Sample records for swanson analysis systems

  1. Systems Approaches to the Management of Public Education.

    ERIC Educational Resources Information Center

    Mansergh, Gerald G., Ed.

    Three major presentations made at an October 1968 conference at Hartland, Michigan, for public school administrators and university professors are "The Systems Movement and Educational Administration," by Glenn L. Immegart; "Cost-Utility Analysis and Educational Decision-Making," by Austin D. Swanson; and "Educational…

  2. Swanson exercises on the CEVIS in the US Lab

    NASA Image and Video Library

    2014-04-22

    ISS039-E-014696 (22 April 2014) --- Expedition 39 Flight Engineer Steve Swanson of NASA, works out on the Cycle Ergometer with Vibration Isolation System (CEVIS) in the U.S. lab Destiny of the International Space Station.

  3. Swanson uses communication equipment in the A/L during Joint Operations

    NASA Image and Video Library

    2007-06-12

    S117-E-07099 (12 June 2007) --- Astronaut Steven Swanson, STS-117 mission specialist, uses a communication system in the Quest Airlock of the International Space Station during flight day five activities while Space Shuttle Atlantis was docked with the station.

  4. Swanson conducts CFE session

    NASA Image and Video Library

    2014-07-03

    ISS040-E-032827 (3 July 2014) --- NASA astronaut Steve Swanson, Expedition 40 commander, conducts a session with the Capillary Flow Experiment (CFE) in the Harmony node of the International Space Station. CFE is a suite of fluid physics experiments that investigate how fluids move up surfaces in microgravity. The results aim to improve current computer models that are used by designers of low gravity fluid systems and may improve fluid transfer systems for water on future spacecraft.

  5. Swanson conducts CFE session

    NASA Image and Video Library

    2014-07-03

    ISS040-E-032825 (3 July 2014) --- NASA astronaut Steve Swanson, Expedition 40 commander, conducts a session with the Capillary Flow Experiment (CFE) in the Harmony node of the International Space Station. CFE is a suite of fluid physics experiments that investigate how fluids move up surfaces in microgravity. The results aim to improve current computer models that are used by designers of low gravity fluid systems and may improve fluid transfer systems for water on future spacecraft.

  6. Swanson conducts CFE session

    NASA Image and Video Library

    2014-07-03

    ISS040-E-032820 (3 July 2014) --- NASA astronaut Steve Swanson, Expedition 40 commander, conducts a session with the Capillary Flow Experiment (CFE) in the Harmony node of the International Space Station. CFE is a suite of fluid physics experiments that investigate how fluids move up surfaces in microgravity. The results aim to improve current computer models that are used by designers of low gravity fluid systems and may improve fluid transfer systems for water on future spacecraft.

  7. Finite element meshing of ANSYS (trademark) solid models

    NASA Technical Reports Server (NTRS)

    Kelley, F. S.

    1987-01-01

    A large scale, general purpose finite element computer program, ANSYS, developed and marketed by Swanson Analysis Systems, Inc. is discussed. ANSYS was perhaps the first commercially available program to offer truly interactive finite element model generation. ANSYS's purpose is for solid modeling. This application is briefly discussed and illustrated.

  8. Swanson in U.S. Laboratory

    NASA Image and Video Library

    2014-09-02

    ISS040-E-123259 (2 Sept. 2014) --- NASA astronaut Steve Swanson, Expedition 40 commander, prepares to set up the Portable Pulmonary Function System hardware for Sprint VO2max sessions in the Destiny laboratory of the International Space Station. The Sprint experiment measures the effectiveness of high-intensity, low-volume exercise training in minimizing the loss of muscle mass and bone density that occurs during spaceflight.

  9. Swanson in U.S. Laboratory

    NASA Image and Video Library

    2014-09-02

    ISS040-E-123262 (2 Sept. 2014) --- NASA astronaut Steve Swanson, Expedition 40 commander, sets up the Portable Pulmonary Function System hardware for Sprint VO2max sessions in the Destiny laboratory of the International Space Station. The Sprint experiment measures the effectiveness of high-intensity, low-volume exercise training in minimizing the loss of muscle mass and bone density that occurs during spaceflight.

  10. Factors associated with infection following open distal radius fractures.

    PubMed

    Glueck, Dane A; Charoglu, Constantine P; Lawton, Jeffrey N

    2009-09-01

    Open fractures are often classified according to a system described by Gustilo and Anderson. However, this system was applied to open long bone fractures, which may not predict the incidence of infection in open metaphyseal fractures of the upper extremity. Other studies have found that wound contamination and systemic illness were the best predictors of infections in open hand fractures. Our study assessed infection in open distal radius fractures and identifies factors that are associated with these infections. We hypothesize that contamination, rather than absolute wound size, is the best predictor of infection associated with open distal radius fractures. A review by CPT code yielded 42 patients with open distal radius fractures between 1997 and 2002 treated at a level one trauma center. Medical records and radiographic follow-up were reviewed to assess the time to irrigation and debridement, the number of debridements in initial treatment period, the method of operative stabilization, the Gustilo and Anderson type of fracture, the Swanson type of fracture, and description of wound contamination. Forty-two patients were followed up for an average of 15 months (range 4 to 68 months). Twenty-four fractures were classified as Gustilo and Anderson type I, ten were type II, and eight were type III, 30 were Swanson type I, and 12 were Swanson type II. Five of the 42 fractures were considered contaminated. Two were exposed to fecal contamination. The others were contaminated with tar, dirt/grass, and gravel, respectively. Three of 42 (7%) fractures developed infections. All three infected cases received a single irrigation and debridement. Two of five contaminated fractures (40%) developed a polymicrobial infection. Both were exposed to fecal contamination and, therefore, considered Swanson type II fractures. They were classified as Gustilo and Anderson type II and IIIB based solely upon the size of the wound. Both required multiple debridements and eventually wrist fusions. The third infection occurred in a Gustilo and Anderson type II and Swanson type I open fracture treated with one debridement and plate fixation. Hardware removal, debridement, and antibiotics resolved the infection. Three contaminated fractures that healed uneventfully received two debridements. Statistical analysis revealed a correlation with infection and contamination (p = 0.0331). The number of initial debridements played a role in infection, but was not statistically significant. No relationship between infection and time to initial irrigation and debridement, method of fixation, Gustilo and Anderson type, or Swanson type was found. We propose that open distal radius fractures behave differently than open long bone fractures. Infection developed in 7% of the distal radius fractures in our study and was significantly associated with wound contamination. We recommend that contamination be included as factor for prognosis in open distal radius fractures. Contaminated fractures should be treated with multiple debridements as part of the initial plan not based upon subsequent development of an infection.

  11. Conceptual biology, hypothesis discovery, and text mining: Swanson's legacy.

    PubMed

    Bekhuis, Tanja

    2006-04-03

    Innovative biomedical librarians and information specialists who want to expand their roles as expert searchers need to know about profound changes in biology and parallel trends in text mining. In recent years, conceptual biology has emerged as a complement to empirical biology. This is partly in response to the availability of massive digital resources such as the network of databases for molecular biologists at the National Center for Biotechnology Information. Developments in text mining and hypothesis discovery systems based on the early work of Swanson, a mathematician and information scientist, are coincident with the emergence of conceptual biology. Very little has been written to introduce biomedical digital librarians to these new trends. In this paper, background for data and text mining, as well as for knowledge discovery in databases (KDD) and in text (KDT) is presented, then a brief review of Swanson's ideas, followed by a discussion of recent approaches to hypothesis discovery and testing. 'Testing' in the context of text mining involves partially automated methods for finding evidence in the literature to support hypothetical relationships. Concluding remarks follow regarding (a) the limits of current strategies for evaluation of hypothesis discovery systems and (b) the role of literature-based discovery in concert with empirical research. Report of an informatics-driven literature review for biomarkers of systemic lupus erythematosus is mentioned. Swanson's vision of the hidden value in the literature of science and, by extension, in biomedical digital databases, is still remarkably generative for information scientists, biologists, and physicians.

  12. Swanson during EVA Tool Configuration in the A/L

    NASA Image and Video Library

    2014-04-17

    ISS039-E-013091 (17 April 2014) --- NASA astronaut Steve Swanson, Expedition 39 flight engineer, is seen in the Quest airlock of the Earth-orbiting International Space Station. He and NASA astronaut Rick Mastracchio, flight engineer, will conduct a spacewalk in the coming week to replace a failed backup computer relay system on the space station's truss. The activity, designated U.S. EVA 26, will be broadcast live on NASA Television. A pair of NASA extravehicular mobility units (EMU) can be seen in the foreground.

  13. The Classification of Swanson for Congenital Anomalies of Upper Limb Modified by the Japanese Society for Surgery of the Hand (JSSH).

    PubMed

    Iba, Kousuke; Horii, Emiko; Ogino, Toshihiko; Kazuki, Kenichi; Kashiwa, Katsuhiko

    2015-01-01

    The aim of this study is to introduce the classification of Swanson for congenital anomalies of upper limb modified by the Japanese Society for Surgery of the Hand (the JSSH modification) in English. The Swanson classification has been widely accepted by most hand surgeons. However, several authors have suggested that complex cases, particularly those involving the complex spectrum of cleft hand and symbrachydactyly, are difficult to classify into the classification schemes. In the JSSH modification, brachysyndactyly, so-called atypical cleft hand and transverse deficiency are included under the same concept of transverse deficiency. Cleft hand, central polydactyly, and syndactyly are included in the same category of abnormal induction of digital rays. We believe that the JSSH modification system is effective in providing hand surgeons with the clinical features and conditions for congenital anomalies.

  14. Swanson prepares to retract the P6 Truss STBD SAW during EVA 2

    NASA Image and Video Library

    2007-06-13

    S117-E-07233 (13 June 2007) --- Astronauts Steven Swanson and Patrick Forrester (out of frame), both STS-117 mission specialists, participate in the mission's second planned session of extravehicular activity (EVA), as construction resumes on the International Space Station. Among other tasks, Forrester and Swanson removed all of the launch locks holding the 10-foot-wide solar alpha rotary joint in place and began the solar array retraction. Tethered to his Extravehicular Mobility Unit (EMU) spacesuit, a hockey-stick-shaped tool wrapped in insulating tape, is visible in front of Swanson.

  15. Swanson prepares to retract the P6 Truss STBD SAW during EVA 2

    NASA Image and Video Library

    2007-06-13

    S117-E-07234 (13 June 2007) --- Astronauts Steven Swanson and Patrick Forrester (out of frame), both STS-117 mission specialists, participate in the mission's second planned session of extravehicular activity (EVA), as construction resumes on the International Space Station. Among other tasks, Forrester and Swanson removed all of the launch locks holding the 10-foot-wide solar alpha rotary joint in place and began the solar array retraction. Tethered to his Extravehicular Mobility Unit (EMU) spacesuit, a hockey-stick-shaped tool wrapped in insulating tape, is visible in front of Swanson.

  16. Forrester prepares to retract the P6 Truss STBD SAW during EVA 2

    NASA Image and Video Library

    2007-06-13

    S117-E-07232 (13 June 2007) --- Astronauts Patrick Forrester and Steven Swanson (out of frame), both STS-117 mission specialists, participate in the mission's second planned session of extravehicular activity (EVA), as construction resumes on the International Space Station. Among other tasks, Forrester, seen here perched on the mobile foot restraint connected to the Canadian-built remote manipulator system (RMS), and Swanson removed all of the launch locks holding the 10-foot-wide solar alpha rotary joint in place and began the solar array retraction.

  17. Swanson during EVA 26

    NASA Image and Video Library

    2014-04-23

    ISS039-E-014893 (22 April 2014) --- NASA astronaut Steve Swanson is pictured during a spacewalk to replace a failed backup computer relay box in the S0 truss of the International Space Station on April 22, 2014. He was accompanied on the spacewalk by fellow Flight Engineer Rick Mastracchio of NASA, who can be seen as a tiny figure anchored several yards away reflected in Swanson's helmet visor.

  18. Swanson works on the P6 Truss during EVA 2

    NASA Image and Video Library

    2007-06-14

    S117-E-07332 (13 June 2007) --- Astronauts Steven Swanson and Patrick Forrester (out of frame), both STS-117 mission specialists, participate in the mission's second planned session of extravehicular activity (EVA), as construction resumes on the International Space Station. Among other tasks, Forrester and Swanson removed all of the launch locks holding the 10-foot-wide solar alpha rotary joint in place and began the solar array retraction.

  19. Biomechanical validation of finite element models for two silicone metacarpophalangeal joint implants.

    PubMed

    Hussein, A I; Stranart, J C; Meguid, S A; Bogoch, E R

    2011-02-01

    Silicone implants are used for prosthetic arthroplasty of metacarpophalangeal (MCP) joints severely damaged by rheumatoid arthritis. Different silicone elastomer MCP implant designs have been developed, including the Swanson and the NeuFlex implants. The goal of this study was to compare the in vitro mechanical behavior of Swanson and NeuFlex MCP joint implants. Three-dimensional (3D) finite element (FE) models of the silicone implants were modeled using the commercial software ANSYS and subjected to angular displacement from 0 deg to 90 deg. FE models were validated using mechanical tests of implants incrementally bent from 0 deg to 90 deg in a joint simulator. Swanson size 2 and 4 implants were compared with NeuFlex size 10 and 30 implants, respectively. Good agreement was observed throughout the range of motion for the flexion bending moment derived from 3D FE models and mechanical tests. From 30 deg to 90 deg, the Swanson 2 demonstrated a greater resistance to deformation than the NeuFlex 10 and required a greater bending moment for joint flexion. For larger implant sizes, the NeuFlex 30 had a steeper moment-displacement curve, but required a lower moment than the Swanson 4, due to implant preflexion. On average, the stress generated at the implant hinge from 30 deg to 90 deg was lower in the NeuFlex than in the Swanson. On average, starting from the neutral position of 30 deg for the preflexed NeuFlex implant, higher moments were required to extend the NeuFlex implants to 0 deg compared with the Swanson implants, which returned spontaneously to resting position. Implant toggling within the medullary canals was less in the NeuFlex than in the Swanson. The differential performance of these implants may be useful in implant selection based on the preoperative condition(s) of the joint and specific patient functional needs.

  20. Swanson moves to the S3/S4 Truss during STS-117 EVA 2

    NASA Image and Video Library

    2007-06-13

    S117-E-07264 (13 June 2007) --- Astronauts Steven Swanson and Patrick Forrester (out of frame), both STS-117 mission specialists, participate in the mission's second planned session of extravehicular activity (EVA), as construction resumes on the International Space Station. Among other tasks, Forrester and Swanson removed all of the launch locks holding the 10-foot-wide solar alpha rotary joint in place and began the solar array retraction.

  1. Swanson on Middeck (MDDK)

    NASA Image and Video Library

    2009-03-16

    S119-E-006168 (16 March 2009) --- Astronaut Steve Swanson, STS-119 mission specialist, reads a procedures checklist while working on the middeck of Space Shuttle Discovery during flight day two activities.

  2. View of Swanson working on the S3 Truss for STS-117 EVA2 during Joint Operations with Expedition 15

    NASA Image and Video Library

    2007-06-14

    ISS015-E-12063 (13 June 2007) --- Astronauts Steven Swanson and Patrick Forrester (out of frame), both STS-117 mission specialists, participate in the mission's second planned session of extravehicular activity (EVA), as construction resumes on the International Space Station. Among other tasks, Forrester and Swanson removed all of the launch locks holding the 10-foot-wide solar alpha rotary joint in place and began the solar array retraction.

  3. Swanson and Forrester prepare to retract the P6 Truss STBD 2B SAW during EVA 2

    NASA Image and Video Library

    2007-06-13

    S117-E-07246 (13 June 2007) --- Astronauts Steven Swanson and Patrick Forrester (at left, partially out of frame), both STS-117 mission specialists, participate in the mission's second planned session of extravehicular activity (EVA), as construction resumes on the International Space Station. Among other tasks, Forrester and Swanson removed all of the launch locks holding the 10-foot-wide solar alpha rotary joint in place and began the solar array retraction.

  4. Gerst and Swanson perform blood draw in Columbus module

    NASA Image and Video Library

    2014-06-04

    Astronaut Alexander Gerst,Expedition 40 flight engineer (background),and Expedition 40 Commander Steve Swanson are photographed performing blood sample collection in the Columbus module as part of HRF Generic Frozen Blood Collection Operations.

  5. Swanson signs Mission Patch in A/L

    NASA Image and Video Library

    2014-05-13

    ISS039-E-020710 (13 May 2014) --- NASA astronaut Steve Swanson, Expedition 39 flight engineer about to become Expedition 40 commander, signs a wall in the Quest airlock of the International Space Station after mounting his crew patch, continuing a tradition of station crew members who have participated in space walks on their respective flights. A short time later, Swanson took over command of the orbital outpost upon the departure of Expedition 39 Commander Koichi Wakata of the Japan Aerospace Exploration Agency (JAXA) and Flight Engineers Mikhail Tyurin of Roscosmos and Rick Mastracchio of NASA.

  6. Swanson in the US Lab

    NASA Image and Video Library

    2014-04-18

    ISS039-E-013158 (18 April 2014) --- In the U.S. lab Destiny on the Earth-orbiting International Space Station, Expedition 39 Flight Engineer Steve Swanson of NASA works on WRS condensate pumping, using the high flow water transfer pump.

  7. Swanson in Node 2 with ACE samples

    NASA Image and Video Library

    2014-07-14

    ISS040-E-060673 (14 July 2014) --- NASA astronaut Steve Swanson, Expedition 40 commander, works with test samples for the Advanced Colloids Experiment (ACE) at a work station in the Harmony node of the International Space Station.

  8. Swanson configures LMM for CARA-Petri Plant Experiment

    NASA Image and Video Library

    2014-05-05

    ISS039-E-018472 (5 May 2014) --? NASA astronaut Steve Swanson, Expedition 39 flight engineer, works in the U.S. laboratory Destiny of the International Space Station, preparing the Light Microscopy Module (LMM) for a planet experiment.

  9. Swanson in

    NASA Image and Video Library

    2014-06-11

    ISS040-E-010261 (11 June 2014) --- NASA astronaut Steve Swanson, Expedition 40 commander, works with the Multi-user Drop Combustion Apparatus (MDCA) at a workstation in the Harmony node of the International Space Station. The MDCA contains hardware and software to conduct unique droplet combustion experiments in space.

  10. Swanson in

    NASA Image and Video Library

    2014-06-11

    ISS040-E-010258 (11 June 2014) --- NASA astronaut Steve Swanson, Expedition 40 commander, works with the Multi-user Drop Combustion Apparatus (MDCA) at a workstation in the Harmony node of the International Space Station. The MDCA contains hardware and software to conduct unique droplet combustion experiments in space.

  11. Acaba and Swanson in US Laboratory Destiny

    NASA Image and Video Library

    2009-03-20

    S119-E-006743 (20 March 2009) --- On the eve of a planned shared spacewalk, astronauts Steve Swanson (left) and Joseph Acaba, both STS-119 mission specialists, have a meeting in the Joint Airlock aboard the International Space Station, while linked to the Space Shuttle Discovery.

  12. STS-119 Extravehicular Activity (EVA) 1 Swanson in Extravehicular Mobility Unit (EMU)

    NASA Image and Video Library

    2009-03-19

    ISS018-E-041093 (19 March 2009) --- Astronaut Steve Swanson, STS-119 mission specialist, participates in the mission's first scheduled session of extravehicular activity (EVA) as construction and maintenance continue on the International Space Station. During the six-hour, seven-minute spacewalk, Swanson and astronaut Richard Arnold (out of frame), mission specialist, connected bolts to permanently attach the S6 truss segment to S5. The spacewalkers plugged in power and data connectors to the truss, prepared a radiator to cool it, opened boxes containing the new solar arrays and deployed the Beta Gimbal Assemblies containing masts that support the solar arrays.

  13. STS-119 Extravehicular Activity (EVA) 1 Swanson in Extravehicular Mobility Unit (EMU)

    NASA Image and Video Library

    2009-03-19

    ISS018-E-041098 (19 March 2009) --- Astronaut Steve Swanson, STS-119 mission specialist, participates in the mission's first scheduled session of extravehicular activity (EVA) as construction and maintenance continue on the International Space Station. During the six-hour, seven-minute spacewalk, Swanson and astronaut Richard Arnold (out of frame), mission specialist, connected bolts to permanently attach the S6 truss segment to S5. The spacewalkers plugged in power and data connectors to the truss, prepared a radiator to cool it, opened boxes containing the new solar arrays and deployed the Beta Gimbal Assemblies containing masts that support the solar arrays.

  14. STS-119 Extravehicular Activity (EVA) 1 Swanson waves to camera

    NASA Image and Video Library

    2009-03-19

    ISS018-E-041084 (19 March 2009) --- Astronaut Steve Swanson, STS-119 mission specialist, participates in the mission's first scheduled session of extravehicular activity (EVA) as construction and maintenance continue on the International Space Station. During the six-hour, seven-minute spacewalk, Swanson and astronaut Richard Arnold (out of frame), mission specialist, connected bolts to permanently attach the S6 truss segment to S5. The spacewalkers plugged in power and data connectors to the truss, prepared a radiator to cool it, opened boxes containing the new solar arrays and deployed the Beta Gimbal Assemblies containing masts that support the solar arrays.

  15. STS-119 Extravehicular Activity (EVA) 1 S6 Truss Umbilical Mate OPS

    NASA Image and Video Library

    2009-03-19

    S119-E-006673 (19 March 2009) --- Astronauts Steve Swanson (center) and Richard Arnold (partially obscured above Swanson), both STS-119 mission specialists, participate in the mission's first scheduled session of extravehicular activity (EVA) as construction and maintenance continue on the International Space Station. During the six-hour, seven-minute spacewalk, Swanson and Arnold connected bolts to permanently attach the S6 truss segment to S5. The spacewalkers plugged in power and data connectors to the truss, prepared a radiator to cool it, opened boxes containing the new solar arrays and deployed the Beta Gimbal Assemblies containing masts that support the solar arrays.

  16. Swanson, Wiseman and Gerst in Node 2

    NASA Image and Video Library

    2014-05-29

    ISS040-E-006033 (29 May 2014) --- NASA astronaut Steve Swanson (center), Expedition 40 commander; along with European Space Agency astronaut Alexander Gerst (left) and NASA astronaut Reid Wiseman, both flight engineers, give a “thumbs up” signal in the Harmony node of the International Space Station.

  17. Meta-Analysis and Inadequate Responders to Intervention: A Reply

    ERIC Educational Resources Information Center

    Swanson, H. Lee

    2012-01-01

    A meta-analysis by Tran, Sanchez, Arellano, and Swanson (2011) of the published RTI literature found that the magnitude of effect size (ES) between responders and low responders at posttest was significantly moderated by the pretest ES and the type of dependent measure administered, whereas no significant moderating effects were found in the mixed…

  18. Swanson during EVA 26

    NASA Image and Video Library

    2014-04-23

    ISS039-E-014846 (22 April 2014) --- NASA astronaut Steve Swanson is pictured during a spacewalk to replace a failed backup computer relay box in the S0 truss of the International Space Station on April 22, 2014. He was accompanied on the spacewalk by fellow Flight Engineer Rick Mastracchio of NASA.

  19. Swanson during Day 2 of CDRA IFM

    NASA Image and Video Library

    2014-04-09

    ISS039-E-010367 (9 April 2014) --- In the Kibo laboratory aboard the International Space Station, Expedition 39 Flight Engineer Steve Swanson works during in-flight maintenance to mate electrical connectors in Tranquility's Carbon Dioxide Removal Assembly (CDRA). The image was taken during the second day of CDRA in-flight maintenance.

  20. Swanson uses the BMMD in the SM

    NASA Image and Video Library

    2014-03-31

    ISS039-E-008066 (30 March 2014) --- NASA astronaut Steve Swanson, Expedition 39 flight engineer, participates in body mass measurement/Russian biomedical routine assessments in the Zvezda Service Module of the International Space Station. Looking on is Russian cosmonaut Alexander Skvortsov, flight engineer representing the Russian Federal Space Agency (Roscosmos).

  1. STS-117 Crew Training during suited PI/DO Prep in CCT-II mockup

    NASA Image and Video Library

    2006-08-03

    JSC2006-E-32665 (3 Aug. 2006) --- Astronaut Steven R. Swanson, STS-117 mission specialist, participates in a training session in the crew compartment trainer (CCT-2) in the Space Vehicle Mockup Facility at Johnson Space Center. Swanson is wearing a training version of his shuttle launch and landing suit.

  2. Swanson and Mastracchio during EMU Fit Check in the A/L

    NASA Image and Video Library

    2014-04-17

    ISS039-E-013152 (17 April 2014) --- Inside the Quest airlock of the International Space Station, NASA astronauts Steve Swanson (left) and Rick Mastracchio, both Expedition 39 flight engineers, participate in a dress rehearsal for an upcoming spacewalk during which they are to replace a failed backup computer relay box in the S0 truss.

  3. Using Concepts in Literature-based Discovery: Simulating Swanson's Raynaud-Fish Oil and Migraine-Magnesium Discoveries.

    ERIC Educational Resources Information Center

    Weeber, Marc; Klein, Henny; de Jong-van den Berg, Lolkje T. W.; Vos, Rein

    2001-01-01

    Proposes a two-step model of discovery in which new scientific hypotheses can be generated and subsequently tested. Applying advanced natural language processing techniques to find biomedical concepts in text, the model is implemented in a versatile interactive discovery support tool. This tool is used to successfully simulate Don R. Swanson's…

  4. The Beliefs and Practices of Canadian Teachers about Including Students with Special Needs in their Regular Elementary Classrooms

    ERIC Educational Resources Information Center

    Jordan, Anne; Stanovich, Paula

    2004-01-01

    While considerable research has been directed at examining the effectiveness of placement for exceptional students, few studies have examined the instructional characteristics which contribute to the success or failure of these students included in regular classrooms (Swanson & Hoskyn, 1999; Swanson, Hoskyn & Lee, 1999). Over the last decade we…

  5. Micro-Electro-Mechanical Systems (MEMS) Fabrication Course Projects Review for FY15

    DTIC Science & Technology

    2015-09-01

    TECHNICAL DOCUMENT 3298 September 2015 Micro-Electro-Mechanical Systems (MEMS) Fabrication Course Projects Review for FY15 Paul D. Swanson...Naval Warfare Systems Center Pacific (SSC Pacific), San Diego, CA. SSC Pacific’s Naval Innovative Science and Engineering (NISE) Program provided...for Miniaturized Flow Cytometer o Howard Dyckman: 71730 Infrared Waveguides o Teresa Emery: 55360 Bistable MEMS systems for Energy

  6. The Transfer of Learning Process: Before, during, and after Educational Programs.

    ERIC Educational Resources Information Center

    Fox, Robert D.; And Others

    1994-01-01

    Includes "Planning Continuing Education to Foster the Transfer of Learning" (Fox); "Transfer Analysis" (Sleezer); "From the Classroom to the Real World" (Nolan); "Help Them Use What They Learn" (Cheek, Campbell); "After Educational Programs" (Kiener); "Measuring Transfer of Learning" (Swanson, Nijhof); and "Measuring Transfer of Learning or So…

  7. Flexible Design and Manufacturing Systems for Automotive Components and Sheet Metal Parts

    DTIC Science & Technology

    1999-10-01

    sometimes shocking discoveries you will make, discoveries that can help you avoid potential crises down the road if you take the necessary steps now...ISSUE Guest Lecture John Swanson, VP Qualcomm 10-Feb Fast, Flexible, Lilly, US Robotics, Economist, Upton & Agile Manufacturing Readings

  8. Transition probabilities for non self-adjoint Hamiltonians in infinite dimensional Hilbert spaces

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bagarello, F., E-mail: fabio.bagarello@unipa.it

    In a recent paper we have introduced several possible inequivalent descriptions of the dynamics and of the transition probabilities of a quantum system when its Hamiltonian is not self-adjoint. Our analysis was carried out in finite dimensional Hilbert spaces. This is useful, but quite restrictive since many physically relevant quantum systems live in infinite dimensional Hilbert spaces. In this paper we consider this situation, and we discuss some applications to well known models, introduced in the literature in recent years: the extended harmonic oscillator, the Swanson model and a generalized version of the Landau levels Hamiltonian. Not surprisingly we willmore » find new interesting features not previously found in finite dimensional Hilbert spaces, useful for a deeper comprehension of this kind of physical systems.« less

  9. STS-117 Swanson performs the PMDIS in the U.S. Laboratory

    NASA Image and Video Library

    2007-06-12

    ISS015-E-11968 (12 June 2007) --- Astronaut Steven Swanson, STS-117 mission specialist, works with the Perceptual Motor Deficits in Space (PMDIS) experiment in the Destiny laboratory of the International Space Station. The PMDIS experiment will measure the decline in hand-eye coordination of shuttle astronauts while on orbit. These measurements will be used to evaluate various mechanisms thought to be responsible for the decline.

  10. A Determination of the Minimum Frequency Requirements for a PATRIOT Battalion UHF Communication System.

    DTIC Science & Technology

    1982-12-01

    a computer program which simulates the PATRIOT battalion UH1F communication system. *.-.The detailed description of how the model performs this...the Degree of Master of Science .AI . j tf ti on-i by 5 , .... . :it Lard/or Gregory H. Swanson DLt Captain USA Graduate Computer Science I...5 Model Application..... . . . .. .. . . .. .. . . 6 Thesnis Overviev ....... o.000000000000000000000. .6 Previous Studies

  11. Forrester works at the P6 Truss during EVA 2 on STS-117 Mission

    NASA Image and Video Library

    2007-06-14

    S117-E-07313 (13 June 2007) --- Astronauts Patrick Forrester and Steven Swanson (out of frame), both STS-117 mission specialists, participate in the mission's second planned session of extravehicular activity (EVA), as construction resumes on the International Space Station. Among other tasks, Forrester and Swanson removed all of the launch locks holding the 10-foot-wide solar alpha rotary joint in place and began the solar array retraction.

  12. Forrester works at the P6 Truss during EVA 2 on STS-117 Mission

    NASA Image and Video Library

    2007-06-14

    S117-E-07315 (13 June 2007) --- Astronauts Patrick Forrester and Steven Swanson (out of frame), both STS-117 mission specialists, participate in the mission's second planned session of extravehicular activity (EVA), as construction resumes on the International Space Station. Among other tasks, Forrester and Swanson removed all of the launch locks holding the 10-foot-wide solar alpha rotary joint in place and began the solar array retraction.

  13. Forrester moves to the S3/S4 Truss during STS-117 EVA 2

    NASA Image and Video Library

    2007-06-13

    S117-E-07258 (13 June 2007) --- Astronauts Patrick Forrester and Steven Swanson (out of frame), both STS-117 mission specialists, participate in the mission's second planned session of extravehicular activity (EVA), as construction resumes on the International Space Station. Among other tasks, Forrester and Swanson removed all of the launch locks holding the 10-foot-wide solar alpha rotary joint in place and began the solar array retraction.

  14. Regional discrimination studies: Phase III. Scientific report No. 3

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bonner, J.; Herrin, E.; Sorrells, G.G.

    1997-03-01

    This report consists of three parts. Part 1, `Construction of Regional Ground Truth Data Bases Using Seismic And Infrasound Data` is by Gordon Sorrells, Eugene Herrin, and Jessie Bonner with contributions from Jack Swanson, Sarah Deering and Angela Maddox. Part 2, `Seismic And Infrasound Data Observations At TXAR` is by Jessie Bonner, Sarah Deering, Tao Liu, Jack Swanson and Ileana Tibuleac. Part 3, consists of the Acknowledgments called for by the contract.

  15. Views on the Oberg-Manske-Tonkin Classification System for Congenital Anomalies of the Hand and Upper Limb.

    PubMed

    Lowry, R Brian; Bedard, Tanya; Kiefer, Gerhard N; Sass, Kimberly R

    2017-05-01

    A new classification system was proposed by Tonkin et al as a replacement for the Swanson/International Federation of Societies for Surgery of the Hand system. We have reviewed their aims and have pointed out a number of problems that will make it difficult to be universally accepted. Copyright © 2017 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.

  16. Diplomas Count: An Essential Guide to Graduation Policy and Rates

    ERIC Educational Resources Information Center

    Edwards, Virginia B., Ed.

    2006-01-01

    "Education Week" provides a weekly review of state and federal K-12 education policy news. In this issue it offers detailed data on graduation rates across the 50 states and the District of Columbia, and in the nation's 50 largest school districts. The analysis is based on the Cumulative Promotion Index developed by Christopher B. Swanson, the…

  17. jsc2014e024978

    NASA Image and Video Library

    2014-03-06

    At the Kremlin Wall in Moscow, Expedition 39/40 Flight Engineer Steve Swanson of NASA lays flowers in a tribute to Russian space icons who are interred there as part of ceremonial activities. Swanson, Flight Engineer Oleg Artmeyev of Roscosmos and Soyuz Commander Alexander Skvortsov of Roscosmos are preparing for their launch to the International Space Station from the Baikonur Cosmodrome in Kazakhstan March 26, Kazakh time, in their Soyuz TMA-12M spacecraft for a six-month mission. NASA/Stephanie Stoll

  18. Forrester works on the S1/S3 Trusses during EVA 2 on STS-117 Mission

    NASA Image and Video Library

    2007-06-14

    S117-E-07217 (13 June 2007) --- Astronauts Patrick Forrester and Steven Swanson (out of frame), both STS-117 mission specialists, participate in the mission's second planned session of extravehicular activity (EVA), as construction resumes on the International Space Station. Among other tasks, Forrester and Swanson removed all of the launch locks holding the 10-foot-wide solar alpha rotary joint in place and began the solar array retraction.

  19. Forrester works at the S3/S4 Trusses during EVA 2 on STS-117 Mission

    NASA Image and Video Library

    2007-06-13

    S117-E-07190 (13 June 2007) --- Astronauts Patrick Forrester and Steven Swanson (out of frame), both STS-117 mission specialists, participate in the mission's second planned session of extravehicular activity (EVA), as construction resumes on the International Space Station. Among other tasks, Forrester and Swanson removed all of the launch locks holding the 10-foot-wide solar alpha rotary joint in place and began the solar array retraction.

  20. Forrester works at the S3/S4 Trusses during EVA 2 on STS-117 Mission

    NASA Image and Video Library

    2007-06-13

    S117-E-07289 (13 June 2007) --- Astronauts Patrick Forrester and Steven Swanson (out of frame), both STS-117 mission specialists, participate in the mission's second planned session of extravehicular activity (EVA), as construction resumes on the International Space Station. Among other tasks, Forrester and Swanson removed all of the launch locks holding the 10-foot-wide solar alpha rotary joint in place and began the solar array retraction.

  1. Forrester works at the S3/S4 Trusses during EVA 2 on STS-117 Mission

    NASA Image and Video Library

    2007-06-13

    S117-E-07286 (13 June 2007) --- Astronauts Patrick Forrester and Steven Swanson (out of frame), both STS-117 mission specialists, participate in the mission's second planned session of extravehicular activity (EVA), as construction resumes on the International Space Station. Among other tasks, Forrester and Swanson removed all of the launch locks holding the 10-foot-wide solar alpha rotary joint in place and began the solar array retraction.

  2. Quality Counts 2007: From Cradle to Career--Connecting American Education from Birth to Adulthood

    ERIC Educational Resources Information Center

    Education Week, 2007

    2007-01-01

    "Quality Counts 2007" begins to track state efforts to create seamless education systems from early childhood to the world of work. This special issue of "Education Week" includes the following articles: (1) Improving Children's Chances (Lynn Olson); (2) Spanning a Lifetime (Christopher B. Swanson); (3) Breaking the Cycle of Poverty (Lynn Olson);…

  3. The Impact of Pore Structure on Densification Efficiency of 2-D Carbon-Carbon Composites and Its Relationship to Mechanical Properties

    DTIC Science & Technology

    2011-03-01

    Allcomp Inc . The Impact of Pore Structure on Densification...topic. I would also like to acknowledge and thank Allcomp , Inc . for supplying the materials for all the tests in this study. I am also very... Allcomp , Inc . who assisted in other ways throughout this effort. -David Swanson                             Swanson 4    Abstract The

  4. STS-117 Astronauts Patrick Forrester and Steven Swanson During EVA

    NASA Technical Reports Server (NTRS)

    2007-01-01

    STS-117 astronauts and mission specialists Patrick Forrester and Steven Swanson (out of frame), participated in the second Extra Vehicular Activity (EVA) as construction resumed on the International Space Station (ISS). Among other tasks, the two removed all of the launch locks holding the 10 foot wide solar alpha rotary joint in place and began the solar array retraction. The primary mission objective was the installment of the second and third starboard truss segments (S3 and S4).

  5. Japanese Economic Victory Over America: Fact or Fiction

    DTIC Science & Technology

    1990-04-01

    together. 8 ENDNOTES CHAPTER I 1. Kobayashi Kaorli, "That Yen for Power," Japan Quarterly, Vol. 36, No. 2, April-June 1989, p. 217. 2. S. Prakarah Sethi... Nobuaki Namiki;and Carl L. Swanson, The False Promise cf the Japanese Miracle, p. 8. 3. Ibid., p. 7. 4. Ibid., p. 7. 5. U. S. Central Intelligence...Parakash S. Sethi; Nobuaki Namiki; and Carl E. Swanson, The False Promise of the Japanese Miracle, p. 43. 6. U.S. Department of Labor, p. 15. 7. Akino

  6. 2011 NASA Day at the Capitol

    NASA Image and Video Library

    2011-02-10

    Astronaut Steven Swanson (front) speaks to members of the Mississippi Senate in chambers, with Lt. Gov. Phil Bryant presiding (rear), during NASA Day at the Capitol in Jackson on Feb. 10. Swanson was joined at the podium by Sen. David Baria, D-Bay St. Louis (l to r), NASA Shared Services Center Executive Director Rick Arbuthnot, Stennis Director Patrick Scheuermann, Sen. Ezell Lee, D-Picayune, and Sen. Billy Hewes, R-Gulfport. Baria, Lee and Hewes all are members of the Mississippi Senate Gulf Coast delegation.

  7. Maggie Creek Water Quality Data

    EPA Pesticide Factsheets

    These data are standard water quality parameters collected for surface water condition analysis (for example pH, conductivity, DO, TSS).This dataset is associated with the following publication:Kozlowski, D., R. Hall , S. Swanson, and D. Heggem. Linking Management and Riparian Physical Functions to Water Quality and Aquatic Habitat. JOURNAL OF WATER RESOURCES PLANNING AND MANAGEMENT. American Society of Civil Engineers (ASCE), Reston, VA, USA, 8(8): 797-815, (2016).

  8. jsc2014e024976

    NASA Image and Video Library

    2014-03-06

    Expedition 39/40 Flight Engineer Steve Swanson of NASA (front, left), Alexander Samokutyaev of Roscosmos (front, center) and Oleg Artemyev (front, right) arrive at Red Square in Moscow by the Kremlin March 6 for the ceremonial laying of flowers at the Kremlin Wall in tribute to Russian space icons who are interred there. Swanson, Skvortsov and Artemyev are preparing for their launch to the International Space Station from the Baikonur Cosmodrome in Kazakhstan March 26, Kazakh time, in their Soyuz TMA-12M spacecraft for a six-month mission. NASA/Stephanie Stoll

  9. jsc2014e025973

    NASA Image and Video Library

    2014-03-13

    Flying from their training base in Star City, Russia to their launch site at the Baikonur Cosmodrome in Kazakhstan, Expedition 39/40 Flight Engineer Steve Swanson of NASA (left) and Flight Engineer Oleg Artemyev of the Russian Federal Space Agency (Roscosmos; right) apply a sticker bearing their mission insignia to the wall of their plane March 13. Swanson, Artemyev and Soyuz Commander Alexander Skvortsov of Roscosmos (hidden) are preparing for their launch to the International Space Station March 26, Kazakh time, in their Soyuz TMA-12M spacecraft for a six-month mission. NASA/Victor Zelentsov

  10. A Latent Transition Analysis of English Learners with Reading Disabilities: Do Measures of Cognition Add to Predictions of Late Emerging Risk Status?

    ERIC Educational Resources Information Center

    Swanson, H. Lee

    2017-01-01

    The purpose of this cohort sequential study was to extend previously reported latent transition analyses conducted by Swanson, Kudo, and Guzman-Orth (2016) by determining the role of cognitive measures in identifying English learners (EL) at risk for late emerging reading disabilities (LERD). To this end, EL students (N = 450) in Grades 1, 2, and…

  11. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (84th, Washington, DC, August 5-8, 2001). Religion and Media Interest Group.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Religion and Media Interest Group section of the proceedings contains the following 4 selected papers: "'Where All Things Are Pure and of Good Report': The Doctrinal Theology, Religious Practice, and Media Manipulation of the Christian Science Church" (Douglas J. Swanson); "Religion and Topoi in the News: An Analysis of the…

  12. STS-119 Extravehicular Activity (EVA) 1 Translate and Ingress

    NASA Image and Video Library

    2009-03-19

    S119-E-006688 (19 March 2009) --- Astronaut Steve Swanson, STS-119 mission specialist, participates in the mission's first scheduled session of extravehicular activity (EVA) as construction and maintenance continue on the International Space Station. During the six-hour, seven-minute spacewalk, Swanson and astronaut Richard Arnold (out of frame), mission specialist, connected bolts to permanently attach the S6 truss segment to S5. The spacewalkers plugged in power and data connectors to the truss, prepared a radiator to cool it, opened boxes containing the new solar arrays and deployed the Beta Gimbal Assemblies containing masts that support the solar arrays.

  13. jsc2014e025974

    NASA Image and Video Library

    2014-03-13

    Flying from their training base in Star City, Russia to their launch site at the Baikonur Cosmodrome in Kazakhstan, Expedition 39/40 Soyuz Commander Alexander Skvortsov of the Russian Federal Space Agency (Roscosmos; left), Flight Engineer Steve Swanson of NASA (center) and Flight Engineer Oleg Artemyev of Roscosmos (right) pose for pictures March 13 next to the wall of the plane bearing a newly applied sticker with their mission insignia. Swanson, Artemyev and Skvortsov are preparing for their launch to the International Space Station March 26, Kazakh time, in their Soyuz TMA-12M spacecraft for a six-month mission. NASA/Victor Zelentsov

  14. STS-119 Extravehicular Activity (EVA) 1 S6 Truss Umbilical Mate OPS

    NASA Image and Video Library

    2009-03-19

    S119-E-006674 (19 March 2009) --- Astronaut Steve Swanson (center), STS-119 mission specialist, participates in the mission's first scheduled session of extravehicular activity (EVA) as construction and maintenance continue on the International Space Station. During the six-hour, seven-minute spacewalk, Swanson and astronaut Richard Arnold (out of frame), mission specialist, connected bolts to permanently attach the S6 truss segment to S5. The spacewalkers plugged in power and data connectors to the truss, prepared a radiator to cool it, opened boxes containing the new solar arrays and deployed the Beta Gimbal Assemblies containing masts that support the solar arrays.

  15. STS-119 Extravehicular Activity (EVA) 1 S6 Truss Umbilical Mate OPS

    NASA Image and Video Library

    2009-03-19

    S119-E-006675 (19 March 2009) --- Astronaut Steve Swanson (center right), STS-119 mission specialist, participates in the mission's first scheduled session of extravehicular activity (EVA) as construction and maintenance continue on the International Space Station. During the six-hour, seven-minute spacewalk, Swanson and astronaut Richard Arnold (out of frame), mission specialist, connected bolts to permanently attach the S6 truss segment to S5. The spacewalkers plugged in power and data connectors to the truss, prepared a radiator to cool it, opened boxes containing the new solar arrays and deployed the Beta Gimbal Assemblies containing masts that support the solar arrays.

  16. KSC-2009-2016

    NASA Image and Video Library

    2009-03-10

    CAPE CANAVERAL, Fla. – In the Operations and Checkout Building at NASA's Kennedy Space Center in Florida, STS-119 Mission Specialist Steve Swanson has the final fitting of his launch and entry suit. Swanson is making his second shuttle flight. The 14-day mission is the 28th to the International Space Station and the 125th space shuttle flight. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science. Liftoff of Discovery is scheduled for 9:20 p.m. EDT on March 11. Photo credit: NASA/Kim Shiflett

  17. 2005 Tri-Service Infrastructure Systems Conference and Exhibition

    DTIC Science & Technology

    2005-08-04

    Reclamation Irrigation/Flood Control Reservoirs • Bonny • Swanson • Enders • Harry Strunk • Hugh Butler • Keith Sebelius • Lovewell US Army Corps of...Water Quality – Mentor, Topeka, DeSoto • Irrigation – Waconda, Harlan County, Lovewell • Navigation Support – Milford, Tuttle Creek, Perry • Endangered...1977 LOVL ( Lovewell Reservoir): January 1, 1980 MILD (Milford Lake) August 24, 1964 Kansas City District US Army Corps of Engineers PRECIPATATION GAGES

  18. Metabolism, Mass Spectral Analysis and Mode of Action of Trichothecene Mycotoxins

    DTIC Science & Technology

    1988-10-12

    tissue, as well as depletion and mild necrosis of thymic lymphoid tissue. Two rats showed mild, acute necrosis of proximal renal tubular epithelium...toxicity in pigs. Res. in Vet. Sci. 31:131. Weaver GA, Hurt.z HJ, Mirocha CU, Bates FY, Behrens JC, Robison TS, and Swanson SP (1980) The failure of purified...by Professor Abraham Joffe. The problem was called alimentary toxic aleukia which affected (according to the chronicles ) thousands of people eating

  19. Interrelationships of Prenatal and Postnatal Growth, Hormones, Diet, and Breast Cancer

    DTIC Science & Technology

    2006-03-01

    Breslow NE, Day NE. Statistical methods in cancer research, vol. 1. The analysis of case-control studies, IARC Sci. Publ. 32, Lyon, IARC, 1980 . 9...weight (Ekbom et al, 1992; Innes et al, 2000; Michels et al, 1996; Sander- son et al, 1996). Conversely, high adolescent (Coates et al, 1999; Hislop et...Brinton and Swanson, 1992; Choi et al, 1978; Coates et al, 1999; Franceschi et al, 1996; Hislop et al, 1986; Le Marchand et al, 1988a; Pryor et al, 1989

  20. A Graph-Based Recovery and Decomposition of Swanson’s Hypothesis using Semantic Predications

    PubMed Central

    Cameron, Delroy; Bodenreider, Olivier; Yalamanchili, Hima; Danh, Tu; Vallabhaneni, Sreeram; Thirunarayan, Krishnaprasad; Sheth, Amit P.; Rindflesch, Thomas C.

    2014-01-01

    Objectives This paper presents a methodology for recovering and decomposing Swanson’s Raynaud Syndrome–Fish Oil Hypothesis semi-automatically. The methodology leverages the semantics of assertions extracted from biomedical literature (called semantic predications) along with structured background knowledge and graph-based algorithms to semi-automatically capture the informative associations originally discovered manually by Swanson. Demonstrating that Swanson’s manually intensive techniques can be undertaken semi-automatically, paves the way for fully automatic semantics-based hypothesis generation from scientific literature. Methods Semantic predications obtained from biomedical literature allow the construction of labeled directed graphs which contain various associations among concepts from the literature. By aggregating such associations into informative subgraphs, some of the relevant details originally articulated by Swanson has been uncovered. However, by leveraging background knowledge to bridge important knowledge gaps in the literature, a methodology for semi-automatically capturing the detailed associations originally explicated in natural language by Swanson has been developed. Results Our methodology not only recovered the 3 associations commonly recognized as Swanson’s Hypothesis, but also decomposed them into an additional 16 detailed associations, formulated as chains of semantic predications. Altogether, 14 out of the 19 associations that can be attributed to Swanson were retrieved using our approach. To the best of our knowledge, such an in-depth recovery and decomposition of Swanson’s Hypothesis has never been attempted. Conclusion In this work therefore, we presented a methodology for semi- automatically recovering and decomposing Swanson’s RS-DFO Hypothesis using semantic representations and graph algorithms. Our methodology provides new insights into potential prerequisites for semantics-driven Literature-Based Discovery (LBD). These suggest that three critical aspects of LBD include: 1) the need for more expressive representations beyond Swanson’s ABC model; 2) an ability to accurately extract semantic information from text; and 3) the semantic integration of scientific literature with structured background knowledge. PMID:23026233

  1. Real-Time Adaptive Control of Mixing in a Plane Shear Layer

    DTIC Science & Technology

    1994-02-02

    l’icoulement d’un fuide visqueux incompressible autour d’un cylinder fixe ou en rotation. Effet Magnus . J. Mdc. 14, 109-134. TANEDA, S. 1977 Visual study...Mokhtarian & Yokomizo 1990), and in lift enhancement schemes employing the Magnus effect (Swanson 1961). Rotation of all or part of a body may also have...coordinate system. In this work, the body-fitted grid is simply one of cylindrical polar coordinates and is time-independent, except for a = 3.25 where

  2. Development of the Wake Behind a Circular Cylinder Impulsively Started into Rotatory and Rectilinear Motion: Intermediate Rotation Rates

    DTIC Science & Technology

    1991-01-01

    cylindre fixe ou en rotation. Effet Magnus . J. Mec. 14, 109-134. Taneda, S. 1977 Visual study of unsteady separated flows around bodies. Prog. Aero...enhancement schemes employing the Magnus effect (Swanson 1961). Rotating all or part of a body may also have applications in active or feedback control of...and yt into the governing equations in the generalized coordinate system. In this study, the body-fitted grid is simply one of cylindrical polar

  3. Mechanical testing and finite element analysis of orthodontic teardrop loop.

    PubMed

    Coimbra, Maria Elisa Rodrigues; Penedo, Norman Duque; de Gouvêa, Jayme Pereira; Elias, Carlos Nelson; de Souza Araújo, Mônica Tirre; Coelho, Paulo Guilherme

    2008-02-01

    Understanding how teeth move in response to mechanical loads is an important aspect of orthodontic treatment. Treatment planning should include consideration of the appliances that will meet the desired loading of the teeth to result in optimized treatment outcomes. The purpose of this study was to evaluate the use of computer simulation to predict the force and the torsion obtained after the activation of tear drop loops of 3 heights. Seventy-five retraction loops were divided into 3 groups according to height (6, 7, and 8 mm). The loops were subjected to tensile load through displacements of 0.5, 1.0, 1.5, and 2.0 mm, and the resulting forces and torques were recorded. The loops were designed in AutoCAD software(2005; Autodesk Systems, Alpharetta, GA), and finite element analysis was performed with Ansys software(version 7.0; Swanson Analysis System, Canonsburg, PA). Statistical analysis of the mechanical experiment results was obtained by ANOVA and the Tukey post-hoc test (P < .01). The correlation test and the paired t test (P < .05) were used to compare the computer simulation with the mechanical experiment. The computer simulation accurately predicted the experimentally determined mechanical behavior of tear drop loops of different heights and should be considered an alternative for designing orthodontic appliances before treatment.

  4. Proposing a Formalised Model for Mindful Information Systems Offshoring

    NASA Astrophysics Data System (ADS)

    Costello, Gabriel J.; Coughlan, Chris; Donnellan, Brian; Gadatsch, Andreas

    The central thesis of this chapter is that mathematical economics can provide a novel approach to the examination of offshoring business decisions and provide an impetus for future research in the area. A growing body of research indicates that projected cost savings from IT offshoring projects are not being met. Furthermore, evidence suggests that decision-making processes have been more emotional than rational, and that many offshoring arrangements have been rushed into without adequate analysis of the true costs involved. Building on the concept of mindfulness and mindlessness introduced to the IS literature by Swanson and Ramiller, a cost equation is developed using “deductive reasoning rather than inductive study” in the tradition of mathematical economics. The model endeavours to capture a wide range of both the quantitative and qualitative parameters. Although the economic model is illustrated against the background of a European scenario, the theoretical framework is generic and applicable to organisations in any global location.

  5. Science and Technology Text Mining: Comparative Analysis of the Research Impact Assessment Literature and the Journal of the American Chemical Society

    DTIC Science & Technology

    2003-08-15

    Their analyses confirmed Swanson’s results, and showed that FISH OIL and EICOSAPENTAENOIC ACID (one of fish oil’s main chemical constituents) offered...therefore true candidates for discovery. They finally arrive at FISH OIL, and EICOSAPENTAENOIC ACID (one of fish oil’s main chemical constituents...CHEM 250 ; BIOPOLYMERS 242 ; LANGMUIR 239 ; MOL-PHYS 233 ; 24 PHYS-REV-B 232 ; ANAL-CHEM 225 ; INT-J-MASS-SPECTROM 222 ; NUCLEIC- ACIDS -RES 222 ; J

  6. Glacier Swap

    NASA Image and Video Library

    2014-05-16

    ISS040-E-000298 (16 May 2014) --- NASA astronaut Steve Swanson, Expedition 40 commander, works with the General Laboratory Active Cryogenic ISS Experiment Refrigerator (GLACIER) in the Destiny laboratory of the International Space Station.

  7. Glacier Swap

    NASA Image and Video Library

    2014-05-16

    ISS040-E-000297 (16 May 2014) --- NASA astronaut Steve Swanson, Expedition 40 commander, works with the General Laboratory Active Cryogenic ISS Experiment Refrigerator (GLACIER) in the Destiny laboratory of the International Space Station.

  8. Glacier Swap

    NASA Image and Video Library

    2014-05-16

    ISS040-E-000296 (16 May 2014) --- NASA astronaut Steve Swanson, Expedition 40 commander, works with the General Laboratory Active Cryogenic ISS Experiment Refrigerator (GLACIER) in the Destiny laboratory of the International Space Station.

  9. Using analog flow experiments to model morphologies developed during episodic dome growth: A case study of Mount St Helens, 1980-1986

    NASA Astrophysics Data System (ADS)

    Altman, K. M.; Teasdale, R.

    2009-12-01

    From 1980 to 1986 the dacite dome at Mount St. Helens was emplaced as a series of 17 events, identified by different growth rates, volumes, height to diameter ratios, emplacement rates, surface textures and dome morphologies (Swanson, 1989). Rates of emplacement characterize three periods; between October 18, 1980 and the end of 1981 the growth rate was 1.8 x 10^6 m^3/month; between March 1982 and March 1984 the growth rate was 1.3 x 10^6 m^3/month; followed by a growth rate of 0.62 x 10^6 m^3/month until the end of the emplacement events in 1986 (Swanson, 1989). The shape of the dome changed from 1980 to 1986 as a function of magma viscosity, tensile strength of the hot core, and thickness of the outer shell (Swanson, 1989). The height to diameter ratios (h:d) recorded throughout the growth of the dome have been used to quantify the changes in the shape of the dome. The dome was flatter during the first period of emplacement when larger volumes kept the dome hotter and hindered the formation of a thick, cool outer crust (Swanson, 1989). Once the growth rate slowed by June 1981, a thick skin had formed and allowed the dome to steepen (Swanson, 1989). Analog models presented here aim to reproduce the emplacement of the domes based on observations and data recorded at Mount St. Helens from 1980 to 1986. Flow experiments use a slurry of PEG (poly-ethelyne glycol) mixed with kaolin powder that is pumped into a tank of cold water (Fink and Griffiths, 1998). PEG is used because it is liquid at room temperature and solidifies in the cold water. Kaolin powder is added to the PEG to simulate the viscosity of the dacite domes. The observed and recorded data from Mount St. Helens are used to constrain analog flow model parameters such as slope, effusion rate, and PEG viscosity in an attempt to recreate the dome morphologies observed in the 1980 to 1986 episodes. As expected, dome morphology in experiments varies with the crustal thickness developed during experiments. The thickness of dome crust increases when the difference between water temperature and the slurry are large. Dome crust thickness controls the h:d ratio, which are used here to characterize dome morphology. The h:d ratio of experiments are within 5% of those measured at Mount St. Helens, so are considered good representations of dome growth events. Ongoing work investigates multiple episodes of dome emplacement using solid structures in the tanks to represent previously emplaced dome edifices.

  10. OH Vision Test

    NASA Image and Video Library

    2014-06-02

    ISS040-E-006107 (2 June 2014) --- NASA astronaut Steve Swanson, Expedition 40 commander, performs a visual exam using an eye chart (out of frame) in the Destiny laboratory of the International Space Station.

  11. Swans replacing filter in U.S. Laboratory

    NASA Image and Video Library

    2014-07-15

    ISS040-E-064628 (15 July 2014) --- NASA astronaut Steve Swanson, Expedition 40 commander, replaces filters in the Potable Water Dispenser (PWD) in the Destiny laboratory of the International Space Station.

  12. Aortopulmonary window

    MedlinePlus

    ... del Nido PJ, Swanson SJ, eds. Sabiston and Spencer Surgery of the Chest . 9th ed. Philadelphia, PA: ... MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. Congenital Heart Defects Read ...

  13. View of Forrester working on ISS construction during STS-117 EVA2

    NASA Image and Video Library

    2007-06-13

    ISS015-E-12018 (13 June 2007) --- Anchored to a foot restraint on the Space Station Remote Manipulator System (SSRMS) or Canadarm2, astronaut Patrick Forrester, STS-117 mission specialist, participates in the mission's second planned session of extravehicular activity (EVA), as construction resumes on the International Space Station. Among other tasks, Forrester and astronaut Steven Swanson (out of frame), mission specialist, removed all of the launch locks holding the 10-foot-wide solar alpha rotary joint in place and began the solar array retraction.

  14. Swanson working in Airlock

    NASA Image and Video Library

    2014-06-05

    ISS040-E-007682 (5 June 2014) --- NASA astronaut Reid Wiseman, Expedition 40 flight engineer, uses a computer while working with an Extravehicular Mobility Unit (EMU) spacesuit in the Quest airlock of the International Space Station.

  15. Cargo Transfer operations

    NASA Image and Video Library

    2014-08-21

    ISS040-E-103985 (21 Aug. 2014) --- NASA astronaut Steve Swanson, Expedition 40 commander, is pictured during cargo transfer operations in the "Georges Lemaitre" Automated Transfer Vehicle-5 (ATV-5) currently docked with the International Space Station.

  16. Hemangioma

    MedlinePlus

    ... 38. Review Date 10/24/2016 Updated by: David L. Swanson, MD, Vice Chair of Medical Dermatology, Associate Professor of Dermatology, Mayo Medical School, Scottsdale, AZ. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the ...

  17. Pityriasis alba

    MedlinePlus

    ... 10. Review Date 5/2/2017 Updated by: David L. Swanson, MD, Vice Chair of Medical Dermatology, Associate Professor of Dermatology, Mayo Medical School, Scottsdale, AZ. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial ...

  18. Spider angioma

    MedlinePlus

    ... 650. Review Date 10/24/2016 Updated by: David L. Swanson, MD, Vice Chair of Medical Dermatology, Associate Professor of Dermatology, Mayo Medical School, Scottsdale, AZ. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the ...

  19. Rhinophyma

    MedlinePlus

    ... 7. Review Date 10/24/2016 Updated by: David L. Swanson, MD, Vice Chair of Medical Dermatology, Associate Professor of Dermatology, Mayo Medical School, Scottsdale, AZ. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the ...

  20. Migraines and Gastrointestinal Problems: Is There a Link?

    MedlinePlus

    ... there a link? Is there any link between migraines and gastrointestinal problems? Answers from Jerry W. Swanson, ... link. Nausea and vomiting are often associated with migraine attacks. In young children, several syndromes that cause ...

  1. Genetics Home Reference: lissencephaly with cerebellar hypoplasia

    MedlinePlus

    ... on PubMed or Free article on PubMed Central Ross ME, Swanson K, Dobyns WB. Lissencephaly with cerebellar ... AA, Abdel-Salam G, Koeller HB, Ilkin Y, Ross ME, Dobyns WB, Gleeson JG. Identification of a ...

  2. Fungal nail infection

    MedlinePlus

    ... 268. Review Date 10/24/2016 Updated by: David L. Swanson, MD, Vice Chair of Medical Dermatology, Associate Professor of Dermatology, Mayo Medical School, Scottsdale, AZ. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the ...

  3. Effects of MPH-OROS on the organizational, time management, and planning behaviors of children with ADHD.

    PubMed

    Abikoff, Howard; Nissley-Tsiopinis, Jenelle; Gallagher, Richard; Zambenedetti, Maurizio; Seyffert, Michael; Boorady, Roy; McCarthy, John

    2009-02-01

    To evaluate the effects of stimulant medication on organizational, time management, and planning (OTMP) in children with attention-deficit/hyperactivity disorder (ADHD) and ascertain whether OTMP is normalized with medication. Participants included 19 stimulant-naïve children with ADHD (aged 8-13 years) and impaired OTMP functioning, defined as greater than 1 SD below norms on the Children's Organizational Skills Scale. A double-blind, placebo-controlled, crossover design, with 4 weeks of each condition, evaluated medication (methylphenidate-osmotic-release oral system [MPH-OROS]) effects on OTMP, based on the parent and teacher versions of the Children's Organizational Skills Scale. The parent and teacher Swanson, Nolan, and Pelham, Version IV, rating scales assessed ADHD symptoms. "Not impaired" in OTMP was defined as no longer meeting study entry criteria, and "not impaired" in ADHD symptoms was defined as having mean Swanson, Nolan, and Pelham, Version IV, scores of < or = 1.0. MPH-OROS significantly improved children's OTMP behaviors. These improvements were correlated with significant reductions in ADHD symptoms. However, most of the children (61%) continued to show significant OTMP impairments on MPH-OROS. The MPH-OROS reduced children's OTMP deficits, and these improvements were associated with improvements in ADHD symptoms. Some children remained impaired in OTMP even after effective stimulant treatment of ADHD symptoms. These youngsters may require other treatments that target OTMP deficits.

  4. KSC-08pd0703

    NASA Image and Video Library

    2008-03-11

    KENNEDY SPACE CENTER, FLA. -- In the Firing Room of the Launch Control Center at NASA's Kennedy Space Center, John Swanson (center), Thermal Protection System manager with United Space Alliance, receives the Flow Award from Shuttle Launch Director Mike Leinbach (right) after the successful launch of space shuttle Endeavour on the STS-123 mission. At left is NASA Flow Director for Endeavour Ken Tenbusch. Liftoff of Endeavour was on time at 2:28 a.m. EDT. Endeavour's crew will make a record-breaking 16-day mission to the International Space Station and deliver the first section of the Japan Aerospace Exploration Agency's Kibo laboratory and the Canadian Space Agency's two-armed robotic system, Dextre. Photo credit: NASA/Kim Shiflett

  5. Hot tub folliculitis

    MedlinePlus

    ... RG. Folliculitis. In: Lebwohl MG, Heymann WR, Berth-Jones J, Coulson I, eds. Treatment of Skin Disease: Comprehensive Therapeutic Strategies . 4th ed. Philadelphia, PA: Elsevier; 2014:chap 83. Review Date 10/24/2016 Updated by: David L. Swanson, MD, Vice Chair ...

  6. Seborrheic keratosis

    MedlinePlus

    ... Seborrheic kertosis. In: Lebwohl MG, Heymann WR, Berth-Jones J, Coulson I, eds. Treatment of Skin Disease: Comprehensive Therapeutic Strategies . 4th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 220. Review Date 10/24/2016 Updated by: David L. Swanson, MD, Vice Chair ...

  7. Expedition 40 crew in Node 2 after German - U.S. soccer game

    NASA Image and Video Library

    2014-06-26

    European Space Agency astronaut Alexander Gerst, Expedition 40 flight engineer, and NASA astronaut Steve Swanson, commander, gather around a computer in the Unity node of the International Space Station after the German-USA soccer match.

  8. Swans replacing filter in U.S. Laboratory

    NASA Image and Video Library

    2014-07-15

    ISS040-E-064624 (15 July 2014) --- NASA astronaut Steve Swanson, Expedition 40 commander, replaces filters in the Potable Water Dispenser (PWD) in the Destiny laboratory of the International Space Station. NASA astronaut Reid Wiseman, flight engineer, works in the background.

  9. Just add physics

    NASA Astrophysics Data System (ADS)

    Cawthorne, Trevor

    2012-04-01

    Following John Swanson's Lateral Thoughts article about uncertainty in cookery and other things (“Baking, speed limits and circuits” March p88), I would like to offer this fruit cake recipe, designed for those of us who like to know how precise our cookery should be.

  10. Systematic Interventions for Teaching Ratios

    ERIC Educational Resources Information Center

    Hunter, Amy E.; Bush, Sarah B.; Karp, Karen

    2014-01-01

    Mathematics interventions for struggling students supplement regular instruction and are frequently implemented through computer programs and activity sheet practice (Swanson et al. 2012). However, students with foundational misunderstandings do not benefit from additional drill and practice alone. Instead, interventions that balance concepts with…

  11. EVA prep

    NASA Image and Video Library

    2014-08-04

    ISS040-E-088730 (4 Aug. 2014) --- In the International Space Station?s Harmony node, NASA astronauts Steve Swanson (foreground), Expedition 40 commander; and Reid Wiseman, flight engineer, perform a portable onboard computer Dynamic Onboard Ubiquitous Graphics (DOUG) software review in preparation for two upcoming U.S. spacewalks.

  12. Science and Learning Disabilities.

    ERIC Educational Resources Information Center

    Stanovich, Keith E.

    1988-01-01

    Reactions to H. Lee Swanson's paper "Toward a Metatheory of Learning Disabilities" are outlined, and his arguments are applied to reading disabilities, focusing on the importance of the scientific attitude, the misuse of ecological validity, interpretation of Thomas Kuhn's work, modularity and reading disability, and scientific progress…

  13. KSC-07pd0494

    NASA Image and Video Library

    2007-02-22

    KENNEDY SPACE CENTER, FLA. -- In the Launch Pad 39A area, Mission STS-117 crew members receive instruction on emergency egress using the slidewire basket system during Terminal Countdown Demonstration Test activities. Here, Mission Specialists Steven Swanson (left) and Danny Olivas (right) practice exiting from the slidewire basket. The TCDT also includes M-113 armored personnel carrier training, and a simulated launch countdown. The mission payload aboard Space Shuttle Atlantis is the S3/S4 integrated truss structure, along with a third set of solar arrays and batteries. The crew of six astronauts will install the truss to continue assembly of the International Space Station. Photo credit: NASA/Kim Shiflett

  14. KSC-07pd0493

    NASA Image and Video Library

    2007-02-22

    KENNEDY SPACE CENTER, FLA. -- In the Launch Pad 39A area, Mission STS-117 crew members receive instruction on emergency egress using the slidewire basket system during Terminal Countdown Demonstration Test activities. Here, Mission Specialists Steven Swanson (left) and Danny Olivas (right) practice exiting from the slidewire basket. The TCDT also includes M-113 armored personnel carrier training, and a simulated launch countdown. The mission payload aboard Space Shuttle Atlantis is the S3/S4 integrated truss structure, along with a third set of solar arrays and batteries. The crew of six astronauts will install the truss to continue assembly of the International Space Station. Photo credit: NASA/Kim Shiflett

  15. KSC-07pd0495

    NASA Image and Video Library

    2007-02-22

    KENNEDY SPACE CENTER, FLA. -- In the Launch Pad 39A area, Mission STS-117 crew members receive instruction on emergency egress using the slidewire basket system during Terminal Countdown Demonstration Test activities. Here, Mission Specialist Steven Swanson (right) practices exiting from the slidewire basket. as Mission Specialist Danny Olivas assists. The TCDT also includes M-113 armored personnel carrier training, and a simulated launch countdown. The mission payload aboard Space Shuttle Atlantis is the S3/S4 integrated truss structure, along with a third set of solar arrays and batteries. The crew of six astronauts will install the truss to continue assembly of the International Space Station. Photo credit: NASA/Kim Shiflett

  16. STS-119 crew visit

    NASA Image and Video Library

    2009-05-05

    Stennis Space Center Director Gene Goldman (r to l) presents a commemorative photo of a space shuttle main engine test firing to STS-119 Mission Commander Lee Archambault, Pilot Tony Antonelli and Mission Specialists Steve Swanson and Richard Arnold during the crew's May 5 visit to the facility.

  17. Tools in HRD. Symposium.

    ERIC Educational Resources Information Center

    2002

    This document contains three papers from a symposium on tools in human resource development (HRD). "Game Theory Methodology in HRD" (Thomas J. Chermack, Richard A. Swanson) explores the utility of game theory in helping the HRD profession address the complexity of integrating multiple theories for disciplinary understanding and…

  18. CIR

    NASA Image and Video Library

    2014-06-11

    ISS040-E-010496 (11 June 2014) --- NASA astronaut Steve Swanson, Expedition 40 commander, works with the Multi-user Drop Combustion Apparatus (MDCA) inside the Combustion Integrated Rack (CIR) in the Destiny laboratory of the International Space Station. The MDCA contains hardware and software to conduct unique droplet combustion experiments in space.

  19. CIR

    NASA Image and Video Library

    2014-06-11

    ISS040-E-010502 (11 June 2014) --- NASA astronaut Steve Swanson, Expedition 40 commander, works with the Multi-user Drop Combustion Apparatus (MDCA) inside the Combustion Integrated Rack (CIR) in the Destiny laboratory of the International Space Station. The MDCA contains hardware and software to conduct unique droplet combustion experiments in space.

  20. Alopecia areata

    MedlinePlus

    ... Diagnosis and Therapy . 6th ed. Philadelphia, PA: Elsevier; 2016:chap 24. Vivehanantha S, Berth-Jones J. Alopecia areata. In: Lebwohl MG, Heymann WR, Berth-Jones J, Coulson I, eds. Treatment of Skin Disease: Comprehensive Therapeutic Strategies . 4th ed. Philadelphia, PA: ... Updated by: David L. Swanson, MD, Vice Chair ...

  1. Organization Structure and Strategy.

    ERIC Educational Resources Information Center

    1999

    The first of the four papers in this symposium, "Human Resource Development's Contribution to Strategic Service Quality Performance in Radisson Hotels Worldwide" (Richard A. Swanson, Julie M. Hays, Arthur V. Hill, George John, David W. Johnson, Susan Geurs), illustrates the strategic alignment and contribution of HRD (human resource…

  2. HRD & Business Outcomes.

    ERIC Educational Resources Information Center

    1996

    These four papers were presented at a symposium on human resource development (HRD) and business outcomes moderated by Barbara L. Swanson at the 1996 conference of the Academy of Human Resource Development. "Incorporating Continuous Learning into a Cultural Change Process" (Carol Ann Zulauf, Joseph A. Ilacqua), focuses on best practices at…

  3. Polymers by Non-Redox Processes: Synthesis, Physical Studies and Application

    DTIC Science & Technology

    1992-12-31

    Schiff Base," in lournal Polymer Science Polymer Chemitry , 29 749 (1991), Y. Wei, R. Hariharan and J.K. Ray. 1991-25 "Fast Atom Bombardment Mass...Graduate Student - Georgia Arbuckle Graduate Student - David Swanson Visiting Graduate Student - Angela Fagot Technician - Boris Vuchic Computer

  4. Cross-Cultural Validation of the Career Maturity Inventory: A Korean Form

    ERIC Educational Resources Information Center

    Bang, Na Mi

    2016-01-01

    As counselors become aware of the importance of providing culturally sensitive counseling, they can use evaluation and assessment to support client career development (Swanson & Fouad, 2014). For culturally sensitive career assessment, counselors should understand cultural factors, including the values and level of acculturation that may…

  5. Expedition 39 Press Conference

    NASA Image and Video Library

    2014-03-24

    Expedition 39 flight engineer Steve Swanson of NASA is seen in quarantine, behind glass, during the final press conference be Monday, March 24, 2014, at the Cosmonaut Hotel in Baikonur, Kazakhstan. The mission to the International Space Station is set to launch March 26 from the Baikonur Cosmodrome. Photo Credit: (NASA/Bill Ingalls)

  6. Expedition 39 Press Conference

    NASA Image and Video Library

    2014-03-24

    Expedition 39 flight engineer Steve Swanson of NASA is seen in quarantine, behind glass, during the final press conference be Monday, March 24, 2014, at the Cosmonaut Hotel in Baikonur, Kazakhstan. The mission to the International Space Station is set to launch March 26 from the Baikonur Cosmodrome. Photo Credit: (NASA/Joel Kowsky)

  7. 50 CFR 36.39 - Public use.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., and Swanson Lakes are only open for sport ice fishing. Andy Simons Unit Emerald Lake Green Lake Harvey... sport ice fishing. South of Sterling Highway Headquarters Lake is restricted to administrative use only..., Chickaloon (upstream of river mile 7.5), Killey, and Fox Rivers. (v) A “no-wake” restriction applies to...

  8. 50 CFR 36.39 - Public use.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., and Swanson Lakes are only open for sport ice fishing. Andy Simons Unit Emerald Lake Green Lake Harvey... sport ice fishing. South of Sterling Highway Headquarters Lake is restricted to administrative use only..., Chickaloon (upstream of river mile 7.5), Killey, and Fox Rivers. (v) A “no-wake” restriction applies to...

  9. 50 CFR 36.39 - Public use.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., and Swanson Lakes are only open for sport ice fishing. Andy Simons Unit Emerald Lake Green Lake Harvey... sport ice fishing. South of Sterling Highway Headquarters Lake is restricted to administrative use only..., Chickaloon (upstream of river mile 7.5), Killey, and Fox Rivers. (v) A “no-wake” restriction applies to...

  10. Funtionality of Sucralose/Maltodextrin: Isomalt blends in Oatmeal Cookies

    USDA-ARS?s Scientific Manuscript database

    Functionality of Sucralose/Maltodextrin:Isomalt blends in Oatmeal Cookies Ruthann B. Swanson1, Rebecca McKemie1, Elizabeth M. Savage2 and Hong Zhuang2 1University of Georgia, Athens, GA 30605; 2ARS-USDA, Athens, GA 30605 Availability of reduced-in-sugar baked products with quality characteristics...

  11. 77 FR 27508 - Self-Regulatory Organizations; New York Stock Exchange LLC; NYSE Amex LLC; Notice of Designation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-10

    ..., Themis Trading LLC, dated October 17, 2011 (``Themis Letter''); Garret Cook, dated November 4, 2011 (``Cook Letter''); James Johannes, dated November 27, 2011 (``Johannes Letter''); Ken Voorhies, dated...''); Thomas Dercks, dated December 1, 2011 (``Dercks Letter''); Eric Swanson, Secretary, BATS Global Markets...

  12. 50 CFR 36.39 - Public use.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., and Swanson Lakes are only open for sport ice fishing. Andy Simons Unit Emerald Lake Green Lake Harvey..., waysides, buildings or the Sterling Highway from the east refuge boundary to the east junction of the... buildings, piers, docks, weirs, refuge offices, visitor centers, and public access and parking sites. Maps...

  13. Spare EXT MDM Preparation

    NASA Image and Video Library

    2014-04-18

    ISS039-E-013244 (18 April 2014) --- NASA astronaut Rick Mastracchio, Expeditionn 39 flight engineer, replaces the Enhanced Input/Output Control Unit Circuit Card of the spare External Multiplexer/Demultiplexer (MDM), in preparation for an upcoming spacewalk. He will be joined by fellow NASA astronaut and Flight Engineer Steve Swanson on the spacewalk.

  14. Examining How Treatment Fidelity Is Supported, Measured, and Reported in K-3 Reading Intervention Research

    ERIC Educational Resources Information Center

    Capin, Philip; Walker, Melodee A.; Vaughn, Sharon; Wanzek, Jeanne

    2017-01-01

    Treatment fidelity data (descriptive and statistical) are critical to interpreting and generalizing outcomes of intervention research. Despite recommendations for treatment fidelity reporting from funding agencies and researchers, past syntheses have found treatment fidelity is frequently unreported (e.g., Swanson, "The Journal of Special…

  15. Measuring Self-Directed Learning: A Diagnostic Tool for Adult Learners

    ERIC Educational Resources Information Center

    Khiat, Henry

    2015-01-01

    Self-directed learning is an important form of adult learning (Caffarella, 1993; Knowles, 1975; Knowles, Holton & Swanson, 2005; Merriam, 2001; Merriam & Caffarella, 1999). The strategies of self-directed learning allow adult learners to cope better with their studies while fulfilling family, work and other commitments. This study…

  16. Culture-centered Career Intervention. [and] Diversity, Flexibility, and Career Interventions.

    ERIC Educational Resources Information Center

    Spokane, Arnold R.; Fouad, Nadya A.; Swanson, Jane L.; Walsh, W. Bruce

    2003-01-01

    Includes two commentaries on the special section. Spokane, Fouad, and Swanson emphasize the importance of two dimensions of clients' cultural context: dominant/subordinate and individual/collective. Walsh highlights research needs related to career intervention and personality, culture, process, and socioeconomic status. (Contains 15 and 11…

  17. Collaborative Strategic Reading for Students with Learning Disabilities in Upper Elementary Classrooms

    ERIC Educational Resources Information Center

    Boardman, Alison G.; Vaughn, Sharon; Buckley, Pamela; Reutebuch, Colleen; Roberts, Greg; Klingner, Janette

    2016-01-01

    Sixty fourth- and fifth-grade general education teachers were randomly assigned to teach Collaborative Strategic Reading (CSR; Klingner, Vaughn, Boardman, & Swanson, 2012), a set of reading comprehension strategies, or to a business-as-usual comparison group. Results demonstrate that students with learning disabilities (LD) who received CSR…

  18. The Future of Sport Philosophy in Higher Education Kinesiology

    ERIC Educational Resources Information Center

    Hopsicker, Peter M.; Hochstetler, Douglas

    2016-01-01

    Massengale's "Trends Toward the Future of Physical Education" (1987) makes no reference to the existence of the philosophic inquiry of physical activity within higher education kinesiology programs--even though the sub-discipline had been formalized by academics in the early 1970s. In contrast, Massengale and Swanson's "The History…

  19. Adolescent Attitudes toward Psychiatric Medication: The Utility of the Drug Attitude Inventory

    ERIC Educational Resources Information Center

    Townsend, Lisa; Floersch, Jerry; Findling, Robert L.

    2009-01-01

    Background: Despite the effectiveness of psychotropic treatment for alleviating symptoms of psychiatric disorders, youth adherence to psychotropic medication regimens is low. Adolescent adherence rates range from 10-80% (Swanson, 2003; Cromer & Tarnowski, 1989; Lloyd et al., 1998; Brown, Borden, and Clingerman, 1985; Sleator, 1985) depending on…

  20. Economics and Human Resource Development: A Rejoinder

    ERIC Educational Resources Information Center

    Wang, Greg G.; Swanson, Richard A.

    2008-01-01

    This article focuses on the areas agreement between two recent and seemingly disparate Human Resource Development Review articles by Wang and Swanson (2008) and McLean, Lynham, Azevedo, Lawrence, and Nafukho (2008). The foundational roles of economics in human resource development theory and practice are highlighted as well as the need for…

  1. KSC-07pd0491

    NASA Image and Video Library

    2007-02-22

    KENNEDY SPACE CENTER, FLA. -- In the Launch Pad 39A area, Mission STS-117 crew members receive instruction on emergency egress using the slidewire basket system during Terminal Countdown Demonstration Test activities. From left are Commander Rick Sturckow, Mission Specialist Patrick Forrester, Pilot Lee Archambault, and Mission Specialists Danny Olivas, Steven Swanson and James Reilly. The TCDT also includes M-113 armored personnel carrier training, and a simulated launch countdown. The mission payload aboard Space Shuttle Atlantis is the S3/S4 integrated truss structure, along with a third set of solar arrays and batteries. The crew of six astronauts will install the truss to continue assembly of the International Space Station. Photo credit: NASA/Kim Shiflett

  2. KSC-07pd0492

    NASA Image and Video Library

    2007-02-22

    KENNEDY SPACE CENTER, FLA. -- In the Launch Pad 39A area, Mission STS-117 crew members receive instruction on emergency egress using the slidewire basket system during Terminal Countdown Demonstration Test activities. From left are Commander Rick Sturckow, Mission Specialists Patrick Forrester and Danny Olivas, Pilot Lee Archambault, and Mission Specialists James Reilly and Steven Swanson. The TCDT also includes M-113 armored personnel carrier training, and a simulated launch countdown. The mission payload aboard Space Shuttle Atlantis is the S3/S4 integrated truss structure, along with a third set of solar arrays and batteries. The crew of six astronauts will install the truss to continue assembly of the International Space Station. Photo credit: NASA/Kim Shiflett

  3. Emotional Symptoms in Inattentive Primary School Children: A Population-Based Study

    ERIC Educational Resources Information Center

    Sorensen, Lin; Hugdahl, Kenneth; Lundervold, Astri Johansen

    2008-01-01

    Objective: The present study investigates teacher and parent reports of inattention and emotional symptoms in 6,229 primary school children. Method: The assessment included the Emotional Symptoms subscale and the Impact scale from the Strengths and Difficulties Questionnaire and the inattention items from the Swanson, Nolan, and Pelham IV…

  4. Natural Attenuation of Chlorinated Solvent Ground-Water Plumes Discharging into Wetlands

    DTIC Science & Technology

    2003-09-01

    ground water in highly saline wetlands (Swanson et al., 1984), and the distribution of marsh marigold (Caltha palustris L.) has been used to map...seeps and springs next to a lake and in wetlands in Minnesota (Rosenberry et al., 2000). Marsh marigold favors ground-water discharge areas across the

  5. Elements and Principles of Training as a Performance Improvement Solution

    ERIC Educational Resources Information Center

    Tek Aik, Chong; Tway, Duane C.

    2006-01-01

    Andragogy is the art and science of adult education that focuses on real-life application and problem-solving capacity (Knowles, Holton, & Swanson, 1998). This approach emphasizes that training effectiveness is enhanced through trainees' actual performance of the task. Workers learn better when they perceive that learning will help them perform…

  6. ASTD Technical and Skills Training Handbook.

    ERIC Educational Resources Information Center

    Kelly, Leslie, Ed.

    This handbook is intended to serve as a hands-on reference for technical trainers, many of whom are resident experts in corporations who have been recruited from within the organization rather than individuals with training background. It contains 23 chapters by experts in the field: (1) The History of Technical Training (Richard A. Swanson and…

  7. 40 CFR 147.102 - Aquifer exemptions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... than the indicated depths below the ground surface, and described by a 1/4 mile area beyond and lying directly below the following oil and gas producing fields: (i) Swanson River Field—1700 feet. (ii) Beaver Creek Field—1650 feet. (iii) Kenai Gas Field—1300 feet. (2) The portion of aquifers beneath Cook Inlet...

  8. 40 CFR 147.102 - Aquifer exemptions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... than the indicated depths below the ground surface, and described by a 1/4 mile area beyond and lying directly below the following oil and gas producing fields: (i) Swanson River Field—1700 feet. (ii) Beaver Creek Field—1650 feet. (iii) Kenai Gas Field—1300 feet. (2) The portion of aquifers beneath Cook Inlet...

  9. 40 CFR 147.102 - Aquifer exemptions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... than the indicated depths below the ground surface, and described by a 1/4 mile area beyond and lying directly below the following oil and gas producing fields: (i) Swanson River Field—1700 feet. (ii) Beaver Creek Field—1650 feet. (iii) Kenai Gas Field—1300 feet. (2) The portion of aquifers beneath Cook Inlet...

  10. 40 CFR 147.102 - Aquifer exemptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... than the indicated depths below the ground surface, and described by a 1/4 mile area beyond and lying directly below the following oil and gas producing fields: (i) Swanson River Field—1700 feet. (ii) Beaver Creek Field—1650 feet. (iii) Kenai Gas Field—1300 feet. (2) The portion of aquifers beneath Cook Inlet...

  11. Reduced-in-sugar Chocolate Chip Cookies: Functionality of Sucralose/Maltodextrin: Isomalt Blends

    USDA-ARS?s Scientific Manuscript database

    Reduced-in-sugar Chocolate Chip Cookies: Functionality of Sucralose/Maltodextrin:Isomalt Blends Rebecca McKemie1, Ruthann B. Swanson1, Elizabeth M. Savage2 and Hong Zhuang2 1University of Georgia, Athens, GA 30605; 2ARS-USDA, Athens, GA 30605 Modified baked product availability may reduce simple ...

  12. A View from the Aisle Revisited: Delight and Outrage in the Classroom

    ERIC Educational Resources Information Center

    Swanson, Scott R.; Azab, Carol; Davis, J. Charlene

    2015-01-01

    This research explores marketing students' emotional reactions to classroom encounters. We identify what types of critical incidents lead to specific emotional outcomes. The study included a sample of 1,208 marketing undergraduates. Findings confirm the viability of the taxonomies identified by Swanson and Davis (2000). We expand their framework…

  13. Reading Instruction for Students with Learning Disabilities: An Observation Study Synthesis (1980-2014)

    ERIC Educational Resources Information Center

    Walker, Melodee A.; Stevens, Elizabeth A.

    2017-01-01

    This article synthesizes observation studies investigating reading instruction for students with learning disabilities (LD) in Grades K-12. A systematic search of the literature between 1980 and 2014 resulted in the identification of 25 studies. In addition to replicating and extending E. A. Swanson's synthesis, the research questions of studies…

  14. A new rainbow trout (Oncorhynchus mykiss) reference genome assembly

    USDA-ARS?s Scientific Manuscript database

    In an effort to improve the rainbow trout reference genome assembly, we have re-sequenced the doubled-haploid Swanson line using the longest available reads from the Illumina technology. Overall we generated over 510 million 260nt paired-end shotgun reads, and 1 billion 160nt mate-pair reads from f...

  15. Innovative Session 7. [Concurrent Innovative Session at AHRD Annual Conference, 2000.

    ERIC Educational Resources Information Center

    2000

    This document consists of two papers on theory building from a conference on human resource development (HRD). Both "Theory Building Research in HRD--Pushing the Envelope!" (Richard A. Swanson, Susan A. Lynham, Wendy E. A. Ruona, Richard J. Torraco) and "The Role of Theory Building in Maturing the Human Resource Development…

  16. Messy world: managing dynamic landscape.

    Treesearch

    Sally Duncan

    1999-01-01

    What lessons does historical disturbance hold for the management of future landscapes? Fred Swanson, a researcher at the Pacific Northwest Research Station and John Cissel, research liaison for the Willamette NF, are members of a team of scientists and land managers who are examining the way we think about and manage landscapes.The team found that past...

  17. Quality Counts 2008: Tapping into Teaching--Unlocking the Key to Student Success

    ERIC Educational Resources Information Center

    Education Week, 2008

    2008-01-01

    "Quality Counts 2008" reintroduces state grades in six key areas, from the Chance-for-Success Index to the teaching profession. This special issue of "Education Week" includes the following articles: (1) Human Resources a Weak Spot (Lynn Olson); (2) Teacher Salaries, Looking at Comparable Jobs (Christopher B. Swanson); (3) Data…

  18. Component Theories for Human Resource Development in China: A Proposition

    ERIC Educational Resources Information Center

    Schmidtke, Carsten; Chen, Peng

    2016-01-01

    Chinese scholars have not yet achieved consensus on the specific theories that should be part of a Chinese HRD theory base. A review of the Chinese HRD literature has identified four theory domains frequently mentioned as a possible foundation for the discipline: management, economics, sociology, and psychology/learning. Considering Swanson and…

  19. Dialogue with an OPAC: How Visionary Was Swanson in 1964?

    ERIC Educational Resources Information Center

    Su, Shiao-Feng

    1994-01-01

    Traces the development of online public access catalogs (OPACs) and compares what has occurred with a 1964 article that outlined recommendations for a future card catalog. Subject access is emphasized, including Library of Congress Subject Headings, expansion of OPACs, user-friendly interfaces, new technologies, and current visions of the future…

  20. 76 FR 58031 - Notice of Intent To Repatriate Cultural Items: Thomas Burke Memorial Washington State Museum...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-19

    ... items were found in connection with the human remains. The cultural items are consistent with cultural.... History and Description of the Cultural Items In 1953-1954, human remains were removed from the Cedar Cave.... Earl Swanson, Jr. The human remains and objects were transferred from the University of Washington...

  1. The Functions of Reflection in High-Stakes Assessment of World Language Teacher Candidates

    ERIC Educational Resources Information Center

    Troyan, Francis J.; Kaplan, Carolyn Shemwell

    2015-01-01

    In response to the call for improving teacher candidates' familiarity with the assessment tasks and format of the edTPA (Hildebrandt & Swanson, 2014), this single case study investigated the reflective writing development of Jena, a K-12 Spanish teacher candidate, and her evolution in a pedagogy that focused on the development of writing two…

  2. A New and Improved Rainbow Trout (Oncorhynchus mykiss) Reference Genome Assembly

    USDA-ARS?s Scientific Manuscript database

    In an effort to improve the rainbow trout reference genome assembly, we re-sequenced the doubled-haploid Swanson line using the longest available reads from the Illumina technology; generating over 510 million paired-end shotgun reads (2x260nt), and 1 billion mate-pair reads (2x160nt) from four sequ...

  3. Agricultural Extension Agents' Perceptions of Effective Teaching Strategies for Adult Learners in the Master Beef Producer Program

    ERIC Educational Resources Information Center

    Strong, Robert; Harder, Amy; Carter, Hannah

    2010-01-01

    The purpose of the study reported here was to explore and describe how Extension agents selected teaching strategies for adult audiences. Andragogy is hypotheses concerning the attributes of adult learners (Knowles, Swanson, & Holton III, 2005). Extension agents responsible for teaching the Master Beef Producer (MBP) program were purposively…

  4. Transitioning from Elementary School to Middle School: The Ecology of Black Males' Behavior

    ERIC Educational Resources Information Center

    Mundy, Alma Christienne

    2014-01-01

    The purpose of this mixed method study is to explain the ecology Black males experience as they transition from elementary school to middle school in terms of behavior. The Black male graduation rate is well below 50% nationally (Orfield, Losen, Wald, & Swanson, 2004; Schott Foundation for Public Education, 2010). Graduating from high school…

  5. Successful Researcher-Practitioner RCT Partnership: Increasing Attendance by 15,000 Days

    ERIC Educational Resources Information Center

    Rogers, Todd; Wolford, Tonya; Reitano, Adrienne; Feller, Avi; Subramanyam, Shruthi; Ternovski, John

    2016-01-01

    While the adjusted cohort graduation rate of students in the United States has reached 80 percent during the 2011-12 school year (Stetser & Stillwell, 2014), in the School District of Philadelphia (SDP) only 57% of its students graduate from high school in four years, which is typical of large urban school districts (Swanson, 2009). Moreover,…

  6. Expedition 39 Press Conference

    NASA Image and Video Library

    2014-03-24

    Expedition 39 flight engineer Steve Swanson of NASA and Soyuz commander Aleksander Skvortsov of the Russian Federal Space Agency, Roscosmos are seen in quarantine, behind glass, during the final press conference be Monday, March 24, 2014, at the Cosmonaut Hotel in Baikonur, Kazakhstan. The mission to the International Space Station is set to launch March 26 from the Baikonur Cosmodrome. Photo Credit: (NASA/Joel Kowsky)

  7. Discussing Smart Pills versus Endorsing Smart Pills: Reply to Swanson, Wigal, and Volkow (2011) and Elliott and Elliott (2011)

    ERIC Educational Resources Information Center

    Farah, Martha J.; Smith, M. Elizabeth

    2011-01-01

    We find much of interest, and little to disagree with, in the commentaries on our article. We take issue only with the suggestion that our article was provocative and submit that the attempt to understand the use of stimulants as smart pills does not imply an endorsement of the practice.

  8. OH Vision Test

    NASA Image and Video Library

    2014-06-03

    ISS040-E-006739 (3 June 2014) --- European Space Agency astronaut Alexander Gerst, Expedition 40 flight engineer, uses the Optical Coherence Tomography (OCT) camera during an Ocular Health (OH) vision test in the Harmony node of the International Space Station. The OH experiment observes and seeks to understand vision changes during long-term space missions. NASA astronaut Steve Swanson (left), Expedition 40 commander, assists Gerst.

  9. Clinical Investigation Program Annual Progress Report.

    DTIC Science & Technology

    1985-09-30

    027 78/114 In Vitro Effect of Minoxidil on Collagen Produc- tion by Normal and Scleroderma Fibroblasts (C) (PR...effect of minoxidil on collagen production Dy normal and scleroderma fibroblasts. Previously titled: The use of minoxidil in treating progressive...Svc: (tO) Assoc Investigators: (11) Key Words: scleroderma, minoxidil Thomas P. O’Barr PhD, DAC fibroblasts, collagen Ellen Swanson MS, DAC Don

  10. View of the Dragon Spacecraft during EVA 26

    NASA Image and Video Library

    2014-04-23

    ISS039-E-014968 (22 April 2014) --- This snapshot of the SpaceX Dragon spacecraft docked to the International Space Station was photographed by one of two spacewalking astronauts on April 22, 2014. NASA astronauts Rick Mastracchio and Steve Swanson, Expediton 39 flight engineers, replaced a failed backup computer relay box in the S0 truss on the orbital outpost.

  11. Urban Secondary School Teachers' Understanding of Themselves as Adult Learners and Their Perceptions of Their Professional Development Experiences

    ERIC Educational Resources Information Center

    Fitzgerald, Jessica M.

    2014-01-01

    This action research study was designed to elicit urban, secondary school teachers' understandings of themselves as adult learners and their perceptions of job-embedded professional development in a single, urban school district in Connecticut. The conceptual framework that guided this study was derived from Knowles, Holton, and Swanson's (2011)…

  12. Expedition 37 Press Conference

    NASA Image and Video Library

    2013-09-24

    NASA backup crewmember Steve Swanson waves hello at a press conference held at the Cosmonaut Hotel, on Tuesday, Sept. 24, 2013, in Baikonur, Kazakhstan. Launch of the Soyuz rocket is scheduled for September 26 and will send Hopkins, Soyuz Commander Oleg Kotov and Russian Flight Engineer Sergei Ryazansky on a five and a half-month mission aboard the International Space Station. Photo Credit: (NASA/Carla Cioffi)

  13. Break the Data-Bank with Monte Carlo? Statistical Problems in the Dispute between Conroy (1996) and Crinella, McCleary, and Swanson (1998).

    ERIC Educational Resources Information Center

    Heifetz, Louis J.

    1998-01-01

    Comments on "The Small ICF/MR Program: Dimensions of Quality and Cost" (Conroy), that found small Intermediate Care Facilities (ICF) for individuals with mental retardation are inferior to other community programs. Acknowledges that while some research problems exist, no important evidence against the findings has been provided. (CR)

  14. 75 FR 51159 - B. Robert DeMento, Jr., and Baggio Herman DeMento-Continuance in Control Exemption-BDB Company...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-18

    ... Transfer, L.P.--Lease and Operation Exemption--BDB Company, in which SRT seeks Board approval to acquire..., Jr., and Baggio Herman DeMento--Continuance in Control Exemption--BDB Company and Swanson Rail Transfer, L.P. B. Robert DeMento, Jr., and Baggio Herman DeMento (DeMento Brothers), noncarrier partners...

  15. Do students with dyslexia have a different personality profile as measured with the big five?

    PubMed

    Tops, Wim; Verguts, Ellen; Callens, Maaike; Brysbaert, Marc

    2013-01-01

    Few studies are available about the personality profile of higher education students with dyslexia and to which extent this could be any different from their non-dyslexic peers. AIMS AND SAMPLES: To obtain empirical evidence, we compared the personality profile of a group of 100 Dutch-speaking students with dyslexia with that of a control group of 100 students without learning disabilities. The NEO-PI-R based on the Big Five in personality research was used. Our study showed no differences in the personality between both groups. This agrees with a recent meta-analysis of English findings (Swanson & Hsieh, 2009), suggesting that students with dyslexia do not perceive themselves differently than their non-dyslexic peers. Practical implications and directions for future research are considered.

  16. M-theory through the looking glass: Tachyon condensation in the E8 heterotic string

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Horava, Petr; Horava, Petr; Keeler, Cynthia A.

    2007-09-20

    We study the spacetime decay to nothing in string theory and M-theory. First we recall a nonsupersymmetric version of heterotic M-theory, in which bubbles of nothing -- connecting the two E_8 boundaries by a throat -- are expected to be nucleated. We argue that the fate of this system should be addressed at weak string coupling, where the nonperturbative instanton instability is expected to turn into a perturbative tachyonic one. We identify the unique string theory that could describe this process: The heterotic model with one E_8 gauge group and a singlet tachyon. We then use worldsheet methods to studymore » the tachyon condensation in the NSR formulation of this model, and show that it induces a worldsheet super-Higgs effect. The main theme of our analysis is the possibility of making meaningful alternative gauge choices for worldsheet supersymmetry, in place of the conventional superconformal gauge. We show in a version of unitary gauge how the worldsheet gravitino assimilates the goldstino and becomes dynamical. This picture clarifies recent results of Hellerman and Swanson. We also present analogs of R_\\xi gauges, and note the importance of logarithmic CFT in the context of tachyon condensation.« less

  17. Denver airport pumping systems achieve optimal [Delta] T's

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mannion, G.F.; Krist, G.D.

    1994-07-01

    This article describes how the pumping and generating systems at the new Denver Airport operate efficiently with the user loops in the buildings producing design temperature rise at all load levels. Fifteen miles east of Denver's Stapleton International Airport lies the newly completed Denver International Airport (DIA)--the world's largest and most high-tech airport. Besides being one of the largest construction projects in the works, it has many of the latest technical innovations available. Of particular interest to the HVAC industry is the design of the heating and cooling water systems. These systems provide environmental cooling and heating water to themore » three concourses, the airport office building, and the main terminal. The mechanical engineers for the project were all from the Denver area. The central plant design was the work of Behrent Engineering Co.; the three concourses were designed by Swanson-Rink Associates; and the main terminal and administrative office building were designed by Abeyta Engineering Consultants. The overall system concept was developed during the initial design phase by engineers from these firms, members of the DIA staff, and application engineers from several manufacturers.« less

  18. Inattention, Hyperactivity, and Oppositional-Defiant Symptoms in Brazilian Adolescents: Gender Prevalence and Agreement between Teachers and Parents in a Non-English Speaking Population

    ERIC Educational Resources Information Center

    Serra-Pinheiro, Maria Antonia; Mattos, Paulo; Regalla, Maria Angelica

    2008-01-01

    Objective: To assess hyperactivity (H/I), inattention (IN), and oppositional-defiant (OP) symptoms in a nonclinical Brazilian sample of adolescents, and to investigate the association between scoring profiles of teachers and parents, symptom levels, and gender. Method: Symptoms were assessed through the Swanson, Nolan, and Pelhman (SNAP-IV)…

  19. Parent and Teacher SNAP-IV Ratings of Attention Deficit Hyperactivity Disorder Symptoms: Psychometric Properties and Normative Ratings from a School District Sample

    ERIC Educational Resources Information Center

    Bussing, Regina; Fernandez, Melanie; Harwood, Michelle; Hou, Wei; Garvan, Cynthia Wilson; Eyberg, Sheila M.; Swanson, James M.

    2008-01-01

    To examine Swanson, Nolan, and Pelham-IV (SNAP-IV) psychometric properties, parent (N = 1,613) and teacher (N = 1,205) data were collected from a random elementary school student sample in a longitudinal attention deficit hyperactivity disorder (ADHD) detection study. SNAP-IV reliability was acceptable. Factor structure indicated two ADHD factors…

  20. Expedition 39 Press Conference

    NASA Image and Video Library

    2014-03-24

    Expedition 39 flight engineer Steve Swanson of NASA, Soyuz commander Aleksander Skvortsov of the Russian Federal Space Agency, Roscosmos, and flight engineer Oleg Artemyev of Roscosmos are seen in quarantine, behind glass, during the final press conference be Monday, March 24, 2014, at the Cosmonaut Hotel in Baikonur, Kazakhstan. The mission to the International Space Station is set to launch March 26 from the Baikonur Cosmodrome. Photo Credit: (NASA/Joel Kowsky)

  1. Career Education: Papers Presented at the 1972 Annual Meeting of the American Educational Research Association (Chicago, Illinois, April 4, 1972).

    ERIC Educational Resources Information Center

    American Educational Research Association, Washington, DC.

    Three of the papers in this collection present the separate models--school based, employer based, and home-community based. Titles of the five papers are: (1) "Facts and Fantasies of Career Education" by Gorden I. Swanson, (2) "Strategies for Implementing Career Education: A School Based Model" by Aaron J. Miller, (3)…

  2. Seismic Observation of Infrasonic Signals

    DTIC Science & Technology

    1984-11-01

    The implication of these results is that an infra - sonic monitoring capability already exists in the current seismic network and... infra - sonic signal recorded by the microbarographs. This arrival is linearly polarized, with a near-vertical orientation of the state vector. The...TECHNICAL REPORT NO. 84-7 cn "^ SEISMIC OBSERVATION p INFRASONIC SIGNALS D < FINAL REPORT by JACK C. SWANSON and J. CRAIG WOERPEL The views and

  3. STS-EVA Mass Ops training of the STS-117 EVA crewmembers

    NASA Image and Video Library

    2006-11-01

    JSC2006-E-47612 (1 Nov. 2006) --- Astronaut Steven R. Swanson, STS-117 mission specialist, uses the virtual reality lab at Johnson Space Center to train for his duties aboard the space shuttle and space station. This type of computer interface, paired with virtual reality training hardware and software, helps to prepare the entire team for dealing with space station elements.

  4. An Examination of Reading and Discipline Data for Elementary and Secondary African American Students: Implications for Special Education

    ERIC Educational Resources Information Center

    Bowman-Perrott, Lisa; Lewis, Chance W.

    2008-01-01

    The achievement gap between African American students and their Caucasian peers has been of concern for quite some time in the field of education (Orfield, Losen, Wald, & Swanson, 2004). As a result, this article examined high stakes reading test scores for 4,135 African American students in grades 3 through 10 in a Midwestern school district.…

  5. Soyuz TMA-12M/38S Spacecraft attached to parachute

    NASA Image and Video Library

    2014-09-11

    ISS041-E-000003 (11 Sept. 2014) --- A close-up view of a computer monitor onboard the International Space Station, photographed by an Expedition 41 crew member, shows the landing of the Soyuz TMA-12M spacecraft with NASA astronaut Steve Swanson, Expedition 40 commander; Russian cosmonaut Alexander Skvortsov, Soyuz commander and flight engineer; and Russian cosmonaut Oleg Artemyev, flight engineer, onboard.

  6. Expedition 39 Launch

    NASA Image and Video Library

    2014-03-26

    This long expsoure photograph shows the flight path of the Soyuz TMA-12M rocket as it launches from the Baikonur Cosmodrome in Kazakhstan on Wednesday, March 26, 2014. The rocket is carrying Expedition 39 Soyuz Commander Alexander Skvortsov of the Russian Federal Space Agency, Roscosmos, Flight Engineer Steven Swanson of NASA, and Flight Engineer Oleg Artemyev of Roscosmos to the International Space Station. Photo Credit: (NASA/Bill Ingalls)

  7. KSC-07pd0489

    NASA Image and Video Library

    2007-02-22

    KENNEDY SPACE CENTER, FLA. -- At the 195-foot level of the fixed service structure on Launch Pad 39A, STS-117 crew members receive instruction on emergency egress during Terminal Countdown Demonstration Test activities. From left are Mission Specialist Danny Olivas, Commander Rick Sturckow, Pilot Lee Archambault, and Mission Specialists James Reilly, Steven Swanson and Patrick Forrester. They are practicing the emergency egress procedure using the slidewire basket system to get off the pad. The TCDT also includes M-113 armored personnel carrier training, and a simulated launch countdown. The mission payload aboard Space Shuttle Atlantis is the S3/S4 integrated truss structure, along with a third set of solar arrays and batteries. The crew of six astronauts will install the truss to continue assembly of the International Space Station. Photo credit: NASA/Kim Shiflett

  8. Veg-01 Plant Harvest

    NASA Image and Video Library

    2014-06-10

    Commander Steve Swanson harvests plants for the VEG-01 investigation. He is harvesting them on the Maintenance Work Area (MWA) in the Node 2/Harmony. The Veg-01 hardware validation test investigation utilizes the Veggie facility on ISS. This investigation will assess on-orbit function and performance of the Veggie,and focus on the growth and development of Outredgeous Lettuce (Lactuca sativa ) seedlings in the spaceflight environment and the effects of the spaceflight environment on composition of microbial flora on the Veggie-grown plants and the Veggie facility. Lettuce plants are harvested on-orbit, frozen at <-80oC and returned to the ground for post-flight evaluation. Microbial sampling swabs will be taken of the Veggie facility and plant material, frozen and returned to the ground for environmental microbiological examination. Rooting pillows and water sample syringes will also be returned for microbial sampling and root analysis.

  9. Expedition 39 Press Conference

    NASA Image and Video Library

    2014-03-24

    Expedition 39 primary crew flight engineer Steve Swanson of NASA, Soyuz commander Aleksander Skvortsov of the Russian Federal Space Agency, Roscosmos, flight engineer Oleg Artemyev of Roscosmos are seen in quarantine, behind glass, during the final press conference be Monday, March 24, 2014, at the Cosmonaut Hotel in Baikonur, Kazakhstan. The mission to the International Space Station is set to launch March 26 from the Baikonur Cosmodrome. Photo Credit: (NASA/Joel Kowsky)

  10. expedition 39 Press Conference

    NASA Image and Video Library

    2014-03-24

    Expedition 39 primary crew flight engineer Steve Swanson of NASA, Soyuz commander Aleksander Skvortsov of the Russian Federal Space Agency, Roscosmos, flight engineer Oleg Artemyev of Roscosmos are seen in quarantine, behind glass, during the final press conference be Monday, March 24, 2014, at the Cosmonaut Hotel in Baikonur, Kazakhstan. The mission to the International Space Station is set to launch March 26 from the Baikonur Cosmodrome. Photo Credit: (NASA/Joel Kowsky)

  11. Expedition 39 Press Conference

    NASA Image and Video Library

    2014-03-24

    Expedition 39 backup crew member Barry Wilmore of NASA is seen in quarantine, behind glass, during the final press conference held ahead of the launch of Expedition 39 prime crew members; Soyuz Commander Alexander Skvortsov of the Russian Federal Space Agency, Flight Engineer Steve Swanson of NASA, and Flight Engineer Oleg Artemyev of Roscosmos, to the International Space Station, Monday, March 24, 2014 at the Cosmonaut Hotel in Baikonur, Kazakhstan. Photo Credit: (NASA/Joel Kowsky)

  12. The crew of Space Shuttle mission STS-117 gathered in front of the shuttle Atlantis following landing at Edwards Air Force Base, California, June 22, 2007

    NASA Image and Video Library

    2007-06-22

    The crew of Space Shuttle mission STS-117 gathered in front of the shuttle Atlantis following landing at Edwards Air Force Base, California, June 22, 2007. From left to right: mission specialists Patrick Forrester and Steven Swanson, Commander Frederick Sturckow, Pilot Lee Archambault, and mission specialists John D. Olivas and James Reilly II.

  13. Conference Proceedings of NASA/DoD Controls-Structures Interaction Technology Held in San Diego, California on 29 January-2 February 1989,

    DTIC Science & Technology

    1989-08-01

    NASA Langley Research Center, Hampton, Virginia, and Wright Research Development Center, Wright-Patterson Air Force Base, Ohio, and held in San Diego...427 Shalom Fisher SPACE TRUSS ZERO GRAVITY DYNAMICS. ............................... 445 Captain Andy Swanson UNITED STATES AIR FORCE ACADEMY GET-AWAY...HOUSE EXPERIMENTS IN LARGE SPACE STRUCTURES AT THE AIR FORCE WRIGHT AERONAUTICAL LABORATORIES FLIGHT DYNAMICS LABORATORY

  14. Robert E. Lamitie Series. "Research and Action Needs in Rural School Finance," by Robert E. Lamitie, a Response by Austin D. Swanson and Stephen L. Jacobson, and Comments by David H. Monk.

    ERIC Educational Resources Information Center

    Lamitie, Robert E.; And Others

    1989-01-01

    Examines research and trends related to equitable financing of rural schools, problems common to rural school districts, and an emerging "technology of individualization" that may negate any relationship between school effectiveness and school size. Commentaries discuss the value of district consolidation without school consolidation, and…

  15. SPHERES Slosh

    NASA Image and Video Library

    2014-06-18

    ISS040-E-013914 (18 June 2014) --- In the International Space Station's Kibo laboratory, NASA astronauts Steve Swanson (left), Expedition 40 commander; and Reid Wiseman, flight engineer, conduct test runs of the SPHERES-Slosh experiment, using the soccer-ball-sized, free-flying satellites known as Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. The SPHERES-Slosh investigation uses small robotic satellites on the space station to examine how liquids move around inside containers in microgravity.

  16. SPHERES Slosh

    NASA Image and Video Library

    2014-06-18

    ISS040-E-014615 (18 June 2014) --- In the International Space Station's Kibo laboratory, NASA astronauts Steve Swanson (top), Expedition 40 commander; and Reid Wiseman, flight engineer, conduct test runs of the SPHERES-Slosh experiment, using the soccer-ball-sized, free-flying satellites known as Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. The SPHERES-Slosh investigation uses small robotic satellites on the space station to examine how liquids move around inside containers in microgravity.

  17. SPHERES Slosh

    NASA Image and Video Library

    2014-06-18

    ISS040-E-014147 (18 June 2014) --- In the International Space Station's Kibo laboratory, NASA astronauts Steve Swanson (foreground), Expedition 40 commander; and Reid Wiseman, flight engineer, conduct test runs of the SPHERES-Slosh experiment, using the soccer-ball-sized, free-flying satellites known as Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. The SPHERES-Slosh investigation uses small robotic satellites on the space station to examine how liquids move around inside containers in microgravity.

  18. SPHERES Slosh

    NASA Image and Video Library

    2014-06-18

    ISS040-E-014536 (18 June 2014) --- In the International Space Station's Kibo laboratory, NASA astronauts Steve Swanson (left), Expedition 40 commander; and Reid Wiseman, flight engineer, conduct test runs of the SPHERES-Slosh experiment, using the soccer-ball-sized, free-flying satellites known as Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. The SPHERES-Slosh investigation uses small robotic satellites on the space station to examine how liquids move around inside containers in microgravity.

  19. SPHERES Slosh

    NASA Image and Video Library

    2014-06-18

    ISS040-E-014444 (18 June 2014) --- In the International Space Station's Kibo laboratory, NASA astronauts Steve Swanson (left), Expedition 40 commander; and Reid Wiseman, flight engineer, conduct test runs of the SPHERES-Slosh experiment, using the soccer-ball-sized, free-flying satellites known as Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. The SPHERES-Slosh investigation uses small robotic satellites on the space station to examine how liquids move around inside containers in microgravity.

  20. SPHERES Slosh

    NASA Image and Video Library

    2014-06-18

    ISS040-E-015415 (18 June 2014) --- In the International Space Station's Kibo laboratory, NASA astronauts Steve Swanson, Expedition 40 commander; and Reid Wiseman (partially obscured), flight engineer, conduct test runs of the SPHERES-Slosh experiment, using the soccer-ball-sized, free-flying satellites known as Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. The SPHERES-Slosh investigation uses small robotic satellites on the space station to examine how liquids move around inside containers in microgravity.

  1. Index of NACA Technical Publications, 1915 - 1949

    DTIC Science & Technology

    1950-03-31

    in Linearized Supersonic Swanson, Robert S. and Gillis, Clarence Wing Theory. TN 1767, April 1949. L.: ’Vind-Tunnel Calibration and Cor- rection...Symmetrical Joukowski Profiles.Heaslet, Max, A.; Lomax, Harvard and Rept. 621, 1938. Spreiter, John R.: Linearized Com- pressible-Flow Theory for Sonic Flight...Rept. 624, 1938. TheApplication of Green’s Theoremto the Solution of Boundary-Value Stack, John; Lindsey, W. F. and-Littell, Problems in Linearized

  2. Supervised Learning Based Hypothesis Generation from Biomedical Literature.

    PubMed

    Sang, Shengtian; Yang, Zhihao; Li, Zongyao; Lin, Hongfei

    2015-01-01

    Nowadays, the amount of biomedical literatures is growing at an explosive speed, and there is much useful knowledge undiscovered in this literature. Researchers can form biomedical hypotheses through mining these works. In this paper, we propose a supervised learning based approach to generate hypotheses from biomedical literature. This approach splits the traditional processing of hypothesis generation with classic ABC model into AB model and BC model which are constructed with supervised learning method. Compared with the concept cooccurrence and grammar engineering-based approaches like SemRep, machine learning based models usually can achieve better performance in information extraction (IE) from texts. Then through combining the two models, the approach reconstructs the ABC model and generates biomedical hypotheses from literature. The experimental results on the three classic Swanson hypotheses show that our approach outperforms SemRep system.

  3. A Response to Recent Reanalyses of the National Reading Panel Report: Effects of Systematic Phonics Instruction Are Practically Significant

    ERIC Educational Resources Information Center

    Stuebing, Karla K.; Barth, Amy E.; Cirino, Paul T.; Francis, David J.; Fletcher, Jack M.

    2008-01-01

    The authors examine the reassessments of the National Reading Panel (NRP) report (National Institute of Child Health and Human Development, 2000) by G. Camilli, S. Vargas, and M. Yurecko (2003); G. Camilli, P. M. Wolfe, and M. L. Smith (2006); and D. D. Hammill and H. L. Swanson (2006) that disagreed with the NRP on the magnitude of the effect of…

  4. STS-119 Group Photo in Node 2 Harmony

    NASA Image and Video Library

    2009-03-24

    S119-E-007770 (24 March 2009) --- STS-119 crewmembers pose for a group photo following a joint news conference in the Harmony node of the International Space Station while Space Shuttle Discovery remains docked with the station. From the left (bottom row) are NASA astronauts Tony Antonelli, pilot; Lee Archambault, commander; and Joseph Acaba, mission specialist. From the left (top row) are astronauts Steve Swanson, Richard Arnold and John Phillips, all mission specialists.

  5. STS-119 Group Photo in Node 2 Harmony

    NASA Image and Video Library

    2009-03-24

    S119-E-007775 (24 March 2009) --- STS-119 crewmembers pose for a group photo following a joint news conference in the Harmony node of the International Space Station while Space Shuttle Discovery remains docked with the station. From the left (bottom row) are NASA astronauts Tony Antonelli, pilot; Lee Archambault, commander; and Joseph Acaba, mission specialist. From the left (top row) are astronauts Steve Swanson, Richard Arnold and John Phillips, all mission specialists.

  6. STS-119 Group Photo in Node 2 Harmony

    NASA Image and Video Library

    2009-03-24

    S119-E-007763 (24 March 2009) --- STS-119 crewmembers pose for a group photo following a joint news conference in the Harmony node of the International Space Station while Space Shuttle Discovery remains docked with the station. From the left (bottom row) are NASA astronauts Tony Antonelli, pilot; Lee Archambault, commander; and Joseph Acaba, mission specialist. From the left (top row) are astronauts Steve Swanson, Richard Arnold and John Phillips, all mission specialists.

  7. Electric Propulsion Test and Evaluation Methodologies for Plasma in the Environments of Space and Testing (EP TEMPEST)

    DTIC Science & Technology

    2016-04-14

    Swanson AEDC Path 1: Magnetized electron transport impeded across magnetic field lines; transport via electron-particle collisions Path 2*: Electron...T&E (higher pressure, metallic walls) → Impacts stability, performance, plume properties, thruster lifetime Magnetic Field Lines Plasma Plume...Development of T&E Methodologies • Current-Voltage- Magnetic Field (I-V-B) Mapping • Facility Interaction Studies • Background Pressure • Plasma Wall

  8. International Space Station (ISS)

    NASA Image and Video Library

    2007-06-13

    STS-117 astronauts and mission specialists Patrick Forrester and Steven Swanson (out of frame), participated in the second Extra Vehicular Activity (EVA) as construction resumed on the International Space Station (ISS). Among other tasks, the two removed all of the launch locks holding the 10 foot wide solar alpha rotary joint in place and began the solar array retraction. The primary mission objective was the installment of the second and third starboard truss segments (S3 and S4).

  9. Salamander colonization of Chase Lake, Stutsman County, North Dakota

    USGS Publications Warehouse

    Mushet, David M.; McLean, Kyle I.; Stockwell, Craig A.

    2013-01-01

    Salt concentrations in lakes are dynamic. In the western United States, water diversions have caused significant declines in lake levels resulting in increased salinity, placing many aquatic species at risk (Galat and Robinson 1983, Beutel et al. 2001). Severe droughts can have similar effects on salt concentrations and aquatic communities (Swanson et al. 2003). Conversely, large inputs of water can dilute salt concentrations and contribute to community shifts (Euliss et al. 2004).

  10. Science and Technology Text Mining: Cross-Disciplinary Innovation

    DTIC Science & Technology

    2003-07-14

    been published in the medical literature (Swanson, 1986). One interesting discovery was that dietary eicosapentaenoic acid (theme "a" from literature AB...literature BC). There was no mention of eicosapentaenoic acid in the Raynaud’s disease literature, but the acid was linked to the disease through the...variable "a" values (a1, a2, etc. representing characteristics such as fish oil, eicosapentaenoic acid , and others) closely linked to the specific thematic

  11. Mechanisms and Consequences of Ebolavirus-Induced Lymphocyte Apoptosis

    DTIC Science & Technology

    2010-01-01

    apoptosis. Journal of Immunology 184:327-335 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR (S) Bradfute, SB Swanson, PE...R.S.H.) and 4.10022_08_RD_B (to S.B.). Opinions, interpretations, conclusions, and recommendations are those of the authors and are not necessarily...viruses, in- cluding Lassa, Marburg, Crimean Congo hemorrhagic fever, and some Hantavirus infections. However, no studies to our knowledge have

  12. Structure-Property Relationships in Polycyanurate / Graphene Networks

    DTIC Science & Technology

    2015-12-12

    Graphene Networks 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) A. J. Guenthner, J. T. Reams, K. R. Lamison, G...Polycyanurate / Graphene Networks Andrew J. Guenthner,1 Josiah T. Reams,2 Kevin R. Lamison,2 Gregory R. Yandek,1 David D. Swanson,1 Joseph M. Mabry1...Motivation • Sequentially Prepared Graphene Types • Polycyanurate / GO Composite Preparation • Composite Morphology • Composite Mechanical and Physical

  13. Effect of Reproductive History on Mammary Epithelial Biology

    DTIC Science & Technology

    2001-05-01

    1979 #719; Russo, 1982 #1182; Thordarson , 1995 #1748; Swanson, 1995 #1739; (17-19)]. To date, however, little evidence exists to support of any of...American Journal of Epidemiology 126, 831- 41. 16. Vatten, L. J. & Kvinnsland, S. (1992) European Journal of Cancer 28A, 1148-53. 17. Thordarson , G...Van Horn, K., Guzman, R. C., Nandi, S. & Talamantes, F. (2001) Carcinogenesis 22, 1027-33. 18. Guzman, R. C., Yang, J., Rajkumar, L., Thordarson , G

  14. A Patient-Specific Anisotropic Diffusion Model for Brain Tumour Spread.

    PubMed

    Swan, Amanda; Hillen, Thomas; Bowman, John C; Murtha, Albert D

    2018-05-01

    Gliomas are primary brain tumours arising from the glial cells of the nervous system. The diffuse nature of spread, coupled with proximity to critical brain structures, makes treatment a challenge. Pathological analysis confirms that the extent of glioma spread exceeds the extent of the grossly visible mass, seen on conventional magnetic resonance imaging (MRI) scans. Gliomas show faster spread along white matter tracts than in grey matter, leading to irregular patterns of spread. We propose a mathematical model based on Diffusion Tensor Imaging, a new MRI imaging technique that offers a methodology to delineate the major white matter tracts in the brain. We apply the anisotropic diffusion model of Painter and Hillen (J Thoer Biol 323:25-39, 2013) to data from 10 patients with gliomas. Moreover, we compare the anisotropic model to the state-of-the-art Proliferation-Infiltration (PI) model of Swanson et al. (Cell Prolif 33:317-329, 2000). We find that the anisotropic model offers a slight improvement over the standard PI model. For tumours with low anisotropy, the predictions of the two models are virtually identical, but for patients whose tumours show higher anisotropy, the results differ. We also suggest using the data from the contralateral hemisphere to further improve the model fit. Finally, we discuss the potential use of this model in clinical treatment planning.

  15. M theory through the looking glass: Tachyon condensation in the E{sub 8} heterotic string

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Horava, Petr; Keeler, Cynthia A.

    2008-03-15

    We study the spacetime decay to nothing in string theory and M-theory. First we recall a nonsupersymmetric version of heterotic M-theory, in which bubbles of nothing--connecting the two E{sub 8} boundaries by a throat--are expected to be nucleated. We argue that the fate of this system should be addressed at weak string coupling, where the nonperturbative instanton instability is expected to turn into a perturbative tachyonic one. We identify the unique string theory that could describe this process: The heterotic model with one E{sub 8} gauge group and a singlet tachyon. We then use world sheet methods to study themore » tachyon condensation in the Neveu-Schwarz-Ramond formulation of this model, and show that it induces a world sheet super-Higgs effect. The main theme of our analysis is the possibility of making meaningful alternative gauge choices for world sheet supersymmetry, in place of the conventional superconformal gauge. We show in a version of unitary gauge how the world sheet gravitino assimilates the Goldstino and becomes dynamical. This picture clarifies recent results of Hellerman and Swanson. We also present analogs of R{sub {xi}} gauges, and note the importance of logarithmic conformal field theories in the context of tachyon condensation.« less

  16. Expedition 39 Press Conference

    NASA Image and Video Library

    2014-03-24

    Expedition 39 backup crew member Elena Serova of the Russian Federal Space Agency, Roscosmos, is seen in quarantine, behind glass, during the final press conference held ahead of the launch of Expedition 39 prime crew members; Soyuz Commander Alexander Skvortsov of the Russian Federal Space Agency, Flight Engineer Steve Swanson of NASA, and Flight Engineer Oleg Artemyev of Roscosmos, to the International Space Station, Monday, March 24, 2014 at the Cosmonaut Hotel in Baikonur, Kazakhstan. Photo Credit: (NASA/Bill Ingalls)

  17. Expedition 39 Press Conference

    NASA Image and Video Library

    2014-03-24

    Expedition 39 backup crew member Aleksandr Samokutyaev of the Russian Federal Space Agency, Roscosmos, is seen in quarantine, behind glass, during the final press conference held ahead of the launch of Expedition 39 prime crew members; Soyuz Commander Alexander Skvortsov of the Russian Federal Space Agency, Flight Engineer Steve Swanson of NASA, and Flight Engineer Oleg Artemyev of Roscosmos, to the International Space Station, Monday, March 24, 2014 at the Cosmonaut Hotel in Baikonur, Kazakhstan. Photo Credit: (NASA/Bill Ingalls)

  18. Expedition 39 Crewmembers Inflight Portrait

    NASA Image and Video Library

    2014-04-11

    ISS039-E-011175 (11 April 2014) --- Inside the Zvezda service module on the Earth-orbiting International Space Station, the six Expedition 39 crew members face the camera during a call with Russian President Vladimir Putin. From left to right are NASA astronauts Rick Mastracchio and Steve Swanson, both flight engineers; Commander Koichi Wakata of the Japan Aerospace Exploration Agency (JAXA), and cosmonauts Alexander Skvortsov, Mikhail Tyurin and Oleg Artemyev, all flight engineers with Russia's Federal Space Agency (Roscosmos).

  19. Expedition 39 Crewmembers Inflight Portrait

    NASA Image and Video Library

    2014-04-11

    ISS039-E-011174 (11 April 2014) --- Inside the Zvezda service module on the Earth-orbiting International Space Station, the six Expedition 39 crew members face the camera during a call with Russian President Vladimir Putin. From left to right are NASA astronauts Rick Mastracchio and Steve Swanson, both flight engineers; Commander Koichi Wakata of the Japan Aerospace Exploration Agency (JAXA), and cosmonauts Alexander Skvortsov, Mikhail Tyurin and Oleg Artemyev, all flight engineers with Russia's Federal Space Agency (Roscosmos).

  20. Coupling of Hydrologic/Hydraulic Models and Aerial Photographs Through Time, Rio Grande Near Albuquerque, New Mexico: Report Documentary 2007 Work

    DTIC Science & Technology

    2010-08-01

    Regions (UFDP); Southwest Urban Flood Damage Program (SWDP) Coupling of Hydrologic/Hydraulic Models and Aerial Photographs Through Time , Rio Grande...Through Time , Rio Grande Near Albuquerque, New Mexico: Report Documentary 2007 Benjamin Swanson, Grant Meyer, and Julie Coonrod University of New...errors. Erosion rates appear to be generally decreasing over time , but accelerated during the 2005 high flows. Initial testing of a method for

  1. jsc2014e024979

    NASA Image and Video Library

    2014-03-06

    At the Kremlin Wall in Moscow, Expedition 39/40 Flight Engineer Oleg Artemyev of Roscosmos lays flowers in a tribute to Russian space icons who are interred there as part of ceremonial activities. Artmeyev, NASA Flight Engineer Steve Swanson and Soyuz Commander Alexander Skvortsov of Roscosmos are preparing for their launch to the International Space Station from the Baikonur Cosmodrome in Kazakhstan March 26, Kazakh time, in their Soyuz TMA-12M spacecraft for a six-month mission. NASA/Stephanie Stoll

  2. The Coding of Biological Information: From Nucleotide Sequence to Protein Recognition

    NASA Astrophysics Data System (ADS)

    Štambuk, Nikola

    The paper reviews the classic results of Swanson, Dayhoff, Grantham, Blalock and Root-Bernstein, which link genetic code nucleotide patterns to the protein structure, evolution and molecular recognition. Symbolic representation of the binary addresses defining particular nucleotide and amino acid properties is discussed, with consideration of: structure and metric of the code, direct correspondence between amino acid and nucleotide information, and molecular recognition of the interacting protein motifs coded by the complementary DNA and RNA strands.

  3. KSC-07pd0108

    NASA Image and Video Library

    2006-09-13

    KENNEDY SPACE CENTER, FLA. -- STS117-S-002 -- These six astronauts take a break from traiing to pose for the STS-117 crew portrait. Scheduled to launch aboard the Space Shuttle Atlantis are (from the left) astronauts James F. Reilly II and Steven R. Swanson, mission specialists; Frederick W. (Rick) Sturckow, commander; Lee J. Archambault, pilot; Patrick G. Forrester and John D. (Danny) Olivas, mission specialists. The crew members are attired in training versions of their shuttle launch and entry suits.

  4. Inside the Sea Dragon: The Generations within the Current Peoples Liberation Army Navy Officer Corps

    DTIC Science & Technology

    2016-06-10

    strength is inadequate; he attacks when it is abundant.46 ― Sun Tzu , The Art of War Overview There are many common misconceptions about China’s...46 Sun Tzu , The Art of War, trans. Samuel B. Griffith, 26th ed. (London: Oxford University Press, 1971), 85...Press, 1997. Sun Tzu . The Art of War. Translated by Samuel B. Griffith. 26th ed. London: Oxford University Press, 1971. Swanson, Bruce. Eighth Voyage

  5. Parity-Induced Protection Against Breast Cancer

    DTIC Science & Technology

    2001-07-01

    Nandi et al., 1995; Russo and Russo, 1978; Russo et al., 1982; Russo et al., 1979; Swanson et al., 1995; Thordarson et al., 1995; Thordarson et al...1981; Russo and Russo, 1978; Russo et al., 1977; Russo et al., 1979; Sivaraman et al., 1998; Thordarson et al., 1995; Yang et al., 1999). In contrast...1969; Russo and Russo, 1980; Sinha et al., 1988; Sivaraman et al., 1998; Thordarson et al., 1995; Medina and Smith, 1999). To extend these findings, we

  6. Chemoprevention of Breast Cancer by Mimicking the Protective Effect of Early First Birth

    DTIC Science & Technology

    2010-06-01

    Endocrinol 2002;16:2034–51. 7. Thordarson G, Jin E, Guzman RC, Swanson SM, Nandi S, Talamantes F. Refractoriness to mammary tumori- genesis in parous rats...nitrosourea-induced mammary carcinomas in female Lewis rats. Carcinogenesis 1999;20:623–8. 11. Rajkumar L, Guzman RC, Yang J, Thordarson G...Guzman RC, Yang J, Rajkumar L, Thordarson G, Chen X, Nandi S. Hormonal prevention of breast cancer: mimicking the protective effect of pregnancy. Proc

  7. Learning to recognize volcanic non-eruptions

    USGS Publications Warehouse

    Poland, Michael P.

    2010-01-01

    An important goal of volcanology is to answer the questions of when, where, and how a volcano will erupt—in other words, eruption prediction. Generally, eruption predictions are based on insights from monitoring data combined with the history of the volcano. An outstanding example is the A.D. 1980–1986 lava dome growth at Mount St. Helens, Washington (United States). Recognition of a consistent pattern of precursors revealed by geophysical, geological, and geochemical monitoring enabled successful predictions of more than 12 dome-building episodes (Swanson et al., 1983). At volcanic systems that are more complex or poorly understood, probabilistic forecasts can be useful (e.g., Newhall and Hoblitt, 2002; Marzocchi and Woo, 2009). In such cases, the probabilities of different types of volcanic events are quantified, using historical accounts and geological studies of a volcano's past activity, supplemented by information from similar volcanoes elsewhere, combined with contemporary monitoring information.

  8. LiSICON-Ionic Liquid Electrolyte for Lithium Ion Battery

    DTIC Science & Technology

    2011-08-15

    Nat Mater, 9 (2010) 353-358. [3] B. Scrosati, J. Garche, Journal of Power Sources, 195 (2010) 2419-2430. [4] F. Mizuno, A. Hayashi , K. Tadanaga, M...Minami, A. Hayashi , M. Tatsumisago, Solid State Ionics, 179 (2008) 1282-1285. [7] G. Girishkumar, B. McCloskey, A.C. Luntz, S. Swanson, W. Wilcke, The...Song, K. Zaghib, K. Kinoshita, F. McLarnon, Journal of Power Sources, 97-8 (2001) 58-66. [15] S. Seki, Y. Kobayashi, H. Miyashiro, Y. Ohno , Y. Mita, N

  9. Muramyl Peptide-Enhanced Sleep: Pharmacological Optimization of Performance.

    DTIC Science & Technology

    1987-06-01

    cycle of 12 h:12 h was maintained, light from 0600 to 1800 h. Food and water were available ad libitum. At the top of the chamber, a BRS/LVE electrical...and temperture in cat. Sleep Res. 16: 150, 1987. 108. Swanson, J. Studies on gonococcus infection. xii. Colony color and opacity variants of...Methods) received infusion. The major effectof increasing Ta to 27°C was to increase duration of slow wave sleep during the entire 6-hour recording

  10. Antonelli and Wakata at hatch of Crew Lock

    NASA Image and Video Library

    2009-03-21

    S119-E-006956 (21 March 2009) --- NASA astronaut Tony Antonelli (left), STS-119 pilot; and Japan Aerospace Exploration Agency (JAXA) astronaut Koichi Wakata, Expedition 18 flight engineer, are pictured in the Quest Airlock of the International Space Station while Space Shuttle Discovery remains docked with the station. They are about to open the hatch for Steve Swanson and Joseph Acaba, mission specialists, as they return to the station’s Quest Airlock as the mission’s second session of extravehicular activity (EVA) draws to a close.

  11. An Intensive Survey of a 2,200 Acre Tract within a Proposed Maneuver Area at the Fort Benning Military Reservation, Chattahoochee County, Georgia.

    DTIC Science & Technology

    1983-01-01

    Campbell 1979 Reelfoot and Lake Isom National Wildlife Refuge: a cultural resources survey. New World Research, Report of Investigations 20. Swanson...Investigations at Flat Bayou Watershed, Jefferson County, Arkansas. Manuscript sub- mitted to Interagency Archeological Services - Atlanta 1980 Reelfoot and Lake ...Intermittent 03 Perennial ONNW Distance to 99 Not applicable-nearest Nearest Water water is stream Other than 01 spring Streams 02 natural lake 03 well SO Soil

  12. An Assessment of the Cultural Resources within the Longhorn Army Ammunition Plant, Harrison County, Texas

    DTIC Science & Technology

    1990-03-01

    and (4) an increased use of plant foods as indicated by the addition of mortars, pestles , and mealing stones (Gadus and Howard 1988:23). Diagnostic...the area was a facet of the larger cotton growing industry that dominated the Antebellum South. The region’s cotton growers were linked to the Port of...the establishment of local rail lines, the timber industry gained importance after the 1880s. A rail line had been established from Swanson’s Landing to

  13. SPHERES Slosh

    NASA Image and Video Library

    2014-06-18

    ISS040-E-014468 (18 June 2014) --- In the International Space Station's Kibo laboratory, NASA astronauts Steve Swanson (left), Expedition 40 commander; and Reid Wiseman, flight engineer, conduct test runs of the SPHERES-Slosh experiment, using the soccer-ball-sized, free-flying satellites known as Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. The SPHERES-Slosh investigation uses small robotic satellites on the space station to examine how liquids move around inside containers in microgravity. Russian cosmonaut Maxim Suraev (bottom right), flight engineer, looks on.

  14. Expedition 39 Docking

    NASA Image and Video Library

    2014-03-28

    A view of the Russian Mission Control Center in Korolev, Russia on Friday, March 28, 2014 prior to the docking of Soyuz TMA-12M. The Soyuz TMA-12M spacecraft docked to the International Space Station at 7:53 p.m. EDT bringing Expedition 39 Soyuz Commander Alexander Skvortsov of the Russian Federal Space Agency, Roscosmos, Flight Engineer Steve Swanson of NASA and Flight Engineer Oleg Artemyev of Roscosmos to the ISS for their six month stay aboard the orbiting labratory. Photo Credit: (NASA/Joel Kowsky)

  15. Veg-01 Plant Harvest

    NASA Image and Video Library

    2014-06-10

    ISS040-E-009125 (10 June 2014) --- In the International Space Station?s Harmony node, NASA astronaut Steve Swanson, Expedition 40 commander, harvests a crop of red romaine lettuce plants that were grown from seed inside the station?s Veggie facility, a low-cost plant growth chamber that uses a flat-panel light bank for plant growth and crew observation. For the Veg-01 experiment, researchers are testing and validating the Veggie hardware, and the plants will be returned to Earth to determine food safety.

  16. Veg-01 Plant Harvest

    NASA Image and Video Library

    2014-06-10

    ISS040-E-009124 (10 June 2014) --- In the International Space Station?s Harmony node, NASA astronaut Steve Swanson, Expedition 40 commander, harvests a crop of red romaine lettuce plants that were grown from seed inside the station?s Veggie facility, a low-cost plant growth chamber that uses a flat-panel light bank for plant growth and crew observation. For the Veg-01 experiment, researchers are testing and validating the Veggie hardware, and the plants will be returned to Earth to determine food safety.

  17. Veg-01 Plant Harvest

    NASA Image and Video Library

    2014-06-10

    ISS040-E-009116 (10 June 2014) --- In the International Space Station?s Harmony node, NASA astronaut Steve Swanson, Expedition 40 commander, harvests a crop of red romaine lettuce plants that were grown from seed inside the station?s Veggie facility, a low-cost plant growth chamber that uses a flat-panel light bank for plant growth and crew observation. For the Veg-01 experiment, researchers are testing and validating the Veggie hardware, and the plants will be returned to Earth to determine food safety.

  18. Molecular Targets and Synaptic Effects of Carbamates, Organophosphates, Oximes, and Pyridiniums: Implications for Prophylaxis and Therapy of Organophosphate Toxicity

    DTIC Science & Technology

    1994-03-16

    excitability in the latter studies , it does seem that block of gK by PC, is an important factor in the pathopharmacological eltfect- of PC? in causing...muscle following acute and subacute exposure to pyridostigmine. Studies on muscle contractility and cellular mechanisms. Proc. Fourth Annual Chemical...receptor-ionic chauinel complex II. Patch dlamp studies . Mol. Pharmacol. 0 25:102-112, 1984. 7. Albuquerque, E.X., Aguayo, L., Swanson, K.L., Idriss, M

  19. Investigation of Hematologic and Pathologic Response to Decompression.

    DTIC Science & Technology

    1978-05-10

    in tadpole and very young kangaroos . Am. J. Physiol. 120:59—74 , 1937. 12. D’ C’~~~’ B.G. and Swanson , H. Bubble free decompression of blood samples...1955. 24. Takeda , Y. Studies of the metabol i~~ 5 and distribution of fibrino— gen in healthy men with autologous I-labe led fibrinogen. J. Clin...this connective tissue protein. However , the metabolism of bone collagen is affected by hormonal control (l0; 3l) and vitamin influences (3 ;ll). It

  20. SPHERES Vertigo

    NASA Image and Video Library

    2014-07-25

    ISS040-E-079083 (25 July 2014) --- In the International Space Station?s Kibo laboratory, NASA astronaut Steve Swanson, Expedition 40 commander, enters data in a computer in preparation for a session with a trio of soccer-ball-sized robots known as the Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. The free-flying robots were equipped with stereoscopic goggles called the Visual Estimation and Relative Tracking for Inspection of Generic Objects, or VERTIGO, to enable the SPHERES to perform relative navigation based on a 3D model of a target object.

  1. Chemoprevention of Breast Cancer by Mimicking the Protective Effect of Early First Birth

    DTIC Science & Technology

    2009-06-01

    mammary gland. Mol Endocrinol 2002;16:2034–51. 7. Thordarson G, Jin E, Guzman RC, Swanson SM, Nandi S, Talamantes F. Refractoriness to mammary tumori... Thordarson G, Talamantes F, Nandi S. Short-term exposure to preg- nancy levels of estrogen prevents mammary carcino- genesis. Proc Natl Acad Sci U S...A 2001;98:11755–9. 12. Guzman RC, Yang J, Rajkumar L, Thordarson G, Chen X, Nandi S. Hormonal prevention of breast cancer: mimicking the protective

  2. Chemoprevention of Breast Cancer by Mimicking the Protective Effect of Early First Birth

    DTIC Science & Technology

    2007-06-01

    Mol Endocrinol 2002;16:2034–51. 7. Thordarson G, Jin E, Guzman RC, Swanson SM, Nandi S, Talamantes F. Refractoriness to mammary tumori- genesis in...methyl-N - nitrosourea-induced mammary carcinomas in female Lewis rats. Carcinogenesis 1999;20:623–8. 11. Rajkumar L, Guzman RC, Yang J, Thordarson G...11755–9. 12. Guzman RC, Yang J, Rajkumar L, Thordarson G, Chen X, Nandi S. Hormonal prevention of breast cancer: mimicking the protective effect of

  3. Chemoprevention of Breast Cancer by Mimicking the Protective Effect of Early First Birth

    DTIC Science & Technology

    2006-06-01

    and differentiation in the rodent mammary gland. Mol Endocrinol 2002;16:2034–51. 7. Thordarson G, Jin E, Guzman RC, Swanson SM, Nandi S, Talamantes F...8. 11. Rajkumar L, Guzman RC, Yang J, Thordarson G, Talamantes F, Nandi S. Short-term exposure to preg- nancy levels of estrogen prevents mammary...carcino- genesis. Proc Natl Acad Sci U S A 2001;98:11755–9. 12. Guzman RC, Yang J, Rajkumar L, Thordarson G, Chen X, Nandi S. Hormonal prevention of

  4. Chemoprevention of Breast Cancer by Mimicking the Protective Effect of Early First Birth

    DTIC Science & Technology

    2011-06-01

    Mol Endocrinol 2002;16:2034–51. 7. Thordarson G, Jin E, Guzman RC, Swanson SM, Nandi S, Talamantes F. Refractoriness to mammary tumori- genesis in...methyl-N - nitrosourea-induced mammary carcinomas in female Lewis rats. Carcinogenesis 1999;20:623–8. 11. Rajkumar L, Guzman RC, Yang J, Thordarson G...11755–9. 12. Guzman RC, Yang J, Rajkumar L, Thordarson G, Chen X, Nandi S. Hormonal prevention of breast cancer: mimicking the protective effect of

  5. KSC-2014-2896

    NASA Image and Video Library

    2014-06-11

    CAPE CANAVERAL, Fla. – Researchers review procedures for harvesting the outredgeous red lettuce leaves in the Veggie plant growth system inside the International Space Station Environmental Simulator chamber at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida. The growth chamber was used as a control unit and procedures were followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station. The chamber mimicked the temperature, relative humidity and carbon dioxide concentration of those in the Veggie unit on the space station. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth was monitored for 33 days. On June 10, at the end of the cycle, the plants were carefully harvested, frozen and stored for return to Earth by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Photo credit: NASA/Frankie Martin

  6. KSC-2014-2467

    NASA Image and Video Library

    2014-05-09

    CAPE CANAVERAL, Fla. – Researchers have activated the red, blue and green LED lights on the Veggie plant growth system inside a control chamber at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida. From left, are Jim Smodell, a technician with SGT, and Chuck Spern, lead project engineer with QinetiQ North America. The growth chamber will be used as a control unit and procedures will be followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth will be monitored for 28 days. At the end of the cycle, the plants will be carefully harvested, frozen and stored for return to Earth. Photo credit: NASA/Dimitri Gerondidakis

  7. KSC-2014-2464

    NASA Image and Video Library

    2014-05-09

    CAPE CANAVERAL, Fla. – Researchers activate the red, blue and green LED lights on the Veggie plant growth system inside a control chamber at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida. From left, are Jim Smodell, a technician with SGT, and Chuck Spern, lead project engineer, with QinetiQ North America. The growth chamber will be used as a control unit and procedures will be followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth will be monitored for 28 days. At the end of the cycle, the plants will be carefully harvested, frozen and stored for return to Earth. Photo credit: NASA/Dimitri Gerondidakis

  8. KSC-2014-2473

    NASA Image and Video Library

    2014-05-09

    CAPE CANAVERAL, Fla. – Researchers fill a water bag with ionized water for the Veggie plant growth system inside a control chamber at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida. In front is Jim Smodell, a technician with SGT. Standing behind him is Chuck Spern, lead project engineer with QinetiQ North America. The growth chamber will be used as a control unit and procedures will be followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth will be monitored for 28 days. At the end of the cycle, the plants will be carefully harvested, frozen and stored for return to Earth. Photo credit: NASA/Dimitri Gerondidakis

  9. KSC-2014-2466

    NASA Image and Video Library

    2014-05-09

    CAPE CANAVERAL, Fla. – Researchers have activated the red, blue and green LED lights on the Veggie plant growth system inside a control chamber at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida. Jim Smodell, a technician with SGT, inserts the root mat and plant pillows containing outredgeous red romaine lettuce seeds into the Veggie unit. The growth chamber will be used as a control unit and procedures will be followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth will be monitored for 28 days. At the end of the cycle, the plants will be carefully harvested, frozen and stored for return to Earth. Photo credit: NASA/Dimitri Gerondidakis

  10. KSC-2014-2468

    NASA Image and Video Library

    2014-05-09

    CAPE CANAVERAL, Fla. – Researchers have activated the red, blue and green LED lights on the Veggie plant growth system inside a control chamber at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida. In front, is Jim Smodell, a technician with SGT. Behind him is George Guerra, a quality control engineer with QinetiQ North America. The growth chamber will be used as a control unit and procedures will be followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth will be monitored for 28 days. At the end of the cycle, the plants will be carefully harvested, frozen and stored for return to Earth. Photo credit: NASA/Dimitri Gerondidakis

  11. KSC-2014-2470

    NASA Image and Video Library

    2014-05-09

    CAPE CANAVERAL, Fla. – Researchers have activated the red, blue and green LED lights on the Veggie plant growth system inside a control chamber at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida. Jim Smodell, a technician with SGT, is securing the plant pillows containing outredgeous red romaine lettuce seeds onto the root mat inside Veggie. The growth chamber will be used as a control unit and procedures will be followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth will be monitored for 28 days. At the end of the cycle, the plants will be carefully harvested, frozen and stored for return to Earth. Photo credit: NASA/Dimitri Gerondidakis

  12. KSC-2014-2463

    NASA Image and Video Library

    2014-05-09

    CAPE CANAVERAL, Fla. – Researchers prepare to activate the Veggie plant growth system inside a control chamber at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida. From left, are George Guerra, quality control engineer, and Chuck Spern, lead project engineer, both with QinetiQ North America on the Engineering Services Contract. The growth chamber will be used as a control unit and procedures will be followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth will be monitored for 28 days. At the end of the cycle, the plants will be carefully harvested, frozen and stored for return to Earth. Photo credit: NASA/Dimitri Gerondidakis

  13. KSC-2014-2469

    NASA Image and Video Library

    2014-05-09

    CAPE CANAVERAL, Fla. – Researchers acquire the ionized water for the Veggie plant growth system inside a control chamber at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida. From left, are Jim Smodell, a technician with SGT, and George Guerra, a quality control engineer with QinetiQ North America. The growth chamber will be used as a control unit and procedures will be followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth will be monitored for 28 days. At the end of the cycle, the plants will be carefully harvested, frozen and stored for return to Earth. Photo credit: NASA/Dimitri Gerondidakis

  14. KSC-2014-2471

    NASA Image and Video Library

    2014-05-09

    CAPE CANAVERAL, Fla. – Researchers have activated the red, blue and green LED lights on the Veggie plant growth system inside a control chamber at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida. Jim Smodell, a technician with SGT, is securing the plant pillows containing outredgeous red romaine lettuce seeds onto the root mat inside Veggie. The growth chamber will be used as a control unit and procedures will be followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth will be monitored for 28 days. At the end of the cycle, the plants will be carefully harvested, frozen and stored for return to Earth. Photo credit: NASA/Dimitri Gerondidakis

  15. Knowledge synthesis with maps of neural connectivity.

    PubMed

    Tallis, Marcelo; Thompson, Richard; Russ, Thomas A; Burns, Gully A P C

    2011-01-01

    This paper describes software for neuroanatomical knowledge synthesis based on neural connectivity data. This software supports a mature methodology developed since the early 1990s. Over this time, the Swanson laboratory at USC has generated an account of the neural connectivity of the sub-structures of the hypothalamus, amygdala, septum, hippocampus, and bed nucleus of the stria terminalis. This is based on neuroanatomical data maps drawn into a standard brain atlas by experts. In earlier work, we presented an application for visualizing and comparing anatomical macro connections using the Swanson third edition atlas as a framework for accurate registration. Here we describe major improvements to the NeuARt application based on the incorporation of a knowledge representation of experimental design. We also present improvements in the interface and features of the data mapping components within a unified web-application. As a step toward developing an accurate sub-regional account of neural connectivity, we provide navigational access between the data maps and a semantic representation of area-to-area connections that they support. We do so based on an approach called "Knowledge Engineering from Experimental Design" (KEfED) model that is based on experimental variables. We have extended the underlying KEfED representation of tract-tracing experiments by incorporating the definition of a neuronanatomical data map as a measurement variable in the study design. This paper describes the software design of a web-application that allows anatomical data sets to be described within a standard experimental context and thus indexed by non-spatial experimental design features.

  16. Prevalencia y tamizaje del Trastorno por Déficit de Atención con Hiperactividad en Costa Rica

    PubMed Central

    Weiss, Nicholas T.; Schuler, Jovita; Monge, Silvia; McGough, James J.; Chavira, Denise; Bagnarello, Monica; Herrera, Luis Diego; Mathews, Carol A.

    2015-01-01

    Resumen La investigación tuvo como propósito estimar la prevalencia del Trastorno por Déficit de Atención con Hiperactividad (TDAH) en Costa Rica y determinar si la versión en español del cuestionario Swanson Nolan and Pelham Scale IV (SNAP-IV) es un instrumento de tamizaje útil en una población de niños y niñas escolares costarricenses. El instrumento fue entregado a padres y maestros de 425 niños entre 5 y 13 años de edad (promedio = 8.8). Todos fueron evaluados con el instrumento Swanson, Kotkin, Agler, M-Flynn and Pelham Scale (SKAMP). Su diagnóstico fue confirmado con una entrevista clínica. La sensibilidad y la especificidad del SNAP-IV fueron evaluadas como predictores de criterios de diagnóstico según el DSM-IV. La prevalencia puntual en la muestra del TDAH fue del 5%. El tamizaje más preciso lo hizo el SNAP-IV completado por el maestro en un corte de 20%, con una sensibilidad de 96% y una especificidad de un 82%. La sensibilidad de los instrumentos completados por los padres fue más baja que aquella de los maestros. El SNAP-IV completado por las maestras con un corte aislando el 20% de los mayores puntajes categorizó correctamente a un 87% de los sujetos. PMID:22432094

  17. Re-examination of assertiveness and aggressiveness as potential moderators of verbal intentions.

    PubMed

    Swanson, S R

    1999-06-01

    This research reports the results of a replication of Swanson and McIntyre's 1998 study of assertiveness and aggressiveness as potential moderators of verbal intentions. A convenience sample of 119 women and 71 men participated. Nonassertive subjects were least likely, while Resort-to-Aggressive subjects were the most likely, to talk with acquaintances and others. Nonassertive and Assertive subjects were significantly more likely than Aggressive ones to make recommendations. Finally, men and women scored equally assertive, but men were more likely to score aggressive. The findings generally support the earlier work.

  18. Tactical Reconnaissance and Security for the Armor Battalion Commander: Is the Scout Platoon Combat Capable or Combat Ineffective?

    DTIC Science & Technology

    1990-12-27

    reconnaissance force back to a heavy ele ,._.it capable of security missions and limited 10 reconnaissance. Vletnam continued the platoon’s emphasis on...College, Fort Leavenworth, KS, 30 November 1988 (CARL Ref. AOR215860). JouroaI ~ el Bacevich, LTC A. J. "Training Scouts." Armor, September 1987, pp. 37...Swanson, Major Steven G. " Bronco Nine Speaks His Mind." MIlitaryInteigence, April-June 1990, pp. 8- 10, 12. "The Bustle Rack." Armo,; March-April 1990

  19. SPHERES Vertigo

    NASA Image and Video Library

    2014-07-25

    ISS040-E-079355 (25 July 2014) --- In the International Space Station?s Kibo laboratory, NASA astronaut Steve Swanson (foreground), Expedition 40 commander; and European Space Agency astronaut Alexander Gerst, flight engineer, conduct a session with a trio of soccer-ball-sized robots known as the Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. The free-flying robots were equipped with stereoscopic goggles called the Visual Estimation and Relative Tracking for Inspection of Generic Objects, or VERTIGO, to enable the SPHERES to perform relative navigation based on a 3D model of a target object.

  20. SPHERES Vertigo

    NASA Image and Video Library

    2014-07-25

    ISS040-E-079129 (25 July 2014) --- In the International Space Station?s Kibo laboratory, NASA astronaut Steve Swanson (left), Expedition 40 commander; and European Space Agency astronaut Alexander Gerst, flight engineer, conduct a session with a trio of soccer-ball-sized robots known as the Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. The free-flying robots were equipped with stereoscopic goggles called the Visual Estimation and Relative Tracking for Inspection of Generic Objects, or VERTIGO, to enable the SPHERES to perform relative navigation based on a 3D model of a target object.

  1. SPHERES Vertigo

    NASA Image and Video Library

    2014-07-25

    ISS040-E-079910 (25 July 2014) --- In the International Space Station?s Kibo laboratory, NASA astronaut Steve Swanson (left), Expedition 40 commander; and European Space Agency astronaut Alexander Gerst, flight engineer, conduct a session with a trio of soccer-ball-sized robots known as the Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. The free-flying robots were equipped with stereoscopic goggles called the Visual Estimation and Relative Tracking for Inspection of Generic Objects, or VERTIGO, to enable the SPHERES to perform relative navigation based on a 3D model of a target object.

  2. SPHERES Vertigo

    NASA Image and Video Library

    2014-07-25

    ISS040-E-079332 (25 July 2014) --- In the International Space Station?s Kibo laboratory, NASA astronaut Steve Swanson (foreground), Expedition 40 commander; and European Space Agency astronaut Alexander Gerst, flight engineer, conduct a session with a trio of soccer-ball-sized robots known as the Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. The free-flying robots were equipped with stereoscopic goggles called the Visual Estimation and Relative Tracking for Inspection of Generic Objects, or VERTIGO, to enable the SPHERES to perform relative navigation based on a 3D model of a target object.

  3. Chemoprevention of Breast Cancer by Mimicking the Protective Effect of Early First Birth

    DTIC Science & Technology

    2008-06-01

    growth factors, TGF-h3, and differentiation in the rodent mammary gland. Mol Endocrinol 2002;16:2034–51. 7. Thordarson G, Jin E, Guzman RC, Swanson...Carcinogenesis 1999;20:623–8. 11. Rajkumar L, Guzman RC, Yang J, Thordarson G, Talamantes F, Nandi S. Short-term exposure to preg- nancy levels of...estrogen prevents mammary carcino- genesis. Proc Natl Acad Sci U S A 2001;98:11755–9. 12. Guzman RC, Yang J, Rajkumar L, Thordarson G, Chen X, Nandi S

  4. Knowledge Synthesis with Maps of Neural Connectivity

    PubMed Central

    Tallis, Marcelo; Thompson, Richard; Russ, Thomas A.; Burns, Gully A. P. C.

    2011-01-01

    This paper describes software for neuroanatomical knowledge synthesis based on neural connectivity data. This software supports a mature methodology developed since the early 1990s. Over this time, the Swanson laboratory at USC has generated an account of the neural connectivity of the sub-structures of the hypothalamus, amygdala, septum, hippocampus, and bed nucleus of the stria terminalis. This is based on neuroanatomical data maps drawn into a standard brain atlas by experts. In earlier work, we presented an application for visualizing and comparing anatomical macro connections using the Swanson third edition atlas as a framework for accurate registration. Here we describe major improvements to the NeuARt application based on the incorporation of a knowledge representation of experimental design. We also present improvements in the interface and features of the data mapping components within a unified web-application. As a step toward developing an accurate sub-regional account of neural connectivity, we provide navigational access between the data maps and a semantic representation of area-to-area connections that they support. We do so based on an approach called “Knowledge Engineering from Experimental Design” (KEfED) model that is based on experimental variables. We have extended the underlying KEfED representation of tract-tracing experiments by incorporating the definition of a neuronanatomical data map as a measurement variable in the study design. This paper describes the software design of a web-application that allows anatomical data sets to be described within a standard experimental context and thus indexed by non-spatial experimental design features. PMID:22053155

  5. KSC-2014-2474

    NASA Image and Video Library

    2014-05-09

    CAPE CANAVERAL, Fla. – Researchers have activated the red, blue and green LED lights on the Veggie plant growth system inside a control chamber at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida. Jim Smodell, a technician with SGT, starts the water supply to the plant pillows containing outredgeous red romaine lettuce seeds inside Veggie. Behind him is George Guerra, a quality control engineer with QinetiQ North America. The growth chamber will be used as a control unit and procedures will be followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth will be monitored for 28 days. At the end of the cycle, the plants will be carefully harvested, frozen and stored for return to Earth. Photo credit: NASA/Dimitri Gerondidakis

  6. KSC-2014-2472

    NASA Image and Video Library

    2014-05-09

    CAPE CANAVERAL, Fla. – Researchers have activated the red, blue and green LED lights on the Veggie plant growth system inside a control chamber at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida. Jim Smodell, a technician with SGT, is securing the plant pillows containing outredgeous red romaine lettuce seeds onto the root mat inside Veggie. To his left, is George Guerra, a quality control engineer with QinetiQ North America. The growth chamber will be used as a control unit and procedures will be followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth will be monitored for 28 days. At the end of the cycle, the plants will be carefully harvested, frozen and stored for return to Earth. Photo credit: NASA/Dimitri Gerondidakis

  7. KSC-2014-2465

    NASA Image and Video Library

    2014-05-09

    CAPE CANAVERAL, Fla. – Researchers have activated the red, blue and green LED lights on the Veggie plant growth system inside a control chamber at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida. They are checking the plant pillows that contain outredgeous red romaine lettuce seeds. From left, are George Guerra, quality control engineer with QinetiQ North America, and Jim Smodell, a technician with SGT. The growth chamber will be used as a control unit and procedures will be followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth will be monitored for 28 days. At the end of the cycle, the plants will be carefully harvested, frozen and stored for return to Earth. Photo credit: NASA/Dimitri Gerondidakis

  8. KSC-2014-2898

    NASA Image and Video Library

    2014-06-11

    CAPE CANAVERAL, Fla. – Inside the International Space Station Environmental Simulator chamber at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida, the bellows has been removed from around the Veggie plant growth system so that the plant pillows containing the outredgeous red lettuce leaves can be removed. The growth chamber was used as a control unit and procedures were followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station. The chamber mimicked the temperature, relative humidity and carbon dioxide concentration of those in the Veggie unit on the space station. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth was monitored for 33 days. On June 10, at the end of the cycle, the plants were carefully harvested, frozen and stored for return to Earth by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Photo credit: NASA/Frankie Martin

  9. KSC-2014-2901

    NASA Image and Video Library

    2014-06-11

    CAPE CANAVERAL, Fla. – Jim Smodell, a technician with SGT, removes the plant pillows containing the outredgeous red lettuce leaves from the Veggie plant growth system inside the International Space Station Environmental Simulator chamber at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida. The growth chamber was used as a control unit and procedures were followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station. The chamber mimicked the temperature, relative humidity and carbon dioxide concentration of those in the Veggie unit on the space station. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth was monitored for 33 days. On June 10, at the end of the cycle, the plants were carefully harvested, frozen and stored for return to Earth by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Photo credit: NASA/Frankie Martin

  10. KSC-2014-2897

    NASA Image and Video Library

    2014-06-11

    CAPE CANAVERAL, Fla. – Inside the International Space Station Environmental Simulator chamber at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida, Jim Smodell, a technician with SGT, prepares to remove the bellows from the Veggie plant growth system containing the outredgeous red lettuce leaves. The growth chamber was used as a control unit and procedures were followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station. The chamber mimicked the temperature, relative humidity and carbon dioxide concentration of those in the Veggie unit on the space station. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth was monitored for 33 days. On June 10, at the end of the cycle, the plants were carefully harvested, frozen and stored for return to Earth by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Photo credit: NASA/Frankie Martin

  11. Influence of length and diameter of implants associated with distal extension removable partial dentures.

    PubMed

    Verri, Fellippo Ramos; Pellizzer, Eduardo Piza; Rocha, Eduardo Passos; Pereira, João Antônio

    2007-09-01

    The aim of this study was to evaluate the influence of the length and diameter of the implant incorporated under the saddle of a distal-extension removable partial denture, acting as support. Six hemi-mandibular models were made with the presence of left inferior cuspid and first bicuspid, with the following differences: model A, without removable partial denture; model B, removable partial denture only; model C, removable partial denture and implant of 3.75 x x mm; model D, removable partial denture and implant of 3.75 x x3 mm; model E, removable partial denture and implant of 5 x x mm; and model F, removable partial denture and implant of 5 x x3 mm. These models were designed with the aid of AutoCAD 2000 (Autodesk, Inc., San Rafael, CA) and processed for finite element analysis by ANSYS 5.4 (Swanson Analysis Systems, Houston, PA). The loads applied were 50 N vertical on each cuspid point. It was noted that the presence of the removable partial denture overloaded the supporting tooth and other structures. The introduction of the implant reduced tensions, mainly at the extremities of the edentulous edge. Both the length and diameter tended to reduce tensions as their dimensions increased. Increasing the length of the implant had a great influence on the decrease of displacement and von Mises tension values. Increasing the diameter of the implant had a great influence on the decrease of von Mises tension values, but did not influence the displacement values. According to the results of this study, it is a good choice to use the greater and larger implant possible in the association between implant and distal extension removable partial denture.

  12. KSC-2014-2475

    NASA Image and Video Library

    2014-05-09

    CAPE CANAVERAL, Fla. – The Veggie plant growth system has been activated inside a control chamber at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida. The red, blue and green LED lights have been turned on and the root mat and plant pillows containing outredgeous red romaine lettuce seeds have been inserted into the chamber. The clear bellows have been expanded and secured. Checking the system are, from left, Gioia Massa, NASA payload scientist for Veggie, Gerard Newsham, Veggie payload support specialist with Jacobs Technology, and Trent Smith, NASA project manager. The growth chamber will be used as a control unit and procedures will be followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth will be monitored for 28 days. At the end of the cycle, the plants will be carefully harvested, frozen and stored for return to Earth. Photo credit: NASA/Dimitri Gerondidakis

  13. STS-119 Extravehicular Activity (EVA) 1 Arnold in EMU

    NASA Image and Video Library

    2009-03-19

    ISS018-E-041089 (19 March 2009) --- Astronaut Richard Arnold, STS-119 mission specialist, participates in the mission's first scheduled session of extravehicular activity (EVA) as construction and maintenance continue on the International Space Station. During the six-hour, seven-minute spacewalk, Arnold and astronaut Steve Swanson (out of frame), mission specialist, connected bolts to permanently attach the S6 truss segment to S5. The spacewalkers plugged in power and data connectors to the truss, prepared a radiator to cool it, opened boxes containing the new solar arrays and deployed the Beta Gimbal Assemblies containing masts that support the solar arrays.

  14. Expedition 40 crew in Node 2 after German - U.S. soccer game

    NASA Image and Video Library

    2014-06-26

    ISS040-E-020368 (26 June 2014) --- European Space Agency astronaut Alexander Gerst, Expedition 40 flight engineer, shaves the head of NASA astronaut Steve Swanson, commander, in the Unity node of the International Space Station. Gerst used hair clippers fashioned with a vacuum device to garner freshly cut hair. A friendly World Cup Soccer-related agreement between the crew members representing the USA, and Gerst, a German citizen who represents the European Space Agency, called for the American losers of a German-USA match to have their heads shaved. The German team won the match 1-0.

  15. Expedition 40 crew in Node 2 after German - U.S. soccer game

    NASA Image and Video Library

    2014-06-26

    ISS040-E-020364 (26 June 2014) --- European Space Agency astronaut Alexander Gerst, Expedition 40 flight engineer, shaves the head of NASA astronaut Steve Swanson, commander, in the Unity node of the International Space Station. Gerst used hair clippers fashioned with a vacuum device to garner freshly cut hair. A friendly World Cup Soccer-related agreement between the crew members representing the USA, and Gerst, a German citizen who represents the European Space Agency, called for the American losers of a German-USA match to have their heads shaved. The German team won the match 1-0.

  16. International Space Station (ISS)

    NASA Image and Video Library

    2006-09-13

    These six STS 117 astronauts, assigned to launch aboard the Space Shuttle Atlantis, are (from the left) astronauts James F. Reilly II, Steven R. Swanson, mission specialists; Frederick W. (Rick) Sturckow, commander; Lee J. Archambault, pilot; and Patrick G. Forrester and John D. (Danny) Olivas, mission specialists. The crewmembers are attired in training versions of their shuttle launch and entry suits. Mission objectives include the addition of the second and third starboard truss segments (S3/S4) with Photovoltaic Radiator (PVR), the deployed third set of solar arrays. The P6 starboard solar array wing and one radiator are to be retracted.

  17. Earth Observations taken by the Expedition 39 Crew

    NASA Image and Video Library

    2014-04-22

    ISS039-E-014807 (22 April 2014) --- As the International Space Station passed over the Bering Sea on Earth Day, one of the Expedition 39 crew members aboard the orbital outpost shot this panoramic scene looking toward Russia. The Kamchatka Peninsula can be seen in the foreground. Sunglint is visible on the left side of the frame. Only two points of view from Earth orbit were better for taking in this scene than that of the crew member with the camera inside, and those belonged to the two spacewalking astronauts -- Flight Engineers Rick Mastracchio and Steve Swanson of NASA.

  18. Exploring spatial heterogeneity and resilience in northern peatlands

    NASA Astrophysics Data System (ADS)

    Malhotra, A.; Roulet, N. T.

    2011-12-01

    Northern peatlands cover only 3% of the worlds land area while storing approximately 30% of the world's soil carbon making them important players in the global and regional carbon (C) cycle (Gorham 1991). Current peatland research attempts to predict changes in peatland biogeochemistry given climate change scenarios. However, the focus is primarily on linear responses to changes rather than on self regulation properties that are present in complex systems. Studying peatlands as complex adaptive systems (CAS) is important to fully understand peatland resilience and therefore to better predict response to disturbances. Peatlands possess properties of CAS such as spatial heterogeneity (SH), localized flows, self-organizing structures and non-linearity (Belyea and Baird 2006). The broad hypothesis of our proposed research is that SH in peatlands is positively connected with ecosystem resilience. To address our broad hypothesis we propose to 1) characterize SH in peatlands (using two visible indices of microtopography [MT] and vegetation structure [VEG]), 2) quantify the auto-correlation between visible SH and biogeochemical parameters and 3) investigate short term resilience using the response of biogeochemical parameters to environmental changes. The selection of biogeochemical parameters is based on prevalent theories on the persistence of MT in peatlands and parameters are related to peat accumulation (function of decomposition and net primary production; NPP), hydrology and nutrients (Swanson and Grigal 1988, Belyea and Clymo 2001, Eppinga et al. 2009). Field measurements will be conducted in the Stordalen mire in Abisko, Sweden. This site provides a steep environmental gradient with the presence of 3 peatland types- palsa, bog and fen. Each of these peatland types have varying degrees of spatial heterogeneity, exogenous controls (related to hydrology and permafrost), and therefore hypothesized varying degrees of resilience. Measurements will include nutrients, NPP, decomposition, surface topography, vegetation distribution, hydrology and environmental parameters. Preliminary data will be presented on the auto-correlation between MT, VEG and plant tissue nutrient in bog, fen and palsa peatland subtypes in Stordalen. We hypothesize a tighter auto-correlation between SH and nutrients in the more self-regulated system (bog) vs less self-regulated systems (palsa and fen). This research aims to provide insight into peatland self-regulation as well as improve current peatland models by generating high resolution spatial data on SH and biogeochemical parameters. Belyea, LR Baird, A. (2006). Beyond "the limits to peat bog growth": Cross-scale feedback in peatland development. Ecological Monographs, 76(3), 299-322 Belyea, L R, & Clymo, R S. (2001). Feedback control of the rate of peat formation. Proceedings. Biological sciences / The Royal Society, 268(1473), 1315-21 Eppinga, M. B., Ruiter, P. C. de, Wassen, Martin J, & Rietkerk, Max. (2009). Nutrients and hydrology indicate the driving mechanisms of peatland surface patterning. The American naturalist, 173(6), 803-18 Gorham, E. (1991). Northern Peatlands : Role in the Carbon Cycle and Probable Responses to Climatic Warming. Ecological Applications, 1(2), 182-195 Swanson, D. K., & Grigal, D. F. (1988). A Simulation Model of Mire Patterning. Oikos, 53(3), 309

  19. Chaotic Mixing in Magmatic Systems: a new experiment

    NASA Astrophysics Data System (ADS)

    de Campos, C. P.; Perugini, D.; Dingwell, D. B.; Poli, G.; Ertel-Ingrisch, W.; Hess, K.

    2007-12-01

    Previous studies on magma mixing systems have evidenced that mixing processes could be controlled by chaotic dynamics. These processes are thought to be the source of fractal structures propagating within natural magmatic systems, from meter to the micrometer length scale (Perugini et al., 2006. EPSL, 234: 669-680 and references therein). We have developed a device for experimental studies of chaotic mixing dynamics in silicate melts at high temperatures (up to 1700°C). This device has been inspired by the journal bearing or eccentric cylinder geometry for viscous fluids for the study of chaotic mixing in slow flows (Swanson and Ottino, 1990. J. Fluid Mech., 213:227-249). This geometry is thought to be an ideal system for chaotic studies because a) it is experimentally accessible/feasible for silicate rheologies and b) it is subject to an analytical solution for the stream function. In the journal bearing system the flow region, is confined in the torus between the centers of the two cylinders. Their central axes are parallel but not coincident, i. e. the cylinders are eccentric. In order to generate chaos in a flow, the streamlines must be time dependent, resulting in alternating movements between the two cylinders. This means that at least one of the cylinders has alternating rotation directions. The dimension of this new experimental device follows the required main dimensionless numbers for a chaotic flow. Our first experimental goal is to characterize the mixing process in a prototypical system (haplogranite-haplobasalt)under variable mixing protocols. muenchen.de/

  20. Healthcare providers' caring: Nothing is too small for parents and children hospitalized for heart surgery.

    PubMed

    Wei, Holly; Roscigno, Cecelia I; Swanson, Kristen M

    Parents of children with congenial heart disease (CHD) face frequent healthcare encounters due to their child's care trajectory. With an emphasis on assuring caring in healthcare, it is necessary to understand parents' perceptions of healthcare providers' actions when their child undergoes heart surgery. To describe parents' perceptions of healthcare providers' actions when their child is diagnosed with CHD and undergoes heart surgery. This is a qualitative study with in-depth interviews. Parents of children with CHD were interviewed twice after surgery. We analyzed data using directed content analysis guided by Swanson Caring Theory. Findings of the study indicate that parents perceive caring when providers seek to understand them (knowing); accompany them physically and emotionally (being with); help them (doing for); support them to be the best parents they can be (enabling); and trust them to care for their child (maintaining belief). Healthcare providers play an irreplaceable role in alleviating parents' emotional toll when their child undergoes cardiac surgery. Providers' caring is an integral component in healthcare. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. The NeuARt II system: a viewing tool for neuroanatomical data based on published neuroanatomical atlases

    PubMed Central

    Burns, Gully APC; Cheng, Wei-Cheng; Thompson, Richard H; Swanson, Larry W

    2006-01-01

    Background Anatomical studies of neural circuitry describing the basic wiring diagram of the brain produce intrinsically spatial, highly complex data of great value to the neuroscience community. Published neuroanatomical atlases provide a spatial framework for these studies. We have built an informatics framework based on these atlases for the representation of neuroanatomical knowledge. This framework not only captures current methods of anatomical data acquisition and analysis, it allows these studies to be collated, compared and synthesized within a single system. Results We have developed an atlas-viewing application ('NeuARt II') in the Java language with unique functional properties. These include the ability to use copyrighted atlases as templates within which users may view, save and retrieve data-maps and annotate them with volumetric delineations. NeuARt II also permits users to view multiple levels on multiple atlases at once. Each data-map in this system is simply a stack of vector images with one image per atlas level, so any set of accurate drawings made onto a supported atlas (in vector graphics format) could be uploaded into NeuARt II. Presently the database is populated with a corpus of high-quality neuroanatomical data from the laboratory of Dr Larry Swanson (consisting 64 highly-detailed maps of PHAL tract-tracing experiments, made up of 1039 separate drawings that were published in 27 primary research publications over 17 years). Herein we take selective examples from these data to demonstrate the features of NeuArt II. Our informatics tool permits users to browse, query and compare these maps. The NeuARt II tool operates within a bioinformatics knowledge management platform (called 'NeuroScholar') either as a standalone or a plug-in application. Conclusion Anatomical localization is fundamental to neuroscientific work and atlases provide an easily-understood framework that is widely used by neuroanatomists and non-neuroanatomists alike. NeuARt II, the neuroinformatics tool presented here, provides an accurate and powerful way of representing neuroanatomical data in the context of commonly-used brain atlases for visualization, comparison and analysis. Furthermore, it provides a framework that supports the delivery and manipulation of mapped data either as a standalone system or as a component in a larger knowledge management system. PMID:17166289

  2. Influence of implant inclination associated with mandibular class I removable partial denture.

    PubMed

    de Freitas Santos, Ciandrus Moraes; Pellizzer, Eduardo Piza; Verri, Fellippo Ramos; de Moraes, Sandra Lúcia Dantas; Falcón-Antenucci, Rosse Mary

    2011-03-01

    The aim of this study was to use two-dimensional finite element method to evaluate the displacement and stress distribution transmitted by a distal extension removable partial denture (DERPD) associated with an implant placed at different inclinations (0, 5, 15, and 30 degrees) in the second molar region of the edentulous mandible ridge. Six hemimandibular models were created: model A, only with the presence of the natural tooth 33; model B, similar to model A, with the presence of a conventional DERPD replacing the missing teeth; model C, similar to the previous model, with a straight implant (0 degrees) in the distal region of the ridge, under the denture base; model D, similar to model C, with the implant angled at 5 degrees in the mesial direction; model E, similar to model C, with the implant angled at 15 degrees in the mesial direction; and model F, similar to ME, with the implant angled at 30 degrees in the mesial direction. The models were created with the use of the AutoCAD 2000 program (Autodesk, Inc, San Rafael, CA) and processed for finite element analysis by the ANSYS 8.0 program (Swanson Analysis Systems, Houston, PA). The force applied was vertical of 50 N on each cusp tip. The results showed that the introduction of the RPD overloaded the supporting structures of the RPD and that the introduction of the implant helped to relieve the stresses of the mucosa alveolar, cortical bone, and trabecular bone. The best stress distribution occurred in model D with the implant angled at 5 degrees. The use of an implant as a support decreased the displacement of alveolar mucosa for all inclinations simulated. The stress distribution transmitted by the DERPD to the supporting structures was improved by the use of straight or slightly inclined implants. According to the displacement analysis and von Mises stress, it could be expected that straight or slightly inclined implants do not represent biomechanical risks to use.

  3. Expedition 40 crew in Node 2 after German - U.S. soccer game

    NASA Image and Video Library

    2014-06-26

    ISS040-E-020361 (26 June 2014) --- NASA astronaut Steve Swanson (right), Expedition 40 commander; and European Space Agency astronaut Alexander Gerst, flight engineer, enjoy a light moment in the Unity node of the International Space Station. Gerst is holding hair clippers fashioned with a vacuum device to garner freshly cut hair. A friendly World Cup Soccer-related agreement between the crew members representing the USA, and Gerst, a German citizen who represents the European Space Agency, called for the American losers of a German-USA match to have their heads shaved. The German team won the match 1-0.

  4. The Vocational Significance of Black Identity: Cultural Formulation Approach to Career Assessment and Career Counseling

    PubMed Central

    Byars-Winston, Angela M.

    2010-01-01

    Scholarship is emerging on intervention models that purposefully attend to cultural variables throughout the career assessment and career counseling process (Swanson & Fouad, in press). One heuristic model that offers promise to advance culturally-relevant vocational practice with African Americans is the Outline for Cultural Formulation (American Psychiatric Association, 1994). This article explicates the Outline for Cultural Formulation in career assessment and career counseling with African Americans integrating the concept of cultural identity into the entire model. The article concludes with an illustration of the Outline for Cultural Formulation model with an African American career client. PMID:20495668

  5. KSC-07pd0518

    NASA Image and Video Library

    2007-02-23

    KENNEDY SPACE CENTER, FLA. -- Mission STS-117 Mission Specialist Steven Swanson checks the fit of his launch suit and helmet, part of pre-launch preparations during terminal countdown demonstration test (TCDT) activities. The mission crew is at KSC for the TCDT, which includes a simulated launch countdown. The STS-117 mission is No. 21 to the International Space Station. Mission payloads aboard Atlantis include the S3/S4 integrated truss structure, a third set of solar arrays and batteries. The crew of six astronauts will install the truss to continue assembly of the station. Launch is scheduled for no earlier than March 15. Photo credit: NASA/Kim Shiflett.

  6. KSC-2014-2900

    NASA Image and Video Library

    2014-06-11

    CAPE CANAVERAL, Fla. – From left, Jim Smodell, a technician with SGT, and George Guerra, a quality control engineer with QinetiQ North America, prepare to remove the plant pillows containing the outredgeous red lettuce leaves from the Veggie plant growth system inside the International Space Station Environmental Simulator chamber at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida. The growth chamber was used as a control unit and procedures were followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station. The chamber mimicked the temperature, relative humidity and carbon dioxide concentration of those in the Veggie unit on the space station. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth was monitored for 33 days. On June 10, at the end of the cycle, the plants were carefully harvested, frozen and stored for return to Earth by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Photo credit: NASA/Frankie Martin

  7. KSC-2014-2906

    NASA Image and Video Library

    2014-06-11

    CAPE CANAVERAL, Fla. – The plant pillows containing the outredgeous red lettuce leaves are being harvested inside the Payload Development Laboratory at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida. From left, are Jim Smodell, a technician with SGT, and George Guerra, a quality control engineer with QinetiQ North America. The plant pillows were removed from a growth chamber was used as a control unit for the Veggie plant growth system, and procedures were followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station. The chamber mimicked the temperature, relative humidity and carbon dioxide concentration of those in the Veggie unit on the space station. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth was monitored for 33 days. On June 10, at the end of the cycle, the plants were carefully harvested, frozen and stored for return to Earth by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Photo credit: NASA/Frankie Martin

  8. KSC-2014-2907

    NASA Image and Video Library

    2014-06-11

    CAPE CANAVERAL, Fla. – Jim Smodell, a technician with SGT, removes an outredgeous red lettuce leaf from a plant pillow inside the Payload Development Laboratory at the Space Station Processing Facility, or SSPF, at NASA's Kennedy Space Center in Florida. In the background is George Guerra, a quality control engineer with QinetiQ North America. The plant pillows were removed from the Veggie plant growth system inside a control chamber at the SSPF. The growth chamber was used as a control unit for Veggie and procedures were followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station. The chamber mimicked the temperature, relative humidity and carbon dioxide concentration of those in the Veggie unit on the space station. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth was monitored for 33 days. On June 10, at the end of the cycle, the plants were carefully harvested, frozen and stored for return to Earth by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Photo credit: NASA/Frankie Martin

  9. KSC-2014-2904

    NASA Image and Video Library

    2014-06-11

    CAPE CANAVERAL, Fla. – The plant pillows containing the outredgeous red lettuce leaves have been removed from the Veggie plant growth system inside a control chamber at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida. From left, are Chuck Spern, lead project engineer with QinetiQ North America on the Engineering Services Contract, Jim Smodell, a technician with SGT, and Gioia Massa, NASA payload scientist for Veggie. The growth chamber was used as a control unit for Veggie and procedures were followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station. The chamber mimicked the temperature, relative humidity and carbon dioxide concentration of those in the Veggie unit on the space station. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth was monitored for 33 days. On June 10, at the end of the cycle, the plants were carefully harvested, frozen and stored for return to Earth by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Photo credit: NASA/Frankie Martin

  10. KSC-2014-2899

    NASA Image and Video Library

    2014-06-11

    CAPE CANAVERAL, Fla. – From left, Jim Smodell, a technician with SGT, and George Guerra, a quality control engineer with QinetiQ North America, review procedures for removing the plant pillows containing the outredgeous red lettuce leaves from the Veggie plant growth system inside the International Space Station Environmental Simulator chamber at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida. The growth chamber was used as a control unit and procedures were followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station. The chamber mimicked the temperature, relative humidity and carbon dioxide concentration of those in the Veggie unit on the space station. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth was monitored for 33 days. On June 10, at the end of the cycle, the plants were carefully harvested, frozen and stored for return to Earth by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Photo credit: NASA/Frankie Martin

  11. Neurofeedback and cognitive attention training for children with attention-deficit hyperactivity disorder in schools.

    PubMed

    Steiner, Naomi J; Frenette, Elizabeth C; Rene, Kirsten M; Brennan, Robert T; Perrin, Ellen C

    2014-01-01

    To evaluate the efficacy of 2 computer attention training systems administered in school for children with attention-deficit hyperactivity disorder (ADHD). Children in second and fourth grade with a diagnosis of ADHD (n = 104) were randomly assigned to neurofeedback (NF) (n = 34), cognitive training (CT) (n = 34), or control (n = 36) conditions. A 2-point growth model assessed change from pre-post intervention on parent reports (Conners 3-Parent [Conners 3-P]; Behavior Rating Inventory of Executive Function [BRIEF] rating scale), teacher reports (Swanson, Kotkin, Agler, M-Flynn and Pelham scale [SKAMP]; Conners 3-Teacher [Conners 3-T]), and systematic classroom observations (Behavioral Observation of Students in Schools [BOSS]). Paired t tests and an analysis of covariance assessed change in medication. Children who received NF showed significant improvement compared with those in the control condition on the Conners 3-P Attention, Executive Functioning and Global Index, on all BRIEF summary indices, and on BOSS motor/verbal off-task behavior. Children who received CT showed no improvement compared to the control condition. Children in the NF condition showed significant improvements compared to those in the CT condition on Conners 3-P Executive Functioning, all BRIEF summary indices, SKAMP Attention, and Conners 3-T Inattention subscales. Stimulant medication dosage in methylphenidate equivalencies significantly increased for children in the CT (8.54 mg) and control (7.05 mg) conditions but not for those in the NF condition (0.29 mg). Neurofeedback made greater improvements in ADHD symptoms compared to both the control and CT conditions. Thus, NF is a promising attention training treatment intervention for children with ADHD.

  12. International Space Station (ISS)

    NASA Image and Video Library

    2007-06-08

    Headed toward Earth orbit and a link up with the International Space Station (ISS), the Space Shuttle Atlantis lifted off from Kennedy Space Center on June 8, 2007. Aboard were STS-117 astronauts James F. Reilly II, Steven R. Swanson, Patrick G. Forrester and John D. “Danny” Olivas, all mission specialists; Frederick W. (Rick) Sturckow, commander; Lee J. Archambault, pilot; and Clayton Anderson, mission specialist who joined the Expedition 15 crew. The crew members along with the Expedition 15 crew spent 8 days resuming construction on the ISS with the installation of the second and third starboard truss segments (S3 and S4) with Photovoltaic Radiator (PVR), and retracted the P6 starboard solar array wing and radiator for later use.

  13. jsc2013e080238

    NASA Image and Video Library

    2013-09-06

    At the Kremlin Wall at Red Square in Moscow, Five of the six Expedition 37/38 prime and backup crewmembers pose for pictures Sept. 6 during the traditional visit to lay flowers at the wall where Russian space icons are interred. With the onion domed spires of St. Basil’s Cathedral in the background, from left to right are backup NASA Flight Engineer Steve Swanson, prime Flight Engineer Michael Hopkins of NASA, prime Soyuz Commander Oleg Kotov, prime Flight Engineer Sergey Ryazanskiy and backup Flight Engineer Oleg Artemyev. Hopkins, Kotov and Ryazanskiy are preparing for their launch to the International Space Station from the Baikonur Cosmodrome in Kazakhstan on Sept. 26, Kazakh time, aboard the Soyuz TMA-10M spacecraft. NASA/Stephanie Stoll

  14. Expedition 40 crew in Node 2 after German - U.S. soccer game

    NASA Image and Video Library

    2014-06-26

    ISS040-E-020367 (26 June 2014) --- European Space Agency astronaut Alexander Gerst, Expedition 40 flight engineer, shaves the head of NASA astronaut Steve Swanson, commander, in the Unity node of the International Space Station. Gerst used hair clippers fashioned with a vacuum device to garner freshly cut hair. Russian cosmonaut Alexander Skvortsov, flight engineer, is visible in the background. A friendly World Cup Soccer-related agreement between the crew members representing the USA, and Gerst, a German citizen who represents the European Space Agency, called for the American losers of a German-USA match to have their heads shaved. The German team won the match 1-0.

  15. Cortical bone stress distribution in mandibles with different configurations restored with prefabricated bar-prosthesis protocol: a three-dimensional finite-element analysis.

    PubMed

    de Almeida, Erika Oliveira; Rocha, Eduardo Passos; Assunção, Wirley Gonçalves; Júnior, Amílcar Chagas Freitas; Anchieta, Rodolfo Bruniera

    2011-01-01

    To evaluate stress distribution in different horizontal mandibular arch formats restored by protocol-type prostheses using three-dimensional finite element analysis (3D-FEA). A representative model (M) of a completely edentulous mandible restored with a prefabricated bar using four interforaminal implants was created using SolidWorks 2010 software (Inovart, São Paulo, Brazil) and analyzed by Ansys Workbench 10.0 (Swanson Analysis Inc., Houston, PA) to obtain the stress fields. Three mandibular arch sizes were considered for analysis, regular (M), small (MS), and large (ML). Three unilateral posterior loads (L) (150 N) were used: perpendicular to the prefabricated bar (L1); 30° oblique in a buccolingual direction (L2); 30° oblique in a lingual-buccal direction (L3). The maximum and minimum principal stresses (σ(max), σ(min)), the equivalent von Mises (σ(vM)), and the maximum principal strain (σ(max) ) were obtained for type I (M.I) and type II (M.II) cortical bones. Tensile stress was more evident than compression stress in type I and II bone; however, type II bone showed lower stress values. The L2 condition showed highest values for all parameters (σ(vM), σ(max), σ(min), ɛ(max)). The σ(vM) was highest for the large and small mandibular arches. The large arch model had a higher influence on σ(max) values than did the other formats, mainly for type I bone. Vertical and buccolingual loads showed considerable influence on both σ(max) and σ(min) stresses. © 2010 by The American College of Prosthodontists.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Swanson, James

    The Dopamine (DA) Hypothesis of ADHD (Wender, 1971; Levy, 1990) suggests that abnormalities in the synaptic mechanisms of DA transmission may be disrupted, and specific abnormalities in DA receptors and DA transporters (DAT) have been proposed (see Swanson et al, 1998). Early studies with small samples (e.g., n = 6, Dougherty et al, 1999) used single photon emission tomography (SPECT) and the radioligand (123I Altropane) to test a theory that ADHD may be caused by an over expression of DAT and reported 'a 70% increase in age-corrected dopamine transporter density in patients with attention deficit hyperactivity disorder compared with healthymore » controls' and suggested that treatment with stimulant medication decreased DAT density in ADHD patients and corrected an underlying abnormality (Krause et al, 2000). The potential importance of these findings was noted by Swanson (1999): 'If true, this is a major finding and points the way for new investigations of the primary pharmacological treatment for ADHD (with the stimulant drugs - e.g., methylphenidate), for which the dopamine transporter is the primary site of action. The potential importance of this finding demands special scrutiny'. This has been provided over the past decade using Positron Emission Tomography (PET). Brain imaging studies were conducted at Brookhaven National Laboratory (BNL) in a relatively large sample of stimulant-naive adults assessed for DAT (11C cocaine) density and DA receptors (11C raclopride) availability. These studies (Volkow et al, 2007; Volkow et al, 2009) do not confirm the hypothesis of increased DAT density and suggest the opposite (i.e., decreased rather than increased DAT density), and follow-up after treatment (Wang et al, 2010) does not confirm the hypothesis that therapeutic doses of methylphenidate decrease DAT density and suggests the opposite (i.e., increased rather than decreased DAT density). The brain regions implicated by these PET imaging studies also suggest that a motivation deficit may contribute as much as an attention deficit to the manifestation of behaviors that underlie the symptoms of ADHD.« less

  17. What is Swanson's Law & why Should you Care?

    NASA Astrophysics Data System (ADS)

    Hansen, S. F.; Partain, L.; Hansen, R. T.

    2015-12-01

    For 40 years the cost of Solar Photovoltaics (PV) has decreased by a factor of 2 for every 10X increase in its cumulative-installed electric-generating capacity (CC). The straight line, log-log, experimental and historical data fit of cost versus CC is called Swanson's Law for its accurate fit of the rapid decrease in cost over 6 orders of magnitude increase in CC with time. Now Solar PV is cost competitive with coal and natural gas in some regions and provides 1% of the world's electric generating capacity. The Law can next be tested to predict the future. With 2 more orders of magnitude increase in CC, Solar PV could provide 10% and then 100% of the world's current electric capacity, as the Law projects costs falling by another factor of 4. For the last 10 years CC has doubled every 2 years under strong public policy support. If this doubling and policy support are extended, an order-of-magnitude increase (10X) will occur every 6.6 yrs and installed solar PV capacity could reach 100% of the current world's consumption in 13 years or by 2028. The world's solar resource, accessible indefinitely and yearly to PV, is over 1000 times current consumption while coal, uranium, petroleum and natural gas are finite, limited resources, destined to be depleted within our lifetimes or the lives of our children or grandchildren. In 2015 a 56 MW fossil fueled power plant was shut down at Stanford University and replaced with Solar PV and geothermal to save money and eliminate greenhouse gas emissions. If more such shut downs could follow this same 2 year doubling time as Solar PV, then the replacements could exceed 14,000 within 26 years or by 2041, including all 7000 current coal-fired plants plus an equivalent number fueled by uranium, petroleum and natural gas. These shut-downs, including all current fossil-fueled-power plants, could start reversing the human-generated, greenhouse-gas-induced, global climate changes by 2041.

  18. Evaluation of the Dopamine Hypothesis of ADHD with PET Brain Imaging

    ScienceCinema

    Swanson, James

    2018-01-24

    The Dopamine (DA) Hypothesis of ADHD (Wender, 1971; Levy, 1990) suggests that abnormalities in the synaptic mechanisms of DA transmission may be disrupted, and specific abnormalities in DA receptors and DA transporters (DAT) have been proposed (see Swanson et al, 1998). Early studies with small samples (e.g., n = 6, Dougherty et al, 1999) used single photon emission tomography (SPECT) and the radioligand (123I Altropane) to test a theory that ADHD may be caused by an over expression of DAT and reported 'a 70% increase in age-corrected dopamine transporter density in patients with attention deficit hyperactivity disorder compared with healthy controls' and suggested that treatment with stimulant medication decreased DAT density in ADHD patients and corrected an underlying abnormality (Krause et al, 2000). The potential importance of these findings was noted by Swanson (1999): 'If true, this is a major finding and points the way for new investigations of the primary pharmacological treatment for ADHD (with the stimulant drugs - e.g., methylphenidate), for which the dopamine transporter is the primary site of action. The potential importance of this finding demands special scrutiny'. This has been provided over the past decade using Positron Emission Tomography (PET). Brain imaging studies were conducted at Brookhaven National Laboratory (BNL) in a relatively large sample of stimulant-naive adults assessed for DAT (11C cocaine) density and DA receptors (11C raclopride) availability. These studies (Volkow et al, 2007; Volkow et al, 2009) do not confirm the hypothesis of increased DAT density and suggest the opposite (i.e., decreased rather than increased DAT density), and follow-up after treatment (Wang et al, 2010) does not confirm the hypothesis that therapeutic doses of methylphenidate decrease DAT density and suggests the opposite (i.e., increased rather than decreased DAT density). The brain regions implicated by these PET imaging studies also suggest that a motivation deficit may contribute as much as an attention deficit to the manifestation of behaviors that underlie the symptoms of ADHD.

  19. Psychiatric rehabilitation education for physicians.

    PubMed

    Rudnick, Abraham; Eastwood, Diane

    2013-06-01

    As part of a rapidly spreading reform toward recovery-oriented services, mental health care systems are adopting Psychiatric/Psychosocial Rehabilitation (PSR). Accordingly, PSR education and training programs are now available and accessible. Although psychiatrists and sometimes other physicians (such as family physicians) provide important services to people with serious mental illnesses and may, therefore, need knowledge and skill in PSR, it seems that the medical profession has been slow to participate in PSR education. Based on our experience working in Canada as academic psychiatrists who are also Certified Psychiatric Rehabilitation Practitioners (CPRPs), we offer descriptions of several Canadian initiatives that involve physicians in PSR education. Multiple frameworks guide PSR education for physicians. First, guidance is provided by published PSR principles, such as the importance of self-determination (www.psrrpscanada.ca). Second, guidance is provided by adult education (andragogy) principles, emphasizing the importance of addressing attitudes in addition to knowledge and skills (Knowles, Holton, & Swanson, 2011). Third, guidance in Canada is provided by Canadian Medical Education Directives for Specialists (CanMEDS) principles, which delineate the multiple roles of physicians beyond that of medical expert (Frank, 2005) and have recently been adopted in Australia (Boyce, Spratt, Davies, & McEvoy, 2011). (PsycINFO Database Record (c) 2013 APA, all rights reserved).

  20. KSC-2014-2908

    NASA Image and Video Library

    2014-06-11

    CAPE CANAVERAL, Fla. – Jim Smodell, a technician with SGT, removes an outredgeous red lettuce leaf from a plant pillow inside the Payload Development Laboratory at the Space Station Processing Facility, or SSPF, at NASA's Kennedy Space Center in Florida. The plant pillows were removed from the Veggie plant growth system inside a control chamber at the SSPF. The growth chamber was used as a control unit for Veggie and procedures were followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station. The lettuce leaves will be wrapped and placed in a minus eighty-degree freezer, along with the plant pillows and samples swabbed from the plants, plant pillows and Veggie bellows. The chamber mimicked the temperature, relative humidity and carbon dioxide concentration of those in the Veggie unit on the space station. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth was monitored for 33 days. On June 10, at the end of the cycle, the plants were carefully harvested, frozen and stored for return to Earth by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Photo credit: NASA/Frankie Martin

  1. STS-119 Extravehicular Activity (EVA) 1 Arnold in Extravehicular Mobility Unit (EMU)

    NASA Image and Video Library

    2009-03-19

    ISS018-E-041104 (19 March 2009) --- Astronaut Richard Arnold, STS-119 mission specialist, participates in the mission's first scheduled session of extravehicular activity (EVA) as construction and maintenance continue on the International Space Station. During the six-hour, seven-minute spacewalk, Arnold and astronaut Steve Swanson (out of frame), mission specialist, connected bolts to permanently attach the S6 truss segment to S5. The spacewalkers plugged in power and data connectors to the truss, prepared a radiator to cool it, opened boxes containing the new solar arrays and deployed the Beta Gimbal Assemblies containing masts that support the solar arrays. The blackness of space and Earth?s horizon provide the backdrop for the scene.

  2. STS-119 Crew Walkout

    NASA Image and Video Library

    2009-03-15

    STS119-S-008 (15 March 2009) --- After suiting up, the STS-119 crewmembers pause alongside the Astrovan to wave farewell to onlookers before heading for launch pad 39A for the launch of Space Shuttle Discovery on the STS-119 mission. From the right are astronauts Lee Archambault, commander; Tony Antonelli, pilot; Joseph Acaba, Steve Swanson, Richard Arnold, John Phillips and Japan Aerospace Exploration Agency’s Koichi Wakata, all mission specialists. Wakata will join Expedition 18 in progress to serve as a flight engineer aboard the International Space Station. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science.

  3. Prediction of breakdown strength of cellulosic insulating materials using artificial neural networks

    NASA Astrophysics Data System (ADS)

    Singh, Sakshi; Mohsin, M. M.; Masood, Aejaz

    In this research work, a few sets of experiments have been performed in high voltage laboratory on various cellulosic insulating materials like diamond-dotted paper, paper phenolic sheets, cotton phenolic sheets, leatheroid, and presspaper, to measure different electrical parameters like breakdown strength, relative permittivity, loss tangent, etc. Considering the dependency of breakdown strength on other physical parameters, different Artificial Neural Network (ANN) models are proposed for the prediction of breakdown strength. The ANN model results are compared with those obtained experimentally and also with the values already predicted from an empirical relation suggested by Swanson and Dall. The reported results indicated that the breakdown strength predicted from the ANN model is in good agreement with the experimental values.

  4. KSC-07pd0486

    NASA Image and Video Library

    2007-02-22

    KENNEDY SPACE CENTER, FLA. -- During Terminal Countdown Demonstration Test activities, the Mission STS-117 crew members receive instruction on emergency egress during a walkdown of the 195-foot level of the fixed service structure at Launch Pad 39A. From the left are Mission Specialists Steven Swanson, Danny Olivas and Patrick Forrester, Pilot Lee Archambault, Commander Rick Sturckow and Mission Specialist James Reilly. The TCDT also includes M-113 armored personnel carrier training, and a simulated launch countdown. The mission payload aboard Space Shuttle Atlantis is the S3/S4 integrated truss structure, along with a third set of solar arrays and batteries. The crew of six astronauts will install the truss to continue assembly of the International Space Station. Photo credit: NASA/Kim Shiflett

  5. Ethical issues in the qualitative researcher--participant relationship.

    PubMed

    Eide, Phyllis; Kahn, David

    2008-03-01

    Qualitative research poses ethical issues and challenges unique to the study of human beings. In developing the interpersonal relationship that is critical to qualitative research, investigator and participant engage in a dialogic process that often evokes stories and memories that are remembered and reconstituted in ways that otherwise would not occur. Ethical issues are raised when this relationship not only provides qualitative research data, but also leads to some degree of therapeutic interaction for the participant. The purpose of this article is to examine some of the controversies inherent in the researcher's dilemma when this occurs, set within the context of a nursing caring theory (Swanson), and the International Council of Nurses Code of ethics for nurses, which provides guidance on global nursing practice.

  6. Disappearing Q operator

    NASA Astrophysics Data System (ADS)

    Jones, H. F.; Rivers, R. J.

    2007-01-01

    In the Schrödinger formulation of non-Hermitian quantum theories a positive-definite metric operator η≡e-Q must be introduced in order to ensure their probabilistic interpretation. This operator also gives an equivalent Hermitian theory, by means of a similarity transformation. If, however, quantum mechanics is formulated in terms of functional integrals, we show that the Q operator makes only a subliminal appearance and is not needed for the calculation of expectation values. Instead, the relation to the Hermitian theory is encoded via the external source j(t). These points are illustrated and amplified for two non-Hermitian quantum theories: the Swanson model, a non-Hermitian transform of the simple harmonic oscillator, and the wrong-sign quartic oscillator, which has been shown to be equivalent to a conventional asymmetric quartic oscillator.

  7. Disappearing Q operator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jones, H. F.; Rivers, R. J.

    In the Schroedinger formulation of non-Hermitian quantum theories a positive-definite metric operator {eta}{identical_to}e{sup -Q} must be introduced in order to ensure their probabilistic interpretation. This operator also gives an equivalent Hermitian theory, by means of a similarity transformation. If, however, quantum mechanics is formulated in terms of functional integrals, we show that the Q operator makes only a subliminal appearance and is not needed for the calculation of expectation values. Instead, the relation to the Hermitian theory is encoded via the external source j(t). These points are illustrated and amplified for two non-Hermitian quantum theories: the Swanson model, a non-Hermitianmore » transform of the simple harmonic oscillator, and the wrong-sign quartic oscillator, which has been shown to be equivalent to a conventional asymmetric quartic oscillator.« less

  8. STS-119 Crew Walkout

    NASA Image and Video Library

    2009-03-15

    STS119-S-007 (15 March 2009) --- After suiting up, the STS-119 crewmembers exit the Operations and Checkout Building to board the Astrovan, which will take them to launch pad 39A for the launch of Space Shuttle Discovery on the STS-119 mission. From the left are astronauts John Phillips, Japan Aerospace Exploration Agency’s Koichi Wakata, Steve Swanson, Richard Arnold, all mission specialists; Tony Antonelli, pilot; Joseph Acaba (behind Antonelli), mission specialist; and Lee Archambault, commander. Wakata will join Expedition 18 in progress to serve as a flight engineer aboard the International Space Station. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science.

  9. KSC-07pd0497

    NASA Image and Video Library

    2007-02-22

    KENNEDY SPACE CENTER, FLA. -- Mission STS-117 crew members receive emergency egress instruction at Launch Pad 39A during Terminal Countdown Demonstration Test activities. From the left in front are Pilot Lee Archambault, Mission Specialists Danny Olivas and Steven Swanson, Commander Rick Sturckow and Mission Specialist Patrick Forrester. Directly behind Olivas is Mission Specialist James Reilly. At right is a partial view of the M-113 armored personnel carrier. The TCDT also includes M-113 armored personnel carrier training, and a simulated launch countdown. The mission payload aboard Space Shuttle Atlantis is the S3/S4 integrated truss structure, along with a third set of solar arrays and batteries. The crew of six astronauts will install the truss to continue assembly of the International Space Station. Photo credit: NASA/Kim Shiflett

  10. STS-119 Launch

    NASA Image and Video Library

    2009-03-15

    STS119-S-023 (15 March 2009) --- The Space Shuttle Discovery and its seven-member STS-119 crew head toward Earth orbit and a scheduled link-up with the International Space Station. Liftoff was on time at 7:43 p.m. (EDT) on March 15, 2009 from launch pad 39A at NASA’s Kennedy Space Center. Onboard are astronauts Lee Archambault, commander; Tony Antonelli, pilot; Joseph Acaba, Steve Swanson, Richard Arnold, John Phillips and Japan Aerospace Exploration Agency’s Koichi Wakata, all mission specialists. Wakata will join Expedition 18 in progress to serve as a flight engineer aboard the space station. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science.

  11. STS-119 Launch

    NASA Image and Video Library

    2009-03-15

    STS119-S-020 (15 March 2009) --- The Space Shuttle Discovery and its seven-member STS-119 crew head toward Earth orbit and a scheduled link-up with the International Space Station. Liftoff was on time at 7:43 p.m. (EDT) on March 15, 2009 from launch pad 39A at NASA’s Kennedy Space Center. Onboard are astronauts Lee Archambault, commander; Tony Antonelli, pilot; Joseph Acaba, Steve Swanson, Richard Arnold, John Phillips and Japan Aerospace Exploration Agency’s Koichi Wakata, all mission specialists. Wakata will join Expedition 18 in progress to serve as a flight engineer aboard the space station. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science.

  12. STS-119 Launch

    NASA Image and Video Library

    2009-03-15

    STS119-S-028 (15 March 2009) --- The Space Shuttle Discovery and its seven-member STS-119 crew head toward Earth orbit and a scheduled link-up with the International Space Station. Liftoff was on time at 7:43 p.m. (EDT) on March 15, 2009 from launch pad 39A at NASA’s Kennedy Space Center. Onboard are astronauts Lee Archambault, commander; Tony Antonelli, pilot; Joseph Acaba, Steve Swanson, Richard Arnold, John Phillips and Japan Aerospace Exploration Agency’s Koichi Wakata, all mission specialists. Wakata will join Expedition 18 in progress to serve as a flight engineer aboard the space station. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science.

  13. STS-119 Launch

    NASA Image and Video Library

    2009-03-15

    STS119-S-038 (15 March 2009) --- The Space Shuttle Discovery and its seven-member STS-119 crew head toward Earth orbit and a scheduled link-up with the International Space Station. Liftoff was on time at 7:43 p.m. (EDT) on March 15, 2009 from launch pad 39A at NASA’s Kennedy Space Center. Onboard are astronauts Lee Archambault, commander; Tony Antonelli, pilot; Joseph Acaba, Steve Swanson, Richard Arnold, John Phillips and Japan Aerospace Exploration Agency’s Koichi Wakata, all mission specialists. Wakata will join Expedition 18 in progress to serve as a flight engineer aboard the space station. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science.

  14. STS-119 Launch

    NASA Image and Video Library

    2009-03-15

    STS119-S-033 (15 March 2009) --- The Space Shuttle Discovery and its seven-member STS-119 crew head toward Earth orbit and a scheduled link-up with the International Space Station. Liftoff was on time at 7:43 p.m. (EDT) on March 15, 2009 from launch pad 39A at NASA’s Kennedy Space Center. Onboard are astronauts Lee Archambault, commander; Tony Antonelli, pilot; Joseph Acaba, Steve Swanson, Richard Arnold, John Phillips and Japan Aerospace Exploration Agency’s Koichi Wakata, all mission specialists. Wakata will join Expedition 18 in progress to serve as a flight engineer aboard the space station. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science.

  15. STS-119 Launch

    NASA Image and Video Library

    2009-03-15

    STS119-S-035 (15 March 2009) --- The Space Shuttle Discovery and its seven-member STS-119 crew head toward Earth orbit and a scheduled link-up with the International Space Station. Liftoff was on time at 7:43 p.m. (EDT) on March 15, 2009 from launch pad 39A at NASA’s Kennedy Space Center. Onboard are astronauts Lee Archambault, commander; Tony Antonelli, pilot; Joseph Acaba, Steve Swanson, Richard Arnold, John Phillips and Japan Aerospace Exploration Agency’s Koichi Wakata, all mission specialists. Wakata will join Expedition 18 in progress to serve as a flight engineer aboard the space station. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science.

  16. STS-119 Launch

    NASA Image and Video Library

    2009-03-15

    STS119-S-018 (15 March 2009) --- The Space Shuttle Discovery and its seven-member STS-119 crew head toward Earth orbit and a scheduled link-up with the International Space Station. Liftoff was on time at 7:43 p.m. (EDT) on March 15, 2009 from launch pad 39A at NASA’s Kennedy Space Center. Onboard are astronauts Lee Archambault, commander; Tony Antonelli, pilot; Joseph Acaba, Steve Swanson, Richard Arnold, John Phillips and Japan Aerospace Exploration Agency’s Koichi Wakata, all mission specialists. Wakata will join Expedition 18 in progress to serve as a flight engineer aboard the space station. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science.

  17. STS-119 Launch

    NASA Image and Video Library

    2009-03-15

    STS119-S-032 (15 March 2009) --- The Space Shuttle Discovery and its seven-member STS-119 crew head toward Earth orbit and a scheduled link-up with the International Space Station. Liftoff was on time at 7:43 p.m. (EDT) on March 15, 2009 from launch pad 39A at NASA’s Kennedy Space Center. Onboard are astronauts Lee Archambault, commander; Tony Antonelli, pilot; Joseph Acaba, Steve Swanson, Richard Arnold, John Phillips and Japan Aerospace Exploration Agency’s Koichi Wakata, all mission specialists. Wakata will join Expedition 18 in progress to serve as a flight engineer aboard the space station. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science.

  18. STS-119 Launch

    NASA Image and Video Library

    2009-03-15

    STS119-S-037 (15 March 2009) --- The Space Shuttle Discovery and its seven-member STS-119 crew head toward Earth orbit and a scheduled link-up with the International Space Station. Liftoff was on time at 7:43 p.m. (EDT) on March 15, 2009 from launch pad 39A at NASA’s Kennedy Space Center. Onboard are astronauts Lee Archambault, commander; Tony Antonelli, pilot; Joseph Acaba, Steve Swanson, Richard Arnold, John Phillips and Japan Aerospace Exploration Agency’s Koichi Wakata, all mission specialists. Wakata will join Expedition 18 in progress to serve as a flight engineer aboard the space station. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science.

  19. STS-119 Launch

    NASA Image and Video Library

    2009-03-15

    STS119-S-019 (15 March 2009) --- The Space Shuttle Discovery and its seven-member STS-119 crew head toward Earth orbit and a scheduled link-up with the International Space Station. Liftoff was on time at 7:43 p.m. (EDT) on March 15, 2009 from launch pad 39A at NASA’s Kennedy Space Center. Onboard are astronauts Lee Archambault, commander; Tony Antonelli, pilot; Joseph Acaba, Steve Swanson, Richard Arnold, John Phillips and Japan Aerospace Exploration Agency’s Koichi Wakata, all mission specialists. Wakata will join Expedition 18 in progress to serve as a flight engineer aboard the space station. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science.

  20. STS-119 Launch

    NASA Image and Video Library

    2009-03-15

    STS119-S-034 (15 March 2009) --- The Space Shuttle Discovery and its seven-member STS-119 crew head toward Earth orbit and a scheduled link-up with the International Space Station. Liftoff was on time at 7:43 p.m. (EDT) on March 15, 2009 from launch pad 39A at NASA’s Kennedy Space Center. Onboard are astronauts Lee Archambault, commander; Tony Antonelli, pilot; Joseph Acaba, Steve Swanson, Richard Arnold, John Phillips and Japan Aerospace Exploration Agency’s Koichi Wakata, all mission specialists. Wakata will join Expedition 18 in progress to serve as a flight engineer aboard the space station. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science.

  1. STS-119 Launch

    NASA Image and Video Library

    2009-03-15

    STS119-S-009 (15 March 2009) --- The Space Shuttle Discovery and its seven-member STS-119 crew head toward Earth orbit and a scheduled link-up with the International Space Station. Liftoff was on time at 7:43 p.m. (EDT) on March 15, 2009 from launch pad 39A at NASA’s Kennedy Space Center. Onboard are astronauts Lee Archambault, commander; Tony Antonelli, pilot; Joseph Acaba, Steve Swanson, Richard Arnold, John Phillips and Japan Aerospace Exploration Agency’s Koichi Wakata, all mission specialists. Wakata will join Expedition 18 in progress to serve as a flight engineer aboard the space station. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science.

  2. STS-119 Launch

    NASA Image and Video Library

    2009-03-15

    STS119-S-022 (15 March 2009) --- The Space Shuttle Discovery and its seven-member STS-119 crew head toward Earth orbit and a scheduled link-up with the International Space Station. Liftoff was on time at 7:43 p.m. (EDT) on March 15, 2009 from launch pad 39A at NASA’s Kennedy Space Center. Onboard are astronauts Lee Archambault, commander; Tony Antonelli, pilot; Joseph Acaba, Steve Swanson, Richard Arnold, John Phillips and Japan Aerospace Exploration Agency’s Koichi Wakata, all mission specialists. Wakata will join Expedition 18 in progress to serve as a flight engineer aboard the space station. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science.

  3. STS-119 Launch

    NASA Image and Video Library

    2009-03-15

    STS119-S-029 (15 March 2009) --- The Space Shuttle Discovery and its seven-member STS-119 crew head toward Earth orbit and a scheduled link-up with the International Space Station. Liftoff was on time at 7:43 p.m. (EDT) on March 15, 2009 from launch pad 39A at NASA’s Kennedy Space Center. Onboard are astronauts Lee Archambault, commander; Tony Antonelli, pilot; Joseph Acaba, Steve Swanson, Richard Arnold, John Phillips and Japan Aerospace Exploration Agency’s Koichi Wakata, all mission specialists. Wakata will join Expedition 18 in progress to serve as a flight engineer aboard the space station. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science.

  4. STS-119 Launch

    NASA Image and Video Library

    2009-03-15

    STS119-S-027 (15 March 2009) --- The Space Shuttle Discovery and its seven-member STS-119 crew head toward Earth orbit and a scheduled link-up with the International Space Station. Liftoff was on time at 7:43 p.m. (EDT) on March 15, 2009 from launch pad 39A at NASA’s Kennedy Space Center. Onboard are astronauts Lee Archambault, commander; Tony Antonelli, pilot; Joseph Acaba, Steve Swanson, Richard Arnold, John Phillips and Japan Aerospace Exploration Agency’s Koichi Wakata, all mission specialists. Wakata will join Expedition 18 in progress to serve as a flight engineer aboard the space station. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science.

  5. STS-119 Launch

    NASA Image and Video Library

    2009-03-15

    STS119-S-030 (15 March 2009) --- The Space Shuttle Discovery and its seven-member STS-119 crew head toward Earth orbit and a scheduled link-up with the International Space Station. Liftoff was on time at 7:43 p.m. (EDT) on March 15, 2009 from launch pad 39A at NASA’s Kennedy Space Center. Onboard are astronauts Lee Archambault, commander; Tony Antonelli, pilot; Joseph Acaba, Steve Swanson, Richard Arnold, John Phillips and Japan Aerospace Exploration Agency’s Koichi Wakata, all mission specialists. Wakata will join Expedition 18 in progress to serve as a flight engineer aboard the space station. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science.

  6. STS-119 Launch

    NASA Image and Video Library

    2009-03-15

    STS119-S-036 (15 March 2009) --- The Space Shuttle Discovery and its seven-member STS-119 crew head toward Earth orbit and a scheduled link-up with the International Space Station. Liftoff was on time at 7:43 p.m. (EDT) on March 15, 2009 from launch pad 39A at NASA’s Kennedy Space Center. Onboard are astronauts Lee Archambault, commander; Tony Antonelli, pilot; Joseph Acaba, Steve Swanson, Richard Arnold, John Phillips and Japan Aerospace Exploration Agency’s Koichi Wakata, all mission specialists. Wakata will join Expedition 18 in progress to serve as a flight engineer aboard the space station. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science.

  7. STS-119 Launch

    NASA Image and Video Library

    2009-03-15

    STS119-S-024 (15 March 2009) --- The Space Shuttle Discovery and its seven-member STS-119 crew head toward Earth orbit and a scheduled link-up with the International Space Station. Liftoff was on time at 7:43 p.m. (EDT) on March 15, 2009 from launch pad 39A at NASA’s Kennedy Space Center. Onboard are astronauts Lee Archambault, commander; Tony Antonelli, pilot; Joseph Acaba, Steve Swanson, Richard Arnold, John Phillips and Japan Aerospace Exploration Agency’s Koichi Wakata, all mission specialists. Wakata will join Expedition 18 in progress to serve as a flight engineer aboard the space station. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science.

  8. STS-119 Launch

    NASA Image and Video Library

    2009-03-15

    STS119-S-039 (15 March 2009) --- The Space Shuttle Discovery and its seven-member STS-119 crew head toward Earth orbit and a scheduled link-up with the International Space Station. Liftoff was on time at 7:43 p.m. (EDT) on March 15, 2009 from launch pad 39A at NASA’s Kennedy Space Center. Onboard are astronauts Lee Archambault, commander; Tony Antonelli, pilot; Joseph Acaba, Steve Swanson, Richard Arnold, John Phillips and Japan Aerospace Exploration Agency’s Koichi Wakata, all mission specialists. Wakata will join Expedition 18 in progress to serve as a flight engineer aboard the space station. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science.

  9. STS-119 Launch

    NASA Image and Video Library

    2009-03-15

    STS119-S-021 (15 March 2009) --- The Space Shuttle Discovery and its seven-member STS-119 crew head toward Earth orbit and a scheduled link-up with the International Space Station. Liftoff was on time at 7:43 p.m. (EDT) on March 15, 2009 from launch pad 39A at NASA’s Kennedy Space Center. Onboard are astronauts Lee Archambault, commander; Tony Antonelli, pilot; Joseph Acaba, Steve Swanson, Richard Arnold, John Phillips and Japan Aerospace Exploration Agency’s Koichi Wakata, all mission specialists. Wakata will join Expedition 18 in progress to serve as a flight engineer aboard the space station. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science.

  10. Reflective Random Indexing and indirect inference: a scalable method for discovery of implicit connections.

    PubMed

    Cohen, Trevor; Schvaneveldt, Roger; Widdows, Dominic

    2010-04-01

    The discovery of implicit connections between terms that do not occur together in any scientific document underlies the model of literature-based knowledge discovery first proposed by Swanson. Corpus-derived statistical models of semantic distance such as Latent Semantic Analysis (LSA) have been evaluated previously as methods for the discovery of such implicit connections. However, LSA in particular is dependent on a computationally demanding method of dimension reduction as a means to obtain meaningful indirect inference, limiting its ability to scale to large text corpora. In this paper, we evaluate the ability of Random Indexing (RI), a scalable distributional model of word associations, to draw meaningful implicit relationships between terms in general and biomedical language. Proponents of this method have achieved comparable performance to LSA on several cognitive tasks while using a simpler and less computationally demanding method of dimension reduction than LSA employs. In this paper, we demonstrate that the original implementation of RI is ineffective at inferring meaningful indirect connections, and evaluate Reflective Random Indexing (RRI), an iterative variant of the method that is better able to perform indirect inference. RRI is shown to lead to more clearly related indirect connections and to outperform existing RI implementations in the prediction of future direct co-occurrence in the MEDLINE corpus. 2009 Elsevier Inc. All rights reserved.

  11. Pharmacokinetics and therapeutic effect of OROS methylphenidate under different breakfast conditions in children with attention-deficit/hyperactivity disorder.

    PubMed

    Wigal, Sharon B; Gupta, Suneel; Heverin, Erica; Starr, H Lynn

    2011-06-01

    To examine the pharmacokinetics (PKs) and pharmacodynamics (PDs) of OROS methylphenidate (OROS MPH) dosed once daily (QD) versus an early standard regimen (immediate-release [IR] MPH dosed three times daily [TID]) under various breakfast conditions. This single-center, double-blind, double-dummy, randomized, crossover study of OROS MPH (NCT00269815) in children aged 6 to 12 years with attention-deficit/hyperactivity disorder evaluated the PKs and PDs of MPH given with different breakfast conditions: OROS MPH administered after a high-fat breakfast, after a normal breakfast, or after fasting and IR MPH administered after a normal breakfast or after fasting in the morning and at two subsequent time points during the day. To maximize information, patients were divided into two groups, each receiving three of the five treatments for 1 day in a three-period, randomized, crossover design. Patients were assigned to 1 of 3 dosage levels (OROS MPH 18, 36, and 54 mg QD, and an assumed equivalent regimen of IR MPH 5, 10, and 15 mg given TID) based on their prestudy established clinical dose of IR MPH. PD measurements included Combined-Attention and Deportment scores on a rating scale of school behavior (the Swanson, Kotkin, Agler, M-Flynn, and Pelham), global assessments of efficacy, and activity monitor levels during academic seatwork. Serial blood samples for PK analysis were taken predose, and then every 60 to 90 minutes until 11.5 hours postdose. Vital signs were assessed predose, and then every 1.5 to 2.5 hours until 11.5 hours postdose. Of the 32 patients enrolled, 31 completed the study. The PK profiles for MPH after OROS MPH administration were similar under all conditions (with normal, high-fat breakfast, or fasting). No bioequivalence tests of OROS MPH and IR MPH under various breakfast conditions were done because there were so few patients in each dose level of treatment. The two IR MPH conditions (after normal breakfast and fasting) were not compared. The drug-to-metabolite ratios (area under the curve) for all OROS MPH and IR MPH treatments were similar. OROS MPH and IR MPH provided a similar therapeutic effect, irrespective of breakfast conditions, as demonstrated by the Swanson, Kotkin, Agler, M-Flynn, and Pelham Attention and Deportment measures and global assessments. No serious adverse events, no deaths, and no clinically significant changes in vital signs were reported, except for one patient who was discontinued early because of repeated systolic blood pressure elevations on study day 1. The results of this study demonstrate that in children with attention-deficit/hyperactivity disorder, administering OROS MPH with or without food produces similar PK and PD profiles.

  12. Dueling Volcanoes: How Activity Levels At Kilauea Influence Eruptions At Mauna Loa

    NASA Astrophysics Data System (ADS)

    Trusdell, F.

    2011-12-01

    The eruption of Kilauea at Pu`u `O`o is approaching its 29th anniversary. During this time, Mauna Loa has slowly inflated following its most recent eruption in 1984. This is Mauna Loa's longest inter-eruptive interval observed in HVO's 100 years of operation. When will the next eruption of Mauna Loa take place? Is the next eruption of Mauna Loa tied to the current activity at Kilauea? Historically, eruptive periods at Kilauea and Mauna Loa volcanoes appear to be inversely correlated. In the past, when Mauna Loa was exceptionally active, Kilauea Volcano was in repose, recovery, or in sustained lava lake activity. Swanson and co-workers (this meeting) have noted that explosive activity on Kilauea, albeit sporadic, was interspersed between episodes of effusive activity. Specifically, Swanson and co-workers note as explosive the time periods between 300 B.C.E.-1000 C.E and 1500-1800 C.E. They also point to evidence for low magma supply to Kilauea during these periods and few flank eruptions. During the former explosive period, Mauna Loa was exceedingly active, covering approximately 37% of its surface or 1882 km2, an area larger than Kilauea. This period is also marked by summit activity at Mauna Loa sustained for 300 years. In the 1500-1800 C.E. period, Mauna Loa was conspicuously active with 29 eruptions covering an area of 446 km2. In the late 19th and early 20th century, Kilauea was dominated by nearly continuous lava-lake activity. Meanwhile Mauna Loa was frequently active from 1843 C.E. to 1919 C.E., with 24 eruptions for an average repose time of 3.5 years. I propose that eruptive activity at one volcano may affect eruptions at the other, due to factors that impact magma supply, volcanic plumbing, and flank motion. This hypothesis is predicated on the notion that when the rift zones of Kilauea, and in turn its mobile south flank, are active, Mauna Loa's tendency to erupt is diminished. Kilauea's rift zones help drive the south flank seaward, in turn, as Mauna Loa inflates its flank is not buttressed on the southeast. Consequently, asymmetrical spreading occurs resulting in dilation of the shallow magma storage centers, which ultimately culminates in decreased magma pressure and therefore lessened ability to erupt. Whether or not this hypothesis is accurate, there is growing geologic evidence for inverse activity levels at both volcanoes. This hypothesis is readily testable and can have profound implications on how we monitor shield volcanoes, which impacts our ability to forecast eruptions, conduct hazard assessments, and risk analysis.

  13. KSC-2014-2909

    NASA Image and Video Library

    2014-06-11

    CAPE CANAVERAL, Fla. – At far right, Jim Smodell, a technician with SGT, shows a plant pillow from the Veggie plant growth system to Gioia Massa, NASA payload scientist for Veggie. Partially hidden behind Smodell is Chuck Spern, lead project engineer with QinetiQ North America on the Engineering Services Contract. At left is Trent Smith, NASA project manager in the ISS Ground Processing and Research Project Office, and Nicole Dufour, NASA Engineering and Technology Directorate. They are in the Payload Development Laboratory at the Space Station Processing Facility, or SSPF, at NASA's Kennedy Space Center in Florida. The plant pillows were removed from the Veggie plant growth system inside a control chamber at the SSPF. The growth chamber was used as a control unit for Veggie and procedures were followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station. The chamber mimicked the temperature, relative humidity and carbon dioxide concentration of those in the Veggie unit on the space station. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth was monitored for 33 days. On June 10, at the end of the cycle, the plants were carefully harvested, frozen and stored for return to Earth by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Photo credit: NASA/Frankie Martin

  14. KSC-2014-2905

    NASA Image and Video Library

    2014-06-11

    CAPE CANAVERAL, Fla. – The plant pillows containing the outredgeous red lettuce leaves have been removed from the Veggie plant growth system inside a control chamber at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida. From left, are Trent Smith, NASA project manager in the ISS Ground Processing and Research Project Office, Chuck Spern, lead project engineer with QinetiQ North America on the Engineering Services Contract, George Guerra, quality control engineer with QinetiQ North America, Jim Smodell, a technician with SGT, Gioia Massa, NASA payload scientist for Veggie, and Nicole Dufour, NASA Engineering and Technology. The growth chamber was used as a control unit for Veggie and procedures were followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station. The chamber mimicked the temperature, relative humidity and carbon dioxide concentration of those in the Veggie unit on the space station. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth was monitored for 33 days. On June 10, at the end of the cycle, the plants were carefully harvested, frozen and stored for return to Earth by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Photo credit: NASA/Frankie Martin

  15. KSC-2014-2902

    NASA Image and Video Library

    2014-06-11

    CAPE CANAVERAL, Fla. – Jim Smodell, a technician with SGT, moves the plant pillows containing the outredgeous red lettuce leaves outside of the International Space Station Environmental Simulator chamber at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida. The growth chamber was used as a control unit for Veggie and procedures were followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station. In the background is Chuck Spern, lead project engineer with QinetiQ North America on the Engineering Services Contract. The chamber mimicked the temperature, relative humidity and carbon dioxide concentration of those in the Veggie unit on the space station. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth was monitored for 33 days. On June 10, at the end of the cycle, the plants were carefully harvested, frozen and stored for return to Earth by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Photo credit: NASA/Frankie Martin

  16. KSC-2014-2903

    NASA Image and Video Library

    2014-06-11

    CAPE CANAVERAL, Fla. – Jim Smodell, left, a technician with SGT, and Chuck Spern, lead project engineer with QinetiQ North America on the Engineering Services Contract, move the plant pillows containing the outredgeous red lettuce leaves outside of the International Space Station Environmental Simulator chamber at the Space Station Processing Facility at NASA's Kennedy Space Center in Florida. The growth chamber was used as a control unit for Veggie and procedures were followed identical to those being performed on Veggie and the Veg-01 experiment on the International Space Station. The chamber mimicked the temperature, relative humidity and carbon dioxide concentration of those in the Veggie unit on the space station. Veggie and Veg-01 were delivered to the space station aboard the SpaceX-3 mission. Veggie is the first fresh food production system delivered to the station. Six plant pillows, each containing outredgeous red romaine lettuce seeds and a root mat were inserted into Veggie. The plant chamber's red, blue and green LED lights were activated. The plant growth was monitored for 33 days. On June 10, at the end of the cycle, the plants were carefully harvested, frozen and stored for return to Earth by Expedition 39 flight engineer and NASA astronaut Steve Swanson. Photo credit: NASA/Frankie Martin

  17. Development of the oil-water monitor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Swanson, C.

    1990-04-02

    The oil-water monitor is a device invented by Dr. Claude Swanson of Applied Physics Technology to respond to the petroleum-loss problem in crude oil transfers. It is a device which measures water content in crude oil and other petroleum products, in a flowing pipe such as a pipeline or tanker manifold. It is capable of accurately measuring the water contamination levels in crude oil shipments, in real time as the crude oil flows through the loading manifold into the tanker, or at the receiving point as the oil is off-loaded It has application in the verification of oil volumes andmore » concentration of contaminants at petroleum transfer points. The industry-estimated level of water loss at transfer points due to inadequate monitoring technology amounts to several billion dollars per year, so there is a definite perceived need within the petroleum community for this type of accurate water monitoring technology. The device has been patented, and initial feasibility experiments have been conducted. The present research is directed toward developing and demonstrating a bench model prototype of the oil-water monitor, complete with the computer software and automated microwave equipment and electronics which will demonstrate the performance of the invention, for implementation in full-scale fielded systems. 3 figs.« less

  18. KSC-07pd0472

    NASA Image and Video Library

    2007-02-21

    KENNEDY SPACE CENTER, FLA. -- At Launch Complex 39, STS-117 Mission Specialist Steven Swanson is helmeted and ready to practice driving an M-113 armored personnel carrier. The astronauts on the STS-117 crew are participating in M-113 armored personnel carrier training during Terminal Countdown Demonstration Test (TCDT) activities, a dress rehearsal for their launch, targeted for March 15. The M-113 could be used to move the crew away from the launch pad quickly in the event of an emergency. The TCDT also includes pad emergency egress training and a simulated launch countdown. The mission payload aboard Space Shuttle Atlantis is the S3/S4 integrated truss structure, along with a third set of solar arrays and batteries. The crew of six astronauts will install the truss to continue assembly of the station. Photo credit: NASA/Kim Shiflett

  19. The influence of inattention and rapid automatized naming on reading performance.

    PubMed

    Pham, Andy V; Fine, Jodene Goldenring; Semrud-Clikeman, Margaret

    2011-04-01

    The current study examined the relation between attention, rapid automatized naming (RAN), and reading fluency among typically developing children. A total of 104 third- and fourth-grade children (8-11 years of age) completed RAN measures consisting of four stimuli (letter, digit, color, and object) and an oral reading fluency measure from the Gray Oral Reading Test-Fourth Edition. Correlational and hierarchical regression analyses revealed that all four RAN stimuli, particularly letter RAN, were significant predictors of reading fluency. Additionally, parent and teacher ratings of inattention from the Swanson, Nolan and Pelham-Version Four rating scale predicted RAN after controlling for gender, working memory, and estimated IQ. Further analyses indicated that RAN performance mediated the relation between inattention and reading fluency. Results support the need to consider attentional variables when assessing reading performance, even among typically developing children.

  20. Level-Set Variational Implicit-Solvent Modeling of Biomolecules with the Coulomb-Field Approximation

    PubMed Central

    2011-01-01

    Central in the variational implicit-solvent model (VISM) [Dzubiella, Swanson, and McCammon Phys. Rev. Lett.2006, 96, 087802 and J. Chem. Phys.2006, 124, 084905] of molecular solvation is a mean-field free-energy functional of all possible solute–solvent interfaces or dielectric boundaries. Such a functional can be minimized numerically by a level-set method to determine stable equilibrium conformations and solvation free energies. Applications to nonpolar systems have shown that the level-set VISM is efficient and leads to qualitatively and often quantitatively correct results. In particular, it is capable of capturing capillary evaporation in hydrophobic confinement and corresponding multiple equilibrium states as found in molecular dynamics (MD) simulations. In this work, we introduce into the VISM the Coulomb-field approximation of the electrostatic free energy. Such an approximation is a volume integral over an arbitrary shaped solvent region, requiring no solutions to any partial differential equations. With this approximation, we obtain the effective boundary force and use it as the “normal velocity” in the level-set relaxation. We test the new approach by calculating solvation free energies and potentials of mean force for small and large molecules, including the two-domain protein BphC. Our results reveal the importance of coupling polar and nonpolar interactions in the underlying molecular systems. In particular, dehydration near the domain interface of BphC subunits is found to be highly sensitive to local electrostatic potentials as seen in previous MD simulations. This is a first step toward capturing the complex protein dehydration process by an implicit-solvent approach. PMID:22346739

  1. Language-learning disabilities: Paradigms for the nineties.

    PubMed

    Wiig, E H

    1991-01-01

    We are beginning a decade, during which many traditional paradigms in education, special education, and speech-language pathology will undergo change. Among paradigms considered promising for speech-language pathology in the schools are collaborative language intervention and strategy training for language and communication. This presentation introduces management models for developing a collaborative language intervention process, among them the Deming Management Method for Total Quality (TQ) (Deming 1986). Implementation models for language assessment and IEP planning and multicultural issues are also introduced (Damico and Nye 1990; Secord and Wiig in press). While attention to processes involved in developing and implementing collaborative language intervention is paramount, content should not be neglected. To this end, strategy training for language and communication is introduced as a viable paradigm. Macro- and micro-level process models for strategy training are featured and general issues are discussed (Ellis, Deshler, and Schumaker 1989; Swanson 1989; Wiig 1989).

  2. A Three-Component Model for Magnetization Transfer. Solution by Projection-Operator Technique, and Application to Cartilage

    NASA Astrophysics Data System (ADS)

    Adler, Ronald S.; Swanson, Scott D.; Yeung, Hong N.

    1996-01-01

    A projection-operator technique is applied to a general three-component model for magnetization transfer, extending our previous two-component model [R. S. Adler and H. N. Yeung,J. Magn. Reson. A104,321 (1993), and H. N. Yeung, R. S. Adler, and S. D. Swanson,J. Magn. Reson. A106,37 (1994)]. The PO technique provides an elegant means of deriving a simple, effective rate equation in which there is natural separation of relaxation and source terms and allows incorporation of Redfield-Provotorov theory without any additional assumptions or restrictive conditions. The PO technique is extended to incorporate more general, multicomponent models. The three-component model is used to fit experimental data from samples of human hyaline cartilage and fibrocartilage. The fits of the three-component model are compared to the fits of the two-component model.

  3. Attention deficit hyperactivity symptoms in children with autistic disorder: a cross-sectional descriptive study.

    PubMed

    Charnsil, Chawanun; Sriapai, Payupol

    2011-02-01

    (1) to examine the co-occurrence of attention deficit and hyperactivity symptoms in children with autistic disorder, and (2) to study the correlation between attention deficit hyperactivity symptoms and the severity of autistic disorder. This was a clinical based study. The authors used Childhood Autistic Rating scale (CARs) to evaluate the severity of autistic disorder Swanson, Nolan, and Pelham Teacher and Parent Rating Scale, Version IV (SNAP-IV) was used to measure attention deficit and hyperactive symptoms in children with autism. Thirty (n=30) children enrolled in this study. All participants displayed attention deficit symptoms and 18 participants demonstrated hyperactivity as well. Nonparametric correlation showed a high positive correlation (Spa = 0.90, p = 0.00) between the severity of autistic disorder and hyperactivity and not the attention deficit symptoms (Spa = 0.29, p = 0.16). The authors finding shows a high comorbid rate of attention deficit and hyperactive symptoms among the participants.

  4. STS117-S-020

    NASA Image and Video Library

    2007-06-08

    STS117-S-020 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  5. STS117-S-009

    NASA Image and Video Library

    2007-06-08

    STS117-S-009 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  6. STS117-S-011

    NASA Image and Video Library

    2007-06-08

    STS117-S-011 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  7. STS117-S-017

    NASA Image and Video Library

    2007-06-08

    STS117-S-017 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  8. STS117-S-039

    NASA Image and Video Library

    2007-06-08

    STS117-S-039 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  9. STS117-S-016

    NASA Image and Video Library

    2007-06-08

    STS117-S-016 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  10. STS117-S-019

    NASA Image and Video Library

    2007-06-08

    STS117-S-019 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  11. STS117-S-006

    NASA Image and Video Library

    2007-06-08

    STS117-S-006 (8 June 2007) --- After suiting up, the STS-117 crewmembers exit the Operations and Checkout Building to board the Astrovan, which will take them to launch pad 39A at Kennedy Space Center. On the right (front to back) are astronauts Rick Sturckow, commander; Steven Swanson, Clayton Anderson and Jim Reilly (center back), all mission specialists. On the left (front to back) are astronauts Lee Archambault, pilot; Patrick Forrester and John "Danny" Olivas, both mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the International Space Station. Atlantis will link up with the International Space Station on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  12. STS117-S-030

    NASA Image and Video Library

    2007-06-08

    STS117-S-030 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  13. STS117-S-027

    NASA Image and Video Library

    2007-06-08

    STS117-S-027 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  14. STS117-S-008

    NASA Image and Video Library

    2007-06-08

    STS117-S-008 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  15. STS117-S-007

    NASA Image and Video Library

    2007-06-08

    STS117-S-007 (8 June 2007) --- After suiting up, the STS-117 crewmembers exit the Operations and Checkout Building to board the Astrovan, which will take them to launch pad 39A at Kennedy Space Center. On the right (front to back) are astronauts Rick Sturckow, commander; Steven Swanson, Clayton Anderson and Jim Reilly, all mission specialists. On the left (front to back) are astronauts Lee Archambault, pilot; Patrick Forrester and John "Danny" Olivas, both mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the International Space Station. Atlantis will link up with the International Space Station on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  16. STS117-S-018

    NASA Image and Video Library

    2007-06-08

    STS117-S-018 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  17. STS117-S-010

    NASA Image and Video Library

    2007-06-08

    STS117-S-010 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  18. STS117-S-034

    NASA Image and Video Library

    2007-06-08

    STS117-S-034 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  19. STS117-S-028

    NASA Image and Video Library

    2007-06-08

    STS117-S-028 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  20. STS117-S-026

    NASA Image and Video Library

    2007-06-08

    STS117-S-026 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  1. STS117-S-033

    NASA Image and Video Library

    2007-06-08

    STS117-S-033 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  2. STS117-S-031

    NASA Image and Video Library

    2007-06-08

    STS117-S-031 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  3. STS117-S-037

    NASA Image and Video Library

    2007-06-08

    STS117-S-037 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  4. STS117-S-035

    NASA Image and Video Library

    2007-06-08

    STS117-S-035 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  5. STS117-S-036

    NASA Image and Video Library

    2007-06-08

    STS117-S-036 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  6. STS117-S-023

    NASA Image and Video Library

    2007-06-08

    STS117-S-023 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  7. STS117-S-038

    NASA Image and Video Library

    2007-06-08

    STS117-S-038 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  8. STS117-S-015

    NASA Image and Video Library

    2007-06-08

    STS117-S-015 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  9. STS117-S-024

    NASA Image and Video Library

    2007-06-08

    STS117-S-024 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  10. STS117-S-025

    NASA Image and Video Library

    2007-06-08

    STS117-S-025 (8 June 2007) --- The Space Shuttle Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  11. ADHD and nicotine use in schizophrenia or Asperger syndrome: a controlled study.

    PubMed

    Hallerbäck, Maria Unenge; Lugnegård, Tove; Gillberg, Christopher

    2014-07-01

    To examine ADHD prevalence, rating scales, and relationship to nicotine use in adults with schizophrenia or Asperger syndrome. Ninety-five individuals, 41 with schizophrenia and 54 with Asperger syndrome, were included. Self-rating of adult ADHD symptoms with the Wender-Reimherr Adult Attention Deficit Diagnostic Rating Scale (WRAADDS), parent rating of proband's ADHD childhood and adult life symptoms using the Swanson, Nolan, and Pelham Questionnaire (SNAP), and report of clinical ADHD diagnosis were included as ADHD measures. Nicotine use data were compared with data from a population sample. In all, 10% of the schizophrenia group and 30% of the Asperger syndrome group had a clinical ADHD diagnosis. Nicotine dependency in the whole sample was closely linked to ADHD. The prevalence of comorbid ADHD was high in schizophrenia and Asperger syndrome. The WRAADDS self-rating scale for ADHD can be one useful tool for assessing comorbid ADHD in these patient groups. © 2012 SAGE Publications.

  12. KSC-07pd1362

    NASA Image and Video Library

    2007-06-04

    KENNEDY SPACE CENTER, FLA. -- After their arrival at KSC, STS-117 crew members take part in a payload bay walkdown on Launch Pad 39A to look at the cargo in Space Shuttle Atlantis. In the bucket are Mission Specialists Patrick Forrester (with camera) and Steven Swanson (far right). The payload includes the S3/S4 integrated truss structure for the International Space Station. STS-117 is scheduled to launch at 7:38 p.m. June 8. During the 11-day mission and three spacewalks, the crew will work with flight controllers at NASA's Johnson Space Center in Houston to install the 17-ton segment on the station's girder-like truss and deploy the set of solar arrays, S3/S4. The mission will increase the space station's power capability in preparation for the arrival of new science modules from the European and Japanese space agencies. Photo credit: NASA/Kim Shiflett

  13. Editorial: The continuing contributions of multimodal treatment of attention over nearly two decades to initial attention-deficit hyperactivity disorder pharmacotherapy and long-term clinical course.

    PubMed

    Bloch, Michael H

    2017-06-01

    The initial results of the Multimodal Treatment of Attention Deficit Hyperactivity Disorder (MTA) trial had profound effects on the way that Attention-Deficit Hyperactivity Disorder (ADHD) is managed clinically. Children from the original MTA cohort as well as a control group have been followed longitudinally for well over a decade and are beginning to provide important data regarding the long-term clinical course, treatment and consequences of ADHD into adulthood. Two articles in this issue of JCPP highlight important contributions from the MTA cohort. Swanson et al. highlights the potential long-term effects of stimulants on height whereas Sibley et al. highlights the importance of using multiple informants in assessing adulthood ADHD symptoms similar to children and suggest that current DSM criteria for ADHD may be overly stringent. © 2017 Association for Child and Adolescent Mental Health.

  14. Outstanding conference paper award 2014 IEEE nuclear and space radiation effects conference

    DOE PAGES

    Dodds, Nathaniel Anson; Schwank, James R.; Shaneyfelt, Marty R.; ...

    2014-12-01

    The recipients of the 2014 NSREC Outstanding Conference Paper Award are Nathaniel A. Dodds, James R. Schwank, Marty R. Shaneyfelt, Paul E. Dodd, Barney L. Doyle, Michael Trinczek, Ewart W. Blackmore, Kenneth P. Rodbell, Michael S. Gordon, Robert A. Reed, Jonathan A. Pellish, Kenneth A. LaBel, Paul W. Marshall, Scot E. Swanson, Gyorgy Vizkelethy, Stuart Van Deusen, Frederick W. Sexton, and M. John Martinez, for their paper entitled "Hardness Assurance for Proton Direct Ionization-Induced SEEs Using a High-Energy Proton Beam." For older CMOS technologies, protons could only cause single-event effects (SEEs) through nuclear interactions. Numerous recent studies on 90 nmmore » and newer CMOS technologies have shown that protons can also cause SEEs through direct ionization. Furthermore, this paper develops and demonstrates an accurate and practical method for predicting the error rate caused by proton direct ionization (PDI).« less

  15. Outstanding conference paper award 2014 IEEE nuclear and space radiation effects conference

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dodds, Nathaniel Anson; Schwank, James R.; Shaneyfelt, Marty R.

    The recipients of the 2014 NSREC Outstanding Conference Paper Award are Nathaniel A. Dodds, James R. Schwank, Marty R. Shaneyfelt, Paul E. Dodd, Barney L. Doyle, Michael Trinczek, Ewart W. Blackmore, Kenneth P. Rodbell, Michael S. Gordon, Robert A. Reed, Jonathan A. Pellish, Kenneth A. LaBel, Paul W. Marshall, Scot E. Swanson, Gyorgy Vizkelethy, Stuart Van Deusen, Frederick W. Sexton, and M. John Martinez, for their paper entitled "Hardness Assurance for Proton Direct Ionization-Induced SEEs Using a High-Energy Proton Beam." For older CMOS technologies, protons could only cause single-event effects (SEEs) through nuclear interactions. Numerous recent studies on 90 nmmore » and newer CMOS technologies have shown that protons can also cause SEEs through direct ionization. Furthermore, this paper develops and demonstrates an accurate and practical method for predicting the error rate caused by proton direct ionization (PDI).« less

  16. The trajectory of scientific discovery: concept co-occurrence and converging semantic distance.

    PubMed

    Cohen, Trevor; Schvaneveldt, Roger W

    2010-01-01

    The paradigm of literature-based knowledge discovery originated by Swanson involves finding meaningful associations between terms or concepts that have not occurred together in any previously published document. While several automated approaches have been applied to this problem, these generally evaluate the literature at a point in time, and do not evaluate the role of change over time in distributional statistics as an indicator of meaningful implicit associations. To address this issue, we develop and evaluate Symmetric Random Indexing (SRI), a novel variant of the Random Indexing (RI) approach that is able to measure implicit association over time. SRI is found to compare favorably to existing RI variants in the prediction of future direct co-occurrence. Summary statistics over several experiments suggest a trend of converging semantic distance prior to the co-occurrence of key terms for two seminal historical literature-based discoveries.

  17. Association Between Age of Beginning Primary School and Attention Deficit Hyperactivity Disorder.

    PubMed

    Gökçe, Sebla; Yazgan, Yanki; Ayaz, Ayşe Burcu; Kayan, Esengül; Yusufoğlu, Canan; Carkaxhiu Bulut, Gresa; Aslan Genç, Herdem; Dedeoğlu, Ceyda; Demirhan, Seçil; Sancak, Arzu; Saridoğan, Gökçe Elif

    2017-01-01

    In April 2012, the Turkish national education system was modified, and the compulsory school age of entry (first grade) was redefined as a minimum of 60 months and a maximum of 66 months (replacing the former minimum criterion of 72 months). In this study, we hypothesized that students starting school before 72 months (the previous age standard for the first grade) may experience (1) a greater number of symptoms of attention deficit hyperactivity disorder (ADHD) and (2) lower functioning in social, behavioral, and academic domains. We performed a cross-sectional community-based study in the first and second grades of all primary schools (4356 students) located in the Kadıköy county of Istanbul, Turkey. Teachers completed Swanson, Nolan, and Pelham version IV and Conners' Teacher's report forms for symptoms of ADHD, the Perceived Competence Scale for functioning, and a sociodemographic questionnaire. Among first graders, the group that began primary school before the age of 72 months had a higher ADHD prevalence than both of the groups that began primary school between the ages of 72 to 77 months and 78 to 83 months (p < .001 for both groups). ADHD symptoms diminished and academic, social, and behavioral functioning improved with age for the first and second grade students. The probability of displaying ADHD symptoms (and caseness) is greater among the "earlier" beginners, whereas the "conventional" classmates exhibited better academic, social, and behavioral functioning.

  18. Final report on development and testing of the microwave oil-water monitor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Swanson, C.

    1991-06-15

    The oil-water monitor is a device invented by Dr. Claude Swanson of Applied Physics Technology to respond to the petroleum-loss problem in crude oil transfers. It is a device which measures water content in crude oil and other petroleum products, in a flowing pipe such as a pipeline or tanker manifold. It is capable of accurately measuring the water contamination levels in crude oil shipments, in real time as the crude oil flows through the loading manifold into the tanker, or at the receiving point as the oil is off-loaded. The oil-water monitor has application in the verification of oilmore » volumes and concentration of contaminants at petroleum transfer points. The industry-estimated level of water loss at transfer points due to inadequate monitoring technology amounts to several billion dollars per year, so there is a definite perceived need within the petroleum community for this type of accurate water monitoring technology. News articles indicating the importance of this problem are shown. The microwave oil-water monitor measures the water content in the oil, whether in the form of small droplets or large globules. Therefore it can be applied to the crude oil as it flows through crude oil pipes into the ship, or at transfer points in a crude oil distribution system. 4 refs., 18 figs.« less

  19. Regional Stratigraphy and Petroleum Systems of the Illinois Basin, U.S.A.

    USGS Publications Warehouse

    Swezey, Christopher S.

    2009-01-01

    The publication combines data on Paleozoic and Mesozoic stratigraphy and petroleum geology of the Illinois basin, U.S.A., in order to facilitate visualizing the stratigraphy on a regional scale and visualizing stratigraphic relations within the basin. Data are presented in eight schematic chronostratigraphic sections arranged approximately from north to south, with time denoted in equal increments along the sections, in addition to the areal extent of this structural basin. The stratigraphic data are modified from Hass (1956), Conant and Swanson (1961), Wilman and others (1975), American Association of Petroleum Geologists (1984, 1986), Olive and McDowell (1986), Shaver and others (1986), Thompson (1986), Mancini and others (1996), and Harrison and Litwin (1997). The time scale is taken from Gradstein and others (2004). Additional stratigraphic nomenclature is from Harland and others (1990), Babcock and others (2007), and Bergstrom and others (2008). Stratigraphic sequences as defined by Sloss (1963, 1988) and Wheeler (1963) also are included, as well as the locations of major petroleum source rocks and major petroleum plays. The stratigraphic units shown are colored according to predominant lithology, in order to emphasize general lithologic patterns and to provide a broad overview of the Illinois basin. For the purpose of comparison, three columns on the right show schematic depictions of stratigraphy and interpreted events in the Illinois basin and in the adjacent Michigan and Appalachian basins.

  20. Preliminary Geologic Map of the Mount Hood 30- by 60-minute Quadrangle, Northern Cascade Range, Oregon

    USGS Publications Warehouse

    Sherrod, David R.; Scott, William E.

    1995-01-01

    This map shows the geology of the central and eastern parts of the Cascade Range in northern Oregon. The Quaternary andesitic stratovolcano of Mount Hood dominates the northwest quarter of the quadrangle, but nearly the entire area is underlain by arc-related volcanic and volcaniclastic rocks of the Cascade Range. Most stratigraphic units were emplaced since middle Miocene time, and all are Oligocene or younger. Despite the proximity of the map area to the Portland metropolitan area, large parts remained virtually unstudied or known only from limited reconnaissance until the late 1970s. A notable exception is the area surrounding Mount Hood, where mapping and chemical analyses by Wise (1969) provided a framework for geologic interpretation. Mapping since 1975 was conducted first to understand the stratigraphy and structure of the Columbia River Basalt Group (Anderson, 1978; Vogt, 1981; J.L. Anderson, in Swanson and others, 1981; Vandiver-Powell, 1978; Burck, 1986) and later to examine the geothermal potential of Mount Hood (Priest and others, 1982). Additional mapping was completed in 1985 for a geologic map of the Cascade Range in Oregon (Sherrod and Smith, 1989). From 1987 to 1990, detailed mapping was conducted in three 15-minute quadrangles on a limited basis (D.R. Sherrod, unpublished mapping) (see fig. 1 for index to mapping). An ongoing volcanic hazards study of Mount Hood by the U.S. Geological Survey (Scott and others, 1994) has provided the catalyst for completing the geologic map of the Mount Hood 30-minute by 60-minute quadrangle. As of June 1994, only two broad areas still remain largely unmapped. One of these areas, labeled 'unmapped' on the geologic map, lies in the Salmon River valley south of Zigzag along the west margin of the quadrangle. Although strata of the Columbia River Basalt Group in the Salmon River valley were mapped in detail by Burck (1986), the overlying middle and upper(?) Miocene lava flows, volcaniclastic strata, and intrusions have never been studied. The other poorly known area, the Mutton Mountains in the southeastern part of the map area, consists of Oligocene and lower Miocene volcanic and volcaniclastic rocks. Overlying lava flows of the Columbia River Basalt Group were mapped in some detail by Anderson (in Swanson and others, 1981).

  1. Landslide hazard and forest fires - the relevance of geology for landslide type and development

    NASA Astrophysics Data System (ADS)

    Fernandez-Steeger, Tomas M.; Wiatr, Thomas; Papanikolaou, Ioannis; Reicherter, Klaus

    2010-05-01

    Current research indicates an increasing number of forest fires incidents and burned areas for Europe in the future (e.g. Moriondo et al., 2006). Besides economical and environmental impacts they can cause future "secondary" hazards like landslides, debris flows and flash floods. There are many past and current studies investigating effects of erosion and landslide phenomena like debris flows in burned areas (s. Shakesby & Doerr, 2006). The influence of the geological framework is often neglected in these studies. Furthermore, deep seated landslides and slumps are only hypothetically described (Swanson, 1981). To study the relevance of geology and to observe the processes, areas in Attica and the western Peloponnese in Greece burned by the catastrophic wildfires of 2007 and 2009 were investigated. The Tertiary Flysch units and the Neogene deposits in the Pyrgos area of the western Peloponnese are generally a landslide prone area. The slopes in the area show the typical morphological features of a landslide landscape. This is not only true for the in 2007 burned areas but also for unburned areas even in some kilometre distance. Large rotational slides with 20 m and higher main scarps interact and build up complex staircase landslide cascades. Even so vegetation indicates for the unburned areas currently a low activity. In contrary in the burned areas even 2 years after the fires many recent effects from landslides can be observed, like slope failures, cliff break ups, road failures, destroyed retention walls and cracks in houses. While the shallow landslides show a very high dynamic, also older larger landslides are developing or reactivating. As the changes in landslide activity are limited to the burned areas, it is reasonable that the changes in the hydrological conditions like Swanson (1981) predicted due to the destroyed vegetation are the main trigger mechanism for the new and reactivated landslides. An increased availability of water at the sliding plane and the additional weight of the saturated soils change substantially the limit equilibrium. In general the findings show that the changed environmental conditions due to the fires drastically increased the landslide activity in the area at least locally. In Attica, the affected areas are mostly located in Mesozoic metamorphic units build up from schist and marbles. As the fires stopped only two months before our site visit, the landslide effects are not that explicit and were just beginning to develop. Furthermore, due to the different geology and morphology the areas are not known as typical landslide areas. In the schist areas besides the development of rills and gullies, at several localities shallow soil slip with some 10 m extension could be observed. Anyhow the processes were limited to the weathered cover of the rocks which are much more permeable. On the other hand, in the marble areas only local erosion in the thin soil cover and first activation of debris could be observed. Anyhow, heavy precipitation events lead already to flooding. The results show that the type and extend of landslides which develop after a fire incident are also controlled by geological features like rock types or permeability. Moreover, in an appropriate landslide environment even very large landslides might develop after a forest fires. Moriondo, M. et al. 2006. Potential impact of climate change on fire risk in the Mediterranean area. Climate Res. 31, 85-95. Shakesby, R.A. & Doerr, S.H. 2006. Wildfire as a hydrological and geomorphological agent. Earth Sci. Rev. 74, 269- 307. Swanson, F.J., 1981. Fire and geomorphic processes. in: Mooney et al. (Eds.), Fire Regime and Ecosystem Properties, USDA For. Serv. Gen. Tech. Rep. WO-26, 401-421.

  2. Heterogeneity of shale documented by micro-FTIR and image analysis.

    PubMed

    Chen, Yanyan; Mastalerz, Maria; Schimmelmann, Arndt

    2014-12-01

    In this study, four New Albany Shale Devonian and Mississippian samples, with vitrinite reflectance [Ro ] values ranging from 0.55% to 1.41%, were analyzed by micro-FTIR mapping of chemical and mineralogical properties. One additional postmature shale sample from the Haynesville Shale (Kimmeridgian, Ro = 3.0%) was included to test the limitation of the method for more mature substrates. Relative abundances of organic matter and mineral groups (carbonates, quartz and clays) were mapped across selected microscale regions based on characteristic infrared peaks and demonstrated to be consistent with corresponding bulk compositional percentages. Mapped distributions of organic matter provide information on the organic matter abundance and the connectivity of organic matter within the overall shale matrix. The pervasive distribution of organic matter mapped in the New Albany Shale sample MM4 is in agreement with this shale's high total organic carbon abundance relative to other samples. Mapped interconnectivity of organic matter domains in New Albany Shale samples is excellent in two early mature shale samples having Ro values from 0.55% to 0.65%, then dramatically decreases in a late mature sample having an intermediate Ro of 1.15% and finally increases again in the postmature sample, which has a Ro of 1.41%. Swanson permeabilities, derived from independent mercury intrusion capillary pressure porosimetry measurements, follow the same trend among the four New Albany Shale samples, suggesting that micro-FTIR, in combination with complementary porosimetric techniques, strengthens our understanding of porosity networks. In addition, image processing and analysis software (e.g. ImageJ) have the capability to quantify organic matter and total organic carbon - valuable parameters for highly mature rocks, because they cannot be analyzed by micro-FTIR owing to the weakness of the aliphatic carbon-hydrogen signal. © 2014 The Authors Journal of Microscopy © 2014 Royal Microscopical Society.

  3. Stratigraphic sections of the phosphoria formation in Utah, 1949-1951

    USGS Publications Warehouse

    Cheney, T.M.; Smart, R.A.; Waring, R.G.; Warner, M.A.

    1953-01-01

    As part of a comprehensive investigation of the phosphate deposits of the western field begun in 1947, the U.S. Geological Survey has measured and sampled the full thickness of the Permian Phosphoria formation and its partial correlative, the Park City formation, at many localities in Utah and other states. Although these data will not be fully analyzed for several years, segments of the data, accompanied by little or no interpretation, are published as preliminary reports as they are assembled. This report, which contains abstracts of the sections measured in northeastern Utah in 1949, 1950, and 1951, is one of this series and the second report of data gathered in Utah. The field and laboratory procedures adopted in these investigations are described rather fully in a previous report (McKelvey and others, 1953a). Many people have taken part in this investigation. The program which this work is a part was organized by V. E. McKelvey and the field program was supervised by R. W. Swanson. R. P. Sheldon assisted in the location and selection of sample localities and F. J. Anderson, McKelvey, Sheldon, and H. W. Peirce participated in the description of strata and the collection of samples referred to in this report. T. K. Rigby assisted in the preparation of trenches and the crushing and splitting of samples in the field. The laboratory preparation of samples for chemical analysis was done in Denver, Colo., under the direction of W. P. Huleatt.

  4. The effect of cracking on the deflection basin of flexible pavements

    NASA Astrophysics Data System (ADS)

    Omar, Hadi Mohamed

    Because of the rapid development of hardware and software during the past decade, it is now possible to use an analytical-empirical (or mechanistic) method of structural pavement evaluation on a routine basis. One reason for using this approach is the increased need for pavement maintenance and rehabilitation. To make the right choice from many potentially feasible maintenance and rehabilitation measures, the engineer must base his decision on a rational evaluation of the mechanical properties of the materials in the existing pavement structure. One of the parameters in terms of pavement response are the deflections; these are of interest to this particular study. The Falling Weight Deflectometer (FWD) has been developed specifically for the purpose of obtaining deflection measurements in order to determine the in-situ elastic moduli. The profile of the deflection at the surface of the pavement is known as the deflection basin, because it resembles a bowl-shaped depression. The magnitude of the deflections and the basin shape are functions of the number of layers making up the pavement cross section, their thicknesses, and their moduli values. A variety of multi-layered linear elastic pavement models are available for use at this present time. A general-purpose finite-element program called ANSYS developed by Swanson Analysis System is very powerful and is capable of solving a layered system such as the pavement. A finite element model was developed to study the effect of the crack on the predicted deflection bowls. A general-purpose finite-element program was used in this study due to its ability to solve this problem and because of the availability of the program. A hypothetical crack problem was assumed and modeled in different ways. The crack depth, crack width, and distance of the crack from the loading point were among the many parameters that were investigated. Considering the shape of the deflection basin, it is very important to study the effect of the crack on this bowl, when and where the cracks can be ignored, and when they would not play a significant effect. This study also addresses the importance of the field data and how the observed deflection basins compare with the predicted ones especially in aged pavements. This study has concluded that the location of a crack from the loading point is very significant to the deflection basin.

  5. KSC-2009-2044

    NASA Image and Video Library

    2009-03-15

    CAPE CANAVERAL, Fla. – In the Operations and Checkout Building at NASA's Kennedy Space Center in Florida, STS-119 Mission Specialist Steve Swanson adjusts his helmet as he puts on the launch-and-entry suit for the launch of space shuttle Discovery. The crew will be heading for Launch Pad 39A and liftoff of Discovery, scheduled for 7:43 p.m. EDT on March 15. An earlier launch attempt March 11 was scrubbed at 2:36 p.m. due to a gaseous hydrogen leak from the external tank at the Ground Umbilical Carrier Plate during tanking. A seven-inch quick disconnect and two seals were replaced. The STS-119 mission is the 28th to the International Space Station and the 125th space shuttle flight. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science. Photo credit: NASA/Kim Shiflett

  6. KSC-2009-2045

    NASA Image and Video Library

    2009-03-15

    CAPE CANAVERAL, Fla. – In the Operations and Checkout Building at NASA's Kennedy Space Center in Florida, STS-119 Mission Specialist Steve Swanson completes putting on the launch-and-entry suit, with the helmet, for the launch of space shuttle Discovery. The crew will be heading for Launch Pad 39A and liftoff of Discovery, scheduled for 7:43 p.m. EDT on March 15. An earlier launch attempt March 11 was scrubbed at 2:36 p.m. due to a gaseous hydrogen leak from the external tank at the Ground Umbilical Carrier Plate during tanking. A seven-inch quick disconnect and two seals were replaced. The STS-119 mission is the 28th to the International Space Station and the 125th space shuttle flight. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science. Photo credit: NASA/Kim Shiflett

  7. STS117-S-029

    NASA Image and Video Library

    2007-06-08

    STS117-S-029 (8 June 2007) --- The drifting smoke plumes from the launch of Space Shuttle Atlantis (out of frame) swirl above the Vehicle Assembly Building near sunset. Atlantis and its seven-member STS-117 crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  8. STS117-S-014

    NASA Image and Video Library

    2007-06-08

    STS117-S-014 (8 June 2007) --- Through the large windows in the Launch Control Center, NASA officials watch the launch of Space Shuttle Atlantis on mission STS-117. Atlantis and its seven-member crew head toward Earth-orbit and a scheduled link-up with the International Space Station. Liftoff from Kennedy Space Center's launch pad 39A occurred at 7:38 p.m. (EDT) on June 8, 2007. Onboard are astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Patrick Forrester, John "Danny" Olivas, Steven Swanson and Clayton Anderson, all mission specialists. Anderson will join Expedition 15 in progress to serve as a flight engineer aboard the station. Atlantis will dock with the orbital outpost on Sunday, June 10, to begin a joint mission that will increase the complex's power generation capability. Using the shuttle and station robotic arms and conducting three scheduled spacewalks, the astronauts will install another set of giant solar array wings on the station and retract another array, preparing it for a future move.

  9. KSC-2009-2402

    NASA Image and Video Library

    2009-03-28

    CAPE CANAVERAL, Fla. – With space shuttle Discovery as backdrop on Runway 15 at NASA's Kennedy Space Center in Florida, members of the STS-119 crew address the workers and guests on hand to welcome them home following their 13-day, 5.3-million mile journey on the STS-119 mission to the International Space Station. From left are Commander Lee Archambault, Pilot Tony Antonelli and Mission Specialists Joseph Acaba, Steve Swanson, Richard Arnold and John Phillips. Main gear touchdown was at 3:13:17 p.m. EDT. Nose gear touchdown was at 3:13:40 p.m. and wheels stop was at 3:14:45 p.m. Discovery delivered the final pair of large power-generating solar array wings and the S6 truss segment. The mission was the 28th flight to the station, the 36th flight of Discovery and the 125th in the Space Shuttle Program, as well as the 70th landing at Kennedy. Photo credit: NASA/Kim Shiflett

  10. Balancing dual roles in end-of-life research.

    PubMed

    Martin, Wanda; Grey, Meredith; Webber, Terry; Robinson, Linnea; Hartt, Nancy; Cairns, Moira; Stajduhar, Kelli

    2007-01-01

    Ethical and practical issues are sure to arise from the majority of research studies done with palliative populations. Whether it is feeling opportunistic, being emotionally available, or struggling with witnessing a gap in service and needs of the participants receiving care, nurses involved in research find a way to balance both roles to meet the needs of the participants as well as the study (McIlfatrick, Sullivan, & McKenna, 2006). This paper highlights some of the practical and ethical issues that arise when frontline nurses also take on the role of research assistant for studies with palliative populations. Specifically, the authors highlight their personal experiences based on their research assistant work on a study examining family caregiver coping in end-of-life cancer care. The authors discuss the "balancing act" of taking on these dual roles and offer recommendations on how to be with and approach people when doing research at the end of life using a framework based on Swanson's Theory of Caring (1991).

  11. Methylphenidate DAT binding in adolescents with Attention-Deficit/ Hyperactivity Disorder comorbid with Substance Use Disorder--a single photon emission computed tomography with [Tc(99m)]TRODAT-1 study.

    PubMed

    Szobot, Claudia M; Shih, Ming Chi; Schaefer, Thais; Júnior, Neivo; Hoexter, Marcelo Q; Fu, Ying Kai; Pechansky, Flávio; Bressan, Rodrigo A; Rohde, Luis A P

    2008-04-15

    Attention-Deficit/Hyperactivity Disorder (ADHD) is highly prevalent among adolescents with Substance Use Disorders (SUD). Effects of methylphenidate (MPH) on ADHD are attributed to its properties of blocking the dopamine transporter (DAT) in the striatum. However, it has been demonstrated that drug addiction is associated with dopaminergic system changes that may affect MPH brain effects, emphasizing the need to better understand MPH actions in subjects with ADHD+SUD. To evaluate the effect of an extended release formulation of MPH (MPH-SODAS) on DAT availability in 17 stimulant-naive ADHD adolescents with comorbid SUD (cannabis and cocaine). Subjects underwent two single photon emission computed tomography (SPECT) scans with [Tc(99m)]TRODAT-1, at baseline and after 3 weeks on MPH-SODAS. Clinical assessment for ADHD relied on the Swanson, Nolan and Pelham Scale - version IV (SNAP-IV). Caudate and putamen DAT binding potential (BP) was calculated. After 3 weeks on MPH-SODAS, there was a significant reduction of SNAP-IV total scores (p<0.001), and approximately 52% reductions of DAT BP at the left and right caudate. Similar decreases were found at the left and right putamen (p<0.001 for all analyses). This study shows that the magnitude of DAT blockade induced by MPH in this population is similar to what is found in ADHD patients without SUD comorbidity, providing neurobiological support for trials with stimulants in adolescents with ADHD+SUD, an important population excluded from studies.

  12. Efficacy and Safety Extrapolation Analyses for Atomoxetine in Young Children with Attention-Deficit/Hyperactivity Disorder.

    PubMed

    Upadhyaya, Himanshu; Kratochvil, Christopher; Ghuman, Jaswinder; Camporeale, Angelo; Lipsius, Sarah; D'Souza, Deborah; Tanaka, Yoko

    2015-12-01

    This extrapolation analysis qualitatively compared the efficacy and safety profile of atomoxetine from Lilly clinical trial data in 6-7-year-old patients with attention-deficit/hyperactivity disorder (ADHD) with that of published literature in 4-5-year-old patients with ADHD (two open-label [4-5-year-old patients] and one placebo-controlled study [5-year-old patients]). The main efficacy analyses included placebo-controlled Lilly data and the placebo-controlled external study (5-year-old patients) data. The primary efficacy variables used in these studies were the ADHD Rating Scale-IV Parent Version, Investigator Administered (ADHD-RS-IV-Parent:Inv) total score, or the Swanson, Nolan and Pelham (SNAP-IV) scale score. Safety analyses included treatment-emergent adverse events (TEAEs) and vital signs. Descriptive statistics (means, percentages) are presented. Acute atomoxetine treatment improved core ADHD symptoms in both 6-7-year-old patients (n=565) and 5-year-old patients (n=37) (treatment effect: -10.16 and -7.42). In an analysis of placebo-controlled groups, the mean duration of exposure to atomoxetine was ∼ 7 weeks for 6-7-year-old patients and 9 weeks for 5-year-old patients. Decreased appetite was the most common TEAE in atomoxetine-treated patients. The TEAEs observed at a higher rate in 5-year-old versus 6-7-year-old patients were irritability (36.8% vs. 3.6%) and other mood-related events (6.9% each vs. <3.0%). Blood pressure and pulse increased in both 4-5-year-old patients and 6-7-year-old patients, whereas a weight increase was seen only in the 6-7-year-old patients. Although limited by the small sample size of the external studies, these analyses suggest that in 5-year-old patients with ADHD, atomoxetine may improve ADHD symptoms, but possibly to a lesser extent than in older children, with some adverse events occurring at a higher rate in 5-year-old patients.

  13. More on the decoder error probability for Reed-Solomon codes

    NASA Technical Reports Server (NTRS)

    Cheung, K.-M.

    1987-01-01

    The decoder error probability for Reed-Solomon codes (more generally, linear maximum distance separable codes) is examined. McEliece and Swanson offered an upper bound on P sub E (u), the decoder error probability given that u symbol errors occurs. This upper bound is slightly greater than Q, the probability that a completely random error pattern will cause decoder error. By using a combinatoric technique, the principle of inclusion and exclusion, an exact formula for P sub E (u) is derived. The P sub e (u) for the (255, 223) Reed-Solomon Code used by NASA, and for the (31,15) Reed-Solomon code (JTIDS code), are calculated using the exact formula, and the P sub E (u)'s are observed to approach the Q's of the codes rapidly as u gets larger. An upper bound for the expression is derived, and is shown to decrease nearly exponentially as u increases. This proves analytically that P sub E (u) indeed approaches Q as u becomes large, and some laws of large numbers come into play.

  14. A sampling and classification item selection approach with content balancing.

    PubMed

    Chen, Pei-Hua

    2015-03-01

    Existing automated test assembly methods typically employ constrained combinatorial optimization. Constructing forms sequentially based on an optimization approach usually results in unparallel forms and requires heuristic modifications. Methods based on a random search approach have the major advantage of producing parallel forms sequentially without further adjustment. This study incorporated a flexible content-balancing element into the statistical perspective item selection method of the cell-only method (Chen et al. in Educational and Psychological Measurement, 72(6), 933-953, 2012). The new method was compared with a sequential interitem distance weighted deviation model (IID WDM) (Swanson & Stocking in Applied Psychological Measurement, 17(2), 151-166, 1993), a simultaneous IID WDM, and a big-shadow-test mixed integer programming (BST MIP) method to construct multiple parallel forms based on matching a reference form item-by-item. The results showed that the cell-only method with content balancing and the sequential and simultaneous versions of IID WDM yielded results comparable to those obtained using the BST MIP method. The cell-only method with content balancing is computationally less intensive than the sequential and simultaneous versions of IID WDM.

  15. Effects of prenatal marijuana exposure on child behavior problems at age 10.

    PubMed

    Goldschmidt, L; Day, N L; Richardson, G A

    2000-01-01

    This is a prospective study of the effects of prenatal marijuana exposure on child behavior problems at age 10. The sample consisted of low-income women attending a prenatal clinic. Half of the women were African-American and half were Caucasian. The majority of the women decreased their use of marijuana during pregnancy. The assessments of child behavior problems included the Child Behavior Checklist (CBCL), Teacher's Report Form (TRF), and the Swanson, Noland, and Pelham (SNAP) checklist. Multiple and logistic regressions were employed to analyze the relations between marijuana use and behavior problems of the children, while controlling for the effects of other extraneous variables. Prenatal marijuana use was significantly related to increased hyperactivity, impulsivity, and inattention symptoms as measured by the SNAP, increased delinquency as measured by the CBCL, and increased delinquency and externalizing problems as measured by the TRF. The pathway between prenatal marijuana exposure and delinquency was mediated by the effects of marijuana exposure on inattention symptoms. These findings indicate that prenatal marijuana exposure has an effect on child behavior problems at age 10.

  16. Development and validation of the Parents' Perceived Self-Efficacy to Manage Children's Internet Use Scale for parents of adolescents with attention-deficit/hyperactivity disorder.

    PubMed

    Hsieh, Yi-Ping; Chou, Wen-Jiun; Wang, Peng-Wei; Yen, Cheng-Fang

    2017-12-01

    Background and aims This study developed and validated the Parents' Perceived Self-Efficacy to Manage Children's Internet Use Scale (PSMIS) in the parents of children with attention-deficit/hyperactivity disorder (ADHD). Methods In total, 231 parents of children with ADHD were invited to complete the PSMIS, followed by the Chen Internet Addiction Scale and the short version of Swanson, Nolan, and Pelham, Version IV Scale - Chinese version for analyzing Internet addiction severity and ADHD symptoms, respectively. Results The results of exploratory and confirmatory factor analyses confirmed the four-factor structure of the 18-item PSMIS. The significant difference in the levels of parents' perceived self-efficacy between the parents of children with and without Internet addiction supported the criterion-related validity of the PSMIS. The internal consistency and 1-month test-retest reliability were acceptable. Conclusion The results indicate that the PSMIS has acceptable validity and reliability and can be used for measuring parents' perceived self-efficacy to manage children's Internet use among parents of children with ADHD.

  17. Reconnaissance for radioactive deposits in the vicinity of Teller and Cape Nome, Seward Peninsula, Alaska, 1946-47

    USGS Publications Warehouse

    White, Max Gregg; West, W.S.; Matzko, J.J.

    1953-01-01

    Placer-mining areas and bedrock exposures near Teller on the Seward Peninsula, Alaska, were investigated in June and July, 1946, for possible sources of radioactive materials. The areas that were investigated are: Dese Creek, southeast of Teller; Bluestone River basin, south and southeast of Teller; Sunset Creek and other small streams flowing south into Grantley Harbor, northeast of Teller; and, also northeast of Teller, Swanson Creek and its tributaries, which flow north into the Agiapuk River basin. No significant amount of radioactive material was found, either in the stream gravels or in the bedrock of any of the areas. A heavy-mineral fraction obtained from a granite boulder probably derived from a bench gravel on Gold Run contains 0. 017 percent equivalent uranium, but the radioactivity is due to allanite and zircon. The types of bedrock tested include schist, slate, and greenstone. Readings on fresh surfaces of rock were the same as, or only slightly above the background count. The maximum radioactivity in stream concentrates is 0. 004 percent equivalent uranium in a sluice concentrate from Sunset Creek.

  18. Anhydrite in the 1989 1990 lavas and xenoliths from Redoubt Volcano, Alaska

    NASA Astrophysics Data System (ADS)

    Swanson, S. E.; Kearney, C. S.

    2008-08-01

    The eruption of Redoubt Volcano in Alaska produced a moderate sulfur emission (estimated at 1 × 10 tons SO 2), but relatively small volume of lava (0.11 km ) with pre-eruption estimates of 840-950 °C and fO 21.5 to 2.0 log units above NNO (Swanson, S.E., Nye, C.J., Miller, T.P., Avery, V.F., 1994. Magma mixing in the 1989-1990 eruption of Redoubt Volcano: Part II. Evidence from mineral and glass chemistry. Journal of Volcanology and Geothermal Research 62, 453-468). Petrologic estimates of sulfur production (Sigurdsson, H., Devine, J.D.,Davis, A.N., 1985. The petrologic estimation of volcanic degassing. Jokull 35, 1-8) from this eruption (Gerlach, T., Westrich, H.R., Casadevall, T.J., Finnegan, D.L., 1994. Vapor Saturation and accumulation in magmas of the 1989-1990 eruption of Redoubt Volcano, Alaska. Journal of Volcanology and Geothermal Research 62, 317-337) are considerably less than the measured sulfur emission, leading workers to propose the existence of a pre-eruption vapor phase to explain the "excess" sulfur. Initial examination of the 1989-1990 Redoubt eruptive products reported anhydrite (Nye, C.J., Swanson, S.E., Avery, V.F., Miller, T.P., 1994. Geochemistry of the 1989-1990 eruption of Redoubt Volcano: Part I, whole-rock, major- and trace-element chemistry. Journal of Volcanology and Geothermal Research 62, 429-452.) in interstitial glass from some cognate gabbroic xenoliths, but anhydrite was not noted in any of the andesites. A Boeing 747 encountered the ash plume from the initial eruptive phase on December 15, 1989 and provided ash samples that reportedly contained gypsum (Bayhurst, G.K., Wohletz, K.H., Mason, A.S., 1994. A method for characterizing volcanic ash from the December 15, 1989, eruption of Redoubt Volcano, Alaska. U.S. Geological Survey Bulletin 2047, 13-17). However, the identification was based on EDS analyses on a SEM and the mineral could have been anhydrite. Reexamination of the 1989-1990 Redoubt lavas and xenoliths revealed the presence of rare, fine-grained (10s of microns) anhydrite crystals in the lavas and larger (10s to 100s of microns) crystals in the xenoliths. The anhydrite forms elongate crystals with sharp contacts against the groundmass glass. Grains show rounded terminations suggesting breakdown of the anhydrite, perhaps during eruption. The anhydrite is a sparse phase in the lavas, but occurs in lavas and cognate xenoliths erupted throughout the eruption. The presence and breakdown of anhydrite may explain the "excess" sulfur associated with the Redoubt eruption. A careful search of other freshly erupted andesitic lavas solidified from hydrous, oxidizing magmas should reveal other examples of anhydrite and cause a rethinking of the source of sulfur in volcanic emissions.

  19. Veggie Hardware Validation Test Preliminary Results and Lessons Learned

    NASA Technical Reports Server (NTRS)

    Massa, Gioia D.; Dufour, Nicole F.; Smith, T. M.

    2014-01-01

    The Veggie hardware validation test, VEG-01, was conducted on the International Space Station during Expeditions 39 and 40 from May through June of 2014. The Veggie hardware and the VEG-01 experiment payload were launched to station aboard the SpaceX-3 resupply mission in April, 2014. Veggie was installed in an Expedite-the-Processing-of-Experiments-to-Space-Station (ExPRESS) rack in the Columbus module, and the VEG-01 validation test was initiated. Veggie installation was successful, and power was supplied to the unit. The hardware was programmed and the root mat reservoir and plant pillows were installed without issue. As expected, a small amount of growth media was observed in the sealed bags which enclosed the plant pillows when they were destowed. Astronaut Steve Swanson used the wet/dry vacuum to clean up the escaped particles. Water insertion or priming the first plant pillow was unsuccessful as an issue prevented water movement through the quick disconnect. All subsequent pillows were successfully primed, and the initial pillow was replaced with a backup pillow and successfully primed. Six pillows were primed, but only five pillows had plants which germinated. After about a week and a half it was observed that plants were not growing well and that pillow wicks were dry. This indicated that the reservoir was not supplying sufficient water to the pillows via wicking, and so the team reverted to an operational fix which added water directly to the plant pillows. Direct watering of the pillows led to a recovery in several of the stressed plants; a couple of which did not recover. An important lesson learned involved Veggie's bellows. The bellows tended to float and interfere with operations when opened, so Steve secured them to the baseplate during plant tending operations. Due to the perceived intensity of the LED lights, the crew found it challenging to both work under the lights and read crew procedures on their computer. Although the lights are not a safety hazard, for visual comfort crewmembers were advised to wear sunglasses when working with the plants and then they can lift glasses to read procedures. Steve Swanson had already trail-blazed this procedure when he initiated VEG-01. The temperature and humidity data logger was relocated mid-experiment to provide measurements on both sides of the unit. Images of the plants were downlinked weekly, and videos of installation and harvest were recorded. This imaging frequency was not sufficient to monitor and respond to changes in plant growth. Plants, samples, and data loggers will be returned on SpaceX-4, scheduled to return the fall of 2014. Lessons learned will be translated into hardware and operational modifications for future Veggie payloads.

  20. Flowfield Analysis of a Small Entry Probe (SPRITE) Tested in an Arc Jet

    NASA Technical Reports Server (NTRS)

    Prabhu, Dinesh K.

    2012-01-01

    A novel concept of small size (diameter less than 15 inches) entry probes named SPRITE (Small Probe Re-entry Investigation for TPS Engineering) has been developed at NASA Ames Research Center (ARC). These flight probes have on-board data acquisition systems that have also been developed in parallel at NASA ARC by Greg Swanson1. Flight probes of this size facilitate testing over a wide range of conditions in arc jets available at NASA ARC, thereby fulfilling a 'test what you fly' paradigm. As indicated by the acronym, these probes, with suitably tailored trajectories, are primarily meant to be robotic flight test beds for TPS materials, although the design is flexible enough to accommodate additional objectives of flight-testing other vehicle subsystems. A first step towards establishing the feasibility of the SPRITE concept is to arc-jet test fully instrumented models at flight scale. In a follow-on to the Large-Scale Article Tests (LSAT2) performed in the 60 MW Interaction Heating Facility (IHF) in late 2008/early 2009, a full-scale model of Deep Space-2 (DS23) made of red oak was tested in the 20 MW Aerodynamic Heating Facility (AHF). There were no issues with mass capture by the diffuser for blunt bodies of roughly 15 inches diameter tested in the 18-inch nozzle of the AHF. Building on this initial success, two identical test articles - SPRITE-T1-1 and SPRITE-T1-2 (T1 indicating the choice of back shell geometry) - were fabricated, and one of them, SPRITE-T1-1, was tested in the AHF recently. Both these test articles, 14 inches in diameter, have a 45deg sphere-cone (like DS2) made of PICA bonded on to a 1/8th inch thick aluminum shell using RTV. The aft portion of the test article is a conical frustum (15deg cone angle) with LI-2200 bonded on to the aluminum shell. Each model is fully instrumented with: (a) thermocouples imbedded in plugs in the heat shield, (b) thermocouples bonded to the aluminum substructure; the thermocouples are distributed over the entire shell, and (c) a few strain gages. Data from some of the thermocouples and gages are acquired by the on-board data acquisition system (DAS), while data from the others are routed to the facility-provided DAS, thereby enabling a cross check on the in situ measurement capability. as inputs to v2.6.1 of the in-house materials thermal response code, FIAT

  1. Potential role of pre- and postnatal testosterone levels in attention-deficit/hyperactivity disorder: is there a sex difference?

    PubMed

    Wang, Liang-Jen; Chou, Miao-Chun; Chou, Wen-Jiun; Lee, Min-Jing; Lee, Sheng-Yu; Lin, Pao-Yen; Lee, Yi-Hsuan; Yang, Yi-Hsin; Yen, Cheng-Fang

    2017-01-01

    Both prenatal testosterone (T) exposure and postnatal T levels have been associated with developing neural circuitry and behavioral systems. This study examined the potential correlation between pre- and postnatal T levels and behavioral and neurocognitive profiles of children with attention-deficit/hyperactivity disorder (ADHD). Two hundred ADHD patients with a mean age of 8.7±2.0 years (158 boys and 42 girls) were recruited. The ratio of the length of the right index finger (2D) to that of the right ring finger (4D) (2D/4D ratio) served as a surrogate of prenatal T exposure, and postnatal T was determined using salivary T concentration. Behavioral symptoms were evaluated using the Swanson, Nolan, and Pelham - Version IV Scale for ADHD (SNAP-IV). Neurocognitive function was assessed using the Wechsler Intelligence Scale for Children - Fourth Edition (WISC-IV) and Conners' Continuous Performance Test (CPT). Lower 2D/4D ratios were associated with comorbid disruptive behavior disorders ( t =2.15, P =0.033) in all participants. Among the boys with ADHD, neither 2D/4D ratios nor salivary T levels were associated with behavioral symptoms or neurocognitive function. Among the girls with ADHD, the salivary T level was positively correlated with the Perceptual Reasoning Index of the WISC-IV ( r =0.48, P =0.001) and the Confidence Index ( r =0.37, P =0.017) and Omission Errors of the CPT ( r =0.62, P <0.001). Findings suggest that a higher prenatal T exposure is associated with a greater risk of developing disruptive behavior disorders, and T may exert differential neurocognitive effects between boys and girls with ADHD. However, the neurobiological mechanisms of T involved in the pathogenesis of ADHD warrant further investigation.

  2. A self-consistent phase-field approach to implicit solvation of charged molecules with Poisson-Boltzmann electrostatics

    NASA Astrophysics Data System (ADS)

    Sun, Hui; Wen, Jiayi; Zhao, Yanxiang; Li, Bo; McCammon, J. Andrew

    2015-12-01

    Dielectric boundary based implicit-solvent models provide efficient descriptions of coarse-grained effects, particularly the electrostatic effect, of aqueous solvent. Recent years have seen the initial success of a new such model, variational implicit-solvent model (VISM) [Dzubiella, Swanson, and McCammon Phys. Rev. Lett. 96, 087802 (2006) and J. Chem. Phys. 124, 084905 (2006)], in capturing multiple dry and wet hydration states, describing the subtle electrostatic effect in hydrophobic interactions, and providing qualitatively good estimates of solvation free energies. Here, we develop a phase-field VISM to the solvation of charged molecules in aqueous solvent to include more flexibility. In this approach, a stable equilibrium molecular system is described by a phase field that takes one constant value in the solute region and a different constant value in the solvent region, and smoothly changes its value on a thin transition layer representing a smeared solute-solvent interface or dielectric boundary. Such a phase field minimizes an effective solvation free-energy functional that consists of the solute-solvent interfacial energy, solute-solvent van der Waals interaction energy, and electrostatic free energy described by the Poisson-Boltzmann theory. We apply our model and methods to the solvation of single ions, two parallel plates, and protein complexes BphC and p53/MDM2 to demonstrate the capability and efficiency of our approach at different levels. With a diffuse dielectric boundary, our new approach can describe the dielectric asymmetry in the solute-solvent interfacial region. Our theory is developed based on rigorous mathematical studies and is also connected to the Lum-Chandler-Weeks theory (1999). We discuss these connections and possible extensions of our theory and methods.

  3. A self-consistent phase-field approach to implicit solvation of charged molecules with Poisson-Boltzmann electrostatics.

    PubMed

    Sun, Hui; Wen, Jiayi; Zhao, Yanxiang; Li, Bo; McCammon, J Andrew

    2015-12-28

    Dielectric boundary based implicit-solvent models provide efficient descriptions of coarse-grained effects, particularly the electrostatic effect, of aqueous solvent. Recent years have seen the initial success of a new such model, variational implicit-solvent model (VISM) [Dzubiella, Swanson, and McCammon Phys. Rev. Lett. 96, 087802 (2006) and J. Chem. Phys. 124, 084905 (2006)], in capturing multiple dry and wet hydration states, describing the subtle electrostatic effect in hydrophobic interactions, and providing qualitatively good estimates of solvation free energies. Here, we develop a phase-field VISM to the solvation of charged molecules in aqueous solvent to include more flexibility. In this approach, a stable equilibrium molecular system is described by a phase field that takes one constant value in the solute region and a different constant value in the solvent region, and smoothly changes its value on a thin transition layer representing a smeared solute-solvent interface or dielectric boundary. Such a phase field minimizes an effective solvation free-energy functional that consists of the solute-solvent interfacial energy, solute-solvent van der Waals interaction energy, and electrostatic free energy described by the Poisson-Boltzmann theory. We apply our model and methods to the solvation of single ions, two parallel plates, and protein complexes BphC and p53/MDM2 to demonstrate the capability and efficiency of our approach at different levels. With a diffuse dielectric boundary, our new approach can describe the dielectric asymmetry in the solute-solvent interfacial region. Our theory is developed based on rigorous mathematical studies and is also connected to the Lum-Chandler-Weeks theory (1999). We discuss these connections and possible extensions of our theory and methods.

  4. A self-consistent phase-field approach to implicit solvation of charged molecules with Poisson–Boltzmann electrostatics

    PubMed Central

    Sun, Hui; Wen, Jiayi; Zhao, Yanxiang; Li, Bo; McCammon, J. Andrew

    2015-01-01

    Dielectric boundary based implicit-solvent models provide efficient descriptions of coarse-grained effects, particularly the electrostatic effect, of aqueous solvent. Recent years have seen the initial success of a new such model, variational implicit-solvent model (VISM) [Dzubiella, Swanson, and McCammon Phys. Rev. Lett. 96, 087802 (2006) and J. Chem. Phys. 124, 084905 (2006)], in capturing multiple dry and wet hydration states, describing the subtle electrostatic effect in hydrophobic interactions, and providing qualitatively good estimates of solvation free energies. Here, we develop a phase-field VISM to the solvation of charged molecules in aqueous solvent to include more flexibility. In this approach, a stable equilibrium molecular system is described by a phase field that takes one constant value in the solute region and a different constant value in the solvent region, and smoothly changes its value on a thin transition layer representing a smeared solute-solvent interface or dielectric boundary. Such a phase field minimizes an effective solvation free-energy functional that consists of the solute-solvent interfacial energy, solute-solvent van der Waals interaction energy, and electrostatic free energy described by the Poisson–Boltzmann theory. We apply our model and methods to the solvation of single ions, two parallel plates, and protein complexes BphC and p53/MDM2 to demonstrate the capability and efficiency of our approach at different levels. With a diffuse dielectric boundary, our new approach can describe the dielectric asymmetry in the solute-solvent interfacial region. Our theory is developed based on rigorous mathematical studies and is also connected to the Lum–Chandler–Weeks theory (1999). We discuss these connections and possible extensions of our theory and methods. PMID:26723595

  5. Association Between Changes in Caregiver Depressive Symptoms and Child Attention-Deficit/Hyperactivity Disorder Symptoms.

    PubMed

    Walls, Morgan; Cabral, Howard; Feinberg, Emily; Silverstein, Michael

    2018-06-01

    Depression is highly prevalent among caregivers of children with attention-deficit/hyperactivity disorder (ADHD). We examined the association between caregiver depressive symptom trajectories and changes in child ADHD symptoms. We analyzed data from a randomized trial of 2 ADHD care management systems for children aged 6 to 12 years and their caregivers (n = 156 dyads). Child ADHD symptoms were measured using the Swanson, Nolan, and Pelham rating scale (SNAP-IV). Caregiver depressive symptoms were measured using the Quick Inventory of Depressive Symptomatology (QIDS). Measures were assessed at baseline, 6 months, and 12 months. We used multivariable models to examine associations between changes in caregiver depressive symptoms and changes in child ADHD symptoms. From baseline to 12 months, children of caregivers with improved depressive symptoms had significantly greater reductions in SNAP-IV scores (change score: -1.43) compared with those whose depressive symptoms did not change (change score: -0.97) or worsened (change score: -0.23, p = 0.003). In adjusted models, improved caregiver depressive symptoms were associated with greater reductions in SNAP-IV scores over the 12-month period. Compared with those with worsening caregiver depressive symptoms, children whose caregivers showed no significant changes in depressive symptoms had a -0.78 point (95% confidence interval [CI]: -1.40 to -0.17) greater reduction in the SNAP-IV score, and those children whose caregiver depressive symptoms improved had a -1.31 point greater reduction in the SNAP-IV score (95% CI: -1.97 to -0.66). Given the longitudinal association between caregiver depressive symptom and child ADHD symptom trajectories, interventions that address the behavioral health needs of the family unit may offer promise for urban children with ADHD.

  6. Parental quality of life and depressive mood following methylphenidate treatment of children with attention-deficit hyperactivity disorder.

    PubMed

    Kim, Yeni; Kim, Bongseog; Chang, Jae-Seung; Kim, Bung-Nyun; Cho, Soo-Churl; Hwang, Jun-Won

    2014-07-01

    This naturalistic study investigated the associations between quality of life and depressive mood in parents and symptom changes in attention-deficit hyperactivity disorder (ADHD) children. At baseline and at weeks 4 and 8, the parents evaluated their children, who were receiving treatment with osmotic-release oral system methylphenidate (mean dosage 36.3 ± 15.5 mg/day), using the Swanson, Nolan, and Pelham - Fourth Edition (SNAP-IV-18) scale. The parents evaluated themselves using the Beck Depression Inventory (BDI) and the World Health Organization Quality of Life Assessment, Brief Version (WHOQOL-BREF). A significant reduction in SNAP-IV-18 scores and improvements in parental BDI scores and parental WHOQOL-BREF scores were observed. The decrease in BDI scores from baseline to 8 weeks was significantly associated with increases in WHOQOL-BREF sub-domain scores from baseline to 8 weeks, with a greater decrease at 4 weeks and after. The decrease in the SNAP-IV-18 hyperactivity-impulsivity score was significantly associated with increases in WHOQOL social sub-domain scores from baseline to 8 weeks. For those patients who showed a 25% or greater decrease in the SNAP-IV-18 total scores from baseline to 8 weeks, the decreases in the SNAP-IV-18 total score and in the inattention and hyperactivity-impulsivity scores were significantly associated with a decrease in BDI scores from baseline to 8 weeks. Methylphenidate treatment for ADHD was associated with both symptom alleviation in children with ADHD and improvement in parental depressive mood and quality of life, suggesting that the effects of treatment could go beyond symptom improvement in ADHD. © 2014 The Authors. Psychiatry and Clinical Neurosciences © 2014 Japanese Society of Psychiatry and Neurology.

  7. An analytic model for acoustic scattering from an impedance cylinder placed normal to an impedance plane

    NASA Astrophysics Data System (ADS)

    Swearingen, Michelle E.

    2004-04-01

    An analytic model, developed in cylindrical coordinates, is described for the scattering of a spherical wave off a semi-infinite reight cylinder placed normal to a ground surface. The motivation for the research is to have a model with which one can simulate scattering from a single tree and which can be used as a fundamental element in a model for estimating the attenuation in a forest comprised of multiple tree trunks. Comparisons are made to the plane wave case, the transparent cylinder case, and the rigid and soft ground cases as a method of theoretically verifying the model for the contemplated range of model parameters. Agreement is regarded as excellent for these benchmark cases. Model sensitivity to five parameters is also explored. An experiment was performed to study the scattering from a cylinder normal to a ground surface. The data from the experiment is analyzed with a transfer function method to yield frequency and impulse responses, and calculations based on the analytic model are compared to the experimental data. Thesis advisor: David C. Swanson Copies of this thesis written in English can be obtained from

  8. Symptoms Associated With Attention Deficit/Hyperactivity Disorder and Autism Spectrum Disorders in School-Aged Children Prenatally Exposed to Substances

    PubMed Central

    Sandtorv, Lisbeth Beate; Fevang, Silje Katrine Elgen; Nilsen, Sondre Aasen; Bøe, Tormod; Gjestad, Rolf; Haugland, Siren; Elgen, Irene Bircow

    2018-01-01

    Prenatal exposure to substances may influence a child’s neurodevelopment and impact on subsequent mental health. In a hospital-based population of school-aged children prenatally exposed to opiates and a number of illicit substances (n = 57), we evaluated mental health symptoms associated with attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorders (ASD) using the Swanson, Nolan, and Pelham Questionnaire, revision IV (SNAP-IV) and the Autism Spectrum Screening Questionnaire (ASSQ) and compared the scores to a reference group which comprised children from the population-based Bergen Child Study (n = 171). Prenatally exposed children had significantly higher SNAP-IV scores associated with ADHD symptoms in both areas of inattention and hyperactivity/impulsivity and also reported a higher ASSQ score related to an increased number of symptoms associated with ASD, compared with the reference group. Of tested predictors of mental health outcomes in the exposed group, the intelligence quotient was a strong predictor of most mental health outcomes, and neonatal abstinence syndrome was a predictor of inattention. In conclusion, prenatally exposed children had more mental health symptoms associated with ADHD and ASD, compared with the reference group. PMID:29618930

  9. KSC-2009-2049

    NASA Image and Video Library

    2009-03-15

    CAPE CANAVERAL, Fla. – The STS-119 crew members pause for photos before boarding the Astrovan to take them to Launch Pad 39A at NASA's Kennedy Space Center in Florida for launch of space shuttle Discovery to the International Space Station. From left are Mission Specialists Koichi Wakata, John Phillips, Richard Arnold, Steve Swanson and Joseph Acaba, Pilot Tony Antonelli and Commander Lee Archambault. Wakata represents the Japan Aerospace Exploration Agency and will remain on the International Space Station, replacing Expedition 18 Flight Engineer Sandra Magnus, who returns to Earth with the STS-119 crew. Liftoff of Discovery is scheduled for 7:43 p.m. EDT on March 15. An earlier launch attempt March 11 was scrubbed at 2:36 p.m. due to a gaseous hydrogen leak from the external tank at the Ground Umbilical Carrier Plate during tanking. A seven-inch quick disconnect and two seals were replaced. The STS-119 mission is the 28th to the space station and the 125th space shuttle flight. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science. Photo credit: NASA/Kim Shiflett

  10. KSC-2009-2032

    NASA Image and Video Library

    2009-03-15

    CAPE CANAVERAL, Fla. – Honoring tradition, the crew of space shuttle Discovery's STS-119 mission pose for a photo at the breakfast table at NASA's Kennedy Space Center in Florida. From left are Mission Specialists Steve Swanson, Joseph Acaba, Pilot Tony Antonelli, Commander Lee Archambault, and Mission Specialists John Phillips, Richard Arnold and Koichi Wakata, who represents the Japan Aerospace Exploration Agency. Following the meal, the crew members will put on their launch-and-entry suits and head for Launch Pad 39A. An earlier launch attempt March 11 was scrubbed at 2:36 p.m. due to a gaseous hydrogen leak from the external tank at the Ground Umbilical Carrier Plate during tanking. A seven-inch quick disconnect and two seals were replaced. The STS-119 mission is the 28th to the International Space Station and the 125th space shuttle flight. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science. Liftoff of Discovery is scheduled for 7:43 p.m. EDT on March 15. Photo credit: NASA/Jack Pfaller

  11. Environmental health and nursing: piloting a technology-enhanced distance learning module.

    PubMed

    Olson, Debra; Stedman-Smith, Maggie; Fredrickson, Ann

    2005-08-01

    The results of a pilot study evaluating a technology-enhanced distance learning module to impart environmental health core concepts to nurses are presented in this article. The internet-based module was developed for continuing professional education and imparts principles of adult education through interactive features including simulated clinical vignettes, an environmental justice case study, and hyperlinks to websites related to environmental protection and health regulation. Mean gains between pre- and post-tests; participant identification of adult learning principles as advanced by Knowles, Holton, and Swanson (1998); and satisfaction were measured among participating RNs (N = 34). A 6% mean gain in learning occurred between pre- and post-tests (95% CI .51 to 1.37, p < .0001). No significant differences in learning occurred for those who prefer face-to-face instruction and those who tend to procrastinate. Ninety-four percent of respondents indicated they were satisfied or very satisfied with the module. A strong association was found between recognition of adult learning principles as enhancing the assimilation of knowledge and competencies of environmental health and high satisfaction with the module. Distance learning via the Internet shows promise as a format to promote environmental health education for nurses.

  12. Should there be separate parent and teacher-based categories of ODD? Evidence from a general population.

    PubMed

    Munkvold, Linda; Lundervold, Astri; Lie, Stein Atle; Manger, Terje

    2009-10-01

    To examine the occurrence of oppositional defiant disorder (ODD) symptoms in a general population of boys and girls, as reported by parents and teachers, and to investigate differences in prevalence estimates, depending on how parents' and teachers' ratings were combined. Data were collected from 7007 children (aged 7-9) who participated in The Bergen Child Study (BCS), an ongoing population-based study of children's development and mental health. ODD symptoms were measured by the SNAP-IV (Swanson, Nolan, & Pelham-IV) Oppositional Defiant Disorder sub-scale (SNAP-IV ODD) that was distributed to parents and teachers. Co-occurring symptoms of mental health problems were measured by the Strengths and Difficulties Questionnaire (SDQ). Prevalence-estimates of ODD varied considerably depending on how ratings from parents and teachers were combined. Specific ODD symptoms occurred at very different rates depending on the rater and on the gender of the child being rated. Parents and teachers co-identified very few children with ODD. ODD identified by only one informant was associated with high levels of comorbid mental health problems and impairment according to both informants. The results support an informant-specific conceptualization of childhood ODD.

  13. Frequency and correlates of suicidal ideation in pediatric obsessive-compulsive disorder.

    PubMed

    Storch, Eric A; Bussing, Regina; Jacob, Marni L; Nadeau, Joshua M; Crawford, Erika; Mutch, P Jane; Mason, Dana; Lewin, Adam B; Murphy, Tanya K

    2015-02-01

    This study examined the frequency and sociodemographic and clinical correlates of suicidal ideation in a sample of children and adolescents with obsessive-compulsive disorder (OCD). Fifty-four youth with OCD and their parent(s) were administered the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime, Children's Yale-Brown Obsessive Compulsive Scale, and Children's Depression Rating Scale-Revised. Children completed the Suicidal Ideation Questionnaire-Junior (SIQ-JR), Child Obsessive Compulsive Impact Scale-Child, and Multidimensional Anxiety Scale for Children; parents completed the Child Obsessive Compulsive Impact Scale-Parent, Swanson, Nolan, and Pelham-IV Parent Scale, and Young Mania Rating Scale-Parent Version. Seven youth endorsed clinically significant levels of suicidal ideation on the SIQ-JR. Suicidal ideation was significantly related to clinician-rated depressive symptoms, age, child-rated impairment and anxiety symptoms, and symmetry, sexuality/religiosity and miscellaneous symptom dimensions. There was no significant association between suicidal ideation and obsessive-compulsive symptom severity, comorbidity patterns, or several parent-rated indices (e.g., impairment, impulsivity). These results provide initial information regarding the frequency and correlates of suicidal ideation in treatment-seeking youth with OCD. Clinical implications are discussed, as well as directions for future research.

  14. STS-117 landing at Dryden

    NASA Image and Video Library

    2007-06-22

    STS117-S-047 (22 June 2007) --- Space Shuttle Atlantis' main landing gear touches down on runway 22 at NASA's Dryden Flight Research Center at Edwards Air Force Base in California concluding a successful assembly mission to the International Space Station. Atlantis landed on orbit 219 after 13 days, 20 hours and 12 minutes in space. The landing was diverted to California due to marginal weather at the Kennedy Space Center. Main gear touchdown was at 12:49:38 p.m. (PDT). Nose gear touchdown was at 12:49:49 p.m. and wheel stop was at 12:50:48 p.m. This was the 51st landing for the Space Shuttle Program at Edwards Air Force Base. The mission to the station was a success, installing and activating the S3/S4 truss and retracting the P6 arrays. Onboard were astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Steven Swanson, Patrick Forrester and John "Danny" Olivas, all STS-117 mission specialists. Also onboard was astronaut Sunita Williams, who was flight engineer on the Expedition 15 crew. She achieved a new milestone, a record-setting flight at 194 days, 18 hours and 58 minutes, the longest single spaceflight ever by a female astronaut or cosmonaut.

  15. STS-117 landing at Dryden

    NASA Image and Video Library

    2007-06-22

    STS117-S-049 (22 June 2007) --- Space Shuttle Atlantis' main landing gear touches down on runway 22 at NASA's Dryden Flight Research Center at Edwards Air Force Base in California concluding a successful assembly mission to the International Space Station. Atlantis landed on orbit 219 after 13 days, 20 hours and 12 minutes in space. The landing was diverted to California due to marginal weather at the Kennedy Space Center. Main gear touchdown was at 12:49:38 p.m. (PDT). Nose gear touchdown was at 12:49:49 p.m. and wheel stop was at 12:50:48 p.m. This was the 51st landing for the Space Shuttle Program at Edwards Air Force Base. The mission to the station was a success, installing and activating the S3/S4 truss and retracting the P6 arrays. Onboard were astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Steven Swanson, Patrick Forrester and John "Danny" Olivas, all STS-117 mission specialists. Also onboard was astronaut Sunita Williams, who was flight engineer on the Expedition 15 crew. She achieved a new milestone, a record-setting flight at 194 days, 18 hours and 58 minutes, the longest single spaceflight ever by a female astronaut or cosmonaut.

  16. Frequency and Correlates of Suicidal Ideation in Pediatric Obsessive-Compulsive Disorder

    PubMed Central

    Storch, Eric A.; Bussing, Regina; Jacob, Marni L.; Nadeau, Joshua M.; Crawford, Erika; Mutch, P. Jane; Mason, Dana; Lewin, Adam B.; Murphy, Tanya K.

    2014-01-01

    This study examined the frequency and sociodemographic and clinical correlates of suicidal ideation in a sample of children and adolescents with obsessive-compulsive disorder (OCD). Fifty-four youth with OCD and their parent(s) were administered the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime, Children’s Yale-Brown Obsessive Compulsive Scale, and Children’s Depression Rating Scale-Revised. Children completed the Suicidal Ideation Questionnaire - Junior, Child Obsessive Compulsive Impact Scale–Child, and Multidimensional Anxiety Scale for Children; parents completed the Child Obsessive Compulsive Impact Scale–Parent, Swanson, Nolan, and Pelham–IV Parent Scale, and Young Mania Rating Scale–Parent Version. Seven youth endorsed clinically significant levels of suicidal ideation on the Suicidal Ideation Questionnaire - Junior. Suicidal ideation was significantly related to clinician-rated depressive symptoms, age, child-rated impairment and anxiety symptoms, and symmetry, sexuality/religiosity and miscellaneous symptom dimensions. There was no significant association between suicidal ideation and obsessive-compulsive symptom severity, comorbidity patterns, or several parent-rated indices (e.g., impairment, impulsivity). These results provide initial information regarding the frequency and correlates of suicidal ideation in treatment-seeking youth with OCD. Clinical implications are discussed, as well as directions for future research. PMID:24682580

  17. Care Aides' Relational Practices and Caring Contributions.

    PubMed

    Andersen, Elizabeth A; Spiers, Jude

    2016-11-01

    HOW TO OBTAIN CONTACT HOURS BY READING THIS ARTICLE INSTRUCTIONS 1.2 contact hours will be awarded by Villanova University College of Nursing upon successful completion of this activity. A contact hour is a unit of measurement that denotes 60 minutes of an organized learning activity. This is a learner-based activity. Villanova University College of Nursing does not require submission of your answers to the quiz. A contact hour certificate will be awarded once you register, pay the registration fee, and complete the evaluation form online at http://goo.gl/gMfXaf. To obtain contact hours you must: 1. Read the article, "Care Aides' Relational Practices and Caring Contributions" found on pages 24-30, carefully noting any tables and other illustrative materials that are included to enhance your knowledge and understanding of the content. Be sure to keep track of the amount of time (number of minutes) you spend reading the article and completing the quiz. 2. Read and answer each question on the quiz. After completing all of the questions, compare your answers to those provided within this issue. If you have incorrect answers, return to the article for further study. 3. Go to the Villanova website listed above to register for contact hour credit. You will be asked to provide your name; contact information; and a VISA, MasterCard, or Discover card number for payment of the $20.00 fee. Once you complete the online evaluation, a certificate will be automatically generated. This activity is valid for continuing education credit until October 31, 2019. CONTACT HOURS This activity is co-provided by Villanova University College of Nursing and SLACK Incorporated. Villanova University College of Nursing is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation. ACTIVITY OBJECTIVES 1. Define the application of Swanson's Middle Range Theory of Caring in care aides' relational care practices for nursing home residents. 2. Describe how nursing home managers can empower care aides to provide care. DISCLOSURE STATEMENT Neither the planners nor the author have any conflicts of interest to disclose. The current study was a qualitative focused ethnography aimed at exploring the complexities of care; working environments; and knowledge, skills, and efforts of care aides who work in nursing homes. Over the past decade, dramatic shifts in staffing patterns in Canadian nursing homes have transformed care aides' assistive and caring roles. Care aides are now the central and most accessible service providers to nursing home residents. In the current article, the authors (a) conceptualize care aide work as caring rather than caring activities, (b) explore relational care as a foundational and significant component of care aide work, (c) interpret care aides' relational care practices through the lens of Swanson's Middle Range Theory of Caring, and (d) describe how nursing home managers can empower care aides to do this work. [Journal of Gerontological Nursing, 42(11), 24-30.]. Copyright 2016, SLACK Incorporated.

  18. Efficacy and Safety Extrapolation Analyses for Atomoxetine in Young Children with Attention-Deficit/Hyperactivity Disorder

    PubMed Central

    Kratochvil, Christopher; Ghuman, Jaswinder; Camporeale, Angelo; Lipsius, Sarah; D'Souza, Deborah; Tanaka, Yoko

    2015-01-01

    Abstract Objectives: This extrapolation analysis qualitatively compared the efficacy and safety profile of atomoxetine from Lilly clinical trial data in 6–7-year-old patients with attention-deficit/hyperactivity disorder (ADHD) with that of published literature in 4–5-year-old patients with ADHD (two open-label [4–5-year-old patients] and one placebo-controlled study [5-year-old patients]). Methods: The main efficacy analyses included placebo-controlled Lilly data and the placebo-controlled external study (5-year-old patients) data. The primary efficacy variables used in these studies were the ADHD Rating Scale-IV Parent Version, Investigator Administered (ADHD-RS-IV-Parent:Inv) total score, or the Swanson, Nolan and Pelham (SNAP-IV) scale score. Safety analyses included treatment-emergent adverse events (TEAEs) and vital signs. Descriptive statistics (means, percentages) are presented. Results: Acute atomoxetine treatment improved core ADHD symptoms in both 6–7-year-old patients (n=565) and 5-year-old patients (n=37) (treatment effect: −10.16 and −7.42). In an analysis of placebo-controlled groups, the mean duration of exposure to atomoxetine was ∼7 weeks for 6–7-year-old patients and 9 weeks for 5-year-old patients. Decreased appetite was the most common TEAE in atomoxetine-treated patients. The TEAEs observed at a higher rate in 5-year-old versus 6–7-year-old patients were irritability (36.8% vs. 3.6%) and other mood-related events (6.9% each vs. <3.0%). Blood pressure and pulse increased in both 4–5-year-old patients and 6–7-year-old patients, whereas a weight increase was seen only in the 6–7-year-old patients. Conclusions: Although limited by the small sample size of the external studies, these analyses suggest that in 5-year-old patients with ADHD, atomoxetine may improve ADHD symptoms, but possibly to a lesser extent than in older children, with some adverse events occurring at a higher rate in 5-year-old patients. PMID:25265343

  19. Remission in children and adolescents diagnosed with attention-deficit/hyperactivity disorder via an effective and tolerable titration scheme for osmotic release oral system methylphenidate.

    PubMed

    Chou, Wen-Jiun; Chen, Shin-Jaw; Chen, Ying-Sheue; Liang, Hsin-Yi; Lin, Chih-Chien; Tang, Ching-Shu; Huang, Yu-Shu; Yeh, Chin-Bin; Chou, Miao-Chun; Lin, Dai-Yueh; Hou, Po-Hsun; Wu, Yu-Yu; Liu, Hung-Jen; Huang, Ya-Fen; Hwang, Kai-Ling; Chan, Chin-Hong; Pan, Chia-Ho; Chang, Hsueh-Ling; Huang, Chi-Fen; Hsu, Ju-Wei

    2012-06-01

    The purpose of this study was to identify the optimal dose of osmotic release oral system methylphenidate (OROS-MPH) using a dosage forced-titration scheme to achieve symptomatic remission in children with attention- deficit/hyperactivity disorder (ADHD). We also evaluated the efficacy and safety of, and patient and parent satisfaction with, the change in therapy from immediate-release methylphenidate (IR-MPH) to OROS-MPH over 10 weeks. We recruited 521 children and adolescents aged 6-18 years with an American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders, 4th ed. (DSM-IV) diagnosis of ADHD, who had received IR-MPH treatments (<70 mg/day) for at least 1 month. The treatment, switched from IR-MPH to OROS-MPH according to a conversion scheme, started with a 6-week forced-titration phase of OROS-MPH to achieve symptomatic remission (defined as a score of 0 or 1 for each of the first 18 ADHD items in the Chinese version of the Swanson, Nolan, and Pelham, Version IV [SNAP-IV]), followed by a 4-week maintenance phase. The global ADHD severity and drug side effects of the participants were evaluated. Parents completed the ratings scales for the ADHD-related symptoms. Patient and parent satisfaction for the OROS-MPH treatment was also assessed. Among the 439 participants with ADHD who completed the trial, 290 participants (66.1%) achieved symptomatic remission. The mean dose of OROS-MPH among participants in remission was 36.7 mg (1.08 mg/kg) per day. Increased efficacy, superior satisfaction, and safety equivalent to that of IR-MPH were demonstrated in intra-individual comparisons from the baseline to the end of study. Determinants for remission included less severe ADHD symptoms (SNAP-IV score < 40), no family history of ADHD, and an appropriate dosage of medication according to the patient's weight. The findings suggest remission as a treatment goal for ADHD therapy by providing an optimal dosage of medication for children and adolescents with ADHD through using an effective and tolerable forced-titration scheme.

  20. Juxtaposition of contrasting structural regimes across a portion of the Norumbega fault system in the northern Casco Bay region of Maine

    NASA Astrophysics Data System (ADS)

    West, D. P., Jr.; Hussey, A. M., II

    2015-12-01

    It has long been recognized that Paleozoic stratified rocks in some regions of central New England are dominated by relatively flat structural features (e.g., recumbent folds, shallow dipping foliation) while other areas are dominated by near vertical upright structures. The northern Casco Bay region of coastal Maine (Brunswick 7.5' quadrangle and adjacent areas) provides an excellent venue for studying the relationships between these two structural regimes as they are in close proximity due to juxtaposition by high angle faulting associated with the Norumbega fault system. Stratified rocks exposed west of the Flying Point fault in northern Casco Bay are dominated by moderately east dipping foliation (ave. = 025o, 37o), moderate northeast plunging mineral lineations, and recumbent to gently inclined minor folds. In stark contrast, immediately east of the Flying Point fault, stratified rocks are dominated by steep east dipping foliation (ave. = 014o, 73o), subhorizontal mineral lineations, and upright to steeply inclined minor folds. The structural differences correspond directly to differences in the thermal histories preserved in these rocks as revealed by earlier thermochronological studies. Rocks in the zone of upright structures east of the Flying Point fault were last subjected to high grade metamorphic conditions and granitic plutonism in the Late Devonian and were relatively cold (<300oC) by Late Carboniferous time. In contrast, flat lying rocks west of the Flying Point fault were over 500oC in the Early Permian and Permian pegmatites are common. Geochronological studies north of the study area have revealed that the two distinctly different structural styles are not the product of strain partitioning during the same deformational episode, but rather they represent two temporally and kinematically distinct deformational events. Swanson (1999), originally suggested flat structures west of the Flying Point fault are consistent with an episode of northwest directed thrusting and our findings are consistent with this interpretation. However, this flat phase of deformation significantly post-dates the older upright structures preserved to the east and thus models for the structural evolution of the region must integrate both the kinematic and temporal differences in this deformation.

  1. Geologic Map of the Woodland Quadrangle, Clark and Cowlitz Counties, Washington

    USGS Publications Warehouse

    Evarts, Russell C.

    2004-01-01

    The Woodland 7.5' quadrangle is situated in the Puget-Willamette Lowland approximately 50 km north of Portland, Oregon (fig. 1). The lowland, which extends from Puget Sound into west-central Oregon, is a complex structural and topographic trough that lies between the Coast Range and the Cascade Range. Since late Eocene time, the Cascade Range has been the locus of an active volcanic arc associated with underthrusting of oceanic lithosphere beneath the North American continent along the Cascadia Subduction Zone. The Coast Range occupies the forearc position within the Cascadia arc-trench system and consists of a complex assemblage of Eocene to Miocene volcanic and marine sedimentary rocks. The Woodland quadrangle lies at the northern edge of the Portland Basin, a roughly 2000-km2 topographic and structural depression that is the northernmost of several sediment-filled structural basins, which collectively constitute the Willamette Valley segment of the Puget-Willamette Lowland (Beeson and others, 1989; Swanson and others, 1993; Yeats and others, 1996). The Portland Basin is approximately 70 km long and 30 km wide; its long dimension is oriented northwest. Its northern boundary coincides, in part, with the lower Lewis River, which flows westward through the center of the quadrangle. The Lewis drains a large area in the southern Washington Cascade Range, including the southern flank of Mount St. Helens approximately 25 km upstream from the quadrangle, and joins the Columbia River about 6 km south of Woodland (fig. 1). Northwest of Woodland, the Columbia River exits the broad floodplain of the Portland Basin and flows northward through a relatively narrow bedrock valley at an elevation near sea level. The flanks of the Portland Basin consist of Eocene through Miocene volcanic and sedimentary rocks that rise to elevations exceeding 2000 ft (610 m). Seismic-reflection profiles (L.M. Liberty, written commun., 2003) and lithologic logs of water wells (Swanson and others, 1993; Mabey and Madin, 1995) indicate that as much as 550 m of late Miocene and younger sediments have accumulated in the deepest part of the basin near Vancouver. Most of this basin-fill material was carried in from the east by the Columbia River but sediment deposited by streams draining the adjacent highlands are locally important. The Portland Basin has been interpreted as a pull-apart basin located in the releasing stepover between two en echelon, northwest-striking, right-lateral fault zones (Beeson and others, 1985, 1989; Beeson and Tolan, 1990; Yelin and Patton, 1991; Blakely and others, 1995). These fault zones are thought to reflect regional transpression and dextral shear within the forearc in response to oblique subduction of the Pacific Plate along the Cascadia Subduction Zone (Pezzopane and Weldon, 1993; Wells and others, 1998). The southwestern margin of the Portland Basin is a well-defined topographic break along the base of the Tualatin Mountains, an asymmetric anticlinal ridge that is bounded on its northeast flank by the Portland Hills Fault Zone (Balsillie and Benson, 1971; Beeson and others, 1989; Blakely and others, 1995), which is probably an active structure (Wong and others, 2001; Liberty and others, 2003). The nature of the corresponding northeastern margin of the basin is less clear, but a poorly defined and partially buried dextral extensional fault zone has been hypothesized from topography, microseismicity, potential field-anomalies, and reconnaissance geologic mapping (Beeson and others, 1989; Beeson and Tolan, 1990; Yelin and Patton, 1991; Blakely and others, 1995). Another dextral structure may control the north-northwest-trending reach of the Columbia River between Portland and Longview (Blakely and others, 1995; Evarts, 2002; Evarts and others, 2002). This map is a contribution to a U.S. Geological Survey program designed to improve the geologic database for the Portland Basin part of the Pacific Northwest urban corridor,

  2. Geologic Map of the Saint Helens Quadrangle, Columbia County, Oregon, and Clark and Cowlitz Counties, Washington

    USGS Publications Warehouse

    Evarts, Russell C.

    2004-01-01

    The Saint Helens 7.5' quadrangle is situated in the Puget-Willamette Lowland approximately 35 km north Portland, Oregon. The lowland, which extends from Puget Sound into west-central Oregon, is a complex structural and topographic trough that lies between the Coast Range and the Cascade Range. Since late Eocene time, Cascade Range has been the locus of a discontinuously active volcanic arc associated with underthrusting of oceanic lithosphere beneath the North American continent along the Cascadia Subduction Zone. The Coast Range occupies the forearc position within the Cascadia arc-trench system and consists of a complex assemblage of Eocene to Miocene volcanic and marine sedimentary rocks. The Saint Helens quadrangle lies in the northern part of the Portland Basin, a roughly 2000-km2 topographic and structural depression. It is the northernmost of several sediment-filled structural basins that collectively constitute the Willamette Valley segment of the Puget-Willamette Lowland (Beeson and others, 1989; Swanson and others, 1993; Yeats and others, 1996). The rhomboidal basin is approximately 70 km long and 30 km wide, with its long dimension oriented northwest. The Columbia River flows west and north through the Portland Basin at an elevation near sea level and exits through a confined bedrock valley less than 2.5 km wide about 16 km north of Saint Helens. The flanks of the basin consist of Eocene through Miocene volcanic and sedimentary rocks that rise to elevations exceeding 2000 ft (610 m). Seismic-reflection profiles (L.M. Liberty, written commun., 2003) and lithologic logs of water wells (Swanson and others, 1993; Mabey and Madin, 1995) indicate that as much as 550 m of late Miocene and younger sediments have accumulated in the deepest part of the basin near Vancouver. Most of this basin-fill material was carried in from the east by the Columbia River but contributions from streams draining the adjacent highlands are locally important. The Portland Basin has been interpreted as a pull-apart basin located in the releasing stepover between two echelon, northwest-striking, right-lateral fault zones (Beeson and others, 1985, 1989; Beeson and Tolan, 1990; Yelin and Patton, 1991; Blakely and others, 1995). These fault zones are thought to reflect regional transpression and dextral shear within the forearc in response to oblique subduction along the Cascadia Subduction Zone Pezzopane and Weldon, 1993; Wells and others, 1998). The southwestern margin of the Portland Basin is a well-defined topographic break along the base of the Tualatin Mountains, an asymmetric anticlinal ridge that is bounded its northeast flank by the Portland Hills Fault Zone (Balsillie and Benson, 1971; Beeson and others, 1989; Blakely and others, 1995), which is probably an active structure (Wong and others, 2001; Liberty and others, 2003). The nature of the corresponding northeastern margin of the basin is less clear, but a poorly defined and partially buried dextral extensional fault zone has been hypothesized from topography, microseismicity, potential fieldanomalies, and reconnaissance geologic mapping (Beeson and others, 1989; Beeson and Tolan, 1990; Yelin and Patton, 1991; Blakely and others, 1995). Another dextral structure, the Kalama Structural Zone of Evarts (2002), may underlie the north-northwest-trending reach of the Columbia River north of Woodland (Blakely and others, 1995). This map is a contribution to a U.S. Geological Survey (USGS) program designed to improve the geologic database for the Portland Basin region of the Pacific Northwest urban corridor, the populated forearc region of western Washington and Oregon. Better and more detailed information on the bedrock and surficial geology of the basin and its surrounding area is needed to refine assessments of seismic risk (Yelin and Patton, 1991; Bott and Wong, 1993), ground-failure hazards (Madin and Wang, 1999; Wegmann and Walsh, 2001) and resource availability in this rapid

  3. CARES - CERAMICS ANALYSIS AND RELIABILITY EVALUATION OF STRUCTURES

    NASA Technical Reports Server (NTRS)

    Nemeth, N. N.

    1994-01-01

    The beneficial properties of structural ceramics include their high-temperature strength, light weight, hardness, and corrosion and oxidation resistance. For advanced heat engines, ceramics have demonstrated functional abilities at temperatures well beyond the operational limits of metals. This is offset by the fact that ceramic materials tend to be brittle. When a load is applied, their lack of significant plastic deformation causes the material to crack at microscopic flaws, destroying the component. CARES calculates the fast-fracture reliability or failure probability of macroscopically isotropic ceramic components. These components may be subjected to complex thermomechanical loadings. The program uses results from a commercial structural analysis program (MSC/NASTRAN or ANSYS) to evaluate component reliability due to inherent surface and/or volume type flaws. A multiple material capability allows the finite element model reliability to be a function of many different ceramic material statistical characterizations. The reliability analysis uses element stress, temperature, area, and volume output, which are obtained from two dimensional shell and three dimensional solid isoparametric or axisymmetric finite elements. CARES utilizes the Batdorf model and the two-parameter Weibull cumulative distribution function to describe the effects of multi-axial stress states on material strength. The shear-sensitive Batdorf model requires a user-selected flaw geometry and a mixed-mode fracture criterion. Flaws intersecting the surface and imperfections embedded in the volume can be modeled. The total strain energy release rate theory is used as a mixed mode fracture criterion for co-planar crack extension. Out-of-plane crack extension criteria are approximated by a simple equation with a semi-empirical constant that can model the maximum tangential stress theory, the minimum strain energy density criterion, the maximum strain energy release rate theory, or experimental results. For comparison, Griffith's maximum tensile stress theory, the principle of independent action, and the Weibull normal stress averaging models are also included. Weibull material strength parameters, the Batdorf crack density coefficient, and other related statistical quantities are estimated from four-point bend bar or uniform uniaxial tensile specimen fracture strength data. Parameter estimation can be performed for single or multiple failure modes by using the least-squares analysis or the maximum likelihood method. A more limited program, CARES/PC (COSMIC number LEW-15248) runs on a personal computer and estimates ceramic material properties from three-point bend bar data. CARES/PC does not perform fast fracture reliability estimation. CARES is written in FORTRAN 77 and has been implemented on DEC VAX series computers under VMS and on IBM 370 series computers under VM/CMS. On a VAX, CARES requires 10Mb of main memory. Five MSC/NASTRAN example problems and two ANSYS example problems are provided. There are two versions of CARES supplied on the distribution tape, CARES1 and CARES2. CARES2 contains sub-elements and CARES1 does not. CARES is available on a 9-track 1600 BPI VAX FILES-11 format magnetic tape (standard media) or in VAX BACKUP format on a TK50 tape cartridge. The program requires a FORTRAN 77 compiler and about 12Mb memory. CARES was developed in 1990. DEC, VAX and VMS are trademarks of Digital Equipment Corporation. IBM 370 is a trademark of International Business Machines. MSC/NASTRAN is a trademark of MacNeal-Schwendler Corporation. ANSYS is a trademark of Swanson Analysis Systems, Inc.

  4. KSC-2009-2048

    NASA Image and Video Library

    2009-03-15

    CAPE CANAVERAL, Fla. – The STS-119 crew members head for the Astrovan to take them to Launch Pad 39A at NASA's Kennedy Space Center in Florida for launch of space shuttle Discovery to the International Space Station. From left are Mission Specialists John Phillips, Koichi Wakata, Steve Swanson and Richard Arnold, Pilot Tony Antonelli, Mission Specialist Joseph Acaba (behind Antonelli) and Commander Lee Archambault. Wakata represents the Japan Aerospace Exploration Agency and will remain on the International Space Station, replacing Expedition 18 Flight Engineer Sandra Magnus, who returns to Earth with the STS-119 crew. Liftoff of Discovery is scheduled for 7:43 p.m. EDT on March 15. An earlier launch attempt March 11 was scrubbed at 2:36 p.m. due to a gaseous hydrogen leak from the external tank at the Ground Umbilical Carrier Plate during tanking. A seven-inch quick disconnect and two seals were replaced. The STS-119 mission is the 28th to the space station and the 125th space shuttle flight. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science. Photo credit: NASA/Kim Shiflett

  5. Evaluation of switchable organic devices for nonvolatile memory applications

    NASA Astrophysics Data System (ADS)

    Campbell Scott, J.

    2007-03-01

    Many organic electronic devices exhibit switching behavior and have therefore been proposed as the basis for a nonvolatile memory technology. In particular, bistable resistive elements, in which a high or low current state is selected by application of a specific voltage, may be used as the elements of a crosspoint memory array. This architecture places very stringent requirements on the electrical response of the individual devices, in terms of on-state current density, switching and retention times, cycling endurance, rectification and size-scaling. In this talk, I will describe the progress that we and others have made towards satisfying these requirements. In many cases, the mechanisms responsible for conduction and switching are not fully understood. In some devices, it has been shown that current flows in a few highly localized regions. These so-called ``filaments'' are not necessarily metallic bridges between the electrodes, but may be associated with chains of nanoparticles introduced into the organic matrix either deliberately or accidentally. Coulomb blockade effects can then explain the switching behavior observed in some devices. This work was done in collaboration with L. D. Bozano, M. Beinhoff, K. R. Carter, V. R. Deline, B. W. Kean, G. M. McClelland, D. C. Miller, P. M. Rice, J. R. Salem, and S. A. Swanson.

  6. Importance of geology to fisheries management: Examples from the northeastern Gulf of Mexico

    USGS Publications Warehouse

    Scanlon, Kathryn M.; Koenig, C.C.; Coleman, F.C.; Miller, M.

    2003-01-01

    Seafloor mapping of shelf-edge habitats in the northeastern Gulf of Mexico demonstrates how sidescan-sonar imagery, seismic-reflection profiling, video data, geologic mapping, sediment sampling, and understanding the regional geologic history can enhance, support, and guide traditional fisheries research and management. New data from the Madison Swanson and Steamboat Lumps Marine Reserves reveal complex benthic habitats consisting of high-relief calcareous pinnacles, low-relief karstic hardbottom, rocky outcrops several kilometers in length, and variable thickness of fine-grained and apparently mobile coarse-grained sediments. Our data also show that certain fish alter the landscape by clearing sediment from hardbottom areas (e.g., red grouper Epinephelus morio) and by burrowing extensively in fine-grained sediment (e.g., tilefish Lopholatilus chamaeleonticeps). The seafloor imagery and geologic maps show that (a) sea level fluctuations played a dominant role in the development of the present-day regional geology, and (b) habitats (and benthic communities) are tied closely to geologic character. Understanding the geologic setting allowed for efficient and representative sampling of the biology. The geologic data can be used to set meaningful boundaries for fishery reserves and to help predict habitats in areas that are not well mapped. This interdisciplinary work added value to traditional research disciplines by providing management with integrated tools to make better decisions. 

  7. Effect of Atomoxetine on the Cognitive Functions in Treatment of Attention Deficit Hyperactivity Disorder in Children with Congenital Hypothyroidism: A Pilot Study.

    PubMed

    Yang, Rongwang; Gao, Weijia; Li, Rong; Zhao, Zhengyan

    2015-04-19

    With early initiation of thyroxine supplementation, children with congenital hypothyroidism (CH) retain some subtle deficits, such as attention and inhibitory control problems. This study assessed the effects of atomoxetine on cognitive functions in treatment of attention deficit hyperactivity disorder (ADHD) symptoms in children with CH. In a 6-month, open-labeled pilot study, 12 children were recruited and received atomoxetine. The measures of efficacy were scores on the Swanson, Nolan and Pelham Teacher and Parent Rating Scale, version IV (SNAP-IV) and Clinical Global Impression-Severity scale (CGI-S). The cognitive functions were evaluated with the Wechsler Intelligence Scale for Chinese Children, Digit Span, Wisconsin Card Sorting Test, and Stroop test. A statistically significant difference was found between the mean CGI-S and SNAP-IV scores before and after treatment (p < 0.01). All the indicators of cognitive functions at the endpoint were improved compared with those at baseline. No serious adverse events were reported. Atomoxetine appears to be useful in improving ADHD symptoms, as well as cognitive functions, in children with CH. Larger, randomized, double-blinded, clinical trials are required to replicate these results. © The Author 2015. Published by Oxford University Press on behalf of CINP.

  8. The JIM interview. Art Levinson, PhD.

    PubMed

    Levinson, A

    1997-06-01

    In the early 1980s several prominent scientists left the hallowed halls of respected universities seeking to exploit the revolution occurring in biology in an environment devoid of the bureaucratic and political confines of academia. The emergence of the biotechnology industry has been marked by both spectacular failures and success stories. Genentech was founded in 1976 by biochemist Herbert Boyer and venture capitalist Robert Swanson and went public in 1980. In 1995 Genentech merged with Roche Holdings Ltd., of Basel Switzerland. Distinguished from other biotech companies by the varied array of products it has brought to market, Genentech has also developed a unique corporate culture embodying many traditional academic values. Just as Genentech went public in 1980, Arthur D. Levinson, PhD, finished a post-doctoral appointment in Michael Bishop's lab at the University of California, San Francisco. Despite the disapproval of colleagues, he joined the fledgling company as a senior scientist. Working his way though the ranks, Levinson became Vice President of Research Technology in 1989 and was named President and CEO in 1995. Interviewed at the sprawling corporate headquarters in South San Francisco, Levinson reflected on the process of high risk science, the benefits of the private sector, and the changing relationship between biotech companies and the academic world.

  9. STS-117 landing at Dryden

    NASA Image and Video Library

    2007-06-22

    STS117-S-050 (22 June 2007) --- With drag chute deployed, Space Shuttle Atlantis slows to a stop after landing on runway 22 at NASA's Dryden Flight Research Center at Edwards Air Force Base in California concluding a successful assembly mission to the International Space Station. Atlantis landed on orbit 219 after 13 days, 20 hours and 12 minutes in space. The landing was diverted to California due to marginal weather at the Kennedy Space Center. Main gear touchdown was at 12:49:38 p.m. (PDT). Nose gear touchdown was at 12:49:49 p.m. and wheel stop was at 12:50:48 p.m. This was the 51st landing for the Space Shuttle Program at Edwards Air Force Base. The mission to the station was a success, installing and activating the S3/S4 truss and retracting the P6 arrays. Onboard were astronauts Rick Sturckow, commander; Lee Archambault, pilot; Jim Reilly, Steven Swanson, Patrick Forrester and John "Danny" Olivas, all STS-117 mission specialists. Also onboard was astronaut Sunita Williams, who was flight engineer on the Expedition 15 crew. She achieved a new milestone, a record-setting flight at 194 days, 18 hours and 58 minutes, the longest single spaceflight ever by a female astronaut or cosmonaut.

  10. Measuring methylphenidate response in attention-deficit/hyperactvity disorder: how are laboratory classroom-based measures related to parent ratings?

    PubMed

    Sonuga-Barke, Edmund J S; Coghill, David; DeBacker, Marc; Swanson, James

    2009-12-01

    Methylphenidate (MPH) is an efficacious and normally well-tolerated treatment for attention-deficit/hyperactivity disorder (ADHD). Although treatment effects are usually assessed using parent-rating scales, these can be supplemented by more objective methods. Here we examine the associations between ratings and one such method, assessments made across the day in the laboratory classroom. Comparison of Methylphenidates in the Analog Classroom Setting (COMACS) was made in a large (n = 184) placebo-controlled trial comparing Equasym XL/Metadate CD, Concerta, and placebo (PLA) using a Laboratory School protocol. Therapeutic effects were measured using direct observation, scores on a simple math productivity task and parent ratings. Treatment effects were observed on all measures. Laboratory measures were correlated with each other, most strongly between Swanson, Kotkin, Agler, M-Flynn and Pelham Scale (SKAMP) inattention and Permanent Product Measure of Performance (PERMP). Parental ratings were correlated with classroom measures during the main morning period (1.5-4.5 hours after dosing) and to a lesser extent in the afternoon (6.0-7.5 hours after dosing), but not, by and large, immediately after dosing or in the evening. The morning correlations seemed stronger for female than for male participants. The results suggest that parental ratings and direct observations tap different aspects of MPH response and that both may be required for comprehensive assessment.

  11. Enriching plausible new hypothesis generation in PubMed.

    PubMed

    Baek, Seung Han; Lee, Dahee; Kim, Minjoo; Lee, Jong Ho; Song, Min

    2017-01-01

    Most of earlier studies in the field of literature-based discovery have adopted Swanson's ABC model that links pieces of knowledge entailed in disjoint literatures. However, the issue concerning their practicability remains to be solved since most of them did not deal with the context surrounding the discovered associations and usually not accompanied with clinical confirmation. In this study, we aim to propose a method that expands and elaborates the existing hypothesis by advanced text mining techniques for capturing contexts. We extend ABC model to allow for multiple B terms with various biological types. We were able to concretize a specific, metabolite-related hypothesis with abundant contextual information by using the proposed method. Starting from explaining the relationship between lactosylceramide and arterial stiffness, the hypothesis was extended to suggest a potential pathway consisting of lactosylceramide, nitric oxide, malondialdehyde, and arterial stiffness. The experiment by domain experts showed that it is clinically valid. The proposed method is designed to provide plausible candidates of the concretized hypothesis, which are based on extracted heterogeneous entities and detailed relation information, along with a reliable ranking criterion. Statistical tests collaboratively conducted with biomedical experts provide the validity and practical usefulness of the method unlike previous studies. Applying the proposed method to other cases, it would be helpful for biologists to support the existing hypothesis and easily expect the logical process within it.

  12. PREFACE: Second Meeting of the APS Topical Group on Hadronic Physics

    NASA Astrophysics Data System (ADS)

    Ernst, David; de Jager, Kees; Roberts, Craig; Sheldon, Paul; Swanson, Eric

    2007-06-01

    The Second Meeting of the APS Topical Group on Hadronic Physics was held on 22-24 October 2006 at the Opryland Resort in Nashville, Tennessee. Keeping with tradition, the meeting was held in conjunction with the Fall meeting of the APS Division of Nuclear Physics. Approximately 90 physicists participated in the meeting, presenting 25 talks in seven plenary sessions and 48 talks in 11 parallel sessions. These sessions covered a wide range of topics related to strongly interacting matter. Among these were charm spectroscopy, gluonic exotics, nucleon resonance physics, RHIC physics, electroweak and spin physics, lattice QCD initiatives, and new facilities. Brad Tippens and Brad Keister provided perspective from the funding agencies. The organisers are extremely grateful to the following institutions for financial and logistical support: the American Physical Society, Jefferson Lab, Brookhaven National Laboratory, and Vanderbilt University. We thank the following persons for assisting in organising the parallel sessions: Ted Barnes, Jian-Ping Chen, Ed Kinney, Krishna Kumar, Harry Lee, Mike Leitch, Kam Seth, and Dennis Weygand. We also thank Gerald Ragghianti for designing the conference poster, Will Johns for managing the audio-visual equipment and for placing the talks on the web, Sandy Childress for administrative expertise, and Vanderbilt graduate students Eduardo Luiggi and Jesus Escamillad for their assistance. David Ernst, Kees de Jager, Craig Roberts (Chair), Paul Sheldon and Eric Swanson Editors

  13. ADHD and autistic traits, family function, parenting style, and social adjustment for Internet addiction among children and adolescents in Taiwan: a longitudinal study.

    PubMed

    Chen, Yi-Lung; Chen, Sue-Huei; Gau, Susan Shur-Fen

    2015-04-01

    This longitudinal study investigated the prevalence, predictors, and related factors for Internet addiction among elementary and junior high school students in Taiwan. A convenient sample of grades 3, 5, and 8 students (n = 1153) was recruited from six elementary and one junior high schools. They were assessed during the beginning and the end of the spring semester of 2013. Internet addiction was examined by the Chen Internet Addiction Scale (CIAS). Other factors were screened using the Chinese version of the Autism Spectrum Quotient (AQ) for autistic trait, the Parental Bonding Instrument (PBI) for parenting, the Family APGAR for family support, the Social Adjustment Inventory for Children and Adolescents for social function, and the Swanson, Nolan, and Pelham, version IV scale (SNAP-IV) for ADHD symptoms. The prevalence of Internet addiction decreased from 11.4% to 10.6%. Male, low family support, poor social adjustment, and high ADHD-related symptoms were related to Internet addiction. However, there was an inverse relationship between autistic traits and Internet addiction. Further, its predictivity could be accounted by poor academic performance, male, and protective parenting style. Internet addiction is not uncommon among youths in Taiwan. The predictors identified in this study could be the specific measures for the development of a prevention program for Internet addiction in the youth population. Copyright © 2015 Elsevier Ltd. All rights reserved.

  14. A vector space model approach to identify genetically related diseases.

    PubMed

    Sarkar, Indra Neil

    2012-01-01

    The relationship between diseases and their causative genes can be complex, especially in the case of polygenic diseases. Further exacerbating the challenges in their study is that many genes may be causally related to multiple diseases. This study explored the relationship between diseases through the adaptation of an approach pioneered in the context of information retrieval: vector space models. A vector space model approach was developed that bridges gene disease knowledge inferred across three knowledge bases: Online Mendelian Inheritance in Man, GenBank, and Medline. The approach was then used to identify potentially related diseases for two target diseases: Alzheimer disease and Prader-Willi Syndrome. In the case of both Alzheimer Disease and Prader-Willi Syndrome, a set of plausible diseases were identified that may warrant further exploration. This study furthers seminal work by Swanson, et al. that demonstrated the potential for mining literature for putative correlations. Using a vector space modeling approach, information from both biomedical literature and genomic resources (like GenBank) can be combined towards identification of putative correlations of interest. To this end, the relevance of the predicted diseases of interest in this study using the vector space modeling approach were validated based on supporting literature. The results of this study suggest that a vector space model approach may be a useful means to identify potential relationships between complex diseases, and thereby enable the coordination of gene-based findings across multiple complex diseases.

  15. Classification for congenital anomalies of the hand: the IFSSH classification and the JSSH modification.

    PubMed

    De Smet, L

    2002-01-01

    The purpose of a classification for clinical problems which, except for a few specialized centers, occur only sporadically is to provide a system where these cases can be stored. This should allow all involved investigators to speak the same language; so-doing syndromes can be delinated, frequencies of occurence established and results of--different--treatments compared. A classification system should be simple to use, reliable and uniformly accepted. It should allow space for adaptations and/or extensions. The IFSSH proposed a 7 categories classification based on the proposed classification of Swanson et al. in 1976. This classification, was based on, which was thought in the seventies, etiopathogenic pathways. These 7 groups are: I. Failure of formation; transverse (A), or longitudinal (B) II. Failure of differentiation III. Polydactyly IV. Overgrowth V. Undergrowth VI. Amniotic band syndrome VII. Generalized skeletal syndromes. The extended classification proposed by IFSSH was used to classify 1013 hand differences in 925 hands of 650 patients. We found associated anomalies in 26.7%. The classification was straightforward in 86%, difficult in 6.6% and not possible in 7.8%. Group II was the most numerous group including 513 anomalies. We propose to include in this group the Madelung deformity, the Kirner deformity and congenital trigger fingers and trigger thumbs. In group I the radial and ulnar deficiencies, limited to the hand without forearm deficlencies should be Included. Triphalangeal thumbs are a problem, we suggest it to be listed in group III and consider it as a duplication in length. It is not always possible to evaluate the (transverse) absence of the fingers or hand. Longitudinal deficiencies (group IIB), symbrachydactyly (group V), and amniotic bands (group IV) occasionally develop a phenotype similar to the genuine transverse deficiency (group IA). Recently, the Japanese Society for Surgery of the Hand (JSSH) (16) proposed an extension/modification of the IFSSH classification. Based on newer knowledge on teratology, symbrachydactyly in all stages were transfered to group I. Two new groups were introduced. A group "failure of finger ray induction" including typical cleft hand (IC), central polydactyly (III) and (bony) syndactyly (II)--was included. Also a group of "unclassifiable" cases was added. This Japanese proposed classification is a real improvement and most clinicians and surgeons tend to use it in the future.

  16. Attention Deficit/Hyperactivity Disorder and Urinary Nonylphenol Levels: A Case-Control Study in Taiwanese Children

    PubMed Central

    Yu, Ching-Jung; Du, Jung-Chieh; Chiou, Hsien-Chih; Yang, Shang-Han; Liao, Kai-Wei; Yang, Winnie; Chung, Ming-Yi; Chien, Ling-Chu; Hwang, Betau; Chen, Mei-Lien

    2016-01-01

    Objective Nonylphenol (NP) belongs to the family of endocrine disruptors, and it is widely used in industrial applications and is ubiquitous in daily foods. Animal studies have suggested that NP exposure might promote motor hyperactivity, likely by causing deficits in dopaminergic neurons. However, research assessing NP exposure and epidemiology studies on human populations are limited. The aim of this study was to explore the association between child NP exposure and ADHD while considering particular covariants, such as lead levels and dopamine-related gene variations. Methods A case-control study was conducted on patients with clinically diagnosed ADHD; the Swanson, Nolan and Pelham, Fourth Revision (SNAP-IV) questionnaire was used to identify normal controls aged 4–15 years. Participants were examined for urinary NP concentrations, blood lead levels, and select single-nucleotide polymorphisms of two dopamine-related genes (D4 dopamine receptor, DRD4, and dopamine transporter, DAT1). Socio-demographic variables, maternal lifestyle factors during pregnancy and family medical history were obtained using a questionnaire. Results A total of 97 children with doctor-diagnosed ADHD and 110 normal controls were enrolled. The blood lead levels in both groups were similar (1.57±0.73 vs. 1.73±0.77 μg/dL, p = 0.15). No significant difference in urinary NP concentration was found between the children with ADHD and the control subjects (4.52±3.22 μg/g cr. vs. 4.64±2.95 μg/g cr., p = 0.43). ADHD was significantly more prevalent among males in this study (male to female ratio: 5:1 for the ADHD group and 1.3:1 for the control group, p<0.01). The analysis was repeated after excluding the females, but this had no effect on the association between NP and ADHD. The regression model, including or excluding females, indicated no increased odds of having ADHD in the context of NP exposure after adjusting for covariants. Conclusion This study indicated that NP exposure might not promote ADHD in children, even though children in Taiwan had relatively high levels of NP compared to those reported previously and those in developed nations. PMID:26890918

  17. Streamflow gain/loss in the Republican River basin, Nebraska, March 1989

    USGS Publications Warehouse

    Johnson, Michaela R.; Stanton, Jennifer S.; Cornwall, James F.; Landon, Matthew K.

    2002-01-01

    This arc and point data set contains streamflow measurement sites and reaches indicating streamflow gain or loss under base-flow conditions along the Republican River and tributaries in Nebraska during March 21 to 22, 1989 (Boohar and others, 1990). These measurements were made to obtain data on ground-water/surface-water interaction. Flow was visually observed to be zero, was measured, or was estimated at 136 sites. The measurements were made on the main stem of the Republican River and all flowing tributaries that enter the Republican River above Swanson Reservoir and parts of the Frenchman, Red Willow, and Medicine Creek drainages in the Nebraska part of the Republican River Basin. Tributaries were followed upstream until the first road crossing where zero flow was encountered. For selected streams, points of zero flow upstream of the first zero flow site were also checked. Streamflow gain or loss for each stream reach was calculated by subtracting the streamflow values measured at the upstream end of the reach and values for contributing tributaries from the downstream value. The data obtained reflected base-flow conditions suitable for estimating streamflow gains and losses for stream reaches between sites. This digital data set was created by manually plotting locations of streamflow measurements. These points were used to designate stream-reach segments to calculate gain/loss per river mile. Reach segments were created by manually splitting the lines from a 1:250,000 hydrography data set (Soenksen and others, 1999) at every location where the streams were measured. Each stream-reach segment between streamflow-measurement sites was assigned a unique reach number. All other lines in the hydrography data set without reach numbers were omitted. This data set was created to archive the calculated streamflow gains and losses of selected streams in part of the Republican River Basin, Nebraska in March 1989, and make the data available for use with geographic information systems (GIS). If measurement sites are used separately from reaches, the maximum scale of 1:100,000 should not be exceeded. When used in conjunction with the reach segments, the maximum scale should not exceed 1:250,000.

  18. Is Eruption Style Linked to Magma Residence Time at Kilauea Volcano? Results from Chemical Zoning in Olivine

    NASA Astrophysics Data System (ADS)

    Lynn, K. J.; Costa Rodriguez, F.; Shea, T.; Garcia, M. O.

    2015-12-01

    Kilauea is generally characterized by its modern effusive activity, but the past 2500 years were dominated by cycles of explosive and effusive eruptions lasting 100's of years (Swanson et al. 2012). These different eruption styles may reflect variable volatile contents in the source that control magma ascent rate and storage durations (e.g., Sides et al. 2014). A detailed petrological study of the dominantly explosive Keanakako'i tephras (1500-1820 CE) was undertaken to better understand the storage and transport conditions preceding high-energy eruptions. Here, we focus on preliminary results for olivine from the 1500 CE Basal Reticulite (>600 m fountain; May et al. 2015). Olivine major (Fe, Mg), minor (Mn, Ca, Ni) and trace (Li, Na, Al, P, Sc, Ti, V, Cr, Co, Zn) element traverses and 2D maps were collected for 10 crystals and reveal two major populations. The dominant population has homogeneous Fo89 and Fo87 cores with thin (3-12 μm) rims of intermediate composition (Fo87.5-88.5). Normal, reverse, and complex trace element zoning (Al, P, Ti, Cr) is prominent in these otherwise homogenous (Fo, Ni, Ca, Mn) crystals. 2D maps reveal early skeletal growth and the progressive decrease of Cr from core to rim suggests olivine and Cr-spinel crystallization, which should produce significant Fo zoning. Absence of Fo zoning could imply significant storage time in a reservoir allowing homogenization. The majority of rim compositions are out of equilibrium with adhering glass, and Fe-Mg modeling indicates that their residence within the carrier melt was of a few days. A second population consists of strongly zoned (normal and reverse) crystals with a wide range of core Fo (78 to 89) and Fo82-84 rims. Timescales from Fe-Mg zoning are up to 1 year, and may record storage histories before interaction with the carrier melt. The diversity in olivine zoning suggests at least two stages of magma mixing, and a more complex evolution for the magmas that fed the reticulite eruptions than a simple closed-system and fast transport of a volatile-rich magma from the source to the surface.

  19. An Open-Label, Randomized Trial of Methylphenidate and Atomoxetine Treatment in Children with Attention-Deficit/Hyperactivity Disorder.

    PubMed

    Shang, Chi-Yung; Pan, Yi-Lei; Lin, Hsiang-Yuan; Huang, Lin-Wan; Gau, Susan Shur-Fen

    2015-09-01

    The efficacy of both methylphenidate and atomoxetine has been established in placebo-controlled trials. The present study aimed to directly compare the efficacy of methylphenidate and atomoxetine in improving symptoms among children with attention-deficit/hyperactivity disorder (ADHD). The study sample included 160 drug-naïve children and adolescents 7-16 years of age, with DSM-IV-defined ADHD, randomly assigned to osmotic-release oral system methylphenidate (OROS-methylphenidate) (n=80) and atomoxetine (n=80) in a 24 week, open-label, head-to-head clinical trial. The primary efficacy measure was the score of the ADHD Rating Scale-IV Parents Version: Investigator Administered and Scored (ADHD-RS-IV). The secondary efficacy measures included the Clinical Global Impressions-ADHD-Severity (CGI-ADHD-S) and Chinese Swanson, Nolan, and Pelham IV scale (SNAP-IV), based on the ratings of investigators, parents, teachers, and subjects. At week 24, mean changes in ADHD-RS-IV Inattention scores were 13.58 points (Cohen's d, -3.08) for OROS-methylphenidate and 12.65 points (Cohen's d, -3.05) for atomoxetine; and mean changes in ADHD-RS-IV Hyperactivity-Impulsivity scores were 10.16 points (Cohen's d, -1.75) for OROS-methylphenidate and 10.68 points (Cohen's d, -1.87) for atomoxetine. In terms of parent-, teacher-, and self-ratings on behavioral symptoms, both of the two treatment groups significantly decreased on the SNAP-IV scores at the end-point, with effect sizes ranging from 0.9 to 0.96 on the Inattention subscale and from 0.61 to 0.8 on the Hyperactivity/Impulsivity subscale for OROS-methylphenidate; and from 0.51 to 0.88 on the Inattention subscale and from 0.29 to 0.57 on the Hyperactivity/Impulsivity subscale for atomoxetine. No statistically significant differences between treatment groups were observed on the outcome measures. Vomiting, somnolence, and dizziness were reported more often for atomoxetine than for OROS-methylphenidate, whereas insomnia was reported more often for OROS-methylphenidate than for atomoxetine. After 24 weeks of treatment, OROS-methylphenidate and atomoxetine had comparable efficacy in reducing core ADHD symptoms in drug-naïve children and adolescents with ADHD.

  20. Interpersonal skills development in Generation Y student nurses: a literature review.

    PubMed

    Bhana, Varshika M

    2014-12-01

    Student nurses require training in the development of the interpersonal skills that are required for therapeutic nurse-patient relationships. This training should be provided within the basic education of nurses in a higher education institution. As the birth years of Generation Y range from the early 1980s to the late 1990s this generation is of the age group that enrols in higher education institutions. The unique learning needs of this generation necessitate a review of teaching strategies used in the development of interpersonal skills. The aim of this study is to present a literature review on the significance and development of interpersonal skills in Generation Y nursing students through nursing education. Literature searches were conducted on databases-with the use of Cumulative Index of Nursing and Allied Health (CINAHL), Clinical key, PubMed and Google Scholar-using specific keywords and a timeframe of 2005 to 2013. All relevant articles were read critically. Interpersonal skills are at the core of the nurse-patient relationship. Meaningful interaction is recognised in Swanson's theory of "informed caring". Debates, case studies, role-playing, storytelling, journaling, simulations and web page links to audio and video clips are some of the teaching strategies which can develop the interpersonal skills needed for meaningful interactions. Teaching strategies embedded in the deconstruction pedagogies stimulate critical, analytical thinking through methods which complement the unique learning styles of Generation Y learners. Copyright © 2014 Elsevier Ltd. All rights reserved.

  1. Folate Metabolism Gene 5,10-Methylenetetrahydrofolate Reductase (MTHFR) Is Associated with ADHD in Myelomeningocele Patients

    PubMed Central

    Spellicy, Catherine J.; Northrup, Hope; Fletcher, Jack M.; Cirino, Paul T.; Dennis, Maureen; Morrison, Alanna C.; Martinez, Carla A.; Au, Kit Sing

    2012-01-01

    The objective of this study was to examine the relation between the 5, 10-methylenetetrahydrofolate reductase (MTHFR) gene and behaviors related to attention- deficit/hyperactivity disorder (ADHD) in individuals with myelomeningocele. The rationale for the study was twofold: folate metabolizing genes, (e.g. MTHFR), are important not only in the etiology of neural tube defects but are also critical to cognitive function; and individuals with myelomeningocele have an elevated incidence of ADHD. Here, we tested 478 individuals with myelomeningocele for attention-deficit hyperactivity disorder behavior using the Swanson Nolan Achenbach Pelham-IV ADHD rating scale. Myelomeningocele participants in this group for whom DNAs were available were genotyped for seven single nucleotide polymorphisms (SNPs) in the MTHFR gene. The SNPs were evaluated for an association with manifestation of the ADHD phenotype in children with myelomeningocele. The data show that 28.7% of myelomeningocele participants exhibit rating scale elevations consistent with ADHD; of these 70.1% had scores consistent with the predominantly inattentive subtype. In addition, we also show a positive association between the SNP rs4846049 in the 3′-untranslated region of the MTHFR gene and the attention-deficit hyperactivity disorder phenotype in myelomeningocele participants. These results lend further support to the finding that behavior related to ADHD is more prevalent in patients with myelomeningocele than in the general population. These data also indicate the potential importance of the MTHFR gene in the etiology of the ADHD phenotype. PMID:23227261

  2. Efficacy of chess training for the treatment of ADHD: A prospective, open label study.

    PubMed

    Blasco-Fontecilla, Hilario; Gonzalez-Perez, Marisa; Garcia-Lopez, Raquel; Poza-Cano, Belen; Perez-Moreno, Maria Rosario; de Leon-Martinez, Victoria; Otero-Perez, Jose

    2016-01-01

    To examine the effectiveness of playing chess as a treatment option for children with ADHD. Parents of 44 children ages 6 to 17 with a primary diagnosis of ADHD consented to take part in the study. Parents completed the Spanish version of the Swanson, Nolan and Pelham Scale for parents (SNAP-IV) and the Abbreviated Conner's Rating Scales for parents (CPRS-HI) prior to an 11-week chess-training program. We used a paired t-test to compare pre- and post-intervention outcomes, and Cohen-d calculations to measure the magnitude of the effect. The statistical significance was set at P<.05. Children with ADHD improved in both the SNAP-IV (t=6.23; degrees of freedom (df)=41; P<.001) and the CPRS-HI (t=5.39; df=33; P<.001). Our results suggest a large effect in decreasing the severity of ADHD as measured by the SNAP-IV (d=0.85) and the CPRS-HI (d=0.85). Furthermore, we found a correlation between intelligence quotient and SNAP-IV improvement (P<.05). The results of our pilot study should be interpreted with caution. This pilot project highlights the importance of carrying out larger studies with a case-control design. If our results are replicated in better designed studies, playing chess could be included within the multimodal treatment of ADHD. Copyright © 2014 SEP y SEPB. Published by Elsevier España. All rights reserved.

  3. Development and Testing of Data Mining Algorithms for Earth Observation

    NASA Technical Reports Server (NTRS)

    Glymour, Clark

    2005-01-01

    The new algorithms developed under this project included a principled procedure for classification of objects, events or circumstances according to a target variable when a very large number of potential predictor variables is available but the number of cases that can be used for training a classifier is relatively small. These "high dimensional" problems require finding a minimal set of variables -called the Markov Blanket-- sufficient for predicting the value of the target variable. An algorithm, the Markov Blanket Fan Search, was developed, implemented and tested on both simulated and real data in conjunction with a graphical model classifier, which was also implemented. Another algorithm developed and implemented in TETRAD IV for time series elaborated on work by C. Granger and N. Swanson, which in turn exploited some of our earlier work. The algorithms in question learn a linear time series model from data. Given such a time series, the simultaneous residual covariances, after factoring out time dependencies, may provide information about causal processes that occur more rapidly than the time series representation allow, so called simultaneous or contemporaneous causal processes. Working with A. Monetta, a graduate student from Italy, we produced the correct statistics for estimating the contemporaneous causal structure from time series data using the TETRAD IV suite of algorithms. Two economists, David Bessler and Kevin Hoover, have independently published applications using TETRAD style algorithms to the same purpose. These implementations and algorithmic developments were separately used in two kinds of studies of climate data: Short time series of geographically proximate climate variables predicting agricultural effects in California, and longer duration climate measurements of temperature teleconnections.

  4. ADHD-related symptoms, emotional/behavioral problems, and physical conditions in Taiwanese children with epilepsy.

    PubMed

    Tsai, Fang-Ju; Liu, Shu-Tsen; Lee, Chi-Mei; Lee, Wang-Tso; Fan, Pi-Chuan; Lin, Wei-Sheng; Chiu, Yen-Nan; Gau, Susan Shur-Fen

    2013-07-01

    Little is known about whether Asian children with epilepsy have more attention-deficit hyperactivity disorder (ADHD)-related symptoms, emotional/ behavioral problems, and physical conditions compared with those described in Western studies. The authors investigated the rates of ADHD-related symptoms, emotional/behavioral problems, and physical conditions among pediatric patients with epilepsy. We recruited 61 patients with epilepsy, aged 6-16 years, and 122 age-, sex-, and parental education-matched school controls. Data on demographics, parental reports on the Child Behavior Checklist (CBCL) and Swanson, Nolan, and Pelham, version IV scale (SNAP-IV), and medical records were collected. The average full-scale intelligence quotient of the case group was 95.8. There were 11 (18.0%), 7 (11.5%), 26 (42.6%), and 26 (42.6%) of children with epilepsy ever clinically diagnosed with developmental delay, overt ADHD symptoms, allergies reported by physicians, and behavior problems measured by the CBCL, respectively. Those children with epilepsy had more severe ADHD-related symptoms and a wider range of emotional/behavioral problems than controls (Cohen's d 0.36-0.80). The rate of potential cases of ADHD among children with epilepsy was 24.6%. A history of developmental delay predicted ADHD- related symptoms and internalizing and externalizing problems. Among children with epilepsy, a longer duration of treatment with antiepileptic drugs predicted externalizing problems, and an earlier onset of epilepsy predicted inattention and hyperactivity/impulsivity. Our findings imply that clinicians should assess physical and emotional/behavioral problems among children with epilepsy in order to provide interventions to offset possible adverse psychiatric outcomes. Copyright © 2012. Published by Elsevier B.V.

  5. GAD1 gene polymorphisms are associated with hyperactivity in Attention-Deficit/Hyperactivity Disorder.

    PubMed

    Bruxel, Estela M; Akutagava-Martins, Glaucia C; Salatino-Oliveira, Angélica; Genro, Julia P; Zeni, Cristian P; Polanczyk, Guilherme V; Chazan, Rodrigo; Schmitz, Marcelo; Rohde, Luis A; Hutz, Mara H

    2016-12-01

    Attention-Deficit/Hyperactivity Disorder (ADHD) is one of the most common neurodevelopmental disorders of childhood. Recent studies suggest a role for γ-aminobutyric acid (GABA) on ADHD hyperactive/impulsive symptoms due to behavioral disinhibition resulting from inappropriate modulation of both glutamatergic and GABAergic signaling. The glutamic acid decarboxylase (GAD1) gene encodes a key enzyme of GABA biosynthesis. The aim of the present study was to investigate the possible influence of GAD1 SNPs rs3749034 and rs11542313 on ADHD susceptibility. The clinical sample consisted of 547 families with ADHD probands recruited at the ADHD Outpatient Clinics from Hospital de Clínicas de Porto Alegre. Hyperactive/impulsive symptoms were evaluated based on parent reports from the Swanson, Nolan, and Pelham Scale-version IV (SNAP-IV). The C allele of rs11542313 was significantly overtransmitted from parents to ADHD probands (P = 0.02). Hyperactive/impulsive score was higher in rs3749034G allele (P = 0.005, Cohen's D = 0.19) and rs11542313C allele (P = 0.03; Cohen's D = 0.16) carriers. GAD1 haplotypes were also associated with higher hyperactive/impulsive scores in ADHD youths (global P-value = 0.01). In the specific haplotype test, the GC haplotype was the one with the highest hyperactive/impulsive scores (P = 0.03). Our results suggest that the GAD1 gene is associated with ADHD susceptibility, contributing particularly to the hyperactive/impulsive symptom domain. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  6. A double-blind, randomized, placebo/active controlled crossover evaluation of the efficacy and safety of Ritalin ® LA in children with attention-deficit/hyperactivity disorder in a laboratory classroom setting.

    PubMed

    Schulz, Eberhard; Fleischhaker, Christian; Hennighausen, Klaus; Heiser, Philip; Oehler, Klaus-Uwe; Linder, Martin; Haessler, Frank; Huss, Michael; Warnke, Andreas; Schmidt, Martin; Schulte-Markworth, Michael; Sieder, Christian; Klatt, Jan; Tracik, Ferenc

    2010-10-01

    The primary objective of this study was to demonstrate efficacy of Ritalin(®) LA 20 mg by showing superiority to placebo and noninferiority to Medikinet(®) Retard in a laboratory classroom setting. Secondary objectives included safety/tolerability and further efficacy parameters. A total of 147 children with attention-deficit/hyperactivity disorder (ADHD) diagnosed by the Kiddie Schedule for Affective Disorders and Schizophrenia (K-SADS) and aged 6-14 (81% males) and known to be methylphenidate (MPH) responders were enrolled in this multicenter, double-blind, randomized, placebo/active-controlled, three-period (7 days each) crossover study. The Swanson, Kotlin, Agler, M-Flynn, and Pelham (SKAMP) scale was used for efficacy ratings. The mean of SKAMP Combined ratings performed at 10:30 a.m., at 12:00 a.m., and at 1:30 p.m. was defined as the primary parameter. In all, 146 patients completed all treatment periods. Intensity and frequency of adverse events were comparable between the two formulations. Ritalin(®) LA demonstrated superiority compared to placebo (p<0.0001). The observed difference in the SKAMP scores between Ritalin(®) LA and Medikinet(®) Retard between the hours 1.5 until 4.5 did not exceed the noninferiority margin (p=0.0003); therefore, the difference is regarded as not clinically relevant. Similar results were obtained for the secondary efficacy variables. Ritalin(®) LA is an efficacious, well-tolerated treatment option for children aged 6-14 with ADHD.

  7. Computerized cognitive training in children and adolescents with attention deficit/hyperactivity disorder as add-on treatment to stimulants: feasibility study and protocol description.

    PubMed

    Rosa, Virginia de Oliveira; Schmitz, Marcelo; Moreira-Maia, Carlos Roberto; Wagner, Flavia; Londero, Igor; Bassotto, Caroline de Fraga; Moritz, Guilherme; de Souza, Caroline Dos Santos; Rohde, Luis Augusto Paim

    2017-01-01

    Cognitive training has received increasing attention as a non-pharmacological approach for the treatment of attention deficit/hyperactivity disorder (ADHD) in children and adolescents. Few studies have assessed cognitive training as add-on treatment to medication in randomized placebo controlled trials. The purpose of this preliminary study was to explore the feasibility of implementing a computerized cognitive training program for ADHD in our environment, describe its main characteristics and potential efficacy in a small pilot study. Six ADHD patients aged 10-12-years old receiving stimulants and presenting residual symptoms were enrolled in a randomized clinical trial to either a standard cognitive training program or a controlled placebo condition for 12 weeks. The primary outcome was core ADHD symptoms measured using the Swanson, Nolan and Pelham Questionnaire (SNAP-IV scale). We faced higher resistance than expected to patient enrollment due to logistic issues to attend face-to-face sessions in the hospital and to fill the requirement of medication status and absence of some comorbidities. Both groups showed decrease in parent reported ADHD symptoms without statistical difference between them. In addition, improvements on neuropsychological tests were observed in both groups - mainly on trained tasks. This protocol revealed the need for new strategies to better assess the effectiveness of cognitive training such as the need to implement the intervention in a school environment to have an assessment with more external validity. Given the small sample size of this pilot study, definitive conclusions on the effects of cognitive training as add-on treatment to stimulants would be premature.

  8. A new directly moulded patellar-tendon-bearing socket.

    PubMed

    Boot, D A; Young, N J

    1985-08-01

    Silicone rubbers and casting tapes individually have previously been used in the manufacture of sockets (Swanson, 1972; Sweitzer, 1973; Ruder, 1977; Graves, 1980; Aqualite, 1982). The authors believe that the present combination of these materials to manufacture a directly moulded socket with a complete silicone rubber lining of variable thickness has not previously been described. The new socket, after addition of the modular components, allows fitting of an aligned below-knee prosthesis within three hours. The socket (Fig. 1.) is made directly on the below-knee stump, can be completed with experience in an hour and does not require the use of specialized equipment. The socket consists of an outer supportive Scotchflex layer inside which is a lining of soft smooth biocompatible silicone rubber of deliberately variable thickness to allow pressure tolerant areas to accept more load and pressure sensitive areas to accept less load (Fig.2). The thicker areas of silicone are produced by applying carefully cut Plastazote pads to the pressure sensitive areas. The thickness and extent of the pads is individually assessed according to the estimated sensitivity of the particular area (Fig. 3). The Scotchflex socket is then manufactured directly on the below-knee stump with these pads applied. The pads are then removed prior to insertion of a semi-liquid silicone rubber. Thus, when the socket with the liquid silicone rubber is re-applied to the stump, the space produced by the pads is filled by the rubber which then sets at room temperature. In this way a layer of variable thickness is produced.(ABSTRACT TRUNCATED AT 250 WORDS)

  9. Personalized Medication Response Prediction for Attention-Deficit Hyperactivity Disorder: Learning in the Model Space vs. Learning in the Data Space

    PubMed Central

    Wong, Hin K.; Tiffin, Paul A.; Chappell, Michael J.; Nichols, Thomas E.; Welsh, Patrick R.; Doyle, Orla M.; Lopez-Kolkovska, Boryana C.; Inglis, Sarah K.; Coghill, David; Shen, Yuan; Tiño, Peter

    2017-01-01

    Attention-Deficit Hyperactive Disorder (ADHD) is one of the most common mental health disorders amongst school-aged children with an estimated prevalence of 5% in the global population (American Psychiatric Association, 2013). Stimulants, particularly methylphenidate (MPH), are the first-line option in the treatment of ADHD (Reeves and Schweitzer, 2004; Dopheide and Pliszka, 2009) and are prescribed to an increasing number of children and adolescents in the US and the UK every year (Safer et al., 1996; McCarthy et al., 2009), though recent studies suggest that this is tailing off, e.g., Holden et al. (2013). Around 70% of children demonstrate a clinically significant treatment response to stimulant medication (Spencer et al., 1996; Schachter et al., 2001; Swanson et al., 2001; Barbaresi et al., 2006). However, it is unclear which patient characteristics may moderate treatment effectiveness. As such, most existing research has focused on investigating univariate or multivariate correlations between a set of patient characteristics and the treatment outcome, with respect to dosage of one or several types of medication. The results of such studies are often contradictory and inconclusive due to a combination of small sample sizes, low-quality data, or a lack of available information on covariates. In this paper, feature extraction techniques such as latent trait analysis were applied to reduce the dimension of on a large dataset of patient characteristics, including the responses to symptom-based questionnaires, developmental health factors, demographic variables such as age and gender, and socioeconomic factors such as parental income. We introduce a Bayesian modeling approach in a “learning in the model space” framework that combines existing knowledge in the literature on factors that may potentially affect treatment response, with constraints imposed by a treatment response model. The model is personalized such that the variability among subjects is accounted for by a set of subject-specific parameters. For remission classification, this approach compares favorably with conventional methods such as support vector machines and mixed effect models on a range of performance measures. For instance, the proposed approach achieved an area under receiver operator characteristic curve of 82–84%, compared to 75–77% obtained from conventional regression or machine learning (“learning in the data space”) methods. PMID:28443027

  10. Stratigraphic sections of the Phosphoria formation in Utah, 1947-48

    USGS Publications Warehouse

    McKelvey, Vincent Ellis; Smith, L.E.; Kinney, D.M.; Huddle, J.W.; Hosford, G.F.; Sears, R.S.; Sprouse, D.P.; Steward, M.D.

    1952-01-01

    As part of a comprehensive investigation of the phosphate deposits of the western field begun in 1947, the U. S. Geological survey has measured an sampled the full thickness of the Permian Phosphoria formation and its partial correlative, the Park City formation, at many localities in Utah and other western states. Although these data will not be fully analyzed for several years, segments of the data, accompanied by little or no interpretation, will be published as preliminary reports. This report, which contains abstracts of many of the sections measured in northeastern Utah (pl. 1), is one of this series. The field and laboratory procedures adopted in these investigations are described rather fully in a companion report (McKelvey and others, 1952). A large number of people have taken part in this investigation. J. B. Collins, R. A. Gulbrandsen, R. A. Hoppin, J. A. Noel, F. W. O'Malley, O. A. Payne, J. F. Rominger, R. P. Sheldon, J. E. Smedley, and R. G. Waring participated in the description of strata and collection of samples referred to in this report. D. B. Dimick, H. A. Larsen, and T. K. Rigby assisted in the preparation of trenches and the crushing and splitting of samples in the field. The laboratory preparation of samples for chemical analysis was done in Denver, Colo., under the direction of W. P. Huleatt. Most of the chemical analyses reported herein were made for the Survey by the U. S. Bureau of Mines at the Northwest Electrodevelopment Laboratory, Albany, Oreg., under the direction of S. M. Shelton and M. L. Wright. All the samples from one locality (Brazer Canyon) were analyzed in the Chemical Laboratory of the Tennessee Valley Authority at Wilson Dam, Ala. Some of the Al2O3, Fe2O3, and loss-on-ignition analyses were made in the Trace Elements Section laboratory of the Survey in Washington, D. C., under the direction of J. C. Rabbitt by chemists I. Barlow, A Caemmerer, J. Greene, N. Guttag, and E. H. Humphrey. The spectrographic analyses were made by D. M. Mortimer, of the Bureau of Mines in Albany. Compilation of the data has been largely by R. P. Sheldon and F. D. Frieske under the supervision of R. W. Swanson. Organization of the tabular data has been largely by Anita Cozzetto.

  11. A Randomized Placebo-Controlled Double-Blind Study Evaluating the Time Course of Response to Methylphenidate Hydrochloride Extended-Release Capsules in Children with Attention-Deficit/Hyperactivity Disorder

    PubMed Central

    Greenhill, Laurence L.; Nordbrock, Earl; Connor, Daniel F.; Kollins, Scott H.; Adjei, Akwete; Childress, Ann; Stehli, Annamarie; Kupper, Robert J.

    2014-01-01

    Abstract Objective: The purpose of this study was to assess the time of onset and time course of efficacy over 12.0 hours of extended-release multilayer bead formulation of methylphenidate (MPH-MLR) compared with placebo in children 6–12 years of age with attention-deficit/hyperactivity disorder (ADHD) in a laboratory school setting. Methods: This randomized double-blind placebo-controlled study included children 6–12 years of age with ADHD. Enrolled children went through four study phases: 1) Screening period (≤4 weeks) and a 2 day medication washout period; 2) open-label period with dose initiation of MPH-MLR 15 mg daily and individual dose optimization treatment period (2–4 weeks); 3) double-blind crossover period in which participants were randomized to sequences (1 week each) of placebo and the optimized MPH-MLR dose given daily; and 4) follow-up safety call. Analog classroom time course evaluations were performed at the end of each double-blind week. The primary efficacy end-point was the mean of the on-treatment/postdose Swanson, Kotkin, Agler, M-Flynn, and Pelham (SKAMP)-Total scores over time points collected 1.0–12.0 hours after dosing. End-points were evaluated using a mixed-effects analysis of covariance. Results: The evaluable population included 20 participants. The least-squares mean postdose SKAMP-Total score was higher for placebo than for MPH-MLR (2.18 vs. 1.32, respectively; p=0.0001), indicating fewer symptoms with MPH-MLR therapy than with placebo. No difference in SKAMP-Total score between participants who received sequence 1 or sequence 2 was noted. From each of hours 1.0–12.0, least-squares mean SKAMP-Total score was significantly lower for those receiving MPH-MLR than for those receiving placebo (p≤0.0261). Neither serious adverse events nor new or unexpected safety findings were noted during the study. Conclusions: MPH-MLR showed a significant decrease in SKAMP scores compared with placebo in children with ADHD 6–12 years of age, indicating a decrease in ADHD symptoms. The estimated onset was observed within 1.0 hour, and duration was measured to 12.0 hours postdose. Trial registration: ClinicalTrials.gov Identifier: NCT01269463 PMID:25470572

  12. A 1.5-Year Follow-Up of Parent Training and Atomoxetine for Attention-Deficit/Hyperactivity Disorder Symptoms and Noncompliant/Disruptive Behavior in Autism.

    PubMed

    Arnold, L Eugene; Ober, Nicole; Aman, Michael G; Handen, Benjamin; Smith, Tristram; Pan, Xueliang; Hyman, Susan L; Hollway, Jill; Lecavalier, Luc; Page, Kristin; Rice, Robert

    2018-06-01

    To examine status of children with autism spectrum disorder (ASD) 10 months after a 34-week clinical trial of atomoxetine (ATX) and parent training (PT). In a 2 × 2 design, 128 children with ASD and attention-deficit/hyperactivity disorder (ADHD) were randomly assigned ATX, PT+placebo, PT+ATX, or placebo alone. PT was weekly for 10 weeks, and then monthly. ATX/placebo was titrated over 6 weeks [≤1.8 mg/kg/d], and then maintained until week 10. Responders continued to week 34 or nonresponse. Placebo nonresponders had a 10-week ATX open trial; ATX nonresponders were treated clinically. All continued to week 34. With no further treatment from the study, all were invited to follow-up (FU) at 1.5 years postbaseline; 94 (73%) participated. Changes from Week 34 to FU and from baseline to FU were tested by one-way analysis of variance or chi-squared test. PT versus no PT was tested by chi-squared test, Fisher's exact test, Welch's t-test, Student's t-test, and Mann-Whitney's U test. For the whole sample, the primary outcomes (parent-rated ADHD on the Swanson, Nolan, and Pelham [SNAP] scale and noncompliance on the Home Situations Questionnaire [HSQ]) deteriorated mildly from week 34 to FU, but were still substantially better than baseline (SNAP: t = 12.177, df = 93, p < 0.001; HSQ: t = 8.999, df = 93, p < 0.001). On the SNAP, 61% improved ≥30% from baseline (67% did at week 34); on noncompliance, 56% improved ≥30% from baseline (77% did at week 34). Outcomes with PT were not significantly better than without PT (SNAP p = 0.30; HSQ p = 0.27). Originally assigned treatment groups did not differ significantly. Only 34% still took ATX; 27% were taking stimulants; and 25% took no medication. The majority retained their 34-week end-of-study improvement 10 months later, even though most participants stopped ATX. For some children, ATX continuation may not be necessary for continued benefit or other drugs may be necessary. Cautious individual clinical experimentation may be justified. Twelve sessions of PT made little long-term difference. ClinicalTrials.gov Identifier: Atomoxetine, Placebo and Parent Management Training in Autism (Strattera) (NCT00844753).

  13. A New Single Nucleotide Polymorphism Database for Rainbow Trout Generated Through Whole Genome Resequencing.

    PubMed

    Gao, Guangtu; Nome, Torfinn; Pearse, Devon E; Moen, Thomas; Naish, Kerry A; Thorgaard, Gary H; Lien, Sigbjørn; Palti, Yniv

    2018-01-01

    Single-nucleotide polymorphisms (SNPs) are highly abundant markers, which are broadly distributed in animal genomes. For rainbow trout ( Oncorhynchus mykiss ), SNP discovery has been previously done through sequencing of restriction-site associated DNA (RAD) libraries, reduced representation libraries (RRL) and RNA sequencing. Recently we have performed high coverage whole genome resequencing with 61 unrelated samples, representing a wide range of rainbow trout and steelhead populations, with 49 new samples added to 12 aquaculture samples from AquaGen (Norway) that we previously used for SNP discovery. Of the 49 new samples, 11 were double-haploid lines from Washington State University (WSU) and 38 represented wild and hatchery populations from a wide range of geographic distribution and with divergent migratory phenotypes. We then mapped the sequences to the new rainbow trout reference genome assembly (GCA_002163495.1) which is based on the Swanson YY doubled haploid line. Variant calling was conducted with FreeBayes and SAMtools mpileup , followed by filtering of SNPs based on quality score, sequence complexity, read depth on the locus, and number of genotyped samples. Results from the two variant calling programs were compared and genotypes of the double haploid samples were used for detecting and filtering putative paralogous sequence variants (PSVs) and multi-sequence variants (MSVs). Overall, 30,302,087 SNPs were identified on the rainbow trout genome 29 chromosomes and 1,139,018 on unplaced scaffolds, with 4,042,723 SNPs having high minor allele frequency (MAF > 0.25). The average SNP density on the chromosomes was one SNP per 64 bp, or 15.6 SNPs per 1 kb. Results from the phylogenetic analysis that we conducted indicate that the SNP markers contain enough population-specific polymorphisms for recovering population relationships despite the small sample size used. Intra-Population polymorphism assessment revealed high level of polymorphism and heterozygosity within each population. We also provide functional annotation based on the genome position of each SNP and evaluate the use of clonal lines for filtering of PSVs and MSVs. These SNPs form a new database, which provides an important resource for a new high density SNP array design and for other SNP genotyping platforms used for genetic and genomics studies of this iconic salmonid fish species.

  14. The Lateglacial to Holocene transition as recorded by glacier fluctuations

    NASA Astrophysics Data System (ADS)

    Schindelwig, I.; Akçar, N.; Kubik, P. W.; Schlüchter, C.

    2009-04-01

    Examination of glacier associated records may contribute to a better understanding of the ice-continent-ocean-atmosphere interactions, since glacial deposits related to short-term temperature fluctuations, driven by climate change, might be preserved. Surface exposure dating (SED) of such glacial deposits can improve the chronology of climate records. The western Swiss Alps repeatedly hosted mountain glaciers during the Pleistocene, and even during the Last Glacial-Interglacial transition, with abundant stadial and interstadial transitions during the Lateglacial (e.g. Björck et al. 1998). In this study, the adjacent valleys of Belalp and Great Aletsch (catchment area is generally south facing) in the western Swiss Alps are investigated. The slow responding Great Aletsch valley glacier shows only one confirmed moraine ridge related to the Lateglacial (Egesen stadial) (Kelly et al. 2004). However, the rather fast responding Unnerbäch cirque (recent) glacier at the Belalp (a similarly exposed - and tributary - valley to the Great Aletsch valley), features 6 individual lateral-terminal moraine ridges related to Lateglacial and early Holocene times. In the Belalp valley, 22 erratic boulders from four out of six well-preserved moraines were sampled in order to establish a detailed chronological framework. From the Great Aletsch valley four samples (boulder and ice moulded bedrock) of the lateral moraine were collected for SED. Our 10Be exposure dates suggest a stabilization of the Great Aletsch moraine related to the Egesen advance in the beginning of the Younger Dryas, assuming that the ages of the oldest erratic boulders on a single moraine ridge are representative for the time of moraine stabilization (Putkonen & Swanson, 2003). According to our investigations on the right-lateral moraine and the dataset (recalculated from Kelly et al. 2004) for the left-lateral moraine, the Egesen stadial is the first preserved re-advance after the last deglaciation. In contrast, the glacier at the Belalp shows multiple advances during the Lateglacial to early Holocene. 10Be exposure age data suggest that the outer moraine ridge can be an advance older than the Egesen stadial and younger than the LGM. This is in concert with other Younger Dryas related glacial landsystems in Switzerland (reviewing the outer moraine ages e.g. Julier Pass, Ivy-Ochs et al. 1996, 2008). A large number of Lateglacial moraines have been identified and relative correlations on the basis of elevation, equilibrium line altitude (Gross et al. 1977; Maisch, 1987) and morphological characteristics have been established. Nevertheless, it remains important to refine the absolute chronology in order to put further temporal constraints on these relative frameworks. This allows the allocation of such absolutely dated deposits to distinguished cold phases (Preboreal oscillation, Younger Dryas, Aegelsee oscillation) thus underlining their potential significance in the context of regional, as well as global Lateglacial climate conditions. The 10Be exposure ages from an inner moraine ridge are in a good agreement with the recalculated previously published 10Be exposure ages from the Egesen moraines in the Alps. This suggests a synchronicity of the Egesen stadial in the European Alps at the end of the Younger Dryas cold phase. REFERENCES Björck, S., Walker, M. J.C., Cwynar, L.C., Johnson, S., Knudsen, K-L., Lowe, J. J. & Wohlfarth, B. (1998): An event stratigraphy for the Last Termination in the North Atlantic region based on the Greenland ice-core record: a proposal by the INTIMATE group. Journal of Quarternary Science, 13, 283-292. Gross, G., Kerschner, H. & Patzelt, G. (1977): Methodische Untersuchungen über die Schneegrenze in alpinen Gletschergebieten. Zeitschrift für Gletscherkunde und Glazialgeologie, 12, 223-251. Ivy-Ochs, S., Kerschner, H., Reuther, A., Preusser, F., Heine, K., Maisch, M., Kubik, P.W. & Schlüchter, C. (2008): Chronology of the last glacial cycle in the European Alps. Journal of Quaternary Science, 23, 559-573. Ivy-Ochs, S., Schlüchter, C., Kubik, P. W., Synal, H.-A., Beer, J., Kerschner, H. (1996): The exposure age of an Egesen moraine at Julier Pass, Switzerland, measured with the cosmogenic radionuclides 10Be, 26Al and 36Cl. Eclogae geol. Helv., 89, 1049-1063. Kelly, M.A., Kubik, P.W., von Blanckenburg, F. & Schlüchter, C. (2004): Surface exposure dating of the Great Aletsch Glacier Egesen moraine system, western Swiss Alps, using the cosmogenic nuclide 10Be. Journal of Quarternary Science, 19, 431-441. Maisch, M. (1987): Zur Gletschergeschichte des alpinen Spätglazials: Analyse und Interpretation von Schneegrenzdaten. Geographica Helvetica, 42, 63-71. Putkonen, J. & Swanson, T. (2003): Accuracy of cosmogenic ages for moraines. Quarternary Research, 59, 255-261.

  15. [Reconstruction of severe contracture of the first web space and wrist by incorporating pedicled retrograde flap of forearm transplantation].

    PubMed

    Chen, Jianchong; Wu, Zuhuang; Zhu, Jianxian; Huang, Yongxin; Xie, Baogen

    2011-10-01

    To summarize the therapeutic effectiveness of incorporating pedicled retrograde flap of forearm transplantation for reconstructing severe contracture of the first web space and wrist. Between November 2005 and February 2010, 26 patients with severe contracture of the first web and wrist were treated. There were 18 males and 8 females with an average age of 27 years (range, 12-45 years). The locations were the right sides in 15 cases and the left sides in 11 cases. The injury reason included hot water scald in 7 cases, explosion hurt in 5 cases, traffic accident in 3 cases, hot pressing in 5 cases, and flame burns in 6 cases. The duration of scar contracture ranged from 6 to 26 months with an average of 11 months. According to the evaluation standard by GU Yudong et al., all had severe contracture of the first web space, and concomitant injuries included adduction deformity thumb, limitation of the thumb extension and opposition function, and carpometacarpal flexion joint deformity. After scar contracture was released, the defect size ranged from 5.8 cm x 4.5 cm to 11.3 cm x 7.2 cm, which were repaired by the incorporating pedicled retrograde flap of forearm of 6.5 cm x 5.0 cm to 12.5 cm x 8.0 cm at size. The donor sites were directly sutured or repaired with skin graft. Blister and partial necrosis occurred at the distal end of the flaps in 2 cases, which were cured after dressing change. The other flaps survived and wounds healed by first intention. Incisions at donor sites healed by first intention. Twenty-six patients were followed up 6 to 24 months (mean, 15 months). The patients had functional recovery in thumb adduction and opposition at different degrees. At 6 months after operation, according to the Swanson et al. AMA system for total thumb activity, the total thumb function was improved significantly, and according to Jensen et al. measurement, the width and angle of the first web space were significantly increased, all showing significant differences (P < 0.05). Incorporating pedicled retrograde flap of forearm transplantation for repairing severe contracture of the first web space and wrist could augment the first web space and improve the wrist flexible function.

  16. Computer Vision Evidence Supporting Craniometric Alignment of Rat Brain Atlases to Streamline Expert-Guided, First-Order Migration of Hypothalamic Spatial Datasets Related to Behavioral Control

    PubMed Central

    Khan, Arshad M.; Perez, Jose G.; Wells, Claire E.; Fuentes, Olac

    2018-01-01

    The rat has arguably the most widely studied brain among all animals, with numerous reference atlases for rat brain having been published since 1946. For example, many neuroscientists have used the atlases of Paxinos and Watson (PW, first published in 1982) or Swanson (S, first published in 1992) as guides to probe or map specific rat brain structures and their connections. Despite nearly three decades of contemporaneous publication, no independent attempt has been made to establish a basic framework that allows data mapped in PW to be placed in register with S, or vice versa. Such data migration would allow scientists to accurately contextualize neuroanatomical data mapped exclusively in only one atlas with data mapped in the other. Here, we provide a tool that allows levels from any of the seven published editions of atlases comprising three distinct PW reference spaces to be aligned to atlas levels from any of the four published editions representing S reference space. This alignment is based on registration of the anteroposterior stereotaxic coordinate (z) measured from the skull landmark, Bregma (β). Atlas level alignments performed along the z axis using one-dimensional Cleveland dot plots were in general agreement with alignments obtained independently using a custom-made computer vision application that utilized the scale-invariant feature transform (SIFT) and Random Sample Consensus (RANSAC) operation to compare regions of interest in photomicrographs of Nissl-stained tissue sections from the PW and S reference spaces. We show that z-aligned point source data (unpublished hypothalamic microinjection sites) can be migrated from PW to S space to a first-order approximation in the mediolateral and dorsoventral dimensions using anisotropic scaling of the vector-formatted atlas templates, together with expert-guided relocation of obvious outliers in the migrated datasets. The migrated data can be contextualized with other datasets mapped in S space, including neuronal cell bodies, axons, and chemoarchitecture; to generate data-constrained hypotheses difficult to formulate otherwise. The alignment strategies provided in this study constitute a basic starting point for first-order, user-guided data migration between PW and S reference spaces along three dimensions that is potentially extensible to other spatial reference systems for the rat brain. PMID:29765309

  17. An Isotopic Perspective into the Magmatic Evolution and Architecture of the Rift Zones of Kīlauea Volcano

    NASA Astrophysics Data System (ADS)

    Pietruszka, A. J.; Marske, J. P.; Garcia, M. O.; Heaton, D. E.; Rhodes, M. M.

    2016-12-01

    We present Pb, Sr, and Nd isotope ratios for Kīlauea's historical rift zone lavas (n=50) to examine the magmatic evolution and architecture of the volcano's East Rift Zone (ERZ) and Southwest Rift Zone (SWRZ). Our results show that Kīlauea's historical eruptive period was preceded by the delivery of a major batch of magma from the summit reservoir to the ERZ. The timing of this intrusion, most likely in the late 17th century, was probably related to the 300-yr period of explosive eruptions that followed the formation of the modern caldera (Swanson et al., 2012; JVGR). This rift-stored magma was a component in lavas from lower ERZ (LERZ) eruptions in 1790(?), 1840, 1955, and 1960. The only other components in these LERZ lavas are related to summit lavas erupted (1) after the 1924 collapse of Halemáumáu and (2) during episodes of high fountaining at Kīlauea Iki in 1959. Thus, the intrusion of magma from the summit reservoir into the LERZ is a rare occurrence that is tied to major volcanological events. Intrusions from the summit reservoir in the 1960s likely flushed most older, stored magma from the upper ERZ (UERZ) and middle ERZ (MERZ), leaving large pockets of 1960s-era magma to serve as a dominant component in many subsequent rift lavas. An increase in the duration of pre-eruptive magma storage from the UERZ ( 0-7 yr) to the MERZ ( 0-19 yr) to the LERZ (up to 335 yr) is likely controlled by a decrease in the rate of magma supply to the more distal portions of the ERZ. Lavas from several UERZ eruptions in the 1960s and 1970s have a component of mantle-derived magma that bypassed the summit reservoir. There is no evidence for a summit bypass into the MERZ, LERZ, or the volcanically active portion of the SWRZ. These results support a recent model for Kīlauea's plumbing system (Poland et al., 2014; USGS Prof. Pap. 1801): the ERZ is connected to the deeper "South Caldera" magma body and the volcanic SWRZ is connected to the shallower Halemáumáu magma body.

  18. Acceleration methods for multi-physics compressible flow

    NASA Astrophysics Data System (ADS)

    Peles, Oren; Turkel, Eli

    2018-04-01

    In this work we investigate the Runge-Kutta (RK)/Implicit smoother scheme as a convergence accelerator for complex multi-physics flow problems including turbulent, reactive and also two-phase flows. The flows considered are subsonic, transonic and supersonic flows in complex geometries, and also can be either steady or unsteady flows. All of these problems are considered to be a very stiff. We then introduce an acceleration method for the compressible Navier-Stokes equations. We start with the multigrid method for pure subsonic flow, including reactive flows. We then add the Rossow-Swanson-Turkel RK/Implicit smoother that enables performing all these complex flow simulations with a reasonable CFL number. We next discuss the RK/Implicit smoother for time dependent problem and also for low Mach numbers. The preconditioner includes an intrinsic low Mach number treatment inside the smoother operator. We also develop a modified Roe scheme with a corresponding flux Jacobian matrix. We then give the extension of the method for real gas and reactive flow. Reactive flows are governed by a system of inhomogeneous Navier-Stokes equations with very stiff source terms. The extension of the RK/Implicit smoother requires an approximation of the source term Jacobian. The properties of the Jacobian are very important for the stability of the method. We discuss what the chemical physics theory of chemical kinetics tells about the mathematical properties of the Jacobian matrix. We focus on the implication of the Le-Chatelier's principle on the sign of the diagonal entries of the Jacobian. We present the implementation of the method for turbulent flow. We use a two RANS turbulent model - one equation model - Spalart-Allmaras and a two-equation model - k-ω SST model. The last extension is for two-phase flows with a gas as a main phase and Eulerian representation of a dispersed particles phase (EDP). We present some examples for such flow computations inside a ballistic evaluation rocket motor. The numerical examples in this work include transonic flow about a RAE2822 airfoil, about a M6 Onera wing, NACA0012 airfoil at very low Mach number, two-phase flow inside a Ballistic evaluation motor (BEM), a turbulent reactive shear layer and a time dependent Sod's tube problem.

  19. Deep volcanic tremor and magma ascent mechanism under Kilauea, Hawaii

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aki, K.; Koyanagi, R.

    1981-08-10

    Deep harmonic tremor originating at depths around 40 km under Kilauea was studied using records accumulated since 1962 at the Hawaii Volcano Observatory of the U. S. Geological Survey. The deep source of the tremor was determined by onset times and confirmed by the relative amplitude across the island-wide network of seismometers. The period of tremor was conclusively shown to be determined by the source effect and not by the path or station site effect because the period would change considerably in time but maintained uniformity across the seismic net during the tremor episode. The tremor appeared to be primarilymore » composed of P waves. We interpret the observation period and amplitude in terms of the stationary crack model of Aki et al. (1977) and find that the seismic moment rates for deep tremors are considerably larger than those for shallow-tremors suggesting mor vigorous transport for the former. We propose a kinematic source model which may be more appropriate for deep tremor. According to this model, a measurable quantity called 'reduced displacement' is directly proportional to the rate of magma flow. A systematic search for deep tremor episodes was made for the period from 1962 through 1979, and the amplitude, period, and duration of the tremor were tabulated. We then constructed a cumulative reduced-displacement plot over the 18-year period. The result shows a generally steady process which does not seem to be significantly affected by major eruptions and large earthquakes near the surface. The total magma flow estimated from the reduced displacement is however, one order of magnitude smaller than that estimated by Swanson (1972). It may be that most channels transport magma aseismically, and only those with strong barriers generate tremor.« less

  20. The impact of methylphenidate on seizure frequency and severity in children with attention-deficit-hyperactivity disorder and difficult-to-treat epilepsies.

    PubMed

    Santos, Kleber; Palmini, Andre; Radziuk, Ana L; Rotert, Rosana; Bastos, Fernanda; Booij, Linda; Fernandes, Brisa S

    2013-07-01

    Difficult-to-treat epilepsies and attention-deficit-hyperactivity disorder (ADHD) often co-occur. Because of concerns about the use of stimulants in children with this comorbidity, the impact of ADHD treatment on seizure frequency and severity is not known. This pilot study evaluated the safety and efficacy of methylphenidate in this population. After a 3 month period in which antiepileptic drugs were adjusted, 22 patients recruited from a specialist outpatient clinic for severe epilepsy (16 males, six females; mean age 11 y 2 mo, SD 3 y 2 mo) received methylphenidate for 3 months in an open label, non-controlled trial; four with generalized or multifocal (symptomatic/cryptogenic) epilepsy, one with generalized (idiopathic) epilepsy, 17 with partial (symptomatic/cryptogenic) epilepsy; five with partial seizures only, 17 with primarily or secondarily generalized seizures). Epilepsy, ADHD symptoms, and side effects were assessed using the Swanson, Nolan, and Pelham Questionnaire, the Child Behavior Checklist, the Hague Seizure Severity Scale, and the Side Effects Rating Scale. Methylphenidate significantly improved ADHD. After 3 months of treatment, 73% of patients no longer had clinically significant symptoms. Methylphenidate also reduced seizure severity (9-point median decrease on the Hague Seizure Severity Scale). Seizure frequency increased in four out of 22 patients, but only one patient withdrew from the study for this reason. Most patients experienced no major side effects. These data are among the first showing that low doses of methylphenidate are safe and effective to treat ADHD symptoms in patients with difficult-to-treat epilepsies. Randomized controlled trials are needed to replicate the findings. © The Authors. Developmental Medicine & Child Neurology © 2013 Mac Keith Press.

  1. Trace element and Nd, Sr, Pb isotope geochemistry of Kilauea Volcano, Hawai'i, near-vent eruptive products: 1983-2001

    USGS Publications Warehouse

    Thornber, Carl R.; Budahn, James R.; Ridley, W. Ian; Unruh, Daniel M.

    2003-01-01

    This open-file report serves as a repository for geochemical data referred to in U.S. Geological Survey Professional Paper 1676 (Heliker, Swanson, and Takahashi, eds., 2003), which includes multidisciplinary research papers pertaining to the first twenty years of Puu Oo Kupaianaha eruption activity. Details of eruption characteristics and nomenclature are provided in the introductory chapter of that volume (Heliker and Mattox, 2003). Geochemical relations of this data are depicted and interpreted by Thornber (2003), Thornber and others (2003a) and Thornber (2001). This report supplements Thornber and others (2003b) in which whole-rock and glass major-element data on ~1000 near-vent lava samples collected during the 1983 to 2001 eruptive interval of Kilauea Volcano, Hawai'i, are presented. Herein, we present whole-rock trace element compositions of 85 representative samples collected from January 1983 to May 2001; glass trace-element compositions of 39 Pele’s Tear (tephra) samples collected from September 1995 to September 1996, and whole-rock Nd, Sr and Pb isotopic analyses of 10 representative samples collected from September 1983 to September 1993. Thornber and others (2003b) provide a specific record of sample characteristics, location, etc., for each of the samples reported here. Spreadsheets of both reports may be integrated and sorted based upon time of formation or sample numbers. General information pertaining to the selectivity and petrologic significance of this sample suite is presented by Thornber and others (2003b). As justified in that report, this select suite of time-constrained geochemical data is suitable for constructing petrologic models of pre-eruptive magmatic processes associated with prolonged rift zone eruption of Hawaiian shield volcanoes.

  2. Atomoxetine, Parent Training, and Their Combination in Children With Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder.

    PubMed

    Handen, Benjamin L; Aman, Michael G; Arnold, L Eugene; Hyman, Susan L; Tumuluru, Rameshwari V; Lecavalier, Luc; Corbett-Dick, Patricia; Pan, Xueliang; Hollway, Jill A; Buchan-Page, Kristin A; Silverman, Laura B; Brown, Nicole V; Rice, Robert R; Hellings, Jessica; Mruzek, Daniel W; McAuliffe-Bellin, Sarah; Hurt, Elizabeth A; Ryan, Melissa M; Levato, Lynne; Smith, Tristram

    2015-11-01

    Impairments associated with attention-deficit/hyperactivity disorder (ADHD) and noncompliance are prevalent in children with autism spectrum disorder (ASD). However, ADHD response to stimulants is well below rates in typically developing children, with frequent side effects. Group studies of treatments for noncompliance are rare in ASD. We examined individual and combined-effectiveness of atomoxetine (ATX) and parent training (PT) for ADHD symptoms and noncompliance. In a 3-site, 10-week, double-blind, 2 × 2 trial of ATX and PT, 128 children (ages 5-14 years) with ASD and ADHD symptoms were randomized to ATX, ATX+PT, placebo+PT, or placebo. ATX was adjusted to optimal dose (capped at 1.8 mg/kg/day) over 6 weeks and maintained for 4 additional weeks. Nine PT sessions were provided. Primary outcome measures were the parent-rated DSM ADHD symptoms on the Swanson, Nolan and Pelham (SNAP) scale and Home Situations Questionnaire (HSQ). On the SNAP, ATX, ATX+PT and placebo+PT were each superior to placebo (effect sizes 0.57-0.98; p values of .0005, .0004, and .025, respectively). For noncompliance, ATX and ATX+PT were superior to placebo (effect sizes 0.47-0.64; p values .03 and .0028, respectively). ATX was associated with decreased appetite but was otherwise well tolerated. Both ATX and PT resulted in significant improvement on ADHD symptoms, whereas ATX (both alone and combined with PT) was associated with significant decreases on measures of noncompliance. ATX appears to have a better side effects profile than psychostimulants in the population with ASD. Atomoxetine, Placebo and Parent Management Training in Autism; http://clinicaltrials.gov/; NCT00844753. Copyright © 2015 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.

  3. The quantified EEG characteristics of responders and non-responders to long-term treatment with atomoxetine in children with attention deficit hyperactivity disorders.

    PubMed

    Chiarenza, Giuseppe Augusto; Chabot, Robert; Isenhart, Robert; Montaldi, Luciano; Chiarenza, Marco Paolo; Torto, Maria Grazia Lo; Prichep, Leslie S

    2016-06-01

    The aim of our study is to examine quantitative Electroencephalogram (QEEG) differences between ADHD patients that are responders and non-responders to long-term treatment with Atomoxetine at baseline and after 6 and 12months of treatment. Patients with attention deficit hyperactivity disorder (ADHD) received atomoxetine titrated, over 7days, from 0.5 to 1.2mg/kg/day. QEEG and Swanson, Nolan, and Pelham-IV Questionnaire (SNAP-IV) scores were recorded before treatment and after therapy. Twenty minutes of eyes closed resting EEG was recorded from 19 electrodes referenced to linked earlobes. Full frequency and narrow band spectra of two minutes of artifact-free EEG were computed as well as source localization using Variable Resolution Electrical Tomography (VARETA). Abnormalities were identified using Z-spectra relative to normative values. Patients were classified as responders, non-responders and partial responders based upon the SNAP-IV findings. At baseline, the responders showed increased absolute power in alpha and delta in frontal and temporal regions, whereas, non-responders showed increased absolute power in all frequency bands that was widely distributed. With treatment responders' absolute power values moved toward normal values, whereas, non-responders remained at baseline values. Patients with increased power in the alpha band with no evidence of alterations in the beta or theta range, might be responders to treatment with atomoxetine. Increased power in the beta band coupled with increased alpha seems to be related to non-responders and one should consider atomoxetine withdrawal, especially if there is persistence of increased alpha and beta accompanied by an increase of theta. Copyright © 2016 Elsevier B.V. All rights reserved.

  4. Deep volcanic tremor and magma ascent mechanism under Kilauea, Hawaii

    USGS Publications Warehouse

    Aki, Keiiti; Koyanagi, Robert Y

    1981-01-01

    Deep harmonic tremor originating at depths around 40 km under Kilauea was studied using records accumulated since 1962 at the Hawaii Volcano Observatory of the U.S. Geological Survey. The deep source of the tremor was determined by onset times and confirmed by the relative amplitude across the island-wide network of seismometers. The period of tremor was conclusively shown to be determined by the source effect and not by the path or station site effect because the period would change considerably in time but maintained uniformity across the seismic net during the tremor episode. The tremor appeared to be primarily composed of P waves. We interpret the observed period and amplitude in terms of the stationary crack model of Aki et al. (1977) and find that the seismic moment rates for deep tremors are considerably larger than those for shallow-tremors suggesting more vigorous transport for the former. We propose a kinematic source model which may be more appropriate for deep tremor. According to this model, a measurable quantity called ‘reduced displacement’ is directly proportional to the rate of magma flow. A systematic search for deep tremor episodes was made for the period from 1962 through 1979, and the amplitude, period, and duration of the tremor were tabulated. We then constructed a cumulative reduced-displacement plot over the 18-year period. The result shows a generally steady process which does not seem to be significantly affected by major eruptions and large earthquakes near the surface. The total magma flow estimated from the reduced displacement is however, one order of magnitude smaller than that estimated by Swanson (1972). It may be that most channels transport magma aseismically, and only those with strong barriers generate tremor.

  5. Atomoxetine, Parent Training, and Their Combination in Children With Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder

    PubMed Central

    Handen, Benjamin L.; Aman, Michael G.; Arnold, L. Eugene; Hyman, Susan L.; Tumuluru, Rameshwari V.; Lecavalier, Luc; Corbett-Dick, Patricia; Pan, Xueliang; Hollway, Jill A.; Buchan-Page, Kristin A.; Silverman, Laura B.; Brown, Nicole V.; Rice, Robert R.; Hellings, Jessica; Mruzek, Daniel W.; McAuliffe-Bellin, Sarah; Hurt, Elizabeth A.; Ryan, Melissa M.; Levato, Lynne; Smith, Tristram

    2015-01-01

    Objective Impairments associated with attention-deficit/hyperactivity disorder (ADHD) and noncompliance are prevalent in children with autism spectrum disorder (ASD). However, ADHD response to stimulants is well below rates in typically developing children, with frequent side effects. Group studies of treatments for noncompliance are rare in ASD. We examined individual and combined-effectiveness of atomoxetine (ATX) and parent training (PT) for ADHD symptoms and noncompliance. Method In a 3-site, 10-week, double-blind, 2×2 trial of ATX and PT, 128 children (ages 5–14) with ASD and ADHD symptoms were randomized to ATX, ATX+PT, placebo+PT, or placebo. ATX was adjusted to optimal dose (capped at 1.8 mg/kg/day) over 6 weeks and maintained for 4 additional weeks. Nine PT sessions were provided. Primary outcome measures were the parent-rated DSM ADHD symptoms on the Swanson, Nolan and Pelham (SNAP) scale and Home Situations Questionnaire (HSQ). Results On the SNAP, ATX, ATX+PT and placebo+PT were each superior to placebo (effect sizes 0.57–0.98), with p-values of 0.0005, 0.0004 and 0.025, respectively. For noncompliance, ATX and ATX+PT were superior to placebo (effect sizes 0.47–0.64; p values of .03 and .0028, respectively). ATX was associated with decreased appetite but otherwise well-tolerated. Conclusion Both ATX and PT resulted in significant improvement on ADHD symptoms while ATX (both alone and combined with PT) was associated with significant decreases on measures of noncompliance. ATX appears to have a better side effects profile than psychostimulants in the population with ASD. PMID:26506581

  6. Efficacy and Safety of Amphetamine Extended-Release Oral Suspension in Children with Attention-Deficit/Hyperactivity Disorder.

    PubMed

    Childress, Ann C; Wigal, Sharon B; Brams, Matthew N; Turnbow, John M; Pincus, Yulia; Belden, Heidi W; Berry, Sally A

    2018-06-01

    To determine the efficacy and safety of amphetamine extended-release oral suspension (AMPH EROS) in the treatment of attention-deficit/hyperactivity disorder (ADHD) in a dose-optimized, randomized, double-blind, parallel-group study. Boys and girls aged 6 to 12 years diagnosed with ADHD were enrolled. During a 5-week, open-label, dose-optimization phase, patients began treatment with 2.5 or 5 mg/day of AMPH EROS; doses were titrated until an optimal dose (maximum 20 mg/day) was reached. During the double-blind phase, patients were randomized to receive treatment with either their optimized dose (10-20 mg/day) of AMPH EROS or placebo for 1 week. Efficacy was assessed in a laboratory classroom setting on the final day of double-blind treatment using the Swanson, Kotkin, Agler, M-Flynn, and Pelham (SKAMP) Rating Scale and Permanent Product Measure of Performance (PERMP) test. Safety was assessed measuring adverse events (AEs) and vital signs. The study was completed by 99 patients. The primary efficacy endpoint (change from predose SKAMP-Combined score at 4 hours postdose) and secondary endpoints (change from predose SKAMP-Combined scores at 1, 2, 6, 8, 10, 12, and 13 hours postdose) were statistically significantly improved with AMPH EROS treatment versus placebo at all time points. Onset of treatment effect was present by 1 hour postdosing, the first time point measured, and duration of efficacy lasted 13 hours postdosing. PERMP data mirrored the SKAMP-Combined score data. AEs (>5%) reported during dose optimization were decreased appetite, insomnia, affect lability, upper abdominal pain, mood swings, and headache. AMPH EROS was effective in reducing symptoms of ADHD and had a rapid onset and extended duration of effect. Reported AEs were consistent with those of other extended-release amphetamine products.

  7. Predicting Adverse Drug Effects from Literature- and Database-Mined Assertions.

    PubMed

    La, Mary K; Sedykh, Alexander; Fourches, Denis; Muratov, Eugene; Tropsha, Alexander

    2018-06-06

    Given that adverse drug effects (ADEs) have led to post-market patient harm and subsequent drug withdrawal, failure of candidate agents in the drug development process, and other negative outcomes, it is essential to attempt to forecast ADEs and other relevant drug-target-effect relationships as early as possible. Current pharmacologic data sources, providing multiple complementary perspectives on the drug-target-effect paradigm, can be integrated to facilitate the inference of relationships between these entities. This study aims to identify both existing and unknown relationships between chemicals (C), protein targets (T), and ADEs (E) based on evidence in the literature. Cheminformatics and data mining approaches were employed to integrate and analyze publicly available clinical pharmacology data and literature assertions interrelating drugs, targets, and ADEs. Based on these assertions, a C-T-E relationship knowledge base was developed. Known pairwise relationships between chemicals, targets, and ADEs were collected from several pharmacological and biomedical data sources. These relationships were curated and integrated according to Swanson's paradigm to form C-T-E triangles. Missing C-E edges were then inferred as C-E relationships. Unreported associations between drugs, targets, and ADEs were inferred, and inferences were prioritized as testable hypotheses. Several C-E inferences, including testosterone → myocardial infarction, were identified using inferences based on the literature sources published prior to confirmatory case reports. Timestamping approaches confirmed the predictive ability of this inference strategy on a larger scale. The presented workflow, based on free-access databases and an association-based inference scheme, provided novel C-E relationships that have been validated post hoc in case reports. With refinement of prioritization schemes for the generated C-E inferences, this workflow may provide an effective computational method for the early detection of potential drug candidate ADEs that can be followed by targeted experimental investigations.

  8. A long noncoding RNA, lincRNA-Tnfaip3, acts as a coregulator of NF-κB to modulate inflammatory gene transcription in mouse macrophages.

    PubMed

    Ma, Shibin; Ming, Zhenping; Gong, Ai-Yu; Wang, Yang; Chen, Xiqiang; Hu, Guoku; Zhou, Rui; Shibata, Annemarie; Swanson, Patrick C; Chen, Xian-Ming

    2017-03-01

    Long intergenic noncoding RNAs (lincRNAs) are long noncoding transcripts (>200 nt) from the intergenic regions of annotated protein-coding genes. We report here that the lincRNA gene lincRNA-Tnfaip3 , located at mouse chromosome 10 proximal to the tumor necrosis factor α-induced protein 3 ( Tnfaip3 ) gene, is an early-primary response gene controlled by nuclear factor-κB (NF-κB) signaling in murine macrophages. Functionally, lincRNA- Tnfaip3 appears to mediate both the activation and repression of distinct classes of inflammatory genes in macrophages. Specifically, induction of lincRNA-Tnfaip3 is required for the transactivation of NF-κB-regulated inflammatory genes in response to bacterial LPSs stimulation. LincRNA-Tnfaip3 physically interacts with the high-mobility group box 1 (Hmgb1), assembling a NF-κB/Hmgb1/lincRNA-Tnfaip3 complex in macrophages after LPS stimulation. This resultant NF-κB/Hmgb1/lincRNA-Tnfaip3 complex can modulate Hmgb1-associated histone modifications and, ultimately, transactivation of inflammatory genes in mouse macrophages in response to microbial challenge. Therefore, our data indicate a new regulatory role of NF-κB-induced lincRNA-Tnfaip3 to act as a coactivator of NF-κB for the transcription of inflammatory genes in innate immune cells through modulation of epigenetic chromatin remodeling.-Ma, S., Ming, Z., Gong, A.-Y., Wang, Y., Chen, X., Hu, G., Zhou, R., Shibata, A., Swanson, P. C., Chen, X.-M. A long noncoding RNA, LincRNA-Tnfaip3, acts as a coregulator of NF-κB to modulate inflammatory gene transcription in mouse macrophages. © FASEB.

  9. Stratigraphic sections of the Phosphoria formation in Wyoming, 1947-48

    USGS Publications Warehouse

    McKelvey, Vincent Ellis; Smith, L.E.; Hoppin, R.A.; Armstrong, F.C.

    1952-01-01

    As part of a comprehensive investigation of the phosphate deposits of the western field begun in 1947, the U. S. Geological Survey has measured and sampled the Permian Phosphoria formation at many localities in Wyoming and adjacent states. Because these data will not be fully synthesized for many years, segments of the data, accompanied by little or no interpretation, will be published as preliminary reports as they are assembled. This report, which contains abstracts of some of the sections measured in western Wyoming (pl. 1), is one of this series. The field and laboratory procedures adopted in these investigations are described rather fully in a companion report (McKelvey and others, 1952a). Many people have taken part in this investigation. R. M. Campbell, R. A. Gulbrandsen, R. A. Harris, D. M. Larrabee, F. W. O'Malley, O. A. Payne, R. S. Sears, R. P. Sheldon, and R. A. Smart participated in the description of the strata and the collection of the samples referred to in this report. D. B. Dimick, H. A. Larsen, and T. K. Rigby assisted in the preparation of exposures and the crushing and splitting of samples in the field. The laboratory preparation of samples for chemical analysis was done in Denver, Colo., under the direction of W. P. Huleatt. Most of the P2O5 and acid-insoluble analyses were made for the Survey by the U. S. Bureau of Mines at the Northwest Electrodevelopment Laboratory, Albany, Oreg., under the direction of S. M. Shelton and M. L. Wright. Most of the Al2O3, Fe2O3, and loss-on-ignition analyses were made by the Trace Elements Section laboratory of the Survey in Washington, D. C., under the direction of J. C. Rabbitt by chemists I. Barlow, A. Caemmerer, J. Greene, F. S. Grimadli, N. Guttag, H. Levine, H. Mela, Jr., and R. G. Milkey, and most of the spectrographic reports were prepared in this laboratory by C. L. Waring. The samples from one locality (Coal Canyon) were analyzed for P2O5, Al2O3, Fe2O3, V2O5, F, loss on ignition, and acid insoluble in the Chemical Laboratory of the Tennessee Valley Authority at Wilson Dam, Alabama, and spectrographically by D. M. Mortimer, of the Bureau of Mines at Albany. Compilation of the data has been largely by R. P. Sheldon and F. D. Frieske under the supervision of R. W. Swanson. Organization of the tabular data has been largely by Anita Cozzetto.

  10. A comparison of the clinical effectiveness and cost of specialised individually delivered parent training for preschool attention-deficit/hyperactivity disorder and a generic, group-based programme: a multi-centre, randomised controlled trial of the New Forest Parenting Programme versus Incredible Years.

    PubMed

    Sonuga-Barke, Edmund J S; Barton, Joanne; Daley, David; Hutchings, Judy; Maishman, Tom; Raftery, James; Stanton, Louise; Laver-Bradbury, Cathy; Chorozoglou, Maria; Coghill, David; Little, Louisa; Ruddock, Martin; Radford, Mike; Yao, Guiqing Lily; Lee, Louise; Gould, Lisa; Shipway, Lisa; Markomichali, Pavlina; McGuirk, James; Lowe, Michelle; Perez, Elvira; Lockwood, Joanna; Thompson, Margaret J J

    2018-06-01

    The objective of this study is to compare the efficacy and cost of specialised individually delivered parent training (PT) for preschool children with attention-deficit/hyperactivity disorder (ADHD) against generic group-based PT and treatment as usual (TAU). This is a multi-centre three-arm, parallel group randomised controlled trial conducted in National Health Service Trusts. The participants included in this study were preschool children (33-54 months) fulfilling ADHD research diagnostic criteria. New Forest Parenting Programme (NFPP)-12-week individual, home-delivered ADHD PT programme; Incredible Years (IY)-12-week group-based, PT programme initially designed for children with behaviour problems were the interventions. Primary outcome-Parent ratings of child's ADHD symptoms (Swanson, Nolan & Pelham Questionnaire-SNAP-IV). Secondary outcomes-teacher ratings (SNAP-IV) and direct observations of ADHD symptoms and parent/teacher ratings of conduct problems. NFPP, IY and TAU outcomes were measured at baseline (T1) and post treatment (T2). NFPP and IY outcomes only were measured 6 months post treatment (T3). Researchers, but not therapists or parents, were blind to treatment allocation. Analysis employed mixed effect regression models (multiple imputations). Intervention and other costs were estimated using standardized approaches. NFPP and IY did not differ on parent-rated SNAP-IV, ADHD combined symptoms [mean difference - 0.009 95% CI (- 0.191, 0.173), p = 0.921] or any other measure. Small, non-significant, benefits of NFPP over TAU were seen for parent-rated SNAP-IV, ADHD combined symptoms [- 0.189 95% CI (- 0.380, 0.003), p = 0.053]. NFPP significantly reduced parent-rated conduct problems compared to TAU across scales (p values < 0.05). No significant benefits of IY over TAU were seen for parent-rated SNAP, ADHD symptoms [- 0.16 95% CI (- 0.37, 0.04), p = 0.121] or parent-rated conduct problems (p > 0.05). The cost per family of providing NFPP in the trial was significantly lower than IY (£1591 versus £2103). Although, there were no differences between NFPP and IY with regards clinical effectiveness, individually delivered NFPP cost less. However, this difference may be reduced when implemented in routine clinical practice. Clinical decisions should take into account parental preferences between delivery approaches.

  11. Efficacy and Safety of a Chewable Methylphenidate Extended-Release Tablet in Children with Attention-Deficit/Hyperactivity Disorder

    PubMed Central

    Childress, Ann; Berry, Sally A.; Belden, Heidi; Walters, Faith; Chappell, Phillip; Sherman, Nancy; Orazem, John; Palumbo, Donna

    2017-01-01

    Abstract Objective: This phase 3, laboratory classroom study assessed the efficacy and safety of methylphenidate hydrochloride extended-release chewable tablets (MPH ERCT) compared with placebo in children with attention-deficit/hyperactivity disorder (ADHD). Methods: Following a 6-week, open-label, dose-optimization period, children 6–12 years of age (n = 90) with ADHD were randomly assigned to double-blind MPH ERCT at the final optimized dose (20–60 mg/day) or placebo. After 1 week of double-blind treatment, efficacy was assessed predose and 0.75, 2, 4, 8, 10, 12, and 13 hours postdose in a laboratory classroom setting. The primary efficacy measure was the average of postdose Swanson, Kotkin, Agler, M-Flynn, and Pelham (SKAMP) Rating Scale-Combined scores, analyzed using a mixed-model, repeated-measures analysis. Secondary efficacy measures included Permanent Product Measure of Performance (PERMP) total number of problems attempted and total number of problems correct. Safety assessments included adverse event (AE) monitoring and the Columbia-Suicide Severity Rating Scale (C-SSRS). Results: MPH ERCT treatment statistically significantly reduced the average of all postdose SKAMP-Combined scores versus placebo (least-squares mean difference [95% confidence interval], −7.0 [−10.9, −3.1]; p < 0.001). Statistically significant treatment differences in SKAMP-Combined scores were observed at 2 hours postdose through 8 hours postdose (p-values <0.001). Statistically significant differences between MPH ERCT and placebo in PERMP total number of problems attempted and total number of problems correct were observed at 0.75 hours postdose through 8 hours postdose (p-values ≤0.049). Common AEs in the open-label period (≥5%) were decreased appetite, upper abdominal pain, mood swings, irritability, insomnia, upper respiratory tract infection (URTI), dysgeusia, and headache; URTI was the only AE reported by >1 subject receiving MPH ERCT in the double-blind period (placebo: URTI, contusion, wound, and initial insomnia). No suicidal ideation or behavior was reported on the C-SSRS at baseline or at any postbaseline assessment. Conclusions: MPH ERCT 20–60 mg significantly improved ADHD symptoms compared with placebo at 2 hours postdose through at least 8 hours postdose. MPH ERCT was generally safe and well tolerated, with a safety profile consistent with other MPH ER formulations. ClinicalTrials.gov Identifier: NCT01654250. www.clinicaltrials.gov/ct2/show/NCT01654250. PMID:28557548

  12. Atomoxetine hydrochloride in the treatment of children and adolescents with attention-deficit/hyperactivity disorder and comorbid oppositional defiant disorder: A placebo-controlled Italian study.

    PubMed

    Dell'Agnello, Grazia; Maschietto, Dino; Bravaccio, Carmela; Calamoneri, Filippo; Masi, Gabriele; Curatolo, Paolo; Besana, Dante; Mancini, Francesca; Rossi, Andrea; Poole, Lynne; Escobar, Rodrigo; Zuddas, Alessandro

    2009-11-01

    The primary aim of this study was to assess the efficacy of atomoxetine in improving ADHD and ODD symptoms in paediatric patients with ADHD and comorbid oppositional defiant disorder (ODD), non-responders to previous psychological intervention with parent support. This was a multicentre, randomised, placebo-controlled trial conducted in patients aged 6-15 years, with ADHD and ODD diagnosed according to the DSM-IV criteria by a structured clinical interview (K-SADS-PL). Only subjects who are non-responders to a 6-week standardized parent training were randomised to atomoxetine (up to 1.2 mg/kg/day) or placebo (in a 3:1 ratio) for the following 8-week double blind phase. Only 2 of the 156 patients enrolled for the parent support phase (92.9% of males; mean age: 9.9 years), improved after the parent training program; 139 patients were randomised for entering in the study and 137 were eligible for efficacy analysis. At the end of the randomised double blind phase, the mean changes in the Swanson, Nolan and Pelham Rating Scale-Revised (SNAP-IV) ADHD subscale were -8.1+/-9.2 and -2.0+/-4.7, respectively in the atomoxetine and in the placebo group (p<0.001 between groups); changes in the ODD subscale were -2.7+/-4.1 and -0.3+/-2.6, respectively in the two groups (p=0.001 between groups). The CGI-ADHD-S score decreased in the atomoxetine group (median change at endpoint: -1.0) compared to no changes in the placebo group (p<0.001 between groups). Statistically significant differences between groups, in favour of atomoxetine, were found in the CHIP-CE scores for risk avoidance domain, emotional comfort and individual risk avoidance subdomains. An improvement in all the subscales of Conners Parents (CPRS-R:S) and Teacher (CTRS-R:S) subscales was observed with atomoxetine, except in the cognitive problems subscale in the CTRS-R:S. Only 3 patients treated with atomoxetine discontinued the study due to adverse events. No clinically significant changes of body weight, height and vital signs were observed in both groups. Treatment with atomoxetine of children and adolescents with ADHD and ODD, who did not initially respond to parental support, was associated with improvements in symptoms of ADHD and ODD, and general health status. Atomoxetine was well tolerated.

  13. Randomized Controlled Trial of Telephone-Delivered Cognitive Behavioral Therapy for Chronic Insomnia

    PubMed Central

    Arnedt, J. Todd; Cuddihy, Leisha; Swanson, Leslie M.; Pickett, Scott; Aikens, James; Chervin, Ronald D.

    2013-01-01

    Study Objectives: To compare the efficacy of telephone-delivered cognitive-behavioral therapy for insomnia to an information pamphlet control on sleep and daytime functioning at pretreatment, posttreatment, and 12-wk follow-up. Design: Randomized controlled parallel trial. Setting: N/A. Participants: Thirty individuals with chronic insomnia (27 women, age 39.1 ± 14.4 years, insomnia duration 8.7 ± 10.7 years). Interventions: Cognitive behavioral therapy for insomnia (CBTI) delivered in up to eight weekly telephone sessions (CBTI-Phone, n = 15) versus an information pamphlet control (IPC, n = 15). Measurements and Results: Sleep/wake diary, sleep-related questionnaires (Insomnia Severity Index, Pittsburgh Sleep Quality Index, 16-item Dysfunctional Beliefs and Attitudes about Sleep), and daytime symptom assessments (fatigue, depression, anxiety, and quality of life) were completed at pretreatment, posttreatment, and 12-wk follow-up. Linear mixed models indicated that sleep/wake diary sleep efficiency and total sleep time improved significantly at posttreatment in both groups and remained stable at 12-wk follow-up. More CBTI-Phone than IPC patients showed posttreatment improvements in unhelpful sleep-related cognitions (P < 0.001) and were classified as “in remission” from insomnia at follow-up (P < 0.05). Posttreatment effect sizes on most daytime symptoms were large (Cohen d = 0.8–2.5) for CBTI-Phone patients and small to moderate (Cohen d = -0.1–0.6) for IPC patients. All CBTI-Phone patients completed posttreatment and 12-wk follow-up assessments, but three IPC patients discontinued the study. Conclusions: The findings provide preliminary support for telephone-delivered CBTI in the treatment of chronic insomnia. Future larger-scale studies with more diverse samples are warranted. Some individuals with insomnia may also benefit from pamphlet-delivered CBTI with brief telephone support. Citation: Arnedt JT; Cuddihy L; Swanson LM; Pickett S; Aikens J; Chervin RD. Randomized controlled trial of telephone-delivered cognitive behavioral therapy for chronic insomnia. SLEEP 2013;36(3):353-362. PMID:23450712

  14. Maps showing mineral resource assessment for copper and molybdenum in porphyry and stockwork deposits and for tungsten, iron, gold, copper, and silver in skarn deposits, Dillion 1 degree by 2 degrees Quadrangle, Idaho and Montana

    USGS Publications Warehouse

    Pearson, R.C.; Trautwein, C.M.; Moll, S.H.; Berger, B.R.; Hanna, W.F.; Loen, J.S.; Rowan, L.C.; Ruppel, E.T.; Segal, D.B.

    1992-01-01

    This report is one of several in the series that assess the mineral resources of the Dillon quadrangle. For the purpose of the assessment, mineral deposits· in the quadrangle that are either known or suspected from a knowledge of the geologic setting have been grou~d into 30 deposit types on the basis of mineralogy, commodity, or structural or depositional setting. The emphasis in these assessment reports is on metallic minerals, but some important nonmetallic minerals will also be assessed. Fossil fuels are beyond the scope of this investigation; phosphate and uranium have been investigated previously (Swanson, 1970; Wodzicki andKrason, 1981); and certain nonmetallic. minerals, including bulk commodities such as sand and gravel, are in large supply and thus not considered. The ·mineral resource assessment discussed in this report considers two deposit types: (1) porphyry or stockwork deposits of copper. and molybdenum (referred to generally in this report as porphyry deposits) and (2) skarn deposits of tungsten, iron, gold, copper, and silver. Combining copper and molybenum porphyry deposits into a single deposit type is believed necessary for this purpose· mainly because the two metals are found together in most .deposits in the quadrangle, a geochemical signature unique to each has not been determined, and the significant petrologic characteristics of many associated plutons are not well known, especially characterist~cs of subsurface plutons whose presence is .inferred from geophysical data. In assessing mineral resources,· we have adopted a general philosophy similar to that of Harrison and others (19S6). We attempt to identify those parts of the quadrangle that are favorable for the occurrence of mineral resources. We do not attempt to locate specific exploration targets nor to determine the quantity of reserves or resources present.

  15. Replacing Burning of Fossil Fuels with Solar Cell and Wind Energy: How Important and How Soon?

    NASA Astrophysics Data System (ADS)

    Partain, L., II; Hansen, R. T.; Hansen, S. F.; Bennett, D.; Newlands, A.

    2016-12-01

    The IPCC indicated that atmospheric CO2 rise should stop to control global climate change. CO2 is the longest lived, most problematic anthropogenic greenhouse emission from burning fossil fuel. For 2000 years atmospheric CO2 concentration remained 280 ppm until 1870, when it rose sharply and nonlinearly to 400 ppm, correlated with a 1oC global mean temperature rise. Antarctic ice core data for the past 400,000 years indicate, 80 ppm shifts in atmospheric CO2 concentrations with 10,000-30,000 year interglacial periods at 280 ppm, were between ice-age glacial periods of 75,000-100,000 years at 200 ppm. The last 12,000-year interglacial "Goldilocks" period so far spans 4 civilizations: 6000 years of Western, 4000-5000 years of Inca and Aztec and 7000-8000 years of Chinese civilizations. The UN-led 2015 Paris Agreement set a goal limiting temperature rise to 2oC to prevent devastating climate change. Unfortunately IPCC modeling found a substantial probability of a rise by 4oC or more should all current fossil fuels be burned by 2100. This would result in weather extremes, rising oceans, storm surges and temperatures where low-lying coastal regions, Pacific Islands and large equatorial regions of the world could become uninhabitable. By Swanson's Law, an empirical learning curve observation, solar cell production costs drop 50% for every 10X increase in their cumulative production. After 40 years and over 5 orders-of-magnitude cumulative production increase, solar cells currently provide over 1% of the world's electricity generating capacity at a cost competitive with electricity generated from burning fossil fuels. If their cumulative generating capacity keeps doubling every 2 years (similar to Moore's Law), energy equivalent to all the world's electricity generating capacity could be provided by solar cells by 2028. The variability of solar cell energy can be mitigated by combining it with wind power, storage, super grids, space mirrors, and demand response.

  16. Atomoxetine and Parent Training for Children With Autism and Attention-Deficit/Hyperactivity Disorder: A 24-Week Extension Study.

    PubMed

    Smith, Tristram; Aman, Michael G; Arnold, L Eugene; Silverman, Laura B; Lecavalier, Luc; Hollway, Jill; Tumuluru, Rameshwari; Hyman, Susan L; Buchan-Page, Kristin A; Hellings, Jessica; Rice, Robert R; Brown, Nicole V; Pan, Xueliang; Handen, Benjamin L

    2016-10-01

    The authors previously reported on a 2-by-2 randomized clinical trial of individual and combined treatment with atomoxetine (ATX) and parent training (PT) for attention-deficit/hyperactivity disorder (ADHD) symptoms and behavioral noncompliance in 128 5- to 14-year-old children with autism spectrum disorder. In the present report, they describe a 24-week extension of treatment responders and nonresponders. One-hundred seventeen participants from the acute trial (91%) entered the extension; 84 of these were in 2 subgroups: "treatment responders" (n = 43) from all 4 groups in the acute trial, seen monthly for 24 weeks, and "placebo nonresponders" (n = 41), treated with open-label ATX for 10 weeks. Participants originally assigned to PT continued PT during the extension; the remainder served as controls. Primary outcome measurements were the parent-rated Swanson, Nolan and Pelham ADHD scale and the Home Situations Questionnaire. Sixty percent (26 of 43) of treatment responders in the acute trial, including 68% of responders originally assigned to ATX, still met the response criteria at the end of the extension. The response rate of placebo nonresponders treated with 10-week open-label ATX was 37% (15 of 41), similar to the acute trial. Children receiving open-label ATX + PT were significantly more likely to be ADHD responders (53% versus 23%) and noncompliance responders (58% versus 14%) than those receiving open-label ATX alone. Most ATX responders maintained their responses during the extension. PT combined with ATX in the open-label trial appeared to improve ADHD and noncompliance outcomes more than ATX alone. Clinical trial registration information-Atomoxetine, Placebo and Parent Management Training in Autism (Strattera); http://clinicaltrials.gov; NCT00844753. Copyright © 2016 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.

  17. Extended-release dexmethylphenidate 30 mg/d versus 20 mg/d: duration of attention, behavior, and performance benefits in children with attention-deficit/hyperactivity disorder.

    PubMed

    Silva, Raul R; Brams, Matthew; McCague, Kevin; Pestreich, Linda; Muniz, Rafael

    2013-01-01

    This study aimed to compare the effects of dexmethylphenidate (D-MPH) extended-release (ER) 30 mg and D-MPH-ER 20 mg on attention, behavior, and performance in children with attention-deficit/hyperactivity disorder. In a randomized, double-blind, 3-period-by-3-treatment, crossover study, children aged 6 to 12 years with attention-deficit/hyperactivity disorder stabilized on methylphenidate (40-60 mg/d) or D-MPH (20-30 mg/d) received D-MPH-ER 20 mg/d, 30 mg/d, and placebo for 7 days each (final dose of each treatment period administered in a laboratory classroom). Swanson, Kotkin, Agler, M-Flynn, and Pelham (SKAMP) Combined (Attention and Deportment) rating scale and Permanent Product Measure of Performance (PERMP) math test assessments were conducted at baseline and 3, 6, 9, 10, 11, and 12 hours postdose. A total of 165 children (94 boys; mean age, 9.6 years) were randomized (162 included in intent-to-treat analyses). Significant improvements were noted for D-MPH-ER 30 mg over D-MPH-ER 20 mg at various late time points on the SKAMP scales (Combined scores at 9, 10, 11, and 12 hours postdose; Attention scores at 10, 11, and 12 hours postdose; deportment scores at 9 and 12 hours postdose). The PERMP math test-attempted and -correct scores (change from predose) were significantly higher with D-MPH-ER 30 mg than with D-MPH-ER 20 mg at 10, 11, and 12 hours postdose. Both D-MPH-ER doses were superior to placebo at all time points. D-MPH-ER 30 mg was superior to D-MPH-ER 20 mg at later time points in the day, suggesting that higher doses of D-MPH-ER may be more effective later in the day.

  18. Decline in condition of gorgonian octocorals on mesophotic reefs in the northern Gulf of Mexico: before and after the Deepwater Horizon oil spill

    NASA Astrophysics Data System (ADS)

    Etnoyer, Peter J.; Wickes, Leslie N.; Silva, Mauricio; Dubick, J. D.; Balthis, Len; Salgado, Enrique; MacDonald, Ian R.

    2016-03-01

    Hard-bottom `mesophotic' reefs along the `40-fathom' (73 m) shelf edge in the northern Gulf of Mexico were investigated for potential effects of the Deepwater Horizon (DWH) oil spill from the Macondo well in April 2010. Alabama Alps Reef, Roughtongue Reef, and Yellowtail Reef were near the well, situated 60-88 m below floating oil discharged during the DWH spill for several weeks and subject to dispersant applications. In contrast, Coral Trees Reef and Madison Swanson South Reef were far from the DWH spill site and below the slick for less than a week or not at all, respectively. The reefs were surveyed by ROV in 2010, 2011, and 2014 and compared to similar surveys conducted one and two decades earlier. Large gorgonian octocorals were present at all sites in moderate abundance including Swiftia exserta, Hypnogorgia pendula, Thesea spp., and Placogorgia spp. The gorgonians were assessed for health and condition in a before-after-control-impact (BACI) research design using still images captured from ROV video transects. Injury was modeled as a categorical response to proximity and time using logistic regression. Condition of gorgonians at sites near Macondo well declined significantly post-spill. Before the spill, injury was observed for 4-9 % of large gorgonians. After the spill, injury was observed in 38-50 % of large gorgonians. Odds of injury for sites near Macondo were 10.8 times higher post-spill, but unchanged at far sites. The majority of marked injured colonies in 2011 declined further in condition by 2014. Marked healthy colonies generally remained healthy. Background stresses to corals, including fishing activity, fishing debris, and coral predation, were noted during surveys, but do not appear to account for the decline in condition at study sites near Macondo well.

  19. Age & reproduction in three reef - dwelling serranid fishes of the northeastern Gulf of Mexico outer continental shelf: Pronotogrammus martinicensis, Hemanthias vivanus & Serranus phoebe (with preliminary observations on the Pomacentrid fish, Chromis enchrysurus)

    USGS Publications Warehouse

    Thurman, Paul E.; McBride, Richard S.; Sulak, Kenneth J.; Dennis, George D.

    2004-01-01

    Specimens of the four study species were collected during cruises to outer-continental shelf reefs of the northeastern Gulf of Mexico. Age was estimated for all serranid species using whole otoliths and C. enchrysurus ages were determined from transverse sections of sagittal otoliths. Ring structure observed on otoliths was validated as having an annual periodicity for P. martinicensis using marginal increment analysis. Ring structure on remaining species was assumed to correspond to age (years). Pronotogrammus martinicensis, H. vivanus, S. phoebe, and C. enchrysurus exhibited maximum ages of 9, 8, 5, and 11, respectively. Spatial variations in size-at-age were observed in P. martinicensis populations. Individuals inhabiting reefs in the Madison-Swanson Reserve area on the West Florida Shelf edge exhibited the fastest growth rates, while the slowest growing P. martinicensis were collected from the Alabama Alps Reef, the farthest west study reef. Pronotogrammus martinicensis and H. vivanus are both protogynous hermaphrodites. Evidence of active spawning was observed in the months from February through July for P. martinicensis, and March and May for H. vivanus. Serranus phoebe was observed to be a simultaneous hermaphroditic capable of spawning year-round. Batch fecundity estimates for P. martinicensis ranged from 149-394 oocytes per fish. Size selectivity was evident in our primary sampling method, hook and line using small tandem bait hooks. Smaller size-classes of all species examined were under-represented in our samples, hindering accurate growth modeling. Due to the protogynous nature of P. martinicensis and H. vivanus, hook and line sampling also tended to select for males. Future descriptions of the reproductive biology of both protogynous species would be more complete if less selective sampling methods could be successfully employed. The data presented here contribute to a better assessment of the fish community of the northeastern Gulf of Mexico. Little information on age and reproduction was previously available for the serranid and pomacentrid species investigated in the present study. These species are important links between both planktonic or benthic food resources and economically-valuable groupers, snappers, and amberjacks. If a catastrophic natural or anthropogenic event occurred in these outer continental shelf reef habitats, the resultant loss of these forage species would immediately impact regional fish production via the food chain. This would be particularly true for reef-resident commercial and recreational fish species that depend extensively upon a diet of small forage fish species. Recovery to a stable community, fully repopulated with small forage fish species, would require at least a decade, possibly longer if the habitat had been substantially degraded during the initial disturbance.

  20. The Link between Peer Relations, Prosocial Behavior, and ODD/ADHD Symptoms in 7-9-Year-Old Children.

    PubMed

    Paap, Muirne C S; Haraldsen, Ira R; Breivik, Kyrre; Butcher, Phillipa R; Hellem, Frøydis M; Stormark, Kjell M

    2013-01-01

    Oppositional defiant disorder (ODD) and attention-deficit/hyperactivity disorder (ADHD) are characterized by symptoms that hinder successful positive interaction with peers. The main goal of this study was to examine if the presence of symptoms of ODD and ADHD affects the relationship between positive social behavior and peer status found in 7-9-year-old children who show symptoms typical of ADHD and/or ODD. Furthermore, the possible interaction with sex was investigated. We used data collected in the first wave of The Bergen Child Study of mental health (BCS), a prospective longitudinal total population study of children's developmental and mental health. The target population consisted of children in the second to the fourth, in all public, private, and special schools in Bergen, Norway, in the fall of 2002 (N = 9430). All 79 primary schools in Bergen participated in the study. Both teacher (8809 complete cases) and parent (6253 complete cases) report were used in the analyses. ADHD and ODD scores were estimated using the Swanson Noland and Pelham rating scale version IV (SNAP-IV), and peer problems and prosocial behavior were assessed using the Strengths and Difficulties Questionnaire (SDQ). We replicated the relationship between peer problems and prosocial behavior found previously in typically developing children. Our results showed that the relationship between peer problems and prosocial behavior became weaker as the ODD symptoms increased in number and severity. For ADHD this effect was only found in the teacher report of the children. A sex effect for ODD symptoms was found only using the parent report: boys with ODD symptoms showed less prosocial behavior than girls with similar levels of ODD symptoms. Since this effect was not found using the teacher data, it may imply a situational effect (school/home) for girls with high levels of ODD. The moderator effect of ODD/ADHD was comparable for boys and girls. Our findings suggest that even if children with ADHD/ODD symptoms have the opportunity to practice their social skills in peer relationships, this is not necessarily accompanied by an increase in prosocial behavior.

  1. Efficacy, Safety, and Tolerability of an Extended-Release Orally Disintegrating Methylphenidate Tablet in Children 6-12 Years of Age with Attention-Deficit/Hyperactivity Disorder in the Laboratory Classroom Setting.

    PubMed

    Childress, Ann C; Kollins, Scott H; Cutler, Andrew J; Marraffino, Andrea; Sikes, Carolyn R

    2017-02-01

    Methylphenidate extended-release orally disintegrating tablets (MPH XR-ODTs) represent a new technology for MPH delivery. ODTs disintegrate in the mouth without water and provide a pharmacokinetic profile that is consistent with once-daily dosing. This study sought to determine the efficacy, safety, and tolerability of this novel MPH XR-ODT formulation in school-age children with attention-deficit/hyperactivity disorder (ADHD) in a laboratory classroom setting. Children aged 6-12 years with ADHD (n = 87) were enrolled in this randomized, multicenter, double-blind, placebo-controlled, parallel, laboratory classroom study. The MPH XR-ODT dose was titrated to an optimized dose during a 4-week open-label period and maintained on that dose for 1 week. Participants (n = 85) were then randomized to receive their optimized dose of MPH XR-ODT or placebo once daily for 1 week (double blind), culminating in a laboratory classroom testing day. Efficacy was evaluated using the Swanson, Kotkin, Agler, M-Flynn, and Pelham (SKAMP) Attention, Deportment, and Combined scores along with Permanent Product Measure of Performance (PERMP; Attempted and Correct) assessments. Onset and duration of drug action were also evaluated as key secondary endpoints. Safety assessments included adverse events (AEs), physical examinations, electrocardiograms (ECGs), and the Columbia Suicide Severity Rating Scale (C-SSRS). The average SKAMP-Combined score on the classroom study day was significantly better for the MPH XR-ODT group (n = 43) than for the placebo group (n = 39; p < 0.0001). The effect was evident at 1 hour and lasted through 12 hours postdose. The average SKAMP-Attention, SKAMP-Deportment, PERMP-A, and PERMP-C scores were indicative of significantly greater ADHD symptom control for the MPH XR-ODT group. The most common AEs reported were decreased appetite, upper abdominal pain, headache, insomnia, upper respiratory tract infection, affect lability, irritability, cough, and vomiting. MPH XR-ODT was effective and well tolerated for the treatment of children with ADHD in a laboratory classroom setting. Clinical Trial Registry: NCT01835548 ( ClinicalTrials.gov ).

  2. Angular and axial deformities of the legs of children.

    PubMed

    McDonough, M W

    1984-12-01

    Age is often a determining factor in establishing a treatment program for these axial and angular problems. As can be seen, the deformities of torsion are noticeable from early life. Any tibial torsion should be treated early, but an excessive medial range of motion in the infant leg with a corresponding adequate lateral range of motion of the limb may be cautiously observed. Medial femoral torsion is a normal early finding in the infant thigh. The problem becomes evident as the child matures without the corresponding reduction in femoral torsion, leading to a persistence of fetal or infantile alignment. The gait consequences are usually noticed at 4 to 8 years of age. The angular changes generally are a delayed finding noticed in stance. The bowleg may be associated with marked tibial torsion and picked up early but the Blount's patient has been traditionally definable at 2 years of age. Levin and Drennan may hasten the time of diagnosis with their radiographic criteria. Knock-knee is an alignment disturbance noticed during the early to mid-childhood years, age 4 to 8 years. The diagnosis is important, differentiating physiologic from torsion-related deformities, and treatment, if warranted, should not be delayed. Generally the earlier these problems are discovered, the more optimistic the prognosis. Since the pediatric limb is in a constant state of transition, there will be a perpetual argument as to the need or efficacy of various approaches to the problems of knock-knee and bowleg. If observation is the treatment of choice, the percentage of cases which go on to osteotomies and epiphyseal stapling will continue. For those with axial or angular deformities, degenerative arthritis of the knee may be forthcoming. Swanson, Greene, and Allis warned of problems becoming "unphysiologic." If we consider the epiphyseal malleability, not only to deformity but to correction, we can appreciate Lenoir's comment of "every day the problem goes untreated is a golden opportunity lost forever." Early, gentle conservative therapy, using splints and casting, is an approach which should be considered in appropriate early problems.

  3. Intelligibility of degraded speech and the relationship between symptoms of inattention, hyperactivity/impulsivity and language impairment in children with suspected auditory processing disorder.

    PubMed

    Ahmmed, Ansar Uddin

    2017-10-01

    To compare the sensitivity and specificity of Auditory Figure Ground sub-tests of the SCAN-3 battery, using signal to noise ratio (SNR) of +8 dB (AFG+8) and 0 dB (AFG0), in identifying auditory processing disorder (APD). A secondary objective was to evaluate any difference in auditory processing (AP) between children with symptoms of inattention versus combined sub-types of Attention Deficit Hyperactivity Disorder (ADHD). Data from 201 children, aged 6 to 16 years (mean: 10 years 6 months, SD: 2 years 8 months), who were assessed for suspected APD were reviewed retrospectively. The outcomes of the SCAN-3 APD test battery, Swanson Nolan and Pelham-IV parental rating (SNAP-IV) and Children's Communication Checklist-2 (CCC-2) were analysed. AFG0 had a sensitivity of 56.3% and specificity of 100% in identifying children performing poorly in at least two of six SCAN-3 sub-tests or one of the two questionnaires, in contrast to 42.1% and 80% respectively for AFG+8. Impaired AP was mostly associated with symptoms of ADHD and /or language impairment (LI). LI was present in 92.9% of children with ADHD symptoms. Children with symptoms of combined ADHD plus LI performed significantly poorly (p < 0.05) compared to inattention ADHD plus LI in Filtered Words (FW) sub-test, but not in the rest of the SCAN-3 sub-tests. Speech in noise tests using SNR of 0 dB is better than +8 dB in assessing APD. The better FW performance of the inattention ADHD plus LI group can be speculated to be related to known difference in activity in a neural network between different sub-types of ADHD. The findings of the study and existing literature suggest that neural networks connecting the cerebral hemispheres, basal ganglia and cerebellum are involved in APD, ADHD and LI. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Evaluation of a Two-Stage Neural Model of Glaucomatous Defect: An Approach to Reduce Test-Retest Variability

    PubMed Central

    PAN, FEI; SWANSON, WILLIAM H.; DUL, MITCHELL W.

    2006-01-01

    Purpose. The purpose of this study is to model perimetric defect and variability and identify stimulus conditions that can reduce variability while retaining good ability to detect glaucomatous defects. Methods. The two-stage neural model of Swanson et al.1 was extended to explore relations among perimetric defect, response variability, and heterogeneous glaucomatous ganglion cell damage. Predictions of the model were evaluated by testing patients with glaucoma using a standard luminance increment 0.43° in diameter and two innovative stimuli designed to tap cortical mechanisms tuned to low spatial frequencies. The innovative stimuli were a luminance-modulated Gabor stimulus (0.5 c/deg) and circular equiluminant red-green chromatic stimuli whose sizes were close to normal Ricco’s areas for the chromatic mechanism. Seventeen patients with glaucoma were each tested twice within a 2-week period. Sensitivities were measured at eight locations at eccentricities from 10° to 21° selected in terms of the retinal nerve fiber bundle patterns. Defect depth and response (test-retest) variability were compared for the innovative stimuli and the standard stimulus. Results. The model predicted that response variability in defective areas would be lower for our innovative stimuli than for the conventional perimetric stimulus with similar defect depths if detection of the chromatic and Gabor stimuli was mediated by spatial mechanisms tuned to low spatial frequencies. Experimental data were consistent with these predictions. Depth of defect was similar for all three stimuli (F = 1.67, p > 0.19). Mean response variability was lower for the chromatic stimulus than for the other stimuli (F = 5.58, p < 0.005) and was lower for the Gabor stimulus than for the standard stimulus in areas with more severe defects (t = 2.68, p < 0.005). Variability increased with defect depth for the standard and Gabor stimuli (p < 0.005) but not for the chromatic stimulus (slope less than zero). Conclusions. Use of large perimetric stimuli detected by cortical mechanisms tuned to low spatial frequencies can make it possible to lower response variability without comprising the ability to detect glaucomatous defect. PMID:16840874

  5. Evaluation of a two-stage neural model of glaucomatous defect: an approach to reduce test-retest variability.

    PubMed

    Pan, Fei; Swanson, William H; Dul, Mitchell W

    2006-07-01

    The purpose of this study is to model perimetric defect and variability and identify stimulus conditions that can reduce variability while retaining good ability to detect glaucomatous defects. The two-stage neural model of Swanson et al. was extended to explore relations among perimetric defect, response variability, and heterogeneous glaucomatous ganglion cell damage. Predictions of the model were evaluated by testing patients with glaucoma using a standard luminance increment 0.43 degrees in diameter and two innovative stimuli designed to tap cortical mechanisms tuned to low spatial frequencies. The innovative stimuli were a luminance-modulated Gabor stimulus (0.5 c/deg) and circular equiluminant red-green chromatic stimuli whose sizes were close to normal Ricco's areas for the chromatic mechanism. Seventeen patients with glaucoma were each tested twice within a 2-week period. Sensitivities were measured at eight locations at eccentricities from 10 degrees to 21 degrees selected in terms of the retinal nerve fiber bundle patterns. Defect depth and response (test-retest) variability were compared for the innovative stimuli and the standard stimulus. The model predicted that response variability in defective areas would be lower for our innovative stimuli than for the conventional perimetric stimulus with similar defect depths if detection of the chromatic and Gabor stimuli was mediated by spatial mechanisms tuned to low spatial frequencies. Experimental data were consistent with these predictions. Depth of defect was similar for all three stimuli (F = 1.67, p > 0.19). Mean response variability was lower for the chromatic stimulus than for the other stimuli (F = 5.58, p < 0.005) and was lower for the Gabor stimulus than for the standard stimulus in areas with more severe defects (t = 2.68, p < 0.005). Variability increased with defect depth for the standard and Gabor stimuli (p < 0.005) but not for the chromatic stimulus (slope less than zero). Use of large perimetric stimuli detected by cortical mechanisms tuned to low spatial frequencies can make it possible to lower response variability without comprising the ability to detect glaucomatous defect.

  6. The Link between Peer Relations, Prosocial Behavior, and ODD/ADHD Symptoms in 7–9-Year-Old Children

    PubMed Central

    Paap, Muirne C. S.; Haraldsen, Ira R.; Breivik, Kyrre; Butcher, Phillipa R.; Hellem, Frøydis M.; Stormark, Kjell M.

    2013-01-01

    Oppositional defiant disorder (ODD) and attention-deficit/hyperactivity disorder (ADHD) are characterized by symptoms that hinder successful positive interaction with peers. The main goal of this study was to examine if the presence of symptoms of ODD and ADHD affects the relationship between positive social behavior and peer status found in 7–9-year-old children who show symptoms typical of ADHD and/or ODD. Furthermore, the possible interaction with sex was investigated. We used data collected in the first wave of The Bergen Child Study of mental health (BCS), a prospective longitudinal total population study of children's developmental and mental health. The target population consisted of children in the second to the fourth, in all public, private, and special schools in Bergen, Norway, in the fall of 2002 (N = 9430). All 79 primary schools in Bergen participated in the study. Both teacher (8809 complete cases) and parent (6253 complete cases) report were used in the analyses. ADHD and ODD scores were estimated using the Swanson Noland and Pelham rating scale version IV (SNAP-IV), and peer problems and prosocial behavior were assessed using the Strengths and Difficulties Questionnaire (SDQ). We replicated the relationship between peer problems and prosocial behavior found previously in typically developing children. Our results showed that the relationship between peer problems and prosocial behavior became weaker as the ODD symptoms increased in number and severity. For ADHD this effect was only found in the teacher report of the children. A sex effect for ODD symptoms was found only using the parent report: boys with ODD symptoms showed less prosocial behavior than girls with similar levels of ODD symptoms. Since this effect was not found using the teacher data, it may imply a situational effect (school/home) for girls with high levels of ODD. The moderator effect of ODD/ADHD was comparable for boys and girls. Our findings suggest that even if children with ADHD/ODD symptoms have the opportunity to practice their social skills in peer relationships, this is not necessarily accompanied by an increase in prosocial behavior. PMID:24286065

  7. Discrimination of Thermal versus Mechanical Effects of Shock on Rock Magnetic Properties of Spherically Shocked up to 10-160 GPa Basalt and Diabase

    NASA Astrophysics Data System (ADS)

    Bezaeva, N. S.; Swanson-Hysell, N.; Tikoo, S.; Badyukov, D. D.; Kars, M. A. C.; Egli, R.; Chareev, D. A.; Fairchild, L. M.

    2016-12-01

    Understanding how shock waves generated during hypervelocity impacts affect rock magnetic properties is key for interpreting the paleomagnetic records of lunar rocks, meteorites, and cratered planetary surfaces. Laboratory simulations of impacts show that ultra-high shocks may induce substantial post-shock heating of the target material. At high pressures (>10 GPa), shock heating occurs in tandem with mechanical effects, such as grain fracturing and creation of crystallographic defects and dislocations within magnetic grains. This makes it difficult to conclude whether shock-induced changes in the rock magnetic properties of target materials are primarily associated with mechanical or thermal effects. Here we present novel experimental methods to discriminate between mechanical and thermal effects of shock on magnetic properties and illustrate it with two examples of spherically shocked terrestrial basalt and diabase [1], which were shocked to pressures of 10 to >160 GPa, and investigate possible explanations for the observed shock-induced magnetic hardening (i.e., increase in remanent coercivity Bcr). The methods consist of i) conducting extra heating experiments at temperatures resembling those experienced during high-pressure shock events on untreated equivalents of shocked rocks (with further comparison of Bcr of shocked and heated samples) and ii) quantitative comparison of high-resolution first-order reversal curve (FORC) diagrams (field step: 0.5-0.7 mT) for shocked, heated and untreated specimens. Using this approach, we demonstrated that the shock-induced coercivity hardening in our samples is predominantly due to solid-state, mechanical effects of shock rather than alteration associated with shock heating. Indeed, heating-induced changes in Bcr in the post-shock temperature range were minor. Visual inspection of FORC contours (in addition to detailed analyses) reveals a stretching of the FORC distribution of shocked sample towards higher coercivities, consistent with shock-induced hardening. However, shock does not alter the intrinsic shape of coercivity and the shape of FORC contours (apart from field scaling) while heating does, which is seen as a significant alteration of FORC contours. Reference: [1] Swanson-Hysell N. L. et al. 2014. G3 15:2039-2047.

  8. Full Life Cycle of Data Analysis with Climate Model Diagnostic Analyzer (CMDA)

    NASA Astrophysics Data System (ADS)

    Lee, S.; Zhai, C.; Pan, L.; Tang, B.; Zhang, J.; Bao, Q.; Malarout, N.

    2017-12-01

    We have developed a system that supports the full life cycle of a data analysis process, from data discovery, to data customization, to analysis, to reanalysis, to publication, and to reproduction. The system called Climate Model Diagnostic Analyzer (CMDA) is designed to demonstrate that the full life cycle of data analysis can be supported within one integrated system for climate model diagnostic evaluation with global observational and reanalysis datasets. CMDA has four subsystems that are highly integrated to support the analysis life cycle. Data System manages datasets used by CMDA analysis tools, Analysis System manages CMDA analysis tools which are all web services, Provenance System manages the meta data of CMDA datasets and the provenance of CMDA analysis history, and Recommendation System extracts knowledge from CMDA usage history and recommends datasets/analysis tools to users. These four subsystems are not only highly integrated but also easily expandable. New datasets can be easily added to Data System and scanned to be visible to the other subsystems. New analysis tools can be easily registered to be available in the Analysis System and Provenance System. With CMDA, a user can start a data analysis process by discovering datasets of relevance to their research topic using the Recommendation System. Next, the user can customize the discovered datasets for their scientific use (e.g. anomaly calculation, regridding, etc) with tools in the Analysis System. Next, the user can do their analysis with the tools (e.g. conditional sampling, time averaging, spatial averaging) in the Analysis System. Next, the user can reanalyze the datasets based on the previously stored analysis provenance in the Provenance System. Further, they can publish their analysis process and result to the Provenance System to share with other users. Finally, any user can reproduce the published analysis process and results. By supporting the full life cycle of climate data analysis, CMDA improves the research productivity and collaboration level of its user.

  9. Prognostic Analysis System and Methods of Operation

    NASA Technical Reports Server (NTRS)

    MacKey, Ryan M. E. (Inventor); Sneddon, Robert (Inventor)

    2014-01-01

    A prognostic analysis system and methods of operating the system are provided. In particular, a prognostic analysis system for the analysis of physical system health applicable to mechanical, electrical, chemical and optical systems and methods of operating the system are described herein.

  10. Stratigraphic sections of the Phosphoria formation in Idaho, 1947-48, Part I

    USGS Publications Warehouse

    McKelvey, Vincent Ellis; Davidson, D.F.; O'Malley, F. W.; Smith, L.E.; Armstrong, F.C.; Sheldon, R.P.

    1952-01-01

    The Permian Phosphoria formation of the western states contains one of the world's largest reserves of phosphate. Although previous investigations (see especially Mansfield, 1927), including reconnaissance geologic mapping and sampling, established the location of most of the important deposits and their quality of scattered localities, they were not sufficiently detailed to permit a comparison of the merits of individual deposits or an appraisal of the reserves of phosphate rock that might be available under present economic conditions. Because the growing importance of the western phosphate deposits requires a better, more detailed understanding of their distribution and quality, the Geological Survey began in 1947 a comprehensive investigation, including (1) reconnaissance geologic mapping, mostly in Montana, of areas in which the Phosphoria formation could occur but where it had not previously been looked for or found; (2) geologic mapping, mostly in Montana, at a scale no smaller than 1:62,500, of several areas known to contain the Phosphoria formation but not previously mapped except in reconnaissance fashion; (3) geologic and topographic mapping, at a scale of 1:12,000, of some of the richest, thickest, and most accessible deposits; (4) measuring, describing, and sampling all beds of the phosphatic and shaly parts, and in some places the full thickness, of the Phosphoria formation and its stratigraphic equivalents at one or two localities per township over the entire field; (5) chemical and spectrographic analysis of the samples for phosphate, fluorine, minor metals, oil, and rock-forming constituents; and (6) petrologic and geochemical studies of the rocks and minerals of the formation. These studies are designed to define the regional and local geologic structures in which the phosphate bed lie, to provide a basis for the estimation of reserves of the inferred class over the entire region, and to determine the origin of the rocks and the elements contained in them. The data collected are not of the detail required to plan actual mining operations, but it is hoped they will guide industry in the selection of individual deposits worthy of further exploration. Most of the field work contemplated as a part of this investigation is now completed. Although the data will not be compiled or published in final form for some years to come, segments of the data, accompanied by little or no interpretation, will be published as preliminary maps or reports as they are assembled. The present report is the first of a series presenting in abbreviated form the description and analyses of the beds measured and sampled at various localities in southeastern Idaho (pl. 1). Companion reports presenting segments of the data from Montana, Wyoming, and Utah (Swanson and others, 1952, and McKelvey and others, 1952a and 1952b) are being released at the same time as this report, and others are in preparation.

  11. Robustness Analysis of Integrated LPV-FDI Filters and LTI-FTC System for a Transport Aircraft

    NASA Technical Reports Server (NTRS)

    Khong, Thuan H.; Shin, Jong-Yeob

    2007-01-01

    This paper proposes an analysis framework for robustness analysis of a nonlinear dynamics system that can be represented by a polynomial linear parameter varying (PLPV) system with constant bounded uncertainty. The proposed analysis framework contains three key tools: 1) a function substitution method which can convert a nonlinear system in polynomial form into a PLPV system, 2) a matrix-based linear fractional transformation (LFT) modeling approach, which can convert a PLPV system into an LFT system with the delta block that includes key uncertainty and scheduling parameters, 3) micro-analysis, which is a well known robust analysis tool for linear systems. The proposed analysis framework is applied to evaluating the performance of the LPV-fault detection and isolation (FDI) filters of the closed-loop system of a transport aircraft in the presence of unmodeled actuator dynamics and sensor gain uncertainty. The robustness analysis results are compared with nonlinear time simulations.

  12. System of Systems Analytic Workbench - 2017

    DTIC Science & Technology

    2017-08-31

    and transitional activities with key collaborators. The tools include: System Operational Dependency Analysis/System Developmental Dependency Analysis...in the methods of the SoS-AWB involve the following: 1. System Operability Dependency Analysis (SODA)/System Development Dependency Analysis...available f. Development of standard dependencies with combinations of low-medium-high parameters Report No. SERC-2017-TR-111

  13. Expert systems in civil engineering

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kostem, C.N.; Maher, M.L.

    1986-01-01

    This book presents the papers given at a symposium on expert systems in civil engineering. Topics considered at the symposium included problem solving using expert system techniques, construction schedule analysis, decision making and risk analysis, seismic risk analysis systems, an expert system for inactive hazardous waste site characterization, an expert system for site selection, knowledge engineering, and knowledge-based expert systems in seismic analysis.

  14. Insight and Evidence Motivating the Simplification of Dual-Analysis Hybrid Systems into Single-Analysis Hybrid Systems

    NASA Technical Reports Server (NTRS)

    Todling, Ricardo; Diniz, F. L. R.; Takacs, L. L.; Suarez, M. J.

    2018-01-01

    Many hybrid data assimilation systems currently used for NWP employ some form of dual-analysis system approach. Typically a hybrid variational analysis is responsible for creating initial conditions for high-resolution forecasts, and an ensemble analysis system is responsible for creating sample perturbations used to form the flow-dependent part of the background error covariance required in the hybrid analysis component. In many of these, the two analysis components employ different methodologies, e.g., variational and ensemble Kalman filter. In such cases, it is not uncommon to have observations treated rather differently between the two analyses components; recentering of the ensemble analysis around the hybrid analysis is used to compensated for such differences. Furthermore, in many cases, the hybrid variational high-resolution system implements some type of four-dimensional approach, whereas the underlying ensemble system relies on a three-dimensional approach, which again introduces discrepancies in the overall system. Connected to these is the expectation that one can reliably estimate observation impact on forecasts issued from hybrid analyses by using an ensemble approach based on the underlying ensemble strategy of dual-analysis systems. Just the realization that the ensemble analysis makes substantially different use of observations as compared to their hybrid counterpart should serve as enough evidence of the implausibility of such expectation. This presentation assembles numerous anecdotal evidence to illustrate the fact that hybrid dual-analysis systems must, at the very minimum, strive for consistent use of the observations in both analysis sub-components. Simpler than that, this work suggests that hybrid systems can reliably be constructed without the need to employ a dual-analysis approach. In practice, the idea of relying on a single analysis system is appealing from a cost-maintenance perspective. More generally, single-analysis systems avoid contradictions such as having to choose one sub-component to generate performance diagnostics to another, possibly not fully consistent, component.

  15. 14 CFR 417.309 - Flight safety system analysis.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... system anomaly occurring and all of its effects as determined by the single failure point analysis and... termination system. (c) Single failure point. A command control system must undergo an analysis that... fault tree analysis or a failure modes effects and criticality analysis; (2) Identify all possible...

  16. 14 CFR 417.309 - Flight safety system analysis.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... system anomaly occurring and all of its effects as determined by the single failure point analysis and... termination system. (c) Single failure point. A command control system must undergo an analysis that... fault tree analysis or a failure modes effects and criticality analysis; (2) Identify all possible...

  17. 14 CFR 417.309 - Flight safety system analysis.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... system anomaly occurring and all of its effects as determined by the single failure point analysis and... termination system. (c) Single failure point. A command control system must undergo an analysis that... fault tree analysis or a failure modes effects and criticality analysis; (2) Identify all possible...

  18. 14 CFR 417.309 - Flight safety system analysis.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... system anomaly occurring and all of its effects as determined by the single failure point analysis and... termination system. (c) Single failure point. A command control system must undergo an analysis that... fault tree analysis or a failure modes effects and criticality analysis; (2) Identify all possible...

  19. 14 CFR 417.309 - Flight safety system analysis.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... system anomaly occurring and all of its effects as determined by the single failure point analysis and... termination system. (c) Single failure point. A command control system must undergo an analysis that... fault tree analysis or a failure modes effects and criticality analysis; (2) Identify all possible...

  20. Overview of NASA Langley's Systems Analysis Capabilities

    NASA Technical Reports Server (NTRS)

    Cavanaugh, Stephen; Kumar, Ajay; Brewer, Laura; Kimmel, Bill; Korte, John; Moul, Tom

    2006-01-01

    The Systems Analysis and Concepts Directorate (SACD) has been in the systems analysis business line supporting National Aeronautics and Space Administration (NASA) aeronautics, exploration, space operations and science since the 1960 s. Our current organization structure is shown in Figure 1. SACD mission can be summed up in the following statements: 1. We conduct advanced concepts for Agency decision makers and programs. 2. We provide aerospace systems analysis products such as mission architectures, advanced system concepts, system and technology trades, life cycle cost and risk analysis, system integration and pre-decisional sensitive information. 3. Our work enables informed technical, programmatic and budgetary decisions. SACD has a complement of 114 government employees and approximately 50 on-site contractors which is equally split between supporting aeronautics and exploration. SACD strives for technical excellence and creditability of the systems analysis products delivered to its customers. The Directorate office is continuously building market intelligence and working with other NASA centers and external partners to expand our business base. The Branches strive for technical excellence and credibility of our systems analysis products by seeking out existing and new partnerships that are critical for successful systems analysis. The Directorates long term goal is to grow the amount of science systems analysis business base.

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