Sample records for synchrotron source chess

  1. Nuclear Bragg scattering studies in [sup 57]Fe with synchrotron radiation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Haustein, P.E.

    1993-01-01

    Studies of nuclear Bragg x-ray scattering of synchrotron radiation, using crystals of [alpha]-[sup 57]Fe[sub 2]O[sub 3], have been carried out at the NSLS at Brookhaven National Laboratory and at the Cornell University CHESS facility. These studies have demonstrated that nuclear resonance states can be used to produce filtered x-ray beams which have extremely narrow bandwidth, small angular divergence and unique polarization and temporal properties. this combination of characteristics, unobtainable with radioactive sources, makes synchrotron-based Moessbauer spectroscopy feasible and is an important complement to existing methods. A review of the experimental methodology is presented. As well as come suggestions for fullermore » exploitation of this new technique.« less

  2. Nuclear Bragg scattering studies in {sup 57}Fe with synchrotron radiation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Haustein, P.E.

    1993-03-01

    Studies of nuclear Bragg x-ray scattering of synchrotron radiation, using crystals of {alpha}-{sup 57}Fe{sub 2}O{sub 3}, have been carried out at the NSLS at Brookhaven National Laboratory and at the Cornell University CHESS facility. These studies have demonstrated that nuclear resonance states can be used to produce filtered x-ray beams which have extremely narrow bandwidth, small angular divergence and unique polarization and temporal properties. this combination of characteristics, unobtainable with radioactive sources, makes synchrotron-based Moessbauer spectroscopy feasible and is an important complement to existing methods. A review of the experimental methodology is presented. As well as come suggestions for fullermore » exploitation of this new technique.« less

  3. Ultrapressure materials science

    NASA Technical Reports Server (NTRS)

    Ruoff, A. L.

    1984-01-01

    Three active areas of research at ultra pressure are pursued, i.e., diffraction studies with the Cornell High Energy Synchrotron Source (CHESS), band gap and absorption edge effects, indentor-anvil experiments and theory and research to attain higher pressures. The range over which X-ray diffraction data and absorption edge data are obtained is extended to 700 kbars. Using the indentor technique pressures of 2.1 Mbars are obtained. Research results and methods are discussed.

  4. Simulation and Laboratory results of the Hard X-ray Polarimeter: X-Calibur

    NASA Astrophysics Data System (ADS)

    Guo, Qingzhen; Beilicke, M.; Kislat, F.; Krawczynski, H.

    2014-01-01

    X-ray polarimetry promises to give qualitatively new information about high-energy sources, such as binary black hole (BH) systems, Microquasars, active galactic nuclei (AGN), GRBs, etc. We designed, built and tested a hard X-ray polarimeter 'X-Calibur' to be flown in the focal plane of the InFOCuS grazing incidence hard X-ray telescope in 2014. X-Calibur combines a low-Z Compton scatterer with a CZT detector assembly to measure the polarization of 20- 80 keV X-rays making use of the fact that polarized photons Compton scatter preferentially perpendicular to the E field orientation. X-Calibur achieves a high detection efficiency of order unity. We optimized of the design of the instrument based on Monte Carlo simulations of polarized and unpolarized X-ray beams and of the most important background components. We have calibrated and tested X-Calibur extensively in the laboratory at Washington University and at the Cornell High-Energy Synchrotron Source (CHESS). Measurements using the highly polarized synchrotron beam at CHESS confirm the polarization sensitivity of the instrument. In this talk we report on the optimization of the design of the instrument based on Monte Carlo simulations, as well as results of laboratory calibration measurements characterizing the performance of the instrument.

  5. Application of CHESS single-bounce capillaries at synchrotron beamlines

    NASA Astrophysics Data System (ADS)

    Huang, R.; Szebenyi, T.; Pfeifer, M.; Woll, A.; Smilgies, D.-M.; Finkelstein, K.; Dale, D.; Wang, Y.; Vila-Comamala, J.; Gillilan, R.; Cook, M.; Bilderback, D. H.

    2014-03-01

    Single-bounce capillaries are achromatic X-ray focusing optics that can provide efficient and high demagnification focusing with large numerical apertures. Capillary fabrication at CHESS can be customized according to specific application requirements. Exemplary applications are reviewed in this paper, as well as recent progress on condensers for high-resolution transmission X-ray microscopy and small focal size capillaries.

  6. PREFACE: 17th Pan-American Synchrotron Radiation Instrumentation Conference SRI2013

    NASA Astrophysics Data System (ADS)

    Williams, Gwyn P.; Revesz, Peter; Arp, Uwe

    2014-03-01

    These proceedings are a collection of the articles presented at the seventeenth Pan-American Synchrotron Radiation Instrumentation Conference SRI2013, held on the campus of the National Institute of Standards and Technology (NIST), located in Gaithersburg, Maryland, United States of America, 19-21 June, 2013. SRI2013 was jointly hosted by the Cornell University Cornell High Energy Synchrotron Source (CHESS), the Thomas Jefferson National Accelerator Facility (Jefferson Lab), and the Synchrotron Ultraviolet Radiation Facility (SURF III) at NIST. This meeting's focus was clearly on instrumentation, thus fulfilling the intent of this SRI meeting series, which was initiated at NIST, then the National Bureau of Standards (NBS), in 1979. SRI2013 hosted more than 150 delegates, despite the new US governmental travel restrictions. This proceedings series aims to be an essential reference work for practitioners in the field. It primarily documents the evolution and development of techniques, but also recent scientific advances, that were presented during the two and a half days of the conference. We are extremely thankful to all the authors who contributed to making these proceedings a volume of reference as well as to the reviewers for their careful reading and constructive recommendations for improving the articles. Great thanks go to Robert Dragoset at NIST, for creating and maintaining the conference website and generating the conference logo. We are also thankful for the excellent support we received from the Conference Program at NIST, especially Kathy Kilmer and Angela Ellis. And we would like to dedicate these proceedings to the memory of Kathy Kilmer, who passed away on 15 October, 2013. NIST will not be the same without her. The Co-Editors: Uwe Arp (SURF/NIST) Peter Reversz (CHESS) Gwyn P Williams (Jefferson Lab)

  7. Beam position monitoring system at CESR

    NASA Astrophysics Data System (ADS)

    Billing, M. G.; Bergan, W. F.; Forster, M. J.; Meller, R. E.; Rendina, M. C.; Rider, N. T.; Sagan, D. C.; Shanks, J.; Sikora, J. P.; Stedinger, M. G.; Strohman, C. R.; Palmer, M. A.; Holtzapple, R. L.

    2017-09-01

    The Cornell Electron-positron Storage Ring (CESR) has been converted from a High Energy Physics electron-positron collider to operate as a dedicated synchrotron light source for the Cornell High Energy Synchrotron Source (CHESS) and to conduct accelerator physics research as a test accelerator, capable of studying topics relevant to future damping rings, colliders and light sources. Some of the specific topics that were targeted for the initial phase of operation of the storage ring in this mode, labeled CESRTA (CESR as a Test Accelerator), included 1) tuning techniques to produce low emittance beams, 2) the study of electron cloud development in a storage ring and 3) intra-beam scattering effects. The complete conversion of CESR to CESRTA occurred over a several year period and is described elsewhere. As a part of this conversion the CESR beam position monitoring (CBPM) system was completely upgraded to provide the needed instrumental capabilities for these studies. This paper describes the new CBPM system hardware, its function and representative measurements performed by the upgraded system.

  8. Experimental measurement of lattice strain pole figures using synchrotron x rays

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miller, M.P.; Bernier, J.V.; Park, J.-S.

    This article describes a system for mechanically loading test specimens in situ for the determination of lattice strain pole figures and their evolution in multiphase alloys via powder diffraction. The data from these experiments provide insight into the three-dimensional mechanical response of a polycrystalline aggregate and represent an extremely powerful material model validation tool. Relatively thin (0.5 mm) iron/copper specimens were axially strained using a mechanical loading frame beyond the macroscopic yield strength of the material. The loading was halted at multiple points during the deformation to conduct a diffraction experiment using a 0.5x0.5 mm{sup 2} monochromatic (50 keV) xmore » ray beam. Entire Debye rings of data were collected for multiple lattice planes ({l_brace}hkl{r_brace}'s) in both copper and iron using an online image plate detector. Strain pole figures were constructed by rotating the loading frame about the specimen transverse direction. Ideal powder patterns were superimposed on each image for the purpose of geometric correction. The chosen reference material was cerium (IV) oxide powder, which was spread in a thin layer on the downstream face of the specimen using petroleum jelly to prevent any mechanical coupling. Implementation of the system at the A2 experimental station at the Cornell High Energy Synchrotron Source (CHESS) is described. The diffraction moduli measured at CHESS were shown to compare favorably to in situ data from neutron-diffraction experiments conducted on the same alloys.« less

  9. Measurement techniques for low emittance tuning and beam dynamics at CESR

    NASA Astrophysics Data System (ADS)

    Billing, M. G.; Dobbins, J. A.; Forster, M. J.; Kreinick, D. L.; Meller, R. E.; Peterson, D. P.; Ramirez, G. A.; Rendina, M. C.; Rider, N. T.; Sagan, D. C.; Shanks, J.; Sikora, J. P.; Stedinger, M. G.; Strohman, C. R.; Williams, H. A.; Palmer, M. A.; Holtzapple, R. L.; Flanagan, J.

    2018-03-01

    After operating as a High Energy Physics electron-positron collider, the Cornell Electron-positron Storage Ring (CESR) has been converted to become a dedicated synchrotron light source for the Cornell High Energy Synchrotron Source (CHESS). Over the course of several years CESR was adapted for accelerator physics research as a test accelerator, capable of studying topics relevant to future damping rings, colliders and light sources. Initially some specific topics were targeted for accelerator physic research with the storage ring in this mode, labeled CesrTA. These topics included 1) tuning techniques to produce low emittance beams, 2) the study of electron cloud (EC) development in a storage ring and 3) intra-beam scattering effects. The complete conversion of CESR to CesrTA occurred over a several year period, described elsewhere [1–3]. A number of specific instruments were developed for CesrTA. Much of the pre-existing instrumentation was modified to accommodate the scope of these studies and these are described in a companion paper [4]. To complete this research, a number of procedures were developed or modified, often requiring coordinated measurements among different instruments [5]. This paper provides an overview of types of measurements employed for the study of beam dynamics during the operation of CesrTA.

  10. 77 FR 58871 - Proposal Review Panel for Materials Research; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-24

    ... Source (CHESS) at Cornell University by the Division of Materials Research (DMR) 1203 Dates & Times... and further support of the CHESS facility at Cornell. Agenda Sunday, October 28, 2012 5:45 p.m.-7 p.m. Closed--Executive Session 7 p.m.-8:30 p.m. Open--Tour of CHESS Monday, October 29, 2012 8 a.m.-4 p.m...

  11. There Is Time for Calculation in Speed Chess, and Calculation Accuracy Increases With Expertise.

    PubMed

    Chang, Yu-Hsuan A; Lane, David M

    2016-01-01

    The recognition-action theory of chess skill holds that expertise in chess is due primarily to the ability to recognize familiar patterns of pieces. Despite its widespread acclaim, empirical evidence for this theory is indirect. One source of indirect evidence is that there is a high correlation between speed chess and standard chess. Assuming that there is little or no time for calculation in speed chess, this high correlation implies that calculation is not the primary factor in standard chess. Two studies were conducted analyzing 100 games of speed chess. In Study 1, we examined the distributions of move times, and the key finding was that players often spent considerable time on a few moves. Moreover, stronger players were more likely than weaker players to do so. Study 2 examined skill differences in calculation by examining poor moves. The stronger players made proportionally fewer blunders (moves that a 2-ply search would have revealed to be errors). Overall, the poor moves made by the weaker players would have required a less extensive search to be revealed as poor moves than the poor moves made by the stronger players. Apparently, the stronger players are searching deeper and more accurately. These results are difficult to reconcile with the view that speed chess does not allow players time to calculate extensively and call into question the assertion that the high correlation between speed chess and standard chess supports recognition-action theory.

  12. 78 FR 19535 - Proposal Review Panel for Materials Research; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-01

    ... Source (CHESS) at Cornell University by the Division of Materials Research (DMR) 1203 Dates & Times... and further support of the CHESS facility at Cornell. Agenda: Sunday, April 28, 2013 5:45 p.m.-7:15 p...:00 a.m.-3:00 p.m. Open--Review of CHESS 3:00 p.m.-4:40 p.m. Closed--Executive session 4:40 p.m.-8:00...

  13. Lithographically-fabricated channel arrays for confocal x-ray fluorescence microscopy and XAFS

    NASA Astrophysics Data System (ADS)

    Woll, Arthur R.; Agyeman-Budu, David; Choudhury, Sanjukta; Coulthard, Ian; Finnefrock, Adam C.; Gordon, Robert; Hallin, Emil; Mass, Jennifer

    2014-03-01

    Confocal X-ray Fluorescence Microscopy (CXRF) employs overlapping focal regions of two x-ray optics—a condenser and collector—to directly probe a 3D volume. The minimum-achievable size of this probe volume is limited by the collector, for which polycapillaries are generally the optic of choice. Recently, we demonstrated an alternative collection optic for CXRF, consisting of an array of micron-scale collimating channels, etched in silicon, and arranged like spokes of a wheel directed towards a single source position. The optic, while successful, had a working distance of only 0.2 mm and exhibited relatively low total collection efficiency, limiting its practical application. Here, we describe a new design in which the collimating channels are formed by a staggered array of pillars whose side-walls taper away from the channel axis. This approach improves both collection efficiency and working distance, while maintaining excellent spatial resolution. We illustrate these improvements with confocal XRF data obtained at the Cornell High Energy Synchrotron Source (CHESS) and the Advanced Photon Source (APS) beamline 20-ID-B.

  14. Instrumentation for the study of low emittance tuning and beam dynamics at CESR

    NASA Astrophysics Data System (ADS)

    Billing, M. G.; Dobbins, J. A.; Forster, M. J.; Kreinick, D. L.; Meller, R. E.; Peterson, D. P.; Ramirez, G. A.; Rendina, M. C.; Rider, N. T.; Sagan, D. C.; Shanks, J.; Sikora, J. P.; Stedinger, M. G.; Strohman, C. R.; Williams, H. A.; Palmer, M. A.; Holtzapple, R. L.; Flanagan, J.

    2017-11-01

    The Cornell Electron-positron Storage Ring (CESR) has been converted from a High Energy Physics electron-positron collider to operate as a dedicated synchrotron light source for the Cornell High Energy Synchrotron Source (CHESS) and to conduct accelerator physics research as a test accelerator, capable of studying topics relevant to future damping rings, colliders and light sources. Some of the specific topics that were targeted for the initial phase of operation of the storage ring in this mode for CESR as a Test Accelerator (CesrTA) included 1) tuning techniques to produce low emittance beams, 2) the study of electron cloud development in a storage ring and 3) intra-beam scattering effects. The complete conversion of CESR to CesrTA occurred over a several year period, described elsewhere [1-3]. In addition to instrumentation for the storage ring, which was created for CesrTA, existing instrumentation was modified to facilitate the entire range of investigations to support these studies. Procedures were developed, often requiring coordinated measurements among different instruments [4]. This paper describes the instruments utilized for the study of beam dynamics during the operation of CesrTA. The treatment of these instruments will remain fairly general in this paper as it focusses on an overview of the instruments themselves. Their interaction and inter-relationships during sequences of observations is found in a companion paper describing the associated measurement techniques. More detailed descriptions and detailed operational performance for some of the instrumentation may be found elsewhere and these will be referenced in the related sections of this paper.

  15. The protostar OMC-2 FIR 4: Results from the CHESS Herschel/HIFI spectral survey

    NASA Astrophysics Data System (ADS)

    Kama, Mihkel; Lopez-Sepulcre, Ana; Ceccarelli, Cecilia; Dominik, Carsten; Caux, Emmanuel; Fuente, Asuncion

    2013-07-01

    The intermediate-mass protostar OMC-2 FIR 4 in Orion is the focus of several ongoing studies, including a CHESS key programme Herschel/HIFI spectral survey. In this poster, we review recent CHESS results on this source, including the properties of the central hot core, the presence of a compact outflow, the spatial variation of the chemical composition, and the discovery of a tenuous foreground cloud. The HIFI spectrum of FIR 4 contains 719 lines from 40 species and isotopologs. Cooling by lines detectable with our sensitivity contributes 2% of the total in the 480 to 1900 GHz range. The total line flux is dominated by CO, followed by H2O and CH3OH. Initial comparisons with spectral surveys of other sources will also be presented.

  16. QEEG-based neural correlates of decision making in a well-trained eight year-old chess player.

    PubMed

    Alipour, Abolfazl; Seifzadeh, Sahar; Aligholi, Hadi; Nami, Mohammad

    2017-10-25

    The neurocognitive substrates of decision making (DM) in the context of chess has appealed to researchers' interest for decades. Expert and beginner chess players are hypothesized to employ different brain functional networks when involved in episodes of critical DM upon chess. Cognitive capacities including, but not restricted to pattern recognition, visuospatial search, reasoning, planning and DM are perhaps the key determinants of rewarding and judgmental decisions in chess. Meanwhile, the precise neural correlates of DM in this context has largely remained elusive. The quantitative electroencephalography (QEEG) is an investigation tool possessing a proper temporal resolution in the study of neural correlates of cognitive tasks at cortical level. Here, we used a 22-channel EEG setup and digital polygraphy in a well-trained 8 year-old boy while engaged in playing chess against the computer. Quantitative analyses were done to map and source-localize the EEG signals. Our analyses indicated a lower power spectral density (PSD) for higher frequency bands in the right hemisphere upon DM-related epochs. Moreover, the information flow upon DM blocks in this particular case was more of posterior towards anterior brain regions.

  17. Construction of CHESS compact undulator magnets at Kyma

    NASA Astrophysics Data System (ADS)

    Temnykh, Alexander B.; Lyndaker, Aaron; Kokole, Mirko; Milharcic, Tadej; Pockar, Jure; Geometrante, Raffaella

    2015-05-01

    In 2014 KYMA S.r.l. has built two CHESS Compact Undulator (CCU) magnets that are at present installed and successfully operate at the Cornell Electron Storage Ring. This type of undulator was developed for upgrade of Cornell High Energy Synchrotron Source beam-lines, but it can be used elsewhere as well. CCU magnets are compact, lightweight, cost efficient and in-vacuum compatible. They are linearly polarized undulators and have a fixed gap. Magnetic field tuning is achieved by phasing (shifting) top magnetic array relative bottom. Two CCUs constructed by KYMA S.r.l. have 28.4 mm period, 6.5 mm gap, 0.93 T peak field. Magnetic structure is of PPM type, made with NdFeB (40UH grade) permanent magnet material. Transitioning from the laboratory to industrial environment for a novel design required additional evaluation, design adjusting and extensive testing. Particular attention was given to the soldering technique used for fastening of the magnetic blocks to holders. This technique had thus far never been used before for undulator magnet construction by industry. The evaluation included tests of different types of soldering paste, measurements of strength of solder and determining the deformations of the soldered magnet and holder under simulated loading forces. This paper focuses on critical features of the CCU design, results of the soldering technique testing and the data regarding permanent magnets magnetization change due to soldering. In addition it deals with optimization-assisted assembly and the performance of the assembled devices and assesses some of the results of the CCU magnets operation at CESR.

  18. CHESS upgrade 1995: Improved radiation shielding (abstract)

    NASA Astrophysics Data System (ADS)

    Finkelstein, K. D.

    1996-09-01

    The Cornell Electron Storage Ring (CESR) stores electrons and positrons at 5.3 GeV for the production and study of B mesons, and, in addition, it supplies synchrotron radiation for CHESS. The machine has been upgraded for 300 mA operation. It is planned that each beam will be injected in about 5 minutes and that particle beam lifetimes will be several hours. In a cooperative effort, staff members at CHESS and LNS have studied sources in CESR that produce radiation in the user areas. The group has been responsible for the development and realization of new tunnel shielding walls that provide a level of radiation protection from 20 to ≳100 times what was previously available. Our experience has indicated that a major contribution to the environmental radiation is not from photons, but results from neutrons that are generated by particle beam loss in the ring. Neutrons are stopped by inelastic scattering and absorption in thick materials such as heavy concrete. The design for the upgraded walls, the development of a mix for our heavy concrete, and all the concrete casting was done by CHESS and LNS personnel. The concrete incorporates a new material for this application, one that has yielded a significant cost saving in the production of over 200 tons of new wall sections. The material is an artificially enriched iron oxide pellet manufactured in vast quantities from hematite ore for the steel-making industry. Its material and chemical properties (iron and impurity content, strength, size and uniformity) make it an excellent substitute for high grade Brazilian ore, which is commonly used as heavy aggregate in radiation shielding. Its cost is about a third that of the natural ore. The concrete has excellent workability, a 28 day compressive strength exceeding 6000 psi and a density of 220 lbs/cu.ft (3.5 gr/cc). The density is limited by an interesting property of the pellets that is motivated by efficiency in the steel-making application. The pellets are made to be porous, with about 28% of the volume consisting of connected pores of size typically from 1-10 microns. The porosity may have some useful implications for neutron radiation shielding including the possibility of holding a lot more water than a conventional mix, and the opportunity to impregnate the pellets with a good neutron absorber such as boron. This paper will discuss these developments and report the latest results on the effectiveness of the upgraded shielding at Cornell.

  19. Expression, crystallization and preliminary X-ray diffraction studies of recombinant Clostridium perfringens β2-toxin

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gurjar, Abhijit A.; Yennawar, Neela H.; Yennawar, Hemant P.

    2007-06-01

    The cloning, expression, purification and crystallization of recombinant Clostridium perfringens β2-toxin is described. The crystals diffracted to 2.9 Å resolution. Clostridium perfringens is a Gram-positive sporulating anaerobic bacterium that is responsible for a wide spectrum of diseases in animals, birds and humans. The virulence of C. perfringens is associated with the production of several enterotoxins and exotoxins. β2-toxin is a 28 kDa exotoxin produced by C. perfringens. It is implicated in necrotic enteritis in animals and humans, a disease characterized by a sudden acute onset with lethal hemorrhagic mucosal ulceration. The recombinant expression, purification and crystallization of β2-toxin using themore » batch-under-oil technique are reported here. Native X-ray diffraction data were obtained to 2.9 Å resolution on a synchrotron beamline at the F2 station at Cornell High Energy Synchrotron Source (CHESS) using an ADSC Quantum-210 CCD detector. The crystals belong to space group R3, with a dimer in the asymmetric unit; the unit-cell parameters are a = b = 103.71, c = 193.48 Å, α = β = 90, γ = 120° using the hexagonal axis setting. A self-rotation function shows that the two molecules are related by a noncrystallographic twofold axis with polar angles ω = 90.0, ϕ = 210.3°.« less

  20. Recall of briefly presented chess positions and its relation to chess skill.

    PubMed

    Gong, Yanfei; Ericsson, K Anders; Moxley, Jerad H

    2015-01-01

    Individual differences in memory performance in a domain of expertise have traditionally been accounted for by previously acquired chunks of knowledge and patterns. These accounts have been examined experimentally mainly in chess. The role of chunks (clusters of chess pieces recalled in rapid succession during recall of chess positions) and their relations to chess skill are, however, under debate. By introducing an independent chunk-identification technique, namely repeated-recall technique, this study identified individual chunks for particular chess players. The study not only tested chess players with increasing chess expertise, but also tested non-chess players who should not have previously acquired any chess related chunks in memory. For recall of game positions significant differences between players and non-players were found in virtually all the characteristics of chunks recalled. Size of the largest chunks also correlates with chess skill within the group of rated chess players. Further research will help us understand how these memory encodings can explain large differences in chess skill.

  1. Recall of Briefly Presented Chess Positions and Its Relation to Chess Skill

    PubMed Central

    Moxley, Jerad H.

    2015-01-01

    Individual differences in memory performance in a domain of expertise have traditionally been accounted for by previously acquired chunks of knowledge and patterns. These accounts have been examined experimentally mainly in chess. The role of chunks (clusters of chess pieces recalled in rapid succession during recall of chess positions) and their relations to chess skill are, however, under debate. By introducing an independent chunk-identification technique, namely repeated-recall technique, this study identified individual chunks for particular chess players. The study not only tested chess players with increasing chess expertise, but also tested non-chess players who should not have previously acquired any chess related chunks in memory. For recall of game positions significant differences between players and non-players were found in virtually all the characteristics of chunks recalled. Size of the largest chunks also correlates with chess skill within the group of rated chess players. Further research will help us understand how these memory encodings can explain large differences in chess skill. PMID:25774693

  2. Systematic and Performance Tests of the Hard X-ray Polarimeter X-Calibur

    NASA Astrophysics Data System (ADS)

    Endsley, Ryan; Beilicke, Matthias; Kislat, Fabian; Krawczynski, Henric; X-Calibur/InFOCuS

    2015-01-01

    X-ray polarimetry has great potential to reveal new astrophysical information about the emission processes of high energy sources such as black hole environments, X-ray binary systems, and active galactic nuclei. Here we present the results and conclusions of systematic and performance measurements of the hard X-ray polarimeter, X-Calibur. Designed to be flown on a balloon-borne X-ray telescope, X-Calibur will achieve unprecedented sensitivity and makes use of the fact that polarized X-rays preferentially Compton-scatter perpendicular to their E-field vector. Extensive laboratory measurements taken at Washington University and the Cornell High-Energy Synchrotron Source (CHESS) indicate that X-Calibur combines a detection efficiency on the order of unity with a high modulation factor of µ ≈ 0.5 averaged over the whole detector assembly, and with values up to µ ≈ 0.7 for select subsections of the polarimeter. Additionally, we are able to suppress background flux by more than two orders of magnitude by utilizing an active shield and scintillator coincidence. Comparing laboratory data with Monte Carlo simulations of both polarized and unpolarized hard X-ray beams illustrate that we have an exceptional understanding of the detector response.

  3. Chess knowledge predicts chess memory even after controlling for chess experience: Evidence for the role of high-level processes.

    PubMed

    Lane, David M; Chang, Yu-Hsuan A

    2018-04-01

    The expertise effect in memory for chess positions is one of the most robust effects in cognitive psychology. One explanation of this effect is that chess recall is based on the recognition of familiar patterns and that experts have learned more and larger patterns. Template theory and its instantiation as a computational model are based on this explanation. An alternative explanation is that the expertise effect is due, in part, to stronger players having better and more conceptual knowledge, with this knowledge facilitating memory performance. Our literature review supports the latter view. In our experiment, a sample of 79 chess players were given a test of memory for chess positions, a test of declarative chess knowledge, a test of fluid intelligence, and a questionnaire concerning the amount of time they had played nontournament chess and the amount of time they had studied chess. We determined the numbers of tournament games the players had played from chess databases. Chess knowledge correlated .67 with chess memory and accounted for 16% of the variance after controlling for chess experience. Fluid intelligence accounted for an additional 13% of the variance. These results support the conclusion that both high-level conceptual processing and low-level recognition of familiar patterns play important roles in memory for chess positions.

  4. Personality of Elite Male and Female Chess Players and Its Relation to Chess Skill

    ERIC Educational Resources Information Center

    Vollstadt-Klein, Sabine; Grimm, Oliver; Kirsch, Peter; Bilalic, Merim

    2010-01-01

    Whereas a lot of studies examine cognitive processes in chess players, personality profiles of elite chess players are still not described well. The aim of this study was to examine personality of strong chess experts and its influence on chess skill. We tested elite male and female chess players with Freiburg Personality Inventory Revised…

  5. Chess in Schools: Evaluation Report and Executive Summary

    ERIC Educational Resources Information Center

    Jerrim, John; Macmillan, Lindsey; Micklewright, John; Sawtell, Mary; Wiggins, Meg

    2016-01-01

    Chess in Primary Schools is a whole-school approach to teaching primary school children how to play chess. Children take 30 hours of chess lessons delivered by a tutor who is an experienced chess player, and the school is given the option to set up a chess club as a lunchtime or after-school activity. Chess classes are delivered during the school…

  6. Planning abilities and chess: a comparison of chess and non-chess players on the Tower of London task.

    PubMed

    Unterrainer, J M; Kaller, C P; Halsband, U; Rahm, B

    2006-08-01

    Playing chess requires problem-solving capacities in order to search through the chess problem space in an effective manner. Chess should thus require planning abilities for calculating many moves ahead. Therefore, we asked whether chess players are better problem solvers than non-chess players in a complex planning task. We compared planning performance between chess ( N=25) and non-chess players ( N=25) using a standard psychometric planning task, the Tower of London (ToL) test. We also assessed fluid intelligence (Raven Test), as well as verbal and visuospatial working memory. As expected, chess players showed better planning performance than non-chess players, an effect most strongly expressed in difficult problems. On the other hand, they showed longer planning and movement execution times, especially for incorrectly solved trials. No differences in fluid intelligence and verbal/visuospatial working memory were found between both groups. These findings indicate that better performance in chess players is associated with disproportionally longer solution times, although it remains to be investigated whether motivational or strategic differences account for this result.

  7. Analysis of Methods to Excite Head-Tail Motion Within the Cornell Electron Storage Ring

    NASA Astrophysics Data System (ADS)

    Gendler, Naomi; Billing, Mike; Shanks, Jim

    The main accelerator complex at Cornell consists of two rings around which electrons and positrons move: the synchrotron, where the particles are accelerated to 5 GeV, and the Storage Ring, where the particles circulate a ta Þxed energy, guided by quadrupole and dipole magnets, with a steady energy due to a sinusoidal voltage source. Keeping the beam stable in the Storage Ring is crucial for its lifetime. A long-lasting, invariable beam means more accurate experiments, as well as brighter, more focused X-rays for use in the Cornell High Energy Synchrotron Source (CHESS). The stability of the electron and positron beams in the Cornell Electron Storage Ring (CESR) is important for the development of accelerators and for usage of the beam in X-ray science and accelerator physics. Bunch oscillations tend to enlarge the beam's cross section, making it less stable. We believe that one such oscillation is ``head-tail motion,'' where the bunch rocks back and forth on a pivot located at the central particle. In this project, we write a simulation of the bunch that induces head-tail motion with a vertical driver. We also excite this motion physically in the storage ring, and observe a deÞnite head-tail signal. In the experiment, we saw a deÞnite persistence of the drive-damp signal within a small band around the head-tail frequency, indicating that the head-tail frequency is a natural vertical mode of the bunch that was being excited. The signal seen in the experiment matched the signal seen in the simulation to within an order of magnitude.

  8. Deliberate practice predicts performance over time in adolescent chess players and drop-outs: a linear mixed models analysis.

    PubMed

    de Bruin, Anique B H; Smits, Niels; Rikers, Remy M J P; Schmidt, Henk G

    2008-11-01

    In this study, the longitudinal relation between deliberate practice and performance in chess was examined using a linear mixed models analysis. The practice activities and performance ratings of young elite chess players, who were either in, or had dropped out of the Dutch national chess training, were analysed since they had started playing chess seriously. The results revealed that deliberate practice (i.e. serious chess study alone and serious chess play) strongly contributed to chess performance. The influence of deliberate practice was not only observable in current performance, but also over chess players' careers. Moreover, although the drop-outs' chess ratings developed more slowly over time, both the persistent and drop-out chess players benefited to the same extent from investments in deliberate practice. Finally, the effect of gender on chess performance proved to be much smaller than the effect of deliberate practice. This study provides longitudinal support for the monotonic benefits assumption of deliberate practice, by showing that over chess players' careers, deliberate practice has a significant effect on performance, and to the same extent for chess players of different ultimate performance levels. The results of this study are not in line with critique raised against the deliberate practice theory that the factors deliberate practice and talent could be confounded.

  9. Auditory memory function in expert chess players.

    PubMed

    Fattahi, Fariba; Geshani, Ahmad; Jafari, Zahra; Jalaie, Shohreh; Salman Mahini, Mona

    2015-01-01

    Chess is a game that involves many aspects of high level cognition such as memory, attention, focus and problem solving. Long term practice of chess can improve cognition performances and behavioral skills. Auditory memory, as a kind of memory, can be influenced by strengthening processes following long term chess playing like other behavioral skills because of common processing pathways in the brain. The purpose of this study was to evaluate the auditory memory function of expert chess players using the Persian version of dichotic auditory-verbal memory test. The Persian version of dichotic auditory-verbal memory test was performed for 30 expert chess players aged 20-35 years and 30 non chess players who were matched by different conditions; the participants in both groups were randomly selected. The performance of the two groups was compared by independent samples t-test using SPSS version 21. The mean score of dichotic auditory-verbal memory test between the two groups, expert chess players and non-chess players, revealed a significant difference (p≤ 0.001). The difference between the ears scores for expert chess players (p= 0.023) and non-chess players (p= 0.013) was significant. Gender had no effect on the test results. Auditory memory function in expert chess players was significantly better compared to non-chess players. It seems that increased auditory memory function is related to strengthening cognitive performances due to playing chess for a long time.

  10. The Fourth Flight of CHESS: Analysis of Interstellar H2 on the γ Ara Sightline

    NASA Astrophysics Data System (ADS)

    Kruczek, Nick E.; France, Kevin; Nell, Nicholas; Fleming, Brian

    2018-06-01

    In this talk, we describe the scientific motivation and technical development of the Colorado High-resolution Echelle Stellar Spectrograph (CHESS) sounding rocket, focusing on the preliminary science results for the fourth launch of the payload (CHESS-4). CHESS is a far ultraviolet rocket-borne instrument designed to study the atomic-to-molecular transitions within translucent cloud regions in the interstellar medium. CHESS-4 launched on 13 April 2018 aboard NASA/CU sounding rocket mission 36.333 UG. The target for this flight was γ Ara, a B1I star that is known to display a variable and equatorially enhanced stellar wind. We present flight results of interstellar molecular hydrogen excitation, including initial measurements of the column density and temperature, on the sightline. These results are compared to previous values that were calculated using the damping wings of low-J H2 absorption features in Copernicus spectra. We also present analogous flight data for the sightline toward β Sco, finding that the derived column density of the J” = 1 rotational level differs by a factor of ~2 when compared to the previous observations. We discuss the discrepancies between the two measurements and show that the source of the difference is likely due to the opacity of higher rotational levels contributing to the J” = 1 absorption wing, increasing the inferred column density in the previous work.

  11. Is Chess Just a Game, or Is It a Mirror That Reflects the Child's Inner World?

    ERIC Educational Resources Information Center

    Gunes, Gokhan; Tugrul, Belma

    2017-01-01

    Children learn so many things (rules, science, mathematics, etc.) by the help of the games. Chess is also an enjoyable game for most children. The chess grandmaster Karpov stated that chess is everything--art, science, and sport. However, this raises the questions concerning how children evaluate chess and whether chess reflects the child's inner…

  12. Auditory memory function in expert chess players

    PubMed Central

    Fattahi, Fariba; Geshani, Ahmad; Jafari, Zahra; Jalaie, Shohreh; Salman Mahini, Mona

    2015-01-01

    Background: Chess is a game that involves many aspects of high level cognition such as memory, attention, focus and problem solving. Long term practice of chess can improve cognition performances and behavioral skills. Auditory memory, as a kind of memory, can be influenced by strengthening processes following long term chess playing like other behavioral skills because of common processing pathways in the brain. The purpose of this study was to evaluate the auditory memory function of expert chess players using the Persian version of dichotic auditory-verbal memory test. Methods: The Persian version of dichotic auditory-verbal memory test was performed for 30 expert chess players aged 20-35 years and 30 non chess players who were matched by different conditions; the participants in both groups were randomly selected. The performance of the two groups was compared by independent samples t-test using SPSS version 21. Results: The mean score of dichotic auditory-verbal memory test between the two groups, expert chess players and non-chess players, revealed a significant difference (p≤ 0.001). The difference between the ears scores for expert chess players (p= 0.023) and non-chess players (p= 0.013) was significant. Gender had no effect on the test results. Conclusion: Auditory memory function in expert chess players was significantly better compared to non-chess players. It seems that increased auditory memory function is related to strengthening cognitive performances due to playing chess for a long time. PMID:26793666

  13. Relative Age Effect in Mind Games: The Evidence from Elite Chess.

    PubMed

    Breznik, Kristijan; Law, Kris M Y

    2016-04-01

    Numerous studies have attempted to investigate the factors affecting superior intellectual performance, and it has been proposed that a possible biological marker for superior intellectual performance is the month of birth. In this study, birth details of chess players were obtained from the official international chess federation website. The rating lists of top junior female chess players ("Girls" category), top junior male chess players ("Boys"), top female chess players ("Female"), and top male chess players ("Male") were collected between July 2000 and August 2015. The birth months of each player that appeared in the top rating list were categorized into quarters. Additionally, relative age of chess players was calculated. Results supported the existence of the relative age effect in chess in all categories although a "reverse" RAE was found in the "Male" category. © The Author(s) 2016.

  14. On the Interfaces among Educational Technology, Creativity, and Chess

    ERIC Educational Resources Information Center

    Bart, William

    2016-01-01

    This article provides an examination of interrelationships among educational technology, creativity, and chess. It presents the argument that chess training fosters significant gains in scholastic achievement and cognitive ability. As a vital component in chess training programs, contemporary chess software such as Fritz serves as impressive…

  15. Talent Developed: Conversations with Masters of the Arts and Sciences.

    ERIC Educational Resources Information Center

    Subotnik, Rena F.

    1993-01-01

    This interview with Sunil Weeramantry, a World Chess Federation Master, examines his initial involvement in the world of chess, changes in the field of chess, the role of mentors, the qualifications and role of the chess coach, and the development of chess talent in young children. (DB)

  16. The neural organization of perception in chess experts.

    PubMed

    Krawczyk, Daniel C; Boggan, Amy L; McClelland, M Michelle; Bartlett, James C

    2011-07-20

    The human visual system responds to expertise, and it has been suggested that regions that process faces also process other objects of expertise including chess boards by experts. We tested whether chess and face processing overlap in brain activity using fMRI. Chess experts and novices exhibited face selective areas, but these regions showed no selectivity to chess configurations relative to other stimuli. We next compared neural responses to chess and to scrambled chess displays to isolate areas relevant to expertise. Areas within the posterior cingulate, orbitofrontal cortex, and right temporal cortex were active in this comparison in experts over novices. We also compared chess and face responses within the posterior cingulate and found this area responsive to chess only in experts. These findings indicate that the configurations in chess are not strongly processed by face-selective regions that are selective for faces in individuals who have expertise in both domains. Further, the area most consistently involved in chess did not show overlap with faces. Overall, these results suggest that expert visual processing may be similar at the level of recognition, but need not show the same neural correlates. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  17. Chess players' eye movements reveal rapid recognition of complex visual patterns: Evidence from a chess-related visual search task.

    PubMed

    Sheridan, Heather; Reingold, Eyal M

    2017-03-01

    To explore the perceptual component of chess expertise, we monitored the eye movements of expert and novice chess players during a chess-related visual search task that tested anecdotal reports that a key differentiator of chess skill is the ability to visualize the complex moves of the knight piece. Specifically, chess players viewed an array of four minimized chessboards, and they rapidly searched for the target board that allowed a knight piece to reach a target square in three moves. On each trial, there was only one target board (i.e., the "Yes" board), and for the remaining "lure" boards, the knight's path was blocked on either the first move (the "Easy No" board) or the second move (i.e., "the Difficult No" board). As evidence that chess experts can rapidly differentiate complex chess-related visual patterns, the experts (but not the novices) showed longer first-fixation durations on the "Yes" board relative to the "Difficult No" board. Moreover, as hypothesized, the task strongly differentiated chess skill: Reaction times were more than four times faster for the experts relative to novices, and reaction times were correlated with within-group measures of expertise (i.e., official chess ratings, number of hours of practice). These results indicate that a key component of chess expertise is the ability to rapidly recognize complex visual patterns.

  18. Experience, Spatial Abilities, and Chess Skill.

    ERIC Educational Resources Information Center

    Horgan, Dianne D.; Morgan, David

    A study examined chess expertise in 113 children in grades 1-12 who played competitive chess. Specific attention was given to the relationship between experience, as measured by number of games played, and skill, as measured by national chess ratings. For the top 15 players, emphasis was placed on relationships among chess skill, spatial…

  19. Chess from Square a1: Incorporating Chess into the Gifted Class

    ERIC Educational Resources Information Center

    Adams, Thomasina C. P.

    2012-01-01

    Teachers of gifted students often are challenged to find ways to stimulate critical thinking and problem-solving skills. School chess clubs are one way of meeting that challenge. This article poses how games such as chess affect learning and gifted students. Two detailed strategies for teaching chess to students beginning in kindergarten are…

  20. Chess Expertise and Memory for Chess Positions in Children and Adults.

    ERIC Educational Resources Information Center

    Schneider, Wolfgang; And Others

    1993-01-01

    A study presented four groups of chess players (child experts and novices, adult experts and novices) with short-term memory tasks involving meaningful and random chess positions, as well as a control board composed of geometric-shaped spaces and pieces. Found that child experts' immediate recall for meaningful chess positions was far superior to…

  1. Playing chess unconsciously.

    PubMed

    Kiesel, Andrea; Kunde, Wilfried; Pohl, Carsten; Berner, Michael P; Hoffmann, Joachim

    2009-01-01

    Expertise in a certain stimulus domain enhances perceptual capabilities. In the present article, the authors investigate whether expertise improves perceptual processing to an extent that allows complex visual stimuli to bias behavior unconsciously. Expert chess players judged whether a target chess configuration entailed a checking configuration. These displays were preceded by masked prime configurations that either represented a checking or a nonchecking configuration. Chess experts, but not novice chess players, revealed a subliminal response priming effect, that is, faster responding when prime and target displays were congruent (both checking or both nonchecking) rather than incongruent. Priming generalized to displays that were not used as targets, ruling out simple repetition priming effects. Thus, chess experts were able to judge unconsciously presented chess configurations as checking or nonchecking. A 2nd experiment demonstrated that experts' priming does not occur for simpler but uncommon chess configurations. The authors conclude that long-term practice prompts the acquisition of visual memories of chess configurations with integrated form-location conjunctions. These perceptual chunks enable complex visual processing outside of conscious awareness.

  2. Many faces of expertise: fusiform face area in chess experts and novices.

    PubMed

    Bilalić, Merim; Langner, Robert; Ulrich, Rolf; Grodd, Wolfgang

    2011-07-13

    The fusiform face area (FFA) is involved in face perception to such an extent that some claim it is a brain module for faces exclusively. The other possibility is that FFA is modulated by experience in individuation in any visual domain, not only faces. Here we test this latter FFA expertise hypothesis using the game of chess as a domain of investigation. We exploited the characteristic of chess, which features multiple objects forming meaningful spatial relations. In three experiments, we show that FFA activity is related to stimulus properties and not to chess skill directly. In all chess and non-chess tasks, experts' FFA was more activated than that of novices' only when they dealt with naturalistic full-board chess positions. When common spatial relationships formed by chess objects in chess positions were randomly disturbed, FFA was again differentially active only in experts, regardless of the actual task. Our experiments show that FFA contributes to the holistic processing of domain-specific multipart stimuli in chess experts. This suggests that FFA may not only mediate human expertise in face recognition but, supporting the expertise hypothesis, may mediate the automatic holistic processing of any highly familiar multipart visual input.

  3. The architecture of the chess player's brain.

    PubMed

    Hänggi, Jürgen; Brütsch, Karin; Siegel, Adrian M; Jäncke, Lutz

    2014-09-01

    The game of chess can be seen as a typical example for an expertise task requiring domain-specific training and experience. Despite intensive behavioural studies the neural underpinnings of chess performance and expertise are not entirely understood. A few functional neuroimaging studies have shown that expert chess players recruit different psychological functions and activate different brain areas while they are engaged in chess-related activities. Based on this functional literature, we predicted to find morphological differences in a network comprised by parietal and frontal areas and especially the occipito-temporal junction (OTJ), fusiform gyrus, and caudate nucleus. Twenty expert chess players and 20 control subjects were investigated using voxel-based and surface-based morphometry as well as diffusion tensor imaging. Grey matter volume and cortical thickness were reduced in chess players compared with those of control men in the OTJ and precunei. The volumes of both caudate nuclei were not different between groups, but correlated inversely with the years of chess playing experience. Mean diffusivity was increased in chess players compared with that of controls in the left superior longitudinal fasciculus and the Elo score (a chess tournament ranking) was inversely related to mean diffusivity within the right superior longitudinal fasciculus. To the best of our knowledge we showed for the first time that there are specific differences in grey and white matter morphology between chess players and control subjects in brain regions associated with cognitive functions important for playing chess. Whether these anatomical alterations are the cause or consequence of the intensive and long-term chess training and practice remains to be shown in future studies. Copyright © 2014 Elsevier Ltd. All rights reserved.

  4. The third flight of the Colorado high-resolution echelle stellar spectrograph (CHESS): improvements, calibrations, and preliminary results

    NASA Astrophysics Data System (ADS)

    Kruczek, Nicholas; Nell, Nicholas; France, Kevin; Hoadley, Keri; Fleming, Brian; Kane, Robert; Ulrich, Stefan; Egan, Arika; Beatty, Dawson

    2017-08-01

    In this proceeding, we describe the scientific motivation and technical development of the Colorado HighResolution Echelle Stellar Spectrograph (CHESS), focusing on the hardware advancements and testing of components for the third launch of the payload (CHESS-3). CHESS is a far ultraviolet rocket-borne instrument designed to study the atomic-to-molecular transitions within translucent cloud regions in the interstellar medium. CHESS is an objective echelle spectrograph, which uses a mechanically-ruled echelle and a powered (f/12.4) crossdispersing grating, and is designed to achieve a resolving power R > 100,000 over the bandpass λλ 1000-1600 Å. Results from final efficiency and reflectivity measurements for the optical components of CHESS-3 are presented. An important role of sounding rocket experiments is the testing and verification of the space flight capabilities of experimental technologies. CHESS-3 utilizes a 40mm-diameter cross-strip anode microchannel plate detector fabricated by Sensor Sciences LLC, capable of achieving high spatial resolution and a high global count rate (˜1 MHz). We present pre-flight laboratory spectra and calibration results, including wavelength solution and resolving power of the instrument. The fourth launch of CHESS (CHESS-4) will demonstrate a δ-doped CCD, assembled in collaboration with the Microdevices Laboratory at JPL and Arizona State University. In support of CHESS-4, the CHESS-3 payload included a photomultiplier tube, used as a secondary confirmation of the optical alignment of the payload during flight. CHESS-3 launched on 26 June 2017 aboard NASA/CU sounding rocket mission 36.323 UG. We present initial flight results for the CHESS-3 observation of the β1 Scorpii sightline.

  5. Earth vs. Space Chess Match; Chamitoff Makes his Move

    NASA Image and Video Library

    2008-10-04

    NASA and the U.S. Chess Federation (USCF) are teaming up to host the first public chess match between astronaut Greg Chamitoff, in orbit aboard the International Space Station, and the public. Key players in the game, set to begin on Monday, Sept. 29, will be the kindergarten through third grade U.S. Chess Championship Team and its chess club teammates from Stevenson Elementary School in Bellevue, Wash.

  6. Checkmate: Capturing Gifted Students' Logical Thinking Using Chess.

    ERIC Educational Resources Information Center

    Rifner, Philip J.; Feldhusen, John F.

    1997-01-01

    Describes the use of chess instruction to develop abstract thinking skills and problem solving among gifted students. Offers suggestions for starting school chess programs, teaching and evaluating chess skills, and measuring the success of both student-players and the program in general. (PB)

  7. [Physical fitness in relation to age and body build of young chess players].

    PubMed

    Fornal-Urban, Agnieszka; Keska, Anna; Dobosz, Janusz; Nowacka-Dobosz, Sylwia

    2009-01-01

    Specificity of chess training promotes sedentary lifestyle and may reduce chess players participation in different physical activities. Limited physical activity leads to decrease of physical fitness and may augment the risk of overweight and obesity. It is suggested that these athletes will characterize more frequently lower physical fitness and weight/height proportions disorders. The aim of the study was evaluation of physical fitness and its relationship with age and body build of athletes. A sample of 73 individuals (35 girls--48% and 38 boys--52%) aged 8-19 years took part in this study. All competitors were members of national team and Polish representatives for the European and world chess championship. Chess players' physical fitness was measured by EUROFIT tests. With reference to the Polish population chess players characterized higher level of physical fitness. In six tests of EUROFIT chess players had better standardized results than controls. Sit ups (mean standardized result 0.842), shuttle run 10 x 5 m (0.577), standing broad jump (0.552) and flamingo balance (0.371) were very well performed by chess players. Only in one test, bent arm hang, sportsmen achieved worse results (-0.719). Permanent decrease of chess players' physical fitness with age was also observed. Although chess players' physical fitness was satisfied in comparison to age-matched control, it is recommended to include in their training more exercises developing strength. Because of changes in body build with age and decrease of physical fitness, chess players ought to participate in regular physical activity. Therefore chess organisers should provide the variety of active forms that can be chosen by competitors in their leisure time.

  8. [Acceptance and commitment therapy (ACT) and improving chess performance in promising young chess-players].

    PubMed

    Ruiz, Francisco J; Luciano, Carmen

    2009-08-01

    Acceptance and Commitment Therapy (ACT) is shown to be effective in relatively distant fields from the so-called psychological disorders. One of these areas is sport performance improvement. The aim of the current study is to expand the application of brief ACT protocols to improve chess-players' performance. In a previous study, a brief protocol was applied to international-level adult chess-players that was effective. The current study aims to apply an equivalent brief ACT protocol, but in this case, applied in a group format to promising young chess-players. In addition, this brief protocol is compared to a non-intervention control condition. Results show that the ACT brief protocol improved the performance in 5 out of 7 participants, and that none of the chess-players in the control condition reached the established change criterion. The differences between the conditions in chess performance were statistically significant. The results are discussed, emphasizing the replicated impact of a brief ACT protocol on the improvement of chess-players' performance.

  9. Frontal lobe function in chess players.

    PubMed

    Nejati, Majid; Nejati, Vahid

    2012-01-01

    Chess is considered as a cognitive game because of severe engagement of the mental resources during playing. The purpose of this study is evaluation of frontal lobe function of chess players with matched non-players. Wisconsin Card Sorting Test (WCST) data showed no difference between the player and non-player groups in preservation error and completed categories but surprisingly showed significantly lower grade of the player group in correct response. Our data reveal that chess players don't have any preference in any stage of Stroop test. Chess players don't have any preference in selective attention, inhibition and executive cognitive function. Chess players' have lower shifting abilities than non-players.

  10. Individual differences in chess expertise: a psychometric investigation.

    PubMed

    Grabner, Roland H; Stern, Elsbeth; Neubauer, Aljoscha C

    2007-03-01

    Starting from controversies over the role of general individual characteristics (especially intelligence) for the attainment of expert performance levels, a comprehensive psychometric investigation of individual differences in chess expertise is presented. A sample of 90 adult tournament chess players of varying playing strengths (1311-2387 ELO) was screened with tests on intelligence and personality variables; in addition, experience in chess play, tournament participation, and practice activities were assessed. Correlation and regression analyses revealed a clear-cut moderate relationship between general (and in particular numerical) intelligence and the participants' playing strengths, suggesting that expert chess play does not stand in isolation from superior mental abilities. The strongest predictor of the attained expertise level, however, was the participants' chess experience which highlights the relevance of long-term engagement for the development of expertise. Among all analysed personality dimensions, only domain-specific performance motivation and emotion expression control incrementally contributed to the prediction of playing strength. In total, measures of chess experience, current tournament activity, intelligence, and personality accounted for about 55% of variance in chess expertise. The present results suggest that individual differences in chess expertise are multifaceted and cannot be reduced to differences in domain experience.

  11. Upgrade of MacCHESS facility for X-ray scattering of biological macromolecules in solution

    PubMed Central

    Acerbo, Alvin Samuel; Cook, Michael J.; Gillilan, Richard Edward

    2015-01-01

    X-ray scattering of biological macromolecules in solution is an increasingly popular tool for structural biology and benefits greatly from modern high-brightness synchrotron sources. The upgraded MacCHESS BioSAXS station is now located at the 49-pole wiggler beamline G1. The 20-fold improved flux over the previous beamline F2 provides higher sample throughput and autonomous X-ray scattering data collection using a unique SAXS/WAXS dual detectors configuration. This setup achieves a combined q-range from 0.007 to 0.7 Å−1, enabling better characterization of smaller molecules, while opening opportunities for emerging wide-angle scattering methods. In addition, a facility upgrade of the positron storage ring to continuous top-up mode has improved beam stability and eliminated beam drift over the course of typical BioSAXS experiments. Single exposure times have been reduced to 2 s for 3.560 mg ml−1 lysozyme with an average quality factor I/σ of 20 in the Guinier region. A novel disposable plastic sample cell design that incorporates lower background X-ray window material provides users with a more pristine sample environment than previously available. Systematic comparisons of common X-ray window materials bonded to the cell have also been extended to the wide-angle regime, offering new insight into best choices for various q-space ranges. In addition, a quantitative assessment of signal-to-noise levels has been performed on the station to allow users to estimate necessary exposure times for obtaining usable signals in the Guinier regime. Users also have access to a new BioSAXS sample preparation laboratory which houses essential wet-chemistry equipment and biophysical instrumentation. User experiments at the upgraded BioSAXS station have been on-going since commissioning of the beamline in Summer 2013. A planned upgrade of the G1 insertion device to an undulator for the Winter 2014 cycle is expected to further improve flux by an order of magnitude. PMID:25537607

  12. Children and Chess: A Guide for Educators

    ERIC Educational Resources Information Center

    Root, Alexey

    2006-01-01

    "Children and Chess: A Guide for Educators" is the first book to show the connection between accepted educational theories and chess. The relationship of chess to academic and humanistic educational goals is convincingly illustrated as curriculum and psychological theories from John D. McNeil, Mihaly Csikszentmihalyi, and Howard Gardner are…

  13. Why Chess in the Schools.

    ERIC Educational Resources Information Center

    Hall, Ralph L.

    The game of chess is recommended as a school activity. In addition to requiring that individuals become actively involved in a mentally demanding competition, its effects are stimulating, wholesome, and healthy. Several benefits accrue from the teaching and promoting of chess in schools. Chess limits the element of luck (teaching the importance of…

  14. A novel theoretical probe of the SrTiO3 surface under water-splitting conditions

    NASA Astrophysics Data System (ADS)

    Letchworth-Weaver, Kendra; Gunceler, Deniz; Arias, Tomás; Plaza, Manuel; Huang, Xin; Brock, Joel; Rodriguez-López, Joaquin; Abruña, Hector

    2014-03-01

    Understanding the reaction mechanisms required to generate hydrogen fuel by photoelectrolysis of water is essential to energy conversion research. These reaction pathways are strongly influenced by the geometry and electronic structure of the electrode surface under water-splitting conditions. Electrochemical microscopy has demonstrated that biasing a SrTiO3 (001) surface can lead to an increase in water-splitting activity. In operando X-ray reflectivity measurements at the Cornell High Energy Synchrotron Source (CHESS) correlate this increase in activity to a significant reorganization in the surface structure but are unable to determine the exact nature of this change. Joint Density-Functional Theory (JDFT), a rigorous yet computationally efficient alternative to molecular dynamics, provides a quantum-mechanical description of an electrode surface in contact with an aqueous environment, and a microscopically detailed description of the interfacial liquid structure. Our JDFT calculations determine the structure of the activated SrTiO3 surface and explore why it is correlated with higher activity for water splitting. With no empirical parameters whatsoever, we predict the X-ray crystal truncation rods for SrTiO3, finding excellent agreement with experiment. Funded by the Energy Materials Center at Cornell (EMC2).

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Philipp, Hugh T., E-mail: htp2@cornell.edu; Tate, Mark W.; Purohit, Prafull

    Modern storage rings are readily capable of providing intense x-ray pulses, tens of picoseconds in duration, millions of times per second. Exploiting the temporal structure of these x-ray sources opens avenues for studying rapid structural changes in materials. Many processes (e.g. crack propagation, deformation on impact, turbulence, etc.) differ in detail from one sample trial to the next and would benefit from the ability to record successive x-ray images with single x-ray sensitivity while framing at 5 to 10 MHz rates. To this end, we have pursued the development of fast x-ray imaging detectors capable of collecting bursts of imagesmore » that enable the isolation of single synchrotron bunches and/or bunch trains. The detector technology used is the hybrid pixel array detector (PAD) with a charge integrating front-end, and high-speed, in-pixel signal storage elements. A 384×256 pixel version, the Keck-PAD, with 150 µm × 150 µm pixels and 8 dedicated in-pixel storage elements is operational, has been tested at CHESS, and has collected data for compression wave studies. An updated version with 27 dedicated storage capacitors and identical pixel size has been fabricated.« less

  16. Compact Undulator for the Cornell High Energy Synchrotron Source: Design and Beam Test Results

    NASA Astrophysics Data System (ADS)

    Temnykh, A.; Dale, D.; Fontes, E.; Li, Y.; Lyndaker, A.; Revesz, P.; Rice, D.; Woll, A.

    2013-03-01

    We developed, built and beam tested a novel, compact, in-vacuum undulator magnet based on an adjustable phase (AP) scheme. The undulator is 1 m long with a 5mm gap. It has a pure permanent magnet structure with 24.4mm period and 1.1 Tesla maximum peak field. The device consists of two planar magnet arrays mounted on rails inside of a rectangular box-like frame with 156 mm × 146 mm dimensions. The undulator magnet is enclosed in a 273 mm (10.75") diameter cylindrical vacuum vessel with a driver mechanism placed outside. In May 2012 the CHESS Compact Undulator (CCU) was installed in Cornell Electron Storage Ring and beam tested. During four weeks of dedicated run we evaluated undulator radiation properties as well as magnetic, mechanical and vacuum properties of the undulator magnet. We also studied the effect of the CCU on storage ring beam. The spectral characteristics and intensity of radiation were found to be in very good agreement with expected. The magnet demonstrated reproducibility of undulator parameter K at 1.4 × 10-4 level. It was also found that the undulator K. parameter change does not affect electron beam orbit and betatron tunes.

  17. More Than a Game: Eight Transition Lessons Chess Teaches.

    ERIC Educational Resources Information Center

    Kennedy, Mark

    1998-01-01

    Chess is an interactive, authentic, three-dimensional activity that naturally supports and encourages marginalized students in successful transitions. Chess can also help educators gain a wider understanding of what it means to be, and who is perceived to be, intelligent. Discusses eight specific ways in which chess can be beneficial in an…

  18. Chess and Education.

    ERIC Educational Resources Information Center

    Horgan, Dianne; Morgan, David

    Aspects of chess relevant to certain educational issues are explored. Based on findings from a sample of about 50 children from 6 to 18 years of age, discussion focuses on (1) how children play chess and how the process of acquiring expertise differs among children and adults, (2) chess training techniques and why they are effective with children,…

  19. Revising superior planning performance in chess players: the impact of time restriction and motivation aspects.

    PubMed

    Unterrainer, Josef Martin; Kaller, Christoph Philipp; Leonhart, Rainer; Rahm, Benjamin

    2011-01-01

    In a previous study (Unterrainer, Kaller, Halsband, & Rahm, 2006), chess players outperformed non-chess players in the Tower of London planning task but exhibited disproportionately longer processing times. This pattern of results raises the question of whether chess players' planning capabilities are superior or whether the results reflect differences in the speed-accuracy trade-off between the groups, possibly attributable to sports motivation. The present study was designed to disambiguate these alternative suggestions by implementing various constraints on planning time and by assessing self-reported motivation. In contrast to the previous study, chess players' performance was not superior, independently of whether problems had to be solved with (Experiment 1) or without (Experiment 2) time limits. As expected, chess players reported higher overall trait and state motivation scores across both experiments. These findings revise the notion of superior planning performance in chess players. In consequence, they do not conform with the assumption of a general transfer of chess-related planning expertise to other cognitive domains, instead suggesting that superior performance may be possible only under specific circumstances such as receiving competitive instructions.

  20. Use of Biotechnological Devices in the Quantification of Psychophysiological Workload of Professional Chess Players.

    PubMed

    Fuentes, Juan P; Villafaina, Santos; Collado-Mateo, Daniel; de la Vega, Ricardo; Gusi, Narcis; Clemente-Suárez, Vicente Javier

    2018-01-19

    Psychophysiological requirements of chess players are poorly understood, and periodization of training is often made without any empirical basis. For this reason, the aim of the present study was to investigate the psychophysiological response and quantify the player internal load during, and after playing a chess game. The participant was an elite 33 year-old male chess player ranked among the 300 best chess players in the world. Thus, cortical arousal by critical flicker fusion threshold, electroencephalogram by the theta Fz/alpha Pz ratio and autonomic modulation by heart rate variability were analyzed. Data revealed that cortical arousal by critical flicker fusion threshold and theta Fz/alpha Pz ratio increased and heart rate variability decreased during chess game. All these changes indicated that internal load increased during the chess game. In addition, pre-activation was detected in pre-game measure, suggesting that the prefrontal cortex might be preparatory activated. For these reasons, electroencephalogram, critical flicker fusion threshold and heart rate variability analysis may be highly applicable tools to control and monitor workload in chess player.

  1. Mechanisms and neural basis of object and pattern recognition: a study with chess experts.

    PubMed

    Bilalić, Merim; Langner, Robert; Erb, Michael; Grodd, Wolfgang

    2010-11-01

    Comparing experts with novices offers unique insights into the functioning of cognition, based on the maximization of individual differences. Here we used this expertise approach to disentangle the mechanisms and neural basis behind two processes that contribute to everyday expertise: object and pattern recognition. We compared chess experts and novices performing chess-related and -unrelated (visual) search tasks. As expected, the superiority of experts was limited to the chess-specific task, as there were no differences in a control task that used the same chess stimuli but did not require chess-specific recognition. The analysis of eye movements showed that experts immediately and exclusively focused on the relevant aspects in the chess task, whereas novices also examined irrelevant aspects. With random chess positions, when pattern knowledge could not be used to guide perception, experts nevertheless maintained an advantage. Experts' superior domain-specific parafoveal vision, a consequence of their knowledge about individual domain-specific symbols, enabled improved object recognition. Functional magnetic resonance imaging corroborated this differentiation between object and pattern recognition and showed that chess-specific object recognition was accompanied by bilateral activation of the occipitotemporal junction, whereas chess-specific pattern recognition was related to bilateral activations in the middle part of the collateral sulci. Using the expertise approach together with carefully chosen controls and multiple dependent measures, we identified object and pattern recognition as two essential cognitive processes in expert visual cognition, which may also help to explain the mechanisms of everyday perception.

  2. Strategic intensity: a conversation with world chess champion Garry Kasparov.

    PubMed

    Kasparov, Garry

    2005-04-01

    It's hard to find a better exemplar for competition than chess. The image of two brilliant minds locked in a battle of skill and will-in which chance plays little or no apparent role-is compelling. Even people who have scant knowledge of the game instinctively recognize that chess is unusual in terms of its intellectual complexity and the strategic demands it places on players. Can strategists learn anything from chess players about what it takes to win? To find out, H BR senior editor Diane L. Coutu talked with Garry Kasparov, the world's number one player since 1984. Kasparov believes that success in both chess and business is very much a question of psychological advantage; the complexity of the game demands that players rely heavily on their instincts and on gamesmanship. In this wide-ranging interview, Kasparov explores the power of chess as a model for business competition; the balance that chess players strike between intuition and analysis; the significance of his loss to IBM's chess-playing computer, Deep Blue; and how his legendary rivalry with Anatoly Karpov, Kasparov's predecessor as World Chess Champion, affected his own success. Kasparov also shares his solution to what he calls the champion's dilemma, a question for all world masters, whether they are in business, sports, or chess: Where does a virtuoso go after he has accomplished everything he's ever wanted to, even beyond his wildest imagination? If you are lucky, says Kasparov, your enemies will push you to be passionate about staying at the top.

  3. Want to Improve Your Leadership Skills? Play Chess!

    ERIC Educational Resources Information Center

    Hunt, Samuel J.; Cangemi, Joseph

    2014-01-01

    This paper explores the value of the "Game of Kings," Chess, as a tool for developing highly successful leaders. This paper highlights and demonstrates how the methods of the game of Chess can have strong influence on the ability and performance of exceptional leaders in any field, and how the game of Chess can enhance the cognitive…

  4. The Gymnasium of the Mind: Teaching Chess in Early Childhood

    ERIC Educational Resources Information Center

    Costello, Patrick J. M.

    2013-01-01

    The central aim of this paper is to undertake a critical review of arguments which propose that chess should be taught in schools and other educational settings. In particular, I offer an answer to the question: "Should chess be taught in early childhood?" Many claims have been made about the educational benefits of chess instruction. In…

  5. Does Chess Need Intelligence?--A Study with Young Chess Players

    ERIC Educational Resources Information Center

    Bilalic, Merim; McLeod, Peter; Gobet, Fernand

    2007-01-01

    Although it is widely acknowledged that chess is the best example of an intellectual activity among games, evidence showing the association between any kind of intellectual ability and chess skill has been remarkably sparse. One of the reasons is that most of the studies investigated only one factor (e.g., intelligence), neglecting other factors…

  6. A multimodal MRI dataset of professional chess players.

    PubMed

    Li, Kaiming; Jiang, Jing; Qiu, Lihua; Yang, Xun; Huang, Xiaoqi; Lui, Su; Gong, Qiyong

    2015-01-01

    Chess is a good model to study high-level human brain functions such as spatial cognition, memory, planning, learning and problem solving. Recent studies have demonstrated that non-invasive MRI techniques are valuable for researchers to investigate the underlying neural mechanism of playing chess. For professional chess players (e.g., chess grand masters and masters or GM/Ms), what are the structural and functional alterations due to long-term professional practice, and how these alterations relate to behavior, are largely veiled. Here, we report a multimodal MRI dataset from 29 professional Chinese chess players (most of whom are GM/Ms), and 29 age matched novices. We hope that this dataset will provide researchers with new materials to further explore high-level human brain functions.

  7. School-age children talk about chess: does knowledge drive syntactic complexity?

    PubMed

    Nippold, Marilyn A

    2009-08-01

    This study examined language productivity and syntactic complexity in school-age children in relation to their knowledge of the topic of discussion-the game of chess. Children (N = 32; mean age = 10;11 [years;months]) who played chess volunteered to be interviewed by an adult examiner who had little or no experience playing chess. Children's chess knowledge and experience was assessed, and each child was classified as a novice or an expert player. Each child participated in 3 speaking tasks: General Conversation, Chess Conversation, and Chess Explanation. Interviews were audiorecorded, transcribed into Systematic Analysis of Language Transcripts (J. F. Miller & R. Chapman, 2003), segmented into T-units, and coded for finite clauses. Each speaking task was analyzed for total T-units; mean length of T-unit; clausal density; and nominal, relative, and adverbial clause use. Total T-units, mean length of T-unit, clausal density, and the use of each type of subordinate clause was substantially higher in the Chess Explanation task compared with the Chess Conversation task or the General Conversation task. Compared with the novices, the experts knew more about chess, had played longer, and were stronger players. Nevertheless, the novices and experts did not differ on any of the language factors for any of the speaking tasks. Language productivity and syntactic complexity in school-age children are strongly influenced by the speaking task. When children are presented with a motivating and challenging topic, they rise to the occasion to explain the finer details of it to a naïve adult.

  8. The Effect of Self-Explanation and Prediction on the Development of Principled Understanding of Chess in Novices

    ERIC Educational Resources Information Center

    de Bruin, Anique B. H.; Rikers, Remy M. J. P.; Schmidt, Henk G.

    2007-01-01

    The present study was designed to test the effect of self-explanation and prediction on the development of principled understanding of novices learning to play chess. First-year psychology students, who had no chess experience, first learned the basic rules of chess and were afterwards divided in three conditions. They either observed (control…

  9. Chess Revision: Acquiring the Rules of Chess Variants through FOL Theory Revision from Examples

    NASA Astrophysics Data System (ADS)

    Muggleton, Stephen; Paes, Aline; Santos Costa, Vítor; Zaverucha, Gerson

    The game of chess has been a major testbed for research in artificial intelligence, since it requires focus on intelligent reasoning. Particularly, several challenges arise to machine learning systems when inducing a model describing legal moves of the chess, including the collection of the examples, the learning of a model correctly representing the official rules of the game, covering all the branches and restrictions of the correct moves, and the comprehensibility of such a model. Besides, the game of chess has inspired the creation of numerous variants, ranging from faster to more challenging or to regional versions of the game. The question arises if it is possible to take advantage of an initial classifier of chess as a starting point to obtain classifiers for the different variants. We approach this problem as an instance of theory revision from examples. The initial classifier of chess is inspired by a FOL theory approved by a chess expert and the examples are defined as sequences of moves within a game. Starting from a standard revision system, we argue that abduction and negation are also required to best address this problem. Experimental results show the effectiveness of our approach.

  10. Innovation and nested preferential growth in chess playing behavior

    NASA Astrophysics Data System (ADS)

    Perotti, J. I.; Jo, H.-H.; Schaigorodsky, A. L.; Billoni, O. V.

    2013-11-01

    Complexity develops via the incorporation of innovative properties. Chess is one of the most complex strategy games, where expert contenders exercise decision making by imitating old games or introducing innovations. In this work, we study innovation in chess by analyzing how different move sequences are played at the population level. It is found that the probability of exploring a new or innovative move decreases as a power law with the frequency of the preceding move sequence. Chess players also exploit already known move sequences according to their frequencies, following a preferential growth mechanism. Furthermore, innovation in chess exhibits Heaps' law suggesting similarities with the process of vocabulary growth. We propose a robust generative mechanism based on nested Yule-Simon preferential growth processes that reproduces the empirical observations. These results, supporting the self-similar nature of innovations in chess are important in the context of decision making in a competitive scenario, and extend the scope of relevant findings recently discovered regarding the emergence of Zipf's law in chess.

  11. Does playing blindfold chess reduce the quality of game: comments on chabris and hearst (2003).

    PubMed

    Jeremic, Veljko; Vukmirovic, Dragan; Radojicic, Zoran

    2010-01-01

    Blindfold chess is a special type of chess game where both the board and pieces are not visible to its players. This paper aims to determine whether the quality of the game played blindfolded is lower than when played under normal conditions. The best chess program was used to analyze games played by the world's top Grandmasters under both conditions. We have analyzed the Monaco 1993-1998 data set introduced by Chabris and Hearst (2003). The results showed that although a larger number of mistakes occurred while playing blindfolded, no significant statistical difference between the rapid and blindfold games has been found. Nevertheless, by applying the same methodology to the Monaco 2002-2007 data set a substantial difference between the blindfold and the rapid chess game was noticed. In this paper, we have addressed the possible improvement of the chess game quality and the advances in chess programs that may be responsible for detecting more blunders. Copyright © 2009 Cognitive Science Society, Inc.

  12. Sex differences in intellectual performance: analysis of a large cohort of competitive chess players.

    PubMed

    Chabris, Christopher F; Glickman, Mark E

    2006-12-01

    Only 1% of the world's chess grandmasters are women. This underrepresentation is unlikely to be caused by discrimination, because chess ratings objectively reflect competitive results. Using data on the ratings of more than 250,000 tournament players over 13 years, we investigated several potential explanations for the male domination of elite chess. We found that (a) the ratings of men are higher on average than those of women, but no more variable; (b) matched boys and girls improve and drop out at equal rates, but boys begin chess competition in greater numbers and at higher performance levels than girls; and (c) in locales where at least 50% of the new young players are girls, their initial ratings are not lower than those of boys. We conclude that the greater number of men at the highest levels in chess can be explained by the greater number of boys who enter chess at the lowest levels.

  13. Exploring the use patterns of a mobile health application for alcohol addiction before the initial lapse after detoxification.

    PubMed

    Chih, Ming-Yuan

    2014-01-01

    How patients used Addiction-Comprehensive Health Enhancement Support System (A-CHESS)1, a mobile health intervention, while quitting drinking is worthy exploring. This study is to explore A-CHESS use patterns prior to the initial lapse reported after discharge from inpatient detoxification programs. 142 patients with alcohol addiction from two treatment agencies in the U.S. were included. A comprehensive set of A-CHESS use measures were developed based on a three-level system use framework and three A-CHESS service categories. In latent profile analyses, three A-CHESS system use patterns-inactive, passive, and active users-were found. Compared to the passive users (with the highest chance of the initial lapse), the active users (with the lowest chance of such behavior) participated more in online social activities, used more sessions, viewed more pages, and used A-CHESS longer. However, the chances of the initial lapse between A-CHESS user profiles were not statistically different. Implications of this finding were provided.

  14. Chess masters show a hallmark of face processing with chess.

    PubMed

    Boggan, Amy L; Bartlett, James C; Krawczyk, Daniel C

    2012-02-01

    Face processing has several distinctive hallmarks that researchers have attributed either to face-specific mechanisms or to extensive experience distinguishing faces. Here, we examined the face-processing hallmark of selective attention failure--as indexed by the congruency effect in the composite paradigm--in a domain of extreme expertise: chess. Among 27 experts, we found that the congruency effect was equally strong with chessboards and faces. Further, comparing these experts with recreational players and novices, we observed a trade-off: Chess expertise was positively related to the congruency effect with chess yet negatively related to the congruency effect with faces. These and other findings reveal a case of expertise-dependent, facelike processing of objects of expertise and suggest that face and expert-chess recognition share common processes.

  15. Fat suppression at three-dimensional T1-weighted MR imaging of the hands: Dixon method versus CHESS technique.

    PubMed

    Kirchgesner, T; Perlepe, V; Michoux, N; Larbi, A; Vande Berg, B

    2018-01-01

    To compare the effectiveness of fat suppression and the image quality of the Dixon method with those of the chemical shift-selective (CHESS) technique in hands of normal subjects at non-enhanced three-dimensional (3D) T1-weighted MR imaging. Both hands of 14 healthy volunteers were imaged with 3D fast spoiled gradient echo (FSPGR) T1-weighted Dixon, 3D FSPGR T1-weighted CHESS and 3D T1-weighted fast spin echo (FSE) CHESS sequences in a 1.5T MR scanner. Three radiologists scored the effectiveness of fat suppression in bone marrow (EFS BM ) and soft tissues (EFS ST ) in 20 joints per subject. One radiologist measured the signal-to-noise ratio (SNR) in 10 bones per subject. Statistical analysis used two-way ANOVA with random effects (P<0.0083), paired t-test (P<0.05) and observed agreement to assess differences in effectiveness of fat suppression, differences in SNR and interobserver agreement. EFS BM was statistically significantly higher for the 3D FSPGR T1-weighted Dixon than for the 3D FSPGR T1-weighted CHESS sequence and the 3D FSE T1-weighted CHESS sequence (P<0.0001). EFS ST was statistically significantly higher for the 3D FSPGR T1-weighted Dixon than for the 3D FSPGR T1-weighted CHESS sequence (P<0.0011) and for the 3D FSE T1-weighted CHESS sequence in the axial plane (P=0.0028). Mean SNR was statistically significantly higher for 3D FSPGR T1-weighted Dixon sequence than for 3D FSPGR T1-weighted CHESS and 3D FSE T1-weighted CHESS sequences (P<0.0001). The Dixon method yields more effective fat suppression and higher SNR than the CHESS technique at 3D T1-weighted MR imaging of the hands. Copyright © 2017 Éditions françaises de radiologie. Published by Elsevier Masson SAS. All rights reserved.

  16. The temporo-parietal junction contributes to global gestalt perception-evidence from studies in chess experts.

    PubMed

    Rennig, Johannes; Bilalić, Merim; Huberle, Elisabeth; Karnath, Hans-Otto; Himmelbach, Marc

    2013-01-01

    In a recent neuroimaging study the comparison of intact vs. disturbed perception of global gestalt indicated a significant role of the temporo-parietal junction (TPJ) in the intact perception of global gestalt (Huberle and Karnath, 2012). This location corresponded well with the areas known to be damaged or impaired in patients with simultanagnosia after stroke or due to neurodegenerative diseases. It was concluded that the TPJ plays an important role in the integration of individual items to a holistic percept. Thus, increased BOLD signals should be found in this region whenever a task calls for the integration of multiple visual items. Behavioral experiments in chess experts suggested that their superior skills in comparison to chess novices are partly based on fast holistic processing of chess positions with multiple pieces. We thus analyzed BOLD data from four fMRI studies that compared chess experts with chess novices during the presentation of complex chess-related visual stimuli (Bilalić et al., 2010, 2011a,b, 2012). Three regions of interests were defined by significant TPJ clusters in the abovementioned study of global gestalt perception (Huberle and Karnath, 2012) and BOLD signal amplitudes in these regions were compared between chess experts and novices. These cross-paradigm ROI analyses revealed higher signals at the TPJ in chess experts in comparison to novices during presentations of complex chess positions. This difference was consistent across the different tasks in five independent experiments. Our results confirm the assumption that the TPJ region identified in previous work on global gestalt perception plays an important role in the processing of complex visual stimulus configurations.

  17. The temporo-parietal junction contributes to global gestalt perception—evidence from studies in chess experts

    PubMed Central

    Rennig, Johannes; Bilalić, Merim; Huberle, Elisabeth; Karnath, Hans-Otto; Himmelbach, Marc

    2013-01-01

    In a recent neuroimaging study the comparison of intact vs. disturbed perception of global gestalt indicated a significant role of the temporo-parietal junction (TPJ) in the intact perception of global gestalt (Huberle and Karnath, 2012). This location corresponded well with the areas known to be damaged or impaired in patients with simultanagnosia after stroke or due to neurodegenerative diseases. It was concluded that the TPJ plays an important role in the integration of individual items to a holistic percept. Thus, increased BOLD signals should be found in this region whenever a task calls for the integration of multiple visual items. Behavioral experiments in chess experts suggested that their superior skills in comparison to chess novices are partly based on fast holistic processing of chess positions with multiple pieces. We thus analyzed BOLD data from four fMRI studies that compared chess experts with chess novices during the presentation of complex chess-related visual stimuli (Bilalić et al., 2010, 2011a,b, 2012). Three regions of interests were defined by significant TPJ clusters in the abovementioned study of global gestalt perception (Huberle and Karnath, 2012) and BOLD signal amplitudes in these regions were compared between chess experts and novices. These cross-paradigm ROI analyses revealed higher signals at the TPJ in chess experts in comparison to novices during presentations of complex chess positions. This difference was consistent across the different tasks in five independent experiments. Our results confirm the assumption that the TPJ region identified in previous work on global gestalt perception plays an important role in the processing of complex visual stimulus configurations. PMID:24009574

  18. Does Fat Suppression via Chemically Selective Saturation (CHESS) Affect R2*-MRI for Transfusional Iron Overload Assessment? A Clinical Evaluation at 1.5 and 3 Tesla

    PubMed Central

    Krafft, Axel J.; Loeffler, Ralf B.; Song, Ruitian; Bian, Xiao; McCarville, M. Beth; Hankins, Jane S.; Hillenbrand, Claudia M.

    2015-01-01

    Purpose Fat suppression (FS) via chemically selective saturation (CHESS) eliminates fat-water oscillations in multi-echo gradient echo (mGRE) R2*-MRI. However, for increasing R2* values as seen with increasing liver iron content (LIC), the water signal spectrally overlaps with the CHESS band, which may alter R2*. Here, we investigate the effect of CHESS on R2* and describe a heuristic correction for the observed CHESS-induced R2* changes. Methods Eighty patients (49/31 female/male, mean age: 18.3±11.7 years) with iron overload were scanned with a non-FS and a CHESS-FS mGRE sequence at 1.5T and 3T. Mean liver R2* values were evaluated using 3 published fitting approaches. Measured and model-corrected R2* values were compared and statistically analyzed. Results At 1.5T, CHESS led to a systematic R2* reduction (P<0.001 for all fitting algorithms) especially toward higher R2*. Our model described the observed changes well and reduced the CHESS-induced R2* bias after correction (linear regression slopes: 1.032/0.927/0.981). No CHESS-induced R2* reductions were found at 3T. Conclusion The CHESS-induced R2* bias at 1.5T needs to be considered when applying R2*-LIC biopsy calibrations for clinical LIC assessment which were established without FS at 1.5T. The proposed model corrects the R2* bias and could therefore improve clinical iron overload assessment based on linear R2*-LIC calibrations. PMID:26308155

  19. An Investigation on the Effectiveness of Chess Training on Creativity and Theory of Mind Development at Early Childhood

    ERIC Educational Resources Information Center

    Sigirtmac, Ayperi Dikici

    2016-01-01

    In recent years, chess training is offered as a compulsory elective course in some pre-schools, whereas it is not offered in some other pre-schools. There are children who attend chess clubs outside of schools. Chess is considered to be a game of intelligence, and its effects on individuals have been the subject of many researches. This study was…

  20. Assessing Threat Detection Scenarios through Hypothesis Generation and Testing

    DTIC Science & Technology

    2015-12-01

    task of playing chess with that of diagnosing medical conditions. Whereas both chess players and physicians must recognize patterns among a fixed...additional cues, all while maintaining these details in memory. Thus, the common research finding that chess experts can hold and process more information...of General Psychology, 124, 19-34. Chase, W. G., & Simon, H. A. (1973). Perception in chess . Cognitive Psychology, 4, 55-81. Choi, E., & Lee

  1. Comprehensive Investigation of White Matter Tracts in Professional Chess Players and Relation to Expertise: Region of Interest and DMRI Connectometry.

    PubMed

    Mayeli, Mahsa; Rahmani, Farzaneh; Aarabi, Mohammad Hadi

    2018-01-01

    Purpose: Expertise is the product of training. Few studies have used functional connectivity or conventional diffusometric methods to identify neural underpinnings of chess expertise. Diffusometric variables of white matter might reflect these adaptive changes, along with changes in structural connectivity, which is a sensitive measure of microstructural changes. Method: Diffusometric variables of 29 professional chess players and 29 age-sex matched controls were extracted for white matter regions based on John Hopkin's Mori white matter atlas and partially correlated against professional training time and level of chess proficiency. Diffusion MRI connectometry was implemented to identify changes in structural connectivity in professional players compared to novices. Result: Compared to novices, higher planar anisotropy (CP) was observed in inferior longitudinal fasciculus (ILF), superior longitudinal fasciculus (SLF) and cingulate gyrus, in professional chess players, which correlated with higher RPM score in this group. Higher fractional anisotropy (FA) was observed in ILF, uncinate fasciculus (UF) and hippocampus and correlated with better scores in Raven's progressive matrices (RPM) score and longer duration of chess training in professional players. Consistently, radial diffusivity in bilateral IFOF, bilateral ILF and bilateral SLF was inversely correlated with level of training in professional players. DMRI connectometry analysis identified increased connectivity in bilateral UF, bilateral IFOF, bilateral cingulum, and corpus callosum in chess player's compared to controls. Conclusion: Structural connectivity of major associational subcortical white matter fibers are increased in professional chess players. FA and CP of ILF, SLF and UF directly correlates with duration of professional training and RPM score, in professional chess players.

  2. Comprehensive Investigation of White Matter Tracts in Professional Chess Players and Relation to Expertise: Region of Interest and DMRI Connectometry

    PubMed Central

    Mayeli, Mahsa; Rahmani, Farzaneh; Aarabi, Mohammad Hadi

    2018-01-01

    Purpose: Expertise is the product of training. Few studies have used functional connectivity or conventional diffusometric methods to identify neural underpinnings of chess expertise. Diffusometric variables of white matter might reflect these adaptive changes, along with changes in structural connectivity, which is a sensitive measure of microstructural changes. Method: Diffusometric variables of 29 professional chess players and 29 age-sex matched controls were extracted for white matter regions based on John Hopkin's Mori white matter atlas and partially correlated against professional training time and level of chess proficiency. Diffusion MRI connectometry was implemented to identify changes in structural connectivity in professional players compared to novices. Result: Compared to novices, higher planar anisotropy (CP) was observed in inferior longitudinal fasciculus (ILF), superior longitudinal fasciculus (SLF) and cingulate gyrus, in professional chess players, which correlated with higher RPM score in this group. Higher fractional anisotropy (FA) was observed in ILF, uncinate fasciculus (UF) and hippocampus and correlated with better scores in Raven's progressive matrices (RPM) score and longer duration of chess training in professional players. Consistently, radial diffusivity in bilateral IFOF, bilateral ILF and bilateral SLF was inversely correlated with level of training in professional players. DMRI connectometry analysis identified increased connectivity in bilateral UF, bilateral IFOF, bilateral cingulum, and corpus callosum in chess player's compared to controls. Conclusion: Structural connectivity of major associational subcortical white matter fibers are increased in professional chess players. FA and CP of ILF, SLF and UF directly correlates with duration of professional training and RPM score, in professional chess players. PMID:29773973

  3. Fat suppression at 2D MR imaging of the hands: Dixon method versus CHESS technique and STIR sequence.

    PubMed

    Kirchgesner, Thomas; Perlepe, Vasiliki; Michoux, Nicolas; Larbi, Ahmed; Vande Berg, Bruno

    2017-04-01

    To compare the effectiveness of fat suppression and the signal-to-noise ratio (SNR) of the Dixon method with those of the CHESS (Chemical Shift-Selective) technique and STIR (Short Tau Inversion Recovery) sequence in hands of normal subjects at 2D MR imaging. 14 healthy volunteers (mean age of 29.4 years) consented to have both hands prospectively imaged with SE T1 Dixon, T1 CHESS, T2 Dixon, T2 CHESS and STIR sequences in a 1.5T MR scanner. Three radiologists scored the effectiveness of fat suppression in bone marrow (EFS BM ) and soft tissues (EFS ST ) in 20 joints per subject. One radiologist measured the SNR in 10 bones per subject. Statistical analysis used two-way ANOVA with random effects, paired t-test and observed agreement to assess differences in effectiveness of fat suppression, differences in SNR and inter-observer agreement. EFS BM was statistically significantly higher for T1 Dixon than for T1 CHESS and for T2 Dixon than for T2 CHESS (p<0.0001). EFS BM was significantly higher for T2 Dixon than for STIR in the coronal plane (p=0.0020). The SNR was significantly higher for T1 Dixon than for T1 CHESS and for T2 Dixon than for STIR (p<0.0001). The SNR was significantly lower for T2 Dixon than for T2 CHESS (p<0.0001). The Dixon method yields more effective fat suppression and higher SNR than the CHESS technique at 2D T1-weighted MR imaging of the hands. At T2-weighted MR imaging, fat suppression is more effective with the Dixon method while SNR is higher with the CHESS technique. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Response time distributions in rapid chess: a large-scale decision making experiment.

    PubMed

    Sigman, Mariano; Etchemendy, Pablo; Slezak, Diego Fernández; Cecchi, Guillermo A

    2010-01-01

    Rapid chess provides an unparalleled laboratory to understand decision making in a natural environment. In a chess game, players choose consecutively around 40 moves in a finite time budget. The goodness of each choice can be determined quantitatively since current chess algorithms estimate precisely the value of a position. Web-based chess produces vast amounts of data, millions of decisions per day, incommensurable with traditional psychological experiments. We generated a database of response times (RTs) and position value in rapid chess games. We measured robust emergent statistical observables: (1) RT distributions are long-tailed and show qualitatively distinct forms at different stages of the game, (2) RT of successive moves are highly correlated both for intra- and inter-player moves. These findings have theoretical implications since they deny two basic assumptions of sequential decision making algorithms: RTs are not stationary and can not be generated by a state-function. Our results also have practical implications. First, we characterized the capacity of blunders and score fluctuations to predict a player strength, which is yet an open problem in chess softwares. Second, we show that the winning likelihood can be reliably estimated from a weighted combination of remaining times and position evaluation.

  5. Response Time Distributions in Rapid Chess: A Large-Scale Decision Making Experiment

    PubMed Central

    Sigman, Mariano; Etchemendy, Pablo; Slezak, Diego Fernández; Cecchi, Guillermo A.

    2010-01-01

    Rapid chess provides an unparalleled laboratory to understand decision making in a natural environment. In a chess game, players choose consecutively around 40 moves in a finite time budget. The goodness of each choice can be determined quantitatively since current chess algorithms estimate precisely the value of a position. Web-based chess produces vast amounts of data, millions of decisions per day, incommensurable with traditional psychological experiments. We generated a database of response times (RTs) and position value in rapid chess games. We measured robust emergent statistical observables: (1) RT distributions are long-tailed and show qualitatively distinct forms at different stages of the game, (2) RT of successive moves are highly correlated both for intra- and inter-player moves. These findings have theoretical implications since they deny two basic assumptions of sequential decision making algorithms: RTs are not stationary and can not be generated by a state-function. Our results also have practical implications. First, we characterized the capacity of blunders and score fluctuations to predict a player strength, which is yet an open problem in chess softwares. Second, we show that the winning likelihood can be reliably estimated from a weighted combination of remaining times and position evaluation. PMID:21031032

  6. Rise of Human Intelligence: Comments on Howard (1999).

    ERIC Educational Resources Information Center

    Gobet, Fernand; Campitelli, Guillermo; Waters, Andrew J.

    2002-01-01

    Finds several difficulties with the theory advanced by R. Howard and shows that alternative explanations relating to changes in the chess environment, including increased access to chess knowledge, offer better explanations for the increased presence of young players at top-level chess. (SLD)

  7. Playing Chess Unconsciously

    ERIC Educational Resources Information Center

    Kiesel, Andrea; Kunde, Wilfried; Pohl, Carsten; Berner, Michael P.; Hoffmann, Joachim

    2009-01-01

    Expertise in a certain stimulus domain enhances perceptual capabilities. In the present article, the authors investigate whether expertise improves perceptual processing to an extent that allows complex visual stimuli to bias behavior unconsciously. Expert chess players judged whether a target chess configuration entailed a checking configuration.…

  8. Chess-playing epilepsy: a case report with video-EEG and back averaging.

    PubMed

    Mann, M W; Gueguen, B; Guillou, S; Debrand, E; Soufflet, C

    2004-12-01

    A patient suffering from juvenile myoclonic epilepsy experienced myoclonic jerks, fairly regularly, while playing chess. The myoclonus appeared particularly when he had to plan his strategy, to choose between two solutions or while raising the arm to move a chess figure. Video-EEG-polygraphy was performed, with back averaging of the myoclonus registered during a chess match and during neuropsychological testing with Kohs cubes. The EEG spike wave complexes were localised in the fronto-central region. [Published with video sequences].

  9. Does fat suppression via chemically selective saturation affect R2*-MRI for transfusional iron overload assessment? A clinical evaluation at 1.5T and 3T.

    PubMed

    Krafft, Axel J; Loeffler, Ralf B; Song, Ruitian; Bian, Xiao; McCarville, M Beth; Hankins, Jane S; Hillenbrand, Claudia M

    2016-08-01

    Fat suppression (FS) via chemically selective saturation (CHESS) eliminates fat-water oscillations in multiecho gradient echo (mGRE) R2*-MRI. However, for increasing R2* values as seen with increasing liver iron content (LIC), the water signal spectrally overlaps with the CHESS band, which may alter R2*. We investigated the effect of CHESS on R2* and developed a heuristic correction for the observed CHESS-induced R2* changes. Eighty patients [female, n = 49; male, n = 31; mean age (± standard deviation), 18.3 ± 11.7 y] with iron overload were scanned with a non-FS and a CHESS-FS mGRE sequence at 1.5T and 3T. Mean liver R2* values were evaluated using three published fitting approaches. Measured and model-corrected R2* values were compared and statistically analyzed. At 1.5T, CHESS led to a systematic R2* reduction (P < 0.001 for all fitting algorithms) especially toward higher R2*. Our model described the observed changes well and reduced the CHESS-induced R2* bias after correction (linear regression slopes: 1.032/0.927/0.981). No CHESS-induced R2* reductions were found at 3T. The CHESS-induced R2* bias at 1.5T needs to be considered when applying R2*-LIC biopsy calibrations for clinical LIC assessment, which were established without FS at 1.5T. The proposed model corrects the R2* bias and could therefore improve clinical iron overload assessment based on linear R2*-LIC calibrations. Magn Reson Med 76:591-601, 2016. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.

  10. Analysis of layer-by-layer thin-film oxide growth using RHEED and Atomic Force Microscopy

    NASA Astrophysics Data System (ADS)

    Adler, Eli; Sullivan, M. C.; Gutierrez-Llorente, Araceli; Joress, H.; Woll, A.; Brock, J. D.

    2015-03-01

    Reflection high energy electron diffraction (RHEED) is commonly used as an in situ analysis tool for layer-by-layer thin-film growth. Atomic force microscopy is an equally common ex situ tool for analysis of the film surface, providing visual evidence of the surface morphology. During growth, the RHEED intensity oscillates as the film surface changes in roughness. It is often assumed that the maxima of the RHEED oscillations signify a complete layer, however, the oscillations in oxide systems can be misleading. Thus, using only the RHEED maxima is insufficient. X-ray reflectivity can also be used to analyze growth, as the intensity oscillates in phase with the smoothness of the surface. Using x-ray reflectivity to determine the thin film layer deposition, we grew three films where the x-ray and RHEED oscillations were nearly exactly out of phase and halted deposition at different points in the growth. Pre-growth and post-growth AFM images emphasize the fact that the maxima in RHEED are not a justification for determining layer completion. Work conducted at the Cornell High Energy Synchrotron Source (CHESS) supported by NSF Awards DMR-1332208 and DMR-0936384 and the Cornell Center for Materials Research Shared Facilities are supported through DMR-1120296.

  11. Chess therapy: A new approach to curing panic attack.

    PubMed

    Barzegar, Kazem; Barzegar, Somayeh

    2017-12-01

    To study the effect of playing cell phone chess game on treating panic attack. The chess game on an android cell phone was played by the researcher who was affected by panic attack as a post-traumatic disorder immediately after or before feeling of the start of symptoms. The right level of difficulty, i.e., levels 2-4, was selected for optimal results. Playing chess game on the android cell phone prevented the manifestation of panic attack and led to the cure of this traumatic condition. Chess therapy with the right level of difficulty can be recommended as a very effective non-pharmaceutical method for the successful treatment of panic attacks. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. The third flight of CHESS: Preliminary analysis of interstellar H2 on the β1 Sco sightline

    NASA Astrophysics Data System (ADS)

    Kruczek, Nick; France, Kevin

    2018-01-01

    We describe the scientific motivation and technical development of the Colorado High-resolution Echelle Stellar Spectrograph (CHESS), focusing on the preliminary science results for the third launch of the payload (CHESS-3). CHESS is a far ultraviolet rocket-borne instrument designed to study the atomic-to-molecular transitions within translucent cloud regions in the interstellar medium. CHESS is an objective echelle spectrograph, which uses a mechanically-ruled echelle and a powered (f/12.4) cross-dispersing grating, and is designed to achieve a resolving power R > 100,000 over the band pass λλ 1000-1600 Å. CHESS-3 launched on 14 June 2017 aboard NASA/CU sounding rocket mission 36.323 UG. The target for the flight was β1 Sco, a B1V star with a sightline that is likely sampling translucent material. We present flight results of interstellar molecular hydrogen excitation, including initial measurements of the column density and temperature, on the sightline.

  13. Does Far Transfer Exist? Negative Evidence From Chess, Music, and Working Memory Training.

    PubMed

    Sala, Giovanni; Gobet, Fernand

    2017-12-01

    Chess masters and expert musicians appear to be, on average, more intelligent than the general population. Some researchers have thus claimed that playing chess or learning music enhances children's cognitive abilities and academic attainment. We here present two meta-analyses assessing the effect of chess and music instruction on children's cognitive and academic skills. A third meta-analysis evaluated the effects of working memory training-a cognitive skill correlated with music and chess expertise-on the same variables. The results show small to moderate effects. However, the effect sizes are inversely related to the quality of the experimental design (e.g., presence of active control groups). This pattern of results casts serious doubts on the effectiveness of chess, music, and working memory training. We discuss the theoretical and practical implications of these findings; extend the debate to other types of training such as spatial training, brain training, and video games; and conclude that far transfer of learning rarely occurs.

  14. Teaching Beginning Chess Skills to Students with Disabilities.

    ERIC Educational Resources Information Center

    Storey, Keith

    2000-01-01

    This article discusses teaching higher-level thinking skills and concentration to students with disabilities through chess instruction. Guidelines for chess instruction are provided, including: teaching ideas and strategy first rather than specific lines of play, using a variety of instructional modalities, and building in reinforcement for…

  15. Teaching Chess to Young Children.

    ERIC Educational Resources Information Center

    Bankauskas, Deborah

    2000-01-01

    Presents suggestions for teaching chess to young children as part of the problem-solving component of a kindergarten mathematics curriculum. Discusses the introduction of pairs of chess characters, playing challenge games with teachers to enhance skill development, and writing down the rules of the game. Notes that children's problem-solving and…

  16. The Chess and Mathematics Connection: More than Just a Game

    ERIC Educational Resources Information Center

    Berkman, Robert M.

    2004-01-01

    This article describes connections between chess and mathematics, including examples of activities that connect chess with set theory, patterns, algebra, geometry, combinatorics, and Pascal's triangle. The author observes that competitive games play a dual purpose in advancing the work of mathematics educators: to reinforce a specific skill and to…

  17. Is chess the drosophila of artificial intelligence? A social history of an algorithm.

    PubMed

    Ensmenger, Nathan

    2012-02-01

    Since the mid 1960s, researchers in computer science have famously referred to chess as the 'drosophila' of artificial intelligence (AI). What they seem to mean by this is that chess, like the common fruit fly, is an accessible, familiar, and relatively simple experimental technology that nonetheless can be used productively to produce valid knowledge about other, more complex systems. But for historians of science and technology, the analogy between chess and drosophila assumes a larger significance. As Robert Kohler has ably described, the decision to adopt drosophila as the organism of choice for genetics research had far-reaching implications for the development of 20th century biology. In a similar manner, the decision to focus on chess as the measure of both human and computer intelligence had important and unintended consequences for AL research. This paper explores the emergence of chess as an experimental technology, its significance in the developing research practices of the AI community, and the unique ways in which the decision to focus on chess shaped the program of AI research in the decade of the 1970s. More broadly, it attempts to open up the virtual black box of computer software--and of computer games in particular--to the scrutiny of historical and sociological analysis.

  18. A compact high brightness laser synchrotron light source for medical applications

    NASA Astrophysics Data System (ADS)

    Nakajima, Kazuhisa

    1999-07-01

    The present high-brightness hard X-ray sources have been developed as third generation synchrotron light sources based on large high energy electron storage rings and magnetic undulators. Recently availability of compact terawatt lasers arouses a great interest in the use of lasers as undulators. The laser undulator concept makes it possible to construct an attractive compact synchrotron radiation source which has been proposed as a laser synchrotron light source. This paper proposes a compact laser synchrotron light source for mediacal applications, such as an intravenous coronary angiography and microbeam therapy.

  19. Community Health Environment Scan Survey (CHESS): a novel tool that captures the impact of the built environment on lifestyle factors.

    PubMed

    Wong, Fiona; Stevens, Denise; O'Connor-Duffany, Kathleen; Siegel, Karen; Gao, Yue

    2011-03-07

    Novel efforts and accompanying tools are needed to tackle the global burden of chronic disease. This paper presents an approach to describe the environments in which people live, work, and play. Community Health Environment Scan Survey (CHESS) is an empirical assessment tool that measures the availability and accessibility, of healthy lifestyle options lifestyle options. CHESS reveals existing community assets as well as opportunities for change, shaping community intervention planning efforts by focusing on community-relevant opportunities to address the three key risk factors for chronic disease (i.e. unhealthy diet, physical inactivity, and tobacco use). The CHESS tool was developed following a review of existing auditing tools and in consultation with experts. It is based on the social-ecological model and is adaptable to diverse settings in developed and developing countries throughout the world. For illustrative purposes, baseline results from the Community Interventions for Health (CIH) Mexico site are used, where the CHESS tool assessed 583 food stores and 168 restaurants. Comparisons between individual-level survey data from schools and community-level CHESS data are made to demonstrate the utility of the tool in strategically guiding intervention activities. The environments where people live, work, and play are key factors in determining their diet, levels of physical activity, and tobacco use. CHESS is the first tool of its kind that systematically and simultaneously examines how built environments encourage/discourage healthy eating, physical activity, and tobacco use. CHESS can help to design community interventions to prevent chronic disease and guide healthy urban planning. © 2011 Fiona Wong et al.

  20. The Clinical Health Economics System Simulation (CHESS): a teaching tool for systems- and practice-based learning.

    PubMed

    Voss, John D; Nadkarni, Mohan M; Schectman, Joel M

    2005-02-01

    Academic medical centers face barriers to training physicians in systems- and practice-based learning competencies needed to function in the changing health care environment. To address these problems, at the University of Virginia School of Medicine the authors developed the Clinical Health Economics System Simulation (CHESS), a computerized team-based quasi-competitive simulator to teach the principles and practical application of health economics. CHESS simulates treatment costs to patients and society as well as physician reimbursement. It is scenario based with residents grouped into three teams, each team playing CHESS using differing (fee-for-service or capitated) reimbursement models. Teams view scenarios and select from two or three treatment options that are medically justifiable yet have different potential cost implications. CHESS displays physician reimbursement and patient and societal costs for each scenario as well as costs and income summarized across all scenarios extrapolated to a physician's entire patient panel. The learners are asked to explain these findings and may change treatment options and other variables such as panel size and case mix to conduct sensitivity analyses in real time. Evaluations completed in 2003 by 68 (94%) CHESS resident and faculty participants at 19 U.S. residency programs preferred CHESS to a traditional lecture-and-discussion format to learn about medical decision making, physician reimbursement, patient costs, and societal costs. Ninety-eight percent reported increased knowledge of health economics after viewing the simulation. CHESS demonstrates the potential of computer simulation to teach health economics and other key elements of practice- and systems-based competencies.

  1. The Role of Domain-Specific Practice, Handedness, and Starting Age in Chess

    ERIC Educational Resources Information Center

    Gobet, Fernand; Campitelli, Guillermo

    2007-01-01

    The respective roles of the environment and innate talent have been a recurrent question for research into expertise. The authors investigated markers of talent, environment, and critical period for the acquisition of expert performance in chess. Argentinian chess players (N = 104), ranging from weak amateurs to grandmasters, completed a…

  2. Cognitive Effects of Chess Instruction on Students at Risk for Academic Failure

    ERIC Educational Resources Information Center

    Hong, Saahoon; Bart, William M.

    2007-01-01

    Cognitive effects of chess instruction on students at risk for academic failure was examined. Thirty-eight students, from three elementary schools, participated in this study. The experimental group received a ninety-minute chess lesson once per week over a three-month period; and the control group students regularly attended school activities…

  3. Improving International-Level Chess Players' Performance with an Acceptance-Based Protocol: Preliminary Findings

    ERIC Educational Resources Information Center

    Ruiz, Francisco J.; Luciano, Carmen

    2012-01-01

    This study compared an individual, 4-hr intervention based on acceptance and commitment therapy (ACT) versus a no-contact control condition in improving the performance of international-level chess players. Five participants received the brief ACT protocol, with each matched to another chess player with similar characteristics in the control…

  4. Graduation 2010: The Chess Component of Critical Thinking.

    ERIC Educational Resources Information Center

    Englehardt, Cathy Willis; Hauser, Brenda Bennett

    This paper describes the chess program for elementary school students in the Daviess County School District, Kentucky. The Critical Thinking committee of the school system's Graduation 2010 initiative explored various ways to promote critical thinking in the classroom and arrived at a program to put chess boards in the classrooms and to encourage…

  5. How to Teach Chess in the Public Schools: A Course Outline.

    ERIC Educational Resources Information Center

    Schmidt, Bernard

    Educational objectives and course outlines for beginning, intermediate, and advanced chess instruction in elementary and secondary schools are provided. Objectives are that students will develop analytical, synthetic, and decision-making skills, learn to engage in thorough chess research that will enhance their ability to do any research, and gain…

  6. Check This, Mate: Chess Moves Kids.

    ERIC Educational Resources Information Center

    Vail, Kathleen

    1995-01-01

    According to Irene Dixon-Darnell, a 75-year-old great-grandmother who runs a chess-education program in the Washoe (Nevada) County Schools, chess can win-over some difficult students. She believes the ancient game of strategy teaches children to focus, encourages them to think critically and creatively, and even cures emotional wounds. Research…

  7. Artistic Chess

    ERIC Educational Resources Information Center

    Blackwood, Christine Horvatis

    2011-01-01

    Chess is one of the world's oldest games, invented in India before 600 AD. The original pieces were inspired by the infantry, cavalry, elephants, and chariots of the ancient Indian army. The design of chess pieces changed when the game spread to the West, reflecting the society of medieval Europe. The king remained, pawns were the foot soldiers,…

  8. Helping students mathematical construction on square and rectangle’s area by using Sarong motive chess

    NASA Astrophysics Data System (ADS)

    Zuliana, Eka; Setyawan, Fariz; Veloo, Arsaythamby

    2017-12-01

    The aim of this study is developing the learning trajectory to construct students’ understanding of the concept of the area of square and rectangle by using Sarong Motive Chess. This research is a design research which is consists of three stages. The stages are preparing for the experiment, designing experiment, and making a retrospective analysis. The activities started by the activity of using sarong motive chess as the manipulative measurement unit. The Sarong motive chess helps students to understand the concept of area of square and rectangle. In the formal stage of cognitive level, students estimate the area of square and rectangle by determining the square unit at the surface area of sarong through many ways. The result of this study concludes that Sarong motive chess can be used for mathematics learning process. It helps the students to construct the concept of a square and rectangle’s area. This study produces learning trajectory to construct the concept of a square and rectangle’s area by using Sarong motive chess, especially for elementary school students.

  9. Your move: The effect of chess on mathematics test scores

    PubMed Central

    Rosholm, Michael; Mikkelsen, Mai Bjørnskov; Gumede, Kamilla

    2017-01-01

    We analyse the effect of substituting a weekly mathematics lesson in primary school grades 1–3 with a lesson in mathematics based on chess instruction. We use data from the City of Aarhus in Denmark, combining test score data with a comprehensive data set obtained from administrative registers. We use two different methodological approaches to identify and estimate treatment effects and we tend to find positive effects, indicating that knowledge acquired through chess play can be transferred to the domain of mathematics. We also find larger impacts for unhappy children and children who are bored in school, perhaps because chess instruction facilitates learning by providing an alternative approach to mathematics for these children. The results are encouraging and suggest that chess may be an important and effective tool for improving mathematical capacity in young students. PMID:28494023

  10. Your move: The effect of chess on mathematics test scores.

    PubMed

    Rosholm, Michael; Mikkelsen, Mai Bjørnskov; Gumede, Kamilla

    2017-01-01

    We analyse the effect of substituting a weekly mathematics lesson in primary school grades 1-3 with a lesson in mathematics based on chess instruction. We use data from the City of Aarhus in Denmark, combining test score data with a comprehensive data set obtained from administrative registers. We use two different methodological approaches to identify and estimate treatment effects and we tend to find positive effects, indicating that knowledge acquired through chess play can be transferred to the domain of mathematics. We also find larger impacts for unhappy children and children who are bored in school, perhaps because chess instruction facilitates learning by providing an alternative approach to mathematics for these children. The results are encouraging and suggest that chess may be an important and effective tool for improving mathematical capacity in young students.

  11. Synchrotron Radiation Research--An Overview.

    ERIC Educational Resources Information Center

    Bienenstock, Arthur; Winick, Herman

    1983-01-01

    Discusses expanding user community seeking access to synchrotron radiation sources, properties/sources of synchrotron radiation, permanent-magnet technology and its impact on synchrotron radiation research, factors limiting power, the density of synchrotron radiation, and research results illustrating benefit of higher flux and brightness. Also…

  12. Comparison of the effects of the CHESS sequence and the SPAIR sequence for fat saturation

    NASA Astrophysics Data System (ADS)

    Dong, Kyung-Rae; Goo, Eun-Hoe; Kweon, Dae-Cheol; Chung, Woon-Kwan; Lee, Jong-Woong

    2013-06-01

    This study compared the abilities of the chemical-shift selective saturation(CHESS) and the spectrally-adiabatic inversion recovery (SPAIR) fat-saturation techniques to resolve the recent problems in fat saturation caused by areas of changing volume such as the head and the neck and by metal artifacts when T1 fat-saturation techniques representing the anatomical images and T2 fat-saturation techniques representing pathological images are used. To compare the abilities of CHESS and SPAIR, we acquired images of the head and the neck and of the pelvis, and we compared the contrast-to-noise ratios (CNRs) and the signal-to-noise ratios (SNRs) of the signals from the flexed body parts. Images were taken of the abdomens, heads and necks, and pelvises of 15 men and 15 women (30 in total). In all scanning techniques, the SNRs and the CNRs were calculated based on a quantitative analysis method with a view to obtaining uniform data. According to the study results, the CNRs of the SPAIR and the CHESS techniques for the pelvis in the T1-weighted image were 55.10 and 67.23, respectively. The SNRs of the SPAIR technique were70.61 for muscle and 15.50 for fat whereas the SNRs of the CHESS technique were 79.23 for muscle and 12.00 for fat. For the pelvis in the T2-weighted image, the CNRs of the SPAIR and the CHESS technique were 12.50 and 16.66, respectively. The SNRs of the SPAIR technique were 16.98 for muscle and 5.14 for fat. In contrast, the SNRs of the CHESS technique were 27.90 for muscle and 11.23 for fat. Consequently, the signal intensity was higher in the CHESS than in the SPAIR technique. Nevertheless, with regard to the clinical usefulness, the image quality was higher in the SPAIR technique than in the CHESS technique.

  13. Successful Organizational Strategies to Sustain Use of A-CHESS: A Mobile Intervention for Individuals With Alcohol Use Disorders.

    PubMed

    Ford, James H; Alagoz, Esra; Dinauer, Susan; Johnson, Kimberly A; Pe-Romashko, Klaren; Gustafson, David H

    2015-08-18

    Mobile health (mHealth) services are growing in importance in health care research with the advancement of wireless networks, tablets, and mobile phone technologies. These technologies offer a wide range of applications that cover the spectrum of health care delivery. Although preliminary experiments in mHealth demonstrate promising results, more robust real-world evidence is needed for widespread adoption and sustainment of these technologies. Our aim was to identify the problems/challenges associated with sustained use of an mHealth addiction recovery support app and to determine strategies used by agencies that successfully sustained client use of A-CHESS. Qualitative inquiry assessed staff perceptions about organizational attributes and strategies associated with sustained use of the mobile app, A-CHESS. A total of 73 interviews of clinicians and administrators were conducted. The initial interviews (n=36) occurred at the implementation of A-CHESS. Follow-up interviews (n=37) occurred approximately 12 and 24 months later. A coding scheme was developed and Multiuser NVivo was used to manage and analyze the blinded interview data. Successful strategies used by treatment providers to sustain A-CHESS included (1) strong leadership support, (2) use of client feedback reports to follow up on non-engaged clients, (3) identify passionate staff and incorporate A-CHESS discussions in weekly meetings, (4) develop A-CHESS guidelines related to client use, (5) establish internal work groups to engage clients, and (6) establish a financial strategy to sustain A-CHESS use. The study also identified attributes of A-CHESS that enhanced as well as inhibited its sustainability. Mobile apps can play an important role in health care delivery. However, providers will need to develop strategies for engaging both staff and patients in ongoing use of the apps. They will also need to rework business processes to accommodate the changes in communication frequency and style, learn to use app data for decision making, and identify financing mechanisms for supporting these changes.

  14. Chess Evolution Visualization.

    PubMed

    Lu, Wei-Li; Wang, Yu-Shuen; Lin, Wen-Chieh

    2014-05-01

    We present a chess visualization to convey the changes in a game over successive generations. It contains a score chart, an evolution graph and a chess board, such that users can understand a game from global to local viewpoints. Unlike current graphical chess tools, which focus only on highlighting pieces that are under attack and require sequential investigation, our visualization shows potential outcomes after a piece is moved and indicates how much tactical advantage the player can have over the opponent. Users can first glance at the score chart to roughly obtain the growth and decline of advantages from both sides, and then examine the position relations and the piece placements, to know how the pieces are controlled and how the strategy works. To achieve this visualization, we compute the decision tree using artificial intelligence to analyze a game, in which each node represents a chess position and each edge connects two positions that are one-move different. We then merge nodes representing the same chess position, and shorten branches where nodes on them contain only two neighbors, in order to achieve readability. During the graph rendering, the nodes containing events such as draws, effective checks and checkmates, are highlighted because they show how a game is ended. As a result, our visualization helps players understand a chess game so that they can efficiently learn strategies and tactics. The presented results, evaluations, and the conducted user studies demonstrate the feasibility of our visualization design.

  15. Use of the interRAI CHESS scale to predict mortality among persons with neurological conditions in three care settings.

    PubMed

    Hirdes, John P; Poss, Jeffrey W; Mitchell, Lori; Korngut, Lawrence; Heckman, George

    2014-01-01

    Persons with certain neurological conditions have higher mortality rates than the population without neurological conditions, but the risk factors for increased mortality within diagnostic groups are less well understood. The interRAI CHESS scale has been shown to be a strong predictor of mortality in the overall population of persons receiving health care in community and institutional settings. This study examines the performance of CHESS as a predictor of mortality among persons with 11 different neurological conditions. Survival analyses were done with interRAI assessments linked to mortality data among persons in home care (n = 359,940), complex continuing care hospitals/units (n = 88,721), and nursing homes (n = 185,309) in seven Canadian provinces/territories. CHESS was a significant predictor of mortality in all 3 care settings for the 11 neurological diagnostic groups considered after adjusting for age and sex. The distribution of CHESS scores varied between diagnostic groups and within diagnostic groups in different care settings. CHESS is a valid predictor of mortality in neurological populations in community and institutional care. It may prove useful for several clinical, administrative, policy-development, evaluation and research purposes. Because it is routinely gathered as part of normal clinical practice in jurisdictions (like Canada) that have implemented interRAI assessment instruments, CHESS can be derived without additional need for data collection.

  16. Inhibition of irrelevant information is not necessary to performance of expert chess players.

    PubMed

    Postal, Virginie

    2012-08-01

    Some studies on expertise have demonstrated that the difference between novices and experts can be partly due to a lack of knowledge about which information is relevant for a given situation. This lack of knowledge seems to be associated with the selection of correct information and with inhibitory processes. However, while the efficiency of inhibitory processes can lead to better performance in the normal population, it seems that experts in chess do not base their performance on this process but rather on an automatic and parallel encoding of information. Two experiments investigated the processes involved in a check detection task. The congruence of the information was manipulated in a Stroop situation similar to Reingold, Charness, Scheltetus, & Stampe (2001). The results showed that the experts did not benefit from cuing with a congruent cue and that they did not show any interference effect by the incongruent cue, contrary to less skilled chess players who benefited from cuing (Exp. 1). An attentional priming procedure confirmed the automatic encoding of chess relations in the more skilled chess players by showing no advantage from the prime in this group (Exp. 2). Taken together, the results indicate that the processing was serial for the less skilled chess players and that it was automatic and parallel for the more expert chess players. The inhibition of irrelevant information does not seem necessary to process information rapidly and efficiently.

  17. The Role of Practice in Chess: A Longitudinal Study

    ERIC Educational Resources Information Center

    Campitelli, Guillermo; Gobet, Fernand

    2008-01-01

    We investigated the role of practice in the acquisition of chess expertise by submitting a questionnaire to 104 players of different skill levels. Players had to report their chess rating, the number of hours of individual and group practice, their use of different learning resources and activities, and whether they had been trained by a coach.…

  18. School-Age Children Talk about Chess: Does Knowledge Drive Syntactic Complexity?

    ERIC Educational Resources Information Center

    Nippold, Marilyn A.

    2009-01-01

    Purpose: This study examined language productivity and syntactic complexity in school-age children in relation to their knowledge of the topic of discussion--the game of chess. Method: Children (N = 32; mean age = 10;11 [years;months]) who played chess volunteered to be interviewed by an adult examiner who had little or no experience playing…

  19. The re-flight of the Colorado high-resolution Echelle stellar spectrograph (CHESS): improvements, calibrations, and post-flight results

    NASA Astrophysics Data System (ADS)

    Hoadley, Keri; France, Kevin; Kruczek, Nicholas; Fleming, Brian; Nell, Nicholas; Kane, Robert; Swanson, Jack; Green, James; Erickson, Nicholas; Wilson, Jacob

    2016-07-01

    In this proceeding, we describe the scientific motivation and technical development of the Colorado High- resolution Echelle Stellar Spectrograph (CHESS), focusing on the hardware advancements and testing supporting the second flight of the payload (CHESS-2). CHESS is a far ultraviolet (FUV) rocket-borne instrument designed to study the atomic-to-molecular transitions within translucent cloud regions in the interstellar medium (ISM). CHESS is an objective f/12.4 echelle spectrograph with resolving power > 100,000 over the band pass 1000 - 1600 Å. The spectrograph was designed to employ an R2 echelle grating with "low" line density. We compare the FUV performance of experimental echelle etching processes (lithographically by LightSmyth, Inc. and etching via electron-beam technology by JPL Microdevices Laboratory) with traditional, mechanically-ruled gratings (Bach Research, Inc. and Richardson Gratings). The cross-dispersing grating, developed and ruled by Horiba Jobin-Yvon, is a holographically-ruled, "low" line density, powered optic with a toroidal surface curvature. Both gratings were coated with aluminum and lithium fluoride (Al+LiF) at Goddard Space Flight Center (GSFC). Results from final efficiency and reflectivity measurements for the optical components of CHESS-2 are presented. CHESS-2 utilizes a 40mm-diameter cross-strip anode readout microchannel plate (MCP) detector fabricated by Sensor Sciences, Inc., to achieve high spatial resolution with high count rate capabilities (global rates 1 MHz). We present pre-flight laboratory spectra and calibration results. CHESS-2 launched on 21 February 2016 aboard NASA/CU sounding rocket mission 36.297 UG. We observed the intervening ISM material along the sightline to epsilon Per and present initial characterization of the column densities, temperature, and kinematics of atomic and molecular species in the observation.

  20. The neural correlates of theory of mind and their role during empathy and the game of chess: A functional magnetic resonance imaging study.

    PubMed

    Powell, Joanne L; Grossi, Davide; Corcoran, Rhiannon; Gobet, Fernand; García-Fiñana, Marta

    2017-07-04

    Chess involves the capacity to reason iteratively about potential intentional choices of an opponent and therefore involves high levels of explicit theory of mind [ToM] (i.e. ability to infer mental states of others) alongside clear, strategic rule-based decision-making. Functional magnetic resonance imaging was used on 12 healthy male novice chess players to identify cortical regions associated with chess, ToM and empathizing. The blood-oxygenation-level-dependent (BOLD) response for chess and empathizing tasks was extracted from each ToM region. Results showed neural overlap between ToM, chess and empathizing tasks in right-hemisphere temporo-parietal junction (TPJ) [BA40], left-hemisphere superior temporal gyrus [BA22] and posterior cingulate gyrus [BA23/31]. TPJ is suggested to underlie the capacity to reason iteratively about another's internal state in a range of tasks. Areas activated by ToM and empathy included right-hemisphere orbitofrontal cortex and bilateral middle temporal gyrus: areas that become active when there is need to inhibit one's own experience when considering the internal state of another and for visual evaluation of action rationality. Results support previous findings, that ToM recruits a neural network with each region sub-serving a supporting role depending on the nature of the task itself. In contrast, a network of cortical regions primarily located within right- and left-hemisphere medial-frontal and parietal cortex, outside the internal representational network, was selectively recruited during the chess task. We hypothesize that in our cohort of novice chess players the strategy was to employ an iterative thinking pattern which in part involved mentalizing processes and recruited core ToM-related regions. Copyright © 2017. Published by Elsevier Ltd.

  1. The CHESS method of forensic opinion formulation: striving to checkmate bias.

    PubMed

    Wills, Cheryl D

    2008-01-01

    Expert witnesses use various methods to render dispassionate opinions. Some forensic psychiatrists acknowledge bias up front; other experts use principles endorsed by the American Academy of Psychiatry and the Law or other professional organizations. This article introduces CHESS, a systematic method for reducing bias in expert opinions. The CHESS method involves identifying a Claim or preliminary opinion; developing a Hierarchy of supporting evidence; examining the evidence for weaknesses or areas of Exposure; Studying and revising the claim and supporting evidence; and Synthesizing a revised opinion. Case examples illustrate how the CHESS method may help experts reduce bias while strengthening opinions. The method also helps experts prepare for court by reminding them to anticipate questions that may be asked during cross-examination. The CHESS method provides a framework for formulating, revising, and identifying limitations of opinions, which allows experts to incorporate neutrality into forensic opinions.

  2. Impact of Chess Training on Mathematics Performance and Concentration Ability of Children with Learning Disabilities

    ERIC Educational Resources Information Center

    Scholz, Markus; Niesch, Harald; Steffen, Olaf; Ernst, Baerbel; Loeffler, Markus; Witruk, Evelin; Schwarz, Hans

    2008-01-01

    The aim of this study is to evaluate the benefit of chess in mathematics lessons for children with learning disabilities based on lower intelligence (IQ 70-85). School classes of four German schools for children with learning disabilities were randomly assigned to receive one hour of chess lesson instead of one hour of regular mathematics lessons…

  3. Does Chess Training Affect Conceptual Development of Six-Year-Old Children in Turkey?

    ERIC Educational Resources Information Center

    Sigirtmac, Ayperi Dikici

    2012-01-01

    Many studies propose that chess is a game requiring cognitive skills and has positive effects on mental development. In recent years, chess training has also been emphasised as important during the early childhood period. However, no studies have been done with six-year-old children. The purpose of this study was to investigate whether or not…

  4. Relative Age Effects in a Cognitive Task: A Case Study of Youth Chess

    ERIC Educational Resources Information Center

    Helsen, Werner F.; Baker, Joseph; Schorer, Joerg; Steingröver, Christina; Wattie, Nick; Starkes, Janet L.

    2016-01-01

    The relative age effect (RAE) has been demonstrated in many youth and professional sports. In this study, we hypothesized that there would also be a RAE among youth chess players who are typically involved in a complex cognitive task without significant physical requirements. While typical RAEs have been observed in adult chess players, in this…

  5. Rapid directed evolution of stabilized proteins with cellular high-throughput encapsulation solubilization and screening (CHESS).

    PubMed

    Yong, K J; Scott, D J

    2015-03-01

    Directed evolution is a powerful method for engineering proteins towards user-defined goals and has been used to generate novel proteins for industrial processes, biological research and drug discovery. Typical directed evolution techniques include cellular display, phage display, ribosome display and water-in-oil compartmentalization, all of which physically link individual members of diverse gene libraries to their translated proteins. This allows the screening or selection for a desired protein function and subsequent isolation of the encoding gene from diverse populations. For biotechnological and industrial applications there is a need to engineer proteins that are functional under conditions that are not compatible with these techniques, such as high temperatures and harsh detergents. Cellular High-throughput Encapsulation Solubilization and Screening (CHESS), is a directed evolution method originally developed to engineer detergent-stable G proteins-coupled receptors (GPCRs) for structural biology. With CHESS, library-transformed bacterial cells are encapsulated in detergent-resistant polymers to form capsules, which serve to contain mutant genes and their encoded proteins upon detergent mediated solubilization of cell membranes. Populations of capsules can be screened like single cells to enable rapid isolation of genes encoding detergent-stable protein mutants. To demonstrate the general applicability of CHESS to other proteins, we have characterized the stability and permeability of CHESS microcapsules and employed CHESS to generate thermostable, sodium dodecyl sulfate (SDS) resistant green fluorescent protein (GFP) mutants, the first soluble proteins to be engineered using CHESS. © 2014 Wiley Periodicals, Inc.

  6. The SLICE, CHESS, and SISTINE Ultraviolet Spectrographs: Rocket-Borne Instrumentation Supporting Future Astrophysics Missions

    NASA Astrophysics Data System (ADS)

    France, Kevin; Hoadley, Keri; Fleming, Brian T.; Kane, Robert; Nell, Nicholas; Beasley, Matthew; Green, James C.

    2016-03-01

    NASA’s suborbital program provides an opportunity to conduct unique science experiments above Earth’s atmosphere and is a pipeline for the technology and personnel essential to future space astrophysics, heliophysics, and atmospheric science missions. In this paper, we describe three astronomy payloads developed (or in development) by the Ultraviolet Rocket Group at the University of Colorado. These far-ultraviolet (UV) (100-160nm) spectrographic instruments are used to study a range of scientific topics, from gas in the interstellar medium (accessing diagnostics of material spanning five orders of magnitude in temperature in a single observation) to the energetic radiation environment of nearby exoplanetary systems. The three instruments, Suborbital Local Interstellar Cloud Experiment (SLICE), Colorado High-resolution Echelle Stellar Spectrograph (CHESS), and Suborbital Imaging Spectrograph for Transition region Irradiance from Nearby Exoplanet host stars (SISTINE) form a progression of instrument designs and component-level technology maturation. SLICE is a pathfinder instrument for the development of new data handling, storage, and telemetry techniques. CHESS and SISTINE are testbeds for technology and instrument design enabling high-resolution (R>105) point source spectroscopy and high throughput imaging spectroscopy, respectively, in support of future Explorer, Probe, and Flagship-class missions. The CHESS and SISTINE payloads support the development and flight testing of large-format photon-counting detectors and advanced optical coatings: NASA’s top two technology priorities for enabling a future flagship observatory (e.g. the LUVOIR Surveyor concept) that offers factors of ˜50-100 gain in UV spectroscopy capability over the Hubble Space Telescope. We present the design, component level laboratory characterization, and flight results for these instruments.

  7. Strategy and Sociability: The Mind, the Body, and the Soul of Chess

    ERIC Educational Resources Information Center

    Fine, Gary Alan

    2014-01-01

    Chess is a game of minds, bodies, and emotions. Most players recognize each of these as essential to playful competition, and all three are embedded in social relations. Thus chess, despite its reputation as a game of the mind, is not only a deeply thoughtful exercise, but also a test of physical endurance and strong emotions in its joys and…

  8. Successful Organizational Strategies to Sustain Use of A-CHESS: A Mobile Intervention for Individuals With Alcohol Use Disorders

    PubMed Central

    Alagoz, Esra; Dinauer, Susan; Johnson, Kimberly A; Pe-Romashko, Klaren; Gustafson, David H

    2015-01-01

    Background Mobile health (mHealth) services are growing in importance in health care research with the advancement of wireless networks, tablets, and mobile phone technologies. These technologies offer a wide range of applications that cover the spectrum of health care delivery. Although preliminary experiments in mHealth demonstrate promising results, more robust real-world evidence is needed for widespread adoption and sustainment of these technologies. Objective Our aim was to identify the problems/challenges associated with sustained use of an mHealth addiction recovery support app and to determine strategies used by agencies that successfully sustained client use of A-CHESS. Methods Qualitative inquiry assessed staff perceptions about organizational attributes and strategies associated with sustained use of the mobile app, A-CHESS. A total of 73 interviews of clinicians and administrators were conducted. The initial interviews (n=36) occurred at the implementation of A-CHESS. Follow-up interviews (n=37) occurred approximately 12 and 24 months later. A coding scheme was developed and Multiuser NVivo was used to manage and analyze the blinded interview data. Results Successful strategies used by treatment providers to sustain A-CHESS included (1) strong leadership support, (2) use of client feedback reports to follow up on non-engaged clients, (3) identify passionate staff and incorporate A-CHESS discussions in weekly meetings, (4) develop A-CHESS guidelines related to client use, (5) establish internal work groups to engage clients, and (6) establish a financial strategy to sustain A-CHESS use. The study also identified attributes of A-CHESS that enhanced as well as inhibited its sustainability. Conclusions Mobile apps can play an important role in health care delivery. However, providers will need to develop strategies for engaging both staff and patients in ongoing use of the apps. They will also need to rework business processes to accommodate the changes in communication frequency and style, learn to use app data for decision making, and identify financing mechanisms for supporting these changes. PMID:26286257

  9. Improved CHESS imaging with the use of rice pads: Investigation in the neck, shoulder, and elbow.

    PubMed

    Moriya, Susumu; Miki, Yukio; Yokobayashi, Tsuneo; Yamamoto, Akira; Kanagaki, Mitsunori; Komori, Yoshiaki; Fujimoto, Koji; Ishikawa, Mitsunori

    2010-06-01

    To investigate the feasibility of rice pads for improving nonuniform fat suppression in magnetic resonance imaging (MRI) of the neck, shoulder, and elbow using the chemical shift selective (CHESS) technique. CHESS imaging of the neck, shoulder, and elbow was performed on 10 healthy volunteers with and without the use of rice pads. Images were visually assessed by one radiologist and one radiologic technologist using a four-point scale. Results were compared using Wilcoxon's signed rank sum test. Images with and without rice pads were rated 3.9 and 1.5 for the neck (P = 0.002), 3.85 and 2.5 for the shoulder (P = 0.002), and 3.4 and 2.45 for the elbow (P = 0.004). Fat-suppressed images obtained using the CHESS technique were significantly improved by rice pads for the neck, shoulder, and elbow, indicating that image deterioration with CHESS caused by magnetic field nonuniformity can be improved by rice pads in all body areas.

  10. [The Triumph of "Stupidity" : Deep Blue`s Victory over Garri Kasparov. The Controversy about its Impact on Artficial Intelligence Research].

    PubMed

    Heßler, Martina

    2017-03-01

    The competition between the chess computer Deep Blue and the former chess world champion Garri Kasparov in 1997 was a spectacle staged for the media. However, the chess game, like other games, was also a test field for artificial intelligence research. On the one hand Deep Blue's victory was called a "milestone" for AI research, on the other hand, a dead end, since the superiority of the chess computer was based on pure computing power and had nothing to do with "real" AI.The article questions the premises of these different interpretations and maps Deep Blue and its way of playing chess into the history of AI. This also requires an analysis of the underlying concepts of thinking. Finally, the essay calls for assuming different "ways of thinking" for man and computer. Instead of fundamental discussions of concepts of thinking, we should ask about the consequences of the human-machine division of labor.

  11. Predicting In-Situ X-ray Diffraction for the SrTiO3/Liquid Interface from First Principles

    NASA Astrophysics Data System (ADS)

    Letchworth-Weaver, Kendra; Gunceler, Deniz; Sundararaman, Ravishankar; Huang, Xin; Brock, Joel; Arias, T. A.

    2013-03-01

    Recent advances in experimental techniques, such as in-situ x-ray diffraction, allow researchers to probe the solid-liquid interface in electrochemical systems under operating conditions. These advances offer an unprecedented opportunity for theory to predict properties of electrode materials in aqueous environments and inform the design of energy conversion and storage devices. To compare with experiment, these theoretical studies require microscopic details of both the liquid and the electrode surface. Joint Density Functional Theory (JDFT), a computationally efficient alternative to molecular dynamics, couples a classical density-functional, which captures molecular structure of the liquid, to a quantum-mechanical functional for the electrode surface. We present a JDFT exploration of SrTiO3, which can catalyze solar-driven water splitting, in an electrochemical environment. We determine the geometry of the polar SrTiO3 surface and the equilibrium structure of the contacting liquid, as well as the influence of the liquid upon the electronic structure of the surface. We then predict the effect of the fluid environment on x-ray diffraction patterns and compare our predictions to in-situ measurements performed at the Cornell High Energy Synchrotron Source (CHESS). This material is based upon work supported by the Energy Materials Center at Cornell (EMC2), an Energy Frontier Research Center funded by the U.S. Department of Energy.

  12. Chess databases as a research vehicle in psychology: Modeling large data.

    PubMed

    Vaci, Nemanja; Bilalić, Merim

    2017-08-01

    The game of chess has often been used for psychological investigations, particularly in cognitive science. The clear-cut rules and well-defined environment of chess provide a model for investigations of basic cognitive processes, such as perception, memory, and problem solving, while the precise rating system for the measurement of skill has enabled investigations of individual differences and expertise-related effects. In the present study, we focus on another appealing feature of chess-namely, the large archive databases associated with the game. The German national chess database presented in this study represents a fruitful ground for the investigation of multiple longitudinal research questions, since it collects the data of over 130,000 players and spans over 25 years. The German chess database collects the data of all players, including hobby players, and all tournaments played. This results in a rich and complete collection of the skill, age, and activity of the whole population of chess players in Germany. The database therefore complements the commonly used expertise approach in cognitive science by opening up new possibilities for the investigation of multiple factors that underlie expertise and skill acquisition. Since large datasets are not common in psychology, their introduction also raises the question of optimal and efficient statistical analysis. We offer the database for download and illustrate how it can be used by providing concrete examples and a step-by-step tutorial using different statistical analyses on a range of topics, including skill development over the lifetime, birth cohort effects, effects of activity and inactivity on skill, and gender differences.

  13. Does chess instruction improve mathematical problem-solving ability? Two experimental studies with an active control group.

    PubMed

    Sala, Giovanni; Gobet, Fernand

    2017-12-01

    It has been proposed that playing chess enables children to improve their ability in mathematics. These claims have been recently evaluated in a meta-analysis (Sala & Gobet, 2016, Educational Research Review, 18, 46-57), which indicated a significant effect in favor of the groups playing chess. However, the meta-analysis also showed that most of the reviewed studies used a poor experimental design (in particular, they lacked an active control group). We ran two experiments that used a three-group design including both an active and a passive control group, with a focus on mathematical ability. In the first experiment (N = 233), a group of third and fourth graders was taught chess for 25 hours and tested on mathematical problem-solving tasks. Participants also filled in a questionnaire assessing their meta-cognitive ability for mathematics problems. The group playing chess was compared to an active control group (playing checkers) and a passive control group. The three groups showed no statistically significant difference in mathematical problem-solving or metacognitive abilities in the posttest. The second experiment (N = 52) broadly used the same design, but the Oriental game of Go replaced checkers in the active control group. While the chess-treated group and the passive control group slightly outperformed the active control group with mathematical problem solving, the differences were not statistically significant. No differences were found with respect to metacognitive ability. These results suggest that the effects (if any) of chess instruction, when rigorously tested, are modest and that such interventions should not replace the traditional curriculum in mathematics.

  14. A Study of Memory Effects in a Chess Database.

    PubMed

    Schaigorodsky, Ana L; Perotti, Juan I; Billoni, Orlando V

    2016-01-01

    A series of recent works studying a database of chronologically sorted chess games-containing 1.4 million games played by humans between 1998 and 2007- have shown that the popularity distribution of chess game-lines follows a Zipf's law, and that time series inferred from the sequences of those game-lines exhibit long-range memory effects. The presence of Zipf's law together with long-range memory effects was observed in several systems, however, the simultaneous emergence of these two phenomena were always studied separately up to now. In this work, by making use of a variant of the Yule-Simon preferential growth model, introduced by Cattuto et al., we provide an explanation for the simultaneous emergence of Zipf's law and long-range correlations memory effects in a chess database. We find that Cattuto's Model (CM) is able to reproduce both, Zipf's law and the long-range correlations, including size-dependent scaling of the Hurst exponent for the corresponding time series. CM allows an explanation for the simultaneous emergence of these two phenomena via a preferential growth dynamics, including a memory kernel, in the popularity distribution of chess game-lines. This mechanism results in an aging process in the chess game-line choice as the database grows. Moreover, we find burstiness in the activity of subsets of the most active players, although the aggregated activity of the pool of players displays inter-event times without burstiness. We show that CM is not able to produce time series with bursty behavior providing evidence that burstiness is not required for the explanation of the long-range correlation effects in the chess database. Our results provide further evidence favoring the hypothesis that long-range correlations effects are a consequence of the aging of game-lines and not burstiness, and shed light on the mechanism that operates in the simultaneous emergence of Zipf's law and long-range correlations in a community of chess players.

  15. A Study of Memory Effects in a Chess Database

    PubMed Central

    Schaigorodsky, Ana L.; Perotti, Juan I.; Billoni, Orlando V.

    2016-01-01

    A series of recent works studying a database of chronologically sorted chess games–containing 1.4 million games played by humans between 1998 and 2007– have shown that the popularity distribution of chess game-lines follows a Zipf’s law, and that time series inferred from the sequences of those game-lines exhibit long-range memory effects. The presence of Zipf’s law together with long-range memory effects was observed in several systems, however, the simultaneous emergence of these two phenomena were always studied separately up to now. In this work, by making use of a variant of the Yule-Simon preferential growth model, introduced by Cattuto et al., we provide an explanation for the simultaneous emergence of Zipf’s law and long-range correlations memory effects in a chess database. We find that Cattuto’s Model (CM) is able to reproduce both, Zipf’s law and the long-range correlations, including size-dependent scaling of the Hurst exponent for the corresponding time series. CM allows an explanation for the simultaneous emergence of these two phenomena via a preferential growth dynamics, including a memory kernel, in the popularity distribution of chess game-lines. This mechanism results in an aging process in the chess game-line choice as the database grows. Moreover, we find burstiness in the activity of subsets of the most active players, although the aggregated activity of the pool of players displays inter-event times without burstiness. We show that CM is not able to produce time series with bursty behavior providing evidence that burstiness is not required for the explanation of the long-range correlation effects in the chess database. Our results provide further evidence favoring the hypothesis that long-range correlations effects are a consequence of the aging of game-lines and not burstiness, and shed light on the mechanism that operates in the simultaneous emergence of Zipf’s law and long-range correlations in a community of chess players. PMID:28005922

  16. Mono-Energy Coronary Angiography with a Compact Synchrotron Source

    NASA Astrophysics Data System (ADS)

    Eggl, Elena; Mechlem, Korbinian; Braig, Eva; Kulpe, Stephanie; Dierolf, Martin; Günther, Benedikt; Achterhold, Klaus; Herzen, Julia; Gleich, Bernhard; Rummeny, Ernst; Noёl, Peter B.; Pfeiffer, Franz; Muenzel, Daniela

    2017-02-01

    X-ray coronary angiography is an invaluable tool for the diagnosis of coronary artery disease. However, the use of iodine-based contrast media can be contraindicated for patients who present with chronic renal insufficiency or with severe iodine allergy. These patients could benefit from a reduced contrast agent concentration, possibly achieved through application of a mono-energetic x-ray beam. While large-scale synchrotrons are impractical for daily clinical use, the technology of compact synchrotron sources strongly advanced during the last decade. Here we present a quantitative analysis of the benefits a compact synchrotron source can offer in coronary angiography. Simulated projection data from quasi-mono-energetic and conventional x-ray tube spectra is used for a CNR comparison. Results show that compact synchrotron spectra would allow for a significant reduction of contrast media. Experimentally, we demonstrate the feasibility of coronary angiography at the Munich Compact Light Source, the first commercial installation of a compact synchrotron source.

  17. Protein Data Bank depositions from synchrotron sources.

    PubMed

    Jiang, Jiansheng; Sweet, Robert M

    2004-07-01

    A survey and analysis of Protein Data Bank (PDB) depositions from international synchrotron radiation facilities, based on the latest released PDB entries, are reported. The results (http://asdp.bnl.gov/asda/Libraries/) show that worldwide, every year since 1999, more than 50% of the deposited X-ray structures have used synchrotron facilities, reaching 75% by 2003. In this web-based database, all PDB entries among individual synchrotron beamlines are archived, synchronized with the weekly PDB release. Statistics regarding the quality of experimental data and the refined model for all structures are presented, and these are analysed to reflect the impact of synchrotron sources. The results confirm the common impression that synchrotron sources extend the size of structures that can be solved with equivalent or better quality than home sources.

  18. Ultrahigh resolution protein crystallography: Concanavalin A to 0.94 Å and beyond

    NASA Astrophysics Data System (ADS)

    Deacon, A. M.; Gleichmann, T.; Harrop, S. J.; Helliwell, J. R.; Kalb Gilboa, A. J.; Yariv, J.

    1996-09-01

    Many years ago the idea of collecting voluminous quantities of weak reflection intensities from a protein crystal, at high resolution, was a particular challenge [J.R. Helliwell (1979) Daresbury Study Weekend DL/SCI R13, pp. 1-6]. The combination of insertion devices with very high x-ray fluxes at short x-ray wavelengths, sensitive CCD detectors, and freezing of crystals have provided the means to certainly match those best hopes. So much so that the data can best be described as ultrahigh resolution, at least as evidenced in our studies of the 25000 molecular weight plant protein concanavalin A. (The intrinsic property of this protein is to bind sugar molecules; it is implicated in cell-to-cell recognition processes and is widely used as a laboratory diagnostic tool.) At CHESS we have used a 0.9 Å wavelength beam on station A1, fed by a 24 pole multipole wiggler. Both an imaging plate system and the Princeton 1k CCD detector [M. Tate et al., J. Appl. Cryst. 28, 196 (1995)] have been used on this experimental setup to collect diffraction data sets from frozen concanavalin A crystals (saccharide-free crystal form). The rapid readout of the CCD was most convenient compared with the image plate and its associated scanning and erasing. Moreover the data processing results towards the edges of the detectors, 0.98 Å, show that the CCD is much better than the image plate at recording these weaker data (Rmerge(I) 13% versus 44%, respectively). The poor performance of the image plate with weak signals has of course been documented by the Daresbury detector group [R. Lewis, J. Synchrotron Radiation 1, 43 (1994)]. However, the aperture of the CCD used was limiting here. Very recently, in another run at CHESS with the CCD on A1, we have been able to record diffraction data to 0.94 Å by further offsetting the detector. We again found that the reflections are still strong at the edge. Clearly the use of even shorter wavelengths than 0.9 Å would be very useful in matching the solid angle of the diffraction pattern to the available detector aperture, for a reasonable crystal-to-detector distance. In addition, absorption errors in the data can be simultaneously removed by such a strategy. Indeed, finely focused x-ray beams of, say 0.5 Å wavelength, are especially well suited to high energy, low emittance synchrotron radition (SR) machines. Some initial tests carried out on CHESS station F2 with a 0.5 Å wavelength beam and the CCD detector show an improvement in the R-merge(I) to 2 Å resolution, in comparison to the data collected at 0.9 Å wavelength (i.e., 2.3% versus 3.0%). In conclusion, the diffraction resolution limit (0.94 Å) seen already in our concanavalin A studies can be further enhanced and is important for the most detailed molecular model refinement (and the testing of structure solving strategies), in conjunction with novel spectroscopic and theoretical studies. This paper builds upon the work of Deacon et al. [Rev. Sci. Instrum. 66, 1287 (1995)].

  19. Use of a Smartphone Recovery Tool for Latinos with Co-Occurring Alcohol and Other Drug Disorders and Mental Disorders.

    PubMed

    Muroff, Jordana; Robinson, Winslow; Chassler, Deborah; López, Luz M; Gaitan, Erika; Lundgren, Lena; Guauque, Claudia; Dargon-Hart, Susan; Stewart, Emily; Dejesus, Diliana; Johnson, Kimberly; Pe-Romashko, Klaren; Gustafson, David H

    2017-01-01

    Addressing alcohol and other drug disorders and other mental disorders among adult Hispanics/Latinos is of critical concern, as they are one of the fastest-growing ethnic groups with a disproportionate rate of disease, mental disorders, and poverty. Although improvement in outcomes is associated with sustained participation in ongoing treatment for co-occurring alcohol and other drug disorders/mental disorders, continuing care is rare for these chronic conditions, especially for Latinos with more limited access to culturally and linguistically competent services. The evidence-based smartphone recovery application Addiction-Comprehensive Health Enhancement Support System (A-CHESS) was translated and adapted for Spanish-speaking Latinos with alcohol and other drug disorders/mental disorders, thus developing CASA-CHESS to address a high level of need for services, high rates of relapse, and lack of existing culturally competent services for Latinos. Of the 79 Latino clients who completed residential treatment and received a smartphone equipped with CASA-CHESS, 26.6% discontinued using CASA-CHESS and 73.4% remained active for four or more months. CASA-CHESS usage was sustained over the four months across all three tenets of self-determination theory (competence, relatedness, and autonomy), with the most commonly utilized services being relevant to relatedness (e.g., messaging, discussion boards). CASA-CHESS clients demonstrated a similar pattern of usage to A-CHESS clients. Findings illustrate that Spanish-speaking Latinos with alcohol and other drug disorders/mental disorders will use a smartphone application to assist with their recovery, continuing their access to resources, case management, and quality information after leaving residential treatment. Consistent with previous findings, our results also emphasize the importance of social support during the four months post-discharge. Such evidence-based, theory-driven digital interventions may extend access to culturally and linguistically competent services.

  20. Expert vs. novice differences in the detection of relevant information during a chess game: evidence from eye movements

    PubMed Central

    Sheridan, Heather; Reingold, Eyal M.

    2014-01-01

    The present study explored the ability of expert and novice chess players to rapidly distinguish between regions of a chessboard that were relevant to the best move on the board, and regions of the board that were irrelevant. Accordingly, we monitored the eye movements of expert and novice chess players, while they selected white's best move for a variety of chess problems. To manipulate relevancy, we constructed two different versions of each chess problem in the experiment, and we counterbalanced these versions across participants. These two versions of each problem were identical except that a single piece was changed from a bishop to a knight. This subtle change reversed the relevancy map of the board, such that regions that were relevant in one version of the board were now irrelevant (and vice versa). Using this paradigm, we demonstrated that both the experts and novices spent more time fixating the relevant relative to the irrelevant regions of the board. However, the experts were faster at detecting relevant information than the novices, as shown by the finding that experts (but not novices) were able to distinguish between relevant and irrelevant information during the early part of the trial. These findings further demonstrate the domain-related perceptual processing advantage of chess experts, using an experimental paradigm that allowed us to manipulate relevancy under tightly controlled conditions. PMID:25202298

  1. Expert vs. novice differences in the detection of relevant information during a chess game: evidence from eye movements.

    PubMed

    Sheridan, Heather; Reingold, Eyal M

    2014-01-01

    The present study explored the ability of expert and novice chess players to rapidly distinguish between regions of a chessboard that were relevant to the best move on the board, and regions of the board that were irrelevant. Accordingly, we monitored the eye movements of expert and novice chess players, while they selected white's best move for a variety of chess problems. To manipulate relevancy, we constructed two different versions of each chess problem in the experiment, and we counterbalanced these versions across participants. These two versions of each problem were identical except that a single piece was changed from a bishop to a knight. This subtle change reversed the relevancy map of the board, such that regions that were relevant in one version of the board were now irrelevant (and vice versa). Using this paradigm, we demonstrated that both the experts and novices spent more time fixating the relevant relative to the irrelevant regions of the board. However, the experts were faster at detecting relevant information than the novices, as shown by the finding that experts (but not novices) were able to distinguish between relevant and irrelevant information during the early part of the trial. These findings further demonstrate the domain-related perceptual processing advantage of chess experts, using an experimental paradigm that allowed us to manipulate relevancy under tightly controlled conditions.

  2. Spatial part-set cuing facilitation.

    PubMed

    Kelley, Matthew R; Parasiuk, Yuri; Salgado-Benz, Jennifer; Crocco, Megan

    2016-07-01

    Cole, Reysen, and Kelley [2013. Part-set cuing facilitation for spatial information. Journal of Experimental Psychology: Learning, Memory, & Cognition, 39, 1615-1620] reported robust part-set cuing facilitation for spatial information using snap circuits (a colour-coded electronics kit designed for children to create rudimentary circuit boards). In contrast, Drinkwater, Dagnall, and Parker [2006. Effects of part-set cuing on experienced and novice chess players' reconstruction of a typical chess midgame position. Perceptual and Motor Skills, 102(3), 645-653] and Watkins, Schwartz, and Lane [1984. Does part-set cuing test for memory organization? Evidence from reconstructions of chess positions. Canadian Journal of Psychology/Revue Canadienne de Psychologie, 38(3), 498-503] showed no influence of part-set cuing for spatial information when using chess boards. One key difference between the two procedures was that the snap circuit stimuli were explicitly connected to one another, whereas chess pieces were not. Two experiments examined the effects of connection type (connected vs. unconnected) and cue type (cued vs. uncued) on memory for spatial information. Using chess boards (Experiment 1) and snap circuits (Experiment 2), part-set cuing facilitation only occurred when the stimuli were explicitly connected; there was no influence of cuing with unconnected stimuli. These results are potentially consistent with the retrieval strategy disruption hypothesis, as well as the two- and three-mechanism accounts of part-set cuing.

  3. Structure constrained by metadata in networks of chess players.

    PubMed

    Almeira, Nahuel; Schaigorodsky, Ana L; Perotti, Juan I; Billoni, Orlando V

    2017-11-09

    Chess is an emblematic sport that stands out because of its age, popularity and complexity. It has served to study human behavior from the perspective of a wide number of disciplines, from cognitive skills such as memory and learning, to aspects like innovation and decision-making. Given that an extensive documentation of chess games played throughout history is available, it is possible to perform detailed and statistically significant studies about this sport. Here we use one of the most extensive chess databases in the world to construct two networks of chess players. One of the networks includes games that were played over-the-board and the other contains games played on the Internet. We study the main topological characteristics of the networks, such as degree distribution and correlations, transitivity and community structure. We complement the structural analysis by incorporating players' level of play as node metadata. Although both networks are topologically different, we show that in both cases players gather in communities according to their expertise and that an emergent rich-club structure, composed by the top-rated players, is also present.

  4. Efficient Computation of Sparse Matrix Functions for Large-Scale Electronic Structure Calculations: The CheSS Library.

    PubMed

    Mohr, Stephan; Dawson, William; Wagner, Michael; Caliste, Damien; Nakajima, Takahito; Genovese, Luigi

    2017-10-10

    We present CheSS, the "Chebyshev Sparse Solvers" library, which has been designed to solve typical problems arising in large-scale electronic structure calculations using localized basis sets. The library is based on a flexible and efficient expansion in terms of Chebyshev polynomials and presently features the calculation of the density matrix, the calculation of matrix powers for arbitrary powers, and the extraction of eigenvalues in a selected interval. CheSS is able to exploit the sparsity of the matrices and scales linearly with respect to the number of nonzero entries, making it well-suited for large-scale calculations. The approach is particularly adapted for setups leading to small spectral widths of the involved matrices and outperforms alternative methods in this regime. By coupling CheSS to the DFT code BigDFT, we show that such a favorable setup is indeed possible in practice. In addition, the approach based on Chebyshev polynomials can be massively parallelized, and CheSS exhibits excellent scaling up to thousands of cores even for relatively small matrix sizes.

  5. The effects of time pressure on chess skill: an investigation into fast and slow processes underlying expert performance.

    PubMed

    van Harreveld, Frenk; Wagenmakers, Eric-Jan; van der Maas, Han L J

    2007-09-01

    The ability to play chess is generally assumed to depend on two types of processes: slow processes such as search, and fast processes such as pattern recognition. It has been argued that an increase in time pressure during a game selectively hinders the ability to engage in slow processes. Here we study the effect of time pressure on expert chess performance in order to test the hypothesis that compared to weak players, strong players depend relatively heavily on fast processes. In the first study we examine the performance of players of various strengths at an online chess server, for games played under different time controls. In a second study we examine the effect of time controls on performance in world championship matches. Both studies consistently show that skill differences between players become less predictive of the game outcome as the time controls are tightened. This result indicates that slow processes are at least as important for strong players as they are for weak players. Our findings pose a challenge for current theorizing in the field of expertise and chess.

  6. Multiple Wheel Throwing: And Chess Sets.

    ERIC Educational Resources Information Center

    Sapiro, Maurice

    1978-01-01

    A chess set project is suggested to teach multiple throwing, the creation on a potter's wheel of several pieces of similar configuration. Processes and finished sets are illustrated with photographs. (SJL)

  7. A resolution expressing support for the designation of Saint Louis, Missouri, as the "National Chess Capital" of the United States to enhance awareness of the educational benefits of chess and to encourage schools and community centers to engage in chess programs to promote problem-solving, critical thinking, spatial awareness, and goal setting.

    THOMAS, 113th Congress

    Sen. McCaskill, Claire [D-MO

    2013-04-18

    Senate - 05/05/2014 Resolution agreed to in Senate without amendment and with a preamble by Unanimous Consent. (All Actions) Tracker: This bill has the status Agreed to in SenateHere are the steps for Status of Legislation:

  8. Effects of automated smartphone mobile recovery support and telephone continuing care in the treatment of alcohol use disorder: study protocol for a randomized controlled trial.

    PubMed

    McKay, James R; Gustafson, David H; Ivey, Megan; McTavish, Fiona; Pe-Romashko, Klaren; Curtis, Brenda; Oslin, David A; Polsky, Daniel; Quanbeck, Andrew; Lynch, Kevin G

    2018-01-30

    New smartphone communication technology provides a novel way to provide personalized continuing care support following alcohol treatment. One such system is the Addiction version of the Comprehensive Health Enhancement Support System (A-CHESS), which provides a range of automated functions that support patients. A-CHESS improved drinking outcomes over standard continuing care when provided to patients leaving inpatient treatment. Effective continuing care can also be delivered via telephone calls with a counselor. Telephone Monitoring and Counseling (TMC) has demonstrated efficacy in two randomized trials with alcohol-dependent patients. A-CHESS and TMC have complementary strengths. A-CHESS provides automated 24/7 recovery support services and frequent assessment of symptoms and status, but does not involve regular contact with a counselor. TMC provides regular and sustained contact with the same counselor, but no ongoing support between calls. The future of continuing care for alcohol use disorders is likely to involve automated mobile technology and counselor contact, but little is known about how best to integrate these services. To address this question, the study will feature a 2 × 2 design (A-CHESS for 12 months [yes/no] × TMC for 12 months [yes/no]), in which 280 alcohol-dependent patients in intensive outpatient programs (IOPs) will be randomized to one of the four conditions and followed for 18 months. We will determine whether adding TMC to A-CHESS produces fewer heavy drinking days than TMC or A-CHESS alone and test for TMC and A-CHESS main effects. We will determine the costs of each of the four conditions and the incremental cost-effectiveness of the three active conditions. Analyses will also examine secondary outcomes, including a biological measure of alcohol use, and hypothesized moderation and mediation effects. The results of the study will yield important information on improving patient alcohol use outcomes by integrating mobile automated recovery support and counselor contact. ClinicalTrials.gov, NCT02681406 . Registered on 2 September 2016.

  9. Treatment seeking as a mechanism of change in a randomized controlled trial of a mobile health intervention to support recovery from alcohol use disorders.

    PubMed

    Glass, Joseph E; McKay, James R; Gustafson, David H; Kornfield, Rachel; Rathouz, Paul J; McTavish, Fiona M; Atwood, Amy K; Isham, Andrew; Quanbeck, Andrew; Shah, Dhavan

    2017-06-01

    We estimated the efficacy of the Addiction-Comprehensive Health Enhancement Support System (A-CHESS) in increasing the use of services for addiction and examined the extent to which this use of services mediated the effects of A-CHESS on risky drinking days and abstinence from drinking. We conducted secondary data analyses of the A-CHESS randomized controlled trial. Recruitment occurred in five residential treatment programs operated by two addiction treatment organizations. Participants were 349 adults with alcohol use disorders recruited two weeks before discharge from residential treatment. We provided intervention arm participants with a smartphone, the A-CHESS application, and an 8-month service plan. Control arm participants received treatment as usual. Telephone interviews at 4, 8, and 12-month follow-ups assessed past-month risky drinking days, past-month abstinence, and post-discharge service utilization (past-month outpatient addiction treatment and past-week mutual help including Alcoholics Anonymous and Narcotics Anonymous). Using mixed effects latent variable models, we estimated the indirect effects of A-CHESS on drinking outcomes, as mediated by post-discharge service utilization. Approximately 50.5% of participants reported outpatient addiction treatment and 75.5% reported mutual help at any follow-up interview in the year following randomization. Assignment to the A-CHESS intervention was associated with an increased odds of outpatient addiction treatment across follow-ups, but not mutual help. This use of outpatient addiction treatment mediated the effect of A-CHESS on risky drinking days, but not abstinence. The effect of A-CHESS through outpatient addiction treatment appeared to reduce the expected number of risky drinking days across follow-ups by 11%. The mobile health (mHealth) intervention promoted the use of outpatient addiction treatment, which appeared to contribute to its efficacy in reducing risky drinking. Future research should investigate how mHealth interventions could link patients to needed treatment services and promote the sustained use of these services. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. The uses of synchrotron radiation sources for elemental and chemical microanalysis

    USGS Publications Warehouse

    Chen, J.R.; Chao, E.C.T.; Minkin, J.A.; Back, J.M.; Jones, K.W.; Rivers, M.L.; Sutton, S.R.

    1990-01-01

    Synchrotron radiation sources offer important features for the analysis of a material. Among these features is the ability to determine both the elemental composition of the material and the chemical state of its elements. For microscopic analysis synchrotron X-ray fluorescence (SXRF) microprobes now offer spatial resolutions of 10 ??m with minimum detection limits in the 1-10 ppm range depending on the nature of the sample and the synchrotron source used. This paper describes the properties of synchrotron radiation and their importance for elemental analysis, existing synchrotron facilities and those under construction that are optimum for SXRF microanalysis, and a number of applications including the high energy excitation of the K lines of heavy elements, microtomography, and XANES and EXAFS spectroscopies. ?? 1990.

  11. 'Checkmating HIV&AIDS': Using chess to break the silence in the classroom.

    PubMed

    Esau, Omar

    2012-12-01

    In this article, I give an account of my 'Checkmating HIV&AIDS' action research project, which was an attempt to break the 'culture of silence' concerning HIV&AIDS and sex and sexuality in my classroom. In this project, I focused specifically on one code of sport, namely chess, and I point out and discuss the potential of using chess as an educational tool in addressing HIV&AIDS. It was found that learners enjoy playing chess and that it can be used in the Life Orientation classroom to promote HIV&AIDS awareness. This type of alternative awareness is relevant as learners in most schools were becoming fatigued by HIV&AIDS information overload. The project portrays the role of the teacher as a researcher and critical change agent in an HIV&AIDS-challenged society.

  12. Perceptron Genetic to Recognize Openning Strategy Ruy Lopez

    NASA Astrophysics Data System (ADS)

    Azmi, Zulfian; Mawengkang, Herman

    2018-01-01

    The application of Perceptron method is not effective for coding on hardware based systems because it is not real time learning. With Genetic algorithm approach in calculating and searching the best weight (fitness value) system will do learning only one iteration. And the results of this analysis were tested in the case of the introduction of the opening pattern of chess Ruy Lopez. The Analysis with Perceptron Model with Algorithm Approach Genetics from group Artificial Neural Network for open Ruy Lopez. The data is processed with base open chess, with step eight a position white Pion from end open chess. Using perceptron method have many input and one output process many weight and refraction until output equal goal. Data trained and test with software Matlab and system can recognize the chess opening Ruy Lopez or Not open Ruy Lopez with Real time.

  13. Fat suppression with short inversion time inversion-recovery and chemical-shift selective saturation: a dual STIR-CHESS combination prepulse for turbo spin echo pulse sequences.

    PubMed

    Tanabe, Koji; Nishikawa, Keiichi; Sano, Tsukasa; Sakai, Osamu; Jara, Hernán

    2010-05-01

    To test a newly developed fat suppression magnetic resonance imaging (MRI) prepulse that synergistically uses the principles of fat suppression via inversion recovery (STIR) and spectral fat saturation (CHESS), relative to pure CHESS and STIR. This new technique is termed dual fat suppression (Dual-FS). To determine if Dual-FS could be chemically specific for fat, the phantom consisted of the fat-mimicking NiCl(2) aqueous solution, porcine fat, porcine muscle, and water was imaged with the three fat-suppression techniques. For Dual-FS and STIR, several inversion times were used. Signal intensities of each image obtained with each technique were compared. To determine if Dual-FS could be robust to magnetic field inhomogeneities, the phantom consisting of different NiCl(2) aqueous solutions, porcine fat, porcine muscle, and water was imaged with Dual-FS and CHESS at the several off-resonance frequencies. To compare fat suppression efficiency in vivo, 10 volunteer subjects were also imaged with the three fat-suppression techniques. Dual-FS could suppress fat sufficiently within the inversion time of 110-140 msec, thus enabling differentiation between fat and fat-mimicking aqueous structures. Dual-FS was as robust to magnetic field inhomogeneities as STIR and less vulnerable than CHESS. The same results for fat suppression were obtained in volunteers. The Dual-FS-STIR-CHESS is an alternative and promising fat suppression technique for turbo spin echo MRI. Copyright 2010 Wiley-Liss, Inc.

  14. Chemical Entity Semantic Specification: Knowledge representation for efficient semantic cheminformatics and facile data integration

    PubMed Central

    2011-01-01

    Background Over the past several centuries, chemistry has permeated virtually every facet of human lifestyle, enriching fields as diverse as medicine, agriculture, manufacturing, warfare, and electronics, among numerous others. Unfortunately, application-specific, incompatible chemical information formats and representation strategies have emerged as a result of such diverse adoption of chemistry. Although a number of efforts have been dedicated to unifying the computational representation of chemical information, disparities between the various chemical databases still persist and stand in the way of cross-domain, interdisciplinary investigations. Through a common syntax and formal semantics, Semantic Web technology offers the ability to accurately represent, integrate, reason about and query across diverse chemical information. Results Here we specify and implement the Chemical Entity Semantic Specification (CHESS) for the representation of polyatomic chemical entities, their substructures, bonds, atoms, and reactions using Semantic Web technologies. CHESS provides means to capture aspects of their corresponding chemical descriptors, connectivity, functional composition, and geometric structure while specifying mechanisms for data provenance. We demonstrate that using our readily extensible specification, it is possible to efficiently integrate multiple disparate chemical data sources, while retaining appropriate correspondence of chemical descriptors, with very little additional effort. We demonstrate the impact of some of our representational decisions on the performance of chemically-aware knowledgebase searching and rudimentary reaction candidate selection. Finally, we provide access to the tools necessary to carry out chemical entity encoding in CHESS, along with a sample knowledgebase. Conclusions By harnessing the power of Semantic Web technologies with CHESS, it is possible to provide a means of facile cross-domain chemical knowledge integration with full preservation of data correspondence and provenance. Our representation builds on existing cheminformatics technologies and, by the virtue of RDF specification, remains flexible and amenable to application- and domain-specific annotations without compromising chemical data integration. We conclude that the adoption of a consistent and semantically-enabled chemical specification is imperative for surviving the coming chemical data deluge and supporting systems science research. PMID:21595881

  15. Chemical Entity Semantic Specification: Knowledge representation for efficient semantic cheminformatics and facile data integration.

    PubMed

    Chepelev, Leonid L; Dumontier, Michel

    2011-05-19

    Over the past several centuries, chemistry has permeated virtually every facet of human lifestyle, enriching fields as diverse as medicine, agriculture, manufacturing, warfare, and electronics, among numerous others. Unfortunately, application-specific, incompatible chemical information formats and representation strategies have emerged as a result of such diverse adoption of chemistry. Although a number of efforts have been dedicated to unifying the computational representation of chemical information, disparities between the various chemical databases still persist and stand in the way of cross-domain, interdisciplinary investigations. Through a common syntax and formal semantics, Semantic Web technology offers the ability to accurately represent, integrate, reason about and query across diverse chemical information. Here we specify and implement the Chemical Entity Semantic Specification (CHESS) for the representation of polyatomic chemical entities, their substructures, bonds, atoms, and reactions using Semantic Web technologies. CHESS provides means to capture aspects of their corresponding chemical descriptors, connectivity, functional composition, and geometric structure while specifying mechanisms for data provenance. We demonstrate that using our readily extensible specification, it is possible to efficiently integrate multiple disparate chemical data sources, while retaining appropriate correspondence of chemical descriptors, with very little additional effort. We demonstrate the impact of some of our representational decisions on the performance of chemically-aware knowledgebase searching and rudimentary reaction candidate selection. Finally, we provide access to the tools necessary to carry out chemical entity encoding in CHESS, along with a sample knowledgebase. By harnessing the power of Semantic Web technologies with CHESS, it is possible to provide a means of facile cross-domain chemical knowledge integration with full preservation of data correspondence and provenance. Our representation builds on existing cheminformatics technologies and, by the virtue of RDF specification, remains flexible and amenable to application- and domain-specific annotations without compromising chemical data integration. We conclude that the adoption of a consistent and semantically-enabled chemical specification is imperative for surviving the coming chemical data deluge and supporting systems science research.

  16. Synchrotron light sources in developing countries

    DOE PAGES

    Mtingwa, Sekazi K.; Winick, Herman

    2018-03-21

    Here, we discuss the role that synchrotron light sources, such as SESAME, could play in improving the socioeconomic conditions in developing countries. After providing a brief description of a synchrotron light source, we discuss the important role that they played in the development of several economically emerging countries. Then we describe the state of synchrotron science in South Africa and that country’s leadership role in founding the African Light Source initiative. Next, we highlight a new initiative called Lightsources for Africa, the Americas & Middle East Project, which is a global initiative led by the International Union of Pure andmore » Applied Physics and the International Union of Crystallography, with initial funding provided by the International Council for Science. Finally, we comment on a new technology called the multibend achromat that has launched a new paradigm for the design of synchrotron light sources that should be attractive for construction in developing countries.« less

  17. Synchrotron light sources in developing countries

    NASA Astrophysics Data System (ADS)

    Mtingwa, Sekazi K.; Winick, Herman

    2018-03-01

    We discuss the role that synchrotron light sources, such as SESAME, could play in improving the socioeconomic conditions in developing countries. After providing a brief description of a synchrotron light source, we discuss the important role that they played in the development of several economically emerging countries. Then we describe the state of synchrotron science in South Africa and that country’s leadership role in founding the African Light Source initiative. Next, we highlight a new initiative called Lightsources for Africa, the Americas & Middle East Project, which is a global initiative led by the International Union of Pure and Applied Physics and the International Union of Crystallography, with initial funding provided by the International Council for Science. Finally, we comment on a new technology called the multibend achromat that has launched a new paradigm for the design of synchrotron light sources that should be attractive for construction in developing countries.

  18. Atomic physics research with second and third generation synchrotron light sources

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Johnson, B.M.

    1990-10-01

    This contribution to these proceedings is intended to provide an introduction and overview for other contributions on atomic (and related) physics research at existing and planned synchrotron light sources. The emphasis will be on research accomplishments and future opportunities, but a comparison will be given of operating characteristics for first, second, and third generation machines. First generation light sources were built to do research with the primary electron and positron beams, rather than with the synchrotron radiation itself. Second generation machines were specifically designed to be dedicated synchrotron-radiation facilities, with an emphasis on the use of bending-magnet radiation. The newmore » third generation light sources are being designed to optimize radiation from insertion devices, such as undulators and wigglers. Each generation of synchrotron light source offers useful capabilities for forefront research in atomic physics and many other disciplines. 27 refs., 1 fig., 3 tabs.« less

  19. Synchrotron light sources in developing countries

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mtingwa, Sekazi K.; Winick, Herman

    Here, we discuss the role that synchrotron light sources, such as SESAME, could play in improving the socioeconomic conditions in developing countries. After providing a brief description of a synchrotron light source, we discuss the important role that they played in the development of several economically emerging countries. Then we describe the state of synchrotron science in South Africa and that country’s leadership role in founding the African Light Source initiative. Next, we highlight a new initiative called Lightsources for Africa, the Americas & Middle East Project, which is a global initiative led by the International Union of Pure andmore » Applied Physics and the International Union of Crystallography, with initial funding provided by the International Council for Science. Finally, we comment on a new technology called the multibend achromat that has launched a new paradigm for the design of synchrotron light sources that should be attractive for construction in developing countries.« less

  20. Chamitoff plays chess in the Node 2 during Expedition 17

    NASA Image and Video Library

    2008-07-19

    ISS017-E-011577 (19 July 2008) --- NASA astronaut Greg Chamitoff, Expedition 17 flight engineer, ponders his next move as he plays a game of chess in the Harmony node of the International Space Station.

  1. Impact of synchrotron radiation on macromolecular crystallography: a personal view

    PubMed Central

    Dauter, Zbigniew; Jaskolski, Mariusz; Wlodawer, Alexander

    2010-01-01

    The introduction of synchrotron radiation sources almost four decades ago has led to a revolutionary change in the way that diffraction data from macromolecular crystals are being collected. Here a brief history of the development of methodologies that took advantage of the availability of synchrotron sources are presented, and some personal experiences with the utilization of synchrotrons in the early days are recalled. PMID:20567074

  2. Female Chess Players Outperform Expectations When Playing Men.

    PubMed

    Stafford, Tom

    2018-03-01

    Stereotype threat has been offered as a potential explanation of differential performance between men and women in some cognitive domains. Questions remain about the reliability and generality of the phenomenon. Previous studies have found that stereotype threat is activated in female chess players when they are matched against male players. I used data from over 5.5 million games of international tournament chess and found no evidence of a stereotype-threat effect. In fact, female players outperform expectations when playing men. Further analysis showed no influence of degree of challenge, player age, nor prevalence of female role models in national chess leagues on differences in performance when women play men versus when they play women. Though this analysis contradicts one specific mechanism of influence of gender stereotypes, the persistent differences between male and female players suggest that systematic factors do exist and remain to be uncovered.

  3. The benefits of chess for the intellectual and social-emotional enrichment in schoolchildren.

    PubMed

    Aciego, Ramón; García, Lorena; Betancort, Moisés

    2012-07-01

    This paper examines the benefits of regularly playing chess for the intellectual and social-emotional enrichment of a group of 170 schoolchildren from 6-16 years old. It is based on a quasi-experimental design, where the independent variable was the extracurricular activity of chess (n = 170) versus extracurricular activities of soccer or basketball (n = 60). The dependent variable was intellectual and socio-affective competence, which was measured by an IQ test (WISC-R), a self-report test (TAMAI) and a hetero-report questionnaire (teacher-tutor's criterion) applied at the beginning and the end of the academic year. In contrast to the comparison group, it was found that chess improves cognitive abilities, coping and problem-solving capacity, and even socioaffective development of children and adolescents who practice it. The results are modulated, particularly in the area socioaffective, by the personal profile of students who choose practice this activity.

  4. Effects of weather anomalies on the intellectual performance: Chess mistakes of the world top-ranked players

    NASA Astrophysics Data System (ADS)

    Mika, J.; Verőci, Zs.; Fülöp, A.; Hirsch, T.; Dúll, A.

    2009-04-01

    Weather disturbances like fronts, influence human biorhythm, our biological balance becomes manipulated, and adaptation mechanisms are impaired. Our working hypothesis is that even the best chess players of the world are not exceptions from this rule. As their movements on the chess board, as well as the best possible ones, if they missed to make, are already assessed by computers objectively, we can use this game as a model of intellectual performance. By the date of the Abstract edition, 580 wrong chess moves were selected with the threshold of over 1/3 peasant to be lost. I.e. this is the minimum difference between the assessment of the positions after the best possible and the really performed move. (Obviously, all moves both sides in ca. the same number of games were checked, i.e. over 35,000 moves were assessed.) For assessing the moves, the most popular database is MegaDatabase 2006 (ChessBase- Hamburg), Chess Informant Expert from Chess Informant Beograd and the program ChessBase 9.0 together with the engines Fritz 10, Rybka 2.3, Junior 10. First of all the World Chess Champions, Karpov, Kasparov, Kramnik and Anand were examined played in the traditional big chess tournaments, category 19th and more (average rating more the 2701 Elo-points). We further selected the games by the top-ranked players of the world between 2005 and 2008. This selection is explained by the likely fact that they make the less wrong moves for simply the lack of chess understanding, moreover, as full professionals, they allow the minimum of non-weather disturbing circumstances (e.g. imperfect sleeping before the game, etc.). Their moves were selected as (i) very wrong move with more than 3.0 differences, (i.e. unforced loss of a knight, or a bishop, (ii) very weak move with an assessment of 1.0-3.0, (i.e. unforced loss between one peasant and one bishop/knight) and (iii) weak move with less than 1.0 assessment of the passed chance, or unforced loss of less than one peasant. These new data on mental behavior are statistically compared to a common set of diurnal meteorological parameters, including various near-surface and lower troposphere temperature values, sea-level pressures, relative topographies, precipitation amount and existence (duration) and wind speed. The data and the aerologic fields are retrieved from the ECMWF ERA-40 (until 2002) and ECMWF operational analysis (after 2002) for the date and site of the individual mistakes. According to our preliminary results, the wrong moves fall to the lower or higher than average parts of the diurnal mean temperature distribution. Even if we should be careful because of the well known bi-modal distribution of the temperature (if not performing any seasonal correction), but, even after considering these differences the best players make more frequent mistakes in case of higher or lower than normal temperature situations. Another preliminary experience is that decreasing tendency of the RT850/500 hPa relative topography also indicates increase of wrong and very wrong moves. After performing this analysis, the result will be compared to the better known empirical paradigms of medical meteorology and experimental psychology.

  5. CHESS improves cancer caregivers' burden and mood: results of an eHealth RCT.

    PubMed

    DuBenske, Lori L; Gustafson, David H; Namkoong, Kang; Hawkins, Robert P; Atwood, Amy K; Brown, Roger L; Chih, Ming-Yuan; McTavish, Fiona; Carmack, Cindy L; Buss, Mary K; Govindan, Ramaswamy; Cleary, James F

    2014-10-01

    Informal caregivers (family and friends) of people with cancer are often unprepared for their caregiving role, leading to increased burden or distress. Comprehensive Health Enhancement Support System (CHESS) is a Web-based lung cancer information, communication, and coaching system for caregivers. This randomized trial reports the impact on caregiver burden, disruptiveness, and mood of providing caregivers access to CHESS versus the Internet with a list of recommended lung cancer websites. A total of 285 informal caregivers of patients with advanced nonsmall cell lung cancer were randomly assigned to a comparison group that received Internet or a treatment group that received Internet and CHESS. Caregivers were provided a computer and Internet service if needed. Written surveys were completed at pretest and during the intervention period bimonthly for up to 24 months. Analyses of covariance (ANCOVAs) compared the intervention's effect on caregivers' disruptiveness and burden (CQOLI-C), and negative mood (combined Anxiety, Depression, and Anger scales of the POMS) at 6 months, controlling for blocking variables (site, caregiver's race, and relationship to patient) and the given outcome at pretest. Caregivers randomized to CHESS reported lower burden, t(84) = 2.36, p = .021, d = .39, and negative mood, t(86) = 2.82, p = .006, d = .44, than those in the Internet group. The effect on disruptiveness was not significant. Although caring for someone with a terminal illness will always exact a toll on caregivers, eHealth interventions like CHESS may improve caregivers' understanding and coping skills and, as a result, ease their burden and mood.

  6. CHESS Improves Cancer Caregivers’ Burden and Mood: Results of an eHealth RCT

    PubMed Central

    DuBenske, Lori L.; Gustafson, David H.; Namkoong, Kang; Hawkins, Robert P.; Atwood, Amy K.; Brown, Roger L.; Chih, Ming-Yuan; McTavish, Fiona; Carmack, Cindy L.; Buss, Mary K.; Govindan, Ramaswamy; Cleary, James F.

    2014-01-01

    Objective Informal caregivers (family and friends) of people with cancer are often unprepared for their caregiving role, leading to increased burden or distress. CHESS (Comprehensive Health Enhancement Support System) is a web-based lung cancer information, communication and coaching system for caregivers. This randomized trial reports the impact on caregiver burden, disruptiveness and mood of providing caregivers access to CHESS versus the Internet with a list of recommended lung cancer websites. Methods 285 informal caregivers of patients with advanced non-small cell lung cancer were randomly assigned to a comparison group that received Internet or a treatment group that received Internet and CHESS. Caregivers were provided a computer and Internet service if needed. Written surveys were completed at pretest and during the intervention period bimonthly for up to 24 months. ANCOVA analyses compared the intervention’s effect on caregivers’ disruptiveness and burden (CQOLI-C), and negative mood (combined Anxiety, Depression, and Anger scales of the POMS) at six months, controlling for blocking variables (site, caregiver’s race, and relationship to patient) and the given outcome at pretest. Results Caregivers randomized to CHESS reported lower burden [t (84) = 2.36, p = .021, d= .39] and negative mood [t (86) = 2.82, p = .006, d= .44] than those in the Internet group. The effect on disruptiveness was not significant. Conclusions Although caring for someone with a terminal illness will always exact a toll on caregivers, eHealth interventions like CHESS may improve caregivers’ understanding and coping skills and, as a result, ease their burden and mood. PMID:24245838

  7. Methylphenidate, modafinil, and caffeine for cognitive enhancement in chess: A double-blind, randomised controlled trial.

    PubMed

    Franke, Andreas G; Gränsmark, Patrik; Agricola, Alexandra; Schühle, Kai; Rommel, Thilo; Sebastian, Alexandra; Balló, Harald E; Gorbulev, Stanislav; Gerdes, Christer; Frank, Björn; Ruckes, Christian; Tüscher, Oliver; Lieb, Klaus

    2017-03-01

    Stimulants and caffeine have been proposed for cognitive enhancement by healthy subjects. This study investigated whether performance in chess - a competitive mind game requiring highly complex cognitive skills - can be enhanced by methylphenidate, modafinil or caffeine. In a phase IV, randomized, double-blind, placebo-controlled trial, 39 male chess players received 2×200mg modafinil, 2×20mg methylphenidate, and 2×200mg caffeine or placebo in a 4×4 crossover design. They played twenty 15-minute games during two sessions against a chess program (Fritz 12; adapted to players' strength) and completed several neuropsychological tests. Marked substance effects were observed since all three substances significantly increased average reflection time per game compared to placebo resulting in a significantly increased number of games lost on time with all three treatments. Treatment effects on chess performance were not seen if all games (n=3059) were analysed. Only when controlling for game duration as well as when excluding those games lost on time, both modafinil and methylphenidate enhanced chess performance as demonstrated by significantly higher scores in the remaining 2876 games compared to placebo. In conjunction with results from neuropsychological testing we conclude that modifying effects of stimulants on complex cognitive tasks may in particular result from more reflective decision making processes. When not under time pressure, such effects may result in enhanced performance. Yet, under time constraints more reflective decision making may not improve or even have detrimental effects on complex task performance. Copyright © 2017 Elsevier B.V. and ECNP. All rights reserved.

  8. Memory for Chess Positions: Resistance to Interference

    ERIC Educational Resources Information Center

    Charness, Neil

    1976-01-01

    An information processing model, Memory-Aided Pattern Perceiver (MAPP), that simulates the recall of briefly presented chess positions, was subjected to a test of its assumption that such positions are encoded and stored as chunks in short-term memory. (Editor)

  9. Updates on the African Synchrotron Light Source (AfLS) Project

    NASA Astrophysics Data System (ADS)

    Dobbins, Tabbetha; Mtingwa, Sekazi; Wague, Ahmadou; Connell, Simon; Masara, Brian; Ntsoane, Tshepo; Norris, Lawrence; Winick, Herman; Evans-Lutterodt, Kenneth; Hussein, Tarek; Maresha, Feene; McLaughlin, Krystle; Oladijo, Philip; Du Plessis, Esna; Murenzi, Romain; Reed, Kennedy; Sette, Francesco; Werin, Sverker; Dorfan, Jonathan; Yousef, Mohammad

    Africa is the only habitable continent without a synchrotron light source. A full steering committee was elected at the African Light Source (AfLS) conference on November 16-20, 2015 at the European Synchrotron Radiation Facility (ESRF) in Grenoble, France. The conference brought together African scientists, policy makers, and stakeholders to discuss a synchrotron light source in Africa. Firm outcomes of the Conference were a set of resolutions and a roadmap. Additionally, a collaborative proposal to promote Advanced Light Sources and crystallographic sciences in targeted regions of the world was submitted by the International Union of Pure and Applied Physics (IUPAP) and the International Union of Crystallography (IUCr) to the International Council for Science (ICSU). www.africanlightsource.org.

  10. Some aspects of cosmic synchrotron sources

    NASA Technical Reports Server (NTRS)

    Epstein, R. I.

    1973-01-01

    Synchrotron emission is considered from individual particles which have small pitch angles and the general properties of synchrotron sources which mainly contain such particles, as well as the emissivities and degrees of circular polarization for specific source distributions. The limitation of synchrotron source models for optical pulsars and compact extragalactic objects are discussed, and it is shown that several existing models for the pulsar NP 0532 are inconsistent with the measured time variations and polarizations of the optical emission. Discussion is made also of whether the low frequency falloffs in the extragalactic objects PKS 2134 + 004, OQ 208, and NGC 1068 is due to emission from particles with small pitch angles or absorption by a thermal plasma or synchrotron self-absorption. It is concluded that the absorption interpretations cannot account for the turnover in the spectrum of PKS 2134 + 004. Measurements of polarization, angular structure, and X-ray flux are also described.

  11. Design of Synchrotron Light Source in Taiwan

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kuo, C. C.; Chang, H. P.; Chou, P. J.

    2007-01-19

    An intermediate energy synchrotron light source has been proposed. The goal is to construct a high performance light source in complementary to the existing 1.5 GeV synchrotron ring in Taiwan to boost the research capabilities. A 3 GeV machine with 518.4 m and 24-cell DBA lattice structure is considered and other options are also investigated. We report the 24-cell design considerations and its performances.

  12. Development of a health-related website for parents of children receiving hematopoietic stem cell transplant: HSCT-CHESS.

    PubMed

    Mayer, Deborah K; Ratichek, S; Berhe, H; Stewart, S; McTavish, F; Gustafson, D; Parsons, S K

    2010-03-01

    Parents of pediatric hematopoietic stem cell transplant (HSCT) play a pivotal role in the care of their child during and after transplant. In addition to the child's comforter, parents also serve as care coordinators and conduits of communication between various health care providers, family and community members. The stress on the parent and family is enormous during this process, which for many is compounded by geographic dislocation to accompany their child during the rigorous treatment and recovery process. For many parents, their own recovery spans months to years. Parental activation, a process of becoming informed to participate in decisions, collaborate with health care providers, and manage care provided the conceptual framework to develop an eHealth approach for this population. HSCT-CHESS was developed, based on previous success with an existing eHealth system of integrated services, the Comprehensive Health Enhancement Support System (CHESS). CHESS(TM) is designed to help individuals and families cope with a health crisis or medical concern. The iterative user-centered development process for HSCT-CHESS included parents of HSCT recipients, representatives from an HSCT Advocacy Group, and members of the clinical, research, development and design teams. This rigorous process, including online focus groups and surveys, utilization of a parental user group, and an editorial and development process are described. As the population of cancer survivors and caregivers increase and as the oncology workforce becomes more stretched; developing eHealth applications may be an approach to address many of caregivers unmet needs. The purpose in describing this process is to help others when considering such an endeavor. HSCT-CHESS is now being tested in a randomized controlled trial versus standard care to evaluate its impact on the quality of life of both the parent and child HSCT recipient.

  13. Optimal dimensionality reduction of complex dynamics: the chess game as diffusion on a free-energy landscape.

    PubMed

    Krivov, Sergei V

    2011-07-01

    Dimensionality reduction is ubiquitous in the analysis of complex dynamics. The conventional dimensionality reduction techniques, however, focus on reproducing the underlying configuration space, rather than the dynamics itself. The constructed low-dimensional space does not provide a complete and accurate description of the dynamics. Here I describe how to perform dimensionality reduction while preserving the essential properties of the dynamics. The approach is illustrated by analyzing the chess game--the archetype of complex dynamics. A variable that provides complete and accurate description of chess dynamics is constructed. The winning probability is predicted by describing the game as a random walk on the free-energy landscape associated with the variable. The approach suggests a possible way of obtaining a simple yet accurate description of many important complex phenomena. The analysis of the chess game shows that the approach can quantitatively describe the dynamics of processes where human decision-making plays a central role, e.g., financial and social dynamics.

  14. Expertise in complex decision making: the role of search in chess 70 years after de Groot.

    PubMed

    Connors, Michael H; Burns, Bruce D; Campitelli, Guillermo

    2011-01-01

    One of the most influential studies in all expertise research is de Groot's (1946) study of chess players, which suggested that pattern recognition, rather than search, was the key determinant of expertise. Many changes have occurred in the chess world since de Groot's study, leading some authors to argue that the cognitive mechanisms underlying expertise have also changed. We decided to replicate de Groot's study to empirically test these claims and to examine whether the trends in the data have changed over time. Six Grandmasters, five International Masters, six Experts, and five Class A players completed the think-aloud procedure for two chess positions. Findings indicate that Grandmasters and International Masters search more quickly than Experts and Class A players, and that both groups today search substantially faster than players in previous studies. The findings, however, support de Groot's overall conclusions and are consistent with predictions made by pattern recognition models. Copyright © 2011 Cognitive Science Society, Inc.

  15. Optimal dimensionality reduction of complex dynamics: The chess game as diffusion on a free-energy landscape

    NASA Astrophysics Data System (ADS)

    Krivov, Sergei V.

    2011-07-01

    Dimensionality reduction is ubiquitous in the analysis of complex dynamics. The conventional dimensionality reduction techniques, however, focus on reproducing the underlying configuration space, rather than the dynamics itself. The constructed low-dimensional space does not provide a complete and accurate description of the dynamics. Here I describe how to perform dimensionality reduction while preserving the essential properties of the dynamics. The approach is illustrated by analyzing the chess game—the archetype of complex dynamics. A variable that provides complete and accurate description of chess dynamics is constructed. The winning probability is predicted by describing the game as a random walk on the free-energy landscape associated with the variable. The approach suggests a possible way of obtaining a simple yet accurate description of many important complex phenomena. The analysis of the chess game shows that the approach can quantitatively describe the dynamics of processes where human decision-making plays a central role, e.g., financial and social dynamics.

  16. Validation of a Natural Language Processing Algorithm for Detecting Infectious Disease Symptoms in Primary Care Electronic Medical Records in Singapore.

    PubMed

    Hardjojo, Antony; Gunachandran, Arunan; Pang, Long; Abdullah, Mohammed Ridzwan Bin; Wah, Win; Chong, Joash Wen Chen; Goh, Ee Hui; Teo, Sok Huang; Lim, Gilbert; Lee, Mong Li; Hsu, Wynne; Lee, Vernon; Chen, Mark I-Cheng; Wong, Franco; Phang, Jonathan Siung King

    2018-06-11

    Free-text clinical records provide a source of information that complements traditional disease surveillance. To electronically harness these records, they need to be transformed into codified fields by natural language processing algorithms. The aim of this study was to develop, train, and validate Clinical History Extractor for Syndromic Surveillance (CHESS), an natural language processing algorithm to extract clinical information from free-text primary care records. CHESS is a keyword-based natural language processing algorithm to extract 48 signs and symptoms suggesting respiratory infections, gastrointestinal infections, constitutional, as well as other signs and symptoms potentially associated with infectious diseases. The algorithm also captured the assertion status (affirmed, negated, or suspected) and symptom duration. Electronic medical records from the National Healthcare Group Polyclinics, a major public sector primary care provider in Singapore, were randomly extracted and manually reviewed by 2 human reviewers, with a third reviewer as the adjudicator. The algorithm was evaluated based on 1680 notes against the human-coded result as the reference standard, with half of the data used for training and the other half for validation. The symptoms most commonly present within the 1680 clinical records at the episode level were those typically present in respiratory infections such as cough (744/7703, 9.66%), sore throat (591/7703, 7.67%), rhinorrhea (552/7703, 7.17%), and fever (928/7703, 12.04%). At the episode level, CHESS had an overall performance of 96.7% precision and 97.6% recall on the training dataset and 96.0% precision and 93.1% recall on the validation dataset. Symptoms suggesting respiratory and gastrointestinal infections were all detected with more than 90% precision and recall. CHESS correctly assigned the assertion status in 97.3%, 97.9%, and 89.8% of affirmed, negated, and suspected signs and symptoms, respectively (97.6% overall accuracy). Symptom episode duration was correctly identified in 81.2% of records with known duration status. We have developed an natural language processing algorithm dubbed CHESS that achieves good performance in extracting signs and symptoms from primary care free-text clinical records. In addition to the presence of symptoms, our algorithm can also accurately distinguish affirmed, negated, and suspected assertion statuses and extract symptom durations. ©Antony Hardjojo, Arunan Gunachandran, Long Pang, Mohammed Ridzwan Bin Abdullah, Win Wah, Joash Wen Chen Chong, Ee Hui Goh, Sok Huang Teo, Gilbert Lim, Mong Li Lee, Wynne Hsu, Vernon Lee, Mark I-Cheng Chen, Franco Wong, Jonathan Siung King Phang. Originally published in JMIR Medical Informatics (http://medinform.jmir.org), 11.06.2018.

  17. Sequencing chess

    NASA Astrophysics Data System (ADS)

    Atashpendar, Arshia; Schilling, Tanja; Voigtmann, Thomas

    2016-10-01

    We analyze the structure of the state space of chess by means of transition path sampling Monte Carlo simulations. Based on the typical number of moves required to transpose a given configuration of chess pieces into another, we conclude that the state space consists of several pockets between which transitions are rare. Skilled players explore an even smaller subset of positions that populate some of these pockets only very sparsely. These results suggest that the usual measures to estimate both the size of the state space and the size of the tree of legal moves are not unique indicators of the complexity of the game, but that considerations regarding the connectedness of states are equally important.

  18. Picosecond x-ray diagnostics for third and fourth generation synchrotron sources

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    DeCamp, Matthew

    2016-03-30

    In the DOE-EPSCoR State/National Laboratory partnership grant ``Picosecond x-ray diagnostics for third and fourth generation synchrotron sources'' Dr. DeCamp set forth a partnership between the University of Delaware and Argonne National Laboratory. This proposal aimed to design and implement a series of experiments utilizing, or improving upon, existing time-domain hard x-ray spectroscopies at a third generation synchrotron source. Specifically, the PI put forth three experimental projects to be explored in the grant cycle: 1) implementing a picosecond ``x-ray Bragg switch'' using a laser excited nano-structured metallic film, 2) designing a robust x-ray optical delay stage for x-ray pump-probe studies atmore » a hard x-ray synchrotron source, and 3) building/installing a laser based x-ray source at the Advanced Photon Source for two-color x-ray pump-probe studies.« less

  19. Fat-suppressed MR images of both hands obtained using CHESS can be improved by rice pads.

    PubMed

    Moriya, Susumu; Miki, Yukio; Kamishima, Tamotsu; Kanagaki, Mitsunori; Yokobayashi, Tsuneo; Ishikawa, Mitsunori

    2012-09-01

    When chemical shift selective (CHESS) imaging is used with magnetic resonance imaging (MRI) for simultaneous imaging of both hands for the evaluation of rheumatoid arthritis, the fat suppression effect is poor. We investigated whether these fat-suppressed images using CHESS could be improved with the use of rice pads. T1-weighted images were obtained with CHESS and the same imaging parameters were used with and without rice pads on the coronal plane of both hands in 10 healthy volunteers. Patients were placed in a prone position with both hands extended overhead. The fat-suppression effect was classified into four categories and scored for both sets of images, and visual assessments were made by one radiologist and one radiologic technologist. The evaluation score was 1.1 for the images made without rice pads, and 3.2 for the images made with rice pads. The fat suppression effect was thus significantly better in the images made using rice pads (P<0.0001). Lingering fat signals disappeared almost completely in images of both hands using CHESS with rice pads, and it was confirmed that the images were improved and had good fat suppression. More accurate evaluation of inflammatory sites that occur in rheumatoid arthritis may thus be possible, promising better diagnostic accuracy. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  20. It Takes Two–Skilled Recognition of Objects Engages Lateral Areas in Both Hemispheres

    PubMed Central

    Bilalić, Merim; Kiesel, Andrea; Pohl, Carsten; Erb, Michael; Grodd, Wolfgang

    2011-01-01

    Our object recognition abilities, a direct product of our experience with objects, are fine-tuned to perfection. Left temporal and lateral areas along the dorsal, action related stream, as well as left infero-temporal areas along the ventral, object related stream are engaged in object recognition. Here we show that expertise modulates the activity of dorsal areas in the recognition of man-made objects with clearly specified functions. Expert chess players were faster than chess novices in identifying chess objects and their functional relations. Experts' advantage was domain-specific as there were no differences between groups in a control task featuring geometrical shapes. The pattern of eye movements supported the notion that experts' extensive knowledge about domain objects and their functions enabled superior recognition even when experts were not directly fixating the objects of interest. Functional magnetic resonance imaging (fMRI) related exclusively the areas along the dorsal stream to chess specific object recognition. Besides the commonly involved left temporal and parietal lateral brain areas, we found that only in experts homologous areas on the right hemisphere were also engaged in chess specific object recognition. Based on these results, we discuss whether skilled object recognition does not only involve a more efficient version of the processes found in non-skilled recognition, but also qualitatively different cognitive processes which engage additional brain areas. PMID:21283683

  1. It's Your Move!

    ERIC Educational Resources Information Center

    Carlson, Greg

    2004-01-01

    A library collection is a community asset. Studies indicate that chess is a healthy mental pursuit for children of all skill levels; the educational nonprofit Chess-in-the-Schools. www.chessintheschool.org reports improvements in reading scores and a variety of other intellectual and social benefits for kids who accept the rigors and rewards of…

  2. CACTUS: Calculator and Computer Technology User Service.

    ERIC Educational Resources Information Center

    Hyde, Hartley

    1998-01-01

    Presents an activity in which students use computer-based spreadsheets to find out how much grain should be added to a chess board when a grain of rice is put on the first square, the amount is doubled for the next square, and the chess board is covered. (ASK)

  3. Overextension in Verb Conjunctions

    ERIC Educational Resources Information Center

    Jönsson, Martin L.

    2015-01-01

    Hampton (1988) discovered that people are subject to "overextension"--they categorize some things as falling under a conjunction (e.g., they categorize chess as a "sport which is also a game") but not as falling under both of the corresponding conjuncts (e.g., they do not categorize chess as a "sport"). Although…

  4. Assessing noise sources at synchrotron infrared ports

    PubMed Central

    Lerch, Ph.; Dumas, P.; Schilcher, T.; Nadji, A.; Luedeke, A.; Hubert, N.; Cassinari, L.; Boege, M.; Denard, J.-C.; Stingelin, L.; Nadolski, L.; Garvey, T.; Albert, S.; Gough, Ch.; Quack, M.; Wambach, J.; Dehler, M.; Filhol, J.-M.

    2012-01-01

    Today, the vast majority of electron storage rings delivering synchrotron radiation for general user operation offer a dedicated infrared port. There is growing interest expressed by various scientific communities to exploit the mid-IR emission in microspectroscopy, as well as the far infrared (also called THz) range for spectroscopy. Compared with a thermal (laboratory-based source), IR synchrotron radiation sources offer enhanced brilliance of about two to three orders of magnitude in the mid-IR energy range, and enhanced flux and brilliance in the far-IR energy range. Synchrotron radiation also has a unique combination of a broad wavelength band together with a well defined time structure. Thermal sources (globar, mercury filament) have excellent stability. Because the sampling rate of a typical IR Fourier-transform spectroscopy experiment is in the kHz range (depending on the bandwidth of the detector), instabilities of various origins present in synchrotron radiation sources play a crucial role. Noise recordings at two different IR ports located at the Swiss Light Source and SOLEIL (France), under conditions relevant to real experiments, are discussed. The lowest electron beam fluctuations detectable in IR spectra have been quantified and are shown to be much smaller than what is routinely recorded by beam-position monitors. PMID:22186638

  5. From the Blazar Sequence to the Blazar Envelope: Revisiting the Relativistic Jet Dichotomy in Radio-Loud AGN

    NASA Technical Reports Server (NTRS)

    Meyer, Eileen T.; Fossati, Giovanini; Georganopoulos, Markos; Lister, Matthew L.

    2012-01-01

    We revisit the concept of a blazar sequence that relates the synchrotron peak frequency (Vpeak) in blazars with synchrotron peak luminosity (Lpeak, in vLv) using a large sample of radio-loud AGN. We present observational evidence that the blazar sequence is formed from two populations in the synchrotron Vpeak - Lpeak plane, each forming an upper edge to an envelope of progressively misaligned blazars, and connecting to an adjacent group of radio galaxies having jets viewed at much larger angles to the line of sight. When binned by jet kinetic power (Lkin; as measured through a scaling relationship with extended radio power), we find that radio core dominance decreases with decreasing synchrotron Lpeak, revealing that sources in the envelope are generally more misaligned. We find population-based evidence of velocity gradients in jets at low kinetic powers (approximately 10(exp 42) - 10(exp 44.5) erg s(exp -1)), corresponding to FR I radio galaxies and most BL Lacs. These low jet power 'weak jet' sources, thought to exhibit radiatively inefficient accretion, are distinguished from the population of non-decelerating, low synchrotron-peaking (LSP) blazars and FR II radio galaxies ('strong' jets) which are thought to exhibit radiatively efficient accretion. The two-population interpretation explains the apparent contradiction of the existence of highly core-dominated, low-power blazars at both low and high synchrotron peak frequencies, and further implies that most intermediate synchrotron peak (ISP) sources are not intermediate in intrinsic jet power between LSP and high synchrotron-peaking (HSP) sources, but are more misaligned versions of HSP sources with similar jet powers.

  6. National Synchrotron Light Source annual report 1988

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hulbert, S.; Lazarz, N.; Williams, G.

    1988-01-01

    This report discusses the experiment done at the National Synchrotron Light Source. Most experiments discussed involves the use of the x-ray beams to study physical properties of solid materials. (LSP)

  7. Line-Editor Computer Program

    NASA Technical Reports Server (NTRS)

    Scott, Peter J.

    1989-01-01

    ZED editing program for DEC VAX computer simple, powerful line editor for text, program source code, and nonbinary data. Excels in processing of text by use of procedure files. Also features versatile search qualifiers, global changes, conditionals, online help, hexadecimal mode, space compression, looping, logical combinations of search strings, journaling, visible control characters, and automatic detabbing. Users of Cambridge implementation devised such ZED procedures as chess games, calculators, and programs for evaluating pi. Written entirely in C.

  8. Stalemate: Girls and a Mixed-Gender Chess Club.

    ERIC Educational Resources Information Center

    Galitis, Ingrid

    2002-01-01

    Observed and conducted discussions with female members of an elementary-level, mixed-gender, Australian chess club to investigate why girls left and boys came to dominate the club. Results indicated that both home values and schooling transmitted and reinforced inequalities between the sexes, though in more subtle and less overt forms than in the…

  9. It's Your Move: Offering Seminars to Teach Strategy Games.

    ERIC Educational Resources Information Center

    Moore, Rhonda Bodine

    1994-01-01

    Gifted elementary students at the Center for Gifted Education in Columbia, Missouri, participated in a seminar designed to teach them the fundamentals of chess and other strategy board games. Students learned that beginning chess is accessible to everyone, learned problem solving and concentration, and created their own strategy board games. (JDD)

  10. Mechanisms and Neural Basis of Object and Pattern Recognition: A Study with Chess Experts

    ERIC Educational Resources Information Center

    Bilalic, Merim; Langner, Robert; Erb, Michael; Grodd, Wolfgang

    2010-01-01

    Comparing experts with novices offers unique insights into the functioning of cognition, based on the maximization of individual differences. Here we used this expertise approach to disentangle the mechanisms and neural basis behind two processes that contribute to everyday expertise: object and pattern recognition. We compared chess experts and…

  11. Meta-analysis of age and skill effects on recalling chess positions and selecting the best move.

    PubMed

    Moxley, Jerad H; Charness, Neil

    2013-10-01

    A meta-analysis was conducted of studies that measured the effects of both age and skill in chess on the tasks of selecting the best move for chess positions (the best move task) as well as recalling chess game positions (the recall task). Despite a small sample of studies, we demonstrated that there are age and skill effects on both tasks: age being negatively associated with performance on both tasks and skill being positively associated with performance on both tasks. On the best move task, we found that skill was the dominant effect, while on the recall task, skill and age were approximately equally strong effects. We also found that skill was best measured by the best move task. In the case of the best move task, this result is consistent with the argument that it accurately replicates expert performance (Ericsson & Smith, 1991). Results for the recall task argue that this task captures effects related to skill, but also effects likely due to a general aging process. Implications for our understanding of aging in skilled domains are also discussed.

  12. Reduced caudate volume and enhanced striatal-DMN integration in chess experts.

    PubMed

    Duan, Xujun; He, Sheng; Liao, Wei; Liang, Dongmei; Qiu, Lihua; Wei, Luqing; Li, Yuan; Liu, Chengyi; Gong, Qiyong; Chen, Huafu

    2012-04-02

    The superior capability of chess experts largely depends on quick automatic processing skills which are considered to be mediated by the caudate nucleus. We asked whether continued practice or rehearsal of the skill over a long period of time can lead to structural changes in this region. We found that, comparing to novice controls, grandmaster and master level Chinese chess players (GM/Ms), who had a mean period of over 10years of tournament and training practice, exhibited significant smaller gray-matter volume in the bilateral caudate nuclei. When these regions were used as seeds in functional connectivity analysis in resting-state fMRI, significantly enhanced integration was found in GM/Ms between the caudate and the default mode network (DMN), a constellation of brain areas important for goal-directed cognitive performance and theory of mind. These findings demonstrate the structural changes in the caudate nucleus in response to its extensive engagement in chess problem solving, and its enhanced functional integration with widely distributed circuitry to better support high-level cognitive control of behavior. Copyright © 2012 Elsevier Inc. All rights reserved.

  13. The role of domain-specific practice, handedness, and starting age in chess.

    PubMed

    Gobet, Fernand; Campitelli, Guillermo

    2007-01-01

    The respective roles of the environment and innate talent have been a recurrent question for research into expertise. The authors investigated markers of talent, environment, and critical period for the acquisition of expert performance in chess. Argentinian chess players (N = 104), ranging from weak amateurs to grandmasters, completed a questionnaire measuring variables including individual and group practice, starting age, and handedness. The study reaffirms the importance of practice for reaching high levels of performance, but it also indicates a large variability: The slower player needed 8 times as much practice to reach master level than the faster player. Additional results show a correlation between skill and starting age and indicate that players are more likely to be mixed-handed than individuals in the general population; however, there was no correlation between handedness and skill within the sample of chess players. Together, these results suggest that practice is a necessary but not sufficient condition for the acquisition of expertise, that some additional factors may differentiate chessplayers and nonchessplayers, and that starting age of practice is important. Copyright 2006 APA, all rights reserved.

  14. A comparative quantitative analysis of the IDEAL (iterative decomposition of water and fat with echo asymmetry and least-squares estimation) and the CHESS (chemical shift selection suppression) techniques in 3.0 T L-spine MRI

    NASA Astrophysics Data System (ADS)

    Kim, Eng-Chan; Cho, Jae-Hwan; Kim, Min-Hye; Kim, Ki-Hong; Choi, Cheon-Woong; Seok, Jong-min; Na, Kil-Ju; Han, Man-Seok

    2013-03-01

    This study was conducted on 20 patients who had undergone pedicle screw fixation between March and December 2010 to quantitatively compare a conventional fat suppression technique, CHESS (chemical shift selection suppression), and a new technique, IDEAL (iterative decomposition of water and fat with echo asymmetry and least squares estimation). The general efficacy and usefulness of the IDEAL technique was also evaluated. Fat-suppressed transverse-relaxation-weighed images and longitudinal-relaxation-weighted images were obtained before and after contrast injection by using these two techniques with a 1.5T MR (magnetic resonance) scanner. The obtained images were analyzed for image distortion, susceptibility artifacts and homogenous fat removal in the target region. The results showed that the image distortion due to the susceptibility artifacts caused by implanted metal was lower in the images obtained using the IDEAL technique compared to those obtained using the CHESS technique. The results of a qualitative analysis also showed that compared to the CHESS technique, fewer susceptibility artifacts and more homogenous fat removal were found in the images obtained using the IDEAL technique in a comparative image evaluation of the axial plane images before and after contrast injection. In summary, compared to the CHESS technique, the IDEAL technique showed a lower occurrence of susceptibility artifacts caused by metal and lower image distortion. In addition, more homogenous fat removal was shown in the IDEAL technique.

  15. Effect of Computer Support on Younger Women with Breast Cancer

    PubMed Central

    Gustafson, David H; Hawkins, Robert; Pingree, Suzanne; McTavish, Fiona; Arora, Neeraj K; Mendenhall, John; Cella, David F; Serlin, Ronald C; Apantaku, Funmi M; Stewart, James; Salner, Andrew

    2001-01-01

    OBJECTIVE Assess impact of a computer-based patient support system on quality of life in younger women with breast cancer, with particular emphasis on assisting the underserved. DESIGN Randomized controlled trial conducted between 1995 and 1998. SETTING Five sites: two teaching hospitals (Madison, Wis, and Chicago, Ill), two nonteaching hospitals (Chicago), and a cancer resource center (Indianapolis, Ill). The latter three sites treat many underserved patients. PARTICIPANTS Newly diagnosed breast cancer patients (N = 246) under age 60. INTERVENTIONS Experimental group received Comprehensive Health Enhancement Support System (CHESS), a home-based computer system providing information, decision-making, and emotional support. MEASUREMENTS AND MAIN RESULTS Pretest and two post-test surveys (at two- and five-month follow-up) measured aspects of participation in care, social/information support, and quality of life. At two-month follow-up, the CHESS group was significantly more competent at seeking information, more comfortable participating in care, and had greater confidence in doctor(s). At five-month follow-up, the CHESS group had significantly better social support and also greater information competence. In addition, experimental assignment interacted with several indicators of medical underservice (race, education, and lack of insurance), such that CHESS benefits were greater for the disadvantaged than the advantaged group. CONCLUSIONS Computer-based patient support systems such as CHESS may benefit patients by providing information and social support, and increasing their participation in health care. These benefits may be largest for currently underserved populations. PMID:11520380

  16. The effect of bundling medication-assisted treatment for opioid addiction with mHealth: study protocol for a randomized clinical trial.

    PubMed

    Gustafson, David H; Landucci, Gina; McTavish, Fiona; Kornfield, Rachel; Johnson, Roberta A; Mares, Marie-Louise; Westergaard, Ryan P; Quanbeck, Andrew; Alagoz, Esra; Pe-Romashko, Klaren; Thomas, Chantelle; Shah, Dhavan

    2016-12-12

    Opioid dependence has devastating and increasingly widespread consequences and costs, and the most common outcome of treatment is early relapse. People who inject opioids are also at disproportionate risk for contracting the human immunodeficiency virus (HIV) and hepatitis C virus (HCV). This study tests an approach that has been shown to improve recovery rates: medication along with other supportive services (medication-assisted treatment, or MAT) against MAT combined with a smartphone innovation called A-CHESS (MAT + A-CHESS). This unblinded study will randomly assign 440 patients to receive MAT + A-CHESS or MAT alone. Eligible patients will meet criteria for having an opioid use disorder of at least moderate severity and will be taking methadone, injectable naltrexone, or buprenorphine. Patients with A-CHESS will have smartphones for 16 months; all patients will be followed for 24 months. The primary outcome is the difference between patients in the two arms in percentage of days using illicit opioids during the 24-month intervention. Secondary outcomes are differences between patients receiving MAT + A-CHESS versus MAT in other substance use, quality of life, retention in treatment, health service use, and, related to HIV and HCV, screening and testing rates, medication adherence, risk behaviors, and links to care. We will also examine mediators and moderators of the effects of MAT + A-CHESS. We will measure variables at baseline and months 4, 8, 12, 16, 20, and 24. At each point, patients will respond to a 20- to 30-min phone survey; urine screens will be collected at baseline and up to twice a month thereafter. We will use mixed-effects to evaluate the primary and secondary outcomes, with baseline scores functioning as covariates, treatment condition as a between-subject factor, and the outcomes reflecting scores for a given assessment at the six time points. Separate analyses will be conducted for each outcome. A-CHESS has been shown to improve recovery for people with alcohol dependence. It offers an adaptive and extensive menu of services and can attend to patients nearly as constantly as addiction does. This suggests the possibility of increasing both the effectiveness of, and access to, treatment for opioid dependence. ClinicalTrials.gov, NCT02712034 . Registered on 14 March 2016.

  17. RoboPol: the optical polarization of gamma-ray-loud and gamma-ray-quiet blazars

    NASA Astrophysics Data System (ADS)

    Angelakis, E.; Hovatta, T.; Blinov, D.; Pavlidou, V.; Kiehlmann, S.; Myserlis, I.; Böttcher, M.; Mao, P.; Panopoulou, G. V.; Liodakis, I.; King, O. G.; Baloković, M.; Kus, A.; Kylafis, N.; Mahabal, A.; Marecki, A.; Paleologou, E.; Papadakis, I.; Papamastorakis, I.; Pazderski, E.; Pearson, T. J.; Prabhudesai, S.; Ramaprakash, A. N.; Readhead, A. C. S.; Reig, P.; Tassis, K.; Urry, M.; Zensus, J. A.

    2016-12-01

    We present average R-band optopolarimetric data, as well as variability parameters, from the first and second RoboPol observing season. We investigate whether gamma-ray-loud and gamma-ray-quiet blazars exhibit systematic differences in their optical polarization properties. We find that gamma-ray-loud blazars have a systematically higher polarization fraction (0.092) than gamma-ray-quiet blazars (0.031), with the hypothesis of the two samples being drawn from the same distribution of polarization fractions being rejected at the 3σ level. We have not found any evidence that this discrepancy is related to differences in the redshift distribution, rest-frame R-band luminosity density, or the source classification. The median polarization fraction versus synchrotron-peak-frequency plot shows an envelope implying that high-synchrotron-peaked sources have a smaller range of median polarization fractions concentrated around lower values. Our gamma-ray-quiet sources show similar median polarization fractions although they are all low-synchrotron-peaked. We also find that the randomness of the polarization angle depends on the synchrotron peak frequency. For high-synchrotron-peaked sources, it tends to concentrate around preferred directions while for low-synchrotron-peaked sources, it is more variable and less likely to have a preferred direction. We propose a scenario which mediates efficient particle acceleration in shocks and increases the helical B-field component immediately downstream of the shock.

  18. The effects of combining Web-based eHealth with telephone nurse case management for pediatric asthma control: a randomized controlled trial.

    PubMed

    Gustafson, David; Wise, Meg; Bhattacharya, Abhik; Pulvermacher, Alice; Shanovich, Kathleen; Phillips, Brenda; Lehman, Erik; Chinchilli, Vernon; Hawkins, Robert; Kim, Jee-Seon

    2012-07-26

    Asthma is the most common pediatric illness in the United States, burdening low-income and minority families disproportionately and contributing to high health care costs. Clinic-based asthma education and telephone case management have had mixed results on asthma control, as have eHealth programs and online games. To test the effects of (1) CHESS+CM, a system for parents and children ages 4-12 years with poorly controlled asthma, on asthma control and medication adherence, and (2) competence, self-efficacy, and social support as mediators. CHESS+CM included a fully automated eHealth component (Comprehensive Health Enhancement Support System [CHESS]) plus monthly nurse case management (CM) via phone. CHESS, based on self-determination theory, was designed to improve competence, social support, and intrinsic motivation of parents and children. We identified eligible parent-child dyads from files of managed care organizations in Madison and Milwaukee, Wisconsin, USA, sent them recruitment letters, and randomly assigned them (unblinded) to a control group of treatment as usual plus asthma information or to CHESS+CM. Asthma control was measured by the Asthma Control Questionnaire (ACQ) and self-reported symptom-free days. Medication adherence was a composite of pharmacy refill data and medication taking. Social support, information competence, and self-efficacy were self-assessed in questionnaires. All data were collected at 0, 3, 6, 9, and 12 months. Asthma diaries kept during a 3-week run-in period before randomization provided baseline data. Of 305 parent-child dyads enrolled, 301 were randomly assigned, 153 to the control group and 148 to CHESS+CM. Most parents were female (283/301, 94%), African American (150/301, 49.8%), and had a low income as indicated by child's Medicaid status (154/301, 51.2%); 146 (48.5%) were single and 96 of 301 (31.9%) had a high school education or less. Completion rates were 127 of 153 control group dyads (83.0%) and 132 of 148 CHESS+CM group dyads (89.2%). CHESS+CM group children had significantly better asthma control on the ACQ (d = -0.31, 95% confidence limits [CL] -0.56, -0.06, P = .011), but not as measured by symptom-free days (d = 0.18, 95% CL -0.88, 1.60, P = 1.00). The composite adherence scores did not differ significantly between groups (d = 1.48%, 95% CL -8.15, 11.11, P = .76). Social support was a significant mediator for CHESS+CM's effect on asthma control (alpha = .200, P = .01; beta = .210, P = .03). Self-efficacy was not significant (alpha = .080, P = .14; beta = .476, P = .01); neither was information competence (alpha = .079, P = .09; beta = .063, P = .64). Integrating telephone case management with eHealth benefited pediatric asthma control, though not medication adherence. Improved methods of measuring medication adherence are needed. Social support appears to be more effective than information in improving pediatric asthma control. Clinicaltrials.gov NCT00214383; http://clinicaltrials.gov/ct2/show/NCT00214383 (Archived by WebCite at http://www.webcitation.org/68OVwqMPz).

  19. National Synchrotron Light Source

    ScienceCinema

    None

    2017-12-09

    A tour of Brookhaven's National Synchrotron Light Source (NSLS). The NSLS is one of the world's most widely used scientific research facilities, hosting more than 2,500 guest researchers each year. The NSLS provides intense beams of infrared, ultraviole

  20. The Effects of Chess Instruction on the Mathematics Achievement of Southern, Rural, Black Secondary Students.

    ERIC Educational Resources Information Center

    Smith, James P.; Cage. Bob N.

    2000-01-01

    Studied the effects of 120 hours of chess instruction on the mathematics achievement of southern, rural, black secondary students. Analysis of covariance results show the treatment group (11 females, 9 males) scored significantly higher than the control group (10 females, 10 males) in mathematics achievement. Discusses results in terms of altering…

  1. Our Move: Using Chess to Improve Math Achievement for Students Who Receive Special Education Services

    ERIC Educational Resources Information Center

    Barrett, David C.; Fish, Wade W.

    2011-01-01

    This causal-comparative study evaluated a 30-week chess instructional program implemented within special education math classes for students in the sixth, seventh, and eighth grades in a suburban middle school located in the southwestern United States. An analysis of covariance (ANCOVA) was utilized to compare the adjusted means for the comparison…

  2. The Impact of Chess Instruction on the Critical Thinking Ability and Mathematical Achievement of Developmental Mathematics Students

    ERIC Educational Resources Information Center

    Berkley, Darrin K.

    2012-01-01

    This sequential explanatory mixed-methods study determined whether the game of chess can be used as an educational tool to improve critical thinking skills of developmental mathematics students and improve mathematics achievement for these students. Five research questions were investigated. These questions were as follows: (a) Is there a…

  3. High resolution, monochromatic x-ray topography capability at CHESS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Finkelstein, K. D., E-mail: kdf1@cornell.edu; Pauling, A.; Brown, Z.

    2016-07-27

    CHESS has a monochromatic x-ray topography capability serving continually expanding user interest. The setup consists of a beam expanding monochromator, 6-circle diffactometer, and CHESS designed CMOS camera with real time sample-alignment capability. This provides rocking curve mapping with angle resolution as small as 2 µradians, spatial resolution to 3 microns, and field of view up to 7mm. Thus far the capability has been applied for: improving CVD-diamond growth, evaluating perfection of ultra-thin diamond membranes, correlating performance of diamond-based electronics with crystal defect structure, and defect analysis of single crystal silicon carbide. This paper describes our topography system, explains its capabilities,more » and presents experimental results from several applications.« less

  4. Examining Returned Samples in their Collection Tubes Using Synchrotron Radiation-Based Techniques

    NASA Astrophysics Data System (ADS)

    Schoonen, M. A.; Hurowitz, J. A.; Thieme, J.; Dooryhee, E.; Fogelqvist, E.; Gregerson, J.; Farley, K. A.; Sherman, S.; Hill, J.

    2018-04-01

    Synchrotron radiation-based techniques can be leveraged for triaging and analysis of returned samples before unsealing collection tubes. Proof-of-concept measurements conducted at Brookhaven National Lab's National Synchrotron Light Source-II.

  5. The CHESS score: a simple tool for early prediction of shunt dependency after aneurysmal subarachnoid hemorrhage.

    PubMed

    Jabbarli, R; Bohrer, A-M; Pierscianek, D; Müller, D; Wrede, K H; Dammann, P; El Hindy, N; Özkan, N; Sure, U; Müller, O

    2016-05-01

    Acute hydrocephalus is an early and common complication of aneurysmal subarachnoid hemorrhage (SAH). However, considerably fewer patients develop chronic hydrocephalus requiring shunt placement. Our aim was to develop a risk score for early identification of patients with shunt dependency after SAH. Two hundred and forty-two SAH individuals who were treated in our institution between January 2008 and December 2013 and survived the initial impact were retrospectively analyzed. Clinical parameters within 72 h after the ictus were correlated with shunt dependency. Independent predictors were summarized into a new risk score which was validated in a subsequent SAH cohort treated between January and December 2014. Seventy-five patients (31%) underwent shunt placement. Of 23 evaluated variables, only the following five showed independent associations with shunt dependency and were subsequently used to establish the Chronic Hydrocephalus Ensuing from SAH Score (CHESS, 0-8 points): Hunt and Hess grade ≥IV (1 point), location of the ruptured aneurysm in the posterior circulation (1 point), acute hydrocephalus (4 points), the presence of intraventricular hemorrhage (1 point) and early cerebral infarction on follow-up computed tomography scan (1 point). The CHESS showed strong correlation with shunt dependency (P = 0.0007) and could be successfully validated in both internal SAH cohorts tested. Patients scoring ≥6 CHESS points had significantly higher risk of shunt dependency (P < 0.0001) than other patients. The CHESS may become a valuable diagnostic tool for early estimation of shunt dependency after SAH. Further evaluation and external validation will be required in prospective studies. © 2016 EAN.

  6. Move-by-move dynamics of the advantage in chess matches reveals population-level learning of the game.

    PubMed

    Ribeiro, Haroldo V; Mendes, Renio S; Lenzi, Ervin K; del Castillo-Mussot, Marcelo; Amaral, Luís A N

    2013-01-01

    The complexity of chess matches has attracted broad interest since its invention. This complexity and the availability of large number of recorded matches make chess an ideal model systems for the study of population-level learning of a complex system. We systematically investigate the move-by-move dynamics of the white player's advantage from over seventy thousand high level chess matches spanning over 150 years. We find that the average advantage of the white player is positive and that it has been increasing over time. Currently, the average advantage of the white player is 0.17 pawns but it is exponentially approaching a value of 0.23 pawns with a characteristic time scale of 67 years. We also study the diffusion of the move dependence of the white player's advantage and find that it is non-Gaussian, has long-ranged anti-correlations and that after an initial period with no diffusion it becomes super-diffusive. We find that the duration of the non-diffusive period, corresponding to the opening stage of a match, is increasing in length and exponentially approaching a value of 15.6 moves with a characteristic time scale of 130 years. We interpret these two trends as a resulting from learning of the features of the game. Additionally, we find that the exponent [Formula: see text] characterizing the super-diffusive regime is increasing toward a value of 1.9, close to the ballistic regime. We suggest that this trend is due to the increased broadening of the range of abilities of chess players participating in major tournaments.

  7. When Words were Wanted, But Woefully Wanting, We Waged War With Chess.

    PubMed

    Seitler, Burton Norman

    2016-12-01

    What do you say to a child who rarely speaks? How do you work with such a youngster? What are the sine qua nons or guiding principles upon which analysts can draw? And, how do we know if we are being helpful? Sam was 9-years when I began treating him. He was extremely withdrawn and rarely spoke more than a few words. Instead, he mainly played chess. I did not know at first whether Sam's taciturn demeanor was due to shyness, limited verbal abilities, or the stultifying effects of trauma. Fortuitously, during one of many seemingly "innocent" games of chess, Sam happened to make a bold move, to which I admiringly remarked, "What a move, you're killing me." His surprising reaction permanently altered the trajectory of treatment. Curiously, upon returning from summer vacation, not only did Sam no longer need to play chess, but he also found his voice. It was then that he began to discuss things for the first time. Initially, what he said was cloaked in symbolic and indirect referents, suggesting that there were things about which he still could not speak. I proceeded with patience and eventually Sam was able to disclose what he had been harboring inside. In this article, I will discuss the role and psychoanalytic meaning of chess in Sam's play therapy and how it served as a means of symbolically expressing an unspoken, yet ongoing trauma; how it non-verbally, and thus safely communicated Sam's desperate need for understanding and his urgent (but silent) disguised plea for help.

  8. Move-by-Move Dynamics of the Advantage in Chess Matches Reveals Population-Level Learning of the Game

    PubMed Central

    Ribeiro, Haroldo V.; Mendes, Renio S.; Lenzi, Ervin K.; del Castillo-Mussot, Marcelo; Amaral, Luís A. N.

    2013-01-01

    The complexity of chess matches has attracted broad interest since its invention. This complexity and the availability of large number of recorded matches make chess an ideal model systems for the study of population-level learning of a complex system. We systematically investigate the move-by-move dynamics of the white player’s advantage from over seventy thousand high level chess matches spanning over 150 years. We find that the average advantage of the white player is positive and that it has been increasing over time. Currently, the average advantage of the white player is 0.17 pawns but it is exponentially approaching a value of 0.23 pawns with a characteristic time scale of 67 years. We also study the diffusion of the move dependence of the white player’s advantage and find that it is non-Gaussian, has long-ranged anti-correlations and that after an initial period with no diffusion it becomes super-diffusive. We find that the duration of the non-diffusive period, corresponding to the opening stage of a match, is increasing in length and exponentially approaching a value of 15.6 moves with a characteristic time scale of 130 years. We interpret these two trends as a resulting from learning of the features of the game. Additionally, we find that the exponent characterizing the super-diffusive regime is increasing toward a value of 1.9, close to the ballistic regime. We suggest that this trend is due to the increased broadening of the range of abilities of chess players participating in major tournaments. PMID:23382876

  9. Decision support for the selection of reference sites using 137Cs as a soil erosion tracer

    NASA Astrophysics Data System (ADS)

    Arata, Laura; Meusburger, Katrin; Bürge, Alexandra; Zehringer, Markus; Ketterer, Michael E.; Mabit, Lionel; Alewell, Christine

    2017-08-01

    The classical approach of using 137Cs as a soil erosion tracer is based on the comparison between stable reference sites and sites affected by soil redistribution processes; it enables the derivation of soil erosion and deposition rates. The method is associated with potentially large sources of uncertainty with major parts of this uncertainty being associated with the selection of the reference sites. We propose a decision support tool to Check the Suitability of reference Sites (CheSS). Commonly, the variation among 137Cs inventories of spatial replicate reference samples is taken as the sole criterion to decide on the suitability of a reference inventory. Here we propose an extension of this procedure using a repeated sampling approach, in which the reference sites are resampled after a certain time period. Suitable reference sites are expected to present no significant temporal variation in their decay-corrected 137Cs depth profiles. Possible causes of variation are assessed by a decision tree. More specifically, the decision tree tests for (i) uncertainty connected to small-scale variability in 137Cs due to its heterogeneous initial fallout (such as in areas affected by the Chernobyl fallout), (ii) signs of erosion or deposition processes and (iii) artefacts due to the collection, preparation and measurement of the samples; (iv) finally, if none of the above can be assigned, this variation might be attributed to turbation processes (e.g. bioturbation, cryoturbation and mechanical turbation, such as avalanches or rockfalls). CheSS was exemplarily applied in one Swiss alpine valley where the apparent temporal variability called into question the suitability of the selected reference sites. In general we suggest the application of CheSS as a first step towards a comprehensible approach to test for the suitability of reference sites.

  10. Next-generation materials for future synchrotron and free-electron laser sources

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Assoufid, Lahsen; Graafsma, Heinz

    We show that the development of new materials and improvements of existing ones are at the root of the spectacular recent developments of new technologies for synchrotron storage rings and free-electron laser sources. This holds true for all relevant application areas, from electron guns to undulators, x-ray optics, and detectors. As demand grows for more powerful and efficient light sources, efficient optics, and high-speed detectors, an overview of ongoing materials research for these applications is timely. In this article, we focus on the most exciting and demanding areas of materials research and development for synchrotron radiation optics and detectors. Materialsmore » issues of components for synchrotron and free-electron laser accelerators are briefly discussed. Lastly, the articles in this issue expand on these topics.« less

  11. Next-generation materials for future synchrotron and free-electron laser sources

    DOE PAGES

    Assoufid, Lahsen; Graafsma, Heinz

    2017-06-09

    We show that the development of new materials and improvements of existing ones are at the root of the spectacular recent developments of new technologies for synchrotron storage rings and free-electron laser sources. This holds true for all relevant application areas, from electron guns to undulators, x-ray optics, and detectors. As demand grows for more powerful and efficient light sources, efficient optics, and high-speed detectors, an overview of ongoing materials research for these applications is timely. In this article, we focus on the most exciting and demanding areas of materials research and development for synchrotron radiation optics and detectors. Materialsmore » issues of components for synchrotron and free-electron laser accelerators are briefly discussed. Lastly, the articles in this issue expand on these topics.« less

  12. National Synchrotron Light Source II

    ScienceCinema

    Steve Dierker

    2017-12-09

    The National Synchrotron Light Source II (NSLS-II) at the U.S. Department of Energy's Brookhaven National Laboratory is a proposed new state-of-the-art medium energy storage ring designed to deliver world-leading brightness and flux with top-off operation

  13. Linking Extreme Precocity and Adult Eminence: A Study of Eight Prodigies at International Chess

    ERIC Educational Resources Information Center

    Howard, Robert W.

    2008-01-01

    Do prodigies have extraordinary innate talent or do they just start very early and get much practice? Why do relatively few become eminent as adults? Is it because early and later success often need somewhat different abilities and gatekeepers rule? International chess is a good test domain for both issues because it has objective longitudinal…

  14. Examining the Impact of Chess Instruction for the Visual Impairment on Mathematics

    ERIC Educational Resources Information Center

    Aydin, Mensure

    2015-01-01

    The purpose of the study is to explore the impact of chess instruction for visually impaired children on math achievement. The study group consists of a total of 26 visually impaired students from inclusion classes in inclusive secondary schools of MoNE (Ministry of National Education), 9 male and 5 female students in the experiment group and 8…

  15. Women Managers in Higher Education: Summary Report of the ACU-CHESS Steering Committee Meeting (London, England, United Kingdom, May 25-27, 1993).

    ERIC Educational Resources Information Center

    Commonwealth Secretariat, London (England).

    This publication describes a meeting of the Association of Commonwealth Universities (ACU) and the Commonwealth Higher Education Support Scheme (CHESS) to design an agenda to facilitate the advancement of women administrators in Commonwealth universities, to further use of their skills in contributing to university development, and to increasing…

  16. Learning curves in highly skilled chess players: a test of the generality of the power law of practice.

    PubMed

    Howard, Robert W

    2014-09-01

    The power law of practice holds that a power function best interrelates skill performance and amount of practice. However, the law's validity and generality are moot. Some researchers argue that it is an artifact of averaging individual exponential curves while others question whether the law generalizes to complex skills and to performance measures other than response time. The present study tested the power law's generality to development over many years of a very complex cognitive skill, chess playing, with 387 skilled participants, most of whom were grandmasters. A power or logarithmic function best fit grouped data but individuals showed much variability. An exponential function usually was the worst fit to individual data. Groups differing in chess talent were compared and a power function best fit the group curve for the more talented players while a quadratic function best fit that for the less talented. After extreme amounts of practice, a logarithmic function best fit grouped data but a quadratic function best fit most individual curves. Individual variability is great and the power law or an exponential law are not the best descriptions of individual chess skill development. Copyright © 2014 Elsevier B.V. All rights reserved.

  17. Magnetic measurements of the injector synchrotron magnets for the advanced photon source

    NASA Astrophysics Data System (ADS)

    Kim, S. H.; Carnegie, D. W.; Doose, C. L.; Hogrefe, R.; Kim, K.; Merl, R.; Turner, L. R.

    1994-07-01

    The magnetic measurement data of the dipole, quadrupole, and sextupole magnets for the Advanced Photon Source injector synchrotron are summarized. Magnet design and magnetic measurements of the field strength, field shape, and multipole coefficients are described.

  18. Diffraction and Transmission Synchrotron Imaging at the German Light Source ANKA--Potential Industrial Applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rack, Alexander; Weitkamp, Timm; European Synchrotron Radiation Facility, BP 220, F-38043 Grenoble Cedex

    2009-03-10

    Diffraction and transmission synchrotron imaging methods have proven to be highly suitable for investigations in materials research and non-destructive evaluation. The high flux and spatial coherence of X-rays from modern synchrotron light sources allows one to work using high resolution and different contrast modalities. This article gives a short overview of different transmission and diffraction imaging methods with high potential for industrial applications, now available for commercial access via the German light source ANKA (Forschungszentrum Karlsruhe) and its new department ANKA Commercial Service (ANKA COS, http://www.anka-cos.de)

  19. Shielding calculations for the National Synchrotron Light Source-II experimental beamlines

    NASA Astrophysics Data System (ADS)

    Job, Panakkal K.; Casey, William R.

    2013-01-01

    Brookhaven National Laboratory is in the process of building a new Electron storage ring for scientific research using synchrotron radiation. This facility, called the "National Synchrotron Light Source II" (NSLS-II), will provide x-ray radiation of ultra-high brightness and exceptional spatial and energy resolution. It will also provide advanced insertion devices, optics, detectors, and robotics, designed to maximize the scientific output of the facility. The project scope includes the design of an electron storage ring and the experimental beamlines, which stores a maximum of 500 mA electron beam current at an energy of 3.0 GeV. When fully built there will be at least 58 beamlines using synchrotron radiation for experimental programs. It is planned to operate the facility primarily in a top-off mode, thereby maintaining the maximum variation in the synchrotron radiation flux to <1%. Because of the very demanding requirements for synchrotron radiation brilliance for the experiments, each of the 58 beamlines will be unique in terms of the source properties and experimental configuration. This makes the shielding configuration of each of the beamlines unique. The shielding calculation methodology and the results for five representative beamlines of NSLS-II, have been presented in this paper.

  20. Commissioning and Early Operation for the NSLS-II Booster RF System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marques, C.; Cupolo, J.; Davila, P.

    2015-05-03

    The National Synchrotron Light Source II (NSLS-II) at Brookhaven National Laboratory (BNL) is a third generation 3GeV, 500mA synchrotron light source. We discuss the booster synchrotron RF system responsible for providing power to accelerate an electron beam from 200MeV to 3GeV. The RF system design and construction are complete and is currently in the operational phase of the NSLS-II project. Preliminary operational data is also discussed.

  1. Fluorescence tomography using synchrotron radiation at the NSLS

    NASA Astrophysics Data System (ADS)

    Boisseau, P.; Grodzins, L.

    1987-03-01

    Fluorescence tomography utilizing focussed, tunable, monoenergetic X-rays from synchrotron light sources hold the promise of a non-invasive analytic tool for studying trace elements in specimens, particularly biological, at spatial resolutions of the order of micrometers. This note reports an early test at the National Synchrotron Light Source at Brookhaven National Laboratories in which fluorescence tomographic scans were successfully made of trace elements of iron and titanium in NBS standard glass and in a bee.

  2. The Impact of Scholastic Instrumental Music and Scholastic Chess Study on the Standardized Test Scores of Students in Grades Three, Four, and Five

    ERIC Educational Resources Information Center

    Martinez, Edwin E.

    2012-01-01

    This study examines the impact of instrumental music study and group chess lessons on the standardized test scores of suburban elementary public school students (grades three through five) in Levittown, New York. The study divides the students into the following groups and compares the standardized test scores of each: a) instrumental music…

  3. Building beyond the Evaluation Of Environmental Education and Sustainable Development in African Schools and Communities: The Women Global Green Action Network (WGGAN) Africa Perspective

    ERIC Educational Resources Information Center

    Enie, Rosemary Olive Mbone

    2006-01-01

    This article describes the Community Health Education and School Sanitation (CHESS) Project, an initiative by the Women Global Green Action Network International to support community-based environmental projects in Africa. The CHESS Project uses women, children and youth to develop more sustainable health and sanitation systems in urban and rural…

  4. Friendship through Interaction and Interaction through Friendship: Manifestations of Positive Politeness and Footing Changes in the Interaction of Two Friends Playing Chess

    ERIC Educational Resources Information Center

    Shigenaga, Yasumasa

    2016-01-01

    The present study uses a video recording of two friends playing chess to observe, through the concept of "positive politeness, what strategies the participants employ to construct and maintain their relationship as close friends during an activity that includes moments of heightened tension. The study also examines the dynamics of the…

  5. Synchrotron Radiation from Ultra-High Energy Protons and the Fermi Observations of GRB 080916C

    DTIC Science & Technology

    2010-01-01

    compared with keV – MeV radiation. Here we show that synchrotron radiation from cosmic ray protons accelerated in GRBs, delayed by the proton synchrotron... cosmic rays from sources within 100 Mpc for nano-Gauss intergalactic magnetic fields. The total energy requirements in a proton synchrotron model are...component arising from cosmic - ray proton synchrotron radiation explains the delayed onset of the LAT emission. If GRBs accelerate UHECRs, then the

  6. Chemical applications of synchrotron radiation: Workshop report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1989-04-01

    The most recent in a series of topical meetings for Advanced Photon Source user subgroups, the Workshop on Chemical Applications of Synchrotron Radiation (held at Argonne National Laboratory, October 3-4, 1988) dealt with surfaces and kinetics, spectroscopy, small-angle scattering, diffraction, and topography and imaging. The primary objectives were to provide an educational resource for the chemistry community on the scientific research being conducted at existing synchrotron sources and to indicate some of the unique opportunities that will be made available with the Advanced Photon Source. The workshop organizers were also interested in gauging the interest of chemists in the fieldmore » of synchrotron radiation. Interest expressed at the meeting has led to initial steps toward formation of a Chemistry Users Group at the APS. Individual projects are processed separately for the data bases.« less

  7. EXTRAGALACTIC MILLIMETER-WAVE SOURCES IN SOUTH POLE TELESCOPE SURVEY DATA: SOURCE COUNTS, CATALOG, AND STATISTICS FOR AN 87 SQUARE-DEGREE FIELD

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vieira, J. D.; Crawford, T. M.; Switzer, E. R.

    2010-08-10

    We report the results of an 87 deg{sup 2} point-source survey centered at R.A. 5{sup h}30{sup m}, decl. -55{sup 0} taken with the South Pole Telescope at 1.4 and 2.0 mm wavelengths with arcminute resolution and milli-Jansky depth. Based on the ratio of flux in the two bands, we separate the detected sources into two populations, one consistent with synchrotron emission from active galactic nuclei and the other consistent with thermal emission from dust. We present source counts for each population from 11 to 640 mJy at 1.4 mm and from 4.4 to 800 mJy at 2.0 mm. The 2.0more » mm counts are dominated by synchrotron-dominated sources across our reported flux range; the 1.4 mm counts are dominated by synchrotron-dominated sources above {approx}15 mJy and by dust-dominated sources below that flux level. We detect 141 synchrotron-dominated sources and 47 dust-dominated sources at signal-to-noise ratio S/N >4.5 in at least one band. All of the most significantly detected members of the synchrotron-dominated population are associated with sources in previously published radio catalogs. Some of the dust-dominated sources are associated with nearby (z << 1) galaxies whose dust emission is also detected by the Infrared Astronomy Satellite. However, most of the bright, dust-dominated sources have no counterparts in any existing catalogs. We argue that these sources represent the rarest and brightest members of the population commonly referred to as submillimeter galaxies (SMGs). Because these sources are selected at longer wavelengths than in typical SMG surveys, they are expected to have a higher mean redshift distribution and may provide a new window on galaxy formation in the early universe.« less

  8. Variable magnification with Kirkpatrick-Baez optics for synchrotron X-ray microscopy

    DOE PAGES

    Jach, Terrence; Bakulin, Alex S.; Durbin, Stephen M.; ...

    2006-05-01

    In this study, we describe the distinction between the operation of a short focal length x-ray microscope forming a real image with a laboratory source (convergent illumination) and with a highly collimated intense beam from a synchrotron light source (Kohler illumination).

  9. SYNCHROTRON RADIATION, FREE ELECTRON LASER, APPLICATION OF NUCLEAR TECHNOLOGY, ETC.: Study on the characteristics of linac based THz light source

    NASA Astrophysics Data System (ADS)

    Zhu, Xiong-Wei; Wang, Shu-Hong; Chen, Sen-Yu

    2009-10-01

    There are many methods based on linac for THz radiation production. As one of the options for the Beijing Advanced Light, an ERL test facility is proposed for THz radiation. In this test facility, there are 4 kinds of methods to produce THz radiation: coherent synchrotron radiation (CSR), synchrotron radiation (SR), low gain FEL oscillator, and high gain SASE FEL. In this paper, we study the characteristics of the 4 kinds of THz light sources.

  10. The Scale Invariant Synchrotron Jet of Flat Spectrum Radio Quasars

    NASA Astrophysics Data System (ADS)

    Du, L. M.; Bai, J. M.; Xie, Z. H.; Yi, T. F.; Xu, Y. B.; Xue, R.; Wang, X. H.

    2015-06-01

    In this paper, the scale invariance of the synchrotron jet of Flat Spectrum Radio Quasars has been studied using a sample of combined sources from FKM04 and from SDSS DR3 catalogue. Since the research of scale invariance has been focused on sub-Eddington cases that can be fitted onto the fundamental plane, while near-Eddington sources such as FSRQs have not been explicitly studied. The extracted physical properties of synchrotron jet of FSRQs have been shown to be scale invariant using our sample. The results are in good agreement with theoretical expectations of Heinz & Sunyaev (2003). Therefore, the jet synchrotron is shown to be scale independent, regardless of the accretion modes. Results in this article thus lend support to the scale invariant model of the jet synchrotron throughout the mass scale of black hole systems.

  11. Risk taking in adversarial situations: Civilization differences in chess experts.

    PubMed

    Chassy, Philippe; Gobet, Fernand

    2015-08-01

    The projections of experts in politics predict that a new world order will emerge within two decades. Being multipolar, this world will inevitably lead to frictions where civilizations and states will have to decide whether to risk conflict. Very often these decisions are informed if not taken by experts. To estimate risk-taking across civilizations, we examined strategies used in 667,599 chess games played over eleven years by chess experts from 11 different civilizations. We show that some civilizations are more inclined to settle for peace. Similarly, we show that once engaged in the battle, the level of risk taking varies significantly across civilizations, the boldest civilization using the riskiest strategy about 35% more than the most conservative civilization. We discuss which psychological factors might underpin these civilizational differences. Copyright © 2015. Published by Elsevier B.V.

  12. 6th International Conference on Biophysics & Synchrotron Radiation. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moffat, Keith

    1999-08-03

    The 6th International Conference on Biophysics and Synchrotron Rdiation was held at the Advanced Photon Source, Argonne National Laboratory, from August 4-8, 1998, with pre-conference activities on August 3. Over 300 attendees and 65 presenters participated in the conference that was collaboratively hosted by the University of Chicago, Center for Advanced Radiation Sources and the Advanced Photon Source.

  13. National Synchrotron Light Source

    ScienceCinema

    BNL

    2017-12-09

    A tour of Brookhaven's National Synchrotron Light Source (NSLS), hosted by Associate Laboratory Director for Light Sources, Stephen Dierker. The NSLS is one of the world's most widely used scientific research facilities, hosting more than 2,500 guest researchers each year. The NSLS provides intense beams of infrared, ultraviolet, and x-ray light for basic and applied research in physics, chemistry, medicine, geophysics, environmental, and materials sciences.

  14. Time-resolved structural studies at synchrotrons and X-ray free electron lasers: opportunities and challenges

    PubMed Central

    Neutze, Richard; Moffat, Keith

    2012-01-01

    X-ray free electron lasers (XFELs) are potentially revolutionary X-ray sources because of their very short pulse duration, extreme peak brilliance and high spatial coherence, features that distinguish them from today’s synchrotron sources. We review recent time-resolved Laue diffraction and time-resolved wide angle X-ray scattering (WAXS) studies at synchrotron sources, and initial static studies at XFELs. XFELs have the potential to transform the field of time-resolved structural biology, yet many challenges arise in devising and adapting hardware, experimental design and data analysis strategies to exploit their unusual properties. Despite these challenges, we are confident that XFEL sources are poised to shed new light on ultrafast protein reaction dynamics. PMID:23021004

  15. Non-Destructive Trace Element Tomography Using Europe's Brightest Synchrotron Sources (ESRF-Grenoble, DESY-Hamburg) — Towards a Better Understanding of Martian Samples

    NASA Astrophysics Data System (ADS)

    Brenker, F. E.; Vincze, L.; Vekemans, B.; de Poulle, E.

    2018-04-01

    Synchrotron sources are valuable tools to measure the main and trace element content of extraterrestrial samples. The non-destructive measurements will allow to identify important geological processes within the martian mantle and crust.

  16. Prevention and Early Intervention: Individual Differences as Risk Factors for the Mental Health of Children. A Festschrift for Stella Chess and Alexander Thomas.

    ERIC Educational Resources Information Center

    Carey, William B., Ed.; McDevitt, Sean C., Ed.

    This collection of essays, in honor of child psychiatry pioneers Stella Chess and Alexander Thomas, focuses on their idea that important life outcomes are the product of ongoing interactions between a child's behavioral style and the complimentarity or lack of fit of the parenting environment. Following an introduction, the remaining chapters are:…

  17. The Chinese Diaspora: China’s Instrument of Power

    DTIC Science & Technology

    2010-06-01

    Ethnic Chinese, 123. 7 Graeme Dobell, ―China and Taiwan in the South Pacific: Diplomatic Chess versus Pacific Political Rugby ,‖ CSCSD Occasional Paper...Pacific: Diplomatic Chess versus Pacific Political Rugby ‖ (CSCSD Occasional Paper Number 1, The Australian National University, May 2007), 14, http...manufacturing industry," especially in the context of growing protectionist sentiments in the United States and the European Union .46 China has also

  18. The mechanisms and boundary conditions of the Einstellung effect in chess: evidence from eye movements.

    PubMed

    Sheridan, Heather; Reingold, Eyal M

    2013-01-01

    In a wide range of problem-solving settings, the presence of a familiar solution can block the discovery of better solutions (i.e., the Einstellung effect). To investigate this effect, we monitored the eye movements of expert and novice chess players while they solved chess problems that contained a familiar move (i.e., the Einstellung move), as well as an optimal move that was located in a different region of the board. When the Einstellung move was an advantageous (but suboptimal) move, both the expert and novice chess players who chose the Einstellung move continued to look at this move throughout the trial, whereas the subset of expert players who chose the optimal move were able to gradually disengage their attention from the Einstellung move. However, when the Einstellung move was a blunder, all of the experts and the majority of the novices were able to avoid selecting the Einstellung move, and both the experts and novices gradually disengaged their attention from the Einstellung move. These findings shed light on the boundary conditions of the Einstellung effect, and provide convergent evidence for Bilalić, McLeod, & Gobet (2008)'s conclusion that the Einstellung effect operates by biasing attention towards problem features that are associated with the familiar solution rather than the optimal solution.

  19. Practice other than playing games apparently has only a modest role in the development of chess expertise.

    PubMed

    Howard, Robert W

    2013-02-01

    Evidence that chess expertise rests on practice alone mostly comes from studies using a correlational retrospective recall paradigm, which confounds amount of study with number of games played and possible innate talent. Researchers also often use latest performance rating and include participants who play and study little. Study 1 partially replicated such studies with improvements such as use of peak rating and a large, skilled sample. Number of internationally-rated games played was the strongest predictor of peak rating. Total study hours was a significant but weaker predictor. Study 2 controlled for sampling confounds by including only very well-practiced players who had played at least 350 internationally-rated games. Total study hours did not predict rating at 350 games. Study 3 found that the subjective phenomenon of reaching a performance ceiling and undertaking specific practice to get beyond it does occur but does not distinguish between stronger and weaker players. Study 4 found that many players play relatively few internationally-rated games mostly because of other commitments, such as work and education. Extensive study may go along with great interest in and persistence at chess but apparently lacks a major causative role in chess performance level. © 2012 The British Psychological Society.

  20. Evaluating scintillator performance in time-resolved hard X-ray studies at synchrotron light sources.

    PubMed

    Rutherford, Michael E; Chapman, David J; White, Thomas G; Drakopoulos, Michael; Rack, Alexander; Eakins, Daniel E

    2016-05-01

    The short pulse duration, small effective source size and high flux of synchrotron radiation is ideally suited for probing a wide range of transient deformation processes in materials under extreme conditions. In this paper, the challenges of high-resolution time-resolved indirect X-ray detection are reviewed in the context of dynamic synchrotron experiments. In particular, the discussion is targeted at two-dimensional integrating detector methods, such as those focused on dynamic radiography and diffraction experiments. The response of a scintillator to periodic synchrotron X-ray excitation is modelled and validated against experimental data collected at the Diamond Light Source (DLS) and European Synchrotron Radiation Facility (ESRF). An upper bound on the dynamic range accessible in a time-resolved experiment for a given bunch separation is calculated for a range of scintillators. New bunch structures are suggested for DLS and ESRF using the highest-performing commercially available crystal LYSO:Ce, allowing time-resolved experiments with an interframe time of 189 ns and a maximum dynamic range of 98 (6.6 bits).

  1. Evaluating scintillator performance in time-resolved hard X-ray studies at synchrotron light sources

    PubMed Central

    Rutherford, Michael E.; Chapman, David J.; White, Thomas G.; Drakopoulos, Michael; Rack, Alexander; Eakins, Daniel E.

    2016-01-01

    The short pulse duration, small effective source size and high flux of synchrotron radiation is ideally suited for probing a wide range of transient deformation processes in materials under extreme conditions. In this paper, the challenges of high-resolution time-resolved indirect X-ray detection are reviewed in the context of dynamic synchrotron experiments. In particular, the discussion is targeted at two-dimensional integrating detector methods, such as those focused on dynamic radiography and diffraction experiments. The response of a scintillator to periodic synchrotron X-ray excitation is modelled and validated against experimental data collected at the Diamond Light Source (DLS) and European Synchrotron Radiation Facility (ESRF). An upper bound on the dynamic range accessible in a time-resolved experiment for a given bunch separation is calculated for a range of scintillators. New bunch structures are suggested for DLS and ESRF using the highest-performing commercially available crystal LYSO:Ce, allowing time-resolved experiments with an interframe time of 189 ns and a maximum dynamic range of 98 (6.6 bits). PMID:27140147

  2. Photocathodes for High Repetition Rate Light Sources

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ben-Zvi, Ilan

    2014-04-20

    This proposal brought together teams at Brookhaven National Laboratory (BNL), Lawrence Berkeley National Laboratory (LBNL) and Stony Brook University (SBU) to study photocathodes for high repetition rate light sources such as Free Electron Lasers (FEL) and Energy Recovery Linacs (ERL). Below details the Principal Investigators and contact information. Each PI submits separately for a budget through his corresponding institute. The work done under this grant comprises a comprehensive program on critical aspects of the production of the electron beams needed for future user facilities. Our program pioneered in situ and in operando diagnostics for alkali antimonide growth. The focus ismore » on development of photocathodes for high repetition rate Free Electron Lasers (FELs) and Energy Recovery Linacs (ERLs), including testing SRF photoguns, both normal-­conducting and superconducting. Teams from BNL, LBNL and Stony Brook University (SBU) led this research, and coordinated their work over a range of topics. The work leveraged a robust infrastructure of existing facilities and the support was used for carrying out the research at these facilities. The program concentrated in three areas: a) Physics and chemistry of alkali-­antimonide cathodes (BNL – LBNL) b) Development and testing of a diamond amplifier for photocathodes (SBU -­ BNL) c) Tests of both cathodes in superconducting RF photoguns (SBU) and copper RF photoguns (LBNL) Our work made extensive use of synchrotron radiation materials science techniques, such as powder-­ and single-­crystal diffraction, x-­ray fluorescence, EXAFS and variable energy XPS. BNL and LBNL have many complementary facilities at the two light sources associated with these laboratories (NSLS and ALS, respectively); use of these will be a major thrust of our program and bring our understanding of these complex materials to a new level. In addition, CHESS at Cornell will be used to continue seamlessly throughout the NSLS dark period and new diffraction facilities at ALS will be utilized. We also will continue to make use of the excellent analytical facilities at the CNF (BNL) and the Molecular Foundry (LBNL), where we have access to state of the art UHV XPS, SPM, SEM and scanning Auger microscopy.« less

  3. Review of third and next generation synchrotron light sources

    NASA Astrophysics Data System (ADS)

    Bilderback, Donald H.; Elleaume, Pascal; Weckert, Edgar

    2005-05-01

    Synchrotron radiation (SR) is having a very large impact on interdisciplinary science and has been tremendously successful with the arrival of third generation synchrotron x-ray sources. But the revolution in x-ray science is still gaining momentum. Even though new storage rings are currently under construction, even more advanced rings are under design (PETRA III and the ultra high energy x-ray source) and the uses of linacs (energy recovery linac, x-ray free electron laser) can take us further into the future, to provide the unique synchrotron light that is so highly prized for today's studies in science in such fields as materials science, physics, chemistry and biology, for example. All these machines are highly reliant upon the consequences of Einstein's special theory of relativity. The consequences of relativity account for the small opening angle of synchrotron radiation in the forward direction and the increasing mass an electron gains as it is accelerated to high energy. These are familiar results to every synchrotron scientist. In this paper we outline not only the origins of SR but discuss how Einstein's strong character and his intuition and excellence have not only marked the physics of the 20th century but provide the foundation for continuing accelerator developments into the 21st century.

  4. X-Ray Structure determination of the Glycine Cleavage System Protein H of Mycobacterium tuberculosis Using An Inverse Compton Synchrotron X-Ray Source

    PubMed Central

    Abendroth, Jan; McCormick, Michael S.; Edwards, Thomas E.; Staker, Bart; Loewen, Roderick; Gifford, Martin; Rifkin, Jeff; Mayer, Chad; Guo, Wenjin; Zhang, Yang; Myler, Peter; Kelley, Angela; Analau, Erwin; Hewitt, Stephen Nakazawa; Napuli, Alberto J.; Kuhn, Peter; Ruth, Ronald D.; Stewart, Lance J.

    2010-01-01

    Structural genomics discovery projects require ready access to both X-ray and NMR instrumentation which support the collection of experimental data needed to solve large numbers of novel protein structures. The most productive X-ray crystal structure determination laboratories make extensive frequent use of tunable synchrotron X-ray light to solve novel structures by anomalous diffraction methods. This requires that frozen cryo-protected crystals be shipped to large government-run synchrotron facilities for data collection. In an effort to eliminate the need to ship crystals for data collection, we have developed the first laboratory-scale synchrotron light source capable of performing many of the state-of-the-art synchrotron applications in X-ray science. This Compact Light Source is a first-in-class device that uses inverse Compton scattering to generate X-rays of sufficient flux, tunable wavelength and beam size to allow high-resolution X-ray diffraction data collection from protein crystals. We report on benchmarking tests of X-ray diffraction data collection with hen egg white lysozyme, and the successful high-resolution X-ray structure determination of the Glycine cleavage system protein H from Mycobacterium tuberculosis using diffraction data collected with the Compact Light Source X-ray beam. PMID:20364333

  5. Hard X-ray Sources for the Mexican Synchrotron Project

    NASA Astrophysics Data System (ADS)

    Reyes-Herrera, Juan

    2016-10-01

    One of the principal tasks for the design of the Mexican synchrotron was to define the storage ring energy. The main criteria for choosing the energy come from studying the electromagnetic spectrum that can be obtained from the synchrotron, because the energy range of the spectrum that can be obtained will determine the applications available to the users of the future light source. Since there is a public demand of hard X-rays for the experiments in the synchrotron community users from Mexico, in this work we studied the emission spectra from some hard X-ray sources which could be the best options for the parameters of the present Mexican synchrotron design. The calculations of the flux and the brightness for one Bending Magnet and four Insertion Devices are presented; specifically, for a Superconducting Bending Magnet (SBM), a Superconducting Wiggler (SCW), an In Vacuum Short Period Undulator (IV-SPU), a Superconducting Undulator (SCU) and for a Cryogenic Permanent Magnet Undulator (CPMU). Two commonly available synchrotron radiation programs were used for the computation (XOP and SRW). From the results, it can be concluded that the particle beam energy from the current design is enough to have one or more sources of hard X-rays. Furthermore, a wide range of hard X-ray region can be covered by the analyzed sources, and the choice of each type should be based on the specific characteristics of the X-ray beam to perform the experiments at the involved beamline. This work was done within the project Fomix Conacyt-Morelos ”Plan Estrategico para la construccion y operación de un Sincrotron en Morelos” (224392).

  6. Memory and long-range correlations in chess games

    NASA Astrophysics Data System (ADS)

    Schaigorodsky, Ana L.; Perotti, Juan I.; Billoni, Orlando V.

    2014-01-01

    In this paper we report the existence of long-range memory in the opening moves of a chronologically ordered set of chess games using an extensive chess database. We used two mapping rules to build discrete time series and analyzed them using two methods for detecting long-range correlations; rescaled range analysis and detrended fluctuation analysis. We found that long-range memory is related to the level of the players. When the database is filtered according to player levels we found differences in the persistence of the different subsets. For high level players, correlations are stronger at long time scales; whereas in intermediate and low level players they reach the maximum value at shorter time scales. This can be interpreted as a signature of the different strategies used by players with different levels of expertise. These results are robust against the assignation rules and the method employed in the analysis of the time series.

  7. Applications of synchrotron radiation to materials science: Diffraction imaging (topography) and microradiography

    NASA Technical Reports Server (NTRS)

    Kuriyama, Masao

    1988-01-01

    Synchrotron radiation sources are now available throughout the world. The use of hard X-ray radiation from these sources for materials science is described with emphasis on diffraction imaging for material characterization. With the availability of synchrotron radiation, real-time in situ measurements of dynamic microstructural phenomena have been started. This is a new area where traditional application of X-rays has been superseded. Examples are chosen from limited areas and are by no means exhaustive. The new emerging information will, no doubt, have great impact on materials science and engineering.

  8. Support for Synchrotron Access by Environmental Scientists

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Daly, Michael; Madden, Andrew; Palumbo, Anthony

    2006-06-01

    To support ERSP-funded scientists in all aspects of synchrotron-based research at the Advanced Photon Source (APS). This support comes in one or more of the following forms: (1) writing proposals to the APS General User (GU) program, (2) providing time at MRCAT/EnviroCAT beamlines via the membership of the Molecular Environmental Science (MES) Group in MRCAT/EnviroCAT, (3) assistance in experimental design and sample preparation, (4) support at the beamline during the synchrotron experiment, (5) analysis and interpretation of the synchrotron data, and (6) integration of synchrotron experimental results into manuscripts.

  9. Physics of compact nonthermal sources. III - Energetic considerations. [electron synchrotron radiation

    NASA Technical Reports Server (NTRS)

    Burbidge, G. R.; Jones, T. W.; Odell, S. L.

    1974-01-01

    The energy content of the compact incoherent electron-synchrotron sources 3C 84, 3C 120, 3C 273, 3C 279, 3C 454.3, CTA 102, 3C 446, PKS 2134+004, VRO 42.22.01 and OJ 287 is calculated on the assumption that the low-frequency turnovers in the radio spectrum are due to self-absorption and that the electron distribution is isotropic. The dependence of the source parameters on various modifications of the standard assumptions is determined. These involve relativistic motions, alternate explanations for the low-frequency turnover, proton-synchrotron radiation, and distance to the source. The canonical interpretation is found to be accurate in many respects; some of the difficulties and ways of dealing with them are discussed in detail.

  10. CHESS (CgHExpreSS): a comprehensive analysis tool for the analysis of genomic alterations and their effects on the expression profile of the genome.

    PubMed

    Lee, Mikyung; Kim, Yangseok

    2009-12-16

    Genomic alterations frequently occur in many cancer patients and play important mechanistic roles in the pathogenesis of cancer. Furthermore, they can modify the expression level of genes due to altered copy number in the corresponding region of the chromosome. An accumulating body of evidence supports the possibility that strong genome-wide correlation exists between DNA content and gene expression. Therefore, more comprehensive analysis is needed to quantify the relationship between genomic alteration and gene expression. A well-designed bioinformatics tool is essential to perform this kind of integrative analysis. A few programs have already been introduced for integrative analysis. However, there are many limitations in their performance of comprehensive integrated analysis using published software because of limitations in implemented algorithms and visualization modules. To address this issue, we have implemented the Java-based program CHESS to allow integrative analysis of two experimental data sets: genomic alteration and genome-wide expression profile. CHESS is composed of a genomic alteration analysis module and an integrative analysis module. The genomic alteration analysis module detects genomic alteration by applying a threshold based method or SW-ARRAY algorithm and investigates whether the detected alteration is phenotype specific or not. On the other hand, the integrative analysis module measures the genomic alteration's influence on gene expression. It is divided into two separate parts. The first part calculates overall correlation between comparative genomic hybridization ratio and gene expression level by applying following three statistical methods: simple linear regression, Spearman rank correlation and Pearson's correlation. In the second part, CHESS detects the genes that are differentially expressed according to the genomic alteration pattern with three alternative statistical approaches: Student's t-test, Fisher's exact test and Chi square test. By successive operations of two modules, users can clarify how gene expression levels are affected by the phenotype specific genomic alterations. As CHESS was developed in both Java application and web environments, it can be run on a web browser or a local machine. It also supports all experimental platforms if a properly formatted text file is provided to include the chromosomal position of probes and their gene identifiers. CHESS is a user-friendly tool for investigating disease specific genomic alterations and quantitative relationships between those genomic alterations and genome-wide gene expression profiling.

  11. Introducing Synchrotrons Into the Classroom

    ScienceCinema

    Bloch, Ashley; Lanzirotti, Tony

    2018-06-08

    Brookhaven's Introducing Synchrotrons Into the Classroom (InSynC) program gives teachers and their students access to the National Synchrotron Light Source through a competitive proposal process. The first batch of InSynC participants included a group of students from Islip Middle School, who used the massive machine to study the effectiveness of different what filters.

  12. X-ray phase-contrast tomosynthesis of a human ex vivo breast slice with an inverse Compton x-ray source

    NASA Astrophysics Data System (ADS)

    Eggl, E.; Schleede, S.; Bech, M.; Achterhold, K.; Grandl, S.; Sztrókay, A.; Hellerhoff, K.; Mayr, D.; Loewen, R.; Ruth, R. D.; Reiser, M. F.; Pfeiffer, F.

    2016-12-01

    While the performance of conventional x-ray tube sources often suffers from the broad polychromatic spectrum, synchrotrons that could provide highly brilliant x-rays are restricted to large research facilities and impose high investment and maintenance costs. Lately, a new type of compact synchrotron sources has been investigated. These compact light sources (CLS) based on inverse Compton scattering provide quasi-monochromatic hard x-rays. The flux and brilliance yielded by a CLS currently lie between x-ray tube sources and third-generation synchrotrons. The relatively large partially coherent x-ray beam is well suited for the investigation of preclinical applications of grating-based phase-contrast and dark-field imaging. Here we present the first grating-based multimodal tomosynthesis images of a human breast slice acquired at a CLS to investigate the possibilities of improved breast cancer diagnostics.

  13. Signature of inverse Compton emission from blazars

    NASA Astrophysics Data System (ADS)

    Gaur, Haritma; Mohan, Prashanth; Wierzcholska, Alicja; Gu, Minfeng

    2018-01-01

    Blazars are classified into high-, intermediate- and low-energy-peaked sources based on the location of their synchrotron peak. This lies in infra-red/optical to ultra-violet bands for low- and intermediate-peaked blazars. The transition from synchrotron to inverse Compton emission falls in the X-ray bands for such sources. We present the spectral and timing analysis of 14 low- and intermediate-energy-peaked blazars observed with XMM-Newton spanning 31 epochs. Parametric fits to X-ray spectra help constrain the possible location of transition from the high-energy end of the synchrotron to the low-energy end of the inverse Compton emission. In seven sources in our sample, we infer such a transition and constrain the break energy in the range 0.6-10 keV. The Lomb-Scargle periodogram is used to estimate the power spectral density (PSD) shape. It is well described by a power law in a majority of light curves, the index being flatter compared to general expectation from active galactic nuclei, ranging here between 0.01 and 1.12, possibly due to short observation durations resulting in an absence of long-term trends. A toy model involving synchrotron self-Compton and external Compton (EC; disc, broad line region, torus) mechanisms are used to estimate magnetic field strength ≤0.03-0.88 G in sources displaying the energy break and infer a prominent EC contribution. The time-scale for variability being shorter than synchrotron cooling implies steeper PSD slopes which are inferred in these sources.

  14. Skilled Memory and Expertise: Mechanisms of Exceptional Performance

    DTIC Science & Technology

    1988-03-31

    information relevant to events integral to the baseball game . If the scored recall is restricted to relevant information, then similar superiority of experts...moves on a CRT and instructed to play out the game mentally. After about 40 plies into a game , Ericsson and Oliver evaluated PS’s memory for the V _9...another experiment, rather than mentally playing through 30 to 40 moves to reach a middle- game chess position, PS memorized two middle- game chess

  15. Flour pads: devices to improve CHESS fat suppression.

    PubMed

    Moriya, Susumu; Miki, Yukio; Miyati, Tosiaki; Kanagaki, Mitsunori; Yokobayashi, Tsuneo

    2014-01-01

    We compared the suppression of lingering fat signals in chemical shift selective (CHESS) images by pads filled with flour and pads filled with rice in a phantom and human subjects. First, we prepared a phantom by creating an empty space in a mass of lard and filling the space with air, rice, or flour. Then, we obtained MR images of the phantoms in the center of the magnetic field and at a position 8 cm to the left (off-center) to compare lingering fat signals. MR images of the knee were obtained in 10 healthy volunteers using CHESS after placing a polyurethane sponge pillow, rice pad, or flour pad in the popliteal space under the flexed knee. We visually assessed the number of areas with lingering fat signals and the statistical differences among the groups were assessed using Tukey's test. Similarly to rice, flour clearly decreased lingering fat signals in the phantom study. A similar effect was obtained in the off-center images. In the volunteer study, the mean number of areas with lingering fat signals was 2.5 with a sponge pillow, 0.5 with the rice pad, and 0.3 with the flour pad. Those numbers were significantly different using flour pad and rice pad compared with sponge pillow (P < 0.001). No significant differences were seen between flour pads and rice pads (P = 0.662). Flour pads can suppress lingering fat signals in CHESS images.

  16. Negative ion source development at the cooler synchrotron COSY/Jülich

    NASA Astrophysics Data System (ADS)

    Felden, O.; Gebel, R.; Maier, R.; Prasuhn, D.

    2013-02-01

    The Nuclear Physics Institute at the Forschungszentrum Jülich, a member of the Helmholtz Association, conducts experimental and theoretical basic research in the field of hadron, particle, and nuclear physics. It operates the cooler synchrotron COSY, an accelerator and storage ring, which provides unpolarized and polarized proton and deuteron beams with beam momenta of up to 3.7 GeV/c. Main activities of the accelerator division are the design and construction of the high energy storage ring HESR, a synchrotron and part of the international FAIR project, and the operation and development of COSY with injector cyclotron and ion sources. Filament driven volume sources and a charge exchange colliding beams source, based on a nuclear polarized atomic beam source, provide unpolarized and polarized H- or D- routinely for more than 6500 hours/year. Within the Helmholtz Association's initiative Accelerator Research and Development, ARD, the existing sources at COSY, as well as new sources for future programs, are investigated and developed. The paper reports about these plans, improved pulsed beams from the volume sources and the preparation of a source for the ELENA project at CERN.

  17. National Synchrotron Light Source II

    ScienceCinema

    Hill, John; Dooryhee, Eric; Wilkins, Stuart; Miller, Lisa; Chu, Yong

    2018-01-16

    NSLS-II is a synchrotron light source helping researchers explore solutions to the grand energy challenges faced by the nation, and open up new regimes of scientific discovery that will pave the way to discoveries in physics, chemistry, and biology — advances that will ultimately enhance national security and help drive the development of abundant, safe, and clean energy technologies.

  18. Synchrotron Radiation from Outer Space and the Chandra X-Ray Observatory

    NASA Technical Reports Server (NTRS)

    Weisskopf, M. C.

    2006-01-01

    The universe provides numerous extremely interesting astrophysical sources of synchrotron X radiation. The Chandra X-ray Observatory and other X-ray missions provide powerful probes of these and other cosmic X-ray sources. Chandra is the X-ray component of NASA's Great Observatory Program which also includes the Hubble Space telescope, the Spitzer Infrared Telescope Facility, and the now defunct Compton Gamma-Ray Observatory. The Chandra X-Ray Observatory provides the best angular resolution (sub-arcsecond) of any previous, current, or planned (for the foreseeable near future) space-based X-ray instrumentation. We present here a brief overview of the technical capability of this X-Ray observatory and some of the remarkable discoveries involving cosmic synchrotron sources.

  19. Pure-type superconducting permanent-magnet undulator.

    PubMed

    Tanaka, Takashi; Tsuru, Rieko; Kitamura, Hideo

    2005-07-01

    A novel synchrotron radiation source is proposed that utilizes bulk-type high-temperature superconductors (HTSCs) as permanent magnets (PMs) by in situ magnetization. Arrays of HTSC blocks magnetized by external magnetic fields are placed below and above the electron path instead of conventional PMs, generating a periodic magnetic field with an offset. Two methods are presented to magnetize the HTSCs and eliminate the field offset, enabling the HTSC arrays to work as a synchrotron radiation source. An analytical formula to calculate the peak field achieved in a device based on this scheme is derived in a two-dimensional form for comparison with synchrotron radiation sources using conventional PMs. Experiments were performed to demonstrate the principle of the proposed scheme and the results have been found to be very promising.

  20. The assembly, calibration, and preliminary results from the Colorado high-resolution Echelle stellar spectrograph (CHESS)

    NASA Astrophysics Data System (ADS)

    Hoadley, Keri; France, Kevin; Nell, Nicholas; Kane, Robert; Schultz, Ted; Beasley, Matthew; Green, James; Kulow, Jen; Kersgaard, Eliot; Fleming, Brian

    2014-07-01

    The Colorado High-resolution Echelle Stellar Spectrograph (CHESS) is a far ultraviolet (FUV) rocket-borne experiment designed to study the atomic-to-molecular transitions within translucent interstellar clouds. CHESS is an objective echelle spectrograph operating at f/12.4 and resolving power of 120,000 over a band pass of 100 - 160 nm. The echelle flight grating is the product of a research and development project with LightSmyth Inc. and was coated at Goddard Space Flight Center (GSFC) with Al+LiF. It has an empirically-determined groove density of 71.67 grooves/mm. At the Center for Astrophysics and Space Astronomy (CASA) at the University of Colorado (CU), we measured the efficiencies of the peak and adjacent dispersion orders throughout the 90 - 165 nm band pass to characterize the behavior of the grating for pre-flight calibrations and to assess the scattered-light behavior. The crossdispersing grating, developed and ruled by Horiba Jobin-Yvon, is a holographically-ruled, low line density (351 grooves/mm), powered optic with a toroidal surface curvature. The CHESS cross-disperser was also coated at GSFC; Cr+Al+LiF was deposited to enhance far-UV efficiency. Results from final efficiency and reflectivity measurements of both optics are presented. We utilize a cross-strip anode microchannel plate (MCP) detector built by Sensor Sciences to achieve high resolution (25 μm spatial resolution) and data collection rates (~ 106 photons/second) over a large format (40mm round, digitized to 8k x 8k) for the first time in an astronomical sounding rocket flight. The CHESS instrument was successfully launched from White Sands Missile Range on 24 May 2014. We present pre-flight sensitivity, effective area calculations, lab spectra and calibration results, and touch on first results and post-flight calibration plans.

  1. Video-based beam position monitoring at CHESS

    NASA Astrophysics Data System (ADS)

    Revesz, Peter; Pauling, Alan; Krawczyk, Thomas; Kelly, Kevin J.

    2012-10-01

    CHESS has pioneered the development of X-ray Video Beam Position Monitors (VBPMs). Unlike traditional photoelectron beam position monitors that rely on photoelectrons generated by the fringe edges of the X-ray beam, with VBPMs we collect information from the whole cross-section of the X-ray beam. VBPMs can also give real-time shape/size information. We have developed three types of VBPMs: (1) VBPMs based on helium luminescence from the intense white X-ray beam. In this case the CCD camera is viewing the luminescence from the side. (2) VBPMs based on luminescence of a thin (~50 micron) CVD diamond sheet as the white beam passes through it. The CCD camera is placed outside the beam line vacuum and views the diamond fluorescence through a viewport. (3) Scatter-based VBPMs. In this case the white X-ray beam passes through a thin graphite filter or Be window. The scattered X-rays create an image of the beam's footprint on an X-ray sensitive fluorescent screen using a slit placed outside the beam line vacuum. For all VBPMs we use relatively inexpensive 1.3 Mega-pixel CCD cameras connected via USB to a Windows host for image acquisition and analysis. The VBPM host computers are networked and provide live images of the beam and streams of data about the beam position, profile and intensity to CHESS's signal logging system and to the CHESS operator. The operational use of VBPMs showed great advantage over the traditional BPMs by providing direct visual input for the CHESS operator. The VBPM precision in most cases is on the order of ~0.1 micron. On the down side, the data acquisition frequency (50-1000ms) is inferior to the photoelectron based BPMs. In the future with the use of more expensive fast cameras we will be able create VBPMs working in the few hundreds Hz scale.

  2. Chemical Crystallography at the Advanced Light Source

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McCormick, Laura; Giordano, Nico; Teat, Simon

    Chemical crystallography at synchrotrons was pioneered at the Daresbury SRS station 9.8. The chemical crystallography beamlines at the Advanced Light Source seek to follow that example, with orders of magnitude more flux than a lab source, and various in situ experiments. This article thus attempts to answer why a chemist would require synchrotron X-rays, to describe the techniques available at the ALS chemical crystallography beamlines, and place the current facilities in a historical context.

  3. Chemical Crystallography at the Advanced Light Source

    DOE PAGES

    McCormick, Laura; Giordano, Nico; Teat, Simon; ...

    2017-12-18

    Chemical crystallography at synchrotrons was pioneered at the Daresbury SRS station 9.8. The chemical crystallography beamlines at the Advanced Light Source seek to follow that example, with orders of magnitude more flux than a lab source, and various in situ experiments. This article thus attempts to answer why a chemist would require synchrotron X-rays, to describe the techniques available at the ALS chemical crystallography beamlines, and place the current facilities in a historical context.

  4. Status of the Siberian synchrotron radiation center

    NASA Astrophysics Data System (ADS)

    Ancharov, A. I.; Baryshev, V. B.; Chernov, V. A.; Gentselev, A. N.; Goldenberg, B. G.; Kochubei, D. I.; Korchuganov, V. N.; Kulipanov, G. N.; Kuzin, M. V.; Levichev, E. B.; Mezentsev, N. A.; Mishnev, S. I.; Nikolenko, A. D.; Pindyurin, V. F.; Sheromov, M. A.; Tolochko, B. P.; Sharafutdinov, M. R.; Shmakov, A. N.; Vinokurov, N. A.; Vobly, P. D.; Zolotarev, K. V.

    2005-05-01

    Synchrotron radiation (SR) experiments at the Budker Institute of Nuclear Physics had been started in 1973, and from 1981 the Siberian Synchrotron Radiation Center (SSRC) had an official status as Research Center of the Russian Academy of Sciences. SSRC is the research center, which is open and free of tax for the research teams from Russia and abroad. In this report some technical information about the storage rings—SR sources of the Budker INP, the main directions of activity of SSRC, experimental stations, experimental works and users—is given. Development of the free electron lasers, new SR sources and insertion devices is described.

  5. Chess players' fame versus their merit.

    PubMed

    Simkin, M V; Roychowdhury, V P

    2015-12-12

    We investigate a pool of international chess title holders born between 1901 and 1943. Using Elo ratings, we compute for every player his expected score in a game with a randomly selected player from the pool. We use this figure as the player's merit. We measure players' fame as the number of Google hits. The correlation between fame and merit is 0.38. At the same time, the correlation between the logarithm of fame and merit is 0.61. This suggests that fame grows exponentially with merit.

  6. Chess games: a model for RNA based computation.

    PubMed

    Cukras, A R; Faulhammer, D; Lipton, R J; Landweber, L F

    1999-10-01

    Here we develop the theory of RNA computing and a method for solving the 'knight problem' as an instance of a satisfiability (SAT) problem. Using only biological molecules and enzymes as tools, we developed an algorithm for solving the knight problem (3 x 3 chess board) using a 10-bit combinatorial pool and sequential RNase H digestions. The results of preliminary experiments presented here reveal that the protocol recovers far more correct solutions than expected at random, but the persistence of errors still presents the greatest challenge.

  7. SYNCHROTRON HEATING BY A FAST RADIO BURST IN A SELF-ABSORBED SYNCHROTRON NEBULA AND ITS OBSERVATIONAL SIGNATURE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yang, Yuan-Pei; Dai, Zi-Gao; Zhang, Bing, E-mail: zhang@physics.unlv.edu

    Fast radio bursts (FRBs) are mysterious transient sources. If extragalactic, as suggested by their relative large dispersion measures, their brightness temperatures must be extremely high. Some FRB models (e.g., young pulsar model, magnetar giant flare model, or supra-massive neutron star collapse model) suggest that they may be associated with a synchrotron nebula. Here we study a synchrotron-heating process by an FRB in a self-absorbed synchrotron nebula. If the FRB frequency is below the synchrotron self-absorption frequency of the nebula, electrons in the nebula would absorb FRB photons, leading to a harder electron spectrum and enhanced self-absorbed synchrotron emission. In themore » meantime, the FRB flux is absorbed by the nebula electrons. We calculate the spectra of FRB-heated synchrotron nebulae, and show that the nebula spectra would show a significant hump in several decades near the self-absorption frequency. Identifying such a spectral feature would reveal an embedded FRB in a synchrotron nebula.« less

  8. Nsls-II Boster

    NASA Astrophysics Data System (ADS)

    Gurov, S. M.; Akimov, A. V.; Akimov, V. E.; Anashin, V. V.; Anchugov, O. V.; Baranov, G. N.; Batrakov, A. M.; Belikov, O. V.; Bekhtenev, E. A.; Blum, E.; Bulatov, A. V.; Burenkov, D. B.; Cheblakov, P. B.; Chernyakin, A. D.; Cheskidov, V. G.; Churkin, I. N.; Davidsavier, M.; Derbenev, A. A.; Erokhin, A. I.; Fliller, R. P.; Fulkerson, M.; Gorchakov, K. M.; Ganetis, G.; Gao, F.; Gurov, D. S.; Hseuh, H.; Hu, Y.; Johanson, M.; Kadyrov, R. A.; Karnaev, S. E.; Karpov, G. V.; Kiselev, V. A.; Kobets, V. V.; Konstantinov, V. M.; Kolmogorov, V. V.; Korepanov, A. A.; Kramer, S.; Krasnov, A. A.; Kremnev, A. A.; Kuper, E. A.; Kuzminykh, V. S.; Levichev, E. B.; Li, Y.; Long, J. De; Makeev, A. V.; Mamkin, V. R.; Medvedko, A. S.; Meshkov, O. I.; Nefedov, N. B.; Neyfeld, V. V.; Okunev, I. N.; Ozaki, S.; Padrazo, D.; Petrov, V. V.; Petrichenkov, M. V.; Philipchenko, A. V.; Polyansky, A. V.; Pureskin, D. N.; Rakhimov, A. R.; Rose, J.; Ruvinskiy, S. I.; Rybitskaya, T. V.; Sazonov, N. V.; Schegolev, L. M.; Semenov, A. M.; Semenov, E. P.; Senkov, D. V.; Serdakov, L. E.; Serednyakov, S. S.; Shaftan, T. V.; Sharma, S.; Shichkov, D. S.; Shiyankov, S. V.; Shvedov, D. A.; Simonov, E. A.; Singh, O.; Sinyatkin, S. V.; Smaluk, V. V.; Sukhanov, A. V.; Tian, Y.; Tsukanova, L. A.; Vakhrushev, R. V.; Vobly, P. D.; Utkin, A. V.; Wang, G.; Wahl, W.; Willeke, F.; Yaminov, K. R.; Yong, H.; Zhuravlev, A.; Zuhoski, P.

    The National Synchrotron Light Source II is a third generation light source, which was constructed at Brookhaven National Laboratory. This project includes a highly-optimized 3 GeV electron storage ring, linac preinjector, and full-energy synchrotron injector. Budker Institute of Nuclear Physics built and delivered the booster for NSLS-II. The commissioning of the booster was successfully completed. This paper reviews fulfilled work by participants.

  9. Main functions, recent updates, and applications of Synchrotron Radiation Workshop code

    NASA Astrophysics Data System (ADS)

    Chubar, Oleg; Rakitin, Maksim; Chen-Wiegart, Yu-Chen Karen; Chu, Yong S.; Fluerasu, Andrei; Hidas, Dean; Wiegart, Lutz

    2017-08-01

    The paper presents an overview of the main functions and new application examples of the "Synchrotron Radiation Workshop" (SRW) code. SRW supports high-accuracy calculations of different types of synchrotron radiation, and simulations of propagation of fully-coherent radiation wavefronts, partially-coherent radiation from a finite-emittance electron beam of a storage ring source, and time-/frequency-dependent radiation pulses of a free-electron laser, through X-ray optical elements of a beamline. An extended library of physical-optics "propagators" for different types of reflective, refractive and diffractive X-ray optics with its typical imperfections, implemented in SRW, enable simulation of practically any X-ray beamline in a modern light source facility. The high accuracy of calculation methods used in SRW allows for multiple applications of this code, not only in the area of development of instruments and beamlines for new light source facilities, but also in areas such as electron beam diagnostics, commissioning and performance benchmarking of insertion devices and individual X-ray optical elements of beamlines. Applications of SRW in these areas, facilitating development and advanced commissioning of beamlines at the National Synchrotron Light Source II (NSLS-II), are described.

  10. The tell-tale heart: heart rate fluctuations index objective and subjective events during a game of chess.

    PubMed

    Leone, María J; Petroni, Agustín; Fernandez Slezak, Diego; Sigman, Mariano

    2012-01-01

    During a decision-making process, the body changes. These somatic changes have been related to specific cognitive events and also have been postulated to assist decision-making indexing possible outcomes of different options. We used chess to analyze heart rate (HR) modulations on specific cognitive events. In a chess game, players have a limited time-budget to make about 40 moves (decisions) that can be objectively evaluated and retrospectively assigned to specific subjectively perceived events, such as setting a goal and the process to reach a known goal. We show that HR signals events: it predicts the conception of a plan, the concrete analysis of variations or the likelihood to blunder by fluctuations before to the move, and it reflects reactions, such as a blunder made by the opponent, by fluctuations subsequent to the move. Our data demonstrate that even if HR constitutes a relatively broad marker integrating a myriad of physiological variables, its dynamic is rich enough to reveal relevant episodes of inner thought.

  11. Reciprocal Space Mapping of Macromolecular Crystals in the Home Laboratory

    NASA Technical Reports Server (NTRS)

    Snell, Edward H.; Fewster, P. F.; Andrew, Norman; Boggon, T. J.; Judge, Russell A.; Pusey, Marc A.

    1999-01-01

    Reciprocal space mapping techniques are used widely by the materials science community to provide physical information about their crystal samples. We have used similar methods at synchrotron sources to look at the quality of macromolecular crystals produced both on the ground and under microgravity conditions. The limited nature of synchrotron time has led us to explore the use of a high resolution materials research diffractometer to perform similar measurements in the home laboratory. Although the available intensity is much reduced due to the beam conditioning necessary for high reciprocal space resolution, lower resolution data can be collected in the same detail as the synchrotron source. Experiments can be optimized at home to make most benefit from the synchrotron time available. Preliminary results including information on the mosaicity and the internal strains from reciprocal space maps will be presented.

  12. Synchrotron X-Ray Diffraction Analysis of Meteorites in Thin Section: Preliminary Results

    NASA Technical Reports Server (NTRS)

    Treiman, A. H.; Lanzirotti, A.; Xirouchakis, D.

    2004-01-01

    X-ray diffraction is the pre-eminent technique for mineral identification and structure determination, but is difficult to apply to grains in thin section, the standard meteorite preparation. Bright focused X-ray beams from synchrotrons have been used extensively in mineralogy and have been applied to extraterrestrial particles. The intensity and small spot size achievable in synchrotron X-ray beams makes them useful for study of materials in thin sections. Here, we describe Synchrotron X-ray Diffraction (SXRD) in thin section as done at the National Synchrotron Light Source, and cite examples of its value for studies of meteorites in thin section.

  13. Efficacy of chess training for the treatment of ADHD: A prospective, open label study.

    PubMed

    Blasco-Fontecilla, Hilario; Gonzalez-Perez, Marisa; Garcia-Lopez, Raquel; Poza-Cano, Belen; Perez-Moreno, Maria Rosario; de Leon-Martinez, Victoria; Otero-Perez, Jose

    2016-01-01

    To examine the effectiveness of playing chess as a treatment option for children with ADHD. Parents of 44 children ages 6 to 17 with a primary diagnosis of ADHD consented to take part in the study. Parents completed the Spanish version of the Swanson, Nolan and Pelham Scale for parents (SNAP-IV) and the Abbreviated Conner's Rating Scales for parents (CPRS-HI) prior to an 11-week chess-training program. We used a paired t-test to compare pre- and post-intervention outcomes, and Cohen-d calculations to measure the magnitude of the effect. The statistical significance was set at P<.05. Children with ADHD improved in both the SNAP-IV (t=6.23; degrees of freedom (df)=41; P<.001) and the CPRS-HI (t=5.39; df=33; P<.001). Our results suggest a large effect in decreasing the severity of ADHD as measured by the SNAP-IV (d=0.85) and the CPRS-HI (d=0.85). Furthermore, we found a correlation between intelligence quotient and SNAP-IV improvement (P<.05). The results of our pilot study should be interpreted with caution. This pilot project highlights the importance of carrying out larger studies with a case-control design. If our results are replicated in better designed studies, playing chess could be included within the multimodal treatment of ADHD. Copyright © 2014 SEP y SEPB. Published by Elsevier España. All rights reserved.

  14. Real time observation of mouse fetal skeleton using a high resolution X-ray synchrotron

    PubMed Central

    Chang, Dong Woo; Kim, Bora; Shin, Jae Hoon; Yun, Young Min; Je, Jung Ho; Hwu, Yeu kuang; Yoon, Jung Hee

    2011-01-01

    The X-ray synchrotron is quite different from conventional radiation sources. This technique may expand the capabilities of conventional radiology and be applied in novel manners for special cases. To evaluate the usefulness of X-ray synchrotron radiation systems for real time observations, mouse fetal skeleton development was monitored with a high resolution X-ray synchrotron. A non-monochromatized X-ray synchrotron (white beam, 5C1 beamline) was employed to observe the skeleton of mice under anesthesia at embryonic day (E)12, E14, E15, and E18. At the same time, conventional radiography and mammography were used to compare with X-ray synchrotron. After synchrotron radiation, each mouse was sacrificed and stained with Alizarin red S and Alcian blue to observe bony structures. Synchrotron radiation enabled us to view the mouse fetal skeleton beginning at gestation. Synchrotron radiation systems facilitate real time observations of the fetal skeleton with greater accuracy and magnification compared to mammography and conventional radiography. Our results show that X-ray synchrotron systems can be used to observe the fine structures of internal organs at high magnification. PMID:21586868

  15. Influence of synchrotron self-absorption on 21-cm experiments

    NASA Astrophysics Data System (ADS)

    Zheng, Qian; Wu, Xiang-Ping; Gu, Jun-Hua; Wang, Jingying; Xu, Haiguang

    2012-08-01

    The presence of spectral curvature resulting from the synchrotron self-absorption of extragalactic radio sources could break down the spectral smoothness feature. This leads to the premise that the bright radio foreground can be successfully removed in 21-cm experiments that search for the epoch of reionization (EoR). We present a quantitative estimate of the effect of the spectral curvature resulting from the synchrotron self-absorption of extragalactic radio sources on the measurement of the angular power spectrum of the low-frequency sky. We incorporate a phenomenological model, which is characterized by the fraction (f) of radio sources with turnover frequencies in the range of 100-1000 MHz and by a broken power law for the spectral transition around the turnover frequencies νm, into simulated radio sources over a small sky area of 10° × 10°. We compare statistically the changes in their residual maps with and without the inclusion of the synchrotron self-absorption of extragalactic radio sources after the bright sources of S150 MHz ≥100 mJy are excised. Furthermore, the best-fitting polynomials in the frequency domain on each pixel are subtracted. It has been shown that the effect of synchrotron self-absorption on the detection of the EoR depends sensitively on the spectral profiles of the radio sources around the turnover frequencies νm. A hard transition model, described by the broken power law with the turnover of spectral index at νm, would leave pronounced imprints on the residual background and would therefore cause serious confusion with the cosmic EoR signal. However, the spectral signatures on the angular power spectrum of the extragalactic foreground, generated by a soft transition model in which the rising and falling power laws of the spectral distribution around νm are connected through a smooth transition spanning ≥200 MHz in a characteristic width, can be fitted and consequently subtracted by the use of polynomials to an acceptable degree (δT < 1 mK). As this latter scenario seems to be favoured in both theoretical expectations and radio spectral observations, we conclude that the contamination of extragalactic radio sources by synchrotron self-absorption in 21-cm experiments is probably very minor.

  16. Low-pressure Structural Modification of Aluminum Hydride

    DTIC Science & Technology

    2011-02-01

    Acknowledgments Use of the National Synchrotron Light Source (NSLS), Brookhaven National Laboratory ( BNL ) was supported by the U.S. Department of Energy...National Synchrotron Light Source (NSLS) of Brookhaven National Laboratory ( BNL ). The spectral resolution of ±4 cm–1 was used for all IR measurements...12 List of Symbols, Abbreviations, and Acronyms Al aluminum AlH3 aluminum hydride BNL Brookhaven National Laboratory EOS equation of

  17. 1994 Activity Report, National Synchrotron Light Source. Annual report, October 1, 1993-September 30, 1994

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rothman, E.Z.

    1995-05-01

    This report is a summary of activities carried out at the National Synchrotron Light Source during 1994. It consists of sections which summarize the work carried out in differing scientific disciplines, meetings and workshops, operations experience of the facility, projects undertaken for upgrades, administrative reports, and collections of abstracts and publications generated from work done at the facility.

  18. Synchrotron Radiation Workshop (SRW)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chubar, O.; Elleaume, P.

    2013-03-01

    "Synchrotron Radiation Workshop" (SRW) is a physical optics computer code for calculation of detailed characteristics of Synchrotron Radiation (SR) generated by relativistic electrons in magnetic fields of arbitrary configuration and for simulation of the radiation wavefront propagation through optical systems of beamlines. Frequency-domain near-field methods are used for the SR calculation, and the Fourier-optics based approach is generally used for the wavefront propagation simulation. The code enables both fully- and partially-coherent radiation propagation simulations in steady-state and in frequency-/time-dependent regimes. With these features, the code has already proven its utility for a large number of applications in infrared, UV, softmore » and hard X-ray spectral range, in such important areas as analysis of spectral performances of new synchrotron radiation sources, optimization of user beamlines, development of new optical elements, source and beamline diagnostics, and even complete simulation of SR based experiments. Besides the SR applications, the code can be efficiently used for various simulations involving conventional lasers and other sources. SRW versions interfaced to Python and to IGOR Pro (WaveMetrics), as well as cross-platform library with C API, are available.« less

  19. MICROANALYSIS OF MATERIALS USING SYNCHROTRON RADIATION.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    JONES,K.W.; FENG,H.

    2000-12-01

    High intensity synchrotron radiation produces photons with wavelengths that extend from the infrared to hard x rays with energies of hundreds of keV with uniquely high photon intensities that can be used to determine the composition and properties of materials using a variety of techniques. Most of these techniques represent extensions of earlier work performed with ordinary tube-type x-ray sources. The properties of the synchrotron source such as the continuous range of energy, high degree of photon polarization, pulsed beams, and photon flux many orders of magnitude higher than from x-ray tubes have made possible major advances in the possiblemore » chemical applications. We describe here ways that materials analyses can be made using the high intensity beams for measurements with small beam sizes and/or high detection sensitivity. The relevant characteristics of synchrotron x-ray sources are briefly summarized to give an idea of the x-ray parameters to be exploited. The experimental techniques considered include x-ray fluorescence, absorption, and diffraction. Examples of typical experimental apparatus used in these experiments are considered together with descriptions of actual applications.« less

  20. Perspectives of synchrotron radiation sources with superconductivity

    NASA Astrophysics Data System (ADS)

    Tanaka, Takashi

    2007-10-01

    The synchrotron radiation source is a magnetic device to generate a periodic magnetic field where a relativistic electron moves along a periodic trajectory and emits light called synchrotron radiation (SR), which has been used as a scientific probe for many years in various fields. Although permanent magnets (PMs) are usually used to generate the magnetic field in the SR source because of their cost-effectiveness and availability, a large number of SR sources with superconductors have been constructed for special uses, i.e., to obtain a strong magnetic field over 3 T, which cannot be achieved by using PMs alone. Most of these SR sources are composed of electromagnets with superconducting coils made of NbTi as in commercially available superconducting magnets. For stronger magnetic field, research on application of Nb3Sn is in progress. On the other hand, utilization of high Tc superconducting bulk magnets has been recently proposed and R&Ds toward realization are being carried out. This paper reviews the currents status of the SR sources with superconductivity and describes the future perspectives.

  1. On the Nature of Design

    NASA Astrophysics Data System (ADS)

    Valverde, Sergi; Solé, Ricard V.

    At the attention of scientist, philosophers and layman alike. It was so extraordinary in fact that even today we are fascinated by it and by the no less uncommon people who got involved. The subject of this story was an amazing machine, more precisely an automaton. Known as the Turk, it was a mechanical chess player, made of wood and dressed in a Turkish-like costume (see Fig. 1). It played chess with Napoleon, inspired Charles Babbage and moved the great Edgar Allan Poe to write a critical essay about the nature of the automaton [1].

  2. Report on Workshop on Research in Experimental Computer Science Held in Palo Alto, California on 16-18 October 1991

    DTIC Science & Technology

    1992-06-01

    HiTech was the highest ranked chess ma- chine between 1985 and 1988, and the three things that were key to HiTech’s success ’D. S. Johnson and C. C...colleagues to help him understand anomalies. Hans Berliner discussed the HiTech chess machine. This was a small project that began with a new idea of one of...light. 4. Proposals to do experimental research should have detailed sections on the method- ology and the criteria that would constitute success of

  3. The angular power spectrum measurement of the Galactic synchrotron emission using the TGSS survey

    NASA Astrophysics Data System (ADS)

    Choudhuri, Samir; Bharadwaj, Somnath; Ali, Sk. Saiyad; Roy, Nirupam; Intema, H. T.; Ghosh, Abhik

    2018-05-01

    Characterizing the diffuse Galactic synchrotron emission (DGSE) at arcminute angular scales is needed to remove this foregrounds in cosmological 21-cm measurements. Here, we present the angular power spectrum (Cl) measurement of the diffuse Galactic synchrotron emission using two fields observed by the TIFR GMRT Sky Survey (TGSS). We apply 2D Tapered Gridded Estimator (TGE) to estimate the Cl from the visibilities. We find that the residual data after subtracting the point sources is likely dominated by the diffuse Galactic synchrotron radiation across the angular multipole range 240 <= l <~ 500. We fit a power law to the measured Cl over this l range. We find that the slopes in both fields are consistent with earlier measurements. For the second field, however, we interpret the measured Cl as an upper limit for the DGSE as there is an indication of a significant residual point source contribution.

  4. Optimizing a synchrotron based x-ray lithography system for IC manufacturing

    NASA Astrophysics Data System (ADS)

    Kovacs, Stephen; Speiser, Kenneth; Thaw, Winston; Heese, Richard N.

    1990-05-01

    The electron storage ring is a realistic solution as a radiation source for production grade, industrial X-ray lithography system. Today several large scale plans are in motion to design and implement synchrotron storage rings of different types for this purpose in the USA and abroad. Most of the scientific and technological problems related to the physics, design and manufacturing engineering, and commissioning of these systems for microlithography have been resolved or are under extensive study. However, investigation on issues connected to application of Synchrotron Orbit Radiation (SOR ) in chip production environment has been somewhat neglected. In this paper we have filled this gap pointing out direct effects of some basic synchrotron design parameters and associated subsystems (injector, X-ray beam line) on the operation and cost of lithography in production. The following factors were considered: synchrotron configuration, injection energy, beam intensity variability, number of beam lines and wafer exposure concept. A cost model has been worked out and applied to three different X-ray Lithography Source (XLS) systems. The results of these applications are compared and conclusions drawn.

  5. Single-bunch synchrotron shutter

    DOEpatents

    Norris, James R.; Tang, Jau-Huei; Chen, Lin; Thurnauer, Marion

    1993-01-01

    An apparatus for selecting a single synchrotron pulse from the millions of pulses provided per second from a synchrotron source includes a rotating spindle located in the path of the synchrotron pulses. The spindle has multiple faces of a highly reflective surface, and having a frequency of rotation f. A shutter is spaced from the spindle by a radius r, and has an open position and a closed position. The pulses from the synchrotron are reflected off the spindle to the shutter such that the speed s of the pulses at the shutter is governed by: s=4.times..pi..times.r.times.f. such that a single pulse is selected for transmission through an open position of the shutter.

  6. Development of Partially-Coherent Wavefront Propagation Simulation Methods for 3rd and 4th Generation Synchrotron Radiation Sources.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chubar O.; Berman, L; Chu, Y.S.

    2012-04-04

    Partially-coherent wavefront propagation calculations have proven to be feasible and very beneficial in the design of beamlines for 3rd and 4th generation Synchrotron Radiation (SR) sources. These types of calculations use the framework of classical electrodynamics for the description, on the same accuracy level, of the emission by relativistic electrons moving in magnetic fields of accelerators, and the propagation of the emitted radiation wavefronts through beamline optical elements. This enables accurate prediction of performance characteristics for beamlines exploiting high SR brightness and/or high spectral flux. Detailed analysis of radiation degree of coherence, offered by the partially-coherent wavefront propagation method, ismore » of paramount importance for modern storage-ring based SR sources, which, thanks to extremely small sub-nanometer-level electron beam emittances, produce substantial portions of coherent flux in X-ray spectral range. We describe the general approach to partially-coherent SR wavefront propagation simulations and present examples of such simulations performed using 'Synchrotron Radiation Workshop' (SRW) code for the parameters of hard X-ray undulator based beamlines at the National Synchrotron Light Source II (NSLS-II), Brookhaven National Laboratory. These examples illustrate general characteristics of partially-coherent undulator radiation beams in low-emittance SR sources, and demonstrate advantages of applying high-accuracy physical-optics simulations to the optimization and performance prediction of X-ray optical beamlines in these new sources.« less

  7. Fundamentals of Coherent Synchrotron Radiation in Storage Rings

    NASA Astrophysics Data System (ADS)

    Sannibale, F.; Byrd, J. M.; Loftsdottir, A.; Martin, M. C.; Venturini, M.

    2004-05-01

    We present the fundamental concepts for producing stable broadband coherent synchrotron radiation (CSR) in the terahertz frequency region in an electron storage ring. The analysis includes distortion of bunch shape from the synchrotron radiation (SR), enhancing higher frequency coherent emission and limits to stable emission due to a microbunching instability excited by the SR. We use these concepts to optimize the performance of a source for CSR emission.

  8. Observation of Multi-bunch Interference with Coherent Synchrotron Radiation

    NASA Astrophysics Data System (ADS)

    Billinghurst, B. E.; May, T.; Bergstrom, J.; DeJong, M.; Dallin, L.

    2010-02-01

    The observation of Multi-bunch interference with coherent synchrotron radiation at the Canadian Light Source is discussed along with the possibility that some of the spectral features are driven by the radiation impedance of the vacuum chamber.

  9. Local reconstruction in computed tomography of diffraction enhanced imaging

    NASA Astrophysics Data System (ADS)

    Huang, Zhi-Feng; Zhang, Li; Kang, Ke-Jun; Chen, Zhi-Qiang; Zhu, Pei-Ping; Yuan, Qing-Xi; Huang, Wan-Xia

    2007-07-01

    Computed tomography of diffraction enhanced imaging (DEI-CT) based on synchrotron radiation source has extremely high sensitivity of weakly absorbing low-Z samples in medical and biological fields. The authors propose a modified backprojection filtration(BPF)-type algorithm based on PI-line segments to reconstruct region of interest from truncated refraction-angle projection data in DEI-CT. The distribution of refractive index decrement in the sample can be directly estimated from its reconstruction images, which has been proved by experiments at the Beijing Synchrotron Radiation Facility. The algorithm paves the way for local reconstruction of large-size samples by the use of DEI-CT with small field of view based on synchrotron radiation source.

  10. SUNY beamline facilities at the National Synchrotron Light Source (Final Report)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Coppens, Philip

    2003-06-22

    The DOE sponsored SUNY synchrotron project has involved close cooperation among faculty at several SUNY campuses. A large number of students and postdoctoral associates have participated in its operation which was centered at the X3 beamline of the National Synchrotron Light Source at Brookhaven National Laboratory. Four stations with capabilities for Small Angle Scattering, Single Crystal and Powder and Surface diffraction and EXAFS were designed and operated with capability to perform experiments at very low as well as elevated temperatures and under high vacuum. A large amount of cutting-edge science was performed at the facility, which in addition provided excellentmore » training for students and postdoctoral scientists in the field.« less

  11. Experimental and Observational Studies of Molecular Hydrogen in Interstellar and Circumstellar Environments

    NASA Astrophysics Data System (ADS)

    Hoadley, Keri

    2017-08-01

    Understanding the evolution of gas over the lifetime of protoplanetary disks provides us with important clues about how planet formation mechanisms drive the diversity of exoplanetary systems observed to date. In the first part of my thesis, I discuss how I use fluorescent emission observations of molecular hydrogen (H2) in the far-ultraviolet (far-UV) with the Hubble Space Telescope to study the warm molecular regions (a < 10 AU) of planet-forming disks. I have created analytic disk models that produce synthetic H2 line profiles and statistically compare each disk realization with the data. I how the modeled radial distributions of H 2 help provide important constraints on the radiation properties of gas left in the inner disk of protoplanetary disks as they evolve. Additionally, I analyzed the absorption component of these fluorescence features, embedded within the hydrogen Lyman-alpha emission line produced by the accretion of material onto the host protostar. I present column density and temperature estimates for the H2 populations in each disk sightline, and discuss the behavior and possible spatial origins of these hot molecules. As part of my thesis, I address some observational requirements needed to gain further insights into the behavior of the warm, gaseous protoplanetary disk, focusing specifically on a spectrograph concept for the next-generation LUVOIR Surveyor. I discuss a testbed instrument, the Colorado High-resolution Echelle Stellar Spectrograph (CHESS), built as a demonstration of one component of the LUVOIR spectrograph and new technological improvements to UV optical components for the next generation of near- to far-UV astrophysical observatories. CHESS is a far-UV sounding rocket experiment designed to probe the warm and cool atoms and molecules near sites of recent star formation in the local interstellar medium. I present the science goals, design, research and development components, and calibration of the CHESS instrument. I provide results on observations taken during both launches of CHESS, with detailed analysis of the epsilon Per sightline, as inferred from the flight data. I conclude by providing future works and simple estimates of the performance of an instrument like CHESS on LUVOIR to study planet-forming environments.

  12. The Behavior of Warm Molecules in Planet-forming Disks and CHESS: a Pathfinder UV Spectrograph for the LUVOIR Surveyor

    NASA Astrophysics Data System (ADS)

    Hoadley, Keri; France, Kevin

    2017-01-01

    Understanding the evolution of gas over the lifetime of protoplanetary disks provides us with important clues about how planet formation mechanisms drive the diversity of exoplanetary systems observed to date. In the first part of my talk, I will discuss how we use emission line observations of molecular hydrogen (H2) in the far-ultraviolet (far-UV) with the Cosmic Origins Spectrograph (COS) on the Hubble Space Telescope to study the warm molecular regions (a < 10 AU) of planet-forming disks. We compare the observations with analytic disk models that produce synthetic H2 profiles, and we statistically determine the disk representations that best replicate the data. I will discuss the results of our comparisons and how the modeled radial distributions of H2 in the disk help provide important constraints on the effective density of gas left in the inner disk of protoplanetary disks at various disk evolutionary stages. Finally, I will talk about follow-up studies that look to connect the warm, UV-pumped molecular populations of the inner disk to thermally-excited molecules observed in similar regions of the disk in the near- to mid-IR.In the second part of my talk, I will discuss the observational requirements in the UV and IR band passes to gain further insights into the behavior of the warm, gaseous protoplanetary disk, focusing specifically on a spectrograph concept for the next-generation LUVOIR Surveyor. I will discuss a testbed instrument, the Colorado High-resolution Echelle Stellar Spectrograph (CHESS), built as a demonstration of one component of the LUVOIR spectrograph and new technological improvements to UV optical components for the next generation of near- to far-UV astrophysical observatories. CHESS is a far-UV sounding rocket experiment designed to probe the warm and cool atoms and molecules near sites of recent star formation in the local interstellar medium. I will talk about the science goals, design, research and development (R&D) components, and calibration of the CHESS instrument. I will end by presenting the initial data reduction and results of the flight observations taken during the second launch of CHESS.

  13. A Chess-Like Game for Teaching Engineering Students to Solve Large System of Simultaneous Linear Equations

    NASA Technical Reports Server (NTRS)

    Nguyen, Duc T.; Mohammed, Ahmed Ali; Kadiam, Subhash

    2010-01-01

    Solving large (and sparse) system of simultaneous linear equations has been (and continues to be) a major challenging problem for many real-world engineering/science applications [1-2]. For many practical/large-scale problems, the sparse, Symmetrical and Positive Definite (SPD) system of linear equations can be conveniently represented in matrix notation as [A] {x} = {b} , where the square coefficient matrix [A] and the Right-Hand-Side (RHS) vector {b} are known. The unknown solution vector {x} can be efficiently solved by the following step-by-step procedures [1-2]: Reordering phase, Matrix Factorization phase, Forward solution phase, and Backward solution phase. In this research work, a Game-Based Learning (GBL) approach has been developed to help engineering students to understand crucial details about matrix reordering and factorization phases. A "chess-like" game has been developed and can be played by either a single player, or two players. Through this "chess-like" open-ended game, the players/learners will not only understand the key concepts involved in reordering algorithms (based on existing algorithms), but also have the opportunities to "discover new algorithms" which are better than existing algorithms. Implementing the proposed "chess-like" game for matrix reordering and factorization phases can be enhanced by FLASH [3] computer environments, where computer simulation with animated human voice, sound effects, visual/graphical/colorful displays of matrix tables, score (or monetary) awards for the best game players, etc. can all be exploited. Preliminary demonstrations of the developed GBL approach can be viewed by anyone who has access to the internet web-site [4]!

  14. Kiloparsec Jet Properties of Hybrid, Low-, and High-Synchrotron-Peaked Blazars

    NASA Astrophysics Data System (ADS)

    Stanley, Ethan C.

    Blazars are a rare class of active galactic nucleus (AGN) with relativistic jets closely aligned with the line of sight. Many aspects of the environments and kiloparsec-scale jet structure are not fully understood. Hybrid and high synchrotron peaked (HSP) blazars are two types of blazar that provide unique opportunities to study these jets. Hybrid blazars appear to have jets of differing morphology on each side of their core, suggesting that external factors shape their jet morphology. Three hybrid sources were investigated in radio, optical, and X-ray wavelengths: 8C 1849+670, PKS 2216-038, and PKS 1045-188. For all three, X-ray emission was detected only from the approaching jet. All three had jet radio flux densities and emission mechanisms similar to higher-power FR II sources, but two had approaching jets similar to lower-power FR I sources. None of the three showed definitive signs of asymmetry in their external environments. These results agree with previous multiwavelength studies of hybrid sources that show a dominance of FR I approaching jets and FR II emission mechanisms. With the addition of these three hybrid sources, 13 have been studied in total. Eleven have FR I approaching jets, and eight of those have FR II emission mechanisms. These trends may be due to small number statistics, or they may indicate other factors are creating hybrid-like appearances. High synchrotron peaked blazars are defined by the frequency of the peak of their jet synchrotron emission. Some have shown extreme variability which would imply incredibly-powerful and well-aligned jets, but VLBA observations have measured only modest jet speeds. A radio survey was performed to measure the extended radio luminosity of a large sample of HSP sources. These sources were compared to the complete radio flux density limited MOJAVE 1.5 Jy sample. Flat spectrum radio quasars (FSRQs) showed significant overlap with low synchrotron peaked (LSP) BL Lacs in multiple parameters, which may suggest that many FSRQs are "masquerading'' as LSP BL Lacs. HSP BL Lacs showed slightly lower extended radio luminosities and significantly lower maximum apparent jet speeds, suggesting that they are intrinsically weaker sources. There was a good correlation between maximum apparent jet speed and extended radio luminosity, which supports using the extended radio luminosity as a measure of intrinsic jet power. There was a lack of TeV-detected sources with higher extended radio luminosities, which suggests TeV emission may favor low power jets or high synchrotron peak frequencies. The apparent low power of HSP sources and TeV-detected sources questions any model of TeV emission and variability that depends on the jet (or a part of it) being intrinsically powerful.

  15. ERP to chess stimuli reveal expert-novice differences in the amplitudes of N2 and P3 components.

    PubMed

    Wright, Michael J; Gobet, Fernand; Chassy, Philippe; Ramchandani, Payal Nanik

    2013-10-01

    ERP experiments were conducted to analyze the underlying neural events when chess players make simple judgments of a board position. Fourteen expert players and 14 age-matched novices viewed, for each of four tasks, 128 unique positions on a mini (4 × 4) chess board each presented for 0.5 s. The tasks were to respond: (a) if white king was in check, (b) if black knight was present, (c) if white king was not in check, and (d) if no black knight was present. Experts showed an enhanced N2 with check targets and a larger P3 with knight targets, relative to novices. Expert-novice differences in posterior N2 began as early as 240 ms on check-related searches. Results were consistent with the view that prolonged N2 components reflect matching of current perceptual input to memory, and thus are sensitive to experts' superior pattern recognition and memory retrieval of chunks. Copyright © 2013 Society for Psychophysiological Research.

  16. Quantum Chess: Making Quantum Phenomena Accessible

    NASA Astrophysics Data System (ADS)

    Cantwell, Christopher

    Quantum phenomena have remained largely inaccessible to the general public. There tends to be a scare factor associated with the word ``Quantum''. This is in large part due to the alien nature of phenomena such as superposition and entanglement. However, Quantum Computing is a very active area of research and one day we will have games that run on those quantum computers. Quantum phenomena such as superposition and entanglement will seem as normal as gravity. Is it possible to create such games today? Can we make games that are built on top of a realistic quantum simulation and introduce players of any background to quantum concepts in a fun and mentally stimulating way? One of the difficulties with any quantum simulation run on a classical computer is that the Hilbert space grows exponentially, making simulations of an appreciable size physically impossible due largely to memory restrictions. Here we will discuss the conception and development of Quantum Chess, and how to overcome some of the difficulties faced. We can then ask the question, ``What's next?'' What are some of the difficulties Quantum Chess still faces, and what is the future of quantum games?

  17. Deuterated water in low-mass protostars

    NASA Astrophysics Data System (ADS)

    Coutens, Audrey; Vastel, Charlotte; Chess Collaboration; Wish Collaboration; Hexos Collaboration

    2013-07-01

    In addition to its dominant role in the cooling of warm gas and in the oxygen chemistry, water is a primordial species in the emergence of life, and comets may have brought a large fraction to Earth to form the oceans. Observations of deuterated water are an important complement for studies of H2O to understand how water forms and how it has evolved from cold prestellar cores to protoplanetary disks and consequently oceans for the Earth's specific, but probably not isolated, case. Several deuterated water transitions were observed with the Herschel/HIFI (Heterodyne Instrument for Far Infrared) instrument towards three low-mass protostars: IRAS 16293-2422, NGC1333 IRAS4A and NGC1333 IRAS4B. In the first source, both HDO and D2O lines are detected, thanks to the unbiased spectral survey carried out by the CHESS key program (Vastel et al. 2010, Coutens et al. 2013a). In the framework of a collaboration between the CHESS, WISH and HEXOS programs, two HDO key lines were observed towards the two other protostars. In addition, complementary observations were carried out with several ground-based single-dish telescopes (IRAM-30m, JCMT, APEX). We used the non-LTE RATRAN spherical model (Hogerheijde & van der Tak 2000) to determine the HDO abundance distribution throughout the protostellar envelope. An abundance jump at 100 K is required to reproduce the line profiles. Indeed, water molecules trapped in the icy grain mantles thermally desorb in the hot corinos, the inner warm regions of the protostellar envelopes. We also obtain that it is necessary to add a water-rich external absorbing layer to reproduce the absorbing components of the HDO and D2O fundamental transitions in all sources (Coutens et al. 2012, 2013a,b). The results derived for the different sources will be then presented and discussed.

  18. Characterization of semiconductor materials using synchrotron radiation-based near-field infrared microscopy and nano-FTIR spectroscopy.

    PubMed

    Hermann, Peter; Hoehl, Arne; Ulrich, Georg; Fleischmann, Claudia; Hermelink, Antje; Kästner, Bernd; Patoka, Piotr; Hornemann, Andrea; Beckhoff, Burkhard; Rühl, Eckart; Ulm, Gerhard

    2014-07-28

    We describe the application of scattering-type near-field optical microscopy to characterize various semiconducting materials using the electron storage ring Metrology Light Source (MLS) as a broadband synchrotron radiation source. For verifying high-resolution imaging and nano-FTIR spectroscopy we performed scans across nanoscale Si-based surface structures. The obtained results demonstrate that a spatial resolution below 40 nm can be achieved, despite the use of a radiation source with an extremely broad emission spectrum. This approach allows not only for the collection of optical information but also enables the acquisition of near-field spectral data in the mid-infrared range. The high sensitivity for spectroscopic material discrimination using synchrotron radiation is presented by recording near-field spectra from thin films composed of different materials used in semiconductor technology, such as SiO2, SiC, SixNy, and TiO2.

  19. Diffraction-Enhanced Computed Tomographic Imaging of Growing Piglet Joints by Using a Synchrotron Light Source

    PubMed Central

    Rhoades, Glendon W; Belev, George S; Chapman, L Dean; Wiebe, Sheldon P; Cooper, David M; Wong, Adelaine TF; Rosenberg, Alan M

    2015-01-01

    The objective of this project was to develop and test a new technology for imaging growing joints by means of diffraction-enhanced imaging (DEI) combined with CT and using a synchrotron radiation source. DEI–CT images of an explanted 4-wk-old piglet stifle joint were acquired by using a 40-keV beam. The series of scanned slices was later ‘stitched’ together, forming a 3D dataset. High-resolution DEI-CT images demonstrated fine detail within all joint structures and tissues. Striking detail of vasculature traversing between bone and cartilage, a characteristic of growing but not mature joints, was demonstrated. This report documents for the first time that DEI combined with CT and a synchrotron radiation source can generate more detailed images of intact, growing joints than can currently available conventional imaging modalities. PMID:26310464

  20. 1993 CAT workshop on beamline optical designs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1993-11-01

    An Advanced Photon Source (APS) Collaborative Access Team (CAT) Workshop on Beamline Optical Designs was held at Argonne National Laboratory on July 26--27, 1993. The goal of this workshop was to bring together experts from various synchrotron sources to provide status reports on crystal, reflecting, and polarizing optics as a baseline for discussions of issues facing optical designers for CAT beamlines at the APS. Speakers from the European Synchrotron Radiation Facility (ESRF), the University of Chicago, the National Synchrotron Light Source, and the University of Manchester (England) described single- and double-crystal monochromators, mirrors, glass capillaries, and polarizing optics. Following thesemore » presentations, the 90 participants divided into three working groups: Crystal Optics Design, Reflecting Optics, and Optics for Polarization Studies. This volume contains copies of the presentation materials from all speakers, summaries of the three working groups, and a ``catalog`` of various monochromator designs.« less

  1. Medical Applications of Synchrotron Radiation

    DOE R&D Accomplishments Database

    Thomlinson, W.

    1991-10-01

    Ever since the first diagnostic x-ray was done in the United States on February 3, 1896, the application of ionizing radiation to the field of medicine has become increasingly important. Both in clinical medicine and basic research the use of x-rays for diagnostic imaging and radiotherapy is now widespread. Radiography, angiography, CAT and PETT scanning, mammography, and nuclear medicine are all examples of technologies developed to image the human anatomy. In therapeutic applications, both external and internal sources of radiation are applied to the battle against cancer. The development of dedicated synchrotron radiation sources has allowed exciting advances to take place in many of these applications. The new sources provide tunable, high-intensity monochromatic beams over a wide range of energies which can be tailored to specific programmatic needs. This paper surveys those areas of medical research in which synchrotron radiation facilities are actively involved.

  2. Observation of divergent-beam X-ray diffraction from a crystal of diamond using synchrotron radiation.

    PubMed

    Glazer, A M; Collins, S P; Zekria, D; Liu, J; Golshan, M

    2004-03-01

    In 1947 Kathleen Lonsdale conducted a series of experiments on X-ray diffraction using a divergent beam external to a crystal sample. Unlike the Kossel technique, where divergent X-rays are excited by the presence of fluorescing atoms within the crystal, the use of an external divergent source made it possible to study non-fluorescing crystals. The resulting photographs not only illustrated the complexity of X-ray diffraction from crystals in a truly beautiful way, but also demonstrated unprecedented experimental precision. This long-forgotten work is repeated here using a synchrotron radiation source and, once again, considerable merit is found in Lonsdale's technique. The results of this experiment suggest that, through the use of modern 'third-generation' synchrotron sources, divergent-beam diffraction could soon enjoy a renaissance for high-precision lattice-parameter determination and the study of crystal perfection.

  3. Radiological implications of top-off operation at national synchrotron light source-II

    NASA Astrophysics Data System (ADS)

    Job, P. K.; Casey, W. R.

    2011-08-01

    High current and low emittance have been specified to achieve ultra high brightness in the third generation medium energy Synchrotron Radiation Sources. This leads to the electron beam lifetime limited by Touschek scattering, and after commissioning may settle in at as low as ∼3 h. It may well be less in the early days of operation. At the same time, the intensity stability specified by the user community for the synchrotron beam is 1% or better. Given the anticipated lifetime of the beam, incremental filling called top-off injection at intervals on the order of ∼1 min will be required to maintain this beam stability. It is judged to be impractical to make these incremental fills by closing the beam shutters at each injection. In addition, closing the front end beam shutters during each injection will adversely affect the stability of beamline optics due to thermal cycling. Hence the radiological consequences of injection with front end beam shutters open must be evaluated. This paper summarizes results of radiological analysis carried out for the proposed top-off injection at National Synchrotron Light Source-II (NSLS-II) with beam shutters open.

  4. The synchrotron-self-Compton process in spherical geometries. I - Theoretical framework

    NASA Technical Reports Server (NTRS)

    Band, D. L.; Grindlay, J. E.

    1985-01-01

    Both spatial and spectral accuracies are stressed in the present method for the calculation of the synchrotron-self-Compton model in spherical geometries, especially in the partially opaque regime of the synchrotron spectrum of inhomogeneous sources that can span a few frequency decades and contribute a significant portion of the scattered flux. A formalism is developed that permits accurate calculation of incident photon density throughout an optically thin sphere. An approximation to the Klein-Nishina cross section is used to model the effects of variable electron and incident photon cutoffs, as well as the decrease in the cross section at high energies. General results are derived for the case of inhomogeneous sources with power law profiles in both electron density and magnetic field.

  5. Music and Mind: In Memoriam Professor Carlo Alberto Pagni, MD, PhD: February 13, 1931 -March 1, 2009.

    PubMed

    von Wild, Klaus R H

    2017-01-01

    Carlo Alberto Pagni, born in La Spezia, Italy, on February 13, 1931, was an eminent and respected professor of neurosurgery and chairman of the neurosurgical clinic of the University of Turin from 1980 to 2003. He died on March 1, 2009. As a professor of neurology and neurological surgery he was renowned as an expert on vascular, tumor, and functional neurosurgery. Beyond the Italian Neurosurgical Society, he was the doyen of functional neurosurgery, specializing in motor cortex stimulation for the treatment of focal dystonia, Parkinson's disease, and postictal spasticity and pain. His home was his castle, and his family was fundamental to his life. He shared with his wife, Sandra, his passion for piano playing and for their remarkable library, and together with friends, he and his wife enjoyed dinners with fine food and Barolo wines. Listening to this Grand Seigneur talking about and explaining the music of, above all, Ludwig van Beethoven, and Richard Wagner, one felt he was emotionally just "music and mind". You can imagine this from his books on music, chess, and neuroscience. Indeed, he adored playing correspondence chess worldwide. A sportsman too, he loved hiking, mountaineering, skiing, swimming, and fishing. Nature was his source for slowing down, for regenerating, and for collecting his strength for new projects and new challenges. Friends will remember Dr. Pagni as a Grand Seigneur.

  6. Radiological considerations for bulk shielding calculations of national synchrotron light source-II

    NASA Astrophysics Data System (ADS)

    Job, Panakkal K.; Casey, William R.

    2011-12-01

    Brookhaven National Laboratory is designing a new electron synchrotron for scientific research using synchrotron radiation. This facility, called the “National Synchrotron Light Source II” (NSLS-II), will provide x-ray radiation of ultra-high brightness and exceptional spatial and energy resolution. It will also provide advanced insertion devices, optics, detectors and robotics, and a suite of scientific instruments designed to maximize the scientific output of the facility. The project scope includes the design, construction, installation, and commissioning of the following accelerators: a 200 MeV linac, a booster synchrotron operating from 200 MeV to 3.0 GeV, and the storage ring which stores a maximum of 500 mA current of electrons at an energy of 3.0 GeV. It is planned to operate the facility primarily in a top-off mode, thereby maintaining the maximum variation in stored beam current to <1%. Because of the very demanding requirements for beam emittance and synchrotron radiation brilliance, the beam life-time is expected to be quite low, on the order of 2 h. Analysis of the bulk shielding for operating this facility and the input parameters used for this analysis have been discussed in this paper. The characteristics of each of the accelerators and their operating modes have been summarized with the input assumptions for the bulk shielding analysis.

  7. Herschel CHESS discovery of the fossil cloud that gave birth to the Trapezium and Orion KL

    NASA Astrophysics Data System (ADS)

    López-Sepulcre, A.; Kama, M.; Ceccarelli, C.; Dominik, C.; Caux, E.; Fuente, A.; Alonso-Albi, T.

    2013-01-01

    Context. The Orion A molecular complex is a nearby (420 pc), very well studied stellar nursery that is believed to contain examples of triggered star formation. Aims: As part of the Herschel guaranteed time key programme CHESS, we present the discovery of a diffuse gas component in the foreground of the intermediate-mass protostar OMC-2 FIR 4, located in the Orion A region. Methods: Making use of the full HIFI spectrum of OMC-2 FIR 4 obtained in CHESS, we detected several ground-state lines from OH+, H2O+, HF, and CH+, all of them seen in absorption against the dust continuum emission of the protostar's envelope. We derived column densities for each species, as well as an upper limit to the column density of the undetected H3O+. In order to model and characterise the foreground cloud, we used the Meudon PDR code to run a homogeneous grid of models that spans a reasonable range of densities, visual extinctions, cosmic ray ionisation rates and far-ultraviolet (FUV) radiation fields, and studied the implications of adopting the Orion Nebula extinction properties instead of the standard interstellar medium ones. Results: The detected absorption lines peak at a velocity of 9 km s-1, which is blue-shifted by 2 km s-1 with respect to the systemic velocity of OMC-2 FIR 4 (VLSR = 11.4 km s-1). The results of our modelling indicate that the foreground cloud is composed of predominantly neutral diffuse gas (nH = 100 cm-3) and is heavily irradiated by an external source of FUV that most likely arises from the nearby Trapezium OB association. The cloud is 6 pc thick and bears many similarities with the so-called C+ interface between Orion-KL and the Trapezium cluster, 2 pc south of OMC-2 FIR 4. Conclusions: We conclude that the foreground cloud we detected is an extension of the C+ interface seen in the direction of Orion KL, and interpret it to be the remains of the parental cloud of OMC-1, which extends from OMC-1 up to OMC-2.

  8. Longevity of outstanding sporting achievers: Mind versus muscle

    PubMed Central

    Smerdon, David C.; Clarke, Philip M.

    2018-01-01

    Background While there is strong evidence showing the survival advantage of elite athletes, much less is known about those engaged in mind sports such as chess. This study aimed to examine the overall as well as regional survival of International Chess Grandmasters (GMs) with a reference to the general population, and compare relative survival (RS) of GMs with that of Olympic medallists (OMs). Methods Information on 1,208 GMs and 15,157 OMs, respectively, from 28 countries were extracted from the publicly available data sources. The Kaplan-Meier method was used to estimate the survival rates of the GMs. A Cox proportional hazards model was used to adjust the survival for region, year at risk, age at risk and sex, and to estimate the life expectancy of the GMs. The RS rate was computed by matching each GM or OM by year at risk, age at risk and sex to the life table of the country the individual represented. Results The survival rates of GMs at 30 and 60 years since GM title achievement were 87% and 15%, respectively. The life expectancy of GMs at the age of 30 years (which is near the average age when they attained a GM title) was 53.6 ([95% CI]: 47.7–58.5) years, which is significantly greater than the overall weighted mean life expectancy of 45.9 years for the general population. Compared to Eastern Europe, GMs in North America (HR [95% CI]: 0.51 [0.29–0.88]) and Western Europe (HR [95% CI]: 0.53 [0.34–0.83]) had a longer lifespan. The RS analysis showed that both GMs and OMs had a significant survival advantage over the general population, and there was no statistically significant difference in the RS of GMs (RS [95% CI]: 1.14 [1.08–1.20]) compared to OMs: (RS [95% CI]: 1.09 [1.07–1.11]) at 30 years. Conclusion Elite chess players live longer than the general population and have a similar survival advantage to elite competitors in physical sports. PMID:29723296

  9. Elemental Composition of Mars Return Samples Using X-Ray Fluorescence Imaging at the National Synchrotron Light Source II

    NASA Astrophysics Data System (ADS)

    Thieme, J.; Hurowitz, J. A.; Schoonen, M. A.; Fogelqvist, E.; Gregerson, J.; Farley, K. A.; Sherman, S.; Hill, J.

    2018-04-01

    NSLS-II at BNL provides a unique and critical capability to perform assessments of the elemental composition and the chemical state of Mars returned samples using synchrotron radiation X-ray fluorescence imaging and X-ray absorption spectroscopy.

  10. Plastique: A synchrotron radiation beamline for time resolved fluorescence in the frequency domain

    NASA Astrophysics Data System (ADS)

    De Stasio, Gelsomina; Zema, N.; Antonangeli, F.; Savoia, A.; Parasassi, T.; Rosato, N.

    1991-06-01

    PLASTIQUE is the only synchrotron radiation beamline in the world that performs time resolved fluorescence experiments in frequency domain. These experiments are extremely valuable sources of information on the structure and dynamics of molecules. We describe the beamline and some initial data.

  11. Planck intermediate results. VII. Statistical properties of infrared and radio extragalactic sources from the Planck Early Release Compact Source Catalogue at frequencies between 100 and 857 GHz

    NASA Astrophysics Data System (ADS)

    Planck Collaboration; Ade, P. A. R.; Aghanim, N.; Argüeso, F.; Arnaud, M.; Ashdown, M.; Atrio-Barandela, F.; Aumont, J.; Baccigalupi, C.; Balbi, A.; Banday, A. J.; Barreiro, R. B.; Battaner, E.; Benabed, K.; Benoît, A.; Bernard, J.-P.; Bersanelli, M.; Bethermin, M.; Bhatia, R.; Bonaldi, A.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Burigana, C.; Cabella, P.; Cardoso, J.-F.; Catalano, A.; Cayón, L.; Chamballu, A.; Chary, R.-R.; Chen, X.; Chiang, L.-Y.; Christensen, P. R.; Clements, D. L.; Colafrancesco, S.; Colombi, S.; Colombo, L. P. L.; Coulais, A.; Crill, B. P.; Cuttaia, F.; Danese, L.; Davis, R. J.; de Bernardis, P.; de Gasperis, G.; de Zotti, G.; Delabrouille, J.; Dickinson, C.; Diego, J. M.; Dole, H.; Donzelli, S.; Doré, O.; Dörl, U.; Douspis, M.; Dupac, X.; Efstathiou, G.; Enßlin, T. A.; Eriksen, H. K.; Finelli, F.; Forni, O.; Fosalba, P.; Frailis, M.; Franceschi, E.; Galeotta, S.; Ganga, K.; Giard, M.; Giardino, G.; Giraud-Héraud, Y.; González-Nuevo, J.; Górski, K. M.; Gregorio, A.; Gruppuso, A.; Hansen, F. K.; Harrison, D.; Henrot-Versillé, S.; Hernández-Monteagudo, C.; Herranz, D.; Hildebrandt, S. R.; Hivon, E.; Hobson, M.; Holmes, W. A.; Jaffe, T. R.; Jaffe, A. H.; Jagemann, T.; Jones, W. C.; Juvela, M.; Keihänen, E.; Kisner, T. S.; Kneissl, R.; Knoche, J.; Knox, L.; Kunz, M.; Kurinsky, N.; Kurki-Suonio, H.; Lagache, G.; Lähteenmäki, A.; Lamarre, J.-M.; Lasenby, A.; Lawrence, C. R.; Leonardi, R.; Lilje, P. B.; López-Caniego, M.; Macías-Pérez, J. F.; Maino, D.; Mandolesi, N.; Maris, M.; Marshall, D. J.; Martínez-González, E.; Masi, S.; Massardi, M.; Matarrese, S.; Mazzotta, P.; Melchiorri, A.; Mendes, L.; Mennella, A.; Mitra, S.; Miville-Deschènes, M.-A.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Munshi, D.; Murphy, J. A.; Naselsky, P.; Nati, F.; Natoli, P.; Nørgaard-Nielsen, H. U.; Noviello, F.; Novikov, D.; Novikov, I.; Osborne, S.; Pajot, F.; Paladini, R.; Paoletti, D.; Partridge, B.; Pasian, F.; Patanchon, G.; Perdereau, O.; Perotto, L.; Perrotta, F.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Ponthieu, N.; Popa, L.; Poutanen, T.; Pratt, G. W.; Prunet, S.; Puget, J.-L.; Rachen, J. P.; Reach, W. T.; Rebolo, R.; Reinecke, M.; Renault, C.; Ricciardi, S.; Riller, T.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Rowan-Robinson, M.; Rubiño-Martín, J. A.; Rusholme, B.; Sajina, A.; Sandri, M.; Savini, G.; Scott, D.; Smoot, G. F.; Starck, J.-L.; Sudiwala, R.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tauber, J. A.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Tucci, M.; Türler, M.; Valenziano, L.; Van Tent, B.; Vielva, P.; Villa, F.; Vittorio, N.; Wade, L. A.; Wandelt, B. D.; White, M.; Yvon, D.; Zacchei, A.; Zonca, A.

    2013-02-01

    We make use of the Planck all-sky survey to derive number counts and spectral indices of extragalactic sources - infrared and radio sources - from the Planck Early Release Compact Source Catalogue (ERCSC) at 100 to 857 GHz (3 mm to 350 μm). Three zones (deep, medium and shallow) of approximately homogeneous coverage are used to permit a clean and controlled correction for incompleteness, which was explicitly not done for the ERCSC, as it was aimed at providing lists of sources to be followed up. Our sample, prior to the 80% completeness cut, contains between 217 sources at 100 GHz and 1058 sources at 857 GHz over about 12 800 to 16 550 deg2 (31 to 40% of the sky). After the 80% completeness cut, between 122 and 452 and sources remain, with flux densities above 0.3 and 1.9 Jy at 100 and 857 GHz. The sample so defined can be used for statistical analysis. Using the multi-frequency coverage of the Planck High Frequency Instrument, all the sources have been classified as either dust-dominated (infrared galaxies) or synchrotron-dominated (radio galaxies) on the basis of their spectral energy distributions (SED). Our sample is thus complete, flux-limited and color-selected to differentiate between the two populations. We find an approximately equal number of synchrotron and dusty sources between 217 and 353 GHz; at 353 GHz or higher (or 217 GHz and lower) frequencies, the number is dominated by dusty (synchrotron) sources, as expected. For most of the sources, the spectral indices are also derived. We provide for the first time counts of bright sources from 353 to 857 GHz and the contributions from dusty and synchrotron sources at all HFI frequencies in the key spectral range where these spectra are crossing. The observed counts are in the Euclidean regime. The number counts are compared to previously published data (from earlier Planck results, Herschel, BLAST, SCUBA, LABOCA, SPT, and ACT) and models taking into account both radio or infrared galaxies, and covering a large range of flux densities. We derive the multi-frequency Euclidean level - the plateau in the normalised differential counts at high flux-density - and compare it to WMAP, Spitzer and IRAS results. The submillimetre number counts are not well reproduced by current evolution models of dusty galaxies, whereas the millimetre part appears reasonably well fitted by the most recent model for synchrotron-dominated sources. Finally we provide estimates of the local luminosity density of dusty galaxies, providing the first such measurements at 545 and 857 GHz. Appendices are available in electronic form at http://www.aanda.orgCorresponding author: herve.dole@ias.u-psud.fr

  12. AI-BL1.0: a program for automatic on-line beamline optimization using the evolutionary algorithm.

    PubMed

    Xi, Shibo; Borgna, Lucas Santiago; Zheng, Lirong; Du, Yonghua; Hu, Tiandou

    2017-01-01

    In this report, AI-BL1.0, an open-source Labview-based program for automatic on-line beamline optimization, is presented. The optimization algorithms used in the program are Genetic Algorithm and Differential Evolution. Efficiency was improved by use of a strategy known as Observer Mode for Evolutionary Algorithm. The program was constructed and validated at the XAFCA beamline of the Singapore Synchrotron Light Source and 1W1B beamline of the Beijing Synchrotron Radiation Facility.

  13. A NEW THERMIONIC RF ELECTRON GUN FOR SYNCHROTRON LIGHT SOURCES

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kutsaev, Sergey; Agustsson, R.; Hartzell, J

    A thermionic RF gun is a compact and efficient source of electrons used in many practical applications. RadiaBeam Systems and the Advanced Photon Source at Argonne National Laboratory collaborate in developing of a reliable and robust thermionic RF gun for synchrotron light sources which would offer substantial improvements over existing thermionic RF guns and allow stable operation with up to 1A of beam peak current at a 100 Hz pulse repetition rate and a 1.5 μs RF pulse length. In this paper, we discuss the electromagnetic and engineering design of the cavity and report the progress towards high power testsmore » of the cathode assembly of the new gun.« less

  14. Six Suggestions for Research on Games in Cognitive Science.

    PubMed

    Chabris, Christopher F

    2017-04-01

    Games are more varied and occupy more of daily life than ever before. At the same time, the tools available to study game play and players are more powerful than ever, especially massive data sets from online platforms and computational engines that can accurately evaluate human decisions. This essay offers six suggestions for future cognitive science research on games: (1) Don't forget about chess, (2) Look beyond action games and chess, (3) Use (near)-optimal play to understand human play and players, (4) Investigate social phenomena, (5) Raise the standards for studies of games as treatments, (6) Talk to real experts. Copyright © 2017 Cognitive Science Society, Inc.

  15. THE ENVIRONMENT AND DISTRIBUTION OF EMITTING ELECTRONS AS A FUNCTION OF SOURCE ACTIVITY IN MARKARIAN 421

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mankuzhiyil, Nijil; Ansoldi, Stefano; Persic, Massimo

    2011-05-20

    For the high-frequency-peaked BL Lac object Mrk 421, we study the variation of the spectral energy distribution (SED) as a function of source activity, from quiescent to active. We use a fully automatized {chi}{sup 2}-minimization procedure, instead of the 'eyeball' procedure more commonly used in the literature, to model nine SED data sets with a one-zone synchrotron self-Compton (SSC) model and examine how the model parameters vary with source activity. The latter issue can finally be addressed now, because simultaneous broadband SEDs (spanning from optical to very high energy photon) have finally become available. Our results suggest that in Mrkmore » 421 the magnetic field (B) decreases with source activity, whereas the electron spectrum's break energy ({gamma}{sub br}) and the Doppler factor ({delta}) increase-the other SSC parameters turn out to be uncorrelated with source activity. In the SSC framework, these results are interpreted in a picture where the synchrotron power and peak frequency remain constant with varying source activity, through a combination of decreasing magnetic field and increasing number density of {gamma} {<=} {gamma}{sub br} electrons: since this leads to an increased electron-photon scattering efficiency, the resulting Compton power increases, and so does the total (= synchrotron plus Compton) emission.« less

  16. Ultra-spatial synchrotron radiation for imaging molecular chemical structure: Applications in plant and animal studies

    DOE PAGES

    Yu, Peiqiang

    2007-01-01

    Synchrotron-based Fourier transform infrared microspectroscopy (S-FTIR) has been developed as a rapid, direct, non-destructive, bioanalytical technique. This technique takes advantage of synchrotron light brightness and small effective source size and is capable of exploring the molecular chemical features and make-up within microstructures of a biological tissue without destruction of inherent structures at ultra-spatial resolutions within cellular dimension. To date there has been very little application of this advanced synchrotron technique to the study of plant and animal tissues' inherent structure at a cellular or subcellular level. In this article, a novel approach was introduced to show the potential of themore » newly developed, advanced synchrotron-based analytical technology, which can be used to reveal molecular structural-chemical features of various plant and animal tissues.« less

  17. Applications of synchrotron-based spectroscopic techniques in studying nucleic acids and nucleic acid-functionalized nanomaterials

    PubMed Central

    Wu, Peiwen; Yu, Yang; McGhee, Claire E.; Tan, Li Huey

    2014-01-01

    In this review, we summarize recent progresses in the application of synchrotron-based spectroscopic techniques for nucleic acid research that takes advantage of high-flux and high-brilliance electromagnetic radiation from synchrotron sources. The first section of the review focuses on the characterization of the structure and folding processes of nucleic acids using different types of synchrotron-based spectroscopies, such as X-ray absorption spectroscopy, X-ray emission spectroscopy, X-ray photoelectron spectroscopy, synchrotron radiation circular dichroism, X-ray footprinting and small-angle X-ray scattering. In the second section, the characterization of nucleic acid-based nanostructures, nucleic acid-functionalized nanomaterials and nucleic acid-lipid interactions using these spectroscopic techniques is summarized. Insights gained from these studies are described and future directions of this field are also discussed. PMID:25205057

  18. Applications of synchrotron-based spectroscopic techniques in studying nucleic acids and nucleic acid-functionalized nanomaterials

    DOE PAGES

    Wu, Peiwen; Yu, Yang; McGhee, Claire E.; ...

    2014-09-10

    In this paper, we summarize recent progress in the application of synchrotron-based spectroscopic techniques for nucleic acid research that takes advantage of high-flux and high-brilliance electromagnetic radiation from synchrotron sources. The first section of the review focuses on the characterization of the structure and folding processes of nucleic acids using different types of synchrotron-based spectroscopies, such as X-ray absorption spectroscopy, X-ray emission spectroscopy, X-ray photoelectron spectroscopy, synchrotron radiation circular dichroism, X-ray footprinting and small-angle X-ray scattering. In the second section, the characterization of nucleic acid-based nanostructures, nucleic acid-functionalized nanomaterials and nucleic acid-lipid interactions using these spectroscopic techniques is summarized. Insightsmore » gained from these studies are described and future directions of this field are also discussed.« less

  19. Polarized Negative Light Ions at the Cooler Synchrotron COSY/Juelich

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gebel, R.; Felden, O.; Rossen, P. von

    2005-04-06

    The polarized ion source at the cooler synchrotron facility COSY of the research centre Juelich in Germany delivers negative polarized protons or deuterons for medium energy experiments. The polarized ion source, originally built by the universities of Bonn, Erlangen and Cologne, is based on the colliding beams principle, using after an upgrade procedure an intense pulsed neutralized caesium beam for charge exchange with a pulsed highly polarized hydrogen beam. The source is operated at 0.5 Hz repetition rate with 20 ms pulse length, which is the maximum useful length for the injection into the synchrotron. Routinely intensities of 20 {mu}Amore » are delivered for injection into the cyclotron of the COSY facility. For internal targets the intensity of 2 mA and a polarization up to 90% have been reached. Reliable long-term operation for experiments at COSY for up to 9 weeks has been achieved. Since 2003 polarized deuterons with different combinations of vector and tensor polarization were delivered to experiments.« less

  20. Refurbishment of a used in-vacuum undulator from the National Synchrotron Light Source for the National Synchrotron Light Source-II ring

    DOE PAGES

    Tanabe, Toshiya; Bassan, Harmanpreet; Broadbent, Andrew; ...

    2017-08-01

    The National Synchrotron Light Source (NSLS) ceased operation in September 2014 and was succeeded by NSLS-II. There were four in-vacuum undulators (IVUs) in operation at NSLS. The most recently constructed IVU for NSLS was the mini-gap undulator (MGU-X25, to be renamed IVU18 for NSLS-II), which was constructed in 2006. This device was selected to be reused for the New York Structural Biology Consortium Microdiffraction beamline at NSLS-II. At the time of construction, IVU18 was a state-of-the-art undulator designed to be operated as a cryogenic permanent-magnet undulator. Due to the more stringent field quality and impedance requirements of the NSLS-II ring,more » the transition region was redesigned. The control system was also updated to NSLS-II specifications. As a result, this paper reports the details of the IVU18 refurbishment activities including additional magnetic measurement and tuning.« less

  1. Trace element abundance determinations by Synchrotron X Ray Fluorescence (SXRF) on returned comet nucleus mineral grains

    NASA Technical Reports Server (NTRS)

    Flynn, G. J.; Sutton, S. R.

    1989-01-01

    Trace element analyses were performed on bulk cosmic dust particles by Proton Induced X Ray Emission (PIXE) and Synchrotron X Ray Fluorescence (SXRF). When present at or near chondritic abundances the trace elements K, Ti, Cr, Mn, Cu, Zn, Ga, Ge, Se, and Br are presently detectable by SXRF in particles of 20 micron diameter. Improvements to the SXRF analysis facility at the National Synchrotron Light Source presently underway should increase the range of detectable elements and permit the analysis of smaller samples. In addition the Advanced Photon Source will be commissioned at Argonne National Laboratory in 1995. This 7 to 8 GeV positron storage ring, specifically designed for high-energy undulator and wiggler insertion devices, will be an ideal source for an x ray microprobe with one micron spatial resolution and better than 100 ppb elemental sensitivity for most elements. Thus trace element analysis of individual micron-sized grains should be possible by the time of the comet nucleus sample return mission.

  2. Refurbishment of a used in-vacuum undulator from the National Synchrotron Light Source for the National Synchrotron Light Source-II ring

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tanabe, Toshiya; Bassan, Harmanpreet; Broadbent, Andrew

    The National Synchrotron Light Source (NSLS) ceased operation in September 2014 and was succeeded by NSLS-II. There were four in-vacuum undulators (IVUs) in operation at NSLS. The most recently constructed IVU for NSLS was the mini-gap undulator (MGU-X25, to be renamed IVU18 for NSLS-II), which was constructed in 2006. This device was selected to be reused for the New York Structural Biology Consortium Microdiffraction beamline at NSLS-II. At the time of construction, IVU18 was a state-of-the-art undulator designed to be operated as a cryogenic permanent-magnet undulator. Due to the more stringent field quality and impedance requirements of the NSLS-II ring,more » the transition region was redesigned. The control system was also updated to NSLS-II specifications. As a result, this paper reports the details of the IVU18 refurbishment activities including additional magnetic measurement and tuning.« less

  3. Glycoscience@Synchrotron: Synchrotron radiation applied to structural glycoscience

    PubMed Central

    de Sanctis, Daniele

    2017-01-01

    Synchrotron radiation is the most versatile way to explore biological materials in different states: monocrystalline, polycrystalline, solution, colloids and multiscale architectures. Steady improvements in instrumentation have made synchrotrons the most flexible intense X-ray source. The wide range of applications of synchrotron radiation is commensurate with the structural diversity and complexity of the molecules and macromolecules that form the collection of substrates investigated by glycoscience. The present review illustrates how synchrotron-based experiments have contributed to our understanding in the field of structural glycobiology. Structural characterization of protein–carbohydrate interactions of the families of most glycan-interacting proteins (including glycosyl transferases and hydrolases, lectins, antibodies and GAG-binding proteins) are presented. Examples concerned with glycolipids and colloids are also covered as well as some dealing with the structures and multiscale architectures of polysaccharides. Insights into the kinetics of catalytic events observed in the crystalline state are also presented as well as some aspects of structure determination of protein in solution. PMID:28684994

  4. Omega Dante Soft X-Ray Power Diagnostic Component Calibration at the National Synchrotron Light Source

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Campbell, K; Weber, F; Dewald, E

    2004-04-15

    The Dante soft x-ray spectrometer installed on the Omega laser facility at the Laboratory for Laser Energetics, University of Rochester is a twelve-channel filter-edge defined x-ray power diagnostic. It is used to measure the absolute flux from direct drive, indirect drive (hohlraums) and other plasma sources. Calibration efforts using two beam lines, U3C (50eV-1keV) and X8A (1keV-6keV) at the National Synchrotron Light Source (NSLS) have been implemented to insure the accuracy of these measurements. We have calibrated vacuum x-ray diodes, mirrors and filters.

  5. The stopped-drop method: a novel setup for containment-free and time-resolved measurements

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schiener, Andreas; Seifert, Soenke; Magerl, Andreas

    2016-03-01

    A novel setup for containment-free time-resolved experiments at a free-hanging drop is reported. Within a dead-time of 100 ms a drop of mixed reactant solutions is formed and the time evolution of a reaction can be followed from thereon by various techniques. As an example, a small-angle X-ray scattering study on the formation mechanism of EDTA-stabilized CdS both at a synchrotron and a laboratory X-ray source is presented here. While the evolution can be followed with one drop only at a synchrotron source, a stroboscopic mode with many drops is preferable for the laboratory source.

  6. Numerical calculations of spectral turnover and synchrotron self-absorption in CSS and GPS radio sources

    NASA Astrophysics Data System (ADS)

    Jeyakumar, S.

    2016-06-01

    The dependence of the turnover frequency on the linear size is presented for a sample of Giga-hertz Peaked Spectrum and Compact Steep Spectrum radio sources derived from complete samples. The dependence of the luminosity of the emission at the peak frequency with the linear size and the peak frequency is also presented for the galaxies in the sample. The luminosity of the smaller sources evolve strongly with the linear size. Optical depth effects have been included to the 3D model for the radio source of Kaiser to study the spectral turnover. Using this model, the observed trend can be explained by synchrotron self-absorption. The observed trend in the peak-frequency-linear-size plane is not affected by the luminosity evolution of the sources.

  7. On the Possibility of Acceleration of Polarized Protons in the Synchrotron Nuclotron

    NASA Astrophysics Data System (ADS)

    Shatunov, Yu. M.; Koop, I. A.; Otboev, A. V.; Mane, S. P.; Shatunov, P. Yu.

    2018-05-01

    One of the main tasks of the NICA project is to produce colliding beams of polarized protons. It is planned to accelerate polarized protons from the source to the maximum energy in the existing proton synchrotron. We consider all depolarizing spin resonances in the Nuclotron and propose methods to overcome them.

  8. Bioimaging of cells and tissues using accelerator-based sources.

    PubMed

    Petibois, Cyril; Cestelli Guidi, Mariangela

    2008-07-01

    A variety of techniques exist that provide chemical information in the form of a spatially resolved image: electron microprobe analysis, nuclear microprobe analysis, synchrotron radiation microprobe analysis, secondary ion mass spectrometry, and confocal fluorescence microscopy. Linear (LINAC) and circular (synchrotrons) particle accelerators have been constructed worldwide to provide to the scientific community unprecedented analytical performances. Now, these facilities match at least one of the three analytical features required for the biological field: (1) a sufficient spatial resolution for single cell (< 1 mum) or tissue (<1 mm) analyses, (2) a temporal resolution to follow molecular dynamics, and (3) a sensitivity in the micromolar to nanomolar range, thus allowing true investigations on biological dynamics. Third-generation synchrotrons now offer the opportunity of bioanalytical measurements at nanometer resolutions with incredible sensitivity. Linear accelerators are more specialized in their physical features but may exceed synchrotron performances. All these techniques have become irreplaceable tools for developing knowledge in biology. This review highlights the pros and cons of the most popular techniques that have been implemented on accelerator-based sources to address analytical issues on biological specimens.

  9. MICROSCANNING XRF, XANES, AND XRD STUDIES OF THEDECORATED SURFACE OF ROMAN TERRA SIGILLATA CERAMICS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mirguet, C.; Sciau, P.; Goudeau, P.

    Different microscanning synchrotron techniques were used to better understand the elaboration process and origins of Terra Sigillata potteries from the Roman period. A mixture Gallic slip sample cross-section showing red and yellow colors was studied. The small (micron) size of the X-ray beam available at Stanford Synchrotron Radiation Laboratory (SSRL) and Advanced Light Source (ALS) synchrotron sources, coupled with the use of a sample scanning stage allowed us to spatially resolve the distribution of the constitutive mineral phases related to the chemical composition. Results show that red color is a result of iron-rich hematite crystals and the yellow part ismore » a result of the presence of Ti-rich rutile-type phase (brookite). Volcanic-type clay is at the origin of these marble Terra Sigillata.« less

  10. Mix-and-diffuse serial synchrotron crystallography

    DOE PAGES

    Beyerlein, Kenneth R.; Dierksmeyer, Dennis; Mariani, Valerio; ...

    2017-10-09

    Unravelling the interaction of biological macromolecules with ligands and substrates at high spatial and temporal resolution remains a major challenge in structural biology. The development of serial crystallography methods at X-ray free-electron lasers and subsequently at synchrotron light sources allows new approaches to tackle this challenge. Here, a new polyimide tape drive designed for mix-and-diffuse serial crystallography experiments is reported. The structure of lysozyme bound by the competitive inhibitor chitotriose was determined using this device in combination with microfluidic mixers. The electron densities obtained from mixing times of 2 and 50 s show clear binding of chitotriose to the enzymemore » at a high level of detail. Here, the success of this approach shows the potential for high-throughput drug screening and even structural enzymology on short timescales at bright synchrotron light sources.« less

  11. Mix-and-diffuse serial synchrotron crystallography

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Beyerlein, Kenneth R.; Dierksmeyer, Dennis; Mariani, Valerio

    Unravelling the interaction of biological macromolecules with ligands and substrates at high spatial and temporal resolution remains a major challenge in structural biology. The development of serial crystallography methods at X-ray free-electron lasers and subsequently at synchrotron light sources allows new approaches to tackle this challenge. Here, a new polyimide tape drive designed for mix-and-diffuse serial crystallography experiments is reported. The structure of lysozyme bound by the competitive inhibitor chitotriose was determined using this device in combination with microfluidic mixers. The electron densities obtained from mixing times of 2 and 50 s show clear binding of chitotriose to the enzymemore » at a high level of detail. Here, the success of this approach shows the potential for high-throughput drug screening and even structural enzymology on short timescales at bright synchrotron light sources.« less

  12. National Synchrotron Light Source II storage ring vacuum systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hseuh, Hsiao-Chaun, E-mail: hseuh@bnl.gov; Hetzel, Charles; Leng, Shuwei

    2016-05-15

    The National Synchrotron Light Source II, completed in 2014, is a 3-GeV synchrotron radiation (SR) facility at Brookhaven National Laboratory and has been in steady operation since. With a design electron current of 500 mA and subnanometer radians horizontal emittance, this 792-m circumference storage ring is providing the highest flux and brightness x-ray beam for SR users. The majority of the storage ring vacuum chambers are made of extruded aluminium. Chamber sections are interconnected using low-impedance radiofrequency shielded bellows. SR from the bending magnets is intercepted by water-cooled compact photon absorbers resided in the storage ring chambers. This paper presents themore » design of the storage ring vacuum system, the fabrication of vacuum chambers and other hardware, the installation, the commissioning, and the continuing beam conditioning of the vacuum systems.« less

  13. A Model Describing Stable Coherent Synchrotron Radiation in Storage Rings

    NASA Astrophysics Data System (ADS)

    Sannibale, F.; Byrd, J. M.; Loftsdóttir, Á.; Venturini, M.; Abo-Bakr, M.; Feikes, J.; Holldack, K.; Kuske, P.; Wüstefeld, G.; Hübers, H.-W.; Warnock, R.

    2004-08-01

    We present a model describing high power stable broadband coherent synchrotron radiation (CSR) in the terahertz frequency region in an electron storage ring. The model includes distortion of bunch shape from the synchrotron radiation (SR), which enhances higher frequency coherent emission, and limits to stable emission due to an instability excited by the SR wakefield. It gives a quantitative explanation of several features of the recent observations of CSR at the BESSYII storage ring. We also use this model to optimize the performance of a source for stable CSR emission.

  14. Focusing of white synchrotron radiation using large-acceptance cylindrical refractive lenses made of single – crystal diamond

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Polikarpov, M., E-mail: polikarpov.maxim@mail.ru; Snigireva, I.; Snigirev, A.

    2016-07-27

    Large-aperture cylindrical refractive lenses were manufactured by laser cutting of single-crystal diamond. Five linear single lenses with apertures of 1 mm and the depth of the structure of 1.2 mm were fabricated and tested at the ESRF ID06 beamline performing the focusing of white-beam synchrotron radiation. Uniform linear focus was stable during hours of exposure, representing such lenses as pre-focusing and collimating devices suitable for the front-end sections of today synchrotron radiation sources.

  15. Updating the Synchrotron Radiation Monitor at TLS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kuo, C. H.; Hsu, S. Y.; Wang, C. J.

    2007-01-19

    The synchrotron radiation monitor provides useful information to support routine operation and physics experiments using the beam. Precisely knowing the profile of the beam helps to improve machine performance. The synchrotron radiation monitor at the Taiwan Light Source (TLS) was recently upgraded. The optics and modeling were improved to increase the accuracy of measurement in the small beam size. A high-performance IEEE-1394 digital CCD camera was used to improve the quality of images and extend the dynamic range of measurement. The image analysis is also improved. This report summarizes status and results.

  16. Propagation-based phase-contrast x-ray tomography of cochlea using a compact synchrotron source.

    PubMed

    Töpperwien, Mareike; Gradl, Regine; Keppeler, Daniel; Vassholz, Malte; Meyer, Alexander; Hessler, Roland; Achterhold, Klaus; Gleich, Bernhard; Dierolf, Martin; Pfeiffer, Franz; Moser, Tobias; Salditt, Tim

    2018-03-21

    We demonstrate that phase retrieval and tomographic imaging at the organ level of small animals can be advantageously carried out using the monochromatic radiation emitted by a compact x-ray light source, without further optical elements apart from source and detector. This approach allows to carry out microtomography experiments which - due to the large performance gap with respect to conventional laboratory instruments - so far were usually limited to synchrotron sources. We demonstrate the potential by mapping the functional soft tissue within the guinea pig and marmoset cochlea, including in the latter case an electrical cochlear implant. We show how 3d microanatomical studies without dissection or microscopic imaging can enhance future research on cochlear implants.

  17. Studies of beam injection with a compensated bump and uncompensated bump in a synchrotron

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Akbar Fakhri, Ali; Prajapati, S. K.; Ghodke, A. D.

    2013-08-15

    Synchrotron radiation sources Indus-1 and Indus-2 have a synchrotron as the common injector. A three kicker compensated bump injection scheme was employed for beam injection into this synchrotron. The stored beam current in the synchrotron is higher, when all the three kickers are operated at the same current than when kickers are operated at currents required to generate compensated bump. Beam dynamics studies have been done to understand why this happens. Theoretical studies indicate that higher stored current in the later case is attributed to smaller residual oscillations of injected beam. These studies also reveal that if the angle ofmore » the injected beam during beam injection is kept varying, the performance could be further improved. This is experimentally confirmed by injecting the beam on rising part of the injection septum magnet current pulse.« less

  18. Intrinsic and extrinsic motivational orientations in the competitive context: an examination of person-situation interactions.

    PubMed

    Abuhamdeh, Sami; Csikszentmihalyi, Mihaly

    2009-10-01

    The current study examined Intrinsic Motivation Orientation and Extrinsic Motivation Orientation (Work Preference Inventory; Amabile, Hill, Hennessey, & Tighe, 1994) as potential trait-level moderators of the way Internet chess players responded to the intrinsic and extrinsic rewards of the chess games they played. On the basis of the defining characteristics of these 2 types of motivational orientations, we predicted that (a) Intrinsic Motivation Orientation would be associated with a stronger curvilinear relationship between challenge and enjoyment and (b) Extrinsic Motivation Orientation would be associated with a heightened affective responsivity to competitive outcome (i.e., winning vs. losing). Results supported the predictions. Implications of the findings are discussed.

  19. Mono-energy coronary angiography with a compact light source

    NASA Astrophysics Data System (ADS)

    Eggl, Elena; Mechlem, Korbinian; Braig, Eva; Kulpe, Stephanie; Dierolf, Martin; Günther, Benedikt; Achterhold, Klaus; Herzen, Julia; Gleich, Bernhard; Rummeny, Ernst; Noël, Peter B.; Pfeiffer, Franz; Muenzel, Daniela

    2017-03-01

    While conventional x-ray tube sources reliably provide high-power x-ray beams for everyday clinical practice, the broad spectra that are inherent to these sources compromise the diagnostic image quality. For a monochromatic x-ray source on the other hand, the x-ray energy can be adjusted to optimal conditions with respect to contrast and dose. However, large-scale synchrotron sources impose high spatial and financial demands, making them unsuitable for clinical practice. During the last decades, research has brought up compact synchrotron sources based on inverse Compton scattering, which deliver a highly brilliant, quasi-monochromatic, tunable x-ray beam, yet fitting into a standard laboratory. One application that could benefit from the invention of these sources in clinical practice is coronary angiography. Being an important and frequently applied diagnostic tool, a high number of complications in angiography, such as renal failure, allergic reaction, or hyperthyroidism, are caused by the large amount of iodine-based contrast agent that is required for achieving sufficient image contrast. Here we demonstrate monochromatic angiography of a porcine heart acquired at the MuCLS, the first compact synchrotron source. By means of a simulation, the CNR in a coronary angiography image achieved with the quasi-mono-energetic MuCLS spectrum is analyzed and compared to a conventional x-ray-tube spectrum. The results imply that the improved CNR achieved with a quasi-monochromatic spectrum can allow for a significant reduction of iodine contrast material.

  20. 6th international conference on biophysics and synchrotron radiation. Program/Abstracts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pittroff, Connie; Strasser, Susan Barr

    1999-08-03

    This STI product consists of the Program/Abstracts book that was prepared for the participants in the Sixth International Conference on Biophysics and Synchrotron Radiation that was held August 4-8, 1998, at the Advanced Photon Source, Argonne National Laboratory. This book contains the full conference program and abstracts of the scientific presentations.

  1. An X-ray beam position monitor based on the photoluminescence of helium gas

    NASA Astrophysics Data System (ADS)

    Revesz, Peter; White, Jeffrey A.

    2005-03-01

    A new method for white beam position monitoring for both bend magnet and wiggler synchrotron X-ray radiation has been developed. This method utilizes visible light luminescence generated as a result of ionization by the intense X-ray flux. In video beam position monitors (VBPMs), the luminescence of helium gas at atmospheric pressure is observed through a view port using a CCD camera next to the beam line. The beam position, profile, integrated intensity and FWHM are calculated from the distribution of luminescence intensity in each captured image by custom software. Misalignment of upstream apertures changes the image profile making VBPMs helpful for initial alignment of upstream beam line components. VBPMs can thus provide more information about the X-ray beam than most beam position monitors (BPMs). A beam position calibration procedure, employing a tilted plane-parallel glass plate placed in front of the camera lens, has also been developed. The accuracy of the VBPM system was measured during a bench-top experiment to be better than 1 μm. The He-luminescence-based VBPM system has been operative on three CHESS beam lines (F hard-bend and wiggler, A-line wiggler and G-line wiggler) for about a year. The beam positions are converted to analog voltages and used as feedback signals for beam stabilization. In our paper we discuss details of VBPM construction and describe further results of its performance.

  2. Additional Spitzer IRS Spectroscopy of Three Intermediate Polars: The Detection of a Mid-infrared Synchrotron Flare from V1223 Sagittarii

    NASA Astrophysics Data System (ADS)

    Harrison, Thomas E.; Bornak, Jillian; Rupen, Michael P.; Howell, Steve B.

    2010-02-01

    We present new Spitzer Infrared Spectrograph (IRS) observations of three intermediate polars: V1223 Sgr, EX Hya, and V603 Aql. We detected a strong, fading flare event from V1223 Sgr. During this event, the flux declined by a factor of 13 in 30 minutes. Given the similarity in the slope of its mid-infrared spectrum during this event to that of AE Aqr, we suggest that this event was caused by transient synchrotron emission. Thus, V1223 Sgr becomes the third cataclysmic variable known to be a synchrotron source. We were unable to confirm the mid-infrared excess noted by Harrison et al. (Paper I) for EX Hya, suggesting that this object is either not a synchrotron source, or is slightly variable. Due to a very high background, V603 Aql was not detected in the long-wavelength regions accessible to the IRS. Given the recent detection of SS Cygni at radio wavelengths during outburst, we extract archival Spitzer IRS spectra for this source obtained during two successive maxima. These spectra do not show a strong excess, but without simultaneous data at shorter wavelengths, it is not possible to determine whether there is any contribution to the mid-infrared fluxes from a synchrotron jet. Includes observations obtained at the Gemini Observatory, which is operated by the Association of Universities for Research in Astronomy, Inc., under a cooperative agreement with the NSF on behalf of the Gemini partnership: the National Science Foundation (United States), the Science and Technology Facilities Council (United Kingdom), the National Research Council (Canada), CONICYT (Chile), the Australian Research Council (Australia), Ministério da Ciência e Tecnologia (Brazil), and Ministerio de Ciencia, Tecnología e Innovación Productiva (Argentina).

  3. Omega Dante soft x-ray power diagnostic component calibration at the National Synchrotron Light Source

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Campbell, K.M.; Weber, F.A.; Dewald, E.L.

    2004-10-01

    The Dante soft x-ray spectrometer, installed on the Omega laser facility at the Laboratory for Laser Energetics, University of Rochester, is a 12-channel filter-edge defined soft x-ray power diagnostic. It is used to measure the spectrally resolved, absolute flux from direct drive, indirect drive (hohlraums) and other plasma sources. Dante component calibration efforts using two beam lines, U3C (50 eV-1 keV) and X8A (1-6 keV) at the National Synchrotron Light Source have been implemented to improve the accuracy of these measurements. We have calibrated metallic vacuum x-ray diodes, mirrors and filters.

  4. A smog chamber study coupling a photoionization aerosol electron/ion spectrometer to VUV synchrotron radiation: organic and inorganic-organic mixed aerosol analysis

    NASA Astrophysics Data System (ADS)

    Baeza-Romero, María Teresa; Gaie-Levrel, Francois; Mahjoub, Ahmed; López-Arza, Vicente; Garcia, Gustavo A.; Nahon, Laurent

    2016-07-01

    A reaction chamber was coupled to a photoionization aerosol time-of-flight mass spectrometer based on an electron/ion coincidence scheme and applied for on-line analysis of organic and inorganic-organic mixed aerosols using synchrotron tunable vacuum ultraviolet (VUV) photons as the ionization source. In this proof of principle study, both aerosol and gas phase were detected simultaneously but could be differentiated. Present results and perspectives for improvement for this set-up are shown in the study of ozonolysis ([O3] = 0.13-3 ppm) of α-pinene (2-3 ppm), and the uptake of glyoxal upon ammonium sulphate. In this work the ozone concentration was monitored in real time, together with the particle size distributions and chemical composition, the latter taking advantage of the coincidence spectrometer and the tuneability of the synchrotron radiation as a soft VUV ionization source.

  5. High-energy synchrotron X-ray radiography of shock-compressed materials

    NASA Astrophysics Data System (ADS)

    Rutherford, Michael E.; Chapman, David J.; Collinson, Mark A.; Jones, David R.; Music, Jasmina; Stafford, Samuel J. P.; Tear, Gareth R.; White, Thomas G.; Winters, John B. R.; Drakopoulos, Michael; Eakins, Daniel E.

    2015-06-01

    This presentation will discuss the development and application of a high-energy (50 to 250 keV) synchrotron X-ray imaging method to study shock-compressed, high-Z samples at Beamline I12 at the Diamond Light Source synchrotron (Rutherford-Appleton Laboratory, UK). Shock waves are driven into materials using a portable, single-stage gas gun designed by the Institute of Shock Physics. Following plate impact, material deformation is probed in-situ by white-beam X-ray radiography and complimentary velocimetry diagnostics. The high energies, large beam size (13 x 13 mm), and appreciable sample volumes (~ 1 cm3) viable for study at Beamline I12 compliment existing in-house pulsed X-ray capabilities and studies at the Dynamic Compression Sector. The authors gratefully acknowledge the ongoing support of Imperial College London, EPSRC, STFC and the Diamond Light Source, and AWE Plc.

  6. National Synchrotron Light Source II storage ring vacuum systems

    DOE PAGES

    Hseuh, Hsiao-Chaun; Hetzel, Charles; Leng, Shuwei; ...

    2016-04-05

    The National Synchrotron Light Source II, completed in 2014, is a 3-GeV synchrotron radiation (SR) facility at Brookhaven National Laboratory and has been in steady operation since. With a design electron current of 500 mA and subnanometer radians horizontal emittance, this 792-m circumference storage ring is providing the highest flux and brightness x-ray beam for SR users. Also, the majority of the storage ring vacuum chambers are made of extruded aluminium. Chamber sections are interconnected using low-impedance radiofrequency shielded bellows. SR from the bending magnets is intercepted by water-cooled compact photon absorbers resided in the storage ring chambers. Finally, thismore » paper presents the design of the storage ring vacuum system, the fabrication of vacuum chambers and other hardware, the installation, the commissioning, and the continuing beam conditioning of the vacuum systems.« less

  7. Holographic illuminator for synchrotron-based projection lithography systems

    DOEpatents

    Naulleau, Patrick P.

    2005-08-09

    The effective coherence of a synchrotron beam line can be tailored to projection lithography requirements by employing a moving holographic diffuser and a stationary low-cost spherical mirror. The invention is particularly suited for use in an illuminator device for an optical image processing system requiring partially coherent illumination. The illuminator includes: (1) a synchrotron source of coherent or partially coherent radiation which has an intrinsic coherence that is higher than the desired coherence, (2) a holographic diffuser having a surface that receives incident radiation from said source, (3) means for translating the surface of the holographic diffuser in two dimensions along a plane that is parallel to the surface of the holographic diffuser wherein the rate of the motion is fast relative to integration time of said image processing system; and (4) a condenser optic that re-images the surface of the holographic diffuser to the entrance plane of said image processing system.

  8. Pink-beam serial crystallography

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Meents, A.; Wiedorn, M. O.; Srajer, V.

    Serial X-ray crystallography allows macromolecular structure determination at both X-ray free electron lasers (XFELs) and, more recently, synchrotron sources. The time resolution for serial synchrotron crystallography experiments has been limited to millisecond timescales with monochromatic beams. The polychromatic, “pink”, beam provides a more than two orders of magnitude increased photon flux and hence allows accessing much shorter timescales in diffraction experiments at synchrotron sources. Here we report the structure determination of two different protein samples by merging pink-beam diffraction patterns from many crystals, each collected with a single 100 ps X-ray pulse exposure per crystal using a setup optimized formore » very low scattering background. In contrast to experiments with monochromatic radiation, data from only 50 crystals were required to obtain complete datasets. The high quality of the diffraction data highlights the potential of this method for studying irreversible reactions at sub-microsecond timescales using high-brightness X-ray facilities.« less

  9. Pink-beam serial crystallography

    DOE PAGES

    Meents, A.; Wiedorn, M. O.; Srajer, V.; ...

    2017-11-03

    Serial X-ray crystallography allows macromolecular structure determination at both X-ray free electron lasers (XFELs) and, more recently, synchrotron sources. The time resolution for serial synchrotron crystallography experiments has been limited to millisecond timescales with monochromatic beams. The polychromatic, “pink”, beam provides a more than two orders of magnitude increased photon flux and hence allows accessing much shorter timescales in diffraction experiments at synchrotron sources. Here we report the structure determination of two different protein samples by merging pink-beam diffraction patterns from many crystals, each collected with a single 100 ps X-ray pulse exposure per crystal using a setup optimized formore » very low scattering background. In contrast to experiments with monochromatic radiation, data from only 50 crystals were required to obtain complete datasets. The high quality of the diffraction data highlights the potential of this method for studying irreversible reactions at sub-microsecond timescales using high-brightness X-ray facilities.« less

  10. Synchrotron-based far-infrared spectroscopy of furan: Rotational analysis of the ν 14 , ν 11 , ν 18 and ν 19 vibrational levels

    NASA Astrophysics Data System (ADS)

    Tokaryk, D. W.; Culligan, S. D.; Billinghurst, B. E.; van Wijngaarden, J. A.

    2011-11-01

    Four vibrational levels of the five-membered ring molecule furan (C 4H 4O) have been rotationally analyzed from far-infrared Fourier transform spectra obtained at the Canadian Light Source synchrotron. We found that the low-lying ν14 and ν11 levels at 602.9 and 599.6 cm -1 interact through a second-order Coriolis resonance. This perturbation was characterized through a coupled analysis of the ν14 and ν18 fundamental spectra and the ν18- ν11 band. The ν19 fundamental spectrum was analyzed as well, and the data for all observed bands were combined with previously reported microwave transitions to produce the final fit. The spectra are an excellent demonstration of the high quality of data that can be obtained when far-infrared synchrotron radiation is used as the radiation source in Fourier transform spectroscopy experiments.

  11. Reducing Symptom Distress in Patients With Advanced Cancer Using an e-Alert System for Caregivers: Pooled Analysis of Two Randomized Clinical Trials

    PubMed Central

    DuBenske, Lori L; Atwood, Amy K; Chih, Ming-Yuan; Johnson, Roberta A; McTavish, Fiona; Quanbeck, Andrew; Brown, Roger L; Cleary, James F; Shah, Dhavan

    2017-01-01

    Background Symptom distress in patients toward the end of life can change rapidly. Family caregivers have the potential to help patients manage those symptoms, as well as their own stress, if they are equipped with the proper resources. Electronic health (eHealth) systems may be able to provide those resources. Very sick patients may not be able to use such systems themselves to report their symptoms but family caregivers could. Objective The aim of this paper was to assess the effects on cancer patient symptom distress of an eHealth system that alerts clinicians to significant changes in the patient’s symptoms, as reported by a family caregiver. Methods A pooled analysis from two randomized clinical trials (NCT00214162 and NCT00365963) compared outcomes at 12 months for two unblinded groups: a control group (Comprehensive Health Enhancement Support System [CHESS]-Only) that gave caregivers access to CHESS, an online support system, and an experimental group (CHESS+CR [Clinician Report]), which also had CHESS but with a CR that automatically alerted clinicians if symptoms exceeded a predetermined threshold of severity. Participants were dyads (n=235) of patients with advanced lung, breast, or prostate cancer and their respective family caregivers from 5 oncology clinics in the United States of America. The proportion of improved patient threshold symptoms was compared between groups using area-under-the-curve analysis and binomial proportion tests. The proportion of threshold symptoms out of all reported symptoms was also examined. Results When severe caregiver-reported symptoms were shared with clinicians, the symptoms were more likely to be subsequently reported as improved than when the symptoms were not shared with clinicians (P<.001). Fewer symptom reports were completed in the group of caregivers whose reports went to clinicians than in the CHESS-Only group (P<.001), perhaps because caregivers, knowing their reports might be sent to a doctor, feared they might be bothering the clinician. Conclusions This study suggests that an eHealth system designed for caregivers that alerts clinicians to worrisome changes in patient health status may lead to reduced patient distress. Trial Registration Clinicaltrials.gov NCT00214162; https://clinicaltrials.gov/ct2/show/NCT00214162 (Archived by WebCite at http://www.webcitation.org/6nmgdGfuD) and Clinicaltrials.gov NCT00365963; https://clinicaltrials.gov/ct2/show/NCT00365963 (Archived by WebCite at http://www.webcitation.org/6nmh0U8VP) PMID:29138131

  12. Variable Magnification With Kirkpatrick-Baez Optics for Synchrotron X-Ray Microscopy

    PubMed Central

    Jach, Terrence; Bakulin, Alex S.; Durbin, Stephen M.; Pedulla, Joseph; Macrander, Albert

    2006-01-01

    We describe the distinction between the operation of a short focal length x-ray microscope forming a real image with a laboratory source (convergent illumination) and with a highly collimated intense beam from a synchrotron light source (Köhler illumination). We demonstrate the distinction with a Kirkpatrick-Baez microscope consisting of short focal length multilayer mirrors operating at an energy of 8 keV. In addition to realizing improvements in the resolution of the optics, the synchrotron radiation microscope is not limited to the usual single magnification at a fixed image plane. Higher magnification images are produced by projection in the limit of geometrical optics with a collimated beam. However, in distinction to the common method of placing the sample behind the optical source of a diverging beam, we describe the situation in which the sample is located in the collimated beam before the optical element. The ultimate limits of this magnification result from diffraction by the specimen and are determined by the sample position relative to the focal point of the optic. We present criteria by which the diffraction is minimized. PMID:27274930

  13. X-Ray Data Booklet

    Science.gov Websites

    X-RAY DATA BOOKLET Center for X-ray Optics and Advanced Light Source Lawrence Berkeley National Laboratory Introduction X-Ray Properties of Elements Electron Binding Energies X-Ray Energy Emission Energies Table of X-Ray Properties Synchrotron Radiation Characteristics of Synchrotron Radiation History of X

  14. Tests of monolithic active pixel sensors at national synchrotron light source

    NASA Astrophysics Data System (ADS)

    Deptuch, G.; Besson, A.; Carini, G. A.; Siddons, D. P.; Szelezniak, M.; Winter, M.

    2007-01-01

    The paper discusses basic characterization of Monolithic Active Pixel Sensors (MAPS) carried out at the X12A beam-line at National Synchrotron Light Source (NSLS), Upton, NY, USA. The tested device was a MIMOSA V (MV) chip, back-thinned down to the epitaxial layer. This 1M pixels device features a pixel size of 17×17 μm2 and was designed in a 0.6 μm CMOS process. The X-ray beam energies used range from 5 to 12 keV. Examples of direct X-ray imaging capabilities are presented.

  15. High-pressure Experimental Studies on Geo-liquids Using Synchrotron Radiation at the Advanced Photon Source

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Yanbin; Shen, Guoyin

    2014-12-23

    Here, we review recent progress in studying silicate, carbonate, and metallic liquids of geological and geophysical importance at high pressure and temperature, using the large-volume high-pressure devices at the third-generation synchrotron facility of the Advanced Photon Source, Argonne National Laboratory. These integrated high-pressure facilities now offer a unique combination of experimental techniques that allow researchers to investigate structure, density, elasticity, viscosity, and interfacial tension of geo-liquids under high pressure, in a coordinated and systematic fashion. Moreover, we describe experimental techniques, along with scientific highlights. Future developments are also discussed.

  16. Metrology laboratory requirements for third-generation synchrotron radiation sources

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Takacs, P.Z.; Quian, Shinan

    1997-11-01

    New third-generation synchrotron radiation sources that are now, or will soon, come on line will need to decide how to handle the testing of optical components delivered for use in their beam lines. In many cases it is desirable to establish an in-house metrology laboratory to do the work. We review the history behind the formation of the Optical Metrology Laboratory at Brookhaven National Laboratory and the rationale for its continued existence. We offer suggestions to those who may be contemplating setting up similar facilities, based on our experiences over the past two decades.

  17. Facilities for small-molecule crystallography at synchrotron sources.

    PubMed

    Barnett, Sarah A; Nowell, Harriott; Warren, Mark R; Wilcox, Andrian; Allan, David R

    2016-01-01

    Although macromolecular crystallography is a widely supported technique at synchrotron radiation facilities throughout the world, there are, in comparison, only very few beamlines dedicated to small-molecule crystallography. This limited provision is despite the increasing demand for beamtime from the chemical crystallography community and the ever greater overlap between systems that can be classed as either small macromolecules or large small molecules. In this article, a very brief overview of beamlines that support small-molecule single-crystal diffraction techniques will be given along with a more detailed description of beamline I19, a dedicated facility for small-molecule crystallography at Diamond Light Source.

  18. Microscope using an x-ray tube and a bubble compound refractive lens

    NASA Astrophysics Data System (ADS)

    Piestrup, M. A.; Gary, C. K.; Park, H.; Harris, J. L.; Cremer, J. T.; Pantell, R. H.; Dudchik, Y. I.; Kolchevsky, N. N.; Komarov, F. F.

    2005-03-01

    We present x-ray images of grid meshes and biological material obtained using an unfiltered x-ray tube and a compound refractive lens composed of microbubbles embedded in epoxy inside a glass capillary. Images obtained using this apparatus are compared with those using a synchrotron source and the same lens. We find that the field of view is larger than that obtained using the synchrotron source, whereas the contrast and resolution are reduced. Geometrical distortion around the edges of the field of view is also reduced. The experiments demonstrate the usefulness of the apparatus in a modest laboratory setting.

  19. High Resolution Far-Infrared Spectra of Thiophosgene with a Synchrotron Source: The ν2 and ν4 Bands Near 500 cm-1

    NASA Astrophysics Data System (ADS)

    McKellar, A. R. W.; Billinghurst, B. E.

    2010-02-01

    Thiophosgene (Cl2CS) is a favorite model system for studies of vibrational dynamics. But there are no previous rotationally-resolved infrared studies because the spectra are very congested due to its (relatively) large mass and multiple isotopic species. Here we report a detailed gas-phase study of the ν2 (˜504 cm-1) and ν4 (˜471 cm-1) fundamental bands, based on spectra obtained at the Canadian Light Source far-infrared beamline using synchrotron radiation and a Bruker IFS125 FT spectrometer.

  20. Reconnaissance blind multi-chess: an experimentation platform for ISR sensor fusion and resource management

    NASA Astrophysics Data System (ADS)

    Newman, Andrew J.; Richardson, Casey L.; Kain, Sean M.; Stankiewicz, Paul G.; Guseman, Paul R.; Schreurs, Blake A.; Dunne, Jeffrey A.

    2016-05-01

    This paper introduces the game of reconnaissance blind multi-chess (RBMC) as a paradigm and test bed for understanding and experimenting with autonomous decision making under uncertainty and in particular managing a network of heterogeneous Intelligence, Surveillance and Reconnaissance (ISR) sensors to maintain situational awareness informing tactical and strategic decision making. The intent is for RBMC to serve as a common reference or challenge problem in fusion and resource management of heterogeneous sensor ensembles across diverse mission areas. We have defined a basic rule set and a framework for creating more complex versions, developed a web-based software realization to serve as an experimentation platform, and developed some initial machine intelligence approaches to playing it.

  1. jsc2017e137337 - At the Cosmonaut Hotel crew quarters in Baikonur, Kazakhstan, Expedition 54-55 prime crewmember Scott Tingle of NASA plays a game of chess Dec. 11 during a break in his pre-launch training. Tingle, Norishige Kanai of the Japan Aerospace E

    NASA Image and Video Library

    2017-12-11

    jsc2017e137337 - At the Cosmonaut Hotel crew quarters in Baikonur, Kazakhstan, Expedition 54-55 prime crewmember Scott Tingle of NASA plays a game of chess Dec. 11 during a break in his pre-launch training. Tingle, Norishige Kanai of the Japan Aerospace Exploration Agency (JAXA) and Anton Shkaplerov of the Russian Federal Space Agency (Roscosmos) will launch Dec. 17 on the Soyuz MS-07 spacecraft from the Baikonur Cosmodrome for a five month mission on the International Space Station...Andrey Shelepin / Gagarin Cosmonaut Training Center.

  2. Hopelessness is associated with decreased heart rate variability during championship chess games.

    PubMed

    Schwarz, Alfons M; Schächinger, Hartmut; Adler, Rolf H; Goetz, Stefan M

    2003-01-01

    Clinical observations suggest that negative affects such as helplessness/hopelessness (HE/HO) may induce autonomic duration; affects were assessed for every move after reconstruction of the games. In all games compiled, 18 situation of intense confidence/optimism and 20 of intense helplessness/hopelessness were observed. Intense affects of HE/HO were associated with decreasing HF-HRV (Fisher exact test, p =.003), increasing "nervousness" (p =.0005), decreasing "optimism" (p =.0005), and decreasing "calmness" (p =.0005). Investigation of championship chess game players with an ELO strength > or = 2300 in a natural field setting revealed increasing HE/HO being associated with reduced HF-HRV suggestive of vagal withdrawal. Thus, our data may help link negative mood states, autonomic nervous system disturbances, and cardiac events.

  3. Molecular computation: RNA solutions to chess problems.

    PubMed

    Faulhammer, D; Cukras, A R; Lipton, R J; Landweber, L F

    2000-02-15

    We have expanded the field of "DNA computers" to RNA and present a general approach for the solution of satisfiability problems. As an example, we consider a variant of the "Knight problem," which asks generally what configurations of knights can one place on an n x n chess board such that no knight is attacking any other knight on the board. Using specific ribonuclease digestion to manipulate strands of a 10-bit binary RNA library, we developed a molecular algorithm and applied it to a 3 x 3 chessboard as a 9-bit instance of this problem. Here, the nine spaces on the board correspond to nine "bits" or placeholders in a combinatorial RNA library. We recovered a set of "winning" molecules that describe solutions to this problem.

  4. Depleted uranium investigation at missile impact sites in White Sands Missile Range

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Van Etten, D.M.; Purtymun, W.D.

    1994-01-01

    An investigation for residual depleted uranium was conducted at Pershing missile impact sites on the White Sands Missile Range. Subsurface core soil samples were taken at Chess, Salt Target, and Mine Impact Sites. A sampling pump was installed in a monitoring well at Site 65 where a Pershing earth penetrator was not recovered. Pumping tests and water samples were taken at this site. Chess Site, located in a gypsum flat, was the only location showing elevated levels of depleted uranium in the subsurface soil or perched groundwater. Small fragments can still be found on the surface of the impact sites.more » The seasonal flooding and near surface water has aided in the movement of surface fragments.« less

  5. RELATIVISTIC THOMSON SCATTERING EXPERIMENT AT BNL - STATUS REPORT.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    POGORELSKY,I.V.; BEN ZVI,I.; KUSCHE,K.

    2001-12-03

    1.7 x 10{sup 8} x-ray photons per 3.5 ps pulse have been produced in Thomson scattering by focusing CO{sub 2} laser pulse on counter-propagating relativistic electron beam. We explore a possibility of further enhancement of process efficiency by propagating both beams in a plasma capillary. Conventional synchrotron light sources based on using giga-electron-volt electron synchrotron accelerators and magnetic wigglers generate x-ray radiation for versatile application in multi-disciplinary research. An intense laser beam causes relativistic electron oscillations similar to a wiggler. However, because the laser wavelength is thousand times shorter than a wiggler period, very moderate electron energy is needed tomore » produce hard x-rays via Thomson scattering. This allows using relatively compact mega-electron-volt linear accelerators instead of giga-electron-volt synchrotrons. Another important advantage of Thomson sources is a possibility to generate femtosecond x-ray pulses whereas conventional synchrotron sources have typically {approx}300 ps pulse duration. This promises to revolutionize x-ray research in chemistry, physics, and biology expanding it to ultra-fast processes. Thomson sources do not compete in repetition rate and average intensity with conventional light sources that operate at the megahertz frequency. However, Thomson sources have a potential to produce much higher photon numbers per pulse. This may allow developing a single shot exposure important for structural analysis of live biological objects. The BNL Thomson source is a user's experiment conducted at the Accelerator Test Facility since 1998 by an international collaboration in High Energy Physics. Since inception, the ATF source produces the record peak x-ray yield, intensity and brightness among other similar proof-of-principle demonstrations attempted elsewhere. Note that this result is achieved with a moderate laser power of 15 GW. A key to this achievement is in choosing right apparatus and efficient interaction geometry. We use a CO{sub 2} laser that delivers 10 times more photons per unit energy than the 1-{micro}m laser, a high-brightness linac, and the most energy-efficient backscattering interaction geometry. The purpose of this report is to give an update on new results obtained during this year and our near-term plans.« less

  6. Towards a 4{sup th} generation storage ring at the Canadian Light Source

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dallin, Les; Wurtz, Ward

    2016-07-27

    Demands from beamline scientists for more brilliant sources of synchrotron radiation have resulted in the emergence of 4{sup th} generation (diffraction-limited) storage rings. The practical development of the multi-bend achromat (MBA) concept by MAX IV lab has spurred many synchrotron light sources around the world to develop similar machines. For existing facilities two options are available: upgrading existing machines or building a new structure. The Canadian Light Source (CLS) has explored both options. For a new low emittance source in the existing CLS tunnel a decrease in electron energy would be required. A machine similar to the ALS upgrade couldmore » be contemplated. To achieve low emittance at our present energy of 2.9 GeV a new storage ring is desirable. Several options have been investigated. These designs use extremely strong focusing magnets to achieve extremely low emittances in compact lattice achromats.« less

  7. EMITTING ELECTRONS AND SOURCE ACTIVITY IN MARKARIAN 501

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mankuzhiyil, Nijil; Ansoldi, Stefano; Persic, Massimo

    2012-07-10

    We study the variation of the broadband spectral energy distribution (SED) of the BL Lac object Mrk 501 as a function of source activity, from quiescent to flaring. Through {chi}{sup 2}-minimization we model eight simultaneous SED data sets with a one-zone synchrotron self-Compton (SSC) model, and examine how model parameters vary with source activity. The emerging variability pattern of Mrk 501 is complex, with the Compton component arising from {gamma}-e scatterings that sometimes are (mostly) Thomson and sometimes (mostly) extreme Klein-Nishina. This can be seen from the variation of the Compton to synchrotron peak distance according to source state. Themore » underlying electron spectra are faint/soft in quiescent states and bright/hard in flaring states. A comparison with Mrk 421 suggests that the typical values of the SSC parameters are different in the two sources: however, in both jets the energy density is particle-dominated in all states.« less

  8. Beam measurement of the high frequency impedance sources with long bunches in the CERN Super Proton Synchrotron

    NASA Astrophysics Data System (ADS)

    Lasheen, A.; Argyropoulos, T.; Bohl, T.; Esteban Müller, J. F.; Timko, H.; Shaposhnikova, E.

    2018-03-01

    Microwave instability in the Super Proton Synchrotron (SPS) at CERN is one of the main limitations to reach the requirements for the High Luminosity-LHC project (increased beam intensity by a factor 2). To identify the impedance source responsible of the instability, beam measurements were carried out to probe the SPS impedance. The method presented in this paper relies on measurements of the unstable spectra of single bunches, injected in the SPS with the rf voltage switched off. The modulation of the bunch profile gives information about the main impedance sources driving microwave instability, and is compared to particle simulations using the SPS impedance model to identify the most important contributions. This allowed us to identify the vacuum flanges as the main impedance source for microwave instability in the SPS, and to evaluate possible missing impedance sources.

  9. Translation of Atherosclerotic Plaque Phase-Contrast CT Imaging from Synchrotron Radiation to a Conventional Lab-Based X-Ray Source

    PubMed Central

    Saam, Tobias; Herzen, Julia; Hetterich, Holger; Fill, Sandra; Willner, Marian; Stockmar, Marco; Achterhold, Klaus; Zanette, Irene; Weitkamp, Timm; Schüller, Ulrich; Auweter, Sigrid; Adam-Neumair, Silvia; Nikolaou, Konstantin; Reiser, Maximilian F.; Pfeiffer, Franz; Bamberg, Fabian

    2013-01-01

    Objectives Phase-contrast imaging is a novel X-ray based technique that provides enhanced soft tissue contrast. The aim of this study was to evaluate the feasibility of visualizing human carotid arteries by grating-based phase-contrast tomography (PC-CT) at two different experimental set-ups: (i) applying synchrotron radiation and (ii) using a conventional X-ray tube. Materials and Methods Five ex-vivo carotid artery specimens were examined with PC-CT either at the European Synchrotron Radiation Facility using a monochromatic X-ray beam (2 specimens; 23 keV; pixel size 5.4 µm), or at a laboratory set-up on a conventional X-ray tube (3 specimens; 35-40 kVp; 70 mA; pixel size 100 µm). Tomographic images were reconstructed and compared to histopathology. Two independent readers determined vessel dimensions and one reader determined signal-to-noise ratios (SNR) between PC-CT and absorption images. Results In total, 51 sections were included in the analysis. Images from both set-ups provided sufficient contrast to differentiate individual vessel layers. All PCI-based measurements strongly predicted but significantly overestimated lumen, intima and vessel wall area for both the synchrotron and the laboratory-based measurements as compared with histology (all p<0.001 with slope >0.53 per mm2, 95%-CI: 0.35 to 0.70). Although synchrotron-based images were characterized by higher SNRs than laboratory-based images; both PC-CT set-ups had superior SNRs compared to corresponding conventional absorption-based images (p<0.001). Inter-reader reproducibility was excellent (ICCs >0.98 and >0.84 for synchrotron and for laboratory-based measurements; respectively). Conclusion Experimental PC-CT of carotid specimens is feasible with both synchrotron and conventional X-ray sources, producing high-resolution images suitable for vessel characterization and atherosclerosis research. PMID:24039969

  10. Operation of the Australian Store.Synchrotron for macromolecular crystallography

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Meyer, Grischa R.; Aragão, David; Mudie, Nathan J.

    2014-10-01

    The Store.Synchrotron service, a fully functional, cloud computing-based solution to raw X-ray data archiving and dissemination at the Australian Synchrotron, is described. The Store.Synchrotron service, a fully functional, cloud computing-based solution to raw X-ray data archiving and dissemination at the Australian Synchrotron, is described. The service automatically receives and archives raw diffraction data, related metadata and preliminary results of automated data-processing workflows. Data are able to be shared with collaborators and opened to the public. In the nine months since its deployment in August 2013, the service has handled over 22.4 TB of raw data (∼1.7 million diffraction images). Severalmore » real examples from the Australian crystallographic community are described that illustrate the advantages of the approach, which include real-time online data access and fully redundant, secure storage. Discoveries in biological sciences increasingly require multidisciplinary approaches. With this in mind, Store.Synchrotron has been developed as a component within a greater service that can combine data from other instruments at the Australian Synchrotron, as well as instruments at the Australian neutron source ANSTO. It is therefore envisaged that this will serve as a model implementation of raw data archiving and dissemination within the structural biology research community.« less

  11. Simulations of X-ray diffraction of shock-compressed single-crystal tantalum with synchrotron undulator sources.

    PubMed

    Tang, M X; Zhang, Y Y; E, J C; Luo, S N

    2018-05-01

    Polychromatic synchrotron undulator X-ray sources are useful for ultrafast single-crystal diffraction under shock compression. Here, simulations of X-ray diffraction of shock-compressed single-crystal tantalum with realistic undulator sources are reported, based on large-scale molecular dynamics simulations. Purely elastic deformation, elastic-plastic two-wave structure, and severe plastic deformation under different impact velocities are explored, as well as an edge release case. Transmission-mode diffraction simulations consider crystallographic orientation, loading direction, incident beam direction, X-ray spectrum bandwidth and realistic detector size. Diffraction patterns and reciprocal space nodes are obtained from atomic configurations for different loading (elastic and plastic) and detection conditions, and interpretation of the diffraction patterns is discussed.

  12. Neutron and Synchrotron Radiation Studies for Designer Materials, Sustainable Energy and Healthy Lives

    NASA Astrophysics Data System (ADS)

    Gibson, J. Murray

    2009-05-01

    Probably the most prolific use of large accelerators today is in the creation of bright beams of x-ray photons or neutrons. The number of scientific users of such sources in the US alone is approaching 10,000. I will describe the some of the major applications of synchrotron and neutron radiation and their impact on society. If you have AIDS, need a better IPOD or a more efficient car, or want to clean up a superfund site, you are benefitting from these accelerators. The design of new materials is becoming more and more dependent on structural information from these sources. I will identify the trends in applications which are demanding new sources with greater capabilities.

  13. Simulations of X-ray diffraction of shock-compressed single-crystal tantalum with synchrotron undulator sources

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tang, M. X.; Zhang, Y. Y.; E, J. C.

    Polychromatic synchrotron undulator X-ray sources are useful for ultrafast single-crystal diffraction under shock compression. Here, simulations of X-ray diffraction of shock-compressed single-crystal tantalum with realistic undulator sources are reported, based on large-scale molecular dynamics simulations. Purely elastic deformation, elastic–plastic two-wave structure, and severe plastic deformation under different impact velocities are explored, as well as an edge release case. Transmission-mode diffraction simulations consider crystallographic orientation, loading direction, incident beam direction, X-ray spectrum bandwidth and realistic detector size. Diffraction patterns and reciprocal space nodes are obtained from atomic configurations for different loading (elastic and plastic) and detection conditions, and interpretation of themore » diffraction patterns is discussed.« less

  14. Probing Combustion Chemistry in a Miniature Shock Tube with Synchrotron VUV Photo Ionization Mass Spectrometry

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lynch, Patrick T.; Troy, Tyler P.; Ahmed, Musahid

    2015-01-29

    Tunable synchrotron-sourced photoionization time-of-flight mass spectrometry (PI-TOF-MS) is an important technique in combustion chemistry, complementing lab-scale electron impact and laser photoionization studies for a wide variety of reactors, typically at low pressure. For high-temperature and high-pressure chemical kinetics studies, the shock tube is the reactor of choice. Extending the benefits of shock tube/TOF-MS research to include synchrotron sourced PI-TOF-MS required a radical reconception of the shock tube. An automated, miniature, high-repetition-rate shock tube was developed and can be used to study high-pressure reactive systems (T > 600 K, P < 100 bar) behind reflected shock waves. In this paper, wemore » present results of a PI-TOF-MS study at the Advanced Light Source at Lawrence Berkeley National Laboratory. Dimethyl ether pyrolysis (2% CH3OCH3/Ar) was observed behind the reflected shock (1400 < T-5 < 1700 K, 3 < P-5 < 16 bar) with ionization energies between 10 and 13 eV. Individual experiments have extremely low signal levels. However, product species and radical intermediates are well-resolved when averaging over hundreds of shots, which is ordinarily impractical in conventional shock tube studies. The signal levels attained and data throughput rates with this technique are comparable to those with other synchrotron-based PI-TOF-MS reactors, and it is anticipated that this high pressure technique will greatly complement those lower pressure techniques.« less

  15. Stanford Synchrotron Radiation Laboratory activity report for 1986

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cantwell, K.

    1987-12-31

    1986 was another year of major advances for SSRL as the ultimate capabilities of PEP as a synchrotron radiation source became more apparent and a second PEP beam line was initiated, while effective development and utilization of SPEAR proceeded. Given these various PEP developments, SSRL abandoned its plans for a separate diffraction limited ring, as they abandoned their plans for a 6--7 GeV ring of the APS type last year. It has become increasingly apparent that SSRL should concentrate on developing SPEAR and PEP as synchrotron radiation sources. Consequently, initial planning for a 3 GeV booster synchrotron injector for SPEARmore » was performed in 1986, with a proposal to the Department of Energy resulting. As described in Chapter 2, the New Rings Group and the Machine Physics Group were combined into one Accelerator Physics Group. This group is focusing mainly on the improvement of SPEAR`s operating conditions and on planning for the conversion of PEP into a fourth generation x-ray source. Considerable emphasis is also being given to the training of accelerator physics graduate students. At the same time, several improvements of SSRL`s existing facilities were made. These are described in Chapter 3. Chapter 4 describes new SSRL beam lines being commissioned. Chapter 5 discusses SSRL`s present construction projects. Chapter 6 discusses a number of projects presently underway in the engineering division. Chapter 7 describes SSRL`s advisory panels while Chapter 8 discusses SSRL`s overall organization. Chapter 9 describes the experimental progress reports.« less

  16. Galactic synchrotron radiation from radio to microwaves, and its relation to cosmic-ray propagation models: past, present and future

    NASA Astrophysics Data System (ADS)

    Orlando, Elena

    2016-04-01

    Galactic synchrotron radiation observed from radio to microwaves is produced by cosmic-ray (CR) electrons propagating in magnetic fields (B-fields). The low-frequency foreground component separated maps by WMAP and Planck depend on the assumed synchrotron spectrum. The synchrotron spectrum varies for different line of sights as a result of changes on the CR spectrum due to propagation effects and source distributions. Our present knowledge of the CR spectrum at different locations in the Galaxy is not sufficient to distinguish various possibilities in the modeling. As a consequence uncertainties on synchrotron emission models complicate the foreground component separation analysis with Planck and future microwave telescopes. Hence, any advancement in synchrotron modeling is important for separating the different foreground components.The first step towards a more comprehensive understanding of degeneracy and correlation among the synchrotron model parameters is outlined in our Strong et al. 2011 and Orlando et al. 2013 papers. In the latter the conclusion was that CR spectrum, propagation models, B-fields, and foreground component separation analysis need to be studied simultaneously in order to properly obtain and interpret the synchrotron foreground. Indeed for the officially released Planck maps, we use only the best spectral model from our above paper for the component separation analysis.Here we present a collections of our latest results on synchrotron, CRs and B-fields in the context of CR propagation, showing also our recent work on B-fields within the Planck Collaboration. We underline also the importance of using the constraints on CRs that we obtain from gamma ray observations. Methods and perspectives for further studies on the synchrotron foreground will be addressed.

  17. Synchrotron pair halo and echo emission from blazars in the cosmic web: application to extreme TeV blazars

    NASA Astrophysics Data System (ADS)

    Oikonomou, Foteini; Murase, Kohta; Kotera, Kumiko

    2014-08-01

    High frequency peaked, high redshift blazars, are extreme in the sense that their spectrum is particularly hard and peaks at TeV energies. Standard leptonic scenarios require peculiar source parameters and/or a special setup in order to account for these observations. Electromagnetic cascades seeded by ultra-high energy cosmic rays (UHECR) in the intergalactic medium have also been invoked, assuming a very low intergalactic magnetic field (IGMF). Here we study the synchrotron emission of UHECR secondaries produced in blazars located in magnetised environments, and show that it can provide an alternative explanation to these challenged channels, for sources embedded in structured regions with magnetic field strengths of the order of 10-7 G. To demonstrate this, we focus on three extreme blazars: 1ES 0229+200, RGB J0710+591, and 1ES 1218+304. We model the expected gamma-ray signal from these sources through a combination of numerical Monte Carlo simulations and solving the kinetic equations of the particles in our simulations, and explore the UHECR source and intergalactic medium parameter space to test the robustness of the emission. We show that the generated synchrotron-pair halo and echo flux at the peak energy is not sensitive to variations in the overall IGMF strength. This signal is unavoidable in contrast to the inverse Compton-pair halo and echo intensity, which is appealing in view of the large uncertainties on the IGMF in voids of large scale structure. It is also shown that the variability of blazar gamma-ray emission can be accommodated by the synchrotron emission of secondary products of UHE neutral beams if these are emitted by UHECR accelerators inside magnetised regions.

  18. Coherent synchrotron radiation for laminar flows

    NASA Astrophysics Data System (ADS)

    Schmekel, Bjoern S.; Lovelace, Richard V. E.

    2006-11-01

    We investigate the effect of shear in the flow of charged particle equilibria that are unstable to the coherent synchrotron radiation (CSR) instability. Shear may act to quench this instability because it acts to limit the size of the region with a fixed phase relation between emitters. The results are important for the understanding of astrophysical sources of coherent radiation where shear in the flow is likely.

  19. Contrast agent choice for intravenous coronary angiography

    NASA Astrophysics Data System (ADS)

    Zeman, H. D.; Siddons, D. P.

    1990-05-01

    The screening of the general population for coronary artery disease would be practical if a method existed for visualizing the extent of occlusion after an intravenous injection of contrast agent. Measurements performed with monochromatic synchrotron radiation X-rays and an iodine-containing contrast agent at the Stanford Synchrotron Radiation Laboratory have shown that such an intravenous angiography procedure would be possible with an adequately intense monochromatic X-ray source. Because of the size and cost of synchrotron radiation facilities it would be desirable to make the most efficient use of the intensity available, while reducing as much as possible the radiation dose experienced by the patient. By choosing contrast agents containing elements with a higher atomic number than iodine, it is possible to both improve the image quality and reduce the patient radiation dose, while using the same synchrotron radiation source. By using Si monochromator crystals with a small mosaic spread, it is possible to increase the X-ray flux available for imaging by over an order of magnitude, without any changes in the storage ring or wiggler magnet. The most critical imaging task for intravenous coronary angiography utilizing synchrotron radiation X-rays is visualizing a coronary artery through the left ventricle or aorta which also contain contrast agent. Calculations have been made of the signal to noise ratio expected for this imaging task for various contrast agents with atomic numbers between that of iodine and bismuth. The X-ray energy spectrum of the X-17 superconduction wiggler beam line at the National Synchrotron Light Source at Brookhaven National Laboratory has been used for these calculations. Both perfect Si crystals and Si crystals with a small mosaic spread are considered as monochromators. Contrast agents containing Gd or Yb seem to have about the optimal calculated signal to noise ratio. Gd-DTPA is already approved for use as a contrast agent for magnetic resonance imaging. Experiments have already been performed with Yb-DTPA in animals, and it appears to have a lower toxicity than that of Gd-DTPA. Reported animal experiments with Gd-DOTA contrast agent show no toxicity at all.

  20. New theoretical results in synchrotron radiation

    NASA Astrophysics Data System (ADS)

    Bagrov, V. G.; Gitman, D. M.; Tlyachev, V. B.; Jarovoi, A. T.

    2005-11-01

    One of the remarkable features of the relativistic electron synchrotron radiation is its concentration in small angle Δ ≈ 1/γ (here γ-relativistic factor: γ = E/mc2, E energy, m electron rest mass, c light velocity) near rotation orbit plane [V.G. Bagrov, V.A. Bordovitsyn, V.G. Bulenok, V. Ya. Epp, Kinematical projection of pulsar synchrotron radiation profiles, in: Proceedings of IV ISTC Scientific Advisory Commitee Seminar on Basic Science in ISTC Aktivities, Akademgorodok, Novosibirsk, April 23 27, 2001, p. 293 300]. This theoretically predicted and experimentally confirmed feature is peculiar to total (spectrum summarized) radiating intensity. This angular distribution property has been supposed to be (at least qualitatively) conserved and for separate spectrum synchrotron radiation components. In the work of V.G. Bagrov, V.A. Bordovitsyn, V. Ch. Zhukovskii, Development of the theory of synchrotron radiation and related processes. Synchrotron source of JINR: the perspective of research, in: The Materials of the Second International Work Conference, Dubna, April 2 6, 2001, pp. 15 30 and in Angular dependence of synchrotron radiation intensity. http://lanl.arXiv.org/abs/physics/0209097, it is shown that the angular distribution of separate synchrotron radiation spectrum components demonstrates directly inverse tendency the angular distribution deconcentration relatively the orbit plane takes place with electron energy growth. The present work is devoted to detailed investigation of this situation. For exact quantitative estimation of angular concentration degree of synchrotron radiation the definition of radiation effective angle and deviation angle is proposed. For different polarization components of radiation the dependence of introduced characteristics was investigated as a functions of electron energy and number of spectrum component.

  1. Characterizing radio continuum sources in a sample of Hi-GAL massive cores

    NASA Astrophysics Data System (ADS)

    Armstrong, Jason

    In 2012 and 2013, Olmi and collaborators conducted a survey for 6.7GHz methanol masers with the Arecibo Telescope toward far infrared sources selected from the Hi-GAL catalog of massive cores. They reported a number of sources with weak 6.7GHz methanol masers, possibly indicating regions in early stages of star formation. Follow-up observations were conducted with the Karl G. Jansky Very Large Array (VLA) in New Mexico to characterize the sources. This thesis presents the results of radio continuum observations of nine of the Arecibo regions. A total of 33 radio continuum sources were detected. The nature of the radio continuum sources was analyzed based on their spectral indices. Most of the sources have negative spectral indices, which is indicative of synchrotron radiation. Many of the synchrotron sources are associated with a supernova remnant in our Galaxy, while the rest are likely background radio galaxies and quasars. Evidence for thermal bremsstrahlung radiation was found toward six sources associated with the Arecibo regions, which is consistent with the interpretation of gas ionized by young high-mass stellar objects.

  2. Synchrotron FTIR Imaging For The Identification Of Cell Types Within Human Tissues

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Walsh, Michael J.; Pounder, F. Nell; Nasse, Michael J.

    2010-02-03

    The use of synchrotron Fourier Transform Infrared spectroscopy (S-FTIR) has been shown to be a very promising tool for biomedical research. S-FTIR spectroscopy allows for the fast acquisition of infrared (IR) spectra at a spatial resolution approaching the IR diffraction limit. The development of the Infrared Environmental Imaging (IRENI) beamline at the Synchrotron Radiation Center (SRC) at the University of Wisconsin-Madison has allowed for diffraction limited imaging measurements of cells in human prostate and breast tissues. This has allowed for the identification of cell types within tissues that would otherwise not have been resolvable using conventional FTIR sources.

  3. Observation of superradiant synchrotron radiation in the terahertz region

    NASA Astrophysics Data System (ADS)

    Billinghurst, B. E.; Bergstrom, J. C.; Dallin, L.; de Jong, M.; May, T. E.; Vogt, J. M.; Wurtz, W. A.

    2013-06-01

    We report the first high-resolution measurement of superradiance, using coherent synchrotron radiation in the terahertz region from the Canadian Light Source synchrotron and a Michelson interferometer with a nominal frequency resolution of 0.00096cm-1. Superradiance arises when a high degree of phase coherence exists between the radiation fields of the individual electron bunches, and manifests itself as a series of narrow spectral peaks at harmonics of the bunch frequency. We observe an enhancement factor of 16 at the spectral peaks, limited by the interferometer resolution. The spectral distribution and relative amplitudes of the superradiant peaks are modified by altering the pattern of bunches along the bunch train.

  4. Puzzles, Pastimes, Problems.

    ERIC Educational Resources Information Center

    Eperson, D. B.

    1985-01-01

    Presents six mathematical problems (with answers) which focus on: (1) chess moves; (2) patterned numbers; (3) quadratics with rational roots; (4) number puzzles; (5) Euclidean geometry; and (6) Carrollian word puzzles. (JN)

  5. Automatic Camera Calibration for Cultural Heritage Applications Using Unstructured Planar Objects

    NASA Astrophysics Data System (ADS)

    Adam, K.; Kalisperakis, I.; Grammatikopoulos, L.; Karras, G.; Petsa, E.

    2013-07-01

    As a rule, image-based documentation of cultural heritage relies today on ordinary digital cameras and commercial software. As such projects often involve researchers not familiar with photogrammetry, the question of camera calibration is important. Freely available open-source user-friendly software for automatic camera calibration, often based on simple 2D chess-board patterns, are an answer to the demand for simplicity and automation. However, such tools cannot respond to all requirements met in cultural heritage conservation regarding possible imaging distances and focal lengths. Here we investigate the practical possibility of camera calibration from unknown planar objects, i.e. any planar surface with adequate texture; we have focused on the example of urban walls covered with graffiti. Images are connected pair-wise with inter-image homographies, which are estimated automatically through a RANSAC-based approach after extracting and matching interest points with the SIFT operator. All valid points are identified on all images on which they appear. Provided that the image set includes a "fronto-parallel" view, inter-image homographies with this image are regarded as emulations of image-to-world homographies and allow computing initial estimates for the interior and exterior orientation elements. Following this initialization step, the estimates are introduced into a final self-calibrating bundle adjustment. Measures are taken to discard unsuitable images and verify object planarity. Results from practical experimentation indicate that this method may produce satisfactory results. The authors intend to incorporate the described approach into their freely available user-friendly software tool, which relies on chess-boards, to assist non-experts in their projects with image-based approaches.

  6. Towards a table-top synchrotron based on supercontinuum generation

    NASA Astrophysics Data System (ADS)

    Petersen, Christian R.; Moselund, Peter M.; Huot, Laurent; Hooper, Lucy; Bang, Ole

    2018-06-01

    Recently, high brightness and broadband supercontinuum (SC) sources reaching far into the infrared (IR) have emerged with the potential to rival traditional broadband sources of IR radiation. Here, the brightness of these IR SC sources is compared with that of synchrotron IR beamlines and SiC thermal emitters (Globars). It is found that SC sources can deliver a brightness that is 5-6 orders of magnitude higher than Globars and 1-2 orders of magnitude higher than typical IR beamlines, matching the beamlines at least out to 10.6 μm (940 cm-1). This means that these sources can now cover nearly all of the 800-5000 cm-1 spectrum (2-12.5 μm) which is frequently used in IR spectroscopy and microscopy. To demonstrate applicability, such an IR SC source was used for transmission spectroscopy of highly scattering filtration membranes from 3500 to 1300 cm-1, and transmission microscopy of colon tissue at 1538 cm-1.

  7. 7 CFR 201.60 - Purity percentages.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...- squirreltail, bromes, buffalograss, buffelgrass, carpetgrass, soft chess, dallisgrass, fescues, foxtails... computing tolerances for nonchaffy kinds the values for T1 are taken from column C of Table 3, and for...

  8. Expertise and processing distorted structure in chess.

    PubMed

    Bartlett, James C; Boggan, Amy L; Krawczyk, Daniel C

    2013-01-01

    A classic finding in research on human expertise and knowledge is that of enhanced memory for stimuli in a domain of expertise as compared to either stimuli outside that domain, or within-domain stimuli that have been degraded or distorted in some way. However, we do not understand how experts process degradation or distortion of stimuli within the expert domain (e.g., a face with the eyes, nose, and mouth in the wrong positions, or a chessboard with pieces placed randomly). Focusing on the domain of chess, we present new fMRI evidence that when experts view such distorted/within-domain stimuli, they engage an active search for structure-a kind of exploratory chunking-that involves a component of a prefrontal-parietal network linked to consciousness, attention and working memory.

  9. Expertise and processing distorted structure in chess

    PubMed Central

    Bartlett, James C.; Boggan, Amy L.; Krawczyk, Daniel C.

    2013-01-01

    A classic finding in research on human expertise and knowledge is that of enhanced memory for stimuli in a domain of expertise as compared to either stimuli outside that domain, or within-domain stimuli that have been degraded or distorted in some way. However, we do not understand how experts process degradation or distortion of stimuli within the expert domain (e.g., a face with the eyes, nose, and mouth in the wrong positions, or a chessboard with pieces placed randomly). Focusing on the domain of chess, we present new fMRI evidence that when experts view such distorted/within-domain stimuli, they engage an active search for structure—a kind of exploratory chunking—that involves a component of a prefrontal-parietal network linked to consciousness, attention and working memory. PMID:24348371

  10. Molecular computation: RNA solutions to chess problems

    PubMed Central

    Faulhammer, Dirk; Cukras, Anthony R.; Lipton, Richard J.; Landweber, Laura F.

    2000-01-01

    We have expanded the field of “DNA computers” to RNA and present a general approach for the solution of satisfiability problems. As an example, we consider a variant of the “Knight problem,” which asks generally what configurations of knights can one place on an n × n chess board such that no knight is attacking any other knight on the board. Using specific ribonuclease digestion to manipulate strands of a 10-bit binary RNA library, we developed a molecular algorithm and applied it to a 3 × 3 chessboard as a 9-bit instance of this problem. Here, the nine spaces on the board correspond to nine “bits” or placeholders in a combinatorial RNA library. We recovered a set of “winning” molecules that describe solutions to this problem. PMID:10677471

  11. Magnetic fields in Supernova Remnants and Pulsar-Wind Nebulae: Deductions from X-ray Observations

    NASA Astrophysics Data System (ADS)

    Reynolds, S. P.

    2016-06-01

    Magnetic field strengths B in synchrotron sources are notoriously difficult to measure. Simple arguments such as equipartition of energy can give values for which the total energy is a minimum, but there is no guarantee that Nature obeys it, or even if so, what particle population (just electrons? electrons plus ions?) should have an energy density comparable to that in magnetic field. However, the operation of synchrotron losses can provide additional information, if those losses are manifested in the synchrotron spectra as steepenings of the spectral-energy distribution above some characteristic frequency often called a "break" (though it is more typically a gradual curvature). A source of known age, if it has been accelerating particles continuously, will have such a break above the energy at which particle radiative lifetimes equal the source age, and this can give B. However, in spatially resolved sources such as supernova remnants (SNRs) and pulsar-wind nebulae (PWNe), systematic advection of particles, if at a known rate, gives a second measure of particle age to compare with radiative lifetimes. In most young SNRs, synchrotron X-rays make a contribution to the X-ray spectrum, and are usually found in thin rims at the remnant edges. If the rims are thin in the radial direction due to electron energy losses, a magnetic-field strength can be estimated. I present recent modeling of this process, along with models in which rims are thin due to decay of magnetic turbulence, and apply them to the remnants of SN 1006 and Tycho. In PWNe, outflows of relativistic plasma behind the pulsar wind termination shock are likely quite inhomogeneous, so magnetic-field estimates based on source lifetimes and assuming spatial uniformity can give misleading values for B. I shall discuss inhomogeneous PWN models and the effects they can have on B estimates.

  12. A compact 500 MHz 4 kW Solid-State Power Amplifier for accelerator applications

    NASA Astrophysics Data System (ADS)

    Gaspar, M.; Pedrozzi, M.; Ferreira, L. F. R.; Garvey, T.

    2011-05-01

    We present the development of a compact narrow-band Solid-State Power Amplifier (SSPA). We foresee a promising application of solid-state amplifiers specifically in accelerators for new generation synchrotron light sources. Such a new technology has reached a competitive price/performance ratio and expected lifetime in comparison with klystron and IOT amplifiers. The increasing number of synchrotron light sources using 500 MHz as base frequency justifies the effort in the development of the proposed amplifier. Two different techniques are also proposed to improve the control and performance of these new distributed amplification systems which we call, respectively, complete distributed system and forced compression.

  13. Sirepo for Synchrotron Radiation Workshop

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nagler, Robert; Moeller, Paul; Rakitin, Maksim

    Sirepo is an open source framework for cloud computing. The graphical user interface (GUI) for Sirepo, also known as the client, executes in any HTML5 compliant web browser on any computing platform, including tablets. The client is built in JavaScript, making use of the following open source libraries: Bootstrap, which is fundamental for cross-platform web applications; AngularJS, which provides a model–view–controller (MVC) architecture and GUI components; and D3.js, which provides interactive plots and data-driven transformations. The Sirepo server is built on the following Python technologies: Flask, which is a lightweight framework for web development; Jinja, which is a secure andmore » widely used templating language; and Werkzeug, a utility library that is compliant with the WSGI standard. We use Nginx as the HTTP server and proxy, which provides a scalable event-driven architecture. The physics codes supported by Sirepo execute inside a Docker container. One of the codes supported by Sirepo is the Synchrotron Radiation Workshop (SRW). SRW computes synchrotron radiation from relativistic electrons in arbitrary magnetic fields and propagates the radiation wavefronts through optical beamlines. SRW is open source and is primarily supported by Dr. Oleg Chubar of NSLS-II at Brookhaven National Laboratory.« less

  14. Real Time In Situ Observations of Equiaxed Dendrite Coherency in Al-Cu Alloys Using High-Brilliance, 3rd Generation Synchrotron Sources

    NASA Technical Reports Server (NTRS)

    Murphy, Andrew G.; Browne, David J.; Mirihanage, Wajira U.; Mathiesen, Ragnvald H.

    2012-01-01

    In the last decade synchrotron X-ray sources have fast become the tool of choice for performing in-situ high resolution imaging during alloy solidification. This paper presents the results of an experimental campaign carried out at the European Synchrotron Radiation Facility, using a Bridgman furnace, to monitor phenomena during solidification of Al-Cu alloys - specifically the onset of equiaxed dendrite coherency. Conventional experimental methods for determining coherency involve measuring the change in viscosity or measuring the change in thermal conductivity across the solidifying melt Conflicts arise when comparing the results of these experimental techniques to find a relationship between cooling rate and coherency fraction. It has been shown that the ratio of average velocity to the average grain diameter has an inversely proportional relationship to coherency fraction. In-situ observation therefore makes it possible to measure these values directly from acquired images sequences and make comparisons with published results.

  15. Observing microscopic structures of a relativistic object using a time-stretch strategy.

    PubMed

    Roussel, E; Evain, C; Le Parquier, M; Szwaj, C; Bielawski, S; Manceron, L; Brubach, J-B; Tordeux, M-A; Ricaud, J-P; Cassinari, L; Labat, M; Couprie, M-E; Roy, P

    2015-05-28

    Emission of light by a single electron moving on a curved trajectory (synchrotron radiation) is one of the most well-known fundamental radiation phenomena. However experimental situations are more complex as they involve many electrons, each being exposed to the radiation of its neighbors. This interaction has dramatic consequences, one of the most spectacular being the spontaneous formation of spatial structures inside electrons bunches. This fundamental effect is actively studied as it represents one of the most fundamental limitations in electron accelerators, and at the same time a source of intense terahertz radiation (Coherent Synchrotron Radiation, or CSR). Here we demonstrate the possibility to directly observe the electron bunch microstructures with subpicosecond resolution, in a storage ring accelerator. The principle is to monitor the terahertz pulses emitted by the structures, using a strategy from photonics, time-stretch, consisting in slowing-down the phenomena before recording. This opens the way to unpreceeded possibilities for analyzing and mastering new generation high power coherent synchrotron sources.

  16. Observing microscopic structures of a relativistic object using a time-stretch strategy

    NASA Astrophysics Data System (ADS)

    Roussel, E.; Evain, C.; Le Parquier, M.; Szwaj, C.; Bielawski, S.; Manceron, L.; Brubach, J.-B.; Tordeux, M.-A.; Ricaud, J.-P.; Cassinari, L.; Labat, M.; Couprie, M.-E.; Roy, P.

    2015-05-01

    Emission of light by a single electron moving on a curved trajectory (synchrotron radiation) is one of the most well-known fundamental radiation phenomena. However experimental situations are more complex as they involve many electrons, each being exposed to the radiation of its neighbors. This interaction has dramatic consequences, one of the most spectacular being the spontaneous formation of spatial structures inside electrons bunches. This fundamental effect is actively studied as it represents one of the most fundamental limitations in electron accelerators, and at the same time a source of intense terahertz radiation (Coherent Synchrotron Radiation, or CSR). Here we demonstrate the possibility to directly observe the electron bunch microstructures with subpicosecond resolution, in a storage ring accelerator. The principle is to monitor the terahertz pulses emitted by the structures, using a strategy from photonics, time-stretch, consisting in slowing-down the phenomena before recording. This opens the way to unpreceeded possibilities for analyzing and mastering new generation high power coherent synchrotron sources.

  17. Brookhaven highlights. Report on research, October 1, 1992--September 30, 1993

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rowe, M.S.; Belford, M.; Cohen, A.

    This report highlights the research activities of Brookhaven National Laboratory during the period dating from October 1, 1992 through September 30, 1993. There are contributions to the report from different programs and departments within the laboratory. These include technology transfer, RHIC, Alternating Gradient Synchrotron, physics, biology, national synchrotron light source, applied science, medical science, advanced technology, chemistry, reactor physics, safety and environmental protection, instrumentation, and computing and communications.

  18. Brookhaven National Laboratory technology transfer report, fiscal year 1987

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1987-01-01

    The Brookhaven Office of Research and Technology Applications (ORTA) inaugurated two major initiatives. The effort by our ORTA in collaboration with the National Synchrotron Light Source (NSLS) has succeeded in alerting American industry to the potential of using a synchrotron x-ray source for high resolution lithography. We are undertaking a preconstruction study for the construction of a prototype commercial synchrotron and development of an advanced commercial cryogenic synchrotron (XLS). ORTA sponsored a technology transfer workshop where industry expressed its views on how to transfer accelerator technology during the construction of the prototype commercial machine. The Northeast Regional utility Initiative broughtmore » 14 utilities to a workshop at the Laboratory in November. One recommendation of this workshop was to create a Center at the Laboratory for research support on issues of interest to utilities in the region where BNL has unique capability. The ORTA has initiated discussions with the New York State Science and Technology Commission, Cornell University's world renowned Nannofabrication Center and the computer aided design capabilities at SUNY at Stony Brook to create, centered around the NSLS and the XLS, the leading edge semiconductor process technology development center when the XLS becomes operational in two and a half years. 1 fig.« less

  19. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hettiarachchi, Ganga M.; Donner, Erica; Doelsch, Emmanuel

    To understand the biogeochemistry of nutrients and contaminants in environmental media, their speciation and behavior under different conditions and at multiple scales must be determined. Synchrotron radiation-based X-ray techniques allow scientists to elucidate the underlying mechanisms responsible for nutrient and contaminant mobility, bioavailability, and behavior. The continuous improvement of synchrotron light sources and X-ray beamlines around the world has led to a profound transformation in the field of environmental biogeochemistry and, subsequently, to significant scientific breakthroughs. Following this introductory paper, this special collection includes 10 papers that either present targeted reviews of recent advancements in spectroscopic methods that are applicablemore » to environmental biogeochemistry or describe original research studies conducted on complex environmental samples that have been significantly enhanced by incorporating synchrotron radiation-based X-ray technique(s). We believe that the current focus on improving the speciation of ultra-dilute elements in environmental media through the ongoing optimization of synchrotron technologies (e.g., brighter light sources, improved monochromators, more efficient detectors) will help to significantly push back the frontiers of environmental biogeochemistry research. As many of the relevant techniques produce extremely large datasets, we also identify ongoing improvements in data processing and analysis (e.g., software improvements and harmonization of analytical methods) as a significant requirement for environmental biogeochemists to maximize the information that can be gained using these powerful tools.« less

  20. Training Ideas Found Useful

    ERIC Educational Resources Information Center

    Suessmuth, Patrick; Stengels, Marit

    1970-01-01

    Group decision on the moving of chess pawns is a useful way to demonstrate to students in a management development situation how ineffectively they use the resources available in a work situation. (MF)

  1. Invited Article: Refined analysis of synchrotron radiation for NIST's SURF III facility

    NASA Astrophysics Data System (ADS)

    Shirley, Eric L.; Furst, Mitchell; Arp, Uwe

    2018-04-01

    We have developed a new method for the exact calculation of synchrotron radiation for the National Institute of Standards and Technology Synchrotron Ultraviolet Radiation Facility, SURF III. Instead of using the Schwinger formula, which is only an approximation, we develop formulae based on Graf's addition theorem for Bessel functions and accurate asymptotic expansions for Hankel functions and Bessel functions. By measuring the radiation intensity profile at two distances from the storage ring, we also confirm an apparent vertical emittance that is consistent with the vertical betatron oscillations that are intentionally introduced to extend beam lifetime by spreading the electron beam spatially. Finally, we determine how much diffraction by beamline apertures enhances the spectral irradiance at an integrating sphere entrance port at the end station. This should eliminate small but treatable components of the uncertainty budget that one should consider when using SURF III or similar synchrotrons as standard, calculable sources of ultraviolet and other radiation.

  2. The cost of severe haemophilia in Europe: the CHESS study.

    PubMed

    O'Hara, Jamie; Hughes, David; Camp, Charlotte; Burke, Tom; Carroll, Liz; Diego, Daniel-Anibal Garcia

    2017-05-31

    Severe haemophilia is associated with major psychological and economic burden for patients, caregivers, and the wider health care system. This burden has been quantified and documented for a number of European countries in recent years. However, few studies have taken a standardised methodology across multiple countries simultaneously, and sought to amalgamate all three levels of burden for severe disease. The overall aim of the 'Cost of Haemophilia in Europe: a Socioeconomic Survey' (CHESS) study was to capture the annualised economic and psychosocial burden of severe haemophilia in five European countries. A cross-section of haemophilia specialists (surveyed between January and April 2015) provided demographic and clinical information and 12-month ambulatory and secondary care activity for patients via an online survey. In turn, patients provided corresponding direct and indirect non-medical cost information, including work loss and out-of-pocket expenses, as well as information on quality of life and adherence. The direct and indirect costs for the patient sample were calculated and extrapolated to population level. Clinical reports for a total of 1,285 patients were received. Five hundred and fifty-two patients (43% of the sample) provided information on indirect costs and health-related quality of life via the PSC. The total annual cost of severe haemophilia across the five countries for 2014 was estimated at EUR 1.4 billion, or just under EUR 200,000 per patient. The highest per-patient costs were in Germany (mean EUR 319,024) and the lowest were in the United Kingdom (mean EUR 129,365), with a study average of EUR 199,541. As expected, consumption of clotting factor replacement therapy represented the vast majority of costs (up to 99%). Indirect costs are driven by patient and caregiver work loss. The results of the CHESS study reflect previous research findings suggesting that costs of factor replacement therapy account for the vast majority of the cost burden in severe haemophilia. However, the importance of the indirect impact of haemophilia on the patient and family should not be overlooked. The CHESS study highlights the benefits of observational study methodologies in capturing a 'snapshot' of information for patients with rare diseases.

  3. Electron beam ion sources for use in second generation synchrotrons for medical particle therapy

    NASA Astrophysics Data System (ADS)

    Zschornack, G.; Ritter, E.; Schmidt, M.; Schwan, A.

    2014-02-01

    Cyclotrons and first generation synchrotrons are the commonly applied accelerators in medical particle therapy nowadays. Next generation accelerators such as Rapid Cycling Medical Synchrotrons (RCMS), direct drive accelerators, or dielectric wall accelerators have the potential to improve the existing accelerator techniques in this field. Innovative accelerator concepts for medical particle therapy can benefit from ion sources which meet their special requirements. In the present paper we report on measurements with a superconducting Electron Beam Ion Source, the Dresden EBIS-SC, under the aspect of application in combination with RCMS as a well proven technology. The measurements indicate that this ion source can offer significant advantages for medical particle therapy. We show that a superconducting EBIS can deliver ion pulses of medically relevant ions such as protons, C4 + and C6 + ions with intensities and frequencies required for RCMS [S. Peggs and T. Satogata, "A survey of Hadron therapy accelerator technology," in Proceedings of PAC07, BNL-79826- 2008-CP, Albuquerque, New Mexico, USA, 2007; A. Garonna, U. Amaldi et al., "Cyclinac medical accelerators using pulsed C6 +/H+_2 ion sources," in Proceedings of EBIST 2010, Stockholm, Sweden, July 2010]. Ion extraction spectra as well as individual ion pulses have been measured. For example, we report on the generation of proton pulses with up to 3 × 109 protons per pulse and with frequencies of up to 1000 Hz at electron beam currents of 600 mA.

  4. Operation of the Australian Store.Synchrotron for macromolecular crystallography

    PubMed Central

    Meyer, Grischa R.; Aragão, David; Mudie, Nathan J.; Caradoc-Davies, Tom T.; McGowan, Sheena; Bertling, Philip J.; Groenewegen, David; Quenette, Stevan M.; Bond, Charles S.; Buckle, Ashley M.; Androulakis, Steve

    2014-01-01

    The Store.Synchrotron service, a fully functional, cloud computing-based solution to raw X-ray data archiving and dissemination at the Australian Synchrotron, is described. The service automatically receives and archives raw diffraction data, related metadata and preliminary results of automated data-processing workflows. Data are able to be shared with collaborators and opened to the public. In the nine months since its deployment in August 2013, the service has handled over 22.4 TB of raw data (∼1.7 million diffraction images). Several real examples from the Australian crystallographic community are described that illustrate the advantages of the approach, which include real-time online data access and fully redundant, secure storage. Discoveries in biological sciences increasingly require multidisciplinary approaches. With this in mind, Store.Synchrotron has been developed as a component within a greater service that can combine data from other instruments at the Australian Synchrotron, as well as instruments at the Australian neutron source ANSTO. It is therefore envisaged that this will serve as a model implementation of raw data archiving and dissemination within the structural biology research community. PMID:25286837

  5. Operation of the Australian Store.Synchrotron for macromolecular crystallography.

    PubMed

    Meyer, Grischa R; Aragão, David; Mudie, Nathan J; Caradoc-Davies, Tom T; McGowan, Sheena; Bertling, Philip J; Groenewegen, David; Quenette, Stevan M; Bond, Charles S; Buckle, Ashley M; Androulakis, Steve

    2014-10-01

    The Store.Synchrotron service, a fully functional, cloud computing-based solution to raw X-ray data archiving and dissemination at the Australian Synchrotron, is described. The service automatically receives and archives raw diffraction data, related metadata and preliminary results of automated data-processing workflows. Data are able to be shared with collaborators and opened to the public. In the nine months since its deployment in August 2013, the service has handled over 22.4 TB of raw data (∼1.7 million diffraction images). Several real examples from the Australian crystallographic community are described that illustrate the advantages of the approach, which include real-time online data access and fully redundant, secure storage. Discoveries in biological sciences increasingly require multidisciplinary approaches. With this in mind, Store.Synchrotron has been developed as a component within a greater service that can combine data from other instruments at the Australian Synchrotron, as well as instruments at the Australian neutron source ANSTO. It is therefore envisaged that this will serve as a model implementation of raw data archiving and dissemination within the structural biology research community.

  6. A compact tunable polarized X-ray source based on laser-plasma helical undulators

    PubMed Central

    Luo, J.; Chen, M.; Zeng, M.; Vieira, J.; Yu, L. L.; Weng, S. M.; Silva, L. O.; Jaroszynski, D. A.; Sheng, Z. M.; Zhang, J.

    2016-01-01

    Laser wakefield accelerators have great potential as the basis for next generation compact radiation sources because of their extremely high accelerating gradients. However, X-ray radiation from such devices still lacks tunability, especially of the intensity and polarization distributions. Here we propose a tunable polarized radiation source based on a helical plasma undulator in a plasma channel guided wakefield accelerator. When a laser pulse is initially incident with a skew angle relative to the channel axis, the laser and accelerated electrons experience collective spiral motions, which leads to elliptically polarized synchrotron-like radiation with flexible tunability on radiation intensity, spectra and polarization. We demonstrate that a radiation source with millimeter size and peak brilliance of 2 × 1019 photons/s/mm2/mrad2/0.1% bandwidth can be made with moderate laser and electron beam parameters. This brilliance is comparable with third generation synchrotron radiation facilities running at similar photon energies, suggesting that laser plasma based radiation sources are promising for advanced applications. PMID:27377126

  7. Giant Metrewave Radio Telescope Observations of Head–Tail Radio Galaxies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sebastian, Biny; Lal, Dharam V.; Rao, A. Pramesh, E-mail: biny@ncra.tifr.res.in

    We present results from a study of seven large known head–tail radio galaxies based on observations using the Giant Metrewave Radio Telescope at 240 and 610 MHz. These observations are used to study the radio morphologies and distribution of the spectral indices across the sources. The overall morphology of the radio tails of these sources is suggestive of random motions of the optical host around the cluster potential. The presence of multiple bends and wiggles in several head–tail sources is possibly due to the precessing radio jets. We find steepening of the spectral index along the radio tails. The prevailingmore » equipartition magnetic field also decreases along the radio tails of these sources. These steepening trends are attributed to the synchrotron aging of plasma toward the ends of the tails. The dynamical ages of these sample sources have been estimated to be ∼10{sup 8} yr, which is a factor of six more than the age estimates from the radiative losses due to synchrotron cooling.« less

  8. 6. LOWER TERRACE, LOOKING WEST FROM BUCHANAN MEMORIAL, NOTE HUMANSCALE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. LOWER TERRACE, LOOKING WEST FROM BUCHANAN MEMORIAL, NOTE HUMAN-SCALE CHESS BOARD, August 1976 - Meridian Hill Park, Bounded by Fifteenth, Sixteenth, Euclid & W Streets, Northwest, Washington, District of Columbia, DC

  9. Overextension in verb conjunctions.

    PubMed

    Jönsson, Martin L

    2015-11-01

    Hampton (1988) discovered that people are subject to overextension-they categorize some things as falling under a conjunction (e.g., they categorize chess as a sport which is also a game) but not as falling under both of the corresponding conjuncts (e.g., they do not categorize chess as a sport). Although subsequent literature has replicated this effect with a wider range of constructions than those originally used by Hampton, the research so far has been exclusively concerned with various forms of noun compounds. This article generalizes the previous findings to the domain of verb conjunctions. By using a novel paradigm for studying overextension effects, this study demonstrates a very strong overextension effect for conjunctions of gerunds (e.g., walking and smoking). The author discusses the implications of the new findings for available explanations of overextension. (c) 2015 APA, all rights reserved).

  10. Motivational interviewing combined with chess accelerates improvement in executive functions in cocaine dependent patients: a one-month prospective study.

    PubMed

    Gonçalves, Priscila Dib; Ometto, Mariella; Bechara, Antoine; Malbergier, André; Amaral, Ricardo; Nicastri, Sergio; Martins, Paula A; Beraldo, Livia; dos Santos, Bernardo; Fuentes, Daniel; Andrade, Arthur G; Busatto, Geraldo F; Cunha, Paulo Jannuzzi

    2014-08-01

    In cocaine-dependent individuals, executive function (EF) deficits are associated with poor treatment outcomes. Psychological interventions and pharmacological approaches have produced only modest effect sizes. To date, studies of this topic have been few and limited. The aim of this study was to examine the effects of a new model of intervention, which integrates chess and Motivational Interviewing, Motivational Chess (MC) METHODS: We evaluated 46 cocaine-dependent inpatients (aged 18-45), in two groups-MC (n=26); and active comparison-AC (n=20). Using neuropsychological tests and an impulsivity scale, we assessed the subjects before and after the study period (one month of abstinence monitored by urine toxicology screening). The MC and AC groups did not differ at baseline. In the post-intervention assessment (after one month), both groups showed significant improvements in attention, mental flexibility, inhibitory control, abstraction abilities, and decision-making (p<0.01). In addition, the improvement in working memory was more significant in the MC group than in the AC group (group-by-time interaction, p=01). One month of abstinence was sufficient to improve various attentional and executive domains in cocaine-dependent subjects. The MC intervention was associated with greater improvements in EFs, especially working memory, suggesting that tailored interventions focusing on complex EFs accelerate the process of cognitive recovery during the initial period of abstinence. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  11. Lingering fat signals with CHESS in simultaneous imaging of both hands can be improved with rice pads in both 1.5T and 3.0T.

    PubMed

    Moriya, Susumu; Miki, Yukio; Kamishima, Tamotsu; Miyati, Tosiaki; Kanagaki, Mitsunori; Matsuno, Yukako; Yokobayashi, Tsuneo

    2013-09-01

    To investigate whether rice pads can eliminate lingering fat signals of the complex surface shape of both hands that occur with chemical shift selective (CHESS) at 1.5T and 3.0T. T1-weighted images were obtained with CHESS using 1.5T and 3.0T systems. The same imaging parameters were used with and without rice pads on the coronal plane of both hands in 10 healthy volunteers. The fat-suppression effects were classified into four categories and scored for images, and visual evaluations were performed by one radiologist and one radiologic technologist. At 1.5T, the mean evaluation score was 1.55 for images obtained without rice pads and 3.50 for images obtained with rice pads. At 3.0T, the mean evaluation score was 1.10 for images obtained without rice pads and 3.20 for images obtained with rice pads. With both systems, images obtained with the rice pads showed significantly better fat suppression effects than images obtained without rice pads (P<0.0001, P<0.0001). It was confirmed that lingering fat signals are eliminated and good fat-suppressed images are obtained with the use of rice pads at 1.5T and 3.0T. Rice pads are therefore useful with at 1.5T and 3.0T, which are currently becoming more widely used. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  12. Playing off the curve - testing quantitative predictions of skill acquisition theories in development of chess performance.

    PubMed

    Gaschler, Robert; Progscha, Johanna; Smallbone, Kieran; Ram, Nilam; Bilalić, Merim

    2014-01-01

    Learning curves have been proposed as an adequate description of learning processes, no matter whether the processes manifest within minutes or across years. Different mechanisms underlying skill acquisition can lead to differences in the shape of learning curves. In the current study, we analyze the tournament performance data of 1383 chess players who begin competing at young age and play tournaments for at least 10 years. We analyze the performance development with the goal to test the adequacy of learning curves, and the skill acquisition theories they are based on, for describing and predicting expertise acquisition. On the one hand, we show that the skill acquisition theories implying a negative exponential learning curve do a better job in both describing early performance gains and predicting later trajectories of chess performance than those theories implying a power function learning curve. On the other hand, the learning curves of a large proportion of players show systematic qualitative deviations from the predictions of either type of skill acquisition theory. While skill acquisition theories predict larger performance gains in early years and smaller gains in later years, a substantial number of players begin to show substantial improvements with a delay of several years (and no improvement in the first years), deviations not fully accounted for by quantity of practice. The current work adds to the debate on how learning processes on a small time scale combine to large-scale changes.

  13. Signatures of Synchrotron: Low-cutoff X-ray emission and the hard X-ray spectrum of Cas A

    NASA Astrophysics Data System (ADS)

    Stage, Michael D.; Fedor, Emily Elizabeth; Martina-Hood, Hyourin

    2018-06-01

    In soft X-rays, bright, young Galactic remnants (Cas A, Kepler, Tycho, etc.) present thermal line emission and bremsstrahlung from ejecta, and synchrotron radiation from the shocks. Their hard X-ray spectra tend to be dominated by power-law sources. However, it can be non-trivial to discriminate between contributions from processes such as synchrotron and bremsstrahlung from nonthermally accelerated electrons, even though the energies of the electrons producing this radiation may be very different. Spatially-resolved spectroscopic analysis of 0.5-10 keV observations with, e.g., Chandracan provide leverage in identifying the processes and their locations. Previously, Stage & Allen (2006), Allen & Stage (2007) and Stage & Allen (2011) identified regions characterized by high-cutoff synchrotron radiation. Extrapolating synchrotron model fits to the emission in the Chandra band, they estimated the synchrotron contribution to the hard X-ray spectrum at about one-third the observed flux, fitting the balance with nonthermal bremsstrahlung emission produced by nonthermal electrons in the ejecta. Although it is unlikely this analysis missed regions of the highest-cutoff synchrotron emission, which supplies the bulk of the synchrotron above 15 keV, it may have missed regions of lower-cutoff emission, especially if they are near bright ejecta and the reverse shock. These regions cannot explain the emission at the highest energies (~50 keV), but may make significant contributions to the hard spectrum at lower energies (~10 keV). Using the technique described in Fedor, Martina-Hood & Stage (this meeting), we revisit the analysis to include regions that may be dominated by low-cutoff synchrotron, located in the interior of the remnant, and/or correlated with the reverse shock. Identifying X-ray emission from accelerated electrons associated with the reverse-shock would have important implications for synchrotron and non-thermal bremsstrahlung radiation above the 10 keV.

  14. SOLEIL shining on the solution-state structure of biomacromolecules by synchrotron X-ray footprinting at the Metrology beamline.

    PubMed

    Baud, A; Aymé, L; Gonnet, F; Salard, I; Gohon, Y; Jolivet, P; Brodolin, K; Da Silva, P; Giuliani, A; Sclavi, B; Chardot, T; Mercère, P; Roblin, P; Daniel, R

    2017-05-01

    Synchrotron X-ray footprinting complements the techniques commonly used to define the structure of molecules such as crystallography, small-angle X-ray scattering and nuclear magnetic resonance. It is remarkably useful in probing the structure and interactions of proteins with lipids, nucleic acids or with other proteins in solution, often better reflecting the in vivo state dynamics. To date, most X-ray footprinting studies have been carried out at the National Synchrotron Light Source, USA, and at the European Synchrotron Radiation Facility in Grenoble, France. This work presents X-ray footprinting of biomolecules performed for the first time at the X-ray Metrology beamline at the SOLEIL synchrotron radiation source. The installation at this beamline of a stopped-flow apparatus for sample delivery, an irradiation capillary and an automatic sample collector enabled the X-ray footprinting study of the structure of the soluble protein factor H (FH) from the human complement system as well as of the lipid-associated hydrophobic protein S3 oleosin from plant seed. Mass spectrometry analysis showed that the structural integrity of both proteins was not affected by the short exposition to the oxygen radicals produced during the irradiation. Irradiated molecules were subsequently analysed using high-resolution mass spectrometry to identify and locate oxidized amino acids. Moreover, the analyses of FH in its free state and in complex with complement C3b protein have allowed us to create a map of reactive solvent-exposed residues on the surface of FH and to observe the changes in oxidation of FH residues upon C3b binding. Studies of the solvent accessibility of the S3 oleosin show that X-ray footprinting offers also a unique approach to studying the structure of proteins embedded within membranes or lipid bodies. All the biomolecular applications reported herein demonstrate that the Metrology beamline at SOLEIL can be successfully used for synchrotron X-ray footprinting of biomolecules.

  15. Rapid biodiagnostic ex vivo imaging at 1 μm pixel resolution with thermal source FTIR FPA.

    PubMed

    Findlay, C R; Wiens, R; Rak, M; Sedlmair, J; Hirschmugl, C J; Morrison, Jason; Mundy, C J; Kansiz, M; Gough, K M

    2015-04-07

    A recent upgrade to the optics configuration of a thermal source FTIR microscope equipped with a focal plane array detector has enabled rapid acquisition of high magnification spectrochemical images, in transmission, with an effective geometric pixel size of ∼1 × 1 μm(2) at the sample plane. Examples, including standard imaging targets for scale and accuracy, as well as biomedical tissues and microorganisms, have been imaged with the new system and contrasted with data acquired at normal magnification and with a high magnification multi-beam synchrotron instrument. With this optics upgrade, one can now conduct rapid biodiagnostic ex vivo tissue imaging in-house, with images collected over larger areas, in less time (minutes) and with comparable quality and resolution to the best synchrotron source FTIR imaging capabilities.

  16. Attosecond light sources in the water window

    NASA Astrophysics Data System (ADS)

    Ren, Xiaoming; Li, Jie; Yin, Yanchun; Zhao, Kun; Chew, Andrew; Wang, Yang; Hu, Shuyuan; Cheng, Yan; Cunningham, Eric; Wu, Yi; Chini, Michael; Chang, Zenghu

    2018-02-01

    As a compact and burgeoning alternative to synchrotron radiation and free-electron lasers, high harmonic generation (HHG) has proven its superiority in static and time-resolved extreme ultraviolet spectroscopy for the past two decades and has recently gained many interests and successes in generating soft x-ray emissions covering the biologically important water window spectral region. Unlike synchrotron and free-electron sources, which suffer from relatively long pulse width or large time jitter, soft x-ray sources from HHG could offer attosecond time resolution and be synchronized with their driving field to investigate time-resolved near edge absorption spectroscopy, which could reveal rich structural and dynamical information of the interrogated samples. In this paper, we review recent progresses on generating and characterizing attosecond light sources in the water window region. We show our development of an energetic, two-cycle, carrier-envelope phase stable laser source at 1.7 μm and our achievement in producing a 53 as soft x-ray pulse covering the carbon K-edge in the water window. Such source paves the ways for the next generation x-ray spectroscopy with unprecedented temporal resolution.

  17. Diamond Light Source: status and perspectives.

    PubMed

    Materlik, Gerhard; Rayment, Trevor; Stuart, David I

    2015-03-06

    Diamond Light Source, a third-generation synchrotron radiation (SR) facility in the UK, celebrated its 10th anniversary in 2012. A private limited company was set up in April 2002 to plan, construct and operate the new user-oriented SR facility, called in brief Diamond. It succeeded the Synchrotron Radiation Source in Daresbury, a second-generation synchrotron that opened in 1980 as the world's first dedicated X-ray-providing facility, closing finally in 2008, by which time Diamond's accelerators and first beamlines were operating and user experiments were under way. This theme issue of Philosophical Transactions of the Royal Society A gives some examples of the rich diversity of research done in the initial five years, with some glimpses of activity up to 2014. Speakers at the 10 year anniversary symposium were drawn from a small number of major thematic areas and each theme was elaborated by a few speakers whose contributions were placed into a broader context by a leading member of the UK academic community in the role of rapporteur. This introduction gives a summary of the design choices and strategic planning of Diamond as a coherent user facility, a snapshot of its present status and some consideration of future perspectives. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

  18. Observations of a nearby filament of galaxy clusters with the Sardinia Radio Telescope

    NASA Astrophysics Data System (ADS)

    Vacca, Valentina; Murgia, M.; Loi, F. Govoni F.; Vazza, F.; Finoguenov, A.; Carretti, E.; Feretti, L.; Giovannini, G.; Concu, R.; Melis, A.; Gheller, C.; Paladino, R.; Poppi, S.; Valente, G.; Bernardi, G.; Boschin, W.; Brienza, M.; Clarke, T. E.; Colafrancesco, S.; Enßlin, T.; Ferrari, C.; de Gasperin, F.; Gastaldello, F.; Girardi, M.; Gregorini, L.; Johnston-Hollitt, M.; Junklewitz, H.; Orrù, E.; Parma, P.; Perley, R.; Taylor, G. B.

    2018-05-01

    We report the detection of diffuse radio emission which might be connected to a large-scale filament of the cosmic web covering a 8° × 8° area in the sky, likely associated with a z≈0.1 over-density traced by nine massive galaxy clusters. In this work, we present radio observations of this region taken with the Sardinia Radio Telescope. Two of the clusters in the field host a powerful radio halo sustained by violent ongoing mergers and provide direct proof of intra-cluster magnetic fields. In order to investigate the presence of large-scale diffuse radio synchrotron emission in and beyond the galaxy clusters in this complex system, we combined the data taken at 1.4 GHz with the Sardinia Radio Telescope with higher resolution data taken with the NRAO VLA Sky Survey. We found 28 candidate new sources with a size larger and X-ray emission fainter than known diffuse large-scale synchrotron cluster sources for a given radio power. This new population is potentially the tip of the iceberg of a class of diffuse large-scale synchrotron sources associated with the filaments of the cosmic web. In addition, we found in the field a candidate new giant radio galaxy.

  19. Brookhaven highlights for fiscal year 1991, October 1, 1990--September 30, 1991

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rowe, M.S.; Cohen, A.; Greenberg, D.

    1991-12-31

    This report highlights Brookhaven National Laboratory`s activities for fiscal year 1991. Topics from the four research divisions: Computing and Communications, Instrumentation, Reactors, and Safety and Environmental Protection are presented. The research programs at Brookhaven are diverse, as is reflected by the nine different scientific departments: Accelerator Development, Alternating Gradient Synchrotron, Applied Science, Biology, Chemistry, Medical, National Synchrotron Light Source, Nuclear Energy, and Physics. Administrative and managerial information about Brookhaven are also disclosed. (GHH)

  20. Brookhaven highlights for fiscal year 1991, October 1, 1990--September 30, 1991

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rowe, M.S.; Cohen, A.; Greenberg, D.

    1991-01-01

    This report highlights Brookhaven National Laboratory's activities for fiscal year 1991. Topics from the four research divisions: Computing and Communications, Instrumentation, Reactors, and Safety and Environmental Protection are presented. The research programs at Brookhaven are diverse, as is reflected by the nine different scientific departments: Accelerator Development, Alternating Gradient Synchrotron, Applied Science, Biology, Chemistry, Medical, National Synchrotron Light Source, Nuclear Energy, and Physics. Administrative and managerial information about Brookhaven are also disclosed. (GHH)

  1. Method and devices for performing stereotactic microbeam radiation therapy

    DOEpatents

    Dilmanian, F. Avraham

    2010-01-05

    A radiation delivery system generally includes either a synchrotron source or a support frame and a plurality of microbeam delivery devices supported on the support frame, both to deliver a beam in a hemispherical arrangement. Each of the microbeam delivery devices or synchrotron irradiation ports is adapted to deliver at least one microbeam of radiation along a microbeam delivery axis, wherein the microbeam delivery axes of the plurality of microbeam delivery devices cross within a common target volume.

  2. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Meyer, Eileen T.; Breiding, Peter; Georganopoulos, Markos

    The Chandra X-ray observatory has discovered several dozen anomalously X-ray-bright jets associated with powerful quasars. A popular explanation for the X-ray flux from the knots in these jets is that relativistic synchrotron-emitting electrons inverse-Compton scatter cosmic microwave background (CMB) photons to X-ray energies (the IC/CMB model). This model predicts a high gamma-ray flux that should be detectable by the Fermi /Large Area Telescope (LAT) for many sources. GeV-band upper limits from Fermi /LAT for the well-known anomalous X-ray jet in PKS 0637−752 were previously shown in Meyer et al. to violate the predictions of the IC/CMB model. Previously, measurements ofmore » the jet synchrotron spectrum, important for accurately predicting the gamma-ray flux level, were lacking between radio and infrared wavelengths. Here, we present new Atacama Large Millimeter/submillimeter Array (ALMA) observations of the large-scale jet at 100, 233, and 319 GHz, which further constrain the synchrotron spectrum, supporting the previously published empirical model. We also present updated limits from the Fermi /LAT using the new “Pass 8” calibration and approximately 30% more time on source. With these deeper limits, we rule out the IC/CMB model at the 8.7 σ level. Finally, we demonstrate that complete knowledge of the synchrotron SED is critical in evaluating the IC/CMB model.« less

  3. Cluster Analysis of Childhood Temperament Data on Adoptees.

    ERIC Educational Resources Information Center

    Maurer, Ralph; And Others

    1980-01-01

    Results concur with the Thomas-Chess findings in identifying three main temperament groups: difficult, easy, and slow to warm up. Membership in the difficult group predicted later childhood behavior disorder in both sexes. (Author)

  4. Air Pollution Affects Community Health

    ERIC Educational Resources Information Center

    Shy, Carl M.; Finklea, John F.

    1973-01-01

    Community Health and Environmental Surveillance System (CHESS), a nationwide program relating community health to environmental quality, is designed to evaluate existing environmental standards, obtain health intelligence for new standards, and document health benefits of air pollution control. (BL)

  5. Diffusion weighted whole body imaging with background body signal suppression (DWIBS): technical improvement using free breathing, STIR and high resolution 3D display.

    PubMed

    Takahara, Taro; Imai, Yutaka; Yamashita, Tomohiro; Yasuda, Seiei; Nasu, Seiji; Van Cauteren, Marc

    2004-01-01

    To examine a new way of body diffusion weighted imaging (DWI) using the short TI inversion recovery-echo planar imaging (STIR-EPI) sequence and free breathing scanning (diffusion weighted whole body imaging with background body signal suppression; DWIBS) to obtain three-dimensional displays. 1) Apparent contrast-to-noise ratios (AppCNR) between lymph nodes and surrounding fat tissue were compared in three types of DWI with and without breath-holding, with variable lengths of scan time and slice thickness. 2) The STIR-EPI sequence and spin echo-echo planar imaging (SE-EPI) sequence with chemical shift selective (CHESS) pulse were compared in terms of their degree of fat suppression. 3) Eleven patients with neck, chest, and abdominal malignancy were scanned with DWIBS for evaluation of feasibility. Whole body imaging was done in a later stage of the study using the peripheral vascular coil. The AppCNR of 8 mm slice thickness images reconstructed from 4 mm slice thickness source images obtained in a free breathing scan of 430 sec were much better than 9 mm slice thickness breath-hold scans obtained in 25 sec. High resolution multi-planar reformat (MPR) and maximum intensity projection (MIP) images could be made from the data set of 4 mm slice thickness images. Fat suppression was much better in the STIR-EPI sequence than SE-EPI with CHESS pulse. The feasibility of DWIBS was showed in clinical scans of 11 patients. Whole body images were successfully obtained with adequate fat suppression. Three-dimensional DWIBS can be obtained with this technique, which may allow us to screen for malignancies in the whole body.

  6. New synchrotron powder diffraction facility for long-duration experiments

    PubMed Central

    Murray, Claire A.; Potter, Jonathan; Day, Sarah J.; Baker, Annabelle R.; Thompson, Stephen P.; Kelly, Jon; Morris, Christopher G.; Tang, Chiu C.

    2017-01-01

    A new synchrotron X-ray powder diffraction instrument has been built and commissioned for long-duration experiments on beamline I11 at Diamond Light Source. The concept is unique, with design features to house multiple experiments running in parallel, in particular with specific stages for sample environments to study slow kinetic systems or processes. The instrument benefits from a high-brightness X-ray beam and a large area detector. Diffraction data from the commissioning work have shown that the objectives and criteria are met. Supported by two case studies, the results from months of measurements have demonstrated the viability of this large-scale instrument, which is the world’s first dedicated facility for long-term studies (weeks to years) using synchrotron radiation. PMID:28190992

  7. Three-dimensional monochromatic x-ray computed tomography using synchrotron radiation

    NASA Astrophysics Data System (ADS)

    Saito, Tsuneo; Kudo, Hiroyuki; Takeda, Tohoru; Itai, Yuji; Tokumori, Kenji; Toyofuku, Fukai; Hyodo, Kazuyuki; Ando, Masami; Nishimura, Katsuyuki; Uyama, Chikao

    1998-08-01

    We describe a technique of 3D computed tomography (3D CT) using monochromatic x rays generated by synchrotron radiation, which performs a direct reconstruction of a 3D volume image of an object from its cone-beam projections. For the development, we propose a practical scanning orbit of the x-ray source to obtain complete 3D information on an object, and its corresponding 3D image reconstruction algorithm. The validity and usefulness of the proposed scanning orbit and reconstruction algorithm were confirmed by computer simulation studies. Based on these investigations, we have developed a prototype 3D monochromatic x-ray CT using synchrotron radiation, which provides exact 3D reconstruction and material-selective imaging by using the K-edge energy subtraction technique.

  8. Fevers and Chills: Separating thermal and synchrotron components in SNR spectra

    NASA Astrophysics Data System (ADS)

    Fedor, Emily Elizabeth; Martina-Hood, Hyourin; Stage, Michael D.

    2018-06-01

    Spatially-resolved spectroscopy is an extremely powerful tool in X-ray analysis of extended sources, but can be computationally difficult if a source exhibits complex morphology. For example, high-resolution Chandra data of bright Galactic supernova remnants (Cas A, Tycho, etc.) allow extractions of high-quality spectra from tens to hundreds of thousands of regions, providing a rich laboratory for localizing emission from processes such as thermal line emission, bremsstrahlung, and synchrotron. This soft-band analysis informs our understanding of the typically nonthermal hard X-ray emission observed with other lower-resolution instruments. The analysis is complicated by both projection effects and the presence of multiple emission mechanisms in some regions. In particular, identifying regions with significant nonthermal emission is critical to understanding acceleration processes in remnants. Fitting tens of thousands of regions with complex, multi-component models can be time-consuming and involve so many free parameters that little constraint can be placed on the values. Previous work by Stage & Allen ('06, '07, '11) on Cas A used a technique to identify regions dominated by the highest-cutoff synchrotron emission by fitting with a simple thermal emission model and identifying regions with anomalously high apparent temperatures (caused by presence of the high-energy tail of the synchrotron emission component). Here, we present a similar technique. We verify the previous approach and, more importantly, expand it to include a method to identify regions containing strong lower-cutoff synchrotron radiation. Such regions might be associated with the reverse-shock of a supernova. Identification of a nonthermal electron population in the interior of an SNR would have significant implications for the energy balance and emission mechanisms producing the high-energy (> 10 keV) spectrum.

  9. SESAME - A 3rd Generation Synchrotron Light Source for the Middle East

    NASA Astrophysics Data System (ADS)

    U˝Lkü, Dinçer; Rahighi, Javad; Winick, Herman

    2007-01-01

    SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East) will be the Middle East's first international research center. It is a cooperative venture by the scientists and governments of the region with founding members Bahrain, Egypt, Israel, Jordan, Pakistan, Palestine Authority, and Turkey. Iran is in the process of finalizing its formal membership. Other countries (Cyprus, Morocco, and the United Arab Emirates) are also expected to join. The permanent Council of member states has full responsibility for the project. Members provide the annual operating budget. Observer countries are Germany, Greece, Italy, Kuwait, Portugal, Russian Federation, Sweden, the UK, and the US. SESAME is being developed under the umbrella of UNESCO. Jordan was selected as the building site. SESAME will offer excellent opportunities for training of Middle East scientists and attract those working abroad to consider returning. SESAME will be a 2.5GeV 3rd Generation light source (emittance 26nm-rad, circumference ~133m), providing excellent performance for structural molecular biology, molecular environmental science, surface and interface science, microelectromechanical devices, x-ray imaging, archaeological microanalysis, and materials characterization. It will cover a broad spectral range from the infrared to hard x-rays and will have 12 straight sections for insertion devices (average length 2.75m). The injector will be the BESSY I 0.8 GeV booster synchrotron which has been given as a gift from Germany. Four committees advise the Council and assist in developing the technical design, beam lines, user community, and scientific Program. The SESAME building, now in construction with funds and a site provided by Jordan, is scheduled for completion in late 2006 after which the BESSY I injector will be installed. First stored beam in the new 2.5 GeV ring is planned for 2009 with six initial beamlines planned. Some beamlines will be built by member countries. Additional funds to purchase components of the new ring and beamlines are being sought from the EU, the US, and other sources. SESAME has benefited greatly from offers by other light source facilities of equipment and training fellowships in both accelerator technology and applications of synchrotron radiation. Details of this, and other aspects of the training program, are given below. It is hoped that in the future fellowship offers will continue to be made by many light source laboratories to further increase the level of experience with accelerator technology and synchrotron light science in preparation for the start of operation of SESAME.

  10. SESAME — A 3rd Generation Synchrotron Light Source for the Middle East

    NASA Astrophysics Data System (ADS)

    Űlkü, Dinçer; Rahighi, Javad; Winick, Herman

    2007-01-01

    SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East) will be the Middle East's first international research center. It is a cooperative venture by the scientists and governments of the region with founding members Bahrain, Egypt, Israel, Jordan, Pakistan, Palestine Authority, and Turkey. Iran is in the process of finalizing its formal membership. Other countries (Cyprus, Morocco, and the United Arab Emirates) are also expected to join. The permanent Council of member states has full responsibility for the project. Members provide the annual operating budget. Observer countries are Germany, Greece, Italy, Kuwait, Portugal, Russian Federation, Sweden, the UK, and the US. SESAME is being developed under the umbrella of UNESCO. Jordan was selected as the building site. SESAME will offer excellent opportunities for training of Middle East scientists and attract those working abroad to consider returning. SESAME will be a 2.5GeV 3rd Generation light source (emittance 26nm-rad, circumference ˜133m), providing excellent performance for structural molecular biology, molecular environmental science, surface and interface science, microelectromechanical devices, x-ray imaging, archaeological microanalysis, and materials characterization. It will cover a broad spectral range from the infrared to hard x-rays and will have 12 straight sections for insertion devices (average length 2.75m). The injector will be the BESSY I 0.8 GeV booster synchrotron which has been given as a gift from Germany. Four committees advise the Council and assist in developing the technical design, beam lines, user community, and scientific Program. The SESAME building, now in construction with funds and a site provided by Jordan, is scheduled for completion in late 2006 after which the BESSY I injector will be installed. First stored beam in the new 2.5 GeV ring is planned for 2009 with six initial beamlines planned. Some beamlines will be built by member countries. Additional funds to purchase components of the new ring and beamlines are being sought from the EU, the US, and other sources. SESAME has benefited greatly from offers by other light source facilities of equipment and training fellowships in both accelerator technology and applications of synchrotron radiation. Details of this, and other aspects of the training program, are given below. It is hoped that in the future fellowship offers will continue to be made by many light source laboratories to further increase the level of experience with accelerator technology and synchrotron light science in preparation for the start of operation of SESAME.

  11. SESAME - A 3rd Generation Synchrotron Light Source for the Middle East

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ulkue, Dincer; Rahighi, Javad; Winick, Herman

    2007-01-19

    SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East) will be the Middle East's first international research center. It is a cooperative venture by the scientists and governments of the region with founding members Bahrain, Egypt, Israel, Jordan, Pakistan, Palestine Authority, and Turkey. Iran is in the process of finalizing its formal membership. Other countries (Cyprus, Morocco, and the United Arab Emirates) are also expected to join. The permanent Council of member states has full responsibility for the project. Members provide the annual operating budget. Observer countries are Germany, Greece, Italy, Kuwait, Portugal, Russian Federation, Sweden, the UK,more » and the US. SESAME is being developed under the umbrella of UNESCO. Jordan was selected as the building site. SESAME will offer excellent opportunities for training of Middle East scientists and attract those working abroad to consider returning. SESAME will be a 2.5GeV 3rd Generation light source (emittance 26nm-rad, circumference {approx}133m), providing excellent performance for structural molecular biology, molecular environmental science, surface and interface science, microelectromechanical devices, x-ray imaging, archaeological microanalysis, and materials characterization. It will cover a broad spectral range from the infrared to hard x-rays and will have 12 straight sections for insertion devices (average length 2.75m). The injector will be the BESSY I 0.8 GeV booster synchrotron which has been given as a gift from Germany. Four committees advise the Council and assist in developing the technical design, beam lines, user community, and scientific Program. The SESAME building, now in construction with funds and a site provided by Jordan, is scheduled for completion in late 2006 after which the BESSY I injector will be installed. First stored beam in the new 2.5 GeV ring is planned for 2009 with six initial beamlines planned. Some beamlines will be built by member countries. Additional funds to purchase components of the new ring and beamlines are being sought from the EU, the US, and other sources. SESAME has benefited greatly from offers by other light source facilities of equipment and training fellowships in both accelerator technology and applications of synchrotron radiation. Details of this, and other aspects of the training program, are given below. It is hoped that in the future fellowship offers will continue to be made by many light source laboratories to further increase the level of experience with accelerator technology and synchrotron light science in preparation for the start of operation of SESAME.« less

  12. Compton scattering of self-absorbed synchrotron emission

    NASA Astrophysics Data System (ADS)

    Gao, He; Lei, Wei-Hua; Wu, Xue-Feng; Zhang, Bing

    2013-11-01

    Synchrotron self-Compton (SSC) scattering is an important emission mechanism in many astronomical sources, such as gamma-ray bursts (GRBs) and active galactic nuclei. We give a complete presentation of the analytical approximations for the Compton scattering of synchrotron emission with both weak and strong synchrotron self-absorption. All possible orders of the characteristic synchrotron spectral breaks (νa, νm and νc) are studied. In the weak self-absorption regime, i.e. νa < νc, the electron energy distribution is not modified by the self-absorption process. The shape of the SSC component broadly resembles that of synchrotron, but with the following features: The SSC flux increases linearly with frequency up to the SSC break frequency corresponding to the self-absorption frequency νa; and the presence of a logarithmic term in the high-frequency range of the SSC spectra makes it harder than the power-law approximation. In the strong absorption regime, i.e. νa > νc, heating of low-energy electrons due to synchrotron absorption leads to pile-up of electrons, and form a thermal component besides the broken power-law component. This leads to two-component (thermal + non-thermal) spectra for both the synchrotron and SSC spectral components. For νc < νa < νm, the spectrum is thermal (non-thermal) dominated if ν _a > √{ν _m ν _c} (ν _a < √{ν _m ν _c}). Similar to the weak-absorption regime, the SSC spectral component is broader than the simple broken power-law approximation. We derive the critical condition for strong absorption (electron pile-up), and discuss a case of GRB reverse shock emission in a wind medium, which invokes νa > max(νm, νc).

  13. Brookhaven National Laboratory

    MedlinePlus

    ... Sciences Center for Functional Nanomaterials Chemistry Condensed Matter Physics & Materials Science National Synchrotron Light Source II Sustainable ... and Technology Nonproliferation and National Security Nuclear & Particle ... Magnet RIKEN BNL ...

  14. Is the GeV-TeV emission of PKS 0447-439 from the proton synchrotron radiation?

    NASA Astrophysics Data System (ADS)

    Gao, Quan-Gui; Lu, Fang-Wu; Ma, Ju; Ren, Ji-Yang; Li, Huai-Zhen

    2018-06-01

    We study the multi-wavelength emission features of PKS 0447-439 in the frame of the one-zone homogeneous lepto-hadronic model. In this model, we assumed that the steady power-laws with exponential cut-offs distributions of protons and electrons are injected into the source. The non-linear time-dependent kinematic equations, describing the evolution of protons, electrons and photons, are defined; these equations self-consistently involve synchrotron radiation of protons, photon-photon interaction, synchrotron radiation of electron/positron pairs, inverse Compton scattering and synchrotron self-absorption. The model is applied to reproduce the multi-wavelength spectrum of PKS 0447-439. Our results indicate that the spectral energy distribution (SED) of PKS 0447-439 can be reproduced well by the model. In particular, the GeV-TeV emission is produced by the synchrotron radiation of relativistic protons. The physically plausible solutions require the magnetic strength 10 G≲ B ≲ 100 G. We found that the observed spectrum of PKS 0447-439 can be reproduced well by the model whether z = 0.16 or z = 0.2, and the acceptable upper limit of redshift is z=0.343.

  15. PREFACE Preface

    NASA Astrophysics Data System (ADS)

    Sakurai, Kazuo; Takahara, Atsushi

    2011-01-01

    This special issue contains peer-reviewed invited and contributed papers that were presented at The International Symposium on 'Future Trend in Soft Material Research with Advanced Light Source: Interdisciplinary of Bio- & Synthetic- Materials and Industrial Transferring', which was held in SPring-8, Japan, on September 1-3, 2010. Advanced light sources including neutron and synchrotron are becoming increasingly critical to the study of soft materials. This cutting-edge analytical tool is expected to lead to the creation of new materials with revolutionary properties and functions. At SPring-8, a new beam line dedicated to soft materials has now been launched as one of the most powerful X-rays for scattering and diffraction. Additionally, the next-generation light source, XFEL (X-ray Free Electron Laser), facilities are currently being developed in several locations. In the near future, femto-second and coherent X-ray sources will be available in soft material research and should reveal the various new aspects of advanced soft material research and technology. On the occasion of the third fiscal year of the CREST (project leader: Kazuo Sakurai) and ERATO (project leader: Atsushi Takahara) projects, we organized this international symposium in order to accelerate the discussion among global-level researchers working on next-generation synchrotron radiation science, biophysics and supramolecular science, modern surface science in soft materials, and industrial applications of neutron and synchrotron radiation sources. In this symposium 21 oral presentations, including 8 invited speakers from abroad, and 40 poster presentations from USA, France, Korea, Taiwan, and Japan were presented during the three day symposium. The symposium chairs reviewed the poster presentations by young scientists, and eight young researchers received the Award for Best Poster Presentation. We sincerely hope that these proceedings will be beneficial in future applications of advanced light sources to soft materials science and technology, not only to our ERATO and CREST projects, but also to the research of all the participants, broadening our scientific horizons. Kazuo Sakurai & Atsushi TakaharaSymposium Chairs Symposium Organization and Committee Supported by: Japan Science and Technology Agency (JST) Japan Synchrotron Radiation Research Institute (JASRI) Co-sponsored by: Society of Japan Polymer Science Japanese Society of Synchrotron Radiation Research Advanced Softmaterial Beamline Consortium Symposium Chairs: Atsushi Takahara (Kyushu University, JST, ERATO) Kazuo Sakurai (Univ. Kitakyushu, JST, CREST) Organizing Committee: Yoshiyuki Amemiya (The Univ. of Tokyo, JST, CREST) Naoto Yagi (JASRI, JST, CREST) Masaki Takata (JASRI) Isamu Akiba (Univ. Kitakyushu, JST, CREST) Yuya Shinohara (The Univ. of Tokyo, JST, CREST) Taiki Hoshino (Kyushu University, JST, ERATO) Jun-ichi Imuta (Kyushu University, JST, ERATO) Moriya Kikuchi (Kyushu University, JST, ERATO) Motoyasu Kobayashi (Kyushu University, JST, ERATO) Group photograph Group photograph Lecture meeting Lecture meeting

  16. Low-aberration beamline optics for synchrotron infrared nanospectroscopy.

    PubMed

    Freitas, Raul O; Deneke, Christoph; Maia, Francisco C B; Medeiros, Helton G; Moreno, Thierry; Dumas, Paul; Petroff, Yves; Westfahl, Harry

    2018-04-30

    Synchrotron infrared nanospectroscopy is a recently developed technique that enables new possibilities in the broadband chemical analysis of materials in the nanoscale, far beyond the diffraction limit in this frequency domain. Synchrotron infrared ports have exploited mainly the high brightness advantage provided by electron storage rings across the whole infrared range. However, optical aberrations in the beam produced by the source depth of bending magnet emission at large angles prevent infrared nanospectroscopy to reach its maximum capability. In this work we present a low-aberration optical layout specially designed and constructed for a dedicated synchrotron infrared nanospectroscopy beamline. We report excellent agreement between simulated beam profiles (from standard wave propagation and raytracing optics simulations) with experimental measurements. We report an important improvement in the infrared nanospectroscopy experiment related to the improved beamline optics. Finally, we demonstrate the performance of the nanospectroscopy endstation by measuring a hyperspectral image of a polar material and we evaluate the setup sensitivity by measuring ultra-thin polymer films down to 6 nm thick.

  17. Modeling challenges and approaches in simulating the Jovian synchrotron radiation belts from an in-situ perspective

    NASA Astrophysics Data System (ADS)

    Adumitroaie, V.; Oyafuso, F. A.; Levin, S.; Gulkis, S.; Janssen, M. A.; Santos-Costa, D.; Bolton, S. J.

    2017-12-01

    In order to obtain credible atmospheric composition retrieval values from Jupiter's observed radiative signature via Juno's MWR instrument, it is necessary to separate as robustly as possible the contributions from three emission sources: CMB, planet and synchrotron radiation belts. The numerical separation requires a refinement, based on the in-situ data, of a higher fidelity model for the synchrotron emission, namely the multi-parameter, multi-zonal model of Levin at al. (2001). This model employs an empirical electron energy distribution, which prior to the Juno mission, has been adjusted exclusively from VLA observations. At minimum 8 sets of perijove observations (i.e. by PJ9) have to be delivered to an inverse model for retrieval of the electron distribution parameters with the goal of matching the synchrotron emission observed along MWR's lines of sight. The challenges and approaches taken to perform this task are discussed here. The model will be continuously improved with the availability of additional information, both from the MWR and magnetometer instruments.

  18. Thermal Electrons in Gamma-Ray Burst Afterglows

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ressler, Sean M.; Laskar, Tanmoy

    2017-08-20

    To date, nearly all multi-wavelength modeling of long-duration γ -ray bursts has ignored synchrotron radiation from the significant population of electrons expected to pass the shock without acceleration into a power-law distribution. We investigate the effect of including the contribution of thermal, non-accelerated electrons to synchrotron absorption and emission in the standard afterglow model, and show that these thermal electrons provide an additional source of opacity to synchrotron self-absorption, and yield an additional emission component at higher energies. The extra opacity results in an increase in the synchrotron self-absorption frequency by factors of 10–100 for fiducial parameters. The nature ofmore » the additional emission depends on the details of the thermal population, but is generally observed to yield a spectral peak in the optical brighter than radiation from the nonthermal population by similar factors a few seconds after the burst, remaining detectable at millimeter and radio frequencies several days later.« less

  19. Pump-probe experiments at the TEMPO beamline using the low-α operation mode of Synchrotron SOLEIL.

    PubMed

    Silly, Mathieu G; Ferté, Tom; Tordeux, Marie Agnes; Pierucci, Debora; Beaulieu, Nathan; Chauvet, Christian; Pressacco, Federico; Sirotti, Fausto; Popescu, Horia; Lopez-Flores, Victor; Tortarolo, Marina; Sacchi, Maurizio; Jaouen, Nicolas; Hollander, Philippe; Ricaud, Jean Paul; Bergeard, Nicolas; Boeglin, Christine; Tudu, Bharati; Delaunay, Renaud; Luning, Jan; Malinowski, Gregory; Hehn, Michel; Baumier, Cédric; Fortuna, Franck; Krizmancic, Damjan; Stebel, Luigi; Sergo, Rudi; Cautero, Giuseppe

    2017-07-01

    The SOLEIL synchrotron radiation source is regularly operated in special filling modes dedicated to pump-probe experiments. Among others, the low-α mode operation is characterized by shorter pulse duration and represents the natural bridge between 50 ps synchrotron pulses and femtosecond experiments. Here, the capabilities in low-α mode of the experimental set-ups developed at the TEMPO beamline to perform pump-probe experiments with soft X-rays based on photoelectron or photon detection are presented. A 282 kHz repetition-rate femtosecond laser is synchronized with the synchrotron radiation time structure to induce fast electronic and/or magnetic excitations. Detection is performed using a two-dimensional space resolution plus time resolution detector based on microchannel plates equipped with a delay line. Results of time-resolved photoelectron spectroscopy, circular dichroism and magnetic scattering experiments are reported, and their respective advantages and limitations in the framework of high-time-resolution pump-probe experiments compared and discussed.

  20. Ultra high-speed x-ray imaging of laser-driven shock compression using synchrotron light

    NASA Astrophysics Data System (ADS)

    Olbinado, Margie P.; Cantelli, Valentina; Mathon, Olivier; Pascarelli, Sakura; Grenzer, Joerg; Pelka, Alexander; Roedel, Melanie; Prencipe, Irene; Laso Garcia, Alejandro; Helbig, Uwe; Kraus, Dominik; Schramm, Ulrich; Cowan, Tom; Scheel, Mario; Pradel, Pierre; De Resseguier, Thibaut; Rack, Alexander

    2018-02-01

    A high-power, nanosecond pulsed laser impacting the surface of a material can generate an ablation plasma that drives a shock wave into it; while in situ x-ray imaging can provide a time-resolved probe of the shock-induced material behaviour on macroscopic length scales. Here, we report on an investigation into laser-driven shock compression of a polyurethane foam and a graphite rod by means of single-pulse synchrotron x-ray phase-contrast imaging with MHz frame rate. A 6 J, 10 ns pulsed laser was used to generate shock compression. Physical processes governing the laser-induced dynamic response such as elastic compression, compaction, pore collapse, fracture, and fragmentation have been imaged; and the advantage of exploiting the partial spatial coherence of a synchrotron source for studying low-density, carbon-based materials is emphasized. The successful combination of a high-energy laser and ultra high-speed x-ray imaging using synchrotron light demonstrates the potentiality of accessing complementary information from scientific studies of laser-driven shock compression.

  1. Prospects for compact high-intensity laser synchrotron x-ray and gamma sources

    NASA Astrophysics Data System (ADS)

    Pogorelsky, I. V.

    1997-03-01

    A laser interacting with a relativistic electron beam behaves like a virtual wiggler of an extremely short period equal to half of the laser wavelength. This approach opens a route to relatively compact, high-brightness x-ray sources alternative or complementary to conventional synchrotron light sources. Although not new, the laser synchrotron source (LSS) concept is still waiting for a convincing demonstration. Available at the BNL Accelerator Test Facility (ATF), a high-brightness electron beam and the high-power CO2 laser may be used for prototype LSS demonstration. In a feasible demonstration experiment, 10-GW, 100-ps CO2 laser beam will be brought to a head-on collision with a 10-ps, 0.5-nC, 50 MeV electron bunch. Flashes of collimated 4.7 keV (2.6 Å) x-rays of 10-ps pulse duration, with a flux of ˜1019photons/sec, will be produced via linear Compton backscattering. The x-ray spectrum is tunable proportionally to the e-beam energy. A rational short-term extension of the proposed experiment would be further enhancement of the x-ray flux to the 1022 photons/sec level, after the ongoing ATF CO2 laser upgrade to 5 TW peak power and electron bunch shortening to 3 ps is realized. In the future, exploiting the promising approach of a high-gradient laser wake field accelerator, a compact "table-top" LSS of monochromatic gamma radiation may become feasible.

  2. Real-time data-intensive computing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Parkinson, Dilworth Y., E-mail: dyparkinson@lbl.gov; Chen, Xian; Hexemer, Alexander

    2016-07-27

    Today users visit synchrotrons as sources of understanding and discovery—not as sources of just light, and not as sources of data. To achieve this, the synchrotron facilities frequently provide not just light but often the entire end station and increasingly, advanced computational facilities that can reduce terabytes of data into a form that can reveal a new key insight. The Advanced Light Source (ALS) has partnered with high performance computing, fast networking, and applied mathematics groups to create a “super-facility”, giving users simultaneous access to the experimental, computational, and algorithmic resources to make this possible. This combination forms an efficientmore » closed loop, where data—despite its high rate and volume—is transferred and processed immediately and automatically on appropriate computing resources, and results are extracted, visualized, and presented to users or to the experimental control system, both to provide immediate insight and to guide decisions about subsequent experiments during beamtime. We will describe our work at the ALS ptychography, scattering, micro-diffraction, and micro-tomography beamlines.« less

  3. The role of meaning in contextual cueing: evidence from chess expertise.

    PubMed

    Brockmole, James R; Hambrick, David Z; Windisch, David J; Henderson, John M

    2008-01-01

    In contextual cueing, the position of a search target is learned over repeated exposures to a visual display. The strength of this effect varies across stimulus types. For example, real-world scene contexts give rise to larger search benefits than contexts composed of letters or shapes. We investigated whether such differences in learning can be at least partially explained by the degree of semantic meaning associated with a context independently of the nature of the visual information available (which also varies across stimulus types). Chess boards served as the learning context as their meaningfulness depends on the observer's knowledge of the game. In Experiment 1, boards depicted actual game play, and search benefits for repeated boards were 4 times greater for experts than for novices. In Experiment 2, search benefits among experts were halved when less meaningful randomly generated boards were used. Thus, stimulus meaningfulness independently contributes to learning context-target associations.

  4. At the Cosmonaut Hotel in Baikonur, Kazakhstan, Expedition 48-49 prime crewmember Kate Rubins of NASA (left) and her backup, NASA���s Peggy Whitson (right) share a game of chess June 30 during pre-launch activities. Rubins, Anatoly Ivanishin of Roscosmos and Takuya Onishi of the Japan Aerospace Exploration Agency, will launch July 7, Baikonur time, on the Soyuz MS-01 spacecraft for a planned four-month mission on the International Space Station...NASA/Alexander Vysotsky.

    NASA Image and Video Library

    2016-06-30

    At the Cosmonaut Hotel in Baikonur, Kazakhstan, Expedition 48-49 prime crewmember Kate Rubins of NASA (left) and her backup, NASA’s Peggy Whitson (right) share a game of chess June 30 during pre-launch activities. Rubins, Anatoly Ivanishin of Roscosmos and Takuya Onishi of the Japan Aerospace Exploration Agency, will launch July 7, Baikonur time, on the Soyuz MS-01 spacecraft for a planned four-month mission on the International Space Station. NASA/Alexander Vysotsky

  5. Impedance measurements of the extraction kicker system for the rapid cycling synchrotron of China Spallation Neutron Source

    NASA Astrophysics Data System (ADS)

    Huang, Liang-Sheng; Wang, Sheng; Liu, Yu-Dong; Li, Yong; Liu, Ren-Hong; Xiao, Ou-Zheng

    2016-04-01

    The fast extraction kicker system is one of the most important accelerator components and the main source of impedance in the Rapid Cycling Synchrotron of the China Spallation Neutron Source. It is necessary to understand the kicker impedance before its installation into the tunnel. Conventional and improved wire methods are employed in the impedance measurement. The experimental results for the kicker impedance are explained by comparison with simulation using CST PARTICLE STUDIO. The simulation and measurement results confirm that the window-frame ferrite geometry and the end plate are the important structures causing coupling impedance. It is proved in the measurements that the mismatching from the power form network to the kicker leads to a serious oscillation sideband of the longitudinal and vertical impedance and the oscillation can be reduced by ferrite absorbing material. Supported by National Natural Science Foundation of China (11175193, 11275221)

  6. Emphysema diagnosis using X-ray dark-field imaging at a laser-driven compact synchrotron light source

    PubMed Central

    Schleede, Simone; Meinel, Felix G.; Bech, Martin; Herzen, Julia; Achterhold, Klaus; Potdevin, Guillaume; Malecki, Andreas; Adam-Neumair, Silvia; Thieme, Sven F.; Bamberg, Fabian; Nikolaou, Konstantin; Bohla, Alexander; Yildirim, Ali Ö.; Loewen, Roderick; Gifford, Martin; Ruth, Ronald; Eickelberg, Oliver; Reiser, Maximilian; Pfeiffer, Franz

    2012-01-01

    In early stages of various pulmonary diseases, such as emphysema and fibrosis, the change in X-ray attenuation is not detectable with absorption-based radiography. To monitor the morphological changes that the alveoli network undergoes in the progression of these diseases, we propose using the dark-field signal, which is related to small-angle scattering in the sample. Combined with the absorption-based image, the dark-field signal enables better discrimination between healthy and emphysematous lung tissue in a mouse model. All measurements have been performed at 36 keV using a monochromatic laser-driven miniature synchrotron X-ray source (Compact Light Source). In this paper we present grating-based dark-field images of emphysematous vs. healthy lung tissue, where the strong dependence of the dark-field signal on mean alveolar size leads to improved diagnosis of emphysema in lung radiographs. PMID:23074250

  7. The penta-prism LTP: A long-trace-profiler with stationary optical head and moving penta prism (abstract)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Qian, S.; Jark, W.; Takacs, P.Z.

    1995-02-01

    Metrology requirements for optical components for third generation synchrotron sources are taxing the state-of-the-art in manufacturing technology. We have investigated a number of effect sources in a commercial figure measurement instrument, the Long Trace Profiler II (LTP II), and have demonstrated that, with some simple modifications, we can significantly reduce the effect of error sources and improve the accuracy and reliability of the measurement. By keeping the optical head stationary and moving a penta prism along the translation stage, the stability of the optical system is greatly improved, and the remaining error signals can be corrected by a simple referencemore » beam subtraction. We illustrate the performance of the modified system by investigating the distortion produced by gravity on a typical synchrotron mirror and demonstrate the repeatability of the instrument despite relaxed tolerances on the translation stage.« less

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    This report contains viewgraphs on the following topics. The advanced light source U8 undulator beamline, 20--300 eV; gas-phase actinide studies with synchrotron radiation; atomic structure calculations for heavy atoms; flux growth of single crystal uranium intermetallics: Extension to transuranics; x-ray absorption near-edge structure studies of actinide compounds; surface as a new stage for studying actinides: Theoretical study of the surface electronic structure of uranium; magnetic x-ray scattering experiments at resonant energies; beamline instruments for radioactive materials; the search for x-ray absorption magnetic circular dichroism in actinide materials: preliminary experiments using UFe[sub 2] and U-S; the laser plasma laboratory light source:more » a source of preliminary transuranic data; electron spectroscopy of heavy fermion actinide materials; study of thin layers of actinides. Present status and future use of synchrotron radiation; electronic structure and correlated-electron theory for actinide materials; and heavy fermion and kondo phenomena in actinide materials.« less

  9. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    This report contains viewgraphs on the following topics. The advanced light source U8 undulator beamline, 20--300 eV; gas-phase actinide studies with synchrotron radiation; atomic structure calculations for heavy atoms; flux growth of single crystal uranium intermetallics: Extension to transuranics; x-ray absorption near-edge structure studies of actinide compounds; surface as a new stage for studying actinides: Theoretical study of the surface electronic structure of uranium; magnetic x-ray scattering experiments at resonant energies; beamline instruments for radioactive materials; the search for x-ray absorption magnetic circular dichroism in actinide materials: preliminary experiments using UFe{sub 2} and U-S; the laser plasma laboratory light source:more » a source of preliminary transuranic data; electron spectroscopy of heavy fermion actinide materials; study of thin layers of actinides. Present status and future use of synchrotron radiation; electronic structure and correlated-electron theory for actinide materials; and heavy fermion and kondo phenomena in actinide materials.« less

  10. X-ray metrology of an array of active edge pixel sensors for use at synchrotron light sources

    NASA Astrophysics Data System (ADS)

    Plackett, R.; Arndt, K.; Bortoletto, D.; Horswell, I.; Lockwood, G.; Shipsey, I.; Tartoni, N.; Williams, S.

    2018-01-01

    We report on the production and testing of an array of active edge silicon sensors as a prototype of a large array. Four Medipix3RX.1 chips were bump bonded to four single chip sized Advacam active edge n-on-n sensors. These detectors were then mounted into a 2 by 2 array and tested on B16 at Diamond Light Source with an x-ray beam spot of 2um. The results from these tests, compared with optical metrology demonstrate that this type of sensor is sensitive to the physical edge of the silicon, with only a modest loss of efficiency in the final two rows of pixels. We present the efficiency maps recorded with the microfocus beam and a sample powder diffraction measurement. These results give confidence that this sensor technology can be used effectively in larger arrays of detectors at synchrotron light sources.

  11. A compact radiation source for digital subtractive angiography

    NASA Astrophysics Data System (ADS)

    Wiedemann, H.; Baltay, M.; Carr, R.; Hernandez, M.; Lavender, W.

    1994-08-01

    Beam requirements for 33 keV radiation used in digital subtraction angiography have been established through extended experimentation first at Stanford and later at the National Synchrotron Light Source in Brookhaven. So far research and development of this medical procedure to image coronary blood vessels have been undertaken on large high energy electron storage rings. With progress in this diagnostic procedure, it is interesting to look for an optimum concept for providing a 33 keV radiation source which would fit into the environment of a hospital. A variety of competing effects and technologies to produce 33 keV radiation are available, but none of these processes provides the combination of sufficient photon flux and monochromaticity except for synchrotron radiation from an electron storage ring. The conceptual design of a compact storage ring optimized to fit into a hospital environment and producing sufficient 33 keV radiation for digital subtraction radiography will be discussed.

  12. Status of NSLS-II Storage Ring Vacuum Systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Doom,L.; Hseuh,H.; Ferreira, M.

    2009-05-04

    National Synchrotron Light Source II (NSLS-II), being constructed at Brookhaven National Laboratory, is a 3-GeV, high-flux and high- brightness synchrotron radiation facility with a nominal current of 500 mA. The storage ring vacuum system will have extruded aluminium chambers with ante-chamber for photon fans and distributed NEG strip pumping. Discrete photon absorbers will be used to intercept the un-used bending magnet radiation. In-situ bakeout will be implemented to achieve fast conditioning during initial commissioning and after interventions.

  13. Morphology of methane hydrate host sediments

    USGS Publications Warehouse

    Jones, K.W.; Feng, H.; Tomov, S.; Winters, W.J.; Eaton, M.; Mahajan, D.

    2005-01-01

    The morphological features including porosity and grains of methane hydrate host sediments were investigated using synchrotron computed microtomography (CMT) technique. The sediment sample was obtained during Ocean Drilling Program Leg 164 on the Blake Ridge at water depth of 2278.5 m. The CMT experiment was performed at the Brookhaven National Synchrotron Light Source facility. The analysis gave ample porosity, specific surface area, mean particle size, and tortuosity. The method was found to be highly effective for the study of methane hydrate host sediments.

  14. Preliminary synchrotron analysis of lead in hair from a lead smelter worker

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Martin, R.R.; Kempson, I.M.; Naftel, S.J.

    2008-06-09

    Synchrotron X-ray fluorescence has been used to study the distribution of lead in a hair sample collected from a lead smelter worker. A mathematical model was used to imitate the transverse scan signal based on the analysis volume and concentration profiles. The results suggest that the Pb originates both from ingestion and environmental exposure, however direct deposition from the environment is the more important source of hair lead. The model could apply equally to any other analysis involving a thin cylindrical sample.

  15. Apparatus and method for compensating for electron beam emittance in synchronizing light sources

    DOEpatents

    Neil, George R.

    1996-01-01

    A focused optical beam is used to change the path length of the core electrons in electron light sources thereby boosting their efficiency of conversion of electron beam energy to light. Both coherent light in the free electron laser and incoherent light in the synchrotron is boosted by this technique. By changing the path length of the core electrons by the proper amount, the core electrons are caused to stay in phase with the electrons in the outer distribution of the electron beam. This increases the fraction of the electron beam energy that is converted to light thereby improving the efficiency of conversion of energy to light and therefore boosting the power output of the free electron laser and synchrotron.

  16. Apparatus and method for compensating for electron beam emittance in synchronizing light sources

    DOEpatents

    Neil, G.R.

    1996-07-30

    A focused optical beam is used to change the path length of the core electrons in electron light sources thereby boosting their efficiency of conversion of electron beam energy to light. Both coherent light in the free electron laser and incoherent light in the synchrotron is boosted by this technique. By changing the path length of the core electrons by the proper amount, the core electrons are caused to stay in phase with the electrons in the outer distribution of the electron beam. This increases the fraction of the electron beam energy that is converted to light thereby improving the efficiency of conversion of energy to light and therefore boosting the power output of the free electron laser and synchrotron. 4 figs.

  17. Nuclear resonance reflectivity from a [57Fe/Cr]30 multilayer with the Synchrotron Mössbauer Source.

    PubMed

    Andreeva, Marina A; Baulin, Roman A; Chumakov, Aleksandr I; Rüffer, Rudolf; Smirnov, Gennadii V; Babanov, Yurii A; Devyaterikov, Denis I; Milyaev, Mikhail A; Ponomarev, Dmitrii A; Romashev, Lazar N; Ustinov, Vladimir V

    2018-03-01

    Mössbauer reflectivity spectra and nuclear resonance reflectivity (NRR) curves have been measured using the Synchrotron Mössbauer Source (SMS) for a [ 57 Fe/Cr] 30 periodic multilayer, characterized by the antiferromagnetic interlayer coupling between adjacent 57 Fe layers. Specific features of the Mössbauer reflectivity spectra measured with π-polarized radiation of the SMS near the critical angle and at the `magnetic' maximum on the NRR curve are analyzed. The variation of the ratio of lines in the Mössbauer reflectivity spectra and the change of the intensity of the `magnetic' maximum under an applied external field has been used to reveal the transformation of the magnetic alignment in the investigated multilayer.

  18. Operation of Negative Ion Sources at the Cooler Synchrotron COSY/Juelich

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gebel, R.; Felden, O.; Maier, R.

    2011-09-26

    The Institute for Nuclear Physics at the Forschungszentrum Juelich is dedicated to fundamental research in the field of hadron, particle and nuclear physics. Main activities are the development of the High Energy Storage Ring for the Facility for Antiproton and Ion Research at Darmstadt and the operation and improvement of the cooler synchrotron COSY at Juelich. The injector, a cyclotron with polarized and unpolarized H{sup -} and D{sup -} sources, has exceeded 7000 hours availability per year, averaged over the last decade. Work in progress is the investigation of production, extraction and transport of the low energy 4.5 keV/u ionmore » beams. A brief overview of the activities is presented.« less

  19. The Tapered Hybrid Undulator (THUNDER) of the visible free-electron laser oscillator experiment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Robinson, K.E.; Quimby, D.C.; Slater, J.M.

    A 5 m tapered hybrid undulator (THUNDER) has been designed and built as part of the Boeing Aerospace Company and Spectra Technology, Inc. visible free-electron laser (FEL) oscillator experiment. The performance goals required of an undulator for a visible oscillator with large extraction are ambitious. They require the establishment of stringent magnetic field quality tolerances which impact design and fabrication techniques. The performance goals of THUNDER are presented. The tolerances resulting from the FEL interaction are contrasted and compared to those of a synchrotron radiation source. The design, fabrication, and field measurements are discussed. The performance of THUNDER serves asmore » a benchmark for future wiggler/undulator design for advanced FEL's and synchrotron radiation sources.« less

  20. Environmental Remediation Science at Beamline X26A at the National Synchrotron Light Source- Final Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bertsch, Paul

    2013-11-07

    The goal of this project was to provide support for an advanced X-ray microspectroscopy facility at the National Synchrotron Light Source, Brookhaven National Laboratory. This facility is operated by the University of Chicago and the University of Kentucky. The facility is available to researchers at both institutions as well as researchers around the globe through the general user program. This facility was successfully supported during the project period. It provided access to advanced X-ray microanalysis techniques which lead to fundamental advances in understanding the behavior of contaminants and geochemistry that is applicable to environmental remediation of DOE legacy sites asmore » well as contaminated sites around the United States and beyond.« less

  1. Low emittance lattice for the storage ring of the Turkish Light Source Facility TURKAY

    NASA Astrophysics Data System (ADS)

    Nergiz, Z.; Aksoy, A.

    2015-06-01

    The TAC (Turkish Accelerator Center) project aims to build an accelerator center in Turkey. The first stage of the project is to construct an Infra-Red Free Electron Laser (IR-FEL) facility. The second stage is to build a synchrotron radiation facility named TURKAY, which is a third generation synchrotron radiation light source that aims to achieve a high brilliance photon beam from a low emittance electron beam at 3 GeV. The electron beam parameters are highly dependent on the magnetic lattice of the storage ring. In this paper a low emittance storage ring for TURKAY is proposed and the beam dynamic properties of the magnetic lattice are investigated. Supported by Turkish Republic Ministry of Development (DPT2006K120470)

  2. The mm-wave compact component of an AGN

    NASA Astrophysics Data System (ADS)

    Behar, Ehud; Vogel, Stuart; Baldi, Ranieri D.; Smith, Krista L.; Mushotzky, Richard F.

    2018-07-01

    mm-wave emission from active galactic nuclei (AGNs) may hold the key to understanding the physical origin of their radio cores. The correlation between radio/mm and X-ray luminosity may suggest a similar physical origin of the two sources. Since synchrotron self-absorption decreases with frequency, mm-waves probe smaller length-scales than cm-waves. We report on 100 GHz (3 mm) observations with the Combined Array for Research in Millimeter-wave Astronomy of 26 AGNs selected from the hard X-ray Swift/Burst Alert Telescope survey. 20/26 targets were detected at 100 GHz down to the 1 mJy (3σ) sensitivity, which corresponds to optically thick synchrotron source sizes of 10-4-10-3 pc. Most sources show a 100 GHz flux excess with respect to the spectral slope extrapolated from low frequencies. This mm spectral component likely originates from smaller scales than the few-GHz emission. The measured mm sources lie roughly around the Lmm (100 GHz) ˜10-4LX (2-10 keV) relation, similar to a few previously published X-ray selected sources, and hinting perhaps at a common coronal origin.

  3. The mm-wave compact component of AGN

    NASA Astrophysics Data System (ADS)

    Behar, Ehud; Vogel, Stuart; Baldi, Ranieri D.; Smith, Krista L.; Mushotzky, Richard F.

    2018-05-01

    mm-wave emission from Active Galactic Nuclei (AGN) may hold the key to understanding the physical origin of their radio cores. The correlation between radio/mm and X-ray luminosity may suggest a similar physical origin of the two sources. Since synchrotron self absorption decreases with frequency, mm-waves probe smaller length scales than cm-waves. We report on 100 GHz (3 mm) observations with CARMA of 26 AGNs selected from the hard X-ray Swift/BAT survey. 20/26 targets were detected at 100 GHz down to the 1 mJy (3σ) sensitivity, which corresponds to optically thick synchrotron source sizes of 10-4 - 10-3 pc. Most sources show a 100 GHz flux excess with respect to the spectral slope extrapolated from low frequencies. This mm spectral component likely originates from smaller scales than the few-GHz emission. The measured mm sources lie roughly around the Lmm (100 GHz) ˜10-4LX (2-10 keV) relation, similar to a few previously published X-ray selected sources, and hinting perhaps at a common coronal origin.

  4. Improving the apo-state detergent stability of NTS1 with CHESS for pharmacological and structural studies.

    PubMed

    Scott, Daniel J; Kummer, Lutz; Egloff, Pascal; Bathgate, Ross A D; Plückthun, Andreas

    2014-11-01

    The largest single class of drug targets is the G protein-coupled receptor (GPCR) family. Modern high-throughput methods for drug discovery require working with pure protein, but this has been a challenge for GPCRs, and thus the success of screening campaigns targeting soluble, catalytic protein domains has not yet been realized for GPCRs. Therefore, most GPCR drug screening has been cell-based, whereas the strategy of choice for drug discovery against soluble proteins is HTS using purified proteins coupled to structure-based drug design. While recent developments are increasing the chances of obtaining GPCR crystal structures, the feasibility of screening directly against purified GPCRs in the unbound state (apo-state) remains low. GPCRs exhibit low stability in detergent micelles, especially in the apo-state, over the time periods required for performing large screens. Recent methods for generating detergent-stable GPCRs, however, offer the potential for researchers to manipulate GPCRs almost like soluble enzymes, opening up new avenues for drug discovery. Here we apply cellular high-throughput encapsulation, solubilization and screening (CHESS) to the neurotensin receptor 1 (NTS1) to generate a variant that is stable in the apo-state when solubilized in detergents. This high stability facilitated the crystal structure determination of this receptor and also allowed us to probe the pharmacology of detergent-solubilized, apo-state NTS1 using robotic ligand binding assays. NTS1 is a target for the development of novel antipsychotics, and thus CHESS-stabilized receptors represent exciting tools for drug discovery. Copyright © 2014 Elsevier B.V. All rights reserved.

  5. Automatic Calibration of Stereo-Cameras Using Ordinary Chess-Board Patterns

    NASA Astrophysics Data System (ADS)

    Prokos, A.; Kalisperakis, I.; Petsa, E.; Karras, G.

    2012-07-01

    Automation of camera calibration is facilitated by recording coded 2D patterns. Our toolbox for automatic camera calibration using images of simple chess-board patterns is freely available on the Internet. But it is unsuitable for stereo-cameras whose calibration implies recovering camera geometry and their true-to-scale relative orientation. In contrast to all reported methods requiring additional specific coding to establish an object space coordinate system, a toolbox for automatic stereo-camera calibration relying on ordinary chess-board patterns is presented here. First, the camera calibration algorithm is applied to all image pairs of the pattern to extract nodes of known spacing, order them in rows and columns, and estimate two independent camera parameter sets. The actual node correspondences on stereo-pairs remain unknown. Image pairs of a textured 3D scene are exploited for finding the fundamental matrix of the stereo-camera by applying RANSAC to point matches established with the SIFT algorithm. A node is then selected near the centre of the left image; its match on the right image is assumed as the node closest to the corresponding epipolar line. This yields matches for all nodes (since these have already been ordered), which should also satisfy the 2D epipolar geometry. Measures for avoiding mismatching are taken. With automatically estimated initial orientation values, a bundle adjustment is performed constraining all pairs on a common (scaled) relative orientation. Ambiguities regarding the actual exterior orientations of the stereo-camera with respect to the pattern are irrelevant. Results from this automatic method show typical precisions not above 1/4 pixels for 640×480 web cameras.

  6. Focused X-ray source

    DOEpatents

    Piestrup, Melvin A.; Boyers, David G.; Pincus, Cary I.; Maccagno, Pierre

    1990-01-01

    An intense, relatively inexpensive X-ray source (as compared to a synchrotron emitter) for technological, scientific, and spectroscopic purposes. A conical radiation pattern produced by a single foil or stack of foils is focused by optics to increase the intensity of the radiation at a distance from the conical radiator.

  7. Studies of LSO:Tb radio-luminescence properties using white beam hard X-ray synchrotron irradiation

    NASA Astrophysics Data System (ADS)

    Cecilia, A.; Rack, A.; Pelliccia, D.; Douissard, P.-A.; Martin, T.; Couchaud, M.; Dupré, K.; Baumbach, T.

    A radio-luminescence set-up was installed at the synchrotron light source ANKA to characterise scintillators under the high X-ray photon flux density of white beam synchrotron radiation. The system allows for investigating the radio-luminescence spectrum of the material under study as well as analysing in situ changes of its scintillation behaviour (e.g. under heat load and/or intensive ionising radiation). In this work we applied the radio-luminescence set-up for investigating the radiation damage effects on the luminescence properties of a new kind of thin single crystal scintillator for high resolution X-ray imaging based on a layer of modified Lu2SiO5 grown by liquid phase epitaxy on a dedicated substrate within the framework of an EC project (SCINTAX).

  8. Synchrotron X-ray fluorescence analyses of stratospheric cosmic dust - New results for chondritic and low-nickel particles

    NASA Technical Reports Server (NTRS)

    Flynn, G. J.; Sutton, S. R.

    1990-01-01

    Trace element abundance determinations were performed using synchrotron X-ray fluorescence on nine particles collected from the stratosphere and classified as cosmic. Improvements to the Synchrotron Light Source allowed the detection of all elements between Cr and Mo, with the exceptions of Co and As, in our largest particle. The minor and trace element abundance patterns of three Ni-depleted particles were remarkably similar to those of extraterrestrial igneous rocks. Fe/Ni and Fe/Mn ratios suggest that one of these may be of lunar origin. All nine particles exhibited an enrichment in Br, ranging from 1.3 to 38 times the C1 concentration. Br concentrations were uncorrelated with particle size, as would be expected for a surface correlated component acquires from the stratosphere.

  9. Understanding the Differences in Molecular Conformation of Carbohydrate and Protein in Endosperm Tissues of Grains with Different Biodegradation Kinetics Using Advanced Synchrotron Technology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yu, P.; Block, H; Doiron, K

    Conventional 'wet' chemical analyses rely heavily on the use of harsh chemicals and derivatization, thereby altering native seed structures leaving them unable to detect any original inherent structures within an intact tissue sample. A synchrotron is a giant particle accelerator that turns electrons into light (million times brighter than sunlight) which can be used to study the structure of materials at the molecular level. Synchrotron radiation-based Fourier transform IR microspectroscopy (SR-FTIRM) has been developed as a rapid, direct, non-destructive and bioanalytical technique. This technique, taking advantage of the brightness of synchrotron light and a small effective source size, is capablemore » of exploring the molecular chemistry within the microstructures of a biological tissue without the destruction of inherent structures at ultraspatial resolutions within cellular dimensions. This is in contrast to traditional 'wet' chemical methods, which, during processing for analysis, often result in the destruction of the intrinsic structures of feeds. To date there has been very little application of this technique to the study of plant seed tissue in relation to nutrient utilization. The objective of this study was to use novel synchrotron radiation-based technology (SR-FTIRM) to identify the differences in the molecular chemistry and conformation of carbohydrate and protein in various plant seed endosperms within intact tissues at cellular and subcellular level from grains with different biodegradation kinetics. Barley grain (cv. Harrington) with a high rate (31.3%/h) and extent (78%), corn grain (cv. Pioneer) with a low rate (9.6%/h) and extent of (57%), and wheat grain (cv. AC Barrie) with an intermediate rate (23%/h) and extent (72%) of ruminal DM degradation were selected for evaluation. SR-FTIRM evaluations were performed at the National Synchrotron Light Source at the Brookhaven National Laboratory (Brookhaven, NY). These results suggest that SR-FTIRM plus the multivariate analyses can be used to identify spectral features associated with the molecular structure of endosperm from grains with different biodegradation kinetics, especially in relation to protein structure. The Novel synchrotron radiation-based bioanalytical technique provides a new approach for plant seed structural molecular studies at ultraspatial resolution and within intact tissue in relation to nutrient availability.« less

  10. A sparsity-based iterative algorithm for reconstruction of micro-CT images from highly undersampled projection datasets obtained with a synchrotron X-ray source

    NASA Astrophysics Data System (ADS)

    Melli, S. Ali; Wahid, Khan A.; Babyn, Paul; Cooper, David M. L.; Gopi, Varun P.

    2016-12-01

    Synchrotron X-ray Micro Computed Tomography (Micro-CT) is an imaging technique which is increasingly used for non-invasive in vivo preclinical imaging. However, it often requires a large number of projections from many different angles to reconstruct high-quality images leading to significantly high radiation doses and long scan times. To utilize this imaging technique further for in vivo imaging, we need to design reconstruction algorithms that reduce the radiation dose and scan time without reduction of reconstructed image quality. This research is focused on using a combination of gradient-based Douglas-Rachford splitting and discrete wavelet packet shrinkage image denoising methods to design an algorithm for reconstruction of large-scale reduced-view synchrotron Micro-CT images with acceptable quality metrics. These quality metrics are computed by comparing the reconstructed images with a high-dose reference image reconstructed from 1800 equally spaced projections spanning 180°. Visual and quantitative-based performance assessment of a synthetic head phantom and a femoral cortical bone sample imaged in the biomedical imaging and therapy bending magnet beamline at the Canadian Light Source demonstrates that the proposed algorithm is superior to the existing reconstruction algorithms. Using the proposed reconstruction algorithm to reduce the number of projections in synchrotron Micro-CT is an effective way to reduce the overall radiation dose and scan time which improves in vivo imaging protocols.

  11. SESAME-A 3rd Generation Synchrotron Light Source for the Middle East

    NASA Astrophysics Data System (ADS)

    Winick, Herman

    2010-02-01

    Developed under the auspices of UNESCO and modeled on CERN, SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East) is an international research center in construction in Jordan. It will enable world class research by scientists from the region, reversing the brain drain. It will also build bridges between diverse societies, contributing to a culture of peace through international cooperation in science. The centerpiece is a synchrotron light source originating from BESSY I, a gift by Germany. The upgraded machine, a 2.5 GeV 3rd Generation Light Source (133m circumference, 26nm-rad emittance and 12 places for insertion devices), will provide light from infra-red to hard X-rays, offering excellent opportunities to train local scientists and attract those working abroad to return. The SESAME Council meets twice each year and presently has nine Members (Bahrain, Cyprus, Egypt, Iran, Israel, Jordan, Pakistan, Palestinian Authority, Turkey). Members have responsibility for the project and provide the annual operations budget (1.5M US dollars in 2009, expected to rise to about 5M when operation starts in 2012-13). Jordan provided the site, building, and infrastructure. A staff of 20 is installing the 0.8 GeV BESSY I injection system. The facility will have the capacity to serve 30 or more experiments operating simultaneously. See www.sesame.org.jo )

  12. Focused X-ray source

    DOEpatents

    Piestrup, M.A.; Boyers, D.G.; Pincus, C.I.; Maccagno, P.

    1990-08-21

    Disclosed is an intense, relatively inexpensive X-ray source (as compared to a synchrotron emitter) for technological, scientific, and spectroscopic purposes. A conical radiation pattern produced by a single foil or stack of foils is focused by optics to increase the intensity of the radiation at a distance from the conical radiator. 8 figs.

  13. PTB’s radiometric scales for UV and VUV source calibration based on synchrotron radiation

    NASA Astrophysics Data System (ADS)

    Klein, Roman; Kroth, Simone; Paustian, Wolfgang; Richter, Mathias; Thornagel, Reiner

    2018-06-01

    The radiant intensity of synchrotron radiation can be accurately calculated with classical electrodynamics. This primary realization of the spectral radiant intensity has been used by PTB at several electron storage rings which have been optimized to be operated as primary source standards for the calibration of transfer sources in the spectral range of UV and VUV for almost 30 years. The transfer sources are compared to the primary source standard by means of suitable wavelength-dispersive transfer stations. The spectral range covered by deuterium lamps, which represent transfer sources that are easy to handle, is of particular relevance in practice. Here, we report on developments in the realization and preservation of the radiometric scales for spectral radiant intensity and spectral radiance in the wavelength region from 116 nm to 400 nm, based on a set of deuterium reference lamps, over the last few decades. An inside view and recommendations on the operation of the D2 lamps used for the realization of the radiometric scale are presented. The data has been recently compiled to illustrate the chronological behaviour at various wavelengths. Moreover, an overview of the internal and external validation measurements and intercomparisons is given.

  14. X-ray grating interferometer for materials-science imaging at a low-coherent wiggler source

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Herzen, Julia; Physics Department and Institute for Medical Engineering, Technische Universitaet Muenchen, 85748 Garching; Donath, Tilman

    2011-11-15

    X-ray phase-contrast radiography and tomography enable to increase contrast for weakly absorbing materials. Recently, x-ray grating interferometers were developed that extend the possibility of phase-contrast imaging from highly brilliant radiation sources like third-generation synchrotron sources to non-coherent conventional x-ray tube sources. Here, we present the first installation of a three grating x-ray interferometer at a low-coherence wiggler source at the beamline W2 (HARWI II) operated by the Helmholtz-Zentrum Geesthacht at the second-generation synchrotron storage ring DORIS (DESY, Hamburg, Germany). Using this type of the wiggler insertion device with a millimeter-sized source allows monochromatic phase-contrast imaging of centimeter sized objects withmore » high photon flux. Thus, biological and materials-science imaging applications can highly profit from this imaging modality. The specially designed grating interferometer currently works in the photon energy range from 22 to 30 keV, and the range will be increased by using adapted x-ray optical gratings. Our results of an energy-dependent visibility measurement in comparison to corresponding simulations demonstrate the performance of the new setup.« less

  15. Simultaneous Multiwavelength Observations of the Blazar 1ES 1959+650 at a Low TeV Flux

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tagliaferri, G.; Ghisellini, G.; Foschini, L.

    We present the results from a multiwavelength campaign on the TeV blazar 1ES 1959+650, performed in 2006 May. Data from the optical, UV, soft- and hard-X-ray, and very high energy (VHE) gamma-ray (E > 100 GeV) bands were obtained with the Suzaku and Swift satellites, the MAGIC telescope, and other ground-based facilities. The source spectral energy distribution (SED), derived from Suzaku and MAGIC observations at the end of 2006 May, shows the usual double hump shape, with the synchrotron peak at a higher flux level than the Compton peak. With respect to historical values, during our campaign the source exhibitedmore » a relatively high state in X-rays and optical, while in the VHE band it was at one of the lowest level so far recorded. We also monitored the source for flux spectral variability on a time window of 10 days in the optical-UV and X-ray bands and 7 days in the VHE band. The source varies more in the X-ray than in the optical band, with the 2-10 keV X-ray flux varying by a factor of {approx}2. The synchrotron peak is located in the X-ray band and moves to higher energies as the source gets brighter, with the X-ray fluxes above it varying more rapidly than the X-ray fluxes at lower energies. The variability behavior observed in the X-ray band cannot be produced by emitting regions varying independently and suggests instead some sort of 'standing shock' scenario. The overall SED is well represented by a homogeneous one-zone synchrotron inverse Compton emission model, from which we derive physical parameters that are typical of high-energy peaked blazars.« less

  16. Third user workshop on high-power lasers at the Linac Coherent Light Source

    DOE PAGES

    Bolme, Cynthia Anne; Glenzer, Sigfried; Fry, Alan

    2016-03-24

    On October 5–6, 2015, the third international user workshop focusing on high-power lasers at the Linac Coherent Light Source (LCLS) was held in Menlo Park, CA, USA [1 R. Falcone, S. Glenzer, and S. Hau-Riege, Synchrotron Radiation News 27(2), 56–58 (2014)., 2 P. Heimann and S. Glenzer, Synchrotron Radiation News 28(3), 54–56 (2015).]. Here, the workshop was co-organized by Los Alamos National Laboratory and SLAC National Accelerator Laboratory. More than 110 scientists attended from North America, Europe, and Asia to discuss high-energy-density (HED) science that is enabled by the unique combination of high-power lasers with the LCLS X-rays at themore » LCLS-Matter in Extreme Conditions (MEC) endstation.« less

  17. Crystal regularity with high-resolution synchrotron X-radiation diffraction imaging

    NASA Technical Reports Server (NTRS)

    Steiner, Bruce; Dobbyn, Ronald C.

    1991-01-01

    New, high-resolution sources of X-radiation such as monochromatic synchrotron radiation beams with subarcsec divergence allow observation of regularities in a range of crystals with sufficient clarity for comprehensive analyses, whose results can deepen understanding of the nature of various crystal irregularities, their sources, and their effects on device performance. An account is presented of the results thus achievable with irregularities encountered in lattice orientation and strain, grain and subgrain boundaries, dislocations, domain boundaries, additional phases, and surface scratches. Significant achievements to date encompass the observation of critical anomalies in lead tin telluride, the reconciliation of disparate observations of GaAs, the determination of the performance effects of irregularities in mercuric iodide, and the characterization of the origins of crystal growth in bismuth silicon oxide.

  18. Evolution of synchrotron-radiation-based Mössbauer absorption spectroscopy for various isotopes

    NASA Astrophysics Data System (ADS)

    Seto, Makoto; Masuda, Ryo; Kobayashi, Yasuhiro; Kitao, Shinji; Kurokuzu, Masayuki; Saito, Makina; Hosokawa, Shuuich; Ishibashi, Hiroki; Mitsui, Takaya; Yoda, Yoshitaka; Mibu, Ko

    2017-11-01

    Synchrotron-radiation-based Mössbauer spectroscopy that yields absorption type Mössbauer spectra has been applied to various isotopes. This method enables the advanced measurement by using the excellent features of synchrotron radiation, such as Mössbauer spectroscopic measurement under high-pressures. Furthermore, energy selectivity of synchrotron radiation allows us to measure 40K Mössbauer spectra, of which observation is impossible by using ordinary radioactive sources because the first excited state of 40K is not populated by any radioactive parent nuclides. Moreover, this method has flexibility of the experimental setup that the measured sample can be used as a transmitter or a scatterer, depending on the sample conditions. To enhance the measurement efficiency of the spectroscopy, we developed a detection system in which a windowless avalanche photodiode (APD) detector is combined with a vacuum cryostat to detect internal conversion electrons adding to X-rays accompanied by nuclear de-excitation. In particular, by selecting the emission from the scatterer sample, depth selective synchrotron-radiation-based Mössbauer spectroscopy is possible. Furthermore, limitation of the time window in the delayed components enables us to obtain narrow linewidth in Mössbauer spectra. Measurement system that records velocity dependent time spectra and energy information simultaneously realizes the depth selective and narrow linewidth measurement.

  19. Probing the self-assembled nanostructures of functional polymers with synchrotron grazing incidence X-ray scattering.

    PubMed

    Ree, Moonhor

    2014-05-01

    For advanced functional polymers such as biopolymers, biomimic polymers, brush polymers, star polymers, dendritic polymers, and block copolymers, information about their surface structures, morphologies, and atomic structures is essential for understanding their properties and investigating their potential applications. Grazing incidence X-ray scattering (GIXS) is established for the last 15 years as the most powerful, versatile, and nondestructive tool for determining these structural details when performed with the aid of an advanced third-generation synchrotron radiation source with high flux, high energy resolution, energy tunability, and small beam size. One particular merit of this technique is that GIXS data can be obtained facilely for material specimens of any size, type, or shape. However, GIXS data analysis requires an understanding of GIXS theory and of refraction and reflection effects, and for any given material specimen, the best methods for extracting the form factor and the structure factor from the data need to be established. GIXS theory is reviewed here from the perspective of practical GIXS measurements and quantitative data analysis. In addition, schemes are discussed for the detailed analysis of GIXS data for the various self-assembled nanostructures of functional homopolymers, brush, star, and dendritic polymers, and block copolymers. Moreover, enhancements to the GIXS technique are discussed that can significantly improve its structure analysis by using the new synchrotron radiation sources such as third-generation X-ray sources with picosecond pulses and partial coherence and fourth-generation X-ray laser sources with femtosecond pulses and full coherence. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. Application of Synchrotron Microprobe Methods to Solid-Phase Speciation of Metals and Metalloids in House Dust

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    S Walker; H Jamieson; P Rasmussen

    2011-12-31

    Determination of the source and form of metals in house dust is important to those working to understand human and particularly childhood exposure to metals in residential environments. We report the development of a synchrotron microprobe technique for characterization of multiple metal hosts in house dust. We have applied X-ray fluorescence for chemical characterization and X-ray diffraction for crystal structure identification using microfocused synchrotron X-rays at a less than 10 {micro}m spot size. The technique has been evaluated by application to archived house dust samples containing elevated concentrations of Pb, Zn, and Ba in bedroom dust, and Pb and Asmore » in living room dust. The technique was also applied to a sample of soil from the corresponding garden to identify linkages between indoor and outdoor sources of metals. Paint pigments including white lead (hydrocerussite) and lithopone (wurtzite and barite) are the primary source of Pb, Zn, and Ba in bedroom dust, probably related to renovation activity in the home at the time of sampling. The much lower Pb content in the living room dust shows a relationship to the exterior soil and no specific evidence of Pb and Zn from the bedroom paint pigments. The technique was also successful at confirming the presence of chromated copper arsenate treated wood as a source of As in the living room dust. The results of the study have confirmed the utility of this approach in identifying specific metal forms within the dust.« less

  1. Putting tools in the toolbox: Development of a free, open-source toolbox for quantitative image analysis of porous media.

    NASA Astrophysics Data System (ADS)

    Iltis, G.; Caswell, T. A.; Dill, E.; Wilkins, S.; Lee, W. K.

    2014-12-01

    X-ray tomographic imaging of porous media has proven to be a valuable tool for investigating and characterizing the physical structure and state of both natural and synthetic porous materials, including glass bead packs, ceramics, soil and rock. Given that most synchrotron facilities have user programs which grant academic researchers access to facilities and x-ray imaging equipment free of charge, a key limitation or hindrance for small research groups interested in conducting x-ray imaging experiments is the financial cost associated with post-experiment data analysis. While the cost of high performance computing hardware continues to decrease, expenses associated with licensing commercial software packages for quantitative image analysis continue to increase, with current prices being as high as $24,000 USD, for a single user license. As construction of the Nation's newest synchrotron accelerator nears completion, a significant effort is being made here at the National Synchrotron Light Source II (NSLS-II), Brookhaven National Laboratory (BNL), to provide an open-source, experiment-to-publication toolbox that reduces the financial and technical 'activation energy' required for performing sophisticated quantitative analysis of multidimensional porous media data sets, collected using cutting-edge x-ray imaging techniques. Implementation focuses on leveraging existing open-source projects and developing additional tools for quantitative analysis. We will present an overview of the software suite that is in development here at BNL including major design decisions, a demonstration of several test cases illustrating currently available quantitative tools for analysis and characterization of multidimensional porous media image data sets and plans for their future development.

  2. Review of the Elementary Particles Physics in the External Electromagnetic Fields Studies at KEK

    NASA Astrophysics Data System (ADS)

    Konstantinova, O. Tanaka

    2017-03-01

    High Energy Accelerator Research Organization (KEK [1]) is a world class accelerator-based research laboratory. The field of its scientific interests spreads widely from the study of fundamental properties of matter, particle physics, nuclear physics to materials science, life science, technical researches, and industrial applications. Research outcomes from the laboratory achieved making use of high-energy particle beams and synchrotron radiation. Two synchrotron facilities of KEK, the Photon Factory (PF) ring and the Photon Factory Advanced Ring (PF-AR) are the second biggest synchrotron light source in Japan. A very wide range of the radiated light, from visible light to X-ray, is provided for a variety of materials science, biology, and life science [2]. KEK strives to work closely with national and international research institutions, promoting collaborative research activities. Advanced research and facilities provision are key factors to be at the frontier of the accelerator science. In this review I am going to discuss KEK overall accelerator-based science, and to consider light sources research and development. The state of arts of the current projects with respect to the elementary particles physics in the external electromagnetic fields is also stressed here.

  3. Toward a fourth-generation x-ray source.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Monction, D. E.

    1999-05-19

    The field of synchrotron radiation research has grown rapidly over the last 25 years due to both the push of the accelerator and magnet technology that produces the x-ray beams and the pull of the extraordinary scientific research that is possible with them. Three successive generations of synchrotrons radiation facilities have resulted in beam brilliances 11 to 12 orders of magnitude greater than the standard laboratory x-ray tube. However, greater advances can be easily imagined given the fact that x-ray beams from present-day facilities do not exhibit the coherence or time structure so familiar with the optical laser. Theoretical workmore » over the last ten years or so has pointed to the possibility of generating hard x-ray beams with laser-like characteristics. The concept is based on self-amplified spontaneous emission (SASE) in flee-electron lasers. A major facility of this type based upon a superconducting linac could produce a cost-effective facility that spans wave-lengths from the ultraviolet to the hard x-ray regime, simultaneously servicing large numbers experimenters from a wide range of disciplines. As with each past generation of synchrotrons facilities, immense new scientific opportunities would result from fourth-generation sources.« less

  4. Time-resolved experiments in the frequency domain using synchrotron radiation (invited)

    NASA Astrophysics Data System (ADS)

    De Stasio, Gelsomina; Giusti, A. M.; Parasassi, T.; Ravagnan, G.; Sapora, O.

    1992-01-01

    PLASTIQUE is the only synchrotron radiation beam line in the world that performs time-resolved fluorescence experiments in frequency domain. These experiments are extremely valuable sources of information on the structure and the dynamics of molecules. This technique measures fluorescence lifetimes with picosecond resolution in the near UV spectral range. Such accurate measurements are rendered possible by taking phase and modulation data, and by the advantages of the cross-correlation technique. A successful experiment demonstrated the radiation damage induced by low doses of radiation on rabbit blood cell membranes.

  5. VUV-soft x-ray beamline for spectroscopy and calibration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bartlett, R.J.; Trela, W.J.; Southworth, S.H.

    1986-01-01

    We describe the design and performance of the Los Alamos VUV synchrotron radiation beamline, U3C, on the VUV ring of the National Synchrotron Light Source at Brookhaven National Laboratory. The beamline uses separate function optics to collect and focus the horizontally and vertically diverging beam. The monochromator is a grazing incidence Roland circle instrument of the extended grasshopper design (ERG). A post monochromator refocusing mirror is used to focus or collimate the diverging beam from the monochromator. The beamline control and diagnostics systems are also discussed.

  6. A new XUV optical end-station to characterize compact and flexible photonic devices using synchrotron radiation

    NASA Astrophysics Data System (ADS)

    Marcelli, A.; Mazuritskiy, M. I.; Dabagov, S. B.; Hampai, D.; Lerer, A. M.; Izotova, E. A.; D'Elia, A.; Turchini, S.; Zema, N.; Zuccaro, F.; de Simone, M.; Javad Rezvani, S.; Coreno, M.

    2018-03-01

    In this contribution we present the new experimental end-station to characterize XUV diffractive optics, such as Micro Channel Plates (MCPs) and other polycapillary optics, presently under commission at the Elettra synchrotron radiation laboratory (Trieste, Italy). To show the opportunities offered by these new optical devices for 3rd and 4th generation radiation sources, in this work we present also some patterns collected at different energies of the primary XUV radiation transmitted by MCP optical devices working in the normal incidence geometry.

  7. A resolution designating October 13, 2012, as "National Chess Day".

    THOMAS, 112th Congress

    Sen. Rockefeller, John D., IV [D-WV

    2012-08-01

    Senate - 08/01/2012 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (All Actions) Tracker: This bill has the status Agreed to in SenateHere are the steps for Status of Legislation:

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chen, Jingguang; Frenkel, Anatoly; Rodriguez, Jose

    Synchrotron spectroscopies offer unique advantages over conventional techniques, including higher detection sensitivity and molecular specificity, faster detection rate, and more in-depth information regarding the structural, electronic and catalytic properties under in-situ reaction conditions. Despite these advantages, synchrotron techniques are often underutilized or unexplored by the catalysis community due to various perceived and real barriers, which will be addressed in the current proposal. Since its establishment in 2005, the Synchrotron Catalysis Consortium (SCC) has coordinated significant efforts to promote the utilization of cutting-edge catalytic research under in-situ conditions. The purpose of the current renewal proposal is aimed to provide assistance, andmore » to develop new sciences/techniques, for the catalysis community through the following concerted efforts: Coordinating the implementation of a suite of beamlines for catalysis studies at the new NSLS-II synchrotron source; Providing assistance and coordination for catalysis users at an SSRL catalysis beamline during the initial period of NSLS to NSLS II transition; Designing in-situ reactors for a variety of catalytic and electrocatalytic studies; Assisting experimental set-up and data analysis by a dedicated research scientist; Offering training courses and help sessions by the PIs and co-PIs.« less

  9. Specific chemical and structural damage to proteins produced by synchrotron radiation.

    PubMed

    Weik, M; Ravelli, R B; Kryger, G; McSweeney, S; Raves, M L; Harel, M; Gros, P; Silman, I; Kroon, J; Sussman, J L

    2000-01-18

    Radiation damage is an inherent problem in x-ray crystallography. It usually is presumed to be nonspecific and manifested as a gradual decay in the overall quality of data obtained for a given crystal as data collection proceeds. Based on third-generation synchrotron x-ray data, collected at cryogenic temperatures, we show for the enzymes Torpedo californica acetylcholinesterase and hen egg white lysozyme that synchrotron radiation also can cause highly specific damage. Disulfide bridges break, and carboxyl groups of acidic residues lose their definition. Highly exposed carboxyls, and those in the active site of both enzymes, appear particularly susceptible. The catalytic triad residue, His-440, in acetylcholinesterase, also appears to be much more sensitive to radiation damage than other histidine residues. Our findings have direct practical implications for routine x-ray data collection at high-energy synchrotron sources. Furthermore, they provide a direct approach for studying the radiation chemistry of proteins and nucleic acids at a detailed, structural level and also may yield information concerning putative "weak links" in a given biological macromolecule, which may be of structural and functional significance.

  10. Recent Advances and Applications in Synchrotron X-Ray Protein Footprinting for Protein Structure and Dynamics Elucidation.

    PubMed

    Gupta, Sayan; Feng, Jun; Chance, Mark; Ralston, Corie

    2016-01-01

    Synchrotron X-ray Footprinting is a powerful in situ hydroxyl radical labeling method for analysis of protein structure, interactions, folding and conformation change in solution. In this method, water is ionized by high flux density broad band synchrotron X-rays to produce a steady-state concentration of hydroxyl radicals, which then react with solvent accessible side-chains. The resulting stable modification products are analyzed by liquid chromatography coupled to mass spectrometry. A comparative reactivity rate between known and unknown states of a protein provides local as well as global information on structural changes, which is then used to develop structural models for protein function and dynamics. In this review we describe the XF-MS method, its unique capabilities and its recent technical advances at the Advanced Light Source. We provide a comparison of other hydroxyl radical and mass spectrometry based methods with XFMS. We also discuss some of the latest developments in its usage for studying bound water, transmembrane proteins and photosynthetic protein components, and the synergy of the method with other synchrotron based structural biology methods.

  11. UV-Visible Absorption Spectroscopy Enhanced X-ray Crystallography at Synchrotron and X-ray Free Electron Laser Sources.

    PubMed

    Cohen, Aina E; Doukov, Tzanko; Soltis, Michael S

    2016-01-01

    This review describes the use of single crystal UV-Visible Absorption micro-Spectrophotometry (UV-Vis AS) to enhance the design and execution of X-ray crystallography experiments for structural investigations of reaction intermediates of redox active and photosensitive proteins. Considerations for UV-Vis AS measurements at the synchrotron and associated instrumentation are described. UV-Vis AS is useful to verify the intermediate state of an enzyme and to monitor the progression of reactions within crystals. Radiation induced redox changes within protein crystals may be monitored to devise effective diffraction data collection strategies. An overview of the specific effects of radiation damage on macromolecular crystals is presented along with data collection strategies that minimize these effects by combining data from multiple crystals used at the synchrotron and with the X-ray free electron laser.

  12. Broadband Spectral Modeling of the Extreme Gigahertz-peaked Spectrum Radio Source PKS B0008-421

    NASA Astrophysics Data System (ADS)

    Callingham, J. R.; Gaensler, B. M.; Ekers, R. D.; Tingay, S. J.; Wayth, R. B.; Morgan, J.; Bernardi, G.; Bell, M. E.; Bhat, R.; Bowman, J. D.; Briggs, F.; Cappallo, R. J.; Deshpande, A. A.; Ewall-Wice, A.; Feng, L.; Greenhill, L. J.; Hazelton, B. J.; Hindson, L.; Hurley-Walker, N.; Jacobs, D. C.; Johnston-Hollitt, M.; Kaplan, D. L.; Kudrayvtseva, N.; Lenc, E.; Lonsdale, C. J.; McKinley, B.; McWhirter, S. R.; Mitchell, D. A.; Morales, M. F.; Morgan, E.; Oberoi, D.; Offringa, A. R.; Ord, S. M.; Pindor, B.; Prabu, T.; Procopio, P.; Riding, J.; Srivani, K. S.; Subrahmanyan, R.; Udaya Shankar, N.; Webster, R. L.; Williams, A.; Williams, C. L.

    2015-08-01

    We present broadband observations and spectral modeling of PKS B0008-421 and identify it as an extreme gigahertz-peaked spectrum (GPS) source. PKS B0008-421 is characterized by the steepest known spectral slope below the turnover, close to the theoretical limit of synchrotron self-absorption, and the smallest known spectral width of any GPS source. Spectral coverage of the source spans from 0.118 to 22 GHz, which includes data from the Murchison Widefield Array and the wide bandpass receivers on the Australia Telescope Compact Array. We have implemented a Bayesian inference model fitting routine to fit the data with internal free-free absorption (FFA), single- and double-component FFA in an external homogeneous medium, FFA in an external inhomogeneous medium, or single- and double-component synchrotron self-absorption models, all with and without a high-frequency exponential break. We find that without the inclusion of a high-frequency break these models cannot accurately fit the data, with significant deviations above and below the peak in the radio spectrum. The addition of a high-frequency break provides acceptable spectral fits for the inhomogeneous FFA and double-component synchrotron self-absorption models, with the inhomogeneous FFA model statistically favored. The requirement of a high-frequency spectral break implies that the source has ceased injecting fresh particles. Additional support for the inhomogeneous FFA model as being responsible for the turnover in the spectrum is given by the consistency between the physical parameters derived from the model fit and the implications of the exponential spectral break, such as the necessity of the source being surrounded by a dense ambient medium to maintain the peak frequency near the gigahertz region. This implies that PKS B0008-421 should display an internal H i column density greater than 1020 cm-2. The discovery of PKS B0008-421 suggests that the next generation of low radio frequency surveys could reveal a large population of GPS sources that have ceased activity, and that a portion of the ultra-steep-spectrum source population could be composed of these GPS sources in a relic phase.

  13. Direct micro-CT observation confirms the induction of embolism upon xylem cutting under tension

    USDA-ARS?s Scientific Manuscript database

    We used two different Synchrotron-based micro-CT facilities (SLS: Swiss Light Source, Villigen, Switzerland, and ALS: Advanced Light Source, Berkeley, CA USA) to test the excision artifact described by Wheeler et al. (2013). Specifically, we examined the impact of cutting xylem under tension and und...

  14. SYNCHROTRON RADIATION, FREE ELECTRON LASER, APPLICATION OF NUCLEAR TECHNOLOGY, ETC. Design of a multi-cusp ion source for proton therapy

    NASA Astrophysics Data System (ADS)

    Wu, Xiao-Bing; Huang, Tao; Ouyang, Hua-Fu; Zhang, Hua-Shun; Gong, Ke-Yun

    2010-12-01

    The permanent magnets of the discharge chamber in a multi-cusp proton source are studied and designed. The three electrode extraction system is adopted and simulated. A method to extract different amounts of current while keeping the beam emittance unchanged is proposed.

  15. Gas gun shock experiments with single-pulse x-ray phase contrast imaging and diffraction at the Advanced Photon Source

    NASA Astrophysics Data System (ADS)

    Luo, S. N.; Jensen, B. J.; Hooks, D. E.; Fezzaa, K.; Ramos, K. J.; Yeager, J. D.; Kwiatkowski, K.; Shimada, T.

    2012-07-01

    The highly transient nature of shock loading and pronounced microstructure effects on dynamic materials response call for in situ, temporally and spatially resolved, x-ray-based diagnostics. Third-generation synchrotron x-ray sources are advantageous for x-ray phase contrast imaging (PCI) and diffraction under dynamic loading, due to their high photon fluxes, high coherency, and high pulse repetition rates. The feasibility of bulk-scale gas gun shock experiments with dynamic x-ray PCI and diffraction measurements was investigated at the beamline 32ID-B of the Advanced Photon Source. The x-ray beam characteristics, experimental setup, x-ray diagnostics, and static and dynamic test results are described. We demonstrate ultrafast, multiframe, single-pulse PCI measurements with unprecedented temporal (<100 ps) and spatial (˜2 μm) resolutions for bulk-scale shock experiments, as well as single-pulse dynamic Laue diffraction. The results not only substantiate the potential of synchrotron-based experiments for addressing a variety of shock physics problems, but also allow us to identify the technical challenges related to image detection, x-ray source, and dynamic loading.

  16. Development Status of Ion Source at J-PARC Linac Test Stand

    NASA Astrophysics Data System (ADS)

    Yamazaki, S.; Takagi, A.; Ikegami, K.; Ohkoshi, K.; Ueno, A.; Koizumi, I.; Oguri, H.

    The Japan Proton Accelerator Research Complex (J-PARC) linac power upgrade program is now in progress in parallel with user operation. To realize a nominal performance of 1 MW at 3 GeV Rapid Cycling Synchrotron and 0.75 MW at the Main Ring synchrotron, we need to upgrade the peak beam current (50 mA) of the linac. For the upgrade program, we are testing a new front-end system, which comprises a cesiated RF-driven H- ion source and a new radio -frequency quadrupole linac (RFQ). The H- ion source was developed to satisfy the J-PARC upgrade requirements of an H- ion-beam current of 60 mA and a lifetime of more than 50 days. On February 6, 2014, the first 50 mA H- beams were accelerated by the RFQ during a beam test. To demonstrate the performance of the ion source before its installation in the summer of 2014, we tested the long-term stability through continuous beam operation, which included estimating the lifetime of the RF antenna and evaluating the cesium consumption.

  17. [A clinical, health, economic and satisfaction simulation model, CHESS: a tool for healthcare organization management].

    PubMed

    Meilik, Ahuva; Afek, Arnon; Rotstein, Zeev

    2009-03-01

    The management of medical organizations is based on a profound understanding of the essence of the organization, its vision and missions, as well as the methods the organization utilizes to gather and analyze information. In order to maintain a maximal function level in an ever-changing environment, all organization components must function in tandem. In a previous article the authors presented medical organizations as macro systems composed of micro systems, and discussed the challenges these organization face today. Basing optimal system management on micro medical systems allows the organizations to make maximum use of the advantages that professionalism encompasses, in a flexible micro-system environment. In this article, the authors attempt to present an interactive solution for performing assessments and management in the medical arena--the CHESS model. This solution was developed at the Sheba Medical Center. The CHESS Simulator (Clinical Health Economic and Satisfaction Simulator) was formulated to function as a clinical organizational intelligence system, whose function was to supply quantitative, analyzed data regarding activity on the clinical production floor. The system is unique in that it has a differential view of the complex medical procedures which are highly variable, and also has the capability to locate elements that are based in a common similarity. Data gathering will be based on an online system computerized medical file (EMR), which is a priority for a functioning system. This solution allows medical organization (macro-system] managers and the departments (micro system) directors to make informed decisions that will ensure that the organization's goals are achieved. This is defined as evolving from a reactive management pattern to a proactive management pattern that is mandatory in the competitive atmosphere of the 21st Century.

  18. Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation

    PubMed Central

    Conrad, Chelsie E.; Nelson, Garrett; Stander, Natasha; Zatsepin, Nadia A.; Zook, James; Zhu, Lan; Geiger, James; Chun, Eugene; Kissick, David; Hilgart, Mark C.; Ogata, Craig; Ishchenko, Andrii; Nagaratnam, Nirupa; Roy-Chowdhury, Shatabdi; Coe, Jesse; Subramanian, Ganesh; Schaffer, Alexander; Ketwala, Gihan; Venugopalan, Nagarajan; Xu, Shenglan; Corcoran, Stephen; Ferguson, Dale; Weierstall, Uwe; Spence, John C. H.; Cherezov, Vadim; Fromme, Petra; Fischetti, Robert F.; Liu, Wei

    2017-01-01

    Crystal structure determination of biological macromolecules using the novel technique of serial femtosecond crystallography (SFX) is severely limited by the scarcity of X-ray free-electron laser (XFEL) sources. However, recent and future upgrades render microfocus beamlines at synchrotron-radiation sources suitable for room-temperature serial crystallography data collection also. Owing to the longer exposure times that are needed at synchrotrons, serial data collection is termed serial millisecond crystallography (SMX). As a result, the number of SMX experiments is growing rapidly, with a dozen experiments reported so far. Here, the first high-viscosity injector-based SMX experiments carried out at a US synchrotron source, the Advanced Photon Source (APS), are reported. Microcrystals (5–20 µm) of a wide variety of proteins, including lysozyme, thaumatin, phycocyanin, the human A2A adenosine receptor (A2AAR), the soluble fragment of the membrane lipoprotein Flpp3 and proteinase K, were screened. Crystals suspended in lipidic cubic phase (LCP) or a high-molecular-weight poly(ethylene oxide) (PEO; molecular weight 8 000 000) were delivered to the beam using a high-viscosity injector. In-house data-reduction (hit-finding) software developed at APS as well as the SFX data-reduction and analysis software suites Cheetah and CrystFEL enabled efficient on-site SMX data monitoring, reduction and processing. Complete data sets were collected for A2AAR, phycocyanin, Flpp3, proteinase K and lysozyme, and the structures of A2AAR, phycocyanin, proteinase K and lysozyme were determined at 3.2, 3.1, 2.65 and 2.05 Å resolution, respectively. The data demonstrate the feasibility of serial millisecond crystallography from 5–20 µm crystals using a high-viscosity injector at APS. The resolution of the crystal structures obtained in this study was dictated by the current flux density and crystal size, but upcoming developments in beamline optics and the planned APS-U upgrade will increase the intensity by two orders of magnitude. These developments will enable structure determination from smaller and/or weakly diffracting microcrystals. PMID:28875031

  19. Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation.

    PubMed

    Martin-Garcia, Jose M; Conrad, Chelsie E; Nelson, Garrett; Stander, Natasha; Zatsepin, Nadia A; Zook, James; Zhu, Lan; Geiger, James; Chun, Eugene; Kissick, David; Hilgart, Mark C; Ogata, Craig; Ishchenko, Andrii; Nagaratnam, Nirupa; Roy-Chowdhury, Shatabdi; Coe, Jesse; Subramanian, Ganesh; Schaffer, Alexander; James, Daniel; Ketwala, Gihan; Venugopalan, Nagarajan; Xu, Shenglan; Corcoran, Stephen; Ferguson, Dale; Weierstall, Uwe; Spence, John C H; Cherezov, Vadim; Fromme, Petra; Fischetti, Robert F; Liu, Wei

    2017-07-01

    Crystal structure determination of biological macromolecules using the novel technique of serial femtosecond crystallography (SFX) is severely limited by the scarcity of X-ray free-electron laser (XFEL) sources. However, recent and future upgrades render microfocus beamlines at synchrotron-radiation sources suitable for room-temperature serial crystallography data collection also. Owing to the longer exposure times that are needed at synchrotrons, serial data collection is termed serial millisecond crystallography (SMX). As a result, the number of SMX experiments is growing rapidly, with a dozen experiments reported so far. Here, the first high-viscosity injector-based SMX experiments carried out at a US synchrotron source, the Advanced Photon Source (APS), are reported. Microcrystals (5-20 µm) of a wide variety of proteins, including lysozyme, thaumatin, phycocyanin, the human A 2A adenosine receptor (A 2A AR), the soluble fragment of the membrane lipoprotein Flpp3 and proteinase K, were screened. Crystals suspended in lipidic cubic phase (LCP) or a high-molecular-weight poly(ethylene oxide) (PEO; molecular weight 8 000 000) were delivered to the beam using a high-viscosity injector. In-house data-reduction (hit-finding) software developed at APS as well as the SFX data-reduction and analysis software suites Cheetah and CrystFEL enabled efficient on-site SMX data monitoring, reduction and processing. Complete data sets were collected for A 2A AR, phycocyanin, Flpp3, proteinase K and lysozyme, and the structures of A 2A AR, phycocyanin, proteinase K and lysozyme were determined at 3.2, 3.1, 2.65 and 2.05 Å resolution, respectively. The data demonstrate the feasibility of serial millisecond crystallography from 5-20 µm crystals using a high-viscosity injector at APS. The resolution of the crystal structures obtained in this study was dictated by the current flux density and crystal size, but upcoming developments in beamline optics and the planned APS-U upgrade will increase the intensity by two orders of magnitude. These developments will enable structure determination from smaller and/or weakly diffracting microcrystals.

  20. Room-temperature serial crystallography at synchrotron X-ray sources using slowly flowing free-standing high-viscosity microstreams.

    PubMed

    Botha, Sabine; Nass, Karol; Barends, Thomas R M; Kabsch, Wolfgang; Latz, Beatrice; Dworkowski, Florian; Foucar, Lutz; Panepucci, Ezequiel; Wang, Meitian; Shoeman, Robert L; Schlichting, Ilme; Doak, R Bruce

    2015-02-01

    Recent advances in synchrotron sources, beamline optics and detectors are driving a renaissance in room-temperature data collection. The underlying impetus is the recognition that conformational differences are observed in functionally important regions of structures determined using crystals kept at ambient as opposed to cryogenic temperature during data collection. In addition, room-temperature measurements enable time-resolved studies and eliminate the need to find suitable cryoprotectants. Since radiation damage limits the high-resolution data that can be obtained from a single crystal, especially at room temperature, data are typically collected in a serial fashion using a number of crystals to spread the total dose over the entire ensemble. Several approaches have been developed over the years to efficiently exchange crystals for room-temperature data collection. These include in situ collection in trays, chips and capillary mounts. Here, the use of a slowly flowing microscopic stream for crystal delivery is demonstrated, resulting in extremely high-throughput delivery of crystals into the X-ray beam. This free-stream technology, which was originally developed for serial femtosecond crystallography at X-ray free-electron lasers, is here adapted to serial crystallography at synchrotrons. By embedding the crystals in a high-viscosity carrier stream, high-resolution room-temperature studies can be conducted at atmospheric pressure using the unattenuated X-ray beam, thus permitting the analysis of small or weakly scattering crystals. The high-viscosity extrusion injector is described, as is its use to collect high-resolution serial data from native and heavy-atom-derivatized lysozyme crystals at the Swiss Light Source using less than half a milligram of protein crystals. The room-temperature serial data allow de novo structure determination. The crystal size used in this proof-of-principle experiment was dictated by the available flux density. However, upcoming developments in beamline optics, detectors and synchrotron sources will enable the use of true microcrystals. This high-throughput, high-dose-rate methodology provides a new route to investigating the structure and dynamics of macromolecules at ambient temperature.

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