok, Johanna; Datta, Rupak; Nsa, Wato; Platt, Richard

2011-08-01

To evaluate whether longitudinal insurer claims data allow reliable identification of elevated hospital surgical site infection (SSI) rates. We conducted a retrospective cohort study of Medicare beneficiaries who underwent coronary artery bypass grafting (CABG) in US hospitals performing at least 80 procedures in 2005. Hospitals were assigned to deciles by using case mix-adjusted probabilities of having an SSI-related inpatient or outpatient claim code within 60 days of surgery. We then reviewed medical records of randomly selected patients to assess whether chart-confirmed SSI risk was higher in hospitals in the worst deciles compared with the best deciles. Fee-for-service Medicare beneficiaries who underwent CABG in these hospitals in 2005. We evaluated 114,673 patients who underwent CABG in 671 hospitals. In the best decile, 7.8% (958/12,307) of patients had an SSI-related code, compared with 24.8% (2,747/11,068) in the worst decile ([Formula: see text]). Medical record review confirmed SSI in 40% (388/980) of those with SSI-related codes. In the best decile, the chart-confirmed annual SSI rate was 3.2%, compared with 9.4% in the worst decile, with an adjusted odds ratio of SSI of 2.7 (confidence interval, 2.2-3.3; [Formula: see text]) for CABG performed in a worst-decile hospital compared with a best-decile hospital. Claims data can identify groups of hospitals with unusually high or low post-CABG SSI rates. Assessment of claims is more reproducible and efficient than current surveillance methods. This example of secondary use of routinely recorded electronic health information to assess quality of care can identify hospitals that may benefit from prevention programs.

Intensive postoperative glucose control reduces the surgical site infection rates in gynecologic oncology patients.

PubMed

Al-Niaimi, Ahmed N; Ahmed, Mostafa; Burish, Nikki; Chackmakchy, Saygin A; Seo, Songwon; Rose, Stephen; Hartenbach, Ellen; Kushner, David M; Safdar, Nasia; Rice, Laurel; Connor, Joseph

2015-01-01

SSI rates after gynecologic oncology surgery vary from 5% to 35%, but are up to 45% in patients with diabetes mellitus (DM). Strict postoperative glucose control by insulin infusion has been shown to lower morbidity, but not specifically SSI rates. Our project studied continuous postoperative insulin infusion for 24h for gynecologic oncology patients with DM and hyperglycemia with a target blood glucose of <139 mL/dL and a primary outcome of the protocol's impact on SSI rates. We compared SSI rates retrospectively among three groups. Group 1 was composed of patients with DM whose blood glucose was controlled with intermittent subcutaneous insulin injections. Group 2 was composed of patients with DM and postoperative hyperglycemia whose blood glucose was controlled by insulin infusion. Group 3 was composed of patients with neither DM nor hyperglycemia. We controlled for all relevant factors associated with SSI. We studied a total of 372 patients. Patients in Group 2 had an SSI rate of 26/135 (19%), similar to patients in Group 3 whose rate was 19/89 (21%). Both were significantly lower than the SSI rate (43/148, 29%) of patients in Group 1. This reduction of 35% is significant (p = 0.02). Multivariate analysis showed an odd ratio = 0.5 (0.28-0.91) in reducing SSI rates after instituting this protocol. Initiating intensive glycemic control for 24h after gynecologic oncology surgery in patients with DM and postoperative hyperglycemia lowers the SSI rate by 35% (OR = 0.5) compared to patients receiving intermittent sliding scale insulin and to a rate equivalent to non-diabetics. Copyright © 2014. Published by Elsevier Inc.

Combination of Oral Antibiotics and Mechanical Bowel Preparation Reduces Surgical Site Infection in Colorectal Surgery.

PubMed

Ohman, Kerri A; Wan, Leping; Guthrie, Tracey; Johnston, Bonnie; Leinicke, Jennifer A; Glasgow, Sean C; Hunt, Steven R; Mutch, Matthew G; Wise, Paul E; Silviera, Matthew L

2017-10-01

Surgical site infections (SSI) are a common complication after colorectal surgery. An infection prevention bundle (IPB) was implemented to improve outcomes. A standardized IPB that included the administration of oral antibiotics with a mechanical bowel preparation, preoperative shower with chlorhexidine, hair removal and skin preparation in holding, antibiotic wound irrigation, and a "clean-closure" protocol was implemented in January 2013. Data from the American College of Surgeons NSQIP were analyzed at a single academic institution to compare pre-IPB and post-IPB SSI rates. In January 2014, a prospective database was implemented to determine compliance with individual IPB elements and their effect on outcomes. For the 24 months pre-IPB, the overall SSI rate was 19.7%. During the 30 months after IPB implementation, the SSI rate decreased to 8.2% (p < 0.0001). A subset of 307 patients was identified in both NSQIP and our prospective compliance databases. Elements of IPB associated with decreased SSI rates included preoperative shower with chlorhexidine (4.6% vs 16.2%; p = 0.005), oral antibiotics (3.4% vs 15.4%; p < 0.001), and mechanical bowel preparation (4.4% vs 14.3%; p = 0.008). Patients who received a full bowel preparation of both oral antibiotics and a mechanical bowel preparation had a 2.7% SSI rate compared with 15.8% for all others (p < 0.001). On multivariate analysis, full bowel preparation was independently associated with significantly fewer SSI (adjusted odds ratio 0.2; 95% CI 0.1 to 0.9; p = 0.006). Implementation of an IPB was successful in decreasing SSI rates in colorectal surgery patients. The combination of oral antibiotics with a mechanical bowel preparation was the strongest predictor of decreased SSI. Copyright © 2017 American College of Surgeons. All rights reserved.

Surgical site infection after central venous catheter-related infection in cardiac surgery. Analysis of a cohort of 7557 patients.

PubMed

Le Guillou, V; Tavolacci, M-P; Baste, J-M; Hubscher, C; Bedoit, E; Bessou, J-P; Litzler, P-Y

2011-11-01

The aim of this study was to establish the relationship between the occurrence of a surgical site infection (SSI) and the presence of a central venous catheter-related infection (CVCRI). The Department of Thoracic and Cardiovascular Surgery, University Hospital, Rouen, has carried out a prospective epidemiological survey of all nosocomial infections (pneumonia, SSI and CVCRI) since 1997. The study group included all consecutive patients who underwent cardiac surgery over a 10-year period from 1997 to 2007. A nested case-control study was conducted to identify the risk factors for SSI after CVCRI. Cases were patients with SSI after CVCRI and controls were randomized from patients who presented with CVCRI not followed by SSI. In total, 7557 patients were included and 133 SSIs (1.7%) were identified. The rate of superficial SSI was 0.7% [95% confidence interval (CI): 0.5-0.9] and of mediastinitis was 1.0% (95% CI: 0.8-1.2). Among the 133 cases of SSI, 12 (9.0%; 95% CI: 5.0-14.8) occurred after a CVCRI with identical micro-organisms. CVCRI [adjusted odds ratio (aOR): 5.2; 95% CI: 3.2-8.5], coronary artery bypass grafting (aOR: 2.9; 95% CI: 1.6-5.2), and obesity (aOR: 11.4; 95% CI: 1.0-130.1) were independent factors associated with SSI. The new finding of this study is that patients with CVCRI were 5.2 times more likely to develop SSI compared to patients without CVCRI. Copyright © 2011 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

Improving Cardiac Surgical Site Infection Reporting and Prevention By Using Registry Data for Case Ascertainment.

PubMed

Nayar, Vaidehi; Kennedy, Andrea; Pappas, Janine; Atchley, Krista D; Field, Cynthia; Smathers, Sarah; Teszner, Eva E; Sammons, Julia S; Coffin, Susan E; Gerber, Jeffrey S; Spray, Thomas L; Steven, James M; Bell, Louis M; Forrer, Joan; Gonzalez, Fernando; Chi, Albert; Nieczpiel, William J; Martin, John N; Gaynor, J William

2016-01-01

The use of administrative data for surgical site infection (SSI) surveillance leads to inaccurate reporting of SSI rates [1]. A quality improvement (QI) initiative was conducted linking clinical registry and administrative databases to improve reporting and reduce the incidence of SSI [2]. At our institution, The Society of Thoracic Surgeons Congenital Heart Surgery Database (STS-CHSD) and infection surveillance database (ISD) were linked to the enterprise data warehouse containing electronic health record (EHR) billing data. A data visualization tool was created to (1) use the STS-CHSD for case ascertainment, (2) resolve discrepancies between the databases, and (3) assess impact of QI initiatives, including wound alert reports, bedside reviews, prevention bundles, and billing coder education. Over the 24-month study period, 1,715 surgical cases were ascertained according to the STS-CHSD clinical criteria, with 23 SSIs identified through the STS-CHSD, 20 SSIs identified through the ISD, and 32 SSIs identified through the billing database. The rolling 12-month STS-CHSD SSI rate decreased from 2.73% (21 of 769 as of January 2013) to 1.11% (9 of 813 as of December 2014). Thirty reporting discrepancies were reviewed to ensure accuracy. Workflow changes facilitated communication and improved adjudication of suspected SSIs. Billing coder education increased coding accuracy and narrowed variation between the 3 SSI sources. The data visualization tool demonstrated temporal relationships between QI initiatives and SSI rate reductions. Linkage of registry and infection control surveillance data with the EHR improves SSI surveillance. The visualization tool and workflow changes facilitated communication, SSI adjudication, and assessment of the QI initiatives. Implementation of these initiatives was associated with decreased SSI rates. Copyright © 2016 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Effects of hydrology, watershed size, and agricultural practices on sediment yields in two river basins in Iowa and Mississippi

USGS Publications Warehouse

Merten, Gustavo Henrique; Welch, Heather L.; Tomer, M.D.

2016-01-01

The specific sediment yield (SSY) from watersheds is the result of the balance between natural, scale-dependent erosion and deposition processes, but can be greatly altered by human activities. In general, the SSY decreases along the course of a river as sediments are trapped in alluvial plains and other sinks. However, this relation between SSY and basin area can actually be an increasing one when there is a predominance of channel erosion relative to hillslope erosion. The US Geological Survey (USGS) conducted a study of suspended sediment in the Iowa River basin (IRB), Iowa, and the Yazoo River basin (YRB), Mississippi, from 2006 through 2008. Within each river basin, the SSY from four largely agricultural watersheds of various sizes (2.3 to 35,000 km2 [0.9 to 13,513 mi2]) was investigated. In the smallest watersheds, YRB sites had greater SSY compared to IRB sites due to higher rain erosivity, more erodible soils, more overland flow, and fluvial geomorphological differences. Watersheds in the YRB showed a steady decrease in SSY with increasing drainage basin area, whereas in the IRB, the maximum SSY occurred at the 30 to 500 km2 (11.6 to 193 mi2) scale. Subsurface tile drainage and limits to channel downcutting restrict the upstream migration of sediment sources in the IRB. Nevertheless, by comparing the SSY-basin size scaling relationships with estimated rates of field erosion under conservation and conventional tillage treatments reported in previous literature, we show evidence that the SSY-basin size relationship in both the IRB and YRB remain impacted by historical erosion rates that occurred prior to conservation efforts.

Does Minimally Invasive Spine Surgery Minimize Surgical Site Infections?

PubMed

Kulkarni, Arvind Gopalrao; Patel, Ravish Shammi; Dutta, Shumayou

2016-12-01

Retrospective review of prospectively collected data. To evaluate the incidence of surgical site infections (SSIs) in minimally invasive spine surgery (MISS) in a cohort of patients and compare with available historical data on SSI in open spinal surgery cohorts, and to evaluate additional direct costs incurred due to SSI. SSI can lead to prolonged antibiotic therapy, extended hospitalization, repeated operations, and implant removal. Small incisions and minimal dissection intrinsic to MISS may minimize the risk of postoperative infections. However, there is a dearth of literature on infections after MISS and their additional direct financial implications. All patients from January 2007 to January 2015 undergoing posterior spinal surgery with tubular retractor system and microscope in our institution were included. The procedures performed included tubular discectomies, tubular decompressions for spinal stenosis and minimal invasive transforaminal lumbar interbody fusion (TLIF). The incidence of postoperative SSI was calculated and compared to the range of cited SSI rates from published studies. Direct costs were calculated from medical billing for index cases and for patients with SSI. A total of 1,043 patients underwent 763 noninstrumented surgeries (discectomies, decompressions) and 280 instrumented (TLIF) procedures. The mean age was 52.2 years with male:female ratio of 1.08:1. Three infections were encountered with fusion surgeries (mean detection time, 7 days). All three required wound wash and debridement with one patient requiring unilateral implant removal. Additional direct cost due to infection was $2,678 per 100 MISS-TLIF. SSI increased hospital expenditure per patient 1.5-fold after instrumented MISS. Overall infection rate after MISS was 0.29%, with SSI rate of 0% in non-instrumented MISS and 1.07% with instrumented MISS. MISS can markedly reduce the SSI rate and can be an effective tool to minimize hospital costs.

Derivation and Validation of the Surgical Site Infections Risk Model Using Health Administrative Data.

PubMed

van Walraven, Carl; Jackson, Timothy D; Daneman, Nick

2016-04-01

OBJECTIVE Surgical site infections (SSIs) are common hospital-acquired infections. Tracking SSIs is important to monitor their incidence, and this process requires primary data collection. In this study, we derived and validated a method using health administrative data to predict the probability that a person who had surgery would develop an SSI within 30 days. METHODS All patients enrolled in the National Surgical Quality Improvement Program (NSQIP) from 2 sites were linked to population-based administrative datasets in Ontario, Canada. We derived a multivariate model, stratified by surgical specialty, to determine the independent association of SSI status with patient and hospitalization covariates as well as physician claim codes. This SSI risk model was validated in 2 cohorts. RESULTS The derivation cohort included 5,359 patients with a 30-day SSI incidence of 6.0% (n=118). The SSI risk model predicted the probability that a person had an SSI based on 7 covariates: index hospitalization diagnostic score; physician claims score; emergency visit diagnostic score; operation duration; surgical service; and potential SSI codes. More than 90% of patients had predicted SSI risks lower than 10%. In the derivation group, model discrimination and calibration was excellent (C statistic, 0.912; Hosmer-Lemeshow [H-L] statistic, P=.47). In the 2 validation groups, performance decreased slightly (C statistics, 0.853 and 0.812; H-L statistics, 26.4 [P=.0009] and 8.0 [P=.42]), but low-risk patients were accurately identified. CONCLUSION Health administrative data can effectively identify postoperative patients with a very low risk of surgical site infection within 30 days of their procedure. Records of higher-risk patients can be reviewed to confirm SSI status.

Short Operative Duration and Surgical Site Infection Risk in Hip and Knee Arthroplasty Procedures

PubMed Central

Dicks, Kristen V.; Baker, Arthur W.; Durkin, Michael J.; Anderson, Deverick J.; Moehring, Rebekah W.; Chen, Luke F.; Sexton, Daniel J.; Weber, David J.; Lewis, Sarah S.

2016-01-01

OBJECTIVE To determine the association (1) between shorter operative duration and surgical site infection (SSI) and (2) between surgeon median operative duration and SSI risk among first-time hip and knee arthroplasties. DESIGN Retrospective cohort study SETTING A total of 43 community hospitals located in the southeastern United States. PATIENTS Adults who developed SSIs according to National Healthcare Safety Network criteria within 365 days of first-time knee or hip arthroplasties performed between January 1, 2008 and December 31, 2012. METHODS Log-binomial regression models estimated the association (1) between operative duration and SSI outcome and (2) between surgeon median operative duration and SSI outcome. Hip and knee arthroplasties were evaluated in separate models. Each model was adjusted for American Society of Anesthesiology score and patient age. RESULTS A total of 25,531 hip arthroplasties and 42,187 knee arthroplasties were included in the study. The risk of SSI in knee arthroplasties with an operative duration shorter than the 25th percentile was 0.40 times the risk of SSI in knee arthroplasties with an operative duration between the 25th and 75th percentile (risk ratio [RR], 0.40; 95% confidence interval [CI], 0.38–0.56; P <.01). Short operative duration did not demonstrate significant association with SSI for hip arthroplasties (RR, 1.04; 95% CI, 0.79–1.37; P =.36). Knee arthroplasty surgeons with shorter median operative durations had a lower risk of SSI than surgeons with typical median operative durations (RR, 0.52; 95% CI, 0.43–0.64; P <.01). CONCLUSIONS Short operative durations were not associated with a higher SSI risk for knee or hip arthroplasty procedures in our analysis. PMID:26391277

Long-term housing subsidies and SSI/SSDI income: Creating health-promoting contexts for families experiencing housing instability with disabilities.

PubMed

Glendening, Zachary S; McCauley, Erin; Shinn, Marybeth; Brown, Scott R

2018-04-01

Though disability and housing instability are discussed separately in public health literature, few studies address families at their intersection. As a result, little is known about families who experience both homelessness and disability, how many receive disability benefits like SSI and SSDI, or the influence of those benefits on health-promoting outcomes like housing stability and self-sufficiency. Moreover, no previous research compares the ability of different housing and service interventions to increase disability benefit access. We examine relationships between disabilities and SSI/SSDI income reported when families enter emergency shelters and later health-promoting outcomes (housing stability and self-sufficiency) and how housing interventions affect SSI/SSDI receipt. Families in the (name removed) Study (N = 1857) were interviewed in emergency shelters, randomly offered of one of three housing interventions or usual care (i.e., no immediate referral to any intervention beyond shelter), and re-interviewed 20 months later. A third of families reported a disability at shelter entry. SSI/SSDI coverage of these families increased nearly 10% points over 20 months but never exceeded 40%. Disabilities predicted greater housing instability, food insecurity, and economic stress and less work and income. Among families reporting disabilities, SSI/SSDI receipt predicted fewer returns to emergency shelter, and more income despite less work. Offers of long-term housing subsidies increased SSI/SSDI receipt. Many families experiencing homelessness have disabilities; those receiving SSI/SSDI benefits have better housing and income outcomes. Providing families experiencing homelessness with long-term housing subsidies and SSI/SSDI could improve public health. Copyright © 2017 Elsevier Inc. All rights reserved.

Variable Case Detection and Many Unreported Cases of Surgical-Site Infection Following Colon Surgery and Abdominal Hysterectomy in a Statewide Validation.

PubMed

Calderwood, Michael S; Huang, Susan S; Keller, Vicki; Bruce, Christina B; Kazerouni, N Neely; Janssen, Lynn

2017-09-01

OBJECTIVE To assess hospital surgical-site infection (SSI) identification and reporting following colon surgery and abdominal hysterectomy via a statewide external validation METHODS Infection preventionists (IPs) from the California Department of Public Health (CDPH) performed on-site SSI validation for surgical procedures performed in hospitals that voluntarily participated. Validation involved chart review of SSI cases previously reported by hospitals plus review of patient records flagged for review by claims codes suggestive of SSI. We assessed the sensitivity of traditional surveillance and the added benefit of claims-based surveillance. We also evaluated the positive predictive value of claims-based surveillance (ie, workload efficiency). RESULTS Upon validation review, CDPH IPs identified 239 SSIs following colon surgery at 42 hospitals and 76 SSIs following abdominal hysterectomy at 34 hospitals. For colon surgery, traditional surveillance had a sensitivity of 50% (47% for deep incisional or organ/space [DI/OS] SSI), compared to 84% (88% for DI/OS SSI) for claims-based surveillance. For abdominal hysterectomy, traditional surveillance had a sensitivity of 68% (67% for DI/OS SSI) compared to 74% (78% for DI/OS SSI) for claims-based surveillance. Claims-based surveillance was also efficient, with 1 SSI identified for every 2 patients flagged for review who had undergone abdominal hysterectomy and for every 2.6 patients flagged for review who had undergone colon surgery. Overall, CDPH identified previously unreported SSIs in 74% of validation hospitals performing colon surgery and 35% of validation hospitals performing abdominal hysterectomy. CONCLUSIONS Claims-based surveillance is a standardized approach that hospitals can use to augment traditional surveillance methods and health departments can use for external validation. Infect Control Hosp Epidemiol 2017;38:1091-1097.

Exploring preservice elementary teachers' critique and adaptation of science curriculum materials in respect to socioscientific issues

NASA Astrophysics Data System (ADS)

Forbes, Cory T.; Davis, Elizabeth A.

2008-09-01

The work presented here represents a preliminary effort undertaken to address the role of teachers in supporting students’ learning and decision-making about socioscientific issues (SSI) by characterizing preservice elementary teachers’ critique and adaptation of SSI-based science curriculum materials and identifying factors that serve to mediate this process. Four undergraduate preservice elementary teachers were studied over the course of one semester. Results indicate that the teachers navigated multiple learning goals, as well as their own subject-matter knowledge, informal reasoning about SSI, and role identity, in their critique and adaptation of SSI-oriented science instructional materials. Implications for science teacher education and the design of curriculum materials in respect to SSI are discussed.

Interannual, seasonal and diurnal Mars surface environmental cycles observed from Viking to Curiosity

NASA Astrophysics Data System (ADS)

Martinez, German; Vicente-Retortillo, Álvaro; Kemppinen, Osku; Fischer, Erik; Fairen, Alberto G.; Guzewich, Scott David; Haberle, Robert; Lemmon, Mark T.; Newman, Claire E.; Renno, Nilton O.; Richardson, Mark I.; Smith, Michael D.; De la Torre, Manuel; Vasavada, Ashwin R.

2016-10-01

We analyze in-situ environmental data from the Viking landers to the Curiosity rover to estimate atmospheric pressure, near-surface air and ground temperature, relative humidity, wind speed and dust opacity with the highest confidence possible. We study the interannual, seasonal and diurnal variability of these quantities at the various landing sites over a span of more than twenty Martian years to characterize the climate on Mars and its variability. Additionally, we characterize the radiative environment at the various landing sites by estimating the daily UV irradiation (also called insolation and defined as the total amount of solar UV energy received on flat surface during one sol) and by analyzing its interannual and seasonal variability.In this study we use measurements conducted by the Viking Meteorology Instrument System (VMIS) and Viking lander camera onboard the Viking landers (VL); the Atmospheric Structure Instrument/Meteorology (ASIMET) package and the Imager for Mars Pathfinder (IMP) onboard the Mars Pathfinder (MPF) lander; the Miniature Thermal Emission Spectrometer (Mini-TES) and Pancam instruments onboard the Mars Exploration Rovers (MER); the Meteorological Station (MET), Thermal Electrical Conductivity Probe (TECP) and Phoenix Surface Stereo Imager (SSI) onboard the Phoenix (PHX) lander; and the Rover Environmental Monitoring Station (REMS) and Mastcam instrument onboard the Mars Science Laboratory (MSL) rover.A thorough analysis of in-situ environmental data from past and present missions is important to aid in the selection of the Mars 2020 landing site. We plan to extend our analysis of Mars surface environmental cycles by using upcoming data from the Temperature and Wind sensors (TWINS) instrument onboard the InSight mission and the Mars Environmental Dynamics Analyzer (MEDA) instrument onboard the Mars 2020 mission.

20 CFR 416.203 - Initial determinations of SSI eligibility.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Initial determinations of SSI eligibility. 416.203 Section 416.203 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility General § 416.203 Initial determinations of SSI...

20 CFR 416.203 - Initial determinations of SSI eligibility.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Initial determinations of SSI eligibility. 416.203 Section 416.203 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility General § 416.203 Initial determinations of SSI...

20 CFR 416.203 - Initial determinations of SSI eligibility.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Initial determinations of SSI eligibility. 416.203 Section 416.203 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility General § 416.203 Initial determinations of SSI...

20 CFR 416.203 - Initial determinations of SSI eligibility.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Initial determinations of SSI eligibility. 416.203 Section 416.203 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility General § 416.203 Initial determinations of SSI...

20 CFR 416.203 - Initial determinations of SSI eligibility.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Initial determinations of SSI eligibility. 416.203 Section 416.203 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility General § 416.203 Initial determinations of SSI...

Modular, Autonomous Command and Data Handling Software with Built-In Simulation and Test

NASA Technical Reports Server (NTRS)

Cuseo, John

2012-01-01

The spacecraft system that plays the greatest role throughout the program lifecycle is the Command and Data Handling System (C&DH), along with the associated algorithms and software. The C&DH takes on this role as cost driver because it is the brains of the spacecraft and is the element of the system that is primarily responsible for the integration and interoperability of all spacecraft subsystems. During design and development, many activities associated with mission design, system engineering, and subsystem development result in products that are directly supported by the C&DH, such as interfaces, algorithms, flight software (FSW), and parameter sets. A modular system architecture has been developed that provides a means for rapid spacecraft assembly, test, and integration. This modular C&DH software architecture, which can be targeted and adapted to a wide variety of spacecraft architectures, payloads, and mission requirements, eliminates the current practice of rewriting the spacecraft software and test environment for every mission. This software allows missionspecific software and algorithms to be rapidly integrated and tested, significantly decreasing time involved in the software development cycle. Additionally, the FSW includes an Onboard Dynamic Simulation System (ODySSy) that allows the C&DH software to support rapid integration and test. With this solution, the C&DH software capabilities will encompass all phases of the spacecraft lifecycle. ODySSy is an on-board simulation capability built directly into the FSW that provides dynamic built-in test capabilities as soon as the FSW image is loaded onto the processor. It includes a six-degrees- of-freedom, high-fidelity simulation that allows complete closed-loop and hardware-in-the-loop testing of a spacecraft in a ground processing environment without any additional external stimuli. ODySSy can intercept and modify sensor inputs using mathematical sensor models, and can intercept and respond to actuator commands. ODySSy integration is unique in that it allows testing of actual mission sequences on the flight vehicle while the spacecraft is in various stages of assembly, test, and launch operations all without any external support equipment or simulators. The ODySSy component of the FSW significantly decreases the time required for integration and test by providing an automated, standardized, and modular approach to integrated avionics and component interface and functional verification. ODySSy further provides the capability for on-orbit support in the form of autonomous mission planning and fault protection.

Predicting surgical site infection after spine surgery: a validated model using a prospective surgical registry.

PubMed

Lee, Michael J; Cizik, Amy M; Hamilton, Deven; Chapman, Jens R

2014-09-01

The impact of surgical site infection (SSI) is substantial. Although previous study has determined relative risk and odds ratio (OR) values to quantify risk factors, these values may be difficult to translate to the patient during counseling of surgical options. Ideally, a model that predicts absolute risk of SSI, rather than relative risk or OR values, would greatly enhance the discussion of safety of spine surgery. To date, there is no risk stratification model that specifically predicts the risk of medical complication. The purpose of this study was to create and validate a predictive model for the risk of SSI after spine surgery. This study performs a multivariate analysis of SSI after spine surgery using a large prospective surgical registry. Using the results of this analysis, this study will then create and validate a predictive model for SSI after spine surgery. The patient sample is from a high-quality surgical registry from our two institutions with prospectively collected, detailed demographic, comorbidity, and complication data. An SSI that required return to the operating room for surgical debridement. Using a prospectively collected surgical registry of more than 1,532 patients with extensive demographic, comorbidity, surgical, and complication details recorded for 2 years after the surgery, we identified several risk factors for SSI after multivariate analysis. Using the beta coefficients from those regression analyses, we created a model to predict the occurrence of SSI after spine surgery. We split our data into two subsets for internal and cross-validation of our model. We created a predictive model based on our beta coefficients from our multivariate analysis. The final predictive model for SSI had a receiver-operator curve characteristic of 0.72, considered to be a fair measure. The final model has been uploaded for use on SpineSage.com. We present a validated model for predicting SSI after spine surgery. The value in this model is that it gives the user an absolute percent likelihood of SSI after spine surgery based on the patient's comorbidity profile and invasiveness of surgery. Patients are far more likely to understand an absolute percentage, rather than relative risk and confidence interval values. A model such as this is of paramount importance in counseling patients and enhancing the safety of spine surgery. In addition, a tool such as this can be of great use particularly as health care trends toward pay for performance, quality metrics (such as SSI), and risk adjustment. To facilitate the use of this model, we have created a Web site (SpineSage.com) where users can enter patient data to determine likelihood for SSI. Copyright © 2014 Elsevier Inc. All rights reserved.

Supplemental Security Income Benefits for Mental Disorders.

PubMed

Perrin, James M; Houtrow, Amy; Kelleher, Kelly; Hoagwood, Kimberly; Stein, Ruth E K; Zima, Bonnie

2016-07-01

The Supplemental Security Income Program (SSI) provides financial support to low-income households with children and youth with severe disabilities. The program included children when it began in the early 1970s. The numbers of children receiving SSI benefits increased substantially in the early 1990s, in part through an expansion of the listings of mental health conditions with which children could become eligible. Over the past 20 years, larger numbers of children have received SSI benefits for mental disorders, and these increases have led to questions from the press and Congress regarding these numbers. Do they indicate more of an increase in mental disorders among SSI children than in the general population? The National Academy of Medicine (NAM; formerly the Institute of Medicine) convened a study panel to examine what is known about mental disorders among the child SSI population and how that compares with evidence about mental disorders in children in general. The NAM report provides detailed information about how SSI works, about the changing numbers of children receiving SSI for mental disorders, and some comparisons with other evidence about rising rates of mental disorders in the general population and especially among children living in poverty. The report indicates that increasing numbers of children with mental disorders in SSI mirror similar increases in the population in general. This article summarizes key evidence from the NAM report and suggests the implications for pediatricians. Copyright © 2016 by the American Academy of Pediatrics.

From the American Academy of Pediatrics: Policy statements--Supplemental Security Income (SSI) for children and youth with disabilities.

PubMed

2009-12-01

The Supplemental Security Income (SSI) program remains an important source of financial support for low-income families of children with special health care needs and disabling conditions. In most states, SSI eligibility also qualifies children for the state Medicaid program, providing access to health care services. The Social Security Administration (SSA), which administers the SSI program, considers a child disabled under SSI if there is a medically determinable physical or mental impairment or combination of impairments that results in marked and severe functional limitations. The impairment(s) must be expected to result in death or have lasted or be expected to last for a continuous period of at least 12 months. The income and assets of families of children with disabilities are also considered when determining financial eligibility. When an individual with a disability becomes an adult at 18 years of age, the SSA considers only the individual's income and assets. The SSA considers an adult to be disabled if there is a medically determinable impairment (or combination of impairments) that prevents substantial gainful activity for at least 12 continuous months. SSI benefits are important for youth with chronic conditions who are transitioning to adulthood. The purpose of this statement is to provide updated information about the SSI medical and financial eligibility criteria and the disability-determination process. This statement also discusses how pediatricians can help children and youth when they apply for SSI benefits.

7 CFR 273.20 - SSI cash-out.

Code of Federal Regulations, 2010 CFR

2010-01-01

... specifically increased to include the value of the food stamp allotment. (b) Receipt of SSI benefits. In... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE FOOD STAMP AND FOOD DISTRIBUTION PROGRAM CERTIFICATION OF ELIGIBLE HOUSEHOLDS § 273.20 SSI cash-out. (a...

Chemical characteristics of Northeast Asian fly ash particles: Implications for their long-range transportation

NASA Astrophysics Data System (ADS)

Inoue, Jun; Momose, Azusa; Okudaira, Takamoto; Murakami-Kitase, Akiko; Yamazaki, Hideo; Yoshikawa, Shusaku

2014-10-01

The chemical compositions of fly ash particles emitted in Northeast Asia were studied to better understand the long-range transportation of atmospheric pollutants. We examined the compositions of spheroidal carbonaceous particles (SCPs), a type of fly ash from several to ˜20 μm in diameter found in surface sediments in or near the main industrial cities of Japan, China, South Korea, and Taiwan. SCPs from different countries were found to vary; SCPs from Japan and South Korea were characterized by low Ti/Si and high S/Si ratios, whereas SCPs in China exhibited high Ti/Si and low S/Si ratios and particles from Taiwan showed high Ti/Si and S/Si ratios. We also examined the SCPs found in remote islands in the Sea of Japan, at least 100 km from any industrial city. On the basis of their chemical compositions, these SCPs were classified as Japan and Korea, China, and Taiwan types using discriminant analysis. The results indicated that 30-50% of the particles found in these islands were assigned to the China type, suggesting that most of these SCPs were probably transported from Chinese industrial regions to these islands. It implies that even large particulate pollutants of ˜10 μm, such as SCPs, could be transported long distances of ˜1000 km.

Two New Hot Spots on Io

NASA Image and Video Library

1998-03-26

The Near-Infrared Mapping Spectrometer (NIMS) on Galileo obtained this image of half of Io's disk in darkness on September 19, 1997. This image, at 5 microns, shows several hot spots on Io, which are volcanic regions of enhanced thermal emission. The area shown is part of the leading hemisphere of Io. Two new hot spots are shown and indicated in the image (New, and Shamshu). Neither of these hot spots were seen by NIMS or the Solid State Imaging Experiment, (SSI) prior to this observation, becoming only recently active. Several other previously known hot spots are labelled in the image. Galileo was at a distance of 342,000 km from Io when this observation was made. http://photojournal.jpl.nasa.gov/catalog/PIA01226

Suppression of starch synthase I expression affects the granule morphology and granule size and fine structure of starch in wheat endosperm

PubMed Central

2014-01-01

Studies in Arabidopsis and rice suggest that manipulation of starch synthase I (SSI) expression in wheat may lead to the production of wheat grains with novel starch structure and properties. This work describes the suppression of SSI expression in wheat grains using RNAi technology, which leads to a low level of enzymatic activity for SSI in the developing endosperm, and a low abundance of SSI protein inside the starch granules of mature grains. The amylopectin fraction of starch from the SSI suppressed lines showed an increased frequency of very short chains (degree of polymerization, dp 6 and 7), a lower proportion of short chains (dp 8–12), and more intermediate chains (dp 13–20) than in the grain from their negative segregant lines. In the most severely affected line, amylose content was significantly increased, the morphology of starch granules was changed, and the proportion of B starch granules was significantly reduced. The change of the fine structure of the starch in the SSI-RNAi suppression lines alters the gelatinization temperature, swelling power, and viscosity of the starch. This work demonstrates that the roles of SSI in the determination of starch structure and properties are similar among different cereals and Arabidopsis. PMID:24634486

Administrative data measured surgical site infection probability within 30 days of surgery in elderly patients.

PubMed

van Walraven, Carl; Jackson, Timothy D; Daneman, Nick

2016-09-01

Elderly patients are inordinately affected by surgical site infections (SSIs). This study derived and internally validated a model that used routinely collected health administrative data to measure the probability of SSI in elderly patients within 30 days of surgery. All people exceeding 65 years undergoing surgery from two hospitals with known SSI status were linked to population-based administrative data sets in Ontario, Canada. We used bootstrap methods to create a multivariate model that used health administrative data to predict the probability of SSI. Of 3,436 patients, 177 (5.1%) had an SSI. The Elderly SSI Risk Model included six covariates: number of distinct physician fee codes within 30 days of surgery; presence or absence of a postdischarge prescription for an antibiotic; presence or absence of three diagnostic codes; and a previously derived score that gauged SSI risk based on procedure codes. The model was highly explanatory (Nagelkerke's R 2 , 0.458), strongly discriminative (C statistic, 0.918), and well calibrated (calibration slope, 1). Health administrative data can effectively determine 30-day risk of SSI risk in elderly patients undergoing a broad assortment of surgeries. External validation is necessary before this can be routinely used to monitor SSIs in the elderly. Copyright © 2016 Elsevier Inc. All rights reserved.

A closer look at Chaos on Europa

NASA Technical Reports Server (NTRS)

1998-01-01

This mosaic of the Conamara Chaos region on Jupiter's moon, Europa, clearly indicates relatively recent resurfacing of Europa's surface. Irregularly shaped blocks of water ice were formed by the break up and movement of the existing crust. The blocks were shifted, rotated, and even tipped and partially submerged within a mobile material that was either liquid water, warm mobile ice, or an ice and water slush. The presence of young fractures cutting through this region indicates that the surface froze again into solid, brittle ice.

The background image in this picture was taken during Galileo's sixth orbit of Jupiter in February, 1997. Five very high resolution images which were taken during the spacecraft's twelfth orbit in December, 1997 provide an even closer look at some of the details. This mosaic shows some of the high resolution data inset into the context of this tumultuous region.

North is to the top of the picture, and the sun illuminates the scene from the east (right). The picture, centered at 9 degrees north latitude and 274 degrees west longitude, covers an area approximately 35 by 50 kilometers (20 by 30 miles). The finest details visible in the very high resolution insets are about 20 meters (22 yards) across, and in the background image, 100 meters (110 yards) across. The insets were taken on December 16, 1997, at ranges as close as 880 kilometers (550 miles) by the Solid State Imaging (SSI) system on NASA's Galileo spacecraft.

The Jet Propulsion Laboratory, Pasadena, CA manages the Galileo mission for NASA's Office of Space Science, Washington, DC. JPL is an operating division of California Institute of Technology (Caltech).

This image and other images and data received from Galileo are posted on the World Wide Web, on the Galileo mission home page at URL http://galileo.jpl.nasa.gov. Background information and educational context for the images can be found at URL http://www.jpl.nasa.gov/galileo/sepo

In vivo quantification of the shear modulus of the human Achilles tendon during passive loading using shear wave dispersion analysis.

PubMed

Helfenstein-Didier, C; Andrade, R J; Brum, J; Hug, F; Tanter, M; Nordez, A; Gennisson, J-L

2016-03-21

The shear wave velocity dispersion was analyzed in the Achilles tendon (AT) during passive dorsiflexion using a phase velocity method in order to obtain the tendon shear modulus (C 55). Based on this analysis, the aims of the present study were (i) to assess the reproducibility of the shear modulus for different ankle angles, (ii) to assess the effect of the probe locations, and (iii) to compare results with elasticity values obtained with the supersonic shear imaging (SSI) technique. The AT shear modulus (C 55) consistently increased with the ankle dorsiflexion (N = 10, p < 0.05). Furthermore, the technique showed a very good reproducibility (all standard error of the mean values <10.7 kPa and all coefficient of variation (CV) values ⩽ 0.05%). In addition, independently from the ankle dorsiflexion, the shear modulus was significantly higher in the proximal location compared to the more distal one. The shear modulus provided by SSI was always lower than C55 and the difference increased with the ankle dorsiflexion. However, shear modulus values provided by both methods were highly correlated (R = 0.84), indicating that the conventional shear wave elastography technique (SSI technique) can be used to compare tendon mechanical properties across populations. Future studies should determine the clinical relevance of the shear wave dispersion analysis, for instance in the case of tendinopathy or tendon tear.

The SATIRE-S model and why getting solar cycle spectral irradiance trends correct is so important

NASA Astrophysics Data System (ADS)

Ball, William; Haigh, Joanna; Krivova, Natalie; Unruh, Yvonne; Solanki, Sami

2014-05-01

There is currently a wide range of potential spectral solar irradiance (SSI) solar cycle (SC) amplitudes suggested by observations and models. Therefore, SSI SC changes are still not fully understood. The magnitude of the SC flux changes has a direct impact upon the temperature and chemistry of the Earth's atmosphere. To contribute to an understanding of the solar-climate connection, it is critical that we, as the solar community, communicate effectively with the climate community, providing uncertainties in SSI data and assessments of possible SSI options. We present the SATIRE-S reconstruction in the context of these SSI datasets. SATIRE-S is a physically based, consistent SSI reconstruction over the last three solar cycles. It shows different SC spectral variability at all wavelengths compared to the NRLSSI model, widely used in climate research. Most-importantly, SC changes in the ultra-violet (UV) can be twice as large in SATIRE-S as NRLSSI. Typically NRLSSI provides a lower limit of SC SSI UV variability. SORCE satellite observations provide SC magnitudes at the upper limit of variability, exceeding that of SATIRE-S by a factor of three at some UV wavelengths. There is currently no way to be certain if any of these three SSI datasets, or others, is correct. We also present the SSI datasets in terms of their impact on stratospheric ozone, within a 2D atmospheric model, as an example of why it is important to get SC changes correct. Using NRLSSI results in the 2D atmospheric model, we see a decrease in ozone concentration at all altitudes from solar maximum to minimum. SATIRE-S and SORCE/SOLSTICE observations instead show an increase in ozone concentration in the mesosphere. The magnitude of the increase in the mesosphere when using SOLSTICE also depends greatly upon the version of the data, which means that studies using different data versions of SOLSTICE may lead to different conclusions. These results highlight why an accurate understanding of SC SSI changes, and their uncertainties, are essential for the climate community that uses our work.

Surgical site infection after surgery to repair femoral neck fracture: a French multicenter retrospective study.

PubMed

Merrer, Jacques; Girou, Emmanuelle; Lortat-Jacob, Alain; Montravers, Philippe; Lucet, Jean-Christophe

2007-10-01

Femoral neck fracture is the most frequent orthopedic emergency among elderly persons. Despite a high prevalence of methicillin-resistant Staphylococcus aureus (MRSA) carriage in this population, no multicenter study of antibiotic prophylaxis practices and the rate and microbiological characteristics of surgical site infection (SSI) has been performed in France. Retrospective, multicenter cohort study. Twenty-two university and community hospitals in France. Each center provided data on 25 consecutive patients who underwent surgery for femoral neck fracture during the first quarter of 2005. Demographic, clinical, and follow-up characteristics were recorded, and most patients had a follow-up office visit or were involved in a telephone survey 1 year after surgery. These 22 centers provided data on 541 patients, 396 (73%) of whom were followed up 1 year after surgery. Of 504 (93%) patients for whom antibiotic prophylaxis was recorded, 433 (86%) received a cephalosporin. Twenty-two patients had an SSI, for a rate of 5.6% (95% confidence interval, 3.7-8.0). SSI was reported for 15 (6.9%) of patients who had a prosthesis placed and for 7 (3.9%) who underwent osteosynthesis (P=.27). SSI was diagnosed a median of 30 days after surgery (interquartile range, 21-41 days); 7 (32%) of these SSIs were superficial infections, and 15 (68%) were deep or organ-space infections. MRSA caused 7 SSIs (32%), Pseudomonas aeruginosa caused 5 (23%), other staphylococci caused 4 (18%), and other bacteria caused 2 (9%); the etiologic pathogen was unknown in 4 cases (18%). Reoperation was performed for 14 patients with deep or organ-space SSI, including 6 of 7 patients with MRSA SSI. The mortality rate 1 year after surgery was 20% overall but 50% among patients with SSI. In univariate analysis, only the National Nosocomial Infections Surveillance System risk index score was significantly associated with SSI (P=.006). SSI after surgery for femoral neck fracture is severe, and MRSA is the most frequently encountered etiologic pathogen. A large, multicenter prospective trial is necessary to determine whether the use of antibiotic prophylaxis effective against MRSA would decrease the SSI rate in this population.

Randomized clinical trial of negative pressure wound therapy for high-risk groin wounds in lower extremity revascularization.

PubMed

Lee, Kevin; Murphy, Patrick B; Ingves, Matthew V; Duncan, Audra; DeRose, Guy; Dubois, Luc; Forbes, Thomas L; Power, Adam

2017-12-01

The surgical site infection (SSI) rate in vascular surgery after groin incision for lower extremity revascularization can lead to significant morbidity and mortality. This trial was designed to study the effect of negative pressure wound therapy (NPWT) on SSI in closed groin wounds after lower extremity revascularization in patients at high risk for SSI. A single-center, randomized, controlled trial was performed at an academic tertiary medical center. Patients with previous femoral artery surgical exposure, body mass index of >30 kg/m 2 or the presence of ischemic tissue loss were classified as a high-risk patient for SSI. All wounds were closed primarily and patients were randomized to either NPWT or standard dressing. The primary outcome of the trial was postoperative 30-day SSI in the groin wound. The secondary outcomes included 90-day SSI, hospital duration of stay, readmissions or reoperations for SSI, and mortality. A total of 102 patients were randomized between August 2014 and December 2015. Patients were classified as at high risk owing to the presence of previous femoral artery cut down (29%), body mass index of >30 kg/m 2 (39%) or presence of ischemic tissue loss (32%). Revascularization procedures performed included femoral to distal artery bypass (57%), femoral endarterectomy (18%), femoral to femoral artery crossover (17%), and other procedures (8%). The primary outcome of 30-day SSI was 11% in NPWT group versus 19% in standard dressing group (P = .24). There was a statistically significant shorter mean duration of hospital stay in the NPWT group (6.4 days) compared with the standard group (8.9 days; P = .01). There was no difference in readmission or reoperation for SSI or mortality between the two groups. This study demonstrated a nonsignificant lower rate of groin SSI in high-risk revascularization patients with NPWT compared with standard dressing. Owing to a lower than expected infection rate, the study was underpowered to detect a difference at the prespecified level. The NPWT group did show significantly shorter mean hospital duration of stay compared with the standard dressing group. Copyright © 2017 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.

An economic model: value of antimicrobial-coated sutures to society, hospitals, and third-party payers in preventing abdominal surgical site infections.

PubMed

Singh, Ashima; Bartsch, Sarah M; Muder, Robert R; Lee, Bruce Y

2014-08-01

While the persistence of high surgical site infection (SSI) rates has prompted the advent of more expensive sutures that are coated with antimicrobial agents to prevent SSIs, the economic value of such sutures has yet to be determined. Using TreeAge Pro, we developed a decision analytic model to determine the cost-effectiveness of using antimicrobial sutures in abdominal incisions from the hospital, third-party payer, and societal perspectives. Sensitivity analyses systematically varied the risk of developing an SSI (range, 5%-20%), the cost of triclosan-coated sutures (range, $5-$25/inch), and triclosan-coated suture efficacy in preventing infection (range, 5%-50%) to highlight the range of costs associated with using such sutures. Triclosan-coated sutures saved $4,109-$13,975 (hospital perspective), $4,133-$14,297 (third-party payer perspective), and $40,127-$53,244 (societal perspective) per SSI prevented, when a surgery had a 15% SSI risk, depending on their efficacy. If the SSI risk was no more than 5% and the efficacy in preventing SSIs was no more than 10%, triclosan-coated sutures resulted in extra expenditure for hospitals and third-party payers (resulting in extra costs of $1,626 and $1,071 per SSI prevented for hospitals and third-party payers, respectively; SSI risk, 5%; efficacy, 10%). Our results suggest that switching to triclosan-coated sutures from the uncoated sutures can both prevent SSIs and save substantial costs for hospitals, third-party payers, and society, as long as efficacy in preventing SSIs is at least 10% and SSI risk is at least 10%.

Evaluation Intravenous Drip Cephazolin Prophylaxis of Breast Cancer Surgery Site Infection.

PubMed

Yang, Sufang; Liu, Guohua; Tang, Danling; Cai, De

2017-09-01

The efficacy of antibiotic prophylaxis for the prevention of surgical site infection (SSI) after breast cancer surgery remains uncertain. The authors of a recent Cochrane meta-analysis based on 15 randomized trials were unable to draw a definitive conclusion. The purpose of this study was to determine the effectiveness of prophylactic antibiotics for the prevention of SSI after breast cancer surgery and the risk factors for SSI. Breast cancer patients who underwent mastectomy at the authors' institution were enrolled in this study. All the patients give cephazolin by intravenous drip within 1 hour before surgery. Surgical site infection was defined using Centers for Disease Control criteria. Risk factors were abstracted from the electronic medical record. Pearson χ test, Student t test, and multivariable logistic regression were used for the analysis. Four hundred fifty-eight patients undergoing mastectomy were enrolled in this study, including 293 with intravenous drip cephazolin and 165 without. Among them, an overall SSI rate of 6.1% was observed; 4.2% of patients without prophylactic antibiotics developed SSI compared with 7.2% with antibiotics (P = 0.210). Factors associated with SSI were hypertension, diabetes, length of stay (d), age, and length of stay. Weight, duration of surgery, No. of drains, surgical procedure, and type of breast disease were not associated with increased SSI rates. Surgical site infection rates among patients who did and did not receive cephazolin after mastectomy had no significantly different. What is more, the authors should focus on advanced age, hypertension, diabetes, length of stay, and length of stay to decrease development of postoperative SSI rates.

Use of prophylactic postoperative antibiotics during surgical drain presence following mastectomy.

PubMed

Edwards, Brandy L; Stukenborg, George J; Brenin, David R; Schroen, Anneke T

2014-10-01

National guidelines recommend one dose of perioperative antibiotics for breast surgery and discourage postoperative continuation. However, reported skin and soft tissue infection (SSI) rates after mastectomy range from 1-26 %, higher than expected for clean cases. Utility of routine or selective postoperative antibiotic use for duration of drain presence following mastectomy remains uncertain. This study included all female patients who underwent mastectomy without reconstruction at our institution between 2005 and 2012. SSI was defined using CDC criteria or clinical diagnosis of cellulitis. Information on risk factors for infection (age, body mass index [BMI], smoking status, diabetes, steroid use), prior breast cancer treatment, drain duration, and antibiotic use was abstracted from medical records. Multivariable logistic regression was used to assess the association between postoperative antibiotic use and the occurrence of SSI, adjusting for concurrent risk factors. Among 480 patients undergoing mastectomy without reconstruction, 425 had sufficient documentation for analysis. Of these, 268 were prescribed antibiotics (63 %) at hospital discharge. An overall SSI rate of 7.3 % was observed, with 14 % of patients without postoperative antibiotics developing SSI compared with 3.4 % with antibiotics (p < 0.0001). Factors independently associated with SSI were smoking and advancing age. Diabetes, steroid use, BMI, prior breast surgery, neoadjuvant chemotherapy, prior radiation, concomitant axillary surgery, and drain duration were not associated with increased SSI rates. SSI rates among patients who did and did not receive postoperative antibiotics after mastectomy were significantly different, particularly among smokers and women of advanced age. These patient subgroups may warrant special consideration for postoperative antibiotics.

Use of Prophylactic Postoperative Antibiotics During Surgical Drain Presence Following Mastectomy

PubMed Central

Edwards, Brandy L.; Stukenborg, George J.; Brenin, David R.; Schroen, Anneke T.

2015-01-01

Background National guidelines recommend one dose of perioperative antibiotics for breast surgery and discourage postoperative continuation. However, reported skin and soft tissue infection (SSI) rates after mastectomy range from 1–26 %, higher than expected for clean cases. Utility of routine or selective postoperative antibiotic use for duration of drain presence following mastectomy remains uncertain. Methods This study included all female patients who underwent mastectomy without reconstruction at our institution between 2005 and 2012. SSI was defined using CDC criteria or clinical diagnosis of cellulitis. Information on risk factors for infection (age, body mass index [BMI], smoking status, diabetes, steroid use), prior breast cancer treatment, drain duration, and antibiotic use was abstracted from medical records. Multivariable logistic regression was used to assess the association between postoperative antibiotic use and the occurrence of SSI, adjusting for concurrent risk factors. Results Among 480 patients undergoing mastectomy without reconstruction, 425 had sufficient documentation for analysis. Of these, 268 were prescribed antibiotics (63 %) at hospital discharge. An overall SSI rate of 7.3 % was observed, with 14 % of patients without postoperative antibiotics developing SSI compared with 3.4 % with antibiotics (p < 0.0001). Factors independently associated with SSI were smoking and advancing age. Diabetes, steroid use, BMI, prior breast surgery, neoadjuvant chemotherapy, prior radiation, concomitant axillary surgery, and drain duration were not associated with increased SSI rates. Conclusions SSI rates among patients who did and did not receive postoperative antibiotics after mastectomy were significantly different, particularly among smokers and women of advanced age. These patient subgroups may warrant special consideration for postoperative antibiotics. PMID:25138078

Measurements of the Solar Spectral Irradiance Variability over Solar Cycles 21 to 24

NASA Astrophysics Data System (ADS)

Woods, T. N.

2017-12-01

The solar irradiance is the primary natural energy input into Earth's atmosphere and climate system. Understanding the long-term variations of the solar spectral irradiance (SSI) over time scales of the 11-year solar activity cycle and longer is critical for most Sun-climate research topics. There are satellite measurements of the SSI since the 1970s that contribute to understanding the solar cycle variability over Solar Cycles 21 to 24. A limiting factor for the accuracy of these results is the uncertainties for the instrument degradation corrections, for which there are fairly large corrections relative to the amount of solar cycle variability at some wavelengths. A summary of these satellite SSI measurements, which are primarily in the ultraviolet and only recently in the visible and near infrared, will be presented. Examining SSI trends using a new analysis technique is helping to identify some uncorrected instrumental trends, which once applied to the SSI trends has the potential to provide more accurate solar cycle variability results. This new technique examines the SSI trends at different levels of solar activity to provide long-term trends in a SSI record, and one of the most common components of these derived long-term trends is a downward trend that we attribute to being most likely from uncorrected instrument degradation. Examples of this analysis will be presented for some of the satellite SSI measurements to demonstrate this new technique and how it has potential to improve the understanding of solar cycle variability and to clarify the uncertainties of the trends.

Reduction of Surgical Site Infections after Implementation of a Bundle of Care

PubMed Central

Crolla, Rogier M. P. H.; van der Laan, Lijckle; Veen, Eelco J.; Hendriks, Yvonne; van Schendel, Caroline; Kluytmans, Jan

2012-01-01

Background Surgical Site Infections (SSI) are relatively frequent complications after colorectal surgery and are associated with substantial morbidity and mortality. Objective Implementing a bundle of care and measuring the effects on the SSI rate. Design Prospective quasi experimental cohort study. Methods A prospective surveillance for SSI after colorectal surgery was performed in the Amphia Hospital, Breda, from January 1, 2008 until January 1, 2012. As part of a National patient safety initiative, a bundle of care consisting of 4 elements covering the surgical process was introduced in 2009. The elements of the bundle were perioperative antibiotic prophylaxis, hair removal before surgery, perioperative normothermia and discipline in the operating room. Bundle compliance was measured every 3 months in a random sample of surgical procedures. Results Bundle compliance improved significantly from an average of 10% in 2009 to 60% in 2011. 1537 colorectal procedures were performed during the study period and 300 SSI (19.5%) occurred. SSI were associated with a prolonged length of stay (mean additional length of stay 18 days) and a significantly higher 6 months mortality (Adjusted OR: 2.71, 95% confidence interval 1.76–4.18). Logistic regression showed a significant decrease of the SSI rate that paralleled the introduction of the bundle. The adjusted Odds ratio of the SSI rate was 36% lower in 2011 compared to 2008. Conclusion The implementation of the bundle was associated with improved compliance over time and a 36% reduction of the SSI rate after adjustment for confounders. This makes the bundle an important tool to improve patient safety. PMID:22962619

Russian Elite Image of Iran: From the Late Soviet Era to the Present

DTIC Science & Technology

2009-09-01

Government. Authors of Strategic Studies Institute (SSI) publications enjoy full academic freedom, provided they do not disclose classified...information, jeopardize operations security, or misrepresent official U.S. policy. Such academic freedom empowers them to offer new and sometimes...publications, but in respectable academic journals and influential publishing houses. Above all, it could be seen in Dugin’s position. From a staunch

McIDAS-eXplorer: A version of McIDAS for planetary applications

NASA Technical Reports Server (NTRS)

Limaye, Sanjay S.; Saunders, R. Stephen; Sromovsky, Lawrence A.; Martin, Michael

1994-01-01

McIDAS-eXplorer is a set of software tools developed for analysis of planetary data published by the Planetary Data System on CD-ROM's. It is built upon McIDAS-X, an environment which has been in use nearly two decades now for earth weather satellite data applications in research and routine operations. The environment allows convenient access, navigation, analysis, display, and animation of planetary data by utilizing the full calibration data accompanying the planetary data. Support currently exists for Voyager images of the giant planets and their satellites; Magellan radar images (F-MIDR and C-MIDR's, global map products (GxDR's), and altimetry data (ARCDR's)); Galileo SSI images of the earth, moon, and Venus; Viking Mars images and MDIM's as well as most earth based telescopic images of solar system objects (FITS). The NAIF/JPL SPICE kernels are used for image navigation when available. For data without the SPICE kernels (such as the bulk of the Voyager Jupiter and Saturn imagery and Pioneer Orbiter images of Venus), tools based on NAIF toolkit allow the user to navigate the images interactively. Multiple navigation types can be attached to a given image (e.g., for ring navigation and planet navigation in the same image). Tools are available to perform common image processing tasks such as digital filtering, cartographic mapping, map overlays, and data extraction. It is also possible to have different planetary radii for an object such as Venus which requires a different radius for the surface and for the cloud level. A graphical user interface based on Tel-Tk scripting language is provided (UNIX only at present) for using the environment and also to provide on-line help. It is possible for end users to add applications of their own to the environment at any time.

Noninvasive characterization of carotid plaque strain.

PubMed

Khan, Amir A; Sikdar, Siddhartha; Hatsukami, Thomas; Cebral, Juan; Jones, Michael; Huston, John; Howard, George; Lal, Brajesh K

2017-06-01

Current risk stratification of internal carotid artery plaques based on diameter-reducing percentage stenosis may be unreliable because ischemic stroke results from plaque disruption with atheroembolization. Biomechanical forces acting on the plaque may render it vulnerable to rupture. The feasibility of ultrasound-based quantification of plaque displacement and strain induced by hemodynamic forces and their relationship to high-risk plaques have not been determined. We studied the feasibility and reliability of carotid plaque strain measurement from clinical B-mode ultrasound images and the relationship of strain to high-risk plaque morphology. We analyzed carotid ultrasound B-mode cine loops obtained in patients with asymptomatic ≥50% stenosis during routine clinical scanning. Optical flow methods were used to quantify plaque motion and shear strain during the cardiac cycle. The magnitude (maximum absolute shear strain rate [MASSR]) and variability (entropy of shear strain rate [ESSR] and variance of shear strain rate [VSSR]) of strain were combined into a composite shear strain index (SSI), which was assessed for interscan repeatability and correlated with plaque echolucency. Nineteen patients (mean age, 70 years) constituting 36 plaques underwent imaging; 37% of patients (n = 7) showed high strain (SSI ≥0.5; MASSR, 2.2; ESSR, 39.7; VSSR, 0.03) in their plaques; the remaining clustered into a low-strain group (SSI <0.5; MASSR, 0.58; ESSR, 21.2; VSSR, 0.002). The area of echolucent morphology was greater in high-strain plaques vs low-strain plaques (28% vs 17%; P = .018). Strain measurements showed low variability on Bland-Altman plots with cluster assignment agreement of 76% on repeated scanning. Two patients developed a stroke during 2 years of follow-up; both demonstrated high SSI (≥0.5) at baseline. Carotid plaque strain is reliably computed from routine B-mode imaging using clinical ultrasound machines. High plaque strain correlates with known high-risk echolucent morphology. Strain measurement can complement identification of patients at high risk for plaque disruption and stroke. Copyright © 2017 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.

40 CFR 60.5130 - What are the operator training and qualification requirements?

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emission Guidelines... operated unless a fully trained and qualified SSI unit operator is accessible, either at the facility or can be at the facility within 1 hour. The trained and qualified SSI unit operator may operate the SSI...

40 CFR 60.4810 - What are the operator training and qualification requirements?

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Standards of... the operator training and qualification requirements? (a) A SSI unit cannot be operated unless a fully... within 1 hour. The trained and qualified SSI unit operator may operate the SSI unit directly or be the...

40 CFR 60.4810 - What are the operator training and qualification requirements?

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Standards of... the operator training and qualification requirements? (a) A SSI unit cannot be operated unless a fully... within 1 hour. The trained and qualified SSI unit operator may operate the SSI unit directly or be the...

40 CFR 60.5130 - What are the operator training and qualification requirements?

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emission Guidelines... operated unless a fully trained and qualified SSI unit operator is accessible, either at the facility or can be at the facility within 1 hour. The trained and qualified SSI unit operator may operate the SSI...

40 CFR 60.4810 - What are the operator training and qualification requirements?

Code of Federal Regulations, 2012 CFR

2012-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Standards of... the operator training and qualification requirements? (a) A SSI unit cannot be operated unless a fully... within 1 hour. The trained and qualified SSI unit operator may operate the SSI unit directly or be the...

20 CFR 408.425 - How do we establish your eligibility for SSI?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false How do we establish your eligibility for SSI? 408.425 Section 408.425 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SPECIAL BENEFITS FOR CERTAIN WORLD WAR II VETERANS Evidence Requirements Ssi Eligibility § 408.425 How do we establish your...

20 CFR 408.425 - How do we establish your eligibility for SSI?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false How do we establish your eligibility for SSI? 408.425 Section 408.425 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SPECIAL BENEFITS FOR CERTAIN WORLD WAR II VETERANS Evidence Requirements Ssi Eligibility § 408.425 How do we establish your...

20 CFR 408.425 - How do we establish your eligibility for SSI?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false How do we establish your eligibility for SSI? 408.425 Section 408.425 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SPECIAL BENEFITS FOR CERTAIN WORLD WAR II VETERANS Evidence Requirements Ssi Eligibility § 408.425 How do we establish your...

20 CFR 408.425 - How do we establish your eligibility for SSI?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false How do we establish your eligibility for SSI? 408.425 Section 408.425 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SPECIAL BENEFITS FOR CERTAIN WORLD WAR II VETERANS Evidence Requirements Ssi Eligibility § 408.425 How do we establish your...

20 CFR 408.425 - How do we establish your eligibility for SSI?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false How do we establish your eligibility for SSI? 408.425 Section 408.425 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SPECIAL BENEFITS FOR CERTAIN WORLD WAR II VETERANS Evidence Requirements Ssi Eligibility § 408.425 How do we establish your...

SSI Variations in the visible as observed with SOLAR/SOLSPEC during cycle 24 - Comparison with SORCE/SIM.

NASA Astrophysics Data System (ADS)

Irbah, A.; Damé, L.; Meftah, M.; Bekki, S.; Bolsée, D.

2017-12-01

The solar spectral irradiance (SSI) and its temporal variations are of prime importance to apprehend the physics of the Sun and to understand its effects on Earth climate through changes of atmospheric properties. Ground based measurements of SSI are indeed affected by the Earth atmosphere and space observations are therefore required to perform adequate observations. Only a few long series of SSI space measurements were obtained these last decades. The SOLSPEC instrument of the SOLAR payload on the International Space Station (ISS) has recorded one of them from April 2008 to February 2017 covering almost the whole solar cycle 24. The instrument is a spectro-radiometer recording data of the Sun from 166 to 3088 nm. Operated from the ISS in a harsh environment it needed appropriate processing methods to extract significant scientific results from noise and instrumental effects. We present the methods used to process the data to evidence visible SSI variations during cycle 24. We discuss the results obtained showing SSI variations in phase with solar activity. We compare them with SORCE/SIM measurements.

Climate variability related to the 11 year solar cycle as represented in different spectral solar irradiance reconstructions

NASA Astrophysics Data System (ADS)

Kruschke, Tim; Kunze, Markus; Misios, Stergios; Matthes, Katja; Langematz, Ulrike; Tourpali, Kleareti

2016-04-01

Advanced spectral solar irradiance (SSI) reconstructions differ significantly from each other in terms of the mean solar spectrum, that is the spectral distribution of energy, and solar cycle variability. Largest uncertainties - relative to mean irradiance - are found for the ultraviolet range of the spectrum, a spectral region highly important for radiative heating and chemistry in the stratosphere and troposphere. This study systematically analyzes the effects of employing different SSI reconstructions in long-term (40 years) chemistry-climate model (CCM) simulations to estimate related uncertainties of the atmospheric response. These analyses are highly relevant for the next round of CCM studies as well as climate models within the CMIP6 exercise. The simulations are conducted by means of two state-of-the-art CCMs - CESM1(WACCM) and EMAC - run in "atmosphere-only"-mode. These models are quite different with respect to the complexity of the implemented radiation and chemistry schemes. CESM1(WACCM) features a chemistry module with considerably higher spectral resolution of the photolysis scheme while EMAC employs a radiation code with notably higher spectral resolution. For all simulations, concentrations of greenhouse gases and ozone depleting substances, as well as observed sea surface temperatures (SST) are set to average conditions representative for the year 2000 (for SSTs: mean of decade centered over year 2000) to exclude anthropogenic influences and differences due to variable SST forcing. Only the SSI forcing differs for the various simulations. Four different forcing datasets are used: NRLSSI1 (used as a reference in all previous climate modeling intercomparisons, i.e. CMIP5, CCMVal, CCMI), NRLSSI2, SATIRE-S, and the SSI forcing dataset recommended for the CMIP6 exercise. For each dataset, a solar maximum and minimum timeslice is integrated, respectively. The results of these simulations - eight in total - are compared to each other with respect to their shortwave heating rate differences (additionally collated with line-by-line calculations using libradtran), differences in the photolysis rates, as well as atmospheric circulation features (temperature, zonal wind, geopotential height, etc.). It is shown that atmospheric responses to the different SSI datasets differ significantly from each other. This is a result from direct radiative effects as well as indirect effects induced by ozone feedbacks. Differences originating from using different SSI datasets for the same level of solar activity are in the same order of magnitude as those associated with the 11 year solar cycle within a specific dataset. However, the climate signals related to the solar cycle are quite comparable across datasets.

Middle Atmosphere Response to Different Descriptions of the 11-Year Solar Cycle in Spectral Irradiance in a Chemistry-Climate Model

NASA Technical Reports Server (NTRS)

Swartz, W. H.; Stolarski, R. S.; Oman, L. D.; Fleming, E. L.; Jackman, C. H.

2012-01-01

The 11-year solar cycle in solar spectral irradiance (SSI) inferred from measurements by the SOlar Radiation & Climate Experiment (SORCE) suggests a much larger variation in the ultraviolet than previously accepted. We present middle atmosphere ozone and temperature responses to the solar cycles in SORCE SSI and the ubiquitous Naval Research Laboratory (NRL) SSI reconstruction using the Goddard Earth Observing System chemistry-climate model (GEOS CCM). The results are largely consistent with other recent modeling studies. The modeled ozone response is positive throughout the stratosphere and lower mesosphere using the NRL SSI, while the SORCE SSI produces a response that is larger in the lower stratosphere but out of phase with respect to total solar irradiance above 45 km. The modeled responses in total ozone are similar to those derived from satellite and ground-based measurements, 3-6 Dobson Units per 100 units of 10.7-cm radio flux (F10.7) in the tropics. The peak zonal mean tropical temperature response 50 using the SORCE SSI is nearly 2 K per 100 units 3 times larger than the simulation using the NRL SSI. The GEOS CCM and the Goddard Space Flight Center (GSFC) 2-D coupled model are used to examine how the SSI solar cycle affects the atmosphere through direct solar heating and photolysis processes individually. Middle atmosphere ozone is affected almost entirely through photolysis, whereas the solar cycle in temperature is caused both through direct heating and photolysis feedbacks, processes that are mostly linearly separable. Further, the net ozone response results from the balance of ozone production at wavelengths less than 242 nm and destruction at longer wavelengths, coincidentally corresponding to the wavelength regimes of the SOLar STellar Irradiance Comparison Experiment (SOLSTICE) and Spectral Irradiance Monitor (SIM) on SORCE, respectively. A higher wavelength-resolution analysis of the spectral response could allow for a better prediction of the atmospheric response to arbitrary SSI variations.

Medical comorbidities and perioperative allogeneic red blood cell transfusion are risk factors for surgical site infection after shoulder arthroplasty.

PubMed

Everhart, Joshua S; Bishop, Julie Y; Barlow, Jonathan D

2017-11-01

Multiple perioperative factors have been implicated in infection risk after shoulder arthroplasty. The purpose of this study was to determine surgical site infection (SSI) risk due to medical comorbidities or blood transfusion after primary or revision shoulder arthroplasty. Comprehensive data on medical comorbidities, surgical indication, perioperative transfusion, and SSI were obtained for 707 patients who underwent primary or revision hemiarthroplasty or total shoulder arthroplasty in a single hospital system. Multivariate Poisson regression was used to determine the independent association between allogeneic red blood cell transfusion, medical comorbidities, and SSI after controlling for procedure. The SSI rate was 1.9% for primary hemiarthroplasties and 1.3% for primary total shoulder arthroplasties. Among patients without prior shoulder infection, revision arthroplasty or prior open reduction and internal fixation had higher SSI risk than primary arthroplasties (incidence risk ratio [IRR], 11.4; 95% confidence interval [CI], 3.84-34.0; P < .001); among primary arthroplasties, SSI risk factors included male gender (IRR, 60.0; CI, 4.39-819; P = .002), rheumatoid arthritis (IRR, 8.63; CI, 1.84-40.4; P = .006), and long-term corticosteroid use (IRR, 37.4; CI, 5.79-242; P < .001). Perioperative allogeneic red blood cell transfusion significantly increased SSI risk and was dose dependent (IRR, 1.68 per unit packed red blood cell; CI, 1.21-2.35; P = .002). Gender, rheumatoid arthritis, and long-term (>1 year) corticosteroid use affect SSI risk after shoulder arthroplasty. Revision surgery, particularly in the setting of prior infection, increased risk of future infection. Finally, allogeneic red blood cell transfusion increases SSI risk after shoulder arthroplasty in a dose-dependent manner. Copyright © 2017 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

A positive association between nutritional risk and the incidence of surgical site infections: A hospital-based register study.

PubMed

Skeie, Eli; Koch, Anne Mette; Harthug, Stig; Fosse, Unni; Sygnestveit, Kari; Nilsen, Roy Miodini; Tangvik, Randi J

2018-01-01

Surgical site infections (SSI) are amongst the most common health care-associated infections and have adverse effects for patient health and for hospital resources. Although surgery guidelines recognize poor nutritional status to be a risk factor for SSI, they do not tell how to identify this condition. The screening tool Nutritional Risk Screening 2002 is commonly used at hospitals to identify patients at nutritional risk. We investigated the association between nutritional risk and the incidence of SSI among 1194 surgical patients at Haukeland University Hospital (Bergen, Norway). This current study combines data from two mandatory hospital-based registers: a) the incidence of SSI within 30 days after surgery, and b) the point-prevalence of patients at nutritional risk. Patients with more than 30 days between surgery and nutritional risk screening were excluded. Associations were assessed using logistic regression, and the adjusted odds ratio included age (continuous), gender (male/female), type of surgery (acute/elective) and score from The American Society of Anesthesiologists Physical Status Classification System. There was a significant higher incidence of SSI among patients at nutritional risk (11.8%), as compared to those who were not (7.0%) (p = 0.047). Moreover, the incidence of SSI was positively associated with the prevalence of nutritional risk in both simple (OR 1.76 (95% CI: 1.04, 2.98)) and adjusted (OR 1.81 (95% CI: 1.04, 3.16)) models. Answering "yes" to the screening questions regarding reduced dietary intake and weight loss was significantly associated with the incidence of SSI (respectively OR 2.66 (95% CI: 1.59, 4.45) and OR 2.15 (95% CI: 1.23, 3.76)). In conclusion, we demonstrate SSI to occur more often among patients at nutritional risk as compared to those who are not at nutritional risk. Future studies should investigate interventions to prevent both SSI and nutritional risk among surgical patients.

Case Studies of Secondary School Teachers Designing Socioscientific Issues-Based Instruction and Their Students' Socioscientific Reasoning

NASA Astrophysics Data System (ADS)

Karahan, Engin

Addressing socioscientific issues (SSI) has been one of the main focuses in science education since the Science, Technology, and Society (STS) movement in the 1970s (Levinson, 2006); however, teaching controversial socioscientific issues has always been challenging for teachers (Dillon, 1994; Osborne, Duschl, & Fairbrother, 2002). Although teachers exhibit positive attitudes for using controversial socioscientific issues in their science classrooms, only a small percentage of them actually incorporate SSI content into their science curricula on a regular basis (Sadler, Amirshokoohi, Kazempour, & Allspaw, 2006; Lee & Witz, 2009). The literature in science education has highlighted the signi?cant relationships among teacher beliefs, teaching practices, and student learning (Bryan & Atwater, 2002; King, Shumow, & Lietz, 2001; Lederman, 1992). Despite the fact that the case studies present a relatively detailed picture of teachers' values and motivations for teaching SSI (e.g. Lee, 2006; Lee & Witz, 2009; Reis & Galvao, 2004), these studies still miss the practices of these teachers and potential outcomes for their students. Therefore, there is a great need for in-depth case studies that would focus on teachers' practices of designing and teaching SSI-based learning environments, their deeper beliefs and motivations for teaching SSI, and their students' response to these practices (Lee, 2006). This dissertation is structured as three separate, but related, studies about secondary school teachers' experiences of designing and teaching SSI-based classes and their students' understanding of science and SSI reasoning. The case studies in this dissertation seek answers for (1) teachers' practices of designing and teaching SSI-based instruction, as well as its relation to their deeper personal beliefs and motivations to teach SSI, and (2) how their students respond to their approaches of teaching SSI in terms of their science understanding and SSI reasoning. The first paper presents case studies of three secondary science teachers within three high schools located along the Minnesota River Basin. The findings of this study documented the experiences of the participant teachers, as well as the contextual influences on those experiences. The second paper presents a case study of a science teacher and a social studies teacher which describes how these two teachers collaboratively designed and taught an environmental ethics class. The results of this study documented teachers' ways of sharing responsibilities, bringing their content and pedagogical expertise, and promoting the agency of their students in the environmental ethics class. The final paper in this dissertation presents case studies of secondary school students who were the participants in the SSI-based science classes described in the first two studies. The results of this study provided evidence for participant students' understanding of science and their socioscientific reasoning, as well as how they were influenced by the instructional decisions their teachers made.

The different mechanisms of sporophytic self-incompatibility.

PubMed

Hiscock, Simon J; Tabah, David A

2003-06-29

Flowering plants have evolved a multitude of mechanisms to avoid self-fertilization and promote outbreeding. Self-incompatibility (SI) is by far the most common of these, and is found in ca. 60% of flowering plants. SI is a genetically controlled pollen-pistil recognition system that provides a barrier to fertilization by self and self-related pollen in hermaphrodite (usually co-sexual) flowering plants. Two genetically distinct forms of SI can be recognized: gametophytic SI (GSI) and sporophytic SI (SSI), distinguished by how the incompatibility phenotype of the pollen is determined. GSI appears to be the most common mode of SI and can operate through at least three different mechanisms, two of which have been characterized extensively at a molecular level in the Solanaceae and Papaveraceae. Because molecular studies of SSI have been largely confined to species from the Brassicaceae, predominantly Brassica species, it is not yet known whether SSI, like GSI, can operate through different molecular mechanisms. Molecular studies of SSI are now being carried out on Ipomoea trifida (Convolvulaceae) and Senecio squalidus (Asteraceae) and are providing important preliminary data suggesting that SSI in these two families does not share the same molecular mechanism as that of the Brassicaceae. Here, what is currently known about the molecular regulation of SSI in the Brassicaceae is briefly reviewed, and the emerging data on SSI in I. trifida, and more especially in S. squalidus, are discussed.

Simulation of boreal Summer Monsoon Rainfall using CFSV2_SSiB model: sensitivity to Land Use Land Cover (LULC)

NASA Astrophysics Data System (ADS)

Chilukoti, N.; Xue, Y.

2016-12-01

The land surface play a vital role in determining the surface energy budget, accurate representation of land use and land cover (LULC) is necessary to improve forecast. In this study, we have investigated the influence of surface vegetation maps with different LULC on simulating the boreal summer monsoon rainfall. Using a National Centres for Environmental Prediction (NCEP) Coupled Forecast System version 2(CFSv2) model coupled with Simplified Simple Biosphere (SSiB) model, two experiments were conducted: one with old vegetation map and one with new vegetation map. The significant differences between new and old vegetation map were in semi-arid and arid areas. For example, in old map Tibetan plateau classified as desert, which is not appropriate, while in new map it was classified as grasslands or shrubs with bare soil. Old map classified the Sahara desert as a bare soil and shrubs with bare soil, whereas in new map it was classified as bare ground. In addition to central Asia and the Sahara desert, in new vegetation map, Europe had more cropped area and India's vegetation cover was changed from crops and forests to wooded grassland and small areas of grassland and shrubs. The simulated surface air temperature with new map shows a significant improvement over Asia, South Africa, and northern America by some 1 to 2ºC and 2 to 3ºC over north east China and these are consistent with the reduced rainfall biases over Africa, near Somali coast, north east India, Bangladesh, east China sea, eastern Pacific and northern USA. Over Indian continent and bay of Bengal dry rainfall anomalies that is the only area showing large dry rainfall bias, however, they were unchanged with new map simulation. Overall the CFSv2(coupled with SSiB) model with new vegetation map show a promising result in improving the monsoon forecast by improving the Land -Atmosphere interactions. To compare with the LULC forcing, experiment was conducted using the Global Forecast System (GFS) simulations forced with different observed Sea Surface Temperatures (SST) for the same period: one is from NCEP reanalysis and one from Hadley Center. They have substantial difference in Indian Ocean. Preliminary analysis shows that, the impact of these two SST data sets on Indian summer monsoon rainfall has no significant impact.

Designing and Implementing Web-Based Scaffolding Tools for Technology-Enhanced Socioscientific Inquiry

ERIC Educational Resources Information Center

Shin, Suhkyung; Brush, Thomas A.; Glazewski, Krista D.

2017-01-01

This study explores how web-based scaffolding tools provide instructional support while implementing a socio-scientific inquiry (SSI) unit in a science classroom. This case study focused on how students used web-based scaffolding tools during SSI activities, and how students perceived the SSI unit and the scaffolding tools embedded in the SSI…

High-Resolution Topography and its Implications for the Formation of Europa's Ridged Plains

NASA Astrophysics Data System (ADS)

Leonard, E. J.; Pappalardo, R. T.; Yin, A.; Patthoff, D. A.; Schenk, P.

2015-12-01

The Galileo Solid State Imager (SSI) recorded nine very high-resolution frames—eight at 12 m/pixel and one at 6 m/pixel—during the E12 flyby of Europa in Dec. 1997. To understand the implications for the small-scale structure and evolution of Europa, we mosaicked these frames (observations 12ESMOTTLE01 and 02, incidence ≈18°, emission ≈77°) into their regional context (part of observation 11ESREGMAP01, 220 m/pixel, incidence ≈74°, emission ≈23°). The topography data, which was created from the image mosaic overlaps, is sparse and segmented over the high-resolution images but connected by the underlying regional resolution topography. The high-resolution topography (24 m/pixel) is among the best for the current Europan dataset. From this dataset we ascertain the root mean square, or RMS, slope for some of the most common Europan surface features in a new region. We also employ a Fourier Transform method previously used on Ganymede and on other areas of Europa (Patel et al., 1999 JGR), to derive common wavelengths for the subunits of the ubiquitous ridged plains terrain. These results have important implications for differentiating between possible formation mechanisms—extensional tilt blocks (Pappalardo et al., 1995 JGR) or folds (Leonard et al., 2015 LPSC Abstract)—and for potential future missions. We continue this method for another high-resolution region taken in the E12 orbit, WEDGES01 and 02, with the specific goal of investigating how the variations in ridged plains morphologies relate across the surface of Europa.

Demonstrating success in reducing adult cardiac surgical site infections and the economic impact of using multidisciplinary collaboration.

PubMed

Chiwera, Lilian; Wigglesworth, Neil; McCoskery, Carol; Lucchese, Gianluca; Newsholme, William

2018-03-28

Cardiac surgical site infections (SSIs) have devastating consequences and present several challenges for patients and healthcare providers. Adult cardiac SSI surveillance commenced in 2009 at our hospitals, Guy's & St Thomas' NHS Foundation Trust, London, as a patient safety initiative amid reported increased incidence of SSIs. Before this time, infection incidence was unclear because data collection was not standardised. Our aim was to standardise SSI data collection and establish baseline SSI rates to facilitate deployment of evidence based targeted interventions within clinical governance structures to improve quality, safety and efficiency in line with our organisational targets. We standardised local data collection protocols in line with Public Health England recommendations and identified local champions. We undertook prospective SSI surveillance collaboratively to enable us to identify potential practice concerns and address them more effectively through a series of initiatives. Clinical staff completed dedicated surveillance forms intraoperatively and post operatively. Overall adult cardiac SSI rates fell from 5.4% in 2009 to 1.2% in 2016 and Coronary Artery Bypass Graft (CABG) rates from 6.5% in 2009 to 1.7% in 2016, p<0.001. Gram negative bacteria were recognised as important SSI causative organisms and were better controlled after introducing stringent infection control measures. We successfully implemented comprehensive, evidence-based infection control practices through a multidisciplinary collaborative approach; an approach we consider to have great potential to reduce Gram negative, Staphylococcus aureus, polymicrobial and overall SSI burden and/or associated costs. We now investigate all SSIs using an established SSI detailed investigation protocol to promote continual quality improvement that aligns us perfectly with global efforts to fight antimicrobial resistance. Copyright © 2018. Published by Elsevier Ltd.

Surgical site infections following craniotomy focusing on possible post-operative acquisition of infection: prospective cohort study.

PubMed

Sneh-Arbib, O; Shiferstein, A; Dagan, N; Fein, S; Telem, L; Muchtar, E; Eliakim-Raz, N; Rubinovitch, B; Rubin, G; Rappaport, Z H; Paul, M

2013-12-01

Neurosurgery is characterized by a prolonged risk period for surgical site infection (SSI), mainly related to the presence of cerebrospinal fluid (CSF) drains. We aimed to examine factors associated with post-neurosurgical SSIs, focusing on post-operative factors. A prospective cohort study was conducted in a single center over a period of 18 months in Israel. Included were adult patients undergoing clean or clean-contaminated craniotomy, including craniotomies with external CSF drainage or shunts. SSIs were defined by the Centers for Disease Control and Prevention (CDC) criteria for healthcare-associated infections. All patients were followed up for 90 days and those with foreign body insertion for 1 year. We compared patients with and without SSI. A multivariable regression analysis for SSI was conducted including uncorrelated variables significantly associated with SSI. A total of 502 patients were included, with 138 (27.5%) undergoing emergent or urgent craniotomy. The overall SSI rate was 5.6% (28 patients), of which 3.2% (16 patients) were intracerebral. Non-elective surgery, external CSF drainage/monitoring devices, re-operation, and post-operative respiratory failure were independently associated with subsequent SSI. External CSF devices was the only significant risk factor for intracerebral SSIs (p < 0.001). Internal shunts or other foreign body insertions were not associated with SSIs. A phenotypically identical isolate to that causing the SSI was isolated from respiratory secretions prior to the SSI in 4/9 patients with microbiologically documented intracerebral SSIs. Patients with SSIs had longer hospital stay, poorer functional capacity on discharge, and higher 90-day mortality. We raise the possibility of post-operative infection acquisition through external CSF devices. Standard operating procedures for their maintenance are necessary.

Secondary School Students' Understanding of Science and Their Socioscientific Reasoning

NASA Astrophysics Data System (ADS)

Karahan, Engin; Roehrig, Gillian

2017-08-01

Research in socioscientific issue (SSI)-based interventions is relatively new (Sadler in Journal of Research in Science Teaching 41:513-536, 2004; Zeidler et al. in Journal of Research in Science Teaching 46:74-101, 2009), and there is a need for understanding more about the effects of SSI-based learning environments (Sadler in Journal of Research in Science Teaching 41:513-536, 2004). Lee and Witz (International Journal of Science Education 31:931-960, 2009) highlighted the need for detailed case studies that would focus on how students respond to teachers' practices of teaching SSI. This study presents case studies that investigated the development of secondary school students' science understanding and their socioscientific reasoning within SSI-based learning environments. A multiple case study with embedded units of analysis was implemented for this research because of the contextual differences for each case. The findings of the study revealed that students' understanding of science, including scientific method, social and cultural influences on science, and scientific bias, was strongly influenced by their experiences in SSI-based learning environments. Furthermore, multidimensional SSI-based science classes resulted in students having multiple reasoning modes, such as ethical and economic reasoning, compared to data-driven SSI-based science classes. In addition to portraying how participants presented complexity, perspectives, inquiry, and skepticism as aspects of socioscientific reasoning (Sadler et al. in Research in Science Education 37:371-391, 2007), this study proposes the inclusion of three additional aspects for the socioscientific reasoning theoretical construct: (1) identification of social domains affecting the SSI, (2) using cost and benefit analysis for evaluation of claims, and (3) understanding that SSIs and scientific studies around them are context-bound.

Independent risk factors for surgical site infection after cesarean delivery in a rural tertiary care medical center.

PubMed

Vallejo, Manuel C; Attaallah, Ahmed F; Shapiro, Robert E; Elzamzamy, Osama M; Mueller, Michael G; Eller, Warren S

2017-02-01

We aimed to determine the incidence of surgical site infection (SSI) after cesarean delivery (CD) and identify the risk factors in a rural population. We identified 218 SSI patients by International Classification of Disease codes and matched them with 3131 parturients (control) from the electronic record database in a time-matched retrospective quality assurance analysis. The incidence of SSI after CD was 7.0 %. Risk factors included higher body mass index (BMI) [40.30 ± 10.60 kg/m 2 SSI (95 % CI 38.73-41.87) vs 34.05 ± 8.24 kg/m 2 control (95 % CI 33.75-34.35, P < 0.001)], years of education [13.28 ± 2.44 years SSI (95 % CI 12.9-13.66) vs 14.07 ± 2.81 years control (95 % CI 13.96-14.18, P < 0.001)], number of prior births [2 (1-9) SSI vs 1 (1-11) control (P < 0.001)], tobacco use (OR 1.49; 95 % CI 1.06-2.09, P = 0.03), prior diagnosis of hypertension (OR 1.80; 95 % CI 1.34-2.42, P < 0.001), gestational diabetes (OR 1.59; 95 % CI 1.18-2.13, P = 0.003), and an emergency/STAT CD (OR 1.6; 95 % CI 1.1-2.3, P = 0.01). Risk factors for SSI after CD included higher BMI, less years of education, higher prior births, tobacco use, prior diagnosis of hypertension, gestational diabetes, and emergency/STAT CD. The presence of ruptured membranes was protective against SSI.

Multi-equilibrium property of metabolic networks: SSI module.

PubMed

Lei, Hong-Bo; Zhang, Ji-Feng; Chen, Luonan

2011-06-20

Revealing the multi-equilibrium property of a metabolic network is a fundamental and important topic in systems biology. Due to the complexity of the metabolic network, it is generally a difficult task to study the problem as a whole from both analytical and numerical viewpoint. On the other hand, the structure-oriented modularization idea is a good choice to overcome such a difficulty, i.e. decomposing the network into several basic building blocks and then studying the whole network through investigating the dynamical characteristics of the basic building blocks and their interactions. Single substrate and single product with inhibition (SSI) metabolic module is one type of the basic building blocks of metabolic networks, and its multi-equilibrium property has important influence on that of the whole metabolic networks. In this paper, we describe what the SSI metabolic module is, characterize the rates of the metabolic reactions by Hill kinetics and give a unified model for SSI modules by using a set of nonlinear ordinary differential equations with multi-variables. Specifically, a sufficient and necessary condition is first given to describe the injectivity of a class of nonlinear systems, and then, the sufficient condition is used to study the multi-equilibrium property of SSI modules. As a main theoretical result, for the SSI modules in which each reaction has no more than one inhibitor, a sufficient condition is derived to rule out multiple equilibria, i.e. the Jacobian matrix of its rate function is nonsingular everywhere. In summary, we describe SSI modules and give a general modeling framework based on Hill kinetics, and provide a sufficient condition for ruling out multiple equilibria of a key type of SSI module.

Multi-equilibrium property of metabolic networks: SSI module

PubMed Central

2011-01-01

Background Revealing the multi-equilibrium property of a metabolic network is a fundamental and important topic in systems biology. Due to the complexity of the metabolic network, it is generally a difficult task to study the problem as a whole from both analytical and numerical viewpoint. On the other hand, the structure-oriented modularization idea is a good choice to overcome such a difficulty, i.e. decomposing the network into several basic building blocks and then studying the whole network through investigating the dynamical characteristics of the basic building blocks and their interactions. Single substrate and single product with inhibition (SSI) metabolic module is one type of the basic building blocks of metabolic networks, and its multi-equilibrium property has important influence on that of the whole metabolic networks. Results In this paper, we describe what the SSI metabolic module is, characterize the rates of the metabolic reactions by Hill kinetics and give a unified model for SSI modules by using a set of nonlinear ordinary differential equations with multi-variables. Specifically, a sufficient and necessary condition is first given to describe the injectivity of a class of nonlinear systems, and then, the sufficient condition is used to study the multi-equilibrium property of SSI modules. As a main theoretical result, for the SSI modules in which each reaction has no more than one inhibitor, a sufficient condition is derived to rule out multiple equilibria, i.e. the Jacobian matrix of its rate function is nonsingular everywhere. Conclusions In summary, we describe SSI modules and give a general modeling framework based on Hill kinetics, and provide a sufficient condition for ruling out multiple equilibria of a key type of SSI module. PMID:21689474

Sternocleidomastoid muscle flap used for repairing the dead space after supraomohyoid neck dissection

PubMed Central

Li, Jinzhong; Han, Zhengxue

2015-01-01

Surgical site infection (SSI) is a common complication followed neck dissection and dead space is a common reason of SSI. The present study is aimed to explore whether the sternocleidomastoid muscle (SCM) flap transposition to repair the dead space in level II of neck could decrease the postoperative SSI in patients with oral squamous cell carcinoma (OSCC) underwent supraomohyoid neck dissection (SOND). Ninety-six patients with cT2-3N0 OSCC who underwent extended resection of primary cancer combined SOND and reconstructed with free flap from March 2011 to October 2014 in our department were included. Forty-eight cases underwent SCM transposition to repair the potential dead space in level II of the neck, the other 48 cases did not. The two groups were matched at age, gender, concomitant diseases, and perioperative treatments. All the patients underwent exhaustive hemostasis and careful placement of negative pressure drainage. The wound healing was observed on 7 days postoperatively. The SSI rates of neck between the two groups were compared using Fisher’s exact test. The dead space in level II was observed in all the neck wounds after SOND. The neck wounds healed by primary intention in 46 cases underwent SCM flap transposition, and in 39 cases underwent routine SOND only. Two cases with SCM flap transposition and 9 cases in the group without SCM flap transposition presented SSI in neck. There was significant difference in the SSI rate between the two groups (P = 0.0248). The dead space in level II could be an important cause of SSI in neck followed SOND. Repairing of the dead space in level II using SCM flap transposition reduce the SSI rate of neck followed SOND. PMID:25785129

Efficacy of triclosan-coated sutures for reducing risk of surgical site infection in adults: a meta-analysis of randomized clinical trials.

PubMed

Guo, Jiao; Pan, Ling-Hui; Li, Yun-Xi; Yang, Xiang-Di; Li, Le-Qun; Zhang, Chun-Yan; Zhong, Jian-Hong

2016-03-01

Surgical site infection (SSI) is the third most frequent type of nosocomial infections. Triclosan-coated sutures are often used to reduce the risk of SSI, but studies examining this have given conflicting results. Therefore, this meta-analysis was performed to assess the efficacy of triclosan-coated sutures for reducing risk of SSI in adults. PubMed, EMBASE, Google Scholar, and ClinicalTrials.gov were searched to identify randomized clinical trials evaluating triclosan-coated sutures for preventing SSI on patients 18 y or older. Thirteen randomized clinical trials involving 5256 participants were included. Triclosan-coated sutures were associated with lower risk of SSI than uncoated sutures across all surgeries (risk ratio [RR] 0.76, 95% confidence interval [CI] 0.65-0.88, P < 0.001). Similar proportions of patients experienced wound dehiscence with either type of suture (RR 0.97, 95% CI 0.49-1.89, P = 0.92). Subgroup analysis showed lower risk of SSI with triclosan-coated sutures in abdominal surgeries (RR 0.70, 95% CI 0.50-0.99, P = 0.04) and group with prophylactic antibiotic (RR 0.79, 95% CI 0.63-0.99, P = 0.04). However, such risk reduction was not observed in cardiac surgeries, breast surgeries, or group without prophylactic antibiotic. Triclosan-coated sutures can decrease the incidence of SSI in abdominal surgeries and might not interfere with wound healing process. Nevertheless, further studies are needed to examine whether triclosan-coated sutures are effective at preventing SSI in non-abdominal surgeries and to further study the interaction of antibiotic prophylaxis with triclosan-coated sutures. Copyright © 2016 Elsevier Inc. All rights reserved.

Sternocleidomastoid muscle flap used for repairing the dead space after supraomohyoid neck dissection.

PubMed

Li, Jinzhong; Han, Zhengxue

2015-01-01

Surgical site infection (SSI) is a common complication followed neck dissection and dead space is a common reason of SSI. The present study is aimed to explore whether the sternocleidomastoid muscle (SCM) flap transposition to repair the dead space in level II of neck could decrease the postoperative SSI in patients with oral squamous cell carcinoma (OSCC) underwent supraomohyoid neck dissection (SOND). Ninety-six patients with cT2-3N0 OSCC who underwent extended resection of primary cancer combined SOND and reconstructed with free flap from March 2011 to October 2014 in our department were included. Forty-eight cases underwent SCM transposition to repair the potential dead space in level II of the neck, the other 48 cases did not. The two groups were matched at age, gender, concomitant diseases, and perioperative treatments. All the patients underwent exhaustive hemostasis and careful placement of negative pressure drainage. The wound healing was observed on 7 days postoperatively. The SSI rates of neck between the two groups were compared using Fisher's exact test. The dead space in level II was observed in all the neck wounds after SOND. The neck wounds healed by primary intention in 46 cases underwent SCM flap transposition, and in 39 cases underwent routine SOND only. Two cases with SCM flap transposition and 9 cases in the group without SCM flap transposition presented SSI in neck. There was significant difference in the SSI rate between the two groups (P = 0.0248). The dead space in level II could be an important cause of SSI in neck followed SOND. Repairing of the dead space in level II using SCM flap transposition reduce the SSI rate of neck followed SOND.

Analysis of Dust Devils on Mars using CFD

NASA Astrophysics Data System (ADS)

Lange, C. F.; Chen, K.; Davis, J. A.; Gheynani, B. T.

2009-05-01

Recent Mars missions have reported evidence of the existence of dust devils. A detailed study of vortex dynamics will provide a better understanding of this swirling flow of the Martian atmosphere. Further, it is believed that there is a relationship between dust devils and water transport. Recently, the Phoenix Mars mission, designed to investigate ice water and natural events on Mars, has successfully finished. The Phoenix Surface Stereo Imager (SSI) camera captured images of the passage of dust devils over or close to the lander. Additionally, dustless devils, which have similar vortex characteristics but insufficient strength to raise dust from the surface, have been detected in the lander's pressure measurements. It was found that dust devils occur mainly in the early afternoon. Because of this, numerical models of a vortex generator are used to study the physics of this complex swirling flow and the effect of dust devils on the transport of water vapour from the regolith. Characteristic parameters such as core radius and swirl ratio are being explored for scaling factors. Scaling factors will be studied and tested, comparing the small and large scales of numerically generated vortices and laboratory generated vortices. Small scale of numerical models of atmospheric vortices are studied using a commercial software package, ANSYS/CFX11.0 with finite volume method (FVM). Large eddy simulations (LES) of planetary boundary layers are based on NCAR LES code to simulate convective vertical vortices that naturally form in quiescent convective boundary layers (CBL) over homogeneous flat surfaces. This will help to find the approximate location and physical characteristics of the vortices on the surface. The numerical models of atmospheric vortices and the experimental vortex generator validations will help to define the water vapour cycle on Mars.

Youth transitioning out of foster care: an evaluation of a Supplemental Security Income policy change.

PubMed

King, Laura; Rukh-Kamaa, Aneer

2013-01-01

Youths with disabilities face numerous challenges when they transition to adulthood. Those who are aging out of foster care face the additional challenge of losing their foster care benefits, although some will be eligible for Supplemental Security Income (SSI) payments after foster care ceases. However, the time needed to process SSI applications exposes those youths to a potential gap in the receipt of benefits as they move between foster care and SSI. We evaluate the effects of a 2010 Social Security Administration policy change that allows such youths to apply for SSI payments 60 days earlier than the previous policy allowed. The change provides additional time for processing claims before the applicant ages out of the foster care system. We examine administrative records on SSI applications from before and after the policy change to determine if the change has decreased the gap between benefits for the target population.

[Patient readmission for surgical site infection: integrative review].

PubMed

Machado, Lilian; Turrini, Ruth N T; Siqueira, Ana L

2013-02-01

Surgical site infections (SSI) represent an inherent risk after surgical procedures associated both to the surgical procedure and to the patient clinical conditions. To analyze in an integrative review the studies related to patient readmission due to SSI. The review was carried out by LILACS, CINHAL, MEDLINE and COCHRANE databases and articles published from 1966 to 2010 were selected. It was analyzed 13 studies classified as transversal (7), cohort (4) and longitudinal (2). Few studies analyzed only the readmissions related to the SSI. Time to define the readmission ranged from 28 to 90 days after surgery and studies related to orthopedic procedures were more frequent. The ISS readmission rates were lower than 5%. The main aetiological agents isolated from ISS were Staphylococcus aureus and coagulase-negative staphylococci. Monitoring readmissions due to SSI could contribute to dimension the occurrence of ISS post-discharge, once about half of the SSI post-discharge was diagnosed at the readmission moment.

Risk factors for surgical site infection following nonshunt pediatric neurosurgery: a review of 9296 procedures from a national database and comparison with a single-center experience

PubMed Central

Sherrod, Brandon A.; Arynchyna, Anastasia A.; Johnston, James M.; Rozzelle, Curtis J.; Blount, Jeffrey P.; Oakes, W. Jerry; Rocque, Brandon G.

2017-01-01

Objective Surgical site infection (SSI) following CSF shunt operations has been well studied, yet risk factors for nonshunt pediatric neurosurgery are less well understood. The purpose of this study was to determine SSI rates and risk factors following nonshunt pediatric neurosurgery using a nationwide patient cohort and an institutional dataset specifically for better understanding SSI. Methods The authors reviewed the American College of Surgeons National Surgical Quality Improvement Program Pediatric (ACS NSQIP-P) database for the years 2012–2014, including all neurosurgical procedures performed on pediatric patients except CSF shunts and hematoma evacuations. SSI included deep (intracranial abscesses, meningitis, osteomyelitis, and ventriculitis) and superficial wound infections. The authors performed univariate analyses of SSI association with procedure, demographic, comorbidity, operative, and hospital variables, with subsequent multivariate logistic regression analysis to determine independent risk factors for SSI within 30 days of the index procedure. A similar analysis was performed using a detailed institutional infection database from Children’s Hospital of Alabama (COA). Results A total of 9296 nonshunt procedures were identified in NSQIP-P with an overall 30-day SSI rate of 2.7%. The 30-day SSI rate in the COA institutional database was similar (3.3% of 1103 procedures, p = 0.325). Postoperative time to SSI in NSQIP-P and COA was 14.6 ± 6.8 days and 14.8 ± 7.3 days, respectively (mean ± SD). Myelomeningocele (4.3% in NSQIP-P, 6.3% in COA), spine (3.5%, 4.9%), and epilepsy (3.4%, 3.1%) procedure categoriess had the highest SSI rates by procedure category in both NSQIP-P and COA. Independent SSI risk factors in NSQIP-P included postoperative pneumonia (OR 4.761, 95% CI 1.269–17.857, p = 0.021), immune disease/immunosuppressant use (OR 3.671, 95% CI 1.371–9.827, p = 0.010), cerebral palsy (OR 2.835, 95% CI 1.463–5.494, p = 0.002), emergency operation (OR 1.843, 95% CI 1.011–3.360, p = 0.046), spine procedures (OR 1.673, 95% CI 1.036–2.702, p = 0.035), acquired CNS abnormality (OR 1.620, 95% CI 1.085–2.420, p = 0.018), and female sex (OR 1.475, 95% CI 1.062–2.049, p = 0.021). The only COA factor independently associated with SSI in the COA database included clean-contaminated wound classification (OR 3.887, 95% CI 1.354–11.153, p = 0.012), with public insurance (OR 1.966, 95% CI 0.957–4.041, p = 0.066) and spine procedures (OR 1.982, 95% CI 0.955–4.114, p = 0.066) approaching significance. Both NSQIP-P and COA multivariate model C-statistics were > 0.7. Conclusions NSQIP-P SSI rates, but not risk factors, were similar to data from a single center. PMID:28186476

Building an Open-source Simulation Platform of Acoustic Radiation Force-based Breast Elastography

PubMed Central

Wang, Yu; Peng, Bo; Jiang, Jingfeng

2017-01-01

Ultrasound-based elastography including strain elastography (SE), acoustic radiation force Impulse (ARFI) imaging, point shear wave elastography (pSWE) and supersonic shear imaging (SSI) have been used to differentiate breast tumors among other clinical applications. The objective of this study is to extend a previously published virtual simulation platform built for ultrasound quasi-static breast elastography toward acoustic radiation force-based breast elastography. Consequently, the extended virtual breast elastography simulation platform can be used to validate image pixels with known underlying soft tissue properties (i.e. “ground truth”) in complex, heterogeneous media, enhancing confidence in elastographic image interpretations. The proposed virtual breast elastography system inherited four key components from the previously published virtual simulation platform: an ultrasound simulator (Field II), a mesh generator (Tetgen), a finite element solver (FEBio) and a visualization and data processing package (VTK). Using a simple message passing mechanism, functionalities have now been extended to acoustic radiation force-based elastography simulations. Examples involving three different numerical breast models with increasing complexity – one uniform model, one simple inclusion model and one virtual complex breast model derived from magnetic resonance imaging data, were used to demonstrate capabilities of this extended virtual platform. Overall, simulation results were compared with the published results. In the uniform model, the estimated shear wave speed (SWS) values were within 4% compared to the predetermined SWS values. In the simple inclusion and the complex breast models, SWS values of all hard inclusions in soft backgrounds were slightly underestimated, similar to what has been reported. The elastic contrast values and visual observation show that ARFI images have higher spatial resolution, while SSI images can provide higher inclusion-to-background contrast. In summary, our initial results were consistent with our expectations and what have been reported in the literature. The proposed (open-source) simulation platform can serve as a single gateway to perform many elastographic simulations in a transparent manner, thereby promoting collaborative developments. PMID:28075330

Building an open-source simulation platform of acoustic radiation force-based breast elastography

NASA Astrophysics Data System (ADS)

Wang, Yu; Peng, Bo; Jiang, Jingfeng

2017-03-01

Ultrasound-based elastography including strain elastography, acoustic radiation force impulse (ARFI) imaging, point shear wave elastography and supersonic shear imaging (SSI) have been used to differentiate breast tumors among other clinical applications. The objective of this study is to extend a previously published virtual simulation platform built for ultrasound quasi-static breast elastography toward acoustic radiation force-based breast elastography. Consequently, the extended virtual breast elastography simulation platform can be used to validate image pixels with known underlying soft tissue properties (i.e. ‘ground truth’) in complex, heterogeneous media, enhancing confidence in elastographic image interpretations. The proposed virtual breast elastography system inherited four key components from the previously published virtual simulation platform: an ultrasound simulator (Field II), a mesh generator (Tetgen), a finite element solver (FEBio) and a visualization and data processing package (VTK). Using a simple message passing mechanism, functionalities have now been extended to acoustic radiation force-based elastography simulations. Examples involving three different numerical breast models with increasing complexity—one uniform model, one simple inclusion model and one virtual complex breast model derived from magnetic resonance imaging data, were used to demonstrate capabilities of this extended virtual platform. Overall, simulation results were compared with the published results. In the uniform model, the estimated shear wave speed (SWS) values were within 4% compared to the predetermined SWS values. In the simple inclusion and the complex breast models, SWS values of all hard inclusions in soft backgrounds were slightly underestimated, similar to what has been reported. The elastic contrast values and visual observation show that ARFI images have higher spatial resolution, while SSI images can provide higher inclusion-to-background contrast. In summary, our initial results were consistent with our expectations and what have been reported in the literature. The proposed (open-source) simulation platform can serve as a single gateway to perform many elastographic simulations in a transparent manner, thereby promoting collaborative developments.

Using Social Media to Promote Pre-Service Science Teachers' Practices of Socio-Scientific Issue (SSI) - Based Teaching

ERIC Educational Resources Information Center

Pitiporntapin, Sasithep; Lankford, Deanna Marie

2015-01-01

This paper addresses using social media to promote pre-service science teachers' practices of Socio-Scientific Issue (SSI) based teaching in a science classroom setting. We designed our research in two phases. The first phase examined pre-service science teachers' perceptions about using social media to promote their SSI-based teaching. The…

Turkish Preservice Science Teachers' Socioscientific Issues-Based Teaching Practices in Middle School Science Classrooms

ERIC Educational Resources Information Center

Genel, Abdulkadir; Topçu, Mustafa Sami

2016-01-01

Background: Despite a growing body of research and curriculum reforms including socioscientific issues (SSI) across the world, how preservice science teachers (PST) or in-service science teachers can teach SSI in science classrooms needs further inquiry. Purpose: The purpose of this study is to describe the abilities of PSTs to teach SSI in middle…

20 CFR 416.1816 - Information we need concerning marriage when you apply for SSI.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Information we need concerning marriage when....1816 Information we need concerning marriage when you apply for SSI. When you apply for SSI benefits... are living in the same household with anyone of the opposite sex who is not related to you. If you are...

20 CFR 416.1816 - Information we need concerning marriage when you apply for SSI.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Information we need concerning marriage when....1816 Information we need concerning marriage when you apply for SSI. When you apply for SSI benefits... are living in the same household with anyone of the opposite sex who is not related to you. If you are...

20 CFR 416.1816 - Information we need concerning marriage when you apply for SSI.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Information we need concerning marriage when....1816 Information we need concerning marriage when you apply for SSI. When you apply for SSI benefits... are living in the same household with anyone of the opposite sex who is not related to you. If you are...

20 CFR 416.1816 - Information we need concerning marriage when you apply for SSI.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Information we need concerning marriage when....1816 Information we need concerning marriage when you apply for SSI. When you apply for SSI benefits... are living in the same household with anyone of the opposite sex who is not related to you. If you are...

20 CFR 416.1816 - Information we need concerning marriage when you apply for SSI.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Information we need concerning marriage when....1816 Information we need concerning marriage when you apply for SSI. When you apply for SSI benefits... are living in the same household with anyone of the opposite sex who is not related to you. If you are...

Moral Sensitivity in the Context of Socioscientific Issues in High School Science Students

ERIC Educational Resources Information Center

Fowler, Samantha R.; Zeidler, Dana L.; Sadler, Troy D.

2009-01-01

This study is a part of a larger study that examined using socioscientific issues (SSI) as a form of effective science teaching. The purpose was to investigate how teaching a year-long curriculum using SSI affects science learning outcomes. In this report, we examine the effects of a SSI-driven curriculum on the development of students' moral…

Categorization of Digital Games in English Language Learning Studies: Introducing the SSI Model

ERIC Educational Resources Information Center

Sundqvist, Pia

2013-01-01

The main aim of the present paper is to introduce a model for digital game categorization suitable for use in English language learning studies: the Scale of Social Interaction (SSI) Model (original idea published as Sundqvist, 2013). The SSI Model proposes a classification of commercial off-the-shelf (COTS) digital games into three categories:…

A Framework for Teachers' Assessment of Socio-Scientific Argumentation: An Example Using the GMO Issue

ERIC Educational Resources Information Center

Christenson, Nina; Chang Rundgren, Shu-Nu

2015-01-01

Socio-scientific issues (SSI) have proven to be suitable contexts for students to actively reflect on and argue about complex social issues related to science. Research has indicated that explicitly teaching SSI argumentation is a good way to help students develop their argumentation skills and make them aware of the complexity of SSI. However,…

Resistance to Dialogic Discourse in SSI Teaching: The Effects of an Argumentation-Based Workshop, Teaching Practicum, and Induction on a Preservice Science Teacher

ERIC Educational Resources Information Center

Kilinc, Ahmet; Demiral, Umit; Kartal, Tezcan

2017-01-01

Teaching socioscientific issues (SSI) necessitates dialogic discourse activities. However, a majority of science teachers prefer monologic discourse in SSI contexts. In addition, some of these teachers are resistant to change (from monologic to dialogic discourse) despite certain professional development attempts. The purpose of the present…

DoSSiER: Database of scientific simulation and experimental results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wenzel, Hans; Yarba, Julia; Genser, Krzystof

The Geant4, GeantV and GENIE collaborations regularly perform validation and regression tests for simulation results. DoSSiER (Database of Scientific Simulation and Experimental Results) is being developed as a central repository to store the simulation results as well as the experimental data used for validation. DoSSiER can be easily accessed via a web application. In addition, a web service allows for programmatic access to the repository to extract records in json or xml exchange formats. In this paper, we describe the functionality and the current status of various components of DoSSiER as well as the technology choices we made.

DoSSiER: Database of scientific simulation and experimental results

DOE PAGES

Wenzel, Hans; Yarba, Julia; Genser, Krzystof; ...

2016-08-01

The Geant4, GeantV and GENIE collaborations regularly perform validation and regression tests for simulation results. DoSSiER (Database of Scientific Simulation and Experimental Results) is being developed as a central repository to store the simulation results as well as the experimental data used for validation. DoSSiER can be easily accessed via a web application. In addition, a web service allows for programmatic access to the repository to extract records in json or xml exchange formats. In this paper, we describe the functionality and the current status of various components of DoSSiER as well as the technology choices we made.

Evaluation of New Cleanup Agents for Analysis of Pesticide Residues in Tea.

PubMed

Ueda, Yuko; Honda, Katsuhisa

2017-01-01

We evaluated the effectiveness of new cleanup agents (S-NH 2 and S-Si) compared with other previously reported cleanup agents (octadecylsilane, graphitized carbon, aminopropyl and silica gel) for removal of interfering substances such as catechin and caffeine prior to analysis of pesticide residues in tea. S-NH 2 and S-Si were highly efficient in removal of catechin and caffeine, respectively. Recoveries of 80 pesticides using S-NH 2 and S-Si were tested, and more than 70% of pesticides showed recovery greater than 70%. These results indicate that S-NH 2 and S-Si agents will be useful for analysis of pesticide residues in tea.

Study on soil-pile-structure-TMD interaction system by shaking table model test

NASA Astrophysics Data System (ADS)

Lou, Menglin; Wang, Wenjian

2004-06-01

The success of the tuned mass damper (TMD) in reducing wind-induced structural vibrations has been well established. However, from most of the recent numerical studies, it appears that for a structure situated on very soft soil, soil-structure interaction (SSI) could render a damper on the structure totally ineffective. In order to experimentally verify the SSI effect on the seismic performance of TMD, a series of shaking table model tests have been conducted and the results are presented in this paper. It has been shown that the TMD is not as effective in controlling the seismic responses of structures built on soft soil sites due to the SSI effect. Some test results also show that a TMD device might have a negative impact if the SSI effect is neglected and the structure is built on a soft soil site. For structures constructed on a soil foundation, this research verifies that the SSI effect must be carefully understood before a TMD control system is designed to determine if the control is necessary and if the SSI effect must be considered when choosing the optimal parameters of the TMD device.

Seismic Response of Steel Braced Building Frame Considering Soil Structure Interaction (SSI): An Experimental Study

NASA Astrophysics Data System (ADS)

Hirave, Vivek; Kalyanshetti, Mahesh

2018-02-01

Conventional fixed-base analysis ignoring the effect of soil-flexibility may result in unsafe design. Therefore, to evaluate the realistic behavior of structure the soil structure interaction (SSI) effect shall be incorporated in the analysis. In seismic analysis, provision of bracing system is one of the important option for the structure to have sufficient strength with adequate stiffness to resist lateral forces. The different configuration of these bracing systems alters the response of buildings, and therefore, it is important to evaluate the most effective bracing systems in view point of stability against SSI effect. In present study, three RC building frames, G+3, G+5 and G+7 and their respective scaled down steel model with two types of steel bracing system incorporating the effect of soil flexibility is considered for experimental and analytical study. The analytical study is carried out using Elastic continuum approach and the experimental study is carried out using Shake Table. The influence of SSI on various seismic parameters is presented. The study reveals that, steel bracing system is beneficial to control SSI effect and it is observed that V bracing is more effective, in resisting seismic load considering SSI.

Contextualizing Nature of Science Instruction in Socioscientific Issues

NASA Astrophysics Data System (ADS)

Eastwood, Jennifer Lynne; Sadler, Troy D.; Zeidler, Dana L.; Lewis, Anna; Amiri, Leila; Applebaum, Scott

2012-10-01

The purpose of this study was to investigate the effects of two learning contexts for explicit-reflective nature of science (NOS) instruction, socioscientific issues (SSI) driven and content driven, on student NOS conceptions. Four classes of 11th and 12th grade anatomy and physiology students participated. Two classes experienced a curricular sequence organized around SSI (the SSI group), and two classes experienced a content-based sequence (the Content group). An open-ended NOS questionnaire was administered to both groups at the beginning and end of the school year and analyzed to generate student profiles. Quantitative analyses were performed to compare pre-instruction NOS conceptions between groups as well as pre to post changes within groups and between groups. Both SSI and Content groups showed significant gains in most NOS themes, but between-group gains were not significantly different. Qualitative analysis of post-instruction responses, however, revealed that students in the SSI group tended to use examples to describe their views of the social/cultural NOS. The findings support SSI contexts as effective for promoting gains in students' NOS understanding and suggest that these contexts facilitate nuanced conceptions that should be further explored.

Risk factors and outcomes of organ-space surgical site infections after elective colon and rectal surgery.

PubMed

Gomila, Aina; Carratalà, Jordi; Camprubí, Daniel; Shaw, Evelyn; Badia, Josep Mª; Cruz, Antoni; Aguilar, Francesc; Nicolás, Carmen; Marrón, Anna; Mora, Laura; Perez, Rafel; Martin, Lydia; Vázquez, Rosa; Lopez, Ana Felisa; Limón, Enric; Gudiol, Francesc; Pujol, Miquel

2017-01-01

Organ-space surgical site infections (SSI) are the most serious and costly infections after colorectal surgery. Most previous studies of risk factors for SSI have analysed colon and rectal procedures together. The aim of the study was to determine whether colon and rectal procedures have different risk factors and outcomes for organ-space SSI. A multicentre observational prospective cohort study of adults undergoing elective colon and rectal procedures at 10 Spanish hospitals from 2011 to 2014. Patients were followed up until 30 days post-surgery. Surgical site infection was defined according to the Centers for Disease Control and Prevention criteria. Oral antibiotic prophylaxis (OAP) was considered as the administration of oral antibiotics the day before surgery combined with systemic intravenous antibiotic prophylaxis. Of 3,701 patients, 2,518 (68%) underwent colon surgery and 1,183 (32%) rectal surgery. In colon surgery, the overall SSI rate was 16.4% and the organ-space SSI rate was 7.9%, while in rectal surgery the rates were 21.6% and 11.5% respectively ( p  < 0.001). Independent risk factors for organ-space SSI in colon surgery were male sex (Odds ratio -OR-: 1.57, 95% CI: 1.14-2.15) and ostomy creation (OR: 2.65, 95% CI: 1.8-3.92) while laparoscopy (OR: 0.5, 95% CI: 0.38-0.69) and OAP combined with intravenous antibiotic prophylaxis (OR: 0.7, 95% CI: 0.51-0.97) were protective factors. In rectal surgery, independent risk factors for organ-space SSI were male sex (OR: 2.11, 95% CI: 1.34-3.31) and longer surgery (OR: 1.49, 95% CI: 1.03-2.15), whereas OAP with intravenous antibiotic prophylaxis (OR: 0.49, 95% CI: 0.32-0.73) was a protective factor. Among patients with organ-space SSI, we found a significant difference in the overall 30-day mortality, being higher in colon surgery than in rectal surgery (11.5% vs 5.1%, p  = 0.04). Organ-space SSI in colon and rectal surgery has some differences in terms of incidence, risk factors and outcomes. These differences could be considered for surveillance purposes and for the implementation of preventive strategies. Administration of OAP would be an important measure to reduce the OS-SSI rate in both colon and rectal surgeries.

Costs Associated With Surgical Site Infections in Veterans Affairs Hospitals.

PubMed

Schweizer, Marin L; Cullen, Joseph J; Perencevich, Eli N; Vaughan Sarrazin, Mary S

2014-06-01

Surgical site infections (SSIs) are potentially preventable complications that are associated with excess morbidity and mortality. To determine the excess costs associated with total, deep, and superficial SSIs among all operations and for high-volume surgical specialties. Surgical patients from 129 Veterans Affairs (VA) hospitals were included. The Veterans Health Administration Decision Support System and VA Surgical Quality Improvement Program databases were used to assess costs associated with SSIs among VA patients who underwent surgery in fiscal year 2010. Linear mixed-effects models were used to evaluate incremental costs associated with SSIs, controlling for patient risk factors, surgical risk factors, and hospital-level variation in costs. Costs of the index hospitalization and subsequent 30-day readmissions were included. Additional analysis determined potential cost savings of quality improvement programs to reduce SSI rates at hospitals with the highest risk-adjusted SSI rates. Among 54,233 VA patients who underwent surgery, 1756 (3.2%) experienced an SSI. Overall, 0.8% of the cohort had a deep SSI, and 2.4% had a superficial SSI. The mean unadjusted costs were $31,580 and $52,620 for patients without and with an SSI, respectively. In the risk-adjusted analyses, the relative costs were 1.43 times greater for patients with an SSI than for patients without an SSI (95% CI, 1.34-1.52; difference, $11,876). Deep SSIs were associated with 1.93 times greater costs (95% CI, 1.71-2.18; difference, $25,721), and superficial SSIs were associated with 1.25 times greater costs (95% CI, 1.17-1.35; difference, $7003). Among the highest-volume specialties, the greatest mean cost attributable to SSIs was $23,755 among patients undergoing neurosurgery, followed by patients undergoing orthopedic surgery, general surgery, peripheral vascular surgery, and urologic surgery. If hospitals in the highest 10th percentile (ie, the worst hospitals) reduced their SSI rates to the rates of the hospitals in the 50th percentile, the Veterans Health Administration would save approximately $6.7 million per year. Surgical site infections are associated with significant excess costs. Among analyzed surgery types, deep SSIs and SSIs among neurosurgery patients are associated with the highest risk-adjusted costs. Large potential savings per year may be achieved by decreasing SSI rates.

Upscaling key ecosystem functions across the conterminous United States by a water-centric ecosystem model

NASA Astrophysics Data System (ADS)

Sun, Ge; Caldwell, Peter; Noormets, Asko; McNulty, Steven G.; Cohen, Erika; Moore Myers, Jennifer; Domec, Jean-Christophe; Treasure, Emrys; Mu, Qiaozhen; Xiao, Jingfeng; John, Ranjeet; Chen, Jiquan

2011-09-01

We developed a water-centric monthly scale simulation model (WaSSI-C) by integrating empirical water and carbon flux measurements from the FLUXNET network and an existing water supply and demand accounting model (WaSSI). The WaSSI-C model was evaluated with basin-scale evapotranspiration (ET), gross ecosystem productivity (GEP), and net ecosystem exchange (NEE) estimates by multiple independent methods across 2103 eight-digit Hydrologic Unit Code watersheds in the conterminous United States from 2001 to 2006. Our results indicate that WaSSI-C captured the spatial and temporal variability and the effects of large droughts on key ecosystem fluxes. Our modeled mean (±standard deviation in space) ET (556 ± 228 mm yr-1) compared well to Moderate Resolution Imaging Spectroradiometer (MODIS) based (527 ± 251 mm yr-1) and watershed water balance based ET (571 ± 242 mm yr-1). Our mean annual GEP estimates (1362 ± 688 g C m-2 yr-1) compared well (R2 = 0.83) to estimates (1194 ± 649 g C m-2 yr-1) by eddy flux-based EC-MOD model, but both methods led significantly higher (25-30%) values than the standard MODIS product (904 ± 467 g C m-2 yr-1). Among the 18 water resource regions, the southeast ranked the highest in terms of its water yield and carbon sequestration capacity. When all ecosystems were considered, the mean NEE (-353 ± 298 g C m-2 yr-1) predicted by this study was 60% higher than EC-MOD's estimate (-220 ± 225 g C m-2 yr-1) in absolute magnitude, suggesting overall high uncertainty in quantifying NEE at a large scale. Our water-centric model offers a new tool for examining the trade-offs between regional water and carbon resources under a changing environment.

Ground-based observations of 951 Gaspra: CCD lightcurves and spectrophotometry with the Galileo filters

NASA Technical Reports Server (NTRS)

Mottola, Stefano; Dimartino, M.; Gonano-Beurer, M.; Hoffmann, H.; Neukum, G.

1992-01-01

This paper reports the observations of 951 Gaspra carried out at the European Southern Observatory (La Silla, Chile) during the 1991 apparition, using the DLR CCD Camera equipped with a spare set of the Galileo SSI filters. Time-resolved spectrophotometric measurements are presented. The occurrence of spectral variations with rotation suggests the presence of surface variegation.

Development of Standard Station Interface for Comprehensive Nuclear Test Ban Treaty Organistation Monitoring Networks

NASA Astrophysics Data System (ADS)

Dricker, I. G.; Friberg, P.; Hellman, S.

2001-12-01

Under the contract with the CTBTO, Instrumental Software Technologies Inc., (ISTI) has designed and developed a Standard Station Interface (SSI) - a set of executable programs and application programming interface libraries for acquisition, authentication, archiving and telemetry of seismic and infrasound data for stations of the CTBTO nuclear monitoring network. SSI (written in C) is fully supported under both the Solaris and Linux operating systems and will be shipped with fully documented source code. SSI consists of several interconnected modules. The Digitizer Interface Module maintains a near-real-time data flow between multiple digitizers and the SSI. The Disk Buffer Module is responsible for local data archival. The Station Key Management Module is a low-level tool for data authentication and verification of incoming signatures. The Data Transmission Module supports packetized near-real-time data transmission from the primary CTBTO stations to the designated Data Center. The AutoDRM module allows transport of seismic and infrasound signed data via electronic mail (auxiliary station mode). The Command Interface Module is used to pass the remote commands to the digitizers and other modules of SSI. A station operator has access to the state-of-health information and waveforms via an the Operator Interface Module. Modular design of SSI will allow painless extension of the software system within and outside the boundaries of CTBTO station requirements. Currently an alpha version of SSI undergoes extensive tests in the lab and onsite.

The Soy Isoflavones for Reducing Bone Loss (SIRBL) Study: Three year effects on pQCT bone mineral density and strength measures in postmenopausal women

PubMed Central

SHEDD-WISE, KRISTINE M.; ALEKEL, D. LEE; HOFMANN, HEIKE; HANSON, KATHY B.; SCHIFERL, DAN J.; HANSON, LAURA N.; VAN LOAN, MARTA D.

2011-01-01

Soy isoflavones exert inconsistent bone density-preserving effects, but the bone strength-preserving effects in humans are unknown. Our double-blind randomized controlled trial examined two soy isoflavone doses (80 or 120 mg/d) vs placebo tablets on volumetric bone mineral density (vBMD) and strength (via peripheral quantitative computed tomography) in healthy postmenopausal women (46–63 y). We measured 3 y change in cortical (Ct) BMD, cortical thickness (CtThk), periosteal circumference (PC), endosteal circumference (EC), and strength-strain index (SSI) at 1/3 midshaft femur (N=171) and trabecular (Tb) BMD, PC, and SSI at 4% distal tibia (N=162). We found no treatment effect on femur CtThk, PC, or EC, or tibia TbBMD or PC. Strongest predictors (negative) of tibia TbBMD and SSI and femur CtBMD were timepoint and bone resorption; whole body fat mass was protective of SSI. As time since last menstrual period (TLMP) increased (p=0.012), 120 mg/d was protective of CtBMD. Strongest predictors of femur SSI were timepoint, bone resorption, and TLMP (protective). Isoflavone tablets were negative predictors of SSI, but 80 mg/d became protective as bone turnover increased (p=0.011). Soy isoflavone treatment for 3 y was modestly beneficial for midshaft femur vBMD as TLMP increased, and for midshaft femur SSI as bone turnover increased. PMID:21295742

Quantifying solar spectral irradiance in aquatic habitats for the assessment of photoenhanced toxicity

USGS Publications Warehouse

Barron, M.G.; Little, E.E.; Calfee, R.; Diamond, S.

2000-01-01

The spectra and intensity of solar radiation (solar spectral irradiance [SSI]) was quantified in selected aquatic habitats in the vicinity of an oil field on the California coast. Solar spectral irradiance measurements consisted of spectral scans (280–700 nm) and radiometric measurements of ultraviolet (UV): UVB (280–320 nm) and UVA (320–400 nm). Solar spectral irradiance measurements were taken at the surface and at various depths in two marsh ponds, a shallow wetland, an estuary lagoon, and the intertidal area of a high-energy sandy beach. Daily fluctuation in SSI showed a general parabolic relationship with time; maximum structure–activity relationship (SAR) was observed at approximate solar noon. Solar spectral irradiance measurements taken at 10-cm depth at approximate solar noon in multiple aquatic habitats exhibited only a twofold variation in visible light and UVA and a 4.5-fold variation in UVB. Visible light ranged from 11,000 to 19,000 μW/cm2, UVA ranged from 460 to 1,100 μW/cm2, and UVB ranged from 8.4 to 38 μW/cm2. In each habitat, the attenuation of light intensity with increasing water depth was differentially affected over specific wavelengths of SSI. The study results allowed the development of environmentally realistic light regimes necessary for photoenhanced toxicity studies.

False Color Aurora

NASA Image and Video Library

1997-09-23

Data from NASA's Galileo spacecraft were used to produce this false-color composite of Jupiter's northern aurora on the night side of the planet. The height of the aurora, the thickness of the auroral arc, and the small-scale structure are revealed for the first time. Images in Galileo's red, green, and clear filters are displayed in red, green, and blue respectively. The smallest resolved features are tens of kilometers in size, which is a ten-fold improvement over Hubble Space Telescope images and a hundred-fold improvement over ground-based images. The glow is caused by electrically charged particles impinging on the atmosphere from above. The particles travel along Jupiter's magnetic field lines, which are nearly vertical at this latitude. The auroral arc marks the boundary between the "closed" field lines that are attached to the planet at both ends and the "open" field lines that extend out into interplanetary space. At the boundary the particles have been accelerated over the greatest distances, and the glow is especially intense. The latitude-longitude lines refer to altitudes where the pressure is 1 bar. The image shows that the auroral emissions originate about 500 kilometers (about 310 miles) above this surface. The colored background is light scattered from Jupiter's bright crescent, which is out of view to the right. North is at the top. The images are centered at 57 degrees north and 184 degrees west and were taken on April 2, 1997 at a range of 1.7 million kilometers (1.05 million miles) by Galileo's Solid State Imaging (SSI) system. http://photojournal.jpl.nasa.gov/catalog/PIA00603

View of Socioscientific Issues among Educators: The Willingness of Teachers to Accept SSI into the Classroom and the Reasoning Underyling Those Beliefs

ERIC Educational Resources Information Center

Parr, John Carlos

2013-01-01

Socioscientific issues (SSI) are potentially controversial topics, which can be examined using a social and a scientific perspective. The inclusion of these topics in elementary and secondary classrooms has caused a number of conflicts over the past century. In the present study, I explore the willingness of teachers to include three SSI:…

FoSSI: the family of simplified solver interfaces for the rapid development of parallel numerical atmosphere and ocean models

NASA Astrophysics Data System (ADS)

Frickenhaus, Stephan; Hiller, Wolfgang; Best, Meike

The portable software FoSSI is introduced that—in combination with additional free solver software packages—allows for an efficient and scalable parallel solution of large sparse linear equations systems arising in finite element model codes. FoSSI is intended to support rapid model code development, completely hiding the complexity of the underlying solver packages. In particular, the model developer need not be an expert in parallelization and is yet free to switch between different solver packages by simple modifications of the interface call. FoSSI offers an efficient and easy, yet flexible interface to several parallel solvers, most of them available on the web, such as PETSC, AZTEC, MUMPS, PILUT and HYPRE. FoSSI makes use of the concept of handles for vectors, matrices, preconditioners and solvers, that is frequently used in solver libraries. Hence, FoSSI allows for a flexible treatment of several linear equations systems and associated preconditioners at the same time, even in parallel on separate MPI-communicators. The second special feature in FoSSI is the task specifier, being a combination of keywords, each configuring a certain phase in the solver setup. This enables the user to control a solver over one unique subroutine. Furthermore, FoSSI has rather similar features for all solvers, making a fast solver intercomparison or exchange an easy task. FoSSI is a community software, proven in an adaptive 2D-atmosphere model and a 3D-primitive equation ocean model, both formulated in finite elements. The present paper discusses perspectives of an OpenMP-implementation of parallel iterative solvers based on domain decomposition methods. This approach to OpenMP solvers is rather attractive, as the code for domain-local operations of factorization, preconditioning and matrix-vector product can be readily taken from a sequential implementation that is also suitable to be used in an MPI-variant. Code development in this direction is in an advanced state under the name ScOPES: the Scalable Open Parallel sparse linear Equations Solver.

Lessons Learned from Unfavorable Microsurgical Head and Neck Reconstruction: Japan National Cancer Center Hospital and Okayama University Hospital.

PubMed

Kimata, Yoshihiro; Matsumoto, Hiroshi; Sugiyama, Narusi; Onoda, Satoshi; Sakuraba, Minoru

2016-10-01

The risk of surgical site infection (SSI) remains high after major reconstructive surgery of the head and neck. Clinical data regarding SSI in microsurgical tongue reconstruction are described at National Cancer Hospital in Japan, including discussions of unfavorable representative cases, the relationship between SSI and preoperative irradiation at Okayama University Hospital in Japan, and strategies for SSI control in head and neck reconstruction. Local complications are inevitable in patients undergoing reconstruction in the head and neck areas. The frequency of major complications can be decreased, and late postoperative complications can be prevented with the help of appropriate methods. Copyright © 2016 Elsevier Inc. All rights reserved.

Overview of the production of sintered SiC optics and optical sub-assemblies

NASA Astrophysics Data System (ADS)

Williams, S.; Deny, P.

2005-08-01

The following is an overview on sintered silicon carbide (SSiC) material properties and processing requirements for the manufacturing of components for advanced technology optical systems. The overview will compare SSiC material properties to typical materials used for optics and optical structures. In addition, it will review manufacturing processes required to produce optical components in detail by process step. The process overview will illustrate current manufacturing process and concepts to expand the process size capability. The overview will include information on the substantial capital equipment employed in the manufacturing of SSIC. This paper will also review common in-process inspection methodology and design rules. The design rules are used to improve production yield, minimize cost, and maximize the inherent benefits of SSiC for optical systems. Optimizing optical system designs for a SSiC manufacturing process will allow systems designers to utilize SSiC as a low risk, cost competitive, and fast cycle time technology for next generation optical systems.

Validation of COLA score for predicting wound infection in patients undergoing surgery for rectal cancer.

PubMed

Saylam, Baris; Tez, Mesut; Comcali, Bulent; Vural, Veli; Duzgun, Arife Polat; Ozer, Mehmet Vasfi; Coskun, Faruk

2017-01-01

The purpose of our study was to estimate the incidence of SSI (Surgical site infection) and the effect of COLA (contamination, obesity, laparotomy and ASA grade) score on SSI in patients undergoing rectal surgical procedures for rectal cancer. A total of 92 patients who underwent operation for rectum cancer were enrolled in this study. Wound surveillance was performed in all patients by a staff surgeon identified infected wounds during the hospital stay, and collected information for up to 30 days after operation. The overall rate of incisional SSI and organ/space SSI was 22.8% and 7.6% respectively. Surgical site infection rates were 14.2%, 20.58%, 40.7%, 57.1% for COLA 1,2,3 and 4 scores respectively. The area under the receiver/ operator characteristic curve for the score was 0,660. COLA scoring systems predict, with reasonable accuracy, the risk of SSI in rectal cancer patients undergoing elective rectal surgery. COLA score Rectal surgery, Surgical site infection, Risk prediction, Wound infection.

PTSD and key somatic complaints and cultural syndromes among rural Cambodians: the results of a needs assessment survey.

PubMed

Hinton, Devon E; Hinton, Alexander L; Eng, Kok-Thay; Choung, Sophearith

2012-09-01

This article describes a culturally sensitive assessment tool for traumatized Cambodians, the Cambodian "Somatic Symptom and Syndrome Inventory" (SSI), and reports the outcome of a needs assessment conducted in rural Cambodia using the instrument. Villagers locally identified (N = 139) as still suffering the effects of the Pol Pot genocide were evaluated. All 139 had post-traumatic stress disorder (PTSD) as assessed by the PTSD Checklist (PCL), and they had elevated SSI scores. The severity of the SSI items varied by level of PTSD severity, and several items--for example, dizziness, dizziness on standing, khyâl (a windlike substance) attacks, and "thinking a lot"--were extremely elevated in those participants with higher levels of PTSD. The SSI was more highly correlated to self-perceived health (Short Form Health Survey-3) and past trauma events (Harvard Trauma Questionnaire) than was the PCL. The study shows the SSI items to be a core aspect of the Cambodian trauma ontology.

Use of surveillance data to identify target populations for Staphylococcus aureus vaccines and prevent surgical site infections: A pilot study

PubMed Central

Gustin, Marie-Paule; Giard, Marine; Bénet, Thomas; Vanhems, Philippe

2015-01-01

The development of anti-staphylococcal vaccines is nowadays a priority to prevent surgical site infections (SSI). The objective of the present study was to identify a potential target population by assessing surveillance data on surgery patients for possible anti-staphylococcal vaccine administration. Individuals at high risk of SSI by Staphylococcus aureus (SA) were targeted by the French SSI Surveillance Network in south-eastern France between 2008 and 2011. Among 238,470 patients, those undergoing primary total hip replacement appeared to be an interesting and healthy enough population for anti-staphylococcal vaccine testing. These male patients, subjected to multiple procedures and with American Society of Anesthesiologists score >2, had a probability of SA SSI about 21 times higher than females with no severe systemic disease and no multiple procedures. Our study indicates that surveillance data on SSI might be an interesting epidemiological source for planning vaccine trials to prevent nosocomial infections. PMID:25668663

Efficacy of Negative Pressure Wound Treatment in Preventing Surgical Site Infections after Whipple Procedures.

PubMed

Gupta, Ryan; Darby, Geoffrey C; Imagawa, David K

2017-10-01

Surgical site infections (SSIs) occur at an average rate of 21.1 per cent after Whipple procedures per NSQIP data. In the setting of adherence to standard National Surgery Quality Improvement Program (NSQIP) Hepatopancreatobiliary recommendations including wound protector use and glove change before closing, this study seeks to evaluate the efficacy of using negative pressure wound treatment (NPWT) over closed incision sites after a Whipple procedure to prevent SSI formation. We retrospectively examined consecutive patients from January 2014 to July 2016 who met criteria of completing Whipple procedures with full primary incision closure performed by a single surgeon at a single institution. Sixty-one patients were included in the study between two cohorts: traditional dressing (TD) (n = 36) and NPWT dressing (n = 25). There was a statistically significant difference (P = 0.01) in SSI formation between the TD cohort (n = 15, SSI rate = 0.41) and the NPWT cohort (n = 3, SSI rate = 0.12). The adjusted odds ratio (OR) of SSI formation was significant for NPWT use [OR = 0.15, P = 0.036] and for hospital length of stay [OR = 1.21, P = 0.024]. Operative length, operative blood loss, units of perioperative blood transfusion, intraoperative gastrojejunal tube placement, preoperative stent placement, and postoperative antibiotic duration did not significantly impact SSI formation (P > 0.05).

Intrajudge and Interjudge Reliability of the Stuttering Severity Instrument-Fourth Edition.

PubMed

Davidow, Jason H; Scott, Kathleen A

2017-11-08

The Stuttering Severity Instrument (SSI) is a tool used to measure the severity of stuttering. Previous versions of the instrument have known limitations (e.g., Lewis, 1995). The present study examined the intra- and interjudge reliability of the newest version, the Stuttering Severity Instrument-Fourth Edition (SSI-4) (Riley, 2009). Twelve judges who were trained on the SSI-4 protocol participated. Judges collected SSI-4 data while viewing 4 videos of adults who stutter at Time 1 and 4 weeks later at Time 2. Data were analyzed for intra- and interjudge reliability of the SSI-4 subscores (for Frequency, Duration, and Physical Concomitants), total score, and final severity rating. Intra- and interjudge reliability across the subscores and total score concurred with the manual's reported reliability when reliability was calculated using the methods described in the manual. New calculations of judge agreement produced different values from those in the manual-for the 3 subscores, total score, and final severity rating-and provided data absent from the manual. Clinicians and researchers who use the SSI-4 should carefully consider the limitations of the instrument. Investigation into the multitasking demands of the instrument may provide information on whether separating the collection of data for specific variables will improve intra- and interjudge reliability of those variables.

Leading causes of certifiable visual loss in England and Wales during the year ending 31 March 2013.

PubMed

Quartilho, A; Simkiss, P; Zekite, A; Xing, W; Wormald, R; Bunce, C

2016-04-01

The last article on causes of sight impairment (SI) in England and Wales was for April 2007-March 2008. This report updates these figures for April 2012-March 2013. In England and Wales, registration for SI is initiated by completion of a certificate of vision impairment (CVI). The main cause of visual impairment was ascertained for certificates completed April 2012-March 2013. A proportional comparison against April 2007-March 2008 was made. We received 24 009 CVIs of which 10 410 were for severe sight impairment (SSI) and 13 129 were for SI. These numbers were slightly higher than those observed in April 2007-March 2008 (9823 SSI; 12 607 SI). The ratio SI:SSI has remained static with 55% of all certifications being SI. The proportion of certificates without a single main cause has fallen slightly (16.6 to 14%). The proportion of certificates with a main cause of degeneration of the macula and posterior pole (mostly age-related macular degeneration (AMD)) decreased from 58.6 to 50% SSI and from 57.2 to 52.5% SI. Glaucoma remains the second most common cause (11% SSI; 7.6% SI) but hereditary retinal disorders overtook diabetes as third leading cause of SSI. AMD is still by far the leading cause of certifications for sight impairment in England and Wales (both SI and SSI). Proportionate changes have been observed since 2008, but it is important to note that a proportionate increase in one condition will impact on others.

Antibiotic prophylaxis and incisional surgical site infection following colorectal cancer surgery: an analysis of 330 cases.

PubMed

Lohsiriwat, Varut; Lohsiriwat, Darin

2009-01-01

To evaluate the rate of incisional surgical site infection (SSI) following colorectal cancer surgery in a university hospital and to determine whether duration of prophylactic antibiotic administration can affect the development of this complication. The medical records of 330 patients with colorectal cancer undergoing elective oncological resection between 2003 and 2006 at Siriraj Hospital were reviewed. Patients were divided into two groups according to the duration of antibiotic administration; group A: prophylactic antibiotics were discontinued within 24 hours after surgery and group B: antibiotics administration was extended beyond 24 hours after surgery. Data including rate of incisional SSI were analyzed. There were 180 males and 150 females, with a mean age of 63 years. There were 126 patients (38%) in group A and 204 patients (62%) in group B. There was no statistical difference in patient characteristics and tumor-related variables between the two groups, except tumor location. Overall rate of incisional SSI was 14.5%. The rate of incisional SSI was not statistically different between the two groups (group A 11.1% vs. group B 16.7%, p = 0.22). Patients with incisional SSI had a significantly longer hospital stay than patients without incisional SSI (15.9 vs. 8.3 days, p < 0.001). This present study found the overall rate of incisional SSI following colorectal surgery to be 14.5%. There was no significant difference in the rate of this complication between the two groups. Thus, surgeons should be encouraged to use a shorter duration of antibiotics to prevent the emergence of antibiotic-resistant bacterial infection and reduce hospital expenditure.

Evaluating impacts of different longitudinal driver assistance systems on reducing multi-vehicle rear-end crashes during small-scale inclement weather.

PubMed

Li, Ye; Xing, Lu; Wang, Wei; Wang, Hao; Dong, Changyin; Liu, Shanwen

2017-10-01

Multi-vehicle rear-end (MVRE) crashes during small-scale inclement (SSI) weather cause high fatality rates on freeways, which cannot be solved by traditional speed limit strategies. This study aimed to reduce MVRE crash risks during SSI weather using different longitudinal driver assistance systems (LDAS). The impact factors on MVRE crashes during SSI weather were firstly analyzed. Then, four LDAS, including Forward collision warning (FCW), Autonomous emergency braking (AEB), Adaptive cruise control (ACC) and Cooperative ACC (CACC), were modeled based on a unified platform, the Intelligent Driver Model (IDM). Simulation experiments were designed and a large number of simulations were then conducted to evaluate safety effects of different LDAS. Results indicate that the FCW and ACC system have poor performance on reducing MVRE crashes during SSI weather. The slight improvement of sight distance of FCW and the limitation of perception-reaction time of ACC lead the failure of avoiding MVRE crashes in most scenarios. The AEB system has the better effect due to automatic perception and reaction, as well as performing the full brake when encountering SSI weather. The CACC system has the best performance because wireless communication provides a larger sight distance and a shorter time delay at the sub-second level. Sensitivity analyses also indicated that the larger number of vehicles and speed changes after encountering SSI weather have negative impacts on safety performances. Results of this study provide useful information for accident prevention during SSI weather. Copyright © 2017 Elsevier Ltd. All rights reserved.

The soy isoflavones for reducing bone loss study: 3-yr effects on pQCT bone mineral density and strength measures in postmenopausal women.

PubMed

Shedd-Wise, Kristine M; Alekel, D Lee; Hofmann, Heike; Hanson, Kathy B; Schiferl, Dan J; Hanson, Laura N; Van Loan, Marta D

2011-01-01

Soy isoflavones exert inconsistent bone density-preserving effects, but the bone strength-preserving effects in humans are unknown. Our double-blind randomized controlled trial examined 2 soy isoflavone doses (80 or 120mg/d) vs placebo tablets on volumetric bone mineral density (vBMD) and strength (by means of peripheral quantitative computed tomography) in healthy postmenopausal women (46-63yr). We measured 3-yr changes in cortical BMD (CtBMD), cortical thickness (CtThk), periosteal circumference (PC), endosteal circumference (EC), and strength-strain index (SSI) at 1/3 midshaft femur (N=171), and trabecular BMD (TbBMD), PC, and SSI at 4% distal tibia (N=162). We found no treatment effect on femur CtThk, PC, or EC, or tibia TbBMD or PC. The strongest predictors (negative) of tibia TbBMD and SSI and femur CtBMD were timepoint and bone resorption; whole-body fat mass was protective of SSI. As time since last menstrual period (TLMP) increased (p=0.012), 120-mg/d dose was protective of CtBMD. The strongest predictors of femur SSI were timepoint, bone resorption, and TLMP (protective). Isoflavone tablets were negative predictors of SSI, but 80-mg/d dose became protective as bone turnover increased (p=0.011). Soy isoflavone treatment for 3yr was modestly beneficial for midshaft femur vBMD as TLMP increased and for midshaft femur SSI as bone turnover increased. Copyright © 2011 The International Society for Clinical Densitometry. Published by Elsevier Inc. All rights reserved.

Impact of case-relevant and case-irrelevant communication within the surgical team on surgical-site infection.

PubMed

Tschan, F; Seelandt, J C; Keller, S; Semmer, N K; Kurmann, A; Candinas, D; Beldi, G

2015-12-01

Surgical-site infections (SSIs) are the most common complications after surgery. An influence from talking and distractions during surgery on patient outcomes has been suggested, but there is limited evidence. The aim of this prospective observational study was to assess the relationship between intraoperative communication within the surgical team and SSI, and between intraoperative distractions and SSI. This prospective observational study included patients undergoing elective, open abdominal procedures. For each procedure, intraoperative case-relevant and case-irrelevant communication, and intraoperative distractions were observed continuously on site. The influence of communication and distractions on SSI after surgery was assessed using logistic regressions, adjusting for risk factors. A total of 167 observed procedures were analysed; their mean(s.d.) duration was 4·6(2·1) h. A total of 24 SSIs (14·4 per cent) were diagnosed. Case-relevant communication during the procedure was independently associated with a reduced incidence of organ/space SSI (propensity score-adjusted odds ratio 0·86, 95 per cent c.i. 0·77 to 0·97; P = 0·014). Case-irrelevant communication during the closing phase of the procedure was independently associated with increased incidence of incisional SSI (propensity score-adjusted odds ratio 1·29, 1·08 to 1·55; P = 0·006). Distractions had no association with SSI. More case-relevant communication was associated with fewer organ/space SSIs, and more case-irrelevant communication during wound closure was associated with incisional SSI. © 2015 BJS Society Ltd Published by John Wiley & Sons Ltd.

Effect of a single prophylactic preoperative oral antibiotic dose on surgical site infection following complex dermatological procedures on the nose and ear: a prospective, randomised, controlled, double-blinded trial.

PubMed

Rosengren, Helena; Heal, Clare F; Buttner, Petra G

2018-04-19

There is limited published research studying the effect of antibiotic prophylaxis on surgical site infection (SSI) in dermatological surgery, and there is no consensus for its use in higher-risk cases. The objective of this study was to determine the effectiveness of a single oral preoperative 2 g dose of cephalexin in preventing SSI following flap and graft dermatological closures on the nose and ear. Prospective double-blinded, randomised, placebo-controlled trial testing for difference in infection rates. Primary care skin cancer clinics in North Queensland, Australia, were randomised to 2 g oral cephalexin or placebo 40-60 min prior to skin incision. 154 consecutive eligible patients booked for flap or graft closure following skin cancer excision on the ear and nose. 2 g dose of cephalexin administered 40-60 min prior to surgery. Overall 8/69 (11.6%) controls and 1/73 (1.4%) in the intervention group developed SSI (p=0.015; absolute SSI reduction 10.2%; number needed to treat (NNT) for benefit 9.8, 95% CI 5.5 to 45.5). In males, 7/44 controls and 0/33 in the intervention group developed SSI (p=0.018; absolute SSI reduction 15.9%; NNT for benefit 6.3, 95% CI 3.8 to 19.2). SSI was much lower in female controls (1/25) and antibiotic prophylaxis did not further reduce this (p=1.0). There was no difference between the study groups in adverse symptoms attributable to high-dose antibiotic administration (p=0.871). A single oral 2 g dose of cephalexin given before complex skin closure on the nose and ear reduced SSI. ANZCTR 365115; Post-results. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Choice of intravenous antibiotic prophylaxis for colorectal surgery does matter.

PubMed

Deierhoi, Rhiannon J; Dawes, Lillian G; Vick, Catherine; Itani, Kamal M F; Hawn, Mary T

2013-11-01

The Surgical Care Improvement Program endorses mandatory compliance with approved intravenous prophylactic antibiotics; however, oral antibiotics are optional. We hypothesized that surgical site infection (SSI) rates may vary depending on the choice of antibiotic prophylaxis. A retrospective cohort study of elective colorectal procedures using Veterans Affairs Surgical Quality Improvement Program (VASQIP) and SSI outcomes data was linked to the Office of Informatics and Analytics (OIA) and Pharmacy Benefits Management (PBM) antibiotic data from 2005 to 2009. Surgical site infection rates by type of IV antibiotic agent alone (IV) or in combination with oral antibiotic (IV + OA) were determined. Generalized estimating equations were used to examine the association between type of antibiotic prophylaxis and SSI for the entire cohort and stratified by use of oral antibiotics. After 5,750 elective colorectal procedures, 709 SSIs (12.3%) developed within 30 days. Oral antibiotic + IV (n = 2,426) had a lower SSI rate than IV alone (n = 3,324) (6.3% vs 16.7%, p < 0.0001). There was a significant difference in the SSI rate based on type of preoperative IV antibiotic given (p ≤ 0.0001). Generalized estimating equations adjusting for significant covariates of age, body mass index, procedure work relative value units, and operation duration demonstrated an independent protective effect of oral antibiotics (odds ratio [OR] 0.37, 95% CI 0.29 to 0.46), as well as increased rates of SSI associated with ampicillin/sulbactam (OR 2.21, 95% CI 1.37 to 3.56) and second generation cephalosporins (cefoxitin, OR 2.50, 95% CI 1.83 to 3.42; cefotetan, OR 2.70, 95% CI 1.72 to 4.22) when compared with first generation cephalosporin/metronidazole. The choice of IV antibiotic was related to the SSI rate; however, oral antibiotics were associated with reduced SSI rate for every antibiotic class. Published by Elsevier Inc.

Performance of statistical process control methods for regional surgical site infection surveillance: a 10-year multicentre pilot study.

PubMed

Baker, Arthur W; Haridy, Salah; Salem, Joseph; Ilieş, Iulian; Ergai, Awatef O; Samareh, Aven; Andrianas, Nicholas; Benneyan, James C; Sexton, Daniel J; Anderson, Deverick J

2017-11-24

Traditional strategies for surveillance of surgical site infections (SSI) have multiple limitations, including delayed and incomplete outbreak detection. Statistical process control (SPC) methods address these deficiencies by combining longitudinal analysis with graphical presentation of data. We performed a pilot study within a large network of community hospitals to evaluate performance of SPC methods for detecting SSI outbreaks. We applied conventional Shewhart and exponentially weighted moving average (EWMA) SPC charts to 10 previously investigated SSI outbreaks that occurred from 2003 to 2013. We compared the results of SPC surveillance to the results of traditional SSI surveillance methods. Then, we analysed the performance of modified SPC charts constructed with different outbreak detection rules, EWMA smoothing factors and baseline SSI rate calculations. Conventional Shewhart and EWMA SPC charts both detected 8 of the 10 SSI outbreaks analysed, in each case prior to the date of traditional detection. Among detected outbreaks, conventional Shewhart chart detection occurred a median of 12 months prior to outbreak onset and 22 months prior to traditional detection. Conventional EWMA chart detection occurred a median of 7 months prior to outbreak onset and 14 months prior to traditional detection. Modified Shewhart and EWMA charts additionally detected several outbreaks earlier than conventional SPC charts. Shewhart and SPC charts had low false-positive rates when used to analyse separate control hospital SSI data. Our findings illustrate the potential usefulness and feasibility of real-time SPC surveillance of SSI to rapidly identify outbreaks and improve patient safety. Further study is needed to optimise SPC chart selection and calculation, statistical outbreak detection rules and the process for reacting to signals of potential outbreaks. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Energy Dissipation in Earthquake Soil Structure Interaction: The September 3rd, 2016 M5.8 Pawnee Oklahoma Earthquake

NASA Astrophysics Data System (ADS)

Yang, H.; Sinha, S. K.; Feng, Y.; Jeremic, B.

2016-12-01

The M5.8 earthquake occurred in Pawnee, Oklahoma on September 3rd 2016 is the strongest seismic event recorded in Oklahoma. Soil structure interaction (SSI) played an important role in this tragic event. As a major aspect of SSI analysis, the propagation and dissipation of seismic energy will be studied in depth, with particular focus on the ground motion recorded in this earthquake. Seismic energy propagates from seismic source to the SSI system and is dissipated within and around the SSI system. Energy dissipation with the SSI system is related to inelastic behavior of soil, rock, contact zone (foundation-soil/rock), structural components and energy dissipators. Accurate evaluation of seismic energy can be used to optimize SSI system for safety and economy. The SSI system can be designed so that majority of seismic energy is dissipated within soil and soil-foundation contact zone, away from the structure.Accurate and theoretically sound modeling of propagation and dissipation is essential to use of seismic energy for design and assessment. The rate of plastic work is defined as the product of stress and the rate of plastic strain. On the other hand, plastic dissipation is defined as a form of heat transfer. The difference between these two quantities, which has been neglected in many studies, is a plastic part of the free energy. By considering energy storage and dissipation at both micro (particle) scale and macro (continuum) scale, it can be shown that the plastic free energy is an intrinsic attribute at the continuum scale due to particle rearrangement. Proper application of thermodynamics to finite element simulations, plastic dissipation can be correctly modeled. Examples will be used to illustrate above point on both constitutive, single element and SSI model scales. In addition, propagation of seismic energy, its dissipation (timing and location) will be used to illustrate use in design and assessment.

Operating Room Traffic as a Modifiable Risk Factor for Surgical Site Infection.

PubMed

Wanta, Brendan T; Glasgow, Amy E; Habermann, Elizabeth B; Kor, Daryl J; Cima, Robert R; Berbari, Elie F; Curry, Timothy B; Brown, Michael J; Hyder, Joseph A

2016-12-01

Surgical site infections (SSI) contribute to surgical patients' morbidity and costs. Operating room traffic may be a modifiable risk factor for SSI. We investigated the impact of additional operating room personnel on the risk of superficial SSI (sSSI). In this matched case-control study, cases included patients in whom sSSI developed in clean surgical incisions after elective, daytime operations. Control subjects were matched by age, gender, and procedure. Operating room personnel were classified as (1) surgical scrubbed, (2) surgical non-scrubbed, or (3) anesthesia. We used conditional logistic regression to test the extent to which additional personnel overall and from each work group were associated with infection. In total, 474 patients and 803 control subjects were identified. Each additional person among total personnel and personnel from each work group was significantly associated with greater odds of infection (all personnel, odds ratio [OR] = 1.082, 95% confidence interval [CI] 1.031-1.134, p = 0.0013; surgical scrubbed OR = 1.132, 95% CI 1.029-1.245, p = 0.0105; surgical non-scrubbed OR = 1.123, 95% CI 1.008-1.251, p = 0.0357; anesthesia OR = 1.153, 95% CI 1.031-1.290, p = 0.0127). After adjusting for operative duration, body mass index, diabetes mellitus, and vascular disease, additional personnel and sSSI were no longer associated overall or for any work groups (total personnel OR = 1.033, 95% CI 0.974-1.095, p = 0.2746; surgical scrubbed OR = 1.060, 95% CI 0.952-1.179, p = 0.2893; surgical non-scrubbed OR = 1.023 95% CI 0.907-1.154, p = 0.7129; anesthesia OR = 1.051, 95% CI 0.926-1.193, p = 0.4442). The presence of additional operating room personnel was not independently associated with increased odds of sSSI. Efforts dedicated to sSSI reduction should focus on other modifiable risk factors.

Ganymede’s stratigraphy and crater distributions in Voyager and Galileo SSI images: results from the anti-jovian hemisphere

NASA Astrophysics Data System (ADS)

Wagner, Roland Josef; Schmedemann, Nico; Stephan, Katrin; Werner, Stephanie; Ivanov, Boris A.; Roatsch, Thomas; Jaumann, Ralf; Palumbo, Pasquale

2017-10-01

Crater size distributions are a valuable tool in planetary stratigraphy to derive the sequence of geologic events. In this study, we extend our previous work [1] in Ganymede’s sub-jovian hemisphere to the anti-jovian hemisphere. For geologic mapping, the map by [2] is used as a reference. Our study provides groundwork for the upcoming imaging by the JANUS camera aboard ESA’s JUICE mission [3]. Voyager-2 images are reprocessed using a map scale of 700 m/pxl achieved for parts of the anti-jovian hemisphere. To obtain relative ages from crater frequencies, we apply an updated crater scaling law for cratering into icy targets in order to derive a crater production function for Ganymede [1]. Also, we adopt the Poisson timing analysis method discussed and implemented recently [4] to obtain relative (and absolute model) ages. Results are compared to those from the sub-jovian hemisphere [1] as well as to support and/or refine the global stratigraphic system by [2]. Further emphasis is placed on local target areas in the anti-jovian hemisphere imaged by Galileo SSI at regional map scales of 100 to 300 m/pxl in order to study local geologic effects and processes. These areas incorporate (1) dark and (2) light tectonized materials, and (3) impact crater materials including an area with numerous secondaries from ray crater Osiris. References: [1] Wagner R. et al. (2014), DPS meeting #46, abstract 418.09. [2] Collins G. et al. (2013), U.S.G.S. Sci. Inv. Map 3237. [3] Della Corte V. et al. (2014), Proc. SPIE 9143, doi:10.1117/12.2056353. [4] Michael G. et al. (2016), Icarus 277, 279-285.

Galileo SSI lunar observations: Copernican craters and soils

NASA Technical Reports Server (NTRS)

Mcewen, A. S.; Greeley, R.; Head, James W.; Pieters, C. M.; Fischer, E. M.; Johnson, T. V.; Neukum, G.

1993-01-01

The Galileo spacecraft completed its first Earth-Moon flyby (EMI) in December 1990 and its second flyby (EM2) in December 1992. Copernican-age craters are among the most prominent features seen in the SSI (Solid-State Imaging) multispectral images of the Moon. The interiors, rays, and continuous ejecta deposits of these youngest craters stand out as the brightest features in images of albedo and visible/1-micron color ratios (except where impact melts are abundant). Crater colors and albedos (away from impact melts) are correlated with their geologic emplacement ages as determined from counts of superposed craters; these age-color relations can be used to estimate the emplacement age (time since impact event) for many Copernican-age craters on the near and far sides of the Moon. The spectral reflectivities of lunar soils are controlled primarily by (1) soil maturity, resulting from the soil's cumulative age of exposure to the space environment; (2) steady-state horizontal and vertical mixing of fresh crystalline materials ; and (3) the mineralogy of the underlying bedrock or megaregolith. Improved understanding of items (1) and (2) above will improve our ability to interpret item (3), especially for the use of crater compositions as probes of crustal stratigraphy. We have examined the multispectral and superposed crater frequencies of large isolated craters, mostly of Eratosthenian and Copernican ages, to avoid complications due to (1) secondaries (as they affect superposed crater counts) and (2) spatially and temporally nonuniform regolith mixing from younger, large, and nearby impacts. Crater counts are available for 11 mare craters and 9 highlands craters within the region of the Moon imaged during EM1. The EM2 coverage provides multispectral data for 10 additional craters with superposed crater counts. Also, the EM2 data provide improved spatial resolution and signal-to-noise ratios over the western nearside.

Edwards AFB, California. Limited Surface Observations Climatic Summary (LISOCS). Parts A, C-F.

DTIC Science & Technology

1984-12-01

ORp AND OR HAIL OBS WITH FOG AND OR SLOWING N RWTHOS OO STOR.S SNO W ADO IHOS OOPDRIZZLE DRIZZLE SLEET FRECIF HAZE SAND TO VISION Gas . S_...S--I- ___ IF L1 A--- - - - - -- TOTAL NUMIEI OP OSSEIVATIONSS T USAFETAC 0-8-5,0L-A, pivoos rO),O.$ Or tRIS porno ARE oSsoLE’S

Topography and Volcanoes on Io (color)

NASA Technical Reports Server (NTRS)

1997-01-01

The images used to create this enhanced color composite of Io were acquired by NASA's Galileo spacecraft during its seventh orbit (G7) of Jupiter. Low sun angles near the terminator (day-night boundary near the left side of the image) offer lighting conditions which emphasize the topography or relief on the volcanic satellite. The topography appears very flat near the active volcanic centers such as Loki Patera (the large dark horse-shoe shaped feature near the terminator) while a variety of mountains and plateaus exist elsewhere. The big reddish-orange ring in the lower right is formed by material deposited from the eruption of Pele, Io's largest volcanic plume.

North is to the top of this picture which merges images obtained with the clear, red, green, and violet filters of the solid state imaging (CCD) system on NASA's Galileo spacecraft. The resolution is 6.1 kilometers per picture element. The images were taken on April 4th, 1997 at a range of 600,000 kilometers.

The Jet Propulsion Laboratory, Pasadena, CA manages the Galileo mission for NASA's Office of Space Science, Washington, DC. JPL is an operating division of California Institute of Technology (Caltech).

Concurrent results from Galileo's exploration of Io appear in the October 15th, 1997 issue of Geophysical Research Letters. The papers are: Temperature and Area Constraints of the South Volund Volcano on Io from the NIMS and SSI Instruments during the Galileo G1 Orbit, by A.G. Davies, A.S. McEwen, R. Lopes-Gautier, L. Keszthelyi, R.W. Carlson and W.D. Smythe. High-temperature hot spots on Io as seen by the Galileo Solid-State Imaging (SSI) experiment, by A. McEwen, D. Simonelli, D. Senske, K. Klassen, L. Keszthelyi, T. Johnson, P. Geissler, M. Carr, and M. Belton. Io: Galileo evidence for major variations in regolith properties, by D. Simonelli, J. Veverka, and A. McEwen.

This image and other images and data received from Galileo are posted on the World Wide Web, on the Galileo mission home page at URL http://galileo.jpl.nasa.gov. Background information and educational context for the images can be found at URL http://www.jpl.nasa.gov/galileo/sepo

Analysis of very-high-resolution Galileo images of Europa: Implications for small-scale structure and surface evolution

NASA Astrophysics Data System (ADS)

Leonard, E. J.; Pappalardo, R. T.; Yin, A.; Prockter, L. M.; Patthoff, D. A.

2014-12-01

The Galileo Solid State Imager (SSI) recorded nine very high-resolution frames (8 at 12 m/pixel and 1 at 6 m/pixel) during the E12 flyby of Europa in Dec. 1997. To understand the implications for the small-scale structure and evolution of Europa, we mosaicked these frames (observations 12ESMOTTLE01 and 02, incidence ≈18°, emission ≈77°) into their regional context (part of observation 11ESREGMAP01, 220 m/pixel, incidence ≈74°, emission ≈23°), despite their very different viewing and lighting conditions. We created a map of geological units based on morphology, structure, and albedo along with stereoscopic images where the frames overlapped. The highly diverse units range from: high albedo sub-parallel ridge and grooved terrain; to variegated-albedo hummocky terrain; to low albedo and relatively smooth terrain. We classified and analyzed the diverse units solely based on the high-resolution image mosaic, prior to comparison to the context image, to obtain an in-depth look at possible surface evolution and underlying formational processes. We infer that some of these units represent different stages and forms of resurfacing, including cryovolcanic and tectonic resurfacing. However, significant morphological variation among units in the region indicates that there are different degrees of resurfacing at work. We have created candidate morphological sequences that provide insight into the conversion of ridged plains to chaotic terrain—generally, a process of subduing formerly sharp features through tectonic modification and/or cryovolcanism. When the map of the high-resolution area is compared to the regional context, features that appear to be one unit at regional resolution are comprised of several distinct units at high resolution, and features that appear to be smooth in the context image are found to show distinct textures. Moreover, in the context image, transitions from ridged units to disrupted units appear to be gradual; however the high-resolution image reveals them to be abrupt, suggesting tectonic control of these boundaries. These discrepancies could have important implications for a future landed exploration.

A profile of children with disabilities receiving SSI: highlights from the National Survey of SSI Children and Families.

PubMed

Rupp, Kalman; Davies, Paul S; Newcomb, Chad; Iams, Howard; Becker, Carrie; Mulpuru, Shanti; Ressler, Stephen; Romig, Kathleen; Miller, Baylor

This article provides a nationally representative profile of noninstitutionalized children 0 to 17 years of age who were receiving support from the Supplemental Security Income (SSI) program because of a disability. To assess the role of the SSI program in providing assistance to low-income children with disabilities and their families, it is important to obtain detailed information on demographic characteristics, income and assets, health and disabilities, and health care utilization. Yet administrative records of the Social Security Administration do not contain many of the relevant data items, and the records provide only an incomplete picture of the family relationships affecting the lives of children with disabilities. The National Survey of SSI Children and Families fills this gap. This summary article is based on survey interviews conducted between July 2001 and June 2002 and provides some highlights characterizing children with disabilities who were receiving SSI and their families. Most children receiving SSI (hereafter referred to as "SSI children") lived in a family headed by a single mother, and less than one in three lived with both parents. A very high proportion, about half, were living in a household with at least one other individual reported to have had a disability. About 70 percent of children received some kind of special education. SSI support was the most important source of family income, with earnings a close second. On average, SSI payments accounted for nearly half of the income for the children's families, and earnings accounted for almost 40 percent. When all sources of family income were considered, slightly more than half (54 percent) of SSI children lived in families above the poverty threshold, a notable fact given that the federal SSI program guarantees only a subpoverty level of income. However, beyond these averages there was substantial variation, with some children living in families with income well below the poverty threshold and others having income well over 200 percent of the poverty threshold. About one-third of SSI children lived in families owning a home, two-thirds lived with parents or guardians with at least one car, and about 40 percent lived with parents or guardians with zero liquid assets. Less than 4 percent lived with adults who owned stocks, mutual funds, notes, certificates of deposit, or savings bonds. The Social Security Administration's administrative records contain only a limited amount of information about disability diagnoses. The National Survey of SSI Children and Families supplements those records with data from an array of questions on functional limitations, self-reported health, and the perceived severity of disabilities. The data suggest that a great degree of variation in severity exists within the childhood caseload, as reflected in reports of the presence or absence of six functional limitations, perceived overall health status, and perceived impact of disability on the child's ability to do things. Overall, 36 percent of the children were reported to have had disabilities that affected their abilities to do things "a great deal," and for 21 percent their difficulties had very little or no impact. Physical disabilities were most common among children aged 0 to 5, and mental disabilities dominated the picture for the other two age groups: 6 to 12 and 13 to 17. Virtually all SSI children are covered by some form of health insurance, with Medicaid being by far the most common source of health insurance coverage. Just as in the case of the severity of disabilities, substantial variation was reported in health care utilization among SSI children. Almost 30 percent of children had two or fewer doctor visits during the 12 months preceding the interview, and close to 50 percent had five or more doctor visits. About four-fifths of the children had no reported hospitalizations or surgeries during the previous year. More than 40 percent of the children visited an emergency room during the previous year, most of them more than once. Importantly, no out-of-pocket costs associated with medical care were reported for more than two-thirds of the children, and only about 3 percent had annual expenses exceeding $1,000 for physical and mental health care. This finding suggests that SSI payments are not used to cover medical expenses for the overwhelming majority of children. The use of supportive therapies varied widely among SSI children: more than half reported having used physical, occupational, or speech therapy; only 8 percent used respite care for the parents or other family members. An analysis of the perception of the survey respondents shows that more than one-third of children had unmet needs for mental health counseling services, and about three-quarters of families had unmet needs for respite care. In several service categories, the proportion perceived to have had unmet service needs was around 10 percent or less. In the dominant service category of physical, occupational, and speech therapy, only 11 percent perceived to have had unmet service needs.

Incidence and Risk Factors for Health-Care Associated Infections after Hip Operation.

PubMed

Hessels, Amanda J; Agarwal, Mansi; Liu, Jianfang; Larson, Elaine L

2016-12-01

Hip operation reduces pain and improves mobility and quality of life for more than 300,000 people annually, most of whom are more than 65 years old. Substantial increases in surgical volume are projected between 2005 and 2030 in primary total (174%) and revision (137%) procedures. This projection demands that the impact of increasing age on the relative risk of health-care associated infections (HAI) after hip surgical procedures be assessed. Our aim was to examine the incidence and risk factors of HAI among patients who underwent hip operations between 2006 and 2012. This secondary analysis included data from patients 18 years old or older and having a hip prosthesis procedure in three New York City hospitals between 2006 and 2012. Procedures were categorized as total or partial hip replacements or revision and re-surfacing procedures. Outcomes of interest were blood stream infections (BSI), urinary tract infections (UTI), or surgical site infections (SSI). Patients in whom an infection developed during the hospital visit in which the hip procedure occurred were counted as cases. Of 2021 patients, approximately 11% (n = 218) had an HAI. There was no difference in infection rates by admission year despite an increase in surgical volume. SSI was associated with younger age, previous hospitalization, and hip revision surgical procedure whereas UTI and BSI were associated with older age, greater co-morbidity, longer pre-operative length of stay and intensive care unit stay, (p < 0.05). HAI after hip operation affected approximately one in 10 patients over a 7-year period in three high-volume hospitals. SSI occurred least frequently, predominantly among patients who underwent revision surgery (without previous SSI), were younger, and had a history of previous hospitalization. Infections such as BSI and UTI, although rare, occurred more frequently and in patients with more co-morbidities, longer pre-operative length of stay, and who required higher level care. Further research to understand these unexpected findings and target interventions is warranted.

Solar Spectral Irradiance Variability of Some Chromospheric Emission Lines Through the Solar Activity Cycles 21-23

NASA Astrophysics Data System (ADS)

Göker, Ü. D.; Gigolashvili, M. Sh.; Kapanadze, N.

2017-06-01

A study of variations of solar spectral irradiance (SSI) in the wavelength ranges 121.5 nm-300.5 nm for the period 1981-2009 is presented. We used various data for ultraviolet (UV) spectral lines and international sunspot number (ISSN) from interactive data centers such as SME (NSSDC), UARS (GDAAC), SORCE (LISIRD) and SIDC, respectively. We reduced these data by using the MATLAB software package. In this respect, we revealed negative correlations of intensities of UV (289.5 nm-300.5 nm) spectral lines originating in the solar chromosphere with the ISSN index during the unusually prolonged minimum between the solar activity cycles (SACs) 23 and 24. We also compared our results with the variations of solar activity indices obtained by the ground-based telescopes. Therefore, we found that plage regions decrease while facular areas are increasing in SAC 23. However, the decrease in plage regions is seen in small sunspot groups (SGs), contrary to this, these regions in large SGs are comparable to previous SACs or even larger as is also seen in facular areas. Nevertheless, negative correlations between ISSN and SSI data indicate that these variations are in close connection with the classes of sunspots/SGs, faculae and plage regions. Finally, we applied the time series analysis of spectral lines corresponding to the wavelengths 121.5 nm-300.5 nm and made comparisons with the ISSN data. We found an unexpected increase in the 298.5 nm line for the Fe II ion. The variability of Fe II ion 298.5 nm line is in close connection with the facular areas and plage regions, and the sizes of these solar surface indices play an important role for the SSI variability, as well. So, we compared the connection between the sizes of faculae and plage regions, sunspots/SGs, chemical elements and SSI variability. Our future work will be the theoretical study of this connection and developing of a corresponding model.

Controlled photomosaic map of Callisto JC 15M CMN

USGS Publications Warehouse

,

2002-01-01

This sheet is one in a series of maps of the Galilean satellites of Jupiter at a nominal scale of 1:15,000,000. This series is based on data from the Galileo Orbiter Solid-State Imaging (SSI) camera and the cameras of the Voyager 1 and 2 spacecraft. Mercator and Polar Stereographic projections used for this map of Callisto are based on a sphere having a radius of 2,409.3 km. The scale is 1:8,388,000 at ±56° latitude for both projections. Longitude increases to the west in accordance with the International Astronomical Union (1971) (Seidelmann and others, 2002). The geometric control network was computed at the RAND Corporation using RAND's most recent solution as of April 1999 (Davies and Katayama, 1981; Davies and others, 1998). This process involved selecting control points on the individual images, making pixel measurements of their locations, using reseau locations to correct for geometric distortions, and converting the measurements to millimeters in the focal plane. These data are combined with the camera focal lengths and navigation solutions as input to photogrammetric triangulation software that solves for the best-fit sphere, the coordinates of the control points, the three orientation angles of the camera at each exposure (right ascension, declination, and twist), and an angle (W0) which defines the orientation of Callisto in space. W0-in this solution 259.51°-is the angle along the equator to the east, between the 0° meridian and the equator's intersection with the celestial equator at the standard epoch J2000.0. This solution places the crater Saga at its defined longitude of 326° west (Seidelmann and others, 2002). This global map base uses the best image quality and moderate resolution coverage supplied by Galileo SSI and Voyager 1 and 2 (Batson, 1987; Becker and others, 1998; Becker and others, 1999; Becker and others, 2001). The digital map was produced using Integrated Software for Imagers and Spectrometers (ISIS) (Eliason, 1997; Gaddis and others, 1997; Torson and Becker, 1997). The individual images were radiometrically calibrated and photometrically normalized using a Lunar-Lambert function with empirically derived values (McEwen, 1991; Kirk and others, 2000). A linear correction based on the statistics of all overlapping areas was then applied to minimize image brightness variations. The image data were selected on the basis of overall image quality, reasonable original input resolution (from 20 km/pixel for gap fill to as much as 150 m/pixel), and availability of moderate emission/incidence angles for topography. Although consistency was achieved where possible, different filters were included for global image coverage as necessary: clear for Voyager 1 and 2; clear and green (559 nm) for Galileo SSI. Individual images were projected to a Sinusoidal Equal-Area projection at an image resolution of 1.0 kilometer/pixel. The final constructed Sinusoidal projection mosaic was then reprojected to the Mercator and Polar Stereographic projections included on this sheet. The final mosaic was enhanced using commercial software. Names on this sheet are approved by the International Astronomical Union. Names have been applied for features clearly visible at the scale of this map; for a complete list of nomenclature for Callisto, please see the Gazeteer of Planetary Nomenclature. Font color was chosen only for readability.

Solar Spectral Irradiance Changes During Cycle 24

NASA Technical Reports Server (NTRS)

Marchenko, Sergey; Deland, Matthew

2014-01-01

We use solar spectra obtained by the Ozone Monitoring Instrument (OMI) on board the Aura satellite to detect and follow long-term (years) and short-term (weeks) changes in the solar spectral irradiance (SSI) in the 265-500 nm spectral range. During solar Cycle 24, in the relatively line-free regions the SSI changed by approximately 0.6% +/- 0.2% around 265 nm. These changes gradually diminish to 0.15% +/- 0.20% at 500 nm. All strong spectral lines and blends, with the notable exception of the upper Balmer lines, vary in unison with the solar "continuum." Besides the lines with strong chromospheric components, the most involved species include Fe I blends and all prominent CH, NH, and CN spectral bands. Following the general trend seen in the solar "continuum," the variability of spectral lines also decreases toward longer wavelengths. The long-term solar cycle SSI changes are closely, to within the quoted 0.1%-0.2% uncertainties, matched by the appropriately adjusted short-term SSI variations derived from the 27 day rotational modulation cycles. This further strengthens and broadens the prevailing notion about the general scalability of the UV SSI variability to the emissivity changes in the Mg II 280 nm doublet on timescales from weeks to years. We also detect subtle deviations from this general rule: the prominent spectral lines and blends at lambda approximately or greater than 350 nm show slightly more pronounced 27 day SSI changes when compared to the long-term (years) trends. We merge the solar data from Cycle 21 with the current Cycle 24 OMI and GOME-2 observations and provide normalized SSI variations for the 170-795 nm spectral region.

Postoperative urinary tract infection and surgical site infection in instrumented spinal surgery: is there a link?

PubMed

Núñez-Pereira, S; Rodríguez-Pardo, D; Pellisé, F; Pigrau, C; Bagó, J; Villanueva, C; Cáceres, E

2014-08-01

A potential relationship between postoperative urinary tract infection (UTI) and surgical site infection (SSI) following posterior spinal fusion and instrumentation (PSFI) was investigated. A retrospective review was performed of prospectively collected demographic, clinical and microbiological data of 466 consecutive patients (median age, 53.7 years (interquartile range (IQR) 33.8-65.6); 58.6% women) undergoing PSFI to identify those with UTI in the first 4 weeks and SSI in the first 12 weeks after PSFI. Overall, 40.8% had an American Society of Anesthesiologists score of >2, and 49.8% had undergone fusion of more than three segments. Eighty-nine patients had UTI, 54 had SSI, and 22 had both conditions. In nine of the 22 (38%) cases, the two infections were caused by the same microorganism. The urinary tract was the probable source of SSI by Gram-negative bacteria in 38% (8/21) of cases. On multivariate analysis, UTI (OR 3.1, 95% CI 1.6-6.1; P 0.001) and instrumentation of more than three segments (OR 2.7, 95% CI 1.1-6.3; P 0.024) were statistically associated with SSI. Patients receiving ciprofloxacin for UTI had higher microbial resistance rates to fluoroquinolones at SSIs (46.13%) than those without ciprofloxacin (21.9%), although the difference did not reach statistical significance (p 0.1). In our series, UTI was significantly associated with SSI after PSFI. On the basis of our results, we conclude that further efforts to reduce the incidence of postoperative UTI and provide adequate empirical antibiotic therapy that avoids quinolones whenever possible may help to reduce SSI rates and potential microbial resistance. © 2014 The Authors Clinical Microbiology and Infection © 2014 European Society of Clinical Microbiology and Infectious Diseases.

Single versus double blade technique for skin incision and deep dissection in surgery for closed fracture: a prospective randomised control study.

PubMed

Trikha, V; Saini, P; Mathur, P; Agarwal, A; Kumar, S V; Choudhary, B

2016-04-01

To compare blade cultures in surgery for closed fracture using a single or double blade technique to determine whether the current practice of double blade technique is justified. 155 men and 29 women aged 20 to 60 (mean, 35) years who underwent surgery for closed fracture with healthy skin at the incision site were included. Patients were block randomised to the single (n=92) or double (n=92) blade technique. Blades were sent for bacteriological analysis. Outcome measures were early surgical site infection (SSI) within 30 days and cultures from the blades. The 2 groups were comparable in baseline characteristics. In the single blade group, 6 surgical blades and 2 control blades showed positive cultures; 4 patients developed SSI, but only one had a positive culture from the surgical blade (with different organism isolated from the wound culture). In the double blade group, 6 skin blades, 7 deep blades, and 0 control blade showed positive culture; only 2 patients had the same bacteria grown from both skin and deep blade. Five patients developed SSI, but only one patient had a positive culture from the deep blade (with different organism isolated from the wound culture). The difference in incidence of culture-positive blade or SSI between the 2 groups was not significant. The relative risk of SSI in the single blade group was 0.8. Positive blade culture was not associated with SSI in the single or double blade group. The practice of changing blade following skin incision has no effect on reducing early SSI in surgery for closed fracture in healthy patients with healthy skin.

Ketamine versus midazolam in bipolar depression with suicidal thoughts: A pilot midazolam-controlled randomized clinical trial.

PubMed

Grunebaum, Michael F; Ellis, Steven P; Keilp, John G; Moitra, Vivek K; Cooper, Thomas B; Marver, Julia E; Burke, Ainsley K; Milak, Matthew S; Sublette, M Elizabeth; Oquendo, Maria A; Mann, J John

2017-05-01

To evaluate feasibility and effects of a sub-anesthetic infusion dose of ketamine versus midazolam on suicidal ideation in bipolar depression. Neurocognitive, blood and saliva biomarkers were explored. Sixteen participants with bipolar depression and a Scale for Suicidal Ideation (SSI) score of ≥4 were randomized to ketamine (0.5 mg/kg) or midazolam (0.02 mg/kg). Current pharmacotherapy was maintained excluding benzodiazepines within 24 hours. The primary clinical outcome was SSI score on day 1 post-infusion. Results supported feasibility. Mean reduction of SSI after ketamine infusion was almost 6 points greater than after midazolam, although this was not statistically significant (estimate=5.84, SE=3.01, t=1.94, P=.074, 95% confidence interval ([CI)]=-0.65 to 12.31). The number needed to treat for response (SSI <4 and at least 50% below baseline) was 2.2, and for remission (SSI=0) was 3.2. The strongest neurocognitive correlation was between memory improvement on the Selective Reminding Test (SRT) and reduction in SSI score on day 1 after ketamine (ρ=-.89, P=.007). Pre- to post-infusion decrease in serum brain derived neurotrophic factor (BDNF) correlated with reduction in SSI from baseline to day 1 after ketamine (n=5, ρ=0.90, P=.037) but not midazolam (P=.087). The study demonstrated feasibility. Suicidal thoughts were lower after ketamine than after midazolam at a trend level of significance, likely due to the small pilot sample. Memory improvement and BDNF are promising biomarkers. Replication is needed in an adequately powered full-scale trial. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Surgical site infection: an observer-blind, randomized trial comparing electrocautery and conventional scalpel.

PubMed

Rongetti, Regiane Ladislau; Oliveira e Castro, Paulo de Tarso; Vieira, Renê Aloisio da Costa; Serrano, Sérgio Vicente; Mengatto, Mariana Fabro; Fregnani, José Humberto Tavares Guerreiro

2014-01-01

To evaluate the incidence of surgical site infection (SSI) based on the type of scalpel used for incisions in the skin and in subcutaneous tissues. Observer-blind, randomized equivalence clinical trial with two arms (electrocautery versus conventional scalpel) which evaluated 133 women undergoing elective abdominal gynecologic oncology surgery. A simple randomization stratified by body mass index (BMI: 30 kg/m(2)) was carried out. Women were evaluated at 14 and 30 days following the operation. A multivariate analysis was performed in order to check whether the type of scalpel would be a risk factor for SSI. Group arms were balanced for all variables, excepted for surgical time, which was significantly higher in the electrocautery group (mean: 161.1 versus 203.5 min, P = 0.029). The rates of SSI were 7.4% and 9.7%, respectively, for the conventional scalpel and electrocautery groups (P = 0.756). The exploratory multivariate model identified body mass index ≥30 kg/m(2) (OR = 24.2, 95% CI: 2.8-212.1) and transverse surgical incision (OR = 8.1, 95% CI: 1.5-42.6) as independent risk factors for SSI. The type of scalpel used in surgery, when adjusted for these variables and the surgery time, was not a risk factor for SSI. This study showed that the SSI rates for conventional scalpel and electrocautery were not significantly different. These results were consistent with others reported in the literature and would not allow a surgeon to justify scalpel choice based on SSI. NCT01410175 (Clinical Trials - NIH). Copyright © 2014 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

Failure to Redose Antibiotic Prophylaxis in Long Surgery Increases Risk of Surgical Site Infection.

PubMed

Kasatpibal, Nongyao; Whitney, Joanne D; Dellinger, E Patchen; Nair, Bala G; Pike, Kenneth C

Antibiotic prophylaxis is a key component of the prevention of surgical site infection (SSI). Failure to manage antibiotic prophylaxis effectively may increase the risk of SSI. This study aimed to examine the effects of antibiotic prophylaxis on SSI risk. A retrospective cohort study was conducted among patients having general surgery between May 2012 and June 2015 at the University of Washington Medical Center. Peri-operative data extracted from hospital databases included patient and operation characteristics, intra-operative medication and fluid administration, and survival outcome. The effects of antibiotic prophylaxis and potential factors on SSI risk were estimated using multiple logistic regression and were expressed as risk ratios (RRs). A total of 4,078 patients were eligible for analysis. Of these, 180 had an SSI. Mortality rates within and after 30 days were 0.8% and 0.3%, respectively. Improper antibiotic redosing increased the risk of SSI (RR 4.61; 95% confidence interval [CI] 1.33-15.91). Other risk factors were in-patient status (RR 4.05; 95% CI 1.69-9.66), smoking (RR 1.63; 95% CI 1.03-2.55), emergency surgery (RR 1.97; 95% CI 1.26-3.08), colectomy (RR 3.31; 95% CI 1.19-9.23), pancreatectomy (RR 4.52; 95% CI 1.53-13.39), proctectomy (RR 5.02; 95% CI 1.72-14.67), small bowel surgery (RR 6.16; 95% CI 2.13-17.79), intra-operative blood transfusion >500 mL (RR 2.76; 95% CI 1.45-5.26), and multiple procedures (RR 1.40; 95% CI 1.01-1.95). These data demonstrate that failure to redose prophylactic antibiotic during long operations increases the risk of SSI. Strengthening a collaborative surgical quality improvement program may help to eradicate this risk.

Past history of skin infection and risk of surgical site infection after elective surgery.

PubMed

Faraday, Nauder; Rock, Peter; Lin, Elaina E; Perl, Trish M; Carroll, Karen; Stierer, Tracey; Robarts, Polly; McFillin, Angela; Ross, Tracy; Shah, Ashish S; Riley, Lee H; Tamargo, Rafael J; Black, James H; Blasco-Colmenares, Elena; Guallar, Eliseo

2013-01-01

To identify baseline patient characteristics associated with increased susceptibility to surgical site infection (SSI) after elective surgery. The Center for Medicare and Medicaid Services considers SSI to be preventable through adherence to current infection control practices; however, the etiology of wound infection is incompletely understood. Prospective cohort study involving patients undergoing cardiac, vascular, craniotomy, and spinal surgery at 2 academic medical centers in Baltimore, MD. A comprehensive medical history was obtained at baseline, and participants were followed for 6 months using active inpatient and outpatient surveillance for deep SSI and infectious death. Infection control best practices were monitored perioperatively. The relative risk of SSI/infectious death was determined comparing those with versus those without a past medical history of skin infection using Cox proportional hazards models. Of 613 patients (mean [SD] = 62.3 [11.5] years; 42.1% women), 22.0% reported a history of skin infection. The cumulative incidence of deep SSI/infectious death was 6.7% versus 3.1% for those with and without a history of skin infection, respectively (unadjusted hazard ratio (HR) = 2.25; 95% confidence interval (95% CI), 0.98-5.14; P = 0.055). Risk estimates increased after adjustments for demographic and socioeconomic variables (HR = 2.82; 95% CI, 1.18-6.74; P = 0.019) and after propensity score adjustment for all potential confounders (HR = 3.41; 95% CI, 1.36-8.59; P = 0.009). Adjustments for intraoperative infection risk factors and adherence to infection control best practice metrics had no impact on risk estimates. A history of skin infection identified a state of enhanced susceptibility to SSI at baseline that is independent of traditional SSI risk factors and adherence to current infection control practices.

The Association Between Operating Room Personnel and Turnover With Surgical Site Infection in More Than 12 000 Neurosurgical Cases.

PubMed

Wathen, Connor; Kshettry, Varun R; Krishnaney, Ajit; Gordon, Steven M; Fraser, Thomas; Benzel, Edward C; Modic, Michael T; Butler, Sam; Machado, Andre G

2016-12-01

Surgical site infection (SSI) contributes significantly to postoperative morbidity and mortality and greatly increases the cost of care. To identify the impact of workflow and personnel-related risk factors contributing to the incidence of SSIs in a large sample of neurological surgeries. Data were obtained using an enterprisewide electronic health record system, operating room, and anesthesia records for neurological procedures conducted between January 1, 2009, and November 30, 2012. SSI data were obtained from prospective surveillance by infection preventionists using Centers for Disease Control and Prevention definitions. A multivariate model was constructed and refined using backward elimination logistic regression methods. The analysis included 12 528 procedures. Most cases were elective (94.5%), and the average procedure length was 4.8 hours. The average number of people present in the operating room at any time during the procedure was 10.0. The overall infection rate was 2.3%. Patient body mass index (odds ratio, 1.03; 95% confidence interval [CI], 1.01-1.04) and sex (odds ratio, 1.36; 95% CI, 1.07-1.72) as well as procedure length (odds ratio, 1.19 per additional hour; 95% CI, 1.15-1.23) and nursing staff turnovers (odds ratio, 1.095 per additional turnover; 95% CI, 1.02-1.21) were significantly correlated with the risk of SSI. This study found that patient body mass index and male sex were associated with an increased risk of SSI. Operating room personnel turnover, a modifiable, work flow-related factor, was an independent variable positively correlated with SSI. This study suggests that efforts to reduce operating room turnover may be effective in preventing SSI. OR, operating roomSSI, surgical site infection.

A longitudinal evaluation of the effect of Medi-Cal managed care on supplemental security income and aid to families with dependent children enrollees in two California counties.

PubMed

Lo Sasso, A T; Freund, D A

2000-09-01

We examined the differential effect of Medicaid managed care (MMC) among Aid to Families With Dependent Children (AFDC) and Supplemental Security Income (SSI) enrollees over time by comparing the experiences of adult nonelderly enrollees in the Health Plan of San Mateo in California versus Ventura County's fee-for-service (FFS) enrollees. Four years of administrative claims data were used to construct a longitudinal data set and estimate panel data models to decompose the effect of managed care over time. AFDC MMC enrollees exhibited generally fewer ambulatory visits, lower expenditures, and higher monthly probabilities of a preventable hospitalization relative to comparably enrolled FFS patients. SSI MMC enrollees had more emergency department visits and higher monthly probabilities of hospitalization. However, SSI MMC enrollees had more ambulatory visits and more medications during the first year of enrollment relative to SSI FFS enrollees, although levels were similar in subsequent years. SSI MMC enrollees did not exhibit a significantly higher level of expenditures in the first year of enrollment, although in subsequent years, expenditure levels were significantly lower. The results for emergency department visits and preventable hospitalizations presented a decidedly downbeat picture of access to care for AFDC and SSI enrollees in MMC. However, some aspects of utilization under managed care exhibited results consistent with long-term- oriented treatment for enrollees with a greater likelihood of remaining in the system for a longer period of time (SSI enrollees). By contrast, enrollees more likely to be enrolled for shorter periods (AFDC enrollees) tended to exhibit care patterns under MMC consistent with lower levels of care relative to FFS.

University Students' Knowledge Structures and Informal Reasoning on the Use of Genetically Modified Foods: Multidimensional Analyses

NASA Astrophysics Data System (ADS)

Wu, Ying-Tien

2013-10-01

This study aims to provide insights into the role of learners' knowledge structures about a socio-scientific issue (SSI) in their informal reasoning on the issue. A total of 42 non-science major university students' knowledge structures and informal reasoning were assessed with multidimensional analyses. With both qualitative and quantitative analyses, this study revealed that those students with more extended and better-organized knowledge structures, as well as those who more frequently used higher-order information processing modes, were more oriented towards achieving a higher-level informal reasoning quality. The regression analyses further showed that the "richness" of the students' knowledge structures explained 25 % of the variation in their rebuttal construction, an important indicator of reasoning quality, indicating the significance of the role of students' sophisticated knowledge structure in SSI reasoning. Besides, this study also provides some initial evidence for the significant role of the "core" concept within one's knowledge structure in one's SSI reasoning. The findings in this study suggest that, in SSI-based instruction, science instructors should try to identify students' core concepts within their prior knowledge regarding the SSI, and then they should try to guide students to construct and structure relevant concepts or ideas regarding the SSI based on their core concepts. Thus, students could obtain extended and well-organized knowledge structures, which would then help them achieve better learning transfer in dealing with SSIs.

A Soil Service Index: Potential Soil Services to Society under Scenarios of Human Land Use and Population Growth

NASA Astrophysics Data System (ADS)

Hugelius, G.; Ahlström, A.; Loisel, J.; Harden, J. W.

2017-12-01

Soils provide numerous and indispensable services to ecological systems and human societies. As human populations and human land use changes, the capacity of soils to maintain these services may also change. To investigate this we provide the first global scale study based on the soil service index (SSI; see presentations by Harden et al. and Loisel et al. in this session for more details). In this index multiple soil services are numerically or quantitatively assessed, normalized to a unit-less scale for purposes of intercomparability. Soil services assessed under the SSI include organic matter and/or organic carbon storage; plant productivity; CO2 or GHG exchange with the atmosphere; water storage capacity; and nutrient storage and/or availability. The SSI may be applied at any scale. Here we present a first global application of the SSI and provide broad-scale analyses of soil service spatial distributions. We assess how the SSI will change under projected changes in human societies populations and human land use (following representative concentration pathway scenarios). Present and future potential utilization and vulnerability of soil resources are analyzed in the context of human population distributions and its projected changes. The SSI is designed to be broadly useful across scientific, governance and resource management organizations. To exemplify this, the parameterization of this is global soil service estimate is based on only open source input data.

PubMed Central

SPAGNOLO, A.M.; OTTRIA, G.; AMICIZIA, D.; PERDELLI, F.

2013-01-01

Summary Surgical site infections (SSI) account for 14% to 17% of all hospital-acquired infections and 38% of nosocomial infections in surgical patients. SSI remain a substantial cause of morbidity and death, possibly because of the larger numbers of elderly surgical patients or those with a variety of chronic and immunocompromising conditions, and emergence of antibiotic-resistant microorganisms. Factors causing surgical site infection are multifarious. Several studies have identified the main patient-related (endogenous risk factors) and procedure-related (external risk factors) factors that influence the risk of SSI. The rate of surgical wound infections is strongly influenced by operating theatre quality, too. A safe and salubrious operating theatre is an environment in which all sources of pollution and any micro-environmental alterations are kept strictly under control. This can be achieved only through careful planning, maintenance and periodic checks, as well as proper ongoing training for staff. Many international scientific societies have produced guidelines regarding the environmental features of operating theatres (positive pressure, exchanges of filtered air per hour, air-conditioning systems with HEPA filters, etc.) and issued recommendations on healthcare-associated infection, including SSI, concerning surveillance methods, intervention to actively prevent SSI and approaches to monitoring the implementation of such strategies. Therefore, the prevention of SSI requires a multidisciplinary approach and the commitment of all concerned, including that of those who are responsible for the design, layout and functioning of operating theatres. PMID:24783890

Procedure-specific Surgical Site Infection Incidence Varies Widely within Certain National Healthcare Safety Network Surgery Groups

PubMed Central

Saeed, Mohammed J; Dubberke, Erik R; Fraser, Victoria J; Olsen, Margaret A

2015-01-01

Background The National Healthcare Safety Network (NHSN) classifies surgical procedures into 40 categories. The objective of this study was to determine surgical site infection (SSI) incidence for clinically defined subgroups within 5 heterogeneous NHSN surgery categories. Methods This is a retrospective cohort study using the longitudinal State Inpatient Database. We identified 5 groups of surgical procedures (amputation; biliary, liver and pancreas [BILI]; breast; colon and hernia) using ICD-9-CM procedure codes in community hospitals in California, Florida and New York from January 2009 through September 2011 in persons aged ≥18 years. Each of these 5 categories was classified to more specific surgical procedures within the group. 90-day SSI rates were calculated using ICD-9-CM diagnosis codes. Results There were 62,901 amputation, 33,358 BILI, 72,058 breast, 125,689 colon and 85,745 hernia surgeries in 349,298 people. 90-day SSI rates varied significantly within each of the 5 subgroups. Within the BILI category, bile duct, pancreas and laparoscopic liver procedures had SSI rates of 7.2%, 17.2%, and 2.2%, respectively (p<0.0001 for each) compared to open liver procedures (11.1% SSI). Conclusion 90-day SSI rates varied widely within certain NHSN categories. Risk adjustment for specific surgery type is needed in order to make valid comparisons between hospitals. PMID:25818024

A novel approach to leveraging electronic health record data to enhance pediatric surgical quality improvement bundle process compliance.

PubMed

Fisher, Jason C; Godfried, David H; Lighter-Fisher, Jennifer; Pratko, Joseph; Sheldon, Mary Ellen; Diago, Thelma; Kuenzler, Keith A; Tomita, Sandra S; Ginsburg, Howard B

2016-06-01

Quality improvement (QI) bundles have been widely adopted to reduce surgical site infections (SSI). Improvement science suggests when organizations achieve high-reliability to QI processes, outcomes dramatically improve. However, measuring QI process compliance is poorly supported by electronic health record (EHR) systems. We developed a custom EHR tool to facilitate capture of process data for SSI prevention with the aim of increasing bundle compliance and reducing adverse events. Ten SSI prevention bundle processes were linked to EHR data elements that were then aggregated into a snapshot display superimposed on weekly case-log reports. The data aggregation and user interface facilitated efficient review of all SSI bundle elements, providing an exact bundle compliance rate without random sampling or chart review. Nine months after implementation of our custom EHR tool, we observed centerline shifts in median SSI bundle compliance (46% to 72%). Additionally, as predicted by high reliability principles, we began to see a trend toward improvement in SSI rates (1.68 to 0.87 per 100 operations), but a discrete centerline shift was not detected. Simple informatics solutions can facilitate extraction of QI process data from the EHR without relying on adjunctive systems. Analyses of these data may drive reductions in adverse events. Pediatric surgical departments should consider leveraging the EHR to enhance bundle compliance as they implement QI strategies. Copyright © 2016 Elsevier Inc. All rights reserved.

[Incidence of surgical site infection in ambulatory surgery: results of the INCISCO surveillance network in 1999-2000].

PubMed

Sewonou, A; Rioux, C; Golliot, F; Richard, L; Massault, P P; Johanet, H; Cherbonnel, G; Botherel, A H; Farret, D; Astagneau, P

2002-04-01

To estimate the incidence of surgical-site infections (SSI) in ambulatory surgery and to identify risk factors based on the surveillance network INCISO in 1999-2000. Annually, during a three-month period, each surgical ward had to include 200 consecutive operations. Patients were surveyed over the month following surgery. For each patient, data including peri-operative factors, type of procedure and SSI occurrence were collected on a standardized form by a surgical staff committed for the study. Of the 5,183 patients who underwent an ambulatory surgery, the SSI incidence ratio was 0.4% (95% CI [0.3-0.7]). Orthopedic, gynecologic/obstetrics, head and neck, skin and soft tissues surgery accounted for 83% of all ambulatory procedures. 93% of patients belonged to the 0 risk category of the National Nosocomial Infections Surveillance system (NNIS) index. Emergency, age, american anesthesia risk score (ASA), Altemeier wound class, and procedure duration were not found to be risk factors for SSI in ambulatory surgery. Based on these surveillance data, infectious risk was low in ambulatory surgery and was not associated with known SSI risk factors.

On the intrinsic timescales of temporal variability in measurements of the surface solar radiation

NASA Astrophysics Data System (ADS)

Bengulescu, Marc; Blanc, Philippe; Wald, Lucien

2018-01-01

This study is concerned with the intrinsic temporal scales of the variability in the surface solar irradiance (SSI). The data consist of decennial time series of daily means of the SSI obtained from high-quality measurements of the broadband solar radiation impinging on a horizontal plane at ground level, issued from different Baseline Surface Radiation Network (BSRN) ground stations around the world. First, embedded oscillations sorted in terms of increasing timescales of the data are extracted by empirical mode decomposition (EMD). Next, Hilbert spectral analysis is applied to obtain an amplitude-modulation-frequency-modulation (AM-FM) representation of the data. The time-varying nature of the characteristic timescales of variability, along with the variations in the signal intensity, are thus revealed. A novel, adaptive null hypothesis based on the general statistical characteristics of noise is employed in order to discriminate between the different features of the data, those that have a deterministic origin and those being realizations of various stochastic processes. The data have a significant spectral peak corresponding to the yearly variability cycle and feature quasi-stochastic high-frequency variability components, irrespective of the geographical location or of the local climate. Moreover, the amplitude of this latter feature is shown to be modulated by variations in the yearly cycle, which is indicative of nonlinear multiplicative cross-scale couplings. The study has possible implications on the modeling and the forecast of the surface solar radiation, by clearly discriminating the deterministic from the quasi-stochastic character of the data, at different local timescales.

Further evidence for a broader concept of somatization disorder using the somatic symptom index.

PubMed

Hiller, W; Rief, W; Fichter, M M

1995-01-01

Somatization syndromes were defined in a sample of 102 psychosomatic inpatients according to the restrictive criteria of DSM-III-R somatization disorder and the broader diagnostic concept of the Somatic Symptom Index (SSI). Both groups showed a qualitatively similar pattern of psychopathological comorbidity and had elevated scores on measures of depression, hypochondriasis, and anxiety. A good discrimination between mild and severe forms of somatization was found by using the SSI criterion. SSI use accounted for a substantial amount of comorbidity variance, with rates of 15%-20% for depression, 16% for hypochondriasis, and 13% for anxiety. The results provide further evidence for the validity of the SSI concept, which reflects the clinical relevance of somatization in addition to the narrow definition of somatization disorder.

Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study.

PubMed

2018-05-01

Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world. This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231. Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p<0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05-2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p<0·001). Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication. DFID-MRC-Wellcome Trust Joint Global Health Trial Development Grant, National Institute of Health Research Global Health Research Unit Grant. Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license. Published by Elsevier Ltd.. All rights reserved.

49 CFR 15.15 - SSI disclosed by DOT.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Information Act. (h) Disclosure of Critical Infrastructure Information. Disclosure of information that is both SSI and has been designated as critical infrastructure information under section 214 of the Homeland...

49 CFR 15.15 - SSI disclosed by DOT.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Information Act. (h) Disclosure of Critical Infrastructure Information. Disclosure of information that is both SSI and has been designated as critical infrastructure information under section 214 of the Homeland...

49 CFR 15.15 - SSI disclosed by DOT.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Information Act. (h) Disclosure of Critical Infrastructure Information. Disclosure of information that is both SSI and has been designated as critical infrastructure information under section 214 of the Homeland...

Translation, Assessment and Deployment of Stuttering Instruments into Different Languages: Comments Arising from Bakhtiar et al., "Investigation of the Reliability of the SSI-3 for Preschool Persian-Speaking Children Who Stutter" ["J. Fluency Disord." 35 (2010) 87-91

ERIC Educational Resources Information Center

Karimi, Hamid; Nilipour, Reza; Shafiei, Bijan; Howell, Peter

2011-01-01

Bakhtiar, Seifpanahi, Ansari, Ghanadzade and Packman (2010) reported high inter-, and intra-judge agreement of a translation of the Stuttering Severity Instrument (SSI-3) for preschool Persian-speaking children who stutter. Translation of SSI-3 into Persian is desirable as there is no standardised stuttering severity test for that language.…

20 CFR 416.204 - Redeterminations of SSI eligibility.

Code of Federal Regulations, 2013 CFR

2013-04-01

... AGED, BLIND, AND DISABLED Eligibility General § 416.204 Redeterminations of SSI eligibility. (a... requirements for eligibility other than whether you are still disabled or blind. Continuation of disability or...

20 CFR 416.204 - Redeterminations of SSI eligibility.

Code of Federal Regulations, 2011 CFR

2011-04-01

... AGED, BLIND, AND DISABLED Eligibility General § 416.204 Redeterminations of SSI eligibility. (a... requirements for eligibility other than whether you are still disabled or blind. Continuation of disability or...

20 CFR 416.204 - Redeterminations of SSI eligibility.

Code of Federal Regulations, 2012 CFR

2012-04-01

... AGED, BLIND, AND DISABLED Eligibility General § 416.204 Redeterminations of SSI eligibility. (a... requirements for eligibility other than whether you are still disabled or blind. Continuation of disability or...

20 CFR 416.204 - Redeterminations of SSI eligibility.

Code of Federal Regulations, 2014 CFR

2014-04-01

... AGED, BLIND, AND DISABLED Eligibility General § 416.204 Redeterminations of SSI eligibility. (a... requirements for eligibility other than whether you are still disabled or blind. Continuation of disability or...

Development of remote sensing techniques for assessment of salinity induced plant stresses

NASA Astrophysics Data System (ADS)

Stong, Matthew Harold

Salinity has been shown to reduce vegetative growth, crop quality, and yield in agricultural crops. Remote sensing is capable of providing data about large areas. This project was designed to induce salinity stress in a crop, pak choi, and thereafter monitor the response of the crop as expressed by its spectral reflectances. The project was conducted in the National Taiwan University Phytotron, and spectral data was collected using a GER 2600. Yield and soil salinity (ECe) were also measured. After three seasons of data were collected, wavelengths sensitive to salinity were selected. These wavelengths, which are within the spectral response of biochemicals produced by plants as a response to soil salinity, were used to create two indices, the Salinity Stress Index (SSI) and the Normalized Salinity Stress Index (NSSI). After creating the indices tests were conducted to determine the efficacy of these indices in detecting salinity and drought stresses as compared to existing indices (SRVI and NDVI). This project induced salinity and drought stress in a crop, pak choi, and thereafter monitored the response of the crop as expressed by its spectral reflectances. The SSI and NSSI correlated well to both ECe and marketable yield. Additionally the SSI and NSSI were found to provide statistical differences between salinity stressed treatments and the control treatment. Drought stress was not detected well by any of the indices reviewed although the SSI and NSSI indices tended to increase with drought stress and decrease with salinity stress. As a final test, specific ion toxicities of sodium and chloride were tested against the developed indices (SSI and NSSI) and existing indices (NDVI, SRVI, and NDWI). There were no differences in SSI and NSSI responses to specific ion concentration in the high salinity treatments. These results indicated that the SSI and NSSI are not sensitive to the specific ion concentration in irrigation water. However, the SSI and NSSI were higher for the sodium water than the choride water in the low salinity treatments. It is likely that this difference was caused by the fact that the high SAR water decreased infiltration and caused water stress.

Evaluation on penetration rate of cloud for incoming solar radiation using geostationary satellite data

NASA Astrophysics Data System (ADS)

Yeom, Jong-Min; Han, Kyung-Soo; Kim, Jae-Jin

2012-05-01

Solar surface insolation (SSI) represents how much solar radiance reaches the Earth's surface in a specified area and is an important parameter in various fields such as surface energy research, meteorology, and climate change. This study calculates insolation using Multi-functional Transport Satellite (MTSAT-1R) data with a simplified cloud factor over Northeast Asia. For SSI retrieval from the geostationary satellite data, the physical model of Kawamura is modified to improve insolation estimation by considering various atmospheric constituents, such as Rayleigh scattering, water vapor, ozone, aerosols, and clouds. For more accurate atmospheric parameterization, satellite-based atmospheric constituents are used instead of constant values when estimating insolation. Cloud effects are a key problem in insolation estimation because of their complicated optical characteristics and high temporal and spatial variation. The accuracy of insolation data from satellites depends on how well cloud attenuation as a function of geostationary channels and angle can be inferred. This study uses a simplified cloud factor that depends on the reflectance and solar zenith angle. Empirical criteria to select reference data for fitting to the ground station data are applied to suggest simplified cloud factor methods. Insolation estimated using the cloud factor is compared with results of the unmodified physical model and with observations by ground-based pyranometers located in the Korean peninsula. The modified model results show far better agreement with ground truth data compared to estimates using the conventional method under overcast conditions.

Distribution of Sulfur Dioxide Frost on Io

NASA Technical Reports Server (NTRS)

1997-01-01

Sulfur dioxide, normally a gas at room temperatures, is known to exist on Io's surface as a frost, condensing there from the hot gases emanating from the Io volcanoes. However, the deposition patterns and relation of the frost distribution to the volcanic activity is unknown, since prior measurements lacked the spatial resolution to accurately map the surface frost.

The Galileo Near Infrared Mapping Spectrometer (NIMS) obtained relatively high spatial and spectral resolution images during the C3 orbit, and the characteristic infrared absorptions of sulfur dioxide frost appearing in the spectra were used to produce the SO2 frost map shown on the right. The comparison image on the left (from 1979 Voyager measurements) shows the same view and indicates the surface brightness as seen in visible light.

The frost map shows maximum SO2 concentration as white, lesser amounts as blue coloration, and areas with little or no SO2 as black. The resolution of this map is about 120 km (75 miles), which spans the latitude range 120 W to 270 W.

It is interesting to compare this frost distribution with regions of volcanic activity. Volcanic hotspots identified from NIMS and SSI images occur in many of the dark - low SO2 - areas, a reasonable finding since sulfur dioxide would not condense on such hot regions. The Pele region (to the lower left), N. Colchis hot spots (upper center) and S. Volund (upper right) are good examples of hot spot areas depleted in sulfur dioxide. Much of the rest of this hemisphere of Io has varying amounts of sulfur dioxide present. The most sulfur dioxide-rich area is Colchis Regio, the white area to the right of center.

Of particular interest is the dark area to the south of Colchis Regio. From the study of other NIMS images, it is seen that this region does not have any large, obvious hotspots. However, it is depleted in sulfur dioxide.

The Jet Propulsion Laboratory, Pasadena, CA manages the mission for NASA's Office of Space Science, Washington, DC.

The Jet Propulsion Laboratory, Pasadena, CA manages the mission for NASA's Office of Space Science, Washington, DC.

This image and other images and data received from Galileo are posted on the World Wide Web, on the Galileo mission home page at URL http://galileo.jpl.nasa.gov.

49 CFR 15.9 - Restrictions on the disclosure of SSI.

Code of Federal Regulations, 2012 CFR

2012-10-01

... DOT or DHS component or agency. (d) Additional requirements for critical infrastructure information. In the case of information that is both SSI and has been designated as critical infrastructure...

49 CFR 15.9 - Restrictions on the disclosure of SSI.

Code of Federal Regulations, 2013 CFR

2013-10-01

... DOT or DHS component or agency. (d) Additional requirements for critical infrastructure information. In the case of information that is both SSI and has been designated as critical infrastructure...

49 CFR 15.9 - Restrictions on the disclosure of SSI.

Code of Federal Regulations, 2014 CFR

2014-10-01

... DOT or DHS component or agency. (d) Additional requirements for critical infrastructure information. In the case of information that is both SSI and has been designated as critical infrastructure...

Epidemiology of Surgical Site Infections With Staphylococcus aureus in Europe: Protocol for a Retrospective, Multicenter Study.

PubMed

Mellinghoff, Sibylle C; Vehreschild, Jörg Janne; Liss, Blasius J; Cornely, Oliver A

2018-03-12

Surgical site infections (SSIs) are among the most common hospital acquired infections. While the incidence of SSI in certain indicator procedures is the subject of ongoing surveillance efforts in hospitals and health care systems around the world, SSI rates vary markedly within surgical categories and are poorly represented by routinely monitored indicator procedures (eg, mastectomy or hernia surgery). Therefore, relying on indicator procedures to estimate the burden of SSI is imprecise and introduces bias as hospitals may take special precautions to achieve lower SSI rates. The most common cause of SSI is Staphylococcus aureus (S. aureus), as recently confirmed by a Europe-wide point-prevalence study conducted by the European Centre for Disease Prevention and Control (ECDC). The primary objective of this study is to determine the overall and procedure-specific incidence of S. aureus SSI in Europe. Secondary objectives are the overall and procedure-specific outcomes as well as the economic burden of S. aureus SSI in Europe. Explorative objectives are to characterize the composition of the surgical patient population and to estimate the number of patients at risk for S. aureus SSI. A retrospective, multinational, multicenter cohort study (Staphylococcus aureus Surgical Site Infection Multinational Epidemiology in Europe [SALT] study) with a nested case-control part will be conducted. The study will include all surgical procedures at a participating center in order to prevent selection bias and strengthen the understanding of SSI risk by determining the incidence for all common surgical procedures. Data will be assessed in the cohort population, including 150,000 adult patients who underwent any surgical procedure in 2016, and the case-control population. We will match patients establishing S. aureus SSI 1:1 with controls from the same center. Data on demographics, surgery, and microbiology will be exported from electronic files. More detailed data will be captured from the case-control population. The SALT study will include 13 major or academic surgical centers in Europe, comprising 3 in France, 4 in Germany, 2 in Italy, 3 in Spain, and 1 in the United Kingdom. Sites were selected using a feasibility questionnaire. The SALT study is currently recruiting patients. The aim is to complete recruitment in February 2018 and to close the database in September 2018. The final results are expected by the end of 2018. Results of the SALT study will help to better understand the precise risk of certain procedures. They will also provide insight into the overall and procedure-specific incidence and outcome as well as the economic burden of S. aureus SSI in Europe. Findings of the study may help guide the design of clinical trials for S. aureus vaccines. ClinicalTrials.gov NCT03353532; https://clinicaltrials.gov/ct2/show/NCT03353532 (Archived by WebCite at http://www.webcitation.org/6xAK3gVmO). ©Sibylle C Mellinghoff, Jörg Janne Vehreschild, Blasius J Liss, Oliver A Cornely. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 12.03.2018.

49 CFR 15.17 - Consequences of unauthorized disclosure of SSI.

Code of Federal Regulations, 2013 CFR

2013-10-01

... SECURITY INFORMATION § 15.17 Consequences of unauthorized disclosure of SSI. Violation of this part is... actions for Federal employees. Corrective action may include issuance of an order requiring retrieval of...

49 CFR 1520.17 - Consequences of unauthorized disclosure of SSI.

Code of Federal Regulations, 2014 CFR

2014-10-01

... TRANSPORTATION PROTECTION OF SENSITIVE SECURITY INFORMATION § 1520.17 Consequences of unauthorized disclosure of... issuance of an order requiring retrieval of SSI to remedy unauthorized disclosure or an order to cease...

49 CFR 1520.17 - Consequences of unauthorized disclosure of SSI.

Code of Federal Regulations, 2012 CFR

2012-10-01

... TRANSPORTATION PROTECTION OF SENSITIVE SECURITY INFORMATION § 1520.17 Consequences of unauthorized disclosure of... issuance of an order requiring retrieval of SSI to remedy unauthorized disclosure or an order to cease...

49 CFR 15.17 - Consequences of unauthorized disclosure of SSI.

Code of Federal Regulations, 2014 CFR

2014-10-01

... SECURITY INFORMATION § 15.17 Consequences of unauthorized disclosure of SSI. Violation of this part is... actions for Federal employees. Corrective action may include issuance of an order requiring retrieval of...

49 CFR 15.17 - Consequences of unauthorized disclosure of SSI.

Code of Federal Regulations, 2012 CFR

2012-10-01

... SECURITY INFORMATION § 15.17 Consequences of unauthorized disclosure of SSI. Violation of this part is... actions for Federal employees. Corrective action may include issuance of an order requiring retrieval of...

49 CFR 1520.17 - Consequences of unauthorized disclosure of SSI.

Code of Federal Regulations, 2013 CFR

2013-10-01

... TRANSPORTATION PROTECTION OF SENSITIVE SECURITY INFORMATION § 1520.17 Consequences of unauthorized disclosure of... issuance of an order requiring retrieval of SSI to remedy unauthorized disclosure or an order to cease...

49 CFR 15.17 - Consequences of unauthorized disclosure of SSI.

Code of Federal Regulations, 2011 CFR

2011-10-01

... SECURITY INFORMATION § 15.17 Consequences of unauthorized disclosure of SSI. Violation of this part is... actions for Federal employees. Corrective action may include issuance of an order requiring retrieval of...

49 CFR 15.17 - Consequences of unauthorized disclosure of SSI.

Code of Federal Regulations, 2010 CFR

2010-10-01

... SECURITY INFORMATION § 15.17 Consequences of unauthorized disclosure of SSI. Violation of this part is... actions for Federal employees. Corrective action may include issuance of an order requiring retrieval of...

49 CFR 1520.17 - Consequences of unauthorized disclosure of SSI.

Code of Federal Regulations, 2011 CFR

2011-10-01

... TRANSPORTATION PROTECTION OF SENSITIVE SECURITY INFORMATION § 1520.17 Consequences of unauthorized disclosure of... issuance of an order requiring retrieval of SSI to remedy unauthorized disclosure or an order to cease...

49 CFR 1520.15 - SSI disclosed by TSA or the Coast Guard.

Code of Federal Regulations, 2013 CFR

2013-10-01

... under the Freedom of Information Act. (h) Disclosure of Critical Infrastructure Information. Disclosure of information that is both SSI and has been designated as critical infrastructure information under...

49 CFR 1520.15 - SSI disclosed by TSA or the Coast Guard.

Code of Federal Regulations, 2011 CFR

2011-10-01

... under the Freedom of Information Act. (h) Disclosure of Critical Infrastructure Information. Disclosure of information that is both SSI and has been designated as critical infrastructure information under...

49 CFR 1520.15 - SSI disclosed by TSA or the Coast Guard.

Code of Federal Regulations, 2012 CFR

2012-10-01

... under the Freedom of Information Act. (h) Disclosure of Critical Infrastructure Information. Disclosure of information that is both SSI and has been designated as critical infrastructure information under...

49 CFR 1520.15 - SSI disclosed by TSA or the Coast Guard.

Code of Federal Regulations, 2014 CFR

2014-10-01

... under the Freedom of Information Act. (h) Disclosure of Critical Infrastructure Information. Disclosure of information that is both SSI and has been designated as critical infrastructure information under...

Mono- and polynuclear Co(II) silanethiolates with aliphatic diamines

NASA Astrophysics Data System (ADS)

Pladzyk, Agnieszka; Baranowska, Katarzyna

2014-01-01

Four Co(II) complexes, [Co{SSi(OtBu)3}2(dmpda)] 1, [Co{SSi(OtBu)3}2(bda)2]n2 [Co{SSi(OtBu)3}2(pda)2]n3 and [Co{SSi(OtBu)3}2(hda)2]n4 [dmpda = 3-(dimethylamino)-1-propylamine; bda = 1.4-butanediamine; pda = 1.5-pentanediamine; had = 1.6-hexanediamine] have been synthesized and characterized using X-ray diffraction. Complex 1 is mononuclear and contains Co(II) coordinated by dmpda molecule in chelating mode, whereas compounds 3 and 4 are one-dimensional polymers with pda and hda diamines as bridges between the metallic centers respectively. In all complexes tri-tert-butoxysilanethiolate residue acts as terminal S-donor ligand. Full characterization of obtained compounds 1-4 was additionally carried out with the use of IR and UV-vis spectroscopy, elemental and thermal analysis.

Excess cost and inpatient stay of treating deep spinal surgical site infections.

PubMed

Barnacle, James; Wilson, Dianne; Little, Christopher; Hoffman, Christopher; Raymond, Nigel

2018-05-18

To determine the excess cost and hospitalisation associated with surgical site infections (SSI) following spinal operations in a New Zealand setting. We identified inpatients treated for deep SSI following primary or revision spinal surgery at a regional tertiary spinal centre between 2009 and 2016. Excess cost and excess length of stay (LOS) were calculated via a clinical costing system using procedure-matched controls. Twenty-eight patients were identified. Twenty-five had metalware following spinal fusion surgery, while three had non-instrumented decompression and/or discectomy. Five were diagnosed during their index hospitalisation and 23 (82%) were re-admitted. The average excess SSI cost was NZ$51,434 (range $1,398-$262,206.16) and LOS 37.1 days (range 7-275 days). Infections following metalware procedures had a greater excess cost (average $56,258.90 vs. $11,228.61) and LOS (average 40.4 days vs. 9.7 days) than procedures without metalware. The costs associated with spinal SSI are significant and comparable to a previous New Zealand study of hip and knee prosthesis SSI. More awareness of the high costs involved should encourage research and implementation of infection prevention strategies.

Socioscientific Issues as a Vehicle for Promoting Character and Values for Global Citizens

NASA Astrophysics Data System (ADS)

Lee, Hyunju; Yoo, Jungsook; Choi, Kyunghee; Kim, Sung-Won; Krajcik, Joseph; Herman, Benjamin C.; Zeidler, Dana L.

2013-08-01

Our guiding presupposition in this study was that socioscientific issues (SSI) instruction, given the humanistic features that comprise this type of instruction, could play a role as a vehicle for cultivating character and values as global citizens. Our main objective was to observe how and to what extent SSI instruction might contribute to this. In order to achieve this aim, we implemented a SSI program on genetic modification technology for 132 ninth-grade students over 3-4 weeks and identified its educational effects using a mixed method approach. Data sources included student responses to questionnaire items that measure the students' character and values, records of student discussions, and semi-structured interviews with the students and their teachers. Results indicated that the students became more sensitive to moral and ethical aspects of scientific and technological development and compassionate to diverse people who are either alienated by the benefits of advanced technology or who are vulnerable to the dangers of its unintended effects. In addition, the students felt more responsible for the future resolution of the genetic SSI. However, the students struggled to demonstrate willingness and efficacy to participate within broader communities that entailed action toward SSI resolution.

Morphology and morphometrics of Heterodorus qinghaiensis n. sp. (Dorylaimida, Nordiidae) from soil samples in China.

PubMed

Wu, W J; Yan, L; Xu, C L; Yu, L; Wang, K; Jin, S Y; Xie, H

2016-07-01

One new species of the family Nordiidae Jairajpuri & Siddiqi, 1964 from the enclosure grassland of Qinghai Province, China, Heterodorus qinghaiensis n. sp., is described and illustrated. The new species is characterized by the slender body, 1.29-1.46 mm in length; the granular lateral chord with numerous large depression plaques throughout its entirety; the lip region offset by a distinct depression; amphid goblet-shaped with aperture about half to two-thirds of corresponding body diameter; odontostyle 11-13 μm long; rod-like odontophore without basal flanges; pharyngeal basal expansion about one-third of the total neck length; didelphic genital system containing sperm; ovaries generally not reaching the sphincter level; vulva transversed and sclerotized; female tail conoid with round terminus; 3-5 spaced ventromedial supplements and spicule 32-41 μm long. It is close to H. liangi (Ahmad, Wu & Shaheen, 2002) Andrássy, 2009, H. brevidentatus (Thorne, 1939) Andrássy, 2009, H. monticola Andrássy, 2011, H. morgensis (Loof, 1988) Andrássy, 2009 and H. meghalayensis (Mushtaq, Baniyamuddin & Ahmad, 2007) Andrássy, 2009 in having inconspicuous or no lateral body pores, smaller odontostyle and ventrally curved tail.

20 CFR 416.202 - Who may get SSI benefits.

Code of Federal Regulations, 2014 CFR

2014-04-01

... have more resources than are permitted (subpart L). (e) You are disabled, drug addiction or alcoholism... treatment was available or 36 months of SSI benefits on the basis of disability where drug addiction or...

20 CFR 416.202 - Who may get SSI benefits.

Code of Federal Regulations, 2013 CFR

2013-04-01

... have more resources than are permitted (subpart L). (e) You are disabled, drug addiction or alcoholism... treatment was available or 36 months of SSI benefits on the basis of disability where drug addiction or...

20 CFR 416.202 - Who may get SSI benefits.

Code of Federal Regulations, 2012 CFR

2012-04-01

... have more resources than are permitted (subpart L). (e) You are disabled, drug addiction or alcoholism... treatment was available or 36 months of SSI benefits on the basis of disability where drug addiction or...

20 CFR 416.202 - Who may get SSI benefits.

Code of Federal Regulations, 2011 CFR

2011-04-01

... have more resources than are permitted (subpart L). (e) You are disabled, drug addiction or alcoholism... treatment was available or 36 months of SSI benefits on the basis of disability where drug addiction or...

Storage Reliability of Missile Materiel Program, Monolithic Bipolar SSI/ MSI Digital and Linear Integrated Circuit Analysis

DTIC Science & Technology

1978-01-01

Beam Lead Sealed Junction (ELSJ) devices, the silicon nitride seals the devices from sodium and since the platinum silicide and titanium metals also...improve the surface stability of bipolar devices. These materials act as gettering agents for sodium ions, thus making the contamination far less...electric field, can cause appreciable device parameter instability. Silicon nitride has been shown to be an effective barrier to sodium migration. In

The size distribution of Jupiter's main ring from Galileo imaging and spectroscopy

NASA Astrophysics Data System (ADS)

Brooks, Shawn M.; Esposito, Larry W.; Showalter, Mark R.; Throop, Henry B.

2004-07-01

Galileo's Solid State Imaging experiment (SSI) obtained 36 visible wavelength images of Jupiter's ring system during the nominal mission (Ockert-Bell et al., 1999, Icarus 138, 188-213) and another 21 during the extended mission. The Near Infrared Mapping Spectrometer (NIMS) recorded an observation of Jupiter's main ring during orbit C3 at wavelengths from 0.7 to 5.2 μm; a second observation was attempted during orbit E4. We analyze the high phase angle NIMS and SSI observations to constrain the size distribution of the main ring's micron-sized dust population. This portion of the population is best constrained at high phase angles, as the light scattering behavior of small dust grains dominates at these geometries and contributions from larger ring particles are negligible. High phase angle images of the main ring obtained by the Voyager spacecraft covered phase angles between 173.8° and 176.9° (Showalter et al., 1987, Icarus 69, 458-498). Galileo images extend this range up to 178.6°. We model the Galileo phase curve and the ring spectra from the C3 NIMS ring observation as the combination of two power law distributions. Our analysis of the main ring phase curve and the NIMS spectra suggests the size distribution of the smallest ring particles is a power law with an index of 2.0±0.3 below a size of ˜15 μm that transitions to a power law with an index of 5.0±1.5 at larger sizes. This combined power law distribution, or "broken power law" distribution, yields a better fit to the NIMS data than do the power law distributions that have previously been fit to the Voyager imaging data (Showalter et al., 1987, Icarus 69, 458-498). The broken power law distribution reconciles the results of Showalter et al. (1987, Icarus 69, 458-498) and McMuldroch et al. (2000, Icarus 146, 1-11), who also analyzed the NIMS data, and can be considered as an obvious extension of a simple power law. This more complex size distribution could indicate that ring particle production rates and/or lifetimes vary with size and may relate to the physical processes that control their evolution. The significant near arm/far arm asymmetry reported elsewhere (see Showalter et al., 1987, Icarus 69, 458-498; Ockert-Bell et al., 1999, Icarus 138, 188-213) persists in the data even after the main ring is isolated in the SSI images. However, the sense of the asymmetry seen in Galileo images differs from that seen in Voyager images. We interpret this asymmetry as a broad-scale, azimuthal brightness variation. No consistent association with the magnetic field of Jupiter has been observed. It is possible that these longitudinal variations may be similar to the random brightness fluctuations observed in Saturn's F ring by Voyager (Smith et al., 1982, Science 215, 504-537) and during the 1995 ring plane crossings (Nicholson et al., 1996, Science 272, 509-515; Bosh and Rivkin, 1996, Science 272, 518-521; Poulet et al., 2000, Icarus 144, 135-148). Stochastic events may thus play a significant role in the evolution of the jovian main ring.

Postoperative infection in spine surgery: does the month matter?

PubMed

Durkin, Michael J; Dicks, Kristen V; Baker, Arthur W; Moehring, Rebekah W; Chen, Luke F; Sexton, Daniel J; Lewis, Sarah S; Anderson, Deverick J

2015-07-01

The relationship between time of year and surgical site infection (SSI) following neurosurgical procedures is poorly understood. Authors of previous reports have demonstrated that rates of SSI following neurosurgical procedures performed during the summer months were higher compared with rates during other seasons. It is unclear, however, if this difference was related to climatological changes or inexperienced medical trainees (the July effect). The aim of this study was to evaluate for seasonal variation of SSI following spine surgery in a network of nonteaching community hospitals. The authors analyzed 6 years of prospectively collected surveillance data (January 1, 2007, to December 31, 2012) from all laminectomies and spinal fusions from 20 hospitals in the Duke Infection Control Outreach Network of community hospitals. Surgical site infections were defined using National Healthcare Safety Network criteria and identified using standardized methods across study hospitals. Regression models were then constructed using Poisson distribution to evaluate for seasonal trends by month. Each analysis was first performed for all SSIs and then for SSIs caused by specific organisms or classes of organisms. Categorical analysis was performed using two separate definitions of summer: June through September (definition 1), and July through September (definition 2). The prevalence rate of SSIs during the summer was compared with the prevalence rate during the remainder of the year by calculating prevalence rate ratios and 95% confidence intervals. The authors identified 642 SSIs following 57,559 neurosurgical procedures (overall prevalence rate = 1.11/100 procedures); 215 occurred following 24,466 laminectomies (prevalence rate = 0.88/100 procedures), and 427 following 33,093 spinal fusions (prevalence rate = 1.29/100 procedures). Common causes of SSI were Staphylococcus aureus (n = 380; 59%), coagulase-negative staphylococci (n = 90; 14%), and Escherichia coli (n = 41; 6.4%). Poisson regression models demonstrated increases in the rates of SSI during each of the summer months for all SSIs and SSIs due to gram-positive cocci, S. aureus, and methicillin-sensitive S. aureus. Categorical analysis confirmed that the rate of SSI during the 4-month summer period was higher than the rate during the remainder of the year, regardless of which definition for summer was used (definition 1, p = 0.008; definition 2, p = 0.003). Similarly, the rates of SSI due to grampositive cocci and S. aureus were higher during the summer months than the remainder of the year regardless of which definition of summer was used. However, the rate of SSI due to gram-negative bacilli was not. The rate of SSI following fusion or spinal laminectomy/laminoplasty was higher during the summer in this network of community hospitals. The increase appears to be related to increases in SSIs caused by gram-positive cocci and, more specifically, S. aureus. Given the nonteaching nature of these hospitals, the findings demonstrate that increases in the rate of SSI during the summer are more likely related to ecological and/or environmental factors than the July effect.

Does Administration of Oral Versus Intravenous Antibiotics for Third Molar Removal Have an Effect on the Incidence of Alveolar Osteitis or Postoperative Surgical Site Infections?

PubMed

Reiland, Matthew D; Ettinger, Kyle S; Lohse, Christine M; Viozzi, Christopher F

2017-09-01

To compare the incidence of postoperative alveolar osteitis (AO) and surgical site infections (SSIs) in 2 separate cohorts of patients undergoing elective third molar removal: those who received postoperative oral (PO) antibiotics and those who received perioperative intravenous (IV) antibiotics. A retrospective cohort study of all patients 14 to 30 years old undergoing elective outpatient third molar removal under a single surgeon's service over a 12-year period was completed. Patients undergoing third molar removal during the first 72 months received postoperative PO antibiotics alone. Patients undergoing third molar removal during the second 72 months received perioperative IV antibiotics alone. The primary predictor variable for the study was the antibiotic regimen used at the time of third molar removal. The primary outcome variable was the postoperative development of AO or SSI. Covariates included age and gender. Univariable and multivariable regression models assessed for associations between the antibiotic regimen used and the presence of AO and SSI. The study sample consisted of 1,895 patients (1,020 patients receiving postoperative PO antibiotics and 875 patients receiving perioperative IV antibiotics). Of patients receiving postoperative PO antibiotics, 6.4% developed AO an average of 5.7 days after the procedure and 2.6% developed an SSI an average of 23.2 days after the procedure. Of patients receiving perioperative IV antibiotics, 5.5% developed AO an average of 6.2 days after the procedure and 3.3% developed an SSI an average of 18.2 days after the procedure. No statistically significant associations between the antibiotic regimen used and the presence of AO or SSI were identified in univariable (P = 0.42 for AO, P = 0.32 for SSI) or multivariable (P = 0.65 for AO, P = 0.26 for SSI) analyses. In the postoperative PO antibiotic cohort, older age (P < .001) and female gender (P < .001) were significantly associated with the development of AO, and female gender (P = .015) was significantly associated with the presence of an SSI. In the perioperative IV antibiotic cohort, female gender was significantly associated with the development of AO (P = .011), and younger age was significantly associated with the presence of an SSI (P = .011). The use of a postoperative PO versus a perioperative IV antibiotic regimen does not significantly alter the incidence of AO or SSI after elective third molar removal. If the surgeon chooses to use antibiotics in the setting of third molar surgery, then perioperative IV antibiotics are preferable over postoperative PO antibiotics because they obviate any issues with patient compliance and might be less costly. Copyright © 2017 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

Postoperative Changes in Presepsin Level and Values Predictive of Surgical Site Infection After Spinal Surgery: A Single-Center, Prospective Observational Study.

PubMed

Koakutsu, Tomoaki; Sato, Tetsuya; Aizawa, Toshimi; Itoi, Eiji; Kushimoto, Shigeki

2018-04-15

Single-institutional, prospective observational study. To elucidate the perioperative kinetics of presepsin (PSEP) in patients undergoing spinal surgery, and to evaluate the possibility of PSEP in the early diagnosis of surgical site infection (SSI). Early diagnosis of SSI after spinal surgery is important. Although several biomarkers have been used as early indicators of SSI, the specificity of these markers in SSI diagnosis was not high. PSEP was found as a novel diagnostic marker for bacterial sepsis in 2004. However, its kinetics after spinal surgery and its usefulness in early diagnosis of SSI have never been evaluated. A total of 118 patients who underwent elective spinal surgery were enrolled. PSEP was measured before, immediately after, 1 day after, and 1 week after surgery. In patients without postoperative infection, perioperative kinetics of PSEP were analyzed. PSEP levels in patients with postoperative infection were also recorded separately, and their utility in SSI diagnosis was evaluated. In the 115 patients without postoperative infection, the median PSEP value was 126, 171, 194, and 147 pg/mL before, immediately after, 1 day after, and 1 week after surgery, respectively. Compared with the preoperative value, PSEP was significantly higher immediately after surgery and the next day, and return to the preoperative level 1 week after surgery. The estimated reference value for 95 percentile in patients without postoperative infection was 297 pg/mL 1 week after surgery. In three patients with postoperative infection, higher levels (>300 pg/mL) were observed 1 week after surgery. In patients after spinal surgery without infectious complications, blood levels of PSEP may immediately increase and return to preoperative levels 1 week after surgery. The PSEP value of 300 pg/mL 1 week after surgery might be used as a novel indicator for suspected SSI. 4.

Contributions of human activities to suspended-sediment yield during storm events from a steep, small, tropical watershed, American Samoa

NASA Astrophysics Data System (ADS)

Messina, A. T.; Biggs, T. W.

2014-12-01

Anthropogenic watershed disturbance by agriculture, deforestation, roads, and urbanization can alter the timing, composition, and mass of sediment loads to adjacent coral reefs, causing enhanced sediment stress on corals near the outlets of impacted watersheds like Faga'alu, American Samoa. To quantify the increase in sediment loading to the adjacent priority coral reef experiencing sedimentation stress, suspended-sediment yield (SSY) from undisturbed and human-disturbed portions of a small, steep, tropical watershed was measured during baseflow and storm events of varying magnitude. Data on precipitation, discharge, turbidity, and suspended-sediment concentration (SSC) were collected over three field campaigns and continuous monitoring from January 2012 to March 2014, which included 88 storm events. A combination of paired- and nested-watershed study designs using sediment budget, disturbance ratio, and sediment rating curve methodologies was used to quantify the contribution of human-disturbed areas to total SSY. SSC during base- and stormflows was significantly higher downstream of an open-pit aggregate quarry, indicating the quarry is a key sediment source requiring sediment discharge mitigation. Comparison of event-wise SSY from the upper, undisturbed watershed, and the lower, human-disturbed watershed showed the Lower watershed accounted for more than 80% of total SSY on average, and human activities have increased total sediment loading to the coast by approximately 200%. Four storm characteristics were tested as predictors of event SSY using Pearson's and Spearman's correlation coefficients. Similar to mountainous watersheds in semi-arid and temperate watersheds, SSY from both the undisturbed and disturbed watersheds had the highest correlation with event maximum discharge, Qmax (Pearson's R=0.88 and 0.86 respectively), and were best fit by a power law relationship. The resulting model of event-SSY from Faga'alu is being incorporated as part of a larger project investigating relationships and interactions between terrigenous sediment, water circulation over the reef, and the spatial distribution of sediment accumulation under various conditions in a linked watershed and fringing-reef embayment.

Is Intraoperative Local Vancomycin Powder the Answer to Surgical Site Infections in Spine Surgery?

PubMed

Hey, Hwee Weng Dennis; Thiam, Desmond Wei; Koh, Zhi Seng Darren; Thambiah, Joseph Shantakumar; Kumar, Naresh; Lau, Leok-Lim; Liu, Ka-Po Gabriel; Wong, Hee-Kit

2017-02-15

This is a retrospective cohort comparative study of all patients who underwent instrumented spine surgery at a single institution. To compare the rate of surgical site infection (SSI) between the treatment (vancomycin) and the control group (no vancomycin) in patients undergoing instrumented spine surgery. SSI after spine surgery is a dreaded complication associated with increased morbidity and mortality. Prophylactic intraoperative local vancomycin powder to the wound has been recently adopted as a strategy to reduce SSI but results have been variable. In the present study, there were 117 (30%) patients in the treatment group and 272 (70%) patients in the comparison cohort. All patients received identical standard operative and postoperative care procedures based on protocolized department guidelines. The present study compared the rate of SSI with and without the use of prophylactic intraoperative local vancomycin powder in patients undergoing various instrumented spine surgery, adjusted for confounders. The overall rate of SSI was 4.7% with a decrease in infection rate found in the treatment group (0.9% vs. 6.3%). This was statistically significant (P = 0.049) with an odds ratio of 0.13 (95% confidence interval 0.02-0.99). The treatment group had a significantly shorter onset of infection (5 vs. 16.7 days; P < 0.001) and shorter duration of infection (8.5 vs. 26.8 days; P < 0.001). The most common causative organism was Pseudomonas aeruginosa (35.2%). Patient diagnosis, surgical approach, and intraoperative blood loss were significant risk factors for SSI after multivariable analysis. Prophylactic Intraoperative local vancomycin powder reduces the risk and morbidity of SSI in patients undergoing instrumented spine surgery. P. aeruginosa infection is common in the treatment arm. Future prospective randomized controlled trials in larger populations involving other spine surgeries with a long-term follow-up duration are recommended. 3.

Decoupling Solar Variability and Instrument Trends Using the Multiple Same-Irradiance-Level (MuSIL) Analysis Technique

NASA Astrophysics Data System (ADS)

Woods, Thomas N.; Eparvier, Francis G.; Harder, Jerald; Snow, Martin

2018-05-01

The solar spectral irradiance (SSI) dataset is a key record for studying and understanding the energetics and radiation balance in Earth's environment. Understanding the long-term variations of the SSI over timescales of the 11-year solar activity cycle and longer is critical for many Sun-Earth research topics. Satellite measurements of the SSI have been made since the 1970s, most of them in the ultraviolet, but recently also in the visible and near-infrared. A limiting factor for the accuracy of previous solar variability results is the uncertainties for the instrument degradation corrections, which need fairly large corrections relative to the amount of solar cycle variability at some wavelengths. The primary objective of this investigation has been to separate out solar cycle variability and any residual uncorrected instrumental trends in the SSI measurements from the Solar Radiation and Climate Experiment (SORCE) mission and the Thermosphere, Mesosphere, Ionosphere, Energetic, and Dynamics (TIMED) mission. A new technique called the Multiple Same-Irradiance-Level (MuSIL) analysis has been developed, which examines an SSI time series at different levels of solar activity to provide long-term trends in an SSI record, and the most common result is a downward trend that most likely stems from uncorrected instrument degradation. This technique has been applied to each wavelength in the SSI records from SORCE (2003 - present) and TIMED (2002 - present) to provide new solar cycle variability results between 27 nm and 1600 nm with a resolution of about 1 nm at most wavelengths. This technique, which was validated with the highly accurate total solar irradiance (TSI) record, has an estimated relative uncertainty of about 5% of the measured solar cycle variability. The MuSIL results are further validated with the comparison of the new solar cycle variability results from different solar cycles.

Effect of the application of a bundle of three measures (intraperitoneal lavage with antibiotic solution, fascial closure with Triclosan-coated sutures and Mupirocin ointment application on the skin staples) on the surgical site infection after elective laparoscopic colorectal cancer surgery.

PubMed

Ruiz-Tovar, Jaime; Llavero, Carolina; Morales, Vicente; Gamallo, Carlos

2018-01-18

Surgical site infection (SSI) prevention bundles include the simultaneous use of different measures, which individually have demonstrated an effect on prevention of SSI. The implementation of bundles can yield superior results to the implementation of individual measures. The aim of this study was to address the effect of the application of a bundle including intraperitoneal lavage with antibiotic solution, fascial closure with Triclosan-coated sutures and Mupirocin ointment application on the skin staples, on the surgical site infection after elective laparoscopic colorectal cancer surgery. A prospective, randomized study was performed, including patients with diagnosis of colorectal neoplasms and plans to undergo an elective laparoscopic surgery. The patients were randomized into two groups: those patients following standard bundles (Group 1) and those ones following the experimental bundle with three additional measures, added to the standard bundle. Incisional and organ space SSI were investigated. The study was assessor-blinded. A total of 198 patients were included in the study, 99 in each group. The incisional SSI rate was 16% in Group 1 and 2% in Group 2 [p = 0.007; RR = 5.6; CI 95% (1.4-17.8)]. The organ-space SSI rate was 4% in Group 1 and 0% in Group 2 [p = 0.039; RR = 1.7; CI 95% (1.1-11.6)]. Median hospital stay was 5.5 days in Group 1 and 4 days in Group 2 (p = 0.028). The addition of intraperitoneal lavage with antibiotic solution, fascial closure with Triclosan-coated sutures and Mupirocin ointment application on the skin staples, to a standard bundle of SSI prevention, reduces the incisional and organ-space SSI and consequently the hospital stay, after elective laparoscopic colorectal cancer surgery (ClinicalTrials.gov Identifier: NCT03081962).

Open Surface Solar Irradiance Observations - A Challenge

NASA Astrophysics Data System (ADS)

Menard, Lionel; Nüst, Daniel; Jirka, Simon; Maso, Joan; Ranchin, Thierry; Wald, Lucien

2015-04-01

The newly started project ConnectinGEO funded by the European Commission aims at improving the understanding on which environmental observations are currently available in Europe and subsequently providing an informational basis to close gaps in diverse observation networks. The project complements supporting actions and networking activities with practical challenges to test and improve the procedures and methods for identifying observation data gaps, and to ensure viability in real world scenarios. We present a challenge on future concepts for building a data sharing portal for the solar energy industry as well as the state of the art in the domain. Decision makers and project developers of solar power plants have identified the Surface Solar Irradiance (SSI) and its components as an important factor for their business development. SSI observations are crucial in the process of selecting suitable locations for building new plants. Since in-situ pyranometric stations form a sparse network, the search for locations starts with global satellite data and is followed by the deployment of in-situ sensors in selected areas for at least one year. To form a convincing picture, answers must be sought in the conjunction of these EO systems, and although companies collecting SSI observations are willing to share this information, the means to exchange in-situ measurements across companies and between stakeholders in the market are still missing. We present a solution for interoperable exchange of SSI data comprising in-situ time-series observations as well as sensor descriptions based on practical experiences from other domains. More concretely, we will apply concepts and implementations of the Sensor Web Enablement (SWE) framework of the Open Geospatial Consortium (OGC). The work is based on an existing spatial data infrastructure (SDI), which currently comprises metadata, maps and coverage data, but no in-situ observations yet. This catalogue is already registered in the GEOSS Common Infrastructure (GCI). We describe the challenges and approach to introduce a suite of standards and best practices into the GEO Energy Societal Benefit Area for solar radiation measurements. Challenges range from spatio-temporal coverage across different scales and data quality to intellectual property rights and existing terminology. The approach includes means to share observations based on standardized data and metadata models and a user-friendly data exploration/management tool. The possibility to access and share data considerably improves the information base for strategic planning and control of new solar power resources. The platform will be integrated as a new component into the Webservice-Energy.org GEOSS Community Portal dedicated to Energy and Environment. The ability to provide users with visualisation and download features for in-situ measurements is seen as a key aspect to start engaging the energy community to share, release and integrate more in-situ measurements. This will put to the test the capacity of cooperation in the SSI community by introducing an unprecedented level of collaboration and eventually help to detect gaps in European earth observation networks. The presentation will be an opportunity to seek further collaboration partners and feedback by the community.

Summary of Requirements for Sewage Sludge Incinerators (SSI): New Source Performance Standards (NSPS) and Emission Guidelines (EG)

EPA Pesticide Factsheets

This November 2011 document summarizes the various requirements of the sewage sludge incinerators (SSI) new source performance standards (NSPS) and emission guidelines (EG), broken down into compliance categories.

Surgical Site Infection Reduction Bundle: Implementation and Challenges at Ventura County Medical Center.

PubMed

Losh, Joseph M; Gough, Amy; Rutherford, Richard; Romero, Javier; Diaz, Graal; Schweitzer, Jeremy

2017-10-01

Surgical Site Infections (SSIs) are a significant cause of morbidity and increased cost in the postoperative patient occurring in 2-5 per cent of those undergoing inpatient surgery. Ventura County Medical Center (VCMC) initiated an SSI reduction bundle in 2013, to try to reduce the incidence of SSI. The bundle is a series of best practices including preoperative, perioperative, intraoperative, and postoperative components, as well as items focused on the staff and electronic medical record. VCMC started with a 6.1 per cent SSI rate in 2013. A consistent reduction in SSI rate followed each quarter after that for a rate of less than 2.0 per cent in early 2016. The most critical aspect of this process was the necessary collaboration between disparate departments and the ongoing investment of the staff to this challenging process; the people at the heart of the collaborative process were the key to its success.

Zn(II) and Cd(II) coordination polymers with tri-tert-butoxysilanethiol and bipyridines. Synthesis, crystal structure and spectroscopy

NASA Astrophysics Data System (ADS)

Pladzyk, Agnieszka; Ponikiewski, Łukasz; Stanulewicz, Natalia; Hnatejko, Zbigniew

2013-12-01

Three new zinc(II) and cadmium(II) silanethiolate complexes [Zn{SSi(OtBu)3}2(μ-bpea)ṡCH3CN]n1, [Cd{SSi(OtBu)3}2(μ-bpea)ṡ2CHCl3]n2 and [Cd{SSi(OtBu)3}2(μ-bpey)ṡC7H8]n3 with two bypiridine derivatives, [bpea = 1,2-bis(4-pyridyl)ethane and bpey = 1,2-bis(4-pyridyl)ethylene] have been synthesized and structurally characterized by X-ray crystallography. Their structures and properties have also been established with elemental analysis, IR, TGA and photoluminescent studies. Complexes 1-3 exhibit one-dimensional (1D) chain structures in which [M{SSi(OtBu)3}2] (M = Zn, Cd) units are held together by bpea or bpey bridges, respectively. Complexes are stable up to 300 °C and display blue emissions.

Socioscientific Argumentation: The effects of content knowledge and morality

NASA Astrophysics Data System (ADS)

Sadler, Troy D.; Donnelly, Lisa A.

2006-10-01

Broad support exists within the science education community for the incorporation of socioscientific issues (SSI) and argumentation in the science curriculum. This study investigates how content knowledge and morality contribute to the quality of SSI argumentation among high school students. We employed a mixed-methods approach: 56 participants completed tests of content knowledge and moral reasoning as well as interviews, related to SSI topics, which were scored based on a rubric for argumentation quality. Multiple regression analyses revealed no statistically significant relationships among content knowledge, moral reasoning, and argumentation quality. Qualitative analyses of the interview transcripts supported the quantitative results in that participants very infrequently revealed patterns of content knowledge application. However, most of the participants did perceive the SSI as moral problems. We propose a “Threshold Model of Knowledge Transfer” to account for the relationship between content knowledge and argumentation quality. Implications for science education are discussed.

Adaptive Correlation Concepts for Non-Compatible Imagery.

DTIC Science & Technology

1981-10-31

5.4 Ohio Files 26 and 27 Image Segments . . . . 34 5.5 HSV Files 9 and 10 Image Segments ..... . 35 5.6 Scene 1 , Vertical Profiles Through Peak...Simulation Options Summary .e m "lch c .i a ir t.e j-r.-ct cross c t.e"P- lat absclut - differcr.ce a!a .u iy-i.cidd dif’err.c; - metrics. e 1 T0 1ff ct of...cdlf o spectral bands, di~ffe,-,-rurt tie f loy. "Ind d:;7o T hes’,-e -simu lat i onso ae 1 - s o2( 1 r 1 b- in th I s-,sI 31. / / s. ILI Z1.I I SO .& i

False Color Aurora

NASA Technical Reports Server (NTRS)

1997-01-01

Data from NASA's Galileo spacecraft were used to produce this false-color composite of Jupiter's northern aurora on the night side of the planet. The height of the aurora, the thickness of the auroral arc, and the small-scale structure are revealed for the first time. Images in Galileo's red, green, and clear filters are displayed in red, green, and blue respectively. The smallest resolved features are tens of kilometers in size, which is a ten-fold improvement over Hubble Space Telescope images and a hundred-fold improvement over ground-based images.

The glow is caused by electrically charged particles impinging on the atmosphere from above. The particles travel along Jupiter's magnetic field lines, which are nearly vertical at this latitude. The auroral arc marks the boundary between the 'closed' field lines that are attached to the planet at both ends and the 'open' field lines that extend out into interplanetary space. At the boundary the particles have been accelerated over the greatest distances, and the glow is especially intense.

The latitude-longitude lines refer to altitudes where the pressure is 1 bar. The image shows that the auroral emissions originate about 500 kilometers (about 310 miles) above this surface. The colored background is light scattered from Jupiter's bright crescent, which is out of view to the right. North is at the top. The images are centered at 57 degrees north and 184 degrees west and were taken on April 2, 1997 at a range of 1.7 million kilometers (1.05 million miles) by Galileo's Solid State Imaging (SSI) system.

The Jet Propulsion Laboratory, Pasadena, CA manages the mission for NASA's Office of Space Science, Washington, DC.

This image and other images and data received from Galileo are posted on the World Wide Web, on the Galileo mission home page at: http:// galileo.jpl.nasa.gov. Background information and educational context for the images can be found at: http:/ /www.jpl.nasa.gov/galileo/sepo.

SORCE 11 years after launch: What's new? What's next?

NASA Astrophysics Data System (ADS)

Cahalan, Robert; Kopp, Greg; Pilewskie, Peter; Richard, Erik; Woods, Tom

2014-05-01

We discuss recent changes in estimates of the Total Solar Irradiance (TSI) and the energy budget. We highlight the historic closing of the calibration gap between the suite of TSI instruments, due largely to comparisons made with a cryogenic Transfer Radiometer Facility (TRF) located at the University of Colorado, built by UCO/LASP with support from NASA and NIST. The resulting continuous record of TSI promises to be a milestone in improving understanding of the Sun's impact on Earth's climate. Climate models are sensitive not only to TSI, but also to variations in the Spectral Solar Irradiance (SSI), and the vertical profiles of temperature and ozone are especially sensitive to SSI variations. Variations in SSI need further study before they may be considered as firmly established as TSI variations, which themselves remain controversial, despite a strengthening consensus over the SORCE epoch. The TSIS SIM has recently undergone comprehensive end-to-end calibration in the LASP SSI Radiometry Facility (SRF) utilizing the NIST SIRCUS laser system covering 210 - 2400 nm for SSI, a facility not yet available when SORCE launched in 2003. With SORCE follow-on missions such as the Total and Spectral Solar Irradiance Sensor (TSIS), we anticipate narrowing uncertainties in SSI variability that will be important to improving our understanding of the climate responses to solar forcing. The long-term goal of improving the ability to monitor Earth's energy balance, and the energy imbalance that drives global warming, will need continued improvements in the measurement of both shortwave solar and longwave earth-emitted radiation.

Perioperative antibiotics for surgical site infection in pancreaticoduodenectomy: does the SCIP-approved regimen provide adequate coverage?

PubMed

Donald, Graham W; Sunjaya, Dharma; Lu, Xuyang; Chen, Formosa; Clerkin, Barbara; Eibl, Guido; Li, Gang; Tomlinson, James S; Donahue, Timothy R; Reber, Howard A; Hines, Oscar J

2013-08-01

The Joint Commission Surgical Care Improvement Project (SCIP) includes performance measures aimed at reducing surgical site infections (SSI). One measure defines approved perioperative antibiotics for general operative procedures. However, there may be a subset of procedures not adequately covered with the use of approved antibiotics. We hypothesized that piperacillin-tazobactam is a more appropriate perioperative antibiotic for pancreaticoduodenectomy (PD). In collaboration with hospital epidemiology and the Division of Infectious Diseases, we retrospectively reviewed records of 34 patients undergoing PD between March and May 2008 who received SCIP-approved perioperative antibiotics and calculated the SSI rate. After changing our perioperative antibiotic to piperacillin-tazobactam, we prospectively reviewed PDs performed between June 2008 and March 2009 and compared the SSI rates before and after the change. For 34 patients from March through May 2008, the SSI rate for PD was 32.4 per 100 cases. Common organisms from wound cultures were Enterobacter and Enterococcus (50.0% and 41.7%, respectively), and these were cefoxitin resistant. From June 2008 through March 2009, 106 PDs were performed. During this period, the SSI rate was 6.6 per 100 surgeries, 80% lower than during March through May 2008 (relative risk, 0.204; 95% confidence interval [CI], 0.086-0.485; P = .0004). Use of piperacillin-tazobactam as a perioperative antibiotic in PD may reduce SSI compared with the use of SCIP-approved antibiotics. Continued evaluation of SCIP performance measures in relationship to patient outcomes is integral to sustained quality improvement. Copyright © 2013 Mosby, Inc. All rights reserved.

Children with Special Health Care Needs, Supplemental Security Income, and Food Insecurity.

PubMed

Rose-Jacobs, Ruth; Fiore, Jennifer Goodhart; de Cuba, Stephanie Ettinger; Black, Maureen; Cutts, Diana B; Coleman, Sharon M; Heeren, Timothy; Chilton, Mariana; Casey, Patrick; Cook, John; Frank, Deborah A

2016-01-01

To assess food insecurity in low-income households with young children with/without special health care needs (SHCN) and evaluate relationships between child Supplemental Security Income (SSI) receipt and food insecurity. A cross-sectional survey (2013-2015) of caregivers was conducted at 5 medical centers. Eligibility included index child age <48 months without private health insurance and a caregiver fluent in English or Spanish. Interviews included sociodemographics, 5-item Children with Special Health Care Needs Screener, 18-item US Food Security Survey Module, household public assistance program participation, and child SSI receipt. Household and child food insecurity, each, were evaluated using multivariable logistic regression models. Of 6724 index children, 81.5% screened negative for SHCN, 14.8% positive for SHCN (no SSI), and 3.7% had SHCN and received SSI. After covariate control, households, with versus without a child with SHCN, were more likely to experience household (Adjusted odds ratios [AOR] 1.24, 95% confidence intervals [CI], 1.03-1.48) and child (AOR 1.35, 95% CI, 1.11-1.63) food insecurity. Among households with children with SHCN, those with children receiving, versus not receiving SSI, were more likely to report household (AOR 1.42, 95% CI, 0.97-2.09) but not child food insecurity. Low-income households with young children having SHCN are at risk for food insecurity, regardless of child SSI receipt and household participation in other public assistance programs. Policy recommendations include reevaluation of assistance programs' income and medical deduction criteria for households with children with SHCN to decrease the food insecurity risk faced by these children and their families.

Intraoperative red blood cell transfusion, delayed graft function, and infection after kidney transplant: an observational cohort study.

PubMed

Mazzeffi, Michael; Jonna, Srikar; Blanco, Natalia; Mavrothalassitis, Orestes; Odekwu, Obi; Fontaine, Magali; Rock, Peter; Tanaka, Kenichi; Thom, Kerri

2018-06-01

Kidney transplant patients are frequently anemic and at risk for red blood cell (RBC) transfusion. Previous studies suggest that pre-transplant RBC transfusion may improve kidney transplant outcomes; however, RBC transfusion is also associated with infection. The purpose of our study was to characterize the relationships between intraoperative RBC transfusion, delayed graft function (DGF), postoperative surgical site infection (SSI), and sepsis. Analysis was performed on a historical cohort of adult kidney transplant patients from a single medical center during a two-year period. Crude odds ratios for DGF, superficial and deep SSI, and sepsis were calculated for transfused patients and multivariate regression was used to control for potential confounders when significant relationships were identified. Four hundred forty-one patients had kidney transplant during the study period; 27.0% had RBC transfusion, 38.8% had DGF, 7.0% had superficial SSI, 7.9% had deep SSI, and 1.8% had sepsis. High dose RBC transfusion was associated with improved graft function, but this was negated after adjusting for confounders (OR = 0.86, 95% CI  0.26 to 2.88). There was no association between RBC transfusion and SSI. RBC transfusion was independently associated with sepsis (OR = 8.98, 95% CI  1.52 to 53.22), but the confidence interval was wide. Intraoperative RBC transfusion during kidney transplant is not associated with improved allograft function or incisional SSI, but is associated with postoperative sepsis. RBCs should not be liberally transfused during kidney transplant surgery to improve graft outcomes.

Cost-benefit analysis of craniocerebral surgical site infection control in tertiary hospitals in China.

PubMed

Zhou, Jiong; Ma, Xiaojun

2015-02-19

Surgical site infection (SSI) is one of the most common postoperative complications. This study aimed to determine the cost of SSIs and to evaluate whether SSI control can reduce medical costs under the current medical payment system and wage rates in China. Prospective surveillance of craniocerebral surgery was conducted between July 2009 and June 2012. SSI patients and non-SSI patients were matched with a ratio of 1:2. Terms such as medical costs and length of hospital stay were compared between the two groups. Based on the economic loss of hospital infection, which causes additional expenditures and a reduction in the number of patients treated, the benefits of hospital infection control were estimated. The costs of human resources and materials of hospital infection surveillance and control were also estimated. Finally, the cost-benefit rates in different medical contexts and with different SSI-case ratios were calculated. The incidence of SSIs in this study was 4%. SSIs significantly prolonged hospital stay by 11.75 days (95% CI: 6.24-22.52), increased medical costs by US $3,412.48 (95% CI: $1,680.65-$5,879.89). The direct economic loss was $114,903 in a 40-bed ward. The cost of implementing infection control in such a unit was calculated to be approximately $5,555.47 CONCLUSIONS: Under the current fee-for-service healthcare model in China, the control of SSIs can hardly yield direct economic benefits, but can yield social benefits. With the implementation of a total medical cost pre-payment system, SSI control will present a remarkable benefit-cost ratio for hospitals.

Tailoring the operative approach for appendicitis to the patient: a prediction model from national surgical quality improvement program data.

PubMed

Senekjian, Lara; Nirula, Raminder

2013-01-01

Laparoscopic appendectomy (LA) is increasingly being performed in the United States, despite controversy about differences in infectious complication rates compared with open appendectomy (OA). Subpopulations exist in which infectious complication rates, both surgical site and organ space, differ with respect to LA compared with OA. All appendectomies in the National Surgical Quality Improvement Program database were analyzed with respect to surgical site infection (SSI) and organ space infection (OSI). Multivariate logistic regression analysis identified independent predictors of SSI or OSI. Probabilities of SSI or OSI were determined for subpopulations to identify when LA was superior to OA. From 2005 to 2009, there were 61,830 appendectomies performed (77.5% LA), of which 9,998 (16.2%) were complicated (58.7% LA). The risk of SSI was considerably lower for LA in both noncomplicated and complicated appendicitis. Across all ages, body mass index, renal function, and WBCs, LA was associated with a lower probability of SSI. The risk of OSI was considerably greater for LA in both noncomplicated and complicated appendicitis. In complicated appendicitis, OA was associated with a lower probability of OSI in patients with WBC >12 cells × 10(3)/μL. In noncomplicated appendicitis, OA was associated with a lower probability of OSI in patients with a body mass index <37.5 when compared with LA. Subpopulations exist in which OA is superior to LA in terms of OSI, however, SSI is consistently lower in LA patients. Copyright © 2013 American College of Surgeons. Published by Elsevier Inc. All rights reserved.

Human impact on sediment fluxes within the Blue Nile and Atbara River basins

NASA Astrophysics Data System (ADS)

Balthazar, Vincent; Vanacker, Veerle; Girma, Atkilt; Poesen, Jean; Golla, Semunesh

2013-01-01

A regional assessment of the spatial variability in sediment yields allows filling the gap between detailed, process-based understanding of erosion at field scale and empirical sediment flux models at global scale. In this paper, we focus on the intrabasin variability in sediment yield within the Blue Nile and Atbara basins as biophysical and anthropogenic factors are presumably acting together to accelerate soil erosion. The Blue Nile and Atbara River systems are characterized by an important spatial variability in sediment fluxes, with area-specific sediment yield (SSY) values ranging between 4 and 4935 t/km2/y. Statistical analyses show that 41% of the observed variation in SSY can be explained by remote sensing proxy data of surface vegetation cover, rainfall intensity, mean annual temperature, and human impact. The comparison of a locally adapted regression model with global predictive sediment flux models indicates that global flux models such as the ART and BQART models are less suited to capture the spatial variability in area-specific sediment yields (SSY), but they are very efficient to predict absolute sediment yields (SY). We developed a modified version of the BQART model that estimates the human influence on sediment yield based on a high resolution composite measure of local human impact (human footprint index) instead of countrywide estimates of GNP/capita. Our modified version of the BQART is able to explain 80% of the observed variation in SY for the Blue Nile and Atbara basins and thereby performs only slightly less than locally adapted regression models.

The role of Amicar in same-day anterior and posterior spinal fusion for idiopathic scoliosis.

PubMed

Thompson, George H; Florentino-Pineda, Ivan; Poe-Kochert, Connie; Armstrong, Douglas G; Son-Hing, Jochen P

2008-09-15

A retrospective study of the effectiveness of Amicar (epsilon aminocaproic acid). Evaluate the effectiveness of Amicar in decreasing perioperative blood loss and transfusion requirements in same-day anterior (ASF) and posterior spinal fusion (PSF) with segmental spinal instrumentation (SSI) for idiopathic scoliosis. Preliminary prospective, prospective randomized double-blind, and fibrinogen studies have demonstrated Amicar to be effective in decreasing perioperative blood loss in patients with idiopathic scoliosis undergoing PSF with SSI. Increased fibrinogen secretion is a possible explanation. There were 73 consecutive patients divided into 3 study groups based on the administration of Amicar: Group 1 (n = 16), no Amicar; Group 2 (n = 18), Amicar for the PSF with SSI only; and Group 3 (n = 39), Amicar for both ASF and PSF with SSI. All patients were managed using the same general anesthesia technique, intraoperative procedure, postoperative care path, and indications for transfusion (hemoglobin <7 g/dL). Total perioperative blood loss (estimated intraoperative blood loss for both procedures and measured postoperative chest tube and PSF wound suction drainage) and total transfusion requirements between groups were compared using one-way ANOVA. There were statistically significant decreases in mean estimated intraoperative PSF with SSI, total perioperative blood loss, and transfusion requirements in the 2 Amicar groups. However, Amicar had no significant effect on estimated intraoperative ASF blood loss, chest tube drainage, or PSF wound suction drainage. Total perioperative blood loss and transfusion requirements (cell saver, autologous, directed, and allogeneic blood) were: 3442.8 +/- 1344.0 mL and 1537.1 +/- 905.1 mL in Group 1; 2089.8 +/- 684.0 mL and 485.2 +/- 349.8 mL in Group 2; and 2184.1 +/- 1163.7 mL and 531.5 +/- 510.5 mL in Group 3. There were no Amicar related complications. Amicar was highly effective in decreasing total perioperative blood loss and transfusion requirements in same-day ASF and PSF with SSI for idiopathic scoliosis. It results in less preoperative autologous blood donation, perioperative blood transfusion, costs, and potential transfusion-related complications. It was most effective in decreasing intraoperative estimated PSF with SSI blood loss. It had no significant effect during the ASF, postoperative chest tube, or PSF wound suction drainage. We now recommend that it be used for the PSF with SSI procedure only.

Predictors of surgical site infection in laparoscopic and open ventral incisional herniorrhaphy.

PubMed

Kaafarani, Haytham M A; Kaufman, Derrick; Reda, Domenic; Itani, Kamal M F

2010-10-01

Surgical site infection (SSI) after ventral incisional hernia repair (VIH) can result in serious consequences. We sought to identify patient, procedure, and/or hernia characteristics that are associated with SSI in VIH. Between 2004 and 2006, patients were randomized in four Veteran Affairs (VA) hospitals to undergo laparoscopic or open VIH. Patients who developed SSI within eight weeks postoperatively were compared to those who did not. A bivariate analysis for each factor and a multiple logistic regression analysis were performed to determine factors associated with SSI. The variables studied included patient characteristics and co-morbidities (e.g., age, gender, race, ethnicity, body mass index, ASA classification, diabetes, steroid use), hernia characteristics (e.g., size, duration, number of previous incisions), procedure characteristics (e.g., open versus laparoscopic, blood loss, use of postoperative drains, operating room temperature) and surgeons' experience (resident training level, number of open VIH previously performed by the attending surgeon). Antibiotic prophylaxis, anticoagulation protocols, preparation of the skin, draping of the wound, body temperature control, and closure of the surgical site were all standardized and monitored throughout the study period. Out of 145 patients who underwent VIH, 21 developed a SSI (14.5%). Patients who underwent open VIH had significantly more SSIs than those who underwent laparoscopic VIH (22.1% versus 3.4%; P = 0.002). Among patients who underwent open VIH, those who developed SSI had a recorded intraoperative blood loss greater than 25 mL (68.4% versus 40.3%; P = 0.030), were more likely to have a drain placed (79.0% versus 49.3%; P = 0.021) and were more likey to be operated on by surgeons with less than 75 open VIH case experience (52.6% versus 28.4%; P = 0.048). Patient and hernia characteristics were similar between the two groups. In a multiple logistic regression analysis, the open surgical technique was associated with SSI (OR 8.03, 95% CI 2.03, 31.72; P = 0.003) while controlling for the VA medical center where the procedure was performed (P = 0.041). Open surgical technique and the medical center rather than patient co-morbidities or hernia characteristics are associated with the formation of postoperative SSI in VIH. Published by Elsevier Inc.

Risk factors for superficial surgical site infection after elective rectal cancer resection: a multivariate analysis of 8880 patients from the American College of Surgeons National Surgical Quality Improvement Program database.

PubMed

Sutton, Elie; Miyagaki, Hiromichi; Bellini, Geoffrey; Shantha Kumara, H M C; Yan, Xiaohong; Howe, Brett; Feigel, Amanda; Whelan, Richard L

2017-01-01

Superficial surgical site infection (sSSI) is one of the most common complications after colorectal resection. The goal of this study was to determine the comorbidities and operative characteristics that place patients at risk for sSSI in patients who underwent rectal cancer resection. The American College of Surgeons National Surgical Quality Improvement Program database was queried (via diagnosis and Current Procedural Terminology codes) for patients with rectal cancer who underwent elective resection between 2005 and 2012. Patients for whom data concerning 27 demographic factors, comorbidities, and operative characteristics were available were eligible. A univariate and multivariate analysis was performed to identify possible risk factors for sSSI. A total of 8880 patients met the entry criteria and were included. sSSIs were diagnosed in 861 (9.7%) patients. Univariate analysis found 14 patients statistically significant risk factors for sSSI. Multivariate analysis revealed the following risk factors: male gender, body mass index (BMI) >30, current smoking, history of chronic obstructive pulmonary disease (COPD), American Society of Anesthesiologists III/IV, abdominoperineal resection (APR), stoma formation, open surgery (versus laparoscopic), and operative time >217 min. The greatest difference in sSSI rates was noted in patients with COPD (18.9 versus 9.5%). Of note, 54.2% of sSSIs was noted after hospital discharge. With regard to the timing of presentation, univariate analysis revealed a statistically significant delay in sSSI presentation in patients with the following factors and/or characteristics: BMI <30, previous radiation therapy (RT), APR, minimally invasive surgery, and stoma formation. Multivariate analysis suggested that only laparoscopic surgery (versus open) and preoperative RT were risk factors for delay. Rectal cancer resections are associated with a high incidence of sSSIs, over half of which are noted after discharge. Nine patient and operative characteristics, including smoking, BMI, COPD, APR, and open surgery were found to be significant risk factors for SSI on multivariate analysis. Furthermore, sSSI presentation in patients who had laparoscopic surgery and those who had preoperative RT is significantly delayed for unclear reasons. Copyright © 2016 Elsevier Inc. All rights reserved.

Reliability and validity of the student stress inventory-stress manifestations questionnaire and its association with personal and academic factors in university students.

PubMed

Simonelli-Muñoz, Agustín J; Balanza, Serafín; Rivera-Caravaca, José Miguel; Vera-Catalán, Tomás; Lorente, Ana María; Gallego-Gómez, Juana I

2018-05-01

Stress affects us in every environment and it is also present in the educational sphere. Previous studies have reported a high prevalence of stress in university students. The Student Stress Inventory-Stress Manifestations (SSI-SM), identify stressors and evaluate stress manifestations in adolescents but its validity in university students remains uncertain. We aimed to determine the internal consistency and validity of an adapted version of the Student Stress Inventory-Stress Manifestations (SSI-SM) for university students and to investigate if high stress levels are associated with personal and academic factors. In this quantitative, descriptive, cross-sectional study, we included 115 university students of the Nursing Degree during the second semester of the 2014/2015 academic year. Information about personal issues, lifestyle and academic performance was recorded and the stress was evaluated with the SSI-SM questionnaire. The internal consistency and homogeneity of the SSI-SM questionnaire was tested and a factorial analysis was performed. After the homogeneity analysis, the final version of the SSI-SM questionnaire included 19 items, with a Cronbach's alpha of 0.924. In the factorial analysis, 4 factors were found ('Self-concept', 'Sociability', 'Uncertainty' and 'Somatization'; all Cronbach's alpha >0.700). Students with higher values on the SSI-SM were, in overall, women (41.0 ± 12.7 vs. 33.2 ± 9.5; p = 0.001) and had significantly more family conflicts (47.6 ± 13.8 vs. 35.2 ± 9.6; p < 0.001), consumed less alcohol (R = -0.184, p = 0.048), slept less hours (R = -0.193, p = 0.038) and had worse academic performance in Clinical Nursing (36.3 ± 10.4 vs. 41.2 ± 13.3, p = 0.039). After exclude three items of the original SSI-SM, higher scores in the SSI-SM are correlated with stress level in a cohort of university students of the Nursing Degree. Family conflicts, female gender, absence of alcohol consumption, few sleep hours and poor academic performance are associated with higher stress levels. Copyright © 2018 Elsevier Ltd. All rights reserved.

Dynamic Downscaling of Seasonal Simulations over South America.

NASA Astrophysics Data System (ADS)

Misra, Vasubandhu; Dirmeyer, Paul A.; Kirtman, Ben P.

2003-01-01

In this paper multiple atmospheric global circulation model (AGCM) integrations at T42 spectral truncation and prescribed sea surface temperature were used to drive regional spectral model (RSM) simulations at 80-km resolution for the austral summer season (January-February-March). Relative to the AGCM, the RSM improves the ensemble mean simulation of precipitation and the lower- and upper-level tropospheric circulation over both tropical and subtropical South America and the neighboring ocean basins. It is also seen that the RSM exacerbates the dry bias over the northern tip of South America and the Nordeste region, and perpetuates the erroneous split intertropical convergence zone (ITCZ) over both the Pacific and Atlantic Ocean basins from the AGCM. The RSM at 80-km horizontal resolution is able to reasonably resolve the Altiplano plateau. This led to an improvement in the mean precipitation over the plateau. The improved resolution orography in the RSM did not substantially change the predictability of the precipitation, surface fluxes, or upper- and lower-level winds in the vicinity of the Andes Mountains from the AGCM. In spite of identical convective and land surface parameterization schemes, the diagnostic quantities, such as precipitation and surface fluxes, show significant differences in the intramodel variability over oceans and certain parts of the Amazon River basin (ARB). However, the prognostic variables of the models exhibit relatively similar model noise structures and magnitude. This suggests that the model physics are in large part responsible for the divergence of the solutions in the two models. However, the surface temperature and fluxes from the land surface scheme of the model [Simplified Simple Biosphere scheme (SSiB)] display comparable intramodel variability, except over certain parts of ARB in the two models. This suggests a certain resilience of predictability in SSiB (over the chosen domain of study) to variations in horizontal resolution. It is seen in this study that the summer precipitation over tropical and subtropical South America is highly unpredictable in both models.

The thermal evolution and dynamo generation of Mercury with an Fe-Si core

NASA Astrophysics Data System (ADS)

Knibbe, Jurrien

2017-04-01

The present day partially liquid (as opposed to fully solidified) Fe-rich core of Mercury is traditionally explained by assuming a substantial amount of S to be present in the core (e.g. Grott et al., 2011), because S lowers the core's melting temperature. However, this assumption has problematic implications: Mercury's large Fe-rich core and measured low FeO surface content are indicative of an oxygen poor bulk composition, which is consistent with the volatile-poor material that is expected to have condensed from the solar nebula close to the Sun. In contrast, S is a moderately volatile element. Combined with the high S content of Mercury's crust and (likely) mantle, as indicated by the measured high S/Si surface fraction, the resulting high planetary S abundance is difficult to reconcile with a volatile poor origin of the planet. Additionally, the observed low magnetic field strength is most easily explained if compositional buoyancy fluxes are absent [Manglik et al., 2010], yet such fluxes are produced upon solidifying a pure Fe inner core from Fe-S liquid. Alternatively, both Mercury's high S/Si and Mg/Si surface ratios (Nittler et al., 2011) may indicate that a siderophile fractionation of Si and lithophile fractionation of S took place during Mercury's core-mantle differentiation. This fractionation behaviour of these elements is supported by metal/silicate partitioning experiments that have been performed at the low oxygen conditions inferred for Mercury [e.g. Chabot et al., 2014]. Mercury's bulk composition, in terms of S/Si and Fe/Si ratios, would also approach that of meteorites that are considered as potential building blocks of the planet if the core is Si-rich and S-poor. Here we simulate the thermal evolution of Mercury with an Fe-Si core. Results show that an Fe-Si core can remain largely molten until present, without the need for S. An Fe-Si core also has interesting implications for Mercury's core-convection regime and magnetic field generation. The non-preferential Si fractionation between solid and liquid metal does not produce a compositional gradient, such that compositional buoyancy fluxes are negligible. Additionally, thermally driven core convection is more efficient as a result of a high latent heat release upon solidifying Si-rich metal. Implications of this scenario for Mercury's magnetic field strength and geometry need to be further examined.

20 CFR 416.1321 - Suspension for not giving us permission to contact financial institutions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... we think it is necessary to determine your SSI eligibility or payment amount, or if you cancel the... financial records about that person when we think it is necessary to determine your SSI eligibility or...

49 CFR 1520.13 - Marking SSI.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Transportation Other Regulations Relating to Transportation (Continued) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY SECURITY RULES FOR ALL MODES OF TRANSPORTATION PROTECTION OF SENSITIVE SECURITY INFORMATION § 1520.13 Marking SSI. (a) Marking of paper records. In the case of paper records...

49 CFR 1520.19 - Destruction of SSI.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Transportation Other Regulations Relating to Transportation (Continued) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY SECURITY RULES FOR ALL MODES OF TRANSPORTATION PROTECTION OF SENSITIVE SECURITY INFORMATION § 1520.19 Destruction of SSI. (a) DHS. Subject to the requirements of the Federal...

Prophylactic Bracing Has No Effect on Lower Extremity Alignment or Functional Performance.

PubMed

Hueber, Garrett A; Hall, Emily A; Sage, Brad W; Docherty, Carrie L

2017-07-01

Prophylactic ankle bracing is commonly used during physical activity. Understanding how bracing affects body mechanics is critically important when discussing both injury prevention and sport performance. The purpose is to determine if ankle bracing affects lower extremity mechanics during the Landing Error Scoring System test (LESS) and Sage Sway Index (SSI). Thirty physically active participants volunteered for this study. Participants completed the LESS and SSI in both a braced and unsupported conditions. Total errors were recorded for the LESS. Total errors and time (seconds) were recorded for the SSI. The Wilcoxon signed-rank test was utilized to evaluate any differences between the brace conditions for each dependent variable. A priori alpha level was set at p<0.05. The Wilcoxon signed-rank test yielded no significant difference between the braced and unsupported conditions for the LESS (Z=-0.35, p=0.72), SSI time (Z=-0.36, p=0.72), or SSI Errors (Z=-0.37, p=0.71). Ankle braces had no effect on subjective clinical assessments of lower extremity alignment or postural stability. Utilization of a prophylactic support at the ankle did not substantially alter the proximal components of the lower kinetic chain. © Georg Thieme Verlag KG Stuttgart · New York.

Students' Participation in an Interdisciplinary, Socioscientific Issues Based Undergraduate Human Biology Major and Their Understanding of Scientific Inquiry

NASA Astrophysics Data System (ADS)

Eastwood, Jennifer L.; Sadler, Troy D.; Sherwood, Robert D.; Schlegel, Whitney M.

2013-06-01

The purpose of this study was to examine whether Socioscientific Issues (SSI) based learning environments affect university students' epistemological understanding of scientific inquiry differently from traditional science educational contexts. We identify and compare conceptions of scientific inquiry of students participating in an interdisciplinary, SSI-focused undergraduate human biology major (SSI) and those participating in a traditional biology major (BIO). Forty-five SSI students and 50 BIO students completed an open-ended questionnaire examining their understanding of scientific inquiry. Eight general themes including approximately 60 subthemes emerged from questionnaire responses, and the numbers of students including each subtheme in their responses were statistically compared between groups. A subset of students participated in interviews, which were used to validate and triangulate questionnaire data and probe students' understanding of scientific inquiry in relation to their majors. We found that both groups provided very similar responses, differing significantly in only five subthemes. Results indicated that both groups held generally adequate understandings of inquiry, but also a number of misconceptions. Small differences between groups supported by both questionnaires and interviews suggest that the SSI context contributed to nuanced understandings, such as a more interdisciplinary and problem-centered conception of scientific inquiry. Implications for teaching and research are discussed.

Supplemental security income and social security disability insurance coverage among long-term childhood cancer survivors.

PubMed

Kirchhoff, Anne C; Parsons, Helen M; Kuhlthau, Karen A; Leisenring, Wendy; Donelan, Karen; Warner, Echo L; Armstrong, Gregory T; Robison, Leslie L; Oeffinger, Kevin C; Park, Elyse R

2015-06-01

Supplemental security income (SSI) and social security disability insurance (DI) are federal programs that provide disability benefits. We report on SSI/DI enrollment in a random sample of adult, long-term survivors of childhood cancer (n = 698) vs a comparison group without cancer (n = 210) from the Childhood Cancer Survivor Study who completed a health insurance survey. A total of 13.5% and 10.0% of survivors had ever been enrolled on SSI or DI, respectively, compared with 2.6% and 5.4% of the comparison group. Cranial radiation doses of 25 Gy or more were associated with a higher risk of current SSI (relative risk [RR] = 3.93, 95% confidence interval [CI] = 2.05 to 7.56) and DI (RR = 3.65, 95% CI = 1.65 to 8.06) enrollment. Survivors with severe/life-threatening conditions were more often enrolled on SSI (RR = 3.77, 95% CI = 2.04 to 6.96) and DI (RR = 2.73, 95% CI = 1.45 to 5.14) compared with those with mild/moderate or no health conditions. Further research is needed on disability-related financial challenges after childhood cancer. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Socioscientific Issues: A Path Towards Advanced Scientific Literacy and Improved Conceptual Understanding of Socially Controversial Scientific Theories

NASA Astrophysics Data System (ADS)

Pinzino, Dean William

This thesis investigates the use of socioscientific issues (SSI) in the high school science classroom as an introduction to argumentation and socioscientific reasoning, with the goal of improving students' scientific literacy (SL). Current research is reviewed that supports the likelihood of students developing a greater conceptual understanding of scientific theories as well as a deeper understanding of the nature of science (NOS), through participation in informal and formal forms of argumentation in the context of SSI. Significant gains in such understanding may improve a student's ability to recognize the rigor, legitimacy, and veracity of scientific claims and better discern science from pseudoscience. Furthermore, students that participate in significant SSI instruction by negotiating a range of science-related social issues can make significant gains in content knowledge and develop the life-long skills of argumentation and evidence-based reasoning, goals not possible in traditional lecture-based science instruction. SSI-based instruction may therefore help students become responsible citizens. This synthesis also suggests that that the improvements in science literacy and NOS understanding that develop from sustained engagement in SSI-based instruction will better prepare students to examine and scrutinize socially controversial scientific theories (i.e., evolution, global warming, and the Big Bang).

Comment on the Article by Thuillier et al. "The Infrared Solar Spectrum Measured by the SOLSPEC Spectrometer onboard the International Space Station". Invited Review

NASA Astrophysics Data System (ADS)

Weber, M.

2015-06-01

Thuillier et al. ( Solar Phys., 2015, DOI:10.1007/s11207-015-0704-1) discuss the apparent discrepancy between the ATLAS-3 composite solar spectral irradiances (SSI) covering the ultraviolet/visible/near-infrared (NIR) spectral region with more recent SSI measurements in the NIR. Recent measurements from IRSPERAD, CAVIAR, SCIAMACHY, SOLSPEC/ISS (the SOLAR2 spectrum from 2008), and unadjusted SIM show that above about 1600 nm, SSI is lower by about 8 % with respect to ATLAS-3. A new correction is presented in Thuillier et al. (2015) that leads to SOLSPEC/ISS (SOLAR2rev) which is in better agreement with ATLAS-3. SOLSPEC/ISS SSI underwent a +10 % change from 2008 to 2010, leading to better agreement with ATLAS-3, but it remains unclear which year provided the proper radiometric level, 2008 (SOLAR2) or 2010 (SOLAR2rev) as no link to pre-launch calibration is established. Before interpreting the NIR SSI observations using our current physical understanding (constraints by the total solar irradiance and solar models), the cause for the discrepancy between the early ATLAS-3 and all recent measurements (without a-posteriori adjustments) needs to be understood considering instrument and calibration performance alone.

Burden of Surgical Site Infections Associated with Arthroplasty and the Contribution of Staphylococcus aureus.

PubMed

Patel, Harshila; Khoury, Hanane; Girgenti, Douglas; Welner, Sharon; Yu, Holly

2016-02-01

Patients undergoing arthroplasty are at considerable risk of experiencing post-operative complications, including surgical site infections (SSIs). In addition to potential economic consequences, SSIs can have a negative impact on patient outcomes and may potentially be life-threatening. Staphylococcus aureus has been consistently shown as the leading cause of SSIs associated with orthopedic surgery, with an important contribution from methicillin-resistant S. aureus (MRSA). This study evaluated the global burden of SSIs among patients undergoing orthopedic surgical procedures, and specifically those undergoing knee and hip arthroplasties. An extensive search of PubMed and recent conference proceedings was conducted. English articles published between 2003 and 2013 pertaining to SSI epidemiology, patient outcomes, and healthcare resource utilization and costs were reviewed. Overall, 81 studies were included, mainly from North America and Europe. Median SSI and S. aureus SSI rates, calculated as percentage of all arthroplasty procedures, were 1.7% (range: 0.25%-4.4%; 15 studies) and 0.6% (range: 0.1%-23%), respectively. Median SSI rates were 1.3% (range: 0.05%-19%; 22 studies) after knee arthroplasty, and 2.1% (range: 0.05%-28%; 24 studies) after hip arthroplasty. S. aureus SSI rates ranged from 0.2%-2.4% and 0.18%-3.8% for patients undergoing knee and hip arthroplasty, respectively. The percentage of S. aureus SSIs because of MRSA varied widely within each patient category. SSI-related mortality data (14 studies) showed that in-hospital mortality rates were low (1.2%-2.5%), but increased with time after index arthroplasty procedure (up to 56% over 1 y). Studies assessing healthcare resource utilization (n = 21) revealed that developing post-orthopedic SSIs resulted in a two- to three-fold increase in length of hospital stay (LOS) compared with non-infected patients (median LOS: 18.9 d vs. 6 d for non-SSI patients). Patients with SSIs because of methicillin-resistant staphylococci incurred greater mean LOS compared with SSIs because of methicillin-sensitive organisms. Readmission rates reported in 11 studies indicate a greater likelihood in the presence of SSIs; comparison across studies was not feasible because of differences in data reporting. Consistent with increased healthcare resource utilization (LOS and readmission) associated with SSIs, cost studies (n = 23) revealed that the presence of SSIs was associated with up to three-fold cost increase compared with the absence of SSI across all orthopedic patient categories assessed. SSIs are associated with increased morbidity, mortality rates, healthcare resource utilization, and costs. Despite the relatively low SSI incidence following orthopedic surgery and specifically arthroplasty, preventive methods, specifically those targeting S. aureus, would serve to minimize costs and improve patient outcomes.

Topography within Europa's Mannann'an crater

NASA Technical Reports Server (NTRS)

1998-01-01

This three dimensional effect is created by superimposing images of Jupiter's icy moon, Europa, which were taken from slightly different perspectives. When viewed through red (left eye) and blue (right eye) filters, this product, a stereo anaglyph, shows variations in height of surface features.

This view shows the rim and interior of the impact crater Mannann'an, on Jupiter's moon Europa. The stereo image reveals the rim of the crater which appears as a tall ridge near the left edge of the image, as well as and numerous small hills on the bottom of the crater. One of the most striking features is the large pit surrounded by circular cracks on the right side of the image, with dark radiating fractures in its center.

The right (blue) image is a high resolution image (20 meters per picture element) taken through a clear filter. The left (red) image is composed of lower resolution (80 meters per picture element) color images taken through violet, green, and near-infrared filters and averaged to approximate an unfiltered view.

North is to the top of the picture and the sun illuminates the scene from the east (right). The image, centered at 3 degrees north latitude and 120 degrees west longitude, covers an area approximately 18 by 4 kilometers (11 by 2.5 miles). The finest details that can be discerned in this picture are about 40 meters (44 yards) across. The images were taken on March 29th, 1998 at 13 hours, 17 minutes, 29 seconds Universal Time at a range of 1934 kilometers by the Solid State Imaging (SSI) system on NASA's Galileo spacecraft.

The Jet Propulsion Laboratory, Pasadena, CA manages the Galileo mission for NASA's Office of Space Science, Washington, DC. JPL is an operating division of California Institute of Technology (Caltech).

This image and other images and data received from Galileo are posted on the World Wide Web, on the Galileo mission home page at URL http://galileo.jpl.nasa.gov. Background information and educational context for the images can be found at URL http://www.jpl.nasa.gov/galileo/sepo

Is hospital information system relevant to detect surgical site infection? Findings from a prospective surveillance study in posterior instrumented spinal surgery.

PubMed

Boetto, J; Chan-Seng, E; Lonjon, G; Pech, J; Lotthé, A; Lonjon, N

2015-11-01

Spinal instrumentation has a high rate of surgical site infection (SSI), but results greatly vary depending on surveillance methodology, surgical procedures, or quality of follow-up. Our aim was to study true incidence of SSI in spinal surgery by significant data collection, and to compare it with the results obtained through the hospital information system. This work is a single center prospective cohort study that included all patients consecutively operated on for spinal instrumentation by posterior approach over a six-month period regardless the etiology. For all patients, a "high definition" prospective method of surveillance was performed by the infection control (IC) department during at least 12 months after surgery. Results were then compared with findings from automatic surveillance though the hospital information system (HIS). One hundred and fifty-four patients were included. We found no hardly difference between "high definition" and automatic surveillance through the HIS, even if HIS tended to under-estimate the infection rate: rate of surgical site infection was 2.60% and gross SSI incidence rate via the hospital information system was 1.95%. Smoking and alcohol consumption were significantly related to a SSI. Our SSI rates to reflect the true incidence of infectious complications in posterior instrumented adult spinal surgery in our hospital and these results were consistent with the lower levels of published infection rate. In-house surveillance by surgeons only is insufficiently sensitive. Further studies with more patients and a longer inclusion time are needed to conclude if SSI case detection through the HIS could be a relevant and effective alternative method. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

Sorce Observations of Solar Cycles 23 and 24 - What's New? What's Next?

NASA Astrophysics Data System (ADS)

Cahalan, R. F.; Kopp, G.; Pilewskie, P.; Richard, E. C.; Woods, T. N.

2014-12-01

We discuss recent changes in estimates of the Total Solar Irradiance (TSI, formerly "solar constant") and the energy budget. This more accurate value of TSI implies a more accurate estimate of the Sun's luminosity, and lifetime. We highlight the historic closing of the calibration gap between the suite of TSI instruments, due largely to comparisons made with a cryogenic Transfer Radiometer Facility (TRF) located at the University of Colorado, built by UCO/LASP with support from NASA and NIST. The resulting continuous record of TSI promises to be a milestone in improving understanding of the Sun's impact on Earth's climate. Climate models are sensitive not only to TSI, but also to variations in the Spectral Solar Irradiance (SSI), and the vertical profiles of temperature and ozone are especially sensitive to SSI variations. Variations in SSI need further study before they may be considered as firmly established as TSI variations, which themselves remain controversial, despite a strengthening consensus over the SORCE epoch. The TSIS SIM has recently undergone comprehensive end-to-end calibration in the LASP SSI Radiometry Facility (SRF) utilizing the NIST SIRCUS laser system covering 210-2400 nm for SSI, a facility not yet available when SORCE launched in 2003. With SORCE follow-on missions such as the Total and Spectral Solar Irradiance Sensor (TSIS), we anticipate narrowing uncertainties in SSI variability that will be important to improving our understanding of the climate responses to solar forcing. The long-term goal of improving the ability to monitor Earth's energy balance, and the energy imbalance that drives global warming, will need continued improvements in the measurement of both shortwave solar and longwave earth-emitted radiation.

Prophylaxis of surgical site infection in adult spine surgery: A systematic review.

PubMed

Yao, Reina; Tan, Terence; Tee, Jin Wee; Street, John

2018-06-01

Surgical site infection (SSI) remains a significant source of morbidity in spine surgery, with reported rates varying from 0.7 to 16%. To systematically review and evaluate the evidence for strategies for prophylaxis of SSI in adult spine surgery in the last twenty years. Two independent systematic searches were conducted, at two international spine centers, encompassing PubMed, ClinicalTrials.gov, Cochrane Database, EBSCO Medline, ScienceDirect, Ovid Medline, EMBASE (Ovid), and MEDLINE. References were combined and screened, then distilled to 69 independent studies for final review. 11 randomized controlled trials (RCTs), 51 case-controlled studies (CCS), and 7 case series were identified. Wide variation exists in surgical indications, approaches, procedures, and even definitions of SSI. Intra-wound vancomycin powder was the most widely studied intervention (19 studies, 1 RCT). Multiple studies examined perioperative antibiotic protocols, closed-suction drainage, povidone-iodine solution irrigation, and 2-octyl-cyanoacrylate skin closure. 18 interventions were examined by a single study only. There is limited evidence for the efficacy of intra-wound vancomycin. There is strong evidence that closed-suction drainage does not affect SSI rates, while there is moderate evidence for the efficacy of povidone-iodine irrigation and that single-dose preoperative antibiotics is as effective as multiple doses. Few conclusions can be drawn about other interventions given the paucity and poor quality of studies. While a small body of evidence underscores a select few interventions for SSI prophylaxis in adult spine surgery, most proposed measures have not been investigated beyond a single study. Further high level evidence is required to justify SSI preventative treatments. Copyright © 2018 Elsevier Ltd. All rights reserved.

Antibiotic and Duration of Perioperative Prophylaxis Predicts Surgical Site Infection in Head and Neck Surgery.

PubMed

Langerman, Alexander; Thisted, Ronald; Hohmann, Samuel; Howell, Michael

2016-06-01

To examine the effect of giving antibiotics on the day of surgery (DOS) vs DOS and first postoperative day (DOS+1) for prophylaxis against surgical site infection (SSI) in clean-contaminated head and neck surgery (CCHNS). Retrospective multi-institution analysis using University HealthSystem Consortium data. A multivariate logistic regression model of 8836 discharge records from patients undergoing CCHNS was used to determine the odds of SSI for antibiotic agent/duration combinations. Ninety-two academic and affiliated medical centers from 2008 to 2011. Ampicillin/sulbactam, clindamycin, cefazolin + metronidazole, and cefazolin alone were the most common antibiotics. For patients receiving antibiotics only on DOS, there was no significant difference in odds of SSI based on antibiotic choice. When given on the DOS and DOS+1, patients receiving ampicillin/sulbactam had a reduction in odds of SSI by over two-thirds (odds ratio [OR], 0.28 [95% confidence interval, 0.13-0.61], P = .001, compared with ampicillin/sulbactam on DOS only), whereas this effect was not seen with clindamycin (1.82 [0.93-3.56], P = .078, compared with clindamycin on DOS only). Prolonging clindamycin beyond the DOS was associated with a higher odds of SSI compared with DOS-only ampicillin/sulbactam (OR, 2.66; 95% CI, 1.33-5.30; P = .006). These relationships held in a subset of physicians and hospitals that used multiple different regimens. DOS+1 regimens were not associated with an increased odds of antibiotic-induced complications. Prolonging ampicillin/sulbactam beyond the day of surgery may have a protective effect against SSI, and 1 or more days of ampicillin/sulbactam may be preferable to multiple days of clindamycin. New randomized trials are needed to define the ideal regimen for CCHNS. © American Academy of Otolaryngology—Head and Neck Surgery Foundation 2016.

Antimicrobial prophylaxis to prevent surgical site infection in adolescent idiopathic scoliosis patients undergoing posterior spinal fusion: 2 doses versus antibiotics till drain removal.

PubMed

Kamath, Vijay H D; Cheung, Jason Pui Yin; Mak, Kin Cheung; Wong, Yat Wa; Cheung, Wai Yuen; Luk, Keith Dip Kei; Cheung, Kenneth Man Chee

2016-10-01

There is much variation in the choice, timing and duration of antimicrobial prophylaxis for preventing surgical site infections (SSI) but no guideline exists for scoliosis surgery. The aim of study was to compare the efficacy of two antimicrobial prophylaxis (AMP) protocols with cephazolin in preventing SSI in adolescent idiopathic scoliosis (AIS). A retrospective comparative analysis of two post-operative AMP protocols (two postoperative doses versus continued antibiotics till drain removal) was performed. Patient characteristics, pre-operative, intra- and post-operative risk factors for infection, drain use, generic drug name and number of doses administered were recorded from 226 patients with AIS who had undergone posterior spinal fusion. Details of superficial or deep SSI and wound healing aberrations, and serious adverse events were recorded. Analysis was performed to evaluate differences in the pre-, intra- and post-operative variables between the two groups. 155 patients received 2 postoperative doses of AMP and 71 patients had antibiotics till drain removal. The average follow-up was 43 months. The overall rate of SSI was 1.7 % for the spine wound and 1.3 % for the iliac crest wound. 1.9 % of patients with 2 doses of AMP and 1.4 % of patients with antibiotics till drain removal had SSI. No adverse reactions attributable to cephazolin were observed. This is the first study on the AMP protocol in scoliosis surgery for SSI prevention. Results suggest that two doses of AMP are as effective as continued antimicrobial use until drain removal. Cephazolin appears to be effective and safe for prophylaxis.

Surveillance, control, and prevention of surgical site infections in breast cancer surgery: a 5-year experience.

PubMed

Vilar-Compte, Diana; Rosales, Samuel; Hernandez-Mello, Norma; Maafs, Eduardo; Volkow, Patricia

2009-10-01

We analyzed variations in surgical site infections (SSIs) during 5 years of a prospective surveillance program and investigated possible contributors to SSIs in a cohort of patients who underwent surgery for breast cancer. All breast surgeries performed between January 2001 and December 2005 were registered. Patients were followed-up by direct observation for at least 30 days under standardized conditions. The main outcome studied was SSI. A case-control analysis was conducted to identify SSI-associated risk factors and to evaluate SSI variations by means of a control chart. During the study period, a total of 2338 breast cancer surgeries were recorded, and 441 SSIs (18.9%) were diagnosed. SSI frequency varied across the 5-year period, with a sharp decline seen after the introduction of preventive policies. After 2002, 3 out-of-confidence limits of SSIs were observed, 2 related to the use of evacuation systems and 1 associated with a group of rotating residents. Concomitant preoperative chemoradiation (odds ratio [OR]=3.47; 95% confidence interval [CI]=2.51 to 4.80), hematoma (OR=3.05; 95% CI=1.70 to 5.52), age > or = 58 years (OR=1.83; 95% CI=1.27 to 2.65), body mass index > or = 30.8 (OR=1.58; 95% CI=1.14 to 2.18), and duration of surgery > or = 160 minutes (OR=1.73; 95% CI=1.20 to 2.50) were found to be SSI-associated risk factors. After 5 years of a continuous prospective surveillance program, we were able to decrease the rate of SSIs in patients undergoing breast cancer surgery (from 33.3% in 2000 to 18.9% in 2005), identify SSI-associated risk factors, and improve the quality of care delivered to these patients.

Efficacy of prophylactic antibiotic administration for breast cancer surgery in overweight or obese patients: a randomized controlled trial.

PubMed

Gulluoglu, Bahadir M; Guler, Sertac Ata; Ugurlu, M Umit; Culha, Gulcan

2013-01-01

To assess the impact of prophylactic antibiotics on the prevention of surgical site infection (SSI) and the cost-effectiveness of this prophylaxis for breast cancer surgery in overweight or obese women. SSI is higher than expected after breast surgery. Obesity was found to be one of the risk factors. The trial was designed as a phase IV randomized, controlled, parallel-group efficacy trial. It was conducted at a tertiary university hospital. Overweight or obese women with clinically early-stage breast cancer who had been assigned to undergo surgery were eligible. Patients were randomly allocated to either a prophylaxis or a control group by using a computer-generated list. The prophylaxis group received 1 g ampicillin-sulbactam intravenously at anesthesia. The control group received no intervention. Patients and observers were blinded to the assignments. The primary outcome was the comparison of SSI incidences of the 2 groups. Patients were monitored for 30 days. A total of 369 patients were included in final analysis, out of which 187 were allocated for prophylaxis and 182 were randomly assigned to the control group. Analysis was done according to the intention-to-treat principle. Prophylaxis significantly reduced the SSI rate (4.8%) in the prophylaxis group when compared with that in the control group [13.7%; relative risk (RR) 0.35; 95% CI: 0.17-0.73]. No adverse reaction was observed. The mean SSI-related cost (20.26 USD) was found to be significantly higher in the control group when compared with that (8.48 USD) in the prophylaxis group. Antibiotic prophylaxis significantly decreased SSI incidence after elective surgery and was shown to be cost-effective in obese breast cancer patients. ClinicalTrials.gov Identifier: NCT00356148.

Suture, synthetic, or biologic in contaminated ventral hernia repair.

PubMed

Bondre, Ioana L; Holihan, Julie L; Askenasy, Erik P; Greenberg, Jacob A; Keith, Jerrod N; Martindale, Robert G; Roth, J Scott; Liang, Mike K

2016-02-01

Data are lacking to support the choice between suture, synthetic mesh, or biologic matrix in contaminated ventral hernia repair (VHR). We hypothesize that in contaminated VHR, suture repair is associated with the lowest rate of surgical site infection (SSI). A multicenter database of all open VHR performed at from 2010-2011 was reviewed. All patients with follow-up of 1 mo and longer were included. The primary outcome was SSI as defined by the Centers for Disease Control and Prevention. The secondary outcome was hernia recurrence (assessed clinically or radiographically). Multivariate analysis (stepwise regression for SSI and Cox proportional hazard model for recurrence) was performed. A total of 761 VHR were reviewed for a median (range) follow-up of 15 (1-50) mo: there were 291(38%) suture, 303 (40%) low-density and/or mid-density synthetic mesh, and 167(22%) biologic matrix repair. On univariate analysis, there were differences in the three groups including ethnicity, ASA, body mass index, institution, diabetes, primary versus incisional hernia, wound class, hernia size, prior VHR, fascial release, skin flaps, and acute repair. The unadjusted outcomes for SSI (15.1%; 17.8%; 21.0%; P = 0.280) and recurrence (17.8%; 13.5%; 21.5%; P = 0.074) were not statistically different between groups. On multivariate analysis, biologic matrix was associated with a nonsignificant reduction in both SSI and recurrences, whereas synthetic mesh associated with fewer recurrences compared to suture (hazard ratio = 0.60; P = 0.015) and nonsignificant increase in SSI. Interval estimates favored biologic matrix repair in contaminated VHR; however, these results were not statistically significant. In the absence of higher level evidence, surgeons should carefully balance risk, cost, and benefits in managing contaminated ventral hernia repair. Copyright © 2016 Elsevier Inc. All rights reserved.

Is There Room for Prevention? Examining the Effect of Outpatient Facility Type on the Risk of Surgical Site Infection.

PubMed

Parikh, Rishi; Pollock, Daniel; Sharma, Jyotirmay; Edwards, Jonathan

2016-10-01

OBJECTIVE We compared risk for surgical site infection (SSI) following surgical breast procedures among 2 patient groups: those whose procedures were performed in ambulatory surgery centers (ASCs) and those whose procedures were performed in hospital-based outpatient facilities. DESIGN Cohort study using National Healthcare Safety Network (NHSN) SSI data for breast procedures performed from 2010 to 2014. METHODS Unconditional multivariate logistic regression was used to examine the association between facility type and breast SSI, adjusting for American Society of Anesthesiologists (ASA) Physical Status Classification, patient age, and duration of procedure. Other potential adjustment factors examined were wound classification, anesthesia use, and gender. RESULTS Among 124,021 total outpatient breast procedures performed between 2010 and 2014, 110,987 procedure reports submitted to the NHSN provided complete covariate data and were included in the analysis. Breast procedures performed in ASCs carried a lower risk of SSI compared with those performed in hospital-based outpatient settings. For patients aged ≤51 years, the adjusted risk ratio was 0.36 (95% CI, 0.25-0.50) and for patients >51 years old, the adjusted risk ratio was 0.32 (95% CI, 0.21-0.49). CONCLUSIONS SSI risk following breast procedures was significantly lower among ASC patients than among hospital-based outpatients. These findings should be placed in the context of study limitations, including the possibility of incomplete ascertainment of SSIs and shortcomings in the data available to control for differences in patient case mix. Additional studies are needed to better understand the role of procedural settings in SSI risk following breast procedures and to identify prevention opportunities. Infect Control Hosp Epidemiol 2016;1-7.

Implementation of Preoperative Screening Criteria Lowers Infection and Complication Rates Following Elective Total Hip Arthroplasty and Total Knee Arthroplasty in a Veteran Population.

PubMed

Nussenbaum, Fernando D; Rodriguez-Quintana, David; Fish, Sara M; Green, David M; Cahill, Catherine W

2018-01-01

Total hip arthroplasty (THA) and total knee arthroplasty (TKA) are common procedures with a risk of complications. Attempting to minimize complications, our institution implemented preoperative screening criteria for patients undergoing elective total joint replacement. Our study aimed to determine if screening criteria lowered total complications and/or surgical site infections (SSI). Two groups of consecutive patients undergoing TKA and THA at a single Veterans Affairs facility were evaluated prior to and after implementation of screening criteria, 520 and 475 respectively. Screening criteria included hemoglobin A1c ≤7, hemoglobin ≥11, body mass index ≤35, and albumin ≥3.5. Groups were analyzed for demographics, preoperative comorbidities, and postoperative complications. Rates of total complications and SSI were compared. Average follow-up was at least 2 years with minimum of 1 year. Demographics and comorbidities outside the screening criteria were similar. Total complication rate was reduced from 35.4% to 14.8% (P < .01) after implementation of screening criteria. For TKA, total complications were reduced from 33.1% to 15.0% (P < .01) and for THA they were reduced from 42.4% to 14.2% (P < .01). SSI rates for combined TKA and THA were reduced from 4.4% to 1.3% (P < .01). For knees, SSI was reduced from 4.6% to 1.3% (P = .01) and was statistically significant. For THA, SSI decreased from 3.8% to 1.2% (P < .05). Our institution saw a statistically significant decrease in both SSI and total complications following implementation of preoperative screening criteria for elective TKA and THA. Published by Elsevier Inc.

Does surgical site infection after Caesarean section in Polish hospitals reflect high-quality patient care or poor postdischarge surveillance? Results from a 3-year multicenter study.

PubMed

Różańska, Anna; Jarynowski, Andrzej; Kopeć-Godlewska, Katarzyna; Wójkowska-Mach, Jadwiga; Misiewska-Kaczur, Agnieszka; Lech, Marzena; Rozwadowska, Małgorzata; Karwacka, Marlena; Liberda, Joanna; Domańska, Joanna

2018-01-01

Caesarean sections (CSs) are associated with a high infection risk. Surgical site infection (SSI) incidence is among the markers of effectiveness of infection prevention efforts. The aim of this study was to analyze risk factors for SSI, incidence, and microbiology in patients who underwent CS. The study was conducted during 2013-2015 using active infection surveillance in 5 Polish hospitals according to the European Centre for Disease Prevention and Control surveillance network known as HAI-Net. For each procedure, the following data were registered: age, American Society of Anesthesiologists score, procedure time, elective or emergency procedure, use of perioperative antibiotic prophylaxis, microbiology, the treatment used, and other information. SSI incidence was 0.5% and significant differences were noted among hospitals (between 0.1% and 1.8%), for different American Society of Anesthesiologists scales (between 0.2% and 4.8%) and different values of standardized SSI risk index (between 0.0% and 0.8%). In 3.1% of procedures, with no antibiotic prophylaxis, SSI risk was significantly higher. Deep infections dominated: 61.5% with superficial infections in only approximately 30% of cases and 2.6% of infections were detected postdischarge without readmissions. Results showed high incidence of SSI in Poland without perioperative antibiotic prophylaxis, and secondly, ineffective surveillance according to CS status, considering outpatient obstetric care. Without postdischarge surveillance, it is not possible to recognize the epidemiologic situation, and further, to set priorities and needs when it comes to infection prophylaxis, especially because such low incidence may indicate no need for improvement in infection control. Copyright © 2018 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

A retrospective study of antibiotic prophylaxis value in surgical treatment of lower limb fracture.

PubMed

Bandalović, Ante; Zindović, Antonija; Boschi, Vladimir; Bakota, Bore; Marinović, Marin; Čoklo, Miran; Rošin, Matko; Parać, Zlatko; Čukelj, Fabijan

2015-11-01

Surgical site infections (SSI) are nosocomial infections that cause considerable problems in orthopaedic surgery. Antibiotic prophylaxis can be used to reduce the risk for SSI. There is no universal antibiotic that can be recommended for prophylaxis in terms of coverage of all possible pathogens because of antibiotic resistance, and there are no universal recommendations for different types of patients in terms of injury type, selected operation and risk factors for development of SSI. The aim of this study was to analyse the effectiveness of antibiotic prophylaxis in surgical treatment (ORIF) of closed lower limb fractures in young, healthy patients. Patient details were collected from the patient histories. Inclusion criteria for participants were age 20-30 years, not suffering from any type of chronic disease or state that may affect postoperative infection and ISS≤9. Antibiotic prophylaxis use and outcome (SSI) were compared between two groups of patients. Data were analysed using descriptive statistics, Fisher's exact test and t-test for proportions. A total of 347 patients with closed lower limb fractures treated with ORIF met the inclusion criteria. There were 290 male and 57 female patients, with an average age of 24.47 years. Prophylactic antibiotics were given to 242 patients (69.74%); 2g ceftriaxone was administered to 88.02% of the patients who received antibiotic prophylaxis. Ten patients developed postoperative infection (eight out of 242 with antibiotic prophylaxis and two out of 105 without antibiotic prophylaxis). The difference between the two groups was not statistically significant (Fisher's exact test, P=0.749). Antibiotic prophylaxis was ineffective in preventing SSI in patients with no risk factors for SSI who were undergoing ORIF for closed lower limb fractures. Copyright © 2015 Elsevier Ltd. All rights reserved.

Galileo imaging observations of Lunar Maria and related deposits

NASA Astrophysics Data System (ADS)

Greeley, Ronald; Kadel, Steven D.; Williams, David A.; Gaddis, Lisa R.; Head, James W.; McEwen, Alfred S.; Murchie, Scott L.; Nagel, Engelbert; Neukum, Gerhard; Pieters, Carle M.; Sunshine, Jessica M.; Wagner, Roland; Belton, Michael J. S.

The Galileo spacecraft imaged parts of the western limb and far side of the Moon in December 1990. Ratios of 0.41/0.56 μm filter images from the Solid State Imaging (SSI) experiment provided information on the titanium content of mare deposits; ratios of the 0.76/0.99 μm images indicated 1 μm absorptions associated with Fe2+ in mafic minerals. Mare ages were derived from crater statistics obtained from Lunar Orbiter images. Results on mare compositions in western Oceanus Procellarum and the Humorum basin are consistent with previous Earth-based observations, thus providing confidence in the use of Galileo data to extract compositional information. Mare units in the Grimaldi and Riccioli basins range in age from 3.25 to 3.48 Ga and consist of medium- to medium-high titanium (<4 to 7% TiO2) content lavas. The Schiller-Zucchius basin shows a higher 0.76/0.99 μm ratio than the surrounding highlands, indicating a potentially higher mafic mineral content consistent with previous interpretations that the area includes mare deposits blanketed by highland ejecta and light plains materials. The oldest mare materials in the Orientale basin occur in south-central Mare Orientale and are 3.7 Ga old; youngest mare materials are in Lacus Autumni and are 2.85 Ga old; these units are medium- to medium-high titanium (<4 to 7% TiO2) basalts. Thus, volcanism was active in Orientale for 0.85 Ga, but lavas were relatively constant in composition. Galileo data suggest that Mendel-Rydberg mare is similar to Mare Orientale; cryptomare are present as well. Thus, the mare lavas on the western limb and far side (to 178°E) are remarkably uniform in composition, being generally of medium- to medium-high titanium content and having relatively low 0.76/0.99 μm ratios. This region of the Moon is between two postulated large impact structures, the Procellarum and the South Pole-Aitken basins, and may have a relatively thick crust. In areas underlain by an inferred thinner crust, i.e., zones within large basins (as at Apollo), titanium content is often higher. However, no mare deposits with titanium abundances approaching those of the high-titanium (9 to 14% TiO2) Apollo 11 and 17 basalts nor of the high-titanium regions of central Oceanus Procellarum are seen on the western limb or eastern far side. Light plains deposits are generally indistinct from the surrounding highlands in the SSI data and are inferred to be derived primarily from the same material that forms the highlands. Some of the light plains are too young to be related to basin-forming impacts, suggesting possible volcanic origin. Dark mantle deposit compositions derived from SSI data are consistent with Earth-based observations of similar near-side deposits and are interpreted to be pyroclastic materials. However, the moderate albedo and 1 μm absorption of the dark mantle deposit on the southwest margin of the Orientale basin suggest it is a local pyroclastic deposit contaminated with underlying highland materials from the Orientale impact.

SSI/MSI/LSI/VLSI/ULSI.

ERIC Educational Resources Information Center

Alexander, George

1984-01-01

Discusses small-scale integrated (SSI), medium-scale integrated (MSI), large-scale integrated (LSI), very large-scale integrated (VLSI), and ultra large-scale integrated (ULSI) chips. The development and properties of these chips, uses of gallium arsenide, Josephson devices (two superconducting strips sandwiching a thin insulator), and future…

76 FR 60755 - Air Cargo Screening; Reopening of Comment Period

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-30

... activities, the disclosure of which would constitute an unwarranted invasion of privacy, reveal trade secrets... secrets, confidential commercial or financial information, or SSI to the public regulatory docket. Please.... TSA will hold documents containing SSI, confidential business information, or trade secrets in a...

Risk factors associated with surgical site infection and the development of short-term complications in macaques undergoing indwelling vascular access port placement.

PubMed

Graham, M L; Rieke, E F; Wijkstrom, M; Dunning, M; Aasheim, T C; Graczyk, M J; Pilon, K J; Hering, B J

2008-08-01

Risk factors associated with surgical site infection (SSI) and the development of short-term complications in macaques undergoing vascular access port (VAP) placement are evaluated in this study. Records from 80 macaques with VAPs were retrospectively reviewed. Logistic regression was used to identify factors associated with short-term post-operative complications. The primary outcome was SSI, which occurred in 21.6% (52.6% in the first 12 months vs. 13% thereafter) of procedures. SSI was associated with major secondary complications including VAP removal (11.4%), wound dehiscence (5.7%), and mechanical catheter occlusion (5.7%). In multivariate modeling, only surgical program progress was a statistically significant predictor of SSI, while animal compliance had a slightly protective effect. Vascular access ports have a moderate risk of complications, provided the surgical program optimizes best practices. Under complex experimental conditions, VAPs represent an important refinement, both improving animals' overall well-being and environment and reducing stress.

Elderly Immigrants' Labor Supply Response to Supplemental Security Income.

PubMed

Kaushal, Neeraj

2010-01-01

This paper examined how the 1996 Personal Responsibility and Work Opportunity Reconciliation Act, which banned Supplemental Security Income to the majority of elderly immigrants, affected their employment, retirement, and family incomes. The policy was found to be associated with a 3.5 percentage point (9.5 percent) increase in the employment and a 3.8 percentage point (7 percent) decrease in the retirement of foreign-born elderly men. Partly as a result of their employment response, SSI ineligibility and the consequent decline in SSI receipt did not have any statistically significant effects on the family incomes of elderly foreign-born men. Noncitizen elderly women, on the other hand, did not experience any increase in employment, and those without family support suffered a 10 to 17 percent decline in income. These findings suggest that access to SSI did not create work disincentives for noncitizen elderly women and that SSI restrictions have imposed financial hardship on those without any family support, many of whom perhaps cannot effectively increase their employment.

Plastic freezer bags: a cost-effective method to protect extraction sites in laparoscopic colorectal procedures?

PubMed

Huynh, Hai P; Musselman, Reilly P; Trottier, Daniel C; Soto, Claudia M; Poulin, Eric C; Mamazza, Joseph; Boushey, Robin P; Auer, Rebecca C; Moloo, Husein

2013-10-01

To review surgical-site infection (SSI) and retrieval-site tumor recurrence rates in laparoscopic colorectal procedures when using a plastic freezer bag as a wound protector. Laparoscopic colorectal procedures where a plastic freezer bag used as a wound protector at the extraction site were reviewed between 1991 and 2008 from a prospectively collected database. χ test was used to compare SSI and tumor recurrence rates between groups. Costing data were obtained from the operating room supplies department. A total of 936 cases with 51 (5.45%) surgical-site infections were identified. SSI rates did not differ when comparing groups based on demographic factors, diagnosis, or location of procedure. Retrieval-site tumor recurrence rate was 0.21% (1/474). Cost of plastic freezer bags including sterilization ranged from $0.25 to $3. Plastic freezer bags as wound protectors in laparoscopic colorectal procedures are cost effective and have SSI and retrieval-site tumor recurrence rates that compare favorably to published data.

Seasonal Variations in the Risk of Reoperation for Surgical Site Infection Following Elective Spinal Fusion Surgery: A Retrospective Study Using the Japanese Diagnosis Procedure Combination Database.

PubMed

Ohya, Junichi; Chikuda, Hirotaka; Oichi, Takeshi; Kato, So; Matsui, Hiroki; Horiguchi, Hiromasa; Tanaka, Sakae; Yasunaga, Hideo

2017-07-15

A retrospective study of data abstracted from the Diagnosis Procedure Combination (DPC) database, a national representative database in Japan. The aim of this study was to examine seasonal variations in the risk of reoperation for surgical site infection (SSI) following spinal fusion surgery. Although higher rates of infection in the summer than in other seasons were thought to be caused by increasing inexperience of new staff, high temperature, and high humidity, no studies have examined seasonal variations in the risk of SSI following spinal fusion surgery in the country where medical staff rotation timing is not in summer season. In Japan, medical staff rotation starts in April. We retrospectively extracted the data of patients who were admitted between July 2010 and March 2013 from the DPC database. Patients were included if they were aged 20 years or older and underwent elective spinal fusion surgery. The primary outcome was reoperation for SSI during hospitalization. We performed multivariate analysis to clarify the risk factors of primary outcome with adjustment for patient background characteristics. We identified 47,252 eligible patients (23,659 male, 23,593 female). The mean age of the patients was 65.4 years (range, 20-101 yrs). Overall, reoperation for SSI occurred in 0.93% of the patients during hospitalization. The risk of reoperation for SSI was significantly higher in April (vs. February; odds ratio, 1.93; 95% confidence interval, 1.09-3.43, P = 0.03) as well as other known risk factors. In subgroup analysis with stratification for type of hospital, month of surgery was identified as an independent risk factor of reoperation for SSI among cases in an academic hospital, although there was no seasonal variation among those in a nonacademic hospital. This study showed that month of surgery is a risk factor of reoperation for SSI following elective spinal fusion surgery, nevertheless, in the country where medical staff rotation timing is not in summer season. 3.

A retrospective analysis of the risk factors for surgical site infections and long-term follow-up after transpalpebral enucleation in horses.

PubMed

Huppes, Tsjester; Hermans, Hanneke; Ensink, Jos M

2017-06-02

Implants are often used to improve the cosmetic appearance of horses after enucleation of the eye. When surgical site infection (SSI) occurs, the implant will almost always be lost. The aim of this study is to collect data on the risk factors for SSIs and report long-term follow-up (cosmetic results and return to work) after transpalpebral enucleations. In this retrospective study, records of horses undergoing transpalpebral enucleation were reviewed (2007-2014) and telephone interviews were used to obtain long term follow-up. The potential risk factors for SSIs (indication for enucleation, use of an implant, standing procedures, duration of surgery, opening of the conjunctival sac and prolonged use of antimicrobials) were analysed for their association with the outcome measure 'SSI' vs 'no SSI' by multivariable binary logistic regression testing. Indications for enucleation were grouped as follows: Group 1 (clean) included equine recurrent uveitis, too small or too large globes, and intraocular tumours, Group 2 (non-clean) included corneal perforation/rupture and infected ulcers and Group 3 (tumour) included extraocular tumours. One hundred and seven cases of enucleation were evaluated. An implant was used in 49 horses. The overall number of SSIs was 8 (7.5%). Multivariable logistic regression testing showed implants (OR 7.5, P = 0.04) and standing procedures (OR 12.1; P = 0.03) were significantly associated with the percentage of SSIs and increased the risk of SSI. The eyes of horses in Groups 2 and 3 trended towards a larger risk for developing SSIs (OR 4.9; P = 0.09 and OR 5.9; P = 0.1, respectively). Prolonged use of antimicrobials, long surgery times and the opening of the conjunctival sac during dissection did not show significant associations with SSI risk. The risk of SSI after enucleation is low in clean eyes and when no implant is used. Placing an implant or performing a standing enucleation significantly increases the risk of SSIs. Although implants can be used for eyes that fall into Groups 2 and 3, 17% of the horses in these two groups developed an SSI leading to loss of the implant.

Teacher candidates' beliefs about including socioscientific issues in physics and chemistry

NASA Astrophysics Data System (ADS)

Barrett, Sarah Elizabeth

Teaching science for social justice involves a deliberate effort to reconstruct society into something more equitable and just. Introducing socioscientific issues (SSI) into science is one strategy toward this end. However, research indicates that SSI are rarely discussed in the physical sciences even though they exist. This may be due to the beliefs of chemistry and physics teachers with respect to what belongs in these subjects. If we wish to begin to influence these beliefs through initial teacher education, it is essential for teacher educators to understand the origins of these beliefs. In this qualitative study 12 teacher candidates were interviewed at 3 points during a 9 month teacher education program: at the beginning of the course (in September), after the first practicum (in November) and after the second practicum (in March). Teacher candidates' beliefs did not change significantly from the beginning of the study to the end. They displayed varying degrees of commitment to including SSI in their teaching. Based on their (a) conception of the ethics of science, (b) goals for science education, (c) idea of the place of ethics in science (education), and (d) beliefs about including SSI, the teacher candidates were divided into four groups. Four archetypes were derived: "Model Scientist/Engineer", "Model Individual", "Model Teacher", and "Model Citizen". Since these groups are archetypes, none of the participants fits into the categories perfectly but individual teacher candidates demonstrated more characteristics of one archetype than others. Only the 3 Model Citizens were committed to including SSI in their teaching while the others placed the priority on preparing students for the next level of schooling. A model was developed to serve as a microgeneology of teacher candidates' beliefs about including SSI in their teaching. It traced their beliefs from (a) life experiences to (b) conception of ethics and nature of science to (c) goals for science education to (d) inclusion or non-inclusion of SSI. Based on the archetypes, current beliefs were extrapolated into future beliefs. How teacher educators could use this model to influence the future beliefs of their students is discussed.

The Relationship between Social Support and Diet Quality in Middle-Aged and Older Adults in the United States.

PubMed

Pieroth, Renee; Rigassio Radler, Diane; Guenther, Patricia M; Brewster, Philip J; Marcus, Andrea

2017-08-01

Social support has been associated with physical and mental health; however, the relationship between social support and diet quality is not well understood. The purpose of this research was to assess the relationship between social support and overall diet quality among US adults. This study was a secondary analysis of data from adults aged 40 years and older who participated in the cross-sectional 2007-2008 National Health and Nutrition Examination Survey (N=3,243). Social support was determined by a modification of the Rees Social Support Index (SSI), which is the sum of five dichotomized variables addressing emotional support, financial support, marital status, close friends, and religious service attendance. Overall diet quality was measured by the Healthy Eating Index-2010 (HEI-2010) and calculated from the mean of two 24-hour dietary recalls. SAS survey procedures were used to incorporate the appropriate sample design weights. Unweighted frequencies are reported along with weighted means and standard errors (SE). Multivariable linear regression was used to compare the total HEI-2010 scores among the six SSI groups with additional models controlling for sex, age, race/ethnicity, income level, and education level, and stratifying by sex. In an unadjusted model, the mean total HEI-2010 score for those with an SSI score of 0 (n=37) was 50.0 (SE=2.83) compared to 57.1 (SE=0.89) for those with SSI score of 5 (n=676) (P<0.0001). The results were no longer statistically significant when adjusted for age, sex, race/ethnicity, income, and education level (P=0.14). However, when stratified by sex and adjusted for other demographics, higher SSI scores were associated with higher HEI-2010 scores compared to lower SSI scores in men (P=0.02), but there was no significant difference among SSI scores and HEI-2010 scores in women (P=0.43). This study suggests a positive relationship between social support and overall diet quality among middle-aged and older men, but not women, in the United States. Copyright © 2017 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

MarsQuest: Bringing the Excitement of Mars Exploration to the Public

NASA Astrophysics Data System (ADS)

Dusenbery, P. B.; Morrow, C. A.; Harold, J. B.; Klug, S. L.

2002-12-01

We are living in an extraordinary era of Mars exploration. NASA's Odyssey spacecraft has recently discovered vast amounts of hydrogen beneath the surface of Mars, suggesting the presence of sub-surface ice. Two Mars Exploration Rovers are scheduled to land in early 2004. To bring the excitement and discoveries of Mars exploration to the public, the Space Science Institute (SSI) of Boulder, CO, has developed a comprehensive Mars Education Program that includes: 1) large and small traveling exhibits, 2) workshops for museum and classroom educators (in partnership with the Mars Education Program at Arizona State University (ASU)), and 3) an interactive Website called MarsQuest Online (in partnership with TERC and JPL). All three components will be presented and offered as a good model for actively involving scientists and their discoveries to improve science education in museums and the classroom. The centerpiece of SSI's Mars Education Program is the 5,000-square-foot traveling exhibition, MarsQuest: Exploring the Red Planet, which was developed with support from the National Science Foundation (NSF), NASA, and several corporate donors. The MarsQuest exhibit is nearing the end of a highly successful, fully-booked three-year tour. The Institute plans to send an enhanced and updated MarsQuest on a second three-year tour and is also developing Destination: Mars, a mini-version of MarsQuest designed for smaller venues. Workshops for museum educators, docents, and local teachers are conducted at host sites. These workshops were developed collaboratively by Dr. Cheri Morrow, SSI's Education and Public Outreach Manager, and Sheri Klug, Director of the Mars K-12 Education Program at ASU. They are designed to inspire and empower participants to extend the excitement and science content of the exhibitions into classrooms and museum-based education programs in an ongoing fashion. The MarsQuest Online project is developing a Website that will use the MarsQuest exhibit as a context for online interactives that delve deeper into Mars science. This project, supported by NSF, will explore the potential for in-depth, Web-based studies that extend museum exhibit content onto the Web.

MarsQuest: Bringing the Excitement of Mars Exploration to the Public

NASA Astrophysics Data System (ADS)

Dusenbery, P. B.; Morrow, C. A.; Harold, J. B.; Klug, S. L.

2002-09-01

We are living in an extraordinary era of Mars exploration. NASA's Odyssey spacecraft has recently discovered vast amounts of hydrogen beneath the surface of Mars, suggesting the presence of sub-surface ice. Two Mars Exploration Rovers are scheduled to land in early 2004. To bring the excitement and discoveries of Mars exploration to the public, the Space Science Institute (SSI) of Boulder, CO, has developed a comprehensive Mars Education Program that includes: 1) large and small traveling exhibits, 2) workshops for museum and classroom educators (in partnership with the Mars Education Program at Arizona State University (ASU)), and 3) an interactive Website called MarsQuest Online (in partnership with TERC and JPL). All three components will be presented and offered as a good model for actively involving scientists and their discoveries to improve science education in museums and the classroom. The centerpiece of SSI's Mars Education Program is the 5,000-square-foot traveling exhibition, MarsQuest: Exploring the Red Planet, which was developed with support from the National Science Foundation (NSF), NASA, and several corporate donors. The MarsQuest exhibit is nearing the end of a highly successful, fully-booked three-year tour. The Institute plans to send an enhanced and updated MarsQuest on a second three-year tour and is also developing Destination: Mars, a mini-version of MarsQuest designed for smaller venues. Workshops for museum educators, docents, and local teachers are conducted at host sites. These workshops were developed collaboratively by Dr. Cheri Morrow, SSI's Education and Public Outreach Manager, and Sheri Klug, Director of the Mars K-12 Education Program at ASU. They are designed to inspire and empower participants to extend the excitement and science content of the exhibitions into classrooms and museum-based education programs in an ongoing fashion. The MarsQuest Online project is developing a Website that will use the MarsQuest exhibit as a context for online interactives that delve deeper into Mars science. This project, supported by NSF, will explore the potential for in-depth, Web-based studies that extend museum exhibit content onto the Web.

Software aspects of the Geant4 validation repository

NASA Astrophysics Data System (ADS)

Dotti, Andrea; Wenzel, Hans; Elvira, Daniel; Genser, Krzysztof; Yarba, Julia; Carminati, Federico; Folger, Gunter; Konstantinov, Dmitri; Pokorski, Witold; Ribon, Alberto

2017-10-01

The Geant4, GeantV and GENIE collaborations regularly perform validation and regression tests for simulation results. DoSSiER (Database of Scientific Simulation and Experimental Results) is being developed as a central repository to store the simulation results as well as the experimental data used for validation. DoSSiER is easily accessible via a web application. In addition, a web service allows for programmatic access to the repository to extract records in JSON or XML exchange formats. In this article, we describe the functionality and the current status of various components of DoSSiER as well as the technology choices we made.

Software Aspects of the Geant4 Validation Repository

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dotti, Andrea; Wenzel, Hans; Elvira, Daniel

2016-01-01

The Geant4, GeantV and GENIE collaborations regularly perform validation and regression tests for simulation results. DoSSiER (Database of Scientic Simulation and Experimental Results) is being developed as a central repository to store the simulation results as well as the experimental data used for validation. DoSSiER is easily accessible via a web application. In addition, a web service allows for programmatic access to the repository to extract records in JSON or XML exchange formats. In this article, we describe the functionality and the current status of various components of DoSSiER as well as the technology choices we made.

Resting-state functional connectivity of the amygdala in suicide attempters with major depressive disorder.

PubMed

Kang, Seung-Gul; Na, Kyoung-Sae; Choi, Jae-Won; Kim, Jeong-Hee; Son, Young-Don; Lee, Yu Jin

2017-07-03

In this study, we investigated the difference in resting-state functional connectivity (RSFC) of the amygdala between suicide attempters and non-suicide attempters with major depressive disorder (MDD) using functional magnetic resonance imaging (fMRI). This study included 19 suicide attempters with MDD and 19 non-suicide attempters with MDD. RSFC was compared between the two groups and the regression analyses were conducted to identify the correlation between RSFC and Scale for Suicide Ideation (SSI) scores in the suicide attempt group. Statistical significance was set at p-value (uncorrected) <0.005 with k≥28 voxels. Compared with non-suicide attempters, suicide attempters showed significantly increased RSFC of the left amygdala with the right insula and left superior orbitofrontal area, and increased RSFC of the right amygdala with the left middle temporal area. The regression analysis showed a significant correlation between the SSI total score and RSFC of the right amygdala with the right parahippocampal area in the suicide attempt group. The present RSFC findings provide evidence of a functional neural basis and will help reveal the pathophysiology underlying suicidality in subjects with MDD. Copyright © 2017. Published by Elsevier Inc.

20 CFR 416.266 - Continuation of SSI status for Medicaid

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Continuation of SSI status for Medicaid 416.266 Section 416.266 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

42 CFR 407.42 - Buy-in groups available to the 50 States, the District of Columbia, and the Northern Mariana...

Code of Federal Regulations, 2010 CFR

2010-10-01

... following categories: (1) Category A: Individuals who— (i) Receive SSI or SSP or both; and (ii) Are covered... they were receiving SSI or SSP; and (ii) Are covered under the State's Medicaid plan as categorically...

20 CFR 416.266 - Continuation of SSI status for Medicaid

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Continuation of SSI status for Medicaid 416.266 Section 416.266 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

20 CFR 416.266 - Continuation of SSI status for Medicaid

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Continuation of SSI status for Medicaid 416.266 Section 416.266 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

20 CFR 416.266 - Continuation of SSI status for Medicaid

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Continuation of SSI status for Medicaid 416.266 Section 416.266 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

Effect of a preoperative decontamination protocol on surgical site infections in patients undergoing elective orthopedic surgery with hardware implantation.

PubMed

Bebko, Serge P; Green, David M; Awad, Samir S

2015-05-01

Surgical site infections (SSIs), commonly caused by methicillin-resistant Staphylococcus aureus (MRSA), are associated with significant morbidity and mortality, specifically when hardware is implanted in the patient. Previously, we have demonstrated that a preoperative decontamination protocol using chlorhexidine gluconate washcloths and intranasal antiseptic ointment is effective in eradicating MRSA in the nose and on the skin of patients. To examine the effect of a decontamination protocol on SSIs in patients undergoing elective orthopedic surgery with hardware implantation. A prospective database of patients undergoing elective orthopedic surgery with hardware implantation at the Michael E. DeBakey Veterans Affairs Medical Center in Houston, Texas, was analyzed from October 1, 2012, to December 31, 2013. Cohort groups before and after the intervention were compared. Starting in May 2013, during their preoperative visit, all of the patients watched an educational video about MRSA decontamination and were given chlorhexidine washcloths and oral rinse and nasal povidone-iodine solution to be used the night before and the morning of scheduled surgery. Thirty-day SSI rates were collected according to the definitions of the Centers for Disease Control and Prevention National Nosocomial Infections Surveillance. Data on demographics, comorbidities such as chronic obstructive pulmonary disease and coronary artery disease, tobacco use, alcohol use, and body mass index were also collected. Univariate analysis was performed between the 2 groups of patients. Multivariate analysis was used to identify independent predictors of SSI. A total of 709 patients were analyzed (344 controls and 365 patients who were decolonized). Both groups were well matched with no significant differences in age, body mass index, sex, or comorbidities. All of the patients (100%) completed the MRSA decontamination protocol. The SSI rate in the intervention group was significantly lower (1.1%; 4 of 365 patients developed an SSI) than the SSI rate in the control group (3.8%; 13 of 344 patients developed an SSI) (P = .02). Multivariate logistic regression identified MRSA decontamination as an independent predictor of not developing an SSI (adjusted odds ratio, 0.24 [95% CI, 0.08-0.77]; P = .02). Our study demonstrates that preoperative MRSA decontamination with chlorhexidine washcloths and oral rinse and intranasal povidone-iodine decreased the SSI rate by more than 50% among patients undergoing elective orthopedic surgery with hardware implantation. Universal decontamination using this low-cost protocol may be considered as an additional prevention strategy for SSIs in patients undergoing orthopedic surgery with hardware implantation and warrants further study.

The Effects of Local Warming on Surgical Site Infection

PubMed Central

Dellinger, E. Patchen; Weber, James; Swenson, Ron Edward; Kent, Christopher D.; Swanson, Paul E.; Harmon, Kurt; Perrin, Margot

2015-01-01

Abstract Background: Surgical site infections (SSI) account for a major proportion of hospital-acquired infections. They are associated with longer hospital stay, readmissions, increased costs, mortality, and morbidity. Reducing SSI is a goal of the Surgical Care Improvement Project and identifying interventions that reduce SSI effectively is of interest. In a single-blinded randomized controlled trial (RCT) we evaluated the effect of localized warming applied to surgical incisions on SSI development and selected cellular (immune, endothelial) and tissue responses (oxygenation, collagen). Methods: After Institutional Review Board approval and consent, patients having open bariatric, colon, or gynecologic-oncologic related operations were enrolled and randomly assigned to local incision warming (6 post-operative treatments) or non-warming. A prototype surgical bandage was used for all patients. The study protocol included intra-operative warming to maintain core temperature ≥36°C and administration of 0.80 FIO2. Patients were followed for 6 wks for the primary outcome of SSI determined by U.S. Centers for Disease Control (CDC) criteria and ASEPSIS scores (additional treatment; presence of serous discharge, erythema, purulent exudate, and separation of the deep tissues; isolation of bacteria; and duration of inpatient stay). Tissue oxygen (PscO2) and samples for cellular analyses were obtained using subcutaneous polytetrafluoroethylene (ePTFE) tubes and oxygen micro-electrodes implanted adjacent to the incision. Cellular and tissue ePTFE samples were evaluated using flow cytometry, immunohistochemistry, and Sircol™ collagen assay (Biocolor Ltd., Carrickfergus, United Kingdom). Results: One hundred forty-six patients participated (n=73 per group). Study groups were similar on demographic parameters and for intra-operative management factors. The CDC defined rate of SSI was 18%; occurrence of SSI between groups did not differ (p=0.27). At 2 wks, warmed patients had better ASEPSIS scores (p=0.04) but this difference was not observed at 6 wks. There were no significant differences in immune, endothelial cell, or collagen responses between groups. On post-operative days one to two, warmed patients had greater PscO2 change scores with an average PscO2 increase of 9–10 mm Hg above baseline (p<0.04). Conclusions: Post-operative local warming compared with non-warming followed in this study, which included intra-operative warming to maintain normothermia and FIO2 level of 0.80, did not reduce SSI and had no effect on immune, endothelial cell presence, or collagen synthesis. PscO2 increased significantly with warming, however, the increase was modest and less than expected or what has been observed in studies testing other interventions. PMID:26125454

Relationships between starch synthase I and branching enzyme isozymes determined using double mutant rice lines

PubMed Central

2014-01-01

Background Starch is the most important carbohydrate in plant storage tissues. Multiple isozymes in at least four enzyme classes are involved in starch biosynthesis. Some of these isozymes are thought to interact and form complexes for efficient starch biosynthesis. Of these enzyme classes, starch synthases (SSs) and branching enzymes (BEs) play particularly central roles. Results We generated double mutant lines (ss1/be1 and ss1 L /be2b) between SSI (the largest component of total soluble SS activity) and BEI or BEIIb (major BEs in developing rice endosperm) to explore the relationships among these isozymes. The seed weight of ss1/be1 was comparable to that of wild type, although most ss1/be2b seeds were sterile and no double recessive plants were obtained. The seed weight of the double recessive mutant line ss1 L /be2b, derived from the leaky ss1 mutant (ss1 L ) and be2b, was higher than that of the single be2b mutant. Analyses of the chain-length distribution of amylopectin in ss1/be1 endosperm revealed additive effects of SSI and BEI on amylopectin structure. Chain-length analysis indicated that the BEIIb deficiency significantly reduced the ratio of short chains in amylopectin of ss1 L /be2b. The amylose content of endosperm starch of ss1/be1 and ss1 L /be2b was almost the same as that of wild type, whereas the endosperm starch of be2b contained more amylose than did that of wild type. SSI, BEI, and BEIIb deficiency also affected the extent of binding of other isozymes to starch granules. Conclusions Analysis of the chain-length distribution in amylopectin of the double mutant lines showed that SSI and BEI or BEIIb primarily function independently, and branching by BEIIb is followed by SSI chain elongation. The increased amylose content in be2b was because of reduced amylopectin biosynthesis; however, the lower SSI activity in this background may have enhanced amylopectin biosynthesis as a result of a correction of imbalance between the branching and elongation found in the single mutant. The fact that a deficiency of SSI, BEI, or BEIIb affected the affinity of other starch biosynthetic isozymes for the starch granule implies that there is a close interaction among SSI, BEI and BEIIb during amylopectin biosynthesis in rice endosperm. PMID:24670252

Relationships between starch synthase I and branching enzyme isozymes determined using double mutant rice lines.

PubMed

Abe, Natsuko; Asai, Hiroki; Yago, Hikari; Oitome, Naoko F; Itoh, Rumiko; Crofts, Naoko; Nakamura, Yasunori; Fujita, Naoko

2014-03-26

Starch is the most important carbohydrate in plant storage tissues. Multiple isozymes in at least four enzyme classes are involved in starch biosynthesis. Some of these isozymes are thought to interact and form complexes for efficient starch biosynthesis. Of these enzyme classes, starch synthases (SSs) and branching enzymes (BEs) play particularly central roles. We generated double mutant lines (ss1/be1 and ss1L/be2b) between SSI (the largest component of total soluble SS activity) and BEI or BEIIb (major BEs in developing rice endosperm) to explore the relationships among these isozymes. The seed weight of ss1/be1 was comparable to that of wild type, although most ss1/be2b seeds were sterile and no double recessive plants were obtained. The seed weight of the double recessive mutant line ss1L/be2b, derived from the leaky ss1 mutant (ss1L) and be2b, was higher than that of the single be2b mutant. Analyses of the chain-length distribution of amylopectin in ss1/be1 endosperm revealed additive effects of SSI and BEI on amylopectin structure. Chain-length analysis indicated that the BEIIb deficiency significantly reduced the ratio of short chains in amylopectin of ss1L/be2b. The amylose content of endosperm starch of ss1/be1 and ss1L/be2b was almost the same as that of wild type, whereas the endosperm starch of be2b contained more amylose than did that of wild type. SSI, BEI, and BEIIb deficiency also affected the extent of binding of other isozymes to starch granules. Analysis of the chain-length distribution in amylopectin of the double mutant lines showed that SSI and BEI or BEIIb primarily function independently, and branching by BEIIb is followed by SSI chain elongation. The increased amylose content in be2b was because of reduced amylopectin biosynthesis; however, the lower SSI activity in this background may have enhanced amylopectin biosynthesis as a result of a correction of imbalance between the branching and elongation found in the single mutant. The fact that a deficiency of SSI, BEI, or BEIIb affected the affinity of other starch biosynthetic isozymes for the starch granule implies that there is a close interaction among SSI, BEI and BEIIb during amylopectin biosynthesis in rice endosperm.

The role of oral antibiotics prophylaxis in prevention of surgical site infection in colorectal surgery.

PubMed

Koullouros, Michalis; Khan, Nadir; Aly, Emad H

2017-01-01

Surgical site infection (SSI) continues to be a challenge in colorectal surgery. Over the years, various modalities have been used in an attempt to reduce SSI risk in elective colorectal surgery, which include mechanical bowel preparation before surgery, oral antibiotics and intravenous antibiotic prophylaxis at induction of surgery. Even though IV antibiotics have become standard practice, there has been a debate on the exact role of oral antibiotics. The primary aim was to identify the role of oral antibiotics in reduction of SSI in elective colorectal surgery. The secondary aim was to explore any potential benefit in the use of mechanical bowel preparation (MBP) in relation to SSI in elective colorectal surgery. Medline, Embase and the Cochrane Library were searched. Any randomised controlled trials (RCTs) or cohort studies after 1980, which investigated the effectiveness of oral antibiotic prophylaxis and/or MBP in preventing SSIs in elective colorectal surgery were included. Twenty-three RCTs and eight cohorts were included. The results indicate a statistically significant advantage in preventing SSIs with the combined usage of oral and systemic antibiotic prophylaxis. Furthermore, our analysis of the cohort studies shows no benefits in the use of MBP in prevention of SSIs. The addition of oral antibiotics to systemic antibiotics could potentially reduce the risk of SSIs in elective colorectal surgery. Additionally, MBP does not seem to provide a clear benefit with regard to SSI prevention.

Randomized controlled trial of perioperative antimicrobial therapy based on the results of preoperative bile cultures in patients undergoing biliary reconstruction.

PubMed

Okamura, Kunishige; Tanaka, Kimitaka; Miura, Takumi; Nakanishi, Yoshitsugu; Noji, Takehiro; Nakamura, Toru; Tsuchikawa, Takahiro; Okamura, Keisuke; Shichinohe, Toshiaki; Hirano, Satoshi

2017-07-01

The high frequency of surgical site infections (SSIs) after hepato-pancreato-biliary (HPB) surgery is a problem that needs to be addressed. This prospective, randomized, controlled study examined whether perioperative prophylactic use of antibiotics based on preoperative bile culture results in HPB surgery could decrease SSI. Participants comprised 126 patients who underwent HPB (bile duct, gallbladder, ampullary, or pancreatic) cancer surgery with biliary reconstruction at Hokkaido University Hospital between August 2008 and March 2013 (UMIN Clinical Trial Registry #00001278). Before surgery, subjects were randomly allocated to a targeted group administered antibiotics based on bile culture results or a standard group administered cefmetazole. The primary endpoint was SSI rates within 30 days after surgery. Secondary endpoint was SSI rates for each operative procedure. Of the 126 patients, 124 were randomly allocated (targeted group, n = 62; standard group, n = 62). Frequency of SSI after surgery was significantly lower in the targeted group (27 patients, 43.5%) than in the standard group (44 patients, 71.0%; P = 0.002). Among patients who underwent pancreaticoduodenectomy and hepatectomy, SSI occurred significantly less frequently in the targeted group (P = 0.001 and P = 0.025, respectively). This study demonstrated that preoperative bile culture-targeted administration of prophylactic antibiotics decreased SSIs following HBP surgery with biliary reconstruction. © 2017 Japanese Society of Hepato-Biliary-Pancreatic Surgery.

POSTURAL CONTROL ASSESSMENT IN PHYSICALLY ACTIVE AND SEDENTARY INDIVIDUALS WITH PARAPLEGIA.

PubMed

Magnani, Paola Errera; Cliquet, Alberto; de Abreu, Daniela Cristina Carvalho

2017-01-01

The aim of this study was to evaluate functional independence and trunk control during maximum-range tasks in individuals with spinal cord injuries, who were divided into sedentary (SSI, n=10) and physically active (PASI, n=10) groups . Anamnesis was conducted and level and type of injury were identified (according to the American Spinal Injury Association protocol, ASIA) and the Functional Independence Measure (FIM) questionnaire was applied. For the forward and lateral reach task, the subjects were instructed to reach as far as possible. Mean data were compared using the unpaired t test and Mann-Whitney test and differences were considered significant when p<0.05 . The PASI group performed better in self-care activities (PASI: 40.8±0.42 points, SSI: 38.0±3.58 points, p=0.01), sphincter control (PASI: 10.5±1.84 points, SSI: 8.2±3.04 points, p=0.02), transfers (PASI: 20.7±0.48 points, SSI: 16.9±4.27 points, p=0.04), and total FIM score (PASI: 104.0±2.30 points, SSI 105.1±8.56 points, p=0.01). On the maximum reach task, the PASI group had a greater average range in all directions evaluated (p<0.05) . The continuous practice of exercise increased motor function independence and trunk control in individuals with complete spinal cord injury. Level of Evidence II, Prospective Comparative Study.

Non-observance of guidelines for surgical antimicrobial prophylaxis and surgical-site infections.

PubMed

Lallemand, S; Thouverez, M; Bailly, P; Bertrand, X; Talon, D

2002-06-01

A prospective multicentre study was conducted to assess major aspects of surgical prophylaxis and to determine whether inappropriate antimicrobial prophylaxis was a factor associated (risk or protective factor) with surgical site infection (SSI). Surgical prophylaxis practices were assessed by analysing four variables: indication, antimicrobial agent, timing and duration. Univariate and multivariate analyses were carried out to identify predictors of SSI among patient-specific, operation-specific and antimicrobial prophylaxis-specific factors. The frequency of SSI was 2.7% (13 SSI in 474 observations). Total compliance of the prescription with guidelines was observed in 41.1% of cases (195 prescriptions). Of the 139 patients who received an inappropriate drug, 126 (90.6%) received a drug with a broader spectrum than the recommended drug. Prophylaxis was prolonged in 71 (87.7%) of the 81 patients who received prophylaxis for inappropriate lengths of time and 43 (61.4%) of the 70 patients who did not receive prophylaxis at the optimal moment were treated too late. Multivariate analysis clearly demonstrated that SSI was associated with multiple procedures (relative risk 8.5), short duration of prophylaxis (relative risk 12.7) and long-term therapy with antimicrobial agents during the previous year (relative risk 8.8). The ecological risk of the emergence of resistance associated with the frequent use of broad-spectrum antibiotics and prophylaxis for longer periods was not offset by individual benefit to the patients who received inappropriate prophylaxis.

Use of Negative Pressure Wound Therapy for Lower Limb Bypass Incisions.

PubMed

Tan, Kah Wei; Lo, Zhiwen Joseph; Hong, Qiantai; Narayanan, Sriram; Tan, Glenn Wei Leong; Chandrasekar, Sadhana

2017-12-25

Objective : The use of negative pressure wound therapy (NPWT) for post-surgical cardiothoracic, orthopedic, plastic, and obstetric and gynecologic procedures has been described. However, there are no data regarding its use for lower limb bypass incisions. We aimed to investigate the outcomes of NPWT in preventing surgical site infection (SSI) in patients with lower limb arterial bypass incisions. Materials and Methods : We retrospectively used data of 42 patients who underwent lower limb arterial bypass with reversed great saphenous vein between March 2014 and June 2016 and compared conventional wound therapy and NPWT with regard to preventing SSI. Results : Twenty-eight (67%) patients underwent conventional wound therapy and 14 (33%) underwent NPWT. There were no statistical differences regarding patient characteristics and mean SSI risk scores between the two patient groups (13.7% for conventional wound therapy vs. 13.4% for NPWT; P=0.831). In the conventional group, nine instances of SSI (32%) and three (11%) of these required subsequent surgical wound debridement, whereas in the NPWT group, there was no SSI incidence (P=0.019). Secondary outcomes such as the length of hospital stay, 30-day readmission rate, and need for secondary vascular procedures were not statistically different between the two groups. Conclusion : The use of NPWT for lower limb arterial bypass incisions is superior to that of conventional wound therapy because it may prevent SSIs.

Does intraoperative low arterial partial pressure of oxygen increase the risk of surgical site infection following emergency exploratory laparotomy in horses?

PubMed

Costa-Farré, Cristina; Prades, Marta; Ribera, Thaïs; Valero, Oliver; Taurà, Pilar

2014-04-01

Decreased tissue oxygenation is a critical factor in the development of wound infection as neutrophil mediated oxidative killing is an essential mechanism against surgical pathogens. The objective of this prospective case series was to assess the impact of intraoperative arterial partial pressure of oxygen (PaO2) on surgical site infection (SSI) in horses undergoing emergency exploratory laparotomy for acute gastrointestinal disease. The anaesthetic and antibiotic protocol was standardised. Demographic data, surgical potential risk factors and PaO2, obtained 1h after induction of anaesthesia were recorded. Surgical wounds were assessed daily for infection during hospitalisation and follow up information was obtained after discharge. A total of 84 adult horses were included. SSI developed in 34 (40.4%) horses. Multivariate logistic regression showed that PaO2, anaesthetic time and subcutaneous suture material were predictors of SSI (AUC=0.76, sensitivity=71%, specificity=65%). The use of polyglycolic acid sutures increased the risk and horses with a PaO2 value < 80 mm Hg [10.6 kPa] and anaesthetic time >2h had the highest risk of developing SSI (OR=9.01; 95% CI 2.28-35.64). The results of this study confirm the hypothesis that low intraoperative PaO2 contributes to the development of SSI following colic surgery. Copyright © 2014 Elsevier Ltd. All rights reserved.

Two New Hot Spots on Io

NASA Technical Reports Server (NTRS)

1997-01-01

The Near-Infrared Mapping Spectrometer (NIMS) on Galileo obtained this image of half of Io's disk in darkness on September 19, 1997. This image, at 5 microns, shows several hot spots on Io, which are volcanic regions of enhanced thermal emission. The area shown is part of the leading hemisphere of Io.

Two new hot spots are shown and indicated in the image (New, and Shamshu). Neither of these hot spots were seen by NIMS or the Solid State Imaging Experiment, (SSI) prior to this observation, becoming only recently active. Several other previously known hot spots are labelled in the image. Galileo was at a distance of 342,000 km from Io when this observation was made.

The Jet Propulsion Laboratory, Pasadena, CA manages the mission for NASA's Office of Space Science, Washington, DC.

The Jet Propulsion Laboratory, Pasadena, CA manages the mission for NASA's Office of Space Science, Washington, DC.

This image and other images and data received from Galileo are posted on the World Wide Web, on the Galileo mission home page at URL http://galileo.jpl.nasa.gov.

20 CFR 416.351 - Deemed filing date in a case of misinformation.

Code of Federal Regulations, 2013 CFR

2013-04-01

... misinformation. 416.351 Section 416.351 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY... calls a Social Security office to inquire about filing an application for SSI benefits. During her... benefits. Ms. Jones later reads about resource exclusions under the SSI program. She recontacts the Social...

20 CFR 416.351 - Deemed filing date in a case of misinformation.

Code of Federal Regulations, 2012 CFR

2012-04-01

... misinformation. 416.351 Section 416.351 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY... calls a Social Security office to inquire about filing an application for SSI benefits. During her... benefits. Ms. Jones later reads about resource exclusions under the SSI program. She recontacts the Social...

20 CFR 416.351 - Deemed filing date in a case of misinformation.

Code of Federal Regulations, 2014 CFR

2014-04-01

... misinformation. 416.351 Section 416.351 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY... calls a Social Security office to inquire about filing an application for SSI benefits. During her... benefits. Ms. Jones later reads about resource exclusions under the SSI program. She recontacts the Social...

20 CFR 416.351 - Deemed filing date in a case of misinformation.

Code of Federal Regulations, 2011 CFR

2011-04-01

... misinformation. 416.351 Section 416.351 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY... calls a Social Security office to inquire about filing an application for SSI benefits. During her... benefits. Ms. Jones later reads about resource exclusions under the SSI program. She recontacts the Social...

National Centers for Environmental Prediction

Science.gov Websites

Modeling Center continuously monitors its NWP model performance against different performance measures, and AIRCFT GFS SSI and forecast fits to RAOBS for last 7 days spatial bias maps for different regions different regions GFS SSI and forecast fits to RAOBS for calendar months (time series, spatial and vertical

Mental Retardation: Determining Eligibility for Social Security Benefits.

ERIC Educational Resources Information Center

Reschly, Daniel J., Ed.; Myers, Tracy G., Ed.; Hartel, Christine R., Ed.

The Social Security Administration (SSA) provides income support and medical benefits for adults with mental retardation unable to perform substantial gainful activity through the Disability Insurance (DI) program and the Supplemental Security Income (SSI) program. SSI benefits are also provided to families of children and adolescents who evidence…

20 CFR 416.264 - When does the special SSI eligibility status apply.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false When does the special SSI eligibility status apply. 416.264 Section 416.264 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

20 CFR 416.351 - Deemed filing date in a case of misinformation.

Code of Federal Regulations, 2010 CFR

2010-04-01

... misinformation. 416.351 Section 416.351 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY... calls a Social Security office to inquire about filing an application for SSI benefits. During her... benefits. Ms. Jones later reads about resource exclusions under the SSI program. She recontacts the Social...

49 CFR 15.19 - Destruction of SSI.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Transportation Office of the Secretary of Transportation PROTECTION OF SENSITIVE SECURITY INFORMATION § 15.19... reconstruction of the information when the covered person no longer needs the SSI to carry out transportation security measures. (2) Exception. Paragraph (b)(1) of this section does not require a State or local...

20 CFR 416.1157 - Support and maintenance assistance.

Code of Federal Regulations, 2014 CFR

2014-04-01

... which an SSI claimant lives or an SSI claimant's ineligible spouse, parent, sponsor (or the sponsor's spouse) of an alien, or essential person. Private nonprofit agency means a religious, charitable... spouse) if you are an alien, or an essential person. We also do not consider certain support and...

A Socioscientific Curriculum Facilitating the Development of Distal and Proximal NOS Conceptualizations

ERIC Educational Resources Information Center

Schalk, Kelly A.

2012-01-01

This study reports the effects of an innovative introductory microbiology course for undergraduates that used a socioscientific issues (SSI)-based curriculum. The study illustrates how an SSI-based intervention provides learners with pragmatic opportunities for cultivating their scientific literacy subsuming the nature of science (NOS). Empirical…

20 CFR 416.1110 - What is earned income.

Code of Federal Regulations, 2010 CFR

2010-04-01

....1110 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED... else's employee. Wages are the same for SSI purposes as for the earnings test in the social security... under the SSI program are the same net earnings that we would count under the social security retirement...

49 CFR 15.19 - Destruction of SSI.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Transportation Office of the Secretary of Transportation PROTECTION OF SENSITIVE SECURITY INFORMATION § 15.19... reconstruction of the information when the covered person no longer needs the SSI to carry out transportation security measures. (2) Exception. Paragraph (b)(1) of this section does not require a State or local...

20 CFR 416.204 - Redeterminations of SSI eligibility.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Redeterminations of SSI eligibility. 416.204 Section 416.204 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE... benefits. (2) We may also redetermine your eligibility when you tell us (or we otherwise learn) of a change...

49 CFR 1520.9 - Restrictions on the disclosure of SSI.

Code of Federal Regulations, 2010 CFR

2010-10-01

... SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY SECURITY RULES FOR ALL MODES OF TRANSPORTATION PROTECTION OF SENSITIVE SECURITY INFORMATION § 1520.9 Restrictions on the disclosure of SSI. (a) Duty to... infrastructure information under section 214 of the Homeland Security Act, any covered person who is a Federal...

20 CFR 416.265 - Requirements for the special SSI eligibility status.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Requirements for the special SSI eligibility status. 416.265 Section 416.265 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

20 CFR 416.264 - When does the special SSI eligibility status apply.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false When does the special SSI eligibility status apply. 416.264 Section 416.264 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

20 CFR 416.262 - Eligibility requirements for special SSI cash benefits.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Eligibility requirements for special SSI cash benefits. 416.262 Section 416.262 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

20 CFR 416.265 - Requirements for the special SSI eligibility status.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Requirements for the special SSI eligibility status. 416.265 Section 416.265 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

20 CFR 416.265 - Requirements for the special SSI eligibility status.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Requirements for the special SSI eligibility status. 416.265 Section 416.265 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

20 CFR 416.264 - When does the special SSI eligibility status apply.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false When does the special SSI eligibility status apply. 416.264 Section 416.264 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

20 CFR 416.262 - Eligibility requirements for special SSI cash benefits.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Eligibility requirements for special SSI cash benefits. 416.262 Section 416.262 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

20 CFR 416.262 - Eligibility requirements for special SSI cash benefits.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Eligibility requirements for special SSI cash benefits. 416.262 Section 416.262 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

20 CFR 416.264 - When does the special SSI eligibility status apply.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false When does the special SSI eligibility status apply. 416.264 Section 416.264 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

Solar Array and Auroral Charging Studies of DMSP Spacecraft

NASA Technical Reports Server (NTRS)

Matias, Kelwin

2013-01-01

The SSJ electrostatic analyzers and the SSIES plasma instruments on the DMSP spacecraft in low Earth polar orbit can be used to conduct case studies of auroral and solar array charging. We will use a program written in the Interactive Data Language (IDL) to evaluate questionable charging events in the SSJ records by comparing charging signatures in SSJ and SSIES data. In addition, we will assemble a number of case studies of solar array charging showing the signatures from the SSJ data and compare to the SSIES charging signatures. In addition we will use Satellite Tool Kit (STK) to propagate orbits, obtain solar intensity, and use to verify onset of charging with sunrise.

Intraoperative interventions for preventing surgical site infection: an overview of Cochrane Reviews.

PubMed

Liu, Zhenmi; Dumville, Jo C; Norman, Gill; Westby, Maggie J; Blazeby, Jane; McFarlane, Emma; Welton, Nicky J; O'Connor, Louise; Cawthorne, Julie; George, Ryan P; Crosbie, Emma J; Rithalia, Amber D; Cheng, Hung-Yuan

2018-02-06

Surgical site infection (SSI) rates vary from 1% to 5% in the month following surgery. Due to the large number of surgical procedures conducted annually, the costs of these SSIs can be considerable in financial and social terms. Many interventions are used with the aim of reducing the risk of SSI in people undergoing surgery. These interventions can be broadly delivered at three stages: preoperatively, intraoperatively and postoperatively. The intraoperative interventions are largely focused on decontamination of skin using soap and antiseptics; the use of barriers to prevent movement of micro-organisms into incisions; and optimising the patient's own bodily functions to promote best recovery. Both decontamination and barrier methods can be aimed at people undergoing surgery and operating staff. Other interventions focused on SSI prevention may be aimed at the surgical environment and include methods of theatre cleansing and approaches to managing theatre traffic. To present an overview of Cochrane Reviews of the effectiveness and safety of interventions, delivered during the intraoperative period, aimed at preventing SSIs in all populations undergoing surgery in an operating theatre. Published Cochrane systematic reviews reporting the effectiveness of interventions delivered during the intraoperative period in terms of SSI prevention were eligible for inclusion in this overview. We also identified Cochrane protocols and title registrations for future inclusion into the overview. We searched the Cochrane Library on 01 July 2017. Two review authors independently screened search results and undertook data extraction and 'Risk of bias' and certainty assessment. We used the ROBIS (risk of bias in systematic reviews) tool to assess the quality of included reviews, and we used GRADE methods to assess the certainty of the evidence for each outcome. We summarised the characteristics of included reviews in the text and in additional tables. We included 32 Cochrane Reviews in this overview: we judged 30 reviews as being at low risk of bias and two at unclear risk of bias. Thirteen reviews had not been updated in the past three years. Two reviews had no relevant data to extract. We extracted data from 30 reviews with 349 included trials, totaling 73,053 participants. Interventions assessed included gloving, use of disposable face masks, patient oxygenation protocols, use of skin antiseptics for hand washing and patient skin preparation, vaginal preparation, microbial sealants, methods of surgical incision, antibiotic prophylaxis and methods of skin closure. Overall, the GRADE certainty of evidence for outcomes was low or very low. Of the 77 comparisons providing evidence for the outcome of SSI, seven provided high- or moderate-certainty evidence, 39 provided low-certainty evidence and 31 very low-certainty evidence. Of the nine comparisons that provided evidence for the outcome of mortality, five provided low-certainty evidence and four very low-certainty evidence.There is high- or moderate-certainty evidence for the following outcomes for these intraoperative interventions. (1) Prophylactic intravenous antibiotics administered before caesarean incision reduce SSI risk compared with administration after cord clamping (10 trials, 5041 participants; risk ratio (RR) 0.59, 95% confidence interval (CI) 0.44 to 0.81; high-certainty evidence - assessed by review authors). (2) Preoperative antibiotics reduce SSI risk compared with placebo after breast cancer surgery (6 trials, 1708 participants; RR 0.74, 95% CI 0.56 to 0.98; high-certainty evidence - assessed by overview authors). (3) Antibiotic prophylaxis probably reduce SSI risk in caesarean sections compared with no antibiotics (82 relevant trials, 14,407 participants; RR 0.40, 95% CI 0.35 to 0.46; moderate-certainty evidence; downgraded once for risk of bias - assessed by review authors). (4) Antibiotic prophylaxis probably reduces SSI risk for hernia repair compared with placebo or no treatment (17 trials, 7843 participants; RR 0.67, 95% CI 0.54 to 0.84; moderate-certainty evidence; downgraded once for risk of bias - assessed by overview authors); (5) There is currently no clear difference in the risk of SSI between iodine-impregnated adhesive drapes compared with no adhesive drapes (2 trials, 1113 participants; RR 1.03, 95% CI 0.66 to 1.60; moderate-certainty evidence; downgraded once for imprecision - assessed by review authors); (6) There is currently no clear difference in SSI risk between short-term compared with long-term duration antibiotics in colorectal surgery (7 trials; 1484 participants; RR 1.05 95% CI 0.78 to 1.40; moderate-certainty evidence; downgraded once for imprecision - assessed by overview authors). There was only one comparison showing negative effects associated with the intervention: adhesive drapes increase the risk of SSI compared with no drapes (5 trials; 3082 participants; RR 1.23, 95% CI 1.02 to 1.48; high-certainty evidence - rated by review authors). This overview provides the most up-to-date evidence on use of intraoperative treatments for the prevention of SSIs from all currently published Cochrane Reviews. There is evidence that some interventions are useful in reducing SSI risk for people undergoing surgery, such as antibiotic prophylaxis for caesarean section and hernia repair, and also the timing of prophylactic intravenous antibiotics administered before caesarean incision. Also, there is evidence that adhesive drapes increase SSI risk. Evidence for the many other treatment choices is largely of low or very low certainty and no quality-of-life or cost-effectiveness data were reported. Future trials should elucidate the relative effects of some treatments. These studies should focus on increasing participant numbers, using robust methodology and being of sufficient duration to adequately assess SSI. Assessment of other outcomes such as mortality might also be investigated as part of non-experimental prospective follow-up of people with SSI of different severity, so the risk of death for different subgroups can be better understood.

Martian airfall dust on smooth, inclined surfaces as observed on the Phoenix Mars Lander telltale mirror

NASA Astrophysics Data System (ADS)

Moores, John E.; Ha, Taesung; Lemmon, Mark T.; Gunnlaugsson, Haraldur Páll

2015-10-01

The telltale mirror, a smooth inclined surface raised over 1 m above the deck of the Phoenix Mars Lander, was observed by the Surface Stereo Imager (SSI) several times per sol during the Phoenix Mars Lander mission. These observations were combined with a radiative transfer model to determine the thickness of dust on the wind telltale mirror as a function of time. 239 telltale sequences were analyzed and dustiness was determined on a diurnal and seasonal basis. The thickness of accumulated dust did not follow any particular diurnal or seasonal trend. The dust thickness on the mirror over the mission was 0.82±0.39 μm, which suggests a similar thickness to the modal scattering particle diameter. This suggests that inclining a surface beyond the angle of repose and polishing it to remove surface imperfections is an effective way to mitigate the accumulation of dust to less than a micron over a wide range of meteorological conditions and could be beneficial for surfaces which can tolerate some dust but not thick accumulations, such as solar panels. However, such a surface will not remain completely dust free through this action alone and mechanical or electrical clearing must be employed to remove adhered dust if a pristine surface is required. The single-scattering phase function of the dust on the mirror was consistent with the single-scattering phase function of martian aerosol dust at 450 nm, suggesting that this result is inconsistent with models of the atmosphere which require vertically or horizontally separated components or broad size distributions to explain the scattering behavior of these aerosols in the blue. The single-scattering behavior of the dust on the mirror is also consistent with Hapke modeling of spherical particles. The presence of a monolayer of particles would tend to support the spherical conclusion: such particles would be most strongly adhered electrostatically.

Volcanic Activity at Tvashtar Catena, Io

NASA Technical Reports Server (NTRS)

Milazzo, M. P.; Keszthelyi, L. P.; Radebaugh, J.; Davies, A. G.; McEwen, A. S.

2004-01-01

Tvashtar Catena (63 N, 120 W) is one of the most interesting features on Io. This chain of large paterae (caldera-like depressions) has exhibited highly variable volcanic activity in a series of observations. Tvashtar is the type example of a style of volcanism seen only at high latitudes, with short-lived Pele-type plumes and short-lived by intense thermal events. Evidence for a hot spot at Tvashtar was first detected in an eclipse observation in April 1997 (orbit G7) by the Solid State Imager (SSI) on the Galileo Spacecraft. Tvashtar was originally targeted for observation at higher resolution in the close flyby in November 1999 (I25) because of its interesting large-scale topography. There are relatively few but generally larger paterae at high latitudes on Io. I25 images revealed a 25 km long, 1-2 km high lava curtain via a pattern of saturation and bleeding in the CCD image, which requires very high temperatures.

Sectoral contributions to surface water stress in the coterminous United States

NASA Astrophysics Data System (ADS)

Averyt, K.; Meldrum, J.; Caldwell, P.; Sun, G.; McNulty, S.; Huber-Lee, A.; Madden, N.

2013-09-01

Here, we assess current stress in the freshwater system based on the best available data in order to understand possible risks and vulnerabilities to regional water resources and the sectors dependent on freshwater. We present watershed-scale measures of surface water supply stress for the coterminous United States (US) using the water supply stress index (WaSSI) model which considers regional trends in both water supply and demand. A snapshot of contemporary annual water demand is compared against different water supply regimes, including current average supplies, current extreme-year supplies, and projected future average surface water flows under a changing climate. In addition, we investigate the contributions of different water demand sectors to current water stress. On average, water supplies are stressed, meaning that demands for water outstrip natural supplies in over 9% of the 2103 watersheds examined. These watersheds rely on reservoir storage, conveyance systems, and groundwater to meet current water demands. Overall, agriculture is the major demand-side driver of water stress in the US, whereas municipal stress is isolated to southern California. Water stress introduced by cooling water demands for power plants is punctuated across the US, indicating that a single power plant has the potential to stress water supplies at the watershed scale. On the supply side, watersheds in the western US are particularly sensitive to low flow events and projected long-term shifts in flow driven by climate change. The WaSSI results imply that not only are water resources in the southwest in particular at risk, but that there are also potential vulnerabilities to specific sectors, even in the ‘water-rich’ southeast.

An Assessment of the SST Simulation Using the Climate Forecast System Coupled to the SSiB Surface Model

NASA Astrophysics Data System (ADS)

Wang, Y.; Xue, Y.; Huang, B.; Lee, J.; De Sales, F.

2016-12-01

A long term simulation has been conducted using the Climate Forecast System (CFSv2) coupled to the SSiB-2 land model, which consists of the Global Forecast System atmospheric model (GFS) and the Modular Ocean model - version 4 (MOM4) as the ocean component. This study evaluates the model's performance in simulating sea surface temperature (SST) mean state, trend, and inter-annual and decadal variabilities. The model is able to produce the reasonable spatial distribution of the SST climatology; however, it has prominent large scale biases. In the middle latitude of the Northern Hemisphere, major cold biases is close to the warm side of the large SST gradients, which may be associated with the weaker Kuroshio and Gulf Stream extensions that diffuse the SST gradient. IN addition, warm biases extend along the west coast of the North America continent to the high latitude, which may be related with excessive Ekman down-welling and solar radiation fluxes reaching to the surface due to the lack of cloud there. Warm biases also exist over the tropical cold tough areas in the Pacific and Atlantic. The global SST trend and interannual variations are well captured except for that in the south Hemisphere after year 2000, which is mainly contributed by the bias from the southern Pacific Ocean. Although the model fails to accurately produce ENSO events in proper years, it does reproduce the ENSO frequency well; they are skewed toward more warm events after 1990. The model also shows ability in SST decadal variation, such as the so-called inter-decadal Pacific oscillation (IPO); however, its phases seem to go reversely compared with the observation.

Modeling biophysical/biogeochemical/ecological/ocean/atmosphere two-way interactions using NCEP CFS/SSiB5/TRIFFID/DAYCENT: challenge and promising

NASA Astrophysics Data System (ADS)

Xue, Y.; Liu, Y.; Cox, P. M.; De Sales, F.; Lee, J.; Marx, L.; Hartman, M. D.; Yang, R.; Parton, W. J.; Qiu, B.; Ek, M. B.

2016-12-01

Evaluations of several dynamic vegetation models' (DVM) performances in the offline experiments and in the CMIP5 simulations suggest that most of the DVMs substantially overestimate leaf area index (LAI) and length of the growing season, which contribute to overestimation in their coupled models' precipitation. These results suggest important deficiencies in today's DVMs but also show the importance of proper ecological processes in the Earth System Modeling. We have developed a water-carbon-energy balance-based ecosystem model (SSiB4/TRIFFID) and verified it with field and satellite measurement at seasonal to decadal and longer scales. In the global offline tests, the model was integrated from 1950 to 2010 driven by observed meteorological forcing. The simulated trend and decadal variabilities in surface ecosystem conditions (e.g., Plant functional types, LAI, GPP), and surface water and energy balances are analyzed; further experiments and analyses are carried to isolate the contribution due to elevated atmospheric carbon concentration, global warming, soil moisture, and climate variability. How nitrogen processes simulated by the DayCent model Climate Forecast System (CFS) model, which has consistently shown improvements in simulated atmospheric & ocean conditions compared with those runs with specified vegetation conditions. In an experiment, two parametrizations that calculate the mean water potential in soil layers, which affect transpiration and plants' mortality, are tested. It shows that these two methods have substantial impact on global decadal variability of precipitation and surface temperature, with even opposite signs over some regions in the worlds. These results show the uncertainty in DVM modeling with significant implication for the future prediction. It is imperative to evaluate DVMs with comprehensive observational data.

Using Our Heads and HARTSS*: Developing Perspective-Taking Skills for Socioscientific Reasoning (*Humanities, ARTS, and Social Sciences)

ERIC Educational Resources Information Center

Kahn, Sami; Zeidler, Dana L.

2016-01-01

Functional scientific literacy demands an informed citizenry capable of negotiating controversial socioscientific issues (SSI). Perspective taking is critical to SSI implementation as it enables understanding of the diverse cognitive and emotional perspectives of others. Science teacher educators must therefore facilitate teachers' promotion of…

A Framework for Socio-Scientific Issues Based Education

ERIC Educational Resources Information Center

Presley, Morgan L.; Sickel, Aaron J.; Muslu, Nilay; Merle-Johnson, Dominike; Witzig, Stephen B.; Izci, Kemal; Sadler, Troy D.

2013-01-01

Science instruction based on student exploration of socio-scientific issues (SSI) has been presented as a powerful strategy for supporting science learning and the development of scientific literacy. This paper presents an instructional framework for SSI based education. The framework is based on a series of research studies conducted in a diverse…

Lack of Evolution Acceptance Inhibits Students' Negotiation of Biology-Based Socioscientific Issues

ERIC Educational Resources Information Center

Fowler, S. R.; Zeidler, D. L.

2016-01-01

The purpose of this study was to explore science content used during college students' negotiation of biology-based socioscientific issues (SSI) and examine how it related to students' conceptual understanding and acceptance of biological evolution. The Socioscientific Issues Questionnaire (SSI-Q) was developed to measure depth of evolutionary…

Students' Environmental NOS Views, Compassion, Intent, and Action: Impact of Place-Based Socioscientific Issues Instruction

ERIC Educational Resources Information Center

Herman, Benjamin C.

2018-01-01

Preparing students to achieve the lofty goal of functional scientific literacy entails addressing the normative and non-normative facets of socioscientific issues (SSI) such as scientific processes, the nature of science (NOS) and diverse sociocultural perspectives. SSI instructional approaches have demonstrated some efficacy for promoting…

77 FR 57178 - Agency Information Collection Activities: Proposed Request

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-17

...) maintain a written record of the request; (2) establish the relationship of the requester to the deceased... Maintain Home-- 20 CFR 416.212(b)(1)--0960-0516. When SSI recipients (1) enter a public institution or (2... from the recipient, the recipient's family, or friends confirming SSI payments are needed to maintain...

A Comparison between SRSS-IE and SSiS-PSG Scores: Examining Convergent Validity

ERIC Educational Resources Information Center

Lane, Kathleen Lynne; Oakes, Wendy Peia; Common, Eric Alan; Zorigian, Kris; Brunsting, Nelson C.; Schatschneider, Christopher

2015-01-01

We report findings of a validation study comparing two screening tools: the Student Risk Screening Scale-Internalizing and Externalizing (SRSS-IE, an adapted version of the Student Risk Screening Scale) and the Social Skills Improvement System-Performance Screening Guide (SSiS-PSG). Participants included 458 kindergarten through fifth-grade…

Additional Evidence of Convergent Validity between SRSS-IE and SSiS-PSG Scores

ERIC Educational Resources Information Center

Lane, Kathleen Lynne; Oakes, Wendy Peia; Ennis, Robin Parks; Royer, David James

2015-01-01

We report findings of a validity study comparing two screening tools: the Student Risk Screening Scale-Internalizing and Externalizing (SRSS-IE) and the Social Skills Improvement System-Performance Screening Guide (SSiS-PSG; Elliott & Gresham, 2007). Participants were 1,680 kindergarten through sixth-grade elementary students from three…

Promoting the Role of the Personal Narrative in Teaching Controversial Socio-Scientific Issues

ERIC Educational Resources Information Center

Levinson, Ralph

2008-01-01

Citizens participating in contemporary socio-scientific issues (SSI) need to draw on local knowledge and personal experience. If curricular developments in the teaching of controversial SSI are to reflect contemporary notions of citizenship then the personal narrative is an indispensable instrument in bridging the gap between the local/personal…

20 CFR 416.261 - What are special SSI cash benefits and when are they payable.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false What are special SSI cash benefits and when are they payable. 416.261 Section 416.261 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who...

49 CFR 15.9 - Restrictions on the disclosure of SSI.

Code of Federal Regulations, 2011 CFR

2011-10-01

... information under section 214 of the Homeland Security Act, any covered person who is a Federal employee in... Section 15.9 Transportation Office of the Secretary of Transportation PROTECTION OF SENSITIVE SECURITY INFORMATION § 15.9 Restrictions on the disclosure of SSI. (a) Duty to protect information. A covered person...

49 CFR 1520.9 - Restrictions on the disclosure of SSI.

Code of Federal Regulations, 2011 CFR

2011-10-01

... inform TSA or the applicable DOT or DHS component or agency. (d) Additional Requirements for Critical Infrastructure Information. In the case of information that is both SSI and has been designated as critical infrastructure information under section 214 of the Homeland Security Act, any covered person who is a Federal...

49 CFR 1520.9 - Restrictions on the disclosure of SSI.

Code of Federal Regulations, 2013 CFR

2013-10-01

... inform TSA or the applicable DOT or DHS component or agency. (d) Additional Requirements for Critical Infrastructure Information. In the case of information that is both SSI and has been designated as critical infrastructure information under section 214 of the Homeland Security Act, any covered person who is a Federal...

49 CFR 1520.9 - Restrictions on the disclosure of SSI.

Code of Federal Regulations, 2014 CFR

2014-10-01

... inform TSA or the applicable DOT or DHS component or agency. (d) Additional Requirements for Critical Infrastructure Information. In the case of information that is both SSI and has been designated as critical infrastructure information under section 214 of the Homeland Security Act, any covered person who is a Federal...

49 CFR 1520.9 - Restrictions on the disclosure of SSI.

Code of Federal Regulations, 2012 CFR

2012-10-01

... inform TSA or the applicable DOT or DHS component or agency. (d) Additional Requirements for Critical Infrastructure Information. In the case of information that is both SSI and has been designated as critical infrastructure information under section 214 of the Homeland Security Act, any covered person who is a Federal...

Secondary School Students' Understanding of Science and Their Socioscientific Reasoning

ERIC Educational Resources Information Center

Karahan, Engin; Roehrig, Gillian

2017-01-01

Research in socioscientific issue (SSI)-based interventions is relatively new (Sadler in "Journal of Research in Science Teaching" 41:513-536, 2004; Zeidler et al. in "Journal of Research in Science Teaching" 46:74-101, 2009), and there is a need for understanding more about the effects of SSI-based learning environments…

20 CFR 416.250 - Experimental, pilot, and demonstration projects in the SSI program.

Code of Federal Regulations, 2011 CFR

2011-04-01

... you are placed in a control group which is not subject to the alternative requirements, limitations... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Experimental, pilot, and demonstration... Because of Essential Persons § 416.250 Experimental, pilot, and demonstration projects in the SSI program...

20 CFR 416.250 - Experimental, pilot, and demonstration projects in the SSI program.

Code of Federal Regulations, 2013 CFR

2013-04-01

... you are placed in a control group which is not subject to the alternative requirements, limitations... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Experimental, pilot, and demonstration... Because of Essential Persons § 416.250 Experimental, pilot, and demonstration projects in the SSI program...

20 CFR 416.250 - Experimental, pilot, and demonstration projects in the SSI program.

Code of Federal Regulations, 2014 CFR

2014-04-01

... you are placed in a control group which is not subject to the alternative requirements, limitations... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Experimental, pilot, and demonstration... Because of Essential Persons § 416.250 Experimental, pilot, and demonstration projects in the SSI program...

20 CFR 416.250 - Experimental, pilot, and demonstration projects in the SSI program.

Code of Federal Regulations, 2012 CFR

2012-04-01

... you are placed in a control group which is not subject to the alternative requirements, limitations... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Experimental, pilot, and demonstration... Because of Essential Persons § 416.250 Experimental, pilot, and demonstration projects in the SSI program...

20 CFR 416.250 - Experimental, pilot, and demonstration projects in the SSI program.

Code of Federal Regulations, 2010 CFR

2010-04-01

... you are placed in a control group which is not subject to the alternative requirements, limitations... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Experimental, pilot, and demonstration... Because of Essential Persons § 416.250 Experimental, pilot, and demonstration projects in the SSI program...

49 CFR 15.9 - Restrictions on the disclosure of SSI.

Code of Federal Regulations, 2010 CFR

2010-10-01

... information under section 214 of the Homeland Security Act, any covered person who is a Federal employee in... Section 15.9 Transportation Office of the Secretary of Transportation PROTECTION OF SENSITIVE SECURITY INFORMATION § 15.9 Restrictions on the disclosure of SSI. (a) Duty to protect information. A covered person...

Earth-based and Galileo SSI multispectral observations of eastern mare serenitatis and the Apollo 17 landing site

NASA Technical Reports Server (NTRS)

Hiesinger, H.; Jaumann, R.; Neukum, G.

1993-01-01

Both the Apollo 17 and the Mare Serenitatis region were observed by Galileo during its fly-by in December 1992. We used earth-based multispectral data to define mare units which then can be compared with the results of the Galileo SSI data evaluation.

49 CFR 1520.15 - SSI disclosed by TSA or the Coast Guard.

Code of Federal Regulations, 2010 CFR

2010-10-01

... SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY SECURITY RULES FOR ALL MODES OF TRANSPORTATION PROTECTION OF SENSITIVE SECURITY INFORMATION § 1520.15 SSI disclosed by TSA or the Coast Guard. (a) In... allegations contained in a legal enforcement action document issued by TSA or the Coast Guard. (2) Security...

Socioscientific Issues-Based Instruction: An Investigation of Agriscience Students' Content Knowledge Based on Student Variables

ERIC Educational Resources Information Center

Shoulders, Catherine W.; Myers, Brian E.

2013-01-01

Numerous researchers in science education have reported student improvement in areas of scientific literacy resulting from socioscientific issues (SSI)-based instruction. The purpose of this study was to describe student agriscience content knowledge following a six-week SSI-based instructional unit focusing on the introduction of cultured meat…

Teaching with Socio-Scientific Issues in Physical Science: Teacher and Students' Experiences

ERIC Educational Resources Information Center

Talens, Joy

2016-01-01

Socio-scientific issues (SSI) are recommended by many science educators worldwide for learners to acquire first hand experience to apply what they learned in class. This investigated experiences of teacher-researcher and students in using SSI in Physical Science, Second Semester, School Year 2012-2013. Latest and controversial news articles on…

Exploring Preservice Elementary Teachers' Critique and Adaptation of Science Curriculum Materials in Respect to Socioscientific Issues

ERIC Educational Resources Information Center

Forbes, Cory T.; Davis, Elizabeth A.

2008-01-01

The work presented here represents a preliminary effort undertaken to address the role of teachers in supporting students' learning and decision-making about socioscientific issues (SSI) by characterizing preservice elementary teachers' critique and adaptation of SSI-based science curriculum materials and identifying factors that serve to mediate…

20 CFR 416.265 - Requirements for the special SSI eligibility status.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Requirements for the special SSI eligibility status. 416.265 Section 416.265 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A Disabling Impairment § 416.265 Requirement...

20 CFR 416.262 - Eligibility requirements for special SSI cash benefits.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Eligibility requirements for special SSI cash benefits. 416.262 Section 416.262 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A Disabling Impairment § 416.262...

76 FR 446 - Supplemental Security Income (SSI) for the Aged, Blind, and Disabled; Dedicated Accounts and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-05

... SOCIAL SECURITY ADMINISTRATION 20 CFR Part 416 [Docket No. SSA-2008-0050] RIN 0960-AE59... Payments for Certain Past- Due SSI Benefits AGENCY: Social Security Administration (SSA). ACTION: Final rules. SUMMARY: These final rules adopt, with some minor changes, the interim final rules with request...

75 FR 1271 - Technical Revisions to the Supplemental Security Income (SSI) Regulations on Income and Resources

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-11

... SOCIAL SECURITY ADMINISTRATION 20 CFR Part 416 [Docket No. SSA 2008-0034] RIN 0960-AG66 Technical Revisions to the Supplemental Security Income (SSI) Regulations on Income and Resources AGENCY: Social... revisions reflect legislative changes found in the Consolidated Appropriations Act of 2001 (CAA), the...

20 CFR 416.261 - What are special SSI cash benefits and when are they payable.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false What are special SSI cash benefits and when are they payable. 416.261 Section 416.261 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who...

20 CFR 416.261 - What are special SSI cash benefits and when are they payable.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false What are special SSI cash benefits and when are they payable. 416.261 Section 416.261 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who...

20 CFR 416.261 - What are special SSI cash benefits and when are they payable.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false What are special SSI cash benefits and when are they payable. 416.261 Section 416.261 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who...

Influence of Shiftwork on Greek Nursing Personnel

PubMed Central

Korompeli, Anna; Muurlink, Olav; Tzavara, Chara; Velonakis, Emmanouel; Lemonidou, Chrysoula; Sourtzi, Panayota

2014-01-01

Background The aim of this study was to investigate the burden experienced by nursing personnel working irregular shifts in Greece and to conduct the first test of a Greek version of the Standard Shiftwork Index (SSI). Methods A cross-sectional survey was carried out. The SSI was completed by 365 nurses and nursing assistants working shifts, including nights. Results Female nursing personnel and those suffering from a chronic disease were most affected by working rotating shifts as they had elevated scores on the majority of the SSI scales, such as sleep, chronic fatigue, digestive and cardiovascular problems, general health questionnaire, cognitive and somatic anxiety, shift time satisfaction, engagement and disengagement strategies, languidity, flexibility, and neurotisicm. Nurses with longer working experience and those with family responsibilities also scored higher on some of the SSI scales, such as the sleep, shift time satisfaction, social and domestic disruption, disengagement strategies, morningness, and languidity scales. Conclusion Shiftwork affects female nurses, those with chronic disease, older age, and domestic responsibilities more severely. Therefore management should take these factors into account when designing work schedules to alleviate the burden caused by shiftwork. PMID:25180137

Prophylactic antibiotics used in patients of hepatobiliary surgery.

PubMed

Ren, Jianjun; Bao, Lidao; Niu, Jianxiang; Wang, Yi; Ren, Xianhua

2013-09-01

To clarify the use of antibiotics in our hospital and to guide the prophylactic use in future hepatobiliary surgical procedures. A retrospective review of patients who underwent hepatobiliary surgery from January 2011 to June 2011 was included. Data were collected, and surgical site infection (SSI) was defined by the criteria of Center for Disease Control and Prevention. Patients were prescribed antibiotics for the clinical diagnosis of hepatobiliary system diseases. 1564 patients were identified, in which 784 patients (50.13%) did not receive preoperative antibiotic prophylaxis. Of these 355 patients with 784 surgical sites received either preoperative or both preoperative and postoperative antibiotic prophylaxis. The SSI rate of the patients who received prophylaxis alone (2.56%, 20 of 780 sites) was not statistically higher than that of the patients who have not received prophylaxis (2.68%, 21 of 784 sites), and the two groups were not statistically correlated (P=0.77). The number of the patients who developed SSI was relatively low, and no reduction in the SSI rate was observed among the patients who have received antibiotic prophylaxis.

Evaluation of anesthetic technique on surgical site infections (SSIs) at a single institution.

PubMed

Curry, Craig S; Smith, Kahsi A; Allyn, John W

2014-12-01

To determine whether the previously published relationship between anesthetic technique and rate of surgical site infections (SSIs) was influenced by institution specific effects. Retrospective Review of Quality Assurance and Hospital Epidemiology databases. Metropolitan medical center. The records of 7,751 patients who underwent knee or hip joint replacement from 2004 to 2010 were analyzed. Data regarding anesthetic technique, age, ASA status, gender, postoperative temperature, duration of anesthesia and type of surgery were from the department of anesthesiology quality assurance database and SSI cases were identified from the department of epidemiology database. The impact of anesthetic technique and other variables was assessed using bivariate and multivariate techniques. There was no association of anesthetic technique on the rate of SSI. Duration of anesthesia and ASA status were associated with effects on the rate of SSI. The impact of anesthetic technique on SSI following hip and knee replacement surgery may be site specific and using locally gathered quality data may assist in assessing specific institutional impact. Copyright © 2014 Elsevier Inc. All rights reserved.

SSI recipients in domiciliary care facilities: federally administered optional supplementation, March 1976.

PubMed

Kochhar, S

1977-12-01

Under the supplemental security income program, federally administered payments amounting to $24.7 million were made in March 1976 to 107,000 persons who were residing in domiciliary care facilities and under other supervised living arrangements. These persons were unable to function under totally independent living arrangements but did not require medical or nursing care on a regular basis. Of the total, $9.5 million was represented in Federal SSI payments and $15.2 million came from optional State supplements--with California paying $6.2 million and New York $4.6 million. The average payment to the residents of these facilities was $232 a month. Comparable data for four States show greater caseload growth for persons in domiciliary care facilities and under other supervised living arrangements than for the total SSI population. Nearly two-thirds of the States are adding funds to Federal SSI payments for persons under such care. Data are available, however, only from Social Security Administration program records for those States that have elected Federal administration of their optional programs.

Modification of Soil Temperature and Moisture Budgets by Snow Processes

NASA Astrophysics Data System (ADS)

Feng, X.; Houser, P.

2006-12-01

Snow cover significantly influences the land surface energy and surface moisture budgets. Snow thermally insulates the soil column from large and rapid temperature fluctuations, and snow melting provides an important source for surface runoff and soil moisture. Therefore, it is important to accurately understand and predict the energy and moisture exchange between surface and subsurface associated with snow accumulation and ablation. The objective of this study is to understand the impact of land surface model soil layering treatment on the realistic simulation of soil temperature and soil moisture. We seek to understand how many soil layers are required to fully take into account soil thermodynamic properties and hydrological process while also honoring efficient calculation and inexpensive computation? This work attempts to address this question using field measurements from the Cold Land Processes Field Experiment (CLPX). In addition, to gain a better understanding of surface heat and surface moisture transfer process between land surface and deep soil involved in snow processes, numerical simulations were performed at several Meso-Cell Study Areas (MSAs) of CLPX using the Center for Ocean-Land-Atmosphere (COLA) Simplified Version of the Simple Biosphere Model (SSiB). Measurements of soil temperature and soil moisture were analyzed at several CLPX sites with different vegetation and soil features. The monthly mean vertical profile of soil temperature during October 2002 to July 2003 at North Park Illinois River exhibits a large near surface variation (<5 cm), reveals a significant transition zone from 5 cm to 25 cm, and becomes uniform beyond 25cm. This result shows us that three soil layers are reasonable in solving the vertical variation of soil temperature at these study sites. With 6 soil layers, SSiB also captures the vertical variation of soil temperature during entire winter season, featuring with six soil layers, but the bare soil temperature is underestimated and root-zone soil temperature is overestimated during snow melting; which leads to overestimated temperature variations down to 20 cm. This is caused by extra heat loss from upper soil level and insufficient heat transport from the deep soil. Further work will need to verify if soil temperature displays similar vertical thermal structure for different vegetation and soil types during snow season. This study provides insight to the surface and subsurface thermodynamic and hydrological processes involved in snow modeling which is important for accurate snow simulation.

Geologic map of Io

USGS Publications Warehouse

Williams, David A.; Keszthelyi, Laszlo P.; Crown, David A.; Yff, Jessica A.; Jaeger, Windy L.; Schenk, Paul M.; Geissler, Paul E.; Becker, Tammy L.

2011-01-01

Io, discovered by Galileo Galilei on January 7–13, 1610, is the innermost of the four Galilean satellites of the planet Jupiter (Galilei, 1610). It is the most volcanically active object in the Solar System, as recognized by observations from six National Aeronautics and Space Administration (NASA) spacecraft: Voyager 1 (March 1979), Voyager 2 (July 1979), Hubble Space Telescope (1990–present), Galileo (1996–2001), Cassini (December 2000), and New Horizons (February 2007). The lack of impact craters on Io in any spacecraft images at any resolution attests to the high resurfacing rate (1 cm/yr) and the dominant role of active volcanism in shaping its surface. High-temperature hot spots detected by the Galileo Solid-State Imager (SSI), Near-Infrared Mapping Spectrometer (NIMS), and Photopolarimeter-Radiometer (PPR) usually correlate with darkest materials on the surface, suggesting active volcanism. The Voyager flybys obtained complete coverage of Io's subjovian hemisphere at 500 m/pixel to 2 km/pixel, and most of the rest of the satellite at 5–20 km/pixel. Repeated Galileo flybys obtained complementary coverage of Io's antijovian hemisphere at 5 m/pixel to 1.4 km/pixel. Thus, the Voyager and Galileo data sets were merged to enable the characterization of the whole surface of the satellite at a consistent resolution. The United States Geological Survey (USGS) produced a set of four global mosaics of Io in visible wavelengths at a spatial resolution of 1 km/pixel, released in February 2006, which we have used as base maps for this new global geologic map. Much has been learned about Io's volcanism, tectonics, degradation, and interior since the Voyager flybys, primarily during and following the Galileo Mission at Jupiter (December 1995–September 2003), and the results have been summarized in books published after the end of the Galileo Mission. Our mapping incorporates this new understanding to assist in map unit definition and to provide a global synthesis of Io's geology.

Students' Experience of Working with Socioscientific Issues - a Quantitative Study in Secondary School

NASA Astrophysics Data System (ADS)

Ottander, Christina; Ekborg, Margareta

2012-12-01

This research project aims to investigate how students in lower secondary school experience work with socioscientific issues (SSI). The six socioscientific cases developed and used in this project are relevant according to characteristics of SSI and to the national curriculum. Approximately 1,500 students in Sweden have worked with one SSI case chosen by the teachers. A questionnaire-based instrument was used to measure the affective domain of students' attitudes towards and interest in science before starting to work with the case and a second questionnaire after finishing a case. The second student questionnaire, measured the situational characteristics of the SSI work and perceived cognitive and affective outcomes. According to the students' self-reported experience, all cases were interesting and related to a current issue. Most cases were equally interesting to boys and girls, the only exception was You are what you eat, which girls found more interesting than boys did. Almost all students claim that they learnt new facts, learnt to argue for their standpoint and to search and evaluate information during the work with the cases. The girls' average scores were higher on several aspects of learning outcomes. Furthermore the students, especially the girls, perceived that the outcome of working with SSI had relevance for their future, with some cases more relevant than others. The more interesting the student found the case, the more they claimed they learnt. The students do not, however, claim that they learnt more science than during ordinary lessons.

Collaboration with an infection control team for patients with infection after spine surgery.

PubMed

Kobayashi, Kazuyoshi; Imagama, Shiro; Kato, Daizo; Ando, Kei; Hida, Tetsuro; Ito, Kenyu; Tsushima, Mikito; Matsumoto, Akiyuki; Morozumi, Masayoshi; Tanaka, Satoshi; Yagi, Tetsuya; Nishida, Yoshihiro; Ishiguro, Naoki

2017-07-01

The risk of infection, including surgical site infection (SSI), after spine surgery has increased due to aging and more immunocompromised hosts. An infection control team (ICT) is responsible for management of health care-associated infections at our institution. The study subjects were 40 patients (18 men and 22 women with an average age of 54 years) referred to the ICT after spine surgery since 2010. Pathogenic bacteria and treatment in these cases were reviewed. Collaboration with the ICT involved guidance on use of antibiotics for infection in 30 patients (16 SSI and 14 non-SSI) and a search for the infection focus for fever of unknown origin in 10 patients (7 patients were found to have urinary tract infections and 2 patients were found to have pneumonia). The detection rate of causative bacteria in ICT consultation was 88% (35 out of 40 patients). SSI patients with instrumentation involved had a significantly higher rate of methicillin-resistant Staphylococcus aureus infection compared with those without instrumentation (42% vs 13%; P < .05). All cases of SSI with instrumentation involved were cured by ICT support without removal of instrumentation. Early assistance from the ICT was important for prevention of worsening of methicillin-resistant S aureus infection. Collaboration with the ICT was helpful for detection of pathogenic bacteria and allowed appropriate use of antibiotics at an early stage. Copyright © 2017 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

POSTURAL CONTROL ASSESSMENT IN PHYSICALLY ACTIVE AND SEDENTARY INDIVIDUALS WITH PARAPLEGIA

PubMed Central

Magnani, Paola Errera; Cliquet, Alberto; de Abreu, Daniela Cristina Carvalho

2017-01-01

ABSTRACT Objective: The aim of this study was to evaluate functional independence and trunk control during maximum-range tasks in individuals with spinal cord injuries, who were divided into sedentary (SSI, n=10) and physically active (PASI, n=10) groups . Methods: Anamnesis was conducted and level and type of injury were identified (according to the American Spinal Injury Association protocol, ASIA) and the Functional Independence Measure (FIM) questionnaire was applied. For the forward and lateral reach task, the subjects were instructed to reach as far as possible. Mean data were compared using the unpaired t test and Mann-Whitney test and differences were considered significant when p<0.05 . Results: The PASI group performed better in self-care activities (PASI: 40.8±0.42 points, SSI: 38.0±3.58 points, p=0.01), sphincter control (PASI: 10.5±1.84 points, SSI: 8.2±3.04 points, p=0.02), transfers (PASI: 20.7±0.48 points, SSI: 16.9±4.27 points, p=0.04), and total FIM score (PASI: 104.0±2.30 points, SSI 105.1±8.56 points, p=0.01). On the maximum reach task, the PASI group had a greater average range in all directions evaluated (p<0.05) . Conclusion: The continuous practice of exercise increased motor function independence and trunk control in individuals with complete spinal cord injury. Level of Evidence II, Prospective Comparative Study. PMID:28955171