Time-Sharing-Based Synchronization and Performance Evaluation of Color-Independent Visual-MIMO Communication.

PubMed

Kwon, Tae-Ho; Kim, Jai-Eun; Kim, Ki-Doo

2018-05-14

In the field of communication, synchronization is always an important issue. The communication between a light-emitting diode (LED) array (LEA) and a camera is known as visual multiple-input multiple-output (MIMO), for which the data transmitter and receiver must be synchronized for seamless communication. In visual-MIMO, LEDs generally have a faster data rate than the camera. Hence, we propose an effective time-sharing-based synchronization technique with its color-independent characteristics providing the key to overcome this synchronization problem in visual-MIMO communication. We also evaluated the performance of our synchronization technique by varying the distance between the LEA and camera. A graphical analysis is also presented to compare the symbol error rate (SER) at different distances.

System Synchronizes Recordings from Separated Video Cameras

NASA Technical Reports Server (NTRS)

Nail, William; Nail, William L.; Nail, Jasper M.; Le, Doung T.

2009-01-01

A system of electronic hardware and software for synchronizing recordings from multiple, physically separated video cameras is being developed, primarily for use in multiple-look-angle video production. The system, the time code used in the system, and the underlying method of synchronization upon which the design of the system is based are denoted generally by the term "Geo-TimeCode(TradeMark)." The system is embodied mostly in compact, lightweight, portable units (see figure) denoted video time-code units (VTUs) - one VTU for each video camera. The system is scalable in that any number of camera recordings can be synchronized. The estimated retail price per unit would be about $350 (in 2006 dollars). The need for this or another synchronization system external to video cameras arises because most video cameras do not include internal means for maintaining synchronization with other video cameras. Unlike prior video-camera-synchronization systems, this system does not depend on continuous cable or radio links between cameras (however, it does depend on occasional cable links lasting a few seconds). Also, whereas the time codes used in prior video-camera-synchronization systems typically repeat after 24 hours, the time code used in this system does not repeat for slightly more than 136 years; hence, this system is much better suited for long-term deployment of multiple cameras.

Molecular Testing in Multiple Synchronous Lung Adenocarcinomas: Case Report and Literature Review.

PubMed

Rafael, Oana C; Lazzaro, Richard; Hasanovic, Adnan

2016-02-01

Discovery of driver mutations in pulmonary adenocarcinoma has revolutionized the field of thoracic oncology with major impact on therapy and diagnosis. Testing for EGFR, ALK, and KRAS mutations has become part of everyday practice. We report a case with multiple synchronous primary pulmonary adenocarcinomas in a 72-year-old female with previous history of smoking. The patient presented with cough and bilateral lung ground glass opacities. A positron emission tomography/computed tomography scan showed no activity in mediastinal lymph nodes. She underwent a left upper lobe biopsy and a right upper lobe wedge resection. Pathology revealed 4 morphologically distinct adenocarcinoma foci, suggestive of synchronous primary lung tumors. Molecular testing demonstrated no mutation in the left tumor. Three different driver mutations were present in the right lung tumors: KRAS codon 12 G12D and G12V and EGFR exon 21 L858R mutation, confirming the initial histologic impression. Subsequently, left upper lobe lobectomy showed 3 additional foci of adenocarcinoma with different morphologies, suggestive of synchronous primaries as well. No additional molecular testing was performed. Synchronous pulmonary adenocarcinomas are not uncommon; however, 4 or more synchronous tumors are rare. Distinguishing multiple primary tumors from intrapulmonary metastases is a common problem in thoracic oncology with major implications for staging, prognosis, and treatment. Lung adenocarcinoma subclassification based on predominant and coexisting histologic patterns can greatly facilitate differentiation between intrapulmonary metastases and multiple synchronous tumors. Use of molecular profiling is recommended since it further increases confidence in the diagnostic workup of multiple pulmonary adenocarcinomas and helps guiding therapy. © The Author(s) 2015.

Squamous Cell Cancer of The Lung with Synchronous Renal Cell Carcinoma

PubMed Central

Ateş, İhsan; Yazıcı, Ozan; Ateş, Hale; Yazılıtaş, Doğan; Özcan, Ayşe Naz; Ağaçkıran, Yetkin; Zengin, Nurullah

2016-01-01

Coexistence of two or more primary cancers is a relatively rare case. Not with standing that the coexistence of multiple primary cancers is often discussed in the literature, there is a small number of publications concerning the coexistence of squamous cell lung carcinoma and renal cancer. In this case report, detection of both squamous cell lung carcinoma and primary renal cancer in one male patient is going to be discussed. PMID:29404140

Modulation and synchronization technique for MF-TDMA system

NASA Technical Reports Server (NTRS)

Faris, Faris; Inukai, Thomas; Sayegh, Soheil

1994-01-01

This report addresses modulation and synchronization techniques for a multi-frequency time division multiple access (MF-TDMA) system with onboard baseband processing. The types of synchronization techniques analyzed are asynchronous (conventional) TDMA, preambleless asynchronous TDMA, bit synchronous timing with a preamble, and preambleless bit synchronous timing. Among these alternatives, preambleless bit synchronous timing simplifies onboard multicarrier demultiplexer/demodulator designs (about 2:1 reduction in mass and power), requires smaller onboard buffers (10:1 to approximately 3:1 reduction in size), and provides better frame efficiency as well as lower onboard processing delay. Analysis and computer simulation illustrate that this technique can support a bit rate of up to 10 Mbit/s (or higher) with proper selection of design parameters. High bit rate transmission may require Doppler compensation and multiple phase error measurements. The recommended modulation technique for bit synchronous timing is coherent QPSK with differential encoding for the uplink and coherent QPSK for the downlink.

Suppression of anomalous synchronization and nonstationary behavior of neural network under small-world topology

NASA Astrophysics Data System (ADS)

Boaretto, B. R. R.; Budzinski, R. C.; Prado, T. L.; Kurths, J.; Lopes, S. R.

2018-05-01

It is known that neural networks under small-world topology can present anomalous synchronization and nonstationary behavior for weak coupling regimes. Here, we propose methods to suppress the anomalous synchronization and also to diminish the nonstationary behavior occurring in weakly coupled neural network under small-world topology. We consider a network of 2000 thermally sensitive identical neurons, based on the model of Hodgkin-Huxley in a small-world topology, with the probability of adding non local connection equal to p = 0 . 001. Based on experimental protocols to suppress anomalous synchronization, as well as nonstationary behavior of the neural network dynamics, we make use of (i) external stimulus (pulsed current); (ii) biologic parameters changing (neuron membrane conductance changes); and (iii) body temperature changes. Quantification analysis to evaluate phase synchronization makes use of the Kuramoto's order parameter, while recurrence quantification analysis, particularly the determinism, computed over the easily accessible mean field of network, the local field potential (LFP), is used to evaluate nonstationary states. We show that the methods proposed can control the anomalous synchronization and nonstationarity occurring for weak coupling parameter without any effect on the individual neuron dynamics, neither in the expected asymptotic synchronized states occurring for large values of the coupling parameter.

Impulsive synchronization of Markovian jumping randomly coupled neural networks with partly unknown transition probabilities via multiple integral approach.

PubMed

Chandrasekar, A; Rakkiyappan, R; Cao, Jinde

2015-10-01

This paper studies the impulsive synchronization of Markovian jumping randomly coupled neural networks with partly unknown transition probabilities via multiple integral approach. The array of neural networks are coupled in a random fashion which is governed by Bernoulli random variable. The aim of this paper is to obtain the synchronization criteria, which is suitable for both exactly known and partly unknown transition probabilities such that the coupled neural network is synchronized with mixed time-delay. The considered impulsive effects can be synchronized at partly unknown transition probabilities. Besides, a multiple integral approach is also proposed to strengthen the Markovian jumping randomly coupled neural networks with partly unknown transition probabilities. By making use of Kronecker product and some useful integral inequalities, a novel Lyapunov-Krasovskii functional was designed for handling the coupled neural network with mixed delay and then impulsive synchronization criteria are solvable in a set of linear matrix inequalities. Finally, numerical examples are presented to illustrate the effectiveness and advantages of the theoretical results. Copyright © 2015 Elsevier Ltd. All rights reserved.

Time delay and long-range connection induced synchronization transitions in Newman-Watts small-world neuronal networks.

PubMed

Qian, Yu

2014-01-01

The synchronization transitions in Newman-Watts small-world neuronal networks (SWNNs) induced by time delay τ and long-range connection (LRC) probability P have been investigated by synchronization parameter and space-time plots. Four distinct parameter regions, that is, asynchronous region, transition region, synchronous region, and oscillatory region have been discovered at certain LRC probability P = 1.0 as time delay is increased. Interestingly, desynchronization is observed in oscillatory region. More importantly, we consider the spatiotemporal patterns obtained in delayed Newman-Watts SWNNs are the competition results between long-range drivings (LRDs) and neighboring interactions. In addition, for moderate time delay, the synchronization of neuronal network can be enhanced remarkably by increasing LRC probability. Furthermore, lag synchronization has been found between weak synchronization and complete synchronization as LRC probability P is a little less than 1.0. Finally, the two necessary conditions, moderate time delay and large numbers of LRCs, are exposed explicitly for synchronization in delayed Newman-Watts SWNNs.

Time Delay and Long-Range Connection Induced Synchronization Transitions in Newman-Watts Small-World Neuronal Networks

PubMed Central

Qian, Yu

2014-01-01

The synchronization transitions in Newman-Watts small-world neuronal networks (SWNNs) induced by time delay and long-range connection (LRC) probability have been investigated by synchronization parameter and space-time plots. Four distinct parameter regions, that is, asynchronous region, transition region, synchronous region, and oscillatory region have been discovered at certain LRC probability as time delay is increased. Interestingly, desynchronization is observed in oscillatory region. More importantly, we consider the spatiotemporal patterns obtained in delayed Newman-Watts SWNNs are the competition results between long-range drivings (LRDs) and neighboring interactions. In addition, for moderate time delay, the synchronization of neuronal network can be enhanced remarkably by increasing LRC probability. Furthermore, lag synchronization has been found between weak synchronization and complete synchronization as LRC probability is a little less than 1.0. Finally, the two necessary conditions, moderate time delay and large numbers of LRCs, are exposed explicitly for synchronization in delayed Newman-Watts SWNNs. PMID:24810595

Synchronous diffuse large B-cell lymphoma of the stomach and small cell lung carcinoma: A case report.

PubMed

Li, Jia; Zhou, Changli; Liu, Wanqi; Sun, Xun; Meng, Xiangwei

2017-12-01

The synchronous occurrence of lung cancer in patients with gastric neoplasms is relatively uncommon, especially the cases of synchronous coexistence of small cell lung carcinoma and diffuse large B-cell lymphoma of the stomach. We encountered a case of synchronous primary small cell lung carcinoma and diffuse large B-cell lymphoma of the stomach. A 63-year-old patient with a 7.5 × 5.09 cm mass in the superior lobe of the right lung diagnosed with small cell lung cancer and synchronous diffuse large B-cell lymphoma of the stomach. The diseases were diagnosed by the pathological biopsy and immunohistochemical methods. As the patient received CHOP chemotherapy, pulmonary function deterioraed. Etoposide was added to the chemotherapy. However, after the first treatment, chest computed tomography showed that the mass in the superior lobe of the right lung had increased to 8.5 × 5.2 cm. This report draws attention to the fact that the treatment of synchronous tumors is a challenge. Copyright © 2017 The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved.

Speed tracking and synchronization of multiple motors using ring coupling control and adaptive sliding mode control.

PubMed

Li, Le-Bao; Sun, Ling-Ling; Zhang, Sheng-Zhou; Yang, Qing-Quan

2015-09-01

A new control approach for speed tracking and synchronization of multiple motors is developed, by incorporating an adaptive sliding mode control (ASMC) technique into a ring coupling synchronization control structure. This control approach can stabilize speed tracking of each motor and synchronize its motion with other motors' motion so that speed tracking errors and synchronization errors converge to zero. Moreover, an adaptive law is exploited to estimate the unknown bound of uncertainty, which is obtained in the sense of Lyapunov stability theorem to minimize the control effort and attenuate chattering. Performance comparisons with parallel control, relative coupling control and conventional PI control are investigated on a four-motor synchronization control system. Extensive simulation results show the effectiveness of the proposed control scheme. Copyright © 2015 ISA. Published by Elsevier Ltd. All rights reserved.

Synchronization of metronomes

NASA Astrophysics Data System (ADS)

Pantaleone, James

2002-10-01

Synchronization is a common phenomenon in physical and biological systems. We examine the synchronization of two (and more) metronomes placed on a freely moving base. The small motion of the base couples the pendulums causing synchronization. The synchronization is generally in-phase, with antiphase synchronization occurring only under special conditions. The metronome system provides a mechanical realization of the popular Kuramoto model for synchronization of biological oscillators, and is excellent for classroom demonstrations and an undergraduate physics lab.

Frequency-varying synchronous micro-vibration suppression for a MSFW with application of small-gain theorem

NASA Astrophysics Data System (ADS)

Peng, Cong; Fan, Yahong; Huang, Ziyuan; Han, Bangcheng; Fang, Jiancheng

2017-01-01

This paper presents a novel synchronous micro-vibration suppression method on the basis of the small gain theorem to reduce the frequency-varying synchronous micro-vibration forces for a magnetically suspended flywheel (MSFW). The proposed synchronous micro-vibration suppression method not only eliminates the synchronous current fluctuations to force the rotor spinning around the inertia axis, but also considers the compensation caused by the displacement stiffness in the permanent-magnet (PM)-biased magnetic bearings. Moreover, the stability of the proposed control system is exactly analyzed by using small gain theorem. The effectiveness of the proposed micro-vibration suppression method is demonstrated via the direct measurement of the disturbance forces for a MSFW. The main merit of the proposed method is that it provides a simple and practical method in suppressing the frequency varying micro-vibration forces and preserving the nominal performance of the baseline control system.

Image synchronization for 3D application using the NanEye sensor

NASA Astrophysics Data System (ADS)

Sousa, Ricardo M.; Wäny, Martin; Santos, Pedro; Dias, Morgado

2015-03-01

Based on Awaiba's NanEye CMOS image sensor family and a FPGA platform with USB3 interface, the aim of this paper is to demonstrate a novel technique to perfectly synchronize up to 8 individual self-timed cameras. Minimal form factor self-timed camera modules of 1 mm x 1 mm or smaller do not generally allow external synchronization. However, for stereo vision or 3D reconstruction with multiple cameras as well as for applications requiring pulsed illumination it is required to synchronize multiple cameras. In this work, the challenge to synchronize multiple self-timed cameras with only 4 wire interface has been solved by adaptively regulating the power supply for each of the cameras to synchronize their frame rate and frame phase. To that effect, a control core was created to constantly monitor the operating frequency of each camera by measuring the line period in each frame based on a well-defined sampling signal. The frequency is adjusted by varying the voltage level applied to the sensor based on the error between the measured line period and the desired line period. To ensure phase synchronization between frames of multiple cameras, a Master-Slave interface was implemented. A single camera is defined as the Master entity, with its operating frequency being controlled directly through a PC based interface. The remaining cameras are setup in Slave mode and are interfaced directly with the Master camera control module. This enables the remaining cameras to monitor its line and frame period and adjust their own to achieve phase and frequency synchronization. The result of this work will allow the realization of smaller than 3mm diameter 3D stereo vision equipment in medical endoscopic context, such as endoscopic surgical robotic or micro invasive surgery.

Magnesium Object Manager Sandbox, A More Effective Sandbox Method for Windows 7

DTIC Science & Technology

2012-03-01

keys, synchronization primitives , etc.). The object body is specific to, and the same for, each object type; it contains information common to each...the Object Directory Specific Rights Synchronization Object (Event, Mutex, Semaphore , Timer) Synchronization objects allow multiple threads to... Synchronization Object Specific Rights . . . . . . . . . . . . . . . . . . . . . 19 2.5 File Object Specific Rights

Synchronizing data from irregularly sampled sensors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Uluyol, Onder

A system and method include receiving a set of sampled measurements for each of multiple sensors, wherein the sampled measurements are at irregular intervals or different rates, re-sampling the sampled measurements of each of the multiple sensors at a higher rate than one of the sensor's set of sampled measurements, and synchronizing the sampled measurements of each of the multiple sensors.

INTERDISCIPLINARY PHYSICS AND RELATED AREAS OF SCIENCE AND TECHNOLOGY: Synchronization in Complex Networks with Multiple Connections

NASA Astrophysics Data System (ADS)

Wu, Qing-Chu; Fu, Xin-Chu; Sun, Wei-Gang

2010-01-01

In this paper a class of networks with multiple connections are discussed. The multiple connections include two different types of links between nodes in complex networks. For this new model, we give a simple generating procedure. Furthermore, we investigate dynamical synchronization behavior in a delayed two-layer network, giving corresponding theoretical analysis and numerical examples.

Emergent patterns in interacting neuronal sub-populations

NASA Astrophysics Data System (ADS)

Kamal, Neeraj Kumar; Sinha, Sudeshna

2015-05-01

We investigate an ensemble of coupled model neurons, consisting of groups of varying sizes and intrinsic dynamics, ranging from periodic to chaotic, where the inter-group coupling interaction is effectively like a dynamic signal from a different sub-population. We observe that the minority group can significantly influence the majority group. For instance, when a small chaotic group is coupled to a large periodic group, the chaotic group de-synchronizes. However, counter-intuitively, when a small periodic group couples strongly to a large chaotic group, it leads to complete synchronization in the majority chaotic population, which also spikes at the frequency of the small periodic group. It then appears that the small group of periodic neurons can act like a pacemaker for the whole network. Further, we report the existence of varied clustering patterns, ranging from sets of synchronized clusters to anti-phase clusters, governed by the interplay of the relative sizes and dynamics of the sub-populations. So these results have relevance in understanding how a group can influence the synchrony of another group of dynamically different elements, reminiscent of event-related synchronization/de-synchronization in complex networks.

Decentralized finite-time attitude synchronization for multiple rigid spacecraft via a novel disturbance observer.

PubMed

Zong, Qun; Shao, Shikai

2016-11-01

This paper investigates decentralized finite-time attitude synchronization for a group of rigid spacecraft by using quaternion with the consideration of environmental disturbances, inertia uncertainties and actuator saturation. Nonsingular terminal sliding mode (TSM) is used for controller design. Firstly, a theorem is proven that there always exists a kind of TSM that converges faster than fast terminal sliding mode (FTSM) for quaternion-descripted attitude control system. Controller with this kind of TSM has faster convergence and reduced computation than FTSM controller. Then, combining with an adaptive parameter estimation strategy, a novel terminal sliding mode disturbance observer is proposed. The proposed disturbance observer needs no upper bound information of the lumped uncertainties or their derivatives. On the basis of undirected topology and the disturbance observer, decentralized attitude synchronization control laws are designed and all attitude errors are ensured to converge to small regions in finite time. As for actuator saturation problem, an auxiliary variable is introduced and accommodated by the disturbance observer. Finally, simulation results are given and the effectiveness of the proposed control scheme is testified. Copyright © 2016. Published by Elsevier Ltd.

Analysis of the Multiple-Solution Response of a Flexible Rotor Supported on Non-Linear Squeeze Film Dampers

NASA Astrophysics Data System (ADS)

ZHU, C. S.; ROBB, D. A.; EWINS, D. J.

2002-05-01

The multiple-solution response of rotors supported on squeeze film dampers is a typical non-linear phenomenon. The behaviour of the multiple-solution response in a flexible rotor supported on two identical squeeze film dampers with centralizing springs is studied by three methods: synchronous circular centred-orbit motion solution, numerical integration method and slow acceleration method using the assumption of a short bearing and cavitated oil film; the differences of computational results obtained by the three different methods are compared in this paper. It is shown that there are three basic forms for the multiple-solution response in the flexible rotor system supported on the squeeze film dampers, which are the resonant, isolated bifurcation and swallowtail bifurcation multiple solutions. In the multiple-solution speed regions, the rotor motion may be subsynchronous, super-subsynchronous, almost-periodic and even chaotic, besides synchronous circular centred, even if the gravity effect is not considered. The assumption of synchronous circular centred-orbit motion for the journal and rotor around the static deflection line can be used only in some special cases; the steady state numerical integration method is very useful, but time consuming. Using the slow acceleration method, not only can the multiple-solution speed regions be detected, but also the non-synchronous response regions.

Excitement and synchronization of small-world neuronal networks with short-term synaptic plasticity.

PubMed

Han, Fang; Wiercigroch, Marian; Fang, Jian-An; Wang, Zhijie

2011-10-01

Excitement and synchronization of electrically and chemically coupled Newman-Watts (NW) small-world neuronal networks with a short-term synaptic plasticity described by a modified Oja learning rule are investigated. For each type of neuronal network, the variation properties of synaptic weights are examined first. Then the effects of the learning rate, the coupling strength and the shortcut-adding probability on excitement and synchronization of the neuronal network are studied. It is shown that the synaptic learning suppresses the over-excitement, helps synchronization for the electrically coupled network but impairs synchronization for the chemically coupled one. Both the introduction of shortcuts and the increase of the coupling strength improve synchronization and they are helpful in increasing the excitement for the chemically coupled network, but have little effect on the excitement of the electrically coupled one.

Global synchronization of memristive neural networks subject to random disturbances via distributed pinning control.

PubMed

Guo, Zhenyuan; Yang, Shaofu; Wang, Jun

2016-12-01

This paper presents theoretical results on global exponential synchronization of multiple memristive neural networks in the presence of external noise by means of two types of distributed pinning control. The multiple memristive neural networks are coupled in a general structure via a nonlinear function, which consists of a linear diffusive term and a discontinuous sign term. A pinning impulsive control law is introduced in the coupled system to synchronize all neural networks. Sufficient conditions are derived for ascertaining global exponential synchronization in mean square. In addition, a pinning adaptive control law is developed to achieve global exponential synchronization in mean square. Both pinning control laws utilize only partial state information received from the neighborhood of the controlled neural network. Simulation results are presented to substantiate the theoretical results. Copyright © 2016 Elsevier Ltd. All rights reserved.

Adaptative synchronization in multi-output fractional-order complex dynamical networks and secure communications

NASA Astrophysics Data System (ADS)

Mata-Machuca, Juan L.; Aguilar-López, Ricardo

2018-01-01

This work deals with the adaptative synchronization of complex dynamical networks with fractional-order nodes and its application in secure communications employing chaotic parameter modulation. The complex network is composed of multiple fractional-order systems with mismatch parameters and the coupling functions are given to realize the network synchronization. We introduce a fractional algebraic synchronizability condition (FASC) and a fractional algebraic identifiability condition (FAIC) which are used to know if the synchronization and parameters estimation problems can be solved. To overcome these problems, an adaptative synchronization methodology is designed; the strategy consists in proposing multiple receiver systems which tend to follow asymptotically the uncertain transmitters systems. The coupling functions and parameters of the receiver systems are adjusted continually according to a convenient sigmoid-like adaptative controller (SLAC), until the measurable output errors converge to zero, hence, synchronization between transmitter and receivers is achieved and message signals are recovered. Indeed, the stability analysis of the synchronization error is based on the fractional Lyapunov direct method. Finally, numerical results corroborate the satisfactory performance of the proposed scheme by means of the synchronization of a complex network consisting of several fractional-order unified chaotic systems.

SPEEDES - A multiple-synchronization environment for parallel discrete-event simulation

NASA Technical Reports Server (NTRS)

Steinman, Jeff S.

1992-01-01

Synchronous Parallel Environment for Emulation and Discrete-Event Simulation (SPEEDES) is a unified parallel simulation environment. It supports multiple-synchronization protocols without requiring users to recompile their code. When a SPEEDES simulation runs on one node, all the extra parallel overhead is removed automatically at run time. When the same executable runs in parallel, the user preselects the synchronization algorithm from a list of options. SPEEDES currently runs on UNIX networks and on the California Institute of Technology/Jet Propulsion Laboratory Mark III Hypercube. SPEEDES also supports interactive simulations. Featured in the SPEEDES environment is a new parallel synchronization approach called Breathing Time Buckets. This algorithm uses some of the conservative techniques found in Time Bucket synchronization, along with the optimism that characterizes the Time Warp approach. A mathematical model derived from first principles predicts the performance of Breathing Time Buckets. Along with the Breathing Time Buckets algorithm, this paper discusses the rules for processing events in SPEEDES, describes the implementation of various other synchronization protocols supported by SPEEDES, describes some new ones for the future, discusses interactive simulations, and then gives some performance results.

Adaptive Digital Signature Design and Short-Data-Record Adaptive Filtering

DTIC Science & Technology

2008-04-01

rate BPSK binary phase shift keying CA − CFAR cell averaging− constant false alarm rate CDMA code − division multiple − access CFAR constant false...Cotae, “Spreading sequence design for multiple cell synchronous DS-CDMA systems under total weighted squared correlation criterion,” EURASIP Journal...415-428, Mar. 2002. [6] P. Cotae, “Spreading sequence design for multiple cell synchronous DS-CDMA systems under total weighted squared correlation

Pedagogic Strategies Supporting the Use of Synchronous Audiographic Conferencing: A Review of the Literature

ERIC Educational Resources Information Center

de Freitas, Sara; Neumann, Tim

2009-01-01

Synchronous audiographic conferencing (SAC) refers to a combination of technologies for real-time communication and interaction using multiple media and modes. With an increasing institutional uptake of SAC, users require an understanding of the complex interrelations of multiple media in learning scenarios in order to support pedagogic-driven…

Synchronous occurrence of prostate carcinoma and multiple myeloma: a case report.

PubMed

Sehgal, Tushar; Sharma, Sudha; Naseem, Shano; Varma, Neelam; Das, Ashim; Sharma, S C

2014-09-01

We describe a rare case of metastatic prostate cancer to bone marrow and synchronous multiple myeloma as the second malignant disease. Various diagnostic procedures, including cytomorphology and immunohistochemistry analyses together contributed to the detection of metastasis of prostate cancer and synchronous plasma cell proliferation in the bone marrow. The association between these two disorders is poorly understood however, some studies show that bone marrow microenvironment may play a crucial role. The need for further research in this regard is required to unfold this fascinating association.

Elliptical multi-sun-synchronous orbits for Mars exploration

NASA Astrophysics Data System (ADS)

Circi, Christian; Ortore, Emiliano; Bunkheila, Federico; Ulivieri, Carlo

2012-11-01

The multi-sun-synchronous orbits allow cycles of observation of the same area in which solar illumination repetitively changes according to the value of the orbit elements and returns to the initial condition after a temporal interval multiple of the repetition of observation. This paper generalizes the concept of multi-sun-synchronous orbits, whose classical sun-synchronous orbits represent particular solutions, taking into consideration the elliptical case. The feasibility of using this typology of orbits, referred to as elliptical periodic multi-sun-synchronous orbits, has been investigated for the exploration of Mars and particular solutions have been selected. Such solutions considerably reduce the manoeuvre of velocity variation at the end of the interplanetary transfer with respect to the case of a target circular orbit around Mars. They are based on the use of quasi-critical inclinations in order to minimize the apsidal line motion and thus reduce orbit maintenance costs. Moreover, in the case of high eccentricities, the argument of pericentre may be set in order to obtain, around the apocentre, a condition of quasi-synchronism with the planet (the footprint of the probe on the surface presents a small shift with respect to a fixed point on the Martian surface). The low altitude of pericentre allows observation of the planet at a higher spatial resolution, while the orbit arc around the apocentre may be used to observe Mars with a wide spatial coverage in quasi-stationary conditions. This latter characteristic is useful for analysing atmospheric and meteorological phenomena and it allows for most of the orbital period a link between a rover on the surface of Mars and a probe orbiting around the planet.

Equilibrium points and associated periodic orbits in the gravity of binary asteroid systems: (66391) 1999 KW4 as an example

NASA Astrophysics Data System (ADS)

Shi, Yu; Wang, Yue; Xu, Shijie

2018-04-01

The motion of a massless particle in the gravity of a binary asteroid system, referred as the restricted full three-body problem (RF3BP), is fundamental, not only for the evolution of the binary system, but also for the design of relevant space missions. In this paper, equilibrium points and associated periodic orbit families in the gravity of a binary system are investigated, with the binary (66391) 1999 KW4 as an example. The polyhedron shape model is used to describe irregular shapes and corresponding gravity fields of the primary and secondary of (66391) 1999 KW4, which is more accurate than the ellipsoid shape model in previous studies and provides a high-fidelity representation of the gravitational environment. Both of the synchronous and non-synchronous states of the binary system are considered. For the synchronous binary system, the equilibrium points and their stability are determined, and periodic orbit families emanating from each equilibrium point are generated by using the shooting (multiple shooting) method and the homotopy method, where the homotopy function connects the circular restricted three-body problem and RF3BP. In the non-synchronous binary system, trajectories of equivalent equilibrium points are calculated, and the associated periodic orbits are obtained by using the homotopy method, where the homotopy function connects the synchronous and non-synchronous systems. Although only the binary (66391) 1999 KW4 is considered, our methods will also be well applicable to other binary systems with polyhedron shape data. Our results on equilibrium points and associated periodic orbits provide general insights into the dynamical environment and orbital behaviors in proximity of small binary asteroids and enable the trajectory design and mission operations in future binary system explorations.

Correlative velocity fluctuations over a gravel river bed

USGS Publications Warehouse

Dinehart, Randal L.

1999-01-01

Velocity fluctuations in a steep, coarse‐bedded river were measured in flow depths ranging from 0.8 to 2.2 m, with mean velocities at middepth from 1.1 to 3.1 m s−1. Analyses of synchronous velocity records for two and three points in the vertical showed a broad range of high coherence for wave periods from 10 to 100 s, centering around 10–30 s. Streamwise correlations over distances of 9 and 14 m showed convection velocities near mean velocity for the same wave periods. The range of coherent wave periods was a small multiple of predicted “boil” periods. Correlative fluctuations in synchronous velocity records in the vertical direction suggested the blending of short pulses into longer wave periods. The highest spectral densities were measured beyond the range of coherent wave periods and were probably induced by migration of low‐relief bed forms.

A European mobile satellite system concept exploiting CDMA and OBP

NASA Technical Reports Server (NTRS)

Vernucci, A.; Craig, A. D.

1993-01-01

This paper describes a novel Land Mobile Satellite System (LMSS) concept applicable to networks allowing access to a large number of gateway stations ('Hubs'), utilizing low-cost Very Small Aperture Terminals (VSAT's). Efficient operation of the Forward-Link (FL) repeater can be achieved by adopting a synchronous Code Division Multiple Access (CDMA) technique, whereby inter-code interference (self-noise) is virtually eliminated by synchronizing orthogonal codes. However, with a transparent FL repeater, the requirements imposed by the highly decentralized ground segment can lead to significant efficiency losses. The adoption of a FL On-Board Processing (OBP) repeater is proposed as a means of largely recovering this efficiency impairment. The paper describes the network architecture, the system design and performance, the OBP functions and impact on implementation. The proposed concept, applicable to a future generation of the European LMSS, was developed in the context of a European Space Agency (ESA) study contract.

Multiple types of synchronization analysis for discontinuous Cohen-Grossberg neural networks with time-varying delays.

PubMed

Li, Jiarong; Jiang, Haijun; Hu, Cheng; Yu, Zhiyong

2018-03-01

This paper is devoted to the exponential synchronization, finite time synchronization, and fixed-time synchronization of Cohen-Grossberg neural networks (CGNNs) with discontinuous activations and time-varying delays. Discontinuous feedback controller and Novel adaptive feedback controller are designed to realize global exponential synchronization, finite time synchronization and fixed-time synchronization by adjusting the values of the parameters ω in the controller. Furthermore, the settling time of the fixed-time synchronization derived in this paper is less conservative and more accurate. Finally, some numerical examples are provided to show the effectiveness and flexibility of the results derived in this paper. Copyright © 2018 Elsevier Ltd. All rights reserved.

Breast Cancer with Synchronous Renal Cell Carcinoma: A Rare Presentation.

PubMed

Arjunan, Ravi; Kumar, Durgesh; Kumar, K V Veerendra; Premlatha, C S

2016-10-01

Primary cancer arising from multiple organs is a well known fact. Synchronous tumours have been most commonly associated with kidney cancer. Bladder, prostate, colorectal and lung cancer are the most common synchronous primaries with Renal Cell Carcinoma (RCC) identified till date. We found metachronous tumours of breast with RCC in literature search which included both metastatic tumours as well second primaries. Overall, 25 cases of metastatic breast tumours and eight cases of second primary in previously treated RCC have been reported in the literature. Here, we are reporting a case of synchronous presentation of carcinoma breast with RCC which is very rare because most of the multiple malignancies reported in the literature are metastatic tumours or metachronous breast malignancy with RCC.

Breast Cancer with Synchronous Renal Cell Carcinoma: A Rare Presentation

PubMed Central

Arjunan, Ravi; Kumar, K V Veerendra; Premlatha, C S

2016-01-01

Primary cancer arising from multiple organs is a well known fact. Synchronous tumours have been most commonly associated with kidney cancer. Bladder, prostate, colorectal and lung cancer are the most common synchronous primaries with Renal Cell Carcinoma (RCC) identified till date. We found metachronous tumours of breast with RCC in literature search which included both metastatic tumours as well second primaries. Overall, 25 cases of metastatic breast tumours and eight cases of second primary in previously treated RCC have been reported in the literature. Here, we are reporting a case of synchronous presentation of carcinoma breast with RCC which is very rare because most of the multiple malignancies reported in the literature are metastatic tumours or metachronous breast malignancy with RCC. PMID:27891445

Simulating synchronization in neuronal networks

NASA Astrophysics Data System (ADS)

Fink, Christian G.

2016-06-01

We discuss several techniques used in simulating neuronal networks by exploring how a network's connectivity structure affects its propensity for synchronous spiking. Network connectivity is generated using the Watts-Strogatz small-world algorithm, and two key measures of network structure are described. These measures quantify structural characteristics that influence collective neuronal spiking, which is simulated using the leaky integrate-and-fire model. Simulations show that adding a small number of random connections to an otherwise lattice-like connectivity structure leads to a dramatic increase in neuronal synchronization.

The synchronicity between the stock and the stock index via information in market

NASA Astrophysics Data System (ADS)

Gao, Hai-Ling; Li, Jiang-Cheng; Guo, Wei; Mei, Dong-Cheng

2018-02-01

The synchronicity between the stock and the stock-index in a market system is investigated. The results show that: (i) the synchronicity between the stock and the stock-index increases with the rising degree of market information capitalized into stock prices in certain range; (ii) the synchronicity decreases for large firm-specific information; (iii) the stock return synchronicity is small compared to the big noise trading, however the variance noise facilitates the synchronization within the tailored realms. These findings may be helpful in understanding the effect of market information on synchronicity, especially for the response of firm-specific information and noise trading to synchronicity.

A proportional integral estimator-based clock synchronization protocol for wireless sensor networks.

PubMed

Yang, Wenlun; Fu, Minyue

2017-11-01

Clock synchronization is an issue of vital importance in applications of WSNs. This paper proposes a proportional integral estimator-based protocol (EBP) to achieve clock synchronization for wireless sensor networks. As each local clock skew gradually drifts, synchronization accuracy will decline over time. Compared with existing consensus-based approaches, the proposed synchronization protocol improves synchronization accuracy under time-varying clock skews. Moreover, by restricting synchronization error of clock skew into a relative small quantity, it could reduce periodic re-synchronization frequencies. At last, a pseudo-synchronous implementation for skew compensation is introduced as synchronous protocol is unrealistic in practice. Numerical simulations are shown to illustrate the performance of the proposed protocol. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.

Small-world networks exhibit pronounced intermittent synchronization

NASA Astrophysics Data System (ADS)

Choudhary, Anshul; Mitra, Chiranjit; Kohar, Vivek; Sinha, Sudeshna; Kurths, Jürgen

2017-11-01

We report the phenomenon of temporally intermittently synchronized and desynchronized dynamics in Watts-Strogatz networks of chaotic Rössler oscillators. We consider topologies for which the master stability function (MSF) predicts stable synchronized behaviour, as the rewiring probability (p) is tuned from 0 to 1. MSF essentially utilizes the largest non-zero Lyapunov exponent transversal to the synchronization manifold in making stability considerations, thereby ignoring the other Lyapunov exponents. However, for an N-node networked dynamical system, we observe that the difference in its Lyapunov spectra (corresponding to the N - 1 directions transversal to the synchronization manifold) is crucial and serves as an indicator of the presence of intermittently synchronized behaviour. In addition to the linear stability-based (MSF) analysis, we further provide global stability estimate in terms of the fraction of state-space volume shared by the intermittently synchronized state, as p is varied from 0 to 1. This fraction becomes appreciably large in the small-world regime, which is surprising, since this limit has been otherwise considered optimal for synchronized dynamics. Finally, we characterize the nature of the observed intermittency and its dominance in state-space as network rewiring probability (p) is varied.

Synchronized and sustained release of multiple components in silymarin from erodible glyceryl monostearate matrix system.

PubMed

Lu, Cheng; Lu, Yi; Chen, Jian; Zhang, Wentong; Wu, Wei

2007-05-01

Development of sustained delivery systems for herbal medicines was very difficult because of their complexity in composition. The concept of synchronized release from sustained release systems, which is characterized by release of multiple components in their original ratio that defines a herbal medicine, served as the basis for keeping the original pharmacological activity. In this study, erodible matrix systems based on glyceryl monostearate and polyethylene glycol 6000 or poloxamer 188 were prepared to perform strict control on synchronized release of the five active components of silymarin, i.e. taxifolin, silychrystin, silydianin, isosilybin and silybin. The matrix system was prepared by a melt fusion method. Synchronized release was achieved with high similarity factor f(2) values between each two of the five components. Erosion profiles of the matrix were in good correlation with release profiles of the five components, showing erosion-controlled release mechanisms. Through tuning some of the formulation variables, the system can be adjusted for synchronized and sustained release of silymarin for oral administration. In vitro hemolysis study indicated that the synchronized release samples showed a much better stabilizing effect on erythrocyte membrane.

Coupled lasers: phase versus chaos synchronization.

PubMed

Reidler, I; Nixon, M; Aviad, Y; Guberman, S; Friesem, A A; Rosenbluh, M; Davidson, N; Kanter, I

2013-10-15

The synchronization of chaotic lasers and the optical phase synchronization of light originating in multiple coupled lasers have both been extensively studied. However, the interplay between these two phenomena, especially at the network level, is unexplored. Here, we experimentally compare these phenomena by controlling the heterogeneity of the coupling delay times of two lasers. While chaotic lasers exhibit deterioration in synchronization as the time delay heterogeneity increases, phase synchronization is found to be independent of heterogeneity. The experimental results are found to be in agreement with numerical simulations for semiconductor lasers.

Evolutionary Pathways for Asteroid Satellites

NASA Astrophysics Data System (ADS)

Jacobson, Seth Andrew

2015-08-01

The YORP-induced rotational fission hypothesis is a proposed mechanism for the creation of small asteroid binaries, which make up approximately 1/6-th of the near-Earth asteroid and small Main Belt asteroid populations. The YORP effect is a radiative torque that rotationally accelerates asteroids on timescales of thousands to millions of years. As asteroids rotationally accelerate, centrifugal accelerations on material within the body can match gravitational accelerations holding that material in place. When this occurs, that material goes into orbit. Once in orbit that material coalesces into a companion that undergoes continued dynamical evolution.Observations with radar, photometric and direct imaging techniques reveal a diverse array of small asteroid satellites. These systems can be sorted into a number of morphologies according to size, multiplicity of members, dynamical orbit and spin states, and member shapes. For instance, singly synchronous binaries have short separation distances between the two members, rapidly rotating oblate primary members, and tidally locked prolate secondary members. Other confirmed binary morphologies include doubly synchronous, tight asynchronous and wide asynchronous binaries. Related to these binary morphologies are unbound paired asteroid systems and bi-lobate contact binaries.A critical test for the YORP-induced rotational fission hypothesis is whether the binary asteroids produced evolve to the observed binary and related systems. In this talk I will review how this evolution is believed to occur according to gravitational dynamics, mutual body tides and the binary YORP effect.

Invariant Solar Sail Formations in Elliptical Sun-Synchronous Orbits

NASA Astrophysics Data System (ADS)

Parsay, Khashayar

Current and past missions that study the Earth's geomagnetic tail require multiple spacecraft to fly in formation about a highly eccentric Keplerian reference orbit that has its apogee inside a predefined science region of interest. Because the geomagnetic tail is directed along the Sun-Earth line and therefore rotates annually, inertially fixed Keplerian orbits are only aligned with the geomagnetic tail once per year. This limitation reduces the duration of the science phase to less than a few months annually. Solar sails are capable of creating non-Keplerian, Sun-synchronous orbits that rotate with the geomagnetic tail. A solar sail flying in a Sun-synchronous orbit will have a continuous presence in the geomagnetic tail throughout the entire year, which significantly improves the in situ observations of the magnetosphere. To achieve a Sun-synchronous orbit, a solar sail is required to maintain a Sun-pointing attitude, which leads to the artificial precession of the orbit apse line in a Sun-synchronous manner, leaving the orbit apogee inside the science region of interest throughout entire the year. To study the spatial and temporal variations of plasma in the highly dynamic environment of the magnetosphere, multiple spacecraft must fly in a formation. The objective for this dissertation is to investigate the feasibility of solar sail formation flying in the Earth-centered, Sun-synchronous orbit regime. The focus of this effort is to enable formation flying for a group of solar sails that maintain a nominally fixed Sun-pointing attitude during formation flight, solely for the purpose of precessing their orbit apse lines Sun-synchronously. A fixed-attitude solar sail formation is motivated by the difficulties in the simultaneous control of orbit and attitude in flying solar sails. First, the secular rates of the orbital elements resulting from the effects of solar radiation pressure (SRP) are determined using averaging theory for a Sun-pointing attitude sail. These averaged rates are used to analytically derive the necessary conditions for a drift-free solar sail formation in Sun-synchronous orbits, assuming a fixed Sun-pointing orientation for each sail in formation. Next, the problem of formation design is solved using nonlinear programming for optimal two-craft, three-craft, and four-craft solar sail formations, in terms of formation quality and stability. Finally, the problem of formation establishment is addressed using optimal control theory, assuming that the sails are capable of making small changes to their orientations with respect to the Sun. These studies demonstrate the feasibility of solar sail formation flying for exploring the geomagnetic tail and improve upon previous work, which only considered unnatural relative motions that require continuous use of active control to remain in formation.

Illumination-based synchronization of high-speed vision sensors.

PubMed

Hou, Lei; Kagami, Shingo; Hashimoto, Koichi

2010-01-01

To acquire images of dynamic scenes from multiple points of view simultaneously, the acquisition time of vision sensors should be synchronized. This paper describes an illumination-based synchronization method derived from the phase-locked loop (PLL) algorithm. Incident light to a vision sensor from an intensity-modulated illumination source serves as the reference signal for synchronization. Analog and digital computation within the vision sensor forms a PLL to regulate the output signal, which corresponds to the vision frame timing, to be synchronized with the reference. Simulated and experimental results show that a 1,000 Hz frame rate vision sensor was successfully synchronized with 32 μs jitters.

System and method for time synchronization in a wireless network

DOEpatents

Gonia, Patrick S.; Kolavennu, Soumitri N.; Mahasenan, Arun V.; Budampati, Ramakrishna S.

2010-03-30

A system includes multiple wireless nodes forming a cluster in a wireless network, where each wireless node is configured to communicate and exchange data wirelessly based on a clock. One of the wireless nodes is configured to operate as a cluster master. Each of the other wireless nodes is configured to (i) receive time synchronization information from a parent node, (ii) adjust its clock based on the received time synchronization information, and (iii) broadcast time synchronization information based on the time synchronization information received by that wireless node. The time synchronization information received by each of the other wireless nodes is based on time synchronization information provided by the cluster master so that the other wireless nodes substantially synchronize their clocks with the clock of the cluster master.

Perspective Taking and Synchronous Argumentation for Learning the Day/Night Cycle

ERIC Educational Resources Information Center

Schwarz, Baruch B.; Schur, Yaron; Pensso, Haim; Tayer, Naama

2011-01-01

Changing practices in schools is a very complex endeavor. This paper is about new practices we prompted to foster collaboration and critical reasoning in science classrooms: the presentation of pictures representing different perspectives, small group synchronous argumentation, and moderation of synchronous argumentation. A CSCL tool helped in…

Phase locked loop synchronization for direct detection optical PPM communication systems

NASA Technical Reports Server (NTRS)

Chen, C. C.; Gardner, C. S.

1985-01-01

Receiver timing synchronization of an optical pulse position modulation (PPM) communication system can be achieved using a phase locked loop (PLL) if the photodetector output is properly processed. The synchronization performance is shown to improve with increasing signal power and decreasing loop bandwidth. Bit error rate (BER) of the PLL synchronized PPM system is analyzed and compared to that for the perfectly synchronized system. It is shown that the increase in signal power needed to compensate for the imperfect synchronization is small (less than 0.1 dB) for loop bandwidths less than 0.1% of the slot frequency.

Android Protection Mechanism: A Signed Code Security Mechanism for Smartphone Applications

DTIC Science & Technology

2011-03-01

status registers, exceptions, endian support, unaligned access support, synchronization primitives , the Jazelle Extension, and saturated integer...supports comprehensive non-blocking shared-memory synchronization primitives that scale for multiple-processor system designs. This is an improvement... synchronization . Memory semaphores can be loaded and altered without interruption because the load and store operations are atomic. Processor

Multiple Two-Way Time Message Exchange (TTME) Time Synchronization for Bridge Monitoring Wireless Sensor Networks

PubMed Central

Shi, Fanrong; Tuo, Xianguo; Yang, Simon X.; Li, Huailiang; Shi, Rui

2017-01-01

Wireless sensor networks (WSNs) have been widely used to collect valuable information in Structural Health Monitoring (SHM) of bridges, using various sensors, such as temperature, vibration and strain sensors. Since multiple sensors are distributed on the bridge, accurate time synchronization is very important for multi-sensor data fusion and information processing. Based on shape of the bridge, a spanning tree is employed to build linear topology WSNs and achieve time synchronization in this paper. Two-way time message exchange (TTME) and maximum likelihood estimation (MLE) are employed for clock offset estimation. Multiple TTMEs are proposed to obtain a subset of TTME observations. The time out restriction and retry mechanism are employed to avoid the estimation errors that are caused by continuous clock offset and software latencies. The simulation results show that the proposed algorithm could avoid the estimation errors caused by clock drift and minimize the estimation error due to the large random variable delay jitter. The proposed algorithm is an accurate and low complexity time synchronization algorithm for bridge health monitoring. PMID:28471418

Multiple Two-Way Time Message Exchange (TTME) Time Synchronization for Bridge Monitoring Wireless Sensor Networks.

PubMed

Shi, Fanrong; Tuo, Xianguo; Yang, Simon X; Li, Huailiang; Shi, Rui

2017-05-04

Wireless sensor networks (WSNs) have been widely used to collect valuable information in Structural Health Monitoring (SHM) of bridges, using various sensors, such as temperature, vibration and strain sensors. Since multiple sensors are distributed on the bridge, accurate time synchronization is very important for multi-sensor data fusion and information processing. Based on shape of the bridge, a spanning tree is employed to build linear topology WSNs and achieve time synchronization in this paper. Two-way time message exchange (TTME) and maximum likelihood estimation (MLE) are employed for clock offset estimation. Multiple TTMEs are proposed to obtain a subset of TTME observations. The time out restriction and retry mechanism are employed to avoid the estimation errors that are caused by continuous clock offset and software latencies. The simulation results show that the proposed algorithm could avoid the estimation errors caused by clock drift and minimize the estimation error due to the large random variable delay jitter. The proposed algorithm is an accurate and low complexity time synchronization algorithm for bridge health monitoring.

Distributed Synchronization in Networks of Agent Systems With Nonlinearities and Random Switchings.

PubMed

Tang, Yang; Gao, Huijun; Zou, Wei; Kurths, Jürgen

2013-02-01

In this paper, the distributed synchronization problem of networks of agent systems with controllers and nonlinearities subject to Bernoulli switchings is investigated. Controllers and adaptive updating laws injected in each vertex of networks depend on the state information of its neighborhood. Three sets of Bernoulli stochastic variables are introduced to describe the occurrence probabilities of distributed adaptive controllers, updating laws and nonlinearities, respectively. By the Lyapunov functions method, we show that the distributed synchronization of networks composed of agent systems with multiple randomly occurring nonlinearities, multiple randomly occurring controllers, and multiple randomly occurring updating laws can be achieved in mean square under certain criteria. The conditions derived in this paper can be solved by semi-definite programming. Moreover, by mathematical analysis, we find that the coupling strength, the probabilities of the Bernoulli stochastic variables, and the form of nonlinearities have great impacts on the convergence speed and the terminal control strength. The synchronization criteria and the observed phenomena are demonstrated by several numerical simulation examples. In addition, the advantage of distributed adaptive controllers over conventional adaptive controllers is illustrated.

Synchronization of a self-sustained cold-atom oscillator

NASA Astrophysics Data System (ADS)

Heimonen, H.; Kwek, L. C.; Kaiser, R.; Labeyrie, G.

2018-04-01

Nonlinear oscillations and synchronization phenomena are ubiquitous in nature. We study the synchronization of self-oscillating magneto-optically trapped cold atoms to a weak external driving. The oscillations arise from a dynamical instability due the competition between the screened magneto-optical trapping force and the interatomic repulsion due to multiple scattering of light. A weak modulation of the trapping force allows the oscillations of the cloud to synchronize to the driving. The synchronization frequency range increases with the forcing amplitude. The corresponding Arnold tongue is experimentally measured and compared to theoretical predictions. Phase locking between the oscillator and drive is also observed.

Synchrony in human, mouse and bacterial cell cultures--a comparison

NASA Technical Reports Server (NTRS)

Helmstetter, Charles E.; Thornton, Maureen; Romero, Ana; Eward, K. Leigh

2003-01-01

Growth characteristics of synchronous human MOLT-4, human U-937 and mouse L1210 cultures produced with a new minimally-disturbing technology were compared to each other and to synchronous Escherichia coli B/r. Based on measurements of cell concentrations during synchronous growth, synchrony persisted in similar fashion for all cells. Cell size and DNA distributions in the mammalian cultures also progressed synchronously and reproducibly for multiple cell cycles. The results demonstrate that unambiguous multi-cycle synchrony, critical for verifying the absence of significant growth imbalances induced by the synchronization procedure, is feasible with these cell lines, and possibly others.

Geographic variation in density-dependent dynamics impacts the synchronizing effect of dispersal and regional stochasticity

Treesearch

Andrew M. Liebhold; Derek M. Johnson; Ottar N. Bj& #248rnstad

2006-01-01

Explanations for the ubiquitous presence of spatially synchronous population dynamics have assumed that density-dependent processes governing the dynamics of local populations are identical among disjunct populations, and low levels of dispersal or small amounts of regionalized stochasticity ("Moran effect") can act to synchronize populations. In this study...

Dynamics of rotationally fissioned asteroids: Source of observed small asteroid systems

NASA Astrophysics Data System (ADS)

Jacobson, Seth A.; Scheeres, Daniel J.

2011-07-01

We present a model of near-Earth asteroid (NEA) rotational fission and ensuing dynamics that describes the creation of synchronous binaries and all other observed NEA systems including: doubly synchronous binaries, high- e binaries, ternary systems, and contact binaries. Our model only presupposes the Yarkovsky-O'Keefe-Radzievskii-Paddack (YORP) effect, "rubble pile" asteroid geophysics, and gravitational interactions. The YORP effect torques a "rubble pile" asteroid until the asteroid reaches its fission spin limit and the components enter orbit about each other (Scheeres, D.J. [2007]. Icarus 189, 370-385). Non-spherical gravitational potentials couple the spin states to the orbit state and chaotically drive the system towards the observed asteroid classes along two evolutionary tracks primarily distinguished by mass ratio. Related to this is a new binary process termed secondary fission - the secondary asteroid of the binary system is rotationally accelerated via gravitational torques until it fissions, thus creating a chaotic ternary system. The initially chaotic binary can be stabilized to create a synchronous binary by components of the fissioned secondary asteroid impacting the primary asteroid, solar gravitational perturbations, and mutual body tides. These results emphasize the importance of the initial component size distribution and configuration within the parent asteroid. NEAs may go through multiple binary cycles and many YORP-induced rotational fissions during their approximately 10 Myr lifetime in the inner Solar System. Rotational fission and the ensuing dynamics are responsible for all NEA systems including the most commonly observed synchronous binaries.

Performance Analysis of a De-correlated Modified Code Tracking Loop for Synchronous DS-CDMA System under Multiuser Environment

NASA Astrophysics Data System (ADS)

Wu, Ya-Ting; Wong, Wai-Ki; Leung, Shu-Hung; Zhu, Yue-Sheng

This paper presents the performance analysis of a De-correlated Modified Code Tracking Loop (D-MCTL) for synchronous direct-sequence code-division multiple-access (DS-CDMA) systems under multiuser environment. Previous studies have shown that the imbalance of multiple access interference (MAI) in the time lead and time lag portions of the signal causes tracking bias or instability problem in the traditional correlating tracking loop like delay lock loop (DLL) or modified code tracking loop (MCTL). In this paper, we exploit the de-correlating technique to combat the MAI at the on-time code position of the MCTL. Unlike applying the same technique to DLL which requires an extensive search algorithm to compensate the noise imbalance which may introduce small tracking bias under low signal-to-noise ratio (SNR), the proposed D-MCTL has much lower computational complexity and exhibits zero tracking bias for the whole range of SNR, regardless of the number of interfering users. Furthermore, performance analysis and simulations based on Gold codes show that the proposed scheme has better mean square tracking error, mean-time-to-lose-lock and near-far resistance than the other tracking schemes, including traditional DLL (T-DLL), traditional MCTL (T-MCTL) and modified de-correlated DLL (MD-DLL).

Sparsely-synchronized brain rhythm in a small-world neural network

NASA Astrophysics Data System (ADS)

Kim, Sang-Yoon; Lim, Woochang

2013-07-01

Sparsely-synchronized cortical rhythms, associated with diverse cognitive functions, have been observed in electric recordings of brain activity. At the population level, cortical rhythms exhibit small-amplitude fast oscillations while at the cellular level, individual neurons show stochastic firings sparsely at a much lower rate than the population rate. We study the effect of network architecture on sparse synchronization in an inhibitory population of subthreshold Morris-Lecar neurons (which cannot fire spontaneously without noise). Previously, sparse synchronization was found to occur for cases of both global coupling ( i.e., regular all-to-all coupling) and random coupling. However, a real neural network is known to be non-regular and non-random. Here, we consider sparse Watts-Strogatz small-world networks which interpolate between a regular lattice and a random graph via rewiring. We start from a regular lattice with only short-range connections and then investigate the emergence of sparse synchronization by increasing the rewiring probability p for the short-range connections. For p = 0, the average synaptic path length between pairs of neurons becomes long; hence, only an unsynchronized population state exists because the global efficiency of information transfer is low. However, as p is increased, long-range connections begin to appear, and global effective communication between distant neurons may be available via shorter synaptic paths. Consequently, as p passes a threshold p th (}~ 0.044), sparsely-synchronized population rhythms emerge. However, with increasing p, longer axon wirings become expensive because of their material and energy costs. At an optimal value p* DE (}~ 0.24) of the rewiring probability, the ratio of the synchrony degree to the wiring cost is found to become maximal. In this way, an optimal sparse synchronization is found to occur at a minimal wiring cost in an economic small-world network through trade-off between synchrony and wiring cost.

Mutual synchronization of weakly coupled gyrotrons

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rozental, R. M.; Glyavin, M. Yu.; Sergeev, A. S.

2015-09-15

The processes of synchronization of two weakly coupled gyrotrons are studied within the framework of non-stationary equations with non-fixed longitudinal field structure. With the allowance for a small difference of the free oscillation frequencies of the gyrotrons, we found a certain range of parameters where mutual synchronization is possible while a high electronic efficiency is remained. It is also shown that synchronization regimes can be realized even under random fluctuations of the parameters of the electron beams.

Approximation methods for the stability analysis of complete synchronization on duplex networks

NASA Astrophysics Data System (ADS)

Han, Wenchen; Yang, Junzhong

2018-01-01

Recently, the synchronization on multi-layer networks has drawn a lot of attention. In this work, we study the stability of the complete synchronization on duplex networks. We investigate effects of coupling function on the complete synchronization on duplex networks. We propose two approximation methods to deal with the stability of the complete synchronization on duplex networks. In the first method, we introduce a modified master stability function and, in the second method, we only take into consideration the contributions of a few most unstable transverse modes to the stability of the complete synchronization. We find that both methods work well for predicting the stability of the complete synchronization for small networks. For large networks, the second method still works pretty well.

Precise Time Synchronisation and Ranging in Nano-Satellite Swarms

NASA Astrophysics Data System (ADS)

Laabs, Martin; Plettemeier, Dirk

2015-04-01

Precise time synchronization and ranging is very important for a variety of scientific experiments with more than two nano-satellites: For synthetic aperture radar (SAR) applications, for example, the radar signal phase (which corresponds to a synchronized time) as well as the location must be known on each satellite forming synthetic antenna. Also multi-static radar systems, MIMO radar systems or radio tomography applications will take advantage from highly accurate synchronization and position determination. We propose a method for synchronizing the time as well as measuring the distance between nano-satellites very precisely by utilizing mm-wave radio links. This approach can also be used for time synchronization of more than two satellites and accordingly determinating the precise relative location of nano-satellites in space. The time synchronization signal is modulated onto a mm-wave carrier. In the simplest form it is a harmonic sinusoidal signal with a frequency in the MHz range. The distance is measured with a frequency sweep or short pulse modulated onto a different carrier frequency. The sweep or pulse transmission start is synchronized to the received time synchronization. The time synchronization transmitter receives the pulse/sweep signal and can calculate the (double) time of flight for both signals. This measurement can be easily converted to the distance. The use of a mm-wave carrier leads to small antennas and the free space loss linked to the high frequency reduces non line of sight echoes. It also allows a high sweep/pulse bandwidth enabling superior ranging accuracy. Additionally, there is also less electromagnetic interference probability since telemetry and scientific applications typically do not use mm-wavefrequencies. Since the system is working full-duplex the time synchronization can be performed continuously and coherently. Up to now the required semiconductor processes did not achieve enough gain/bandwidth to realize this concept at frequencies above 60GHz in a small, cost effective and low power integrated circuit. But with the state of the art (commercial available) SiGe and p-HEMPT GaAs semiconductor processes it becomes possible to implement this concept even at 300GHz in a small MMIC or hybrid circuit.

Damping torque analysis of VSC-based system utilizing power synchronization control

NASA Astrophysics Data System (ADS)

Fu, Q.; Du, W. J.; Zheng, K. Y.; Wang, H. F.

2017-05-01

Power synchronization control is a new control strategy of VSC-HVDC for connecting a weak power system. Different from the vector control method, this control method utilizes the internal synchronization mechanism in ac systems, in principle, similar to the operation of a synchronous machine. So that the parameters of controllers in power synchronization control will change the electromechanical oscillation modes and make an impact on the transient stability of power system. This paper present a mathematical model for small-signal stability analysis of VSC station used power synchronization control and analyse the impact of the dynamic interactions by calculating the contribution of the damping torque from the power synchronization control, besides, the parameters of controllers which correspond to damping torque and synchronous torque in the power synchronization control is defined respectively. At the end of the paper, an example power system is presented to demonstrate and validate the theoretical analysis and associated conclusions are made.

Analysis of synchronous and induction generators used at hydroelectric power plant

NASA Astrophysics Data System (ADS)

Diniş, C. M.; Popa, G. N.; lagăr, A.

2017-01-01

In this paper is presented an analysis of the operating electric generators (synchronous and induction) within a small capacity hydroelectric power plant. Such is treated the problem of monitoring and control hydropower plant using SCADA systems. Have been carried an experimental measurements in small hydropower plant for different levels of water in the lake and various settings of the operating parameters.

Generation-based memory synchronization in a multiprocessor system with weakly consistent memory accesses

DOEpatents

Ohmacht, Martin

2017-08-15

In a multiprocessor system, a central memory synchronization module coordinates memory synchronization requests responsive to memory access requests in flight, a generation counter, and a reclaim pointer. The central module communicates via point-to-point communication. The module includes a global OR reduce tree for each memory access requesting device, for detecting memory access requests in flight. An interface unit is implemented associated with each processor requesting synchronization. The interface unit includes multiple generation completion detectors. The generation count and reclaim pointer do not pass one another.

Generation-based memory synchronization in a multiprocessor system with weakly consistent memory accesses

DOEpatents

Ohmacht, Martin

2014-09-09

In a multiprocessor system, a central memory synchronization module coordinates memory synchronization requests responsive to memory access requests in flight, a generation counter, and a reclaim pointer. The central module communicates via point-to-point communication. The module includes a global OR reduce tree for each memory access requesting device, for detecting memory access requests in flight. An interface unit is implemented associated with each processor requesting synchronization. The interface unit includes multiple generation completion detectors. The generation count and reclaim pointer do not pass one another.

Orbit-attitude coupled motion around small bodies: Sun-synchronous orbits with Sun-tracking attitude motion

NASA Astrophysics Data System (ADS)

Kikuchi, Shota; Howell, Kathleen C.; Tsuda, Yuichi; Kawaguchi, Jun'ichiro

2017-11-01

The motion of a spacecraft in proximity to a small body is significantly perturbed due to its irregular gravity field and solar radiation pressure. In such a strongly perturbed environment, the coupling effect of the orbital and attitude motions exerts a large influence that cannot be neglected. However, natural orbit-attitude coupled dynamics around small bodies that are stationary in both orbital and attitude motions have yet to be observed. The present study therefore investigates natural coupled motion that involves both a Sun-synchronous orbit and Sun-tracking attitude motion. This orbit-attitude coupled motion enables a spacecraft to maintain its orbital geometry and attitude state with respect to the Sun without requiring active control. Therefore, the proposed method can reduce the use of an orbit and attitude control system. This paper first presents analytical conditions to achieve Sun-synchronous orbits and Sun-tracking attitude motion. These analytical solutions are then numerically propagated based on non-linear coupled orbit-attitude equations of motion. Consequently, the possibility of implementing Sun-synchronous orbits with Sun-tracking attitude motion is demonstrated.

Using Abstraction in Explicity Parallel Programs.

DTIC Science & Technology

1991-07-01

However, we only rely on sequential consistency of memory operations. includ- ing reads. writes and any synchronization primitives provided by the...explicit synchronization primitives . This demonstrates the practical power of sequentially consistent memory, as opposed to weaker models of memory that...a small set of synchronization primitives , all pro- cedures have non-waiting specifications. This is in contrast to richer process-oriented

Supporting Academic Integrity in a Fully-Online Degree Completion Program through the Use of Synchronous Video Conferences

ERIC Educational Resources Information Center

Wagner, Erica; Enders, Jeanne; Pirie, Melissa Shaquid; Thomas, Domanic

2016-01-01

Since 2012, we have used synchronous, web-based video conferences in our fully-online degree completion program. Students are required to participate in four live video conferences with their professor and a small group of peers in all upper division online courses as a minimum requirement for passing the class. While these synchronous video…

Synchronous microencapsulation of multiple components in silymarin into PLGA nanoparticles by an emulsification/solvent evaporation method.

PubMed

Xie, Yunchang; Yi, Yueneng; Hu, Xiongwei; Shangguan, Mingzhu; Wang, Lijuan; Lu, Yi; Qi, Jianping; Wu, Wei

2016-09-01

The development of polymeric carriers loaded with extracts suffers from the drawback not to be able to incorporate simultaneously various pharmacological compounds into the formulation. The aim of this study was therefore to achieve synchronous microencapsulation of multiple components of silymarin into poly (lactic-co-glycolic acid) nanoparticle, the most commonly used polymeric carrier with biodegradability and safety. The main strategy taken was to improve the overall entrapment efficiency and to reduce the escaping ratio of the components of different physicochemical properties. The optimized nanoparticles were spherical in morphology with a mean particle size of 150 ± 5 nm. Under common preparative conditions, silybin and isosilybin were entrapped in high efficiency, whereas taxifolin, silychristin and silydianin, especially taxifolin, showed less entrapment because they were more hydrophilic. By changing the pH of the outer aqueous phase and saturating it with silymarin, the entrapment efficiency of taxifolin, silychristin and silydianin could be significantly improved to over 90%, the level similar to silybin and isosilybin, thereby achieving synchronous encapsulation. It could be concluded that synchronous encapsulation of multiple components of silymarin was achieved by optimizing the preparative variables.

Wireless Synchronization of a Multi-Pinhole Small Animal SPECT Collimation Device With a Clinical Scanner

NASA Astrophysics Data System (ADS)

DiFilippo, Frank P.; Patel, Sagar

2009-06-01

A multi-pinhole collimation device for small animal single photon emission computed tomography (SPECT) uses the gamma camera detectors of a standard clinical SPECT scanner. The collimator and animal bed move independently of the detectors, and therefore their motions must be synchronized. One approach is manual triggering of the SPECT acquisition simultaneously with a programmed motion sequence for the device. However, some data blurring and loss of image quality result, and true electronic synchronization is preferred. An off-the-shelf digital gyroscope with integrated Bluetooth interface provides a wireless solution to device synchronization. The sensor attaches to the SPECT gantry and reports its rotational speed to a notebook computer controlling the device. Software processes the rotation data in real-time, averaging the signal and issuing triggers while compensating for baseline drift. Motion commands are sent to the collimation device with minimal delay, within approximately 0.5 second of the start of SPECT gantry rotation. Test scans of a point source demonstrate an increase in true counts and a reduction in background counts compared to manual synchronization. The wireless rotation sensor provides robust synchronization of the collimation device with the clinical SPECT scanner and enhances image quality.

Electrohydraulic Synchronizing Servo Control of a Robotic Arm

NASA Astrophysics Data System (ADS)

Li, S.; Ruan, J.; Pei, X.; Yu, Z. Q.; Zhu, F. M.

2006-10-01

The large robotic arm is usually driven by the electrodraulic synchronizing control system. The electrodraulic synchronizing system is designed with the digital valve to eliminate the effect of the nonlinearities, such as hysteresis, saturation, definite resolution. The working principle of the electrodraulic synchronizing control system is introduced and the mathematical model is established through construction of flow rate equation, continuity equation, force equilibrium equation, etc. To obtain the high accuracy, the PID control is introduced in the system. Simulation analysis shows that the dynamic performance of the synchronizing system is good, and its steady state error is very small. To validate the results, the experimental set-up of the synchronizing system is built. The experiment makes it clear that the control system has high accuracy. The synchronizing system can be applied widely in practice.

Anti-synchronization control of BAM memristive neural networks with multiple proportional delays and stochastic perturbations

NASA Astrophysics Data System (ADS)

Wang, Weiping; Yuan, Manman; Luo, Xiong; Liu, Linlin; Zhang, Yao

2018-01-01

Proportional delay is a class of unbounded time-varying delay. A class of bidirectional associative memory (BAM) memristive neural networks with multiple proportional delays is concerned in this paper. First, we propose the model of BAM memristive neural networks with multiple proportional delays and stochastic perturbations. Furthermore, by choosing suitable nonlinear variable transformations, the BAM memristive neural networks with multiple proportional delays can be transformed into the BAM memristive neural networks with constant delays. Based on the drive-response system concept, differential inclusions theory and Lyapunov stability theory, some anti-synchronization criteria are obtained. Finally, the effectiveness of proposed criteria are demonstrated through numerical examples.

How to induce multiple delays in coupled chaotic oscillators?

NASA Astrophysics Data System (ADS)

Bhowmick, Sourav K.; Ghosh, Dibakar; Roy, Prodyot K.; Kurths, Jürgen; Dana, Syamal K.

2013-12-01

Lag synchronization is a basic phenomenon in mismatched coupled systems, delay coupled systems, and time-delayed systems. It is characterized by a lag configuration that identifies a unique time shift between all pairs of similar state variables of the coupled systems. In this report, an attempt is made how to induce multiple lag configurations in coupled systems when different pairs of state variables attain different time shift. A design of coupling is presented to realize this multiple lag synchronization. Numerical illustration is given using examples of the Rössler system and the slow-fast Hindmarsh-Rose neuron model. The multiple lag scenario is physically realized in an electronic circuit of two Sprott systems.

Broadband Time Division Multiple Access (TDMA) Solution (Tech Insertion - C4 Enhancement for the U.S. Army in Transformation)

DTIC Science & Technology

2005-06-01

synchronization , timing and frequency to all of the traffic terminals through the reference burst. The MRT also periodically synchronizes all of the traffic...1 2005 Command and Control Research and Technology Symposium The Future of C2 Broadband Time Division Multiple Access (TDMA) Solution...UK Army) Dale White Barry Kruse Shawn White LTC Edward Eidson Thomas Mims COL Charles Dunn III Charlie Pangle Battle Command Battle

Clinicopathological characteristics of synchronous and metachronous gastric neoplasms after endoscopic submucosal dissection

PubMed Central

Jang, Mi Young; Oh, Wang Guk; Ko, Sung Jun; Han, Shang Hoon; Baek, Hoon Ki; Lee, Young Jae; Kim, Ji Woong; Jung, Gum Mo; Cho, Yong Keun

2013-01-01

Background/Aims Endoscopic submucosal dissection (ESD) has become accepted as a minimally invasive treatment for gastric neoplasms. However, the development of synchronous or metachronous gastric lesions after endoscopic resection has become a major problem. We investigated the characteristics of multiple gastric neoplasms in patients with early gastric cancer (EGC) or gastric adenoma after ESD. Methods In total, 512 patients with EGC or gastric adenoma who had undergone ESD between January 2008 and December 2011 participated in this study. The incidence of and factors associated with synchronous and metachronous gastric tumors were investigated in this retrospective study. Results In total, 66 patients (12.9%) had synchronous lesions, and 13 patients (2.5%) had metachronous lesions. Older (> 65 years) subjects had an increased risk of multiple gastric neoplasms (p = 0.012). About two-thirds of the multiple lesions were similar in macroscopic and histological type to the primary lesions. The median interval from the initial lesions to the diagnosis of metachronous lesions was 31 months. The annual incidence rate of metachronous lesions was approximately 3%. Conclusions We recommend careful follow-up in patients of advanced age (> 65 years) after initial ESD because multiple lesions could be detected in the remnant stomach. Annual surveillance might aid in the detection of metachronous lesions. Large-scale, multicenter, and longer prospective studies of appropriate surveillance programs are needed. PMID:24307844

Postoperative Management of Multiple Primary Cancers Associated with Non-small Cell Lung Cancer.

PubMed

Shoji, Fumihiro; Yamazaki, Koji; Miura, Naoko; Katsura, Masakazu; Oku, Yuka; Takeo, Sadanori; Maehara, Yoshihiko

2018-06-01

Modern treatment for primary cancers has improved survival. Therefore, increased numbers of patients with multiple primary cancers (MPC) associated with lung cancer may be expected. The aim of the present study was to report MPC associated with lung cancer and discuss patients' characteristics and postoperative management. Overall, 973 consecutive patients who underwent surgery for non-small cell lung cancer (NSCLC) were retrospectively studied. NSCLC with MPC was observed in 148 patients (15.2%). MPC comprised 24 synchronous (2.5%) and 124 metachronous (12.7%) diseases. Of the 124 metachronous patients, NSCLC was detected before cancers were detected in other organs (lung cancer first (LCF)) in 25 (20.2%) patients and subsequently in other organs after treatment (other organs, primary cancer-first (OCF)) in 99 (79.8%) patients. MPC was significantly associated with advanced age (p<0.0001) and chronic obstructive pulmonary disease (COPD) (p=0.0040). The leading sites of MPC in patients with synchronous tumors and those with OCF were the digestive organs. In contrast, the leading site of MPC in patients with LCF was the lung. In the latter, at least two primary lung cancers were detected within 5 years as well as 5 years after surgery for the treatment of the first detected lung cancer, while primary cancers of other organs were detected within 5 years. Advanced age and COPD may represent a high-risk of MPCs. Therefore, we recommend careful follow-up to detect MPC in the lung as well as the digestive organs beyond 5 years after treatment of the first cancer. Copyright© 2018, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Assessing the Multiple Dimensions of Engagement to Characterize Learning: A Neurophysiological Perspective

PubMed Central

Charland, Patrick; Léger, Pierre-Majorique; Sénécal, Sylvain; Courtemanche, François; Mercier, Julien; Skelling, Yannick; Labonté-Lemoyne, Elise

2015-01-01

In a recent theoretical synthesis on the concept of engagement, Fredricks, Blumenfeld and Paris1 defined engagement by its multiple dimensions: behavioral, emotional and cognitive. They observed that individual types of engagement had not been studied in conjunction, and little information was available about interactions or synergy between the dimensions; consequently, more studies would contribute to creating finely tuned teaching interventions. Benefiting from the recent technological advances in neurosciences, this paper presents a recently developed methodology to gather and synchronize data on multidimensional engagement during learning tasks. The technique involves the collection of (a) electroencephalography, (b) electrodermal, (c) eye-tracking, and (d) facial emotion recognition data on four different computers. This led to synchronization issues for data collected from multiple sources. Post synchronization in specialized integration software gives researchers a better understanding of the dynamics between the multiple dimensions of engagement. For curriculum developers, these data could provide informed guidelines for achieving better instruction/learning efficiency. This technique also opens up possibilities in the field of brain-computer interactions, where adaptive learning or assessment environments could be developed. PMID:26167712

Neuronal synchrony: Peculiarity and generality

PubMed Central

Nowotny, Thomas; Huerta, Ramon; Rabinovich, Mikhail I.

2008-01-01

Synchronization in neuronal systems is a new and intriguing application of dynamical systems theory. Why are neuronal systems different as a subject for synchronization? (1) Neurons in themselves are multidimensional nonlinear systems that are able to exhibit a wide variety of different activity patterns. Their “dynamical repertoire” includes regular or chaotic spiking, regular or chaotic bursting, multistability, and complex transient regimes. (2) Usually, neuronal oscillations are the result of the cooperative activity of many synaptically connected neurons (a neuronal circuit). Thus, it is necessary to consider synchronization between different neuronal circuits as well. (3) The synapses that implement the coupling between neurons are also dynamical elements and their intrinsic dynamics influences the process of synchronization or entrainment significantly. In this review we will focus on four new problems: (i) the synchronization in minimal neuronal networks with plastic synapses (synchronization with activity dependent coupling), (ii) synchronization of bursts that are generated by a group of nonsymmetrically coupled inhibitory neurons (heteroclinic synchronization), (iii) the coordination of activities of two coupled neuronal networks (partial synchronization of small composite structures), and (iv) coarse grained synchronization in larger systems (synchronization on a mesoscopic scale). PMID:19045493

Fast sparsely synchronized brain rhythms in a scale-free neural network

NASA Astrophysics Data System (ADS)

Kim, Sang-Yoon; Lim, Woochang

2015-08-01

We consider a directed version of the Barabási-Albert scale-free network model with symmetric preferential attachment with the same in- and out-degrees and study the emergence of sparsely synchronized rhythms for a fixed attachment degree in an inhibitory population of fast-spiking Izhikevich interneurons. Fast sparsely synchronized rhythms with stochastic and intermittent neuronal discharges are found to appear for large values of J (synaptic inhibition strength) and D (noise intensity). For an intensive study we fix J at a sufficiently large value and investigate the population states by increasing D . For small D , full synchronization with the same population-rhythm frequency fp and mean firing rate (MFR) fi of individual neurons occurs, while for large D partial synchronization with fp> ( : ensemble-averaged MFR) appears due to intermittent discharge of individual neurons; in particular, the case of fp>4 is referred to as sparse synchronization. For the case of partial and sparse synchronization, MFRs of individual neurons vary depending on their degrees. As D passes a critical value D* (which is determined by employing an order parameter), a transition to unsynchronization occurs due to the destructive role of noise to spoil the pacing between sparse spikes. For D

Increase in Synchronization of Autonomic Rhythms between Individuals When Listening to Music

PubMed Central

Bernardi, Nicolò F.; Codrons, Erwan; di Leo, Rita; Vandoni, Matteo; Cavallaro, Filippo; Vita, Giuseppe; Bernardi, Luciano

2017-01-01

In light of theories postulating a role for music in forming emotional and social bonds, here we investigated whether endogenous rhythms synchronize between multiple individuals when listening to music. Cardiovascular and respiratory recordings were taken from multiple individuals (musically trained or music-naïve) simultaneously, at rest and during a live concert comprising music excerpts with varying degrees of complexity of the acoustic envelope. Inter-individual synchronization of cardiorespiratory rhythms showed a subtle but reliable increase during passively listening to music compared to baseline. The low-level auditory features of the music were largely responsible for creating or disrupting such synchronism, explaining ~80% of its variance, over and beyond subjective musical preferences and previous musical training. Listening to simple rhythms and melodies, which largely dominate the choice of music during rituals and mass events, brings individuals together in terms of their physiological rhythms, which could explain why music is widely used to favor social bonds. PMID:29089898

TADPOLE satellite. [low cost synchronous orbit satellite to evaluate small mercury bombardment ion thruster applications

NASA Technical Reports Server (NTRS)

1974-01-01

A low cost synchronous orbit satellite to evaluate small mercury bombardment ion thruster applications is described. The ion thrusters provide the satellite with precise north-south and east-west stationkeeping capabilities. In addition, the thrusters are used to unload the reaction wheels used for attitude control and for other purposes described in the report. The proposed satellite is named TADPOLE. (Technology Application Demonstration Program of Low Energy).

Effect of intermodular connection on fast sparse synchronization in clustered small-world neural networks

NASA Astrophysics Data System (ADS)

Kim, Sang-Yoon; Lim, Woochang

2015-11-01

We consider a clustered network with small-world subnetworks of inhibitory fast spiking interneurons and investigate the effect of intermodular connection on the emergence of fast sparsely synchronized rhythms by varying both the intermodular coupling strength Jinter and the average number of intermodular links per interneuron Msyn(inter ). In contrast to the case of nonclustered networks, two kinds of sparsely synchronized states such as modular and global synchronization are found. For the case of modular sparse synchronization, the population behavior reveals the modular structure, because the intramodular dynamics of subnetworks make some mismatching. On the other hand, in the case of global sparse synchronization, the population behavior is globally identical, independently of the cluster structure, because the intramodular dynamics of subnetworks make perfect matching. We introduce a realistic cross-correlation modularity measure, representing the matching degree between the instantaneous subpopulation spike rates of the subnetworks, and examine whether the sparse synchronization is global or modular. Depending on its magnitude, the intermodular coupling strength Jinter seems to play "dual" roles for the pacing between spikes in each subnetwork. For large Jinter, due to strong inhibition it plays a destructive role to "spoil" the pacing between spikes, while for small Jinter it plays a constructive role to "favor" the pacing between spikes. Through competition between the constructive and the destructive roles of Jinter, there exists an intermediate optimal Jinter at which the pacing degree between spikes becomes maximal. In contrast, the average number of intermodular links per interneuron Msyn(inter ) seems to play a role just to favor the pacing between spikes. With increasing Msyn(inter ), the pacing degree between spikes increases monotonically thanks to the increase in the degree of effectiveness of global communication between spikes. Furthermore, we employ the realistic sub- and whole-population order parameters, based on the instantaneous sub- and whole-population spike rates, to determine the threshold values for the synchronization-unsynchronization transition in the sub- and whole populations, and the degrees of global and modular sparse synchronization are also measured in terms of the realistic sub- and whole-population statistical-mechanical spiking measures defined by considering both the occupation and the pacing degrees of spikes. It is expected that our results could have implications for the role of the brain plasticity in some functional behaviors associated with population synchronization.

Experimental synchronization of chaos in a large ring of mutually coupled single-transistor oscillators: phase, amplitude, and clustering effects.

PubMed

Minati, Ludovico

2014-12-01

In this paper, experimental evidence of multiple synchronization phenomena in a large (n = 30) ring of chaotic oscillators is presented. Each node consists of an elementary circuit, generating spikes of irregular amplitude and comprising one bipolar junction transistor, one capacitor, two inductors, and one biasing resistor. The nodes are mutually coupled to their neighbours via additional variable resistors. As coupling resistance is decreased, phase synchronization followed by complete synchronization is observed, and onset of synchronization is associated with partial synchronization, i.e., emergence of communities (clusters). While component tolerances affect community structure, the general synchronization properties are maintained across three prototypes and in numerical simulations. The clusters are destroyed by adding long distance connections with distant notes, but are otherwise relatively stable with respect to structural connectivity changes. The study provides evidence that several fundamental synchronization phenomena can be reliably observed in a network of elementary single-transistor oscillators, demonstrating their generative potential and opening way to potential applications of this undemanding setup in experimental modelling of the relationship between network structure, synchronization, and dynamical properties.

Synchronous Hepatoblastoma, Neuroblastoma, and Cutaneous Capillary Hemangiomas: A Case Report.

PubMed

Ozawa, Michael G; Cooney, Tabitha; Rangaswami, Arun; Hazard, Florette K

2016-01-01

Multiple synchronous tumors presenting in infancy raise concern for inherited or sporadic cancer predisposition syndromes, which include Beckwith-Wiedemann syndrome, familial adenomatous polyposis syndrome, and Li-Fraumeni syndrome. We report a case of a 7-month-old previously healthy male born following an in vitro fertilization-assisted twin pregnancy who presented with new-onset refractory shock, severe acidosis, and rapid decline over several hours. An autopsy revealed a ruptured liver involved by hepatoblastoma, an adrenal gland involved by neuroblastoma, and multiple cutaneous capillary hemangiomas. Standard genetic testing demonstrated that both twins were Gaucher disease (GD) carriers without evidence of other known cancer predisposition syndromes. This report describes a unique association of multiple synchronous tumors, which underscores the utility and importance of the pediatric autopsy. Moreover, given that the reported child was a GD carrier, the possibility the tumors were the result of a GD-mediated cancer-associated phenotype or an unrecognized sporadic clinical syndrome remains an unanswered, but intriguing, question worthy of further investigation.

Practical multipeptide synthesis: dedicated software for the definition of multiple, overlapping peptides covering polypeptide sequences.

PubMed

Heegaard, P M; Holm, A; Hagerup, M

1993-01-01

A personal computer program for the conversion of linear amino acid sequences to multiple, small, overlapping peptide sequences has been developed. Peptide lengths and "jumps" (the distance between two consecutive overlapping peptides) are defined by the user. To facilitate the use of the program for parallel solid-phase chemical peptide syntheses for the synchronous production of multiple peptides, amino acids at each acylation step are laid out by the program in a convenient standard multi-well setup. Also, the total number of equivalents, as well as the derived amount in milligrams (depend-ending on user-defined equivalent weights and molar surplus), of each amino acid are given. The program facilitates the implementation of multipeptide synthesis, e.g., for the elucidation of polypeptide structure-function relationships, and greatly reduces the risk of introducing mistakes at the planning step. It is written in Pascal and runs on any DOS-based personal computer. No special graphic display is needed.

What Scientific Applications can Benefit from Hardware Transactional Memory?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schindewolf, M; Bihari, B; Gyllenhaal, J

2012-06-04

Achieving efficient and correct synchronization of multiple threads is a difficult and error-prone task at small scale and, as we march towards extreme scale computing, will be even more challenging when the resulting application is supposed to utilize millions of cores efficiently. Transactional Memory (TM) is a promising technique to ease the burden on the programmer, but only recently has become available on commercial hardware in the new Blue Gene/Q system and hence the real benefit for realistic applications has not been studied, yet. This paper presents the first performance results of TM embedded into OpenMP on a prototype systemmore » of BG/Q and characterizes code properties that will likely lead to benefits when augmented with TM primitives. We first, study the influence of thread count, environment variables and memory layout on TM performance and identify code properties that will yield performance gains with TM. Second, we evaluate the combination of OpenMP with multiple synchronization primitives on top of MPI to determine suitable task to thread ratios per node. Finally, we condense our findings into a set of best practices. These are applied to a Monte Carlo Benchmark and a Smoothed Particle Hydrodynamics method. In both cases an optimized TM version, executed with 64 threads on one node, outperforms a simple TM implementation. MCB with optimized TM yields a speedup of 27.45 over baseline.« less

Synchronized parameter optimization of the double freeform lenses illumination system used for the CF-LCoS pico-projectors

NASA Astrophysics Data System (ADS)

Chen, Enguo; Liu, Peng; Yu, Feihong

2012-10-01

A novel synchronized optimization method of multiple freeform surfaces is proposed and applied to double lenses illumination system design of CF-LCoS pico-projectors. Based on Snell's law and the energy conservation law, a series of first-order partial differential equations are derived for the multiple freeform surfaces of the initial system. By assigning the light deflection angle to each freeform surface, multiple surfaces can be obtained simultaneously by solving the corresponding equations, meanwhile the restricted angle on CF-LCoS is guaranteed. In order to improve the spatial uniformity, the multi-surfaces are synchronously optimized by using simplex algorithm for an extended LED source. Design example shows that the double lenses based illumination system, which employs a single 2 mm×2 mm LED chip and a CF-LCoS panel with a diagonal of 0.59 inches satisfies the needs of pico-projector. Moreover, analytical result indicates that the design method represents substantial improvement and practical significance over traditional CF-LCoS projection system, which could offer outstanding performance with both portability and low cost. The synchronized optimization design method could not only realize collimating and uniform illumination, but also could be introduced to other specific light conditions.

Frame Synchronization Without Attached Sync Markers

NASA Technical Reports Server (NTRS)

Hamkins, Jon

2011-01-01

We describe a method to synchronize codeword frames without making use of attached synchronization markers (ASMs). Instead, the synchronizer identifies the code structure present in the received symbols, by operating the decoder for a handful of iterations at each possible symbol offset and forming an appropriate metric. This method is computationally more complex and doesn't perform as well as frame synchronizers that utilize an ASM; nevertheless, the new synchronizer acquires frame synchronization in about two seconds when using a 600 kbps software decoder, and would take about 15 milliseconds on prototype hardware. It also eliminates the need for the ASMs, which is an attractive feature for short uplink codes whose coding gain would be diminished by the overheard of ASM bits. The lack of ASMs also would simplify clock distribution for the AR4JA low-density parity-check (LDPC) codes and adds a small amount to the coding gain as well (up to 0.2 dB).

Noise effects on robust synchronization of a small pacemaker neuronal ensemble via nonlinear controller: electronic circuit design.

PubMed

Megam Ngouonkadi, Elie Bertrand; Fotsin, Hilaire Bertrand; Kabong Nono, Martial; Louodop Fotso, Patrick Herve

2016-10-01

In this paper, we report on the synchronization of a pacemaker neuronal ensemble constituted of an AB neuron electrically coupled to two PD neurons. By the virtue of this electrical coupling, they can fire synchronous bursts of action potential. An external master neuron is used to induce to the whole system the desired dynamics, via a nonlinear controller. Such controller is obtained by a combination of sliding mode and feedback control. The proposed controller is able to offset uncertainties in the synchronized systems. We show how noise affects the synchronization of the pacemaker neuronal ensemble, and briefly discuss its potential benefits in our synchronization scheme. An extended Hindmarsh-Rose neuronal model is used to represent a single cell dynamic of the network. Numerical simulations and Pspice implementation of the synchronization scheme are presented. We found that, the proposed controller reduces the stochastic resonance of the network when its gain increases.

Angle restriction enhances synchronization of self-propelled objects.

PubMed

Gao, Jianxi; Havlin, Shlomo; Xu, Xiaoming; Stanley, H Eugene

2011-10-01

Understanding the synchronization process of self-propelled objects is of great interest in science and technology. We propose a synchronization model for a self-propelled objects system in which we restrict the maximal angle change of each object to θ(R). At each time step, each object moves and changes its direction according to the average direction of all of its neighbors (including itself). If the angle change is greater than a cutoff angle θ(R), the change is replaced by θ(R). We find that (i) counterintuitively, the synchronization improves significantly when θ(R) decreases, (ii) there exists a critical restricted angle θ(Rc) at which the synchronization order parameter changes from a large value to a small value, and (iii) for each noise amplitude η, the synchronization as a function of θ(R) shows a maximum value, indicating the existence of an optimal θ(R) that yields the best synchronization for every η.

Role of Gamma-Band Synchronization in Priming of Form Discrimination for Multiobject Displays

ERIC Educational Resources Information Center

Lu, Hongjing; Morrison, Robert G.; Hummel, John E.; Holyoak, Keith J.

2006-01-01

Previous research has shown that synchronized flicker can facilitate detection of a single Kanizsa square. The present study investigated the role of temporally structured priming in discrimination tasks involving perceptual relations between multiple Kanizsa-type figures. Results indicate that visual information presented as temporally structured…

An Online Synchronous Test for Professional Interpreters

ERIC Educational Resources Information Center

Chen, Nian-Shing; Ko, Leong

2010-01-01

This article is based on an experiment designed to conduct an interpreting test for multiple candidates online, using web-based synchronous cyber classrooms. The test model was based on the accreditation test for Professional Interpreters produced by the National Accreditation Authority of Translators and Interpreters (NAATI) in Australia.…

Synchronization in Scratch: A Case Study with Education Science Students

ERIC Educational Resources Information Center

Nikolos, Dimitris; Komis, Vassilis

2015-01-01

The Scratch programming language is an introductory programming language for students. It is also a visual concurrent programming language, where multiple threads are executed simultaneously. Synchronization in concurrent languages is a complex task for novices to understand. Our research is focused on strategies and methods applied by novice…

Incidence and risk factors of synchronous colorectal cancer in patients with esophageal cancer: an analysis of 480 consecutive colonoscopies before surgery.

PubMed

Yoshida, Naoya; Tamaoki, Yuka; Baba, Yoshifumi; Sakamoto, Yasuo; Miyamoto, Yuji; Iwatsuki, Masaaki; Shono, Takashi; Miyamoto, Hideaki; Imuta, Masanori; Kurashige, Junji; Sawayama, Hiroshi; Tokunaga, Ryuma; Watanabe, Masayuki; Sasaki, Yutaka; Yamashita, Yasuyuki; Baba, Hideo

2016-12-01

The precise incidence rates of multiple primary colorectal cancers in esophageal cancer patients are unknown. In total, 480 consecutive patients with esophageal cancers surgically resected in the Kumamoto University Hospital received preoperative total colonoscopy for the assessment of colorectal disease between April 2005 and February 2016. We retrospectively investigated the occurrence of synchronous colorectal cancer with esophageal cancer. In addition, we examined the risk factors for the incidence of multiple primary colorectal cancers. Of the 480 patients, 14 (2.9 %) had synchronous colorectal cancers, 13 had well-differentiated tubular adenocarcinomas, and 1 had papillary adenocarcinoma. Other 14 patients had metachronous colorectal cancer. The current incidence rates of synchronous and total (both synchronous and metachronous) colorectal cancers outnumbered those in normal healthy population and those in esophageal cancer patients which previously reported by The Japan Esophageal Society. The age ≥70 years (hazard ratio 4.82, 95 % confidence interval 1.473-15.78; p = 0.009) and Brinkman index ≥800 (hazard ratio 3.47, 95 % confidence interval 1.056-11.37; p = 0.040) were the independent risk factors for the incidence of synchronous colorectal cancer. They were also the independent risk factors for the incidence of total colorectal cancer. The results of the present study suggested that pretreatment screening with total colonoscopy is meaningful for patients with esophageal cancer, because the frequency of synchronous colorectal cancer was not negligible. Particularly, in patients >70 years and with history of heavy smoking, pretreatment colonoscopy might be necessary.

Finite Time Control Design for Bilateral Teleoperation System With Position Synchronization Error Constrained.

PubMed

Yang, Yana; Hua, Changchun; Guan, Xinping

2016-03-01

Due to the cognitive limitations of the human operator and lack of complete information about the remote environment, the work performance of such teleoperation systems cannot be guaranteed in most cases. However, some practical tasks conducted by the teleoperation system require high performances, such as tele-surgery needs satisfactory high speed and more precision control results to guarantee patient' health status. To obtain some satisfactory performances, the error constrained control is employed by applying the barrier Lyapunov function (BLF). With the constrained synchronization errors, some high performances, such as, high convergence speed, small overshoot, and an arbitrarily predefined small residual constrained synchronization error can be achieved simultaneously. Nevertheless, like many classical control schemes only the asymptotic/exponential convergence, i.e., the synchronization errors converge to zero as time goes infinity can be achieved with the error constrained control. It is clear that finite time convergence is more desirable. To obtain a finite-time synchronization performance, the terminal sliding mode (TSM)-based finite time control method is developed for teleoperation system with position error constrained in this paper. First, a new nonsingular fast terminal sliding mode (NFTSM) surface with new transformed synchronization errors is proposed. Second, adaptive neural network system is applied for dealing with the system uncertainties and the external disturbances. Third, the BLF is applied to prove the stability and the nonviolation of the synchronization errors constraints. Finally, some comparisons are conducted in simulation and experiment results are also presented to show the effectiveness of the proposed method.

Time synchronization of a frequency-hopped MFSK communication system

NASA Technical Reports Server (NTRS)

Simon, M. K.; Polydoros, A.; Huth, G. K.

1981-01-01

In a frequency-hopped (FH) multiple-frequency-shift-keyed (MFSK) communication system, frequency hopping causes the necessary frequency transitions for time synchronization estimation rather than the data sequence as in the conventional (nonfrequency-hopped) system. Making use of this observation, this paper presents a fine synchronization (i.e., time errors of less than a hop duration) technique for estimation of FH timing. The performance degradation due to imperfect FH time synchronization is found in terms of the effect on bit error probability as a function of full-band or partial-band noise jamming levels and of the number of hops used in the FH timing estimate.

Software Issues in High-Performance Computing and a Framework for the Development of HPC Applications

DTIC Science & Technology

1995-01-01

possible to determine communication points. For this version, a C program spawning Posix threads and using semaphores to synchronize would have to...performance such as the time required for network communication and synchronization as well as issues of asynchrony and memory hierarchy. For example...enhances reusability. Process (or task) parallel computations can also be succinctly expressed with a small set of process creation and synchronization

Dynamic Long-Term Anticipation of Chaotic States

DOE Office of Scientific and Technical Information (OSTI.GOV)

Voss, Henning U.

2001-07-02

Introducing a short time delay into the coupling of two synchronizing chaotic systems, it was shown recently that the driven system may anticipate the driving system in real time. Augmenting the phase space of the driven system, we accomplish anticipation times that are multiples of the coupling delay time and exceed characteristic time scales of the chaotic dynamics. The stability properties of the associated anticipatory synchronization manifold in certain cases turn out to be the same as for identically synchronizing oscillators.

Complex Synchronization Phenomena in Ecological Systems

NASA Astrophysics Data System (ADS)

Stone, Lewi; Olinky, Ronen; Blasius, Bernd; Huppert, Amit; Cazelles, Bernard

2002-07-01

Ecological and biological systems provide us with many striking examples of synchronization phenomena. Here we discuss a number of intriguing cases and attempt to explain them taking advantage of a modelling framework. One main focus will concern synchronized ecological end epidemiological cycles which have Uniform Phase growth associated with their regular recurrence, and Chaotic Amplitudes - a feature we term UPCA. Examples come from different areas and include decadal cycles of small mammals, recurrent viral epidemics such as childhood infections (eg., measles), and seasonally driven phytoplankton blooms observed in lakes and the oceans. A more detailed theoretical analysis of seasonally synchronized chaotic population cycles is presented.

Synchronization of unidirectionally delay-coupled chaotic oscillators with memory

NASA Astrophysics Data System (ADS)

Jaimes-Reátegui, Rider; Vera-Ávila, Victor P.; Sevilla-Escoboza, Ricardo; Huerta-Cuéllar, Guillermo; Castañeda-Hernández, Carlos E.; Chiu-Zarate, Roger; Pisarchik, Alexander N.

2016-11-01

We study synchronization of two chaotic oscillators coupled with time delay in a master-slave configuration and with delayed positive feedback in the slave oscillator which acts as memory. The dynamics of the slave oscillator is analyzed with bifurcation diagrams of the peak value of the system variable with respect to the coupling and feedback strengths and two delay times. For small coupling, when the oscillators' phases synchronize, memory can induce bistability and stabilize periodic orbits, whereas for stronger coupling it is not possible. The delayed feedback signal impairs synchronization, simultaneously enhancing coherence of the slave oscillator.

Laparoscopic resection of synchronous colorectal cancers in separate specimens.

PubMed

Inada, Ryo; Yamamoto, Seiichiro; Takawa, Masashi; Fujita, Shin; Akasu, Takayuki

2014-08-01

Laparoscopic approaches are increasingly being used in patients with colorectal cancer, but the feasibility of laparoscopic resection of synchronous colorectal cancers in separate specimens remains unknown. In such cases, it is necessary to consider the site of port placement, sequence of dissection, choice of specimen extraction sites, specimen handling, and extracorporeal anastomosis sites. Moreover, the need for complete mesenteric dissection in two areas, removal of two separate specimens containing malignancies, and two anastomoses elicit unique questions related to technical considerations. The aim of this study was to determine the feasibility of laparoscopic resection of two separate specimens containing malignancies for multiple synchronous colorectal cancers. Between June 2001 and January 2013, 1341 patients with colorectal cancer underwent laparoscopic surgery at our institution. Of them, 11 patients underwent laparoscopy-assisted combined resection of two separate colorectal specimens for multiple synchronous primary colorectal cancers. We retrospectively reviewed their surgical outcomes. All procedures were completed laparoscopically without perioperative mortality. Patients underwent right-sided colon resection for right-sided cancer and left-sided or rectal resection for left-sided colon or rectal cancer. The median duration of surgery was 296 min, and the median blood loss was 65 mL. Median time to first postoperative liquid and solid intake was 1 day and 3 days, respectively. Most patients were discharged on postoperative day 8. With regard to postoperative complications, two patients had a surgical-site infection. Laparoscopic resection of two separate colorectal specimens for multiple synchronous primary colorectal cancers is a feasible and safe procedure. © 2014 Japan Society for Endoscopic Surgery, Asia Endosurgery Task Force and Wiley Publishing Asia Pty Ltd.

Tight real-time synchronization of a microwave clock to an optical clock across a turbulent air path

PubMed Central

Bergeron, Hugo; Sinclair, Laura C.; Swann, William C.; Nelson, Craig W.; Deschênes, Jean-Daniel; Baumann, Esther; Giorgetta, Fabrizio R.; Coddington, Ian; Newbury, Nathan R.

2018-01-01

The ability to distribute the precise time and frequency from an optical clock to remote platforms could enable future precise navigation and sensing systems. Here we demonstrate tight, real-time synchronization of a remote microwave clock to a master optical clock over a turbulent 4-km open air path via optical two-way time-frequency transfer. Once synchronized, the 10-GHz frequency signals generated at each site agree to 10−14 at one second and below 10−17 at 1000 seconds. In addition, the two clock times are synchronized to ±13 fs over an 8-hour period. The ability to phase-synchronize 10-GHz signals across platforms supports future distributed coherent sensing, while the ability to time-synchronize multiple microwave-based clocks to a high-performance master optical clock supports future precision navigation/timing systems. PMID:29607352

Tight real-time synchronization of a microwave clock to an optical clock across a turbulent air path.

PubMed

Bergeron, Hugo; Sinclair, Laura C; Swann, William C; Nelson, Craig W; Deschênes, Jean-Daniel; Baumann, Esther; Giorgetta, Fabrizio R; Coddington, Ian; Newbury, Nathan R

2016-04-01

The ability to distribute the precise time and frequency from an optical clock to remote platforms could enable future precise navigation and sensing systems. Here we demonstrate tight, real-time synchronization of a remote microwave clock to a master optical clock over a turbulent 4-km open air path via optical two-way time-frequency transfer. Once synchronized, the 10-GHz frequency signals generated at each site agree to 10 -14 at one second and below 10 -17 at 1000 seconds. In addition, the two clock times are synchronized to ±13 fs over an 8-hour period. The ability to phase-synchronize 10-GHz signals across platforms supports future distributed coherent sensing, while the ability to time-synchronize multiple microwave-based clocks to a high-performance master optical clock supports future precision navigation/timing systems.

Fast sparsely synchronized brain rhythms in a scale-free neural network.

PubMed

Kim, Sang-Yoon; Lim, Woochang

2015-08-01

We consider a directed version of the Barabási-Albert scale-free network model with symmetric preferential attachment with the same in- and out-degrees and study the emergence of sparsely synchronized rhythms for a fixed attachment degree in an inhibitory population of fast-spiking Izhikevich interneurons. Fast sparsely synchronized rhythms with stochastic and intermittent neuronal discharges are found to appear for large values of J (synaptic inhibition strength) and D (noise intensity). For an intensive study we fix J at a sufficiently large value and investigate the population states by increasing D. For small D, full synchronization with the same population-rhythm frequency fp and mean firing rate (MFR) fi of individual neurons occurs, while for large D partial synchronization with fp>〈fi〉 (〈fi〉: ensemble-averaged MFR) appears due to intermittent discharge of individual neurons; in particular, the case of fp>4〈fi〉 is referred to as sparse synchronization. For the case of partial and sparse synchronization, MFRs of individual neurons vary depending on their degrees. As D passes a critical value D* (which is determined by employing an order parameter), a transition to unsynchronization occurs due to the destructive role of noise to spoil the pacing between sparse spikes. For D

Remote Sensing as a Demonstration of Applied Physics.

ERIC Educational Resources Information Center

Colwell, Robert N.

1980-01-01

Provides information about the field of remote sensing, including discussions of geo-synchronous and sun-synchronous remote-sensing platforms, the actual physical processes and equipment involved in sensing, the analysis of images by humans and machines, and inexpensive, small scale methods, including aerial photography. (CS)

Symmetries and stability of chimera states in small, globally-coupled networks

NASA Astrophysics Data System (ADS)

Hart, Joseph D.; Bansal, Kanika; Murphy, Thomas E.; Roy, Rajarshi

It has recently been demonstrated that symmetries in a network's topology can help predict the patterns of synchronized clusters that can emerge in a network of coupled oscillators. This and related discoveries have led to increased interest in both network symmetries and cluster synchronization. In parallel with these discoveries, interest in chimera states-dynamical patterns in which a network separates into coherent and incoherent portions-has grown, and chimeras have now been observed in a variety of experimental systems. We present an opto-electronic experiment in which both chimera states and synchronized clusters are observed in a small, globally-coupled network. We show that the symmetries and sub-symmetries of the network permit the formation of the chimera and cluster states. A recently developed group theoretical approach enables us to predict the stability of the observed chimera and cluster states, and highlights the close relationship between chimera and cluster states as belonging to the broader phenomenon of partial synchronization.

Uniting functional network topology and oscillations in the fronto-parietal single unit network of behaving primates.

PubMed

Dann, Benjamin; Michaels, Jonathan A; Schaffelhofer, Stefan; Scherberger, Hansjörg

2016-08-15

The functional communication of neurons in cortical networks underlies higher cognitive processes. Yet, little is known about the organization of the single neuron network or its relationship to the synchronization processes that are essential for its formation. Here, we show that the functional single neuron network of three fronto-parietal areas during active behavior of macaque monkeys is highly complex. The network was closely connected (small-world) and consisted of functional modules spanning these areas. Surprisingly, the importance of different neurons to the network was highly heterogeneous with a small number of neurons contributing strongly to the network function (hubs), which were in turn strongly inter-connected (rich-club). Examination of the network synchronization revealed that the identified rich-club consisted of neurons that were synchronized in the beta or low frequency range, whereas other neurons were mostly non-oscillatory synchronized. Therefore, oscillatory synchrony may be a central communication mechanism for highly organized functional spiking networks.

Mathematical foundations of hybrid data assimilation from a synchronization perspective

NASA Astrophysics Data System (ADS)

Penny, Stephen G.

2017-12-01

The state-of-the-art data assimilation methods used today in operational weather prediction centers around the world can be classified as generalized one-way coupled impulsive synchronization. This classification permits the investigation of hybrid data assimilation methods, which combine dynamic error estimates of the system state with long time-averaged (climatological) error estimates, from a synchronization perspective. Illustrative results show how dynamically informed formulations of the coupling matrix (via an Ensemble Kalman Filter, EnKF) can lead to synchronization when observing networks are sparse and how hybrid methods can lead to synchronization when those dynamic formulations are inadequate (due to small ensemble sizes). A large-scale application with a global ocean general circulation model is also presented. Results indicate that the hybrid methods also have useful applications in generalized synchronization, in particular, for correcting systematic model errors.

Mathematical foundations of hybrid data assimilation from a synchronization perspective.

PubMed

Penny, Stephen G

2017-12-01

The state-of-the-art data assimilation methods used today in operational weather prediction centers around the world can be classified as generalized one-way coupled impulsive synchronization. This classification permits the investigation of hybrid data assimilation methods, which combine dynamic error estimates of the system state with long time-averaged (climatological) error estimates, from a synchronization perspective. Illustrative results show how dynamically informed formulations of the coupling matrix (via an Ensemble Kalman Filter, EnKF) can lead to synchronization when observing networks are sparse and how hybrid methods can lead to synchronization when those dynamic formulations are inadequate (due to small ensemble sizes). A large-scale application with a global ocean general circulation model is also presented. Results indicate that the hybrid methods also have useful applications in generalized synchronization, in particular, for correcting systematic model errors.

A Spatiotemporal-Chaos-Based Cryptosystem Taking Advantage of Both Synchronous and Self-Synchronizing Schemes

NASA Astrophysics Data System (ADS)

Lü, Hua-Ping; Wang, Shi-Hong; Li, Xiao-Wen; Tang, Guo-Ning; Kuang, Jin-Yu; Ye, Wei-Ping; Hu, Gang

2004-06-01

Two-dimensional one-way coupled map lattices are used for cryptography where multiple space units produce chaotic outputs in parallel. One of the outputs plays the role of driving for synchronization of the decryption system while the others perform the function of information encoding. With this separation of functions the receiver can establish a self-checking and self-correction mechanism, and enjoys the advantages of both synchronous and self-synchronizing schemes. A comparison between the present system with the system of advanced encryption standard (AES) is presented in the aspect of channel noise influence. Numerical investigations show that our system is much stronger than AES against channel noise perturbations, and thus can be better used for secure communications with large channel noise.

Factors predictive of immediate breast reconstruction following mastectomy for invasive breast cancer in Australia.

PubMed

Roder, D; Zorbas, H; Kollias, J; Pyke, C; Walters, D; Campbell, I; Taylor, C; Webster, F

2013-12-01

To investigate person, cancer and treatment determinants of immediate breast reconstruction (IBR) in Australia. Bi-variable and multi-variable analyses of the Quality Audit database. Of 12,707 invasive cancers treated by mastectomy circa 1998-2010, 8% had IBR. This proportion increased over time and reduced from 29% in women below 30 years to approximately 1% in those aged 70 years or more. Multiple regression indicated that other IBR predictors included: high socio-economic status; private health insurance; being asymptomatic; a metropolitan rather than inner regional treatment centre; higher surgeon case load; small tumour size; negative nodal status, positive progesterone receptor status; more cancer foci; multiple affected breast quadrants; synchronous bilateral cancer; not having neo-adjuvant chemotherapy, adjuvant radiotherapy or adjuvant hormone therapy; and receiving ovarian ablation. Variations in access to specialty services and other possible causes of variations in IBR rates need further investigation. Copyright © 2013 Elsevier Ltd. All rights reserved.

Petrogenesis of the Elephant Moraine A79001 meteorite Multiple magma pulses on the shergottite parent body

NASA Technical Reports Server (NTRS)

Mcsween, H. Y., Jr.; Jarosewich, E.

1983-01-01

The EETA 79001 achondrite consists of two distinct igneous lithologies joined along a planar, non-brecciated contact. Both are basaltic rocks composed primarily of pigeonite, augite, and maskelynite, but one contains zoned megacrysts of olivine, orthopyroxene, and chromite that represent disaggregated xenoliths of harzburzite. Both lithologies probably formed from successive volcanic flows or multiple injections of magma into a small, shallow chamber. Many similarities between the two virtually synchronous magmas suggest that they are related. Possible mechanisms to explain their differences involve varying degrees of assimilation, fractionation from similar parental magmas, or partial melting of a similar source peridotite; of these, assimilation of the observed megacryst assemblage seems most plausible. However, some isotopic contamination may be required in any of these petrogenetic models. The meteorite has suffered extensive shock metamorphism and localized melting during a large impact event that probably excavated and liberated it from its parent body.

Brain connectivity analysis from EEG signals using stable phase-synchronized states during face perception tasks

NASA Astrophysics Data System (ADS)

Jamal, Wasifa; Das, Saptarshi; Maharatna, Koushik; Pan, Indranil; Kuyucu, Doga

2015-09-01

Degree of phase synchronization between different Electroencephalogram (EEG) channels is known to be the manifestation of the underlying mechanism of information coupling between different brain regions. In this paper, we apply a continuous wavelet transform (CWT) based analysis technique on EEG data, captured during face perception tasks, to explore the temporal evolution of phase synchronization, from the onset of a stimulus. Our explorations show that there exists a small set (typically 3-5) of unique synchronized patterns or synchrostates, each of which are stable of the order of milliseconds. Particularly, in the beta (β) band, which has been reported to be associated with visual processing task, the number of such stable states has been found to be three consistently. During processing of the stimulus, the switching between these states occurs abruptly but the switching characteristic follows a well-behaved and repeatable sequence. This is observed in a single subject analysis as well as a multiple-subject group-analysis in adults during face perception. We also show that although these patterns remain topographically similar for the general category of face perception task, the sequence of their occurrence and their temporal stability varies markedly between different face perception scenarios (stimuli) indicating toward different dynamical characteristics for information processing, which is stimulus-specific in nature. Subsequently, we translated these stable states into brain complex networks and derived informative network measures for characterizing the degree of segregated processing and information integration in those synchrostates, leading to a new methodology for characterizing information processing in human brain. The proposed methodology of modeling the functional brain connectivity through the synchrostates may be viewed as a new way of quantitative characterization of the cognitive ability of the subject, stimuli and information integration/segregation capability.

Experimental synchronization of chaos in a large ring of mutually coupled single-transistor oscillators: Phase, amplitude, and clustering effects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Minati, Ludovico, E-mail: lminati@ieee.org, E-mail: ludovico.minati@unitn.it

In this paper, experimental evidence of multiple synchronization phenomena in a large (n = 30) ring of chaotic oscillators is presented. Each node consists of an elementary circuit, generating spikes of irregular amplitude and comprising one bipolar junction transistor, one capacitor, two inductors, and one biasing resistor. The nodes are mutually coupled to their neighbours via additional variable resistors. As coupling resistance is decreased, phase synchronization followed by complete synchronization is observed, and onset of synchronization is associated with partial synchronization, i.e., emergence of communities (clusters). While component tolerances affect community structure, the general synchronization properties are maintained across three prototypes andmore » in numerical simulations. The clusters are destroyed by adding long distance connections with distant notes, but are otherwise relatively stable with respect to structural connectivity changes. The study provides evidence that several fundamental synchronization phenomena can be reliably observed in a network of elementary single-transistor oscillators, demonstrating their generative potential and opening way to potential applications of this undemanding setup in experimental modelling of the relationship between network structure, synchronization, and dynamical properties.« less

Squeezing Enhances Quantum Synchronization.

PubMed

Sonar, Sameer; Hajdušek, Michal; Mukherjee, Manas; Fazio, Rosario; Vedral, Vlatko; Vinjanampathy, Sai; Kwek, Leong-Chuan

2018-04-20

It is desirable to observe synchronization of quantum systems in the quantum regime, defined by the low number of excitations and a highly nonclassical steady state of the self-sustained oscillator. Several existing proposals of observing synchronization in the quantum regime suffer from the fact that the noise statistics overwhelm synchronization in this regime. Here, we resolve this issue by driving a self-sustained oscillator with a squeezing Hamiltonian instead of a harmonic drive and analyze this system in the classical and quantum regime. We demonstrate that strong entrainment is possible for small values of squeezing, and in this regime, the states are nonclassical. Furthermore, we show that the quality of synchronization measured by the FWHM of the power spectrum is enhanced with squeezing.

Squeezing Enhances Quantum Synchronization

NASA Astrophysics Data System (ADS)

Sonar, Sameer; Hajdušek, Michal; Mukherjee, Manas; Fazio, Rosario; Vedral, Vlatko; Vinjanampathy, Sai; Kwek, Leong-Chuan

2018-04-01

It is desirable to observe synchronization of quantum systems in the quantum regime, defined by the low number of excitations and a highly nonclassical steady state of the self-sustained oscillator. Several existing proposals of observing synchronization in the quantum regime suffer from the fact that the noise statistics overwhelm synchronization in this regime. Here, we resolve this issue by driving a self-sustained oscillator with a squeezing Hamiltonian instead of a harmonic drive and analyze this system in the classical and quantum regime. We demonstrate that strong entrainment is possible for small values of squeezing, and in this regime, the states are nonclassical. Furthermore, we show that the quality of synchronization measured by the FWHM of the power spectrum is enhanced with squeezing.

Cochlear spike synchronization and neuron coincidence detection model

NASA Astrophysics Data System (ADS)

Bader, Rolf

2018-02-01

Coincidence detection of a spike pattern fed from the cochlea into a single neuron is investigated using a physical Finite-Difference model of the cochlea and a physiologically motivated neuron model. Previous studies have shown experimental evidence of increased spike synchronization in the nucleus cochlearis and the trapezoid body [Joris et al., J. Neurophysiol. 71(3), 1022-1036 and 1037-1051 (1994)] and models show tone partial phase synchronization at the transition from mechanical waves on the basilar membrane into spike patterns [Ch. F. Babbs, J. Biophys. 2011, 435135]. Still the traveling speed of waves on the basilar membrane cause a frequency-dependent time delay of simultaneously incoming sound wavefronts up to 10 ms. The present model shows nearly perfect synchronization of multiple spike inputs as neuron outputs with interspike intervals (ISI) at the periodicity of the incoming sound for frequencies from about 30 to 300 Hz for two different amounts of afferent nerve fiber neuron inputs. Coincidence detection serves here as a fusion of multiple inputs into one single event enhancing pitch periodicity detection for low frequencies, impulse detection, or increased sound or speech intelligibility due to dereverberation.

Influence of stochastic perturbations on the cluster explosive synchronization of second-order Kuramoto oscillators on networks.

PubMed

Cao, Liang; Tian, Changhai; Wang, Zhenhua; Zhang, Xiyun; Liu, Zonghua

2018-02-01

Explosive synchronization in networked second-order Kuramoto oscillators has been well studied recently and it is revealed that the synchronization process is featured by cluster explosive synchronization. However, little attention has been paid to the influence of noise or perturbation. We here study this problem and discuss the influences of noise and perturbation. For the former, we interestingly find that noise has significant influence on the cluster explosive synchronization of those nodes with smaller degrees, i.e., their synchronization will change from the first-order to second-order transition and the critical points for both the forward and backward synchronization depend on the strength of noise. Especially, when the strength of noise is in an optimal range, a synchronization of the nodes with smaller degrees will be induced in the region of coupling strength where they do not display synchronization in the absence of noise. For the latter, we find that the effect of perturbation is similar to that of noise when its duration W is small. However, the perturbation will induce a change from cluster explosive synchronization to explosive synchronization when W is large. Furthermore, a brief theory is provided to explain the influence of perturbations on the critical points.

Synchronization and an application of a novel fractional order King Cobra chaotic system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Muthukumar, P., E-mail: muthukumardgl@gmail.com; Balasubramaniam, P., E-mail: balugru@gmail.com; Ratnavelu, K., E-mail: kuru052001@gmail.com

2014-09-01

In this paper, we design a new three dimensional King Cobra face shaped fractional order chaotic system. The multi-scale synchronization scheme of two fractional order chaotic systems is described. The necessary conditions for the multi-scale synchronization of two identical fractional order King Cobra chaotic systems are derived through feedback control. A new cryptosystem is proposed for an image encryption and decryption by using synchronized fractional order King Cobra chaotic systems with the supports of multiple cryptographic assumptions. The security of the proposed cryptosystem is analyzed by the well known algebraic attacks. Numerical simulations are given to show the effectiveness ofmore » the proposed theoretical results.« less

Local complexity predicts global synchronization of hierarchically networked oscillators

NASA Astrophysics Data System (ADS)

Xu, Jin; Park, Dong-Ho; Jo, Junghyo

2017-07-01

We study the global synchronization of hierarchically-organized Stuart-Landau oscillators, where each subsystem consists of three oscillators with activity-dependent couplings. We considered all possible coupling signs between the three oscillators, and found that they can generate different numbers of phase attractors depending on the network motif. Here, the subsystems are coupled through mean activities of total oscillators. Under weak inter-subsystem couplings, we demonstrate that the synchronization between subsystems is highly correlated with the number of attractors in uncoupled subsystems. Among the network motifs, perfect anti-symmetric ones are unique to generate both single and multiple attractors depending on the activities of oscillators. The flexible local complexity can make global synchronization controllable.

Online Moderation of Synchronous E-Argumentation

ERIC Educational Resources Information Center

Asterhan, Christa S. C.; Schwarz, Baruch B.

2010-01-01

In this paper, we present findings on moderation of synchronous, small-group argumentation in blended, co-located learning environments. Drawing on findings from the literature on human facilitation of dialogue in face-to-face settings, we first elaborate on the potential promise of this new practice. However, little is known about what…

A network of networks model to study phase synchronization using structural connection matrix of human brain

NASA Astrophysics Data System (ADS)

Ferrari, F. A. S.; Viana, R. L.; Reis, A. S.; Iarosz, K. C.; Caldas, I. L.; Batista, A. M.

2018-04-01

The cerebral cortex plays a key role in complex cortical functions. It can be divided into areas according to their function (motor, sensory and association areas). In this paper, the cerebral cortex is described as a network of networks (cortex network), we consider that each cortical area is composed of a network with small-world property (cortical network). The neurons are assumed to have bursting properties with the dynamics described by the Rulkov model. We study the phase synchronization of the cortex network and the cortical networks. In our simulations, we verify that synchronization in cortex network is not homogeneous. Besides, we focus on the suppression of neural phase synchronization. Synchronization can be related to undesired and pathological abnormal rhythms in the brain. For this reason, we consider the delayed feedback control to suppress the synchronization. We show that delayed feedback control is efficient to suppress synchronous behavior in our network model when an appropriate signal intensity and time delay are defined.

Synchronic nasopharyngeal and intraparotid warthin tumors: A case report and literature review.

PubMed

Yáñez-Barraza, Karina-Lizbeth; Domínguez-Malagon, Hugo-Ricardo; Mosqueda-Taylor, Adalberto; Cano-Valdez, Ana-María; Luna-Ortiz, Kuauhyama

2014-10-01

Warthin tumor is the second most frequent benign salivary gland tumor after pleomorphic adenoma; it occurs almost exclusively in the parotid gland and peri-parotideal lymph nodes, although it may rarely present in other locations. It may be multicentric and bilateral in a small percentage of cases. Nasopharyngeal Warthin tumor is very rare, and the presence of a synchronic WT involving nasopharynx and parotid is an exceptional event, as it has been described only twice in the literature. In this article we report an additional case of a synchronic Warthin tumor and review the related literature. Key words:Warthin tumor, synchronic WT, multicéntrico, nasopharynx.

Noise-Induced Synchronization among Sub-RF CMOS Analog Oscillators for Skew-Free Clock Distribution

NASA Astrophysics Data System (ADS)

Utagawa, Akira; Asai, Tetsuya; Hirose, Tetsuya; Amemiya, Yoshihito

We present on-chip oscillator arrays synchronized by random noises, aiming at skew-free clock distribution on synchronous digital systems. Nakao et al. recently reported that independent neural oscillators can be synchronized by applying temporal random impulses to the oscillators [1], [2]. We regard neural oscillators as independent clock sources on LSIs; i. e., clock sources are distributed on LSIs, and they are forced to synchronize through the use of random noises. We designed neuron-based clock generators operating at sub-RF region (<1GHz) by modifying the original neuron model to a new model that is suitable for CMOS implementation with 0.25-μm CMOS parameters. Through circuit simulations, we demonstrate that i) the clock generators are certainly synchronized by pseudo-random noises and ii) clock generators exhibited phase-locked oscillations even if they had small device mismatches.

Lynch syndrome-related small intestinal adenocarcinomas.

PubMed

Jun, Sun-Young; Lee, Eui-Jin; Kim, Mi-Ju; Chun, Sung Min; Bae, Young Kyung; Hong, Soon Uk; Choi, Jene; Kim, Joon Mee; Jang, Kee-Taek; Kim, Jung Yeon; Kim, Gwang Il; Jung, Soo Jin; Yoon, Ghilsuk; Hong, Seung-Mo

2017-03-28

Lynch syndrome is an autosomal-dominant disorder caused by defective DNA mismatch repair (MMR) genes and is associated with increased risk of malignancies in multiple organs. Small-intestinal adenocarcinomas are common initial manifestations of Lynch syndrome. To define the incidence and characteristics of Lynch syndrome-related small-intestinal adenocarcinomas, meticulous familial and clinical histories were obtained from 195 patients with small-intestinal adenocarcinoma, and MMR protein immunohistochemistry, microsatellite instability, MLH1 methylation, and germline mutational analyses were performed. Lynch syndrome was confirmed in eight patients (4%), all of whom had synchronous/metachronous malignancies without noticeable familial histories. Small-intestinal adenocarcinomas were the first clinical manifestation in 37% (3/8) of Lynch syndrome patients, and second malignancies developed within 5 years in 63% (5/8). The patients with accompanying Lynch syndrome were younger (≤50 years; P=0.04) and more likely to have mucinous adenocarcinomas (P=0.003), and tended to survive longer (P=0.11) than those with sporadic cases. A meticulous patient history taking, MMR protein immunolabeling, and germline MMR gene mutational analysis are important for the diagnosis of Lynch syndrome-related small-intestinal adenocarcinomas. Identifying Lynch syndrome in patients with small-intestinal adenocarcinoma can be beneficial for the early detection and treatment of additional Lynch syndrome-related cancers, especially in patients who are young or have mucinous adenocarcinomas.

Lynch syndrome-related small intestinal adenocarcinomas

PubMed Central

Jun, Sun-Young; Lee, Eui-Jin; Kim, Mi-Ju; Chun, Sung Min; Bae, Young Kyung; Hong, Soon Uk; Choi, Jene; Kim, Joon Mee; Jang, Kee-Taek; Kim, Jung Yeon; Kim, Gwang Il; Jung, Soo Jin; Yoon, Ghilsuk; Hong, Seung-Mo

2017-01-01

Lynch syndrome is an autosomal-dominant disorder caused by defective DNA mismatch repair (MMR) genes and is associated with increased risk of malignancies in multiple organs. Small-intestinal adenocarcinomas are common initial manifestations of Lynch syndrome. To define the incidence and characteristics of Lynch syndrome-related small-intestinal adenocarcinomas, meticulous familial and clinical histories were obtained from 195 patients with small-intestinal adenocarcinoma, and MMR protein immunohistochemistry, microsatellite instability, MLH1 methylation, and germline mutational analyses were performed. Lynch syndrome was confirmed in eight patients (4%), all of whom had synchronous/metachronous malignancies without noticeable familial histories. Small-intestinal adenocarcinomas were the first clinical manifestation in 37% (3/8) of Lynch syndrome patients, and second malignancies developed within 5 years in 63% (5/8). The patients with accompanying Lynch syndrome were younger (≤50 years; P=0.04) and more likely to have mucinous adenocarcinomas (P=0.003), and tended to survive longer (P=0.11) than those with sporadic cases. A meticulous patient history taking, MMR protein immunolabeling, and germline MMR gene mutational analysis are important for the diagnosis of Lynch syndrome-related small-intestinal adenocarcinomas. Identifying Lynch syndrome in patients with small-intestinal adenocarcinoma can be beneficial for the early detection and treatment of additional Lynch syndrome-related cancers, especially in patients who are young or have mucinous adenocarcinomas. PMID:28206961

A Production System Version of the Hearsay-II Speech Understanding System

DTIC Science & Technology

1978-04-01

synchronization mechanisms turn out to be adequate with a rull complement of KSs. Finally, HSP is found to aid solution of the Small Address Problem, as it...much greater than that if HSP’s less powerful synchronization mechanisms turn out to be adequate with a full complement of KSs. Finally, HSP is...earlier version of HSII which had a limited set of KSs. With a richer set of KSs and/or a reduction (or elimination) of synchronization overheads, the

Synchronization of chaotic and nonchaotic oscillators: Application to bipolar disorder

NASA Astrophysics Data System (ADS)

Nono Dueyou Buckjohn, C.; Siewe Siewe, M.; Tchawoua, C.; Kofane, T. C.

2010-08-01

In this Letter, we use a synchronization scheme on two bipolar disorder models consisting of a strong nonlinear system with multiplicative excitation and a nonlinear oscillator without parametric harmonic forcing. The stability condition following our control function is analytically demonstrated using the Lyapunov theory and Routh-Hurwitz criteria, we then have the condition for the existence of a feedback gain matrix. A convenient demonstration of the accuracy of the method is complemented by the numerical simulations from which we illustrate the synchronized dynamics between the two non-identical bipolar disorder patients.

Distributed attitude synchronization of formation flying via consensus-based virtual structure

NASA Astrophysics Data System (ADS)

Cong, Bing-Long; Liu, Xiang-Dong; Chen, Zhen

2011-06-01

This paper presents a general framework for synchronized multiple spacecraft rotations via consensus-based virtual structure. In this framework, attitude control systems for formation spacecrafts and virtual structure are designed separately. Both parametric uncertainty and external disturbance are taken into account. A time-varying sliding mode control (TVSMC) algorithm is designed to improve the robustness of the actual attitude control system. As for the virtual attitude control system, a behavioral consensus algorithm is presented to accomplish the attitude maneuver of the entire formation and guarantee a consistent attitude among the local virtual structure counterparts during the attitude maneuver. A multiple virtual sub-structures (MVSSs) system is introduced to enhance current virtual structure scheme when large amounts of spacecrafts are involved in the formation. The attitude of spacecraft is represented by modified Rodrigues parameter (MRP) for its non-redundancy. Finally, a numerical simulation with three synchronization situations is employed to illustrate the effectiveness of the proposed strategy.

Predator-induced synchrony in population oscillations of coexisting small mammal species.

PubMed

Korpimäki, Erkki; Norrdahl, Kai; Huitu, Otso; Klemola, Tero

2005-01-22

Comprehensive analyses of long-term (1977-2003) small-mammal abundance data from western Finland showed that populations of Microtus voles (field voles M. agrestis and sibling voles M. rossiaemeridionalis) voles, bank (Clethrionomys glareolus) and common shrews (Sorex araneus) fluctuated synchronously in 3 year population cycles. Time-series analyses indicated that interspecific synchrony is influenced strongly by density-dependent processes. Synchrony among Microtus and bank voles appeared additionally to be influenced by density-independent processes. To test whether interspecific synchronization through density-dependent processes is caused by predation, we experimentally reduced the densities of the main predators of small mammals in four large agricultural areas, and compared small mammal abundances in these to those in four control areas (2.5-3 km(2)) through a 3 year small-mammal population cycle. Predator reduction increased densities of the main prey species, Microtus voles, in all phases of the population cycle, while bank voles, the most important alternative prey of predators, responded positively only in the low and the increase phase. Manipulation also increased the autumn densities of water voles (Arvicola terrestris) in the increase phase of the cycle. No treatment effects were detected for common shrews or mice. Our results are in accordance with the alternative prey hypothesis, by which predators successively reduce the densities of both main and alternative prey species after the peak phase of small-mammal population cycles, thus inducing a synchronous low phase.

On the spin states of habitable zone exoplanets around M dwarfs: the effect of a near-resonant companion

NASA Astrophysics Data System (ADS)

Vinson, Alec M.; Hansen, Brad M. S.

2017-12-01

One long-standing problem for the potential habitability of planets within M dwarf systems is their likelihood to be tidally locked in a synchronously rotating spin state. This problem thus far has largely been addressed only by considering two objects: the star and the planet itself. However, many systems have been found to harbour multiple planets, with some in or very near to mean motion resonances. The presence of a planetary companion near a mean motion resonance can induce oscillatory variations in the mean motion of the planet, which we demonstrate can have significant effects on the spin state of an otherwise synchronously rotating planet. In particular, we find that a planetary companion near a mean motion resonance can excite the spin states of planets in the habitable zone of small, cool stars, pushing otherwise synchronously rotating planets into higher amplitude librations of the spin state, or even complete circulation resulting in effective stellar days with full surface coverage on the order of years or decades. This increase in illuminated area can have potentially dramatic influences on climate, and thus on habitability. We also find that the resultant spin state can be very sensitive to initial conditions due to the chaotic nature of the spin state at early times within certain regimes. We apply our model to two hypothetical planetary systems inspired by the K00255 and TRAPPIST-1 systems, both of which have Earth-sized planets in mean motion resonances orbiting cool stars.

A Data Hiding Technique to Synchronously Embed Physiological Signals in H.264/AVC Encoded Video for Medicine Healthcare.

PubMed

Peña, Raul; Ávila, Alfonso; Muñoz, David; Lavariega, Juan

2015-01-01

The recognition of clinical manifestations in both video images and physiological-signal waveforms is an important aid to improve the safety and effectiveness in medical care. Physicians can rely on video-waveform (VW) observations to recognize difficult-to-spot signs and symptoms. The VW observations can also reduce the number of false positive incidents and expand the recognition coverage to abnormal health conditions. The synchronization between the video images and the physiological-signal waveforms is fundamental for the successful recognition of the clinical manifestations. The use of conventional equipment to synchronously acquire and display the video-waveform information involves complex tasks such as the video capture/compression, the acquisition/compression of each physiological signal, and the video-waveform synchronization based on timestamps. This paper introduces a data hiding technique capable of both enabling embedding channels and synchronously hiding samples of physiological signals into encoded video sequences. Our data hiding technique offers large data capacity and simplifies the complexity of the video-waveform acquisition and reproduction. The experimental results revealed successful embedding and full restoration of signal's samples. Our results also demonstrated a small distortion in the video objective quality, a small increment in bit-rate, and embedded cost savings of -2.6196% for high and medium motion video sequences.

Self-organizing plasma behavior in multiple grid IEC fusion devices for propulsion

NASA Astrophysics Data System (ADS)

McGuire, Thomas; Dietrich, Carl; Sedwick, Raymond

2004-11-01

Inertial Electrostatic Confinement, IEC, of charged particles for the purpose of producing fusion energy is a low mass alternative to more traditional magnetic and inertial confinement fusion schemes. Experimental fusion production and energy efficiency in IEC devices to date has been hindered by confinement limitations. Analysis of the major loss mechanisms suggests that the low pressure beam-beam interaction regime holds the most promise for improved efficiency operation. Numerical simulation of multiple grid schemes shows greatly increased confinement times over contemporary single grid designs by electrostatic focusing of the ion beams. An analytical model of this focusing is presented. With the increased confinement, beams self-organize from a uniform condition into bunches that oscillate at the bounce frequency. The bunches from neighboring beams are then observed to synchronize with each other. Analysis of the anisotropic collisional dynamics responsible for the synchronization is presented. The importance of focusing and density on the beam dynamics are examined. Further, this synchronization appears to modify the particle distribution so as to maintain the non-maxwellian, beam-like energy profile within a bunch. The ability of synchronization to modify and counter-act the thermalization process is examined analytically at the 2-body interaction level and as a conglomeration of particles via numerical simulation. Detailed description of the experiment under development at MIT to investigate the synchronization phenomenon is presented.

E-Moderation of Synchronous Discussions in Educational Settings: A Nascent Practice

ERIC Educational Resources Information Center

Schwarz, Baruch B.; Asterhan, Christa S.

2011-01-01

E-moderation has been a common practice in asynchronous discussions of postsecondary courses. We consider here e-moderation of synchronous discussions in the school context. We adopt a design research approach to elaborate an environment, the Argunaut system, that fits the reality of classrooms in which moderation of several small-group…

An integrate-and-fire model for synchronized bursting in a network of cultured cortical neurons.

PubMed

French, D A; Gruenstein, E I

2006-12-01

It has been suggested that spontaneous synchronous neuronal activity is an essential step in the formation of functional networks in the central nervous system. The key features of this type of activity consist of bursts of action potentials with associated spikes of elevated cytoplasmic calcium. These features are also observed in networks of rat cortical neurons that have been formed in culture. Experimental studies of these cultured networks have led to several hypotheses for the mechanisms underlying the observed synchronized oscillations. In this paper, bursting integrate-and-fire type mathematical models for regular spiking (RS) and intrinsic bursting (IB) neurons are introduced and incorporated through a small-world connection scheme into a two-dimensional excitatory network similar to those in the cultured network. This computer model exhibits spontaneous synchronous activity through mechanisms similar to those hypothesized for the cultured experimental networks. Traces of the membrane potential and cytoplasmic calcium from the model closely match those obtained from experiments. We also consider the impact on network behavior of the IB neurons, the geometry and the small world connection scheme.

Uniting functional network topology and oscillations in the fronto-parietal single unit network of behaving primates

PubMed Central

Dann, Benjamin; Michaels, Jonathan A; Schaffelhofer, Stefan; Scherberger, Hansjörg

2016-01-01

The functional communication of neurons in cortical networks underlies higher cognitive processes. Yet, little is known about the organization of the single neuron network or its relationship to the synchronization processes that are essential for its formation. Here, we show that the functional single neuron network of three fronto-parietal areas during active behavior of macaque monkeys is highly complex. The network was closely connected (small-world) and consisted of functional modules spanning these areas. Surprisingly, the importance of different neurons to the network was highly heterogeneous with a small number of neurons contributing strongly to the network function (hubs), which were in turn strongly inter-connected (rich-club). Examination of the network synchronization revealed that the identified rich-club consisted of neurons that were synchronized in the beta or low frequency range, whereas other neurons were mostly non-oscillatory synchronized. Therefore, oscillatory synchrony may be a central communication mechanism for highly organized functional spiking networks. DOI: http://dx.doi.org/10.7554/eLife.15719.001 PMID:27525488

Thermodynamics aspects of noise-induced phase synchronization

NASA Astrophysics Data System (ADS)

Pinto, Pedro D.; Oliveira, Fernando A.; Penna, André L. A.

2016-05-01

In this article, we present an approach for the thermodynamics of phase oscillators induced by an internal multiplicative noise. We analytically derive the free energy, entropy, internal energy, and specific heat. In this framework, the formulation of the first law of thermodynamics requires the definition of a synchronization field acting on the phase oscillators. By introducing the synchronization field, we have consistently obtained the susceptibility and analyzed its behavior. This allows us to characterize distinct phases in the system, which we have denoted as synchronized and parasynchronized phases, in analogy with magnetism. The system also shows a rich complex behavior, exhibiting ideal gas characteristics for low temperatures and susceptibility anomalies that are similar to those present in complex fluids such as water.

Thermodynamics aspects of noise-induced phase synchronization.

PubMed

Pinto, Pedro D; Oliveira, Fernando A; Penna, André L A

2016-05-01

In this article, we present an approach for the thermodynamics of phase oscillators induced by an internal multiplicative noise. We analytically derive the free energy, entropy, internal energy, and specific heat. In this framework, the formulation of the first law of thermodynamics requires the definition of a synchronization field acting on the phase oscillators. By introducing the synchronization field, we have consistently obtained the susceptibility and analyzed its behavior. This allows us to characterize distinct phases in the system, which we have denoted as synchronized and parasynchronized phases, in analogy with magnetism. The system also shows a rich complex behavior, exhibiting ideal gas characteristics for low temperatures and susceptibility anomalies that are similar to those present in complex fluids such as water.

Synchronous glioblastoma multiforme and chondrosarcoma: A case report and review of the literature.

PubMed

Li, Charles Xin; Goldenberg, Yoni; McLean, Catriona; Savio Gomes, Keith

2018-06-01

This case report describes the rare occurrence of two individually uncommon tumours found in synchronous manner in an otherwise healthy patient with no history of malignancy. We believe this to be the first reported case of synchronous glioblastoma and chondrosarcoma. While primary rib lesions metastasising to brain are rarely reported and primary brain lesions metastasising to rib are even rarer still, there were no previous reports in the literature of synchronous brain and rib dual primary pathology that we could identify. Unrelated dual pathology, while rare, must be considered amongst the list of differential diagnoses in patients who present with multiple lesions, and highlights the importance of separate histological confirmation prior to integrated management. Copyright © 2018 Elsevier Ltd. All rights reserved.

Three-dimensional tracking of small aquatic organisms using fluorescent nanoparticles.

PubMed

Ekvall, Mikael T; Bianco, Giuseppe; Linse, Sara; Linke, Heiner; Bäckman, Johan; Hansson, Lars-Anders

2013-01-01

Tracking techniques are vital for the understanding of the biology and ecology of organisms. While such techniques have provided important information on the movement and migration of large animals, such as mammals and birds, scientific advances in understanding the individual behaviour and interactions of small (mm-scale) organisms have been hampered by constraints, such as the sizes of existing tracking devices, in existing tracking methods. By combining biology, chemistry and physics we here present a method that allows three-dimensional (3D) tracking of individual mm-sized aquatic organisms. The method is based on in-vivo labelling of the organisms with fluorescent nanoparticles, so-called quantum dots, and tracking of the organisms in 3D via the quantum-dot fluorescence using a synchronized multiple camera system. It allows for the efficient and simultaneous study of the behaviour of one as well as multiple individuals in large volumes of observation, thus enabling the study of behavioural interactions at the community scale. The method is non-perturbing - we demonstrate that the labelling is not affecting the behavioural response of the organisms - and is applicable over a wide range of taxa, including cladocerans as well as insects, suggesting that our methodological concept opens up for new research fields on individual behaviour of small animals. Hence, this offers opportunities to focus on important biological, ecological and behavioural questions never before possible to address.

Distributed Synchronization Technique for OFDMA-Based Wireless Mesh Networks Using a Bio-Inspired Algorithm

PubMed Central

Kim, Mi Jeong; Maeng, Sung Joon; Cho, Yong Soo

2015-01-01

In this paper, a distributed synchronization technique based on a bio-inspired algorithm is proposed for an orthogonal frequency division multiple access (OFDMA)-based wireless mesh network (WMN) with a time difference of arrival. The proposed time- and frequency-synchronization technique uses only the signals received from the neighbor nodes, by considering the effect of the propagation delay between the nodes. It achieves a fast synchronization with a relatively low computational complexity because it is operated in a distributed manner, not requiring any feedback channel for the compensation of the propagation delays. In addition, a self-organization scheme that can be effectively used to construct 1-hop neighbor nodes is proposed for an OFDMA-based WMN with a large number of nodes. The performance of the proposed technique is evaluated with regard to the convergence property and synchronization success probability using a computer simulation. PMID:26225974

Distributed Synchronization Technique for OFDMA-Based Wireless Mesh Networks Using a Bio-Inspired Algorithm.

PubMed

Kim, Mi Jeong; Maeng, Sung Joon; Cho, Yong Soo

2015-07-28

In this paper, a distributed synchronization technique based on a bio-inspired algorithm is proposed for an orthogonal frequency division multiple access (OFDMA)-based wireless mesh network (WMN) with a time difference of arrival. The proposed time- and frequency-synchronization technique uses only the signals received from the neighbor nodes, by considering the effect of the propagation delay between the nodes. It achieves a fast synchronization with a relatively low computational complexity because it is operated in a distributed manner, not requiring any feedback channel for the compensation of the propagation delays. In addition, a self-organization scheme that can be effectively used to construct 1-hop neighbor nodes is proposed for an OFDMA-based WMN with a large number of nodes. The performance of the proposed technique is evaluated with regard to the convergence property and synchronization success probability using a computer simulation.

Synchronic nasopharyngeal and intraparotid warthin tumors: A case report and literature review

PubMed Central

Domínguez-Malagon, Hugo-Ricardo; Mosqueda-Taylor, Adalberto; Cano-Valdez, Ana-María; Luna-Ortiz, Kuauhyama

2014-01-01

Warthin tumor is the second most frequent benign salivary gland tumor after pleomorphic adenoma; it occurs almost exclusively in the parotid gland and peri-parotideal lymph nodes, although it may rarely present in other locations. It may be multicentric and bilateral in a small percentage of cases. Nasopharyngeal Warthin tumor is very rare, and the presence of a synchronic WT involving nasopharynx and parotid is an exceptional event, as it has been described only twice in the literature. In this article we report an additional case of a synchronic Warthin tumor and review the related literature. Key words:Warthin tumor, synchronic WT, multicéntrico, nasopharynx. PMID:25593670

Motor run-up system. [power lines

NASA Technical Reports Server (NTRS)

Daeges, J. J. (Inventor)

1975-01-01

A starting system is described for bringing a large synchronous motor up to speed to prevent large power line disturbances at the moment the motor is connected to the power line. The system includes (1) a digital counter which generates a count determined by the difference in frequency between the power line and a small current generated by the synchronous motor; (2) a latch which stores the count; and (3) a comparator which compares the stored count with a newly generated count to determine whether the synchronous motor is accelerating or decelerating. Signals generated by the counter and comparator control the current to a clutch that couples a starting motor to the large synchronous motor.

Improvement of surgical margin with a coupled saline-radio-frequency device for multiple colorectal liver metastases.

PubMed

Ogata, Satoshi; Kianmanesh, Reza; Varma, Deepak; Belghiti, Jacques

2005-01-01

Complete resection of colorectal liver metastases (LM) has been the only curative treatment. However, when LM are multiple and bilobar, only a few patients are candidates for curative surgery. We report on a 53-year-old woman with synchronous multiple and bilobar LM from sigmoidal cancer who became resectable after a multimodal strategy including preoperative systemic chemotherapy and two-step surgery. The spectacular decrease in tumor size after systemic chemotherapy led us to perform two-step surgery, including right portal-vein ligation and left liver metastasectomies, with a coupled saline-radiofrequency device, in order to improve the surgical margin. An extended right hepatectomy was performed later to remove the remaining right liver lesions. The patient was discharged after 28 days without major complication and was recurrence-free 14 months later. We conclude that improving the surgical margin with a coupled saline-radiofrequency device is feasible and effective, avoiding small remnant liver even after multiple tumorectomies. The multimodal strategy, including preoperative chemotherapy, two-step surgery, and tumorectomies, using a coupled saline-radiofrequency device, could increase the number of patients with diffuse bilobar liver metastases who can benefit from liver resection.

Multiple Spatial Coherence Resonances and Spatial Patterns in a Noise-Driven Heterogeneous Neuronal Network

NASA Astrophysics Data System (ADS)

Li, Yu-Ye; Ding, Xue-Li

2014-12-01

Heterogeneity of the neurons and noise are inevitable in the real neuronal network. In this paper, Gaussian white noise induced spatial patterns including spiral waves and multiple spatial coherence resonances are studied in a network composed of Morris—Lecar neurons with heterogeneity characterized by parameter diversity. The relationship between the resonances and the transitions between ordered spiral waves and disordered spatial patterns are achieved. When parameter diversity is introduced, the maxima of multiple resonances increases first, and then decreases as diversity strength increases, which implies that the coherence degrees induced by noise are enhanced at an intermediate diversity strength. The synchronization degree of spatial patterns including ordered spiral waves and disordered patterns is identified to be a very low level. The results suggest that the nervous system can profit from both heterogeneity and noise, and the multiple spatial coherence resonances are achieved via the emergency of spiral waves instead of synchronization patterns.

Rupture Synchronicity in Complex Fault Systems

NASA Astrophysics Data System (ADS)

Milner, K. R.; Jordan, T. H.

2013-12-01

While most investigators would agree that the timing of large earthquakes within a fault system depends on stress-mediated interactions among its elements, much of the debate relevant to time-dependent forecasting has been centered on single-fault concepts, such as characteristic earthquake behavior. We propose to broaden this discussion by quantifying the multi-fault concept of rupture synchronicity. We consider a finite set of small, fault-spanning volumes {Vk} within a fault system of arbitrary (fractal) complexity. We let Ck be the catalog of length tmax comprising Nk discrete times {ti(k)} that mark when the kth volume participates in a rupture of magnitude > M. The main object of our analysis is the complete set of event time differences {τij(kk') = ti(k) - tj(k')}, which we take to be a random process with an expected density function ρkk'(t). When k = k', we call this function the auto-catalog density function (ACDF); when k ≠ k', we call it the cross-catalog density function (CCDF). The roles of the ACDF and CCDF in synchronicity theory are similar to those of autocorrelation and cross-correlation functions in time-series analysis. For a renewal process, the ACDF can be written in terms of convolutions of the interevent-time distribution, and many of its properties (e.g., large-t asymptote) can be derived analytically. The interesting information in the CCDF, like that in the ACDF, is concentrated near t = 0. If two catalogs are completely asynchronous, the CCDF collapses to an asymptote given by the harmonic mean of the ACDF asymptotes. Synchronicity can therefore be characterized by the variability of the CCDF about this asymptote. The brevity of instrumental catalogs makes the identification of synchronicity at large M difficult, but we will illustrate potentially interesting behaviors through the analysis of a million-year California catalog generated by the earthquake simulator, RSQSim (Deiterich & Richards-Dinger, 2010), which we sampled at a dozen fault-spanning volumes. At the magnitude threshold M = 7, the ACDF can be well fit by renewal models with fairly small aperiodicity parameters (α < 0.2) for all fault volumes but one (on the San Jacinto fault). At interseismic (Reid) time scales, we observe pairs of fault segments that are tightly locked, such as the Cholame and Carrizo sections of the San Andreas Fault (SAF), where the CCDF and two ACDFs are nearly equal; segments out of phase (Carrizo-SAF/Coachella-SAF and Coachella-SAF/San Jacinto), where the CCDF variation is an odd function of time; and segments where events are in phase with integer ratios of recurrence times (2:1 synchronicity of Coachella-SAF/Mojave-SAF and Carrizo-SAF/Mojave-SAF). At near-seismic (Omori) time scales, we observe various modes of clustering, triggering, and shadowing in RSQSim catalogs; e.g., events on Mojave-SAF trigger Garlock events, and events on Coachella-SAF shut down events on San Jacinto. Therefore, despite its geometrical complexity and multiplicity of time scales, the RSQSim model of the San Andreas fault system exhibits a variety of synchronous behaviors that increase the predictability of large ruptures within the system. A key question for earthquake forecasting is whether the real San Andreas system is equally, or much less, synchronous.

Noise and coupling induced synchronization in a network of chaotic neurons

NASA Astrophysics Data System (ADS)

Ciszak, Marzena; Euzzor, Stefano; Geltrude, Andrea; Tito Arecchi, F.; Meucci, Riccardo

2013-04-01

The synchronization in four forced FitzHugh-Nagumo (FHN) systems is studied, both experimentally and by numerical simulations of a model. We show that synchronization may be achieved either by coupling of systems through bidirectional diffusive interactions, by introducing a common noise to all systems or by combining both ingredients, noise and coupling together. Here we consider white and colored noises, showing that the colored noise is more efficient in synchronizing the systems respect to white noise. Moreover, a small addition of common noise allows the synchronization to occur at smaller values of the coupling strength. When the diffusive coupling in the absence of noise is considered, the system undergoes the transition to subthreshold oscillations, giving a spike suppression regime. We show that noise destroys the appearance of this dynamical regime induced by coupling.

Anticipated and zero-lag synchronization in motifs of delay-coupled systems

NASA Astrophysics Data System (ADS)

Mirasso, Claudio R.; Carelli, Pedro V.; Pereira, Tiago; Matias, Fernanda S.; Copelli, Mauro

2017-11-01

Anticipated and zero-lag synchronization have been observed in different scientific fields. In the brain, they might play a fundamental role in information processing, temporal coding and spatial attention. Recent numerical work on anticipated and zero-lag synchronization studied the role of delays. However, an analytical understanding of the conditions for these phenomena remains elusive. In this paper, we study both phenomena in systems with small delays. By performing a phase reduction and studying phase locked solutions, we uncover the functional relation between the delay, excitation and inhibition for the onset of anticipated synchronization in a sender-receiver-interneuron motif. In the case of zero-lag synchronization in a chain motif, we determine the stability conditions. These analytical solutions provide an excellent prediction of the phase-locked regimes of Hodgkin-Huxley models and Roessler oscillators.

Synchronization control in multiplex networks of nonlinear multi-agent systems

NASA Astrophysics Data System (ADS)

He, Wangli; Xu, Zhiwei; Du, Wenli; Chen, Guanrong; Kubota, Naoyuki; Qian, Feng

2017-12-01

This paper is concerned with synchronization control of a multiplex network, in which two different kinds of relationships among agents coexist. Hybrid coupling, including continuous linear coupling and impulsive coupling, is proposed to model the coexisting distinguishable interactions. First, by adding impulsive controllers on a small portion of agents, local synchronization is analyzed by linearizing the error system at the desired trajectory. Then, global synchronization is studied based on the Lyapunov stability theory, where a time-varying coupling strength is involved. To further deal with the time-varying coupling strength, an adaptive updating law is introduced and a corresponding sufficient condition is obtained to ensure synchronization of the multiplex network towards the desired trajectory. Networks of Chua's circuits and other chaotic systems with double layers of interactions are simulated to verify the proposed method.

Applications technology satellites advanced mission study

NASA Technical Reports Server (NTRS)

Gould, L. M.

1972-01-01

Three spacecraft configurations were designed for operation as a high powered synchronous communications satellite. Each spacecraft includes a 1 kw TWT and a 2 kw Klystron power amplifier feeding an antenna with multiple shaped beams. One of the spacecraft is designed to be boosted by a Thor-Delta launch vehicle and raised to synchronous orbit with electric propulsion. The other two are inserted into a elliptical transfer orbit with an Atlas Centaur and injected into final orbit with an apogee kick motor. Advanced technologies employed in the several configurations include tubes with multiple stage collectors radiating directly to space, multiple-contoured beam antennas, high voltage rollout solar cell arrays with integral power conditioning, electric propulsion for orbit raising and on-station attitude control and station-keeping, and liquid metal slip rings.

Synchronized Re-Entrant Flux Reversal of Multiple FeSiB Amorphous Wires Having the Larger Output

NASA Astrophysics Data System (ADS)

Takajo, Minoru; Yamasaki, Jiro

Technique to synchronize the re-entrant flux reversal of the multiple magnetostrictive Fe77.5Si7.5B15 amorphous wires was developed using a flux keeper of amorphous ribbons contacted to the wire ends. It is comprehended that the characteristics of the re-entrant flux takes place respectively at almost the same time in the three Fe-Si-B amorphous wires with a diameter of 65, 95μm. This phenomenon can be explained by considering the strong magnetic coupling of wires and amorphous ribbon by stray field from the each wire ends. As a result, the magnitude of the induced voltage in the sense coil is increased in proportion to the multiplication of the number of the wires.

Influence of Internal and External Noise on Spontaneous Visuomotor Synchronization.

PubMed

Varlet, Manuel; Schmidt, R C; Richardson, Michael J

2016-01-01

Historically, movement noise or variability is considered to be an undesirable property of biological motor systems. In particular, noise is typically assumed to degrade the emergence and stability of rhythmic motor synchronization. Recently, however, it has been suggested that small levels of noise might actually improve the functioning of motor systems and facilitate their adaptation to environmental events. Here, the authors investigated whether noise can facilitate spontaneous rhythmic visuomotor synchronization. They examined the influence of internal noise in the rhythmic limb movements of participants and external noise in the movement of an oscillating visual stimulus on the occurrence of spontaneous synchronization. By indexing the natural frequency variability of participants and manipulating the frequency variability of the visual stimulus, the authors demonstrated that both internal and external noise degrade synchronization when the participants' and stimulus movement frequencies are similar, but can actually facilitate synchronization when the frequencies are different. Furthermore, the two kinds of noise interact with each other. Internal noise facilitates synchronization only when external noise is minimal and vice versa. Too much internal and external noise together degrades synchronization. These findings open new perspectives for better understanding the role of noise in human rhythmic coordination.

Safety and benefit of curative surgical resection for esophageal squamous cell cancer associated with multiple primary cancers.

PubMed

Otowa, Y; Nakamura, T; Takiguchi, G; Yamamoto, M; Kanaji, S; Imanishi, T; Oshikiri, T; Suzuki, S; Tanaka, K; Kakeji, Y

2016-03-01

Enhancements in surgical techniques have led to improved outcomes for esophageal cancer. Recent findings have showed that esophageal cancer is frequently associated with multiple primary cancers, and surgical resection is usually complicated in such cases. The aim of this study was to clarify the clinical significance of surgery for patients with esophageal squamous cell cancer associated with multiple primary cancers. The clinical outcomes of surgical resection for esophageal cancer were compared among 79 patients with antecedent and/or synchronous cancers (Multiple cancer group) and 194 patients without antecedent and/or synchronous cancers (Single cancer group). The most common site of multiple primary cancers was the pharynx (36 patients; 29.7%), followed by the stomach (24 patients; 19.8%). The reconstruction method was more complicated in the Multiple cancer group as a result of the prolonged surgery time and increased blood loss. However, postoperative morbidity and overall survival (OS) did not differ between the two groups. After esophagectomy, metachronous cancers were observed in 26 patients, with 30 regions in total, and 93.1% were found to be curable. Sex was the only independent risk factors for developing metachronous cancer after esophagectomy. The presence of antecedent and synchronous cancers complicates the surgical resection of esophageal cancer; however, no differences were found in the OS and postoperative morbidity between the two groups. Therefore, surgical intervention should be selected as a first-line treatment. Because second primary cancers are often observed in esophageal cancer, we recommend a close follow-up using esophagogastroduodenoscopy and contrast-enhanced computed tomography. Copyright © 2015 Elsevier Ltd. All rights reserved.

Synchronization of spin-transfer torque oscillators by spin pumping, inverse spin Hall, and spin Hall effects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Elyasi, Mehrdad; Bhatia, Charanjit S.; Yang, Hyunsoo, E-mail: eleyang@nus.edu.sg

2015-02-14

We have proposed a method to synchronize multiple spin-transfer torque oscillators based on spin pumping, inverse spin Hall, and spin Hall effects. The proposed oscillator system consists of a series of nano-magnets in junction with a normal metal with high spin-orbit coupling, and an accumulative feedback loop. We conduct simulations to demonstrate the effect of modulated charge currents in the normal metal due to spin pumping from each nano-magnet. We show that the interplay between the spin Hall effect and inverse spin Hall effect results in synchronization of the nano-magnets.

Usefulness of esophagogastroduodenoscopy and 18F-fluorodeoxyglucose positron-emission tomography in detecting synchronous multiple primary cancers with oral cancer.

PubMed

Ishibashi-Kanno, Naomi; Yamagata, Kenji; Uchida, Fumihiko; Hasegawa, Shogo; Yanagawa, Toru; Bukawa, Hiroki

2017-12-01

The purpose of this study is to compare the value of screening for synchronous multiple primary cancers in other organs by esophagogastroduodenoscopy (EGD) or 18 F-fluorodeoxyglucose positron-emission tomography (PET-CT) in patients newly diagnosed with oral cancer. We retrospectively examined consecutive Japanese patients who were diagnosed with oral squamous cell carcinoma (OSCC) and were screened for synchronous multiple primary cancers in other organs by EGD and/or PET-CT between January 2010 and December 2015 at our institution. The study included 190 patients (106 males and 84 females) from 36 to 93 years of age (median age 68.8 years). The patients were screened by EGD, PET-CT, or both before beginning treatment for OSCC. Of 190 Japanese patients with OSCC, 15 had multiple primary cancers: 13 patients had double cancer and two had triple cancers. The sites of the 17 multiple primary cancers were gastric (6), esophageal (4), and lung (3), and ovarian, colon, liver, and thyroid (1 each). All of the gastric and esophageal cancers were found by EGD and were not detected by PET-CT. For three patients, the detection of multiple cancers affected the treatment modality or order of treatment selected for the OSCC. In two cases, the oral cancer and multiple primary cancer(s) in another organ were resected simultaneously by joint surgical teams. PET-CT for oral cancer patients is an effective supporting diagnostic tool. However, the ability of PET-CT has some limitations. Especially for early detection of the upper gastrointestinal cancers, it is necessary to be supplemented by EGD.

Fast concurrent array-based stacks, queues and deques using fetch-and-increment-bounded, fetch-and-decrement-bounded and store-on-twin synchronization primitives

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Dong; Gara, Alana; Heidelberger, Philip

Implementation primitives for concurrent array-based stacks, queues, double-ended queues (deques) and wrapped deques are provided. In one aspect, each element of the stack, queue, deque or wrapped deque data structure has its own ticket lock, allowing multiple threads to concurrently use multiple elements of the data structure and thus achieving high performance. In another aspect, new synchronization primitives FetchAndIncrementBounded (Counter, Bound) and FetchAndDecrementBounded (Counter, Bound) are implemented. These primitives can be implemented in hardware and thus promise a very fast throughput for queues, stacks and double-ended queues.

Peer Observation, Feedback and Reflection for Development of Practice in Synchronous Online Teaching

ERIC Educational Resources Information Center

Jones, Mark H.; Gallen, Anne-Marie

2016-01-01

Peer observation of teaching is an established developmental tool in face-to-face settings. While there have been studies into peer observation as applied to asynchronous online teaching, less is known about its application to teaching online using synchronous communication systems. We describe a small-scale study of an online peer observation…

Neural-adaptive control of single-master-multiple-slaves teleoperation for coordinated multiple mobile manipulators with time-varying communication delays and input uncertainties.

PubMed

Li, Zhijun; Su, Chun-Yi

2013-09-01

In this paper, adaptive neural network control is investigated for single-master-multiple-slaves teleoperation in consideration of time delays and input dead-zone uncertainties for multiple mobile manipulators carrying a common object in a cooperative manner. Firstly, concise dynamics of teleoperation systems consisting of a single master robot, multiple coordinated slave robots, and the object are developed in the task space. To handle asymmetric time-varying delays in communication channels and unknown asymmetric input dead zones, the nonlinear dynamics of the teleoperation system are transformed into two subsystems through feedback linearization: local master or slave dynamics including the unknown input dead zones and delayed dynamics for the purpose of synchronization. Then, a model reference neural network control strategy based on linear matrix inequalities (LMI) and adaptive techniques is proposed. The developed control approach ensures that the defined tracking errors converge to zero whereas the coordination internal force errors remain bounded and can be made arbitrarily small. Throughout this paper, stability analysis is performed via explicit Lyapunov techniques under specific LMI conditions. The proposed adaptive neural network control scheme is robust against motion disturbances, parametric uncertainties, time-varying delays, and input dead zones, which is validated by simulation studies.

Conformist-contrarian interactions and amplitude dependence in the Kuramoto model

NASA Astrophysics Data System (ADS)

Lohe, M. A.

2014-11-01

We derive exact formulas for the frequency of synchronized oscillations in Kuramoto models with conformist-contrarian interactions, and determine necessary conditions for synchronization to occur. Numerical computations show that for certain parameters repulsive nodes behave as conformists, and that in other cases attractive nodes can display frustration, being neither conformist nor contrarian. The signs of repulsive couplings can be placed equivalently outside the sum, as proposed in Hong and Strogatz (2011 Phys. Rev. Lett. 106 054102), or inside the sum as in Hong and Strogatz (2012 Phys. Rev. E 85 056210), but the two models have different characteristics for small magnitudes of the coupling constants. In the latter case we show that the distributed coupling constants can be viewed as oscillator amplitudes which are constant in time, with the property that oscillators of small amplitude couple only weakly to connected nodes. Such models provide a means of investigating the effect of amplitude variations on synchronization properties.

FPGA implementation of motifs-based neuronal network and synchronization analysis

NASA Astrophysics Data System (ADS)

Deng, Bin; Zhu, Zechen; Yang, Shuangming; Wei, Xile; Wang, Jiang; Yu, Haitao

2016-06-01

Motifs in complex networks play a crucial role in determining the brain functions. In this paper, 13 kinds of motifs are implemented with Field Programmable Gate Array (FPGA) to investigate the relationships between the networks properties and motifs properties. We use discretization method and pipelined architecture to construct various motifs with Hindmarsh-Rose (HR) neuron as the node model. We also build a small-world network based on these motifs and conduct the synchronization analysis of motifs as well as the constructed network. We find that the synchronization properties of motif determine that of motif-based small-world network, which demonstrates effectiveness of our proposed hardware simulation platform. By imitation of some vital nuclei in the brain to generate normal discharges, our proposed FPGA-based artificial neuronal networks have the potential to replace the injured nuclei to complete the brain function in the treatment of Parkinson's disease and epilepsy.

Control strategies of 3-cell Central Pattern Generator via global stimuli

NASA Astrophysics Data System (ADS)

Lozano, Álvaro; Rodríguez, Marcos; Barrio, Roberto

2016-03-01

The study of the synchronization patterns of small neuron networks that control several biological processes has become an interesting growing discipline. Some of these synchronization patterns of individual neurons are related to some undesirable neurological diseases, and they are believed to play a crucial role in the emergence of pathological rhythmic brain activity in different diseases, like Parkinson’s disease. We show how, with a suitable combination of short and weak global inhibitory and excitatory stimuli over the whole network, we can switch between different stable bursting patterns in small neuron networks (in our case a 3-neuron network). We develop a systematic study showing and explaining the effects of applying the pulses at different moments. Moreover, we compare the technique on a completely symmetric network and on a slightly perturbed one (a much more realistic situation). The present approach of using global stimuli may allow to avoid undesirable synchronization patterns with nonaggressive stimuli.

The linear synchronization measures of uterine EMG signals: Evidence of synchronized action potentials during propagation.

PubMed

Domino, Malgorzata; Pawlinski, Bartosz; Gajewski, Zdzislaw

2016-11-01

Evaluation of synchronization between myoelectric signals can give new insights into the functioning of the complex system of porcine myometrium. We propose a model of uterine contractions according to the hypothesis of action potentials similarity which is possible to detect during propagation in the uterine wall. We introduce similarity measures based on the concept of synchronization as used in matching linear signals such as electromyographic (EMG) time series data. The aim was to present linear measures to assess synchronization between contractions in different topographic regions of the uterus. We use the cross-correlation function (ƒx,y[l], ƒy,z[l]) and the cross-coherence function (Cxy[ƒ], Cyz[ƒ]) to assess synchronization between three data series of a diestral uterine EMG bundles in porcine reproductive tract. Spontaneous uterine activity was recorded using telemetry method directly by three-channel transmitter and three silver bipolar needle electrodes sutured on different topographic regions of the reproductive tract in the sow. The results show the usefulness of the cross-coherence function in that synchronization between uterine horn and corpus uteri for multiple action potentials (bundles) could be observed. The EMG bundles synchronization may be used to investigate the direction and velocity of EMG signals propagation in porcine reproductive tract. Copyright © 2016 Elsevier Inc. All rights reserved.

Files synchronization from a large number of insertions and deletions

NASA Astrophysics Data System (ADS)

Ellappan, Vijayan; Kumari, Savera

2017-11-01

Synchronization between different versions of files is becoming a major issue that most of the applications are facing. To make the applications more efficient a economical algorithm is developed from the previously used algorithm of “File Loading Algorithm”. I am extending this algorithm in three ways: First, dealing with non-binary files, Second backup is generated for uploaded files and lastly each files are synchronized with insertions and deletions. User can reconstruct file from the former file with minimizing the error and also provides interactive communication by eliminating the frequency without any disturbance. The drawback of previous system is overcome by using synchronization, in which multiple copies of each file/record is created and stored in backup database and is efficiently restored in case of any unwanted deletion or loss of data. That is, to introduce a protocol that user B may use to reconstruct file X from file Y with suitably low probability of error. Synchronization algorithms find numerous areas of use, including data storage, file sharing, source code control systems, and cloud applications. For example, cloud storage services such as Drop box synchronize between local copies and cloud backups each time users make changes to local versions. Similarly, synchronization tools are necessary in mobile devices. Specialized synchronization algorithms are used for video and sound editing. Synchronization tools are also capable of performing data duplication.

Predator-induced synchrony in population oscillations of coexisting small mammal species

PubMed Central

Korpimäki, Erkki; Norrdahl, Kai; Huitu, Otso; Klemola, Tero

2005-01-01

Comprehensive analyses of long-term (1977–2003) small-mammal abundance data from western Finland showed that populations of Microtus voles (field voles M. agrestis and sibling voles M. rossiaemeridionalis) voles, bank (Clethrionomys glareolus) and common shrews (Sorex araneus) fluctuated synchronously in 3 year population cycles. Time-series analyses indicated that interspecific synchrony is influenced strongly by density-dependent processes. Synchrony among Microtus and bank voles appeared additionally to be influenced by density-independent processes. To test whether interspecific synchronization through density-dependent processes is caused by predation, we experimentally reduced the densities of the main predators of small mammals in four large agricultural areas, and compared small mammal abundances in these to those in four control areas (2.5–3 km2) through a 3 year small-mammal population cycle. Predator reduction increased densities of the main prey species, Microtus voles, in all phases of the population cycle, while bank voles, the most important alternative prey of predators, responded positively only in the low and the increase phase. Manipulation also increased the autumn densities of water voles (Arvicola terrestris) in the increase phase of the cycle. No treatment effects were detected for common shrews or mice. Our results are in accordance with the alternative prey hypothesis, by which predators successively reduce the densities of both main and alternative prey species after the peak phase of small-mammal population cycles, thus inducing a synchronous low phase. PMID:15695211

Multichannel Detrended Fluctuation Analysis Reveals Synchronized Patterns of Spontaneous Spinal Activity in Anesthetized Cats

PubMed Central

Rodríguez, Erika E.; Hernández-Lemus, Enrique; Itzá-Ortiz, Benjamín A.; Jiménez, Ismael; Rudomín, Pablo

2011-01-01

The analysis of the interaction and synchronization of relatively large ensembles of neurons is fundamental for the understanding of complex functions of the nervous system. It is known that the temporal synchronization of neural ensembles is involved in the generation of specific motor, sensory or cognitive processes. Also, the intersegmental coherence of spinal spontaneous activity may indicate the existence of synaptic neural pathways between different pairs of lumbar segments. In this study we present a multichannel version of the detrended fluctuation analysis method (mDFA) to analyze the correlation dynamics of spontaneous spinal activity (SSA) from time series analysis. This method together with the classical detrended fluctuation analysis (DFA) were used to find out whether the SSA recorded in one or several segments in the spinal cord of the anesthetized cat occurs either in a random or in an organized manner. Our results are consistent with a non-random organization of the sets of neurons involved in the generation of spontaneous cord dorsum potentials (CDPs) recorded either from one lumbar segment (DFA- mean = 1.040.09) or simultaneously from several lumbar segments (mDFA- mean = 1.010.06), where  = 0.5 indicates randomness while 0.5 indicates long-term correlations. To test the sensitivity of the mDFA method we also examined the effects of small spinal lesions aimed to partially interrupt connectivity between neighboring lumbosacral segments. We found that the synchronization and correlation between the CDPs recorded from the L5 and L6 segments in both sides of the spinal cord were reduced when a lesion comprising the left dorsal quadrant was performed between the segments L5 and L6 (mDFA- = 0.992 as compared to initial conditions mDFA- = 1.186). The synchronization and correlation were reduced even further after a similar additional right spinal lesion (mDFA- = 0.924). In contrast to the classical methods, such as correlation and coherence quantification that define a relation between two sets of data, the mDFA method properly reveals the synchronization of multiple groups of neurons in several segments of the spinal cord. This method is envisaged as a useful tool to characterize the structure of higher order ensembles of cord dorsum spontaneous potentials after spinal cord or peripheral nerve lesions. PMID:22046288

Data-Gathering Scheme Using AUVs in Large-Scale Underwater Sensor Networks: A Multihop Approach

PubMed Central

Khan, Jawaad Ullah; Cho, Ho-Shin

2016-01-01

In this paper, we propose a data-gathering scheme for hierarchical underwater sensor networks, where multiple Autonomous Underwater Vehicles (AUVs) are deployed over large-scale coverage areas. The deployed AUVs constitute an intermittently connected multihop network through inter-AUV synchronization (in this paper, synchronization means an interconnection between nodes for communication) for forwarding data to the designated sink. In such a scenario, the performance of the multihop communication depends upon the synchronization among the vehicles. The mobility parameters of the vehicles vary continuously because of the constantly changing underwater currents. The variations in the AUV mobility parameters reduce the inter-AUV synchronization frequency contributing to delays in the multihop communication. The proposed scheme improves the AUV synchronization frequency by permitting neighboring AUVs to share their status information via a pre-selected node called an agent-node at the static layer of the network. We evaluate the proposed scheme in terms of the AUV synchronization frequency, vertical delay (node→AUV), horizontal delay (AUV→AUV), end-to-end delay, and the packet loss ratio. Simulation results show that the proposed scheme significantly reduces the aforementioned delays without the synchronization time-out process employed in conventional works. PMID:27706042

Data-Gathering Scheme Using AUVs in Large-Scale Underwater Sensor Networks: A Multihop Approach.

PubMed

Khan, Jawaad Ullah; Cho, Ho-Shin

2016-09-30

In this paper, we propose a data-gathering scheme for hierarchical underwater sensor networks, where multiple Autonomous Underwater Vehicles (AUVs) are deployed over large-scale coverage areas. The deployed AUVs constitute an intermittently connected multihop network through inter-AUV synchronization (in this paper, synchronization means an interconnection between nodes for communication) for forwarding data to the designated sink. In such a scenario, the performance of the multihop communication depends upon the synchronization among the vehicles. The mobility parameters of the vehicles vary continuously because of the constantly changing underwater currents. The variations in the AUV mobility parameters reduce the inter-AUV synchronization frequency contributing to delays in the multihop communication. The proposed scheme improves the AUV synchronization frequency by permitting neighboring AUVs to share their status information via a pre-selected node called an agent-node at the static layer of the network. We evaluate the proposed scheme in terms of the AUV synchronization frequency, vertical delay (node→AUV), horizontal delay (AUV→AUV), end-to-end delay, and the packet loss ratio. Simulation results show that the proposed scheme significantly reduces the aforementioned delays without the synchronization time-out process employed in conventional works.

Directional Networking in GPS Denied Environments - Time Synchronization

DTIC Science & Technology

2016-03-14

RF-based measurements to synchronize time and measure node range.  Satellite Doppler: Using Doppler measurements from multiple satellites along...with satellite catalog data to determine time and position.  LTE : Use existing LTE base-stations for time and position.  Differential GPS: A...Opportunistic Signals: Opportunistically take advantage of existing RF signals (i.e., FM radio, DTV, LTE , etc.) transmitted from known locations

Small worlds in space: Synchronization, spatial and relational modularity

NASA Astrophysics Data System (ADS)

Brede, M.

2010-06-01

In this letter we investigate networks that have been optimized to realize a trade-off between enhanced synchronization and cost of wire to connect the nodes in space. Analyzing the evolved arrangement of nodes in space and their corresponding network topology, a class of small-world networks characterized by spatial and network modularity is found. More precisely, for low cost of wire optimal configurations are characterized by a division of nodes into two spatial groups with maximum distance from each other, whereas network modularity is low. For high cost of wire, the nodes organize into several distinct groups in space that correspond to network modules connected on a ring. In between, spatially and relationally modular small-world networks are found.

Application of Soft Computing in Coherent Communications Phase Synchronization

NASA Technical Reports Server (NTRS)

Drake, Jeffrey T.; Prasad, Nadipuram R.

2000-01-01

The use of soft computing techniques in coherent communications phase synchronization provides an alternative to analytical or hard computing methods. This paper discusses a novel use of Adaptive Neuro-Fuzzy Inference Systems (ANFIS) for phase synchronization in coherent communications systems utilizing Multiple Phase Shift Keying (MPSK) modulation. A brief overview of the M-PSK digital communications bandpass modulation technique is presented and it's requisite need for phase synchronization is discussed. We briefly describe the hybrid platform developed by Jang that incorporates fuzzy/neural structures namely the, Adaptive Neuro-Fuzzy Interference Systems (ANFIS). We then discuss application of ANFIS to phase estimation for M-PSK. The modeling of both explicit, and implicit phase estimation schemes for M-PSK symbols with unknown structure are discussed. Performance results from simulation of the above scheme is presented.

Experiments with synchronized sCMOS cameras

NASA Astrophysics Data System (ADS)

Steele, Iain A.; Jermak, Helen; Copperwheat, Chris M.; Smith, Robert J.; Poshyachinda, Saran; Soonthorntham, Boonrucksar

2016-07-01

Scientific-CMOS (sCMOS) cameras can combine low noise with high readout speeds and do not suffer the charge multiplication noise that effectively reduces the quantum efficiency of electron multiplying CCDs by a factor 2. As such they have strong potential in fast photometry and polarimetry instrumentation. In this paper we describe the results of laboratory experiments using a pair of commercial off the shelf sCMOS cameras based around a 4 transistor per pixel architecture. In particular using a both stable and a pulsed light sources we evaluate the timing precision that may be obtained when the cameras readouts are synchronized either in software or electronically. We find that software synchronization can introduce an error of 200-msec. With electronic synchronization any error is below the limit ( 50-msec) of our simple measurement technique.

Shuttle bit rate synchronizer. [signal to noise ratios and error analysis

NASA Technical Reports Server (NTRS)

Huey, D. C.; Fultz, G. L.

1974-01-01

A shuttle bit rate synchronizer brassboard unit was designed, fabricated, and tested, which meets or exceeds the contractual specifications. The bit rate synchronizer operates at signal-to-noise ratios (in a bit rate bandwidth) down to -5 dB while exhibiting less than 0.6 dB bit error rate degradation. The mean acquisition time was measured to be less than 2 seconds. The synchronizer is designed around a digital data transition tracking loop whose phase and data detectors are integrate-and-dump filters matched to the Manchester encoded bits specified. It meets the reliability (no adjustments or tweaking) and versatility (multiple bit rates) of the shuttle S-band communication system through an implementation which is all digital after the initial stage of analog AGC and A/D conversion.

Synchronous activity in cat visual cortex encodes collinear and cocircular contours.

PubMed

Samonds, Jason M; Zhou, Zhiyi; Bernard, Melanie R; Bonds, A B

2006-04-01

We explored how contour information in primary visual cortex might be embedded in the simultaneous activity of multiple cells recorded with a 100-electrode array. Synchronous activity in cat visual cortex was more selective and predictable in discriminating between drifting grating and concentric ring stimuli than changes in firing rate. Synchrony was found even between cells with wholly different orientation preferences when their receptive fields were circularly aligned, and membership in synchronous groups was orientation and curvature dependent. The existence of synchrony between cocircular cells reinforces its role as a general mechanism for contour integration and shape detection as predicted by association field concepts. Our data suggest that cortical synchrony results from common and synchronous input from earlier visual areas and that it could serve to shape extrastriate response selectivity.

Flagellar Synchronization Is a Simple Alternative to Cell Cycle Synchronization for Ciliary and Flagellar Studies

PubMed Central

Dutta, Soumita

2017-01-01

ABSTRACT The unicellular green alga Chlamydomonas reinhardtii is an ideal model organism for studies of ciliary function and assembly. In assays for biological and biochemical effects of various factors on flagellar structure and function, synchronous culture is advantageous for minimizing variability. Here, we have characterized a method in which 100% synchronization is achieved with respect to flagellar length but not with respect to the cell cycle. The method requires inducing flagellar regeneration by amputation of the entire cell population and limiting regeneration time. This results in a maximally homogeneous distribution of flagellar lengths at 3 h postamputation. We found that time-limiting new protein synthesis during flagellar synchronization limits variability in the unassembled pool of limiting flagellar protein and variability in flagellar length without affecting the range of cell volumes. We also found that long- and short-flagella mutants that regenerate normally require longer and shorter synchronization times, respectively. By minimizing flagellar length variability using a simple method requiring only hours and no changes in media, flagellar synchronization facilitates the detection of small changes in flagellar length resulting from both chemical and genetic perturbations in Chlamydomonas. This method increases our ability to probe the basic biology of ciliary size regulation and related disease etiologies. IMPORTANCE Cilia and flagella are highly conserved antenna-like organelles that found in nearly all mammalian cell types. They perform sensory and motile functions contributing to numerous physiological and developmental processes. Defects in their assembly and function are implicated in a wide range of human diseases ranging from retinal degeneration to cancer. Chlamydomonas reinhardtii is an algal model system for studying mammalian cilium formation and function. Here, we report a simple synchronization method that allows detection of small changes in ciliary length by minimizing variability in the population. We find that this method alters the key relationship between cell size and the amount of protein accumulated for flagellar growth. This provides a rapid alternative to traditional methods of cell synchronization for uncovering novel regulators of cilia. PMID:28289724

Flagellar Synchronization Is a Simple Alternative to Cell Cycle Synchronization for Ciliary and Flagellar Studies.

PubMed

Dutta, Soumita; Avasthi, Prachee

2017-01-01

The unicellular green alga Chlamydomonas reinhardtii is an ideal model organism for studies of ciliary function and assembly. In assays for biological and biochemical effects of various factors on flagellar structure and function, synchronous culture is advantageous for minimizing variability. Here, we have characterized a method in which 100% synchronization is achieved with respect to flagellar length but not with respect to the cell cycle. The method requires inducing flagellar regeneration by amputation of the entire cell population and limiting regeneration time. This results in a maximally homogeneous distribution of flagellar lengths at 3 h postamputation. We found that time-limiting new protein synthesis during flagellar synchronization limits variability in the unassembled pool of limiting flagellar protein and variability in flagellar length without affecting the range of cell volumes. We also found that long- and short-flagella mutants that regenerate normally require longer and shorter synchronization times, respectively. By minimizing flagellar length variability using a simple method requiring only hours and no changes in media, flagellar synchronization facilitates the detection of small changes in flagellar length resulting from both chemical and genetic perturbations in Chlamydomonas . This method increases our ability to probe the basic biology of ciliary size regulation and related disease etiologies. IMPORTANCE Cilia and flagella are highly conserved antenna-like organelles that found in nearly all mammalian cell types. They perform sensory and motile functions contributing to numerous physiological and developmental processes. Defects in their assembly and function are implicated in a wide range of human diseases ranging from retinal degeneration to cancer. Chlamydomonas reinhardtii is an algal model system for studying mammalian cilium formation and function. Here, we report a simple synchronization method that allows detection of small changes in ciliary length by minimizing variability in the population. We find that this method alters the key relationship between cell size and the amount of protein accumulated for flagellar growth. This provides a rapid alternative to traditional methods of cell synchronization for uncovering novel regulators of cilia.

Exploration of bounded motion near binary systems comprised of small irregular bodies

NASA Astrophysics Data System (ADS)

Chappaz, Loic; Howell, Kathleen C.

2015-10-01

To investigate the behavior of a spacecraft near a pair of irregular bodies, consider a three-body configuration (one massless). Two massive bodies, P_1 and P_2, form the primary system; each primary is modeled as a sphere or an ellipsoid. Two primary configurations are addressed: `synchronous' and `non-synchronous'. Concepts and tools similar to those applied in the circular restricted three-body problem are exploited to construct periodic trajectories for a third body in synchronous systems. In non-synchronous systems, however, the search for third body periodic orbits is complicated by several factors. The mathematical model for the third-body motion is now time-variant and the motion of P_2 is not trivial.

Synchronization and bidirectional communication without delay line using strong mutually coupled semiconductor lasers

NASA Astrophysics Data System (ADS)

Li, Guang-Hui; Wang, An-Bang; Feng, Ye; Wang, Yang

2010-07-01

This paper numerically demonstrates synchronization and bidirectional communication without delay line by using two semiconductor lasers with strong mutual injection in a face-to-face configuration. These results show that both of the two lasers' outputs synchronize with their input chaotic carriers. In addition, simulations demonstrate that this kind of synchronization can be used to realize bidirectional communications without delay line. Further studies indicate that within a small deviation in message amplitudes of two sides (±6%), the message can be extracted with signal-noise-ratio more than 10 dB; and the signal-noise-ratio is extremely sensitive to the message rates mismatch of two sides, which may be used as a key of bidirectional communication.

Insensitivity of synchronization to network structure in chaotic pendulum systems with time-delay coupling.

PubMed

Yao, Chenggui; Zhan, Meng; Shuai, Jianwei; Ma, Jun; Kurths, Jürgen

2017-12-01

It has been generally believed that both time delay and network structure could play a crucial role in determining collective dynamical behaviors in complex systems. In this work, we study the influence of coupling strength, time delay, and network topology on synchronization behavior in delay-coupled networks of chaotic pendulums. Interestingly, we find that the threshold value of the coupling strength for complete synchronization in such networks strongly depends on the time delay in the coupling, but appears to be insensitive to the network structure. This lack of sensitivity was numerically tested in several typical regular networks, such as different locally and globally coupled ones as well as in several complex networks, such as small-world and scale-free networks. Furthermore, we find that the emergence of a synchronous periodic state induced by time delay is of key importance for the complete synchronization.

Using Hamiltonian control to desynchronize Kuramoto oscillators

NASA Astrophysics Data System (ADS)

Gjata, Oltiana; Asllani, Malbor; Barletti, Luigi; Carletti, Timoteo

2017-02-01

Many coordination phenomena are based on a synchronization process, whose global behavior emerges from the interactions among the individual parts. Often in nature, such self-organized mechanism allows the system to behave as a whole and thus grounding its very first existence, or expected functioning, on such process. There are, however, cases where synchronization acts against the stability of the system; for instance in some neurodegenerative diseases or epilepsy or the famous case of Millennium Bridge where the crowd synchronization of the pedestrians seriously endangered the stability of the structure. In this paper we propose an innovative control method to tackle the synchronization process based on the application of the Hamiltonian control theory, by adding a small control term to the system we are able to impede the onset of the synchronization. We present our results on a generalized class of the paradigmatic Kuramoto model.

Receptors as a master key for synchronization of rhythms

NASA Astrophysics Data System (ADS)

Nagano, Seido

2004-03-01

A simple, but general scheme to achieve synchronization of rhythms was derived. The scheme has been inductively generalized from the modelling study of cellular slime mold. It was clarified that biological receptors work as apparatuses that can convert external stimulus to the form of nonlinear interaction within individual oscillators. Namely, the mathematical model receptor works as a nonlinear coupling apparatus between nonlinear oscillators. Thus, synchronization is achieved as a result of competition between two kinds of non-linearities, and to achieve synchronization, even a small external stimulation via model receptors can change the characteristics of individual oscillators significantly. The derived scheme is very simple mathematically, but it is a very powerful scheme as numerically demonstrated. The biological receptor scheme should significantly help understanding of synchronization phenomena in biology since groups of limit cycle oscillators and receptors are ubiquitous in biological systems. Reference: S. Nagano, Phys Rev. E67, 056215(2003)

Method for traceable measurement of LTE signals

NASA Astrophysics Data System (ADS)

Sunder Dash, Soumya; Pythoud, Frederic; Leuchtmann, Pascal; Leuthold, Juerg

2018-04-01

This contribution presents a reference setup to measure the power of the cell-specific resource elements present in downlink long term evolution (LTE) signals in a way that the measurements are traceable to the international system of units. This setup can be used to calibrate the LTE code-selective field probes that are used to measure the radiation of base stations for mobile telephony. It can also be used to calibrate LTE signal generators and receivers. The method is based on traceable scope measurements performed directly at the output of a measuring antenna. It implements offline digital signal processing demodulation algorithms that consider the digital down-conversion, timing synchronization, frequency synchronization, phase synchronization and robust LTE cell identification to produce the downlink time-frequency LTE grid. Experimental results on conducted test scenarios, both single-input-single-output and multiple-input-multiple-output antenna configuration, show promising results confirming measurement uncertainties of the order of 0.05 dB with a coverage factor of 2.

Electrical Hyperexcitation of Lateral Ventral Pacemaker Neurons Desynchronizes Downstream Circadian Oscillators in the Fly Circadian Circuit and Induces Multiple Behavioral Periods

PubMed Central

Nitabach, Michael N.; Wu, Ying; Sheeba, Vasu; Lemon, William C.; Strumbos, John; Zelensky, Paul K.; White, Benjamin H.; Holmes, Todd C.

2008-01-01

Coupling of autonomous cellular oscillators is an essential aspect of circadian clock function but little is known about its circuit requirements. Functional ablation of the pigment-dispersing factor-expressing lateral ventral subset (LNV ) of Drosophila clock neurons abolishes circadian rhythms of locomotor activity. The hypothesis that LNVs synchronize oscillations in downstream clock neurons was tested by rendering the LNVs hyperexcitable via transgenic expression of a low activation threshold voltage-gated sodium channel. When the LNVs are made hyperexcitable, free-running behavioral rhythms decompose into multiple independent superimposed oscillations and the clock protein oscillations in the dorsal neuron 1 and 2 subgroups of clock neurons are phase-shifted. Thus, regulated electrical activity of the LNVs synchronize multiple oscillators in the fly circadian pacemaker circuit. PMID:16407545

Synchronous Spike Patterns in Macaque Motor Cortex during an Instructed-Delay Reach-to-Grasp Task

PubMed Central

Torre, Emiliano; Quaglio, Pietro; Denker, Michael; Brochier, Thomas; Riehle, Alexa

2016-01-01

The computational role of spike time synchronization at millisecond precision among neurons in the cerebral cortex is hotly debated. Studies performed on data of limited size provided experimental evidence that low-order correlations occur in relation to behavior. Advances in electrophysiological technology to record from hundreds of neurons simultaneously provide the opportunity to observe coordinated spiking activity of larger populations of cells. We recently published a method that combines data mining and statistical evaluation to search for significant patterns of synchronous spikes in massively parallel spike trains (Torre et al., 2013). The method solves the computational and multiple testing problems raised by the high dimensionality of the data. In the current study, we used our method on simultaneous recordings from two macaque monkeys engaged in an instructed-delay reach-to-grasp task to determine the emergence of spike synchronization in relation to behavior. We found a multitude of synchronous spike patterns aligned in both monkeys along a preferential mediolateral orientation in brain space. The occurrence of the patterns is highly specific to behavior, indicating that different behaviors are associated with the synchronization of different groups of neurons (“cell assemblies”). However, pooled patterns that overlap in neuronal composition exhibit no specificity, suggesting that exclusive cell assemblies become active during different behaviors, but can recruit partly identical neurons. These findings are consistent across multiple recording sessions analyzed across the two monkeys. SIGNIFICANCE STATEMENT Neurons in the brain communicate via electrical impulses called spikes. How spikes are coordinated to process information is still largely unknown. Synchronous spikes are effective in triggering a spike emission in receiving neurons and have been shown to occur in relation to behavior in a number of studies on simultaneous recordings of few neurons. We recently published a method to extend this type of investigation to larger data. Here, we apply it to simultaneous recordings of hundreds of neurons from the motor cortex of macaque monkeys performing a motor task. Our analysis reveals groups of neurons selectively synchronizing their activity in relation to behavior, which sheds new light on the role of synchrony in information processing in the cerebral cortex. PMID:27511007

Synchronous Spike Patterns in Macaque Motor Cortex during an Instructed-Delay Reach-to-Grasp Task.

PubMed

Torre, Emiliano; Quaglio, Pietro; Denker, Michael; Brochier, Thomas; Riehle, Alexa; Grün, Sonja

2016-08-10

The computational role of spike time synchronization at millisecond precision among neurons in the cerebral cortex is hotly debated. Studies performed on data of limited size provided experimental evidence that low-order correlations occur in relation to behavior. Advances in electrophysiological technology to record from hundreds of neurons simultaneously provide the opportunity to observe coordinated spiking activity of larger populations of cells. We recently published a method that combines data mining and statistical evaluation to search for significant patterns of synchronous spikes in massively parallel spike trains (Torre et al., 2013). The method solves the computational and multiple testing problems raised by the high dimensionality of the data. In the current study, we used our method on simultaneous recordings from two macaque monkeys engaged in an instructed-delay reach-to-grasp task to determine the emergence of spike synchronization in relation to behavior. We found a multitude of synchronous spike patterns aligned in both monkeys along a preferential mediolateral orientation in brain space. The occurrence of the patterns is highly specific to behavior, indicating that different behaviors are associated with the synchronization of different groups of neurons ("cell assemblies"). However, pooled patterns that overlap in neuronal composition exhibit no specificity, suggesting that exclusive cell assemblies become active during different behaviors, but can recruit partly identical neurons. These findings are consistent across multiple recording sessions analyzed across the two monkeys. Neurons in the brain communicate via electrical impulses called spikes. How spikes are coordinated to process information is still largely unknown. Synchronous spikes are effective in triggering a spike emission in receiving neurons and have been shown to occur in relation to behavior in a number of studies on simultaneous recordings of few neurons. We recently published a method to extend this type of investigation to larger data. Here, we apply it to simultaneous recordings of hundreds of neurons from the motor cortex of macaque monkeys performing a motor task. Our analysis reveals groups of neurons selectively synchronizing their activity in relation to behavior, which sheds new light on the role of synchrony in information processing in the cerebral cortex. Copyright © 2016 Torre, et al.

Dynamical noise filter and conditional entropy analysis in chaos synchronization.

PubMed

Wang, Jiao; Lai, C-H

2006-06-01

It is shown that, in a chaotic synchronization system whose driving signal is exposed to channel noise, the estimation of the drive system states can be greatly improved by applying the dynamical noise filtering to the response system states. If the noise is bounded in a certain range, the estimation errors, i.e., the difference between the filtered responding states and the driving states, can be made arbitrarily small. This property can be used in designing an alternative digital communication scheme. An analysis based on the conditional entropy justifies the application of dynamical noise filtering in generating quality synchronization.

Synchronization and coordination of sequences in two neural ensembles

NASA Astrophysics Data System (ADS)

Venaille, Antoine; Varona, Pablo; Rabinovich, Mikhail I.

2005-06-01

There are many types of neural networks involved in the sequential motor behavior of animals. For high species, the control and coordination of the network dynamics is a function of the higher levels of the central nervous system, in particular the cerebellum. However, in many cases, especially for invertebrates, such coordination is the result of direct synaptic connections between small circuits. We show here that even the chaotic sequential activity of small model networks can be coordinated by electrotonic synapses connecting one or several pairs of neurons that belong to two different networks. As an example, we analyzed the coordination and synchronization of the sequential activity of two statocyst model networks of the marine mollusk Clione. The statocysts are gravity sensory organs that play a key role in postural control of the animal and the generation of a complex hunting motor program. Each statocyst network was modeled by a small ensemble of neurons with Lotka-Volterra type dynamics and nonsymmetric inhibitory interactions. We studied how two such networks were synchronized by electrical coupling in the presence of an external signal which lead to winnerless competition among the neurons. We found that as a function of the number and the strength of connections between the two networks, it is possible to coordinate and synchronize the sequences that each network generates with its own chaotic dynamics. In spite of the chaoticity, the coordination of the signals is established through an activation sequence lock for those neurons that are active at a particular instant of time.

Synchronization of three electrochemical oscillators: From local to global coupling

NASA Astrophysics Data System (ADS)

Liu, Yifan; Sebek, Michael; Mori, Fumito; Kiss, István Z.

2018-04-01

We investigate the formation of synchronization patterns in an oscillatory nickel electrodissolution system in a network obtained by superimposing local and global coupling with three electrodes. We explored the behavior through numerical simulations using kinetic ordinary differential equations, Kuramoto type phase models, and experiments, in which the local to global coupling could be tuned by cross resistances between the three nickel wires. At intermediate coupling strength with predominant global coupling, two of the three oscillators, whose natural frequencies are closer, can synchronize. By adding even a relatively small amount of local coupling (about 9%-25%), a spatially organized partially synchronized state can occur where one of the two synchronized elements is in the center. A formula was derived for predicting the critical coupling strength at which full synchronization will occur independent of the permutation of the natural frequencies of the oscillators over the network. The formula correctly predicts the variation of the critical coupling strength as a function of the global coupling fraction, e.g., with local coupling the critical coupling strength is about twice than that required with global coupling. The results show the importance of the topology of the network on the synchronization properties in a simple three-oscillator setup and could provide guidelines for decrypting coupling topology from identification of synchronization patterns.

Multiple video sequences synchronization during minimally invasive surgery

NASA Astrophysics Data System (ADS)

Belhaoua, Abdelkrim; Moreau, Johan; Krebs, Alexandre; Waechter, Julien; Radoux, Jean-Pierre; Marescaux, Jacques

2016-03-01

Hybrid operating rooms are an important development in the medical ecosystem. They allow integrating, in the same procedure, the advantages of radiological imaging and surgical tools. However, one of the challenges faced by clinical engineers is to support the connectivity and interoperability of medical-electrical point-of-care devices. A system that could enable plug-and-play connectivity and interoperability for medical devices would improve patient safety, save hospitals time and money, and provide data for electronic medical records. In this paper, we propose a hardware platform dedicated to collect and synchronize multiple videos captured from medical equipment in real-time. The final objective is to integrate augmented reality technology into an operation room (OR) in order to assist the surgeon during a minimally invasive operation. To the best of our knowledge, there is no prior work dealing with hardware based video synchronization for augmented reality applications on OR. Whilst hardware synchronization methods can embed temporal value, so called timestamp, into each sequence on-the-y and require no post-processing, they require specialized hardware. However the design of our hardware is simple and generic. This approach was adopted and implemented in this work and its performance is evaluated by comparison to the start-of-the-art methods.

Early multisensory interactions affect the competition among multiple visual objects.

PubMed

Van der Burg, Erik; Talsma, Durk; Olivers, Christian N L; Hickey, Clayton; Theeuwes, Jan

2011-04-01

In dynamic cluttered environments, audition and vision may benefit from each other in determining what deserves further attention and what does not. We investigated the underlying neural mechanisms responsible for attentional guidance by audiovisual stimuli in such an environment. Event-related potentials (ERPs) were measured during visual search through dynamic displays consisting of line elements that randomly changed orientation. Search accuracy improved when a target orientation change was synchronized with an auditory signal as compared to when the auditory signal was absent or synchronized with a distractor orientation change. The ERP data show that behavioral benefits were related to an early multisensory interaction over left parieto-occipital cortex (50-60 ms post-stimulus onset), which was followed by an early positive modulation (80-100 ms) over occipital and temporal areas contralateral to the audiovisual event, an enhanced N2pc (210-250 ms), and a contralateral negative slow wave (CNSW). The early multisensory interaction was correlated with behavioral search benefits, indicating that participants with a strong multisensory interaction benefited the most from the synchronized auditory signal. We suggest that an auditory signal enhances the neural response to a synchronized visual event, which increases the chances of selection in a multiple object environment. Copyright © 2010 Elsevier Inc. All rights reserved.

Robustness of cluster synchronous patterns in small-world networks with inter-cluster co-competition balance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Jianbao; Ma, Zhongjun, E-mail: mzj1234402@163.com; Chen, Guanrong

All edges in the classical Watts and Strogatz's small-world network model are unweighted and cooperative (positive). By introducing competitive (negative) inter-cluster edges and assigning edge weights to mimic more realistic networks, this paper develops a modified model which possesses co-competitive weighted couplings and cluster structures while maintaining the common small-world network properties of small average shortest path lengths and large clustering coefficients. Based on theoretical analysis, it is proved that the new model with inter-cluster co-competition balance has an important dynamical property of robust cluster synchronous pattern formation. More precisely, clusters will neither merge nor split regardless of adding ormore » deleting nodes and edges, under the condition of inter-cluster co-competition balance. Numerical simulations demonstrate the robustness of the model against the increase of the coupling strength and several topological variations.« less

Robustness of cluster synchronous patterns in small-world networks with inter-cluster co-competition balance

NASA Astrophysics Data System (ADS)

Zhang, Jianbao; Ma, Zhongjun; Chen, Guanrong

2014-06-01

All edges in the classical Watts and Strogatz's small-world network model are unweighted and cooperative (positive). By introducing competitive (negative) inter-cluster edges and assigning edge weights to mimic more realistic networks, this paper develops a modified model which possesses co-competitive weighted couplings and cluster structures while maintaining the common small-world network properties of small average shortest path lengths and large clustering coefficients. Based on theoretical analysis, it is proved that the new model with inter-cluster co-competition balance has an important dynamical property of robust cluster synchronous pattern formation. More precisely, clusters will neither merge nor split regardless of adding or deleting nodes and edges, under the condition of inter-cluster co-competition balance. Numerical simulations demonstrate the robustness of the model against the increase of the coupling strength and several topological variations.

Web-Based Architecture to Enable Compute-Intensive CAD Tools and Multi-user Synchronization in Teleradiology

NASA Astrophysics Data System (ADS)

Mehta, Neville; Kompalli, Suryaprakash; Chaudhary, Vipin

Teleradiology is the electronic transmission of radiological patient images, such as x-rays, CT, or MR across multiple locations. The goal could be interpretation, consultation, or medical records keeping. Information technology solutions have enabled electronic records and their associated benefits are evident in health care today. However, salient aspects of collaborative interfaces, and computer assisted diagnostic (CAD) tools are yet to be integrated into workflow designs. The Computer Assisted Diagnostics and Interventions (CADI) group at the University at Buffalo has developed an architecture that facilitates web-enabled use of CAD tools, along with the novel concept of synchronized collaboration. The architecture can support multiple teleradiology applications and case studies are presented here.

NULL Convention Floating Point Multiplier

PubMed Central

Ramachandran, Seshasayanan

2015-01-01

Floating point multiplication is a critical part in high dynamic range and computational intensive digital signal processing applications which require high precision and low power. This paper presents the design of an IEEE 754 single precision floating point multiplier using asynchronous NULL convention logic paradigm. Rounding has not been implemented to suit high precision applications. The novelty of the research is that it is the first ever NULL convention logic multiplier, designed to perform floating point multiplication. The proposed multiplier offers substantial decrease in power consumption when compared with its synchronous version. Performance attributes of the NULL convention logic floating point multiplier, obtained from Xilinx simulation and Cadence, are compared with its equivalent synchronous implementation. PMID:25879069

NULL convention floating point multiplier.

PubMed

Albert, Anitha Juliette; Ramachandran, Seshasayanan

2015-01-01

Floating point multiplication is a critical part in high dynamic range and computational intensive digital signal processing applications which require high precision and low power. This paper presents the design of an IEEE 754 single precision floating point multiplier using asynchronous NULL convention logic paradigm. Rounding has not been implemented to suit high precision applications. The novelty of the research is that it is the first ever NULL convention logic multiplier, designed to perform floating point multiplication. The proposed multiplier offers substantial decrease in power consumption when compared with its synchronous version. Performance attributes of the NULL convention logic floating point multiplier, obtained from Xilinx simulation and Cadence, are compared with its equivalent synchronous implementation.

Different EGFR gene mutations in two patients with synchronous multiple lung cancers: A case report

PubMed Central

Sakai, Hiroki; Kimura, Hiroyuki; Tsuda, Masataka; Wakiyama, Yoichi; Miyazawa, Tomoyuki; Marushima, Hideki; Kojima, Koji; Hoshikawa, Masahiro; Takagi, Masayuki; Nakamura, Haruhiko

2017-01-01

Routine clinical and pathological evaluations to determine the relationship between different lesions are often not completely conclusive. Interestingly, detailed genetic analysis of tumor samples may provide important additional information and identify second primary lung cancers. In the present study, we report cases of two synchronous lung adenocarcinomas composed of two distinct pathological subtypes with different EGFR gene mutations: a homozygous deletion in exon 19 of the papillary adenocarcinoma subtype and a point mutation of L858R in exon 21 of the tubular adenocarcinoma. The present report highlights the clinical importance of molecular cancer biomarkers to guide management decisions in cases involving multiple lung tumors. PMID:29090842

Development of sub-100 femtosecond timing and synchronization system

NASA Astrophysics Data System (ADS)

Lin, Zhenyang; Du, Yingchao; Yang, Jin; Xu, Yilun; Yan, Lixin; Huang, Wenhui; Tang, Chuanxiang; Huang, Gang; Du, Qiang; Doolittle, Lawrence; Wilcox, Russell; Byrd, John

2018-01-01

The precise timing and synchronization system is an essential part for the ultra-fast electron and X-ray sources based on the photocathode injector where strict synchronization among RF, laser, and beams are required. In this paper, we present an integrated sub-100 femtosecond timing and synchronization system developed and demonstrated recently in Tsinghua University based on the collaboration with Lawrence Berkeley National Lab. The timing and synchronization system includes the fiber-based CW carrier phase reference distribution system for delivering stabilized RF phase reference to multiple receiver clients, the Low Level RF (LLRF) control system to monitor and generate the phase and amplitude controllable pulse RF signal, and the laser-RF synchronization system for high precision synchronization between optical and RF signals. Each subsystem is characterized by its blocking structure and is also expansible. A novel asymmetric calibration sideband signal method was proposed for eliminating the non-linear distortion in the optical synchronization process. According to offline and online tests, the system can deliver a stable signal to each client and suppress the drift and jitter of the RF signal for the accelerator and the laser oscillator to less than 100 fs RMS (˜0.1° in 2856 MHz frequency). Moreover, a demo system with a LLRF client and a laser-RF synchronization client is deployed and operated successfully at the Tsinghua Thomson scattering X-ray source. The beam-based jitter measurement experiments have been conducted to evaluate the overall performance of the system, and the jitter sources are discussed.

Development of sub-100 femtosecond timing and synchronization system.

PubMed

Lin, Zhenyang; Du, Yingchao; Yang, Jin; Xu, Yilun; Yan, Lixin; Huang, Wenhui; Tang, Chuanxiang; Huang, Gang; Du, Qiang; Doolittle, Lawrence; Wilcox, Russell; Byrd, John

2018-01-01

The precise timing and synchronization system is an essential part for the ultra-fast electron and X-ray sources based on the photocathode injector where strict synchronization among RF, laser, and beams are required. In this paper, we present an integrated sub-100 femtosecond timing and synchronization system developed and demonstrated recently in Tsinghua University based on the collaboration with Lawrence Berkeley National Lab. The timing and synchronization system includes the fiber-based CW carrier phase reference distribution system for delivering stabilized RF phase reference to multiple receiver clients, the Low Level RF (LLRF) control system to monitor and generate the phase and amplitude controllable pulse RF signal, and the laser-RF synchronization system for high precision synchronization between optical and RF signals. Each subsystem is characterized by its blocking structure and is also expansible. A novel asymmetric calibration sideband signal method was proposed for eliminating the non-linear distortion in the optical synchronization process. According to offline and online tests, the system can deliver a stable signal to each client and suppress the drift and jitter of the RF signal for the accelerator and the laser oscillator to less than 100 fs RMS (∼0.1° in 2856 MHz frequency). Moreover, a demo system with a LLRF client and a laser-RF synchronization client is deployed and operated successfully at the Tsinghua Thomson scattering X-ray source. The beam-based jitter measurement experiments have been conducted to evaluate the overall performance of the system, and the jitter sources are discussed.

An inter-networking mechanism with stepwise synchronization for wireless sensor networks.

PubMed

Yamamoto, Hiroshi; Wakamiya, Naoki; Murata, Masayuki

2011-01-01

To realize the ambient information society, multiple wireless networks deployed in the region and devices carried by users are required to cooperate with each other. Since duty cycles and operational frequencies are different among networks, we need a mechanism to allow networks to efficiently exchange messages. For this purpose, we propose a novel inter-networking mechanism where two networks are synchronized with each other in a moderate manner, which we call stepwise synchronization. With our proposal, to bridge the gap between intrinsic operational frequencies, nodes near the border of networks adjust their operational frequencies in a stepwise fashion based on the pulse-coupled oscillator model as a fundamental theory of synchronization. Through simulation experiments, we show that the communication delay and the energy consumption of border nodes are reduced, which enables wireless sensor networks to communicate longer with each other.

On the impact index of synchronous generator displaced by DFIG on power system small-signal stability

NASA Astrophysics Data System (ADS)

Bi, J. T.; Du, W. J.; Wang, H. F.; Song, Y. T.; Wang, Q.; Ding, J.; Chen, D. Z.; Wei, W.

2017-05-01

As the maturity of wind power technology and the ageing and retirement of conventional synchronous generators, the displacement of synchronous generators by wind power generators would be a trend in the next few decades. The power system small-signal angular stability caused by the displacement is an urgent problem to be studied. The displacement of the SG by the DFIG includes withdrawing the dynamic interactions of the displaced SG and adding the dynamic interactions of the displacing DFIG. Based on this fact, a new index is proposed to predict the impact of the SG to be displaced by the DFIG on power system oscillation modes. The sensitivity index of the oscillation modes to the constant inertia of the displaced SGs, proposed in early literatures to estimate the dynamic impact of the SG being displaced by the DFIG, is also compared with the proposed index. The modified New England power system is adopted to show various results and conclusions. The proposed index can correctly identify the most dangerous and beneficial displacement to power system small-signal angular stability, and is very useful in practical applications.

Phase synchronization of bursting neurons in clustered small-world networks

NASA Astrophysics Data System (ADS)

Batista, C. A. S.; Lameu, E. L.; Batista, A. M.; Lopes, S. R.; Pereira, T.; Zamora-López, G.; Kurths, J.; Viana, R. L.

2012-07-01

We investigate the collective dynamics of bursting neurons on clustered networks. The clustered network model is composed of subnetworks, each of them presenting the so-called small-world property. This model can also be regarded as a network of networks. In each subnetwork a neuron is connected to other ones with regular as well as random connections, the latter with a given intracluster probability. Moreover, in a given subnetwork each neuron has an intercluster probability to be connected to the other subnetworks. The local neuron dynamics has two time scales (fast and slow) and is modeled by a two-dimensional map. In such small-world network the neuron parameters are chosen to be slightly different such that, if the coupling strength is large enough, there may be synchronization of the bursting (slow) activity. We give bounds for the critical coupling strength to obtain global burst synchronization in terms of the network structure, that is, the probabilities of intracluster and intercluster connections. We find that, as the heterogeneity in the network is reduced, the network global synchronizability is improved. We show that the transitions to global synchrony may be abrupt or smooth depending on the intercluster probability.

Heterogeneity and nearest-neighbor coupling can explain small-worldness and wave properties in pancreatic islets

NASA Astrophysics Data System (ADS)

Cappon, Giacomo; Pedersen, Morten Gram

2016-05-01

Many multicellular systems consist of coupled cells that work as a syncytium. The pancreatic islet of Langerhans is a well-studied example of such a microorgan. The islets are responsible for secretion of glucose-regulating hormones, mainly glucagon and insulin, which are released in distinct pulses. In order to observe pulsatile insulin secretion from the β-cells within the islets, the cellular responses must be synchronized. It is now well established that gap junctions provide the electrical nearest-neighbor coupling that allows excitation waves to spread across islets to synchronize the β-cell population. Surprisingly, functional coupling analysis of calcium responses in β-cells shows small-world properties, i.e., a high degree of local coupling with a few long-range "short-cut" connections that reduce the average path-length greatly. Here, we investigate how such long-range functional coupling can appear as a result of heterogeneity, nearest-neighbor coupling, and wave propagation. Heterogeneity is also able to explain a set of experimentally observed synchronization and wave properties without introducing all-or-none cell coupling and percolation theory. Our theoretical results highlight how local biological coupling can give rise to functional small-world properties via heterogeneity and wave propagation.

Disturbed resting state EEG synchronization in bipolar disorder: A graph-theoretic analysis☆

PubMed Central

Kim, Dae-Jin; Bolbecker, Amanda R.; Howell, Josselyn; Rass, Olga; Sporns, Olaf; Hetrick, William P.; Breier, Alan; O'Donnell, Brian F.

2013-01-01

Disruption of functional connectivity may be a key feature of bipolar disorder (BD) which reflects disturbances of synchronization and oscillations within brain networks. We investigated whether the resting electroencephalogram (EEG) in patients with BD showed altered synchronization or network properties. Resting-state EEG was recorded in 57 BD type-I patients and 87 healthy control subjects. Functional connectivity between pairs of EEG channels was measured using synchronization likelihood (SL) for 5 frequency bands (δ, θ, α, β, and γ). Graph-theoretic analysis was applied to SL over the electrode array to assess network properties. BD patients showed a decrease of mean synchronization in the alpha band, and the decreases were greatest in fronto-central and centro-parietal connections. In addition, the clustering coefficient and global efficiency were decreased in BD patients, whereas the characteristic path length increased. We also found that the normalized characteristic path length and small-worldness were significantly correlated with depression scores in BD patients. These results suggest that BD patients show impaired neural synchronization at rest and a disruption of resting-state functional connectivity. PMID:24179795

Emergent gamma synchrony in all-to-all interneuronal networks.

PubMed

Ratnadurai-Giridharan, Shivakeshavan; Khargonekar, Pramod P; Talathi, Sachin S

2015-01-01

We investigate the emergence of in-phase synchronization in a heterogeneous network of coupled inhibitory interneurons in the presence of spike timing dependent plasticity (STDP). Using a simple network of two mutually coupled interneurons (2-MCI), we first study the effects of STDP on in-phase synchronization. We demonstrate that, with STDP, the 2-MCI network can evolve to either a state of stable 1:1 in-phase synchronization or exhibit multiple regimes of higher order synchronization states. We show that the emergence of synchronization induces a structural asymmetry in the 2-MCI network such that the synapses onto the high frequency firing neurons are potentiated, while those onto the low frequency firing neurons are de-potentiated, resulting in the directed flow of information from low frequency firing neurons to high frequency firing neurons. Finally, we demonstrate that the principal findings from our analysis of the 2-MCI network contribute to the emergence of robust synchronization in the Wang-Buzsaki network (Wang and Buzsáki, 1996) of all-to-all coupled inhibitory interneurons (100-MCI) for a significantly larger range of heterogeneity in the intrinsic firing rate of the neurons in the network. We conclude that STDP of inhibitory synapses provide a viable mechanism for robust neural synchronization.

Emergent gamma synchrony in all-to-all interneuronal networks

PubMed Central

Ratnadurai-Giridharan, Shivakeshavan; Khargonekar, Pramod P.; Talathi, Sachin S.

2015-01-01

We investigate the emergence of in-phase synchronization in a heterogeneous network of coupled inhibitory interneurons in the presence of spike timing dependent plasticity (STDP). Using a simple network of two mutually coupled interneurons (2-MCI), we first study the effects of STDP on in-phase synchronization. We demonstrate that, with STDP, the 2-MCI network can evolve to either a state of stable 1:1 in-phase synchronization or exhibit multiple regimes of higher order synchronization states. We show that the emergence of synchronization induces a structural asymmetry in the 2-MCI network such that the synapses onto the high frequency firing neurons are potentiated, while those onto the low frequency firing neurons are de-potentiated, resulting in the directed flow of information from low frequency firing neurons to high frequency firing neurons. Finally, we demonstrate that the principal findings from our analysis of the 2-MCI network contribute to the emergence of robust synchronization in the Wang-Buzsaki network (Wang and Buzsáki, 1996) of all-to-all coupled inhibitory interneurons (100-MCI) for a significantly larger range of heterogeneity in the intrinsic firing rate of the neurons in the network. We conclude that STDP of inhibitory synapses provide a viable mechanism for robust neural synchronization. PMID:26528174

Estimation of accuracy of time synchronization obtained by means of clock transportation

NASA Astrophysics Data System (ADS)

Zhang, Yuzhen; Ma, Dekang; Jin, Wenjing; Zhao, Gang; Huang, Peicheng

A portable clock experiment was carried out in October 1985 between Shanghai Observatory and Beijing Observatory using a small quartz clock made in Switzerland. The accuracy of time synchronization in 5 days is 70.18 microsec and the accuracy of determining the transmission time of short wave is satisfactory for reduction of the astronomical observations to the same master clock.

Emergence of ultrafast sparsely synchronized rhythms and their responses to external stimuli in an inhomogeneous small-world complex neuronal network.

PubMed

Kim, Sang-Yoon; Lim, Woochang

2017-09-01

We consider an inhomogeneous small-world network (SWN) composed of inhibitory short-range (SR) and long-range (LR) interneurons, and investigate the effect of network architecture on emergence of synchronized brain rhythms by varying the fraction of LR interneurons p long . The betweenness centralities of the LR and SR interneurons (characterizing the potentiality in controlling communication between other interneurons) are distinctly different. Hence, in view of the betweenness, SWNs we consider are inhomogeneous, unlike the "canonical" Watts-Strogatz SWN with nearly the same betweenness centralities. For small p long , the load of communication traffic is much concentrated on a few LR interneurons. However, as p long is increased, the number of LR connections (coming from LR interneurons) increases, and then the load of communication traffic is less concentrated on LR interneurons, which leads to better efficiency of global communication between interneurons. Sparsely synchronized rhythms are thus found to emerge when passing a small critical value p long (c) (≃0.16). The population frequency of the sparsely synchronized rhythm is ultrafast (higher than 100 Hz), while the mean firing rate of individual interneurons is much lower (∼30 Hz) due to stochastic and intermittent neural discharges. These dynamical behaviors in the inhomogeneous SWN are also compared with those in the homogeneous Watts-Strogatz SWN, in connection with their network topologies. Particularly, we note that the main difference between the two types of SWNs lies in the distribution of betweenness centralities. Unlike the case of the Watts-Strogatz SWN, dynamical responses to external stimuli vary depending on the type of stimulated interneurons in the inhomogeneous SWN. We consider two cases of external time-periodic stimuli applied to sub-populations of the LR and SR interneurons, respectively. Dynamical responses (such as synchronization suppression and enhancement) to these two cases of stimuli are studied and discussed in relation to the betweenness centralities of stimulated interneurons, representing the effectiveness for transfer of stimulation effect in the whole network. Copyright © 2017 Elsevier Ltd. All rights reserved.

Analysis of Trends and Factors in Breast Multiple Primary Malignant Neoplasms

PubMed Central

Motuzyuk, Igor; Sydorchuk, Oleg; Kovtun, Natalia; Palian, Zinaida; Kostiuchenko, Yevhenii

2018-01-01

Background: The study aims to evaluate the current state and tendencies in multiple primary breast cancer incidence, behavior, and treatment in Ukraine. Methods: A total of 2032 patients who received special treatment at the Department of Breast Tumors and Reconstructive Surgery of the National Cancer Institute from 2008 to 2015 were included in the study. Among them, there were 195 patients with multiple primary malignant neoplasms: 54.9% patients with synchronous cancer and 45.1% patients with metachronous cancer. The average age of patients was 46.6 years, and the percentage of postmenopausal women was 63.1%. Among patients with synchronous cancer, there were 56.1% patients with only breast localizations and 43.9% with combination of breast and other localizations, and among patients with metachronous cancer, there were 46.6% patients with only breast localizations and 53.4% with combination of breast and other localizations. All the patients were evaluated in terms of aggressiveness of the disease, survival rates, as well as risk factors and treatment options. Results: A more aggressive course of breast cancer is observed in patients exposed to radiation from the Chernobyl accident under the age of 30 years (P < .01). The clinical course of disease in patients with synchronous cancer is worse and prognostically unfavorable compared with metachronous cancer (P < .01). The course of the disease in patients who underwent mastectomy is worse compared with patients who underwent breast-conserving surgery (P < .01). Plastic and reconstructive surgery in patients with synchronous cancer was proven to be reasonable in terms of increase in survival (P < .01). Conclusions: The patients with multiple primary breast cancer should have attentive management and treatment. Multidisciplinary team should concern all the risk factors and provide the most sufficient option of management. This is crucial to continue research in this oncological area. PMID:29531473

Interface Message Processors for the ARPA Computer Network

DTIC Science & Technology

1976-07-01

and then clear the location) as its primitive locking facility (i.e., as the necessary multiprocessor lock equivalent to Dijkstra semaphores )[37]. To...of the extra storage required for the redundant copies. There is the problem of maintaining synchronization of multiple copy data bases in the presence...through any of the data base sites. I Update synchronization . Races between conflicting, "concurrent" update requests are resolved in a manner that j

Genuine Quantum Signatures in Synchronization of Anharmonic Self-Oscillators.

PubMed

Lörch, Niels; Amitai, Ehud; Nunnenkamp, Andreas; Bruder, Christoph

2016-08-12

We study the synchronization of a Van der Pol self-oscillator with Kerr anharmonicity to an external drive. We demonstrate that the anharmonic, discrete energy spectrum of the quantum oscillator leads to multiple resonances in both phase locking and frequency entrainment not present in the corresponding classical system. Strong driving close to these resonances leads to nonclassical steady-state Wigner distributions. Experimental realizations of these genuine quantum signatures can be implemented with current technology.

ROSA: Distributed Joint Routing and Dynamic Spectrum Allocation in Cognitive Radio Ad Hoc Networks

DTIC Science & Technology

2010-03-01

Aug. 1999. [20] I. N. Psaromiligkos and S. N. Batalama. Rapid Combined Synchronization/Demodulation Structures for DS - CDMA Systems - Part II: Finite...Medley. Rapid Combined Synchronization/Demodulation Structures for DS - CDMA Systems - Part I: Algorithmic developments. IEEE Transactions on...multiple access ( CDMA ) [21][20] al- low concurrent co-located communications so that a message from node i to node j can be correctly received even if

Synchronous male breast and colon cancer presenting with ileus: A case report.

PubMed

Ari, Aziz; Tatar, Cihad; Buyukasik, Kenan; Segmen, Ozgur; Cakir, Coskun; Arikan, Soykan

2016-01-01

Cancer developing from more than one origin is called multiple primary cancer (MPC) and is a rare situation. In this article, we report a case presenting to the Emergency Clinic with symptoms of ileus who was diagnosed with synchronous colon and breast cancer. A 57year old male patient presented to the Emergency Clinic with abdominal pain, vomiting, constipation and lack of flatulence. The patient was taken to the operating room for emergency surgery with the diagnosis of intestinal obstruction. While still hospitalized, breast ultrasound was performed, revealing a mass lesion in the right breast measuring 2cm. The core biopsy result was suggestive of invasive ductal adenocarcinoma. Right modified radical mastectomy with removal of the level 2 axillary lymph nodes was performed. The result of the histopathological investigation of the right hemicolectomy specimen was reported as moderately differentiated adenocarcinoma, while that of the mastectomy material was invasive ductal adenocarcinoma. Synchronous colorectal cancer is recognized as an important clinical entity, its clinical and pathological properties as well as prognosis are still undetermined. A family history of cancer might be a significant factor in synchronous cancers. Many of the theories about the etiology of multiple primary malignant neoplasia suggest the role of genetic, hormonal, environmental and immunological factors as well as iatrogenic causes. Especially for patients whose treatment begins in the emergency settings, meticulous systemic physical examination is recommended to initiate treatment of a possible synchronous tumor at an earlier stage. Copyright © 2016 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Factors affecting synchronization and conception rate after the Ovsynch protocol in lactating Holstein cows.

PubMed

Galvão, K N; Santos, J E P

2010-06-01

Objectives were to evaluate risk factors affecting ovulatory responses and conception rate to the Ovsynch protocol. Holstein cows, 466, were submitted to the Ovsynch protocol [day 0, GnRH-1; day 7, prostaglandin (PG) F(2alpha); day 9, GnRH-2] and 103 cows were inseminated 12 h after GnRH-2. Information on parity, days in milk at GnRH-1, body condition, milk yield, exposure to heat stress, pre-synchronization with PGF(2alpha) and the use of progesterone insert from GnRH-1 to PGF(2alpha) was collected. Ovaries were scanned to determine responses to treatments. Overall, 54.7%, 10.6%, 2.2%, 81.1%, 9.0%, 91.5% and 36.9% of the cows ovulated to GnRH-1, multiple ovulated to GnRH-1, ovulated before GnRH-2, ovulated to GnRH-2, multiple ovulated to GnRH-2, experienced corpus luteum (CL) regression and conceived, respectively. Ovulation to GnRH-1 was greater in cows without a CL at GnRH-1, cows with follicles >19 mm and cows not pre-synchronized with PGF(2alpha) 14 days before GnRH-1. Multiple ovulations to GnRH-1 increased in cows without CL at GnRH-1 and cows with follicles < or =19 mm at GnRH-1. Ovulation before GnRH-2 was greater in cows without CL at PGF(2alpha). Ovulation to GnRH-2 increased in cows that received a progesterone insert, cows with a CL at GnRH-1, cows with follicles not regressing from the PGF(2alpha) to GnRH-2, cows with larger follicles at GnRH-2, cows that ovulated to GnRH-1 and cows not pre-synchronized. Multiple ovulations after GnRH-2 increased in cows with no CL at GnRH-1, multiparous cows and cows that multiple ovulated to GnRH-1. Conception rate at 42 days after AI increased in cows with body condition score > 2.75 and cows that ovulated to GnRH-2. Strategies that optimize ovulation to GnRH-2, such as increased ovulation to GnRH-1, should improve response to the Ovsynch protocol.

A distributed transmit beamforming synchronization strategy for multi-element radar systems

NASA Astrophysics Data System (ADS)

Xiao, Manlin; Li, Xingwen; Xu, Jikang

2017-02-01

The distributed transmit beamforming has recently been discussed as an energy-effective technique in wireless communication systems. A common ground of various techniques is that the destination node transmits a beacon signal or feedback to assist source nodes to synchronize signals. However, this approach is not appropriate for a radar system since the destination is a non-cooperative target of an unknown location. In our paper, we propose a novel synchronization strategy for a distributed multiple-element beamfoming radar system. Source nodes estimate parameters of beacon signals transmitted from others to get their local synchronization information. The channel information of the phase propagation delay is transmitted to nodes via the reflected beacon signals as well. Next, each node generates appropriate parameters to form a beamforming signal at the target. Transmit beamforming signals of all nodes will combine coherently at the target compensating for different propagation delay. We analyse the influence of the local oscillation accuracy and the parameter estimation errors on the performance of the proposed synchronization scheme. The results of numerical simulations illustrate that this synchronization scheme is effective to enable the transmit beamforming in a distributed multi-element radar system.

Homomorphic Filtering for Improving Time Synchronization in Wireless Networks

PubMed Central

Castillo-Secilla, José María; Palomares, José Manuel; León, Fernando; Olivares, Joaquín

2017-01-01

Wireless sensor networks are used to sample the environment in a distributed way. Therefore, it is mandatory for all of the measurements to be tightly synchronized in order to guarantee that every sensor is sampling the environment at the exact same instant of time. The synchronization drift gets bigger in environments suffering from temperature variations. Thus, this work is focused on improving time synchronization under deployments with temperature variations. The working hypothesis demonstrated in this work is that the clock skew of two nodes (the ratio of the real frequencies of the oscillators) is composed of a multiplicative combination of two main components: the clock skew due to the variations between the cut of the crystal of each oscillator and the clock skew due to the different temperatures affecting the nodes. By applying a nonlinear filtering, the homomorphic filtering, both components are separated in an effective way. A correction factor based on temperature, which can be applied to any synchronization protocol, is proposed. For testing it, an improvement of the FTSP synchronization protocol has been developed and physically tested under temperature variation scenarios using TelosB motes flashed with the IEEE 802.15.4 implementation supplied by TinyOS. PMID:28425955

Homomorphic Filtering for Improving Time Synchronization in Wireless Networks.

PubMed

Castillo-Secilla, José María; Palomares, José Manuel; León, Fernando; Olivares, Joaquín

2017-04-20

Wireless sensor networks are used to sample the environment in a distributed way. Therefore, it is mandatory for all of the measurements to be tightly synchronized in order to guarantee that every sensor is sampling the environment at the exact same instant of time. The synchronization drift gets bigger in environments suffering from temperature variations. Thus, this work is focused on improving time synchronization under deployments with temperature variations. The working hypothesis demonstrated in this work is that the clock skew of two nodes (the ratio of the real frequencies of the oscillators) is composed of a multiplicative combination of two main components: the clock skew due to the variations between the cut of the crystal of each oscillator and the clock skew due to the different temperatures affecting the nodes. By applying a nonlinear filtering, the homomorphic filtering, both components are separated in an effective way. A correction factor based on temperature, which can be applied to any synchronization protocol, is proposed. For testing it, an improvement of the FTSP synchronization protocol has been developed and physically tested under temperature variation scenarios using TelosB motes flashed with the IEEE 802.15.4 implementation supplied by TinyOS.

Title: Chimeras in small, globally coupled networks: Experiments and stability analysis

NASA Astrophysics Data System (ADS)

Hart, Joseph D.; Bansal, Kanika; Murphy, Thomas E.; Roy, Rajarshi

Since the initial observation of chimera states, there has been much discussion of the conditions under which these states emerge. The emphasis thus far has mainly been to analyze large networks of coupled oscillators; however, recent studies have begun to focus on the opposite limit: what is the smallest system of coupled oscillators in which chimeras can exist? We experimentally observe chimeras and other partially synchronous patterns in a network of four globally-coupled chaotic opto-electronic oscillators. By examining the equations of motion, we demonstrate that symmetries in the network topology allow a variety of synchronous states to exist, including cluster synchronous states and a chimera state. Using the group theoretical approach recently developed for analyzing cluster synchronization, we show how to derive the variational equations for these synchronous patterns and calculate their linear stability. The stability analysis gives good agreement with our experimental results. Both experiments and simulations suggest that these chimera states often appear in regions of multistability between global, cluster, and desynchronized states.

Modular networks with delayed coupling: Synchronization and frequency control

NASA Astrophysics Data System (ADS)

Maslennikov, Oleg V.; Nekorkin, Vladimir I.

2014-07-01

We study the collective dynamics of modular networks consisting of map-based neurons which generate irregular spike sequences. Three types of intramodule topology are considered: a random Erdös-Rényi network, a small-world Watts-Strogatz network, and a scale-free Barabási-Albert network. The interaction between the neurons of different modules is organized by relatively sparse connections with time delay. For all the types of the network topology considered, we found that with increasing delay two regimes of module synchronization alternate with each other: inphase and antiphase. At the same time, the average rate of collective oscillations decreases within each of the time-delay intervals corresponding to a particular synchronization regime. A dual role of the time delay is thus established: controlling a synchronization mode and degree and controlling an average network frequency. Furthermore, we investigate the influence on the modular synchronization by other parameters: the strength of intermodule coupling and the individual firing rate.

Synchronization properties of heterogeneous neuronal networks with mixed excitability type

NASA Astrophysics Data System (ADS)

Leone, Michael J.; Schurter, Brandon N.; Letson, Benjamin; Booth, Victoria; Zochowski, Michal; Fink, Christian G.

2015-03-01

We study the synchronization of neuronal networks with dynamical heterogeneity, showing that network structures with the same propensity for synchronization (as quantified by master stability function analysis) may develop dramatically different synchronization properties when heterogeneity is introduced with respect to neuronal excitability type. Specifically, we investigate networks composed of neurons with different types of phase response curves (PRCs), which characterize how oscillating neurons respond to excitatory perturbations. Neurons exhibiting type 1 PRC respond exclusively with phase advances, while neurons exhibiting type 2 PRC respond with either phase delays or phase advances, depending on when the perturbation occurs. We find that Watts-Strogatz small world networks transition to synchronization gradually as the proportion of type 2 neurons increases, whereas scale-free networks may transition gradually or rapidly, depending upon local correlations between node degree and excitability type. Random placement of type 2 neurons results in gradual transition to synchronization, whereas placement of type 2 neurons as hubs leads to a much more rapid transition, showing that type 2 hub cells easily "hijack" neuronal networks to synchronization. These results underscore the fact that the degree of synchronization observed in neuronal networks is determined by a complex interplay between network structure and the dynamical properties of individual neurons, indicating that efforts to recover structural connectivity from dynamical correlations must in general take both factors into account.

An Inter-Networking Mechanism with Stepwise Synchronization for Wireless Sensor Networks

PubMed Central

Yamamoto, Hiroshi; Wakamiya, Naoki; Murata, Masayuki

2011-01-01

To realize the ambient information society, multiple wireless networks deployed in the region and devices carried by users are required to cooperate with each other. Since duty cycles and operational frequencies are different among networks, we need a mechanism to allow networks to efficiently exchange messages. For this purpose, we propose a novel inter-networking mechanism where two networks are synchronized with each other in a moderate manner, which we call stepwise synchronization. With our proposal, to bridge the gap between intrinsic operational frequencies, nodes near the border of networks adjust their operational frequencies in a stepwise fashion based on the pulse-coupled oscillator model as a fundamental theory of synchronization. Through simulation experiments, we show that the communication delay and the energy consumption of border nodes are reduced, which enables wireless sensor networks to communicate longer with each other. PMID:22164073

Array of Synchronized Nano-Oscillators Based on Repulsion between Domain Wall and Skyrmion

NASA Astrophysics Data System (ADS)

Jin, Chendong; Wang, Jianbo; Wang, Weiwei; Song, Chengkun; Wang, Jinshuai; Xia, Haiyan; Liu, Qingfang

2018-04-01

Spin-transfer nano-oscillators (STNOs) are nanosized microwave signal generators based on spin-transfer torque and the magnetoresistance effect. So far, the low output power of STNOs is one of the key restrictive factors. Fabrication and synchronization of a multiple STNO array in one device is a promising way to increase the output power. However, previous studies have shown that only a limited number of STNOs achieve synchronization due to the complex coupling mechanism. In this work, we propose an alternative structure of STNOs based on the repulsion between the domain wall and the Skyrmion. It is found that the frequency tunability of this kind of STNO reaches up to 1.9 GHz. Moreover, we numerically demonstrate that the integrated arrays of STNOs can export synchronous signals, which is promising to potentially increase their total power. Our results provide alternatives for designing of Skyrmion-based devices and further improving the output power of STNOs.

Subxiphoid uniportal video-assisted thoracoscopic surgery for synchronous bilateral lung resection.

PubMed

Yang, Xueying; Wang, Linlin

2018-01-01

With advancements in medical imaging and current emphasis on regular physical examinations, multiple pulmonary lesions increasingly are being detected, including bilateral pulmonary lesions. Video-assisted thoracic surgery is an important method for treating such lesions. Most of video-assisted thoracic surgeries for bilateral pulmonary lesions were two separate operations. Herein, we report a novel technique of synchronous subxiphoid uniportal video-assisted thoracic surgery for bilateral pulmonary lesions. Synchronous bilateral lung resection procedures were performed through a single incision (~4 cm, subxiphoid). This technique was used successfully in 11 patients with bilateral pulmonary lesions. There were no intraoperative deaths or mortality recorded at 30 days. Our results show that the subxiphoid uniportal thoracoscopic procedure is a safe and feasible surgical procedure for synchronous bilateral lung resection with less surgical trauma, postoperative pain and better cosmetic results in qualifying patients. Further analysis is ongoing, involving a larger number of subjects.

A CDMA synchronisation scheme

NASA Technical Reports Server (NTRS)

Soprano, C.

1993-01-01

CDMA (Code Division Multiple Access) is known to decrease inter-service interference in Satellite Communication Systems. Its performance is increased by chip quasi-synchronous operation which virtually eliminates the self-noise; however, the theory shows that the time error on the synchronization has to be kept at less than one tenth of a chip which, for 1 Mchip/sec. spreading rate, corresponds to 10(exp -7) sec. This, on the return-link, may only be achieved by means of a closed loop control system which, for mobile communication systems, has to be capable of autonomous operation. Until now some results have been reported on the feasibility of chip quasi-synchronous operation for mobile communication systems only including satellites on GEO (Geostationary Earth Orbit). In what follows, the basic principles are exposed, and results are presented showing how low chip synchronism error may be achieved by means of an autonomous control loop operating through satellites on any Earth orbit.

Time Synchronization and Distribution Mechanisms for Space Networks

NASA Technical Reports Server (NTRS)

Woo, Simon S.; Gao, Jay L.; Clare, Loren P.; Mills, David L.

2011-01-01

This work discusses research on the problems of synchronizing and distributing time information between spacecraft based on the Network Time Protocol (NTP), where NTP is a standard time synchronization protocol widely used in the terrestrial network. The Proximity-1 Space Link Interleaved Time Synchronization (PITS) Protocol was designed and developed for synchronizing spacecraft that are in proximity where proximity is less than 100,000 km distant. A particular application is synchronization between a Mars orbiter and rover. Lunar scenarios as well as outer-planet deep space mother-ship-probe missions may also apply. Spacecraft with more accurate time information functions as a time-server, and the other spacecraft functions as a time-client. PITS can be easily integrated and adaptable to the CCSDS Proximity-1 Space Link Protocol with minor modifications. In particular, PITS can take advantage of the timestamping strategy that underlying link layer functionality provides for accurate time offset calculation. The PITS algorithm achieves time synchronization with eight consecutive space network time packet exchanges between two spacecraft. PITS can detect and avoid possible errors from receiving duplicate and out-of-order packets by comparing with the current state variables and timestamps. Further, PITS is able to detect error events and autonomously recover from unexpected events that can possibly occur during the time synchronization and distribution process. This capability achieves an additional level of protocol protection on top of CRC or Error Correction Codes. PITS is a lightweight and efficient protocol, eliminating the needs for explicit frame sequence number and long buffer storage. The PITS protocol is capable of providing time synchronization and distribution services for a more general domain where multiple entities need to achieve time synchronization using a single point-to-point link.

Visual capture and the experience of having two bodies – Evidence from two different virtual reality techniques

PubMed Central

Heydrich, Lukas; Dodds, Trevor J.; Aspell, Jane E.; Herbelin, Bruno; Bülthoff, Heinrich H.; Mohler, Betty J.; Blanke, Olaf

2013-01-01

In neurology and psychiatry the detailed study of illusory own body perceptions has suggested close links between bodily processing and self-consciousness. One such illusory own body perception is heautoscopy where patients have the sensation of being reduplicated and to exist at two or even more locations. In previous experiments, using a video head-mounted display, self-location and self-identification were manipulated by applying conflicting visuo-tactile information. Yet the experienced singularity of the self was not affected, i.e., participants did not experience having multiple bodies or selves. In two experiments presented in this paper, we investigated self-location and self-identification while participants saw two virtual bodies (video-generated in study 1 and 3D computer generated in study 2) that were stroked either synchronously or asynchronously with their own body. In both experiments, we report that self-identification with two virtual bodies was stronger during synchronous stroking. Furthermore, in the video generated setup with synchronous stroking participants reported a greater feeling of having multiple bodies than in the control conditions. In study 1, but not in study 2, we report that self-location – measured by anterior posterior drift – was significantly shifted towards the two bodies in the synchronous condition only. Self-identification with two bodies, the sensation of having multiple bodies, and the changes in self-location show that the experienced singularity of the self can be studied experimentally. We discuss our data with respect to ownership for supernumerary hands and heautoscopy. We finally compare the effects of the video and 3D computer generated head-mounted display technology and discuss the possible benefits of using either technology to induce changes in illusory self-identification with a virtual body. PMID:24385970

Synchronization as Aggregation: Cluster Kinetics of Pulse-Coupled Oscillators.

PubMed

O'Keeffe, Kevin P; Krapivsky, P L; Strogatz, Steven H

2015-08-07

We consider models of identical pulse-coupled oscillators with global interactions. Previous work showed that under certain conditions such systems always end up in sync, but did not quantify how small clusters of synchronized oscillators progressively coalesce into larger ones. Using tools from the study of aggregation phenomena, we obtain exact results for the time-dependent distribution of cluster sizes as the system evolves from disorder to synchrony.

Synchronization for Optical PPM Signals

NASA Technical Reports Server (NTRS)

Vilnrotter, V. A.

1985-01-01

Method based on statistical properties of weak pulse-positionmodulated (PPM) signal enables synchronization of receiver clock with received-signal time base. Method applies to weak optical M-ary PPM signals, for which there is only one pulse of length Tp transmitted during one of timeslots of length T in each successive interval of M timeslots. Method requires small dead time, Td, at beginning and end of each timeslot, during which pulse amplitude is zero.

More Gamma More Predictions: Gamma-Synchronization as a Key Mechanism for Efficient Integration of Classical Receptive Field Inputs with Surround Predictions

PubMed Central

Vinck, Martin; Bosman, Conrado A.

2016-01-01

During visual stimulation, neurons in visual cortex often exhibit rhythmic and synchronous firing in the gamma-frequency (30–90 Hz) band. Whether this phenomenon plays a functional role during visual processing is not fully clear and remains heavily debated. In this article, we explore the function of gamma-synchronization in the context of predictive and efficient coding theories. These theories hold that sensory neurons utilize the statistical regularities in the natural world in order to improve the efficiency of the neural code, and to optimize the inference of the stimulus causes of the sensory data. In visual cortex, this relies on the integration of classical receptive field (CRF) data with predictions from the surround. Here we outline two main hypotheses about gamma-synchronization in visual cortex. First, we hypothesize that the precision of gamma-synchronization reflects the extent to which CRF data can be accurately predicted by the surround. Second, we hypothesize that different cortical columns synchronize to the extent that they accurately predict each other’s CRF visual input. We argue that these two hypotheses can account for a large number of empirical observations made on the stimulus dependencies of gamma-synchronization. Furthermore, we show that they are consistent with the known laminar dependencies of gamma-synchronization and the spatial profile of intercolumnar gamma-synchronization, as well as the dependence of gamma-synchronization on experience and development. Based on our two main hypotheses, we outline two additional hypotheses. First, we hypothesize that the precision of gamma-synchronization shows, in general, a negative dependence on RF size. In support, we review evidence showing that gamma-synchronization decreases in strength along the visual hierarchy, and tends to be more prominent in species with small V1 RFs. Second, we hypothesize that gamma-synchronized network dynamics facilitate the emergence of spiking output that is particularly information-rich and sparse. PMID:27199684

Stability analysis and synchronization in discrete-time complex networks with delayed coupling

NASA Astrophysics Data System (ADS)

Cheng, Ranran; Peng, Mingshu; Yu, Weibin; Sun, Bo; Yu, Jinchen

2013-12-01

A new network of coupled maps is proposed in which the connections between units involve no delays but the intra-neural communication does, whereas in the work of Atay et al. [Phys. Rev. Lett. 92, 144101 (2004)], the focus is on information processing delayed by the inter-neural communication. We show that the synchronization of the network depends on not only the intrinsic dynamical features and inter-connection topology (characterized by the spectrum of the graph Laplacian) but also the delays and the coupling strength. There are two main findings: (i) the more neighbours, the easier to be synchronized; (ii) odd delays are easier to be synchronized than even ones. In addition, compared with those discussed by Atay et al. [Phys. Rev. Lett. 92, 144101 (2004)], our model has a better synchronizability for regular networks and small-world variants.

Fraternal Twin Tumours of the Oesophagus and Stomach Presenting in the Advanced Stage - A Rare Case with a Fatal End.

PubMed

Sreeram, Saraswathy; Venkataramana, Chaithra Gowthuvalli; Kini, Jyoti Ramanath; Rao, Ranjitha; Murali, Nirupama

2017-04-01

Synchronous primary tumours of the aerodigestive tract presenting with different histologies is a very rare event. A case with such an association is presented here. A 50-year-old lady presented with symptoms of abdominal obstruction like abdominal pain, distention and vomiting since one month. Her radiological imaging and biopsies revealed a primary oesophageal squamous cell carcinoma and primary gastric adenocarcinoma. Western medical literature has shown the occurrence of multiple synchronous cancers; however, cases from India have seldom been reported. Early screening, correct diagnosis and appropriate plans of management are crucial to reduce the morbidity and mortality of such patients who bear the burden of not just one, but multiple primary cancers.

The Added Diagnostic Value of 18F-Fluorodihydroxyphenylalanine PET/CT in the Preoperative Work-Up of Small Bowel Neuroendocrine Tumors.

PubMed

Addeo, Pietro; Poncet, Gilles; Goichot, Bernard; Leclerc, Loic; Brigand, Cécile; Mutter, Didier; Romain, Benoit; Namer, Izzie-Jacques; Bachellier, Philippe; Imperiale, Alessio

2018-04-01

The precise localization of the primary tumor and/or the identification of multiple primary tumors improves the preoperative work-up in patients with small bowel (SB) neuroendocrine tumor (NET). The present study assesses the diagnostic value of 18 F-fluorodihydroxyphenylalanine ( 18 F-FDOPA) positron emission tomography/computed tomography (PET/CT) during the preoperative wok-up of SB NETs. Between January 2010 and June 2017, all consecutive patients with SB NETs undergoing preoperative 18 F-FDOPA PET/CT and successive resection were analyzed. Preoperative work-up included computed tomography (CT), somatostatin receptor scintigraphy (SRS), and 18 F-FDOPA PET/CT. Sensitivity and accuracy ratio for primary and multiple tumor detection were compared with data from surgery and pathology. There were 17 consecutive patients with SB NETs undergoing surgery. Nine patients (53%) had multiple tumors, 15 (88%) metastatic lymph nodes, 3 (18%) peritoneal carcinomatosis, and 9 patients (53%) liver metastases. A total of 70 SB NETs were found by pathology. Surgery identified the primary in 17/17 (100%) patients and recognized seven of 9 patients (78%) with multiple synchronous SB. Preoperatively, 18 F-FDOPA PET/CT displayed a statistically significant higher sensitivity for primary tumor localization (100 vs. 23.5 vs. 29.5%) and multiple tumor detection (78 vs. 22 vs. 11%) over SRS and CT. Compared with pathology, 18 F-FDOPA PET/CT displayed the highest accuracy ratio for number of tumor detected over CT and SRS (2.0 ± 2.2 vs. 0.4 ± 0.7 vs. 0.6 ± 1.5, p = 0.0003). 18 F-FDOPA PET/CT significantly increased the sensitivity and accuracy for primary and multiple SB NET identification. 18 F-FDOPA PET/CT should be included systematically in the preoperative work-up of SB NET.

Intra- and inter-brain synchronization during musical improvisation on the guitar.

PubMed

Müller, Viktor; Sänger, Johanna; Lindenberger, Ulman

2013-01-01

Humans interact with the environment through sensory and motor acts. Some of these interactions require synchronization among two or more individuals. Multiple-trial designs, which we have used in past work to study interbrain synchronization in the course of joint action, constrain the range of observable interactions. To overcome the limitations of multiple-trial designs, we conducted single-trial analyses of electroencephalography (EEG) signals recorded from eight pairs of guitarists engaged in musical improvisation. We identified hyper-brain networks based on a complex interplay of different frequencies. The intra-brain connections primarily involved higher frequencies (e.g., beta), whereas inter-brain connections primarily operated at lower frequencies (e.g., delta and theta). The topology of hyper-brain networks was frequency-dependent, with a tendency to become more regular at higher frequencies. We also found hyper-brain modules that included nodes (i.e., EEG electrodes) from both brains. Some of the observed network properties were related to musical roles during improvisation. Our findings replicate and extend earlier work and point to mechanisms that enable individuals to engage in temporally coordinated joint action.

Intra- and Inter-Brain Synchronization during Musical Improvisation on the Guitar

PubMed Central

Müller, Viktor; Sänger, Johanna; Lindenberger, Ulman

2013-01-01

Humans interact with the environment through sensory and motor acts. Some of these interactions require synchronization among two or more individuals. Multiple-trial designs, which we have used in past work to study interbrain synchronization in the course of joint action, constrain the range of observable interactions. To overcome the limitations of multiple-trial designs, we conducted single-trial analyses of electroencephalography (EEG) signals recorded from eight pairs of guitarists engaged in musical improvisation. We identified hyper-brain networks based on a complex interplay of different frequencies. The intra-brain connections primarily involved higher frequencies (e.g., beta), whereas inter-brain connections primarily operated at lower frequencies (e.g., delta and theta). The topology of hyper-brain networks was frequency-dependent, with a tendency to become more regular at higher frequencies. We also found hyper-brain modules that included nodes (i.e., EEG electrodes) from both brains. Some of the observed network properties were related to musical roles during improvisation. Our findings replicate and extend earlier work and point to mechanisms that enable individuals to engage in temporally coordinated joint action. PMID:24040094

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hayes, T.; Smith, K.S.; Severino, F.

A critical capability of the new RHIC low level rf (LLRF) system is the ability to synchronize signals across multiple locations. The 'Update Link' provides this functionality. The 'Update Link' is a deterministic serial data link based on the Xilinx RocketIO protocol that is broadcast over fiber optic cable at 1 gigabit per second (Gbps). The link provides timing events and data packets as well as time stamp information for synchronizing diagnostic data from multiple sources. The new RHIC LLRF was designed to be a flexible, modular system. The system is constructed of numerous independent RF Controller chassis. To providemore » synchronization among all of these chassis, the Update Link system was designed. The Update Link system provides a low latency, deterministic data path to broadcast information to all receivers in the system. The Update Link system is based on a central hub, the Update Link Master (ULM), which generates the data stream that is distributed via fiber optic links. Downstream chassis have non-deterministic connections back to the ULM that allow any chassis to provide data that is broadcast globally.« less

Inter-layer synchronization in non-identical multi-layer networks

NASA Astrophysics Data System (ADS)

Leyva, I.; Sevilla-Escoboza, R.; Sendiña-Nadal, I.; Gutiérrez, R.; Buldú, J. M.; Boccaletti, S.

2017-04-01

Inter-layer synchronization is a dynamical process occurring in multi-layer networks composed of identical nodes. This process emerges when all layers are synchronized, while nodes in each layer do not necessarily evolve in unison. So far, the study of such inter-layer synchronization has been restricted to the case in which all layers have an identical connectivity structure. When layers are not identical, the inter-layer synchronous state is no longer a stable solution of the system. Nevertheless, when layers differ in just a few links, an approximate treatment is still feasible, and allows one to gather information on whether and how the system may wander around an inter-layer synchronous configuration. We report the details of an approximate analytical treatment for a two-layer multiplex, which results in the introduction of an extra inertial term accounting for structural differences. Numerical validation of the predictions highlights the usefulness of our approach, especially for small or moderate topological differences in the intra-layer coupling. Moreover, we identify a non-trivial relationship connecting the betweenness centrality of the missing links and the intra-layer coupling strength. Finally, by the use of multiplexed layers of electronic circuits, we study the inter-layer synchronization as a function of the removed links.

Chimeralike states in two distinct groups of identical populations of coupled Stuart-Landau oscillators

NASA Astrophysics Data System (ADS)

Premalatha, K.; Chandrasekar, V. K.; Senthilvelan, M.; Lakshmanan, M.

2017-02-01

We show the existence of chimeralike states in two distinct groups of identical populations of globally coupled Stuart-Landau oscillators. The existence of chimeralike states occurs only for a small range of frequency difference between the two populations, and these states disappear for an increase of mismatch between the frequencies. Here the chimeralike states are characterized by the synchronized oscillations in one population and desynchronized oscillations in another population. We also find that such states observed in two distinct groups of identical populations of nonlocally coupled oscillators are different from the above case in which coexisting domains of synchronized and desynchronized oscillations are observed in one population and the second population exhibits synchronized oscillations for spatially prepared initial conditions. Perturbation from such spatially prepared initial condition leads to the existence of imperfectly synchronized states. An imperfectly synchronized state represents the existence of solitary oscillators which escape from the synchronized group in population I and synchronized oscillations in population II. Also the existence of chimera state is independent of the increase of frequency mismatch between the populations. We also find the coexistence of different dynamical states with respect to different initial conditions, which causes multistability in the globally coupled system. In the case of nonlocal coupling, the system does not show multistability except in the cluster state region.

Sensorimotor Synchronization with Different Metrical Levels of Point-Light Dance Movements.

PubMed

Su, Yi-Huang

2016-01-01

Rhythm perception and synchronization have been extensively investigated in the auditory domain, as they underlie means of human communication such as music and speech. Although recent studies suggest comparable mechanisms for synchronizing with periodically moving visual objects, the extent to which it applies to ecologically relevant information, such as the rhythm of complex biological motion, remains unknown. The present study addressed this issue by linking rhythm of music and dance in the framework of action-perception coupling. As a previous study showed that observers perceived multiple metrical periodicities in dance movements that embodied this structure, the present study examined whether sensorimotor synchronization (SMS) to dance movements resembles what is known of auditory SMS. Participants watched a point-light figure performing two basic steps of Swing dance cyclically, in which the trunk bounced at every beat and the limbs moved at every second beat, forming two metrical periodicities. Participants tapped synchronously to the bounce of the trunk with or without the limbs moving in the stimuli (Experiment 1), or tapped synchronously to the leg movements with or without the trunk bouncing simultaneously (Experiment 2). Results showed that, while synchronization with the bounce (lower-level pulse) was not influenced by the presence or absence of limb movements (metrical accent), synchronization with the legs (beat) was improved by the presence of the bounce (metrical subdivision) across different movement types. The latter finding parallels the "subdivision benefit" often demonstrated in auditory tasks, suggesting common sensorimotor mechanisms for visual rhythms in dance and auditory rhythms in music.

Effects of nuclear electromagnetic pulse (EMP) on synchronous stability of the electric power system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Manweiler, R.W.

1975-11-01

The effects of a nuclear electromagnetic pulse (EMP) on the synchronous stability of the electric power transmission and distribution systems are evaluated. The various modes of coupling of EMP to the power system are briefly discussed, with particular emphasis on those perturbations affecting the synchronous stability of the transmission system. A brief review of the fundamental concepts of the stability problem is given, with a discussion of the general characteristics of transient analysis. A model is developed to represent single sets as well as repetitive sets of multiple faults on the distribution systems, as might be produced by EMP. Themore » results of many numerical stability calculations are presented to illustrate the transmission system's response from different types of perturbations. The important parameters of both multiple and repetitive faults are studied, including the dependence of the response on the size of the perturbed area, the fault density, and the effective impedance between the fault location and the transmission system. Both major load reduction and the effect of the opening of tie lines at the time of perturbation are also studied. We conclude that there is a high probability that EMP can induce perturbations on the distribution networks causing a large portion of the transmission network in the perturbed area to lose synchronism. The result would be an immediate and massive power failure. (auth)« less

An Autonomous Satellite Time Synchronization System Using Remotely Disciplined VC-OCXOs.

PubMed

Gu, Xiaobo; Chang, Qing; Glennon, Eamonn P; Xu, Baoda; Dempseter, Andrew G; Wang, Dun; Wu, Jiapeng

2015-07-23

An autonomous remote clock control system is proposed to provide time synchronization and frequency syntonization for satellite to satellite or ground to satellite time transfer, with the system comprising on-board voltage controlled oven controlled crystal oscillators (VC-OCXOs) that are disciplined to a remote master atomic clock or oscillator. The synchronization loop aims to provide autonomous operation over extended periods, be widely applicable to a variety of scenarios and robust. A new architecture comprising the use of frequency division duplex (FDD), synchronous time division (STDD) duplex and code division multiple access (CDMA) with a centralized topology is employed. This new design utilizes dual one-way ranging methods to precisely measure the clock error, adopts least square (LS) methods to predict the clock error and employs a third-order phase lock loop (PLL) to generate the voltage control signal. A general functional model for this system is proposed and the error sources and delays that affect the time synchronization are discussed. Related algorithms for estimating and correcting these errors are also proposed. The performance of the proposed system is simulated and guidance for selecting the clock is provided.

Queueing-Based Synchronization and Entrainment for Synthetic Gene Oscillators

NASA Astrophysics Data System (ADS)

Mather, William; Butzin, Nicholas; Hochendoner, Philip; Ogle, Curtis

Synthetic gene oscillators have been a major focus of synthetic biology research since the beginning of the field 15 years ago. They have proven to be useful both for biotechnological applications as well as a testing ground to significantly develop our understanding of the design principles behind synthetic and native gene oscillators. In particular, the principles governing synchronization and entrainment of biological oscillators have been explored using a synthetic biology approach. Our work combines experimental and theoretical approaches to specifically investigate how a bottleneck for protein degradation, which is present in most if not all existing synthetic oscillators, can be leveraged to robustly synchronize and entrain biological oscillators. We use both the terminology and mathematical tools of queueing theory to intuitively explain the role of this bottleneck in both synchronization and entrainment, which extends prior work demonstrating the usefulness of queueing theory in synthetic and native gene circuits. We conclude with an investigation of how synchronization and entrainment may be sensitive to the presence of multiple proteolytic pathways in a cell that couple weakly through crosstalk. This work was supported by NSF Grant #1330180.

Design and simulation of permanent magnet synchronous motor control system

NASA Astrophysics Data System (ADS)

Li, Li; Liu, Yongqiu

2018-06-01

In recent years, with the development of power electronics, microelectronics, new motor control theory and rare earth permanent magnet materials, permanent magnet synchronous motors have been rapidly applied. Permanent magnet synchronous motors have the advantages of small size, low loss and high efficiency. Today, energy conservation and environmental protection are increasingly valued. It is very necessary to study them. Permanent magnet synchronous motor control system has a wide range of application prospects in the fields of electric vehicles, ships and other transportation. Using the simulation function of MATLAB/SIMULINK, a modular design structure was used to simulate the whole system model of speed loop adjustment, current PI modulation, SVPWM (Space Vector Pulse Width Module) wave generation and double closed loop. The results show that this control method has good robustness, and this method can improve the design efficiency and shorten the system design time. In this article, the analysis of the control principle of modern permanent magnet synchronous motor and the various processes of MATLAB simulation application will be analyzed in detail. The basic theory, basic method and application technology of the permanent magnet synchronous motor control system are systematically introduced.

Synchronization in interdependent networks

NASA Astrophysics Data System (ADS)

Um, Jaegon; Minnhagen, Petter; Kim, Beom Jun

2011-06-01

We explore the synchronization behavior in interdependent systems, where the one-dimensional (1D) network (the intranetwork coupling strength JI) is ferromagnetically intercoupled (the strength J) to the Watts-Strogatz (WS) small-world network (the intranetwork coupling strength JII). In the absence of the internetwork coupling (J =0), the former network is well known not to exhibit the synchronized phase at any finite coupling strength, whereas the latter displays the mean-field transition. Through an analytic approach based on the mean-field approximation, it is found that for the weakly coupled 1D network (JI≪1) the increase of J suppresses synchrony, because the nonsynchronized 1D network becomes a heavier burden for the synchronization process of the WS network. As the coupling in the 1D network becomes stronger, it is revealed by the renormalization group (RG) argument that the synchronization is enhanced as JI is increased, implying that the more enhanced partial synchronization in the 1D network makes the burden lighter. Extensive numerical simulations confirm these expected behaviors, while exhibiting a reentrant behavior in the intermediate range of JI. The nonmonotonic change of the critical value of JII is also compared with the result from the numerical RG calculation.

A model explaining synchronization of neuron bioelectric frequency under weak alternating low frequency magnetic field

NASA Astrophysics Data System (ADS)

del Moral, A.; Azanza, María J.

2015-03-01

A biomagnetic-electrical model is presented that explains rather well the experimentally observed synchronization of the bioelectric potential firing rate ("frequency"), f, of single unit neurons of Helix aspersa mollusc under the application of extremely low frequency (ELF) weak alternating (AC) magnetic fields (MF). The proposed model incorporates to our widely experimentally tested model of superdiamagnetism (SD) and Ca2+ Coulomb explosion (CE) from lipid (LP) bilayer membrane (SD-CE model), the electrical quadrupolar long range interaction between the bilayer LP membranes of synchronized neuron pairs, not considered before. The quadrupolar interaction is capable of explaining well the observed synchronization. Actual extension of our SD-CE-model shows that the neuron firing frequency field, B, dependence becomes not modified, but the bioelectric frequency is decreased and its spontaneous temperature, T, dependence is modified. A comparison of the model with synchronization experimental results of pair of neurons under weak (B0 ≅0.2-15 mT) AC-MF of frequency fM=50 Hz is reported. From the deduced size of synchronized LP clusters under B, is suggested the formation of small neuron networks via the membrane lipid correlation.

Evidence for non-synchronous rotation of Europa. Galileo Imaging Team.

PubMed

Geissler, P E; Greenberg, R; Hoppa, G; Helfenstein, P; McEwen, A; Pappalardo, R; Tufts, R; Ockert-Bell, M; Sullivan, R; Greeley, R; Belton, M J; Denk, T; Clark, B; Burns, J; Veverka, J

1998-01-22

Non-synchronous rotation of Europa was predicted on theoretical grounds, by considering the orbitally averaged torque exerted by Jupiter on the satellite's tidal bulges. If Europa's orbit were circular, or the satellite were comprised of a frictionless fluid without tidal dissipation, this torque would average to zero. However, Europa has a small forced eccentricity e approximately 0.01 , generated by its dynamical interaction with Io and Ganymede, which should cause the equilibrium spin rate of the satellite to be slightly faster than synchronous. Recent gravity data suggest that there may be a permanent asymmetry in Europa's interior mass distribution which is large enough to offset the tidal torque; hence, if non-synchronous rotation is observed, the surface is probably decoupled from the interior by a subsurface layer of liquid or ductile ice. Non-synchronous rotation was invoked to explain Europa's global system of lineaments and an equatorial region of rifting seen in Voyager images. Here we report an analysis of the orientation and distribution of these surface features, based on initial observations made by the Galileo spacecraft. We find evidence that Europa spins faster than the synchronous rate (or did so in the past), consistent with the possibility of a global subsurface ocean.

Graph properties of synchronized cortical networks during visual working memory maintenance.

PubMed

Palva, Satu; Monto, Simo; Palva, J Matias

2010-02-15

Oscillatory synchronization facilitates communication in neuronal networks and is intimately associated with human cognition. Neuronal activity in the human brain can be non-invasively imaged with magneto- (MEG) and electroencephalography (EEG), but the large-scale structure of synchronized cortical networks supporting cognitive processing has remained uncharacterized. We combined simultaneous MEG and EEG (MEEG) recordings with minimum-norm-estimate-based inverse modeling to investigate the structure of oscillatory phase synchronized networks that were active during visual working memory (VWM) maintenance. Inter-areal phase-synchrony was quantified as a function of time and frequency by single-trial phase-difference estimates of cortical patches covering the entire cortical surfaces. The resulting networks were characterized with a number of network metrics that were then compared between delta/theta- (3-6 Hz), alpha- (7-13 Hz), beta- (16-25 Hz), and gamma- (30-80 Hz) frequency bands. We found several salient differences between frequency bands. Alpha- and beta-band networks were more clustered and small-world like but had smaller global efficiency than the networks in the delta/theta and gamma bands. Alpha- and beta-band networks also had truncated-power-law degree distributions and high k-core numbers. The data converge on showing that during the VWM-retention period, human cortical alpha- and beta-band networks have a memory-load dependent, scale-free small-world structure with densely connected core-like structures. These data further show that synchronized dynamic networks underlying a specific cognitive state can exhibit distinct frequency-dependent network structures that could support distinct functional roles. Copyright 2009 Elsevier Inc. All rights reserved.

Molecular profiling of synchronous and metachronous cancers of the pancreas reveal molecular mimicry between samples from the same patient.

PubMed

Talbott, Vanessa A; Yeo, Charles J; Brody, Jonathan R; Witkiewicz, Agnieszka K

2012-07-01

Pancreatic ductal adenocarcinoma (PDA) is rarely a survivable disease. In rare cases, separate synchronous tumors are discovered at the time of resection, while in others, patients present with a metachronous cancer after prior surgical resection. Studying molecular markers of synchronous and metachronous lesions may aid to clarify the biology of this often deadly disease. Two patients presented with synchronous tumors (each one with a tumor in the pancreatic head/neck and the other in the tail, designated patients A and B). An additional patient (patient C) underwent an R0 resection for PDA of the head and recurred 1.5 y later with PDA in the tail. Genomic DNA was laser capture microdissected (LCM) from the tumor and molecular analysis was performed. K-ras status and loss of heterozygosity (LOH) were determined from multiple specimens for each case. All samples from each patient harbored identical K-ras mutations. In patient A, the tumor at the head of the pancreas had more clonal genetic instability as reflected by LOH analysis over multiple LCM samples. Patient B had more genetic instability in the tail lesion compared with the neck. Patient C had virtually the identical molecular profile in both tumors, supporting the notion that both tumors were related. We conclude that the synchronous and metachronous tumors likely are initiated from identical precursor lesions and/or events (i.e., K-ras mutations). Future studies will need to investigate if these tumors will respond similarly to adjuvant therapies targeted against the clonal molecular events in the tumor. Copyright © 2012 Elsevier Inc. All rights reserved.

Motor correlates of models of secondary bilateral synchrony and multiple epileptic foci.

PubMed

Jiruska, Premysl; Proks, Jan; Otáhal, Jakub; Mares, Pavel

2007-10-01

Bilateral synchronous epileptiform discharges registered in patients with partial epilepsies may be generated by different pathophysiological mechanisms. Differentiation between underlying mechanisms is often crucial for correct diagnosis and adequate treatment in clinical epileptology. The aim of this study was to model in rats two possible mechanisms--secondary bilateral sychrony and interaction between multiple epilepic foci. Furthermore, to describe in detail semiology, laterality and differences in motor phenomena. Secondary bilateral synchrony was modeled by unilateral topical application of bicuculline methiodide (BMI) over the sensorimotor cortex. Bilateral symmetric application of BMI was used as a model of multiple epileptic foci. Electrographic and behavioural phenomena were recorded for 1h following the application of BMI. Electroencephalogram in both groups was characterized by presence of bilateral synchronous discharges. Myoclonic and clonic seizures involving forelimb and head muscles represented the most common motor seizure pattern in both groups. Significant differences were found in the laterality of motor phenomena. Motor seizures in unilateral foci always started in the contralateral limbs whereas symmetrical foci exhibited bilateral independent onset of convulsions. Similar lateralization was observed in interictal motor phenomena (myoclonic jerks). An important influence of posture on epileptic motor phenomena was demonstrated. Active or passive changes in animal posture (verticalization to bipedal posture) caused conversion from unilateral myoclonic jerks or clonic seizures to bilaterally synchronous (generalized) motor phenomena in both groups.

Student Perceptions of Online Writing Center Designs for Fully Online Programs

ERIC Educational Resources Information Center

Simpson, Shelah Y.

2017-01-01

In this multiple-case study, the author investigated fully online students' perceptions of and experiences with asynchronous and synchronous writing support options of an institutional writing center and a commercial tutoring service. This dissertation used a multiple-case study design (Merriam, 1998, 2009; Yin, 2009) to ascertain which features…

Universal filtered multi-carrier system for asynchronous uplink transmission in optical access network

NASA Astrophysics Data System (ADS)

Kang, Soo-Min; Kim, Chang-Hun; Han, Sang-Kook

2016-02-01

In passive optical network (PON), orthogonal frequency division multiplexing (OFDM) has been studied actively due to its advantages such as high spectra efficiency (SE), dynamic resource allocation in time or frequency domain, and dispersion robustness. However, orthogonal frequency division multiple access (OFDMA)-PON requires tight synchronization among multiple access signals. If not, frequency orthogonality could not be maintained. Also its sidelobe causes inter-channel interference (ICI) to adjacent channel. To prevent ICI caused by high sidelobes, guard band (GB) is usually used which degrades SE. Thus, OFDMA-PON is not suitable for asynchronous uplink transmission in optical access network. In this paper, we propose intensity modulation/direct detection (IM/DD) based universal filtered multi-carrier (UFMC) PON for asynchronous multiple access. The UFMC uses subband filtering to subsets of subcarriers. Since it reduces sidelobe of each subband by applying subband filtering, it could achieve better performance compared to OFDM. For the experimental demonstration, different sample delay was applied to subbands to implement asynchronous transmission condition. As a result, time synchronization robustness of UFMC was verified in asynchronous multiple access system.

Flexible Language Constructs for Large Parallel Programs

DOE PAGES

Rosing, Matt; Schnabel, Robert

1994-01-01

The goal of the research described in this article is to develop flexible language constructs for writing large data parallel numerical programs for distributed memory (multiple instruction multiple data [MIMD]) multiprocessors. Previously, several models have been developed to support synchronization and communication. Models for global synchronization include single instruction multiple data (SIMD), single program multiple data (SPMD), and sequential programs annotated with data distribution statements. The two primary models for communication include implicit communication based on shared memory and explicit communication based on messages. None of these models by themselves seem sufficient to permit the natural and efficient expression ofmore » the variety of algorithms that occur in large scientific computations. In this article, we give an overview of a new language that combines many of these programming models in a clean manner. This is done in a modular fashion such that different models can be combined to support large programs. Within a module, the selection of a model depends on the algorithm and its efficiency requirements. In this article, we give an overview of the language and discuss some of the critical implementation details.« less

Synchronous and metachronous neoplasms in gastric cancer patients: A 23-year study

PubMed Central

Ławniczak, Małgorzata; Gawin, Alicja; Jaroszewicz-Heigelmann, Halina; Rogoza-Mateja, Wiesława; Raszeja-Wyszomirska, Joanna; Białek, Andrzej; Karpińska-Kaczmarczyk, Katarzyna; Starzyńska, Teresa

2014-01-01

AIM: To determine the prevalence and characteristics of additional primary malignancies in gastric cancer (GC) patients. METHODS: GC patients (862 total; 570 men, 292 women; mean age 59.8 ± 12.8 years) diagnosed at the Department of Gastroenterology at Pomeranian Medical University over a period of 23 years were included in this retrospective analysis of a prospectively maintained database. Mean follow-up time was 31.3 ± 38.6 mo (range 1-241 mo). The following clinicopathological features of patients with synchronous tumors were compared to those with metachronous tumors: age, sex, symptom duration, family history of cancer, tumor site, stage (early vs advanced), histology, and blood group. GC patients with and without a second tumor were compared in terms of the same clinicopathological features. RESULTS: Of 862 GC patients, 58 (6.7%) developed a total of 62 multiple primary tumors, of which 39 (63%) were metachronous and 23 (37%) synchronous. Four (6.9%) of the 58 multiple GC patients developed two or more neoplasms. The predominant tumor type of the secondary neoplasms was colorectal (n = 17), followed by lung (n = 9), breast (n = 8), and prostate (n = 7). Age was the only clinicopathological feature that differed between GC patients with synchronous vs metachronous malignancies; GC patients with synchronous neoplasms were older than those with metachronous neoplasms (68.0 ± 10.3 years vs 59.9 ± 11.1 years, respectively, P = 0.008). Comparisons between patients with and without a second primary cancer revealed that the only statistically significant differences were in age and blood group. The mean age of the patients with multiple GC was higher than that of those without a second primary tumor (63.4 ± 11.4 years vs 59.5 ± 13.0 years, respectively, P = 0.026). GC patients with a second primary tumor were more commonly blood group O than those without (56.2% vs 31.6%, respectively, P = 0.002). CONCLUSION: GC patients may develop other primary cancers; appropriate preoperative and postoperative diagnostic modalities are thus required, particularly if patients are older and blood group O. PMID:24966619

Synchronization of random bit generators based on coupled chaotic lasers and application to cryptography.

PubMed

Kanter, Ido; Butkovski, Maria; Peleg, Yitzhak; Zigzag, Meital; Aviad, Yaara; Reidler, Igor; Rosenbluh, Michael; Kinzel, Wolfgang

2010-08-16

Random bit generators (RBGs) constitute an important tool in cryptography, stochastic simulations and secure communications. The later in particular has some difficult requirements: high generation rate of unpredictable bit strings and secure key-exchange protocols over public channels. Deterministic algorithms generate pseudo-random number sequences at high rates, however, their unpredictability is limited by the very nature of their deterministic origin. Recently, physical RBGs based on chaotic semiconductor lasers were shown to exceed Gbit/s rates. Whether secure synchronization of two high rate physical RBGs is possible remains an open question. Here we propose a method, whereby two fast RBGs based on mutually coupled chaotic lasers, are synchronized. Using information theoretic analysis we demonstrate security against a powerful computational eavesdropper, capable of noiseless amplification, where all parameters are publicly known. The method is also extended to secure synchronization of a small network of three RBGs.

Stabilization and synchronization for a mechanical system via adaptive sliding mode control.

PubMed

Song, Zhankui; Sun, Kaibiao; Ling, Shuai

2017-05-01

In this paper, we investigate the synchronization problem of chaotic centrifugal flywheel governor with parameters uncertainty and lumped disturbances. A slave centrifugal flywheel governor system is considered as an underactuated following-system which a control input is designed to follow a master centrifugal flywheel governor system. To tackle lumped disturbances and uncertainty parameters, a novel synchronization control law is developed by employing sliding mode control strategy and Nussbaum gain technique. Adaptation updating algorithms are derived in the sense of Lyapunov stability analysis such that the lumped disturbances can be suppressed and the adverse effect caused by uncertainty parameters can be compensated. In addition, the synchronization tracking-errors are proven to converge to a small neighborhood of the origin. Finally, simulation results demonstrate the effectiveness of the proposed control scheme. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.

Specificity of V1-V2 Orientation Networks in the Primate Visual Cortex

PubMed Central

Roe, Anna W.; Ts'o, Daniel Y.

2015-01-01

The computation of texture and shape involves integration of features of various orientations. Orientation networks within V1 tend to involve cells which share similar orientation selectivity. However, emergent properties in V2 require the integration of multiple orientations. We now show that, unlike interactions within V1, V1-V2 orientation interactions are much less synchronized and are not necessarily orientation dependent. We find V1-V2 orientation networks are of two types: a more tightly synchronized, orientation-preserving network and a less synchronized orientation-diverse network. We suggest that such diversity of V1-V2 interactions underlies the spatial and functional integration required for computation of higher order contour and shape in V2. PMID:26314798

Gastric marginal zone lymphoma of mucosa-associated lymphoid tissue and signet ring cell carcinoma, synchronous collision tumour of the stomach: a case report.

PubMed

George, Smiley Annie; Junaid, T A

2014-01-01

To report a rare case of synchronous marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) signet ring cell carcinoma occurring as a collision tumour in the stomach. A 53-year-old man was diagnosed initially with signet ring cell carcinoma of the stomach. The microscopy of the subsequent total gastrectomy revealed a collision tumour of MALT lymphoma and signet ring cell carcinoma associated with Helicobacter pylori gastritis. This case highlighted the importance of a careful evaluation of the accompanying lymphoid population in the biopsy samples of gastric adenocarcinoma and underlined the need for multiple endoscopic biopsies to detect these rare synchronous tumours. © 2013 S. Karger AG, Basel.

Gastric Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue and Signet Ring Cell Carcinoma, Synchronous Collision Tumour of the Stomach: A Case Report

PubMed Central

George, Smiley Annie; Junaid, T.A.

2014-01-01

Objective To report a rare case of synchronous marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) signet ring cell carcinoma occurring as a collision tumour in the stomach. Clinical Presentation and Intervention A 53-year-old man was diagnosed initially with signet ring cell carcinoma of the stomach. The microscopy of the subsequent total gastrectomy revealed a collision tumour of MALT lymphoma and signet ring cell carcinoma associated with Helicobacter pylori gastritis. Conclusion This case highlighted the importance of a careful evaluation of the accompanying lymphoid population in the biopsy samples of gastric adenocarcinoma and underlined the need for multiple endoscopic biopsies to detect these rare synchronous tumours. PMID:24247357

Collaborative voxel-based surgical virtual environments.

PubMed

Acosta, Eric; Muniz, Gilbert; Armonda, Rocco; Bowyer, Mark; Liu, Alan

2008-01-01

Virtual Reality-based surgical simulators can utilize Collaborative Virtual Environments (C-VEs) to provide team-based training. To support real-time interactions, C-VEs are typically replicated on each user's local computer and a synchronization method helps keep all local copies consistent. This approach does not work well for voxel-based C-VEs since large and frequent volumetric updates make synchronization difficult. This paper describes a method that allows multiple users to interact within a voxel-based C-VE for a craniotomy simulator being developed. Our C-VE method requires smaller update sizes and provides faster synchronization update rates than volumetric-based methods. Additionally, we address network bandwidth/latency issues to simulate networked haptic and bone drilling tool interactions with a voxel-based skull C-VE.

Synchronization of two homodromy rotors installed on a double vibro-body in a coupling vibration system.

PubMed

Fang, Pan; Hou, Yongjun; Nan, Yanghai

2015-01-01

A new mechanism is proposed to implement synchronization of the two unbalanced rotors in a vibration system, which consists of a double vibro-body, two induction motors and spring foundations. The coupling relationship between the vibro-bodies is ascertained with the Laplace transformation method for the dynamics equation of the system obtained with the Lagrange's equation. An analytical approach, the average method of modified small parameters, is employed to study the synchronization characteristics between the two unbalanced rotors, which is converted into that of existence and the stability of zero solutions for the non-dimensional differential equations of the angular velocity disturbance parameters. By assuming the disturbance parameters that infinitely approach to zero, the synchronization condition for the two rotors is obtained. It indicated that the absolute value of the residual torque between the two motors should be equal to or less than the maximum of their coupling torques. Meanwhile, the stability criterion of synchronization is derived with the Routh-Hurwitz method, and the region of the stable phase difference is confirmed. At last, computer simulations are preformed to verify the correctness of the approximate solution of the theoretical computation for the stable phase difference between the two unbalanced rotors, and the results of theoretical computation is in accordance with that of computer simulations. To sum up, only the parameters of the vibration system satisfy the synchronization condition and the stability criterion of the synchronization, the two unbalanced rotors can implement the synchronization operation.

Synchronization of Two Homodromy Rotors Installed on a Double Vibro-Body in a Coupling Vibration System

PubMed Central

Fang, Pan; Hou, Yongjun; Nan, Yanghai

2015-01-01

A new mechanism is proposed to implement synchronization of the two unbalanced rotors in a vibration system, which consists of a double vibro-body, two induction motors and spring foundations. The coupling relationship between the vibro-bodies is ascertained with the Laplace transformation method for the dynamics equation of the system obtained with the Lagrange’s equation. An analytical approach, the average method of modified small parameters, is employed to study the synchronization characteristics between the two unbalanced rotors, which is converted into that of existence and the stability of zero solutions for the non-dimensional differential equations of the angular velocity disturbance parameters. By assuming the disturbance parameters that infinitely approach to zero, the synchronization condition for the two rotors is obtained. It indicated that the absolute value of the residual torque between the two motors should be equal to or less than the maximum of their coupling torques. Meanwhile, the stability criterion of synchronization is derived with the Routh-Hurwitz method, and the region of the stable phase difference is confirmed. At last, computer simulations are preformed to verify the correctness of the approximate solution of the theoretical computation for the stable phase difference between the two unbalanced rotors, and the results of theoretical computation is in accordance with that of computer simulations. To sum up, only the parameters of the vibration system satisfy the synchronization condition and the stability criterion of the synchronization, the two unbalanced rotors can implement the synchronization operation. PMID:25993472

[Triple synchronous primary gynaecological tumours. A case report].

PubMed

Gutiérrez-Palomino, Laura; Romo-de Los Reyes, José María; Pareja-Megía, María Jesús; García-Mejido, José Antonio

2016-01-01

Synchronous multiple primary malignancies in the female genital tract are infrequent. From 50 to 70% of them corresponds to synchronous cancers of the endometrium and ovary. To our knowledge, this is only the third case report in the international literature of three concurrent gynaecological cancers of epithelial origin. A case is presented, as well as a literature review due to the infrequency of its diagnosis and the lack of information on the subject. A 49-year-old woman, with previous gynaecological history of ovarian endometriosis. She underwent a hysterectomy and bilateral oophorectomy, as she had been diagnosed with endometrial hyperplasia with atypia. The final histopathology reported synchronous ovarian, Fallopian tube, and endometrial cancer. An extension study and complete surgical staging was performed, both being negative. She received adjuvant treatment of chemotherapy and radiotherapy. She is currently free of disease. The aetiology is uncertain. There is controversy relating to increased susceptibility of synchronous neoplasms to pelvic endometriosis and inherited genetic syndromes. Its diagnosis needs to differentiate them from metastatic disease. Additionally, they are problematical from a clinical, diagnostic, therapeutic, and prognostic point of view. The presentation of more cases of triple synchronous cancers is necessary for a complete adjuvant and surgical treatment. Copyright © 2015 Academia Mexicana de Cirugía A.C. Published by Masson Doyma México S.A. All rights reserved.

Deconstruction of spatial integrity in visual stimulus detected by modulation of synchronized activity in cat visual cortex.

PubMed

Zhou, Zhiyi; Bernard, Melanie R; Bonds, A B

2008-04-02

Spatiotemporal relationships among contour segments can influence synchronization of neural responses in the primary visual cortex. We performed a systematic study to dissociate the impact of spatial and temporal factors in the signaling of contour integration via synchrony. In addition, we characterized the temporal evolution of this process to clarify potential underlying mechanisms. With a 10 x 10 microelectrode array, we recorded the simultaneous activity of multiple cells in the cat primary visual cortex while stimulating with drifting sine-wave gratings. We preserved temporal integrity and systematically degraded spatial integrity of the sine-wave gratings by adding spatial noise. Neural synchronization was analyzed in the time and frequency domains by conducting cross-correlation and coherence analyses. The general association between neural spike trains depends strongly on spatial integrity, with coherence in the gamma band (35-70 Hz) showing greater sensitivity to the change of spatial structure than other frequency bands. Analysis of the temporal dynamics of synchronization in both time and frequency domains suggests that spike timing synchronization is triggered nearly instantaneously by coherent structure in the stimuli, whereas frequency-specific oscillatory components develop more slowly, presumably through network interactions. Our results suggest that, whereas temporal integrity is required for the generation of synchrony, spatial integrity is critical in triggering subsequent gamma band synchronization.

Defense Acquisition Research Journal. Volume 20, Number 3, Issue 67, October 2013

DTIC Science & Technology

2013-10-01

Contracting Operations (PZCO) FIGURE 4. CONTRACTING PHASE ZERO: PLAN, EXERCISE, REHEARSE, AND SYNCHRONIZE Note. BPA = Blanket Purchase Agreement; COCO...Construction Supplies; Oce Equipment; Quality of Life; and Morale, Welfare, and Recreation PO/TO/DO/ BPA Small Purchase Standard Vehicles PO/TO/DO/ BPA Small...Purchase Standard Vehicles PO/TO/DO/ BPA Small Purchase Standard Vehicles PO/TO/DO/ BPA Small Purchase Food, Water, Billeting, Hygiene; Transportation

Multiple neoplasms, single primaries, and patient survival

PubMed Central

Amer, Magid H

2014-01-01

Background Multiple primary neoplasms in surviving cancer patients are relatively common, with an increasing incidence. Their impact on survival has not been clearly defined. Methods This was a retrospective review of clinical data for all consecutive patients with histologically confirmed cancer, with emphasis on single versus multiple primary neoplasms. Second primaries discovered at the workup of the index (first) primary were termed simultaneous, if discovered within 6 months of the index primary were called synchronous, and if discovered after 6 months were termed metachronous. Results Between 2005 and 2012, of 1,873 cancer patients, 322 developed second malignancies; these included two primaries (n=284), and three or more primaries (n=38). Forty-seven patients had synchronous primaries and 275 had metachronous primaries. Patients with multiple primaries were predominantly of Caucasian ancestry (91.0%), with a tendency to develop thrombosis (20.2%), had a strong family history of similar cancer (22.3%), and usually presented with earlier stage 0 through stage II disease (78.9%). When compared with 1,551 patients with a single primary, these figures were 8.9%, 15.6%, 18.3%, and 50.9%, respectively (P≤0.001). Five-year survival rates were higher for metachronous cancers (95%) than for synchronous primaries (59%) and single primaries (59%). The worst survival rate was for simultaneous concomitant multiple primaries, being a median of 1.9 years. The best survival was for patients with three or more primaries (median 10.9 years) and was similar to the expected survival for the age-matched and sex-matched general population (P=0.06991). Conclusion Patients with multiple primaries are usually of Caucasian ancestry, have less aggressive malignancies, present at earlier stages, frequently have a strong family history of similar cancer, and their cancers tend to have indolent clinical behavior with longer survival rates, possibly related to genetic predisposition. PMID:24623992

Decentralized diagnostics based on a distributed micro-genetic algorithm for transducer networks monitoring large experimental systems.

PubMed

Arpaia, P; Cimmino, P; Girone, M; La Commara, G; Maisto, D; Manna, C; Pezzetti, M

2014-09-01

Evolutionary approach to centralized multiple-faults diagnostics is extended to distributed transducer networks monitoring large experimental systems. Given a set of anomalies detected by the transducers, each instance of the multiple-fault problem is formulated as several parallel communicating sub-tasks running on different transducers, and thus solved one-by-one on spatially separated parallel processes. A micro-genetic algorithm merges evaluation time efficiency, arising from a small-size population distributed on parallel-synchronized processors, with the effectiveness of centralized evolutionary techniques due to optimal mix of exploitation and exploration. In this way, holistic view and effectiveness advantages of evolutionary global diagnostics are combined with reliability and efficiency benefits of distributed parallel architectures. The proposed approach was validated both (i) by simulation at CERN, on a case study of a cold box for enhancing the cryogeny diagnostics of the Large Hadron Collider, and (ii) by experiments, under the framework of the industrial research project MONDIEVOB (Building Remote Monitoring and Evolutionary Diagnostics), co-funded by EU and the company Del Bo srl, Napoli, Italy.

The two-way time synchronization system via a satellite voice channel

NASA Technical Reports Server (NTRS)

Heng-Qiu, Zheng; Ren-Huan, Zhang; Yong-Hui, HU

1994-01-01

A newly developed two-way time synchronization system is described in this paper. The system uses one voice channel at a SCPC satellite digital communication earth station, whose bandwidth is only 45 kHz, thus saving satellite resources greatly. The system is composed of one master station and one or several, up to sixty-two, secondary stations. The master and secondary stations are equipped with the same equipment, including a set of timing equipment, a synthetic data terminal for time synchronizing, and a interface unit between the data terminal and the satellite earth station. The synthetic data terminal for time synchronization also has an IRIG-B code generator and a translator. The data terminal of master station is the key part of whole system. The system synchronization process is full automatic, which is controlled by the master station. Employing an autoscanning technique and conversational mode, the system accomplishes the following tasks: linking up liaison with each secondary station in turn, establishing a coarse time synchronization, calibrating date (years, months, days) and time of day (hours, minutes, seconds), precisely measuring the time difference between local station and the opposite station, exchanging measurement data, statistically processing the data, rejecting error terms, printing the data, calculating the clock difference and correcting the phase, thus realizing real-time synchronization from one point to multiple points. We also designed an adaptive phase circuit to eliminate the phase ambiguity of the PSK demodulator. The experiments have shown that the time synchronization accuracy is better than 2 mu S. The system has been put into regular operation.

Sensorimotor Synchronization with Different Metrical Levels of Point-Light Dance Movements

PubMed Central

Su, Yi-Huang

2016-01-01

Rhythm perception and synchronization have been extensively investigated in the auditory domain, as they underlie means of human communication such as music and speech. Although recent studies suggest comparable mechanisms for synchronizing with periodically moving visual objects, the extent to which it applies to ecologically relevant information, such as the rhythm of complex biological motion, remains unknown. The present study addressed this issue by linking rhythm of music and dance in the framework of action-perception coupling. As a previous study showed that observers perceived multiple metrical periodicities in dance movements that embodied this structure, the present study examined whether sensorimotor synchronization (SMS) to dance movements resembles what is known of auditory SMS. Participants watched a point-light figure performing two basic steps of Swing dance cyclically, in which the trunk bounced at every beat and the limbs moved at every second beat, forming two metrical periodicities. Participants tapped synchronously to the bounce of the trunk with or without the limbs moving in the stimuli (Experiment 1), or tapped synchronously to the leg movements with or without the trunk bouncing simultaneously (Experiment 2). Results showed that, while synchronization with the bounce (lower-level pulse) was not influenced by the presence or absence of limb movements (metrical accent), synchronization with the legs (beat) was improved by the presence of the bounce (metrical subdivision) across different movement types. The latter finding parallels the “subdivision benefit” often demonstrated in auditory tasks, suggesting common sensorimotor mechanisms for visual rhythms in dance and auditory rhythms in music. PMID:27199709

Small-group, computer-mediated argumentation in middle-school classrooms: the effects of gender and different types of online teacher guidance.

PubMed

Asterhan, Christa S C; Schwarz, Baruch B; Gil, Julia

2012-09-01

Research has shown the importance of careful teacher support during collaborative group work to promote productive discourse between students (Webb, 2009). However, this research has traditionally focused on face-to-face communication. The role of online teacher guidance of small-group computer-mediated discussions has received little attention, especially in secondary school classroom settings. Researchers of computer-supported collaborative learning (CSCL), on the other hand, have traditionally focused on software-embedded features, such as scripts, to support a-synchronous peer dialogue, and less so on human guidance of synchronous group discussions. The main aim of the present in vivo, experimental study is to examine whether online teacher guidance can improve the quality of small-group synchronous discussions, and whether different types of guidance (epistemic or interaction guidance) affect these discussions differently, when compared to an unguided condition. The second goal of this study is to explore potential differences between all-female and all-male discussion groups. Eighty-two 9th graders (three classrooms) and six teachers from a rural high school in Israel. Whereas epistemic guidance only improved aspects of the argumentative quality of the discussion, interaction guidance only improved aspects of collaboration. Discussions of all-girls groups scored higher on aspects of collaboration and argumentative quality, compared to all-boys groups. The findings show that teacher guidance of synchronous, online discussions in classrooms is realizable and reasonably reaches its intended goals. Training should be focused on acquiring various guidance strategies to augment their beneficial effects. Furthermore, future research should pay more attention to potential gender differences in peer-to-peer argumentation. ©2011 The British Psychological Society.

Synchronization of mobile chaotic oscillator networks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fujiwara, Naoya, E-mail: fujiwara@csis.u-tokyo.ac.jp; Kurths, Jürgen; Díaz-Guilera, Albert

We study synchronization of systems in which agents holding chaotic oscillators move in a two-dimensional plane and interact with nearby ones forming a time dependent network. Due to the uncertainty in observing other agents' states, we assume that the interaction contains a certain amount of noise that turns out to be relevant for chaotic dynamics. We find that a synchronization transition takes place by changing a control parameter. But this transition depends on the relative dynamic scale of motion and interaction. When the topology change is slow, we observe an intermittent switching between laminar and burst states close to themore » transition due to small noise. This novel type of synchronization transition and intermittency can happen even when complete synchronization is linearly stable in the absence of noise. We show that the linear stability of the synchronized state is not a sufficient condition for its stability due to strong fluctuations of the transverse Lyapunov exponent associated with a slow network topology change. Since this effect can be observed within the linearized dynamics, we can expect such an effect in the temporal networks with noisy chaotic oscillators, irrespective of the details of the oscillator dynamics. When the topology change is fast, a linearized approximation describes well the dynamics towards synchrony. These results imply that the fluctuations of the finite-time transverse Lyapunov exponent should also be taken into account to estimate synchronization of the mobile contact networks.« less

10-fs-level synchronization of photocathode laser with RF-oscillator for ultrafast electron and X-ray sources

PubMed Central

Yang, Heewon; Han, Byungheon; Shin, Junho; Hou, Dong; Chung, Hayun; Baek, In Hyung; Jeong, Young Uk; Kim, Jungwon

2017-01-01

Ultrafast electron-based coherent radiation sources, such as free-electron lasers (FELs), ultrafast electron diffraction (UED) and Thomson-scattering sources, are becoming more important sources in today’s ultrafast science. Photocathode laser is an indispensable common subsystem in these sources that generates ultrafast electron pulses. To fully exploit the potentials of these sources, especially for pump-probe experiments, it is important to achieve high-precision synchronization between the photocathode laser and radio-frequency (RF) sources that manipulate electron pulses. So far, most of precision laser-RF synchronization has been achieved by using specially designed low-noise Er-fibre lasers at telecommunication wavelength. Here we show a modular method that achieves long-term (>1 day) stable 10-fs-level synchronization between a commercial 79.33-MHz Ti:sapphire laser oscillator and an S-band (2.856-GHz) RF oscillator. This is an important first step toward a photocathode laser-based femtosecond RF timing and synchronization system that is suitable for various small- to mid-scale ultrafast X-ray and electron sources. PMID:28067288

10-fs-level synchronization of photocathode laser with RF-oscillator for ultrafast electron and X-ray sources

NASA Astrophysics Data System (ADS)

Yang, Heewon; Han, Byungheon; Shin, Junho; Hou, Dong; Chung, Hayun; Baek, In Hyung; Jeong, Young Uk; Kim, Jungwon

2017-01-01

Ultrafast electron-based coherent radiation sources, such as free-electron lasers (FELs), ultrafast electron diffraction (UED) and Thomson-scattering sources, are becoming more important sources in today’s ultrafast science. Photocathode laser is an indispensable common subsystem in these sources that generates ultrafast electron pulses. To fully exploit the potentials of these sources, especially for pump-probe experiments, it is important to achieve high-precision synchronization between the photocathode laser and radio-frequency (RF) sources that manipulate electron pulses. So far, most of precision laser-RF synchronization has been achieved by using specially designed low-noise Er-fibre lasers at telecommunication wavelength. Here we show a modular method that achieves long-term (>1 day) stable 10-fs-level synchronization between a commercial 79.33-MHz Ti:sapphire laser oscillator and an S-band (2.856-GHz) RF oscillator. This is an important first step toward a photocathode laser-based femtosecond RF timing and synchronization system that is suitable for various small- to mid-scale ultrafast X-ray and electron sources.

10-fs-level synchronization of photocathode laser with RF-oscillator for ultrafast electron and X-ray sources.

PubMed

Yang, Heewon; Han, Byungheon; Shin, Junho; Hou, Dong; Chung, Hayun; Baek, In Hyung; Jeong, Young Uk; Kim, Jungwon

2017-01-09

Ultrafast electron-based coherent radiation sources, such as free-electron lasers (FELs), ultrafast electron diffraction (UED) and Thomson-scattering sources, are becoming more important sources in today's ultrafast science. Photocathode laser is an indispensable common subsystem in these sources that generates ultrafast electron pulses. To fully exploit the potentials of these sources, especially for pump-probe experiments, it is important to achieve high-precision synchronization between the photocathode laser and radio-frequency (RF) sources that manipulate electron pulses. So far, most of precision laser-RF synchronization has been achieved by using specially designed low-noise Er-fibre lasers at telecommunication wavelength. Here we show a modular method that achieves long-term (>1 day) stable 10-fs-level synchronization between a commercial 79.33-MHz Ti:sapphire laser oscillator and an S-band (2.856-GHz) RF oscillator. This is an important first step toward a photocathode laser-based femtosecond RF timing and synchronization system that is suitable for various small- to mid-scale ultrafast X-ray and electron sources.

A hierarchical model of daily stream temperature using air-water temperature synchronization, autocorrelation, and time lags

USGS Publications Warehouse

Letcher, Benjamin; Hocking, Daniel; O'Neil, Kyle; Whiteley, Andrew R.; Nislow, Keith H.; O'Donnell, Matthew

2016-01-01

Water temperature is a primary driver of stream ecosystems and commonly forms the basis of stream classifications. Robust models of stream temperature are critical as the climate changes, but estimating daily stream temperature poses several important challenges. We developed a statistical model that accounts for many challenges that can make stream temperature estimation difficult. Our model identifies the yearly period when air and water temperature are synchronized, accommodates hysteresis, incorporates time lags, deals with missing data and autocorrelation and can include external drivers. In a small stream network, the model performed well (RMSE = 0.59°C), identified a clear warming trend (0.63 °C decade−1) and a widening of the synchronized period (29 d decade−1). We also carefully evaluated how missing data influenced predictions. Missing data within a year had a small effect on performance (∼0.05% average drop in RMSE with 10% fewer days with data). Missing all data for a year decreased performance (∼0.6 °C jump in RMSE), but this decrease was moderated when data were available from other streams in the network.

Rhythm Patterns Interaction - Synchronization Behavior for Human-Robot Joint Action

PubMed Central

Mörtl, Alexander; Lorenz, Tamara; Hirche, Sandra

2014-01-01

Interactive behavior among humans is governed by the dynamics of movement synchronization in a variety of repetitive tasks. This requires the interaction partners to perform for example rhythmic limb swinging or even goal-directed arm movements. Inspired by that essential feature of human interaction, we present a novel concept and design methodology to synthesize goal-directed synchronization behavior for robotic agents in repetitive joint action tasks. The agents’ tasks are described by closed movement trajectories and interpreted as limit cycles, for which instantaneous phase variables are derived based on oscillator theory. Events segmenting the trajectories into multiple primitives are introduced as anchoring points for enhanced synchronization modes. Utilizing both continuous phases and discrete events in a unifying view, we design a continuous dynamical process synchronizing the derived modes. Inverse to the derivation of phases, we also address the generation of goal-directed movements from the behavioral dynamics. The developed concept is implemented to an anthropomorphic robot. For evaluation of the concept an experiment is designed and conducted in which the robot performs a prototypical pick-and-place task jointly with human partners. The effectiveness of the designed behavior is successfully evidenced by objective measures of phase and event synchronization. Feedback gathered from the participants of our exploratory study suggests a subjectively pleasant sense of interaction created by the interactive behavior. The results highlight potential applications of the synchronization concept both in motor coordination among robotic agents and in enhanced social interaction between humanoid agents and humans. PMID:24752212

Cardiac and respiratory patterns synchronize between persons during choir singing.

PubMed

Müller, Viktor; Lindenberger, Ulman

2011-01-01

Dyadic and collective activities requiring temporally coordinated action are likely to be associated with cardiac and respiratory patterns that synchronize within and between people. However, the extent and functional significance of cardiac and respiratory between-person couplings have not been investigated thus far. Here, we report interpersonal oscillatory couplings among eleven singers and one conductor engaged in choir singing. We find that: (a) phase synchronization both in respiration and heart rate variability increase significantly during singing relative to a rest condition; (b) phase synchronization is higher when singing in unison than when singing pieces with multiple voice parts; (c) directed coupling measures are consistent with the presence of causal effects of the conductor on the singers at high modulation frequencies; (d) the different voices of the choir are reflected in network analyses of cardiac and respiratory activity based on graph theory. Our results suggest that oscillatory coupling of cardiac and respiratory patterns provide a physiological basis for interpersonal action coordination.

Cardiac and Respiratory Patterns Synchronize between Persons during Choir Singing

PubMed Central

Müller, Viktor; Lindenberger, Ulman

2011-01-01

Dyadic and collective activities requiring temporally coordinated action are likely to be associated with cardiac and respiratory patterns that synchronize within and between people. However, the extent and functional significance of cardiac and respiratory between-person couplings have not been investigated thus far. Here, we report interpersonal oscillatory couplings among eleven singers and one conductor engaged in choir singing. We find that: (a) phase synchronization both in respiration and heart rate variability increase significantly during singing relative to a rest condition; (b) phase synchronization is higher when singing in unison than when singing pieces with multiple voice parts; (c) directed coupling measures are consistent with the presence of causal effects of the conductor on the singers at high modulation frequencies; (d) the different voices of the choir are reflected in network analyses of cardiac and respiratory activity based on graph theory. Our results suggest that oscillatory coupling of cardiac and respiratory patterns provide a physiological basis for interpersonal action coordination. PMID:21957466

Superdiffusion, large-scale synchronization, and topological defects

NASA Astrophysics Data System (ADS)

Großmann, Robert; Peruani, Fernando; Bär, Markus

2016-04-01

We study an ensemble of random walkers carrying internal noisy phase oscillators which are synchronized among the walkers by local interactions. Due to individual mobility, the interaction partners of every walker change randomly, hereby introducing an additional, independent source of fluctuations, thus constituting the intrinsic nonequilibrium nature of the temporal dynamics. We employ this paradigmatic model system to discuss how the emergence of order is affected by the motion of individual entities. In particular, we consider both normal diffusive motion and superdiffusion. A non-Hamiltonian field theory including multiplicative noise terms is derived which describes the nonequilibrium dynamics at the macroscale. This theory reveals a defect-mediated transition from incoherence to quasi-long-range order for normal diffusion of oscillators in two dimensions, implying a power-law dependence of all synchronization properties on system size. In contrast, superdiffusive transport suppresses the emergence of topological defects, thereby inducing a continuous synchronization transition to long-range order in two dimensions. These results are consistent with particle-based simulations.

A Synchronous Multi-Body Sensor Platform in a Wireless Body Sensor Network: Design and Implementation

PubMed Central

Gil, Yeongjoon; Wu, Wanqing; Lee, Jungtae

2012-01-01

Background Human life can be further improved if diseases and disorders can be predicted before they become dangerous, by correctly recognizing signals from the human body, so in order to make disease detection more precise, various body-signals need to be measured simultaneously in a synchronized manner. Object This research aims at developing an integrated system for measuring four signals (EEG, ECG, respiration, and PPG) and simultaneously producing synchronous signals on a Wireless Body Sensor Network. Design We designed and implemented a platform for multiple bio-signals using Bluetooth communication. Results First, we developed a prototype board and verified the signals from the sensor platform using frequency responses and quantities. Next, we designed and implemented a lightweight, ultra-compact, low cost, low power-consumption Printed Circuit Board. Conclusion A synchronous multi-body sensor platform is expected to be very useful in telemedicine and emergency rescue scenarios. Furthermore, this system is expected to be able to analyze the mutual effects among body signals. PMID:23112605

Willy Bernal Heredia | NREL

Science.gov Websites

, developing the framework to model whole-campus dynamics to coordinate and synchronize its multiple loads developing the controls for a self-balancing two-wheel electrical vehicle. Education M.S. Electrical

"Trying, Failing, Succeeding, and Trying Again and Again": Perspectives of Teachers of Pupils with Severe Profound Multiple Learning Difficulties

ERIC Educational Resources Information Center

Jones, Phyllis; Riley, Michael W.

2017-01-01

This article explores the perspectives of seven teachers in England who teach pupils with severe profound and multiple learning difficulties about their learning to teach this group of students. Teachers' views were captured through a combination of synchronous and asynchronous online communications. Four themes emerged from teachers' perspectives…

Synchronization transition of a coupled system composed of neurons with coexisting behaviors near a Hopf bifurcation

NASA Astrophysics Data System (ADS)

Jia, Bing

2014-05-01

The coexistence of a resting condition and period-1 firing near a subcritical Hopf bifurcation point, lying between the monostable resting condition and period-1 firing, is often observed in neurons of the central nervous systems. Near such a bifurcation point in the Morris—Lecar (ML) model, the attraction domain of the resting condition decreases while that of the coexisting period-1 firing increases as the bifurcation parameter value increases. With the increase of the coupling strength, and parameter and initial value dependent synchronization transition processes from non-synchronization to compete synchronization are simulated in two coupled ML neurons with coexisting behaviors: one neuron chosen as the resting condition and the other the coexisting period-1 firing. The complete synchronization is either a resting condition or period-1 firing dependent on the initial values of period-1 firing when the bifurcation parameter value is small or middle and is period-1 firing when the parameter value is large. As the bifurcation parameter value increases, the probability of the initial values of a period-1 firing neuron that lead to complete synchronization of period-1 firing increases, while that leading to complete synchronization of the resting condition decreases. It shows that the attraction domain of a coexisting behavior is larger, the probability of initial values leading to complete synchronization of this behavior is higher. The bifurcations of the coupled system are investigated and discussed. The results reveal the complex dynamics of synchronization behaviors of the coupled system composed of neurons with the coexisting resting condition and period-1 firing, and are helpful to further identify the dynamics of the spatiotemporal behaviors of the central nervous system.

Shrimp miR-12 Suppresses White Spot Syndrome Virus Infection by Synchronously Triggering Antiviral Phagocytosis and Apoptosis Pathways

PubMed Central

Shu, Le; Zhang, Xiaobo

2017-01-01

Growing evidence has indicated that the innate immune system can be regulated by microRNAs (miRNAs). However, the mechanism underlying miRNA-mediated simultaneous activation of multiple immune pathways remains unknown. To address this issue, the role of host miR-12 in shrimp (Marsupenaeus japonicus) antiviral immune responses was characterized in the present study. The results indicated that miR-12 participated in virus infection, host phagocytosis, and apoptosis in defense against white spot syndrome virus invasion. miR-12 could simultaneously trigger phagocytosis, apoptosis, and antiviral immunity through the synchronous downregulation of the expression of shrimp genes [PTEN (phosphatase and tensin homolog) and BI-1(transmembrane BAX inhibitor motif containing 6)] and the viral gene (wsv024). Further analysis showed that miR-12 could synchronously mediate the 5′–3′ exonucleolytic degradation of its target mRNAs, and this degradation terminated in the vicinity of the 3′ untranslated region sequence complementary to the seed sequence of miR-12. Therefore, the present study showed novel aspects of the miRNA-mediated simultaneous regulation of multiple immune pathways. PMID:28824612

Phase Zero Contracting Operations-Strategic and Integrative Planning for Contingency and Expeditionary Operations

DTIC Science & Technology

2013-10-01

349–372 Phase Zero Contracting Operations (PZCO) FIGURE 4. CONTRACTING PHASE ZERO: PLAN, EXERCISE, REHEARSE, AND SYNCHRONIZE Note. BPA = Blanket...More Robust Construction Supplies; Oce Equipment; Quality of Life; and Morale, Welfare, and Recreation PO/TO/DO/ BPA Small Purchase Standard Vehicles PO...TO/DO/ BPA Small Purchase Standard Vehicles PO/TO/DO/ BPA Small Purchase Standard Vehicles PO/TO/DO/ BPA Small Purchase Food, Water, Billeting, Hygiene

A dual role of extrinsic noise in coupled synthetic clock cells due to a two-steps synchronization mechanism

NASA Astrophysics Data System (ADS)

Liu, Quan; Yu, FengZhen; Li, ZhiHong; Xiong, Juan; Chen, JianJun; Yi, Ming

2018-07-01

Based on the model describing two coupled synthetic clock cells, the synchronization dynamics under stochastic noise are explored. As extrinsic noise from signal is the predominant form of noise for all gene promoters, we investigate the effects of extrinsic noise original from signal molecule by evaluating the order parameters. It is found that strong noise is beneficial for the synchronization of loose-coupling system, while it destroys the synchronization of tight-coupling system. The underlying mechanisms of these two opposite effects are clarified numerically and theoretically. Our research illustrates that (i) when the coupling strength is small, the noise mainly adjusts the period difference of two cells and the system becomes regular. Theoretical study reveals that the mean effect of noise is like to be influx while signal flow is efflux under such a situation. (ii) With the increment of coupling strength, the cells have the same frequency. It is obvious that the noise mainly changes the phase difference between the two cells and destroys the synchronization of the system. (iii) We also demonstrate that, under certain moderate noise intensities, the noise can induce the synchronization order to be the worst. This nonlinear behavior only can be observed in a very narrow region of coupling strength.

An Autonomous Satellite Time Synchronization System Using Remotely Disciplined VC-OCXOs

PubMed Central

Gu, Xiaobo; Chang, Qing; Glennon, Eamonn P.; Xu, Baoda; Dempseter, Andrew G.; Wang, Dun; Wu, Jiapeng

2015-01-01

An autonomous remote clock control system is proposed to provide time synchronization and frequency syntonization for satellite to satellite or ground to satellite time transfer, with the system comprising on-board voltage controlled oven controlled crystal oscillators (VC-OCXOs) that are disciplined to a remote master atomic clock or oscillator. The synchronization loop aims to provide autonomous operation over extended periods, be widely applicable to a variety of scenarios and robust. A new architecture comprising the use of frequency division duplex (FDD), synchronous time division (STDD) duplex and code division multiple access (CDMA) with a centralized topology is employed. This new design utilizes dual one-way ranging methods to precisely measure the clock error, adopts least square (LS) methods to predict the clock error and employs a third-order phase lock loop (PLL) to generate the voltage control signal. A general functional model for this system is proposed and the error sources and delays that affect the time synchronization are discussed. Related algorithms for estimating and correcting these errors are also proposed. The performance of the proposed system is simulated and guidance for selecting the clock is provided. PMID:26213929

Method and apparatus to debug an integrated circuit chip via synchronous clock stop and scan

DOEpatents

Bellofatto, Ralph E [Ridgefield, CT; Ellavsky, Matthew R [Rochester, MN; Gara, Alan G [Mount Kisco, NY; Giampapa, Mark E [Irvington, NY; Gooding, Thomas M [Rochester, MN; Haring, Rudolf A [Cortlandt Manor, NY; Hehenberger, Lance G [Leander, TX; Ohmacht, Martin [Yorktown Heights, NY

2012-03-20

An apparatus and method for evaluating a state of an electronic or integrated circuit (IC), each IC including one or more processor elements for controlling operations of IC sub-units, and each the IC supporting multiple frequency clock domains. The method comprises: generating a synchronized set of enable signals in correspondence with one or more IC sub-units for starting operation of one or more IC sub-units according to a determined timing configuration; counting, in response to one signal of the synchronized set of enable signals, a number of main processor IC clock cycles; and, upon attaining a desired clock cycle number, generating a stop signal for each unique frequency clock domain to synchronously stop a functional clock for each respective frequency clock domain; and, upon synchronously stopping all on-chip functional clocks on all frequency clock domains in a deterministic fashion, scanning out data values at a desired IC chip state. The apparatus and methodology enables construction of a cycle-by-cycle view of any part of the state of a running IC chip, using a combination of on-chip circuitry and software.

Evaluation of Follicular Synchronization Caused by Estrogen Administration and Its Reproductive Outcome

PubMed Central

Wu, Bi; Shi, Yan; Gong, Xia; Yu, Lin; Chen, Qiuju; Wang, Jian; Sun, Zhaogui

2015-01-01

To evaluate multiple follicular development synchronization after estrogen stimulation in prepubertal mice, follicular responsiveness to gonadotropin superovulation, the prospective reproductive potential and ovarian polycystic ovary syndrome (PCOS)-like symptoms at adulthood, prepubertal mice were intraperitoneally injected with estrogen to establish an animal model with solvent as control. When synchronized tertiary follicles in ovaries, in vitro oocyte maturation and fertilization rates, blastocyst formation rate, developmental potential into offspring by embryo transfer, adult fertility and PCOS-like symptoms, and involved molecular mechanisms were focused, it was found that estrogen stimulation (10μg/gBW) leads to follicular development synchronization at the early tertiary stage in prepubertal mice; reproduction from oocytes to offspring could be realized by means of the artificial reproductive technology though the model mice lost their natural fertility when they were reared to adulthood; and typical symptoms of PCOS, except changes in inflammatory pathways, were not remained up to adulthood. So in conclusion, estrogen can lead to synchronization in follicular development in prepubertal mice, but does not affect reproductive outcome of oocytes, and no typical symptoms of PCOS remained at adulthood despite changes related to inflammation. PMID:26010950

An all-digital receiver for satellite audio broadcasting signals using trellis coded quasi-orthogonal code-division multiplexing

NASA Astrophysics Data System (ADS)

Braun, Walter; Eglin, Peter; Abello, Ricard

1993-02-01

Spread Spectrum Code Division Multiplex is an attractive scheme for the transmission of multiple signals over a satellite transponder. By using orthogonal or quasi-orthogonal spreading codes the interference between the users can be virtually eliminated. However, the acquisition and tracking of the spreading code phase can not take advantage of the code orthogonality since sequential acquisition and Delay-Locked loop tracking depend on correlation with code phases other than the optimal despreading phase. Hence, synchronization is a critical issue in such a system. A demonstration hardware for the verification of the orthogonal CDM synchronization and data transmission concept is being designed and implemented. The system concept, the synchronization scheme, and the implementation are described. The performance of the system is discussed based on computer simulations.

Pathological synchronization in Parkinson's disease: networks, models and treatments.

PubMed

Hammond, Constance; Bergman, Hagai; Brown, Peter

2007-07-01

Parkinson's disease is a common and disabling disorder of movement owing to dopaminergic denervation of the striatum. However, it is still unclear how this denervation perverts normal functioning to cause slowing of voluntary movements. Recent work using tissue slice preparations, animal models and in humans with Parkinson's disease has demonstrated abnormally synchronized oscillatory activity at multiple levels of the basal ganglia-cortical loop. This excessive synchronization correlates with motor deficit, and its suppression by dopaminergic therapies, ablative surgery or deep-brain stimulation might provide the basic mechanism whereby diverse therapeutic strategies ameliorate motor impairment in patients with Parkinson's disease. This review is part of the INMED/TINS special issue, Physiogenic and pathogenic oscillations: the beauty and the beast, based on presentations at the annual INMED/TINS symposium (http://inmednet.com/).

Network control processor for a TDMA system

NASA Astrophysics Data System (ADS)

Suryadevara, Omkarmurthy; Debettencourt, Thomas J.; Shulman, R. B.

Two unique aspects of designing a network control processor (NCP) to monitor and control a demand-assigned, time-division multiple-access (TDMA) network are described. The first involves the implementation of redundancy by synchronizing the databases of two geographically remote NCPs. The two sets of databases are kept in synchronization by collecting data on both systems, transferring databases, sending incremental updates, and the parallel updating of databases. A periodic audit compares the checksums of the databases to ensure synchronization. The second aspect involves the use of a tracking algorithm to dynamically reallocate TDMA frame space. This algorithm detects and tracks current and long-term load changes in the network. When some portions of the network are overloaded while others have excess capacity, the algorithm automatically calculates and implements a new burst time plan.

Optimal synchronization in space

NASA Astrophysics Data System (ADS)

Brede, Markus

2010-02-01

In this Rapid Communication we investigate spatially constrained networks that realize optimal synchronization properties. After arguing that spatial constraints can be imposed by limiting the amount of “wire” available to connect nodes distributed in space, we use numerical optimization methods to construct networks that realize different trade offs between optimal synchronization and spatial constraints. Over a large range of parameters such optimal networks are found to have a link length distribution characterized by power-law tails P(l)∝l-α , with exponents α increasing as the networks become more constrained in space. It is also shown that the optimal networks, which constitute a particular type of small world network, are characterized by the presence of nodes of distinctly larger than average degree around which long-distance links are centered.

Synchronization versus decoherence of neutrino oscillations at intermediate densities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Raffelt, Georg G.; Tamborra, Irene

2010-12-15

We study collective oscillations of a two-flavor neutrino system with arbitrary but fixed density. In the vacuum limit, modes with different energies quickly dephase (kinematical decoherence), whereas in the limit of infinite density they lock to each other (synchronization). For intermediate densities, we find different classes of solutions. There is always a phase transition in the sense of partial synchronization occurring only above a density threshold. For small mixing angles, partial or complete decoherence can be induced by a parametric resonance, introducing a new time scale to the problem, the final outcome depending on the spectrum and mixing angle. Wemore » derive an analytic relation that allows us to calculate the late-time degree of coherence based on the spectrum alone.« less

Performance analysis of the word synchronization properties of the outer code in a TDRSS decoder

NASA Technical Reports Server (NTRS)

Costello, D. J., Jr.; Lin, S.

1984-01-01

A self-synchronizing coding scheme for NASA's TDRSS satellite system is a concatenation of a (2,1,7) inner convolutional code with a (255,223) Reed-Solomon outer code. Both symbol and word synchronization are achieved without requiring that any additional symbols be transmitted. An important parameter which determines the performance of the word sync procedure is the ratio of the decoding failure probability to the undetected error probability. Ideally, the former should be as small as possible compared to the latter when the error correcting capability of the code is exceeded. A computer simulation of a (255,223) Reed-Solomon code as carried out. Results for decoding failure probability and for undetected error probability are tabulated and compared.

Image Capture with Synchronized Multiple-Cameras for Extraction of Accurate Geometries

NASA Astrophysics Data System (ADS)

Koehl, M.; Delacourt, T.; Boutry, C.

2016-06-01

This paper presents a project of recording and modelling tunnels, traffic circles and roads from multiple sensors. The aim is the representation and the accurate 3D modelling of a selection of road infrastructures as dense point clouds in order to extract profiles and metrics from it. Indeed, these models will be used for the sizing of infrastructures in order to simulate exceptional convoy truck routes. The objective is to extract directly from the point clouds the heights, widths and lengths of bridges and tunnels, the diameter of gyrating and to highlight potential obstacles for a convoy. Light, mobile and fast acquisition approaches based on images and videos from a set of synchronized sensors have been tested in order to obtain useable point clouds. The presented solution is based on a combination of multiple low-cost cameras designed on an on-boarded device allowing dynamic captures. The experimental device containing GoPro Hero4 cameras has been set up and used for tests in static or mobile acquisitions. That way, various configurations have been tested by using multiple synchronized cameras. These configurations are discussed in order to highlight the best operational configuration according to the shape of the acquired objects. As the precise calibration of each sensor and its optics are major factors in the process of creation of accurate dense point clouds, and in order to reach the best quality available from such cameras, the estimation of the internal parameters of fisheye lenses of the cameras has been processed. Reference measures were also realized by using a 3D TLS (Faro Focus 3D) to allow the accuracy assessment.

Multiple beam antenna system

NASA Technical Reports Server (NTRS)

Byrnes, P. J.

1972-01-01

Using a computer program which plots beams from antennas located on synchronous satellites onto the earth's surface, several circular and elliptical reflectors were analyzed for pattern coverage. The reflectors considered were circular paraboloid and elliptical shaped.

High-precision multi-node clock network distribution.

PubMed

Chen, Xing; Cui, Yifan; Lu, Xing; Ci, Cheng; Zhang, Xuesong; Liu, Bo; Wu, Hong; Tang, Tingsong; Shi, Kebin; Zhang, Zhigang

2017-10-01

A high precision multi-node clock network for multiple users was built following the precise frequency transmission and time synchronization of 120 km fiber. The network topology adopts a simple star-shaped network structure. The clock signal of a hydrogen maser (synchronized with UTC) was recovered from a 120 km telecommunication fiber link and then was distributed to 4 sub-stations. The fractional frequency instability of all substations is in the level of 10 -15 in a second and the clock offset instability is in sub-ps in root-mean-square average.

Control of Chaos: New Perspectives in Experimental and Theoretical Science. International Journal of Bifurcation and Chaos in Applied Sciences and Engineering. Theme Issue. Part 2, Volume 8, Number 9, September 1998.

DTIC Science & Technology

1998-09-01

discharges in the Onchidium pacemaker neu- "Episodic multiregional cortical coherence at multiple ron," J. Theor. Biol. 156, 269-291. frequencies during...with delay: A model of synchronization of Sepulchre, J. A. & Babloyantz, A. [1993] "Controlling cortical tissue," Neural Comput. 6, 1141-1154...generating circuit of different 363, 411 417. networks," Nature 351, 60-63. Singer, W. [1993] "Synchronization of cortical activity Mpitsos, G. J., Burton, R

Phase-locked patterns of the Kuramoto model on 3-regular graphs

NASA Astrophysics Data System (ADS)

DeVille, Lee; Ermentrout, Bard

2016-09-01

We consider the existence of non-synchronized fixed points to the Kuramoto model defined on sparse networks: specifically, networks where each vertex has degree exactly three. We show that "most" such networks support multiple attracting phase-locked solutions that are not synchronized and study the depth and width of the basins of attraction of these phase-locked solutions. We also show that it is common in "large enough" graphs to find phase-locked solutions where one or more of the links have angle difference greater than π/2.

Phase-locked patterns of the Kuramoto model on 3-regular graphs.

PubMed

DeVille, Lee; Ermentrout, Bard

2016-09-01

We consider the existence of non-synchronized fixed points to the Kuramoto model defined on sparse networks: specifically, networks where each vertex has degree exactly three. We show that "most" such networks support multiple attracting phase-locked solutions that are not synchronized and study the depth and width of the basins of attraction of these phase-locked solutions. We also show that it is common in "large enough" graphs to find phase-locked solutions where one or more of the links have angle difference greater than π/2.

Outcomes of stereotactic body radiotherapy (SBRT) treatment of multiple synchronous and recurrent lung nodules.

PubMed

Owen, Dawn; Olivier, Kenneth R; Mayo, Charles S; Miller, Robert C; Nelson, Kathryn; Bauer, Heather; Brown, Paul D; Park, Sean S; Ma, Daniel J; Garces, Yolanda I

2015-02-18

Stereotactic body radiotherapy (SBRT) is evolving into a standard of care for unresectable lung nodules. Local control has been shown to be in excess of 90% at 3 years. However, some patients present with synchronous lung nodules in the ipsilateral or contralateral lobe or metasynchronous disease. In these cases, patients may receive multiple courses of lung SBRT or a single course for synchronous nodules. The toxicity of such treatment is currently unknown. Between 2006 and 2012, 63 subjects with 128 metasynchronous and synchronous lung nodules were treated at the Mayo Clinic with SBRT. Demographic patient data and dosimetric data regarding SBRT treatments were collected. Acute toxicity (defined as toxicity < 90 days) and late toxicity (defined as toxicity > = 90 days) were reported and graded as per standardized CTCAE 4.0 criteria. Local control, progression free survival and overall survival were also described. The median age of patients treated was 73 years. Sixty five percent were primary or recurrent lung cancers with the remainder metastatic lung nodules of varying histologies. Of 63 patients, 18 had prior high dose external beam radiation to the mediastinum or chest. Dose and fractionation varied but the most common prescriptions were 48 Gy/4 fractions, 54 Gy/3 fractions, and 50 Gy/5 fractions. Only 6 patients demonstrated local recurrence. With a median follow up of 12.6 months, median SBRT specific overall survival and progression free survival were 35.7 months and 10.7 months respectively. Fifty one percent (32/63 patients) experienced acute toxicity, predominantly grade 1 and 2 fatigue. One patient developed acute grade 3 radiation pneumonitis at 75 days. Forty six percent (29/63 patients) developed late effects. Most were grade 1 dyspnea. There was one patient with grade 5 pneumonitis. Multiple courses of SBRT and SBRT delivery after external beam radiotherapy appear to be feasible and safe. Most toxicity was grade 1 and 2 but the risk was approximately 50% for both acute and late effects.

Real-time 3D motion tracking for small animal brain PET

NASA Astrophysics Data System (ADS)

Kyme, A. Z.; Zhou, V. W.; Meikle, S. R.; Fulton, R. R.

2008-05-01

High-resolution positron emission tomography (PET) imaging of conscious, unrestrained laboratory animals presents many challenges. Some form of motion correction will normally be necessary to avoid motion artefacts in the reconstruction. The aim of the current work was to develop and evaluate a motion tracking system potentially suitable for use in small animal PET. This system is based on the commercially available stereo-optical MicronTracker S60 which we have integrated with a Siemens Focus-220 microPET scanner. We present measured performance limits of the tracker and the technical details of our implementation, including calibration and synchronization of the system. A phantom study demonstrating motion tracking and correction was also performed. The system can be calibrated with sub-millimetre accuracy, and small lightweight markers can be constructed to provide accurate 3D motion data. A marked reduction in motion artefacts was demonstrated in the phantom study. The techniques and results described here represent a step towards a practical method for rigid-body motion correction in small animal PET. There is scope to achieve further improvements in the accuracy of synchronization and pose measurements in future work.

Analysis of synchronous digital-modulation schemes for satellite communication

NASA Technical Reports Server (NTRS)

Takhar, G. S.; Gupta, S. C.

1975-01-01

The multipath communication channel for space communications is modeled as a multiplicative channel. This paper discusses the effects of multiplicative channel processes on the symbol error rate for quadrature modulation (QM) digital modulation schemes. An expression for the upper bound on the probability of error is derived and numerically evaluated. The results are compared with those obtained for additive channels.

Detecting synchronization clusters in multivariate time series via coarse-graining of Markov chains.

PubMed

Allefeld, Carsten; Bialonski, Stephan

2007-12-01

Synchronization cluster analysis is an approach to the detection of underlying structures in data sets of multivariate time series, starting from a matrix R of bivariate synchronization indices. A previous method utilized the eigenvectors of R for cluster identification, analogous to several recent attempts at group identification using eigenvectors of the correlation matrix. All of these approaches assumed a one-to-one correspondence of dominant eigenvectors and clusters, which has however been shown to be wrong in important cases. We clarify the usefulness of eigenvalue decomposition for synchronization cluster analysis by translating the problem into the language of stochastic processes, and derive an enhanced clustering method harnessing recent insights from the coarse-graining of finite-state Markov processes. We illustrate the operation of our method using a simulated system of coupled Lorenz oscillators, and we demonstrate its superior performance over the previous approach. Finally we investigate the question of robustness of the algorithm against small sample size, which is important with regard to field applications.

Quantum synchronization of many coupled atoms for an ultranarrow linewidth laser

NASA Astrophysics Data System (ADS)

He, Peiru; Xu, Minghui; Tieri, David; Zhu, Bihui; Rey, Ana Maria; Hazzard, Kaden; Holland, Murray

2014-05-01

We theoretically investigate the effect of quantum synchronization on many coupled two-level atoms acting as high quality oscillators. We show that quantum synchronization - the spontaneous alignment of the phase (of the two-level superposition) between different atoms - provides a potential approach to produce robust atomic coherences and coherent light with ultranarrow linewidth and extreme phase stability. The atoms may be coupled either through their direct dipole-dipole interactions or, as in a superradiant laser, through an optical cavity. We develop a variety of analytic and computational approaches for this problem, including exact open quantum system methods for small systems, semiclassical theories, and approaches that make use of the permutation symmetry of identically coupled ensembles. We investigate the first and second order coherence properties of both the optical and atomic degrees of freedom. We study synchronization in both the steady-state, as well as during the dynamically applied pulse sequences of Rabi and Ramsey interferometry. This work was supported by the DARPA QuASAR program, the NSF, and NIST.

Cascaded clocks measurement and simulation findings

NASA Technical Reports Server (NTRS)

Chislow, Don; Zampetti, George

1994-01-01

This paper will examine aspects related to network synchronization distribution and the cascading of timing elements. Methods of timing distribution have become a much debated topic in standards forums and among network service providers (both domestically and internationally). Essentially these concerns focus on the need to migrate their existing network synchronization plans (and capabilities) to those required for the next generation of transport technologies (namely, the Synchronous Digital Hierarchy (SDH), Synchronous Optical Networks (SONET), and Asynchronous Transfer Mode (ATM). The particular choices for synchronization distribution network architectures are now being evaluated and are demonstrating that they can indeed have a profound effect on the overall service performance levels that will be delivered to the customer. The salient aspects of these concerns reduce to the following: (1) identifying that the devil is in the details of the timing element specifications and the distribution of timing information (i.e., small design choices can have a large performance impact); (2) developing a standardized method of performance verification that will yield unambiguous results; and (3) presentation of those results. Specifically, this will be done for two general cases: an ideal input, and a noisy input to a cascaded chain of slave clocks.

Effect of parameter mismatch on the dynamics of strongly coupled self sustained oscillators.

PubMed

Chakrabarty, Nilaj; Jain, Aditya; Lal, Nijil; Das Gupta, Kantimay; Parmananda, Punit

2017-01-01

In this paper, we present an experimental setup and an associated mathematical model to study the synchronization of two self-sustained, strongly coupled, mechanical oscillators (metronomes). The effects of a small detuning in the internal parameters, namely, damping and frequency, have been studied. Our experimental system is a pair of spring wound mechanical metronomes; coupled by placing them on a common base, free to move along a horizontal direction. We designed a photodiode array based non-contact, non-magnetic position detection system driven by a microcontroller to record the instantaneous angular displacement of each oscillator and the small linear displacement of the base, coupling the two. In our system, the mass of the oscillating pendula forms a significant fraction of the total mass of the system, leading to strong coupling of the oscillators. We modified the internal mechanism of the spring-wound "clockwork" slightly, such that the natural frequency and the internal damping could be independently tuned. Stable synchronized and anti-synchronized states were observed as the difference in the parameters was varied in the experiments. The simulation results showed a rapid increase in the phase difference between the two oscillators beyond a certain threshold of parameter mismatch. Our simple model of the escapement mechanism did not reproduce a complete 180° out of phase state. However, the numerical simulations show that increased mismatch in parameters leads to a synchronized state with a large phase difference.

Collective Phenomena Emerging from the Interactions between Dynamical Processes in Multiplex Networks

NASA Astrophysics Data System (ADS)

Nicosia, Vincenzo; Skardal, Per Sebastian; Arenas, Alex; Latora, Vito

2017-03-01

We introduce a framework to intertwine dynamical processes of different nature, each with its own distinct network topology, using a multilayer network approach. As an example of collective phenomena emerging from the interactions of multiple dynamical processes, we study a model where neural dynamics and nutrient transport are bidirectionally coupled in such a way that the allocation of the transport process at one layer depends on the degree of synchronization at the other layer, and vice versa. We show numerically, and we prove analytically, that the multilayer coupling induces a spontaneous explosive synchronization and a heterogeneous distribution of allocations, otherwise not present in the two systems considered separately. Our framework can find application to other cases where two or more dynamical processes such as synchronization, opinion formation, information diffusion, or disease spreading, are interacting with each other.

Ferromagnetic interaction model of activity level in workplace communication

NASA Astrophysics Data System (ADS)

Akitomi, Tomoaki; Ara, Koji; Watanabe, Jun-ichiro; Yano, Kazuo

2013-03-01

The nature of human-human interaction, specifically, how people synchronize with each other in multiple-participant conversations, is described by a ferromagnetic interaction model of people’s activity levels. We found two microscopic human interaction characteristics from a real-environment face-to-face conversation. The first characteristic is that people quite regularly synchronize their activity level with that of the other participants in a conversation. The second characteristic is that the degree of synchronization increases as the number of participants increases. Based on these microscopic ferromagnetic characteristics, a “conversation activity level” was modeled according to the Ising model. The results of a simulation of activity level based on this model well reproduce macroscopic experimental measurements of activity level. This model will give a new insight into how people interact with each other in a conversation.

System and method for merging clusters of wireless nodes in a wireless network

DOEpatents

Budampati, Ramakrishna S [Maple Grove, MN; Gonia, Patrick S [Maplewood, MN; Kolavennu, Soumitri N [Blaine, MN; Mahasenan, Arun V [Kerala, IN

2012-05-29

A system includes a first cluster having multiple first wireless nodes. One first node is configured to act as a first cluster master, and other first nodes are configured to receive time synchronization information provided by the first cluster master. The system also includes a second cluster having one or more second wireless nodes. One second node is configured to act as a second cluster master, and any other second nodes configured to receive time synchronization information provided by the second cluster master. The system further includes a manager configured to merge the clusters into a combined cluster. One of the nodes is configured to act as a single cluster master for the combined cluster, and the other nodes are configured to receive time synchronization information provided by the single cluster master.

Phase dynamics of oscillating magnetizations coupled via spin pumping

NASA Astrophysics Data System (ADS)

Taniguchi, Tomohiro

2018-05-01

A theoretical formalism is developed to simultaneously solve equation of motion of the magnetizations in two ferromagnets and the spin-pumping induced spin transport equation. Based on the formalism, a coupled motion of the magnetizations in a self-oscillation state is studied. The spin pumping is found to induce an in-phase synchronization of the magnetizations for the oscillation around the easy axis. For an out-of-plane self-oscillation around the hard axis, on the other hand, the spin pumping leads to an in-phase synchronization in a small current region, whereas an antiphase synchronization is excited in a large current region. An analytical theory based on the phase equation reveals that the phase difference between the magnetizations in a steady state depends on the oscillation direction, clockwise or counterclockwise, of the magnetizations.

Dynamic performance of maximum power point tracking circuits using sinusoidal extremum seeking control for photovoltaic generation

NASA Astrophysics Data System (ADS)

Leyva, R.; Artillan, P.; Cabal, C.; Estibals, B.; Alonso, C.

2011-04-01

The article studies the dynamic performance of a family of maximum power point tracking circuits used for photovoltaic generation. It revisits the sinusoidal extremum seeking control (ESC) technique which can be considered as a particular subgroup of the Perturb and Observe algorithms. The sinusoidal ESC technique consists of adding a small sinusoidal disturbance to the input and processing the perturbed output to drive the operating point at its maximum. The output processing involves a synchronous multiplication and a filtering stage. The filter instance determines the dynamic performance of the MPPT based on sinusoidal ESC principle. The approach uses the well-known root-locus method to give insight about damping degree and settlement time of maximum-seeking waveforms. This article shows the transient waveforms in three different filter instances to illustrate the approach. Finally, an experimental prototype corroborates the dynamic analysis.

A digital receiver module with direct data acquisition for magnetic resonance imaging systems.

PubMed

Tang, Weinan; Sun, Hongyu; Wang, Weimin

2012-10-01

A digital receiver module for magnetic resonance imaging (MRI) with detailed hardware implementations is presented. The module is based on a direct sampling scheme using the latest mixed-signal circuit design techniques. A single field-programmable gate array chip is employed to perform software-based digital down conversion for radio frequency signals. The modular architecture of the receiver allows multiple acquisition channels to be implemented on a highly integrated printed circuit board. To maintain the phase coherence of the receiver and the exciter in the context of direct sampling, an effective phase synchronization method was proposed to achieve a phase deviation as small as 0.09°. The performance of the described receiver module was verified in the experiments for both low- and high-field (0.5 T and 1.5 T) MRI scanners and was compared to a modern commercial MRI receiver system.

A Conceptual Design for a Reliable Optical Bus (ROBUS)

NASA Technical Reports Server (NTRS)

Miner, Paul S.; Malekpour, Mahyar; Torres, Wilfredo

2002-01-01

The Scalable Processor-Independent Design for Electromagnetic Resilience (SPIDER) is a new family of fault-tolerant architectures under development at NASA Langley Research Center (LaRC). The SPIDER is a general-purpose computational platform suitable for use in ultra-reliable embedded control applications. The design scales from a small configuration supporting a single aircraft function to a large distributed configuration capable of supporting several functions simultaneously. SPIDER consists of a collection of simplex processing elements communicating via a Reliable Optical Bus (ROBUS). The ROBUS is an ultra-reliable, time-division multiple access broadcast bus with strictly enforced write access (no babbling idiots) providing basic fault-tolerant services using formally verified fault-tolerance protocols including Interactive Consistency (Byzantine Agreement), Internal Clock Synchronization, and Distributed Diagnosis. The conceptual design of the ROBUS is presented in this paper including requirements, topology, protocols, and the block-level design. Verification activities, including the use of formal methods, are also discussed.

Evaluation of Speech Intelligibility and Sound Localization Abilities with Hearing Aids Using Binaural Wireless Technology.

PubMed

Ibrahim, Iman; Parsa, Vijay; Macpherson, Ewan; Cheesman, Margaret

2013-01-02

Wireless synchronization of the digital signal processing (DSP) features between two hearing aids in a bilateral hearing aid fitting is a fairly new technology. This technology is expected to preserve the differences in time and intensity between the two ears by co-ordinating the bilateral DSP features such as multichannel compression, noise reduction, and adaptive directionality. The purpose of this study was to evaluate the benefits of wireless communication as implemented in two commercially available hearing aids. More specifically, this study measured speech intelligibility and sound localization abilities of normal hearing and hearing impaired listeners using bilateral hearing aids with wireless synchronization of multichannel Wide Dynamic Range Compression (WDRC). Twenty subjects participated; 8 had normal hearing and 12 had bilaterally symmetrical sensorineural hearing loss. Each individual completed the Hearing in Noise Test (HINT) and a sound localization test with two types of stimuli. No specific benefit from wireless WDRC synchronization was observed for the HINT; however, hearing impaired listeners had better localization with the wireless synchronization. Binaural wireless technology in hearing aids may improve localization abilities although the possible effect appears to be small at the initial fitting. With adaptation, the hearing aids with synchronized signal processing may lead to an improvement in localization and speech intelligibility. Further research is required to demonstrate the effect of adaptation to the hearing aids with synchronized signal processing on different aspects of auditory performance.

Aggressive intrahepatic therapies for synchronous hepatocellular carcinoma with pulmonary metastasis.

PubMed

Hu, Z; Huang, P; Zhou, Z; Li, W; Xu, J; Xu, K; Wang, J; Zhang, H

2018-06-01

Prognosis of synchronous hepatocellular carcinoma (HCC) patients with pulmonary metastasis (PM) was poor, while aggressive intrahepatic therapies remained controversial. This study aimed to investigate the significance of aggressive intrahepatic therapies for synchronous PM-HCC. Synchronous PM-HCC patients were retrospectively enrolled from Sun Yat-sen Memorial Hospital of Sun Yat-sen University during January 2000 and December 2015. Univariate and multivariate analysis were performed to investigate the prognostic factors. Patients were grouped according to different HCC treatment modalities including liver resection (LR), ablation, transarterial chemoembolization (TACE), systemic therapy (ST, systemic chemotherapy or sorafenib) and supportive care (SC). Case control studies were achieved using propensity score matching (PSM) analysis to further investigate the significance of LR, ablation and TACE. Eighty-one patients were enrolled, and the median overall survival (OS) was 4.5 months. Serum alpha fetal protein (AFP) ≥ 400 ng/ml, multiple HCC lesions and no intrahepatic therapies (LR/Ablation/TACE) were inferior independent prognostic factors. Patients were divided into LR group (n = 9), Ablation/TACE group (n = 24) and ST/SC group (n = 48). After PSM analysis, survival outcome was superior in LR group compared to Ablation/TACE group (19.6 vs. 6.9 months) (p = 0.023) or ST/SC group (19.6 vs. 2.8 months) (p = 0.034), while no significant difference was found between -Ablation/TACE and ST/SC group (5.1 vs. 3.2 months) (p = 0.338). Prognosis of synchronous PM-HCC patients was poor. Serum AFP ≥ 400 ng/ml, multiple HCC lesions and no aggressive intrahepatic therapies were inferior prognostic factors. LR might provide survival benefits in well-selected patients, while the significance of ablation or TACE remained to be further investigated.

Synchrony, compensatory dynamics, and the functional trait basis of phenological diversity in a tropical dry forest tree community: effects of rainfall seasonality

NASA Astrophysics Data System (ADS)

Lasky, Jesse R.; Uriarte, María; Muscarella, Robert

2016-11-01

Interspecific variation in phenology is a key axis of functional diversity, potentially mediating how communities respond to climate change. The diverse drivers of phenology act across multiple temporal scales. For example, abiotic constraints favor synchronous reproduction (positive covariance among species), while biotic interactions can favor synchrony or compensatory dynamics (negative covariance). We used wavelet analyses to examine phenology of community flower and seed production for 45 tree species across multiple temporal scales in a tropical dry forest in Puerto Rico with marked rainfall seasonality. We asked three questions: (1) do species exhibit synchronous or compensatory temporal dynamics in reproduction, (2) do interspecific differences in phenology reflect variable responses to rainfall, and (3) is interspecific variation in phenology and response to a major drought associated with functional traits that mediate responses to moisture? Community-level flowering was synchronized at seasonal scales (˜5-6 mo) and at short scales (˜1 mo, following rainfall). However, seed rain exhibited significant compensatory dynamics at intraseasonal scales (˜3 mo), suggesting interspecific variation in temporal niches. Species with large leaves (associated with sensitivity to water deficit) peaked in reproduction synchronously with the peak of seasonal rainfall (˜5 mo scale). By contrast, species with high wood specific gravity (associated with drought resistance) tended to flower in drier periods. Flowering of tall species and those with large leaves was most tightly linked to intraseasonal (˜2 mo scale) rainfall fluctuations. Although the 2015 drought dramatically reduced community-wide reproduction, functional traits were not associated with the magnitude of species-specific declines. Our results suggest opposing drivers of synchronous versus compensatory dynamics at different temporal scales. Phenology associations with functional traits indicated that distinct strategies for coping with seasonality underlie phenological diversity. Observed drought responses highlight the importance of non-linear community responses to climate. Community phenology exhibits scale-specific patterns highlighting the need for multi-scale approaches to community dynamics.

A reduction for spiking integrate-and-fire network dynamics ranging from homogeneity to synchrony.

PubMed

Zhang, J W; Rangan, A V

2015-04-01

In this paper we provide a general methodology for systematically reducing the dynamics of a class of integrate-and-fire networks down to an augmented 4-dimensional system of ordinary-differential-equations. The class of integrate-and-fire networks we focus on are homogeneously-structured, strongly coupled, and fluctuation-driven. Our reduction succeeds where most current firing-rate and population-dynamics models fail because we account for the emergence of 'multiple-firing-events' involving the semi-synchronous firing of many neurons. These multiple-firing-events are largely responsible for the fluctuations generated by the network and, as a result, our reduction faithfully describes many dynamic regimes ranging from homogeneous to synchronous. Our reduction is based on first principles, and provides an analyzable link between the integrate-and-fire network parameters and the relatively low-dimensional dynamics underlying the 4-dimensional augmented ODE.

Ion Plume Damage in Formation Flight Regimes

NASA Astrophysics Data System (ADS)

Young, Jarred Alexander

This effort examines the potential for damage from plume impingement from an electric propulsion system within spacecraft missions that utilize a formation flight architecture. Specifically, the potential erosion of a structural material (Aluminum) and anti-reflective coatings for solar cell coverglass are explored. Sputter yields for the materials of Aluminum, Magnesium Fluoride, and Indium Tin Oxide are experimentally validated using an electrostatic ion source at energies varying from 500-1500 eV. Erosion depths are analyzed using white-light optical profilometry to measure potential depths up to 1 microm. This erosion data was then utilized to create (or augment) Bohdansky and Yamamura theoretical curve fits for multiple incidence angles to look at theoretical sputter effects within formation flight regimes at multiple formation distances from 50-1000 m. The damage from these electric propulsion plumes is explored throughout multiple orbital conditions from LEO, Sun-Synchronous, and GEO. Factors affecting erosion are: plume density, local geomagnetic field environment and incidence angles of target surfaces. Results from this simulated study show significant erosion with GEO with minor erosion in some LEO and all Sun-Synchronous cases.

Theta synchronizes the activity of medial prefrontal neurons during learning

PubMed Central

Paz, Rony; Bauer, Elizabeth P.; Paré, Denis

2008-01-01

Memory consolidation is thought to involve the gradual transfer of transient hippocampal-dependent traces to distributed neocortical sites via the rhinal cortices. Recently, medial prefrontal (mPFC) neurons were shown to facilitate this process when their activity becomes synchronized. However, the mechanisms underlying this enhanced synchrony remain unclear. Because the hippocampus projects to the mPFC, we tested whether theta oscillations contribute to synchronize mPFC neurons during learning. Thus, we obtained field (LFP) and unit recordings from multiple mPFC sites during the acquisition of a trace-conditioning task, where a visual conditioned stimulus (CS) predicted reward delivery. In quiet waking, the activity of mPFC neurons was modulated by theta oscillations. During conditioning, CS presentation caused an increase in mPFC theta power that augmented as the CS gained predictive value for reward delivery. This increased theta power coincided with a transient theta phase locking at distributed mPFC sites, an effect that was also manifest in the timing of mPFC unit activity. Overall, these results show that theta oscillations contribute to synchronize neuronal activity at distributed mPFC sites, suggesting that the hippocampus, by generating a stronger theta source during learning, can synchronize mPFC activity, in turn facilitating rhinal transfer of its activity to the neocortex. PMID:18612069

Optical slotted circuit switched network: a bandwidth efficient alternative to wavelength-routed network

NASA Astrophysics Data System (ADS)

Li, Yan; Collier, Martin

2007-11-01

Wavelength-routed networks have received enormous attention due to the fact that they are relatively simple to implement and implicitly offer Quality of Service (QoS) guarantees. However, they suffer from a bandwidth inefficiency problem and require complex Routing and Wavelength Assignment (RWA). Most attempts to address the above issues exploit the joint use of WDM and TDM technologies. The resultant TDM-based wavelength-routed networks partition the wavelength bandwidth into fixed-length time slots organized as a fixed-length frame. Multiple connections can thus time-share a wavelength and the grooming of their traffic leads to better bandwidth utilization. The capability of switching in both wavelength and time domains in such networks also mitigates the RWA problem. However, TMD-based wavelength-routed networks work in synchronous mode and strict synchronization among all network nodes is required. Global synchronization for all-optical networks which operate at extremely high speed is technically challenging, and deploying an optical synchronizer for each wavelength involves considerable cost. An Optical Slotted Circuit Switching (OSCS) architecture is proposed in this paper. In an OSCS network, slotted circuits are created to better utilize the wavelength bandwidth than in classic wavelength-routed networks. The operation of the protocol is such as to avoid the need for global synchronization required by TDM-based wavelength-routed networks.

Synchronization of Clocks Through 12 km of Strongly Turbulent Air Over a City.

PubMed

Sinclair, Laura C; Swann, William C; Bergeron, Hugo; Baumann, Esther; Cermak, Michael; Coddington, Ian; Deschênes, Jean-Daniel; Giorgetta, Fabrizio R; Juarez, Juan C; Khader, Isaac; Petrillo, Keith G; Souza, Katherine T; Dennis, Michael L; Newbury, Nathan R

2016-10-15

We demonstrate real-time, femtosecond-level clock synchronization across a low-lying, strongly turbulent, 12-km horizontal air path by optical two-way time transfer. For this long horizontal free-space path, the integrated turbulence extends well into the strong turbulence regime corresponding to multiple scattering with a Rytov variance up to 7 and with the number of signal interruptions exceeding 100 per second. Nevertheless, optical two-way time transfer is used to synchronize a remote clock to a master clock with femtosecond-level agreement and with a relative time deviation dropping as low as a few hundred attoseconds. Synchronization is shown for a remote clock based on either an optical or microwave oscillator and using either tip-tilt or adaptive-optics free-space optical terminals. The performance is unaltered from optical two-way time transfer in weak turbulence across short links. These results confirm that the two-way reciprocity of the free-space time-of-flight is maintained both under strong turbulence and with the use of adaptive optics. The demonstrated robustness of optical two-way time transfer against strong turbulence and its compatibility with adaptive optics is encouraging for future femtosecond clock synchronization over very long distance ground-to-air free-space paths.

Synchronization of Clocks Through 12 km of Strongly Turbulent Air Over a City

PubMed Central

Sinclair, Laura C.; Swann, William C.; Bergeron, Hugo; Baumann, Esther; Cermak, Michael; Coddington, Ian; Deschênes, Jean-Daniel; Giorgetta, Fabrizio R.; Juarez, Juan C.; Khader, Isaac; Petrillo, Keith G.; Souza, Katherine T.; Dennis, Michael L.; Newbury, Nathan R.

2018-01-01

We demonstrate real-time, femtosecond-level clock synchronization across a low-lying, strongly turbulent, 12-km horizontal air path by optical two-way time transfer. For this long horizontal free-space path, the integrated turbulence extends well into the strong turbulence regime corresponding to multiple scattering with a Rytov variance up to 7 and with the number of signal interruptions exceeding 100 per second. Nevertheless, optical two-way time transfer is used to synchronize a remote clock to a master clock with femtosecond-level agreement and with a relative time deviation dropping as low as a few hundred attoseconds. Synchronization is shown for a remote clock based on either an optical or microwave oscillator and using either tip-tilt or adaptive-optics free-space optical terminals. The performance is unaltered from optical two-way time transfer in weak turbulence across short links. These results confirm that the two-way reciprocity of the free-space time-of-flight is maintained both under strong turbulence and with the use of adaptive optics. The demonstrated robustness of optical two-way time transfer against strong turbulence and its compatibility with adaptive optics is encouraging for future femtosecond clock synchronization over very long distance ground-to-air free-space paths. PMID:29348695

Synchronization in human musical rhythms and mutually interacting complex systems

PubMed Central

Hennig, Holger

2014-01-01

Though the music produced by an ensemble is influenced by multiple factors, including musical genre, musician skill, and individual interpretation, rhythmic synchronization is at the foundation of musical interaction. Here, we study the statistical nature of the mutual interaction between two humans synchronizing rhythms. We find that the interbeat intervals of both laypeople and professional musicians exhibit scale-free (power law) cross-correlations. Surprisingly, the next beat to be played by one person is dependent on the entire history of the other person’s interbeat intervals on timescales up to several minutes. To understand this finding, we propose a general stochastic model for mutually interacting complex systems, which suggests a physiologically motivated explanation for the occurrence of scale-free cross-correlations. We show that the observed long-term memory phenomenon in rhythmic synchronization can be imitated by fractal coupling of separately recorded or synthesized audio tracks and thus applied in electronic music. Though this study provides an understanding of fundamental characteristics of timing and synchronization at the interbrain level, the mutually interacting complex systems model may also be applied to study the dynamics of other complex systems where scale-free cross-correlations have been observed, including econophysics, physiological time series, and collective behavior of animal flocks. PMID:25114228

Reusable Client-Side JavaScript Modules for Immersive Web-Based Real-Time Collaborative Neuroimage Visualization.

PubMed

Bernal-Rusiel, Jorge L; Rannou, Nicolas; Gollub, Randy L; Pieper, Steve; Murphy, Shawn; Robertson, Richard; Grant, Patricia E; Pienaar, Rudolph

2017-01-01

In this paper we present a web-based software solution to the problem of implementing real-time collaborative neuroimage visualization. In both clinical and research settings, simple and powerful access to imaging technologies across multiple devices is becoming increasingly useful. Prior technical solutions have used a server-side rendering and push-to-client model wherein only the server has the full image dataset. We propose a rich client solution in which each client has all the data and uses the Google Drive Realtime API for state synchronization. We have developed a small set of reusable client-side object-oriented JavaScript modules that make use of the XTK toolkit, a popular open-source JavaScript library also developed by our team, for the in-browser rendering and visualization of brain image volumes. Efficient realtime communication among the remote instances is achieved by using just a small JSON object, comprising a representation of the XTK image renderers' state, as the Google Drive Realtime collaborative data model. The developed open-source JavaScript modules have already been instantiated in a web-app called MedView , a distributed collaborative neuroimage visualization application that is delivered to the users over the web without requiring the installation of any extra software or browser plugin. This responsive application allows multiple physically distant physicians or researchers to cooperate in real time to reach a diagnosis or scientific conclusion. It also serves as a proof of concept for the capabilities of the presented technological solution.

Wired and Wireless Camera Triggering with Arduino

NASA Astrophysics Data System (ADS)

Kauhanen, H.; Rönnholm, P.

2017-10-01

Synchronous triggering is an important task that allows simultaneous data capture from multiple cameras. Accurate synchronization enables 3D measurements of moving objects or from a moving platform. In this paper, we describe one wired and four wireless variations of Arduino-based low-cost remote trigger systems designed to provide a synchronous trigger signal for industrial cameras. Our wireless systems utilize 315 MHz or 434 MHz frequencies with noise filtering capacitors. In order to validate the synchronization accuracy, we developed a prototype of a rotating trigger detection system (named RoTriDeS). This system is suitable to detect the triggering accuracy of global shutter cameras. As a result, the wired system indicated an 8.91 μs mean triggering time difference between two cameras. Corresponding mean values for the four wireless triggering systems varied between 7.92 and 9.42 μs. Presented values include both camera-based and trigger-based desynchronization. Arduino-based triggering systems appeared to be feasible, and they have the potential to be extended to more complicated triggering systems.

Experimental Evaluation of Processing Time for the Synchronization of XML-Based Business Objects

NASA Astrophysics Data System (ADS)

Ameling, Michael; Wolf, Bernhard; Springer, Thomas; Schill, Alexander

Business objects (BOs) are data containers for complex data structures used in business applications such as Supply Chain Management and Customer Relationship Management. Due to the replication of application logic, multiple copies of BOs are created which have to be synchronized and updated. This is a complex and time consuming task because BOs rigorously vary in their structure according to the distribution, number and size of elements. Since BOs are internally represented as XML documents, the parsing of XML is one major cost factor which has to be considered for minimizing the processing time during synchronization. The prediction of the parsing time for BOs is an significant property for the selection of an efficient synchronization mechanism. In this paper, we present a method to evaluate the influence of the structure of BOs on their parsing time. The results of our experimental evaluation incorporating four different XML parsers examine the dependencies between the distribution of elements and the parsing time. Finally, a general cost model will be validated and simplified according to the results of the experimental setup.

Adaptive oscillator networks with conserved overall coupling: Sequential firing and near-synchronized states

NASA Astrophysics Data System (ADS)

Picallo, Clara B.; Riecke, Hermann

2011-03-01

Motivated by recent observations in neuronal systems we investigate all-to-all networks of nonidentical oscillators with adaptive coupling. The adaptation models spike-timing-dependent plasticity in which the sum of the weights of all incoming links is conserved. We find multiple phase-locked states that fall into two classes: near-synchronized states and splay states. Among the near-synchronized states are states that oscillate with a frequency that depends only very weakly on the coupling strength and is essentially given by the frequency of one of the oscillators, which is, however, neither the fastest nor the slowest oscillator. In sufficiently large networks the adaptive coupling is found to develop effective network topologies dominated by one or two loops. This results in a multitude of stable splay states, which differ in their firing sequences. With increasing coupling strength their frequency increases linearly and the oscillators become less synchronized. The essential features of the two classes of states are captured analytically in perturbation analyses of the extended Kuramoto model used in the simulations.

Driving Sodium/Potassium Pumps with an Oscillating Electric field: Effects on Muscle Fatigue

NASA Astrophysics Data System (ADS)

Lanes, Olivia; Bovyn, Matthew; Chen, Wei

2013-03-01

Dr. Chen has developed a technique called Synchronization Modulation, which has already been proven to be an effective tool in synchronizing and speeding up the sodium/potassium pumps in cell membranes. When synchronized, it is thought that these pumps are more efficient because they require less ATP. We hypothesized that if this was correct, this technique may be used to reduce muscle fatigue. To test our hypothesis, we had multiple test subjects hold a 15 lb weight for as long as they could while isolating the bicep muscle and applying an oscillating electric field. We compared the EMG data we took during these trials to the control, which was done the same way but without applying the electric field. To compare how fatigued subjects were, we did a Fast Fourier Transform on the first and last 10 seconds of each trial to measure the Fatigue Index. Our preliminary results suggest that the Fatigue Index decreased at a slower rate in the trials where the subject held the weight with Synchronization Modulation.

High-Speed Optical Wide-Area Data-Communication Network

NASA Technical Reports Server (NTRS)

Monacos, Steve P.

1994-01-01

Proposed fiber-optic wide-area network (WAN) for digital communication balances input and output flows of data with its internal capacity by routing traffic via dynamically interconnected routing planes. Data transmitted optically through network by wavelength-division multiplexing in synchronous or asynchronous packets. WAN implemented with currently available technology. Network is multiple-ring cyclic shuffle exchange network ensuring traffic reaches its destination with minimum number of hops.

Bioinspired principles for large-scale networked sensor systems: an overview.

PubMed

Jacobsen, Rune Hylsberg; Zhang, Qi; Toftegaard, Thomas Skjødeberg

2011-01-01

Biology has often been used as a source of inspiration in computer science and engineering. Bioinspired principles have found their way into network node design and research due to the appealing analogies between biological systems and large networks of small sensors. This paper provides an overview of bioinspired principles and methods such as swarm intelligence, natural time synchronization, artificial immune system and intercellular information exchange applicable for sensor network design. Bioinspired principles and methods are discussed in the context of routing, clustering, time synchronization, optimal node deployment, localization and security and privacy.

Magnetic switch coupling to synchronize magnetic modulators

DOEpatents

Reed, K.W.; Kiekel, P.

1999-04-27

Apparatus for synchronizing the output pulses from a pair of magnetic switches is disclosed. An electrically conductive loop is provided between the pair of switches with the loop having windings about the core of each of the magnetic switches. The magnetic coupling created by the loop removes voltage and timing variations between the outputs of the two magnetic switches caused by any of a variety of factors. The only remaining variation is a very small fixed timing offset caused by the geometry and length of the loop itself. 13 figs.

Prevalence, effectiveness, and characteristics of pharmacy-based medication synchronization programs.

PubMed

Krumme, Alexis A; Isaman, Danielle L; Stolpe, Samuel F; Dougherty, Samantha; Choudhry, Niteesh K

2016-03-01

The burden of visiting pharmacies to fill medications is a central contributor to nonadherence to maintenance medications. Recently, pharmacies have begun offering services that align prescription fill dates to allow patients to pick up all medications on a single visit. We evaluated the prevalence and structure of synchronization programs and evidence of their impact on adherence and clinical outcomes. Mixed-methods approach consisting of semi-structured interviews, data from surveillance activities, and a systematic literature review. We conducted interviews with opinion leaders from nonprofit advocacy organizations and exemplary synchronization programs. Program prevalence was determined using data from regular surveillance efforts. A literature review included Medline, EMBASE, Google Scholar, and general Internet searches. Synchronization programs exist in approximately 10% of independent, 6% of stand-alone chain, and 11% of retail store pharmacies. The majority of programs include a monthly pharmacist appointment and reminder communication. Programs reported the importance of pharmacist buy-in, technology to track and recruit patients, links to other healthcare services, and flexible solutions for managing costs and communication preferences. Although existing peer-reviewed literature suggests that synchronization improves adherence, more evidence is needed to evaluate its impact on patient-centered outcomes. As medication synchronization programs shift directions and compete for patients and payer resources, it will be more important than ever to rigorously evaluate their ability to improve clinical outcomes while also providing the growing number of patients managing multiple chronic conditions with the highest level of patient engagement and consumer choice.

A Distributed Platform for Global-Scale Agent-Based Models of Disease Transmission

PubMed Central

Parker, Jon; Epstein, Joshua M.

2013-01-01

The Global-Scale Agent Model (GSAM) is presented. The GSAM is a high-performance distributed platform for agent-based epidemic modeling capable of simulating a disease outbreak in a population of several billion agents. It is unprecedented in its scale, its speed, and its use of Java. Solutions to multiple challenges inherent in distributing massive agent-based models are presented. Communication, synchronization, and memory usage are among the topics covered in detail. The memory usage discussion is Java specific. However, the communication and synchronization discussions apply broadly. We provide benchmarks illustrating the GSAM’s speed and scalability. PMID:24465120

[Serrated polyps and their association with synchronous advanced colorectal neoplasia].

PubMed

Urman, Jesús; Gomez, Marta; Basterra, Marta; Mercado, María Del Rosario; Montes, Marta; Gómez Dorronsoro, Marisa; Garaigorta, Maitane; Fraile, María; Rubio, Eva; Aisa, Gregorio; Galbete, Arkaitz

2016-11-01

Large serrated polyps (SP), proximal SP, SP with dysplasia and the presence of multiple sessile serrated adenomas/polyps (SSA/P), which we refer to as SP with increased risk of metachronous lesions (SPIRML), have been associated with an increased risk of advanced colon lesions on follow-up. It is unclear, however, whether SPIRML are also associated with an increased risk of synchronous advanced colorectal neoplasia (ACN). The aim of this study was to estimate the prevalence of SPIRML and to evaluate the association between SPIRML and synchronous ACN. A cross-sectional population-based study in all patients (1,538) with histological diagnosis of SP obtained from colonoscopies, sigmoidoscopies and colonic surgery performed in Navarra Health Service hospitals (Spain) in 2011. Demographic parameters and synchronous colonic lesions (adenomas, advanced adenomas [AA] and ACN) were analyzed. One fourth of the sample (384 patients) presented SPIRML. These were older patients, with a slight predominance of women, and with no differences in body mass index (BMI) compared to patients without SPIRML. In the univariate analysis, patients with SPIRML showed an increased risk of adenoma, AA and ACN. In the multivariate analysis, the SPIRML group had a higher risk of synchronous AA and ACN (odds ratio [OR]: 2.38 [1.77-3.21] and OR: 2.29 [1.72-3.05], respectively); in the case of ACN, this risk was statistically significant in both locations (proximal or distal), with OR slightly higher for the proximal location. Different subtypes of SPIRML had a higher risk of AA and synchronous NA. SPIRML were common in patients with SP, and their presence was associated with an increased risk of synchronous ACN. Copyright © 2016 Elsevier España, S.L.U. y AEEH y AEG. All rights reserved.

Exploring the tolerability of spatiotemporally complex electrical stimulation paradigms.

PubMed

Nelson, Timothy S; Suhr, Courtney L; Lai, Alan; Halliday, Amy J; Freestone, Dean R; McLean, Karen J; Burkitt, Anthony N; Cook, Mark J

2011-10-01

A modified cortical stimulation model was used to investigate the effects of varying the synchronicity and periodicity of electrical stimuli delivered to multiple pairs of electrodes on seizure initiation. In this model, electrical stimulation of the motor cortex of rats, along four pairs of a microwire electrode array, results in an observable seizure with quantifiable electrographic duration and behavioural severity. Periodic stimuli had a constant inter-stimulus intervals across the two-second stimulus duration, whilst synchronous stimuli consisted of singular biphasic, bipolar pulses delivered to the four pairs of electrodes at precisely the same time for the entire two second stimulation period. In this way four combinations of stimulation were possible; periodic/synchronous (P/S), periodic/asynchronous (P/As), aperiodic/synchronous (Ap/S) and aperiodic/asynchronous (Ap/As). All stimulation types were designed with equal pulse width, current intensity and mean frequency of stimulation (60 Hz), standardizing net charge transfer. It was expected that the periodicity of the stimulus would be the primary determinant of seizure initiation and therefore severity and electrographic duration. However, the results showed that significant differences in both severity and duration only occurred when the synchronicity was altered. For periodic stimuli, synchronous delivery increased median seizure duration from 5 s to 13 s and increased median Racine severity from 1 to 3. In the aperiodic case, synchronous stimulus delivery increased median duration from 5.5 s to 11s and resulted in seizures of median severity 3 vs. 0 in the asynchronous case. These findings may have implications for the design of future neurostimulation waveform designs as higher numbers of electrodes and stimulator output channels become available in next generation implants. Copyright © 2011 Elsevier B.V. All rights reserved.

Synchronous volvulus of the sigmoid colon and caecum, a very rare cause of large bowel obstruction.

PubMed

Islam, Shariful; Hosein, Devin; Bheem, Vinoo; Dan, Dilip

2016-10-14

Colonic volvulus usually occurs as a single event that can affect various parts of the colon. The usual sites affected being the sigmoid colon (75%) and the caecum (22%). The phenomenon of multiple sites simultaneously undergoing volvulus is an extremely rare occurrence. Synchronous double colonic volvulus is extremely rare and to the best of our knowledge, this is the 4th reported case of simultaneous sigmoid and caecal volvulus in the English literature. The clinical presentation and the radiological findings are that of large bowel obstruction. Classic radiological findings may not be present or may be overlooked due to its rarity. Treatment of this condition is early surgical intervention to prevent the sequalae of a colonic volvulus and its associated mortality. We report a case of an 80-year-old man with synchronous volvulus of the sigmoid colon and caecum. 2016 BMJ Publishing Group Ltd.

Optimal Implementations for Reliable Circadian Clocks

NASA Astrophysics Data System (ADS)

Hasegawa, Yoshihiko; Arita, Masanori

2014-09-01

Circadian rhythms are acquired through evolution to increase the chances for survival through synchronizing with the daylight cycle. Reliable synchronization is realized through two trade-off properties: regularity to keep time precisely, and entrainability to synchronize the internal time with daylight. We find by using a phase model with multiple inputs that achieving the maximal limit of regularity and entrainability entails many inherent features of the circadian mechanism. At the molecular level, we demonstrate the role sharing of two light inputs, phase advance and delay, as is well observed in mammals. At the behavioral level, the optimal phase-response curve inevitably contains a dead zone, a time during which light pulses neither advance nor delay the clock. We reproduce the results of phase-controlling experiments entrained by two types of periodic light pulses. Our results indicate that circadian clocks are designed optimally for reliable clockwork through evolution.

Rapid learning in visual cortical networks.

PubMed

Wang, Ye; Dragoi, Valentin

2015-08-26

Although changes in brain activity during learning have been extensively examined at the single neuron level, the coding strategies employed by cell populations remain mysterious. We examined cell populations in macaque area V4 during a rapid form of perceptual learning that emerges within tens of minutes. Multiple single units and LFP responses were recorded as monkeys improved their performance in an image discrimination task. We show that the increase in behavioral performance during learning is predicted by a tight coordination of spike timing with local population activity. More spike-LFP theta synchronization is correlated with higher learning performance, while high-frequency synchronization is unrelated with changes in performance, but these changes were absent once learning had stabilized and stimuli became familiar, or in the absence of learning. These findings reveal a novel mechanism of plasticity in visual cortex by which elevated low-frequency synchronization between individual neurons and local population activity accompanies the improvement in performance during learning.

Analytical minimization of synchronicity errors in stochastic identification

NASA Astrophysics Data System (ADS)

Bernal, D.

2018-01-01

An approach to minimize error due to synchronicity faults in stochastic system identification is presented. The scheme is based on shifting the time domain signals so the phases of the fundamental eigenvector estimated from the spectral density are zero. A threshold on the mean of the amplitude-weighted absolute value of these phases, above which signal shifting is deemed justified, is derived and found to be proportional to the first mode damping ratio. It is shown that synchronicity faults do not map precisely to phasor multiplications in subspace identification and that the accuracy of spectral density estimated eigenvectors, for inputs with arbitrary spectral density, decrease with increasing mode number. Selection of a corrective strategy based on signal alignment, instead of eigenvector adjustment using phasors, is shown to be the product of the foregoing observations. Simulations that include noise and non-classical damping suggest that the scheme can provide sufficient accuracy to be of practical value.

Theta coupling between V4 and prefrontal cortex predicts visual short-term memory performance.

PubMed

Liebe, Stefanie; Hoerzer, Gregor M; Logothetis, Nikos K; Rainer, Gregor

2012-01-29

Short-term memory requires communication between multiple brain regions that collectively mediate the encoding and maintenance of sensory information. It has been suggested that oscillatory synchronization underlies intercortical communication. Yet, whether and how distant cortical areas cooperate during visual memory remains elusive. We examined neural interactions between visual area V4 and the lateral prefrontal cortex using simultaneous local field potential (LFP) recordings and single-unit activity (SUA) in monkeys performing a visual short-term memory task. During the memory period, we observed enhanced between-area phase synchronization in theta frequencies (3-9 Hz) of LFPs together with elevated phase locking of SUA to theta oscillations across regions. In addition, we found that the strength of intercortical locking was predictive of the animals' behavioral performance. This suggests that theta-band synchronization coordinates action potential communication between V4 and prefrontal cortex that may contribute to the maintenance of visual short-term memories.

Sleep: A synchrony of cell activity-driven small network states

PubMed Central

Krueger, James M.; Huang, Yanhua; Rector, David M.; Buysse, Daniel J.

2013-01-01

We posit a bottom-up sleep regulatory paradigm in which state changes are initiated within small networks as a consequence of local cell activity. Bottom-up regulatory mechanisms are prevalent throughout nature, occurring in vastly different systems and levels of organization. Synchronization of state without top-down regulation is a fundamental property of large collections of small semi-autonomous entities. We posit that such synchronization mechanisms are sufficient and necessary for whole organism sleep onset. Within brain we posit that small networks of highly interconnected neurons and glia, e.g. cortical columns, are semi-autonomous units oscillating between sleep-like and wake-like states. We review evidence showing that cells, small networks, and regional areas of brain share sleep-like properties with whole animal sleep. A testable hypothesis focused on how sleep is initiated within local networks is presented. We posit that the release of cell activity-dependent molecules, such as ATP and nitric oxide, into the extracellular space initiates state changes within the local networks where they are produced. We review mechanisms of ATP induction of sleep regulatory substances (SRS) and their actions on receptor trafficking. Finally, we provide an example of how such local metabolic and state changes provide mechanistic explanations for clinical conditions such as insomnia. PMID:23651209

Use of Synchronized Phasor Measurements for Model Validation in ERCOT

NASA Astrophysics Data System (ADS)

Nuthalapati, Sarma; Chen, Jian; Shrestha, Prakash; Huang, Shun-Hsien; Adams, John; Obadina, Diran; Mortensen, Tim; Blevins, Bill

2013-05-01

This paper discusses experiences in the use of synchronized phasor measurement technology in Electric Reliability Council of Texas (ERCOT) interconnection, USA. Implementation of synchronized phasor measurement technology in the region is a collaborative effort involving ERCOT, ONCOR, AEP, SHARYLAND, EPG, CCET, and UT-Arlington. As several phasor measurement units (PMU) have been installed in ERCOT grid in recent years, phasor data with the resolution of 30 samples per second is being used to monitor power system status and record system events. Post-event analyses using recorded phasor data have successfully verified ERCOT dynamic stability simulation studies. Real time monitoring software "RTDMS"® enables ERCOT to analyze small signal stability conditions by monitoring the phase angles and oscillations. The recorded phasor data enables ERCOT to validate the existing dynamic models of conventional and/or wind generator.

Demonstration of intercontinental DSN clock synchronization by VLBI

NASA Technical Reports Server (NTRS)

Hurd, W. J.

1973-01-01

The prototype system for Deep Space Network clock synchronization by VLBI has been demonstrated to operate successfully over intercontinental baselines in a series of experiments between Deep Space Stations at Madrid, Spain, and Goldstone, California. As predicted by analysis and short baseline demonstration, the system achieves reliable synchronization between 26m and 64m antenna stations with 17 and 37K nominal system temperatures using under one million bits of data from each station. Semi-real-time operation is feasible since this small amount of data can be transmitted to JPL and processed within minutes. The system resolution is 50 to 400ns, depending on the amount of data processed and the source intensity. The accuracy is believed to be comparable to the resolution, although it could be independently confirmed to only about 5 microseconds using LORAN C.

Advanced multiple access concepts in mobile satellite systems

NASA Technical Reports Server (NTRS)

Ananasso, Fulvio

1990-01-01

Some multiple access strategies for Mobile Satellite Systems (MSS) are discussed. These strategies were investigated in the context of three separate studies conducted for the International Maritime Satellite Organization (INMARSAT) and the European Space Agency (ESA). Satellite-Switched Frequency Division Multiple Access (SS-FDMA), Code Division Multiple Access (CDMA), and Frequency-Addressable Beam architectures are addressed, discussing both system and technology aspects and outlining advantages and drawbacks of either solution with associated relevant hardware issues. An attempt is made to compare the considered option from the standpoint of user terminal/space segment complexity, synchronization requirements, spectral efficiency, and interference rejection.

High speed x-ray beam chopper

DOEpatents

McPherson, Armon; Mills, Dennis M.

2002-01-01

A fast, economical, and compact x-ray beam chopper with a small mass and a small moment of inertia whose rotation can be synchronized and phase locked to an electronic signal from an x-ray source and be monitored by a light beam is disclosed. X-ray bursts shorter than 2.5 microseconds have been produced with a jitter time of less than 3 ns.

Trends in abundance of collared lemmings near Cape Churchill, Manitoba, Canada

USGS Publications Warehouse

Reiter, M.E.; Andersen, D.E.

2008-01-01

Regular, multiannual cycles observed in the population abundance of small mammals in many arctic and subarctic ecosystems have stimulated substantial research, particularly among population ecologists. Hypotheses of mechanisms generating regular cycles include predator-prey interactions, limitation of food resources, and migration or dispersal, as well as abiotic factors such as cyclic climatic variation and environmental stochasticity. In 2004 and 2005, we used indirect methods to estimate trends in population size of Richardson's collared lemmings (Dicrostonyx richardsoni) retrospectively, and evaluated the extent of synchrony between lemming populations at 2 coastal tundra study areas separated by approximately 60 km near Cape Churchill, Manitoba, Canada. We collected scars on willow plants (Salix) resulting from lemming feeding. Ages of scars ranged from 0 to 13 years at both study areas. Scar-age frequency appeared cyclic and we used nonlinear Poisson regression to model the observed scar-age frequency. Lemming populations cycled with 2.8-year periodicity and the phase of the cycle was synchronous between the 2 study areas. We suggest that our approach could be applied in multiple settings and may provide the most efficient way to gather data on small mammals across both space and time in a diversity of landscapes. ?? 2008 American Society of Mammalogists.

The scale-dependent market trend: Empirical evidences using the lagged DFA method

NASA Astrophysics Data System (ADS)

Li, Daye; Kou, Zhun; Sun, Qiankun

2015-09-01

In this paper we make an empirical research and test the efficiency of 44 important market indexes in multiple scales. A modified method based on the lagged detrended fluctuation analysis is utilized to maximize the information of long-term correlations from the non-zero lags and keep the margin of errors small when measuring the local Hurst exponent. Our empirical result illustrates that a common pattern can be found in the majority of the measured market indexes which tend to be persistent (with the local Hurst exponent > 0.5) in the small time scale, whereas it displays significant anti-persistent characteristics in large time scales. Moreover, not only the stock markets but also the foreign exchange markets share this pattern. Considering that the exchange markets are only weakly synchronized with the economic cycles, it can be concluded that the economic cycles can cause anti-persistence in the large time scale but there are also other factors at work. The empirical result supports the view that financial markets are multi-fractal and it indicates that deviations from efficiency and the type of model to describe the trend of market price are dependent on the forecasting horizon.

Lung vasculature imaging using speckle variance optical coherence tomography

NASA Astrophysics Data System (ADS)

Cua, Michelle; Lee, Anthony M. D.; Lane, Pierre M.; McWilliams, Annette; Shaipanich, Tawimas; MacAulay, Calum E.; Yang, Victor X. D.; Lam, Stephen

2012-02-01

Architectural changes in and remodeling of the bronchial and pulmonary vasculature are important pathways in diseases such as asthma, chronic obstructive pulmonary disease (COPD), and lung cancer. However, there is a lack of methods that can find and examine small bronchial vasculature in vivo. Structural lung airway imaging using optical coherence tomography (OCT) has previously been shown to be of great utility in examining bronchial lesions during lung cancer screening under the guidance of autofluorescence bronchoscopy. Using a fiber optic endoscopic OCT probe, we acquire OCT images from in vivo human subjects. The side-looking, circumferentially-scanning probe is inserted down the instrument channel of a standard bronchoscope and manually guided to the imaging location. Multiple images are collected with the probe spinning proximally at 100Hz. Due to friction, the distal end of the probe does not spin perfectly synchronous with the proximal end, resulting in non-uniform rotational distortion (NURD) of the images. First, we apply a correction algorithm to remove NURD. We then use a speckle variance algorithm to identify vasculature. The initial data show a vascaulture density in small human airways similar to what would be expected.

Identical synchronization of nonidentical oscillators: when only birds of different feathers flock together

NASA Astrophysics Data System (ADS)

Zhang, Yuanzhao; Motter, Adilson E.

2018-01-01

An outstanding problem in the study of networks of heterogeneous dynamical units concerns the development of rigorous methods to probe the stability of synchronous states when the differences between the units are not small. Here, we address this problem by presenting a generalization of the master stability formalism that can be applied to heterogeneous oscillators with large mismatches. Our approach is based on the simultaneous block diagonalization of the matrix terms in the variational equation, and it leads to dimension reduction that simplifies the original equation significantly. This new formalism allows the systematic investigation of scenarios in which the oscillators need to be nonidentical in order to reach an identical state, where all oscillators are completely synchronized. In the case of networks of identically coupled oscillators, this corresponds to breaking the symmetry of the system as a means to preserve the symmetry of the dynamical state— a recently discovered effect termed asymmetry-induced synchronization (AISync). Our framework enables us to identify communication delay as a new and potentially common mechanism giving rise to AISync, which we demonstrate using networks of delay-coupled Stuart-Landau oscillators. The results also have potential implications for control, as they reveal oscillator heterogeneity as an attribute that may be manipulated to enhance the stability of synchronous states.

Drosophila Ionotropic Receptor 25a mediates circadian clock resetting by temperature.

PubMed

Chen, Chenghao; Buhl, Edgar; Xu, Min; Croset, Vincent; Rees, Johanna S; Lilley, Kathryn S; Benton, Richard; Hodge, James J L; Stanewsky, Ralf

2015-11-26

Circadian clocks are endogenous timers adjusting behaviour and physiology with the solar day. Synchronized circadian clocks improve fitness and are crucial for our physical and mental well-being. Visual and non-visual photoreceptors are responsible for synchronizing circadian clocks to light, but clock-resetting is also achieved by alternating day and night temperatures with only 2-4 °C difference. This temperature sensitivity is remarkable considering that the circadian clock period (~24 h) is largely independent of surrounding ambient temperatures. Here we show that Drosophila Ionotropic Receptor 25a (IR25a) is required for behavioural synchronization to low-amplitude temperature cycles. This channel is expressed in sensory neurons of internal stretch receptors previously implicated in temperature synchronization of the circadian clock. IR25a is required for temperature-synchronized clock protein oscillations in subsets of central clock neurons. Extracellular leg nerve recordings reveal temperature- and IR25a-dependent sensory responses, and IR25a misexpression confers temperature-dependent firing of heterologous neurons. We propose that IR25a is part of an input pathway to the circadian clock that detects small temperature differences. This pathway operates in the absence of known 'hot' and 'cold' sensors in the Drosophila antenna, revealing the existence of novel periphery-to-brain temperature signalling channels.

Synchronization of Mammalian Cells and Nuclei by Centrifugal Elutriation.

PubMed

Banfalvi, Gaspar

2017-01-01

Synchronized populations of large numbers of cells can be obtained by centrifugal elutriation on the basis of sedimentation properties of small round particles, with minimal perturbation of cellular functions. The physical characteristics of cell size and sedimentation velocity are operative in the technique of centrifugal elutriation also known as counterstreaming centrifugation. The elutriator is an advanced device for increasing the sedimentation rate to yield enhanced resolution of cell separation. A random population of cells is introduced into the elutriation chamber of an elutriator rotor running in a specially designed centrifuge. By increasing step-by-step the flow rate of the elutriation fluid, successive populations of relatively homogeneous cell size can be removed from the elutriation chamber and used as synchronized subpopulations. For cell synchronization by centrifugal elutriation, early log S phase cell populations are most suitable where most of the cells are in G1 and S phase (>80 %). Apoptotic cells can be found in the early elutriation fractions belonging to the sub-Go window. Protocols for the synchronization of nuclei of murine pre-B cells and high-resolution centrifugal elutriation of CHO cells are given. The verification of purity and cell cycle positions of cells in elutriated fractions includes the measurement of DNA synthesis by [ 3 H]-thymidine incorporation and DNA content by propidium iodide flow cytometry.

Partial synchronization in networks of non-linearly coupled oscillators: The Deserter Hubs Model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Freitas, Celso, E-mail: cbnfreitas@gmail.com; Macau, Elbert, E-mail: elbert.macau@inpe.br; Pikovsky, Arkady, E-mail: pikovsky@uni-potsdam.de

2015-04-15

We study the Deserter Hubs Model: a Kuramoto-like model of coupled identical phase oscillators on a network, where attractive and repulsive couplings are balanced dynamically due to nonlinearity of interactions. Under weak force, an oscillator tends to follow the phase of its neighbors, but if an oscillator is compelled to follow its peers by a sufficient large number of cohesive neighbors, then it actually starts to act in the opposite manner, i.e., in anti-phase with the majority. Analytic results yield that if the repulsion parameter is small enough in comparison with the degree of the maximum hub, then the fullmore » synchronization state is locally stable. Numerical experiments are performed to explore the model beyond this threshold, where the overall cohesion is lost. We report in detail partially synchronous dynamical regimes, like stationary phase-locking, multistability, periodic and chaotic states. Via statistical analysis of different network organizations like tree, scale-free, and random ones, we found a measure allowing one to predict relative abundance of partially synchronous stationary states in comparison to time-dependent ones.« less

The Functional Role of Neural Oscillations in Non-Verbal Emotional Communication

PubMed Central

Symons, Ashley E.; El-Deredy, Wael; Schwartze, Michael; Kotz, Sonja A.

2016-01-01

Effective interpersonal communication depends on the ability to perceive and interpret nonverbal emotional expressions from multiple sensory modalities. Current theoretical models propose that visual and auditory emotion perception involves a network of brain regions including the primary sensory cortices, the superior temporal sulcus (STS), and orbitofrontal cortex (OFC). However, relatively little is known about how the dynamic interplay between these regions gives rise to the perception of emotions. In recent years, there has been increasing recognition of the importance of neural oscillations in mediating neural communication within and between functional neural networks. Here we review studies investigating changes in oscillatory activity during the perception of visual, auditory, and audiovisual emotional expressions, and aim to characterize the functional role of neural oscillations in nonverbal emotion perception. Findings from the reviewed literature suggest that theta band oscillations most consistently differentiate between emotional and neutral expressions. While early theta synchronization appears to reflect the initial encoding of emotionally salient sensory information, later fronto-central theta synchronization may reflect the further integration of sensory information with internal representations. Additionally, gamma synchronization reflects facilitated sensory binding of emotional expressions within regions such as the OFC, STS, and, potentially, the amygdala. However, the evidence is more ambiguous when it comes to the role of oscillations within the alpha and beta frequencies, which vary as a function of modality (or modalities), presence or absence of predictive information, and attentional or task demands. Thus, the synchronization of neural oscillations within specific frequency bands mediates the rapid detection, integration, and evaluation of emotional expressions. Moreover, the functional coupling of oscillatory activity across multiples frequency bands supports a predictive coding model of multisensory emotion perception in which emotional facial and body expressions facilitate the processing of emotional vocalizations. PMID:27252638

The Functional Role of Neural Oscillations in Non-Verbal Emotional Communication.

PubMed

Symons, Ashley E; El-Deredy, Wael; Schwartze, Michael; Kotz, Sonja A

2016-01-01

Effective interpersonal communication depends on the ability to perceive and interpret nonverbal emotional expressions from multiple sensory modalities. Current theoretical models propose that visual and auditory emotion perception involves a network of brain regions including the primary sensory cortices, the superior temporal sulcus (STS), and orbitofrontal cortex (OFC). However, relatively little is known about how the dynamic interplay between these regions gives rise to the perception of emotions. In recent years, there has been increasing recognition of the importance of neural oscillations in mediating neural communication within and between functional neural networks. Here we review studies investigating changes in oscillatory activity during the perception of visual, auditory, and audiovisual emotional expressions, and aim to characterize the functional role of neural oscillations in nonverbal emotion perception. Findings from the reviewed literature suggest that theta band oscillations most consistently differentiate between emotional and neutral expressions. While early theta synchronization appears to reflect the initial encoding of emotionally salient sensory information, later fronto-central theta synchronization may reflect the further integration of sensory information with internal representations. Additionally, gamma synchronization reflects facilitated sensory binding of emotional expressions within regions such as the OFC, STS, and, potentially, the amygdala. However, the evidence is more ambiguous when it comes to the role of oscillations within the alpha and beta frequencies, which vary as a function of modality (or modalities), presence or absence of predictive information, and attentional or task demands. Thus, the synchronization of neural oscillations within specific frequency bands mediates the rapid detection, integration, and evaluation of emotional expressions. Moreover, the functional coupling of oscillatory activity across multiples frequency bands supports a predictive coding model of multisensory emotion perception in which emotional facial and body expressions facilitate the processing of emotional vocalizations.

Acceleration of neutrons in a scheme of a tautochronous mathematical pendulum (physical principles)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rivlin, Lev A

We consider the physical principles of neutron acceleration through a multiple synchronous interaction with a gradient rf magnetic field in a scheme of a tautochronous mathematical pendulum. (laser applications and other aspects of quantum electronics)

Evaluation of Speech Intelligibility and Sound Localization Abilities with Hearing Aids Using Binaural Wireless Technology

PubMed Central

Ibrahim, Iman; Parsa, Vijay; Macpherson, Ewan; Cheesman, Margaret

2012-01-01

Wireless synchronization of the digital signal processing (DSP) features between two hearing aids in a bilateral hearing aid fitting is a fairly new technology. This technology is expected to preserve the differences in time and intensity between the two ears by co-ordinating the bilateral DSP features such as multichannel compression, noise reduction, and adaptive directionality. The purpose of this study was to evaluate the benefits of wireless communication as implemented in two commercially available hearing aids. More specifically, this study measured speech intelligibility and sound localization abilities of normal hearing and hearing impaired listeners using bilateral hearing aids with wireless synchronization of multichannel Wide Dynamic Range Compression (WDRC). Twenty subjects participated; 8 had normal hearing and 12 had bilaterally symmetrical sensorineural hearing loss. Each individual completed the Hearing in Noise Test (HINT) and a sound localization test with two types of stimuli. No specific benefit from wireless WDRC synchronization was observed for the HINT; however, hearing impaired listeners had better localization with the wireless synchronization. Binaural wireless technology in hearing aids may improve localization abilities although the possible effect appears to be small at the initial fitting. With adaptation, the hearing aids with synchronized signal processing may lead to an improvement in localization and speech intelligibility. Further research is required to demonstrate the effect of adaptation to the hearing aids with synchronized signal processing on different aspects of auditory performance. PMID:26557339

Calcium waves in a grid of clustered channels with synchronous IP3 binding and unbinding.

PubMed

Rückl, M; Rüdiger, S

2016-11-01

Calcium signals in cells occur at multiple spatial scales and variable temporal duration. However, a physical explanation for transitions between long-lasting global oscillations and localized short-term elevations (puffs) of cytoplasmic Ca 2+ is still lacking. Here we introduce a phenomenological, coarse-grained model for the calcium variable, which is represented by ordinary differential equations. Due to its small number of parameters, and its simplicity, this model allows us to numerically study the interplay of multi-scale calcium concentrations with stochastic ion channel gating dynamics even in larger systems. We apply this model to a single cluster of inositol trisphosphate (IP 3 ) receptor channels and find further evidence for the results presented in earlier work: a single cluster may be capable of producing different calcium release types, where long-lasting events are accompanied by unbinding of IP 3 from the receptor (Rückl et al., PLoS Comput. Biol. 11, e1003965 (2015)). Finally, we show the practicability of the model in a grid of 64 clusters which is computationally intractable with previous high-resolution models. Here long-lasting events can lead to synchronized oscillations and waves, while short events stay localized. The frequency of calcium releases as well as their coherence can thereby be regulated by the amplitude of IP 3 stimulation. Finally the model allows for a new explanation of oscillating [IP 3 ], which is not based on metabolic production and degradation of IP 3 .

Objective models of EMG signals for cyclic processes such as a human gait

NASA Astrophysics Data System (ADS)

Babska, Luiza; Selegrat, Monika; Dusza, Jacek J.

2016-09-01

EMG signals are small potentials appearing at the surface of human skin during muscle work. They arise due to changes in the physiological state of cell membranes in the muscle fibers. They are characterized by a relatively low frequency range (500 Hz) and a low amplitude signal (of the order of μV), making it difficult to record. Raw EMG signal is inherently random shape. However we can distinguish certain features related to the activation of the muscles of a deterministic or quasi-deterministic associated with the movement and its parametric description. Objective models of EMG signals were created on the base of actual data obtained from the VICON system installed at the University of Physical Education in Warsaw. The object of research (healthy woman) moved repeatedly after a fixed track. On her body 35 reflective markers to record the gait kinematics and 8 electrodes to record EMG signals were placed. We obtained research data included more than 1,000 EMG signals synchronized with the phases of gait. Test result of the work is an algorithm for obtaining the average EMG signal received from the multiple registration gait cycles carried out in the same reproducible conditions. The method described in the article is essentially a pre-finding measurement data from the two quasi-synchronous signals at different sampling frequencies for further processing. This signal is characterized by a significant reduction of high frequency noise and emphasis on the specific characteristics of individual records found in muscle activity.

Dynamical responses to external stimuli for both cases of excitatory and inhibitory synchronization in a complex neuronal network.

PubMed

Kim, Sang-Yoon; Lim, Woochang

2017-10-01

For studying how dynamical responses to external stimuli depend on the synaptic-coupling type, we consider two types of excitatory and inhibitory synchronization (i.e., synchronization via synaptic excitation and inhibition) in complex small-world networks of excitatory regular spiking (RS) pyramidal neurons and inhibitory fast spiking (FS) interneurons. For both cases of excitatory and inhibitory synchronization, effects of synaptic couplings on dynamical responses to external time-periodic stimuli S ( t ) (applied to a fraction of neurons) are investigated by varying the driving amplitude A of S ( t ). Stimulated neurons are phase-locked to external stimuli for both cases of excitatory and inhibitory couplings. On the other hand, the stimulation effect on non-stimulated neurons depends on the type of synaptic coupling. The external stimulus S ( t ) makes a constructive effect on excitatory non-stimulated RS neurons (i.e., it causes external phase lockings in the non-stimulated sub-population), while S ( t ) makes a destructive effect on inhibitory non-stimulated FS interneurons (i.e., it breaks up original inhibitory synchronization in the non-stimulated sub-population). As results of these different effects of S ( t ), the type and degree of dynamical response (e.g., synchronization enhancement or suppression), characterized by the dynamical response factor [Formula: see text] (given by the ratio of synchronization degree in the presence and absence of stimulus), are found to vary in a distinctly different way, depending on the synaptic-coupling type. Furthermore, we also measure the matching degree between the dynamics of the two sub-populations of stimulated and non-stimulated neurons in terms of a "cross-correlation" measure [Formula: see text]. With increasing A , based on [Formula: see text], we discuss the cross-correlations between the two sub-populations, affecting the dynamical responses to S ( t ).

Secular motion around synchronously orbiting planetary satellites.

PubMed

Lara, Martin; San-Juan, Juan F; Ferrer, Sebastián

2005-12-01

We investigate the secular motion of a spacecraft around the natural satellite of a planet. The satellite rotates synchronously with its mean motion around the planet. Our model takes into account the gravitational potential of the satellite up to the second order, and the third-body perturbation in Hill's approximation. Close to the satellite, the ratio of rotation rate of the satellite to mean motion of the orbiter is small. When considering this ratio as a small parameter, the Coriolis effect is a first-order perturbation, while the third-body tidal attraction, the ellipticity effect, and the oblateness perturbation remain at higher orders. Then, we apply perturbation theory and find that a third-order approach is enough to show the influence of the satellite's ellipticity in the pericenter dynamics. Finally, we discuss the averaged system in the three-dimensional parametric space, and provide a global description of the flow.

Ultracapacitors for fuel saving in small size hybrid vehicles

NASA Astrophysics Data System (ADS)

Solero, L.; Lidozzi, A.; Serrao, V.; Martellucci, L.; Rossi, E.

The main purpose of the paper is to describe a small size hybrid vehicle having ultracapacitors as on-board storage unit. The vehicle on-board main power supply is achieved by a genset being formed of a 250 cm 3 internal combustion engine and a permanent magnet synchronous electric generator, whereas 4 16V-500F ultracapacitors modules are connected in series in order to supply as well as to store the power peaks during respectively acceleration and braking vehicle modes of operation. The traction power is provided by a permanent magnet synchronous electric motor, whereas a distributed power electronic interface is in charge of all the required electronic conversions as well of controlling the operating conditions for each power unit. The paper discusses the implemented control strategy and shows experimental results on the modes of operation of both generation unit and storage unit.

Long-distance multi-channel bidirectional chaos communication based on synchronized VCSELs subject to chaotic signal injection

NASA Astrophysics Data System (ADS)

Xie, Yi-Yuan; Li, Jia-Chao; He, Chao; Zhang, Zhen-Dong; Song, Ting-Ting; Xu, Chang-Jun; Wang, Gui-Jin

2016-10-01

A novel long-distance multi-channel bidirectional chaos communication system over multiple paths based on two synchronized 1550 nm vertical-cavity surface-emitting lasers (VCSELs) is proposed and studied theoretically. These two responding VCSELs (R-VCSELs) can output similar chaotic signals served as chaotic carrier in two linear polarization (LP) modes with identical signal injection from a driving VCSEL (D-VCSEL), which is subject to optical feedback and optical injection, simultaneously. Through the numerical simulations, high quality chaos synchronization between the two R-VCSELs can be obtained. Besides, the effects of varied qualities of chaos synchronization on communication performances in 20 km single mode fiber (SMF) channels are investigated by regulating different internal parameters mismatch after adopting chaos masking (CMS) technique. With the decrease of the maximum cross correlation coefficient (Max-C) between the two R-VCSELs, the bit error rate (BER) of decoded message increase. Meanwhile, the BER can still be less than 10-9 when the Max-C degrades to 0.982. Based on high quality synchronization, when the dispersion compensating fiber (DCF) links are introduced, 4n messages of 10 Gbit/s can transmit in 180 km SMF channels over n coupling paths, bidirectionally and simultaneously. Thorough tests are carried out with detailed analysis, demonstrating long-distance, multi-channel, bidirectional chaos communication based on VCSELs with chaotic signal injection.

Synchronization of relativistic particles in the hyperbolic Kuramoto model

NASA Astrophysics Data System (ADS)

Ritchie, Louis M.; Lohe, M. A.; Williams, Anthony G.

2018-05-01

We formulate a noncompact version of the Kuramoto model by replacing the invariance group SO(2) of the plane rotations by the noncompact group SO(1, 1). The N equations of the system are expressed in terms of hyperbolic angles αi and are similar to those of the Kuramoto model, except that the trigonometric functions are replaced by hyperbolic functions. Trajectories are generally unbounded, nevertheless synchronization occurs for any positive couplings κi, arbitrary positive multiplicative parameters λi and arbitrary exponents ωi. There are no critical values for the coupling constants. We measure the onset of synchronization by means of several order and disorder parameters. We show numerically and by means of exact solutions for N = 2 that solutions can develop singularities if the coupling constants are negative, or if the initial values are not suitably restricted. We describe a physical interpretation of the system as a cluster of interacting relativistic particles in 1 + 1 dimensions, subject to linear repulsive forces with space-time trajectories parametrized by the rapidity αi. The trajectories synchronize provided that the particle separations remain predominantly time-like, and the synchronized cluster can be viewed as a bound state of N relativistic particle constituents. We extend the defining equations of the system to higher dimensions by means of vector equations which are covariant with respect to SO(p, q).

A Modified Differential Coherent Bit Synchronization Algorithm for BeiDou Weak Signals with Large Frequency Deviation.

PubMed

Han, Zhifeng; Liu, Jianye; Li, Rongbing; Zeng, Qinghua; Wang, Yi

2017-07-04

BeiDou system navigation messages are modulated with a secondary NH (Neumann-Hoffman) code of 1 kbps, where frequent bit transitions limit the coherent integration time to 1 millisecond. Therefore, a bit synchronization algorithm is necessary to obtain bit edges and NH code phases. In order to realize bit synchronization for BeiDou weak signals with large frequency deviation, a bit synchronization algorithm based on differential coherent and maximum likelihood is proposed. Firstly, a differential coherent approach is used to remove the effect of frequency deviation, and the differential delay time is set to be a multiple of bit cycle to remove the influence of NH code. Secondly, the maximum likelihood function detection is used to improve the detection probability of weak signals. Finally, Monte Carlo simulations are conducted to analyze the detection performance of the proposed algorithm compared with a traditional algorithm under the CN0s of 20~40 dB-Hz and different frequency deviations. The results show that the proposed algorithm outperforms the traditional method with a frequency deviation of 50 Hz. This algorithm can remove the effect of BeiDou NH code effectively and weaken the influence of frequency deviation. To confirm the feasibility of the proposed algorithm, real data tests are conducted. The proposed algorithm is suitable for BeiDou weak signal bit synchronization with large frequency deviation.

A dinoflagellate mutant with higher frequency of multiple fission.

PubMed

Lam, C M; Chong, C; Wong, J T

2001-01-01

The dinoflagellate Crypthecodinium cohnii Biecheler propagates by both binary and multiple fission. By a newly developed mutagenesis protocol based on using ethyl methanesulfonate and a cell size screening method, a cell cycle mutant, mf2, was isolated with giant cells which predominantly divide by multiple fission. The average cell size of the mutant mf2 is larger than the control C. cohnii. Cell cycle synchronization experiments suggest that mutant mf2, when compared with the control strain, has a prolonged G1 phase with a corresponding delay of the G2 + M phase.

Short desynchronization episodes prevail in synchronous dynamics of human brain rhythms.

PubMed

Ahn, Sungwoo; Rubchinsky, Leonid L

2013-03-01

Neural synchronization is believed to be critical for many brain functions. It frequently exhibits temporal variability, but it is not known if this variability has a specific temporal patterning. This study explores these synchronization/desynchronization patterns. We employ recently developed techniques to analyze the fine temporal structure of phase-locking to study the temporal patterning of synchrony of the human brain rhythms. We study neural oscillations recorded by electroencephalograms in α and β frequency bands in healthy human subjects at rest and during the execution of a task. While the phase-locking strength depends on many factors, dynamics of synchrony has a very specific temporal pattern: synchronous states are interrupted by frequent, but short desynchronization episodes. The probability for a desynchronization episode to occur decreased with its duration. The transition matrix between synchronized and desynchronized states has eigenvalues close to 0 and 1 where eigenvalue 1 has multiplicity 1, and therefore if the stationary distribution between these states is perturbed, the system converges back to the stationary distribution very fast. The qualitative similarity of this patterning across different subjects, brain states and electrode locations suggests that this may be a general type of dynamics for the brain. Earlier studies indicate that not all oscillatory networks have this kind of patterning of synchronization/desynchronization dynamics. Thus, the observed prevalence of short (but potentially frequent) desynchronization events (length of one cycle of oscillations) may have important functional implications for the brain. Numerous short desynchronizations (as opposed to infrequent, but long desynchronizations) may allow for a quick and efficient formation and break-up of functionally significant neuronal assemblies.

Short desynchronization episodes prevail in synchronous dynamics of human brain rhythms

NASA Astrophysics Data System (ADS)

Ahn, Sungwoo; Rubchinsky, Leonid L.

2013-03-01

Neural synchronization is believed to be critical for many brain functions. It frequently exhibits temporal variability, but it is not known if this variability has a specific temporal patterning. This study explores these synchronization/desynchronization patterns. We employ recently developed techniques to analyze the fine temporal structure of phase-locking to study the temporal patterning of synchrony of the human brain rhythms. We study neural oscillations recorded by electroencephalograms in α and β frequency bands in healthy human subjects at rest and during the execution of a task. While the phase-locking strength depends on many factors, dynamics of synchrony has a very specific temporal pattern: synchronous states are interrupted by frequent, but short desynchronization episodes. The probability for a desynchronization episode to occur decreased with its duration. The transition matrix between synchronized and desynchronized states has eigenvalues close to 0 and 1 where eigenvalue 1 has multiplicity 1, and therefore if the stationary distribution between these states is perturbed, the system converges back to the stationary distribution very fast. The qualitative similarity of this patterning across different subjects, brain states and electrode locations suggests that this may be a general type of dynamics for the brain. Earlier studies indicate that not all oscillatory networks have this kind of patterning of synchronization/desynchronization dynamics. Thus, the observed prevalence of short (but potentially frequent) desynchronization events (length of one cycle of oscillations) may have important functional implications for the brain. Numerous short desynchronizations (as opposed to infrequent, but long desynchronizations) may allow for a quick and efficient formation and break-up of functionally significant neuronal assemblies.

Robot-assisted Extracranial Stereotactic Radiotherapy of Adrenal Metastases in Oligometastatic Non-small Cell Lung Cancer.

PubMed

Celik, Eren; Semrau, Robert; Baues, Christian; Trommer-Nestler, Maike; Baus, Wolfgang; Marnitz, Simone

2017-09-01

The aim of this study was to evaluate the efficacy and toxicity of stereotactic body radiation therapy (SBRT) in the treatment of patients with adrenal metastases in oligometastatic non-small-cell lung cancer (NSCLC). Between November 2012 and May 2015, fifteen patients with oligometastatic non-small cell lung cancer and adrenal metastases were treated with the Cyberknife® system. The primary endpoint was local control. The 1-year and 2-year local control rates were 60% and 46.6%, respectively. The differences in local control for patients with metachronous and synchronous metastases reached statistical significance (p=0.00028). Two-year overall survival of 91.2% for patients with metachronous metastases was also more favourable compared to patients with synchronous adrenal metastases with 42.8%. Extracranial stereotactic radiotherapy with the Cyberknife® is a safe and non-invasive technique that extends the therapeutic spectrum in the treatment of patients with adrenal metastases in oligometastatic NSCLC. Copyright© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Bioinspired Principles for Large-Scale Networked Sensor Systems: An Overview

PubMed Central

Jacobsen, Rune Hylsberg; Zhang, Qi; Toftegaard, Thomas Skjødeberg

2011-01-01

Biology has often been used as a source of inspiration in computer science and engineering. Bioinspired principles have found their way into network node design and research due to the appealing analogies between biological systems and large networks of small sensors. This paper provides an overview of bioinspired principles and methods such as swarm intelligence, natural time synchronization, artificial immune system and intercellular information exchange applicable for sensor network design. Bioinspired principles and methods are discussed in the context of routing, clustering, time synchronization, optimal node deployment, localization and security and privacy. PMID:22163841

Skype interviewing: The new generation of online synchronous interview in qualitative research

PubMed Central

Roudsari, Robab Latifnejad; Taghipour, Ali

2014-01-01

The most commonly used method for data collection in qualitative research is interviewing. With technology changes over the last few decades, the online interview has overcome time and financial constraints, geographical dispersion, and physical mobility boundaries, which have adversely affected onsite interviews. Skype as a synchronous online service offers researchers the possibility of conducting individual interviews as well as small focus groups, comparable to onsite types. This commentary presents the characteristics of the Skype interview as an alternative or supplemental choice to investigators who want to change their conventional approach of interviewing. PMID:24746247

Low power electromagnetic flowmeter providing accurate zero set

NASA Technical Reports Server (NTRS)

Fryer, T. B. (Inventor)

1971-01-01

A low power, small size electromagnetic flowmeter system is described which produces a zero output signal for zero flow. The system comprises an air core type electromagnetic flow transducer, a field current supply circuit for the transducer coils and a pre-amplifier and demodulation circuit connected to the output of the transducer. To prevent spurious signals at zero flow, separate, isolated power supplies are provided for the two circuits. The demodulator includes a pair of synchronous rectifiers which are controlled by signals from the field current supply circuit. Pulse transformer connected in front of the synchronous rectifiers provide isolation between the two circuits.

Skype interviewing: the new generation of online synchronous interview in qualitative research.

PubMed

Janghorban, Roksana; Latifnejad Roudsari, Robab; Taghipour, Ali

2014-01-01

The most commonly used method for data collection in qualitative research is interviewing. With technology changes over the last few decades, the online interview has overcome time and financial constraints, geographical dispersion, and physical mobility boundaries, which have adversely affected onsite interviews. Skype as a synchronous online service offers researchers the possibility of conducting individual interviews as well as small focus groups, comparable to onsite types. This commentary presents the characteristics of the Skype interview as an alternative or supplemental choice to investigators who want to change their conventional approach of interviewing.

Pulse transmission receiver with higher-order time derivative pulse generator

DOEpatents

Dress, Jr., William B.; Smith, Stephen F.

2003-08-12

Systems and methods for pulse-transmission low-power communication modes are disclosed. A pulse transmission receiver includes: a front-end amplification/processing circuit; a synchronization circuit coupled to the front-end amplification/processing circuit; a clock coupled to the synchronization circuit; a trigger signal generator coupled to the clock; and at least one higher-order time derivative pulse generator coupled to the trigger signal generator. The systems and methods significantly reduce lower-frequency emissions from pulse transmission spread-spectrum communication modes, which reduces potentially harmful interference to existing radio frequency services and users and also simultaneously permit transmission of multiple data bits by utilizing specific pulse shapes.

Synchronization in neural nets

NASA Technical Reports Server (NTRS)

Vidal, Jacques J.; Haggerty, John

1988-01-01

The paper presents an artificial neural network concept (the Synchronizable Oscillator Networks) where the instants of individual firings in the form of point processes constitute the only form of information transmitted between joining neurons. In the model, neurons fire spontaneously and regularly in the absence of perturbation. When interaction is present, the scheduled firings are advanced or delayed by the firing of neighboring neurons. Networks of such neurons become global oscillators which exhibit multiple synchronizing attractors. From arbitrary initial states, energy minimization learning procedures can make the network converge to oscillatory modes that satisfy multi-dimensional constraints. Such networks can directly represent routing and scheduling problems that consist of ordering sequences of events.

Synchronous scattering and diffraction from gold nanotextured surfaces with structure factors

NASA Astrophysics Data System (ADS)

Gu, Min-Jhong; Lee, Ming-Tsang; Huang, Chien-Hsun; Wu, Chi-Chun; Chen, Yu-Bin

2018-05-01

Synchronous scattering and diffraction were demonstrated using reflectance from gold nanotextured surfaces at oblique (θi = 15° and 60°) incidence of wavelength λ = 405 nm. Two samples of unique auto-correlation functions were cost-effectively fabricated. Multiple structure factors of their profiles were confirmed with Fourier expansions. Bi-directional reflectance function (BRDF) from these samples provided experimental proofs. On the other hand, standard deviation of height and unique auto-correlation function of each sample were used to generate surfaces numerically. Comparing their BRDF with those of totally random rough surfaces further suggested that structure factors in profile could reduce specular reflection more than totally random roughness.

Multiple Visceral Resections for Synchronous Left and Transverse Colon Adenocarcinoma with Gastrocolic-cutaneous Fistula - Case Report and Literature Review.

PubMed

Bacalbasa, Nicolae; Stoica, Claudia; Balescu, Irina

2017-05-01

Synchronous adenocarcinomas of the colon represent a rare situation, characterized by the presence of at least two colonic malignancies separated by at least 4-cm distance, in the absence of submucosal spread. Gastrocolic-cutaneous fistulas also represent a rare complication associated with the presence of colonic or gastric adenocarcinomas. We present the case of a 61-year-old patient who presented for abdominal pain, vomiting, weight loss and cutaneous exteriorization of purulent liquid. Intraoperatively, a large centro-abdominal tumor with gastroduodenal, pancreatic and colonic invasion was found in association with a synchronous left colonic tumor. The tumors were resected en bloc with distal gastrectomy, cephalic pancreatoduodenectomy, segmental enterectomy, subtotal colectomy and upper abdominal lymph node dissection. The histopathological studies revealed the presence of two synchronous colonic tumors: one located on the transverse colon, with pancreatic, duodeno-jejunal and gastric invasion and gastrocolic-cutaneous fistula, and a second one located on the left colon. Both tumors proved to be moderately differentiated colonic adenocarcinomas. At 1-year follow-up the patient remains free of any recurrent disease. Copyright© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Synchronized vortex shedding and sound radiation from two side-by-side rectangular cylinders of different cross-sectional aspect ratios

DOE Office of Scientific and Technical Information (OSTI.GOV)

Octavianty, Ressa, E-mail: ressa-octavianty@ed.tmu.ac.jp; Asai, Masahito, E-mail: masai@tmu.ac.jp

Synchronized vortex shedding from two side-by-side cylinders and the associated sound radiation were examined experimentally at Reynolds numbers of the order of 10{sup 4} in low-Mach-number flows. In addition to a pair of square cylinders, a pair of rectangular cylinders, one with a square cross section (d × d) and the other with a rectangular cross section (d × c) having a cross-sectional aspect ratio (c/d) of 1.2–1.5, was considered. The center-to-center distance between the two cylinders L/d was 3.6, 4.5, and 6.0; these settings were within the non-biased flow regime for side-by-side square cylinders. In case of a squaremore » cylinder pair, anti-phase synchronized vortex shedding occurring for L/d = 3.6 and 4.5 generated a quadrupole-like sound source which radiated in-phase, planar-symmetric sound in the far field. Synchronized vortex shedding from the two rectangular cylinders with different c/d also occurred with almost the same frequency as the characteristic frequency of the square-cylinder wake in the case of the small center-to-center distance, L/d = 3.6, for all the cylinder pairs examined. The synchronized sound field was anti-phase and asymmetric in amplitude, unlike the case of a square cylinder pair. For larger spacing L/d = 4.5, synchronized vortex shedding and anti-phase sound still occurred, but only for close cross-sectional aspect ratios (c/d = 1.0 and 1.2), and highly modulated sound was radiated with two different frequencies due to non-synchronized vortex shedding from the two cylinders for larger differences in c/d. It was also found that when synchronized vortex shedding occurred, near-wake velocity fluctuations exhibited high spanwise-coherency, with a very sharp spectral peak compared with the single-cylinder case.« less

Synchronization of eukaryotic flagella in vivo: from two to thousands

NASA Astrophysics Data System (ADS)

Goldstein, Raymond E.

2012-02-01

From unicellular organisms as small as a few microns to the largest vertebrates on Earth, we find groups of beating flagella or cilia that exhibit striking spatiotemporal organization. This may take the form of precise frequency and phase locking, as frequently found in the swimming of green algae, or beating with long-wavelength phase modulations known as metachronal waves, seen in ciliates such as Paramecium and in our own respiratory systems. The remarkable similarity in the underlying molecular structure of flagella across the whole eukaryotic world leads naturally to the hypothesis that a similarly universal mechanism might be responsible for synchronization. Although this mechanism is poorly understood, one appealing hypothesis is that it results from hydrodynamic interactions between flagella. This talk will summarize recent work using the unicellular alga Chlamydomonas reinhardtii and its multicellular cousin Volvox carteri to study in detail the nature of flagellar synchronization and its possible hydrodynamic origins.

A Group Neighborhood Average Clock Synchronization Protocol for Wireless Sensor Networks

PubMed Central

Lin, Lin; Ma, Shiwei; Ma, Maode

2014-01-01

Clock synchronization is a very important issue for the applications of wireless sensor networks. The sensors need to keep a strict clock so that users can know exactly what happens in the monitoring area at the same time. This paper proposes a novel internal distributed clock synchronization solution using group neighborhood average. Each sensor node collects the offset and skew rate of the neighbors. Group averaging of offset and skew rate value are calculated instead of conventional point-to-point averaging method. The sensor node then returns compensated value back to the neighbors. The propagation delay is considered and compensated. The analytical analysis of offset and skew compensation is presented. Simulation results validate the effectiveness of the protocol and reveal that the protocol allows sensor networks to quickly establish a consensus clock and maintain a small deviation from the consensus clock. PMID:25120163

Geometric properties-dependent neural synchrony modulated by extracellular subthreshold electric field

NASA Astrophysics Data System (ADS)

Wei, Xile; Si, Kaili; Yi, Guosheng; Wang, Jiang; Lu, Meili

2016-07-01

In this paper, we use a reduced two-compartment neuron model to investigate the interaction between extracellular subthreshold electric field and synchrony in small world networks. It is observed that network synchronization is closely related to the strength of electric field and geometric properties of the two-compartment model. Specifically, increasing the electric field induces a gradual improvement in network synchrony, while increasing the geometric factor results in an abrupt decrease in synchronization of network. In addition, increasing electric field can make the network become synchronous from asynchronous when the geometric parameter is set to a given value. Furthermore, it is demonstrated that network synchrony can also be affected by the firing frequency and dynamical bifurcation feature of single neuron. These results highlight the effect of weak field on network synchrony from the view of biophysical model, which may contribute to further understanding the effect of electric field on network activity.

Synchronous triple occurrence of MALT lymphoma, schwannoma, and adenocarcinoma of the stomach.

PubMed

Choi, Kyeong W; Joo, Mee; Kim, Han S; Lee, Woo Y

2017-06-14

We present a case of a 56-year-old man with 3 synchronous gastric tumors. The patient presented with melena, and 3 gastric abnormalities were detected on gastroduodenoscopic examination, including a small ulcerative lesion in the gastric antrum, a submucosal mass in the gastric body, and severe erosion in the fundus. Histological examination of biopsy samples yielded respective diagnoses of gastric adenocarcinoma, gastritis, and mucosa-associated lymphoid tissue (MALT) lymphoma. The patient first received medication to eradicate any underlying Helicobacter pylori infection, which might have been a cause of the MALT lymphoma. Four weeks later, after examination of repeat biopsy samples revealed that the MALT lymphoma had resolved, the patient underwent subtotal gastrectomy. Further histological examination of resected tissue confirmed the antrum lesion as adenocarcinoma and the body lesion as schwannoma. To our knowledge, this is the first reported case of synchronous triple primary gastric adenocarcinoma, MALT lymphoma, and schwannoma.

A New Equilibrium State for Singly Synchronous Binary Asteroids

NASA Astrophysics Data System (ADS)

Golubov, Oleksiy; Unukovych, Vladyslav; Scheeres, Daniel J.

2018-04-01

The evolution of rotation states of small asteroids is governed by the Yarkovsky–O’Keefe–Radzievskii–Paddack (YORP) effect, nonetheless some asteroids can stop their YORP evolution by attaining a stable equilibrium. The same is true for binary asteroids subjected to the binary YORP (BYORP) effect. Here we discuss a new type of equilibrium that combines these two, which is possible in a singly synchronous binary system. This equilibrium occurs when the normal YORP, the tangential YORP, and the BYORP compensate each other, and tidal torques distribute the angular momentum between the components of the system and dissipate energy. If unperturbed, such a system would remain singly synchronous in perpetuity with constant spin and orbit rates, as the tidal torques dissipate the incoming energy from impinging sunlight at the same rate. The probability of the existence of this kind of equilibrium in a binary system is found to be on the order of a few percent.

Synchronization of Spontaneous Active Motility of Hair Cell Bundles

PubMed Central

Zhang, Tracy-Ying; Ji, Seung; Bozovic, Dolores

2015-01-01

Hair cells of the inner ear exhibit an active process, believed to be crucial for achieving the sensitivity of auditory and vestibular detection. One of the manifestations of the active process is the occurrence of spontaneous hair bundle oscillations in vitro. Hair bundles are coupled by overlying membranes in vivo; hence, explaining the potential role of innate bundle motility in the generation of otoacoustic emissions requires an understanding of the effects of coupling on the active bundle dynamics. We used microbeads to connect small groups of hair cell bundles, using in vitro preparations that maintain their innate oscillations. Our experiments demonstrate robust synchronization of spontaneous oscillations, with either 1:1 or multi-mode phase-locking. The frequency of synchronized oscillation was found to be near the mean of the innate frequencies of individual bundles. Coupling also led to an improved regularity of entrained oscillations, demonstrated by an increase in the quality factor. PMID:26540409

Treatment of multiple synchronous misdiagnosed renal cell cancers in a young patient affected by a "de novo" Von Hippel-Lindau syndrome.

PubMed

Allasia, Marco; Battaglia, Antonino; Pasini, Barbara; Gazzera, Carlo; Calandri, Marco; Bosio, Andrea; Gontero, Paolo; Destefanis, Paolo

2017-02-28

Von Hippel-Lindau (VHL) disease is an autosomal dominant inherited syndrome occurring in one out of 36,000 live births. Diagnosis could be a challenge in patients with no familial VHL history. Renal cancer (RCC) represents one of the most important manifestations. RCC is usually recurrent and multifocal. Actually treating RCC in VHL patients represent a clinical dilemma: the oncological outcomes must be balanced against renal function preservation. A young man with a negative familial history was referred to our department with seven misdiagnosed renal masses. VHL disease was determined through genetic test. The multiple RCCs were treated by surgery and percutaneous thermal ablation by radiofrequency ablation (RFA) with complete control of RCC and no impairment of renal function. This case history confirms that VHL disease has to be suspected in young patients with evidence of synchronous multiple renal masses and in presence of specific clinical criteria.RFA appears to be safe in terms of oncological radicalism and in renal function preservation.In hereditary RCC, we should purpose, whenever it is possible, minimally invasive treatment in terms of low hospital stay and a minimal loss of renal tissue.

On decentralized adaptive full-order sliding mode control of multiple UAVs.

PubMed

Xiang, Xianbo; Liu, Chao; Su, Housheng; Zhang, Qin

2017-11-01

In this study, a novel decentralized adaptive full-order sliding mode control framework is proposed for the robust synchronized formation motion of multiple unmanned aerial vehicles (UAVs) subject to system uncertainty. First, a full-order sliding mode surface in a decentralized manner is designed to incorporate both the individual position tracking error and the synchronized formation error while the UAV group is engaged in building a certain desired geometric pattern in three dimensional space. Second, a decentralized virtual plant controller is constructed which allows the embedded low-pass filter to attain the chattering free property of the sliding mode controller. In addition, robust adaptive technique is integrated in the decentralized chattering free sliding control design in order to handle unknown bounded uncertainties, without requirements for assuming a priori knowledge of bounds on the system uncertainties as stated in conventional chattering free control methods. Subsequently, system robustness as well as stability of the decentralized full-order sliding mode control of multiple UAVs is synthesized. Numerical simulation results illustrate the effectiveness of the proposed control framework to achieve robust 3D formation flight of the multi-UAV system. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.

Temporal Synchronization Analysis for Improving Regression Modeling of Fecal Indicator Bacteria Levels

EPA Science Inventory

Multiple linear regression models are often used to predict levels of fecal indicator bacteria (FIB) in recreational swimming waters based on independent variables (IVs) such as meteorologic, hydrodynamic, and water-quality measures. The IVs used for these analyses are traditiona...

Multiple-parameter bifurcation analysis in a Kuramoto model with time delay and distributed shear

NASA Astrophysics Data System (ADS)

Niu, Ben; Zhang, Jiaming; Wei, Junjie

2018-05-01

In this paper, time delay effect and distributed shear are considered in the Kuramoto model. On the Ott-Antonsen's manifold, through analyzing the associated characteristic equation of the reduced functional differential equation, the stability boundary of the incoherent state is derived in multiple-parameter space. Moreover, very rich dynamical behavior such as stability switches inducing synchronization switches can occur in this equation. With the loss of stability, Hopf bifurcating coherent states arise, and the criticality of Hopf bifurcations is determined by applying the normal form theory and the center manifold theorem. On one hand, theoretical analysis indicates that the width of shear distribution and time delay can both eliminate the synchronization then lead the Kuramoto model to incoherence. On the other, time delay can induce several coexisting coherent states. Finally, some numerical simulations are given to support the obtained results where several bifurcation diagrams are drawn, and the effect of time delay and shear is discussed.

Flexible language constructs for large parallel programs

NASA Technical Reports Server (NTRS)

Rosing, Matthew; Schnabel, Robert

1993-01-01

The goal of the research described is to develop flexible language constructs for writing large data parallel numerical programs for distributed memory (MIMD) multiprocessors. Previously, several models have been developed to support synchronization and communication. Models for global synchronization include SIMD (Single Instruction Multiple Data), SPMD (Single Program Multiple Data), and sequential programs annotated with data distribution statements. The two primary models for communication include implicit communication based on shared memory and explicit communication based on messages. None of these models by themselves seem sufficient to permit the natural and efficient expression of the variety of algorithms that occur in large scientific computations. An overview of a new language that combines many of these programming models in a clean manner is given. This is done in a modular fashion such that different models can be combined to support large programs. Within a module, the selection of a model depends on the algorithm and its efficiency requirements. An overview of the language and discussion of some of the critical implementation details is given.

Synchronous adrenocortical neoplasms, paragangliomas, and pheochromocytomas: syndromic considerations regarding an unusual constellation of endocrine tumors.

PubMed

LeBlanc, Melissa; Tabrizi, Mohsen; Kapsner, Patricia; Hanson, Joshua Anspach

2014-12-01

The most common clinical syndromes presenting with paragangliomas and/or pheochromocytomas as their endocrine components are multiple endocrine neoplasia type 2, neurofibromatosis, Von Hippel-Lindau syndrome, Carney-Stratakis syndrome, Carney triad, and the recently described hereditary paraganglioma syndrome. Only Carney triad is known to also present with adrenocortical adenomas, currently representing the only described syndrome in which all 3 of the aforementioned tumors are found together. In most cases, prototypical lesions of the triad such as gastrointestinal stromal tumor and pulmonary chondromas are also seen. We present a case of a young woman with synchronous paragangliomas, adrenal/extra-adrenal cortical neoplasms, and pheochromocytoma without genetic mutations for multiple endocrine neoplasia 2, Von Hippel-Lindau syndrome, neurofibromatosis, and succinate dehydrogenase. We speculate that this represents a previously undescribed presentation of Carney triad and, at the very least, indicates the need for monitoring for the development of other tumors of the triad. Copyright © 2014 Elsevier Inc. All rights reserved.

A simple, effective media access protocol system for integrated, high data rate networks

NASA Technical Reports Server (NTRS)

Foudriat, E. C.; Maly, K.; Overstreet, C. M.; Khanna, S.; Zhang, L.

1992-01-01

The operation and performance of a dual media access protocol for integrated, gigabit networks are described. Unlike other dual protocols, each protocol supports a different class of traffic. The Carrier Sensed Multiple Access-Ring Network (CSMA/RN) protocol and the Circulating Reservation Packet (CRP) protocol support asynchronous and synchronous traffic, respectively. The two protocols operate with minimal impact upon each other. Performance information demonstrates that they support a complete range of integrated traffic loads, do not require call setup/termination or a special node for synchronous traffic control, and provide effective pre-use and recovery. The CRP also provides guaranteed access and fairness control for the asynchronous system. The paper demonstrates that the CSMA-CRP system fulfills many of the requirements for gigabit LAN-MAN networks most effectively and simply. To accomplish this, CSMA-CRP features are compared against similar ring and bus systems, such as Cambridge Fast Ring, Metaring, Cyclic Reservation Multiple Access, and Distributed Dual Queue Data Bus (DQDB).

Oscillator networks with tissue-specific circadian clocks in plants.

PubMed

Inoue, Keisuke; Araki, Takashi; Endo, Motomu

2017-09-08

Many organisms rely on circadian clocks to synchronize their biological processes with the 24-h rotation of the earth. In mammals, the circadian clock consists of a central clock in the suprachiasmatic nucleus and peripheral clocks in other tissues. The central clock is tightly coupled to synchronize rhythmicity and can organize peripheral clocks through neural and hormonal signals. In contrast to mammals, it has long been assumed that the circadian clocks in each plant cell is able to be entrained by external light, and they are only weakly coupled to each other. Recently, however, several reports have demonstrated that plants have unique oscillator networks with tissue-specific circadian clocks. Here, we introduce our current view regarding tissue-specific properties and oscillator networks of plant circadian clocks. Accumulating evidence suggests that plants have multiple oscillators, which show distinct properties and reside in different tissues. A direct tissue-isolation technique and micrografting have clearly demonstrated that plants have hierarchical oscillator networks consisting of multiple tissue-specific clocks. Copyright © 2017. Published by Elsevier Ltd.

[Preparation of panax notoginseng saponins-tanshinone H(A) composite method for pulmonary delivery with spray-drying method and its characterization].

PubMed

Wang, Hua-Mei; Fu, Ting-Ming; Guo, Li-Wei

2013-02-01

To prepare panax notoginseng saponins-tanshinone II(A) composite particles for pulmonary delivery, in order to explore a dry powder particle preparation method ensuring synchronized arrival of multiple components of traditional Chinese medicine compounds at absorption sites. Panax notoginseng saponins-tanshinone II(A) composite particles were prepared with spray-drying method, and characterized by scanning electron microscopy (SEM), confocal laser scanning microscope (CLSM), X-ray diffraction (XRD), infrared analysis (IR), dry laser particle size analysis, high performance liquid chromatography (HPLC) and the aerodynamic behavior was evaluated by a Next Generation Impactor (NGI). The dry powder particles produced had narrow particle size distribution range and good aerodynamic behavior, and could realize synchronized administration of multiple components. The spray-drying method is used to combine traditional Chinese medicine components with different physical and chemical properties in the same particle, and product into traditional Chinese medicine compound particles in line with the requirements for pulmonary delivery.

Synchronization of tunable asymmetric square-wave pulses in delay-coupled optoelectronic oscillators.

PubMed

Martínez-Llinàs, Jade; Colet, Pere; Erneux, Thomas

2015-03-01

We consider a model for two delay-coupled optoelectronic oscillators under positive delayed feedback as prototypical to study the conditions for synchronization of asymmetric square-wave oscillations, for which the duty cycle is not half of the period. We show that the scenario arising for positive feedback is much richer than with negative feedback. First, it allows for the coexistence of multiple in- and out-of-phase asymmetric periodic square waves for the same parameter values. Second, it is tunable: The period of all the square-wave periodic pulses can be tuned with the ratio of the delays, and the duty cycle of the asymmetric square waves can be changed with the offset phase while the total period remains constant. Finally, in addition to the multiple in- and out-of-phase periodic square waves, low-frequency periodic asymmetric solutions oscillating in phase may coexist for the same values of the parameters. Our analytical results are in agreement with numerical simulations and bifurcation diagrams obtained by using continuation techniques.

Reusable Client-Side JavaScript Modules for Immersive Web-Based Real-Time Collaborative Neuroimage Visualization

PubMed Central

Bernal-Rusiel, Jorge L.; Rannou, Nicolas; Gollub, Randy L.; Pieper, Steve; Murphy, Shawn; Robertson, Richard; Grant, Patricia E.; Pienaar, Rudolph

2017-01-01

In this paper we present a web-based software solution to the problem of implementing real-time collaborative neuroimage visualization. In both clinical and research settings, simple and powerful access to imaging technologies across multiple devices is becoming increasingly useful. Prior technical solutions have used a server-side rendering and push-to-client model wherein only the server has the full image dataset. We propose a rich client solution in which each client has all the data and uses the Google Drive Realtime API for state synchronization. We have developed a small set of reusable client-side object-oriented JavaScript modules that make use of the XTK toolkit, a popular open-source JavaScript library also developed by our team, for the in-browser rendering and visualization of brain image volumes. Efficient realtime communication among the remote instances is achieved by using just a small JSON object, comprising a representation of the XTK image renderers' state, as the Google Drive Realtime collaborative data model. The developed open-source JavaScript modules have already been instantiated in a web-app called MedView, a distributed collaborative neuroimage visualization application that is delivered to the users over the web without requiring the installation of any extra software or browser plugin. This responsive application allows multiple physically distant physicians or researchers to cooperate in real time to reach a diagnosis or scientific conclusion. It also serves as a proof of concept for the capabilities of the presented technological solution. PMID:28507515

Analysis and Application of Microgrids

NASA Astrophysics Data System (ADS)

Yue, Lu

New trends of generating electricity locally and utilizing non-conventional or renewable energy sources have attracted increasing interests due to the gradual depletion of conventional fossil fuel energy sources. The new type of power generation is called Distributed Generation (DG) and the energy sources utilized by Distributed Generation are termed Distributed Energy Sources (DERs). With DGs embedded in the distribution networks, they evolve from passive distribution networks to active distribution networks enabling bidirectional power flows in the networks. Further incorporating flexible and intelligent controllers and employing future technologies, active distribution networks will turn to a Microgrid. A Microgrid is a small-scale, low voltage Combined with Heat and Power (CHP) supply network designed to supply electrical and heat loads for a small community. To further implement Microgrids, a sophisticated Microgrid Management System must be integrated. However, due to the fact that a Microgrid has multiple DERs integrated and is likely to be deregulated, the ability to perform real-time OPF and economic dispatch with fast speed advanced communication network is necessary. In this thesis, first, problems such as, power system modelling, power flow solving and power system optimization, are studied. Then, Distributed Generation and Microgrid are studied and reviewed, including a comprehensive review over current distributed generation technologies and Microgrid Management Systems, etc. Finally, a computer-based AC optimization method which minimizes the total transmission loss and generation cost of a Microgrid is proposed and a wireless communication scheme based on synchronized Code Division Multiple Access (sCDMA) is proposed. The algorithm is tested with a 6-bus power system and a 9-bus power system.

Does Spike-Timing-Dependent Synaptic Plasticity Couple or Decouple Neurons Firing in Synchrony?

PubMed Central

Knoblauch, Andreas; Hauser, Florian; Gewaltig, Marc-Oliver; Körner, Edgar; Palm, Günther

2012-01-01

Spike synchronization is thought to have a constructive role for feature integration, attention, associative learning, and the formation of bidirectionally connected Hebbian cell assemblies. By contrast, theoretical studies on spike-timing-dependent plasticity (STDP) report an inherently decoupling influence of spike synchronization on synaptic connections of coactivated neurons. For example, bidirectional synaptic connections as found in cortical areas could be reproduced only by assuming realistic models of STDP and rate coding. We resolve this conflict by theoretical analysis and simulation of various simple and realistic STDP models that provide a more complete characterization of conditions when STDP leads to either coupling or decoupling of neurons firing in synchrony. In particular, we show that STDP consistently couples synchronized neurons if key model parameters are matched to physiological data: First, synaptic potentiation must be significantly stronger than synaptic depression for small (positive or negative) time lags between presynaptic and postsynaptic spikes. Second, spike synchronization must be sufficiently imprecise, for example, within a time window of 5–10 ms instead of 1 ms. Third, axonal propagation delays should not be much larger than dendritic delays. Under these assumptions synchronized neurons will be strongly coupled leading to a dominance of bidirectional synaptic connections even for simple STDP models and low mean firing rates at the level of spontaneous activity. PMID:22936909

Integrated Multiple Device CMOS-MEMS IMU Systems and RF MEMS Applications

DTIC Science & Technology

2002-12-17

microstructures [7]~[9]. The success of the surface-micromachined electrostatic micromotor in the late 80’s [10] stimulated the industry and government...processed electrostatic synchronous micromotors ,” Sensors Actuators, vol. 20, pp. 48-56, 1989. [11] “ADXL05-monolithic accelerometer with signal

Supplementation with rumen-protected L-arginine-HCl increased fertility in sheep with synchronized estrus.

PubMed

de Chávez, Julio Agustín Ruiz; Guzmán, Adrian; Zamora-Gutiérrez, Diana; Mendoza, Germán David; Melgoza, Luz María; Montes, Sergio; Rosales-Torres, Ana María

2015-08-01

The aim of the present study was to evaluate the effects of L-arginine-HCl supplementation on ovulation rate, fertility, prolificacy, and serum VEGF concentrations in ewes with synchronized oestrus. Thirty Suffolk ewes with a mean body weight of 45 ± 3 kg and a mean body condition score (BCS) of 2.4 ± 0.28 were synchronized for estrus presentation with a progestin-containing sponge (20 mg Chronogest® CR) for 9 days plus PGF2-α (Lutalyse; Pfizer, USA) on day 7 after the insertion of the sponge. The ewes were divided into two groups; i.e., a control group (n = 15) that was fed on the native pasture (basal diet) and an L-arginine-HCl group (n = 15) that received 7.8 g of rumen-protected L-arginine-HCl from day 5 of the sponge insertion until day 25 after mating plus the basal diet. The L-arginine-HCl was administered daily via an esophageal probe between days 5 and 9 of the synchronization protocol and every third day subsequently. Blood samples were drawn from the jugular vein every 6 days throughout the entire experimental period. The results revealed that the L-arginine-HCl supplementation increased fertility during the synchronized estrus (P = 0.05). However, no effects were observed on the final BCS (P = 0.78), estrus presentation (P = 0.33), multiple ovulations (P = 0.24), prolificacy (P = 0.63), or serum VEGF concentration. In conclusion, L-arginine-HCl supplementation during the period used in this study increased fertility in sheep with synchronized estrus possibly due to improved embryo-fetal survival during early pregnancy.

Finding the beat: a neural perspective across humans and non-human primates.

PubMed

Merchant, Hugo; Grahn, Jessica; Trainor, Laurel; Rohrmeier, Martin; Fitch, W Tecumseh

2015-03-19

Humans possess an ability to perceive and synchronize movements to the beat in music ('beat perception and synchronization'), and recent neuroscientific data have offered new insights into this beat-finding capacity at multiple neural levels. Here, we review and compare behavioural and neural data on temporal and sequential processing during beat perception and entrainment tasks in macaques (including direct neural recording and local field potential (LFP)) and humans (including fMRI, EEG and MEG). These abilities rest upon a distributed set of circuits that include the motor cortico-basal-ganglia-thalamo-cortical (mCBGT) circuit, where the supplementary motor cortex (SMA) and the putamen are critical cortical and subcortical nodes, respectively. In addition, a cortical loop between motor and auditory areas, connected through delta and beta oscillatory activity, is deeply involved in these behaviours, with motor regions providing the predictive timing needed for the perception of, and entrainment to, musical rhythms. The neural discharge rate and the LFP oscillatory activity in the gamma- and beta-bands in the putamen and SMA of monkeys are tuned to the duration of intervals produced during a beat synchronization-continuation task (SCT). Hence, the tempo during beat synchronization is represented by different interval-tuned cells that are activated depending on the produced interval. In addition, cells in these areas are tuned to the serial-order elements of the SCT. Thus, the underpinnings of beat synchronization are intrinsically linked to the dynamics of cell populations tuned for duration and serial order throughout the mCBGT. We suggest that a cross-species comparison of behaviours and the neural circuits supporting them sets the stage for a new generation of neurally grounded computational models for beat perception and synchronization. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

Popular song and lyrics synchronization and its application to music information retrieval

NASA Astrophysics Data System (ADS)

Chen, Kai; Gao, Sheng; Zhu, Yongwei; Sun, Qibin

2006-01-01

An automatic synchronization system of the popular song and its lyrics is presented in the paper. The system includes two main components: a) automatically detecting vocal/non-vocal in the audio signal and b) automatically aligning the acoustic signal of the song with its lyric using speech recognition techniques and positioning the boundaries of the lyrics in its acoustic realization at the multiple levels simultaneously (e.g. the word / syllable level and phrase level). The GMM models and a set of HMM-based acoustic model units are carefully designed and trained for the detection and alignment. To eliminate the severe mismatch due to the diversity of musical signal and sparse training data available, the unsupervised adaptation technique such as maximum likelihood linear regression (MLLR) is exploited for tailoring the models to the real environment, which improves robustness of the synchronization system. To further reduce the effect of the missed non-vocal music on alignment, a novel grammar net is build to direct the alignment. As we know, this is the first automatic synchronization system only based on the low-level acoustic feature such as MFCC. We evaluate the system on a Chinese song dataset collecting from 3 popular singers. We obtain 76.1% for the boundary accuracy at the syllable level (BAS) and 81.5% for the boundary accuracy at the phrase level (BAP) using fully automatic vocal/non-vocal detection and alignment. The synchronization system has many applications such as multi-modality (audio and textual) content-based popular song browsing and retrieval. Through the study, we would like to open up the discussion of some challenging problems when developing a robust synchronization system for largescale database.

Synchronization transition in neuronal networks composed of chaotic or non-chaotic oscillators.

PubMed

Xu, Kesheng; Maidana, Jean Paul; Castro, Samy; Orio, Patricio

2018-05-30

Chaotic dynamics has been shown in the dynamics of neurons and neural networks, in experimental data and numerical simulations. Theoretical studies have proposed an underlying role of chaos in neural systems. Nevertheless, whether chaotic neural oscillators make a significant contribution to network behaviour and whether the dynamical richness of neural networks is sensitive to the dynamics of isolated neurons, still remain open questions. We investigated synchronization transitions in heterogeneous neural networks of neurons connected by electrical coupling in a small world topology. The nodes in our model are oscillatory neurons that - when isolated - can exhibit either chaotic or non-chaotic behaviour, depending on conductance parameters. We found that the heterogeneity of firing rates and firing patterns make a greater contribution than chaos to the steepness of the synchronization transition curve. We also show that chaotic dynamics of the isolated neurons do not always make a visible difference in the transition to full synchrony. Moreover, macroscopic chaos is observed regardless of the dynamics nature of the neurons. However, performing a Functional Connectivity Dynamics analysis, we show that chaotic nodes can promote what is known as multi-stable behaviour, where the network dynamically switches between a number of different semi-synchronized, metastable states.

Performance of hybrid system for fluorescence and micro-computed tomography in synchronous mode

NASA Astrophysics Data System (ADS)

Liu, Xin; Zhang, Yi; Liu, Fei; Guo, Xiaolian; Wang, Xin; Bai, Jing

2010-11-01

Fluorescence diffuse optical tomography (FDOT) plays an important role in studying physiological and pathological processes of small animals in vivo. The low spatial resolution, however, limits the ability of FDOT in resolving the biodistributions of fluorescent markers. The anatomical information provided by X-ray computed tomography (CT) can be used to improve the image quality of FDOT. However, in most hybrid FDOT/CT systems, the projection data sets of optics and X-ray are acquired sequentially, which increases the acquisition time and bring in the unwanted soft tissue displacement. In this paper, we evaluate the performance of a synchronous FDOT/CT system, which allows for faster and concurrent imaging. Compared with previous FDOT/CT systems, the two subsystems (FDOT and CT) acquire projection images in synchronous mode, so the body position can keep consistent in the same projection data acquired by both subsystems. The experimental results of phantom and in vivo experiments suggest that the reconstruction quality of FDOT can be significantly improved when structural a priori information is utilized to constrain the reconstruction process. On the other hand, the synchronous FDOT/CT system decreases the imaging time.

Coupling of protein localization and cell movements by a dynamically localized response regulator in Myxococcus xanthus

PubMed Central

Leonardy, Simone; Freymark, Gerald; Hebener, Sabrina; Ellehauge, Eva; Søgaard-Andersen, Lotte

2007-01-01

Myxococcus xanthus cells harbor two motility machineries, type IV pili (Tfp) and the A-engine. During reversals, the two machineries switch polarity synchronously. We present a mechanism that synchronizes this polarity switching. We identify the required for motility response regulator (RomR) as essential for A-motility. RomR localizes in a bipolar, asymmetric pattern with a large cluster at the lagging cell pole. The large RomR cluster relocates to the new lagging pole in parallel with cell reversals. Dynamic RomR localization is essential for cell reversals, suggesting that RomR relocalization induces the polarity switching of the A-engine. The analysis of RomR mutants shows that the output domain targets RomR to the poles and the receiver domain is essential for dynamic localization. The small GTPase MglA establishes correct RomR polarity, and the Frz two-component system regulates dynamic RomR localization. FrzS localizes with Tfp at the leading pole and relocates in an Frz-dependent manner to the opposite pole during reversals; FrzS and RomR localize and oscillate independently. The Frz system synchronizes these oscillations and thus the synchronous polarity switching of the motility machineries. PMID:17932488

The effect of time synchronization of wireless sensors on the modal analysis of structures

NASA Astrophysics Data System (ADS)

Krishnamurthy, V.; Fowler, K.; Sazonov, E.

2008-10-01

Driven by the need to reduce the installation cost and maintenance cost of structural health monitoring (SHM) systems, wireless sensor networks (WSNs) are becoming increasingly popular. Perfect time synchronization amongst the wireless sensors is a key factor enabling the use of low-cost, low-power WSNs for structural health monitoring applications based on output-only modal analysis of structures. In this paper we present a theoretical framework for analysis of the impact created by time delays in the measured system response on the reconstruction of mode shapes using the popular frequency domain decomposition (FDD) technique. This methodology directly estimates the change in mode shape values based on sensor synchronicity. We confirm the proposed theoretical model by experimental validation in modal identification experiments performed on an aluminum beam. The experimental validation was performed using a wireless intelligent sensor and actuator network (WISAN) which allows for close time synchronization between sensors (0.6-10 µs in the tested configuration) and guarantees lossless data delivery under normal conditions. The experimental results closely match theoretical predictions and show that even very small delays in output response impact the mode shapes.

Effect of gap junctions on the firing patterns and synchrony for different external inputs in the striatal fast-spiking neuron network.

PubMed

Zhang, Mingming; Zhao, Zongya; He, Ping; Wang, Jue

2014-01-01

Gap junctions are the mechanism for striatal fast-spiking interneurons (FSIs) to interconnect with each other and play an important role in determining the physiological functioning of the FSIs. To investigate the effect of gap junctions on the firing activities and synchronization of the network for different external inputs, a simple network with least connections and a Newman-Watts small-world network were constructed. Our research shows that both properties of neural networks are related to the conductance of the gap junctions, as well as the frequency and correlation of the external inputs. The effect of gap junctions on the synchronization of network is different for inputs with different frequencies and correlations. The addition of gap junctions can promote the network synchrony in some conditions but suppress it in others, and they can inhibit the firing activities in most cases. Both the firing rate and synchronization of the network increase along with the increase of the electrical coupling strength for inputs with low frequency and high correlation. Thus, the network of coupled FSIs can act as a detector for synchronous synaptic input from cortex and thalamus.

Study of dispersed small wind systems interconnected with a utility distribution system

NASA Astrophysics Data System (ADS)

Curtice, D.; Patton, J.; Bohn, J.; Sechan, N.

1980-03-01

Operating problems for various penetrations of small wind systems connected to the distribution system on a utility are defined. Protection equipment, safety hazards, feeder voltage regulation, line losses, and voltage flicker problems are studied, assuming different small wind systems connected to an existing distribution system. To identify hardware deficiencies, possible solutions provided by off-the-shelf hardware and equipment are assessed. Results of the study indicate that existing techniques are inadequate for detecting isolated operation of a small wind system. Potential safety hazards posed by small wind systems are adequately handled by present work procedures although these procedures require a disconnect device at synchronous generator and self commutated inverter small wind systems.

Complex transitions between spike, burst or chaos synchronization states in coupled neurons with coexisting bursting patterns

NASA Astrophysics Data System (ADS)

Gu, Hua-Guang; Chen, Sheng-Gen; Li, Yu-Ye

2015-05-01

We investigated the synchronization dynamics of a coupled neuronal system composed of two identical Chay model neurons. The Chay model showed coexisting period-1 and period-2 bursting patterns as a parameter and initial values are varied. We simulated multiple periodic and chaotic bursting patterns with non-(NS), burst phase (BS), spike phase (SS), complete (CS), and lag synchronization states. When the coexisting behavior is near period-2 bursting, the transitions of synchronization states of the coupled system follows very complex transitions that begins with transitions between BS and SS, moves to transitions between CS and SS, and to CS. Most initial values lead to the CS state of period-2 bursting while only a few lead to the CS state of period-1 bursting. When the coexisting behavior is near period-1 bursting, the transitions begin with NS, move to transitions between SS and BS, to transitions between SS and CS, and then to CS. Most initial values lead to the CS state of period-1 bursting but a few lead to the CS state of period-2 bursting. The BS was identified as chaos synchronization. The patterns for NS and transitions between BS and SS are insensitive to initial values. The patterns for transitions between CS and SS and the CS state are sensitive to them. The number of spikes per burst of non-CS bursting increases with increasing coupling strength. These results not only reveal the initial value- and parameter-dependent synchronization transitions of coupled systems with coexisting behaviors, but also facilitate interpretation of various bursting patterns and synchronization transitions generated in the nervous system with weak coupling strength. Project supported by the National Natural Science Foundation of China (Grant Nos. 11372224 and 11402039) and the Fundamental Research Funds for Central Universities designated to Tongji University (Grant No. 1330219127).

Emergence of multiple synchronization modes in hydrodynamically-coupled cilia

NASA Astrophysics Data System (ADS)

Guo, Hanliang; Kanso, Eva

2016-11-01

Motile cilia and flagella exhibit different phase coordinations. For example, closely swimming spermatozoa are observed to synchronize together; bi-flagellates Chlamydomonas regulate the flagella in a "breast-stroke" fashion; cilia on the surface of Paramecium beat in a fixed phase lag in an orchestrated wave like fashion. Experimental evidence suggests that phase coordinations can be achieved solely via hydrodynamical interactions. However, the exact mechanisms behind it remain illusive. Here, adapting a "geometric switch" model, we observe different synchronization modes in pairs of hydrodynamically-coupled cilia by changing physical parameters such as the strength of the cilia internal motor and the separation distance between cilia. Interestingly, we find regions in the parameter space where the coupled cilia reach stable phase coordinations and regions where the phase coordinations are sensitive to perturbations. We also find that leaning into the fluid reduces the sensitivity to perturbations, and produces stable phase coordination that is neither in-phase nor anti-phase, which could explain the origin of metachronal waves in large cilia populations.

Pulse-coupled neural nets: translation, rotation, scale, distortion, and intensity signal invariance for images.

PubMed

Johnson, J L

1994-09-10

The linking-field neural network model of Eckhorn et al. [Neural Comput. 2, 293-307 (1990)] was introduced to explain the experimentally observed synchronous activity among neural assemblies in the cat cortex induced by feature-dependent visual activity. The model produces synchronous bursts of pulses from neurons with similar activity, effectively grouping them by phase and pulse frequency. It gives a basic new function: grouping by similarity. The synchronous bursts are obtained in the limit of strong linking strengths. The linking-field model in the limit of moderate-to-weak linking characterized by few if any multiple bursts is investigated. In this limit dynamic, locally periodic traveling waves exist whose time signal encodes the geometrical structure of a two-dimensional input image. The signal can be made insensitive to translation, scale, rotation, distortion, and intensity. The waves transmit information beyond the physical interconnect distance. The model is implemented in an optical hybrid demonstration system. Results of the simulations and the optical system are presented.

Synchronization of multiple 3-DOF helicopters under actuator faults and saturations with prescribed performance.

PubMed

Yang, Huiliao; Jiang, Bin; Yang, Hao; Liu, Hugh H T

2018-04-01

The distributed cooperative control strategy is proposed to make the networked nonlinear 3-DOF helicopters achieve the attitude synchronization in the presence of actuator faults and saturations. Based on robust adaptive control, the proposed control method can both compensate the uncertain partial loss of control effectiveness and deal with the system uncertainties. To address actuator saturation problem, the control scheme is designed to ensure that the saturation constraint on the actuation will not be violated during the operation in spite of the actuator faults. It is shown that with the proposed control strategy, both the tracking errors of the leading helicopter and the attitude synchronization errors of each following helicopter are bounded in the existence of faulty actuators and actuator saturations. Moreover, the state responses of the entire group would not exceed the predesigned performance functions which are totally independent from the underlaying interaction topology. Simulation results illustrate the effectiveness of the proposed control scheme. Copyright © 2018 ISA. Published by Elsevier Ltd. All rights reserved.

Development of a time synchronization methodology for a wireless seismic array

NASA Astrophysics Data System (ADS)

Moure-García, David; Torres-González, Pedro; del Río, Joaquín; Mihai, Daniel; Domínguez Cerdeña, Itahiza

2017-04-01

Seismic arrays have multiple applications. In the past, the main use was nuclear tests monitoring that began in mid-twentieth century. The major difference with a seismic network is the hypocenter location procedure. With a seismic network the hypocenter's 3D coordinates are calculated while using an array, the source direction of the seismic signal is determined. Seismic arrays are used in volcanology to obtain the source azimuth of volcanic signals related to fluids movement, magma and/or gases, that do not show a clear seismic phases' onset. A key condition in the seismic array operativity is the temporal synchronization of all the sensors, better than 1 microsecond. Because of that, usually all sensors are connected to the acquisition system by cable to ensure an identical sampling time. In this work we present the design of a wireless low-cost and low-power consumption volcanic monitoring seismic array where all nodes (sensors) acquire data synchronously and transmit them to the center node where a coherent signal is pursued in near real time.

Decoding synchronized oscillations within the brain: phase-delayed inhibition provides a robust mechanism for creating a sharp synchrony filter.

PubMed

Patel, Mainak; Joshi, Badal

2013-10-07

The widespread presence of synchronized neuronal oscillations within the brain suggests that a mechanism must exist that is capable of decoding such activity. Two realistic designs for such a decoder include: (1) a read-out neuron with a high spike threshold, or (2) a phase-delayed inhibition network motif. Despite requiring a more elaborate network architecture, phase-delayed inhibition has been observed in multiple systems, suggesting that it may provide inherent advantages over simply imposing a high spike threshold. In this work, we use a computational and mathematical approach to investigate the efficacy of the phase-delayed inhibition motif in detecting synchronized oscillations. We show that phase-delayed inhibition is capable of creating a synchrony detector with sharp synchrony filtering properties that depend critically on the time course of inputs. Additionally, we show that phase-delayed inhibition creates a synchrony filter that is far more robust than that created by a high spike threshold. Copyright © 2013 Elsevier Ltd. All rights reserved.

Coordinated Beating of Algal Flagella is Mediated by Basal Coupling

NASA Astrophysics Data System (ADS)

Wan, Kirsty; Goldstein, Raymond

Cilia or flagella often exhibit synchronized behavior. This includes phase-locking, as seen in Chlamydomonas, and metachronal wave formation in the respiratory cilia of higher organisms. Since the observations by Gray and Rothschild of phase synchrony of nearby swimming spermatozoa, it has been a working hypothesis that synchrony arises from hydrodynamic interactions between beating filaments. Recent work on the dynamics of physically separated pairs of flagella isolated from the multicellular alga Volvox has shown that hydrodynamic coupling alone is sufficient for synchrony. However, the situation is more complex when considering multiple flagella on a single cell. We suggest that a mechanism, internal to the cell, provides an additional flagellar coupling. For instance, flagella of Chlamydomonas mutants deficient in filamentary connections between basal bodies are found to display markedly different synchronization from the wildtype. Diverse flagellar coordination strategies found in quadri-, octo- and hexadecaflagellates reveal further evidence that intracellular couplings between flagellar basal bodies compete with hydrodynamic interactions to determine the precise form of flagellar synchronization in unicellular algae.

An Optimal Mobile Service for Telecare Data Synchronization using a Role-based Access Control Model and Mobile Peer-to-Peer Technology.

PubMed

Ke, Chih-Kun; Lin, Zheng-Hua

2015-09-01

The progress of information and communication technologies (ICT) has promoted the development of healthcare which has enabled the exchange of resources and services between organizations. Organizations want to integrate mobile devices into their hospital information systems (HIS) due to the convenience to employees who are then able to perform specific healthcare processes from any location. The collection and merage of healthcare data from discrete mobile devices are worth exploring possible ways for further use, especially in remote districts without public data network (PDN) to connect the HIS. In this study, we propose an optimal mobile service which automatically synchronizes the telecare file resources among discrete mobile devices. The proposed service enforces some technical methods. The role-based access control model defines the telecare file resources accessing mechanism; the symmetric data encryption method protects telecare file resources transmitted over a mobile peer-to-peer network. The multi-criteria decision analysis method, ELECTRE (Elimination Et Choice Translating Reality), evaluates multiple criteria of the candidates' mobile devices to determine a ranking order. This optimizes the synchronization of telecare file resources among discrete mobile devices. A prototype system is implemented to examine the proposed mobile service. The results of the experiment show that the proposed mobile service can automatically and effectively synchronize telecare file resources among discrete mobile devices. The contribution of this experiment is to provide an optimal mobile service that enhances the security of telecare file resource synchronization and strengthens an organization's mobility.

Chaotic phase synchronization in bursting-neuron models driven by a weak periodic force

NASA Astrophysics Data System (ADS)

Ando, Hiroyasu; Suetani, Hiromichi; Kurths, Jürgen; Aihara, Kazuyuki

2012-07-01

We investigate the entrainment of a neuron model exhibiting a chaotic spiking-bursting behavior in response to a weak periodic force. This model exhibits two types of oscillations with different characteristic time scales, namely, long and short time scales. Several types of phase synchronization are observed, such as 1:1 phase locking between a single spike and one period of the force and 1:l phase locking between the period of slow oscillation underlying bursts and l periods of the force. Moreover, spiking-bursting oscillations with chaotic firing patterns can be synchronized with the periodic force. Such a type of phase synchronization is detected from the position of a set of points on a unit circle, which is determined by the phase of the periodic force at each spiking time. We show that this detection method is effective for a system with multiple time scales. Owing to the existence of both the short and the long time scales, two characteristic phenomena are found around the transition point to chaotic phase synchronization. One phenomenon shows that the average time interval between successive phase slips exhibits a power-law scaling against the driving force strength and that the scaling exponent has an unsmooth dependence on the changes in the driving force strength. The other phenomenon shows that Kuramoto's order parameter before the transition exhibits stepwise behavior as a function of the driving force strength, contrary to the smooth transition in a model with a single time scale.

Administration of Luteinizing Hormone Releasing Hormone Agonist for Synchronization of Estrus and Generation of Pseudopregnancy for Embryo Transfer in Rats

PubMed Central

Borjeson, Tiffany M; Pang, Jassia; Fox, James G; García, Alexis

2014-01-01

In the past decade, the use of genetically engineered rats has increased exponentially; therefore, the ability to perform embryo transfer (ET) in rats to rederive, reanimate, or create mutant rat lines is increasingly important. However, the successful generation of pseudopregnant female rats for ET represents a limiting factor. We here evaluated the subcutaneous administration of 40 µg luteinizing hormone releasing hormone agonist (LHRHa) for estrus synchronization during the development and implementation of a rat ET program. Our first experiment assessed endogenous estrus cycling patterns by examining vaginal cytology without administration of LHRHa in 5-wk-old peripubertal Sprague–Dawley female rats. These rats then received LHRHa at approximately 7 wk of age; 57% of the rats were synchronized in proestrus or estrus as assessed by vaginal cytology 96 h later. In a second experiment, 8-wk-old virgin, unmanipulated Sprague–Dawley female rats received LHRHa; 55% were synchronized in proestrus or estrus 96 h later. Copulatory plugs were confirmed in 28% and 82% of the rats that had been synchronized in the first and second experiments, respectively, and mated with vasectomized male rats. Embryo transfer surgery was performed, and live pups were born from both fresh and cryopreserved transgenic rat embryos. Our results indicate that subcutaneous administration of 40 µg LHRHa followed by examination of vaginal cytology 96 h later is an effective technique to generate multiple pseudopregnant recipient rats for use in an ET program. PMID:24827564

Quantum internet using code division multiple access

PubMed Central

Zhang, Jing; Liu, Yu-xi; Özdemir, Şahin Kaya; Wu, Re-Bing; Gao, Feifei; Wang, Xiang-Bin; Yang, Lan; Nori, Franco

2013-01-01

A crucial open problem inS large-scale quantum networks is how to efficiently transmit quantum data among many pairs of users via a common data-transmission medium. We propose a solution by developing a quantum code division multiple access (q-CDMA) approach in which quantum information is chaotically encoded to spread its spectral content, and then decoded via chaos synchronization to separate different sender-receiver pairs. In comparison to other existing approaches, such as frequency division multiple access (FDMA), the proposed q-CDMA can greatly increase the information rates per channel used, especially for very noisy quantum channels. PMID:23860488

Asynchronous updates can promote the evolution of cooperation on multiplex networks

NASA Astrophysics Data System (ADS)

Allen, James M.; Hoyle, Rebecca B.

2017-04-01

We study the importance to the frequency of cooperation of the choice of updating strategies in a game played asynchronously or synchronously across layers in a multiplex network. Updating asynchronously in the public goods game leads to higher frequencies of cooperation compared to synchronous updates. How large this effect is depends on the sensitivity of the game dynamics to changes in the number of cooperators surrounding a player, with the largest effect observed when players payoffs are small. The discovery of this effect enhances understanding of cooperation on multiplex networks, and demonstrates a new way to maintain cooperation in these systems.

[One-stage Operation through the Same Skin Incision for Synchronous Double Primary Breast and Lung Cancer;Report of a Case].

PubMed

Takahashi, Noriyuki; Kuga, Yoko; Uno, Satoko; Saito, Keita

2018-02-01

A 75-year-old woman noticed a small mass in the right side breast and consulted our hospital. The results of the detailed examination indicated the synchronous double primary right breast cancer and the same side lung cancer (rS5). One-stage operation from the same skin incision was scheduled. Volume rendering (VR) of computed tomography (CT)-scan was very useful in deciding the position and the length of the skin incision. The breast tumor resection and the right middle lobe resection were successfully performed through 6.5 cm skin incision.

Spinal cord stimulation alleviates motor deficits in a primate model of Parkinson disease.

PubMed

Santana, Maxwell B; Halje, Pär; Simplício, Hougelle; Richter, Ulrike; Freire, Marco Aurelio M; Petersson, Per; Fuentes, Romulo; Nicolelis, Miguel A L

2014-11-19

Although deep brain electrical stimulation can alleviate the motor symptoms of Parkinson disease (PD), just a small fraction of patients with PD can take advantage of this procedure due to its invasive nature. A significantly less invasive method--epidural spinal cord stimulation (SCS)--has been suggested as an alternative approach for symptomatic treatment of PD. However, the mechanisms underlying motor improvements through SCS are unknown. Here, we show that SCS reproducibly alleviates motor deficits in a primate model of PD. Simultaneous neuronal recordings from multiple structures of the cortico-basal ganglia-thalamic loop in parkinsonian monkeys revealed abnormal highly synchronized neuronal activity within each of these structures and excessive functional coupling among them. SCS disrupted this pathological circuit behavior in a manner that mimics the effects caused by pharmacological dopamine replacement therapy or deep brain stimulation. These results suggest that SCS should be considered as an additional treatment option for patients with PD. Copyright © 2014 Elsevier Inc. All rights reserved.

Mental Fatigue and Spatial References Impair Soccer Players' Physical and Tactical Performances

PubMed Central

Coutinho, Diogo; Gonçalves, Bruno; Travassos, Bruno; Wong, Del P.; Coutts, Aaron J.; Sampaio, Jaime E

2017-01-01

This study examined the effects of mental fatigue and additional corridor and pitch sector lines on players' physical and tactical performances during soccer small-sided games. Twelve youth players performed four Gk+6vs6+Gk small-sided games. Prior to the game, one team performed a motor coordination task to induce mental fatigue, while the other one performed a control task. A repeated measures design allowed to compare players' performances across four conditions: (a) with mental fatigue against opponents without mental fatigue in a normal pitch (MEN), (b) with mental fatigue on a pitch with additional reference lines (#MEN); (c) without mental fatigue against mentally fatigued opponents on a normal pitch (CTR); and (d) without mental fatigue on a pitch with reference lines (#CTR). Player's physical performance was assessed by the distance covered per minute and the number of accelerations and decelerations (0.5–3.0 m/s2; > −3.0 m/s2). Positional data was used to determine individual (spatial exploration index, time synchronized in longitudinal and lateral directions) and team-related variables (length, width, speed of dispersion and contraction). Unclear effects were found for the physical activity measures in most of the conditions. There was a small decrease in time spent laterally synchronized and a moderate decrease in the contraction speed when MEN compared to the CTR. Also, there was a small decrease in the time spent longitudinally synchronized during the #MEN condition compared to MEN. The results showed that mental fatigue affects the ability to use environmental information and players' positioning, while the additional reference lines may have enhanced the use of less relevant information to guide their actions during the #MEN condition. Overall, coaches could manipulate the mental fatigue and reference lines to induce variability and adaptation in young soccer players' behavior. PMID:28983273

An Impulse Electric Motor for Driving Recording Instruments

NASA Technical Reports Server (NTRS)

Joachim, W F

1923-01-01

The chief purpose in undertaking the development of this synchronous motor was the creation of a very small, compact power source, capable of driving the film drums of the recording aircraft instruments designed by the staff of the National Advisory Committee for Aeronautics.

Synchronous high speed multi-point velocity profile measurement by heterodyne interferometry

NASA Astrophysics Data System (ADS)

Hou, Xueqin; Xiao, Wen; Chen, Zonghui; Qin, Xiaodong; Pan, Feng

2017-02-01

This paper presents a synchronous multipoint velocity profile measurement system, which acquires the vibration velocities as well as images of vibrating objects by combining optical heterodyne interferometry and a high-speed CMOS-DVR camera. The high-speed CMOS-DVR camera records a sequence of images of the vibrating object. Then, by extracting and processing multiple pixels at the same time, a digital demodulation technique is implemented to simultaneously acquire the vibrating velocity of the target from the recorded sequences of images. This method is validated with an experiment. A piezoelectric ceramic plate with standard vibration characteristics is used as the vibrating target, which is driven by a standard sinusoidal signal.

A Novel Switching-Based Control Framework for Improved Task Performance in Teleoperation System With Asymmetric Time-Varying Delays.

PubMed

Zhai, Di-Hua; Xia, Yuanqing

2018-02-01

This paper addresses the adaptive control for task-space teleoperation systems with constrained predefined synchronization error, where a novel switched control framework is investigated. Based on multiple Lyapunov-Krasovskii functionals method, the stability of the resulting closed-loop system is established in the sense of state-independent input-to-output stability. Compared with previous work, the developed method can simultaneously handle the unknown kinematics/dynamics, asymmetric varying time delays, and prescribed performance control in a unified framework. It is shown that the developed controller can guarantee the prescribed transient-state and steady-state synchronization performances between the master and slave robots, which is demonstrated by the simulation study.

Multiple effect of social influence on cooperation in interdependent network games.

PubMed

Jiang, Luo-Luo; Li, Wen-Jing; Wang, Zhen

2015-10-01

The social influence exists widely in the human society, where individual decision-making process (from congressional election to electronic commerce) may be affected by the attitude and behavior of others belonging to different social networks. Here, we couple the snowdrift (SD) game and the prisoner's dilemma (PD) game on two interdependent networks, where strategies in both games are associated by social influence to mimick the majority rule. More accurately, individuals' strategies updating refers to social learning (based on payoff difference) and above-mentioned social influence (related with environment of interdependent group), which is controlled by social influence strength s. Setting s = 0 decouples the networks and returns the traditional network game; while its increase involves the interactions between networks. By means of numerous Monte Carlo simulations, we find that such a mechanism brings multiple influence to the evolution of cooperation. Small s leads to unequal cooperation level in both games, because social learning is still the main updating rule for most players. Though intermediate and large s guarantees the synchronized evolution of strategy pairs, cooperation finally dies out and reaches a completely dominance in both cases. Interestingly, these observations are attributed to the expansion of cooperation clusters. Our work may provide a new understanding to the emergence of cooperation in intercorrelated social systems.

Multiple effect of social influence on cooperation in interdependent network games

NASA Astrophysics Data System (ADS)

Jiang, Luo-Luo; Li, Wen-Jing; Wang, Zhen

2015-10-01

The social influence exists widely in the human society, where individual decision-making process (from congressional election to electronic commerce) may be affected by the attitude and behavior of others belonging to different social networks. Here, we couple the snowdrift (SD) game and the prisoner’s dilemma (PD) game on two interdependent networks, where strategies in both games are associated by social influence to mimick the majority rule. More accurately, individuals’ strategies updating refers to social learning (based on payoff difference) and above-mentioned social influence (related with environment of interdependent group), which is controlled by social influence strength s. Setting s = 0 decouples the networks and returns the traditional network game; while its increase involves the interactions between networks. By means of numerous Monte Carlo simulations, we find that such a mechanism brings multiple influence to the evolution of cooperation. Small s leads to unequal cooperation level in both games, because social learning is still the main updating rule for most players. Though intermediate and large s guarantees the synchronized evolution of strategy pairs, cooperation finally dies out and reaches a completely dominance in both cases. Interestingly, these observations are attributed to the expansion of cooperation clusters. Our work may provide a new understanding to the emergence of cooperation in intercorrelated social systems.

Market-Based Coordination and Auditing Mechanisms for Self-Interested Multi-Robot Systems

ERIC Educational Resources Information Center

Ham, MyungJoo

2009-01-01

We propose market-based coordinated task allocation mechanisms, which allocate complex tasks that require synchronized and collaborated services of multiple robot agents to robot agents, and an auditing mechanism, which ensures proper behaviors of robot agents by verifying inter-agent activities, for self-interested, fully-distributed, and…

Multiple channel programmable coincidence counter

DOEpatents

Arnone, Gaetano J.

1990-01-01

A programmable digital coincidence counter having multiple channels and featuring minimal dead time. Neutron detectors supply electrical pulses to a synchronizing circuit which in turn inputs derandomized pulses to an adding circuit. A random access memory circuit connected as a programmable length shift register receives and shifts the sum of the pulses, and outputs to a serializer. A counter is input by the adding circuit and downcounted by the seralizer, one pulse at a time. The decoded contents of the counter after each decrement is output to scalers.

Can multilayer brain networks be a real step forward?. Comment on "Network science of biological systems at different scales: A review" by M. Gosak et al.

NASA Astrophysics Data System (ADS)

Buldú, Javier M.; Papo, David

2018-03-01

Over the last two decades Network Science has become one of the most active fields in science, whose growth has been supported by four fundamental pillars: statistical physics, nonlinear dynamics, graph theory and Big Data [1]. Initially concerned with analyzing the structure of networks, Network Science rapidly turned its attention, focused on the implications of network topology, on the dynamics of and processes unfolding on networked systems, greatly improving our understanding of diffusion, synchronization, epidemics and information transmission in complex systems [2]. The network approach typically considered complex systems as evolving in a vacuum; however real networks are generally not isolated systems, but are in continuous and evolving contact with other networks, with which they interact in multiple qualitative different and typically time-varying ways. These systems can then be represented as a collection of subsystems with connectivity layers, which are simply collapsed when considering the traditional monolayer representation. Surprisingly, such an "unpacking" of layers has proven to bear profound consequences on the structural and dynamical properties of networks, leading for instance to counter-intuitive synchronization phenomena, where maximization synchronization is achieved through strategies opposite of those maximizing synchronization in isolated networks [3].

Hardware Timestamping for an Image Acquisition System Based on FlexRIO and IEEE 1588 v2 Standard

NASA Astrophysics Data System (ADS)

Esquembri, S.; Sanz, D.; Barrera, E.; Ruiz, M.; Bustos, A.; Vega, J.; Castro, R.

2016-02-01

Current fusion devices usually implement distributed acquisition systems for the multiple diagnostics of their experiments. However, each diagnostic is composed by hundreds or even thousands of signals, including images from the vessel interior. These signals and images must be correctly timestamped, because all the information will be analyzed to identify plasma behavior using temporal correlations. For acquisition devices without synchronization mechanisms the timestamp is given by another device with timing capabilities when signaled by the first device. Later, each data should be related with its timestamp, usually via software. This critical action is unfeasible for software applications when sampling rates are high. In order to solve this problem this paper presents the implementation of an image acquisition system with real-time hardware timestamping mechanism. This is synchronized with a master clock using the IEEE 1588 v2 Precision Time Protocol (PTP). Synchronization, image acquisition and processing, and timestamping mechanisms are implemented using Field Programmable Gate Array (FPGA) and a timing card -PTP v2 synchronized. The system has been validated using a camera simulator streaming videos from fusion databases. The developed architecture is fully compatible with ITER Fast Controllers and has been integrated with EPICS to control and monitor the whole system.

Phase locking and multiple oscillating attractors for the coupled mammalian clock and cell cycle

PubMed Central

Feillet, Céline; Krusche, Peter; Tamanini, Filippo; Janssens, Roel C.; Downey, Mike J.; Martin, Patrick; Teboul, Michèle; Saito, Shoko; Lévi, Francis A.; Bretschneider, Till; van der Horst, Gijsbertus T. J.; Delaunay, Franck; Rand, David A.

2014-01-01

Daily synchronous rhythms of cell division at the tissue or organism level are observed in many species and suggest that the circadian clock and cell cycle oscillators are coupled. For mammals, despite known mechanistic interactions, the effect of such coupling on clock and cell cycle progression, and hence its biological relevance, is not understood. In particular, we do not know how the temporal organization of cell division at the single-cell level produces this daily rhythm at the tissue level. Here we use multispectral imaging of single live cells, computational methods, and mathematical modeling to address this question in proliferating mouse fibroblasts. We show that in unsynchronized cells the cell cycle and circadian clock robustly phase lock each other in a 1:1 fashion so that in an expanding cell population the two oscillators oscillate in a synchronized way with a common frequency. Dexamethasone-induced synchronization reveals additional clock states. As well as the low-period phase-locked state there are distinct coexisting states with a significantly higher period clock. Cells transition to these states after dexamethasone synchronization. The temporal coordination of cell division by phase locking to the clock at a single-cell level has significant implications because disordered circadian function is increasingly being linked to the pathogenesis of many diseases, including cancer. PMID:24958884

Phase locking and multiple oscillating attractors for the coupled mammalian clock and cell cycle.

PubMed

Feillet, Céline; Krusche, Peter; Tamanini, Filippo; Janssens, Roel C; Downey, Mike J; Martin, Patrick; Teboul, Michèle; Saito, Shoko; Lévi, Francis A; Bretschneider, Till; van der Horst, Gijsbertus T J; Delaunay, Franck; Rand, David A

2014-07-08

Daily synchronous rhythms of cell division at the tissue or organism level are observed in many species and suggest that the circadian clock and cell cycle oscillators are coupled. For mammals, despite known mechanistic interactions, the effect of such coupling on clock and cell cycle progression, and hence its biological relevance, is not understood. In particular, we do not know how the temporal organization of cell division at the single-cell level produces this daily rhythm at the tissue level. Here we use multispectral imaging of single live cells, computational methods, and mathematical modeling to address this question in proliferating mouse fibroblasts. We show that in unsynchronized cells the cell cycle and circadian clock robustly phase lock each other in a 1:1 fashion so that in an expanding cell population the two oscillators oscillate in a synchronized way with a common frequency. Dexamethasone-induced synchronization reveals additional clock states. As well as the low-period phase-locked state there are distinct coexisting states with a significantly higher period clock. Cells transition to these states after dexamethasone synchronization. The temporal coordination of cell division by phase locking to the clock at a single-cell level has significant implications because disordered circadian function is increasingly being linked to the pathogenesis of many diseases, including cancer.

Pancreatic mixed serous neuroendocrine neoplasm with clear cells leading to diagnosis of von Hippel Lindau disease.

PubMed

Kakkar, Aanchal; Sharma, Mehar C; Yadav, Rajni; Panwar, Rajesh; Mathur, Sandeep R; Iyer, Venkateswaran K; Sahni, Peush

2016-08-01

Mixed serous neuroendocrine neoplasms are extremely rare tumors that are usually seen in female patients and are often associated with von Hippel Lindau (VHL) disease. We describe the case of a 38-year-old male who presented with complaints of anorexia, weight loss, and abdominal pain. CT abdomen showed a mass in the head of the pancreas, multiple small nodules in the body of pancreas, and bilateral adrenal masses. Fine needle aspiration cytology (FNAC) from the mass showed features of a neuroendocrine tumor, with many of the cells demonstrating abundant clear cytoplasm. Histopathological examination of the pancreaticoduodenectomy specimen showed a mixed serous neuroendocrine neoplasm with two components viz. serous cystadenoma and neuroendocrine tumor (NET) World Health Organization (WHO) grade 2. In addition, he was diagnosed to have bilateral pheochromocytomas and a paraganglioma. The synchronicity of these tumors suggested the possibility of VHL disease. Thus, identification of a NET with clear cells or of a mixed serous neuroendocrine neoplasm should raise suspicion of VHL disease. In a mixed tumor, FNAC may identify only one of the two components. Thorough processing of all pancreatic serous tumors for pathological examination is recommended, as NET may occur as a small nodule within the serous cystadenoma. Copyright © 2016 Elsevier GmbH. All rights reserved.

Emergence of synchronization and regularity in firing patterns in time-varying neural hypernetworks

NASA Astrophysics Data System (ADS)

Rakshit, Sarbendu; Bera, Bidesh K.; Ghosh, Dibakar; Sinha, Sudeshna

2018-05-01

We study synchronization of dynamical systems coupled in time-varying network architectures, composed of two or more network topologies, corresponding to different interaction schemes. As a representative example of this class of time-varying hypernetworks, we consider coupled Hindmarsh-Rose neurons, involving two distinct types of networks, mimicking interactions that occur through the electrical gap junctions and the chemical synapses. Specifically, we consider the connections corresponding to the electrical gap junctions to form a small-world network, while the chemical synaptic interactions form a unidirectional random network. Further, all the connections in the hypernetwork are allowed to change in time, modeling a more realistic neurobiological scenario. We model this time variation by rewiring the links stochastically with a characteristic rewiring frequency f . We find that the coupling strength necessary to achieve complete neuronal synchrony is lower when the links are switched rapidly. Further, the average time required to reach the synchronized state decreases as synaptic coupling strength and/or rewiring frequency increases. To quantify the local stability of complete synchronous state we use the Master Stability Function approach, and for global stability we employ the concept of basin stability. The analytically derived necessary condition for synchrony is in excellent agreement with numerical results. Further we investigate the resilience of the synchronous states with respect to increasing network size, and we find that synchrony can be maintained up to larger network sizes by increasing either synaptic strength or rewiring frequency. Last, we find that time-varying links not only promote complete synchronization, but also have the capacity to change the local dynamics of each single neuron. Specifically, in a window of rewiring frequency and synaptic coupling strength, we observe that the spiking behavior becomes more regular.

EFFECTS OF INTENSE, SHORT DURATION GRAZING ON MICROTOPOGRAPHY IN A CHIHUAHUAN DESERT GRASSLAND

EPA Science Inventory

Microtopography describes variations in soil surface elevation (nim or cm) for a scale of a few meters of horizontal distance, Small-scale (few centimeters) changes in vegetation communities synchronized with the elevation differences were observed in drained marsh (Zedler & Zedl...

Pulsations in the Earth's Lower Ionosphere Synchronized With Solar Flare Emission

NASA Astrophysics Data System (ADS)

Hayes, Laura A.; Gallagher, Peter T.; McCauley, Joseph; Dennis, Brian R.; Ireland, Jack; Inglis, Andrew

2017-10-01

Solar flare emission at X-ray and extreme ultraviolet (EUV) energies can cause substantial enhancements in the electron density in the Earth's lower ionosphere. It has now become clear that flares exhibit quasi-periodic pulsations with timescales of minutes at X-ray energies, but to date, it has not been known if the ionosphere is sensitive to this variability. Here using a combination of very low frequency (24 kHz) measurement together with space-based X-ray and EUV observations, we report pulsations of the ionospheric D region, which are synchronized with a set of pulsating flare loops. Modeling of the ionosphere show that the D region electron density varies by up to an order of magnitude over the timescale of the pulsations (˜ 20 min). Our results reveal that the Earth's ionosphere is more sensitive to small-scale changes in solar soft X-ray flux than previously thought and implies that planetary ionospheres are closely coupled to small-scale changes in solar/stellar activity.

Low-cost compact ECG with graphic LCD and phonocardiogram system design.

PubMed

Kara, Sadik; Kemaloğlu, Semra; Kirbaş, Samil

2006-06-01

Till today, many different ECG devices are made in developing countries. In this study, low cost, small size, portable LCD screen ECG device, and phonocardiograph were designed. With designed system, heart sounds that take synchronously with ECG signal are heard as sensitive. Improved system consist three units; Unit 1, ECG circuit, filter and amplifier structure. Unit 2, heart sound acquisition circuit. Unit 3, microcontroller, graphic LCD and ECG signal sending unit to computer. Our system can be used easily in different departments of the hospital, health institution and clinics, village clinic and also in houses because of its small size structure and other benefits. In this way, it is possible that to see ECG signal and hear heart sounds as synchronously and sensitively. In conclusion, heart sounds are heard on the part of both doctor and patient because sounds are given to environment with a tiny speaker. Thus, the patient knows and hears heart sounds him/herself and is acquainted by doctor about healthy condition.

Operation and Chemotherapy: Prognostic Factors for Lung Cancer With One Synchronous Metastasis.

PubMed

Toffart, Anne-Claire; Duruisseaux, Michaël; Brichon, Pierre-Yves; Pirvu, Augustin; Villa, Julie; Selek, Laurent; Guillem, Pascale; Dumas, Isabelle; Ferrer, Léonie; Levra, Matteo Giaj; Moro-Sibilot, Denis

2018-03-01

Stage IV non-small cell lung cancer (NSCLC) is considered incurable; however, some patients with only few metastases may benefit from treatment with a curative intent. We aimed to identify the prognostic factors for stage IV NSCLC with synchronous solitary M1. A database constructed from our weekly multidisciplinary thoracic oncology meetings was retrospectively screened from 1993 to 2012. Consecutive patients with NSCLC stages I to IV were included. Of the 6,760 patients found, 4,832 patients were studied. Among the 1,592 patients (33%) with stage IV NSCLC, 109 (7%) had a synchronous solitary M1. Metastasis involved the brain in 64% of patients. Median overall survival was significantly longer in synchronous solitary M1 than in other stage IV (18.9 months, interquartile range [IQR]: 9.9 to 34.6 months versus 6.1 months, IQR: 2.3 to 13.7 months], respectively, p < 10 -4 ). Among patients with synchronous solitary M1, 90 (83%) received a local treatment with curative intent at the primary and metastatic sites. Factors independently associated with survival were age older than 63 years (hazard ratio [HR] 1.63, 95% confidence interval [CI]: 1.01 to 2.63), Performance status of 3 or 4 (HR 7.91, 95% CI: 2.23 to 28.03), use of chemotherapy (HR 0.38, 95% CI: 0.23 to 0.64), and operation conducted at both sites (HR 0.35, 95% CI: 0.19 to 0.65). Synchronous solitary M1 treated with chemotherapy and operation at both sites resulted in better survival. Survival of NSCLC with synchronous solitary M1 was more similar to stage III than other stage IV NSCLCs. The eighth TNM classification takes this into account by distinguishing between stages M1b and M1c. Copyright © 2018 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Do Porpoises Choose Their Associates? A New Method for Analyzing Social Relationships among Cetaceans

PubMed Central

Sakai, Mai; Wang, Ding; Wang, Kexiong; Li, Songhai; Akamatsu, Tomonari

2011-01-01

Background Observing and monitoring the underwater social interactions of cetaceans is challenging. Therefore, previous cetacean studies have monitored these interactions by surface observations. However, because cetaceans spend most of their time underwater, it is important that their underwater behavior is also continuously monitored to better understand their social relationships and social structure. The finless porpoise is small and has no dorsal fin. It is difficult to observe this species in the wild, and little is known of its sociality. Methodology/Principal Findings The swim depths of 6 free-ranging finless porpoises were simultaneously recorded using a time-synchronized bio-logging system. Synchronous diving was used as an index of association. Two pairs, #27 (an immature female estimated to be 3.5 years old) and #32 (an adult male), #28 (a juvenile male estimated to be 2 years old) and #29 (an adult male), tended to participate in long periods of synchronized diving more frequently than 13 other possible pairs, indicating that the 4 porpoises chose their social partners. The adult males (#32, #29) tended to follow the immature female (#27) and juvenile male (#28), respectively. However, during synchronized diving, the role of an initiator often changed within the pair, and their body movements appeared to be non-agonistic, e.g., rubbing of bodies against one another instead of that on one-side, as observed with chasing and escaping behaviors. Conclusions/Significance The present study employed a time-synchronized bio-logging method to observe the social relationships of free-ranging aquatic animals based on swimming depth. The results suggest that certain individuals form associations even if they are not a mother and calf pair. Long synchronized dives occurred when particular members were reunited, and this suggests that the synchronized dives were not a by-product of opportunistic aggregation. PMID:22216123

A Dual-Intein Autoprocessing Domain that Directs Synchronized Protein Co-Expression in Both Prokaryotes and Eukaryotes

PubMed Central

Zhang, Bei; Rapolu, Madhusudhan; Liang, Zhibin; Han, Zhenlin; Williams, Philip G.; Su, Wei Wen

2015-01-01

Being able to coordinate co-expression of multiple proteins is necessary for a variety of important applications such as assembly of protein complexes, trait stacking, and metabolic engineering. Currently only few options are available for multiple recombinant protein co-expression, and most of them are not applicable to both prokaryotic and eukaryotic hosts. Here, we report a new polyprotein vector system that is based on a pair of self-excising mini-inteins fused in tandem, termed the dual-intein (DI) domain, to achieve synchronized co-expression of multiple proteins. The DI domain comprises an Ssp DnaE mini-intein N159A mutant and an Ssp DnaB mini-intein C1A mutant connected in tandem by a peptide linker to mediate efficient release of the flanking proteins via autocatalytic cleavage. Essentially complete release of constituent proteins, GFP and RFP (mCherry), from a polyprotein precursor, in bacterial, mammalian, and plant hosts was demonstrated. In addition, successful co-expression of GFP with chloramphenicol acetyltransferase, and thioredoxin with RFP, respectively, further substantiates the general applicability of the DI polyprotein system. Collectively, our results demonstrate the DI-based polyprotein technology as a highly valuable addition to the molecular toolbox for multi-protein co-expression which finds vast applications in biotechnology, biosciences, and biomedicine. PMID:25712612

A Two-Phase Time Synchronization-Free Localization Algorithm for Underwater Sensor Networks.

PubMed

Luo, Junhai; Fan, Liying

2017-03-30

Underwater Sensor Networks (UWSNs) can enable a broad range of applications such as resource monitoring, disaster prevention, and navigation-assistance. Sensor nodes location in UWSNs is an especially relevant topic. Global Positioning System (GPS) information is not suitable for use in UWSNs because of the underwater propagation problems. Hence, some localization algorithms based on the precise time synchronization between sensor nodes that have been proposed for UWSNs are not feasible. In this paper, we propose a localization algorithm called Two-Phase Time Synchronization-Free Localization Algorithm (TP-TSFLA). TP-TSFLA contains two phases, namely, range-based estimation phase and range-free evaluation phase. In the first phase, we address a time synchronization-free localization scheme based on the Particle Swarm Optimization (PSO) algorithm to obtain the coordinates of the unknown sensor nodes. In the second phase, we propose a Circle-based Range-Free Localization Algorithm (CRFLA) to locate the unlocalized sensor nodes which cannot obtain the location information through the first phase. In the second phase, sensor nodes which are localized in the first phase act as the new anchor nodes to help realize localization. Hence, in this algorithm, we use a small number of mobile beacons to help obtain the location information without any other anchor nodes. Besides, to improve the precision of the range-free method, an extension of CRFLA achieved by designing a coordinate adjustment scheme is updated. The simulation results show that TP-TSFLA can achieve a relative high localization ratio without time synchronization.

A Two-Phase Time Synchronization-Free Localization Algorithm for Underwater Sensor Networks

PubMed Central

Luo, Junhai; Fan, Liying

2017-01-01

Underwater Sensor Networks (UWSNs) can enable a broad range of applications such as resource monitoring, disaster prevention, and navigation-assistance. Sensor nodes location in UWSNs is an especially relevant topic. Global Positioning System (GPS) information is not suitable for use in UWSNs because of the underwater propagation problems. Hence, some localization algorithms based on the precise time synchronization between sensor nodes that have been proposed for UWSNs are not feasible. In this paper, we propose a localization algorithm called Two-Phase Time Synchronization-Free Localization Algorithm (TP-TSFLA). TP-TSFLA contains two phases, namely, range-based estimation phase and range-free evaluation phase. In the first phase, we address a time synchronization-free localization scheme based on the Particle Swarm Optimization (PSO) algorithm to obtain the coordinates of the unknown sensor nodes. In the second phase, we propose a Circle-based Range-Free Localization Algorithm (CRFLA) to locate the unlocalized sensor nodes which cannot obtain the location information through the first phase. In the second phase, sensor nodes which are localized in the first phase act as the new anchor nodes to help realize localization. Hence, in this algorithm, we use a small number of mobile beacons to help obtain the location information without any other anchor nodes. Besides, to improve the precision of the range-free method, an extension of CRFLA achieved by designing a coordinate adjustment scheme is updated. The simulation results show that TP-TSFLA can achieve a relative high localization ratio without time synchronization. PMID:28358342

Effect of spike-timing-dependent plasticity on stochastic burst synchronization in a scale-free neuronal network.

PubMed

Kim, Sang-Yoon; Lim, Woochang

2018-06-01

We consider an excitatory population of subthreshold Izhikevich neurons which cannot fire spontaneously without noise. As the coupling strength passes a threshold, individual neurons exhibit noise-induced burstings. This neuronal population has adaptive dynamic synaptic strengths governed by the spike-timing-dependent plasticity (STDP). However, STDP was not considered in previous works on stochastic burst synchronization (SBS) between noise-induced burstings of sub-threshold neurons. Here, we study the effect of additive STDP on SBS by varying the noise intensity D in the Barabási-Albert scale-free network (SFN). One of our main findings is a Matthew effect in synaptic plasticity which occurs due to a positive feedback process. Good burst synchronization (with higher bursting measure) gets better via long-term potentiation (LTP) of synaptic strengths, while bad burst synchronization (with lower bursting measure) gets worse via long-term depression (LTD). Consequently, a step-like rapid transition to SBS occurs by changing D , in contrast to a relatively smooth transition in the absence of STDP. We also investigate the effects of network architecture on SBS by varying the symmetric attachment degree [Formula: see text] and the asymmetry parameter [Formula: see text] in the SFN, and Matthew effects are also found to occur by varying [Formula: see text] and [Formula: see text]. Furthermore, emergences of LTP and LTD of synaptic strengths are investigated in details via our own microscopic methods based on both the distributions of time delays between the burst onset times of the pre- and the post-synaptic neurons and the pair-correlations between the pre- and the post-synaptic instantaneous individual burst rates (IIBRs). Finally, a multiplicative STDP case (depending on states) with soft bounds is also investigated in comparison with the additive STDP case (independent of states) with hard bounds. Due to the soft bounds, a Matthew effect with some quantitative differences is also found to occur for the case of multiplicative STDP.

The behavior of multiple independent managers and ecological traits interact to determine prevalence of weeds.

PubMed

Coutts, Shaun R; Yokomizo, Hiroyuki; Buckley, Yvonne M

2013-04-01

Management of damaging invasive plants is often undertaken by multiple decision makers, each managing only a small part of the invader's population. As weeds can move between properties and re-infest eradicated sites from unmanaged sources, the dynamics of multiple decision makers plays a significant role in weed prevalence and invasion risk at the landscape scale. We used a spatially explicit agent-based simulation to determine how individual agent behavior, in concert with weed population ecology, determined weed prevalence. We compared two invasive grass species that differ in ecology, control methods, and costs: Nassella trichotoma (serrated tussock) and Eragrostis curvula (African love grass). The way decision makers reacted to the benefit of management had a large effect on the extent of a weed. If benefits of weed control outweighed the costs, and either net benefit was very large or all agents were very sensitive to net benefits, then agents tended to act synchronously, reducing the pool of infested agents available to spread the weed. As N. trichotoma was more damaging than E. curvula and had more effective control methods, agents chose to manage it more often, which resulted in lower prevalence of N. trichotoma. A relatively low number of agents who were intrinsically less motivated to control weeds led to increased prevalence of both species. This was particularly apparent when long-distance dispersal meant each infested agent increased the invasion risk for a large portion of the landscape. In this case, a small proportion of land mangers reluctant to control, regardless of costs and benefits, could lead to the whole landscape being infested, even when local control stopped new infestations. Social pressure was important, but only if it was independent of weed prevalence, suggesting that early access to information, and incentives to act on that information, may be crucial in stopping a weed from infesting large areas. The response of our model to both behavioral and ecological parameters was highly nonlinear. This implies that the outcomes of weed management programs that deal with multiple land mangers could be highly variable in both space and through time.

Subthalamic stimulation modulates cortical motor network activity and synchronization in Parkinson's disease.

PubMed

Weiss, Daniel; Klotz, Rosa; Govindan, Rathinaswamy B; Scholten, Marlieke; Naros, Georgios; Ramos-Murguialday, Ander; Bunjes, Friedemann; Meisner, Christoph; Plewnia, Christian; Krüger, Rejko; Gharabaghi, Alireza

2015-03-01

Dynamic modulations of large-scale network activity and synchronization are inherent to a broad spectrum of cognitive processes and are disturbed in neuropsychiatric conditions including Parkinson's disease. Here, we set out to address the motor network activity and synchronization in Parkinson's disease and its modulation with subthalamic stimulation. To this end, 20 patients with idiopathic Parkinson's disease with subthalamic nucleus stimulation were analysed on externally cued right hand finger movements with 1.5-s interstimulus interval. Simultaneous recordings were obtained from electromyography on antagonistic muscles (right flexor digitorum and extensor digitorum) together with 64-channel electroencephalography. Time-frequency event-related spectral perturbations were assessed to determine cortical and muscular activity. Next, cross-spectra in the time-frequency domain were analysed to explore the cortico-cortical synchronization. The time-frequency modulations enabled us to select a time-frequency range relevant for motor processing. On these time-frequency windows, we developed an extension of the phase synchronization index to quantify the global cortico-cortical synchronization and to obtain topographic differentiations of distinct electrode sites with respect to their contributions to the global phase synchronization index. The spectral measures were used to predict clinical and reaction time outcome using regression analysis. We found that movement-related desynchronization of cortical activity in the upper alpha and beta range was significantly facilitated with 'stimulation on' compared to 'stimulation off' on electrodes over the bilateral parietal, sensorimotor, premotor, supplementary-motor, and prefrontal areas, including the bilateral inferior prefrontal areas. These spectral modulations enabled us to predict both clinical and reaction time improvement from subthalamic stimulation. With 'stimulation on', interhemispheric cortico-cortical coherence in the beta band was significantly attenuated over the bilateral sensorimotor areas. Similarly, the global cortico-cortical phase synchronization was attenuated, and the topographic differentiation revealed stronger desynchronization over the (ipsilateral) right-hemispheric prefrontal, premotor and sensorimotor areas compared to 'stimulation off'. We further demonstrated that the cortico-cortical phase synchronization was largely dominated by genuine neuronal coupling. The clinical improvement with 'stimulation on' compared to 'stimulation off' could be predicted from this cortical decoupling with multiple regressions, and the reduction of synchronization over the right prefrontal area showed a linear univariate correlation with clinical improvement. Our study demonstrates wide-spread activity and synchronization modulations of the cortical motor network, and highlights subthalamic stimulation as a network-modulating therapy. Accordingly, subthalamic stimulation may release bilateral cortical computational resources by facilitating movement-related desynchronization. Moreover, the subthalamic nucleus is critical to balance inhibitory and facilitatory cortical players within the motor program. © The Author (2015). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Subthalamic stimulation modulates cortical motor network activity and synchronization in Parkinson’s disease

PubMed Central

Klotz, Rosa; Govindan, Rathinaswamy B.; Scholten, Marlieke; Naros, Georgios; Ramos-Murguialday, Ander; Bunjes, Friedemann; Meisner, Christoph; Plewnia, Christian; Krüger, Rejko

2015-01-01

Dynamic modulations of large-scale network activity and synchronization are inherent to a broad spectrum of cognitive processes and are disturbed in neuropsychiatric conditions including Parkinson’s disease. Here, we set out to address the motor network activity and synchronization in Parkinson’s disease and its modulation with subthalamic stimulation. To this end, 20 patients with idiopathic Parkinson’s disease with subthalamic nucleus stimulation were analysed on externally cued right hand finger movements with 1.5-s interstimulus interval. Simultaneous recordings were obtained from electromyography on antagonistic muscles (right flexor digitorum and extensor digitorum) together with 64-channel electroencephalography. Time-frequency event-related spectral perturbations were assessed to determine cortical and muscular activity. Next, cross-spectra in the time-frequency domain were analysed to explore the cortico-cortical synchronization. The time-frequency modulations enabled us to select a time-frequency range relevant for motor processing. On these time-frequency windows, we developed an extension of the phase synchronization index to quantify the global cortico-cortical synchronization and to obtain topographic differentiations of distinct electrode sites with respect to their contributions to the global phase synchronization index. The spectral measures were used to predict clinical and reaction time outcome using regression analysis. We found that movement-related desynchronization of cortical activity in the upper alpha and beta range was significantly facilitated with ‘stimulation on’ compared to ‘stimulation off’ on electrodes over the bilateral parietal, sensorimotor, premotor, supplementary-motor, and prefrontal areas, including the bilateral inferior prefrontal areas. These spectral modulations enabled us to predict both clinical and reaction time improvement from subthalamic stimulation. With ‘stimulation on’, interhemispheric cortico-cortical coherence in the beta band was significantly attenuated over the bilateral sensorimotor areas. Similarly, the global cortico-cortical phase synchronization was attenuated, and the topographic differentiation revealed stronger desynchronization over the (ipsilateral) right-hemispheric prefrontal, premotor and sensorimotor areas compared to ‘stimulation off’. We further demonstrated that the cortico-cortical phase synchronization was largely dominated by genuine neuronal coupling. The clinical improvement with ‘stimulation on’ compared to ‘stimulation off’ could be predicted from this cortical decoupling with multiple regressions, and the reduction of synchronization over the right prefrontal area showed a linear univariate correlation with clinical improvement. Our study demonstrates wide-spread activity and synchronization modulations of the cortical motor network, and highlights subthalamic stimulation as a network-modulating therapy. Accordingly, subthalamic stimulation may release bilateral cortical computational resources by facilitating movement-related desynchronization. Moreover, the subthalamic nucleus is critical to balance inhibitory and facilitatory cortical players within the motor program. PMID:25558877

Studies of ambient noise in shallow water environments off Mexico and Alaska: characteristics, metrics and time-synchronization applications

NASA Astrophysics Data System (ADS)

Guerra, Melania

Sound in the ocean originates from multiple mechanisms, both natural and anthropogenic. Collectively, underwater ambient noise accumulates valuable information about both its sources and the oceanic environment that propagates this noise. Characterizing the features of ambient noise source mechanisms is challenging, but essential, for properly describing an acoustic environment. Disturbances to a local acoustic environment may affect many aquatic species that have adapted to be heavily dependent on this particular sense for survival functions. In the case of marine mammals, which are federally protected, demand exists for understanding such potential impacts, which drives important scientific efforts that utilize passive acoustic monitoring (PAM) tools to inform regulatory decisions. This dissertation presents two independent studies that use PAM data to investigate the characteristics of source mechanisms that dominate ambient noise in two diverse shallow water environments. The study in Chapter 2 directly addresses the concern of how anthropogenic activities can degrade the effectiveness of PAM. In the Alaskan Beaufort Sea, an environment where ambient noise is normally dominated by natural causes, seismic surveys create impulsive sounds to map the composition of the bottom. By inspecting single-sensor PAM data, the spectral characteristics of seismic survey airgun reverberation are measured, and their contribution to the overall ambient noise is quantified. This work is relevant to multiple ongoing mitigation protocols that rely on PAM to acoustically detect marine mammal presence during industrial operations. Meanwhile, Chapter 3 demonstrates that by analyzing data from multiple PAM sensors, features embedded in both directional and omnidirectional ambient noise can be used to develop new time-synchronization processing techniques for aligning autonomous elements of an acoustic array, a tool commonly used in PAM for detecting and tracking marine mammals. Using the time-synchronization procedures shown here, arrays may be built out of stand-alone recorders that simplify the deployment logistics and can be arranged in multiple configurations. Given increasing economic pressures worldwide, anthropogenic activities in the ocean are only expected to expand, and their ambient noise contributions will continue to rise. These studies provide baseline knowledge and practical tools to help properly assess the impact of such source mechanisms in shallow-water acoustic environments.

Autonomous and driven dynamics of spin torque nano-oscillators

NASA Astrophysics Data System (ADS)

Urazhdin, Sergei

2012-02-01

Understanding the dynamical properties of autonomous spin torque nano-oscillators (STNO) and their response to external perturbations is important for their applications as nanoscale microwave sources. We used spectroscopic measurements to study the dynamical characteristics of nanopillar- and point contact-based STNOs incorporating a microstrip in close proximity to the active magnetic layer. By applying microwave current at frequency fext to the microstrip, we were able to generate large microwave fields of more than 30 Oe rms at the location of STNO. We demonstrate that for a wide range of fext, STNO exhibits multiple synchronization regimes with integer and non-integer rational ratios between fext and the oscillation frequency f. We show that the synchronization ranges are determined by the symmetry of the oscillation orbit and the orientation of the driving field relative to the symmetry axis of the orbit. We observe synchronization hysteresis, i.e. a dependence of the synchronization limits on the dynamical history caused by the nonlinearity of STNO. We also show that the oscillation can be parametrically excited in the subcritical regime of STNO by a microwave field at twice the frequency of the oscillation. By measuring the threshold and the frequency range of parametric excitation, we determine damping, spin-polarization efficiency, and coupling to the microwave signal. In addition, by measuring the frequency range of parametric synchronization in the auto-oscillation regime, we determine the dynamic nonlinearity of the nanomagnet. Thus, analysis of the driven oscillations provides complete information about the dynamical characteristics of STNO. Finally, we discuss several unusual dynamical behaviors of STNO caused by their strong nonlinearity.

Balancing Contention and Synchronization on the Intel Paragon

NASA Technical Reports Server (NTRS)

Bokhari, Shahid H.; Nicol, David M.

1996-01-01

The Intel Paragon is a mesh-connected distributed memory parallel computer. It uses an oblivious and deterministic message routing algorithm: this permits us to develop highly optimized schedules for frequently needed communication patterns. The complete exchange is one such pattern. Several approaches are available for carrying it out on the mesh. We study an algorithm developed by Scott. This algorithm assumes that a communication link can carry one message at a time and that a node can only transmit one message at a time. It requires global synchronization to enforce a schedule of transmissions. Unfortunately global synchronization has substantial overhead on the Paragon. At the same time the powerful interconnection mechanism of this machine permits 2 or 3 messages to share a communication link with minor overhead. It can also overlap multiple message transmission from the same node to some extent. We develop a generalization of Scott's algorithm that executes complete exchange with a prescribed contention. Schedules that incur greater contention require fewer synchronization steps. This permits us to tradeoff contention against synchronization overhead. We describe the performance of this algorithm and compare it with Scott's original algorithm as well as with a naive algorithm that does not take interconnection structure into account. The Bounded contention algorithm is always better than Scott's algorithm and outperforms the naive algorithm for all but the smallest message sizes. The naive algorithm fails to work on meshes larger than 12 x 12. These results show that due consideration of processor interconnect and machine performance parameters is necessary to obtain peak performance from the Paragon and its successor mesh machines.

Formal Multilevel Hierarchical Verification of Synchronous MOS VLSI Circuits.

DTIC Science & Technology

1987-06-01

166 12.4 Capacitance Coupling............................. 166 12.5 Multiple Abstraction Fuctions ....................... 168...depend on whether it is performing flat verification or hierarchical verification. The primary operations of Silica Pithecus when performing flat...signals never arise. The primary operation of Silica Pithecus when performing hierarchical verification is processing constraints to show they hold

Development of a Ranging System for the Forward Scattering Meteor Radio Echo Observation Using a GPS-Synchronized Multiple Receiving Stations

NASA Astrophysics Data System (ADS)

Usui, T.; Yoshida, H.; Miyamoto, H.; Yaguchi, N.; Terasawa, T.; Yoshikawa, I.

2012-05-01

We are developing an instrument for teaching purpose to determine the trajectory of a meteor with the Ham-band Radio Observations(HRO) . In this work, we describe newly developed ranging system with using Frequency Modulated signals and show some results.

Are bark beetle outbreaks less synchronous than forest Lepidoptera outbreaks?

Treesearch

Bjorn Okland; Andrew M. Liebhold; Ottar N. Bjornstad; Nadir Erbilgin; Paal Krokene; Paal Krokene

2005-01-01

Comparisons of intraspecific spatial synchrony across multiple epidemic insect species can be useful for generating hypotheses about major determinants of population patterns at larger scales. The present study compares patterns of spatial synchrony in outbreaks of six epidemic bark beetle species in North America and Europe. Spatial synchrony among populations of the...

A comparison of forest canopy transmittance estimators

Treesearch

E.R. Smith; Kurt H. Riitters

1994-01-01

Multiple sensors, and alternate statistical estimators, were tested for measuring canopy transmittance in four stands under a variety of sky conditions. On a given day, stand average transmittance estimates were insensitive to degree of synchronization of the sensors used to measure under-canopy and incoming radiation. In comparisons to periodic measurement of incoming...

Planning and Second Language Development in Task-Based Synchronous Computer-Mediated Communication

ERIC Educational Resources Information Center

Hsu, Hsiu-Chen

2012-01-01

This dissertation explored the effect of two planning conditions (the multiple planning condition with rehearsal and online planning time, and the single planning condition with online planning time only) on L2 production complexity and accuracy and the subsequent development of these two linguistic areas in the context of written synchronous…

Rethinking cell-cycle-dependent gene expression in Schizosaccharomyces pombe.

PubMed

Cooper, Stephen

2017-11-01

Three studies of gene expression during the division cycle of Schizosaccharomyces pombe led to the proposal that a large number of genes are expressed at particular times during the S. pombe cell cycle. Yet only a small fraction of genes proposed to be expressed in a cell-cycle-dependent manner are reproducible in all three published studies. In addition to reproducibility problems, questions about expression amplitudes, cell-cycle timing of expression, synchronization artifacts, and the problem with methods for synchronizing cells must be considered. These problems and complications prompt the idea that caution should be used before accepting the conclusion that there are a large number of genes expressed in a cell-cycle-dependent manner in S. pombe.

Multiple layers of posttranslational regulation refine circadian clock activity in Arabidopsis.

PubMed

Seo, Pil Joon; Mas, Paloma

2014-01-01

The circadian clock is a cellular time-keeper mechanism that regulates biological rhythms with a period of ~24 h. The circadian rhythms in metabolism, physiology, and development are synchronized by environmental cues such as light and temperature. In plants, proper matching of the internal circadian time with the external environment confers fitness advantages on plant survival and propagation. Accordingly, plants have evolved elaborated regulatory mechanisms that precisely control the circadian oscillations. Transcriptional feedback regulation of several clock components has been well characterized over the past years. However, the importance of additional regulatory mechanisms such as chromatin remodeling, protein complexes, protein phosphorylation, and stability is only starting to emerge. The multiple layers of circadian regulation enable plants to properly synchronize with the environmental cycles and to fine-tune the circadian oscillations. This review focuses on the diverse posttranslational events that regulate circadian clock function. We discuss the mechanistic insights explaining how plants articulate a high degree of complexity in their regulatory networks to maintain circadian homeostasis and to generate highly precise waveforms of circadian expression and activity.

Selection of G1 Phase Yeast Cells for Synchronous Meiosis and Sporulation.

PubMed

Stuart, David T

2017-01-01

Centrifugal elutriation is a procedure that allows the fractionation of cell populations based upon their size and shape. This allows cells in distinct cell cycle stages can be captured from an asynchronous population. The technique is particularly helpful when performing an experiment to monitor the progression of cells through the cell cycle or meiosis. Yeast sporulation like gametogenesis in other eukaryotes initiates from the G1 phase of the cell cycle. Conveniently, S. cerevisiae arrest in G1 phase when starved for nutrients and so withdrawal of nitrogen and glucose allows cells to abandon vegetative growth in G1 phase before initiating the sporulation program. This simple starvation protocol yields a partial synchronization that has been used extensively in studies of progression through meiosis and sporulation. By using centrifugal elutriation it is possible to isolate a homogeneous population of G1 phase cells and induce them to sporulate synchronously, which is beneficial for investigating progression through meiosis and sporulation. An additionally benefit of this protocol is that cell populations can be isolated based upon size and both large and small cell populations can be tested for progression through meiosis and sporulation. Here we present a protocol for purification of G1 phase diploid cells for examining synchronous progression through meiosis and sporulation.

FBMC receiver for multi-user asynchronous transmission on fragmented spectrum

NASA Astrophysics Data System (ADS)

Doré, Jean-Baptiste; Berg, Vincent; Cassiau, Nicolas; Kténas, Dimitri

2014-12-01

Relaxed synchronization and access to fragmented spectrum are considered for future generations of wireless networks. Frequency division multiple access for filter bank multicarrier (FBMC) modulation provides promising performance without strict synchronization requirements contrary to conventional orthogonal frequency division multiplexing (OFDM). The architecture of a FBMC receiver suitable for this scenario is considered. Carrier frequency offset (CFO) compensation is combined with intercarrier interference (ICI) cancellation and performs well under very large frequency offsets. Channel estimation and interpolation had to be adapted and proved effective even for heavily fragmented spectrum usage. Channel equalization can sustain large delay spread. Because all the receiver baseband signal processing functionalities are proposed in the frequency domain, the overall architecture is suitable for multiuser asynchronous transmission on fragmented spectrum.

Theta synchronization networks emerge during human object-place memory encoding.

PubMed

Sato, Naoyuki; Yamaguchi, Yoko

2007-03-26

Recent rodent hippocampus studies have suggested that theta rhythm-dependent neural dynamics ('theta phase precession') is essential for an on-line memory formation. A computational study indicated that the phase precession enables a human object-place association memory with voluntary eye movements, although it is still an open question whether the human brain uses the dynamics. Here we elucidated subsequent memory-correlated activities in human scalp electroencephalography in an object-place association memory designed according the former computational study. Our results successfully demonstrated that subsequent memory recall is characterized by an increase in theta power and coherence, and further, that multiple theta synchronization networks emerge. These findings suggest the human theta dynamics in common with rodents in episodic memory formation.

Quantum CSMA/CD Synchronous Communication Protocol with Entanglement

NASA Astrophysics Data System (ADS)

Zhou, Nanrun; Zeng, Binyang; Gong, Lihua

By utilizing the characteristics of quantum entanglement, a quantum synchronous communication protocol for Carrier Sense Multiple Access with Collision Detection (CSMA/CD) is presented. The proposed protocol divides the link into the busy time and leisure one, where the data frames are sent via classical channels and the distribution of quantum entanglement is supposed to be completed at leisure time and the quantum acknowledge frames are sent via quantum entanglement channels. The time span between two successfully delivered messages can be significantly reduced in this proposed protocol. It is shown that the performance of the CSMA/CD protocol can be improved significantly since the collision can be reduced to a certain extent. The proposed protocol has great significance in quantum communication.

Support of Multidimensional Parallelism in the OpenMP Programming Model

NASA Technical Reports Server (NTRS)

Jin, Hao-Qiang; Jost, Gabriele

2003-01-01

OpenMP is the current standard for shared-memory programming. While providing ease of parallel programming, the OpenMP programming model also has limitations which often effect the scalability of applications. Examples for these limitations are work distribution and point-to-point synchronization among threads. We propose extensions to the OpenMP programming model which allow the user to easily distribute the work in multiple dimensions and synchronize the workflow among the threads. The proposed extensions include four new constructs and the associated runtime library. They do not require changes to the source code and can be implemented based on the existing OpenMP standard. We illustrate the concept in a prototype translator and test with benchmark codes and a cloud modeling code.

Emergence of chimeras through induced multistability

NASA Astrophysics Data System (ADS)

Ujjwal, Sangeeta Rani; Punetha, Nirmal; Prasad, Awadhesh; Ramaswamy, Ramakrishna

2017-03-01

Chimeras, namely coexisting desynchronous and synchronized dynamics, are formed in an ensemble of identically coupled identical chaotic oscillators when the coupling induces multiple stable attractors, and further when the basins of the different attractors are intertwined in a complex manner. When there is coupling-induced multistability, an ensemble of identical chaotic oscillators—with global coupling, or also under the influence of common noise or an external drive (chaotic, periodic, or quasiperiodic)—inevitably exhibits chimeric behavior. Induced multistability in the system leads to the formation of distinct subpopulations, one or more of which support synchronized dynamics, while in others the motion is asynchronous or incoherent. We study the mechanism for the emergence of such chimeric states, and we discuss the generality of our results.

Exponential H ∞ Synchronization of Chaotic Cryptosystems Using an Improved Genetic Algorithm

PubMed Central

Hsiao, Feng-Hsiag

2015-01-01

This paper presents a systematic design methodology for neural-network- (NN-) based secure communications in multiple time-delay chaotic (MTDC) systems with optimal H ∞ performance and cryptography. On the basis of the Improved Genetic Algorithm (IGA), which is demonstrated to have better performance than that of a traditional GA, a model-based fuzzy controller is then synthesized to stabilize the MTDC systems. A fuzzy controller is synthesized to not only realize the exponential synchronization, but also achieve optimal H ∞ performance by minimizing the disturbance attenuation level. Furthermore, the error of the recovered message is stated by using the n-shift cipher and key. Finally, a numerical example with simulations is given to demonstrate the effectiveness of our approach. PMID:26366432

Remote Electronic Examinations: Student Experiences.

ERIC Educational Resources Information Center

Thomas, Peter; Price, Blaine; Paine, Carina; Richards, Mike

2002-01-01

Presents findings from a small-scale experiment investigating the presentation of a synchronous, Web-based remote electronic exam in a distance education course. Discusses student experiences based on a questionnaire; time pressures; technical issues; differences between the structure of an electronic exam and a paper-based exam; and future work,…

A Three-Level Analysis of Collaborative Learning in Dual-Interaction Spaces

ERIC Educational Resources Information Center

Lonchamp, Jacques

2009-01-01

CSCL systems which follow the dual-interaction spaces paradigm support the synchronous construction and discussion of shared artifacts by distributed or colocated small groups of learners. The most recent generic dual-interaction space environments, either model based or component based, can be deeply customized by teachers for supporting…

Contact-free heart rate measurement using multiple video data

NASA Astrophysics Data System (ADS)

Hung, Pang-Chan; Lee, Kual-Zheng; Tsai, Luo-Wei

2013-10-01

In this paper, we propose a contact-free heart rate measurement method by analyzing sequential images of multiple video data. In the proposed method, skin-like pixels are firstly detected from multiple video data for extracting the color features. These color features are synchronized and analyzed by independent component analysis. A representative component is finally selected among these independent component candidates to measure the HR, which achieves under 2% deviation on average compared with a pulse oximeter in the controllable environment. The advantages of the proposed method include: 1) it uses low cost and high accessibility camera device; 2) it eases users' discomfort by utilizing contact-free measurement; and 3) it achieves the low error rate and the high stability by integrating multiple video data.

Modeling Indications of Technology in Planetary Transit Light Curves-Dark-side Illumination

NASA Astrophysics Data System (ADS)

Korpela, Eric J.; Sallmen, Shauna M.; Leystra Greene, Diana

2015-08-01

We analyze potential effects of an extraterrestrial civilization’s use of orbiting mirrors to illuminate the dark side of a synchronously rotating planet on planetary transit light curves. Previous efforts to detect civilizations based on side effects of planetary-scale engineering have focused on structures affecting the host star output (e.g., Dyson spheres). However, younger civilizations are likely to be less advanced in their engineering efforts, yet still capable of sending small spacecraft into orbit. Since M dwarfs are the most common type of star in the solar neighborhood, it seems plausible that many of the nearest habitable planets orbit dim, low-mass M stars, and will be in synchronous rotation. Logically, a civilization evolving on such a planet may be inspired to illuminate their planet’s dark side by placing a single large mirror at the L2 Lagrangian point, or launching a fleet of small thin mirrors into planetary orbit. We briefly examine the requirements and engineering challenges of such a collection of orbiting mirrors, then explore their impact on transit light curves. We incorporate stellar limb darkening and model a simplistic mirror fleet’s effects for transits of Earth-like (R = 0.5 to 2 {R}{Earth}) planets which would be synchronously rotating for orbits within the habitable zone of their host star. Although such an installation is undetectable in Kepler data, the James Webb Space Telescope will provide the sensitivity necessary to detect a fleet of mirrors orbiting Earth-like habitable planets around nearby stars.

A Timer for Synchronous Digital Systems

NASA Technical Reports Server (NTRS)

McKenney, Elizabeth; Irwin, Philip

2003-01-01

The Real-Time Interferometer Control Systems Testbed (RICST) timing board is a VersaModule Eurocard (VME)-based board that can generate up to 16 simultaneous, phase-locked timing signals at a rate defined by the user. It can also generate all seven VME interrupt requests (IRQs). The RICST timing board is suitable mainly for robotic, aerospace, and real-time applications. Several circuit boards on the market are capable of generating periodic IRQs. Most are associated with Global Positioning System (GPS) receivers and Inter Range Instrumentation Group (IRIG) time-code generators, whereas this board uses either an internal VME clock or an externally generated clock signal to synchronize multiple components of the system. The primary advantage of this board is that there is no discernible jitter in the output clock waveforms because the signals are divided down from a high-frequency clock signal instead of being phase-locked from a lower frequency. The primary disadvantage to this board, relative to other periodic-IRQ-generating boards, is that it is more difficult to synchronize the system to wall clock time.

A comprehensive methodology for the multidimensional and synchronic data collecting in soundscape.

PubMed

Kogan, Pablo; Turra, Bruno; Arenas, Jorge P; Hinalaf, María

2017-02-15

The soundscape paradigm is comprised of complex living systems where individuals interact moment-by-moment among one another and with the physical environment. The real environments provide promising conditions to reveal deep soundscape behavior, including the multiple components involved and their interrelations as a whole. However, measuring and analyzing the numerous simultaneous variables of soundscape represents a challenge that is not completely understood. This work proposes and applies a comprehensive methodology for multidimensional and synchronic data collection in soundscape. The soundscape variables were organized into three main entities: experienced environment, acoustic environment, and extra-acoustic environment, containing, in turn, subgroups of variables called components. The variables contained in these components were acquired through synchronic field techniques that include surveys, acoustic measurements, audio recordings, photography, and video. The proposed methodology was tested, optimized, and applied in diverse open environments, including squares, parks, fountains, university campuses, streets, and pedestrian areas. The systematization of this comprehensive methodology provides a framework for soundscape research, a support for urban and environment management, and a preliminary procedure for standardization in soundscape data collecting. Copyright © 2016 Elsevier B.V. All rights reserved.

Weakly and strongly coupled Belousov-Zhabotinsky patterns.

PubMed

Weiss, Stephan; Deegan, Robert D

2017-02-01

We investigate experimentally and numerically the synchronization of two-dimensional spiral wave patterns in the Belousov-Zhabotinsky reaction due to point-to-point coupling of two separate domains. Different synchronization modalities appear depending on the coupling strength and the initial patterns in each domain. The behavior as a function of the coupling strength falls into two qualitatively different regimes. The weakly coupled regime is characterized by inter-domain interactions that distorted but do not break wave fronts. Under weak coupling, spiral cores are pushed around by wave fronts in the other domain, resulting in an effective interaction between cores in opposite domains. In the case where each domain initially contains a single spiral, the cores form a bound pair and orbit each other at quantized distances. When the starting patterns consist of multiple randomly positioned spiral cores, the number of cores decreases with time until all that remains are a few cores that are synchronized with a partner in the other domain. The strongly coupled regime is characterized by interdomain interactions that break wave fronts. As a result, the wave patterns in both domains become identical.

Weakly and strongly coupled Belousov-Zhabotinsky patterns

NASA Astrophysics Data System (ADS)

Weiss, Stephan; Deegan, Robert D.

2017-02-01

We investigate experimentally and numerically the synchronization of two-dimensional spiral wave patterns in the Belousov-Zhabotinsky reaction due to point-to-point coupling of two separate domains. Different synchronization modalities appear depending on the coupling strength and the initial patterns in each domain. The behavior as a function of the coupling strength falls into two qualitatively different regimes. The weakly coupled regime is characterized by inter-domain interactions that distorted but do not break wave fronts. Under weak coupling, spiral cores are pushed around by wave fronts in the other domain, resulting in an effective interaction between cores in opposite domains. In the case where each domain initially contains a single spiral, the cores form a bound pair and orbit each other at quantized distances. When the starting patterns consist of multiple randomly positioned spiral cores, the number of cores decreases with time until all that remains are a few cores that are synchronized with a partner in the other domain. The strongly coupled regime is characterized by interdomain interactions that break wave fronts. As a result, the wave patterns in both domains become identical.

Enhancing the Simulation Speed of Sensor Network Applications by Asynchronization of Interrupt Service Routines

PubMed Central

Joe, Hyunwoo; Woo, Duk-Kyun; Kim, Hyungshin

2013-01-01

Sensor network simulations require high fidelity and timing accuracy to be used as an implementation and evaluation tool. The cycle-accurate and instruction-level simulator is the known solution for these purposes. However, this type of simulation incurs a high computation cost since it has to model not only the instruction level behavior but also the synchronization between multiple sensors for their causality. This paper presents a novel technique that exploits asynchronous simulations of interrupt service routines (ISR). We can avoid the synchronization overheads when the interrupt service routines are simulated without preemption. If the causality errors occur, we devise a rollback procedure to restore the original synchronized simulation. This concept can be extended to any instruction-level sensor network simulator. Evaluation results show our method can enhance the simulation speed up to 52% in the case of our experiments. For applications with longer interrupt service routines and smaller number of preemptions, the speedup becomes greater. In addition, our simulator is 2 to 11 times faster than the well-known sensor network simulator. PMID:23966200

The SPARC_LAB femtosecond synchronization for electron and photon pulsed beams

NASA Astrophysics Data System (ADS)

Bellaveglia, M.; Gallo, A.; Piersanti, L.; Pompili, R.; Gatti, G.; Anania, M. P.; Petrarca, M.; Villa, F.; Chiadroni, E.; Biagioni, A.; Mostacci, A.

2015-05-01

The SPARC LAB complex hosts a 150 MeV electron photo-injector equipped with an undulator for FEL production (SPARC) together with a high power TW laser (FLAME). Recently the synchronization system reached the performance of < 100 fsRMS relative jitter between lasers, electron beam and RF accelerating fields. This matches the requirements for next future experiments: (i) the production of X-rays by means of Thomson scattering (first collisions achieved in 2014) and (ii) the particle driven PWFA experiment by means of multiple electron bunches. We report about the measurements taken during the machine operation using BAMs (Bunch Arrival Monitors) and EOS (Electro-Optical Sampling) system. A new R and D activity concerning the LWFA using the external injection of electron bunches in a plasma generated by the FLAME laser pulse is under design. The upgrade of the synchronization system is under way to guarantee the < 30 fs RMS jitter required specification. It foresees the transition from electrical to optical architecture that mainly affects the reference signal distribution and the time of arrival detection performances. The new system architecture is presented together with the related experimental data.

Coordination of multiple appendages in drag-based swimming.

PubMed

Alben, Silas; Spears, Kevin; Garth, Stephen; Murphy, David; Yen, Jeannette

2010-11-06

Krill are aquatic crustaceans that engage in long distance migrations, either vertically in the water column or horizontally for 10 km (over 200,000 body lengths) per day. Hence efficient locomotory performance is crucial for their survival. We study the swimming kinematics of krill using a combination of experiment and analysis. We quantify the propulsor kinematics for tethered and freely swimming krill in experiments, and find kinematics that are very nearly metachronal. We then formulate a drag coefficient model which compares metachronal, synchronous and intermediate motions for a freely swimming body with two legs. With fixed leg velocity amplitude, metachronal kinematics give the highest average body speed for both linear and quadratic drag laws. The same result holds for five legs with the quadratic drag law. When metachronal kinematics is perturbed towards synchronous kinematics, an analysis shows that the velocity increase on the power stroke is outweighed by the velocity decrease on the recovery stroke. With fixed time-averaged work done by the legs, metachronal kinematics again gives the highest average body speed, although the advantage over synchronous kinematics is reduced.

Hardware Simulations of Spacecraft Attitude Synchronization Using Lyapunov-Based Controllers

NASA Astrophysics Data System (ADS)

Jung, Juno; Park, Sang-Young; Eun, Youngho; Kim, Sung-Woo; Park, Chandeok

2018-04-01

In the near future, space missions with multiple spacecraft are expected to replace traditional missions with a single large spacecraft. These spacecraft formation flying missions generally require precise knowledge of relative position and attitude between neighboring agents. In this study, among the several challenging issues, we focus on the technique to control spacecraft attitude synchronization in formation. We develop a number of nonlinear control schemes based on the Lyapunov stability theorem and considering special situations: full-state feedback control, full-state feedback control with unknown inertia parameters, and output feedback control without angular velocity measurements. All the proposed controllers offer absolute and relative control using reaction wheel assembly for both regulator and tracking problems. In addition to the numerical simulations, an air-bearing-based hardware-in-the-loop (HIL) system is used to verify the proposed control laws in real-time hardware environments. The pointing errors converge to 0.5{°} with numerical simulations and to 2{°} using the HIL system. Consequently, both numerical and hardware simulations confirm the performance of the spacecraft attitude synchronization algorithms developed in this study.

Global Mittag-Leffler stability and synchronization analysis of fractional-order quaternion-valued neural networks with linear threshold neurons.

PubMed

Yang, Xujun; Li, Chuandong; Song, Qiankun; Chen, Jiyang; Huang, Junjian

2018-05-04

This paper talks about the stability and synchronization problems of fractional-order quaternion-valued neural networks (FQVNNs) with linear threshold neurons. On account of the non-commutativity of quaternion multiplication resulting from Hamilton rules, the FQVNN models are separated into four real-valued neural network (RVNN) models. Consequently, the dynamic analysis of FQVNNs can be realized by investigating the real-valued ones. Based on the method of M-matrix, the existence and uniqueness of the equilibrium point of the FQVNNs are obtained without detailed proof. Afterwards, several sufficient criteria ensuring the global Mittag-Leffler stability for the unique equilibrium point of the FQVNNs are derived by applying the Lyapunov direct method, the theory of fractional differential equation, the theory of matrix eigenvalue, and some inequality techniques. In the meanwhile, global Mittag-Leffler synchronization for the drive-response models of the addressed FQVNNs are investigated explicitly. Finally, simulation examples are designed to verify the feasibility and availability of the theoretical results. Copyright © 2018 Elsevier Ltd. All rights reserved.

Ultra-Wideband Transceiver Design and Optimization

NASA Astrophysics Data System (ADS)

Mehra, Ashutosh

The technology landscape has quickly changed over the last few years. Developments in personal area networks, IC technology, DSP processing and bio-medical devices have enabled the integration of short range communication into low cost personal health care solutions. Newer technologies and solutions are being developed to cater to the personal operating space(POS) and body area networks(BAN). Health care is driving towards using multiple sensor and therapeutic nodes inside the POS. Technology has enabled remote patient care where the patient has low cost on-body wearables that allow the patient/physician to access vital signs without the patient physically visiting the clinic. Big semiconductor giants want to move into the wearable health monitor space. Along with the developments in fitness based health wearables, there has been a lot of interest towards developing BAN devices catering to the 'mission-critical' wearables and implants. Hearing aids, EKG monitors, neurostimulators are some examples. This work explores the use of the 802.15 ulta wideband (UWB) standard for designing a radio to operate in the a wireless sensor network in the BAN. The specific application targeted is a hearing aid. However, the design in this work is capable of working in a low power low range application with the ability to have multiple data rates ranging from a few kHz to 10's of MHz. The first radio designed by Marconi using spark-gap transmitters was an impulse radio (IR). The IR UWB technology boasts of low power, low cost, high data rates, multiple channels, simultaneous networking, the ability to carry information through obstacles that more limited bandwidths cannot, and also potentially lower complexity hardware design. The inherent timing accuracy associated with the technology gives UWB transmissions immunity to multipath fading and are hence make them more suitable for a cluttered indoor environment. The key difference with the traditional narrowband transceiver is that instead of using continuous wave (CW) transmission, impulses in time are used. The timing accuracy associated with these impulses require synchronization in time, rather than synchronization in frequency for carrier-based CW systems. A complete fully integrated system is presented in thesis. This work presents a low-power noncoherent IR UWB transceiver operating at 5GHz in 0.13um CMOS. A fully-digital transmitter generates a shaped output pulse of 1GHz 3-dB bandwidth. DLLs provide a PVT-tolerant time-step resolution of 1ns over the entire symbol period and regulate the pulse generator center frequency. The transmitter outputs -31dBm (0.88pJ/pulse at 1Mpulse/s) with a dynamic (energy) efficiency of 16pJ/pulse. The transmit out pulse is FCC part 15 compliant over process voltage and temperature (PVT) variations. The transmitter is semi-compliant with IEEE 802.15.6 and IEEE 802.15.4 standards and will become completely compliant with minor modifications. The receiver presented in this work is a non-coherent energy detect IR UWB receiver. The receiver has an on-chip transformer preceding the LNA, which is followed by a super-regenerative amplifier (SRA), envelope detector, sample-and-holds, and a bank of comparators. The design is SRA based energy-detection receiver. Measured results show a receiver efficiency of 0.32nJ/bit at 20.8Mb/s and operation with inputs as low as -70dBm. The SRA based energy-detection receiver utilizes early/late detection for a two-step baseband synchronization algorithm. An integrated solution to the issue of synchronization is also proposed. The system proposed is capable of synchronization and tracking control. The system in this work utilizes early/late detection for a two-step baseband synchronization algorithm. The algorithm is implemented in Matlab and the time to synchronization is observed to be between 250micros to a few couple of ms. Measurements have also been made using the receiver and manually implementing the algorithm. This work addresses all aspects time synchronization in an IR transceiver. The initial mismatch is addressed by two methods. Beyond the initial synchronization, the system presented in this system is also capable of tracking. This would mean that once the transceiver has been synchronized, the timing generation would continue to track the phase and the frequency changes depending upon crystal drift over time or movement between the receiver and the transmitter. A test was also performed on the complete transceiver system with two radios talking to each other over a highly attenuated wired channel.

Western Wind and Solar Integration Study Phase 3A: Low Levels of Synchronous Generation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miller, Nicholas W.; Leonardi, Bruno; D'Aquila, Robert

The stability of the North American electric power grids under conditions of high penetrations of wind and solar is a significant concern and possible impediment to reaching renewable energy goals. The 33% wind and solar annual energy penetration considered in this study results in substantial changes to the characteristics of the bulk power system. This includes different power flow patterns, different commitment and dispatch of existing synchronous generation, and different dynamic behavior from wind and solar generation. The Western Wind and Solar Integration Study (WWSIS), sponsored by the U.S. Department of Energy, is one of the largest regional solar andmore » wind integration studies to date. In multiple phases, it has explored different aspects of the question: Can we integrate large amounts of wind and solar energy into the electric power system of the West? The work reported here focused on the impact of low levels of synchronous generation on the transient stability performance in one part of the region in which wind generation has displaced synchronous thermal generation under highly stressed, weak system conditions. It is essentially an extension of WWSIS-3. Transient stability, the ability of the power system to maintain synchronism among all elements following disturbances, is a major constraint on operations in many grids, including the western U.S. and Texas systems. These constraints primarily concern the performance of the large-scale bulk power system. But grid-wide stability concerns with high penetrations of wind and solar are still not thoroughly understood. This work focuses on 'traditional' fundamental frequency stability issues, such as maintaining synchronism, frequency, and voltage. The objectives of this study are to better understand the implications of low levels of synchronous generation and a weak grid on overall system performance by: 1) Investigating the Western Interconnection under conditions of both high renewable generation (e.g., wind and solar) and low synchronous generation (e.g., significant coal power plant decommitment or retirement); and 2) Analyzing both the large-scale stability of the Western Interconnection and regional stability issues driven by more geographically dispersed renewable generation interacting with a transmission grid that evolved with large, central station plants at key nodes. As noted above, the work reported here is an extension of the research performed in WWSIS-3.« less

A method to synchronize signals from multiple patient monitoring devices through a single input channel for inclusion in list-mode acquisitions

DOE Office of Scientific and Technical Information (OSTI.GOV)

O’Connor, J. Michael; Pretorius, P. Hendrik; Johnson, Karen

2013-12-15

Purpose: This technical note documents a method that the authors developed for combining a signal to synchronize a patient-monitoring device with a second physiological signal for inclusion into list-mode acquisition. Our specific application requires synchronizing an external patient motion-tracking system with a medical imaging system by multiplexing the tracking input with the ECG input. The authors believe that their methodology can be adapted for use in a variety of medical imaging modalities including single photon emission computed tomography (SPECT) and positron emission tomography (PET). Methods: The authors insert a unique pulse sequence into a single physiological input channel. This sequencemore » is then recorded in the list-mode acquisition along with the R-wave pulse used for ECG gating. The specific form of our pulse sequence allows for recognition of the time point being synchronized even when portions of the pulse sequence are lost due to collisions with R-wave pulses. This was achieved by altering our software used in binning the list-mode data to recognize even a portion of our pulse sequence. Limitations on heart rates at which our pulse sequence could be reliably detected were investigated by simulating the mixing of the two signals as a function of heart rate and time point during the cardiac cycle at which our pulse sequence is mixed with the cardiac signal. Results: The authors have successfully achieved accurate temporal synchronization of our motion-tracking system with acquisition of SPECT projections used in 17 recent clinical research cases. In our simulation analysis the authors determined that synchronization to enable compensation for body and respiratory motion could be achieved for heart rates up to 125 beats-per-minute (bpm). Conclusions: Synchronization of list-mode acquisition with external patient monitoring devices such as those employed in motion-tracking can reliably be achieved using a simple method that can be implemented using minimal external hardware and software modification through a single input channel, while still recording cardiac gating signals.« less

Shoulder Functional Electrical Stimulation During Wheelchair Propulsion in Spinal Cord Injury Subjects.

PubMed

Freixes, Orestes; Fernandez, Sergio Anibal; Gatti, Marcelo Andres; Crespo, Marcos Jose; Olmos, Lisandro Emilio; Russo, Maria Julieta

2017-01-01

Background: Subjects with spinal cord injury (SCI) propel their wheelchairs by generating a different level of muscle activity given their multiple deficits in muscle strength. Exercise training programs seem to be effective in improving wheelchair propulsion capacity. Functional electrical stimulation (FES) therapy is a complementary tool for rehabilitation programs. Objectives : To determine the accuracy of the synchronization between the FES activation and the push phase of the propulsion cycle by using hand pressure sensors that allow anterior deltoids activation when the hand is in contact with the pushrim. Methods: We analyzed 2 subjects, with injuries at C6 American Spinal Injury Association Impairment Scale (AIS) A and T12 AIS A. The stimulation parameters were set for a 30 Hz frequency symmetrical biphasic wave, 300 μs pulse width. Data were collected as participants propelled the wheelchair over a 10-m section of smooth, level vinyl floor. Subjects were evaluated in a motion analysis laboratory (ELITE; BTS, Milan, Italy). Results: Subject 1 showed synchronization between the FES activation and the push phase of 87.5% in the left hand and of 80% in the right hand. Subject 2 showed synchronization of 95.1% in the left and of hand 94.9% in the right hand. Conclusion : Our study determined a high accuracy of a novel FES therapeutic option, showing the synchronization between the electrical stimulation and the push phase of the propulsion cycle.

Preparation and Characterization of Silymarin Synchronized and Sustained Release Dropping Pill.

PubMed

Liu, Zhi-Hong; Li, Xue-Jing; Huang, Ai-Wen; Zhang, Jing; Song, Hong-Tao

2017-01-01

This study aimed to develop a synchronized and sustained-release silymarin dropping pill, and to evaluate its pharmacokinetic characteristics. Polyoxyethylene stearate, glyceryl monostearate, and stearic acid were used to prepare the dropping pills. X-ray powder diffraction, differential scanning calorimetry, and release were used to evaluate its physicochemical properties. The plasma concentration of silybin in beagle dogs after oral administration of silymarin dropping pills and silymarin capsule was determined by RP-HPLC. Synchronized release was achieved with high similarity factor f2 values between every set of two of the five components. Mean plasma concentration-time curves of silymarin after oral administration of dropping pills in beagle dogs were in accordance with first-order absorption and open twocompartment model. The Tmax, Cmax, and AUC0-∞ of dropping pills in beagle dogs were 0.8750±0.13 h, 0.8183±0.07 μg·ml-1, and 2.274±0.90 μg·h·ml-1, respectively. Silymarin dropping pills prolonged in vivo exposure and reduced maximum in vivo concentration, achieving a stable level in the serum. The combination of solid dispersion technique and dropping pill formulation allowed synchronized release of multiple components in herbal medicine, and has potential application in the development of sustained release in herbal medicine. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Drift-free solar sail formations in elliptical Sun-synchronous orbits

NASA Astrophysics Data System (ADS)

Parsay, Khashayar; Schaub, Hanspeter

2017-10-01

To study the spatial and temporal variations of plasma in the highly dynamic environment of the magnetosphere, multiple spacecraft must fly in a formation. The objective for this study is to investigate the feasibility of solar sail formation flying in the Earth-centered, Sun-synchronous orbit regime. The focus of this effort is to enable formation flying for a group of solar sails that maintain a nominally fixed Sun-pointing attitude during formation flight, solely for the purpose of precessing their orbit apse lines Sun-synchronously. A fixed-attitude solar sail formation is motivated by the difficulties in the simultaneous control of orbit and attitude in flying solar sails. First, the secular rates of the orbital elements resulting from the effects of solar radiation pressure (SRP) are determined using averaging theory for a Sun-pointing attitude sail. These averaged rates are used to analytically derive the first-order necessary conditions for a drift-free solar sail formation in Sun-synchronous orbits, assuming a fixed Sun-pointing orientation for each sail in formation. The validity of the first-order necessary conditions are illustrated by designing quasi-periodic relative motions. Next, nonlinear programming is applied to design truly drift-free two-craft solar sail formations. Lastly, analytic expressions are derived to determine the long-term dynamics and sensitivity of the formation with respect to constant attitude errors, uncertainty in orbital elements, and uncertainty in a sail's characteristic acceleration.

Multitasking OS manages a team of processors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ripps, D.L.

1983-07-21

MTOS-68k is a real-time multitasking operating system designed for the popular MC68000 microprocessors. It aproaches task coordination and synchronization in a fashion that matches uniquely the structural simplicity and regularity of the 68000 instruction set. Since in many 68000 applications the speed and power of one CPU are not enough, MTOS-68k has been designed to support multiple processors, as well as multiple tasks. Typically, the devices are tightly coupled single-board computers, that is they share a backplane and parts of global memory.