Building a learning health system using clinical registers: a non-technical introduction.

PubMed

Ovretveit, John; Nelson, Eugene; James, Brent

2016-10-10

Purpose The purpose of this paper is to describe how clinical registers were designed and used to serve multiple purposes in three health systems, in order to contribute practical experience for building learning healthcare systems. Design/methodology/approach Case description and comparison of the development and use of clinical registries, drawing on participants' experience and published and unpublished research. Findings Clinical registers and new software systems enable fact-based decisions by patients, clinicians, and managers about better care, as well as new and more economical research. Designing systems to present the data for users' daily work appears to be the key to effective use of the potential afforded by digital data. Research limitations/implications The case descriptions draw on the experience of the authors who were involved in the development of the registers, as well as on published and unpublished research. There is limited data about outcomes for patients or cost-effectiveness. Practical implications The cases show the significant investments which are needed to make effective use of clinical register data. There are limited skills to design and apply the digital systems to make the best use of the systems and to reduce their disadvantages. More use can be made of digital data for quality improvement, patient empowerment and support, and for research. Social implications Patients can use their data combined with other data to self-manage their chronic conditions. There are challenges in designing and using systems so that those with lower health and computer literacy and incomes also benefit from these systems, otherwise the digital revolution may increase health inequalities. Originality/value The paper shows three real examples of clinical registers which have been developed as part of their host health systems' strategies to develop learning healthcare systems. The paper gives a simple non-technical introduction and overview for clinicians, managers, policy-advisors and improvers of what is possible and the challenges, and highlights the need to shape the design and implementation of digital infrastructures in healthcare services to serve users.

Survey of piloting factors in V/STOL aircraft with implications for flight control system design

NASA Technical Reports Server (NTRS)

Ringland, R. F.; Craig, S. J.

1977-01-01

Flight control system design factors involved for pilot workload relief are identified. Major contributors to pilot workload include configuration management and control and aircraft stability and response qualities. A digital fly by wire stability augmentation, configuration management, and configuration control system is suggested for reduction of pilot workload during takeoff, hovering, and approach.

Systems Engineering Workshop 2017 | Wind | NREL

Science.gov Websites

Energy for Wind Systems Today Cost and Value of Wind Power-Implications of Wind Turbine Design, János Aaron Smith, PPI Session II: Uncertainty Impacts on Wind Turbine Design and Performance Mitigation of Wind Turbine Design Load Uncertainties, Anand Natarajan, DTU Wind Energy Uncertainty in the Wind

LANDSAT D user data processing study

NASA Technical Reports Server (NTRS)

1976-01-01

The major expected users of the LANDSAT D system and a preliminary system design of their required facilities are investigated. This system design will then be costed in order to provide an estimate of the incremental user costs necessitated by LANDSAT D. One major use of these cost estimates is as part of an overall economic cost/benefit argument being developed for the LANDSAT D system. The implication of this motive is key; the system design (and corresponding cost estimates) must be a credible one, but not necessarily an optimum one.

Cognitive Models of Scientific Work and Their Implications for the Design of Knowledge Delivery Systems.

ERIC Educational Resources Information Center

Mavor, A. S.; And Others

Part of a sustained program that has involved the design of personally tailored information systems responsive to the needs of scientists performing common research and teaching tasks, this project focuses on the procedural and content requirements for accomplishing need diagnosis and presents these requirements as specifications for an…

Implications of complex adaptive systems theory for the design of research on health care organizations

PubMed Central

McDaniel, Reuben R.; Lanham, Holly Jordan; Anderson, Ruth A.

2013-01-01

Background Because health care organizations (HCOs) are complex adaptive systems (CASs), phenomena of interest often are dynamic and unfold in unpredictable ways, and unfolding events are often unique. Researchers of HCOs may recognize that the subject of their research is dynamic; however, their research designs may not take this into account. Researchers may also know that unfolding events are often unique, but their design may not have the capacity to obtain information from meager evidence. Purpose These two concerns led us to examine two ideas from organizational theory: (a) the ideas of K. E. Weick (1993) on organizational design as a verb and (b) the ideas of J. G. March, L. S. Sproull, and M. Tamuz (1991) on learning from samples of one or fewer. In this article, we applied these ideas to develop an enriched perspective of research design for studying CASs. Methodology/Approach We conducted a theoretical analysis of organizations as CASs, identifying relevant characteristics for research designs. We then explored two ideas from organizational theory and discussed the implications for research designs. Findings Weick's idea of “design as a verb” helps in understanding dynamic and process-oriented research design. The idea of “learning from samples of one or fewer” of March, Sproull, and Tamuz provides strategies for research design that enables learning from meager evidence. When studying HCOs, research designs are likely to be more effective when they (a) anticipate change, (b) include tension, (c) capitalize on serendipity, and (d) use an “act-then-look” mind set. Implications for practice are discussed. Practice Implications Practitioners who understand HCOs as CASs will be cautious in accepting findings from studies that treat HCOs mechanistically. They will consider the characteristics of CAS when evaluating the evidence base for practice. Practitioners can use the strategies proposed in this article to stimulate discussion with researchers seeking to conduct research in their HCO. PMID:19322050

Assessment of economic factors affecting the satellite power system. Volume 2: The systems implications of rectenna siting issues

NASA Technical Reports Server (NTRS)

Chapman, P. K.; Bugos, B. J.; Csigi, K. I.; Glaser, P. E.; Schimke, G. R.; Thomas, R. G.

1979-01-01

The feasibility was evaluated of finding potential sites for Solar Power Satellite (SPS) receiving antennas (rectennas) in the continental United States, in sufficient numbers to permit the SPS to make a major contribution to U.S. generating facilities, and to give statistical validity to an assessment of the characteristics of such sites and their implications for the design of the SPS system. It is found that the cost-optimum power output of the SPS does not depend on the particular value assigned to the cost per unit area of a rectenna and its site, as long as it is independent of rectenna area. Many characteristics of the sites chosen affect the optimum design of the rectenna itself.

Getting what they need when they need it. Identifying barriers to information needs of family caregivers to manage dementia-related behavioral symptoms.

PubMed

Werner, Nicole E; Stanislawski, Barbara; Marx, Katherine A; Watkins, Daphne C; Kobayashi, Marissa; Kales, Helen; Gitlin, Laura N

2017-02-22

Consumer health informatics (CHI) such as web-based applications may provide the platform for enabling the over 15 million family caregivers of patients with Alzheimer's Disease or related dementias the information they need when they need it to support behavioral symptom management. However, for CHI to be successful, it is necessary that it be designed to meet the specific information needs of family caregivers in the context in which caregiving occurs. A sociotechnical systems approach to CHI design can help to understand the contextual complexities of family caregiving and account for those complexities in the design of CHI for family caregivers. This study used a sociotechnical systems approach to identify barriers to meeting caregivers' information needs related to the management of dementia-related behavioral symptoms, and to derive design implications that overcome barriers for caregiver-focused web-based platforms. We have subsequently used these design implications to inform the development of a web-based platform, WeCareAdvisor,TM which provides caregivers with information and an algorithm by which to identify and manage behavioral symptoms for which they seek management strategies. We conducted 4 focus groups with family caregivers (N=26) in a Midwestern state. Qualitative content analysis of the data was guided by a sociotechnical systems framework. We identified nine categories of barriers that family caregivers confront in obtaining needed information about behavioral symptom management from which we extrapolated design implications for a web-based platform. Based on interactions within the sociotechnical system, three critical information needs were identified: 1) timely access to information, 2) access to information that is tailored or specific to caregiver's needs and contexts, and 3) usable information that can directly inform how caregivers' manage behaviors. The sociotechnical system framework is a useful approach for identifying information needs of family caregivers to inform design of web-based platforms that are user-centered.

Implications of system usability on intermodal facility design.

DOT National Transportation Integrated Search

2010-08-01

Ensuring good design of intermodal transportation facilities is critical for effective and : satisfactory operation. Passenger use of the facilities is often hindered by inadequate space, a poor : layout, or lack of signage. This project aims to impr...

Human factors in spacecraft design

NASA Technical Reports Server (NTRS)

Harrison, Albert A.; Connors, Mary M.

1990-01-01

This paper describes some of the salient implications of evolving mission parameters for spacecraft design. Among the requirements for future spacecraft are new, higher standards of living, increased support of human productivity, and greater accommodation of physical and cultural variability. Design issues include volumetric allowances, architecture and layouts, closed life support systems, health maintenance systems, recreational facilities, automation, privacy, and decor. An understanding of behavioral responses to design elements is a precondition for critical design decisions. Human factors research results must be taken into account early in the course of the design process.

Work Design Theory: A Review and Critique with Implications for Human Resource Development

ERIC Educational Resources Information Center

Torraco, Richard J.

2005-01-01

Six theoretical perspectives on work design are examined for their contributions to our understanding of how work is organized and designed in organizations: sociotechnical systems theory, process improvement, adaptive structuration theory, the job characteristics model, technostructural change models, and activity theory. A critique of these…

Biomimicry, Biofabrication, and Biohybrid Systems: The Emergence and Evolution of Biological Design.

PubMed

Raman, Ritu; Bashir, Rashid

2017-10-01

The discipline of biological design has a relatively short history, but has undergone very rapid expansion and development over that time. This Progress Report outlines the evolution of this field from biomimicry to biofabrication to biohybrid systems' design, showcasing how each subfield incorporates bioinspired dynamic adaptation into engineered systems. Ethical implications of biological design are discussed, with an emphasis on establishing responsible practices for engineering non-natural or hypernatural functional behaviors in biohybrid systems. This report concludes with recommendations for implementing biological design into educational curricula, ensuring effective and responsible practices for the next generation of engineers and scientists. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

How Can Visual Analytics Assist Investigative Analysis? Design Implications from an Evaluation.

PubMed

Youn-Ah Kang; Görg, Carsten; Stasko, John

2011-05-01

Despite the growing number of systems providing visual analytic support for investigative analysis, few empirical studies of the potential benefits of such systems have been conducted, particularly controlled, comparative evaluations. Determining how such systems foster insight and sensemaking is important for their continued growth and study, however. Furthermore, studies that identify how people use such systems and why they benefit (or not) can help inform the design of new systems in this area. We conducted an evaluation of the visual analytics system Jigsaw employed in a small investigative sensemaking exercise, and compared its use to three other more traditional methods of analysis. Sixteen participants performed a simulated intelligence analysis task under one of the four conditions. Experimental results suggest that Jigsaw assisted participants to analyze the data and identify an embedded threat. We describe different analysis strategies used by study participants and how computational support (or the lack thereof) influenced the strategies. We then illustrate several characteristics of the sensemaking process identified in the study and provide design implications for investigative analysis tools based thereon. We conclude with recommendations on metrics and techniques for evaluating visual analytics systems for investigative analysis.

Problems experienced and envisioned for dynamical physical systems

NASA Technical Reports Server (NTRS)

Ryan, R. S.

1985-01-01

The use of high performance systems, which is the trend of future space systems, naturally leads to lower margins and a higher sensitivity to parameter variations and, therefore, more problems of dynamical physical systems. To circumvent dynamic problems of these systems, appropriate design, verification analysis, and tests must be planned and conducted. The basic design goal is to define the problem before it occurs. The primary approach for meeting this goal is a good understanding and reviewing of the problems experienced in the past in terms of the system under design. This paper reviews many of the dynamic problems experienced in space systems design and operation, categorizes them as to causes, and envisions future program implications, developing recommendations for analysis and test approaches.

Electrical Space Conditioning.

ERIC Educational Resources Information Center

General Electric Co., Cleveland, OH. Large Lamp Dept.

Integrated systems utilizing the heating potential of lighting equipment are discussed in terms of the implications for design and the methods for evaluation and control. General principles cover heat transfer, heat from lamps and luminaires, and control of lighting heat. Suggested systems include--(1) total control systems, (2) bleed-off systems,…

Flight Experience from Space Photovoltaic Concentrator Arrays and its Implication on Terrestrial Concentrator Systems

NASA Technical Reports Server (NTRS)

Piszczor, Michael F., Jr.

2003-01-01

Nearly all photovoltaic solar arrays flown in space have used a planar (non- concentrating) design. However, there have been a few notable exceptions where photovoltaic concentrators have been tested and used as the mission s primary power source. Among these are the success experienced by the SCARLET (Solar Concentrator Array with Refractive Linear Element Technology) concept used to power NASA's Deep Space 1 mission and the problems encountered by the original Boeing 702 reflective trough concentrator design. This presentation will give a brief overview of past photovoltaic concentrator systems that have flown in space, specifically addressing the valuable lessons learned from flight experience, and other viable concentrator concepts that are being proposed for the future. The general trends of this flight experience will be noted and discussed with regard to its implications on terrestrial photovoltaic concentrator designs.

Community Information Systems.

ERIC Educational Resources Information Center

Freeman, Andrew

Information is provided on technological and social trends as background for a workshop designed to heighten the consciousness of workers in community information systems. Initially, the basic terminology is considered in its implications for an integrated perspective of community information systems, with particular attention given to the meaning…

Empirical studies of design software: Implications for software engineering environments

NASA Technical Reports Server (NTRS)

Krasner, Herb

1988-01-01

The empirical studies team of MCC's Design Process Group conducted three studies in 1986-87 in order to gather data on professionals designing software systems in a range of situations. The first study (the Lift Experiment) used thinking aloud protocols in a controlled laboratory setting to study the cognitive processes of individual designers. The second study (the Object Server Project) involved the observation, videotaping, and data collection of a design team of a medium-sized development project over several months in order to study team dynamics. The third study (the Field Study) involved interviews with the personnel from 19 large development projects in the MCC shareholders in order to study how the process of design is affected by organizationl and project behavior. The focus of this report will be on key observations of design process (at several levels) and their implications for the design of environments.

OCTANET--an electronic library network: I. Design and development.

PubMed Central

Johnson, M F; Pride, R B

1983-01-01

The design and development of the OCTANET system for networking among medical libraries in the midcontinental region is described. This system's features and configuration may be attributed, at least in part, to normal evolution of technology in library networking, remote access to computers, and development of machine-readable data bases. Current functions and services of the system are outlined and implications for future developments in computer-based networking are discussed. PMID:6860825

Art, Illusion and the Visual System.

ERIC Educational Resources Information Center

Livingstone, Margaret S.

1988-01-01

Describes the three part system of human vision. Explores the anatomical arrangement of the vision system from the eyes to the brain. Traces the path of various visual signals to their interpretations by the brain. Discusses human visual perception and its implications in art and design. (CW)

Human factors analysis and classification system-HFACS.

DOT National Transportation Integrated Search

2000-02-01

Human error has been implicated in 70 to 80% of all civil and military aviation accidents. Yet, most accident : reporting systems are not designed around any theoretical framework of human error. As a result, most : accident databases are not conduci...

Crystallization of aluminum hydroxide in the aluminum-air battery: Literature review, crystallizer design and results of integrated system tests

NASA Astrophysics Data System (ADS)

Maimoni, A.

1988-03-01

The literature on aluminum trihydroxide crystallization is reviewed and the implications of crystallization on the design and performance of the aluminum-air battery are illustrated. Results of research on hydrargillite crystallization under battery operating conditions at Alcoa Laboratories, Alcan Kingston Laboratories, and Lawrence Livermore National Laboratory are summarized and are applied to the design of an electrolyte management system using lamella settlers for clarification of the electrolyte and product separation. The design principles were validated in a series of experiments that, for the first time in the aluminum-air program, demonstrated continuous operation of an integrated system consisting of cells, crystallizer, and a product-removal system.

Organizational Characteristics of a University: Implications for Design and Use of Information Systems.

ERIC Educational Resources Information Center

Arns, Robert G.

1979-01-01

The ways in which institutional characteristics affect the application and development of administrative information systems are discussed. A cybernetics model is proposed and principles are developed to assist university administrators in distinguishing institutional constraints from shortcomings in the information system. (SF)

Lessons Learned from the San Diego Urban Systemic Project (USP): Implications for Funders and Future Project Designers

ERIC Educational Resources Information Center

St. John, Mark; Heenan, Barbara; Helms, Jenifer

2007-01-01

This brief draws upon the five-year evaluation study of the San Diego Urban Systemic Project (USP) that Inverness Research Associates conducted from 2001 to 2006. The intended audiences for this brief are those interested in investing in, supporting, or designing initiatives that aim to improve math and science education in large urban districts.…

Impact of digital systems technology on man-vehicle systems research

NASA Technical Reports Server (NTRS)

Bretoi, R. N.

1983-01-01

The present study, based on a NASA technology assessment, examines the effect of new technologies on trends in crew-systems design and their implications from the vantage point of man-vehicle systems research. Those technologies that are most relevant to future trends in crew-systems design are considered along with problems associated with the introduction of rapidly changing technologies and systems concepts from a human-factors point of view. The technologies discussed include information processing, displays and controls, flight and propulsion control, flight and systems management, air traffic control, training and simulation, and flight and resource management. The historical evolution of cockpit systems design is used to illustrate past and possible future trends in man-vehicle systems research.

HealthStyles: a new psychographic segmentation system for health care marketers.

PubMed

Endresen, K W; Wintz, J C

1988-01-01

HealthStyles is a new psychographic segmentation system specifically designed for the health care industry. This segmentation system goes beyond traditional geographic and demographic analysis and examines health-related consumer attitudes and behaviors. Four statistically distinct "styles" of consumer health care preferences have been identified. The profiles of the four groups have substantial marketing implications in terms of design and promotion of products and services. Each segment of consumers also has differing expectations of physician behavior.

The Implications of Self-Reporting Systems for Maritime Domain Awareness

DTIC Science & Technology

2006-12-01

SIA), offrent des avantages significatifs comparativement à la poursuite des navires par détecteur ordinaire et que la disponibilité de l’information...reporting system for sea-going vessels that originated in Sweden in the early 1990s. It was designed primarily for safety of life at sea (SOLAS) and...report information is prone to human error and potential malicious altering and the system itself was not designed with these vulnerabilities in mind

Human-computer interaction in distributed supervisory control tasks

NASA Technical Reports Server (NTRS)

Mitchell, Christine M.

1989-01-01

An overview of activities concerned with the development and applications of the Operator Function Model (OFM) is presented. The OFM is a mathematical tool to represent operator interaction with predominantly automated space ground control systems. The design and assessment of an intelligent operator aid (OFMspert and Ally) is particularly discussed. The application of OFM to represent the task knowledge in the design of intelligent tutoring systems, designated OFMTutor and ITSSO (Intelligent Tutoring System for Satellite Operators), is also described. Viewgraphs from symposia presentations are compiled along with papers addressing the intent inferencing capabilities of OFMspert, the OFMTutor system, and an overview of intelligent tutoring systems and the implications for complex dynamic systems.

Improved scaling laws for stage inert mass of space propulsion systems. Volume 2: System modeling and weight data

NASA Technical Reports Server (NTRS)

1971-01-01

Technical models and analytical approaches used to develop the weight data for vehicle system concepts using advanced technology are reported. Weight data are supplied for the following major system elements: engine, pressurization, propellant containers, structural shells and secondary structure, and environmental protection shields for the meteoroid and thermal design requirements. Scaling laws, improved and a simplified set, are developed from the system weight data. The laws consider the implications of the major design parameters and mission requirements on the stage inert mass.

Superstorm Sandy: Implications For Designing A PostCyber Attack Power Restoration System

DTIC Science & Technology

2016-03-31

for such progress. Phillip Allison, “ Cloak and Secure Your Critical Infrastructure, ICS and SCADA Systems: Building Security into Your Industrial...TechSvcs/Multi-stateFleetResponseWorkshopReport-02-21-13.pdf. Allison, Phillip. “ Cloak and Secure Your Critical Infrastructure, ICS and SCADA Systems

Early Design Choices: Capture, Model, Integrate, Analyze, Simulate

NASA Technical Reports Server (NTRS)

Malin, Jane T.

2004-01-01

I. Designs are constructed incrementally to meet requirements and solve problems: a) Requirements types: objectives, scenarios, constraints, ilities. etc. b) Problem/issue types: risk/safety, cost/difficulty, interaction, conflict, etc. II. Capture requirements, problems and solutions: a) Collect design and analysis products and make them accessible for integration and analysis; b) Link changes in design requirements, problems and solutions; and c) Harvest design data for design models and choice structures. III. System designs are constructed by multiple groups designing interacting subsystems a) Diverse problems, choice criteria, analysis methods and point solutions. IV. Support integration and global analysis of repercussions: a) System implications of point solutions; b) Broad analysis of interactions beyond totals of mass, cost, etc.

A Surveillance and Targeting System for an Unmanned Ground Vehicle

DTIC Science & Technology

1990-08-01

CHARACTERISTICS - SELECTABLE INFRASONIC AND ULTRASONIC FREQUENCY SHIFTING CAPABILITY - SUPER-BINAURAL CONFIGURATION ANGLE AND PICKUP SEPARATION GREATER THAN...HUMAN HEAD - VARIABLE GAIN WITH CLIPPING - INTEGRATABLE INTO TOV OPERATOR HELMET - CONTROL INTERFACE: VOLUME UP/DOWN, SONIC ON/OFF, ULTRA ON/OFF... INFRA ON/OFF, BOOST HI/MED/OFF ----- UGV/TOV ----- ---- AUVS/DAYTON ---- LASER SAFETY IMPLICATIONS IMPLICATIONS FOR DESIGN: - POWER UP SEQUENCE - ABORT

Multimodal and ubiquitous computing systems: supporting independent-living older users.

PubMed

Perry, Mark; Dowdall, Alan; Lines, Lorna; Hone, Kate

2004-09-01

We document the rationale and design of a multimodal interface to a pervasive/ubiquitous computing system that supports independent living by older people in their own homes. The Millennium Home system involves fitting a resident's home with sensors--these sensors can be used to trigger sequences of interaction with the resident to warn them about dangerous events, or to check if they need external help. We draw lessons from the design process and conclude the paper with implications for the design of multimodal interfaces to ubiquitous systems developed for the elderly and in healthcare, as well as for more general ubiquitous computing applications.

Design of a Computer-Adaptive Test to Measure English Literacy and Numeracy in the Singapore Workforce: Considerations, Benefits, and Implications

ERIC Educational Resources Information Center

Jacobsen, Jared; Ackermann, Richard; Eguez, Jane; Ganguli, Debalina; Rickard, Patricia; Taylor, Linda

2011-01-01

A computer adaptive test (CAT) is a delivery methodology that serves the larger goals of the assessment system in which it is embedded. A thorough analysis of the assessment system for which a CAT is being designed is critical to ensure that the delivery platform is appropriate and addresses all relevant complexities. As such, a CAT engine must be…

Supporting cognition in systems biology analysis: findings on users' processes and design implications.

PubMed

Mirel, Barbara

2009-02-13

Current usability studies of bioinformatics tools suggest that tools for exploratory analysis support some tasks related to finding relationships of interest but not the deep causal insights necessary for formulating plausible and credible hypotheses. To better understand design requirements for gaining these causal insights in systems biology analyses a longitudinal field study of 15 biomedical researchers was conducted. Researchers interacted with the same protein-protein interaction tools to discover possible disease mechanisms for further experimentation. Findings reveal patterns in scientists' exploratory and explanatory analysis and reveal that tools positively supported a number of well-structured query and analysis tasks. But for several of scientists' more complex, higher order ways of knowing and reasoning the tools did not offer adequate support. Results show that for a better fit with scientists' cognition for exploratory analysis systems biology tools need to better match scientists' processes for validating, for making a transition from classification to model-based reasoning, and for engaging in causal mental modelling. As the next great frontier in bioinformatics usability, tool designs for exploratory systems biology analysis need to move beyond the successes already achieved in supporting formulaic query and analysis tasks and now reduce current mismatches with several of scientists' higher order analytical practices. The implications of results for tool designs are discussed.

The Human Factors Analysis and Classification System : HFACS : final report.

DOT National Transportation Integrated Search

2000-02-01

Human error has been implicated in 70 to 80% of all civil and military aviation accidents. Yet, most accident reporting systems are not designed around any theoretical framework of human error. As a result, most accident databases are not conducive t...

System issues and considerations associated with design of ground mobile strategic satellite communication terminals

NASA Astrophysics Data System (ADS)

Poliakon, J. A.

The current national defense doctrine calls for increased use of ground mobile strategic satellite communication earth terminals. This paper discusses some of the key communication terminal system issues and considerations associated with the design of nuclear hardened strategic ground mobile earth terminals. It considers system requirements such as nuclear hardness, rapid mobility, low profile, signal interference resistance, high availability, and long term independent operation. It also discusses impacts and implications associated with these requirements when imposed on a satellite earth terminal. It gives special focus to the ramifications of imposing mobility on earth terminals and its relationship to the system design approach used to arrive at an optimal system solution.

Designing an Advanced Instructional Design Advisor: Possibilities for Automation. Volume 3

DTIC Science & Technology

1991-05-01

system (Spec. Rep. NPRDC- SR-83-13). San Diego, CA: Navy Personnel Research and Development Center. Dawkins , R. (1976). The selfish gene . Oxford...instructional methods that keep the idea alive will change in corresponding ways. (See Dawkins (1976) for a discussion of related ideas.) The implications of

How do local stakeholders respond to the uncertain implications of an innovative flood infrastructure project?

NASA Astrophysics Data System (ADS)

van den Hoek, Ronald; Brugnach, Marcela; Hoekstra, Arjen

2013-04-01

In the 20th century, flood management was dominated by rigid structures - such as dikes and dams - which intend to strictly regulate and control water systems. Although the application of these rigid structures has been successful in the recent past, their negative implications for ecosystems and natural processes is often not properly taken into account. Therefore, flood management practices are currently moving towards more nature-inclusive approaches. Building with Nature (BwN) is such a new approach of nature-inclusive flood management in the Netherlands, which aims to utilize natural dynamics (e.g., wind and currents) and natural materials (e.g., sediment and vegetation) for the realization of effective flood infrastructure, while providing opportunities for nature development. However, the natural dynamics driving a project based on BwN design principles are inherently unpredictable. Furthermore, our factual knowledge base regarding the socio-ecological system in which the BwN initiative is implemented is incomplete. Moreover, in recent years, it is increasingly aimed for by decision-makers to involve local stakeholders in the development of promising flood management initiatives. These stakeholders and other actors involved can have diverging views regarding the project, can perceive unanticipated implications and could choose unforeseen action paths. In short, while a project based on BwN design principles - like any human intervention - definitely has implications for the socio-ecological system, both the extent to which these particular implications will occur and the response of stakeholders are highly uncertain. In this paper, we study the Safety Buffer Oyster Dam case - a BwN pilot project - and address the interplay between the project's implications, the uncertainties regarding these implications and the action paths chosen by the local stakeholders and project team. We determine how the implications of the Safety Buffer project are viewed by local stakeholders, identify the frames and uncertainties related to these implications, and classify these uncertainties according to their nature and level. We describe which action paths are chosen by the local stakeholders and project team regarding the implications identified. Our research shows that there is a correspondence between the level of uncertainty about the implications identified and the action paths chosen by the actors involved. This suggests that the inherent deep uncertainty in projects based on BwN principles calls for more adaptable and flexible strategies to cope with the implications of these initiatives.

Five schools of thought about complexity: Implications for design and process science

DOE Office of Scientific and Technical Information (OSTI.GOV)

Warfield, J.N.

1996-12-31

The prevalence of complexity is a fact of life in virtually all aspects of system design today. Five schools of thought concerning complexity seem to be present in areas where people strive to gain more facility with difficult issues: (1) Interdisciplinary or Cross-Disciplinary {open_quotes}approaches{close_quotes} or {open_quotes}methods{close_quotes} (fostered by the Association for Integrative Studies, a predominantly liberal-arts faculty activity), (2) Systems Dynamics (fostered by Jay Forrester, Dennis Meadows, Peter Senge, and others closely associated with MIT), (3) Chaos Theory (arising in small groups in many locations), (4) Adaptive Systems Theory (predominantly associated with the Santa Fe Institute), and (5) The Structure-Basedmore » school (developed by the author, his colleagues and associates). A comparison of these five schools of thought will be offered, in order to show the implications of them upon the development and application of design and process science. The following criteria of comparison will be used: (a) how complexity is defined, (b) analysis versus synthesis, (c) potential for acquiring practical competence in coping with complexity, and (d) relationship to underlying formalisms that facilitate computer assistance in applications. Through these comparisons, the advantages and disadvantages of each school of thought can be clarified, and the possibilities of changes in the educational system to provide for the management of complexity in system design can be articulated.« less

Advanced Vehicle Concepts and Implications for NextGen

NASA Technical Reports Server (NTRS)

Blake, Matt; Smith, Jim; Wright, Ken; Mediavilla Ricky; Kirby, Michelle; Pfaender, Holger; Clarke, John-Paul; Volovoi, Vitali; Dorbian, Christopher; Ashok, Akshay;

Fault Management Design Strategies

NASA Technical Reports Server (NTRS)

Day, John C.; Johnson, Stephen B.

2014-01-01

Development of dependable systems relies on the ability of the system to determine and respond to off-nominal system behavior. Specification and development of these fault management capabilities must be done in a structured and principled manner to improve our understanding of these systems, and to make significant gains in dependability (safety, reliability and availability). Prior work has described a fundamental taxonomy and theory of System Health Management (SHM), and of its operational subset, Fault Management (FM). This conceptual foundation provides a basis to develop framework to design and implement FM design strategies that protect mission objectives and account for system design limitations. Selection of an SHM strategy has implications for the functions required to perform the strategy, and it places constraints on the set of possible design solutions. The framework developed in this paper provides a rigorous and principled approach to classifying SHM strategies, as well as methods for determination and implementation of SHM strategies. An illustrative example is used to describe the application of the framework and the resulting benefits to system and FM design and dependability.

Unreliable numbers: error and harm induced by bad design can be reduced by better design

PubMed Central

Thimbleby, Harold; Oladimeji, Patrick; Cairns, Paul

2015-01-01

Number entry is a ubiquitous activity and is often performed in safety- and mission-critical procedures, such as healthcare, science, finance, aviation and in many other areas. We show that Monte Carlo methods can quickly and easily compare the reliability of different number entry systems. A surprising finding is that many common, widely used systems are defective, and induce unnecessary human error. We show that Monte Carlo methods enable designers to explore the implications of normal and unexpected operator behaviour, and to design systems to be more resilient to use error. We demonstrate novel designs with improved resilience, implying that the common problems identified and the errors they induce are avoidable. PMID:26354830

When a Better Interface and Easy Navigation Aren't Enough: Examining the Information Architecture in a Law Enforcement Agency.

ERIC Educational Resources Information Center

Hauck, Roslin V.; Weisband, Suzanne

2002-01-01

Describes two database systems in a law enforcement agency: one is a legacy, text-based system with cumbersome navigation; the newer system is a graphical user interface with simplified navigation. Discusses results of two user studies that showed personnel preferred the older more familiar system and considers implications for system design and…

Implications of Artificial Intelligence for End User Use of Online Systems.

ERIC Educational Resources Information Center

Smith, Linda C.

1980-01-01

Reviewed are several studies which demonstrate how artificial intelligence techniques can be applied in the design of end user-oriented interfaces (which would eliminate the need for an intermediary) to existing online systems, as well as in the development of future generations of online systems intended for the end user. (Author/SW)

Privacy and Information Systems: An Argument and an Implementation.

ERIC Educational Resources Information Center

Hellman, J. J.

The report is presented in two parts. The first examines the social and technical implications of information systems vis a vis the individual's ability to control the dissemination of information about himself. It is argued that information systems must incorporate certain properties in their initial design in order to safeguard man's…

Aircraft Alerting Systems Standardization Study. Phase IV. Accident Implications on Systems Design.

DTIC Science & Technology

1982-06-01

computing and processing to assimilate and process status informa- 5 tion using...provided with capabilities in computing and processing , sensing, interfacing, and controlling and displaying. 17 o Computing and Processing - Algorithms...alerting system to perform a flight status monitor function would require additional sensinq, computing and processing , interfacing, and controlling

Implications of complex adaptive systems theory for the design of research on health care organizations.

PubMed

McDaniel, Reuben R; Lanham, Holly Jordan; Anderson, Ruth A

2009-01-01

Because health care organizations (HCOs) are complex adaptive systems (CASs), phenomena of interest often are dynamic and unfold in unpredictable ways, and unfolding events are often unique. Researchers of HCOs may recognize that the subject of their research is dynamic; however, their research designs may not take this into account. Researchers may also know that unfolding events are often unique, but their design may not have the capacity to obtain information from meager evidence. These two concerns led us to examine two ideas from organizational theory: (a) the ideas of K. E. Weick (1993) on organizational design as a verb and (b) the ideas of J. G. March, L. S. Sproull, and M. Tamuz (1991) on learning from samples of one or fewer. In this article, we applied these ideas to develop an enriched perspective of research design for studying CASs. We conducted a theoretical analysis of organizations as CASs, identifying relevant characteristics for research designs. We then explored two ideas from organizational theory and discussed the implications for research designs. Weick's idea of "design as a verb" helps in understanding dynamic and process-oriented research design. The idea of "learning from samples of one or fewer" of March, Sproull, and Tamuz provides strategies for research design that enables learning from meager evidence. When studying HCOs, research designs are likely to be more effective when they (a) anticipate change, (b) include tension, (c) capitalize on serendipity, and (d) use an "act-then-look" mind set. Implications for practice are discussed. Practitioners who understand HCOs as CASs will be cautious in accepting findings from studies that treat HCOs mechanistically. They will consider the characteristics of CAS when evaluating the evidence base for practice. Practitioners can use the strategies proposed in this article to stimulate discussion with researchers seeking to conduct research in their HCO.

Common Cause Failure Modeling: Aerospace Versus Nuclear

NASA Technical Reports Server (NTRS)

Stott, James E.; Britton, Paul; Ring, Robert W.; Hark, Frank; Hatfield, G. Spencer

2010-01-01

Aggregate nuclear plant failure data is used to produce generic common-cause factors that are specifically for use in the common-cause failure models of NUREG/CR-5485. Furthermore, the models presented in NUREG/CR-5485 are specifically designed to incorporate two significantly distinct assumptions about the methods of surveillance testing from whence this aggregate failure data came. What are the implications of using these NUREG generic factors to model the common-cause failures of aerospace systems? Herein, the implications of using the NUREG generic factors in the modeling of aerospace systems are investigated in detail and strong recommendations for modeling the common-cause failures of aerospace systems are given.

Implications of Contingency Planning Support for Weather and Icing Information

NASA Technical Reports Server (NTRS)

Vigeant-Langlois, Laurence; Hansman, R. John, Jr.

2003-01-01

A human-centered systems analysis was applied to the adverse aircraft weather encounter problem in order to identify desirable functions of weather and icing information. The importance of contingency planning was identified as emerging from a system safety design methodology as well as from results of other aviation decision-making studies. The relationship between contingency planning support and information on regions clear of adverse weather was investigated in a scenario- based analysis. A rapid prototype example of the key elements in the depiction of icing conditions was developed in a case study, and the implications for the components of the icing information system were articulated.

System analysis approach to deriving design criteria (Loads) for Space Shuttle and its payloads. Volume 2: Typical examples

NASA Technical Reports Server (NTRS)

Ryan, R. S.; Bullock, T.; Holland, W. B.; Kross, D. A.; Kiefling, L. A.

1981-01-01

The achievement of an optimized design from the system standpoint under the low cost, high risk constraints of the present day environment was analyzed. Space Shuttle illustrates the requirement for an analysis approach that considers all major disciplines (coupling between structures control, propulsion, thermal, aeroelastic, and performance), simultaneously. The Space Shuttle and certain payloads, Space Telescope and Spacelab, are examined. The requirements for system analysis approaches and criteria, including dynamic modeling requirements, test requirements, control requirements, and the resulting design verification approaches are illustrated. A survey of the problem, potential approaches available as solutions, implications for future systems, and projected technology development areas are addressed.

FASTBUS Slaves: a designers view

DOE Office of Scientific and Technical Information (OSTI.GOV)

Downing, R.W.

1981-10-01

Although FASTBUS has features built into it which allow complex interconnections and multiple Masters, the rules for implementing Slaves are very simple. The first time designer of Slave Modules should not be intimidated by the 200 pages of the FASTBUS document. About 90% of the specification is associated with system implications that do not impact Slave design. This paper will review the basic logic and timing requirements for FASTBUS Slave design. Also, some examples of implementation will be shown. The discussion which follows assumes that mastership of the bus has been gained. Bus arbitration, system interconnection, message routing, etc. aremore » separate topics and will not be discussed here. These topics affect only the design of devices which operate at the system level since FASTBUS Slave modules have been specified to be completely transparent to these system considerations.« less

Reciprocity in Online Markets: Empirical Studies of Auction and Barter Markets

ERIC Educational Resources Information Center

Ye, Shun

2013-01-01

My dissertation seeks to understand how reciprocity affects transaction outcomes and mechanism design in online markets. The first essay examines negative reciprocity illustrated as feedback-revoking behavior in the eBay auction market, focusing on its impact and implications for reputation system design. I utilize the biggest policy change of…

The Brazilian Experience with Agroecological Extension: A Critical Analysis of Reform in a Pluralistic Extension System

ERIC Educational Resources Information Center

Diesel, Vivien; Miná Dias, Marcelo

2016-01-01

Purpose: To analyze the Brazilian experience in designing and implementing a recent extension policy reform based on agroecology, and reflect on its wider theoretical implications for extension reform literature. Design/methodology/approach: Using a critical public analysis we characterize the evolution of Brazilian federal extension policy…

State Information Systems. No Child Left Behind Policy Brief.

ERIC Educational Resources Information Center

Snow-Renner, Ravay; Torrence, Marga

The newly revised Elementary and Secondary Education Act (ESEA 2001) has sweeping implications for how states collect, analyze, and use data about school and system performance. Policymakers must take a hard look at the design and capacity of their states' data systems, and determine what changes will have to be made to meet the requirements of…

A Systems Model Comparing Australian and Chinese HRM Education

ERIC Educational Resources Information Center

Davidson, Paul; Tsakissiris, Jane; Guo, Yuanyuan

2017-01-01

This paper explores the implications for learning design in HRM education in the 21st century. An open systems perspective is used to argue the importance of establishing productive relationships between academia, professional associations, regulators and industry (resource inputs) to support the creation of optimal learning environments (the…

Intelligent Conduct of Fire Trainer: Intelligent Technology Applied to Simulator-Based Training.

ERIC Educational Resources Information Center

Newman, Denis; And Others

1989-01-01

Describes an intelligent tutoring system (ITS) that demonstrates how intelligent feedback can enhance conventional simulation-based training. An explanation is given of the Intelligent Conduct of Fire Trainer (INCOFT), which was designed to provide training exercises for soldiers operating the PATRIOT missile system, and its implications for…

APPLICATION OF THE ELECTROMAGNETIC BOREHOLE FLOWMETER

EPA Science Inventory

Spatial variability of saturated zone hydraulic properties has important implications with regard to sampling wells for water quality parameters, use of conventional methods to estimate transmissivity, and remedial system design. Characterization of subsurface heterogeneity requ...

Design requirements for SRB production control system. Volume 2: System requirements and conceptual description

NASA Technical Reports Server (NTRS)

1981-01-01

In the development of the business system for the SRB automated production control system, special attention had to be paid to the unique environment posed by the space shuttle. The issues posed by this environment, and the means by which they were addressed, are reviewed. The change in management philosphy which will be required as NASA switches from one-of-a-kind launches to multiple launches is discussed. The implications of the assembly process on the business system are described. These issues include multiple missions, multiple locations and facilities, maintenance and refurbishment, multiple sources, and multiple contractors. The implications of these aspects on the automated production control system are reviewed including an assessment of the six major subsystems, as well as four other subsystem. Some general system requirements which flow through the entire business system are described.

Personalizing knowledge delivery services: a conceptual framework

NASA Technical Reports Server (NTRS)

Majchrzak, Ann; Chelleppa, Ramnath K.; Cooper, Lynne P.; Hars, Alexander

2003-01-01

Consistent with the call of the Minnesota Symposium for new theory in knowledge management, we offer a new conceptualization of Knowledge Management Systems (KMS) as a portfolio of personalized knowledge delivery services. Borrowing from research on online consumer behavior, we describe the challenges imposed by personalized knowledge delivery services, and suggest design parameters that can help to overcome these challenges. We develop our design constructs through a set of hypotheses and discuss the research implications of our new conceptualization. Finally, we describe practical implications suggested by our conceptualization - practical suggestions that we hope to gain some experience with as part of an ongoing action research project at our partner organization.

Space Station automated systems testing/verification and the Galileo Orbiter fault protection design/verification

NASA Technical Reports Server (NTRS)

Landano, M. R.; Easter, R. W.

1984-01-01

Aspects of Space Station automated systems testing and verification are discussed, taking into account several program requirements. It is found that these requirements lead to a number of issues of uncertainties which require study and resolution during the Space Station definition phase. Most, if not all, of the considered uncertainties have implications for the overall testing and verification strategy adopted by the Space Station Program. A description is given of the Galileo Orbiter fault protection design/verification approach. Attention is given to a mission description, an Orbiter description, the design approach and process, the fault protection design verification approach/process, and problems of 'stress' testing.

A Journey on Refining Rules for Online Discussion: Implications for the Design of Learning Management Systems

ERIC Educational Resources Information Center

Chen, Der-Thanq; Wang, Yu-Mei; Hung, David

2009-01-01

Research on asynchronous online discussions has primarily focused on their efficacy in relation to learning outcomes. Rarely are there investigations on how the design of online learning activities or how discussions could be incorporated into student learning experience. We contend that successful online activities need careful and meticulous…

Social Representations of Cybersecurity by University Students and Implications for Instructional Design

ERIC Educational Resources Information Center

Pawlowski, Suzanne D.; Jung, Yoonhyuk

2015-01-01

Cybersecurity has become an essential topic in introductory information systems (IS) core courses. As an aid to course design, the exploratory research in this paper uses a social representations lens to elucidate the perceptions of cybersecurity and cybersecurity threats held by students. Analysis of qualitative survey data from 152 students at a…

A review of human-automation interaction and lessons learned

DOT National Transportation Integrated Search

2006-10-01

This report reviews 37 accidents in aviation, other vehicles, process control and other complex systems where human-automation interaction is involved. Implications about causality with respect to design, procedures, management and training are drawn...

Effective depth of soil compaction in relation to applied compactive energy.

DOT National Transportation Integrated Search

2015-02-01

The determination of appropriate lift thickness used in the embankment construction has important economic : and engineering implications in the design, construction, and performance of transportation systems. Department : of Transportations (DOTs) a...

New computing systems, future computing environment, and their implications on structural analysis and design

NASA Technical Reports Server (NTRS)

Noor, Ahmed K.; Housner, Jerrold M.

1993-01-01

Recent advances in computer technology that are likely to impact structural analysis and design of flight vehicles are reviewed. A brief summary is given of the advances in microelectronics, networking technologies, and in the user-interface hardware and software. The major features of new and projected computing systems, including high performance computers, parallel processing machines, and small systems, are described. Advances in programming environments, numerical algorithms, and computational strategies for new computing systems are reviewed. The impact of the advances in computer technology on structural analysis and the design of flight vehicles is described. A scenario for future computing paradigms is presented, and the near-term needs in the computational structures area are outlined.

A Factor Analytic Investigation of the BASC-2 Behavioral and Emotional Screening System Parent Form: Psychometric Properties, Practical Implications, and Future Directions

ERIC Educational Resources Information Center

Dowdy, Erin; Chin, Jenna K.; Twyford, Jennifer M.; Dever, Bridget V.

2011-01-01

The Behavior Assessment System for Children, Second Edition (BASC-2) Behavioral and Emotional Screening System Parent Form (BESS Parent; Kamphaus & Reynolds, 2007) is a recently developed instrument designed to identify behavioral and emotional risk in students. To describe the underlying factor structure for this instrument, exploratory (EFA)…

A watershed-based environmental and regulatory data analysis system for the forest products industry

Treesearch

John Beebe

2012-01-01

A watershed-based data analysis system was created as a tool for forest product companies to better understand potential implications from environmental regulations. Also known as the Receiving Water Database (RWDB), this data system was designed with the purpose of assisting companies that own pulp and paper mills, wood product facilities, and commercial timberlands...

Designing for adaptation to novelty and change: functional information, emergent feature graphics, and higher-level control.

PubMed

Hajdukiewicz, John R; Vicente, Kim J

2002-01-01

Ecological interface design (EID) is a theoretical framework that aims to support worker adaptation to change and novelty in complex systems. Previous evaluations of EID have emphasized representativeness to enhance generalizability of results to operational settings. The research presented here is complementary, emphasizing experimental control to enhance theory building. Two experiments were conducted to test the impact of functional information and emergent feature graphics on adaptation to novelty and change in a thermal-hydraulic process control microworld. Presenting functional information in an interface using emergent features encouraged experienced participants to become perceptually coupled to the interface and thereby to exhibit higher-level control and more successful adaptation to unanticipated events. The absence of functional information or of emergent features generally led to lower-level control and less success at adaptation, the exception being a minority of participants who compensated by relying on analytical reasoning. These findings may have practical implications for shaping coordination in complex systems and fundamental implications for the development of a general unified theory of coordination for the technical, human, and social sciences. Actual or potential applications of this research include the design of human-computer interfaces that improve safety in complex sociotechnical systems.

Research on the Development of Ecological Concepts and Conceptual Systems: Implications for the Elementary Educator.

ERIC Educational Resources Information Center

Cothron, Julia H.; Thompson, Ertle

Student variables which influence attainment of ecological concepts and conceptual systems were investigated. Researcher-designed paper/pencil and free-sort categorization tests were administered to 256 Science Curriculum Improvement Study (SCIS) students in grades 4-6. Findings are: (1) grade and ability, not sex, influenced concept attainment…

A Study of Students' Reasoning about Probabilistic Causality: Implications for Understanding Complex Systems and for Instructional Design

ERIC Educational Resources Information Center

Grotzer, Tina A.; Solis, S. Lynneth; Tutwiler, M. Shane; Cuzzolino, Megan Powell

2017-01-01

Understanding complex systems requires reasoning about causal relationships that behave or appear to behave probabilistically. Features such as distributed agency, large spatial scales, and time delays obscure co-variation relationships and complex interactions can result in non-deterministic relationships between causes and effects that are best…

Information Systems Technician Rating Stakeholders: Implications for Effective Performance

DTIC Science & Technology

2011-01-01

DeSanctis, and Borge Obel. (2006). Organizational Design: A Step-by-Step Approach. Cambridge, UK: Cambridge University Press. Carroll, G . R., and M...manpower, personnel, and training processes for managing the information systems technician (IT) rating and the effects of these different stakeholders...Strategic Human Resource Management and Management Structure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 Organizational

Conference Proceedings of Operational Loads Data Held at Sienna, Italy on 2-6 April 1984

DTIC Science & Technology

1984-08-01

new designs , e.g. highly agile, unconventional lay-outs, largely constructed of composite materials and heavily dependent upon active control ...significance of severe discrete gusts at low level, or the fatigue implications of flight control system design characteristics. For all these reasons, we... control technology is clearly going to have a major impact on military aircraft design . User pressure for greater structural efficiency is going to increase

Integrated Flight Performance Analysis of a Launch Abort System Concept

NASA Technical Reports Server (NTRS)

Tartabini, Paul V.

2007-01-01

This paper describes initial flight performance analyses conducted early in the Orion Project to support concept feasibility studies for the Crew Exploration Vehicle s Launch Abort System (LAS). Key performance requirements that significantly affect abort capability are presented. These requirements have implications on sizing the Abort Motor, tailoring its thrust profile to meet escape requirements for both launch pad and high drag/high dynamic pressure ascent aborts. Additional performance considerations are provided for the Attitude Control Motor, a key element of the Orion LAS design that eliminates the need for ballast and provides performance robustness over a passive control approach. Finally, performance of the LAS jettison function is discussed, along with implications on Jettison Motor sizing and the timing of the jettison event during a nominal mission. These studies provide an initial understanding of LAS performance that will continue to evolve as the Orion design is matured.

Shuttle Radar Topography Mission (SRTM) Flight System Design and Operations Overview

NASA Technical Reports Server (NTRS)

Shen, Yuhsyen; Shaffer, Scott J.; Jordan, Rolando L.

2000-01-01

This paper provides an overview of the Shuttle Radar Topography Mission (SRTM), with emphasis on flight system implementation and mission operations from systems engineering perspective. Successfully flown in February, 2000, the SRTM's primary payload consists of several subsystems to form the first spaceborne dual-frequency (C-band and X-band) fixed baseline interferometric synthetic aperture radar (InSAR) system, with the mission objective to acquire data sets over 80% of Earth's landmass for height reconstruction. The paper provides system architecture, unique design features, engineering budgets, design verification, in-flight checkout and data acquisition of the SRTM payload, in particular for the C-band system. Mission operation and post-mission data processing activities are also presented. The complexity of the SRTM as a system, the ambitious mission objective, the demanding requirements and the high interdependency between multi-disciplined subsystems posed many challenges. The engineering experience and the insight thus gained have important implications for future spaceborne interferometric SAR mission design and implementation.

Factors which Limit the Value of Additional Redundancy in Human Rated Launch Vehicle Systems

NASA Technical Reports Server (NTRS)

Anderson, Joel M.; Stott, James E.; Ring, Robert W.; Hatfield, Spencer; Kaltz, Gregory M.

2008-01-01

The National Aeronautics and Space Administration (NASA) has embarked on an ambitious program to return humans to the moon and beyond. As NASA moves forward in the development and design of new launch vehicles for future space exploration, it must fully consider the implications that rule-based requirements of redundancy or fault tolerance have on system reliability/risk. These considerations include common cause failure, increased system complexity, combined serial and parallel configurations, and the impact of design features implemented to control premature activation. These factors and others must be considered in trade studies to support design decisions that balance safety, reliability, performance and system complexity to achieve a relatively simple, operable system that provides the safest and most reliable system within the specified performance requirements. This paper describes conditions under which additional functional redundancy can impede improved system reliability. Examples from current NASA programs including the Ares I Upper Stage will be shown.

Installation of a variable-angle spectrometer system for monitoring diffuse and global solar radiation

NASA Astrophysics Data System (ADS)

Ormachea, O.; Abrahamse, A.; Tolavi, N.; Romero, F.; Urquidi, O.; Pearce, J. M.; Andrews, R.

2013-11-01

We report on the design and installation of a spectrometer system for monitoring solar radiation in Cochabamba, Bolivia. Both the light intensity and the spectral distribution affect the power produced by a photovoltaic device. Local variations in the solar spectrum (especially compared to the AM1.5 standard) may have important implications for device optimization and energy yield estimation. The spectrometer system, based on an Ocean Optics USB4000 (300-900nm) spectrometer, was designed to increase functionality. Typically systems only record the global horizontal radiation. Our system moves a fiber-optic cable 0-90 degrees and takes measurements in 9 degree increments. Additionally, a shadow band allows measurement of the diffuse component of the radiation at each position. The electronic controls utilize an Arduino UNO microcontroller to synchronizes the movement of two PAP bipolar (stepper) motors with the activation of the spectrometer via an external trigger. The spectrometer was factory calibrated for wavelength and calibrated for absolute irradiance using a Sellarnet SL1-Cal light source. We present preliminary results from data taken March-June, 2013, and comment on implications for PV devices in Cochabamba.

A Systems Approach to Public School Reform: Implications for the Use of Social Systems Design in a Small Rural School

ERIC Educational Resources Information Center

Rawlins, Holly

2007-01-01

How can a community ensure that its public schools reflect local values and beliefs about education? The complexities involved in the reform of existing public schools, or the creation of a new system of schooling, have caused some researchers to explore new methodological avenues to change (Banathy, 1991; Duffy, Rogerson, & Blick, 2000;…

System security in the space flight operations center

NASA Technical Reports Server (NTRS)

Wagner, David A.

1988-01-01

The Space Flight Operations Center is a networked system of workstation-class computers that will provide ground support for NASA's next generation of deep-space missions. The author recounts the development of the SFOC system security policy and discusses the various management and technology issues involved. Particular attention is given to risk assessment, security plan development, security implications of design requirements, automatic safeguards, and procedural safeguards.

Shale Frac Sequential Flowback Analyses and Reuse Implications, March 30, 2011

EPA Pesticide Factsheets

Water re-use challenges and solutions have direct and indirect influences in the design of hydraulic fracturing fluid systems and products used in High Volume, High Rate (HVHR) hydraulic fracturing of shale wells (1,2).

APPLICATION OF THE ELECTROMAGNETIC BOREHOLE FLOWMETER (EPA/600/R-98/058)

EPA Science Inventory

Spatial variability of saturated zone hydraulic properties has important implications with regard to sampling wells for water quality parameters, use of conventional methods to estimate transmissivity, and remedial system design. Characterization of subsurface heterogeneity requi...

APPLICATION OF THE ELECTROMAGNETIC BOREHOLE FLOWMETER (EPA/600/SR-98/058)

EPA Science Inventory

Spatial variability of saturated zone hydraulic properties has important implications with regard to sampling wells for water quality parameters, use of conventional methods to estimate transmissivity, and remedial system design. Characterization of subsurface heterogeneity requi...

Essential use cases for pedagogical patterns

NASA Astrophysics Data System (ADS)

Derntl, Michael; Botturi, Luca

2006-06-01

Coming from architecture, through computer science, pattern-based design spread into other disciplines and is nowadays recognized as a powerful way of capturing and reusing effective design practice. However, current pedagogical pattern approaches lack widespread adoption, both by users and authors, and are still limited to individual initiatives. This paper contributes to creating a shared understanding of what a pattern system is by defining the key terms. Moreover, the paper builds upon and extends a set of existing functional and non-functional requirements for pattern systems, adds structure to these requirements, and derives essential use cases following a goal-based approach for both pattern maintenance and pattern application. Finally, implications concerning the pedagogical use of pattern-based design are drawn, concluding that a stronger focus on the underlying (pedagogical) value system is required in order to make a pattern system a meaningful tool for effective educational design.

Meaning profiles of dwellings, pathways, and metaphors in design: implications for education

NASA Astrophysics Data System (ADS)

Casakin, Hernan; Kreitler, Shulamith

2017-11-01

The study deals with the roles and interrelations of the meaning-based assessments of dwellings, pathways and metaphors in design performance. It is grounded in the Meaning Theory [Kreitler, S., and H. Kreitler. 1990. The Cognitive Foundations of Personality Traits. New York: Plenum], which enables identifying the cognitive contents and processes underlying cognitive performance in different domains, thus rendering them more accessible to educational training. The objectives were to identify the components of the meaning profiles of dwellings, pathways, and metaphors as perceived by design students; to analyse their interrelations; and to examine which of the identified components of these constructs serve as best predictors of design performance aided by the use of metaphors. Participants were administered a design task and questionnaires about the Dimensional Profiles of Dwellings, Pathways, and Metaphors, based on the meaning system. Factors based on the factor analyses of the responses to the three questionnaires were used in regression analyses as predictors of the performance score in a design task. The following three factors of the dimensional meaning profiles of metaphors were significant predictors of design performance: sensory, functional, and structural evaluations. Implications for design education are discussed, primarily concerning the important role of metaphor in design problem-solving.

The Display of Visual Information in Mission Command Systems: Implications for Cognitive Performance in the Command Post of the Future

DTIC Science & Technology

2013-08-01

position unless so designated by other authorized documents. Citation of manufacturer’s or trade names does not constitute an official endorsement or...the presence of large volumes of time critical information. CPOF was designed to support the Army transformation to network-enabled operations. The...Cognitive Performance The visual display of information is vital to cognitive performance. For example, the poor visual design of the radar display

A Cognitive Task Analysis, with Implications for Designing a Simulation-Based Performance Assessment.

ERIC Educational Resources Information Center

Mislevy, Robert J.; Steinberg, Linda S.; Breyer, F. Jay; Almond, Russell G.; Johnson, Lynn

To function effectively as a learning environment, a simulation system must present learners with situations in which they use relevant knowledge, skills, and abilities. To function effectively as an assessment, such a system must additionally be able to evoke and interpret observable evidence about targeted knowledge in a manner that is…

Implications of sampling design and sample size for national carbon accounting systems

Treesearch

Michael Köhl; Andrew Lister; Charles T. Scott; Thomas Baldauf; Daniel Plugge

2011-01-01

Countries willing to adopt a REDD regime need to establish a national Measurement, Reporting and Verification (MRV) system that provides information on forest carbon stocks and carbon stock changes. Due to the extensive areas covered by forests the information is generally obtained by sample based surveys. Most operational sampling approaches utilize a combination of...

Third Party Payments: Alternative Funding Sources for Drug Abuse Treatment Programs. Trainer's Manual and Trainee's Handbook.

ERIC Educational Resources Information Center

Priesman, Ira

This set of materials is designed to provide helping professionals with sufficient understanding of third-party payment systems so they are able to determine the feasibility of obtaining reimbursement for service, identify potential third-party payers, assess implications of introducing a third-party payments system, and develop a plan for…

Systematically Evaluating the Effectiveness of an Information Systems Capstone Course: Implications for Practice

ERIC Educational Resources Information Center

Gill, T. Grandon; Ritzhaupt, Albert D.

2013-01-01

The information systems capstone experience for undergraduate majors is a topic frequently discussed in academic circles within the field. Though very little consensus exists on this topic, there are core themes that emerge in the design, development, and delivery of the undergraduate capstone courses. Our analysis of prior literature reveals four…

Volume of Courses Students Carry among Central Data Warehouse (CDW) Institutions: Implications for Recalibration of the BC Transfer System

ERIC Educational Resources Information Center

Box, Dale

2008-01-01

The British Columbia (BC) Council on Admissions and Transfer (BCCAT) has undertaken, in the last couple of years, a review of the BC Transfer System. Preliminary findings indicate that the current structure of the BC Transfer Guide (BCTG), which designates institutions as either "sending" institutions or "receiving"…

Toward an Ontological Approach in Goal-Oriented Language Courseware Design and Its Implications for Technology-Independent Content Structuring

ERIC Educational Resources Information Center

Colpaert, Jozef

2006-01-01

The term "design" is being understood more and more as a methodological process, together with its acceptance as the result of such a process. As a process, it is a stage in the courseware engineering life cycle which primarily focuses on rendering the development process more effective and on enhancing the qualities of the finished system,…

Improving Quality for Child Care Centers in Greater Philadelphia: An Evaluation of Success by 6®. Program Design Appendix. Publication #2016-07C

ERIC Educational Resources Information Center

Warner-Richter, Mallory; Lowe, Claire; Tout, Kathryn; Epstein, Dale; Li, Weilin

2016-01-01

The Success By 6® (SB6) initiative is designed to support early care and education centers in improving and sustaining quality in Pennsylvania's Keystone STARS Quality Rating and Improvement System (QRIS). The SB6 evaluation report examines implementation and outcomes. The findings have implications for SB6 continous quality improvement process…

Educational Systems Design Implications of Electronic Publishing.

ERIC Educational Resources Information Center

Romiszowski, Alexander J.

1994-01-01

Discussion of electronic publishing focuses on the four main purposes of media in general: communication, entertainment, motivation, and education. Highlights include electronic journals and books; hypertext; user control; computer graphics and animation; electronic games; virtual reality; multimedia; electronic performance support;…

Advanced EVA system design requirements study: EVAS/space station system interface requirements

NASA Technical Reports Server (NTRS)

Woods, T. G.

1985-01-01

The definition of the Extravehicular Activity (EVA) systems interface requirements and accomodations for effective integration of a production EVA capability into the space station are contained. A description of the EVA systems for which the space station must provide the various interfaces and accomodations are provided. The discussion and analyses of the various space station areas in which the EVA interfaces are required and/or from which implications for EVA system design requirements are derived, are included. The rationale is provided for all EVAS mechanical, fluid, electrical, communications, and data system interfaces as well as exterior and interior requirements necessary to facilitate EVA operations. Results of the studies supporting these discussions are presented in the appendix.

Design of a fast Mars space transfer system

NASA Astrophysics Data System (ADS)

Woo, Henry H.; Glass, James F.; Roy, Claude

1992-02-01

Architecture strategies and concepts for manned missions to Mars are being developed by NASA and industry. This paper addresses the key Mars transfer vehicle (MTV) design requirements which include surface payload mass, MTV mass, propulsion system characteristics, launch vehicle capability, in-space operations, abort considerations, crew exposure to interplanetary environments, and crew reconditioning for planetary entry. Different mission strategies are presented along with their implications. A representative artificial-g MTV using nuclear thermal propulsion is defined to show concepts which minimize extravehicular activity operations for in-space assembly, inspection, and maintenance.

Affordability Engineering: Bridging the Gap Between Design and Cost

NASA Technical Reports Server (NTRS)

Reeves, J. D.; DePasquale, Dominic; Lim, Evan

2010-01-01

Affordability is a commonly used term that takes on numerous meanings depending on the context used. Within conceptual design of complex systems, the term generally implies comparisons between expected costs and expected resources. This characterization is largely correct, but does not convey the many nuances and considerations that are frequently misunderstood and underappreciated. In the most fundamental sense, affordability and cost directly relate to engineering and programmatic decisions made throughout development programs. Systems engineering texts point out that there is a temporal aspect to this relationship, for decisions made earlier in a program dictate design implications much more so than those made during latter phases. This paper explores affordability engineering and its many sub-disciplines by discussing how it can be considered an additional engineering discipline to be balanced throughout the systems engineering and systems analysis processes. Example methods of multidisciplinary design analysis with affordability as a key driver will be discussed, as will example methods of data visualization, probabilistic analysis, and other ways of relating design decisions to affordability results.

Reform at a Crossroads: A Call for Balanced Systems of Assessment and Accountability. The Report of the NASBE Study Group on Assessment Systems for the 21st Century Learner

ERIC Educational Resources Information Center

National Association of State Boards of Education, 2009

2009-01-01

The movement to strengthen the nation's workforce by redefining what all students need to learn has profound implications for the design of state assessment systems. The confluence of events--the change in the national and international climate, acknowledgment of long-standing inequities in education opportunity and achievement, and the…

Using Co-Design to Develop a Collective Leadership Intervention for Healthcare Teams to Improve Safety Culture.

PubMed

Ward, Marie E; De Brún, Aoife; Beirne, Deirdre; Conway, Clare; Cunningham, Una; English, Alan; Fitzsimons, John; Furlong, Eileen; Kane, Yvonne; Kelly, Alan; McDonnell, Sinéad; McGinley, Sinead; Monaghan, Brenda; Myler, Ann; Nolan, Emer; O'Donovan, Róisín; O'Shea, Marie; Shuhaiber, Arwa; McAuliffe, Eilish

2018-06-05

While co-design methods are becoming more popular in healthcare; there is a gap within the peer-reviewed literature on how to do co-design in practice. This paper addresses this gap by delineating the approach taken in the co-design of a collective leadership intervention to improve healthcare team performance and patient safety culture. Over the course of six workshops healthcare staff, patient representatives and advocates, and health systems researchers collaboratively co-designed the intervention. The inputs to the process, exercises and activities that took place during the workshops and the outputs of the workshops are described. The co-design method, while challenging at times, had many benefits including grounding the intervention in the real-world experiences of healthcare teams. Implications of the method for health systems research are discussed.

Attitude control challenges for earth orbiters of the 1980's

NASA Technical Reports Server (NTRS)

Hibbard, W.

1980-01-01

Experience gained in designing attitude control systems for orbiting spacecraft of the late 1980's is related. Implications for satellite attitude control design of the guidance capabilities, rendezvous and recovery requirements, use of multiple-use spacecraft and the development of large spacecraft associated with the advent of the Space Shuttle are considered. Attention is then given to satellite attitude control requirements posed by the Tracking and Data Relay Satellite System, the Global Positioning System, the NASA End-to-End Data System, and Shuttle-associated subsatellites. The anticipated completion and launch of the Space Telescope, which will provide one of the first experiences with the new generation of attitude control, is also pointed out.

A Constructive Reframing of Student Roles and Systems Learning in Medical Education Using a Communities of Practice Lens.

PubMed

Gonzalo, Jed D; Thompson, Britta M; Haidet, Paul; Mann, Karen; Wolpaw, Daniel R

2017-12-01

Health systems are in the midst of a transformation that is being driven by a variety of forces. This has important implications for medical educators because clinical practice environments play a key role in learning and professional development, and evolving health systems are beginning to demand that providers have "systems-ready" knowledge, attitudes, and skills. Such implications provide a clear mandate for medical schools to modify their goals and prepare physicians to practice flexibly within teams and effectively contribute to the improvement of health care delivery. In this context, the concepts of value-added medical education, authentic student roles, and health systems science are emerging as increasingly important. In this Article, the authors use a lens informed by communities of practice theory to explore these three concepts, examining the implications that the communities of practice theory has in the constructive reframing of educational practices-particularly common student roles and experiences-and charting future directions for medical education that better align with the needs of the health care system. The authors apply several key features of the communities of practice theory to current experiential roles for students, then propose a new approach to students' clinical experiences-value-added clinical systems learning roles-that provides students with opportunities to make meaningful contributions to patient care while learning health systems science at the patient and population level. Finally, the authors discuss implications for professional role formation and anticipated challenges to the design and implementation of value-added clinical systems learning roles.

Travelling wave effects in large space structures

NASA Technical Reports Server (NTRS)

Vonflotow, A.

1983-01-01

Several aspects of travelling waves in Large Space Structures(LSS) are discussed. The dynamic similarity among LSS's, electric power systems, microwave circuits and communications network is noted. The existence of time lag between actuation and response is illuminated with the aid of simple examples, and their prediction is demonstrated. To prevent echoes, communications lines have matched terminations; this idea is applied to the design of dampers of one dimensional structures. Periodic structures act as mechanical band pass filters. Implications of this behavior are examined on a simple example. It is noted that the implication is twofold; continuum models of periodic lattice structures may err considerably; on the other hand, it is possible to design favorable transmission (and resonance) characteristics into the structure.

Space station executive summary

NASA Technical Reports Server (NTRS)

1972-01-01

An executive summary of the modular space station study is presented. The subjects discussed are: (1) design characteristics, (2) experiment program, (3) operations, (4) program description, and (5) research implications. The modular space station is considered a candidate payload for the low cost shuttle transportation system.

Coupling between Metacognition and Emotions during STEM Learning with Advanced Learning Technologies: A Critical Analysis, Implications for Future Research, and Design of Learning Systems

ERIC Educational Resources Information Center

Azevedo, Roger; Mudrick, Nicholas; Taub, Michelle; Wortha, Franz

2017-01-01

Metacognition and emotions play a critical role in learners' ability to monitor and regulate their learning about 21st-century skills related to science, technology, engineering, and mathematics (STEM) content while using advanced learning technologies (ALTs; e.g., intelligent tutoring systems, serious games, hypermedia, augmented reality). In…

Everyday Expertise in Self-Management of Diabetes in the Dominican Republic: Implications for Learning and Performance Support Systems Design

ERIC Educational Resources Information Center

Reyes Paulino, Lisette G.

2012-01-01

An epidemic such as diabetes is an extremely complex public health, economic and social problem that is difficult to solve through medical expertise alone. Evidence-based models for improving healthcare delivery systems advocate educating patients to become more active participants in their own care. This shift demands preparing chronically ill…

Intertwining Implicit and Explicit Awareness of Wellbeing to Support Peace of Mind and Connectedness

NASA Astrophysics Data System (ADS)

Dadlani, Pavan; Markopoulos, Panos; Aarts, Emile

An awareness system was designed to provide peace of mind and a sense of connectedness to adults who care for an elderly parent living alone. Our empirical research, including a field trial of six months, confirms the potential of awareness systems to support both generations suggesting that future research should examine, firstly, how to convey long-term trends regarding the wellbeing of the elderly and, secondly, how to intertwine the communication of awareness information with expressive forms of communication. We discuss implications of our studies for the design of ambient intelligent systems supporting awareness between elderly and their adult children.

Pilot's Automated Weather Support System (PAWSS) concepts demonstration project. Phase 1: Pilot's weather information requirements and implications for weather data systems design

NASA Technical Reports Server (NTRS)

Crabill, Norman L.; Dash, Ernie R.

1991-01-01

The weather information requirements for pilots and the deficiencies of the current aviation weather support system in meeting these requirements are defined. As the amount of data available to pilots increases significantly in the near future, expert system technology will be needed to assist pilots in assimilating that information. Some other desirable characteristics of an automation-assisted system for weather data acquisition, dissemination, and assimilation are also described.

Coproduction of healthcare service

PubMed Central

Batalden, Maren; Batalden, Paul; Margolis, Peter; Seid, Michael; Armstrong, Gail; Opipari-Arrigan, Lisa; Hartung, Hans

2016-01-01

Efforts to ensure effective participation of patients in healthcare are called by many names—patient centredness, patient engagement, patient experience. Improvement initiatives in this domain often resemble the efforts of manufacturers to engage consumers in designing and marketing products. Services, however, are fundamentally different than products; unlike goods, services are always ‘coproduced’. Failure to recognise this unique character of a service and its implications may limit our success in partnering with patients to improve health care. We trace a partial history of the coproduction concept, present a model of healthcare service coproduction and explore its application as a design principle in three healthcare service delivery innovations. We use the principle to examine the roles, relationships and aims of this interdependent work. We explore the principle's implications and challenges for health professional development, for service delivery system design and for understanding and measuring benefit in healthcare services. PMID:26376674

Reference Standards, Judges, and Comparison Subjects

PubMed Central

Hripcsak, George; Wilcox, Adam

2002-01-01

Medical informatics systems are often designed to perform at the level of human experts. Evaluation of the performance of these systems is often constrained by lack of reference standards, either because the appropriate response is not known or because no simple appropriate response exists. Even when performance can be assessed, it is not always clear whether the performance is sufficient or reasonable. These challenges can be addressed if an evaluator enlists the help of clinical domain experts. 1) The experts can carry out the same tasks as the system, and then their responses can be combined to generate a reference standard. 2)The experts can judge the appropriateness of system output directly. 3) The experts can serve as comparison subjects with which the system can be compared. These are separate roles that have different implications for study design, metrics, and issues of reliability and validity. Diagrams help delineate the roles of experts in complex study designs. PMID:11751799

Multi-method laboratory user evaluation of an actionable clinical performance information system: Implications for usability and patient safety.

PubMed

Brown, Benjamin; Balatsoukas, Panos; Williams, Richard; Sperrin, Matthew; Buchan, Iain

2018-01-01

Electronic audit and feedback (e-A&F) systems are used worldwide for care quality improvement. They measure health professionals' performance against clinical guidelines, and some systems suggest improvement actions. However, little is known about optimal interface designs for e-A&F, in particular how to present suggested actions for improvement. We developed a novel theory-informed system for primary care (the Performance Improvement plaN GeneratoR; PINGR) that covers the four principal interface components: clinical performance summaries; patient lists; detailed patient-level information; and suggested actions. As far as we are aware, this is the first report of an e-A&F system with all four interface components. (1) Use a combination of quantitative and qualitative methods to evaluate the usability of PINGR with target end-users; (2) refine existing design recommendations for e-A&F systems; (3) determine the implications of these recommendations for patient safety. We recruited seven primary care physicians to perform seven tasks with PINGR, during which we measured on-screen behaviour and eye movements. Participants subsequently completed usability questionnaires, and were interviewed in-depth. Data were integrated to: gain a more complete understanding of usability issues; enhance and explain each other's findings; and triangulate results to increase validity. Participants committed a median of 10 errors (range 8-21) when using PINGR's interface, and completed a median of five out of seven tasks (range 4-7). Errors violated six usability heuristics: clear response options; perceptual grouping and data relationships; representational formats; unambiguous description; visually distinct screens for confusable items; and workflow integration. Eye movement analysis revealed the integration of components largely supported effective user workflow, although the modular design of clinical performance summaries unnecessarily increased cognitive load. Interviews and questionnaires revealed PINGR is user-friendly, and that improved information prioritisation could further promote useful user action. Comparing our results with the wider usability literature we refine a previously published set of interface design recommendations for e-A&F. The implications for patient safety are significant regarding: user engagement; actionability; and information prioritisation. Our results also support adopting multi-method approaches in usability studies to maximise issue discovery and the credibility of findings. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

Issues, concerns, and initial implementation results for space based telerobotic control

NASA Technical Reports Server (NTRS)

Lawrence, D. A.; Chapel, J. D.; Depkovich, T. M.

1987-01-01

Telerobotic control for space based assembly and servicing tasks presents many problems in system design. Traditional force reflection teleoperation schemes are not well suited to this application, and the approaches to compliance control via computer algorithms have yet to see significant testing and comparison. These observations are discussed in detail, as well as the concerns they raise for imminent design and testing of space robotic systems. As an example of the detailed technical work yet to be done before such systems can be specified, a particular approach to providing manipulator compliance is examined experimentally and through modeling and analysis. This yields some initial insight into the limitations and design trade-offs for this class of manipulator control schemes. Implications of this investigation for space based telerobots are discussed in detail.

An Exponential Teaching Model for Educational Cablevision with Implications for an Advanced Degree Program in Applied Learning Systems

ERIC Educational Resources Information Center

Zink, J.

1976-01-01

The design and implementation of a cablevision delivered course on Grand Opera is described. The unique aspect of this project is that both the viewers and the production teams experienced active learning situations. (Author)

Lunar rover vehicle - an implication for rehabilitation

NASA Technical Reports Server (NTRS)

Mcfarland, S. R.; Primeauk, G. R.

1975-01-01

The feasibility of adapting the lunar roving vehicle control concept to automobiles and vans for quadriplegics was investigated. Topics discussed include the current state of automobile handicapped controls, a description of the affected population, and a design for interfacing the control system into a passenger vehice.

Meeting patient expectations: healthcare professionals and service re-engineering.

PubMed

Laing, Angus

2002-08-01

A central theme underpinning the reform of healthcare systems in western economies since the 1980s has been the emphasis on reorienting service provision around the patient. Healthcare organizations have been forced to re-appraise the design of the service delivery process, specifically the service encounter, to take account of these changing patient expectations. This reorientation of healthcare services around the patient has fundamental implications for healthcare professionals, specifically challenging the dominance of service professionals in the design and delivery of health services. Utilizing a qualitative methodological framework, this paper explores the responses of healthcare professionals to service redesign initiatives implemented in acute NHS hospitals in Scotland and considers the implications of such professional responses for the development of patient-focused service delivery. Within this, it specifically examines evolving professional perspectives on the place of a service user focus in a publicly funded healthcare system, professional attitudes towards private sector managerial practices, and the dynamics of changing professional behaviour.

Development of a knowledge management system for complex domains.

PubMed

Perott, André; Schader, Nils; Bruder, Ralph; Leonhardt, Jörg

2012-01-01

Deutsche Flugsicherung GmbH, the German Air Navigation Service Provider, follows a systematic approach, called HERA, for investigating incidents. The HERA analysis shows a distinctive occurrence of incidents in German air traffic control in which the visual perception of information plays a key role. The reasons can be partially traced back to workstation design, where basic ergonomic rules and principles are not sufficiently followed by the designers in some cases. In cooperation with the Institute of Ergonomics in Darmstadt the DFS investigated possible approaches that may support designers to implement ergonomic systems. None of the currently available tools were found to be able to meet the identified user requirements holistically. Therefore it was suggested to develop an enhanced software tool called Design Process Guide. The name Design Process Guide indicates that this tool exceeds the classic functions of currently available Knowledge Management Systems. It offers "design element" based access, shows processual and content related topics, and shows the implications of certain design decisions. Furthermore, it serves as documentation, detailing why a designer made to a decision under a particular set of conditions.

Field study of communication and workload in police helicopters - Implications for AI cockpit design

NASA Technical Reports Server (NTRS)

Linde, Charlotte; Shively, Robert J.

1988-01-01

This paper reports on the work performed by civilian helicopter crews, using audio and video recordings and a variety of workload measures (heart rate and subjective ratings) obtained in a field study of public service helicopter missions. The number and frequency of communications provided a significant source of workload. This is relevant to the design of automated cockpit systems, since many designs presuppose the use of voice I/O systems. Fluency of communications (including pauses, hesitation markers, repetitions, and false starts) furnished an early indication of the effects of fatigue. Three workload measures were correlated to identify high workload segments of flight, and to suggest alternate task allocations between crew members.

System design in an evolving system-of-systems architecture and concept of operations

NASA Astrophysics Data System (ADS)

Rovekamp, Roger N., Jr.

Proposals for space exploration architectures have increased in complexity and scope. Constituent systems (e.g., rovers, habitats, in-situ resource utilization facilities, transfer vehicles, etc) must meet the needs of these architectures by performing in multiple operational environments and across multiple phases of the architecture's evolution. This thesis proposes an approach for using system-of-systems engineering principles in conjunction with system design methods (e.g., Multi-objective optimization, genetic algorithms, etc) to create system design options that perform effectively at both the system and system-of-systems levels, across multiple concepts of operations, and over multiple architectural phases. The framework is presented by way of an application problem that investigates the design of power systems within a power sharing architecture for use in a human Lunar Surface Exploration Campaign. A computer model has been developed that uses candidate power grid distribution solutions for a notional lunar base. The agent-based model utilizes virtual control agents to manage the interactions of various exploration and infrastructure agents. The philosophy behind the model is based both on lunar power supply strategies proposed in literature, as well as on the author's own approaches for power distribution strategies of future lunar bases. In addition to proposing a framework for system design, further implications of system-of-systems engineering principles are briefly explored, specifically as they relate to producing more robust cross-cultural system-of-systems architecture solutions.

Creating More Credible and Persuasive Recommender Systems: The Influence of Source Characteristics on Recommender System Evaluations

NASA Astrophysics Data System (ADS)

Yoo, Kyung-Hyan; Gretzel, Ulrike

Whether users are likely to accept the recommendations provided by a recommender system is of utmost importance to system designers and the marketers who implement them. By conceptualizing the advice seeking and giving relationship as a fundamentally social process, important avenues for understanding the persuasiveness of recommender systems open up. Specifically, research regarding the influence of source characteristics, which is abundant in the context of humanhuman relationships, can provide an important framework for identifying potential influence factors. This chapter reviews the existing literature on source characteristics in the context of human-human, human-computer, and human-recommender system interactions. It concludes that many social cues that have been identified as influential in other contexts have yet to be implemented and tested with respect to recommender systems. Implications for recommender system research and design are discussed.

Practical tolerancing and performance implications for XUV projection lithography reduction systems (Poster Paper)

NASA Astrophysics Data System (ADS)

Viswanathan, Vriddhachalam K.

1992-07-01

Practical considerations that will strongly affect the imaging capabilities of reflecting systems for extreme-ultraviolet (XUV) projection lithography include manufacturing tolerances and thermal distortion of the mirror surfaces due to absorption of a fraction of the incident radiation beam. We have analyzed the potential magnitudes of these effects for two types of reflective projection optical designs. We find that concentric, symmetric two-mirror systems are less sensitive to manufacturing errors and thermal distortion than off-axis, four-mirror systems.

Assessment of a Rotating Time Sampling Procedure: Implications for Interobserver Agreement and Response Measurement

ERIC Educational Resources Information Center

Becraft, Jessica L.; Borrero, John C.; Davis, Barbara J.; Mendres-Smith, Amber E.

2016-01-01

The current study was designed to evaluate a rotating momentary time sampling (MTS) data collection system. A rotating MTS system has been used to measure activity preferences of preschoolers but not to collect data on responses that vary in duration and frequency (e.g., talking). We collected data on talking for 10 preschoolers using a 5-s MTS…

Formative Assessment and the Design of Instructional Systems.

ERIC Educational Resources Information Center

Sadler, D. Royce

1989-01-01

Discusses the nature and function of formative assessment in the development of students' expertise for evaluating the quality of their own work. Highlights include the transition from teacher-supplied feedback to learner self-monitoring; qualitative judgments; communicating standards to students; multicriterion judgments; and implications for the…

Content Independence in Multimedia Databases.

ERIC Educational Resources Information Center

de Vries, Arjen P.

2001-01-01

Investigates the role of data management in multimedia digital libraries, and its implications for the design of database management systems. Introduces the notions of content abstraction and content independence. Proposes a blueprint of a new class of database technology, which supports the basic functionality for the management of both content…

Advanced Pedestrian Positioning System to Smartphones and Smartwatches.

PubMed

Correa, Alejandro; Munoz Diaz, Estefania; Bousdar Ahmed, Dina; Morell, Antoni; Lopez Vicario, Jose

2016-11-11

In recent years, there has been an increasing interest in the development of pedestrian navigation systems for satellite-denied scenarios. The popularization of smartphones and smartwatches is an interesting opportunity for reducing the infrastructure cost of the positioning systems. Nowadays, smartphones include inertial sensors that can be used in pedestrian dead-reckoning (PDR) algorithms for the estimation of the user's position. Both smartphones and smartwatches include WiFi capabilities allowing the computation of the received signal strength (RSS). We develop a new method for the combination of RSS measurements from two different receivers using a Gaussian mixture model. We also analyze the implication of using a WiFi network designed for communication purposes in an indoor positioning system when the designer cannot control the network configuration. In this work, we design a hybrid positioning system that combines inertial measurements, from low-cost inertial sensors embedded in a smartphone, with RSS measurements through an extended Kalman filter. The system has been validated in a real scenario, and results show that our system improves the positioning accuracy of the PDR system thanks to the use of two WiFi receivers. The designed system obtains an accuracy up to 1.4 m in a scenario of 6000 m 2 .

More than meets the eye: Using cognitive work analysis to identify design requirements for future rail level crossing systems.

PubMed

Salmon, Paul M; Lenné, Michael G; Read, Gemma J M; Mulvihill, Christine M; Cornelissen, Miranda; Walker, Guy H; Young, Kristie L; Stevens, Nicholas; Stanton, Neville A

2016-03-01

An increasing intensity of operations means that the longstanding safety issue of rail level crossings is likely to become worse in the transport systems of the future. It has been suggested that the failure to prevent collisions may be, in part, due to a lack of systems thinking during design, crash analysis, and countermeasure development. This paper presents a systems analysis of current active rail level crossing systems in Victoria, Australia that was undertaken to identify design requirements to improve safety in future rail level crossing environments. Cognitive work analysis was used to analyse rail level crossing systems using data derived from a range of activities. Overall the analysis identified a range of instances where modification or redesign in line with systems thinking could potentially improve behaviour and safety. A notable finding is that there are opportunities for redesign outside of the physical rail level crossing infrastructure, including improved data systems, in-vehicle warnings and modifications to design processes, standards and guidelines. The implications for future rail level crossing systems are discussed. Copyright © 2015 Elsevier Ltd and The Ergonomics Society. All rights reserved.

Designing a Web-Based Science Learning Environment for Model-Based Collaborative Inquiry

NASA Astrophysics Data System (ADS)

Sun, Daner; Looi, Chee-Kit

2013-02-01

The paper traces a research process in the design and development of a science learning environment called WiMVT (web-based inquirer with modeling and visualization technology). The WiMVT system is designed to help secondary school students build a sophisticated understanding of scientific conceptions, and the science inquiry process, as well as develop critical learning skills through model-based collaborative inquiry approach. It is intended to support collaborative inquiry, real-time social interaction, progressive modeling, and to provide multiple sources of scaffolding for students. We first discuss the theoretical underpinnings for synthesizing the WiMVT design framework, introduce the components and features of the system, and describe the proposed work flow of WiMVT instruction. We also elucidate our research approach that supports the development of the system. Finally, the findings of a pilot study are briefly presented to demonstrate of the potential for learning efficacy of the WiMVT implementation in science learning. Implications are drawn on how to improve the existing system, refine teaching strategies and provide feedback to researchers, designers and teachers. This pilot study informs designers like us on how to narrow the gap between the learning environment's intended design and its actual usage in the classroom.

Performance management in healthcare: a critical analysis.

PubMed

Hewko, Sarah J; Cummings, Greta G

2016-01-01

Purpose - The purpose of this paper is to explore the underlying theoretical assumptions and implications of current micro-level performance management and evaluation (PME) practices, specifically within health-care organizations. PME encompasses all activities that are designed and conducted to align employee outputs with organizational goals. Design/methodology/approach - PME, in the context of healthcare, is analyzed through the lens of critical theory. Specifically, Habermas' theory of communicative action is used to highlight some of the questions that arise in looking critically at PME. To provide a richer definition of key theoretical concepts, the authors conducted a preliminary, exploratory hermeneutic semantic analysis of the key words "performance" and "management" and of the term "performance management". Findings - Analysis reveals that existing micro-level PME systems in health-care organizations have the potential to create a workforce that is compliant, dependent, technically oriented and passive, and to support health-care systems in which inequalities and power imbalances are perpetually reinforced. Practical implications - At a time when the health-care system is under increasing pressure to provide high-quality, affordable services with fewer resources, it may be wise to investigate new sector-specific ways of evaluating and managing performance. Originality/value - In this paper, written for health-care leaders and health human resource specialists, the theoretical assumptions and implications of current PME practices within health-care organizations are explored. It is hoped that readers will be inspired to support innovative PME practices within their organizations that encourage peak performance among health-care professionals.

Co Modeling and Co Synthesis of Safety Critical Multi threaded Embedded Software for Multi Core Embedded Platforms

DTIC Science & Technology

2017-03-20

computation, Prime Implicates, Boolean Abstraction, real- time embedded software, software synthesis, correct by construction software design , model...types for time -dependent data-flow networks". J.-P. Talpin, P. Jouvelot, S. Shukla. ACM-IEEE Conference on Methods and Models for System Design ...information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing   data sources, gathering and

CVX: Propulsion System Decision. Industrial Base Implications of Nuclear and Non-Nuclear Options

DTIC Science & Technology

1998-01-01

industrial base may be affected by the demand for either a nuclear or non-nuclear CVX. If CVX were conventional, the cost of components for other...air- craft carrier, designated CVX. Because of the high cost of designing a new carrier and because of competing demands within its budget, the Navy...reactor re- fuelings. The organizations also supplied workforce requirements associated with different nuclear workload demands and the costs of

Reference standards, judges, and comparison subjects: roles for experts in evaluating system performance.

PubMed

Hripcsak, George; Wilcox, Adam

2002-01-01

Medical informatics systems are often designed to perform at the level of human experts. Evaluation of the performance of these systems is often constrained by lack of reference standards, either because the appropriate response is not known or because no simple appropriate response exists. Even when performance can be assessed, it is not always clear whether the performance is sufficient or reasonable. These challenges can be addressed if an evaluator enlists the help of clinical domain experts. 1) The experts can carry out the same tasks as the system, and then their responses can be combined to generate a reference standard. 2)The experts can judge the appropriateness of system output directly. 3) The experts can serve as comparison subjects with which the system can be compared. These are separate roles that have different implications for study design, metrics, and issues of reliability and validity. Diagrams help delineate the roles of experts in complex study designs.

Shuttle/ISS EMU Failure History and the Impact on Advanced EMU Portable Life Support System (PLSS) Design

NASA Technical Reports Server (NTRS)

Campbell, Colin

2015-01-01

As the Shuttle/ISS EMU Program exceeds 35 years in duration and is still supporting the needs of the International Space Station (ISS), a critical benefit of such a long running program with thorough documentation of system and component failures is the ability to study and learn from those failures when considering the design of the next generation space suit. Study of the subject failure history leads to changes in the Advanced EMU Portable Life Support System (PLSS) schematic, selected component technologies, as well as the planned manner of ground testing. This paper reviews the Shuttle/ISS EMU failure history and discusses the implications to the AEMU PLSS.

Socio-technical systems and interaction design - 21st century relevance.

PubMed

Maguire, Martin

2014-03-01

This paper focuses on the relationship between the socio-technical system and the user-technology interface. It looks at specific aspects of the organisational context such as multiple user roles, job change, work processes and workflows, technical infrastructure, and the challenges they present for the interaction designer. The implications of trends such as more mobile and flexible working, the use of social media, and the growth of the virtual organisation, are also considered. The paper also reviews rapidly evolving technologies such as pervasive systems and artificial intelligence, and the skills that workers will need to engage with them. Copyright © 2013 Elsevier Ltd and The Ergonomics Society. All rights reserved.

Small Business Innovations

NASA Technical Reports Server (NTRS)

1992-01-01

The purpose of QASE RT is to enable system analysts and software engineers to evaluate performance and reliability implications of design alternatives. The program resulted from two Small Business Innovation Research (SBIR) projects. After receiving a description of the system architecture and workload from the user, QASE RT translates the system description into simulation models and executes them. Simulation provides detailed performance evaluation. The results of the evaluations are service and response times, offered load and device utilizations and functional availability.

Impact of cooking and home food preparation interventions among adults: outcomes and implications for future programs

PubMed Central

Reicks, Marla; Trofholz, Amanda C.; Stang, Jamie S; Laska, Melissa N.

2014-01-01

Objective Cooking programs are growing in popularity; however an extensive review has not examined overall impact. Therefore, this study reviewed previous research on cooking/home food preparation interventions and diet and health-related outcomes among adults and identified implications for practice and research. Design Literature review and descriptive summative method. Main outcome measures Dietary intake, knowledge/skills, cooking attitudes and self-efficacy/confidence, health outcomes. Analysis Articles evaluating effectiveness of interventions that included cooking/home food preparation as the primary aim (January 1980 through December 2011) were identified via OVID MEDLINE, Agricola and Web of Science databases. Studies grouped according to design and outcomes were reviewed for validity using an established coding system. Results were summarized for several outcome categories. Results Of 28 studies identified, 12 included a control group with six as non-randomized and six as randomized controlled trials. Evaluation was done post-intervention for five studies, pre- and post-intervention for 23 and beyond post-intervention for 15. Qualitative and quantitative measures suggested a positive influence on main outcomes. However, non-rigorous study designs, varying study populations, and use of non-validated assessment tools limited stronger conclusions. Conclusions and Implications Well-designed studies are needed that rigorously evaluate long-term impact on cooking behavior, dietary intake, obesity and other health outcomes. PMID:24703245

Biological Applications of Designed Hairpin Peptides: As Antimicrobials and as Inhibitors of Amyloidogenesis

NASA Astrophysics Data System (ADS)

Sivanesam, Kalkena

More than 40 diseases have been associated with the misfolding of peptides (or proteins) that form fibrils with a very specific morphology. These peptides classified as amyloidogenic peptides have been implicated in the development of Alzheimer's Disease, Parkinson's Disease, Type II Diabetes, Hungtinton's Disease etc. To date, these diseases have no cure, only therapies that can ameliorate the symptoms to a degree. Inhibition of the amyloidogenesis of these peptides has been proposed as a possible treatment option. While small molecules have been heavily tested as inhibitors of amyloidogenesis, peptides have emerged as potential inhibitors. In this work, the ability of a set of designed hairpin peptides to inhibit the amyloidogenesis of two different systems, alpha-synuclein (implicated in Parkinson's Disease) and human amylin (implicated in Type II Diabetes) is tested. Using circular dichroism and thioflavin T fluorescence, the ability of these peptides to inhibit amyloidogenesis is tested. The binding loci of these inhibitors to alpha-synuclein are also explored. The use of peptides as antimicrobials on the other hand is not a novel concept. However, most antimicrobial peptides, both natural and designed, rely heavily on covalent stabilizations in order to maintain secondary structure. In this study, non-covalent stabilizations are applied to a couple of natural as well as designed antimicrobials in order to study the effects of secondary structure stabilization on biological activity.

The Learner-Centered Curriculum: Design and Implementation

ERIC Educational Resources Information Center

Cullen, Roxanne; Harris, Michael; Hill, Reinhold R.

2012-01-01

Most of the scholarship on learner-centeredness is focused on individual classroom pedagogy, but this book takes learner-centeredness beyond the classroom and asks academic leaders to consider the broader implications of making their institutions fully learner-centered. Systemic change is needed, and curriculum is at the heart of what higher…

Application of Cognitive Science Principles: Instructional Heuristics and Mechanisms for Use.

ERIC Educational Resources Information Center

Montague, William E.

Cognitive science is briefly reviewed, and its implications for instructional design are discussed. The application of cognitive science to instruction requires knowledge of cognitive science, the subject content taught, and the system in which the instruction is imbedded. The central concept of cognitive science is mental representation--the…

"Bearing Down" on Student Non-Completion: Implications and Consequences for English Higher Education

ERIC Educational Resources Information Center

Longden, Bernard

2013-01-01

This article traces recent policy developments relating to full-time undergraduate student retention within the English higher education system. It focuses specifically on the changing government policies and strategies designed to influence institutional behavior to promote widening participation while attending to the student experience and…

A Pirate's Life: A Model and a Metaphor for Learning.

ERIC Educational Resources Information Center

Solomon, David L.

2002-01-01

Discusses various ways in which context may be interpreted to enhance learning and performance; illustrates domains of learning using a hockey team as an example; and suggests implications for learning, performance, and instructional design. Highlights include an ecological systems model; and examples of individual development, team learning, and…

School Finance Adequacy: What Is It and How Do We Measure It?

ERIC Educational Resources Information Center

Picus, Lawrence O.

2001-01-01

Discusses legal definition of school-finance "adequacy" and four methods for determining the cost of an adequate system: Cost function, observational methods, professional judgment, and costs of a comprehensive school design. Draws implications for school districts' resource-allocation decisions based on adequacy. (Contains 21 references.) (PKP)

Getting to Know You: Discovering User Behaviors and Their Implications for Service Design

ERIC Educational Resources Information Center

Daigle, Ben

2013-01-01

Public services librarians are often in the position of training patrons how to use technology. They adopt new technologies such as discovery layers, link resolvers, subject guides, virtual reference services, OPACs, content management systems, and institutional repositories to provide access to materials and facilitate collaboration, but…

Curriculum Theory, Curriculum Policy and the Problem of Ill-Disciplined Thinking

ERIC Educational Resources Information Center

Harris, Richard; Burn, Katharine

2011-01-01

This paper examines the implications of policy fracture and arms length governance within the decision-making processes currently shaping curriculum design within the English education system. In particular, it argues that an unresolved "ideological fracture" at the government level has been passed down to school leaders whose response…

The Implications of a System-Wide Positive Behavioral Intervention Initiative: From Design to Successful Implementation

ERIC Educational Resources Information Center

Austin, Vance L.; Malow, Micheline S.; Josephs, Nikki L.; Ecker, Andrew J.

2016-01-01

Residential schools for students with emotional and behavioral disorders have been steadily evolving since the beginning of the 20th Century. Traditional behavioral approaches involving physical restraint and confinement have been replaced with more humanistic interventions involving positive reinforcement. This article traces this transformative…

Globalization of Access to Higher Education: Lessons for Nigeria

ERIC Educational Resources Information Center

Uchendu, C. C.

2013-01-01

Education is such a powerful instrument for national transformation and development such that anything that affects an educational system negatively affects the national development. This study investigated the extent to which access to higher education is globalized and the implications for Nigeria. An ex-post facto research design was adopted…

Mainstreaming Handicapped Preschoolers. Proceedings of a Topical Workshop. TADscripts '82.

ERIC Educational Resources Information Center

Anderson, Joan; Black, Talbot

The document offers proceedings from a Technical Assistance Development System (TADS) topical workshop designed to explore the implications of mainstreaming for early childhood education. The first section contains an adaptation of the keynote address by A. Turnbull titled "Integration of Handicapped Children in Home, School, and…

Trends in Classroom Observation Scores

ERIC Educational Resources Information Center

Casabianca, Jodi M.; Lockwood, J. R.; McCaffrey, Daniel F.

2015-01-01

Observations and ratings of classroom teaching and interactions collected over time are susceptible to trends in both the quality of instruction and rater behavior. These trends have potential implications for inferences about teaching and for study design. We use scores on the Classroom Assessment Scoring System-Secondary (CLASS-S) protocol from…

Restructuring the Guidance Delivery System: Implications for High School Counselors.

ERIC Educational Resources Information Center

Greer, Richard M.; Richardson, Michael D.

1992-01-01

Notes that large portion of high school counselor's clientele, working parents, are not available during regular school hours. Suggests model program using flexible scheduling for high school counselors designed to address the issues of a changing clientele, a changing society, and changing expectation of counselors and schools. (NB)

Tradable credits system design and cost savings for a national low carbon fuel standard for road transport

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rubin, Jonathan; Leiby, Paul N.

2012-06-11

This research examines the economic implications of different designs for a national low carbon fuel standard (NLCFS) for the road transportation sector. A NLCFS based on the average Carbon Intensity (CI) of all fuels sold in the gasoline and diesel markets will generate an incentive for fuel suppliers to reduce the measured CI of their petroleum fuels. The economic impacts of a NLCFS are fundamentally determined by: the availability of low carbon fuels; the compliance path; the reference level CI of the fuel baseline; and the degree of flexibility in the credit system. To quantitatively examine the implications of amore » NLCFS, we created the Transportation Regulation and Credit Trading (TRACT) Model. With TRACT, we model a NLCFS credit trading system among profit maximizing fuel suppliers for light- and heavy-duty vehicle fuel use for the United States from 2012 - 2030. Given the wide range of cost and availability of biofuels, we find that credit trading across gasoline and diesel fuel markets combined with credit banking can significantly reduce compliance costs and stabilize credit prices. We make policy recommendations on how to combine a NLCFS with other existing regulations for transportation fuels.« less

Enhancing Collaborative Learning in Web 2.0-Based E-Learning Systems: A Design Framework for Building Collaborative E-Learning Contents

ERIC Educational Resources Information Center

El Mhouti, Abderrahim; Nasseh, Azeddine; Erradi, Mohamed; Vasquèz, José Marfa

2017-01-01

Today, the implication of Web 2.0 technologies in e-learning allows envisaging new teaching and learning forms, advocating an important place to the collaboration and social interaction. However, in e-learning systems, learn in a collaborative way is not always so easy because one of the difficulties when arranging e-learning courses can be that…

Interfacing theories of program with theories of evaluation for advancing evaluation practice: Reductionism, systems thinking, and pragmatic synthesis.

PubMed

Chen, Huey T

2016-12-01

Theories of program and theories of evaluation form the foundation of program evaluation theories. Theories of program reflect assumptions on how to conceptualize an intervention program for evaluation purposes, while theories of evaluation reflect assumptions on how to design useful evaluation. These two types of theories are related, but often discussed separately. This paper attempts to use three theoretical perspectives (reductionism, systems thinking, and pragmatic synthesis) to interface them and discuss the implications for evaluation practice. Reductionism proposes that an intervention program can be broken into crucial components for rigorous analyses; systems thinking view an intervention program as dynamic and complex, requiring a holistic examination. In spite of their contributions, reductionism and systems thinking represent the extreme ends of a theoretical spectrum; many real-world programs, however, may fall in the middle. Pragmatic synthesis is being developed to serve these moderate- complexity programs. These three theoretical perspectives have their own strengths and challenges. Knowledge on these three perspectives and their evaluation implications can provide a better guide for designing fruitful evaluations, improving the quality of evaluation practice, informing potential areas for developing cutting-edge evaluation approaches, and contributing to advancing program evaluation toward a mature applied science. Copyright © 2016 Elsevier Ltd. All rights reserved.

Changing Perceptions of Flooding and Stormwater as a Driver of Urban Hydrology and Biogeochemistry

NASA Astrophysics Data System (ADS)

Hale, R. L.

2015-12-01

Urbanization can have detrimental impacts on downstream ecosystems due to its effects on hydrological and biogeochemical cycles. In particular, how urban stormwater systems are designed have implications for flood regimes and biogeochemical transformations. Flood and stormwater management paradigms have shifted over time at large scales, but patterns and drivers of local stormwater infrastructure designs are unknown. We describe patterns of infrastructure design and use over the 20th century in three cities along an urbanization gradient in Utah: Salt Lake, Logan, and Heber City. To understand changes in stormwater management paradigms we conducted a historical media content analysis of newspaper articles related to flooding and stormwater in Salt Lake City from 1900 to 2012. Stormwater infrastructure design varied spatially and temporally, both within and among cities. All three cities transitioned from agriculture to urban land use, and legacies were evident in the use of agricultural canals for stormwater conveyance. Salt Lake City infrastructure transitioned from centralized storm sewers during early urbanization to decentralized detention systems in the 1970's. In contrast, newer cities, Logan and Heber, saw parallel increases in conveyance and detention systems with urbanization. The media analysis revealed significant changes in flood and stormwater management paradigms over the 20th century that were driven by complex factors including top-down regulations, local disturbances, and funding constraints. Early management paradigms focused on infrastructural solutions to address problems with private and public property damage, whereas more recent paradigms focus on behavioral solutions to flooding and green infrastructure solutions to prevent negative impacts of urban stormwater on local ecosystems. Changes in human perceptions of the environment can affect how we design urban ecosystems, with important implications for ecological functions.

Quantifying and minimizing entropy generation in AMTEC cells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hendricks, T.J.; Huang, C.

1997-12-31

Entropy generation in an AMTEC cell represents inherent power loss to the AMTEC cell. Minimizing cell entropy generation directly maximizes cell power generation and efficiency. An internal project is on-going at AMPS to identify, quantify and minimize entropy generation mechanisms within an AMTEC cell, with the goal of determining cost-effective design approaches for maximizing AMTEC cell power generation. Various entropy generation mechanisms have been identified and quantified. The project has investigated several cell design techniques in a solar-driven AMTEC system to minimize cell entropy generation and produce maximum power cell designs. In many cases, various sources of entropy generation aremore » interrelated such that minimizing entropy generation requires cell and system design optimization. Some of the tradeoffs between various entropy generation mechanisms are quantified and explained and their implications on cell design are discussed. The relationship between AMTEC cell power and efficiency and entropy generation is presented and discussed.« less

Propulsion System Choices and Their Implications

NASA Technical Reports Server (NTRS)

Joyner, Claude R., II; Levack, Daniel J. H.; Rhodes, Russell, E.; Robinson, John W.

2010-01-01

In defining a space vehicle architecture, the propulsion system and related subsystem choices will have a major influence on achieving the goals and objectives desired. There are many alternatives and the choices made must produce a system that meets the performance requirements, but at the same time also provide the greatest opportunity of reaching all of the required objectives. Recognizing the above, the SPST Functional Requirements subteam has drawn on the knowledge, expertise, and experience of its members, to develop insight that wiIJ effectively aid the architectural concept developer in making the appropriate choices consistent with the architecture goals. This data not only identifies many selected choices, but also, more importantly, presents the collective assessment of this subteam on the "pros" and the "cons" of these choices. The propulsion system choices with their pros and cons are presented in five major groups. A. System Integration Approach. Focused on the requirement for safety, reliability, dependability, maintainability, and low cost. B. Non-Chemical Propulsion. Focused on choice of propulsion type. C. Chemical Propulsion. Focused on propellant choice implications. D. Functional Integration. Focused on the degree of integration of the many propulsive and closely associated functions, and on the choice of the engine combustion power cycle. E. Thermal Management. Focused on propellant tank insulation and integration. Each of these groups is further broken down into subgroups, and at that level the consensus pros and cons are presented. The intended use of this paper is to provide a resource of focused material for architectural concept developers to use in designing new advanced systems including college design classes. It is also a possible source of input material for developing a model for designing and analyzing advanced concepts to help identify focused technology needs and their priorities.

Homeward Bound: Ecological Design of Domestic Information Systems

NASA Astrophysics Data System (ADS)

Wastell, David G.; Sauer, Juergen S.; Schmeink, Claudia

Information technology artefacts are steadily permeating everyday life, just as they have colonized the business domain. Although research in our field has largely addressed the workplace, researchers are beginning to take an interest in the home environment too. Here, we address the domestic realm, focusing on the design of complex, interactive information systems. As such, our work sits in the design science version rather than behavioral science paradigm of IS research. We argue that the home is in many ways a more challenging environment for the designer than the workplace, making good design of critical importance. Regrettably, the opposite would appear to be the norm. Two experiments are reported, both concerned with the design of the user interface for domestic heating systems. Of note is our use of a medium-fidelity laboratory simulation or "microworld" in this work. Two main substantive findings resulted. First, that ecologically designed feedback, embodying a strong mapping between task goals and system status, produced superior task performance. Second, that predictive decision aids provided clear benefits over other forms of user support, such as advisory systems. General implications for the design of domestic information systems are discussed, followed by reflections on the nature of design work in IS, and on the design science project itself. It is concluded that the microworld approach has considerable potential for developing IS design theory. The methodological challenges of design research are highlighted, especially the presence of additional validity threats posed by the need to construct artefacts in order to evaluate theory. It is argued that design theory is necessarily complex, modal, and uncertain, and that design science (like design itself) should be prosecuted in an open, heuristic spirit, drawing more on the proven methods of "good design" (e.g.,prototyping, user participation) in terms of its own praxis.

Live fire testing requirements - Assessing the impact

DOE Office of Scientific and Technical Information (OSTI.GOV)

O'Bryon, J.F.

1992-08-01

Full-up live-fire testing (LFT) of aircraft configured for combat is evaluated in terms of the practical implications of the technique. LFT legislation requires the testing of tactical fighters, helicopters, and other aircraft when they are loaded with the flammables and explosives associated with combat. LFT permits the study of damage mechanisms and battle-damage repair techniques during the design phase, and probability-of-kill estimates and novel systems designs can be developed based on LFT data.

Multidisciplinary Design Optimization Techniques: Implications and Opportunities for Fluid Dynamics Research

NASA Technical Reports Server (NTRS)

Zang, Thomas A.; Green, Lawrence L.

1999-01-01

A challenge for the fluid dynamics community is to adapt to and exploit the trend towards greater multidisciplinary focus in research and technology. The past decade has witnessed substantial growth in the research field of Multidisciplinary Design Optimization (MDO). MDO is a methodology for the design of complex engineering systems and subsystems that coherently exploits the synergism of mutually interacting phenomena. As evidenced by the papers, which appear in the biannual AIAA/USAF/NASA/ISSMO Symposia on Multidisciplinary Analysis and Optimization, the MDO technical community focuses on vehicle and system design issues. This paper provides an overview of the MDO technology field from a fluid dynamics perspective, giving emphasis to suggestions of specific applications of recent MDO technologies that can enhance fluid dynamics research itself across the spectrum, from basic flow physics to full configuration aerodynamics.

Coal conversion systems design and process modeling. Volume 2: Installation of MPPM on the Signal 9 computer

NASA Technical Reports Server (NTRS)

1981-01-01

Relevant differences between the MPPM resident IBM 370computer and the NASA Sigma 9 computer are described as well as the MPPM system itself and its development. Problems encountered and solutions used to overcome these difficulties during installation of the MPPM system at MSFC are discussed. Remaining work on the installation effort is summarized. The relevant hardware features incorporated in the program are described and their implications on the transportability of the MPPM source code are examined.

Selected Foreign Counterparts of U.S. Army Ground Combat Systems and Implications for Combat Operations and Modernization

DTIC Science & Technology

2017-01-18

System program. 7 While it may not be realistic to have definitive design criteria for a vehicle to be fielded in 2035 established now, a clearer...is focused on fielding an existing “hard kill” APS capability in the near term for the Army’s M-1 Abrams tanks, M-2/3 Bradley fighting vehicles , and...infantry fighting vehicles (IFVs), tracked self-propelled (SP) artillery, and multiple launch rocket systems (MLRS), which constitutes the nucleus

Using Knowledge-Based Systems to Support Learning of Organizational Knowledge: A Case Study

NASA Technical Reports Server (NTRS)

Cooper, Lynne P.; Nash, Rebecca L.; Phan, Tu-Anh T.; Bailey, Teresa R.

2003-01-01

This paper describes the deployment of a knowledge system to support learning of organizational knowledge at the Jet Propulsion Laboratory (JPL), a US national research laboratory whose mission is planetary exploration and to 'do what no one has done before.' Data collected over 19 weeks of operation were used to assess system performance with respect to design considerations, participation, effectiveness of communication mechanisms, and individual-based learning. These results are discussed in the context of organizational learning research and implications for practice.

Coproduction of healthcare service.

PubMed

Batalden, Maren; Batalden, Paul; Margolis, Peter; Seid, Michael; Armstrong, Gail; Opipari-Arrigan, Lisa; Hartung, Hans

2016-07-01

Efforts to ensure effective participation of patients in healthcare are called by many names-patient centredness, patient engagement, patient experience. Improvement initiatives in this domain often resemble the efforts of manufacturers to engage consumers in designing and marketing products. Services, however, are fundamentally different than products; unlike goods, services are always 'coproduced'. Failure to recognise this unique character of a service and its implications may limit our success in partnering with patients to improve health care. We trace a partial history of the coproduction concept, present a model of healthcare service coproduction and explore its application as a design principle in three healthcare service delivery innovations. We use the principle to examine the roles, relationships and aims of this interdependent work. We explore the principle's implications and challenges for health professional development, for service delivery system design and for understanding and measuring benefit in healthcare services. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Investigation of short cavity CRDS noise terms by optical correlation

NASA Astrophysics Data System (ADS)

Griffin, Steven T.; Fathi, Jason

2013-05-01

Cavity Ring Down Spectroscopy (CRDS) has been identified as having significant potential for Department of Defense security and sensing applications. Significant factors in the development of new sensor architectures are portability, robustness and economy. A significant factor in new CRDS sensor architectures is cavity length. Prior publication has examined the role of cavity length in sensing modality both from the standpoint of the system's design and the identification of potential difficulties presented by novel approaches. Two of interest here are new noise terms that have been designated turbulence-like and speckle-like in prior publication. In the prior publication the theoretical and some empirical data was presented. This presentation addresses the automation of the experimental apparatus, new data analysis, and implications regarding the significance of the two noise terms. This is accomplished through an Analog-to- Digital Conversion (ADC) from the output of a custom designed optical correlator. Details of the unique application of the developed instrument and implications for short cavity (portable) CRDS applications are presented.

The Invisible Work of Being a Patient and Implications for Health Care: “[the doctor is] my business partner in the most important business in my life, staying alive”

PubMed Central

UNRUH, KENTON T.; PRATT, WANDA

2010-01-01

In a distributed system of care, patients shuffle among many clinicians and spend the majority of their time away from the treatment center. Although we see the results of patients’ work (e.g., medication taken, arrived at appointment) we do not see the work itself. By failing to see this work, industry overlooks issues with vital implications for their business. To lift the veil of invisibility from patients’ work, we conducted a longitudinal field study to uncover the invisible work breast cancer patients do to obtain information, bridge inter-institutional care, manage dependencies and resolve inconsistent recommendations. In this paper we provide detailed examples of this work and explore the impact on patients and health-care operations; identify patterns of work with implications for patient-centered research and design; and propose common information spaces to improve patients’ work through designs that highlight dependencies, preserve state information, link recommendations to justifications, and track task progress. PMID:21709742

Design Considerations of a Solid State Thermal Energy Storage

NASA Astrophysics Data System (ADS)

Janbozorgi, Mohammad; Houssainy, Sammy; Thacker, Ariana; Ip, Peggy; Ismail, Walid; Kavehpour, Pirouz

2016-11-01

With the growing governmental restrictions on carbon emission, renewable energies are becoming more prevalent. A reliable use of a renewable source however requires a built-in storage to overcome the inherent intermittent nature of the available energy. Thermal design of a solid state energy storage has been investigated for optimal performance. The impact of flow regime, laminar vs. turbulent, on the design and sizing of the system is also studied. The implications of low thermal conductivity of the storage material are discussed and a design that maximizes the round trip efficiency is presented. This study was supported by Award No. EPC-14-027 Granted by California Energy Commission (CEC).

Private investment in hospitals: a comparison of three healthcare systems and possible implications for real estate strategies.

PubMed

van der Zwart, Johan; van der Voordt, Theo; Jonge, Hans de

2010-01-01

This article explores lessons to be learned from three different healthcare systems and the possible implications for the management of healthcare real estate, in particular in connection to the Dutch system. It discusses similarities and differences among the different systems, in search of possible consequences on cost, financing, and design innovation. To keep healthcare affordable in the future, the Dutch government is currently in the process of changing legislation to move from a centrally directed system to a so-called regulated market system. The deregulation of real estate investment that accompanies the new healthcare delivery system offers healthcare organizations new opportunities, but also more responsibility and greater risk in return on investment. Consequently, healthcare organizations must find new methods of financing. Private investment is one of the options. Three healthcare systems were analyzed on the basis of a literature review and document analysis, then schematized to show similarities and dissimilarities with regard to private investment in hospitals. Observations are based on a selection of recently published articles on private-sector financing and its implications for healthcare real estate decision making in the Netherlands, the United Kingdom, and Germany. The strengths and weaknesses of three healthcare systems with differing proportions of private and public investment in hospitals were explored. Research revealed a gap between intended effects and actual effects with regard to quality and cost. Costly private finance does not necessarily lead to "value for money." Transferring real estate decisions to private investors decreases the influence of the healthcare organization on future costs and quality. The three healthcare systems show substantial differences between public and private responsibilities. Less governmental involvement affords both opportunities and risks for hospitals. Private investment may lead to innovation, improved efficiency, and cost reduction, provided that the costs and benefits of decisions are not separated between different stakeholders. A missing link between infrastructure provision and healthcare delivery may impede design innovation and optimal adaptation to work processes and could lead to an inefficient allocation of risks and benefits.

Haptic Glove Technology: Skill Development through Video Game Play

ERIC Educational Resources Information Center

Bargerhuff, Mary Ellen; Cowan, Heidi; Oliveira, Francisco; Quek, Francis; Fang, Bing

2010-01-01

This article introduces a recently developed haptic glove system and describes how the participants used a video game that was purposely designed to train them in skills that are needed for the efficient use of the haptic glove. Assessed skills included speed, efficiency, embodied skill, and engagement. The findings and implications for future…

"To Give an Example Is a Complex Act": Agamben's Pedagogy of the Paradigm

ERIC Educational Resources Information Center

Meskin, Jacob; Shapiro, Harvey

2014-01-01

Agamben's notion of the "paradigm" has far-reaching implications for educational thinking, curriculum design and pedagogical conduct. In his approach, examples--or paradigms--deeply engage our powers of analogy, enabling us to discern previously unseen affinities among singular objects by stepping outside established systems of…

Term Relevance Feedback and Mediated Database Searching: Implications for Information Retrieval Practice and Systems Design.

ERIC Educational Resources Information Center

Spink, Amanda

1995-01-01

This study uses the human approach to examine the sources and effectiveness of search terms selected during 40 mediated interactive database searches and focuses on determining the retrieval effectiveness of search terms identified by users and intermediaries from retrieved items during term relevance feedback. (Author/JKP)

A Framework for Defining and Assessing Occupational and Training Standards in Developing Countries. Information Series.

ERIC Educational Resources Information Center

Fretwell, David H.; Lewis, Morgan V.; Deij, Arjen

The key issues, alternatives, and implications for developing countries to consider when designing systems to define occupational standards, related training standards, and assessments were analyzed. The analysis focused on the following issues: the rationale for development of standards; clarification of definitions, terminology, and assumptions;…

A Detailed Analysis of End-User Search Behaviors.

ERIC Educational Resources Information Center

Wildemuth, Barbara M.; And Others

1991-01-01

Discussion of search strategy formulation focuses on a study at the University of North Carolina at Chapel Hill that analyzed how medical students developed and revised search strategies for microbiology database searches. Implications for future research on search behavior, for system interface design, and for end user training are suggested. (16…

Multiple Knowledges for Agricultural Production: Implications for the Development of Conservation Agriculture in Kenya and Uganda

ERIC Educational Resources Information Center

Moore, Keith M.; Lamb, Jennifer N.; Sikuku, Dominic Ngosia; Ashilenje, Dennis S.; Laker-Ojok, Rita; Norton, Jay

2014-01-01

Purpose: This article investigates the extent of multiple knowledges among smallholders and connected non-farm agents around Mount Elgon in Kenya and Uganda in order to build the communicative competence needed to scale up conservation agriculture production systems (CAPS). Design/methodology/approach: Our methodological approach examines local…

Changing a Generation's Way of Thinking: Teaching Computational Thinking through Programming

ERIC Educational Resources Information Center

Buitrago Flórez, Francisco; Casallas, Rubby; Hernández, Marcela; Reyes, Alejandro; Restrepo, Silvia; Danies, Giovanna

2017-01-01

Computational thinking (CT) uses concepts that are essential to computing and information science to solve problems, design and evaluate complex systems, and understand human reasoning and behavior. This way of thinking has important implications in computer sciences as well as in almost every other field. Therefore, we contend that CT should be…

On-Line Learning and the Implications for School Design

ERIC Educational Resources Information Center

Stack, Greg

2011-01-01

"Disrupting Class," published in 2008, is the story of how disruptive innovation, innovation that changes the business model organizations, will fundamentally change the American school system. The book's most startling prediction is that half of all high school classes will be on-line by 2019. In considering these predictions, the author began to…

Active controls technology to maximize structural efficiency

NASA Technical Reports Server (NTRS)

Hoy, J. M.; Arnold, J. M.

1978-01-01

The implication of the dependence on active controls technology during the design phase of transport structures is considered. Critical loading conditions are discussed along with probable ways of alleviating these loads. Why fatigue requirements may be critical and can only be partially alleviated is explained. The significance of certain flutter suppression system criteria is examined.

The Barriers to Achieving the Wider Goals of General Education and Their Implications for the British Educational Research Association.

ERIC Educational Resources Information Center

Raven, John

1990-01-01

Advocates revamping the British educational system from technical-rational content model to student-centered process programs designed to promote critical thinking, individual initiative, and communication skills. Discusses obstacles to this educational reform, emphasizing research orientation. Urges the British Educational Research Association to…

IELTS: Global Implications of Curriculum and Materials Design.

ERIC Educational Resources Information Center

Wallace, Craig

1997-01-01

Questions the removal of a link between reading and writing tasks in the International English Language Testing System (IELTS) examinations on two grounds: that this removal is prejudicial to those students whose native cultures may not provide the appropriate schemata to effectively write; and that it is unrealistic in terms of the measurement of…

The Geography of Access and Excellence: Spatial Diversity in Higher Education System Design

ERIC Educational Resources Information Center

Metcalfe, Amy Scott

2009-01-01

In a "settler society" such as Canada, inequalities in higher education have geo-political dimensions, necessitating a theoretical framework that considers the geographic distribution of material wealth and power. This paper explores both the economic and social implications of the geographical distribution of the higher education system…

Family-Centered Early Intervention for Communication Disorders: Prevention and Treatment. Excellence in Practice Series.

ERIC Educational Resources Information Center

Donahue-Kilburg, Gail

This book is designed to provide a broad range of information on family structure and function in an increasingly multicultural society, family system characteristics and the implications for intervention, communication development in the family context, the nature and delivery of family centered-services, specific requirements of Public Law…

Nitrogen composition in urban runoff--implications for stormwater management.

PubMed

Taylor, Geoff D; Fletcher, Tim D; Wong, Tony H F; Breen, Peter F; Duncan, Hugh P

2005-05-01

A study was conducted to characterise the composition of nitrogen in urban stormwater in Melbourne, Australia, during baseflows and storm events, and to compare the results with international data. Nitrogen in Melbourne stormwater was predominantly dissolved (approximately 80%), with ammonia the least-abundant form (approximately 11%). Concentrations of nitrogen species did not vary significantly between baseflow and storms, although the proportion of nitrogen in particulate form was higher during storm events (p = 0.04). Whilst the composition of nitrogen in Melbourne was broadly consistent with international data, the level of dissolved inorganic nitrogen was higher in Melbourne (mu = 48% during baseflows and 49% during storms) than in the international literature (mu = 29%). Limitations in the international dataset precluded comparison of total dissolved nitrogen. The results have implications for stormwater management. Whilst nitrogen species concentrations are variable, they are not strongly related to flow conditions, so treatment systems must be designed to cope with stochastic inflow concentrations at all times. To optimise their performance, stormwater treatments should be designed to improve dissolved nitrogen removal. Further research is needed to improve the ability of treatment systems to achieve this aim.

Adaptive and Adaptable Automation Design: A Critical Review of the Literature and Recommendations for Future Research

NASA Technical Reports Server (NTRS)

Prinzel, Lawrence J., III; Kaber, David B.

2006-01-01

This report presents a review of literature on approaches to adaptive and adaptable task/function allocation and adaptive interface technologies for effective human management of complex systems that are likely to be issues for the Next Generation Air Transportation System, and a focus of research under the Aviation Safety Program, Integrated Intelligent Flight Deck Project. Contemporary literature retrieved from an online database search is summarized and integrated. The major topics include the effects of delegation-type, adaptable automation on human performance, workload and situation awareness, the effectiveness of various automation invocation philosophies and strategies to function allocation in adaptive systems, and the role of user modeling in adaptive interface design and the performance implications of adaptive interface technology.

Advanced Pedestrian Positioning System to Smartphones and Smartwatches

PubMed Central

Correa, Alejandro; Munoz Diaz, Estefania; Bousdar Ahmed, Dina; Morell, Antoni; Lopez Vicario, Jose

2016-01-01

In recent years, there has been an increasing interest in the development of pedestrian navigation systems for satellite-denied scenarios. The popularization of smartphones and smartwatches is an interesting opportunity for reducing the infrastructure cost of the positioning systems. Nowadays, smartphones include inertial sensors that can be used in pedestrian dead-reckoning (PDR) algorithms for the estimation of the user’s position. Both smartphones and smartwatches include WiFi capabilities allowing the computation of the received signal strength (RSS). We develop a new method for the combination of RSS measurements from two different receivers using a Gaussian mixture model. We also analyze the implication of using a WiFi network designed for communication purposes in an indoor positioning system when the designer cannot control the network configuration. In this work, we design a hybrid positioning system that combines inertial measurements, from low-cost inertial sensors embedded in a smartphone, with RSS measurements through an extended Kalman filter. The system has been validated in a real scenario, and results show that our system improves the positioning accuracy of the PDR system thanks to the use of two WiFi receivers. The designed system obtains an accuracy up to 1.4 m in a scenario of 6000 m2. PMID:27845715

Using interactive visual reasoning to support sense-making: implications for design.

PubMed

Kodagoda, Neesha; Attfield, Simon; Wong, B L William; Rooney, Chris; Choudhury, Sharmin Tinni

2013-12-01

This research aims to develop design guidelines for systems that support investigators and analysts in the exploration and assembly of evidence and inferences. We focus here on the problem of identifying candidate 'influencers' within a community of practice. To better understand this problem and its related cognitive and interaction needs, we conducted a user study using a system called INVISQUE (INteractive Visual Search and QUery Environment) loaded with content from the ACM Digital Library. INVISQUE supports search and manipulation of results over a freeform infinite 'canvas'. The study focuses on the representations user create and their reasoning process. It also draws on some pre-established theories and frameworks related to sense-making and cognitive work in general, which we apply as a 'theoretical lenses' to consider findings and articulate solutions. Analysing the user-study data in the light of these provides some understanding of how the high-level problem of identifying key players within a domain can translate into lower-level questions and interactions. This, in turn, has informed our understanding of representation and functionality needs at a level of description which abstracts away from the specifics of the problem at hand to the class of problems of interest. We consider the study outcomes from the perspective of implications for design.

Using systems thinking to support clinical system transformation.

PubMed

Best, Allan; Berland, Alex; Herbert, Carol; Bitz, Jennifer; van Dijk, Marlies W; Krause, Christina; Cochrane, Douglas; Noel, Kevin; Marsden, Julian; McKeown, Shari; Millar, John

2016-05-16

Purpose - The British Columbia Ministry of Health's Clinical Care Management initiative was used as a case study to better understand large-scale change (LSC) within BC's health system. Using a complex system framework, the purpose of this paper is to examine mechanisms that enable and constrain the implementation of clinical guidelines across various clinical settings. Design/methodology/approach - Researchers applied a general model of complex adaptive systems plus two specific conceptual frameworks (realist evaluation and system dynamics mapping) to define and study enablers and constraints. Focus group sessions and interviews with clinicians, executives, managers and board members were validated through an online survey. Findings - The functional themes for managing large-scale clinical change included: creating a context to prepare clinicians for health system transformation initiatives; promoting shared clinical leadership; strengthening knowledge management, strategic communications and opportunities for networking; and clearing pathways through the complexity of a multilevel, dynamic system. Research limitations/implications - The action research methodology was designed to guide continuing improvement of implementation. A sample of initiatives was selected; it was not intended to compare and contrast facilitators and barriers across all initiatives and regions. Similarly, evaluating the results or process of guideline implementation was outside the scope; the methods were designed to enable conversations at multiple levels - policy, management and practice - about how to improve implementation. The study is best seen as a case study of LSC, offering a possible model for replication by others and a tool to shape further dialogue. Practical implications - Recommended action-oriented strategies included engaging local champions; supporting local adaptation for implementation of clinical guidelines; strengthening local teams to guide implementation; reducing change fatigue; ensuring adequate resources; providing consistent communication especially for front-line care providers; and supporting local teams to demonstrate the clinical value of the guidelines to their colleagues. Originality/value - Bringing a complex systems perspective to clinical guideline implementation resulted in a clear understanding of the challenges involved in LSC.

Future earth orbit transportation systems/technology implications

NASA Technical Reports Server (NTRS)

Henry, B. Z.; Decker, J. P.

1976-01-01

Assuming Space Shuttle technology to be state-of-the-art, projected technological advances to improve the capabilities of single-stage-to-orbit (SSTO) derivatives are examined. An increase of about 30% in payload performance can be expected from upgrading the present Shuttle system through weight and drag reductions and improvements in the propellants and engines. The ODINEX (Optimal Design Integration Executive Computer Program) program has been used to explore design options. An advanced technology SSTO baseline system derived from ODINEX analysis has a conventional wing-body configuration using LOX/LH engines, three with two-position nozzles with expansion ratios of 40 and 200 and four with fixed nozzles with an expansion ratio of 40. Two assisted-takeoff approaches are under consideration in addition to a concept in which the orbital vehicle takes off empty using airbreathing propulsion and carries out a rendezvous with two large cryogenic tankers carrying propellant at an altitude of 6100 m. Further approaches under examination for propulsion, aerothermodynamic design, and design integration are described.

Fusing Quantitative Requirements Analysis with Model-based Systems Engineering

NASA Technical Reports Server (NTRS)

Cornford, Steven L.; Feather, Martin S.; Heron, Vance A.; Jenkins, J. Steven

2006-01-01

A vision is presented for fusing quantitative requirements analysis with model-based systems engineering. This vision draws upon and combines emergent themes in the engineering milieu. "Requirements engineering" provides means to explicitly represent requirements (both functional and non-functional) as constraints and preferences on acceptable solutions, and emphasizes early-lifecycle review, analysis and verification of design and development plans. "Design by shopping" emphasizes revealing the space of options available from which to choose (without presuming that all selection criteria have previously been elicited), and provides means to make understandable the range of choices and their ramifications. "Model-based engineering" emphasizes the goal of utilizing a formal representation of all aspects of system design, from development through operations, and provides powerful tool suites that support the practical application of these principles. A first step prototype towards this vision is described, embodying the key capabilities. Illustrations, implications, further challenges and opportunities are outlined.

Safety implications from design exceptions.

DOT National Transportation Integrated Search

2002-03-01

The objectives of this study were to: a) summarize past design exceptions to document their frequency and reason for their use and b) determine if any adverse safety implications can be related to adopting design policies and practices related to des...

The Problem of Size in Robust Design

NASA Technical Reports Server (NTRS)

Koch, Patrick N.; Allen, Janet K.; Mistree, Farrokh; Mavris, Dimitri

1997-01-01

To facilitate the effective solution of multidisciplinary, multiobjective complex design problems, a departure from the traditional parametric design analysis and single objective optimization approaches is necessary in the preliminary stages of design. A necessary tradeoff becomes one of efficiency vs. accuracy as approximate models are sought to allow fast analysis and effective exploration of a preliminary design space. In this paper we apply a general robust design approach for efficient and comprehensive preliminary design to a large complex system: a high speed civil transport (HSCT) aircraft. Specifically, we investigate the HSCT wing configuration design, incorporating life cycle economic uncertainties to identify economically robust solutions. The approach is built on the foundation of statistical experimentation and modeling techniques and robust design principles, and is specialized through incorporation of the compromise Decision Support Problem for multiobjective design. For large problems however, as in the HSCT example, this robust design approach developed for efficient and comprehensive design breaks down with the problem of size - combinatorial explosion in experimentation and model building with number of variables -and both efficiency and accuracy are sacrificed. Our focus in this paper is on identifying and discussing the implications and open issues associated with the problem of size for the preliminary design of large complex systems.

On Ambiguities in SAR Design

NASA Technical Reports Server (NTRS)

Freeman, Anthony

2006-01-01

Ambiguities are an aliasing effect caused by the periodic sampling of the scene backscatter inherent to pulsed radar systems such as Synthetic Aperture radar (SAR). In this paper we take a fresh look at the relationship between SAR range and azimuth ambiguity constraints on the allowable pulse repetition frequency (PRF) and the antenna length. We show that for high squint angles smaller antennas may be feasible in some cases. For some applications, the ability to form a synthetic aperture at high squint angles is desirable, but the size of the antenna causes problems in the design of systems capable of such operation. This is because the SAR system design is optimized for a side-looking geometry. In two examples design examples we take a suboptimum antenna size and examine the performance in terms of azimuth resolution and swath width as a function of squint angle. We show that for stripmap SARs, the swath width is usually worse for off-boresight squint angles, because it is severely limited by range walk, except in cases where we relax the spatial resolution. We consider the implications for the design of modest-resolution, narrow swath, scanning SAR scatterometers .

Life cycle assessment of domestic and agricultural rainwater harvesting systems.

PubMed

Ghimire, Santosh R; Johnston, John M; Ingwersen, Wesley W; Hawkins, Troy R

2014-04-01

To further understanding of the environmental implications of rainwater harvesting and its water savings potential relative to conventional U.S. water delivery infrastructure, we present a method to perform life cycle assessment of domestic rainwater harvesting (DRWH) and agricultural rainwater harvesting (ARWH) systems. We also summarize the design aspects of DRWH and ARWH systems adapted to the Back Creek watershed, Virginia. The baseline design reveals that the pump and pumping electricity are the main components of DRWH and ARWH impacts. For nonpotable uses, the minimal design of DRWH (with shortened distribution distance and no pump) outperforms municipal drinking water in all environmental impact categories except ecotoxicity. The minimal design of ARWH outperforms well water in all impact categories. In terms of watershed sustainability, the two minimal designs reduced environmental impacts, from 58% to 78% energy use and 67% to 88% human health criteria pollutants, as well as avoiding up to 20% blue water (surface/groundwater) losses, compared to municipal drinking water and well water. We address potential environmental and human health impacts of urban and rural RWH systems in the region. The Building for Environmental and Economic Sustainability (BEES) model-based life cycle inventory data were used for this study.

Historical account of the national health insurance formulation in Kenya: experiences from the past decade.

PubMed

Abuya, Timothy; Maina, Thomas; Chuma, Jane

2015-02-12

Many Low-and-Middle-Income countries are considering reviewing their health financing systems to meet the principles of Universal Health Coverage (UHC). One financing mechanism, which has dominated UHC reforms, is the development of health insurance schemes. We trace the historical development of the National Health Insurance (NHI) policy, illuminate stakeholders' perceptions on the design to inform future development of health financing policies in Kenya. We conducted a retrospective policy analysis of the development of a NHI policy in Kenya using data from document reviews and seven in depth interviews with key stakeholders involved in the NHI design. Analysis was conducted using a thematic framework. The design of a NHI scheme was marked by complex interaction of the actor's understanding of the design, proposed implementation strategies and the covert opposition of the reform due to several reasons. First, actor's perception of the cost of the NHI design and its implication to the economy generated opposition. This was due to inadequate communication strategies to articulate the policy, leading to a vacuum of factual information flow to various players. Secondly, perceived fear of implications of the changes among private sector players threatened support and success gained. Thirdly, underlying mistrust associated with perceived lack of government's commitment towards transparency and good governance affected active engagement of all key players dampening the spirit of collective bargain breeding opposition. Finally, some international actors perceived a clash of their role and that of international programs based on vertical approaches that were inherent in the health system. The thrust towards UHC using NHI schemes should not only focus on the design of a viable NHI package but should also involve stakeholder engagements, devise ways of improving the health care system, enhance transparency and develop adequate governance structures to institutions mandated to provide leadership in the reform process to overcome covert opposition.

Understanding social forces involved in diabetes outcomes: a systems science approach to quality-of-life research.

PubMed

Lounsbury, David W; Hirsch, Gary B; Vega, Chawntel; Schwartz, Carolyn E

2014-04-01

The field of quality-of-life (QOL) research would benefit from learning about and integrating systems science approaches that model how social forces interact dynamically with health and affect the course of chronic illnesses. Our purpose is to describe the systems science mindset and to illustrate the utility of a system dynamics approach to promoting QOL research in chronic disease, using diabetes as an example. We build a series of causal loop diagrams incrementally, introducing new variables and their dynamic relationships at each stage. These causal loop diagrams demonstrate how a common set of relationships among these variables can generate different disease and QOL trajectories for people with diabetes and also lead to a consideration of non-clinical (psychosocial and behavioral) factors that can have implications for program design and policy formulation. The policy implications of the causal loop diagrams are discussed, and empirical next steps to validate the diagrams and quantify the relationships are described.

An integrated science-based methodology to assess potential risks and implications of engineered nanomaterials.

PubMed

Tolaymat, Thabet; El Badawy, Amro; Sequeira, Reynold; Genaidy, Ash

2015-11-15

There is an urgent need for broad and integrated studies that address the risks of engineered nanomaterials (ENMs) along the different endpoints of the society, environment, and economy (SEE) complex adaptive system. This article presents an integrated science-based methodology to assess the potential risks of engineered nanomaterials. To achieve the study objective, two major tasks are accomplished, knowledge synthesis and algorithmic computational methodology. The knowledge synthesis task is designed to capture "what is known" and to outline the gaps in knowledge from ENMs risk perspective. The algorithmic computational methodology is geared toward the provision of decisions and an understanding of the risks of ENMs along different endpoints for the constituents of the SEE complex adaptive system. The approach presented herein allows for addressing the formidable task of assessing the implications and risks of exposure to ENMs, with the long term goal to build a decision-support system to guide key stakeholders in the SEE system towards building sustainable ENMs and nano-enabled products. Published by Elsevier B.V.

Green buildings need good ergonomics.

PubMed

Hedge, A; Dorsey, J A

2013-01-01

A retrospective post-occupancy evaluation survey of 44 occupants in two Leadership in Energy and Environmental Design (LEED) Platinum buildings on a US college campus is reported. The Internet survey covered a range of indoor environment and ergonomics issues. Results show that working in these buildings were a generally positive experience for their health, performance and satisfaction. However, in one building there were persistent issues of variability in air temperature, air freshness, air quality and noise that affected the perceived health and performance of the occupants. Although the buildings were energy-efficient and sustainable structures, ergonomics design issues were identified. Implications for the role of ergonomics in green buildings and in the US LEED rating system are discussed. This survey identified a number of ergonomics design issues present in the LEED Platinum energy-efficient and sustainable buildings that were studied. These results highlight the importance of integrating ergonomics design into green buildings as a component in the US LEED rating system.

The Historical and Situated Nature Design Experiments--Implications for Data Analysis

ERIC Educational Resources Information Center

Krange, I.; Ludvigsen, Sten

2009-01-01

This article is a methodological contribution to the use of design experiments in educational research. We will discuss the implications of a historical and situated interpretation to design experiments, the consequences this has for the analysis of the collected data and empirically based suggestions to improve the designs of the computer-based…

A sustainable system of systems approach: a new HFE paradigm.

PubMed

Thatcher, Andrew; Yeow, Paul H P

2016-01-01

Sustainability issues such as natural resource depletion, pollution and poor working conditions have no geographical boundaries in our interconnected world. To address these issues requires a paradigm shift within human factors and ergonomics (HFE), to think beyond a bounded, linear model understanding towards a broader systems framework. For this reason, we introduce a sustainable system of systems model that integrates the current hierarchical conceptualisation of possible interventions (i.e., micro-, meso- and macro-ergonomics) with important concepts from the sustainability literature, including the triple bottom line approach and the notion of time frames. Two practical examples from the HFE literature are presented to illustrate the model. The implications of this paradigm shift for HFE researchers and practitioners are discussed and include the long-term sustainability of the HFE community and comprehensive solutions to problems that consider the emergent issues that arise from this interconnected world. A sustainable world requires a broader systems thinking than that which currently exists in ergonomics. This study proposes a sustainable system of systems model that incorporates ideas from the ecological sciences, notably a nested hierarchy of systems and a hierarchical time dimension. The implications for sustainable design and the sustainability of the HFE community are considered.

A Review of Safety and Design Requirements of the Artificial Pancreas.

PubMed

Blauw, Helga; Keith-Hynes, Patrick; Koops, Robin; DeVries, J Hans

2016-11-01

As clinical studies with artificial pancreas systems for automated blood glucose control in patients with type 1 diabetes move to unsupervised real-life settings, product development will be a focus of companies over the coming years. Directions or requirements regarding safety in the design of an artificial pancreas are, however, lacking. This review aims to provide an overview and discussion of safety and design requirements of the artificial pancreas. We performed a structured literature search based on three search components-type 1 diabetes, artificial pancreas, and safety or design-and extended the discussion with our own experiences in developing artificial pancreas systems. The main hazards of the artificial pancreas are over- and under-dosing of insulin and, in case of a bi-hormonal system, of glucagon or other hormones. For each component of an artificial pancreas and for the complete system we identified safety issues related to these hazards and proposed control measures. Prerequisites that enable the control algorithms to provide safe closed-loop control are accurate and reliable input of glucose values, assured hormone delivery and an efficient user interface. In addition, the system configuration has important implications for safety, as close cooperation and data exchange between the different components is essential.

A biocatalytic cascade with several output signals—towards biosensors with different levels of confidence

PubMed Central

Guz, Nataliia; Halámek, Jan; Rusling, James F.; Katz, Evgeny

2014-01-01

The biocatalytic cascade based on enzyme-catalyzed reactions activated by several biomolecular input signals and producing output signal after each reaction step was developed as an example of a logically reversible information processing system. The model system was designed to mimic the operation of concatenated AND logic gates with optically readable output signals generated at each step of the logic operation. Implications include concurrent bioanalyses and data interpretation for medical diagnostics. PMID:24748446

Innate immunity in HIV infection and implications for vaccine design: a summary of the workshop held at the National Institute of Allergy and Infectious Diseases, Bethesda on February 25-26, 2010.

PubMed

Bansal, Geetha P; Leitner, Wolfgang W

2010-12-06

The search for an effective HIV vaccine continues to be a challenge. Several candidates have been tested in preclinical protocols, and a few have been tested in clinical trials without resounding success. It is unclear why vaccine approaches to control HIV infection have been unsuccessful, but opportunities to dissect the causes for the failure have surfaced from recent work on the virology, immunology and pathogenesis of HIV and from analysis of vaccine studies. The significance of the innate immune system in HIV infection may provide new paths to discover effective approaches. This report summarizes a workshop held to discuss the role of selected aspects of innate immunity to viral infections and successful vaccines that may have important implications for designing effective HIV vaccines. Copyright © 2010. Published by Elsevier Ltd.. All rights reserved.

Test of an orbiting hydrogen maser clock system using laser time transfer

NASA Technical Reports Server (NTRS)

Vessot, Robert F. C.; Mattison, Edward M.; Nystrom, G. U.; Decher, Rudolph

1992-01-01

We describe a joint Smithsonian Astrophysical Laboratory/National Aeronautics and Space Administration (SAO/NASA) program for flight testing a atomic hydrogen maser clock system designed for long-term operation in space. The clock system will be carried by a shuttle-launched EURECA spacecraft. Comparisons with earth clocks to measure the clock's long-term frequency stability (tau = 10(exp 4) seconds) will be made using laser time transfer from existing NASA laser tracking stations. We describe the design of the maser clock and its control systems, and the laser timing technique. We describe the precision of station time synchronization and the limitations in the comparison between the earth and space time scales owing to gravitational and relativistic effects. We will explore the implications of determining the spacecraft's location by an on-board Global Position System (GPS) receiver, and of using microwave techniques for time and frequency transfer.

National Efforts to Bring Reform to Scale in High-Poverty Schools: Outcomes and Implications

ERIC Educational Resources Information Center

Borman, Geoffrey D.

2005-01-01

Education in the United States is a decentralized system composed of highly variable practices, programs, and school contexts. The primary technology of education, teaching, is highly complex and is typically designed and implemented by teachers who have traditionally enjoyed a great deal of autonomy and independence from regular inspection. The…

Carbon pools and fluxes in small temperate forest landscapes: Variability and implications for sampling design

Treesearch

John B. Bradford; Peter Weishampel; Marie-Louise Smith; Randall Kolka; Richard A. Birdsey; Scott V. Ollinger; Michael G. Ryan

2010-01-01

Assessing forest carbon storage and cycling over large areas is a growing challenge that is complicated by the inherent heterogeneity of forest systems. Field measurements must be conducted and analyzed appropriately to generate precise estimates at scales large enough for mapping or comparison with remote sensing data. In this study we examined...

CMU/IBM Usability Study: Final Report. CDC Technical Report No. 11.

ERIC Educational Resources Information Center

Ballay, Joseph M.; And Others

This report focuses on the activities and findings of the fourth phase of research carried out at Carnegie-Mellon University (CMU) on the development of user documentation for computer-aided design (CAD) systems. The first of four major sections provides an overview of recent research, issues involved in the research, and implications of the…

Navigating the Information Ocean: Charting the Course. Abstracts from the Academic Library Association of Ohio Annual Conference (Columbus, Ohio, November 4, 1994).

ERIC Educational Resources Information Center

Academic Library Association of Ohio.

Abstracts of 14 papers presented at the conference are provided here. Titles are: "Electronic Information Terraforming: Designing and Implementing a Front-end System Using World-Wide Web Technology" (Abbie Basile; And Others); "Characteristics of Generation X and Implications for Reference and Instructional Services" (Catherine…

A Marketing Assessment of Beneficiaries at Kimbrough Army Community Hospital

DTIC Science & Technology

1993-05-01

environment, organizational goal formulation, strategy formulation, Marketing Assessment 10 organization and systems design ( Kotler , 1987). Second...environmental analysis itself is concerned with identifying marketing opportunities, threats, environmental trends and their implications ( Kotler , 1987...decision to develop beneficiary subgroups was based on the marketing principle of market segmentation which assumes that no one strategy will work for

Predicting General Academic Performance and Identifying the Differential Contribution of Participating Variables Using Artificial Neural Networks

ERIC Educational Resources Information Center

Musso, Mariel F.; Kyndt, Eva; Cascallar, Eduardo C.; Dochy, Filip

2013-01-01

Many studies have explored the contribution of different factors from diverse theoretical perspectives to the explanation of academic performance. These factors have been identified as having important implications not only for the study of learning processes, but also as tools for improving curriculum designs, tutorial systems, and students'…

Alternative silvicultural practices in Appalachian forest ecosystems: implications for species diversity, ecosystem resilience, and commercial timber production

Treesearch

Thomas R. Fox; Carola A. Haas; David W. Smith; David L. Loftis; Shepard M. Zedaker; Robert H. Jones; A.L. Hammett

2007-01-01

Increasing demands for timber and non-timber forest products often conflict with demands to maintain biodiversity and ecosystem processes. To examine tradeoffs between these goals, we implemented six alternative management systems using a stand-level, replicated experiment. The treatments included four silvicultural regeneration methods designed to sustain timber...

Implications of multiplane-multispeed balancing for future turbine engine design and cost

NASA Technical Reports Server (NTRS)

Badgley, R. H.

1974-01-01

This paper describes several alternative approaches, provided by multiplane-multispeed balancing, to traditional gas turbine engine manufacture and assembly procedures. These alternatives, which range from addition of trim-balancing at the end of the traditional assembly process to modular design of the rotating system for assembly and balancing external to the engine, require attention by the engine designer as an integral part of the design process. Since multiplane-multispeed balancing may be incorporated at one or more of several points during manufacture-assembly, its deliberate use is expected to provide significant cost and performance (reduced vibration) benefits. Moreover, its availability provides the designer with a firm base from which he may advance, with reasonable assurance of success, into the flexible rotor dynamic regime.

Security Implications of Physical Design Attributes in the Emergency Department.

PubMed

Pati, Debajyoti; Pati, Sipra; Harvey, Thomas E

2016-07-01

Security, a subset of safety, is equally important in the efficient delivery of patient care. The emergency department (ED) is susceptible to violence creating concerns for the safety and security of patients, staff, and visitors and for the safe and efficient delivery of care. Although there is an implicit and growing recognition of the role of the physical environment, interventions typically have been at the microlevel. The objective of this study was to identify physical design attributes that potentially influence safety and efficiency of ED operations. An exploratory, qualitative research design was adopted to examine the efficiency and safety correlates of ED physical design attributes. The study comprised a multimeasure approach involving multidisciplinary gaming, semistructured interviews, and touring interviews of frontline staff in four EDs at three hospital systems across three states. Five macro physical design attributes (issues that need to be addressed at the design stage and expensive to rectify once built) emerged from the data as factors substantially associated with security issues. They are design issues pertaining to (a) the entry zone, (b) traffic management, (c) patient room clustering, (d) centralization versus decentralization, and (e) provisions for special populations. Data from this study suggest that ED security concerns are generally associated with three sources: (a) gang-related violence, (b) dissatisfied patients, and (c) behavioral health patients. Study data show that physical design has an important role in addressing the above-mentioned concerns. Implications for ED design are outlined in the article. © The Author(s) 2016.

A Synthesis of Relevant Literature on the Development of Emotional Competence: Implications for Design of Augmentative and Alternative Communication Systems.

PubMed

Na, Ji Young; Wilkinson, Krista; Karny, Meredith; Blackstone, Sarah; Stifter, Cynthia

2016-08-01

Emotional competence refers to the ability to identify, respond to, and manage one's own and others' emotions. Emotional competence is critical to many functional outcomes, including making and maintaining friends, academic success, and community integration. There appears to be a link between the development of language and the development of emotional competence in children who use speech. Little information is available about these issues in children who rely on augmentative and alternative communication (AAC). In this article, we consider how AAC systems can be designed to support communication about emotions and the development of emotional competence. Because limited research exists on communication about emotions in a context of aided AAC, theory and research from other fields (e.g., psychology, linguistics, child development) is reviewed to identify key features of emotional competence and their possible implications for AAC design and intervention. The reviewed literature indicated that the research and clinical attention to emotional competence in children with disabilities is encouraging. However, the ideas have not been considered specifically in the context of aided AAC. On the basis of the reviewed literature, we offer practical suggestions for system design and AAC use for communication about emotions with children who have significant disabilities. Three key elements of discussing emotions (i.e., emotion name, reason, and solution) are suggested for inclusion in order to provide these children with opportunities for a full range of discussion about emotions. We argue that supporting communication about emotions is as important for children who use AAC as it is for children who are learning speech. This article offers a means to integrate information from other fields for the purpose of enriching AAC supports.

The Building Bridges Project: Involving Older Adults in the Design of a Communication Technology to Support Peer-to-Peer Social Engagement

NASA Astrophysics Data System (ADS)

Wherton, Joseph; Prendergast, David

There are a variety of factors that can lead to social isolation and loneliness in old age, including decline in physical and mental health, as well as change to social environment. The Building Bridges project explores how communication technology can help older adults remain socially connected. This paper will first provide an overview of a prototype communication system designed to support peer-to-peer group interaction. A description of the user-centered design process will be provided to demonstrate the importance of involving older adults at the earliest stages. The implications for designing new technology for older adults are discussed.

Cross-hierarchy systems principles.

PubMed

Goentoro, Lea

2017-02-01

One driving motivation of systems biology is the search for general principles that govern the design of biological systems. But questions often arise as to what kind of general principles biology could have. Concepts from engineering such as robustness and modularity are indeed becoming a regular way of describing biological systems. Another source of potential general principles is the emerging similarities found in processes across biological hierarchies. In this piece, I describe several emerging cross-hierarchy similarities. Identification of more cross-hierarchy principles, and understanding the implications these convergence have on the construction of biological systems, I believe, present exciting challenges for systems biology in the decades to come.

Solar energy in buildings: Implications for California energy policy

NASA Technical Reports Server (NTRS)

Hirshberg, A. S.; Davis, E. S.

1977-01-01

An assessment of the potential of active solar energy systems for buildings in California is summarized. The technology used for solar heating, cooling, and water heating in buildings is discussed. The major California weather zones and the solar energy designs are described, as well as the sizing of solar energy systems and their performance. The cost of solar energy systems is given both at current prices and at prices consistent with optimistic estimates for the cost of collectors. The main institutional barriers to the wide spread use of solar energy are summarized.

Personalizing Knowledge Delivery Services for Emerging Knowledge Processes (EKPs): A Conceptual Framework

NASA Technical Reports Server (NTRS)

Majchrzak, Ann; Chellappa, Ramnath K.; Cooper, Lynne P.; Hars, Alexander

2003-01-01

The contents include: 1) What do most KMS in use today assume?; 2) Assumptions are violated when KMS is used by EKP workers - Why?; 3) Current State of KMS for EKPs are inadequate; 4) What would an "adequate" KMS for EKPs look like?; 5) "User-as-Consumer" Analogue: Ecommerce/Eem ployee Services; 6) Why is an ideal KMS for EKPs hard to achieve?; 7) So, what type of KMS design would work?; 8) Human-Based KMS for EKP - Proposal Call Managers at R&DLAB; 9) Proposal Call Managers (PCMs); 10) Specific PCM tasks; 11) Why is a R&DLAB PCM a human metaphor for a KMS for EKP?; 12) Data Collection; 13) Finding #1; 14) Finding #2; 15) Finding #3; 16) Factors affecting How/when; 17) Finding #4; 18) Finding #5; 19) Implication#l for a KMS for EKP: From System to Service; 20) Implication #2: From technology or human-centric to Mixed Mode; 21) Implication #3: From Simple User Profiles to Dynamic Delivery Profiles; 22) Implication #4: Maintaining a trustworthy environment; 23) Implication #5: Constructing a dynamic delivery profile; 24) Implications for Research: Model; and 25) Example Research Qs on KMS Support for EKPs.

X-38 NASA/DLR/ESA-Dassault Aviation Integrated Aerodynamic and Aerothermodynamic Activities

NASA Technical Reports Server (NTRS)

Labbe, Steve G.; Perez, Leo F.; Fitzgerald, Steve; Longo, Jose; Rapuc, Marc; Molina, Rafael; Nicholson, Leonard S. (Technical Monitor)

1999-01-01

The characterization of the aeroshape selected for the X-38 [Crew Return Vehicle (CRV) demonstrator] is presently being performed as a cooperative endeavour between NASA, DLR (through its TETRA Program), and European Space Agency (ESA) with Dassault Aviation integrating the aerodynamic and aerothermodynamic activities. The methodologies selected for characterizing the aerodynamic and aerothermodynamic environment of the X-38 are presented. Also, the implications for related disciplines such as Guidance Navigation and Control (GN&C) with its corresponding Flight Control System (FCS), Structural, and Thermal Protection System (TPS) design are discussed. An attempt is made at defining the additional activities required to support the design of a derived operational CRV.

Verification Failures: What to Do When Things Go Wrong

NASA Astrophysics Data System (ADS)

Bertacco, Valeria

Every integrated circuit is released with latent bugs. The damage and risk implied by an escaped bug ranges from almost imperceptible to potential tragedy; unfortunately it is impossible to discern within this range before a bug has been exposed and analyzed. While the past few decades have witnessed significant efforts to improve verification methodology for hardware systems, these efforts have been far outstripped by the massive complexity of modern digital designs, leading to product releases for which an always smaller fraction of system's states has been verified. The news of escaped bugs in large market designs and/or safety critical domains is alarming because of safety and cost implications (due to replacements, lawsuits, etc.).

Shuttle/ISS EMU Failure History and the Impact on Advanced EMU PLSS Design

NASA Technical Reports Server (NTRS)

Campbell, Colin

2011-01-01

As the Shuttle/ISS EMU Program exceeds 30 years in duration and is still successfully supporting the needs of the International Space Station (ISS), a critical benefit of such a long running program with thorough documentation of system and component failures is the ability to study and learn from those failures when considering the design of the next generation space suit. Study of the subject failure history leads to changes in the Advanced EMU Portable Life Support System (PLSS) schematic, selected component technologies, as well as the planned manner of ground testing. This paper reviews the Shuttle/ISS EMU failure history and discusses the implications to the AEMU PLSS.

Shuttle/ISS EMU Failure History and the Impact on Advanced EMU PLSS Design

NASA Technical Reports Server (NTRS)

Campbell, Colin

2015-01-01

As the Shuttle/ISS EMU Program exceeds 30 years in duration and is still supporting the needs of the International Space Station (ISS), a critical benefit of such a long running program with thorough documentation of system and component failures is the ability to study and learn from those failures when considering the design of the next generation space suit. Study of the subject failure history leads to changes in the Advanced EMU Portable Life Support System (PLSS) schematic, selected component technologies, as well as the planned manner of ground testing. This paper reviews the Shuttle/ISS EMU failure history and discusses the implications to the AEMU PLSS.

The effects of time delay in man-machine control systems: Implications for design of flight simulator Visual-Display-Delay compensation

NASA Technical Reports Server (NTRS)

Crane, D. F.

1984-01-01

When human operators are performing precision tracking tasks, their dynamic response can often be modeled by quasilinear describing functions. That fact permits analysis of the effects of delay in certain man machine control systems using linear control system analysis techniques. The analysis indicates that a reduction in system stability is the immediate effect of additional control system delay, and that system characteristics moderate or exaggerate the importance of the delay. A selection of data (simulator and flight test) consistent with the analysis is reviewed. Flight simulator visual-display delay compensation, designed to restore pilot aircraft system stability, was evaluated in several studies which are reviewed here. The studies range from single-axis, tracking-task experiments (with sufficient subjects and trials to establish the statistical significance of the results) to a brief evaluation of compensation of a computer generated imagery (CGI) visual display system in a full six degree of freedom simulation. The compensation was effective, improvements in pilot performance and workload or aircraft handling qualities rating (HQR) were observed. Results from recent aircraft handling qualities research literature, which support the compensation design approach, are also reviewed.

Status of ITER Cryodistribution and Cryoline project

NASA Astrophysics Data System (ADS)

Sarkar, B.; Vaghela, H.; Shah, N.; Bhattacharya, R.; Choukekar, K.; Patel, P.; Kapoor, H.; Srinivasa, M.; Chang, H. S.; Badgujar, S.; Monneret, E.

2017-02-01

The system of ITER Cryodistribution (CD) and Cryolines (CLs) is an integral interface between the Cryoplant systems and the superconducting (SC) magnets as well as Cryopumps (CPs). The project has progressed from the conceptual stage to the industrial stage. The subsystems are at various stages of design as defined by the project, namely, preliminary design, final design and formal reviews. Significant progresses have been made in the prototypes studies and design validations, such as the CL and cold circulators. While one of the prototype CL is already tested, the other one is in manufacturing phase. Performance test of two cold circulators have been completed. Design requirements are unique due the complexity arising from load specifications, layout constraints, regulatory compliance, operating conditions as well as several hundred interfaces. The present status of the project in terms of technical achievements, implications of the changes and the technical management as well as the risk assessment and its mitigation including path forward towards realization is described.

Extended Plate and Beam Wall System: Concept Investigation and Initial Evaluation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wiehagen, J.; Kochkin, V.

A new and innovative High-R wall design, referred to as the Extended Plate & Beam (EP&B), is under development. The EP&B system uniquely integrates foam sheathing insulation with wall framing such that wood structural panels are installed exterior of the foam sheathing, enabling the use of standard practices for installation of drainage plane, windows and doors, claddings, cavity insulation, and the standard exterior foam sheathing installation approach prone to damage of the foam during transportation of prefabricated wall panels. As part of the ongoing work, the EP&B wall system concept has undergone structural verification testing and has been positively vettedmore » by a group of industry stakeholders. Having passed these initial milestone markers, the advanced wall system design has been analyzed to assess cost implications relative to other advanced wall systems, undergone design assessment to develop construction details, and has been evaluated to develop representative prescriptive requirements for the building code. This report summarizes the assessment steps conducted to-date and provides details of the concept development.« less

Extended Plate and Beam Wall System: Concept Investigation and Initial Evaluation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wiehagen, J.; Kochkin, V.

2015-08-01

A new and innovative High-R wall design, referred to as the Extended Plate & Beam (EP&B), is under development. The EP&B system uniquely integrates foam sheathing insulation with wall framing such that wood structural panels are installed exterior of the foam sheathing, enabling the use of standard practices for installation of drainage plane, windows and doors, claddings, cavity insulation, and the standard exterior foam sheathing installation approach prone to damage of the foam during transportation of prefabricated wall panels. As part of the ongoing work, the EP&B wall system concept has undergone structural verification testing and has been positively vettedmore » by a group of industry stakeholders. Having passed these initial milestone markers, the advanced wall system design has been analyzed to assess cost implications relative to other advanced wall systems, undergone design assessment to develop construction details, and has been evaluated to develop representative prescriptive requirements for the building code. This report summarizes the assessment steps conducted to-date and provides details of the concept development.« less

Assessing the role of GPs in Nordic health care systems.

PubMed

Quaye, Randolph K

2016-05-03

Purpose This paper examines the changing role of general practitioners (GPs) in Nordic countries of Sweden, Norway and Denmark. It aims to explore the "gate keeping" role of GPs in the face of current changes in the health care delivery systems in these countries. Design/methodology/approach Data were collected from existing literature, interviews with GPs, hospital specialists and representatives of Danish regions and Norwegian Medical Association. Findings The paper contends that in all these changes, the position of the GPs in the medical division of labor has been strengthened, and patients now have increased and broadened access to choice. Research limitations/implications Health care cost and high cancer mortality rates have forced Nordic countries of Sweden, Norway and Denmark to rethink their health care systems. Several attempts have been made to reduce health care cost through market reform and by strenghtening the position of GPs. The evidence suggests that in Norway and Denmark, right incentives are in place to achieve this goal. Sweden is not far behind. The paper has limitations of a small sample size and an exclusive focus on GPs. Practical implications Anecdotal evidence suggests that physicians are becoming extremely unhappy. Understanding the changing status of primary care physicians will yield valuable information for assessing the effectiveness of Nordic health care delivery systems. Social implications This study has wider implications of how GPs see their role as potential gatekeepers in the Nordic health care systems. The role of GPs is changing as a result of recent health care reforms. Originality/value This paper contends that in Norway and Denmark, right incentives are in place to strengthen the position of GPs.

System-of-Systems Considerations in the Notional Development of a Metropolitan Aerial Transportation System. [Implications as to the Identification of Enabling Technologies and Reference Designs for Extreme Short Haul VTOL Vehicles With Electric Propulsion

NASA Technical Reports Server (NTRS)

Alonso, Juan J.; Arneson, Heather M.; Melton, John E.; Vegh, Michael; Walker, Cedric; Young, Larry A.

2017-01-01

There are substantial future challenges related to sustaining and improving efficient, cost-effective, and environmentally friendly transportation options for urban regions. Over the past several decades there has been a worldwide trend towards increasing urbanization of society. Accompanying this urbanization are increasing surface transportation infrastructure costs and, despite public infrastructure investments, increasing surface transportation "gridlock." In addition to this global urbanization trend, there has been a substantial increase in concern regarding energy sustainability, fossil fuel emissions, and the potential implications of global climate change. A recently completed study investigated the feasibility of an aviation solution for future urban transportation (refs. 1, 2). Such an aerial transportation system could ideally address some of the above noted concerns related to urbanization, transportation gridlock, and fossil fuel emissions (ref. 3). A metro/regional aerial transportation system could also provide enhanced transportation flexibility to accommodate extraordinary events such as surface (rail/road) transportation network disruptions and emergency/disaster relief responses.

Vitamin D in the Pathophysiology of Hypertension, Kidney Disease, and Diabetes: Examining the Relationship Between Vitamin D and the Renin-Angiotensin System in Human Diseases

PubMed Central

Vaidya, Anand; Williams, Jonathan S.

2011-01-01

Objective Vitamin D has been implicated in the pathophysiology of extra-skeletal conditions such as hypertension, kidney disease, and diabetes, via its ability to negatively regulate the renin-angiotensin system (RAS). This article reviews the evidence supporting a link between vitamin D and the RAS in these conditions, with specific emphasis on translational observations and their limitations. Methods Literature review of animal and human studies evaluating the role of vitamin D in hypertension, kidney disease, and diabetes. Results Excess activity of the RAS has been implicated in the pathogenesis of hypertension, chronic kidney disease, decreased insulin secretion, and insulin resistance. Animal studies provide strong support for 1,25(OH)2D mediated down-regulation of renin expression and RAS activity via its interaction with the vitamin D receptor. Furthermore, the activity of vitamin D metabolites in animals is associated with reductions in blood pressure, proteinuria and renal injury, and with improved β–cell function. Many observational, and a few interventional, studies in humans have supported these findings; however, there is a lack of well designed prospective human interventional studies to definitively assess clinical outcomes. Conclusion Animal studies implicate vitamin D receptor agonist therapy to lower RAS activity as a potential method to reduce the risk of hypertension, kidney disease, and diabetes. There is a need for more well designed prospective interventional studies to validate this hypothesis in human clinical outcomes. PMID:22075270

Satellite power system (SPS) military implications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bain, C.N.

1978-10-01

This study was conducted to examine military implications of the NASA Reference SPS and to identify important military related study tasks that could be completed during fiscal year 1979. Primary areas of investigation were the potential of the SPS as a weapon, for supporting U.S. military preparedness and for affecting international relations. In addition, the SPS's relative vulnerability to overt military action, terrorist attacks, and sabotage was considered. The SPS could act as an electronic warfare weapon and, with modification, as a marginally effective energy-beaming weapon. The system could support military preparedness by providing energy for a strong and stablemore » U.S. economy and by providing a powered platform for military systems, system segments, and operations. The SPS would be vulnerable to military action, terrorism and sabotage unless hardened against these attacks by design, security, and a self-defense system. Tasks identified for completion in fiscal year 1979 include (a) a detailed vulnerability study, (b) evaluation of an SPS self-defense system concept, (c) determination of the effect of SPS flexibility to deliver different sized electrical loads on the ability to gain SPS support from individual nations, and (d) investigation of the effect of SPS deployment schedule on obtaining needed agreements, providing security, and controlling risks of armed conflict. A fifth and long-term task would consist of a worldwide survey identifiying military implications of the SPS that result from the specific requirements of potential SPS power customers.« less

Design, Modeling and Simulations in the RACE Project: Preliminary study for the development of a transport line

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maidana, C. O.; Hunt, A. W.; Idaho State University, Department of Physics, PO Box 8106, Pocatello, ID 83209

2007-02-12

As part of the Reactor Accelerator Coupling Experiment (RACE) a set of preliminary studies were conducted to design a transport beam line that could bring a 25 MeV electron beam from a Linear Accelerator to a neutron-producing target inside a subcritical system. Because of the relatively low energy beam, the beam size and a relatively long beam line (implicating a possible divergence problem) different parameters and models were studied before a final design could be submitted for assembly. This report shows the first results obtained from different simulations of the transport line optics and dynamics.

Design Aspects of the VLBI2010 System - Progress Report of the IVS VLBI2010 Committee

NASA Technical Reports Server (NTRS)

Petrachenko, Bill; Niell, Arthur; Behrend, Dirk; Corey, Brian; Boehm, Johannes; Chralot, Patrick; Collioud, Arnaud; Gipson, John; Haas, Ruediger; Hobiger, Thomas;

Civil Uses of Remotely Piloted Aircraft

NASA Technical Reports Server (NTRS)

Aderhold, J. R.; Gordon, G.; Scott, G. W.

1976-01-01

The economic, technical, and environmental implications of remotely piloted vehicles (RVP) are examined. The time frame is 1980-85. Representative uses are selected; detailed functional and performance requirements are derived for RPV systems; and conceptual system designs are devised. Total system cost comparisons are made with non-RPV alternatives. The potential market demand for RPV systems is estimated. Environmental and safety requirements are examined, and legal and regulatory concerns are identified. A potential demand for 2,000-11,000 RVP systems is estimated. Typical cost savings of 25 to 35% compared to non-RPV alternatives are determined. There appear to be no environmental problems, and the safety issue appears manageable.

Requirements for migration of NSSD code systems from LTSS to NLTSS

NASA Technical Reports Server (NTRS)

Pratt, M.

1984-01-01

The purpose of this document is to address the requirements necessary for a successful conversion of the Nuclear Design (ND) application code systems to the NLTSS environment. The ND application code system community can be characterized as large-scale scientific computation carried out on supercomputers. NLTSS is a distributed operating system being developed at LLNL to replace the LTSS system currently in use. The implications of change are examined including a description of the computational environment and users in ND. The discussion then turns to requirements, first in a general way, followed by specific requirements, including a proposal for managing the transition.

Bureaucracy, professionalization and school centred innovation strategies

NASA Astrophysics Data System (ADS)

Morris, Paul

1990-03-01

This paper examines an attempt to promote a school centred innovation strategy within a highly centralized educational system. The School Based Curriculum Project Scheme, which was introduced into Hong Kong in 1988, is analysed in terms of a professional-bureaucratic dichotomy. It is argued that the operational details of the scheme are designed to satisfy a range of bureaucratic concerns and these are not conducive to promoting the professional work ethic which is required for school centred innovation. Finally the paper identifies the implications which arise for policies designed to promote curriculum innovation.

Handling Qualities Implications for Crewed Spacecraft Operations

NASA Technical Reports Server (NTRS)

Bailey, Randall E.; Jackson, E. Bruce; Arthur, J. J.

2012-01-01

Abstract Handling qualities embody those qualities or characteristics of an aircraft that govern the ease and precision with which a pilot is able to perform the tasks required in support of an aircraft role. These same qualities are as critical, if not more so, in the operation of spacecraft. A research, development, test, and evaluation process was put into effect to identify, understand, and interpret the engineering and human factors principles which govern the pilot-vehicle dynamic system as they pertain to space exploration missions and tasks. Toward this objective, piloted simulations were conducted at the NASA Langley Research Center and Ames Research Center for earth-orbit proximity operations and docking and lunar landing. These works provide broad guidelines for the design of spacecraft to exhibit excellent handling characteristics. In particular, this work demonstrates how handling qualities include much more than just stability and control characteristics of a spacecraft or aircraft. Handling qualities are affected by all aspects of the pilot-vehicle dynamic system, including the motion, visual and aural cues of the vehicle response as the pilot performs the required operation or task. A holistic approach to spacecraft design, including the use of manual control, automatic control, and pilot intervention/supervision is described. The handling qualities implications of design decisions are demonstrated using these pilot-in-the-loop evaluations of docking operations and lunar landings.

Organizational and technological correlates of nurses’ trust in a smart IV pump

PubMed Central

Montague, Enid; Asan, Onur; Chiou, Erin

2013-01-01

The aim of this study was to understand technology and system characteristics that contribute to nurses’ ratings of trust in a smart IV pump. Nurse’s trust in new technologies can influence how technologies are used. Trust in technology is defined as a person’s belief that a technology will not fail them. Potential outcomes of trust in technology are appropriate trust, over trust, distrust, and mistrust. Trust in technology is also related to several use specific outcomes, including appropriate use and inappropriate use such as over reliance, disuse or rejection, or misuse. Understanding trust in relation to outcomes can contribute to designs that facilitate appropriate trust in new technologies. A survey was completed by 391 nurses a year after the implementation of a new smart IV pump. The survey assessed trust in the IV pump and other elements of the sociotechnical system, individual characteristics, technology characteristics and organizational characteristics. Results show perceptions of usefulness, safety, ease of use and usability are related to ratings of trust in smart IV pumps. Other work system factors such as perception of work environment, age, experience, quality of work, and perception of work performance are also related to ratings of trust. Nurses’ trust in smart IV pumps is influenced by both characteristics of the technology and the sociotechnical system. Findings from this research have implications for the design of future smart IV pumps and health systems. Recommendations for appropriately trustworthy smart IV pumps are discussed. Findings also have implications for how trust in health technologies can be measured and conceptualized in complex sociotechnical systems. PMID:23321482

Comparison of freezing control strategies for residential air-to-air heat recovery ventilators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Phillips, E.G.; Bradley, L.C.; Chant, R.E.

1989-01-01

A comparison of the energy performance of defrost and frost control strategies for residential air-to-air heat recovery ventilators (HRV) has been carried out by using computer simulations for various climatic conditions. This paper discusses the results and conclusions from the comparisons and their implications for the heat recovery ventilator manufacturers and system designers.

Field Dependence-Independence as Visuospatial and Executive Functioning in Working Memory: Implications for Instructional Systems Design and Research

ERIC Educational Resources Information Center

Rittschof, Kent A.

2010-01-01

Field dependence-independence (FDI) has long been conceptualized and discussed as a cognitive style relevant to numerous educational approaches and outcomes. However, the FDI construct is most often measured as a cognitive ability, as opposed to a style, using instruments such as the Group-Embedded Figures test (GEFT) or the Hidden Figures Test…

The Scaled Arrival of K-12 Online Education: Emerging Realities and Implications for the Future of Education

ERIC Educational Resources Information Center

Basham, James D.; Smith, Sean J.; Greer, Diana L.; Marino, Matthew T.

2013-01-01

This article examines the complex array of variables and implementation models that must be accounted for during the pivot from a purely brick-and-mortar educational system to one that makes use of both virtual and blended environments. The authors call for enhanced emphasis on instructional goals and design principles, rather than available…

Disturbances and structural development of natural forest ecosystems with silvicultural implications, using Douglas-fir forests as an example.

Treesearch

J.F. Franklin; T.A. Spies; R.V. Pelt; A.B. Carey; D.A. Thornburgh; D.R. Berg; D.B. Lindenmayer; M.E. Harmon; W.S. Keeton; D.C. Shaw; K. Bible; J. Chen

2002-01-01

Forest managers need a comprehensive scientific understanding of natural stand development processes when designing silvicultural systems that integrate ecological and economic objectives, including a better appreciation of the nature of disturbance regimes and the biological legacies, such as live trees, snags, and logs, that they leave behind. Most conceptual forest...

An Assessment of Feedback Procedures and Information Provided to Instructors within Computer Managed Learning Environments--Implications for Instruction and Software Redesign.

ERIC Educational Resources Information Center

Kotesky, Arturo A.

Feedback procedures and information provided to instructors within computer managed learning environments were assessed to determine current usefulness and meaningfulness to users, and to present the design of a different instructor feedback instrument. Kaufman's system model was applied to accomplish the needs assessment phase of the study; and…

An overview of measurement solutions for digital systems

NASA Astrophysics Data System (ADS)

Lemke, D.

An overview of digital measurement solutions is presented. A summary of the digital instrumentation that is currently available on the commercial market is given. The technology trends that are driving commercial instrumentation suppliers to provide newer and more advanced features and better measurement solutions for the future is reviewed. The implications of developments in design automation for electrical engineers is discussed.

C+C Fusion Cross Sections Measurements for Nuclear Astrophysics

DOE PAGES

Almaraz-Calderon, S.; Carnelli, P. F. F.; Rehm, K. E.; ...

2015-06-02

Total fusion cross section of carbon isotopes were obtained using the newly developed MUSIC detector. MUSIC is a highly efficient, active target-detector system designed to measure fusion excitation functions with radioactive beams. The present measurements are relevant for understanding x-ray superbursts. The results of the first MUSIC campaign as well as the astrophysical implications are presented in this work.

C+C Fusion Cross Sections Measurements for Nuclear Astrophysics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Almaraz-Calderon, S.; Carnelli, P. F. F.; Rehm, K. E.

Total fusion cross section of carbon isotopes were obtained using the newly developed MUSIC detector. MUSIC is a highly efficient, active target-detector system designed to measure fusion excitation functions with radioactive beams. The present measurements are relevant for understanding x-ray superbursts. The results of the first MUSIC campaign as well as the astrophysical implications are presented in this work.

Implications of QRIS Design for the Distribution of Program Ratings and Linkages between Ratings and Observed Quality. OPRE Research Brief 2014-33

ERIC Educational Resources Information Center

Tout, Kathryn; Chien, Nina; Rothenberg, Laura; Li, Weilin

2014-01-01

This Brief compares three hypothetical Quality Rating and Improvement Systems (QRIS) that use different rating structures: block, points, and hybrid. Because the quality standards in the hypothetical QRIS are held relatively constant across structures, analyses can be conducted to determine how structure relates to key QRIS outcomes. Three…

Developmental biology of the innate immune response: implications for neonatal and infant vaccine development.

PubMed

Philbin, Victoria Jane; Levy, Ofer

2009-05-01

Molecular characterization of mechanisms by which human pattern recognition receptors (PRRs) detect danger signals has greatly expanded our understanding of the innate immune system. PRRs include Toll-like receptors, nucleotide oligomerization domain-like receptors, retinoic acid inducible gene-like receptors, and C-type lectin receptors. Characterization of the developmental expression of these systems in the fetus, newborn, and infant is incomplete but has yielded important insights into neonatal susceptibility to infection. Activation of PRRs on antigen-presenting cells enhances costimulatory function, and thus PRR agonists are potential vaccine adjuvants, some of which are already in clinical use. Thus, study of PRRs has also revealed how previously mysterious immunomodulators are able to mediate their actions, including the vaccine adjuvant aluminum hydroxide that activates a cytosolic protein complex known as the Nacht domain leucine-rich repeat and pyrin domain-containing protein 3 inflammasome leading to interleukin-1beta production. Progress in characterizing PRRs is thus informing and expanding the design of improved adjuvants. This review summarizes recent developments in the field of innate immunity emphasizing developmental expression in the fetus, newborn, and infant and its implications for the design of more effective neonatal and infant vaccines.

Informing education policy in Afghanistan: Using design of experiments and data envelopment analysis to provide transparency in complex simulation

NASA Astrophysics Data System (ADS)

Marlin, Benjamin

Education planning provides the policy maker and the decision maker a logical framework in which to develop and implement education policy. At the international level, education planning is often confounded by both internal and external complexities, making the development of education policy difficult. This research presents a discrete event simulation in which individual students and teachers flow through the system across a variable time horizon. This simulation is then used with advancements in design of experiments, multivariate statistical analysis, and data envelopment analysis, to provide a methodology designed to assist the international education planning community. We propose that this methodology will provide the education planner with insights into the complexity of the education system, the effects of both endogenous and exogenous factors upon the system, and the implications of policies as they pertain to potential futures of the system. We do this recognizing that there are multiple actors and stochastic events in play, which although cannot be accurately forecasted, must be accounted for within the education model. To both test the implementation and usefulness of such a model and to prove its relevance, we chose the Afghan education system as the focal point of this research. The Afghan education system is a complex, real world system with competing actors, dynamic requirements, and ambiguous states. At the time of this writing, Afghanistan is at a pivotal point as a nation, and has been the recipient of a tremendous amount of international support and attention. Finally, Afghanistan is a fragile state, and the proliferation of the current disparity in education across gender, districts, and ethnicity could provide the catalyst to drive the country into hostility. In order to prevent the failure of the current government, it is essential that the education system is able to meet the demands of the Afghan people. This work provides insights into the Afghan education system, to include implications of security, the potential effects of societal issues, and prescriptive policy options. In using the proposed methodology, we provide justification for the future use of larger complex simulations in education planning |--- especially when said simulation is integrated with efficient design of experiments and data envelopment analysis.

Characterizing output bottlenecks in a supercomputer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xie, Bing; Chase, Jeffrey; Dillow, David A

2012-01-01

Supercomputer I/O loads are often dominated by writes. HPC (High Performance Computing) file systems are designed to absorb these bursty outputs at high bandwidth through massive parallelism. However, the delivered write bandwidth often falls well below the peak. This paper characterizes the data absorption behavior of a center-wide shared Lustre parallel file system on the Jaguar supercomputer. We use a statistical methodology to address the challenges of accurately measuring a shared machine under production load and to obtain the distribution of bandwidth across samples of compute nodes, storage targets, and time intervals. We observe and quantify limitations from competing traffic,more » contention on storage servers and I/O routers, concurrency limitations in the client compute node operating systems, and the impact of variance (stragglers) on coupled output such as striping. We then examine the implications of our results for application performance and the design of I/O middleware systems on shared supercomputers.« less

Extracellular control of intracellular drug release for enhanced safety of anti-cancer chemotherapy

NASA Astrophysics Data System (ADS)

Zhu, Qian; Qi, Haixia; Long, Ziyan; Liu, Shang; Huang, Zhen; Zhang, Junfeng; Wang, Chunming; Dong, Lei

2016-06-01

The difficulty of controlling drug release at an intracellular level remains a key challenge for maximising drug safety and efficacy. We demonstrate herein a new, efficient and convenient approach to extracellularly control the intracellular release of doxorubicin (DOX), by designing a delivery system that harnesses the interactions between the system and a particular set of cellular machinery. By simply adding a small-molecule chemical into the cell medium, we could lower the release rate of DOX in the cytosol, and thereby increase its accumulation in the nuclei while decreasing its presence at mitochondria. Delivery of DOX with this system effectively prevented DOX-induced mitochondria damage that is the main mechanism of its toxicity, while exerting the maximum efficacy of this anti-cancer chemotherapeutic agent. The present study sheds light on the design of drug delivery systems for extracellular control of intracellular drug delivery, with immediate therapeutic implications.

Three-terminal quantum-dot thermal management devices

NASA Astrophysics Data System (ADS)

Zhang, Yanchao; Zhang, Xin; Ye, Zhuolin; Lin, Guoxing; Chen, Jincan

2017-04-01

We theoretically demonstrate that the heat flows can be manipulated by designing a three-terminal quantum-dot system consisting of three Coulomb-coupled quantum dots connected to respective reservoirs. In this structure, the electron transport between the quantum dots is forbidden, but the heat transport is allowed by the Coulomb interaction to transmit heat between the reservoirs with a temperature difference. We show that such a system is capable of performing thermal management operations, such as heat flow swap, thermal switch, and heat path selector. An important thermal rectifier, i.e., a thermal diode, can be implemented separately in two different paths. The asymmetric configuration of a quantum-dot system is a necessary condition for thermal management operations in practical applications. These results should have important implications in providing the design principle for quantum-dot thermal management devices and may open up potential applications for the thermal management of quantum-dot systems at the nanoscale.

Some design constraints required for the use of generic software in embedded systems: Packages which manage abstract dynamic structures without the need for garbage collection

NASA Technical Reports Server (NTRS)

Johnson, Charles S.

1986-01-01

The embedded systems running real-time applications, for which Ada was designed, require their own mechanisms for the management of dynamically allocated storage. There is a need for packages which manage their own internalo structures to control their deallocation as well, due to the performance implications of garbage collection by the KAPSE. This places a requirement upon the design of generic packages which manage generically structured private types built-up from application-defined input types. These kinds of generic packages should figure greatly in the development of lower-level software such as operating systems, schedulers, controllers, and device driver; and will manage structures such as queues, stacks, link-lists, files, and binary multary (hierarchical) trees. Controlled to prevent inadvertent de-designation of dynamic elements, which is implicit in the assignment operation A study was made of the use of limited private type, in solving the problems of controlling the accumulation of anonymous, detached objects in running systems. The use of deallocator prodecures for run-down of application-defined input types during deallocation operations during satellites.

Learning design in healthcare education.

PubMed

Ellaway, Rachel; Dalziel, James; Dalziel, Bronwen

2008-01-01

Emerging from ongoing work into educational modelling languages, learning design principles and the IMS Learning Design framework provide formal ways to annotate and record educational activities. Once educational activities have been encoded they can be played, replayed, adopted, shared, and analysed, thereby reifying much that is otherwise lost in face-to-face teaching. The use of learning design tools, including the free and open source LAMS system (www.lamsfoundation.org), allow practitioners to experiment with learning design approaches in their own teaching, both in terms of creating and encoding their own designs and playing, adapting and analysing designs from other teachers either from within or outside a particular field or subject area. This paper reviews the key issues associated with designing for learning in the context of healthcare education, some of the themes and approaches already in development or use, and the implications of this approach on the practice and theory of healthcare education.

Dissipative Prototyping Methods: A Manifesto

NASA Astrophysics Data System (ADS)

Beesley, P.

Taking a designer's unique perspective using examples of practice in experimental installation and digital protoyping, this manifesto acts as provocation for change and unlocking new potential by encouraging changes of perspective about the material realm. Diffusive form-language is proposed as a paradigm for architectural design. This method of design is applied through 3D printing and related digital fabrication methods, offering new qualities that can be implemented in design of realms including present earth and future interplanetary environments. A paradigm shift is encouraged by questioning conventional notions of geometry that minimize interfaces and by proposing the alternatives of maximized interfaces formed by effusive kinds of formal composition. A series of projects from the Canadian research studio of the Hylozoic Architecture group are described, providing examples of component design methods employing diffusive forms within combinations of tension-integrity structural systems integrated with hybrid metabolisms employing synthetic biology. Cultural implications are also discussed, drawing from architectural theory and natural philosophy. The conclusion of this paper suggests that the practice of diffusive prototyping can offer formative strategies contributing to design of future living systems.

A numerical study of mixing in supersonic combustors with hypermixing injectors

NASA Technical Reports Server (NTRS)

Lee, J.

1993-01-01

A numerical study was conducted to evaluate the performance of wall mounted fuel-injectors designed for potential Supersonic Combustion Ramjet (SCRAM-jet) engine applications. The focus of this investigation was to numerically simulate existing combustor designs for the purpose of validating the numerical technique and the physical models developed. Three different injector designs of varying complexity were studied to fully understand the computational implications involved in accurate predictions. A dual transverse injection system and two streamwise injector designs were studied. The streamwise injectors were designed with swept ramps to enhance fuel-air mixing and combustion characteristics at supersonic speeds without the large flow blockage and drag contribution of the transverse injection system. For this study, the Mass-Average Navier-Stokes equations and the chemical species continuity equations were solved. The computations were performed using a finite-volume implicit numerical technique and multiple block structured grid system. The interfaces of the multiple block structured grid systems were numerically resolved using the flux-conservative technique. Detailed comparisons between the computations and existing experimental data are presented. These comparisons show that numerical predictions are in agreement with the experimental data. These comparisons also show that a number of turbulence model improvements are needed for accurate combustor flowfield predictions.

A numerical study of mixing in supersonic combustors with hypermixing injectors

NASA Technical Reports Server (NTRS)

Lee, J.

1992-01-01

A numerical study was conducted to evaluate the performance of wall mounted fuel-injectors designed for potential Supersonic Combustion Ramjet (SCRAM-jet) engine applications. The focus of this investigation was to numerically simulate existing combustor designs for the purpose of validating the numerical technique and the physical models developed. Three different injector designs of varying complexity were studied to fully understand the computational implications involved in accurate predictions. A dual transverse injection system and two streamwise injector designs were studied. The streamwise injectors were designed with swept ramps to enhance fuel-air mixing and combustion characteristics at supersonic speeds without the large flow blockage and drag contribution of the transverse injection system. For this study, the Mass-Averaged Navier-Stokes equations and the chemical species continuity equations were solved. The computations were performed using a finite-volume implicit numerical technique and multiple block structured grid system. The interfaces of the multiple block structured grid systems were numerically resolved using the flux-conservative technique. Detailed comparisons between the computations and existing experimental data are presented. These comparisons show that numerical predictions are in agreement with the experimental data. These comparisons also show that a number of turbulence model improvements are needed for accurate combustor flowfield predictions.

A systems engineering perspective on the human-centered design of health information systems.

PubMed

Samaras, George M; Horst, Richard L

2005-02-01

The discipline of systems engineering, over the past five decades, has used a structured systematic approach to managing the "cradle to grave" development of products and processes. While elements of this approach are typically used to guide the development of information systems that instantiate a significant user interface, it appears to be rare for the entire process to be implemented. In fact, a number of authors have put forth development lifecycle models that are subsets of the classical systems engineering method, but fail to include steps such as incremental hazard analysis and post-deployment corrective and preventative actions. In that most health information systems have safety implications, we argue that the design and development of such systems would benefit by implementing this systems engineering approach in full. Particularly with regard to bringing a human-centered perspective to the formulation of system requirements and the configuration of effective user interfaces, this classical systems engineering method provides an excellent framework for incorporating human factors (ergonomics) knowledge and integrating ergonomists in the interdisciplinary development of health information systems.

Is Model-Based Development a Favorable Approach for Complex and Safety-Critical Computer Systems on Commercial Aircraft?

NASA Technical Reports Server (NTRS)

Torres-Pomales, Wilfredo

2014-01-01

A system is safety-critical if its failure can endanger human life or cause significant damage to property or the environment. State-of-the-art computer systems on commercial aircraft are highly complex, software-intensive, functionally integrated, and network-centric systems of systems. Ensuring that such systems are safe and comply with existing safety regulations is costly and time-consuming as the level of rigor in the development process, especially the validation and verification activities, is determined by considerations of system complexity and safety criticality. A significant degree of care and deep insight into the operational principles of these systems is required to ensure adequate coverage of all design implications relevant to system safety. Model-based development methodologies, methods, tools, and techniques facilitate collaboration and enable the use of common design artifacts among groups dealing with different aspects of the development of a system. This paper examines the application of model-based development to complex and safety-critical aircraft computer systems. Benefits and detriments are identified and an overall assessment of the approach is given.

Allometric scaling law in a simple oxygen exchanging network: possible implications on the biological allometric scaling laws.

PubMed

Santillán, Moisés

2003-07-21

A simple model of an oxygen exchanging network is presented and studied. This network's task is to transfer a given oxygen rate from a source to an oxygen consuming system. It consists of a pipeline, that interconnects the oxygen consuming system and the reservoir and of a fluid, the active oxygen transporting element, moving through the pipeline. The network optimal design (total pipeline surface) and dynamics (volumetric flow of the oxygen transporting fluid), which minimize the energy rate expended in moving the fluid, are calculated in terms of the oxygen exchange rate, the pipeline length, and the pipeline cross-section. After the oxygen exchanging network is optimized, the energy converting system is shown to satisfy a 3/4-like allometric scaling law, based upon the assumption that its performance regime is scale invariant as well as on some feasible geometric scaling assumptions. Finally, the possible implications of this result on the allometric scaling properties observed elsewhere in living beings are discussed.

Informal Learning in Professional and Personal Life: Implications for Instructional Design and Performance Improvement

ERIC Educational Resources Information Center

Klein, James D.; Moore, Alison L.

2016-01-01

This article focuses on informal learning and its implications for instructional design and performance improvement. The authors begin by sharing a story of how a novice instructional designer employs informal learning strategies in her professional and personal life. Next, they offer a definition of informal learning that encompasses both…

Big Data in Designing Clinical Trials: Opportunities and Challenges

PubMed Central

Mayo, Charles S.; Matuszak, Martha M.; Schipper, Matthew J.; Jolly, Shruti; Hayman, James A.; Ten Haken, Randall K.

2017-01-01

Emergence of big data analytics resource systems (BDARSs) as a part of routine practice in Radiation Oncology is on the horizon. Gradually, individual researchers, vendors, and professional societies are leading initiatives to create and demonstrate use of automated systems. What are the implications for design of clinical trials, as these systems emerge? Gold standard, randomized controlled trials (RCTs) have high internal validity for the patients and settings fitting constraints of the trial, but also have limitations including: reproducibility, generalizability to routine practice, infrequent external validation, selection bias, characterization of confounding factors, ethics, and use for rare events. BDARS present opportunities to augment and extend RCTs. Preliminary modeling using single- and muti-institutional BDARS may lead to better design and less cost. Standardizations in data elements, clinical processes, and nomenclatures used to decrease variability and increase veracity needed for automation and multi-institutional data pooling in BDARS also support ability to add clinical validation phases to clinical trial design and increase participation. However, volume and variety in BDARS present other technical, policy, and conceptual challenges including applicable statistical concepts, cloud-based technologies. In this summary, we will examine both the opportunities and the challenges for use of big data in design of clinical trials. PMID:28913177

Big Data in Designing Clinical Trials: Opportunities and Challenges.

PubMed

Mayo, Charles S; Matuszak, Martha M; Schipper, Matthew J; Jolly, Shruti; Hayman, James A; Ten Haken, Randall K

2017-01-01

Emergence of big data analytics resource systems (BDARSs) as a part of routine practice in Radiation Oncology is on the horizon. Gradually, individual researchers, vendors, and professional societies are leading initiatives to create and demonstrate use of automated systems. What are the implications for design of clinical trials, as these systems emerge? Gold standard, randomized controlled trials (RCTs) have high internal validity for the patients and settings fitting constraints of the trial, but also have limitations including: reproducibility, generalizability to routine practice, infrequent external validation, selection bias, characterization of confounding factors, ethics, and use for rare events. BDARS present opportunities to augment and extend RCTs. Preliminary modeling using single- and muti-institutional BDARS may lead to better design and less cost. Standardizations in data elements, clinical processes, and nomenclatures used to decrease variability and increase veracity needed for automation and multi-institutional data pooling in BDARS also support ability to add clinical validation phases to clinical trial design and increase participation. However, volume and variety in BDARS present other technical, policy, and conceptual challenges including applicable statistical concepts, cloud-based technologies. In this summary, we will examine both the opportunities and the challenges for use of big data in design of clinical trials.

System Design under Uncertainty: Evolutionary Optimization of the Gravity Probe-B Spacecraft

NASA Technical Reports Server (NTRS)

Pullen, Samuel P.; Parkinson, Bradford W.

1994-01-01

This paper discusses the application of evolutionary random-search algorithms (Simulated Annealing and Genetic Algorithms) to the problem of spacecraft design under performance uncertainty. Traditionally, spacecraft performance uncertainty has been measured by reliability. Published algorithms for reliability optimization are seldom used in practice because they oversimplify reality. The algorithm developed here uses random-search optimization to allow us to model the problem more realistically. Monte Carlo simulations are used to evaluate the objective function for each trial design solution. These methods have been applied to the Gravity Probe-B (GP-B) spacecraft being developed at Stanford University for launch in 1999, Results of the algorithm developed here for GP-13 are shown, and their implications for design optimization by evolutionary algorithms are discussed.

Humans: still vital after all these years of automation.

PubMed

Parasuraman, Raja; Wickens, Christopher D

2008-06-01

The authors discuss empirical studies of human-automation interaction and their implications for automation design. Automation is prevalent in safety-critical systems and increasingly in everyday life. Many studies of human performance in automated systems have been conducted over the past 30 years. Developments in three areas are examined: levels and stages of automation, reliance on and compliance with automation, and adaptive automation. Automation applied to information analysis or decision-making functions leads to differential system performance benefits and costs that must be considered in choosing appropriate levels and stages of automation. Human user dependence on automated alerts and advisories reflects two components of operator trust, reliance and compliance, which are in turn determined by the threshold designers use to balance automation misses and false alarms. Finally, adaptive automation can provide additional benefits in balancing workload and maintaining the user's situation awareness, although more research is required to identify when adaptation should be user controlled or system driven. The past three decades of empirical research on humans and automation has provided a strong science base that can be used to guide the design of automated systems. This research can be applied to most current and future automated systems.

The Design and Analysis of Salmonid Tagging Studies in the Columbia Basin : Volume II: Experiment Salmonid Survival with Combined PIT-CWT Tagging.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Newman, Ken

1997-06-01

Experiment designs to estimate the effect of transportation on survival and return rates of Columbia River system salmonids are discussed along with statistical modeling techniques. Besides transportation, river flow and dam spill are necessary components in the design and analysis otherwise questions as to the effects of reservoir drawdowns and increased dam spill may never be satisfactorily answered. Four criteria for comparing different experiment designs are: (1) feasibility, (2) clarity of results, (3) scope of inference, and (4) time to learn. In this report, alternative designs for conducting experimental manipulations of smolt tagging studies to study effects of river operationsmore » such as flow levels, spill fractions, and transporting outmigrating salmonids around dams in the Columbia River system are presented. The principles of study design discussed in this report have broad implications for the many studies proposed to investigate both smolt and adult survival relationships. The concepts are illustrated for the case of the design and analysis of smolt transportation experiments. The merits of proposed transportation studies should be measured relative to these principles of proper statistical design and analysis.« less

Improved estimation of random vibration loads in launch vehicles

NASA Technical Reports Server (NTRS)

Mehta, R.; Erwin, E.; Suryanarayan, S.; Krishna, Murali M. R.

1993-01-01

Random vibration induced load is an important component of the total design load environment for payload and launch vehicle components and their support structures. The current approach to random vibration load estimation is based, particularly at the preliminary design stage, on the use of Miles' equation which assumes a single degree-of-freedom (DOF) system and white noise excitation. This paper examines the implications of the use of multi-DOF system models and response calculation based on numerical integration using the actual excitation spectra for random vibration load estimation. The analytical study presented considers a two-DOF system and brings out the effects of modal mass, damping and frequency ratios on the random vibration load factor. The results indicate that load estimates based on the Miles' equation can be significantly different from the more accurate estimates based on multi-DOF models.

A socio-technical critique of tiered services: implications for interprofessional care.

PubMed

Hood, Rick

2015-01-01

In the health and social care sector, tiered services have become an increasingly influential way of organising professional expertise to address the needs of vulnerable people. Drawing on its application to UK child welfare services, this paper discusses the merits of the tiered model from a socio-technical perspective - an approach that has emerged from the fields of accident analysis and systems design. The main elements of a socio-technical critique are outlined and used to explore how tiered services provide support to families and prevent harm to children. Attention is drawn to the distribution of expertise and resources in a tiered system, and to the role of referral and gate-keeping procedures in dispersing accountability for outcomes. An argument is made for designing systems "against demand", and the paper concludes by discussing some alternative models of multi-agency provision.

Hearing loss and the central auditory system: Implications for hearing aids

NASA Astrophysics Data System (ADS)

Frisina, Robert D.

2003-04-01

Hearing loss can result from disorders or damage to the ear (peripheral auditory system) or the brain (central auditory system). Here, the basic structure and function of the central auditory system will be highlighted as relevant to cases of permanent hearing loss where assistive devices (hearing aids) are called for. The parts of the brain used for hearing are altered in two basic ways in instances of hearing loss: (1) Damage to the ear can reduce the number and nature of input channels that the brainstem receives from the ear, causing plasticity of the central auditory system. This plasticity may partially compensate for the peripheral loss, or add new abnormalities such as distorted speech processing or tinnitus. (2) In some situations, damage to the brain can occur independently of the ear, as may occur in cases of head trauma, tumors or aging. Implications of deficits to the central auditory system for speech perception in noise, hearing aid use and future innovative circuit designs will be provided to set the stage for subsequent presentations in this special educational session. [Work supported by NIA-NIH Grant P01 AG09524 and the International Center for Hearing & Speech Research, Rochester, NY.

Engineering Design of ITER Prototype Fast Plant System Controller

NASA Astrophysics Data System (ADS)

Goncalves, B.; Sousa, J.; Carvalho, B.; Rodrigues, A. P.; Correia, M.; Batista, A.; Vega, J.; Ruiz, M.; Lopez, J. M.; Rojo, R. Castro; Wallander, A.; Utzel, N.; Neto, A.; Alves, D.; Valcarcel, D.

2011-08-01

The ITER control, data access and communication (CODAC) design team identified the need for two types of plant systems. A slow control plant system is based on industrial automation technology with maximum sampling rates below 100 Hz, and a fast control plant system is based on embedded technology with higher sampling rates and more stringent real-time requirements than that required for slow controllers. The latter is applicable to diagnostics and plant systems in closed-control loops whose cycle times are below 1 ms. Fast controllers will be dedicated industrial controllers with the ability to supervise other fast and/or slow controllers, interface to actuators and sensors and, if necessary, high performance networks. Two prototypes of a fast plant system controller specialized for data acquisition and constrained by ITER technological choices are being built using two different form factors. This prototyping activity contributes to the Plant Control Design Handbook effort of standardization, specifically regarding fast controller characteristics. Envisaging a general purpose fast controller design, diagnostic use cases with specific requirements were analyzed and will be presented along with the interface with CODAC and sensors. The requirements and constraints that real-time plasma control imposes on the design were also taken into consideration. Functional specifications and technology neutral architecture, together with its implications on the engineering design, were considered. The detailed engineering design compliant with ITER standards was performed and will be discussed in detail. Emphasis will be given to the integration of the controller in the standard CODAC environment. Requirements for the EPICS IOC providing the interface to the outside world, the prototype decisions on form factor, real-time operating system, and high-performance networks will also be discussed, as well as the requirements for data streaming to CODAC for visualization and archiving.

Reliability considerations of a fuel cell backup power system for telecom applications

NASA Astrophysics Data System (ADS)

Serincan, Mustafa Fazil

2016-03-01

A commercial fuel cell backup power unit is tested in real life operating conditions at a base station of a Turkish telecom operator. The fuel cell system responds to 256 of 260 electric power outages successfully, providing the required power to the base station. Reliability of the fuel cell backup power unit is found to be 98.5% at the system level. On the other hand, a qualitative reliability analysis at the component level is carried out. Implications of the power management algorithm on reliability is discussed. Moreover, integration of the backup power unit to the base station ecosystem is reviewed in the context of reliability. Impact of inverter design on the stability of the output power is outlined. Significant current harmonics are encountered when a generic inverter is used. However, ripples are attenuated significantly when a custom design inverter is used. Further, fault conditions are considered for real world case studies such as running out of hydrogen, a malfunction in the system, or an unprecedented operating scheme. Some design guidelines are suggested for hybridization of the backup power unit for an uninterrupted operation.

Applications of flight control system methods to an advanced combat rotorcraft

NASA Technical Reports Server (NTRS)

Tischler, Mark B.; Fletcher, Jay W.; Morris, Patrick M.; Tucker, George T.

1989-01-01

Advanced flight control system design, analysis, and testing methodologies developed at the Ames Research Center are applied in an analytical and flight test evaluation of the Advanced Digital Optical Control System (ADOCS) demonstrator. The primary objectives are to describe the knowledge gained about the implications of digital flight control system design for rotorcraft, and to illustrate the analysis of the resulting handling-qualities in the context of the proposed new handling-qualities specification for rotorcraft. Topics covered in-depth are digital flight control design and analysis methods, flight testing techniques, ADOCS handling-qualities evaluation results, and correlation of flight test results with analytical models and the proposed handling-qualities specification. The evaluation of the ADOCS demonstrator indicates desirable response characteristics based on equivalent damping and frequency, but undersirably large effective time-delays (exceeding 240 m sec in all axes). Piloted handling-qualities are found to be desirable or adequate for all low, medium, and high pilot gain tasks; but handling-qualities are inadequate for ultra-high gain tasks such as slope and running landings.

Systematic behavior research for understanding consumer decision making.

PubMed

Lin, Chin-Feng

2009-05-01

This study incorporates means-end chain (MEC) theory and dynamic programming for understanding the implications of consumer decision making. The conceptual framework of this study can help programmers design information systems for analyzing consumption behaviors. Such analyses will provide marketers with meaningful information for formulating marketing strategies. The main contributions of this article are as follows: (1) to enable researchers to obtain information for consumer cognitive hierarchies utilizing an information system, (2) to enhance the functions of traditional MEC methodology and provide an integrated method for analyzing consumption information, and (3) to construct an information system for analyzing consumer decision-making processes.

Space safety and rescue 1984-1985

NASA Astrophysics Data System (ADS)

Heath, G. W.

The present conference on spacecraft crew safety and rescue technologies and operations considers safety aspects of Space Shuttle ground processing, the Inmarsat and COSPAS/SARSAT emergency location satellite systems, emergency location and rescue communications using Geosat, the use of the Manned Maneuvering Unit for on-orbit rescue operations, NASA Space Station safety design and operational considerations, and the medico-legal implications of space station operation. Also discussed are the operational and environmental aspects of EPIRBS, mobile satellites for safety and disaster response, Inmarsat's role in the Future Global Maritime Distress and Safety System, and test results of the L-band satellite's EPIRB system.

The relationship between an advanced avionic system architecture and the elimination of the need for an Avionics Intermediate Shop (AIS)

NASA Astrophysics Data System (ADS)

Abraham, S. J.

While Avionics Intermediate Shops (AISs) have in the past been required for military aircraft, the emerging VLSI/VHSIC technology has given rise to the possibility of novel, well partitioned avionics system architectures that obviate the high spare parts costs that formerly prompted and justified the existence of an AIS. Future avionics may therefore be adequately and economically supported by a two-level maintenance system. Algebraic generalizations are presented for the analysis of the spares costs implications of alternative design partitioning schemes for future avionics.

A System for Seismocardiography-Based Identification of Quiescent Heart Phases: Implications for Cardiac Imaging

PubMed Central

Wick, Carson A.; Su, Jin-Jyh; McClellan, James H.; Brand, Oliver; Bhatti, Pamela T.; Buice, Ashley L.; Stillman, Arthur E.; Tang, Xiangyang; Tridandapani, Srini

2013-01-01

Seismocardiography (SCG), a representation of mechanical heart motion, may more accurately determine periods of cardiac quiescence within a cardiac cycle than the electrically derived electrocardiogram (EKG) and, thus, may have implications for gating in cardiac computed tomography. We designed and implemented a system to synchronously acquire echocardiography, EKG, and SCG data. The device was used to study the variability between EKG and SCG and characterize the relationship between the mechanical and electrical activity of the heart. For each cardiac cycle, the feature of the SCG indicating Aortic Valve Closure was identified and its time position with respect to the EKG was observed. This position was found to vary for different heart rates and between two human subjects. A color map showing the magnitude of the SCG acceleration and computed velocity was derived, allowing for direct visualization of quiescent phases of the cardiac cycle with respect to heart rate. PMID:22581141

The computation of induced drag with nonplanar and deformed wakes

NASA Technical Reports Server (NTRS)

Kroo, Ilan; Smith, Stephen

1991-01-01

The classical calculation of inviscid drag, based on far field flow properties, is reexamined with particular attention to the nonlinear effects of wake roll-up. Based on a detailed look at nonlinear, inviscid flow theory, it is concluded that many of the classical, linear results are more general than might have been expected. Departures from the linear theory are identified and design implications are discussed. Results include the following: Wake deformation has little effect on the induced drag of a single element wing, but introduces first order corrections to the induced drag of a multi-element lifting system. Far field Trefftz-plane analysis may be used to estimate the induced drag of lifting systems, even when wake roll-up is considered, but numerical difficulties arise. The implications of several other approximations made in lifting line theory are evaluated by comparison with more refined analyses.

Feasibility of AN Ecrh System for Jet:. Plant Layout, Auxiliaries and Services

NASA Astrophysics Data System (ADS)

Lennholm, M.; Bouquey, F.; Braune, H.; Farthing, J.; Garavaglia, S.; Giruzzi, G.; Granucci, G.; Jennison, M.; Parkin, A.

2011-02-01

A study conducted over the last year to asses the desirability and feasibility of installing an ECRH system on the JET tokamak has concluded that such a system is indeed both desirable and feasible. Details of physics studies, launcher and transmission line design, and power supplies are presented elsewhere in these proceedings. This paper concentrates on the logistical implications of installing this system at JET. The paper addresses issues such as port allocation and plant location. The study has concluded that a new building will be needed to house the ECRH plant. Building layout proposals are presented together with considerations regarding the required auxiliary equipment.

Building and managing high performance, scalable, commodity mass storage systems

NASA Technical Reports Server (NTRS)

Lekashman, John

1998-01-01

The NAS Systems Division has recently embarked on a significant new way of handling the mass storage problem. One of the basic goals of this new development are to build systems at very large capacity and high performance, yet have the advantages of commodity products. The central design philosophy is to build storage systems the way the Internet was built. Competitive, survivable, expandable, and wide open. The thrust of this paper is to describe the motivation for this effort, what we mean by commodity mass storage, what the implications are for a facility that performs such an action, and where we think it will lead.

Forced underwater laminar flows with active magnetohydrodynamic metamaterials

NASA Astrophysics Data System (ADS)

Culver, Dean; Urzhumov, Yaroslav

2017-12-01

Theory and practical implementations for wake-free propulsion systems are proposed and proven with computational fluid dynamic modeling. Introduced earlier, the concept of active hydrodynamic metamaterials is advanced by introducing magnetohydrodynamic metamaterials, structures with custom-designed volumetric distribution of Lorentz forces acting on a conducting fluid. Distributions of volume forces leading to wake-free, laminar flows are designed using multivariate optimization. Theoretical indications are presented that such flows can be sustained at arbitrarily high Reynolds numbers. Moreover, it is shown that in the limit Re ≫102 , a fixed volume force distribution may lead to a forced laminar flow across a wide range of Re numbers, without the need to reconfigure the force-generating metamaterial. Power requirements for such a device are studied as a function of the fluid conductivity. Implications to the design of distributed propulsion systems underwater and in space are discussed.

A proactive approach for managing indoor air quality

DOE Office of Scientific and Technical Information (OSTI.GOV)

Greene, R.E.; Casey, J.M.; Williams, P.L.

1997-11-01

Ventilation and maintenance, followed by psychosocial issues, are the factors most often implicated in indoor air quality (IAQ) investigations. The absence of accepted exposure standards and the presence of a wide variety of building designs, ages, ventilation systems, and usages often make IAQ complaint investigations ineffective. Thus, the best approach to achieving IAQ is to prevent problems from occurring. This paper presents the framework for a proactive approach to managing the causes most often implicated in IAQ investigations. It is the aim of this proactive protocol to provide a cost-effective guide for preventing IAQ problems in nonindustrial settings and inmore » buildings for which there are no current IAQ complaints. The proposed protocol focuses on heating, ventilation, and air-conditioning (HVAC) system maintenance and operation; psychosocial factors; and the handling and investigation of complaints. An IAQ manager is designated to implement and manage the protocol. The HVAC system portion of the protocol focuses on proper maintenance of the components often identified as sources of problems in IAQ studies, documentation of the maintenance procedures, and training of individuals responsible for building maintenance. The protocol addresses the psychosocial factors with an environmental survey that rates the occupants` perceptions of the indoor air to identify potential IAQ problems. The psychosocial portion of the protocol also incorporates occupant education and awareness. Finally, a three-step initial investigation procedure for addressing IAQ problems is presented.« less

Representing situation awareness in collaborative systems: a case study in the energy distribution domain.

PubMed

Salmon, P M; Stanton, N A; Walker, G H; Jenkins, D; Baber, C; McMaster, R

2008-03-01

The concept of distributed situation awareness (DSA) is currently receiving increasing attention from the human factors community. This article investigates DSA in a collaborative real-world industrial setting by discussing the results derived from a recent naturalistic study undertaken within the UK energy distribution domain. The results describe the DSA-related information used by the networks of agents involved in the scenarios analysed, the sharing of this information between the agents and the salience of different information elements used. Thus, the structure, quality and content of each network's DSA is discussed, along with the implications for DSA theory. The findings reinforce the notion that when viewing situation awareness (SA) in collaborative systems, it is useful to focus on the coordinated behaviour of the system itself, rather than on the individual as the unit of analysis and suggest that the findings from such assessments can potentially be used to inform system, procedure and training design. SA is a critical commodity for teams working in industrial systems and systems, procedures and training programmes should be designed to facilitate efficient system SA acquisition and maintenance. This article presents approaches for describing and understanding SA during real-world collaborative tasks, the outputs from which can potentially be used to inform system, training programmes and procedure design.

Organizational and technological correlates of nurses' trust in a smart intravenous pump.

PubMed

Montague, Enid; Asan, Onur; Chiou, Erin

2013-03-01

The aim of this study was to understand technology and system characteristics that contribute to nurses' ratings of trust in a smart intravenous pump. Nurses' trust in new technologies can influence how technologies are used. Trust in technology is defined as a person's belief that a technology will not fail them. Potential outcomes of trust in technology are appropriate trust, overtrust, distrust, and mistrust. Trust in technology is also related to several use-specific outcomes, including appropriate use and inappropriate use such as overreliance, disuse or rejection, or misuse. Understanding trust in relation to outcomes can contribute to designs that facilitate appropriate trust in new technologies. A survey was completed by 391 nurses a year after the implementation of a new smart intravenous pump. The survey assessed trust in the intravenous pump and other elements of the sociotechnical system, individual characteristics, technology characteristics, and organizational characteristics. Results show that perceptions of usefulness, safety, ease of use, and usability are related to ratings of trust in smart intravenous pumps. Other work systemfactors such as perception of work environment, age, experience, quality of work, and perception of work performance are also related to ratings of trust. Nurses' trust in smart intravenous pumps is influenced by both characteristics of the technology and the sociotechnical system. Findings from this research have implications for the design of future smart intravenous pumps and health systems. Recommendations for appropriately trustworthy smart intravenous pumps are discussed. Findings also have implications for how trust in health technologies can be measured and conceptualized in complex sociotechnical systems.

Improving Quality for Child Care Centers in Greater Philadelphia: An Evaluation of Success by 6®. Technical Appendix. Publication #2016-07B

ERIC Educational Resources Information Center

Warner-Richter, Mallory; Lowe, Claire; Tout, Kathryn; Epstein, Dale; Li, Weilin

2016-01-01

The Success By 6® (SB6) initiative is designed to support early care and education centers in improving and sustaining quality in Pennsylvania's Keystone STARS Quality Rating and Improvement System (QRIS). The SB6 evaluation report examines implementation and outcomes. The findings have implications for SB6 continous quality improvement process…

Improving Quality for Child Care Centers in Greater Philadelphia: An Evaluation of Success by 6®. Executive Summary. Publication #2016-07A

ERIC Educational Resources Information Center

Warner-Richter, Mallory; Lowe, Claire; Tout, Kathryn; Epstein, Dale; Li, Weilin

2016-01-01

The Success By 6® (SB6) initiative is designed to support early care and education centers in improving and sustaining quality in Pennsylvania's Keystone STARS Quality Rating and Improvement System (QRIS). The SB6 evaluation report examines implementation and outcomes. The findings have implications for SB6 continous quality improvement process…

[White House Conference on Aging, 1981. Abstracts of the Technical Committee Reports, Mini White House Conference Reports, and State White House Conference Reports.

ERIC Educational Resources Information Center

Cowell, Daniel D.

This collection of abstracts, designed to assist White House Conference on Aging delegates involved with research on aging, presents information from 16 Technical Committee Reports which focus on implications of an age-integrated society, employment, support systems, health issues and services, the family, long-term care, older Americans as a…

Achievement of Abraham Maslow's Needs Hierarchy Theory among Teachers: Implications for Human Resource Management in the Secondary School System in Rivers State

ERIC Educational Resources Information Center

Adiele, E.E.; Abraham, Nath. M.

2013-01-01

The study investigated the achievement of Abraham Maslow's need hierarchy theory among secondary school teachers in Rivers State. A 25-item questionnaire was designed, validated and administered on a sample of 500 teachers drawn from 245 secondary schools in Rivers State. The result revealed that secondary school teachers indicated insignificant…

Just Curious: Children's Use of Digital Reference Services and Implications for School Library Media Specialists. Guest Writer

ERIC Educational Resources Information Center

Silverstein, Joanne

2007-01-01

Kids ask the darndest questions. And sometimes they ask them in the darndest places, including online information systems that were not designed to answer them. There is a reason for this continuing phenomenon, and an important lesson in it for school library media specialists and other educators. To understand the phenomenon at hand, imagine an…

Course Management Systems as Tools for the Creation of Online Learning Environments: Evaluation from a Social Constructivist Perspective and Implications for Their Design

ERIC Educational Resources Information Center

Papastergiou, Marina

2006-01-01

The Internet and the Web offer academic institutions solutions for covering the massive demand for education and transition towards student-centered, social constructivist educational models, in accordance with the demands of the knowledge-based society. This article reports on an investigation aimed at presenting a synthesis of recent research on…

The Power of Femininity: Exploring the Gender and Ethnic Experiences of Muslim Women Who Accessed Supervisory Roles in a Bedouin Society

ERIC Educational Resources Information Center

Quader, Sarab Abu-Rabia; Oplatka, Izhar

2008-01-01

Purpose: The current paper aims to tell the stories of six female supervisors who have successfully managed to access this high-level position in the Bedouin educational system, putting forward some implications for understanding and exploring the lives and career of women in patriarchal, minority groups. Design/methodology/approach: Six female…

Improving Quality for Child Care Centers in Greater Philadelphia: An Evaluation of Success by 6®. Final Report. Publication #2016-07

ERIC Educational Resources Information Center

Warner-Richter, Mallory; Lowe, Claire; Tout, Kathryn; Epstein, Dale; Li, Weilin

2016-01-01

The Success By 6® (SB6) initiative is designed to support early care and education centers in improving and sustaining quality in Pennsylvania's Keystone STARS Quality Rating and Improvement System (QRIS). This SB6 evaluation report examines implementation and outcomes. The findings have implications for SB6 continous quality improvement process…

Usability of patient-centered health IT: mixed-methods usability study of ePill.

PubMed

Schmidt-Kraepelin, Manuel; Dehling, Tobias; Sunyaev, Ali

2014-01-01

To facilitate use of patient-centered health IT applications in everyday life, a high degree of usability is required. Based on the example of a patient-centered web application, we propose a usability study design enabling developers and researchers to assess usability of patient-centered health IT applications and derive implications for their improvement. Our study design integrates tasks that subjects have to process, an associated questionnaire based on Perceived Ease of Use, Perceived Usefulness, Attitude Toward Using, and Behavioral Intention to Use, a System Usability Scale questionnaire, and focus groups. Application of the usability study design demonstrates its feasibility and provides insights for assessment of usability in related projects in research and practice.

Results of solar electric thrust vector control system design, development and tests

NASA Technical Reports Server (NTRS)

Fleischer, G. E.

1973-01-01

Efforts to develop and test a thrust vector control system TVCS for a solar-energy-powered ion engine array are described. The results of solar electric propulsion system technology (SEPST) III real-time tests of present versions of TVCS hardware in combination with computer-simulated attitude dynamics of a solar electric multi-mission spacecraft (SEMMS) Phase A-type spacecraft configuration are summarized. Work on an improved solar electric TVCS, based on the use of a state estimator, is described. SEPST III tests of TVCS hardware have generally proved successful and dynamic response of the system is close to predictions. It appears that, if TVCS electronic hardware can be effectively replaced by control computer software, a significant advantage in control capability and flexibility can be gained in future developmental testing, with practical implications for flight systems as well. Finally, it is concluded from computer simulations that TVCS stabilization using rate estimation promises a substantial performance improvement over the present design.

Remotely manned systems: Exploration and operation in space; Proceedings of the First National Conference, California Institute of Technology, Pasadena, Calif., September 13-15, 1972.

NASA Technical Reports Server (NTRS)

Heer, E.

1973-01-01

Free-flying teleoperator systems are discussed, giving attention to earth-orbit mission considerations and Space Tug requirements, free-flying teleoperator requirements and conceptual design, system requirements for a free-flying teleoperator to despin, and the experimental evaluation of remote manipulator systems. Shuttle-Attached Manipulator Systems are considered, together with remote surface vehicle systems, manipulator systems technology, remote sensor and display technology, the man-machine interface, and control and machine intelligence. Nonspace applications are also explored, taking into account implications of nonspace applications, naval applications of remote manipulators, and hand tools and mechanical accessories for a deep submersible. Individual items are announced in this issue.

Impact of speech presentation level on cognitive task performance: implications for auditory display design.

PubMed

Baldwin, Carryl L; Struckman-Johnson, David

2002-01-15

Speech displays and verbal response technologies are increasingly being used in complex, high workload environments that require the simultaneous performance of visual and manual tasks. Examples of such environments include the flight decks of modern aircraft, advanced transport telematics systems providing invehicle route guidance and navigational information and mobile communication equipment in emergency and public safety vehicles. Previous research has established an optimum range for speech intelligibility. However, the potential for variations in presentation levels within this range to affect attentional resources and cognitive processing of speech material has not been examined previously. Results of the current experimental investigation demonstrate that as presentation level increases within this 'optimum' range, participants in high workload situations make fewer sentence-processing errors and generally respond faster. Processing errors were more sensitive to changes in presentation level than were measures of reaction time. Implications of these findings are discussed in terms of their application for the design of speech communications displays in complex multi-task environments.

A framework for analyzing the cognitive complexity of computer-assisted clinical ordering.

PubMed

Horsky, Jan; Kaufman, David R; Oppenheim, Michael I; Patel, Vimla L

2003-01-01

Computer-assisted provider order entry is a technology that is designed to expedite medical ordering and to reduce the frequency of preventable errors. This paper presents a multifaceted cognitive methodology for the characterization of cognitive demands of a medical information system. Our investigation was informed by the distributed resources (DR) model, a novel approach designed to describe the dimensions of user interfaces that introduce unnecessary cognitive complexity. This method evaluates the relative distribution of external (system) and internal (user) representations embodied in system interaction. We conducted an expert walkthrough evaluation of a commercial order entry system, followed by a simulated clinical ordering task performed by seven clinicians. The DR model was employed to explain variation in user performance and to characterize the relationship of resource distribution and ordering errors. The analysis revealed that the configuration of resources in this ordering application placed unnecessarily heavy cognitive demands on the user, especially on those who lacked a robust conceptual model of the system. The resources model also provided some insight into clinicians' interactive strategies and patterns of associated errors. Implications for user training and interface design based on the principles of human-computer interaction in the medical domain are discussed.

Large area silicon sheet by EFG

NASA Technical Reports Server (NTRS)

1977-01-01

Some hypotheses to explain both of these features are advanced and the possible implications for solar cell performance are touched upon. The multiple ribbon growth system has shown a number of flaws with respect to the reliability of the basic furnace design. These definitely need to be rectified before any significant demonstration of multiple ribbon growth can proceed. The cartridges, however, have performed quite well. The work on 3" cartridge design and automatic controls has proceeded nearly on schedule and the report contains a detailed description of the approach and the equipment to be used for automatic control of ribbon growth.

Immunotherapy is different: Implications for vaccine clinical trial design.

PubMed

Simon, Richard

2017-09-02

Cancer Immunotherapetics differ fundamentally from most cancer therapies in that they involve manipulation of the immune system to induce an anti-tumor response. This fundamental difference results in differences in the pre-clinical and clinical development of immunotherapeutics. Even the regulatory culture of developing one drug at a time and demonstrating that it, when added to standard therapy, prolongs patient survival, is often not suitable for the development of effective immunotherapy regimens. In this commentary, we explore some of these differences and describe novel clinical trial designs which may be useful in immunotherapeutics regimen development.

Changing choices in health care: implications for equity, efficiency and cost.

PubMed

Bevan, Gwyn; Helderman, Jan-Kees; Wilsford, David

2010-07-01

Although choice may be seen as an end in itself, the papers included in this special issue of Health Economics, Policy and Law, examine choice policies in European systems of health care, which aim to be effective instruments for ameliorating the systemic pressures from the iron triangle of equity, efficiency, and cost. Three papers consider the nature of differences between and within countries following the Beveridge and Bismarck models of financing and organising the delivery of care, and how choices are changing within different systems. Within countries following the Beveridge model, current policies in England, Denmark and Sweden emphasise increasing patient choice of provider. Within countries following the Bismarck model, current policies in France and Germany seek to restrict choice of specialists by introducing 'soft' gatekeeping; and in the Netherlands there is a system of managed competition with choice of insurer that, in principle, allows insurers to contract selectively with providers. A fourth paper considers how government policies that seek to restrict choice within systems of universal coverage have been subject to challenges in the courts. A commentary explores the implications of the fraught and complex nature of choices between insurers and providers of health care for designing effective choice policies.

Designing and evaluating a STEM teacher learning opportunity in the research university.

PubMed

Hardré, Patricia L; Ling, Chen; Shehab, Randa L; Herron, Jason; Nanny, Mark A; Nollert, Matthias U; Refai, Hazem; Ramseyer, Christopher; Wollega, Ebisa D

2014-04-01

This study examines the design and evaluation strategies for a year-long teacher learning and development experience, including their effectiveness, efficiency and recommendations for strategic redesign. Design characteristics include programmatic features and outcomes: cognitive, affective and motivational processes; interpersonal and social development; and performance activities. Program participants were secondary math and science teachers, partnered with engineering faculty mentors, in a research university-based education and support program. Data from multiple sources demonstrated strengths and weaknesses in design of the program's learning environment, including: face-to-face and via digital tools; on-site and distance community interactions; and strategic evaluation tools and systems. Implications are considered for the strategic design and evaluation of similar grant-funded research experiences intended to support teacher learning, development and transfer. Copyright © 2013 Elsevier Ltd. All rights reserved.

Some Implications of Cognitive Theory for Instructional Design.

ERIC Educational Resources Information Center

Winn, William

1990-01-01

Examines some of the recent developments in cognitive theory and explores their implications for instructional design. Topics discussed include a shift from emphasis on behavioral theory to cognitive theory; task analysis; instructional objectives; learner characteristics; instructional strategies; metacognition; and the dynamic nature of…

Training wheelchair navigation in immersive virtual environments for patients with spinal cord injury - end-user input to design an effective system.

PubMed

Nunnerley, Joanne; Gupta, Swati; Snell, Deborah; King, Marcus

2017-05-01

A user-centred design was used to develop and test the feasibility of an immersive 3D virtual reality wheelchair training tool for people with spinal cord injury (SCI). A Wheelchair Training System was designed and modelled using the Oculus Rift headset and a Dynamic Control wheelchair joystick. The system was tested by clinicians and expert wheelchair users with SCI. Data from focus groups and individual interviews were analysed using a general inductive approach to thematic analysis. Four themes emerged: Realistic System, which described the advantages of a realistic virtual environment; a Wheelchair Training System, which described participants' thoughts on the wheelchair training applications; Overcoming Resistance to Technology, the obstacles to introducing technology within the clinical setting; and Working outside the Rehabilitation Bubble which described the protective hospital environment. The Oculus Rift Wheelchair Training System has the potential to provide a virtual rehabilitation setting which could allow wheelchair users to learn valuable community wheelchair use in a safe environment. Nausea appears to be a side effect of the system, which will need to be resolved before this can be a viable clinical tool. Implications for Rehabilitation Immersive virtual reality shows promising benefit for wheelchair training in a rehabilitation setting. Early engagement with consumers can improve product development.

Projection systems with a cut-off line for automotive applications

NASA Astrophysics Data System (ADS)

Kloos, G.; Eichhorn, K.

2005-08-01

The lighting systems of a car provide a variety of challenges from the point of view of illumination science and technology. Engineering work in this field has to deal both with reflector and lens design as well as with opto-mechanical design and sensor technology. It has direct implications on traffic safety and the efficiency in which energy is used. Therefore, these systems are continuously improved and optimized. In this context, adaptive systems that we investigate for automotive applications gain increasing importance. The properties of the light distribution in the vicinity of the cut-off line are of key importance for the safe and efficient operation of automotive headlamps. An alternative approach is proposed to refine the description of these properties in an attempt to make it more quantitative. This description is intended to facilitate intercomparison between different systems and/or to study environmental influences on the cut-off line of a system under investigation. Designing projection systems it is necessary to take a delicate trade-off between efficiency, light-distribution characteristics, mechanical boundary conditions, and legal requirements into account. Considerations and results on optical properties of three-axial reflectors in dependence of layout parameters will be given. They can serve as a guideline for the optical workshop and for free-form optimization.

GATEWAY Demonstrations: Tuning Hospital Lighting: Evaluating Tunable LED Lighting at the Swedish Hospital Behavioral Health Unit in Seattle

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wilkerson, Andrea; Davis, Robert G.; Clark, Edward

The GATEWAY program evaluated a tunable LED lighting system installed in the new Swedish Medical Behavioral Health Unit in Seattle that incorporates color-tunable luminaires in common areas, and uses advanced controls for dimming and color tuning, with the goal of providing a better environment for staff and patients. The report reviews the design of the tunable lighting system, summarizes two sets of measurements, and discusses the circadian, energy, and commissioning implications as well as lessons learned from the project.

GATEWAY Report Brief: Evaluating Tunable LED Lighting in the Swedish Medical Behavioral Health Unit

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

Summary of a GATEWAY report evaluation of a tunable LED lighting system installed in the new Swedish Medical Behavioral Health Unit in Seattle that incorporates color-tunable luminaires in common areas, and uses advanced controls for dimming and color tuning, with the goal of providing a better environment for staff and patients. The report reviews the design of the tunable lighting system, summarizes two sets of measurements, and discusses the circadian, energy, and commissioning implications as well as lessons learned from the project.

Integrated source and channel encoded digital communications system design study

NASA Technical Reports Server (NTRS)

Huth, G. K.

1974-01-01

Studies on the digital communication system for the direct communication links from ground to space shuttle and the links involving the Tracking and Data Relay Satellite (TDRS). Three main tasks were performed:(1) Channel encoding/decoding parameter optimization for forward and reverse TDRS links,(2)integration of command encoding/decoding and channel encoding/decoding; and (3) modulation coding interface study. The general communication environment is presented to provide the necessary background for the tasks and to provide an understanding of the implications of the results of the studies.

Feasibility and Design Implications of Fuel Cell Power for Sealift Ships

DTIC Science & Technology

2010-01-01

Feasibility and Design Implications of Fuel Cell Power for Sealift Ships Jing Suna, John Stebeb, and Colen Kennellb a Department of Naval...studies published so far have focused on ship service power or on propulsion power for small vessels with moderate power requirements. Using a ... a large military cargo ship. A notional solid oxide fuel cell (SOFC) module is proposed and the implications of the technology on fuel savings and

Physiological and biochemical response of plants to engineered NMs: Implications on future design.

PubMed

de la Rosa, Guadalupe; García-Castañeda, Concepción; Vázquez-Núñez, Edgar; Alonso-Castro, Ángel Josabad; Basurto-Islas, Gustavo; Mendoza, Ángeles; Cruz-Jiménez, Gustavo; Molina, Carlos

2017-01-01

Engineered nanomaterials (ENMs) form the basis of a great number of commodities that are used in several areas including energy, coatings, electronics, medicine, chemicals and catalysts, among others. In addition, these materials are being explored for agricultural purposes. For this reason, the amount of ENMs present as nanowaste has significantly increased in the last few years, and it is expected that ENMs levels in the environment will increase even more in the future. Because plants form the basis of the food chain, they may also function as a point-of-entry of ENMs for other living systems. Understanding the interactions of ENMs with the plant system and their role in their potential accumulation in the food chain will provide knowledge that may serve as a decision-making framework for the future design of ENMs. The purpose of this paper was to provide an overview of the current knowledge on the transport and uptake of selected ENMs, including Carbon Based Nanomaterials (CBNMs) in plants, and the implication on plant exposure in terms of the effects at the macro, micro, and molecular level. We also discuss the interaction of ENMs with soil microorganisms. With this information, we suggest some directions on future design and areas where research needs to be strengthened. We also discuss the need for finding models that can predict the behavior of ENMs based on their chemical and thermodynamic nature, in that few efforts have been made within this context. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

A performance improvement case study in aircraft maintenance and its implications for hazard identification.

PubMed

Ward, Marie; McDonald, Nick; Morrison, Rabea; Gaynor, Des; Nugent, Tony

2010-02-01

Aircraft maintenance is a highly regulated, safety critical, complex and competitive industry. There is a need to develop innovative solutions to address process efficiency without compromising safety and quality. This paper presents the case that in order to improve a highly complex system such as aircraft maintenance, it is necessary to develop a comprehensive and ecologically valid model of the operational system, which represents not just what is meant to happen, but what normally happens. This model then provides the backdrop against which to change or improve the system. A performance report, the Blocker Report, specific to aircraft maintenance and related to the model was developed gathering data on anything that 'blocks' task or check performance. A Blocker Resolution Process was designed to resolve blockers and improve the current check system. Significant results were obtained for the company in the first trial and implications for safety management systems and hazard identification are discussed. Statement of Relevance: Aircraft maintenance is a safety critical, complex, competitive industry with a need to develop innovative solutions to address process and safety efficiency. This research addresses this through the development of a comprehensive and ecologically valid model of the system linked with a performance reporting and resolution system.

Idiocultural Design as a Tool of Cultural Psychology.

PubMed

Cole, Michael

2017-09-01

The study of small group idiocultures offers a productive way to study the role of culture in human cognitive and social development. My evidence is drawn from a multi-decade long study of groups of mixed-aged participants engaged in deliberately designed forms of joint activity taking place several times a week over periods extending over decades in a variety of institutional settings. In each such system, participants ranging from middle childhood to adulthood participate in an after-school program composed of a wide variety of games brought together in a fantasy world watched over by a Wizard. Insights offered by this approach include comparative analysis of skill development in different idiocultural systems, intergenerational changes in the local cultural systems themselves, and intra-cultural variations in the behavioral changes of individual children occurring over different time scales. Implications of this comparative approach for psychology science are discussed.

Long Duration Exposure Facility (LDEF) optical systems SIG summary and database

NASA Astrophysics Data System (ADS)

Bohnhoff-Hlavacek, Gail

1992-09-01

The main objectives of the Long Duration Exposure Facility (LDEF) Optical Systems Special Investigative Group (SIG) Discipline are to develop a database of experimental findings on LDEF optical systems and elements hardware, and provide an optical system overview. Unlike the electrical and mechanical disciplines, the optics effort relies primarily on the testing of hardware at the various principal investigator's laboratories, since minimal testing of optical hardware was done at Boeing. This is because all space-exposed optics hardware are part of other individual experiments. At this time, all optical systems and elements testing by experiment investigator teams is not complete, and in some cases has hardly begun. Most experiment results to date, document observations and measurements that 'show what happened'. Still to come from many principal investigators is a critical analysis to explain 'why it happened' and future design implications. The original optical system related concerns and the lessons learned at a preliminary stage in the Optical Systems Investigations are summarized. The design of the Optical Experiments Database and how to acquire and use the database to review the LDEF results are described.

Long Duration Exposure Facility (LDEF) optical systems SIG summary and database

NASA Technical Reports Server (NTRS)

Bohnhoff-Hlavacek, Gail

1992-01-01

The main objectives of the Long Duration Exposure Facility (LDEF) Optical Systems Special Investigative Group (SIG) Discipline are to develop a database of experimental findings on LDEF optical systems and elements hardware, and provide an optical system overview. Unlike the electrical and mechanical disciplines, the optics effort relies primarily on the testing of hardware at the various principal investigator's laboratories, since minimal testing of optical hardware was done at Boeing. This is because all space-exposed optics hardware are part of other individual experiments. At this time, all optical systems and elements testing by experiment investigator teams is not complete, and in some cases has hardly begun. Most experiment results to date, document observations and measurements that 'show what happened'. Still to come from many principal investigators is a critical analysis to explain 'why it happened' and future design implications. The original optical system related concerns and the lessons learned at a preliminary stage in the Optical Systems Investigations are summarized. The design of the Optical Experiments Database and how to acquire and use the database to review the LDEF results are described.

Survey of Media Forms and Information Flow Models in Microsystems Companies

NASA Astrophysics Data System (ADS)

Durugbo, Christopher; Tiwari, Ashutosh; Alcock, Jeffery R.

The paper presents the findings of a survey of 40 microsystems companies that was carried out to determine the use and the purpose of use of media forms and information flow models within these companies. These companies as 'product-service systems' delivered integrated products and services to realise customer solutions. Data collection was carried out by means of an online survey over 3 months. The survey revealed that 42.5% of respondents made use of data flow diagrams and 10% made use of design structure matrices. The survey also suggests that a majority of companies (75%) made use of textual and diagrammatic media forms for communication, analysis, documentation and representation during design and development processes. The paper also discusses the implications of the survey findings to product-service systems.

Distributions of underdense meteor trail amplitudes and its application to meteor scatter communication system design

NASA Astrophysics Data System (ADS)

Weitzen, J. A.; Bourque, S.; Ostergaard, J. C.; Bench, P. M.; Baily, A. D.

1991-04-01

Analysis of data from recent experiments leads to the observation that distributions of underdense meteor trail peak signal amplitudes differ from classic predictions. In this paper the distribution of trail amplitudes in decibels relative 1 W (dBw) is considered, and it is shown that Lindberg's theorem can be used to apply central limit arguments to this problem. It is illustrated that a Gaussian model for the distribution of the logarithm of the peak received signal level of underdense trails provides a better fit to data than classic approaches. Distributions of underdense meteor trail amplitudes at five frequencies are compared to a Gaussian distribution and the classic model. Implications of the Gaussian assumption on the design of communication systems are discussed.

In vitro anticancer effects of a RAGE inhibitor discovered using a structure-based drug design system

PubMed Central

El-Far, Ali Hafez Ali Mohammed; Munesue, Seiichi; Harashima, Ai; Sato, Akira; Shindo, Mika; Nakajima, Shingo; Inada, Mana; Tanaka, Mariko; Takeuchi, Akihiko; Tsuchiya, Hiroyuki; Yamamoto, Hiroshi; Shaheen, Hazem M.E.; El-Sayed, Yasser S.; Kawano, Shuhei; Tanuma, Sei-Ichi; Yamamoto, Yasuhiko

2018-01-01

Receptor for advanced glycation end-products (RAGE) is a pattern recognition receptor implicated in the pathogenesis of certain types of cancer. In the present study, papaverine was identified as a RAGE inhibitor using the conversion to small molecules through optimized-peptide strategy drug design system. Papaverine significantly inhibited RAGE-dependent nuclear factor κ-B activation driven by high mobility group box-1, a RAGE ligand. Using RAGE- or dominant-negative RAGE-expressing HT1080 human fibrosarcoma cells, the present study revealed that papaverine suppressed RAGE-dependent cell proliferation and migration dose-dependently. Furthermore, papaverine significantly inhibited cell invasion. The results of the present study suggested that papaverine could inhibit RAGE, and provided novel insights into the field of RAGE biology, particularly anticancer therapies. PMID:29541234

Thermographic Sensing For On-Line Industrial Control

NASA Astrophysics Data System (ADS)

Holmsten, Dag

1986-10-01

It is today's emergence of thermoelectrically cooled, highly accurate infrared linescanners and imaging systems that has definitely made on-line Infraread Thermography (IRT) possible. Specifically designed for continuous use, these scanners are equipped with dedicated software capable of monitoring and controlling highly complex thermodynamic situations. This paper will outline some possible implications of using IRT on-line by describing some uses of this technology in the steel-making (hot rolling) and automotive industries (machine-vision). A warning is also expressed that IRT technology not originally designed for automated applications e.g. high resolution, imaging systems, should not be directly applied to an on-line measurement situation without having its measurement resolution, accuracy and especially its repeatability, reliably proven. Some suitable testing procedures are briefly outlined at the end of the paper.

From Fatigue to Anxiety? Implications for Educational Design in a Web 2.0 World

ERIC Educational Resources Information Center

Mathew, David

2012-01-01

Purpose: The purpose of the paper is to recognise that as educators moving into, or already in, a Web 2.0 world, we are likely to experience anxiety, and to explore the implications for educational design in a Web 2.0 world. Design/methodology/approach: The objectives are achieved as the result of recent successes with the commissioners for two…

Instructional Plans and Situated Learning: The Challenge of Suchman's Theory of Situated Action for Instructional Designers and Instructional Systems.

ERIC Educational Resources Information Center

Streibel, Michael J.

This paper discusses the implications of Lucy Suchman's conclusion that a theory of situated action--i.e., the actual sense that specific users make out of specific Xeroxing events--is truer to the lived experience of Xerox users than a cognitive account of the user's plans--e.g., the hierarchy of subprocedures for how Xerox machines should be…

Examining the Effects of Field Dependence-Independence on Learners' Problem-Solving Performance and Interaction with a Computer Modeling Tool: Implications for the Design of Joint Cognitive Systems

ERIC Educational Resources Information Center

Angeli, Charoula

2013-01-01

An investigation was carried out to examine the effects of cognitive style on learners' performance and interaction during complex problem solving with a computer modeling tool. One hundred and nineteen undergraduates volunteered to participate in the study. Participants were first administered a test, and based on their test scores they were…

Global Networks: Emerging Constraints on Strategy (Defense Horizons, July 2004)

DTIC Science & Technology

2004-07-01

that will have a substantial and long-term economic impact , as well as political, social , and security implications.28 This is not just about selling...fundamentally, the economic, social , and political relationships premised on them change as well. Historical forces drive the system to a new...telecommunications network design. These are not sweatshops . Working conditions at India’s IT develop- ment companies—whether managed directly by Western

Analysis of U. S. Forest Service bird point-count monitoring database - implications for designing and implementing avian monitoring

Treesearch

Eric T. Linder; David A. Buehler

2005-01-01

In 1996, Region 8 of the U. S. Forest Service implemented a program to monitor landbirds on southeastern U.S. national forests. The goal was to develop a monitoring system that could document population trends and bird-habitat relationships. Using power analysis, we examined the ability of the monitoring program to detect population trends (3 percent annual change) at...

Listener Habits and Choices — and Their Implications for Public Performance Venues

NASA Astrophysics Data System (ADS)

DODD, G.

2001-01-01

An 11-year longitudinal survey of patterns and preferences in music listening has revealed that a large majority of people would prefer to listen to music performed live but that only a small percentage of their exposure to music actually occurs at live performances. An initial analysis of the first few years of the survey suggests that choices concerning music can be influenced by cultural background, and that predominant music sources change as new technology becomes available. Reasons given by listeners for preferring to listen to a traditional, mechanical instrument rather than an electro-acoustic version of it indicate they are sensitive to an “originality” criterion. As a consequence, concert halls should be designed to operate as passive acoustics spaces. Further, listeners' reasons for electing to attend a live performance rather than listen to a recording or a live broadcast suggest that hall designers should try to maximize the sense of two-way communication between performers and listeners. An implication of this is that where active acoustics systems are to be incorporated in variable acoustics auditoria, those active systems which use a non-in-line approach are to be preferred over in-line schemes. However, listener evolution and new expectations may require a fundamental change in our approach to the acoustics of live performance venues.

The relationship between vitamin D and the renin-angiotensin system in the pathophysiology of hypertension, kidney disease, and diabetes.

PubMed

Vaidya, Anand; Williams, Jonathan S

2012-04-01

Vitamin D has been implicated in the pathophysiology of extraskeletal conditions such as hypertension, kidney disease, and diabetes via its ability to negatively regulate the renin-angiotensin system (RAS). This article reviews the evidence supporting a link between vitamin D and the RAS in these conditions, with specific emphasis on translational observations and their limitations. A literature review of animal and human studies evaluating the role of vitamin D in hypertension, kidney disease, and diabetes was performed. Excess activity of the RAS has been implicated in the pathogenesis of hypertension, chronic kidney disease, decreased insulin secretion, and insulin resistance. Animal studies provide strong support for 1,25-dihydroxyvitamin D(3)-mediated downregulation of renin expression and RAS activity via its interaction with the vitamin D receptor. Furthermore, the activity of vitamin D metabolites in animals is associated with reductions in blood pressure, proteinuria and renal injury, and with improved β-cell function. Many observational, and a few interventional, studies in humans have supported these findings; however, there is a lack of well-designed prospective human interventional studies to definitively assess clinical outcomes. There is a need for more well-designed prospective interventional studies to validate this hypothesis in human clinical outcomes. Copyright © 2012 Elsevier Inc. All rights reserved.

Examining the Use of a Visual Analytics System for Sensemaking Tasks: Case Studies with Domain Experts.

PubMed

Kang, Youn-Ah; Stasko, J

2012-12-01

While the formal evaluation of systems in visual analytics is still relatively uncommon, particularly rare are case studies of prolonged system use by domain analysts working with their own data. Conducting case studies can be challenging, but it can be a particularly effective way to examine whether visual analytics systems are truly helping expert users to accomplish their goals. We studied the use of a visual analytics system for sensemaking tasks on documents by six analysts from a variety of domains. We describe their application of the system along with the benefits, issues, and problems that we uncovered. Findings from the studies identify features that visual analytics systems should emphasize as well as missing capabilities that should be addressed. These findings inform design implications for future systems.

Implications of Privacy Needs and Interpersonal Distancing Mechanisms for Space Station Design

NASA Technical Reports Server (NTRS)

Harrison, A. A.; Sommer, R.; Struthers, N.; Hoyt, K.

1986-01-01

The literature on privacy needs, personal space, interpersonal distancing, and crowding is reveiwed with special reference to spaceflight and spaceflight analogous conditions. A quantitative model is proposed for understanding privacy, interpersonal distancing, and performance. The implications for space station design is described.

Using Visualization in Cockpit Decision Support Systems

NASA Technical Reports Server (NTRS)

Aragon, Cecilia R.

2005-01-01

In order to safely operate their aircraft, pilots must make rapid decisions based on integrating and processing large amounts of heterogeneous information. Visual displays are often the most efficient method of presenting safety-critical data to pilots in real time. However, care must be taken to ensure the pilot is provided with the appropriate amount of information to make effective decisions and not become cognitively overloaded. The results of two usability studies of a prototype airflow hazard visualization cockpit decision support system are summarized. The studies demonstrate that such a system significantly improves the performance of helicopter pilots landing under turbulent conditions. Based on these results, design principles and implications for cockpit decision support systems using visualization are presented.

Sociotechnical systems as a framework for regulatory system design and evaluation: Using Work Domain Analysis to examine a new regulatory system.

PubMed

Carden, Tony; Goode, Natassia; Read, Gemma J M; Salmon, Paul M

2017-03-15

Like most work systems, the domain of adventure activities has seen a series of serious incidents and subsequent calls to improve regulation. Safety regulation systems aim to promote safety and reduce accidents. However, there is scant evidence they have led to improved safety outcomes. In fact there is some evidence that the poor integration of regulatory system components has led to adverse safety outcomes in some contexts. Despite this, there is an absence of methods for evaluating regulatory and compliance systems. This article argues that sociotechnical systems theory and methods provide a suitable framework for evaluating regulatory systems. This is demonstrated through an analysis of a recently introduced set of adventure activity regulations. Work Domain Analysis (WDA) was used to describe the regulatory system in terms of its functional purposes, values and priority measures, purpose-related functions, object-related processes and cognitive objects. This allowed judgement to be made on the nature of the new regulatory system and on the constraints that may impact its efficacy following implementation. Importantly, the analysis suggests that the new system's functional purpose of ensuring safe activities is not fully supported in terms of the functions and objects available to fulfil them. Potential improvements to the design of the system are discussed along with the implications for regulatory system design and evaluation across the safety critical domains generally. Copyright © 2017 Elsevier Ltd. All rights reserved.

International Conference on Hypersonic Flight in the 21st Century, 1st, University of North Dakota, Grand Forks, Sept. 20-23, 1988, Proceedings

NASA Astrophysics Data System (ADS)

Higbea, Mary E.; Vedda, James A.

The present conference on the development status of configurational concepts and component technologies for hypersonic-cruise and transatmospheric vehicles discusses topics relating to the U.S. National Aerospace Plane program, ESA-planned aerospace vehicles, Japanese spaceplane concepts, the integration of hypersonic aircraft into existing infrastructures, hypersonic airframe designs, hypersonic avionics and cockpit AI systems, hypersonic-regime CFD techniques, the economics of hypersonic vehicles, and possible legal implications of hypersonic flight. Also discussed are Soviet spaceplane concepts, propulsion systems involving laser power sources and hypervelocity launch technologies, and the management of support systems operations for hypersonic vehicles.

Simulation and Modeling of Positrons and Electrons in advanced Time-of-Flight Positron Annihilation Induced Auger Electron Spectroscopy Systems

NASA Astrophysics Data System (ADS)

Joglekar, Prasad; Shastry, Karthik; Satyal, Suman; Weiss, Alexander

2011-10-01

Time of Flight Positron Annihilation Induced Auger Electron Spectroscopy (T-O-F PAES) is a highly surface selective analytical technique in which elemental identification is accomplished through a measurement of the flight time distributions of Auger electrons resulting from the annihilation of core electron by positrons. SIMION charged particle optics simulation software was used to model the trajectories both the incident positrons and outgoing electrons in our existing T-O-F PAES system as well as in a new system currently under construction in our laboratory. The implication of these simulation regarding the instrument design and performance are discussed.

An augmented reality (AR)-based vocational task prompting system for people with cognitive impairments.

PubMed

Chang, Yao-Jen; Kang, Ya-Shu; Huang, Po-Chiao

2013-10-01

This study assessed the possibility of training three people with cognitive impairments using an augmented reality (AR)-based task prompting system. Using AR technology, the system provided picture cues, identified incorrect task steps on the fly, and helped users make corrections. Based on a multiple baseline design, the data showed that the three participants considerably increased their target response, which improved their vocational job skills during the intervention phases and enabled them to maintain the acquired job skills after intervention. The practical and developmental implications of the results are discussed. Copyright © 2013 Elsevier Ltd. All rights reserved.

Characterization of 3D interconnected microstructural network in mixed ionic and electronic conducting ceramic composites

NASA Astrophysics Data System (ADS)

Harris, William M.; Brinkman, Kyle S.; Lin, Ye; Su, Dong; Cocco, Alex P.; Nakajo, Arata; Degostin, Matthew B.; Chen-Wiegart, Yu-Chen Karen; Wang, Jun; Chen, Fanglin; Chu, Yong S.; Chiu, Wilson K. S.

2014-04-01

The microstructure and connectivity of the ionic and electronic conductive phases in composite ceramic membranes are directly related to device performance. Transmission electron microscopy (TEM) including chemical mapping combined with X-ray nanotomography (XNT) have been used to characterize the composition and 3-D microstructure of a MIEC composite model system consisting of a Ce0.8Gd0.2O2 (GDC) oxygen ion conductive phase and a CoFe2O4 (CFO) electronic conductive phase. The microstructural data is discussed, including the composition and distribution of an emergent phase which takes the form of isolated and distinct regions. Performance implications are considered with regards to the design of new material systems which evolve under non-equilibrium operating conditions.The microstructure and connectivity of the ionic and electronic conductive phases in composite ceramic membranes are directly related to device performance. Transmission electron microscopy (TEM) including chemical mapping combined with X-ray nanotomography (XNT) have been used to characterize the composition and 3-D microstructure of a MIEC composite model system consisting of a Ce0.8Gd0.2O2 (GDC) oxygen ion conductive phase and a CoFe2O4 (CFO) electronic conductive phase. The microstructural data is discussed, including the composition and distribution of an emergent phase which takes the form of isolated and distinct regions. Performance implications are considered with regards to the design of new material systems which evolve under non-equilibrium operating conditions. Electronic supplementary information (ESI) available. See DOI: 10.1039/c3nr06684c

Discrete dynamical system modelling for gene regulatory networks of 5-hydroxymethylfurfural tolerance for ethanologenic yeast.

PubMed

Song, M; Ouyang, Z; Liu, Z L

2009-05-01

Composed of linear difference equations, a discrete dynamical system (DDS) model was designed to reconstruct transcriptional regulations in gene regulatory networks (GRNs) for ethanologenic yeast Saccharomyces cerevisiae in response to 5-hydroxymethylfurfural (HMF), a bioethanol conversion inhibitor. The modelling aims at identification of a system of linear difference equations to represent temporal interactions among significantly expressed genes. Power stability is imposed on a system model under the normal condition in the absence of the inhibitor. Non-uniform sampling, typical in a time-course experimental design, is addressed by a log-time domain interpolation. A statistically significant DDS model of the yeast GRN derived from time-course gene expression measurements by exposure to HMF, revealed several verified transcriptional regulation events. These events implicate Yap1 and Pdr3, transcription factors consistently known for their regulatory roles by other studies or postulated by independent sequence motif analysis, suggesting their involvement in yeast tolerance and detoxification of the inhibitor.

SynchroPhasor Measurements: System Architecture and Performance Evaluation in Supporting Wide-Area Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, Zhenyu; Dagle, Jeffery E.

2008-07-31

The infrastructure of phasor measurements have evolved over the last two decades from isolated measurement units to networked measurement systems with footprints beyond individual utility companies. This is, to a great extent, a bottom-up self-evolving process except some local systems built by design. Given the number of phasor measurement units (PMUs) in the system is small (currently 70 each in western and eastern interconnections), current phasor network architecture works just fine. However, the architecture will become a bottleneck when large number of PMUs are installed (e.g. >1000~10000). The need for phasor architecture design has yet to be addressed. This papermore » reviews the current phasor networks and investigates future architectures, as related to the efforts undertaken by the North America SynchroPhasor Initiative (NASPI). Then it continues to present staged system tests to evaluate the performance of phasor networks, which is a common practice in the Western Electricity Coordinating Council (WECC) system. This is followed by field measurement evaluation and the implication of phasor quality issues on phasor applications.« less

Cybernetic systems based on inductive logic

NASA Astrophysics Data System (ADS)

Fry, Robert L.

2001-05-01

Recent work in the area of inductive logic suggests that cybernetics might be quantified and reduced to engineering practice. If so, then there are considerable implications for engineering, science, and other fields. This paper attempts to capture the essential ideas of cybernetics cast in the light of inductive logic. The described inductive logic extends conventional logic by adding a conjugate logical domain of questions to the logical domain of assertions intrinsic to Boolean Algebra with which most are familiar. This was first posited and developed by Richard Cox. Interestingly enough, these two logical domains, one of questions and the other of assertions, only exist relative to one another with each possessing natural measures of entropy and probability, respectively. Examples are given that highlight the utility of cybernetic approaches to neuroscience, algorithm design, system engineering, and the design and understanding of defensive and offensive systems. For example, the application of cybernetic approaches to defense systems suggests that these systems possess a wavefunction which like quantum mechanics, collapses when we ``look'' through the eyes of the system sensors such as radars and optical sensors. .

Section 3: Quality and Value-Based Requirements

NASA Astrophysics Data System (ADS)

Mylopoulos, John

Traditionally, research and practice in software engineering has focused its attention on specific software qualities, such as functionality and performance. According to this perspective, a system is deemed to be of good quality if it delivers all required functionality (“fitness-for-purpose”) and its performance is above required thresholds. Increasingly, primarily in research but also in practice, other qualities are attracting attention. To facilitate evolution, maintainability and adaptability are gaining popularity. Usability, universal accessibility, innovativeness, and enjoyability are being studied as novel types of non-functional requirements that we do not know how to define, let alone accommodate, but which we realize are critical under some contingencies. The growing importance of the business context in the design of software-intensive systems has also thrust economic value, legal compliance, and potential social and ethical implications into the forefront of requirements topics. A focus on the broader user environment and experience, as well as the organizational and societal implications of system use, thus has become more central to the requirements discourse. This section includes three contributions to this broad and increasingly important topic.

Biosimilar Products in the Modern U.S. Health Care and Regulatory Landscape.

PubMed

Peterson, Jesse; Budlong, Holly; Affeldt, Tim; Skiermont, Kyle; Kyllo, Gregg; Heaton, Al

2017-12-01

Biosimilars have the potential to greatly reduce medication costs in the United States. As of July 1, 2017, 5 biosimilars have been approved by the FDA, but only 2 are available for purchase. This commentary outlines the efforts of an integrated health system to ensure biosimilar accessibility and discusses the current challenges and future implications. We highlight the implementation of a health plan policy and how a health system's formulary committee can encourage use while considering provider perceptions and operational challenges. In addition, we provide our perspective on potential implications for pricing, site of care, and pharmacy dispensing practices based on our experience with regulatory hurdles and market trends. Overall, we believe biosimilars are a good thing for the health care system, but their expected benefit may not be realized for years to come. No outside funding supported this work. Affeldt reports advisory board membership with Janssen, and Skiermont reports membership with Amgen and McKesson. The other authors have nothing to disclose. Peterson and Budlong contributed the study concept and design and wrote the manuscript. Affeldt, Skiermont, Kyllo, and Heaton reviewed and revised the manuscript.

Improvement attributes in healthcare: implications for integrated care.

PubMed

Harnett, Patrick John

2018-04-16

Purpose Healthcare quality improvement is a key concern for policy makers, regulators, carers and service users. Despite a contemporary consensus among policy makers that integrated care represents a means to substantially improve service outcomes, progress has been slow. Difficulties achieving sustained improvement at scale imply that methods employed are not sufficient and that healthcare improvement attributes may be different when compared to prior reference domains. The purpose of this paper is to examine and synthesise key improvement attributes relevant to a complex healthcare change process, specifically integrated care. Design/methodology/approach This study is based on an integrative literature review on systemic improvement in healthcare. Findings A central theme emerging from the literature review indicates that implementing systemic change needs to address the relationship between vision, methods and participant social dynamics. Practical implications Accommodating personal and professional network dynamics is required for systemic improvement, especially among high autonomy individuals. This reinforces the need to recognise the change process as taking place in a complex adaptive system where personal/professional purpose/meaning is central to the process. Originality/value Shared personal/professional narratives are insufficiently recognised as a powerful change force, under-represented in linear and rational empirical improvement approaches.

About the Effect of Control on Flutter and Post-Flutter of a Supersonic/Hypersonic Cross-Sectional Wing

NASA Technical Reports Server (NTRS)

Silva, Walter A.; Librescu, Liviu; Marzocca, Piergiovanni

2001-01-01

The control of the flutter instability and the conversion of the dangerous character of the flutter instability boundary into the undangerous one of a cross-sectional wing in a supersonic/hypersonic flow field is presented. The objective of this paper is twofold: i) to analyze the implications of nonlinear unsteady aerodynamics and physical nonlinearities on the character of the instability boundary in the presence of a control capability, and ii) to outline the effects played in the same respect by some important parameters of the aeroelastic system. As a by-product of this analysis, the implications of the active control on the linearized flutter behavior of the system are captured and emphasized. The bifurcation behavior of the open/closed loop aeroelastic system in the vicinity of the flutter boundary is studied via the use of a new methodology based on the Liapunov First Quantity. The expected outcome of this study is: a) to greatly enhance the scope and reliability of the aeroelastic analysis and design criteria of advanced supersonic/hypersonic flight vehicles and, b) provide a theoretical basis for the analysis of more complex nonlinear aeroelastic systems.

About the Effect of Control on Flutter and Post-Flutter of a Supersonic/Hypersonic Cross-Sectional Wing

NASA Technical Reports Server (NTRS)

Marzocca, Piergiovanni; Librescu, Liviu; Silva, Walter A.

2000-01-01

The control of the flutter instability and the conversion of the dangerous character of the flutter instability boundary into the undangerous one of a cross-sectional wing in a supersonic/hypersonic flow field is presented. The objective of this paper is twofold: i) to analyze the implications of nonlinear unsteady aerodynamics and physical nonlinearities on the character of the instability boundary in the presence of a control capability, and ii) to outline the effects played in the same respect by some important parameters of the aeroelastic system. As a by-product of this analysis, the implications of the active control on the linearized flutter behavior of the system are captured and emphasized. The bifurcation behavior of the open/closed loop aeroelastic system in the vicinity of the flutter boundary is studied via the use of a new methodology based on the Liapunov First Quantity. The expected outcome of this study is: a) to greatly enhance the scope and reliability of the aeroelastic analysis and design criteria of advanced supersonic/hypersonic flight vehicles and, b) provide a theoretical basis for the analysis of more complex nonlinear aeroelastic systems.

Design engineer perceptions and attitudes regarding human factors application to nuclear power plant design

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ma, R.; Jones, J. M.

2006-07-01

With the renewed interest in nuclear power and the possibility of constructing new reactors within the next decade in the U.S., there are several challenges for the regulators, designers, and vendors. One challenge is to ensure that Human Factors Engineering (HFE) is involved, and correctly applied in the life-cycle design of the Nuclear Power Plant (NPP). As an important part of the effort, people would ask: 'is the system-design engineer effectively incorporating HFE in the NPPs design?' The present study examines the sagacity of Instrumentation and Control design engineers on issues relating to awareness, attitude, and application of HFE inmore » NPP design. A questionnaire was developed and distributed, focusing on the perceptions and attitudes of the design engineers. The responses revealed that, while the participants had a relatively high positive attitude about HFE, their awareness and application of HFE were moderate. The results also showed that senior engineers applied HFE more frequently in their design work than young engineers. This study provides some preliminary results and implications for improved HFE education and application in NPP design. (authors)« less

Green Secure Processors: Towards Power-Efficient Secure Processor Design

NASA Astrophysics Data System (ADS)

Chhabra, Siddhartha; Solihin, Yan

With the increasing wealth of digital information stored on computer systems today, security issues have become increasingly important. In addition to attacks targeting the software stack of a system, hardware attacks have become equally likely. Researchers have proposed Secure Processor Architectures which utilize hardware mechanisms for memory encryption and integrity verification to protect the confidentiality and integrity of data and computation, even from sophisticated hardware attacks. While there have been many works addressing performance and other system level issues in secure processor design, power issues have largely been ignored. In this paper, we first analyze the sources of power (energy) increase in different secure processor architectures. We then present a power analysis of various secure processor architectures in terms of their increase in power consumption over a base system with no protection and then provide recommendations for designs that offer the best balance between performance and power without compromising security. We extend our study to the embedded domain as well. We also outline the design of a novel hybrid cryptographic engine that can be used to minimize the power consumption for a secure processor. We believe that if secure processors are to be adopted in future systems (general purpose or embedded), it is critically important that power issues are considered in addition to performance and other system level issues. To the best of our knowledge, this is the first work to examine the power implications of providing hardware mechanisms for security.

Information technology from novice to expert: implementation implications.

PubMed

Courtney, Karen L; Alexander, Gregory L; Demiris, George

2008-09-01

This paper explores how the Novice-to-Expert Nursing Practice framework can illuminate the challenges of and opportunities in implementing information technology (IT), such as clinical decision support systems (CDSS), in nursing practice. IT implementation in health care is increasing; however, substantial costs and risks remain associated with these projects. The theoretical framework of Novice-to-Expert Nursing Practice was applied to current design and implementation literature for CDSS. Organizational policies and CDSS design affect implementation and user adoption. Nursing CDSS can improve the overall quality of care when designed for the appropriate end-user group and based on a knowledge base reflecting nursing expertise. Nurse administrators can positively influence CDSS function and end-user acceptance by participating in and facilitating staff nurse involvement in IT design, planning and implementation. Specific steps for nurse administrators and managers are included in this paper.

Benefit design innovations: implications for consumer-directed health care.

PubMed

Tu, Ha T; Ginsburg, Paul B

2007-02-01

Current health insurance benefit designs that simply rely on higher, one-size-fits-all patient cost sharing have limited potential to curb rapidly rising costs, but innovations in benefit design can potentially make cost sharing a more effective tool, according to a new study by the Center for Studying Health System Change (HSC). Innovative benefit designs include incentives to encourage healthy behaviors; incentives that vary by service type, patient condition or enrollee income; and incentives to use efficient providers. But most applications of these innovative designs are not widespread, suggesting that any significant cost impact is many years off. Moreover, regulations governing high-deductible, consumer-directed health plans eligible for health savings accounts (HSAs) preclude some promising benefit design innovations and dilute the incentives in others. A movement away from a one-size-fits-all HSA benefit structure toward a more flexible design might broaden the appeal of HSA plans and enable them to incorporate features that promote cost-effective care.

Multiscale design and life-cycle based sustainability assessment of polymer nanocomposite coatings

NASA Astrophysics Data System (ADS)

Uttarwar, Rohan G.

In recent years, nanocoatings with exceptionally improved and new performance properties have found numerous applications in the automotive, aerospace, ship-making, chemical, electronics, steel, construction, and many other industries. Especially the formulations providing multiple functionalities to cured paint films are believed to dominate the coatings market in the near future. It has shifted the focus of research towards building sustainable coating recipes which can deliver multiple functionalities through applied films. The challenge to this exciting area of research arrives from the insufficient knowledge about structure-property correlations of nanocoating materials and their design complexity. Experimental efforts have been successful in developing certain types of nanopaints exhibiting improved properties. However, multifunctional nanopaint design optimality is extremely difficult to address if not impossible solely through experiments. In addition to this, the environmental implications and societal risks associated with this growing field of nanotechnology raise several questions related to its sustainable development. This research focuses on the study of a multiscale sustainable nanocoating design which can have the application from novel function envisioning and idea refinement point of view, to knowledge discovery and design solution derivation, and further to performance testing in industrial applications. The nanocoating design is studied using computational simulations of nano- to macro- scale models and sustainability assessment study over the life-cycle. Computational simulations aim at integrating top-down, goals/means, inductive systems engineering and bottom-up, cause and effect, deductive systems engineering approaches for material development. The in-silico paint resin system is a water-dispersible acrylic polymer with hydrophilic nanoparticles incorporated into it. The nano-scale atomistic and micro-scale coarse-grained (CG) level simulations are performed using molecular dynamics methodology to study several structural and morphological features such as effect of polymer molecular weight, polydispersity, rheology, nanoparticle volume fraction, size, shape and chemical nature on the bulk mechanical and self-cleaning properties of the coating film. At macro-scale, a paint spray system which is used for automotive coating application is studied by using CFD-based simulation methodology to generate crucial information about the effects of nanocoating technology on environmental emissions and coating film quality. The cradle-to-grave life-cycle based sustainability assessment study address all the critical issues related to economic benefits, environmental implications and societal effects of nanocoating technology through case studies of automotive coating systems. It is accomplished by identifying crucial correlations among measurable parameters at different stages and developing sustainability indicator matrices for analysis of each stage of life-cycle. The findings from the research can have great potential to draft useful conclusions in favor of future development of coating systems with novel functionalities and improved sustainability.

Virtual Acoustics, Aeronautics and Communications

NASA Technical Reports Server (NTRS)

Begault, Durand R.; Null, Cynthia H. (Technical Monitor)

1996-01-01

An optimal approach to auditory display design for commercial aircraft would utilize both spatialized ("3-D") audio techniques and active noise cancellation for safer operations. Results from several aircraft simulator studies conducted at NASA Ames Research Center are reviewed, including Traffic alert and Collision Avoidance System (TCAS) warnings, spoken orientation "beacons" for gate identification and collision avoidance on the ground, and hardware for improved speech intelligibility. The implications of hearing loss amongst pilots is also considered.

The Implications of Using Integrated Software Support Environment for Design of Guidance and Control Systems Software

DTIC Science & Technology

1990-02-01

inspections are performed before each formal review of each software life cycle phase. * Required software audits are performed . " The software is acceptable... Audits : Software audits are performed bySQA consistent with thegeneral audit rules and an auditreportis prepared. Software Quality Inspection (SQI...DSD Software Development Method 3-34 DEFINITION OF ACRONYMS Acronym Full Name or Description MACH Methode d’Analyse et de Conception Flierarchisee

Virtual acoustics, aeronautics, and communications

NASA Technical Reports Server (NTRS)

Begault, D. R.; Wenzel, E. M. (Principal Investigator)

1998-01-01

An optimal approach to auditory display design for commercial aircraft would utilize both spatialized (3-D) audio techniques and active noise cancellation for safer operations. Results from several aircraft simulator studies conducted at NASA Ames Research Center are reviewed, including Traffic alert and Collision Avoidance System (TCAS) warnings, spoken orientation "beacons" for gate identification and collision avoidance on the ground, and hardware for improved speech intelligibility. The implications of hearing loss among pilots is also considered.

Mechanical Adaptivity as a Process: Implications to New Materials and Material System Design

DTIC Science & Technology

2012-08-01

Deliver. Rev. 2004 Microactuators and valves Uses: • Drug delivery • Microfluidic actuators, valves , and pumps • Chemical and biological Sensors... paper where they did a study with f the stoichiometric parameter involved in the reduction step, and they looked at 2 X* - both far away from the...through strain? How do varying material properties affect behavior? Smith, Vaia et al. submitted 2012 23 Fibrous Paper Next Step: Heterogeneous

Weapon System Implications of RLPG Technology

DTIC Science & Technology

2000-01-01

the extreme emphasis placed on minimizing volume under armor . For an RLPG, the space required is further reduced because, unlike the case with an SPG...ensuring that all the on-board missiles can be launched from under armor . Currently, vehicle-launched missiles are fired from racks of four launch...reload is not done under armor . External, manual reload for the direct-fire role is simply not feasible operationally. It is possible to design a

RADC (Rome Air Development Center) System/Software Requirements Engineering Testbed Research and Development Program

DTIC Science & Technology

1988-06-01

analyze requirements to investigate assumptions, decisions , irplications, and requirements quality: (1) expected cost and risk of developing the...the requirements Including the rationale and Implications of decisions that were made. Tool Integration and Evaluation In the Integration and...ly. Instead of stating his needs and making decisions at the mission level, the user is forced to work at a design level or use the English language

A Quantitative and Qualitative Review of the Implementation of a Healthcare Information Network.

DTIC Science & Technology

1997-04-01

Kekre , Sunder , Mayuram S. Krishnan. "Drivers of Customer Satisfaction for Software Products: Implications for Design and Service Support." Management...1995. Huth, E.J. "Needed: An Economic Approach to Systems for Medical Information." Ann Internal Med. 103, no. 4 (1985): 617-19. Kekre , Sunder ... Kekre et. al. discuss similar issues 32 as Goodhue and Austin, but they use slightly different terminology. Kekre’s team determined that

Misclassification of childhood homicide on death certificates.

PubMed Central

Lapidus, G D; Gregorio, D I; Hansen, H

1990-01-01

Suspect classification of homicide deaths of Connecticut residents under 20 years of age was noted for 29 percent of cases examined. Misclassification was attributed to incomplete or erroneous information recorded on the death certificates, rather than errors in the designation of ICD-9 homicide codes. The results have important implications in the interpretation of vital statistics when homicide is listed as the cause of death and underscore the value of record linkage systems. PMID:2297072

Spacecraft external molecular contamination analysis

NASA Technical Reports Server (NTRS)

Ehlers, H. K. F.

1990-01-01

Control of contamination on and around spacecraft is required to avoid adverse effects on the performance of instruments and spacecraft systems. Recent work in this area is reviewed and discussed. Specific issues and limitations to be considered as part of the effort to predict contamination effects using modeling techniques are addressed. Significant results of Space Shuttle missions in the field of molecule/surface interactions as well as their implications for space station design and operation are reviewed.

Studies of Cost Effective Structures Design for Future Space Systems - Summary

DTIC Science & Technology

1968-06-01

low-cost steels , such as HY-150, in high-pressure tankage for lower stages of launch vehicles. Specific implications are: 1) A new, two-stage Earth...relationships for each of these types obviously differ from one to another. In some cases, structures and mechanisms show similar behaviors . The way...necessary before reuse. Research efforts should also be directed at the configuration and pack- aging of expensive launch vehicle components so that

Comparing marine and terrestrial ecosystems: Implications for the design of coastal marine reserves

USGS Publications Warehouse

Carr, M.H.; Neigel, J.E.; Estes, J.A.; Andelman, S.; Warner, R.R.; Largier, J. L.

2003-01-01

Concepts and theory for the design and application of terrestrial reserves is based on our understanding of environmental, ecological, and evolutionary processes responsible for biological diversity and sustainability of terrestrial ecosystems and how humans have influenced these processes. How well this terrestrial-based theory can be applied toward the design and application of reserves in the coastal marine environment depends, in part, on the degree of similarity between these systems. Several marked differences in ecological and evolutionary processes exist between marine and terrestrial ecosystems as ramifications of fundamental differences in their physical environments (i.e., the relative prevalence of air and water) and contemporary patterns of human impacts. Most notably, the great extent and rate of dispersal of nutrients, materials, holoplanktonic organisms, and reproductive propagules of benthic organisms expand scales of connectivity among near-shore communities and ecosystems. Consequently, the "openness" of marine populations, communities, and ecosystems probably has marked influences on their spatial, genetic, and trophic structures and dynamics in ways experienced by only some terrestrial species. Such differences appear to be particularly significant for the kinds of organisms most exploited and targeted for protection in coastal marine ecosystems (fishes and macroinvertebrates). These and other differences imply some unique design criteria and application of reserves in the marine environment. In explaining the implications of these differences for marine reserve design and application, we identify many of the environmental and ecological processes and design criteria necessary for consideration in the development of the analytical approaches developed elsewhere in this Special Issue.

Schema Theory and Signaling: Implications for Text Design.

ERIC Educational Resources Information Center

Rodriguez, Stephen R.

This discussion of the implications of schema theory and signaling theory for the design of both paper- and computer-based text describes the macro and micro levels of text structure and their interaction, provides a definition of signaling, and identifies four types of signals: (1) pointer words informing the reader of the author's perspective on…

Biofilm formation in an experimental water distribution system: the contamination of non-touch sensor taps and the implication for healthcare.

PubMed

Moore, Ginny; Stevenson, David; Thompson, Katy-Anne; Parks, Simon; Ngabo, Didier; Bennett, Allan M; Walker, Jimmy T

2015-01-01

Hospital tap water is a recognised source of Pseudomonas aeruginosa. U.K. guidance documents recommend measures to control/minimise the risk of P. aeruginosa in augmented care units but these are based on limited scientific evidence. An experimental water distribution system was designed to investigate colonisation of hospital tap components. P. aeruginosa was injected into 27 individual tap 'assemblies'. Taps were subsequently flushed twice daily and contamination levels monitored over two years. Tap assemblies were systematically dismantled and assessed microbiologically and the effect of removing potentially contaminated components was determined. P. aeruginosa was repeatedly recovered from the tap water at levels above the augmented care alert level. The organism was recovered from all dismantled solenoid valves with colonisation of the ethylene propylene diene monomer (EPDM) diaphragm confirmed by microscopy. Removing the solenoid valves reduced P. aeruginosa counts in the water to below detectable levels. This effect was immediate and sustained, implicating the solenoid diaphragm as the primary contamination source.

Appreciating the difference between design-based and model-based sampling strategies in quantitative morphology of the nervous system.

PubMed

Geuna, S

2000-11-20

Quantitative morphology of the nervous system has undergone great developments over recent years, and several new technical procedures have been devised and applied successfully to neuromorphological research. However, a lively debate has arisen on some issues, and a great deal of confusion appears to exist that is definitely responsible for the slow spread of the new techniques among scientists. One such element of confusion is related to uncertainty about the meaning, implications, and advantages of the design-based sampling strategy that characterize the new techniques. In this article, to help remove this uncertainty, morphoquantitative methods are described and contrasted on the basis of the inferential paradigm of the sampling strategy: design-based vs model-based. Moreover, some recommendations are made to help scientists judge the appropriateness of a method used for a given study in relation to its specific goals. Finally, the use of the term stereology to label, more or less expressly, only some methods is critically discussed. Copyright 2000 Wiley-Liss, Inc.

The physics origin of the hierarchy of bodies in space

NASA Astrophysics Data System (ADS)

Bejan, A.; Wagstaff, R. W.

2016-03-01

Here we show that bodies of the same size suspended uniformly in space constitute a system (a "suspension") in a state of uniform volumetric tension because of mass-to-mass forces of attraction. The system "snaps" hierarchically, and evolves faster to a state of reduced tension when the bodies coalesce spontaneously nonuniformly, i.e., hierarchically, into few large and many small bodies suspended in the same space. Hierarchy, not uniformity, is the design that emerges, and it is in accord with the constructal law. The implications of this principle of physics in natural organization and evolution are discussed.

Timber sale planning and analysis system: A user`s guide to the TSPAS sale program. Forest Service general technical report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schuster, E.G.; Jones, J.G.; Meacham, M.L.

1995-08-01

Presents a guide to operation and interpretation of TSPAS Sale Program (TSPAS SP), a menu-driven computer program that is one of two programs in the Timber Sale Planning and Analysis System. TSPAS SP is intended to help field teams design and evaluate timber sale alternatives. TSPAS SP evaluate current and long-term timber implications along with associated nontimber outputs. Features include multiple entries and products, real value change, and graphical input. Guide includes user instructions, a glossary, a listing of data needs, and an explanation of error messages.

Radiation Effects on Emerging Technologies: Implications of Space Weather Risk Management

NASA Technical Reports Server (NTRS)

LaBel, Kenneth A.; Barth, Janet L.

2000-01-01

As NASA and its space partners endeavor to develop a network of satellites capable of supporting humankind's needs for advanced space weather prediction and understanding, one of the key challenges is to design a space system to operate in the natural space radiation environment In this paper, we present a description of the natural space radiation environment, the effects of interest to electronic or photonic systems, and a sample of emerging technologies and their specific issues. We conclude with a discussion of operations in the space radiation hazard and considerations for risk management.

Microphysiological Human Brain and Neural Systems-on-a-Chip: Potential Alternatives to Small Animal Models and Emerging Platforms for Drug Discovery and Personalized Medicine.

PubMed

Haring, Alexander P; Sontheimer, Harald; Johnson, Blake N

2017-06-01

Translational challenges associated with reductionist modeling approaches, as well as ethical concerns and economic implications of small animal testing, drive the need for developing microphysiological neural systems for modeling human neurological diseases, disorders, and injuries. Here, we provide a comprehensive review of microphysiological brain and neural systems-on-a-chip (NSCs) for modeling higher order trajectories in the human nervous system. Societal, economic, and national security impacts of neurological diseases, disorders, and injuries are highlighted to identify critical NSC application spaces. Hierarchical design and manufacturing of NSCs are discussed with distinction for surface- and bulk-based systems. Three broad NSC classes are identified and reviewed: microfluidic NSCs, compartmentalized NSCs, and hydrogel NSCs. Emerging areas and future directions are highlighted, including the application of 3D printing to design and manufacturing of next-generation NSCs, the use of stem cells for constructing patient-specific NSCs, and the application of human NSCs to 'personalized neurology'. Technical hurdles and remaining challenges are discussed. This review identifies the state-of-the-art design methodologies, manufacturing approaches, and performance capabilities of NSCs. This work suggests NSCs appear poised to revolutionize the modeling of human neurological diseases, disorders, and injuries.

Conceptual design of an e-health strategy for the Spanish health care system.

PubMed

González, Marvin E; Quesada, Gioconda; Urrutia, Ignacio; Gavidia, José V

2006-01-01

The purpose of this article is to describe the design and development of an e-health strategy for the Spanish health care system. Using quality function deployment and benchmarking analysis as an analytical model, a strategy in e-health care is proposed. This article uses the case of a Spanish community to build a general framework for e-health system development. Based on a multi-disciplinary literature, and the specific needs of a community, the process of e-health system development is analyzed and reduced into a series of phases that form an integrated method. Best practice managerial techniques are adapted to the healthcare industry and the inter-relationships between them are mapped in a theoretical model that results in the desired outcomes. This analysis produces a road-map to e-health system development consisting of several phases: analysis of the current situation of the system and determination of objectives; collection and analysis of customer expectations; development of an action plan through cross-evaluation of customer and system needs; cost and strategic analyses; and evaluation and control systems. Managerial implications are provided. The strategy proposed in this article is a prototype and an ongoing study in the Castilla-La Mancha community.

Robust synergetic control design under inputs and states constraints

NASA Astrophysics Data System (ADS)

Rastegar, Saeid; Araújo, Rui; Sadati, Jalil

2018-03-01

In this paper, a novel robust-constrained control methodology for discrete-time linear parameter-varying (DT-LPV) systems is proposed based on a synergetic control theory (SCT) approach. It is shown that in DT-LPV systems without uncertainty, and for any unmeasured bounded additive disturbance, the proposed controller accomplishes the goal of stabilising the system by asymptotically driving the error of the controlled variable to a bounded set containing the origin and then maintaining it there. Moreover, given an uncertain DT-LPV system jointly subject to unmeasured and constrained additive disturbances, and constraints in states, input commands and reference signals (set points), then invariant set theory is used to find an appropriate polyhedral robust invariant region in which the proposed control framework is guaranteed to robustly stabilise the closed-loop system. Furthermore, this is achieved even for the case of varying non-zero control set points in such uncertain DT-LPV systems. The controller is characterised to have a simple structure leading to an easy implementation, and a non-complex design process. The effectiveness of the proposed method and the implications of the controller design on feasibility and closed-loop performance are demonstrated through application examples on the temperature control on a continuous-stirred tank reactor plant, on the control of a real-coupled DC motor plant, and on an open-loop unstable system example.

Conceptualizing, Designing, and Investigating Locative Media Use in Urban Space

NASA Astrophysics Data System (ADS)

Diamantaki, Katerina; Rizopoulos, Charalampos; Charitos, Dimitris; Kaimakamis, Nikos

This chapter investigates the social implications of locative media (LM) use and attempts to outline a theoretical framework that may support the design and implementation of location-based applications. Furthermore, it stresses the significance of physical space and location awareness as important factors that influence both human-computer interaction and computer-mediated communication. The chapter documents part of the theoretical aspect of the research undertaken as part of LOcation-based Communication Urban NETwork (LOCUNET), a project that aims to investigate the way users interact with one another (human-computer-human interaction aspect) and with the location-based system itself (human-computer interaction aspect). A number of relevant theoretical approaches are discussed in an attempt to provide a holistic theoretical background for LM use. Additionally, the actual implementation of the LOCUNET system is described and some of the findings are discussed.

Big-Data Based Decision-Support Systems to Improve Clinicians' Cognition.

PubMed

Roosan, Don; Samore, Matthew; Jones, Makoto; Livnat, Yarden; Clutter, Justin

2016-01-01

Complex clinical decision-making could be facilitated by using population health data to inform clinicians. In two previous studies, we interviewed 16 infectious disease experts to understand complex clinical reasoning. For this study, we focused on answers from the experts on how clinical reasoning can be supported by population-based Big-Data. We found cognitive strategies such as trajectory tracking, perspective taking, and metacognition has the potential to improve clinicians' cognition to deal with complex problems. These cognitive strategies could be supported by population health data, and all have important implications for the design of Big-Data based decision-support tools that could be embedded in electronic health records. Our findings provide directions for task allocation and design of decision-support applications for health care industry development of Big data based decision-support systems.

Big-Data Based Decision-Support Systems to Improve Clinicians’ Cognition

PubMed Central

Roosan, Don; Samore, Matthew; Jones, Makoto; Livnat, Yarden; Clutter, Justin

2016-01-01

Complex clinical decision-making could be facilitated by using population health data to inform clinicians. In two previous studies, we interviewed 16 infectious disease experts to understand complex clinical reasoning. For this study, we focused on answers from the experts on how clinical reasoning can be supported by population-based Big-Data. We found cognitive strategies such as trajectory tracking, perspective taking, and metacognition has the potential to improve clinicians’ cognition to deal with complex problems. These cognitive strategies could be supported by population health data, and all have important implications for the design of Big-Data based decision-support tools that could be embedded in electronic health records. Our findings provide directions for task allocation and design of decision-support applications for health care industry development of Big data based decision-support systems. PMID:27990498

From infancy to adolescence: the development and future of the national firefighter near-miss reporting system.

PubMed

Taylor, Jennifer A; Lacovara, Alicia V

2015-02-01

The National Fire Fighter Near-Miss Reporting System (NFFNMRS) is a voluntary adverse event reporting system designed as a repository to which firefighters submit information on the hazards seen in their work, detailing the events that led to near-misses and injuries. This descriptive article discusses the development of the system since its inception, the strengths and limitations of the resultant data, and the improvements to be made to ensure the system's usefulness. Especially in their infancy, near-miss systems are very dependent on funding and sensitive to any reductions as they head toward steady-state reporting. This sustainability factor has significant implications for continued reporting to the system and the ultimate utility of the data. Very few such data systems exist for occupational health surveillance. © 2015 SAGE Publications.

Sustainable urban systems: Co-design and framing for transformation.

PubMed

Webb, Robert; Bai, Xuemei; Smith, Mark Stafford; Costanza, Robert; Griggs, David; Moglia, Magnus; Neuman, Michael; Newman, Peter; Newton, Peter; Norman, Barbara; Ryan, Chris; Schandl, Heinz; Steffen, Will; Tapper, Nigel; Thomson, Giles

2018-02-01

Rapid urbanisation generates risks and opportunities for sustainable development. Urban policy and decision makers are challenged by the complexity of cities as social-ecological-technical systems. Consequently there is an increasing need for collaborative knowledge development that supports a whole-of-system view, and transformational change at multiple scales. Such holistic urban approaches are rare in practice. A co-design process involving researchers, practitioners and other stakeholders, has progressed such an approach in the Australian context, aiming to also contribute to international knowledge development and sharing. This process has generated three outputs: (1) a shared framework to support more systematic knowledge development and use, (2) identification of barriers that create a gap between stated urban goals and actual practice, and (3) identification of strategic focal areas to address this gap. Developing integrated strategies at broader urban scales is seen as the most pressing need. The knowledge framework adopts a systems perspective that incorporates the many urban trade-offs and synergies revealed by a systems view. Broader implications are drawn for policy and decision makers, for researchers and for a shared forward agenda.

The Design of Collectives of Agents to Control Non-Markovian Systems

NASA Technical Reports Server (NTRS)

Lawson, John W.; Wolpert, David H.

2004-01-01

The Collective Intelligence (COIN) framework concerns the design of collectives of reinforcement-learning agents such that their interaction causes a provided "world" utility function concerning the entire collective to be maximized. Previously, we applied that framework to scenarios involving Markovian dynamics where no re-evolution of the system from counter-factual initial conditions (an often expensive calculation) is permitted. This approach sets the individual utility function of each agent to be both aligned with the world utility, and at the same time, easy for the associated agents to optimize. Here we extend that approach to systems involving non-Markovian dynamics. In computer simulations, we compare our techniques with each other and with conventional "team games". We show whereas in team games performance often degrades badly with time, it steadily improves when our techniques are used. We also investigate situations where the system's dimensionality is effectively reduced. We show that this leads to difficulties in the agents ability to learn. The implication is that learning is a property only of high-enough dimensional systems.

A novel retinoic acid, catechin hydrate and mustard oil-based emulsion for enhanced cytokine and antibody responses against multiple strains of HIV-1 following mucosal and systemic vaccinations

PubMed Central

Yu, Mingke; Vajdy, Michael

2011-01-01

Non-replicating protein- or DNA-based antigens generally require immune-enhancing adjuvants and delivery systems. It has been particularly difficult to raise antibodies against gp120 of HIV-1, which constitutes an important approach in HIV vaccine design. While almost all effort in adjuvant research has focused on mimicking the pathogens and the danger signals they engender in the host, relatively little effort has been spent on nutritive approaches. In this study, a new nutritive immune-enhancing delivery system (NIDS) composed of vitamin A, a polyphenol-flavonoid catechin hydrate, and mustard oil was tested for its adjuvant effect in immune responses against the gp120 protein of HIV-1CN54. Following a combination of two mucosal and two systemic vaccinations of mice, we found significant enhancement of both local and systemic antibodies as well as cytokine responses. These data have important implications for vaccine and adjuvant design against HIV-1 and other pathogens. PMID:21272602

The Design of Collectives of Agents to Control Non-Markovian Systems

NASA Technical Reports Server (NTRS)

Lawson, John W.; Wolpert, David H.; Clancy, Daniel (Technical Monitor)

2002-01-01

The 'Collective Intelligence' (COIN) framework concerns the design of collectives of reinforcement-learning agents such that their interaction causes a provided 'world' utility function concerning the entire collective to be maximized. Previously, we applied that framework to scenarios involving Markovian dynamics where no re-evolution of the system from counter-factual initial conditions (an often expensive calculation) is permitted. This approach sets the individual utility function of each agent to be both aligned with the world utility, and at the same time, easy for the associated agents to optimize. Here we extend that approach to systems involving non-Markovian dynamics. In computer simulations, we compare our techniques with each other and with conventional-'team games'. We show whereas in team games performance often degrades badly with time, it steadily improves when our techniques are used. We also investigate situations where the system's dimensionality is effectively reduced. We show that this leads to difficulties in the agents' ability to learn. The implication is that 'learning' is a property only of high-enough dimensional systems.

Object reasoning for waste remediation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pennock, K.A.; Bohn, S.J.; Franklin, A.L.

1991-08-01

A large number of contaminated waste sites across the United States await size remediation efforts. These sites can be physically complex, composed of multiple, possibly interacting, contaminants distributed throughout one or more media. The Remedial Action Assessment System (RAAS) is being designed and developed to support decisions concerning the selection of remediation alternatives. The goal of this system is to broaden the consideration of remediation alternatives, while reducing the time and cost of making these considerations. The Remedial Action Assessment System is a hybrid system, designed and constructed using object-oriented, knowledge- based systems, and structured programming techniques. RAAS uses amore » combination of quantitative and qualitative reasoning to consider and suggest remediation alternatives. The reasoning process that drives this application is centered around an object-oriented organization of remediation technology information. This paper describes the information structure and organization used to support this reasoning process. In addition, the paper describes the level of detail of the technology related information used in RAAS, discusses required assumptions and procedural implications of these assumptions, and provides rationale for structuring RAAS in this manner. 3 refs., 3 figs.« less

Design of Composite Structures Using Knowledge-Based and Case Based Reasoning

NASA Technical Reports Server (NTRS)

Lambright, Jonathan Paul

1996-01-01

A method of using knowledge based and case based reasoning to assist designers during conceptual design tasks of composite structures was proposed. The cooperative use of heuristics, procedural knowledge, and previous similar design cases suggests a potential reduction in design cycle time and ultimately product lead time. The hypothesis of this work is that the design process of composite structures can be improved by using Case-Based Reasoning (CBR) and Knowledge-Based (KB) reasoning in the early design stages. The technique of using knowledge-based and case-based reasoning facilitates the gathering of disparate information into one location that is easily and readily available. The method suggests that the inclusion of downstream life-cycle issues into the conceptual design phase reduces potential of defective, and sub-optimal composite structures. Three industry experts were interviewed extensively. The experts provided design rules, previous design cases, and test problems. A Knowledge Based Reasoning system was developed using the CLIPS (C Language Interpretive Procedural System) environment and a Case Based Reasoning System was developed using the Design Memory Utility For Sharing Experiences (MUSE) xviii environment. A Design Characteristic State (DCS) was used to document the design specifications, constraints, and problem areas using attribute-value pair relationships. The DCS provided consistent design information between the knowledge base and case base. Results indicated that the use of knowledge based and case based reasoning provided a robust design environment for composite structures. The knowledge base provided design guidance from well defined rules and procedural knowledge. The case base provided suggestions on design and manufacturing techniques based on previous similar designs and warnings of potential problems and pitfalls. The case base complemented the knowledge base and extended the problem solving capability beyond the existence of limited well defined rules. The findings indicated that the technique is most effective when used as a design aid and not as a tool to totally automate the composites design process. Other areas of application and implications for future research are discussed.

Transforming long-term care pain management in north america: the policy-clinical interface.

PubMed

Hadjistavropoulos, Thomas; Marchildon, Gregory P; Fine, Perry G; Herr, Keela; Palley, Howard A; Kaasalainen, Sharon; Béland, François

2009-04-01

The undertreatment of pain in older adults who reside in long-term care (LTC) facilities has been well documented, leading to clinical guideline development and professional educational programs designed to foster better pain assessment and management in this population. Despite these efforts, little improvement has occurred, and we postulate that focused attention to public policy and cost implications of systemic change is required to create positive pain-related outcomes. Our goal was to outline feasible and cost-effective clinical and public policy recommendations designed to address the undermanagement of pain in LTC facilities. We arranged a 2-day consensus meeting of prominent United States and Canadian pain and public policy experts. An initial document describing the problem of pain undermanagement in LTC was developed and circulated prior to the meeting. Participants were also asked to respond to a list of relevant questions before arriving. Following formal presentations of a variety of proposals and extensive discussion among clinicians and policy experts, a set of recommendations was developed. We outline key elements of a transformational model of pain management in LTC for the United States and Canada. Consistent with previously formulated clinical guidelines but with attention to readily implementable public policy change in both countries, this transformational model of LTC has important implications for LTC managers and policy makers as well as major quality of life implications for LTC residents.

Abrupt climate change: can society cope?

PubMed

Hulme, Mike

2003-09-15

Consideration of abrupt climate change has generally been incorporated neither in analyses of climate-change impacts nor in the design of climate adaptation strategies. Yet the possibility of abrupt climate change triggered by human perturbation of the climate system is used to support the position of both those who urge stronger and earlier mitigative action than is currently being contemplated and those who argue that the unknowns in the Earth system are too large to justify such early action. This paper explores the question of abrupt climate change in terms of its potential implications for society, focusing on the UK and northwest Europe in particular. The nature of abrupt climate change and the different ways in which it has been defined and perceived are examined. Using the example of the collapse of the thermohaline circulation (THC), the suggested implications for society of abrupt climate change are reviewed; previous work has been largely speculative and has generally considered the implications only from economic and ecological perspectives. Some observations about the implications from a more social and behavioural science perspective are made. If abrupt climate change simply implies changes in the occurrence or intensity of extreme weather events, or an accelerated unidirectional change in climate, the design of adaptation to climate change can proceed within the existing paradigm, with appropriate adjustments. Limits to adaptation in some sectors or regions may be reached, and the costs of appropriate adaptive behaviour may be large, but strategy can develop on the basis of a predicted long-term unidirectional change in climate. It would be more challenging, however, if abrupt climate change implied a directional change in climate, as, for example, may well occur in northwest Europe following a collapse of the THC. There are two fundamental problems for society associated with such an outcome: first, the future changes in climate currently being anticipated and prepared for may reverse and, second, the probability of such a scenario occurring remains fundamentally unknown. The implications of both problems for climate policy and for decision making have not been researched. It is premature to argue therefore that abrupt climate change - in the sense referred to here - imposes unacceptable costs on society or the world economy, represents a catastrophic impact of climate change or constitutes a dangerous change in climate that should be avoided at all reasonable cost. We conclude by examining the implications of this contention for future research and policy formation.

Green buildings: Implications for acousticians

NASA Astrophysics Data System (ADS)

Noble, Michael R.

2005-04-01

This presentation will deal with the practical implications of green design protocols of the US Green Building Council on interior acoustics of buildings. Three areas of particular consequence to acousticians will be discussed. Ventilation Systems: reduced energy consumption goals dictate reliance on natural cooling and ventilation using ambient air when possible. The consequent large openings in the building envelope to bring fresh air into rooms, and similar sized openings to transfer the mixed air out, can severely compromise the noise isolation of the rooms concerned. Radiant Cooling: the heavy concrete floors of buildings can be used as a thermal flywheel to lessen the cooling load, which forces the concrete ceilings to be exposed to the occupied rooms for heat transfer, and strictly limits the application of acoustical absorption on the ceilings. This challenges the room acoustics design. Green Materials: the LEED protocols require the elimination of potentially harmful finishes, including fibrous materials which may impact air quality or contribute to health problems. Since the backbone of sound absorption is glass and mineral fibres, this further challenges provision of superior room acoustics. Examples and commentary will be provided based on current and recent projects.

Optical analysis of laser systems using interferometry

NASA Astrophysics Data System (ADS)

Viswanathan, V. K.; Liberman, I.; Lawrence, G.; Seery, B. D.

1980-06-01

It is noted that previous approaches of predicting focal spot parameters involved the digitization of interference patterns of the optical components and propagation of the complex amplitude and phase of the wave front throughout the system. The present paper describes an approach in which the computational procedure is extended to produce computer plots of the final emerging wave front. It is shown that this enables direct comparison with the experimentally produced wave front of the total system and makes possible the optical analysis, design, and possible optimization of laser systems. A description is given of the computational procedure and the Twyman-Green and Smartt IR interferometers constructed to verify this approach. Finally, consideration is given to the implications of the results.

System implications of large radiometric array antennas

NASA Technical Reports Server (NTRS)

Levis, C. A.; Lin, H. C.

1976-01-01

Current radiometric earth and atmospheric sensing systems in the centimeter wavelength range generally employ a directive antenna connected through a single terminal pair to a Dicke receiver. It is shown that this approach does not lend itself to systems with greatly increased spatial resolution. Signal to noise considerations relating to antenna efficiency force the introduction of active elements at the subarray level; thus, if Dicke switching is to be used, it must be distributed throughout the system. Some possible approaches are suggested. The introduction of active elements at the subarray level is found to ease the design constraints on time delay elements, necessary for bandwidth, and on multiple beam generation, required in order to achieve sufficient integration time with high resolution.

Practicality of electronic beam steering for MST/ST radars, part 6.2A

NASA Technical Reports Server (NTRS)

Clark, W. L.; Green, J. L.

1984-01-01

Electronic beam steering is described as complex and expensive. The Sunset implementation of electronic steering is described, and it is demonstrated that such systems are cost effective, versatile, and no more complex than fixed beam alternatives, provided three or more beams are needed. The problem of determining accurate meteorological wind components in the presence of spatial variation is considered. A cost comparison of steerable and fixed systems allowing solution of this problem is given. The concepts and relations involved in phase steering are given, followed by the description of the Sunset ST radar steering system. The implications are discussed, references to the competing SAD method are provided, and a recommendation concerning the design of the future Doppler ST/MST systems is made.

Cost Scaling of a Real-World Exhaust Waste Heat Recovery Thermoelectric Generator: A Deeper Dive

NASA Astrophysics Data System (ADS)

Hendricks, Terry J.; Yee, Shannon; LeBlanc, Saniya

2016-03-01

Cost is equally important to power density or efficiency for the adoption of waste heat recovery thermoelectric generators (TEG) in many transportation and industrial energy recovery applications. In many cases, the system design that minimizes cost (e.g., the /W value) can be very different than the design that maximizes the system's efficiency or power density, and it is important to understand the relationship between those designs to optimize TEG performance-cost compromises. Expanding on recent cost analysis work and using more detailed system modeling, an enhanced cost scaling analysis of a waste heat recovery TEG with more detailed, coupled treatment of the heat exchangers has been performed. In this analysis, the effect of the heat lost to the environment and updated relationships between the hot-side and cold-side conductances that maximize power output are considered. This coupled thermal and thermoelectric (TE) treatment of the exhaust waste heat recovery TEG yields modified cost scaling and design optimization equations, which are now strongly dependent on the heat leakage fraction, exhaust mass flow rate, and heat exchanger effectiveness. This work shows that heat exchanger costs most often dominate the overall TE system costs, that it is extremely difficult to escape this regime, and in order to achieve TE system costs of 1/W it is necessary to achieve heat exchanger costs of 1/(W/K). Minimum TE system costs per watt generally coincide with maximum power points, but preferred TE design regimes are identified where there is little cost penalty for moving into regions of higher efficiency and slightly lower power outputs. These regimes are closely tied to previously identified low cost design regimes. This work shows that the optimum fill factor F opt minimizing system costs decreases as heat losses increase, and increases as exhaust mass flow rate and heat exchanger effectiveness increase. These findings have profound implications on the design and operation of various TE waste heat recovery systems. This work highlights the importance of heat exchanger costs on the overall TEG system costs, quantifies the possible TEG performance-cost domain space based on heat exchanger effects, and provides a focus for future system research and development efforts.

The Role of the Built Environment: How Decentralized Nurse Stations Shape Communication, Patient Care Processes, and Patient Outcomes.

PubMed

Real, Kevin; Bardach, Shoshana H; Bardach, David R

2017-12-01

Increasingly, health communication scholars are attending to how hospital built environments shape communication, patient care processes, and patient outcomes. This multimethod study was conducted on two floors of a newly designed urban hospital. Nine focus groups interviews were conducted with 35 health care professionals from 10 provider groups. Seven of the groups were homogeneous by profession or level: nursing (three groups), nurse managers (two groups), and one group each of nurse care technicians ("techs") and physicians. Two mixed groups were comprised of staff from pharmacy, occupational therapy, patient care facilitators, physical therapy, social work, and pastoral care. Systematic qualitative analysis was conducted using a conceptual framework based on systems theory and prior health care design and communication research. Additionally, quantitative modeling was employed to assess walking distances in two different hospital designs. Results indicate nurses walked significantly more in the new hospital environment. Qualitative analysis revealed three insights developed in relationship to system structures, processes, and outcomes. First, decentralized nurse stations changed system interdependencies by reducing nurse-to-nurse interactions and teamwork while heightening nurse interdependencies and teamwork with other health care occupations. Second, many nursing-related processes remained centralized while nurse stations were decentralized, creating systems-based problems for nursing care. Third, nursing communities of practices were adversely affected by the new design. Implications of this study suggest that nurse station design shapes communication, patient care processes, and patient outcomes. Further, it is important to understand how the built environment, often treated as invisible in communication research, is crucial to understanding communication within complex health care systems.

Healthcare waste management: an interpretive structural modeling approach.

PubMed

Thakur, Vikas; Anbanandam, Ramesh

2016-06-13

Purpose - The World Health Organization identified infectious healthcare waste as a threat to the environment and human health. India's current medical waste management system has limitations, which lead to ineffective and inefficient waste handling practices. Hence, the purpose of this paper is to: first, identify the important barriers that hinder India's healthcare waste management (HCWM) systems; second, classify operational, tactical and strategical issues to discuss the managerial implications at different management levels; and third, define all barriers into four quadrants depending upon their driving and dependence power. Design/methodology/approach - India's HCWM system barriers were identified through the literature, field surveys and brainstorming sessions. Interrelationships among all the barriers were analyzed using interpretive structural modeling (ISM). Fuzzy-Matrice d'Impacts Croisés Multiplication Appliquée á un Classement (MICMAC) analysis was used to classify HCWM barriers into four groups. Findings - In total, 25 HCWM system barriers were identified and placed in 12 different ISM model hierarchy levels. Fuzzy-MICMAC analysis placed eight barriers in the second quadrant, five in third and 12 in fourth quadrant to define their relative ISM model importance. Research limitations/implications - The study's main limitation is that all the barriers were identified through a field survey and barnstorming sessions conducted only in Uttarakhand, Northern State, India. The problems in implementing HCWM practices may differ with the region, hence, the current study needs to be replicated in different Indian states to define the waste disposal strategies for hospitals. Practical implications - The model will help hospital managers and Pollution Control Boards, to plan their resources accordingly and make policies, targeting key performance areas. Originality/value - The study is the first attempt to identify India's HCWM system barriers and prioritize them.

Towards Behavioral Reflexion Models

NASA Technical Reports Server (NTRS)

Ackermann, Christopher; Lindvall, Mikael; Cleaveland, Rance

2009-01-01

Software architecture has become essential in the struggle to manage today s increasingly large and complex systems. Software architecture views are created to capture important system characteristics on an abstract and, thus, comprehensible level. As the system is implemented and later maintained, it often deviates from the original design specification. Such deviations can have implication for the quality of the system, such as reliability, security, and maintainability. Software architecture compliance checking approaches, such as the reflexion model technique, have been proposed to address this issue by comparing the implementation to a model of the systems architecture design. However, architecture compliance checking approaches focus solely on structural characteristics and ignore behavioral conformance. This is especially an issue in Systems-of- Systems. Systems-of-Systems (SoS) are decompositions of large systems, into smaller systems for the sake of flexibility. Deviations of the implementation to its behavioral design often reduce the reliability of the entire SoS. An approach is needed that supports the reasoning about behavioral conformance on architecture level. In order to address this issue, we have developed an approach for comparing the implementation of a SoS to an architecture model of its behavioral design. The approach follows the idea of reflexion models and adopts it to support the compliance checking of behaviors. In this paper, we focus on sequencing properties as they play an important role in many SoS. Sequencing deviations potentially have a severe impact on the SoS correctness and qualities. The desired behavioral specification is defined in UML sequence diagram notation and behaviors are extracted from the SoS implementation. The behaviors are then mapped to the model of the desired behavior and the two are compared. Finally, a reflexion model is constructed that shows the deviations between behavioral design and implementation. This paper discusses the approach and shows how it can be applied to investigate reliability issues in SoS.

Racial progress as threat to the status hierarchy: implications for perceptions of anti-White bias.

PubMed

Wilkins, Clara L; Kaiser, Cheryl R

2014-02-01

In three studies, we examined how racial progress affects Whites' perceptions of anti-White bias. When racial progress was chronically (Study 1) and experimentally (Study 2) salient, Whites who believed the current U.S. status hierarchy was legitimate were more likely to report that Whites were victims of racial discrimination. In contrast, Whites who perceived the current status system as illegitimate were unaffected by the salience of racial progress. The results of Study 3 point to the role of threat in explaining these divergent reactions to racial progress. When self-affirmed, Whites who perceived the status hierarchy as legitimate no longer showed increased perceptions of anti-White bias when confronted with evidence of racial progress. Implications for policies designed to remedy social inequality are discussed.

Implications of the degree of controllability of controlled plants in the sense of LQR optimal control

NASA Astrophysics Data System (ADS)

Xia, Yaping; Yin, Minghui; Zou, Yun

2018-01-01

In this paper, the relationship between the degree of controllability (DOC) of controlled plants and the corresponding quadratic optimal performance index in LQR control is investigated for the electro-hydraulic synchronising servo control systems and wind turbine systems, respectively. It is shown that for these two types of systems, the higher the DOC of a controlled plant is, the better the quadratic optimal performance index is. It implies that in some LQR controller designs, the measure of the DOC of a controlled plant can be used as an index for the optimisation of adjustable plant parameters, by which the plant can be controlled more effectively.

Micro sensor node for air pollutant monitoring: hardware and software issues.

PubMed

Choi, Sukwon; Kim, Nakyoung; Cha, Hojung; Ha, Rhan

2009-01-01

Wireless sensor networks equipped with various gas sensors have been actively used for air quality monitoring. Previous studies have typically explored system issues that include middleware or networking performance, but most research has barely considered the details of the hardware and software of the sensor node itself. In this paper, we focus on the design and implementation of a sensor board for air pollutant monitoring applications. Several hardware and software issues are discussed to explore the possibilities of a practical WSN-based air pollution monitoring system. Through extensive experiments and evaluation, we have determined the various characteristics of the gas sensors and their practical implications for air pollutant monitoring systems.

New approaches for real time decision support systems

NASA Technical Reports Server (NTRS)

Hair, D. Charles; Pickslay, Kent

1994-01-01

NCCOSC RDT&E Division (NRaD) is conducting research into ways of improving decision support systems (DSS) that are used in tactical Navy decision making situations. The research has focused on the incorporation of findings about naturalistic decision-making processes into the design of the DSS. As part of that research, two computer tools were developed that model the two primary naturalistic decision-making strategies used by Navy experts in tactical settings. Current work is exploring how best to incorporate the information produced by those tools into an existing simulation of current Navy decision support systems. This work has implications for any applications involving the need to make decisions under time constraints, based on incomplete or ambiguous data.

From discovery to licensure, the Adjuvant System story.

PubMed

Garçon, Nathalie; Di Pasquale, Alberta

2017-01-02

Adjuvants are substances added to vaccines to improve their immunogenicity. Used for more than 80 years, aluminum, the first adjuvant in human vaccines, proved insufficient to develop vaccines that could protect against new challenging pathogens such as HIV and malaria. New adjuvants and new combinations of adjuvants (Adjuvant Systems) have opened the door to the delivery of improved and new vaccines against re-emerging and difficult pathogens. Adjuvant Systems concept started through serendipity. The access to new developments in technology, microbiology and immunology have been instrumental for the dicephering of what they do and how they do it. This knowledge opens the door to more rational vaccine design with implications for developing new and better vaccines.

Direct atomic force microscopy observation of DNA tile crystal growth at the single-molecule level.

PubMed

Evans, Constantine G; Hariadi, Rizal F; Winfree, Erik

2012-06-27

While the theoretical implications of models of DNA tile self-assembly have been extensively researched and such models have been used to design DNA tile systems for use in experiments, there has been little research testing the fundamental assumptions of those models. In this paper, we use direct observation of individual tile attachments and detachments of two DNA tile systems on a mica surface imaged with an atomic force microscope (AFM) to compile statistics of tile attachments and detachments. We show that these statistics fit the widely used kinetic Tile Assembly Model and demonstrate AFM movies as a viable technique for directly investigating DNA tile systems during growth rather than after assembly.

Policy Implications Analysis: A Methodological Advancement for Policy Research and Evaluation.

ERIC Educational Resources Information Center

Madey, Doren L.; Stenner, A. Jackson

Policy Implications Analysis (PIA) is a tool designed to maximize the likelihood that an evaluation report will have an impact on decision-making. PIA was designed to help people planning and conducting evaluations tailor their information so that it has optimal potential for being used and acted upon. This paper describes the development and…

Multi-unit Operations in Non-Nuclear Systems: Lessons Learned for Small Modular Reactors

DOE Office of Scientific and Technical Information (OSTI.GOV)

OHara J. M.; Higgins, J.; DAgostino, A.

2012-01-17

The nuclear-power community has reached the stage of proposing advanced reactor designs to support power generation for decades to come. Small modular reactors (SMRs) are one approach to meet these energy needs. While the power output of individual reactor modules is relatively small, they can be grouped to produce reactor sites with different outputs. Also, they can be designed to generate hydrogen, or to process heat. Many characteristics of SMRs are quite different from those of current plants and may be operated quite differently. One difference is that multiple units may be operated by a single crew (or a singlemore » operator) from one control room. The U.S. Nuclear Regulatory Commission (NRC) is examining the human factors engineering (HFE) aspects of SMRs to support licensing reviews. While we reviewed information on SMR designs to obtain information, the designs are not completed and all of the design and operational information is not yet available. Nor is there information on multi-unit operations as envisioned for SMRs available in operating experience. Thus, to gain a better understanding of multi-unit operations we sought the lesson learned from non-nuclear systems that have experience in multi-unit operations, specifically refineries, unmanned aerial vehicles and tele-intensive care units. In this paper we report the lessons learned from these systems and the implications for SMRs.« less

Shuttle-tethered satellite system definition study extension

NASA Technical Reports Server (NTRS)

1980-01-01

A system requirements definition and configuration study (Phase B) of the Tethered Satellite System (TSS) was conducted during the period 14 November 1977 to 27 February 1979. Subsequently a study extension was conducted during the period 13 June 1979 to 30 June 1980, for the purpose of refining the requirements identified during the main phase of the study, and studying in some detail the implications of accommodating various types of scientific experiments on the initial verification flight mission. An executive overview is given of the Tethered Satellite System definition developed during the study. The results of specific study tasks undertaken in the extension phase of the study are reported. Feasibility of the Tethered Satellite System has been established with reasonable confidence and the groundwork laid for proceeding with hardware design for the verification mission.

Overview of Risk Mitigation for Safety-Critical Computer-Based Systems

NASA Technical Reports Server (NTRS)

Torres-Pomales, Wilfredo

2015-01-01

This report presents a high-level overview of a general strategy to mitigate the risks from threats to safety-critical computer-based systems. In this context, a safety threat is a process or phenomenon that can cause operational safety hazards in the form of computational system failures. This report is intended to provide insight into the safety-risk mitigation problem and the characteristics of potential solutions. The limitations of the general risk mitigation strategy are discussed and some options to overcome these limitations are provided. This work is part of an ongoing effort to enable well-founded assurance of safety-related properties of complex safety-critical computer-based aircraft systems by developing an effective capability to model and reason about the safety implications of system requirements and design.

Integrated heat exchanger design for a cryogenic storage tank

NASA Astrophysics Data System (ADS)

Fesmire, J. E.; Tomsik, T. M.; Bonner, T.; Oliveira, J. M.; Conyers, H. J.; Johnson, W. L.; Notardonato, W. U.

2014-01-01

Field demonstrations of liquid hydrogen technology will be undertaken for the proliferation of advanced methods and applications in the use of cryofuels. Advancements in the use of cryofuels for transportation on Earth, from Earth, or in space are envisioned for automobiles, aircraft, rockets, and spacecraft. These advancements rely on practical ways of storage, transfer, and handling of liquid hydrogen. Focusing on storage, an integrated heat exchanger system has been designed for incorporation with an existing storage tank and a reverse Brayton cycle helium refrigerator of capacity 850 watts at 20 K. The storage tank is a 125,000-liter capacity horizontal cylindrical tank, with vacuum jacket and multilayer insulation, and a small 0.6-meter diameter manway opening. Addressed are the specific design challenges associated with the small opening, complete modularity, pressure systems re-certification for lower temperature and pressure service associated with hydrogen densification, and a large 8:1 length-to-diameter ratio for distribution of the cryogenic refrigeration. The approach, problem solving, and system design and analysis for integrated heat exchanger are detailed and discussed. Implications for future space launch facilities are also identified. The objective of the field demonstration will be to test various zero-loss and densified cryofuel handling concepts for future transportation applications.

Integrated heat exchanger design for a cryogenic storage tank

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fesmire, J. E.; Bonner, T.; Oliveira, J. M.

Field demonstrations of liquid hydrogen technology will be undertaken for the proliferation of advanced methods and applications in the use of cryofuels. Advancements in the use of cryofuels for transportation on Earth, from Earth, or in space are envisioned for automobiles, aircraft, rockets, and spacecraft. These advancements rely on practical ways of storage, transfer, and handling of liquid hydrogen. Focusing on storage, an integrated heat exchanger system has been designed for incorporation with an existing storage tank and a reverse Brayton cycle helium refrigerator of capacity 850 watts at 20 K. The storage tank is a 125,000-liter capacity horizontal cylindricalmore » tank, with vacuum jacket and multilayer insulation, and a small 0.6-meter diameter manway opening. Addressed are the specific design challenges associated with the small opening, complete modularity, pressure systems re-certification for lower temperature and pressure service associated with hydrogen densification, and a large 8:1 length-to-diameter ratio for distribution of the cryogenic refrigeration. The approach, problem solving, and system design and analysis for integrated heat exchanger are detailed and discussed. Implications for future space launch facilities are also identified. The objective of the field demonstration will be to test various zero-loss and densified cryofuel handling concepts for future transportation applications.« less

Space-based multifunctional end effector systems functional requirements and proposed designs

NASA Technical Reports Server (NTRS)

Mishkin, A. H.; Jau, B. M.

1988-01-01

The end effector is an essential element of teleoperator and telerobot systems to be employed in space in the next decade. The report defines functional requirements for end effector systems to perform operations that are currently only feasible through Extra-Vehicular Activity (EVA). Specific tasks and functions that the end effectors must be capable of performing are delineated. Required capabilities for forces and torques, clearances, compliance, and sensing are described, using current EVA requirements as guidelines where feasible. The implications of these functional requirements on the elements of potential end effector systems are discussed. The systems issues that must be considered in the design of space-based manipulator systems are identified; including impacts on subsystems tightly coupled to the end effector, i.e., control station, information processing, manipulator arm, tool and equipment stowage. Possible end effector designs are divided into three categories: single degree-of-freedom end effectors, multiple degree of freedom end effectors, and anthropomorphic hands. Specific design alternatives are suggested and analyzed within the individual categories. Two evaluations are performed: the first considers how well the individual end effectors could substitute for EVA; the second compares how manipulator systems composed of the top performers from the first evaluation would improve the space shuttle Remote Manipulator System (RMS) capabilities. The analysis concludes that the anthropomorphic hand is best-suited for EVA tasks. A left- and right-handed anthropomorphic manipulator arm configuration is suggested as appropriate to be affixed to the RMS, but could also be used as part of the Smart Front End for the Orbital Maneuvering Vehicle (OMV). The technical feasibility of the anthropomorphic hand and its control are demonstrated. An evolutionary development approach is proposed and approximate scheduling provided for implementing the suggested manipulator systems in time for space stations operations in the early 1990s.

Lunar lander stage requirements based on the Civil Needs Data Base

NASA Technical Reports Server (NTRS)

Mulqueen, John A.

1992-01-01

This paper examines the lunar lander stages that will be necessary for the future exploration and development of the Moon. Lunar lander stage sizing is discussed based on the projected lunar payloads listed in the Civil Needs Data Base. Factors that will influence the lander stage design are identified and discussed. Some of these factors are (1) lunar orbiting and lunar surface lander bases; (2) implications of direct landing trajectories and landing from a parking orbit; (3) implications of landing site and parking orbit; (4) implications of landing site and parking orbit selection; (5) the use of expendable and reusable lander stages; and (6) the descent/ascent trajectories. Data relating the lunar lander stage design requirements to each of the above factors and others are presented in parametric form. These data will provide useful design data that will be applicable to future mission model modifications and design studies.

The Microchip Revolution: Implications for Education.

ERIC Educational Resources Information Center

Small, Michele Geslin

1984-01-01

Discusses positive and negative implications of microcomputer technology for teachers and students; how this technology will facilitate barrier breakdown between school and society; possible political implications; and how the principles of anticipation, design, and planning will facilitate a smooth transitional course in school and society. (MBR)

International Pacific Air and Space Technology Conference and Aircraft Symposium, 29th, Gifu, Japan, Oct. 7-11, 1991, Proceedings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-01-01

Various papers on air and space technology are presented. Individual topics addressed include: media selection analysis: implications for training design, high-speed challenge for rotary wing aircraft, high-speed VSTOL answer to congestion, next generation in computational aerodynamics, acrobatic airship 'Acrostat', ducted fan VTOL for working platform, Arianespace launch of Lightsats, small particle acceleration by minirailgun, free-wake analyses of a hovering rotor using panel method, update of the X-29 high-angle-of-attack program, economic approach to accurate wing design, flow field around thick delta wing with rounded leading edge, aerostructural integrated design of forward-swept wing, static characteristics of a two-phase fluid drop system, simplfied-modelmore » approach to group combustion of fuel spray, avionics flight systems for the 21st century. Also discussed are: Aircraft Command in Emergency Situations, spectrogram diagnosis of aircraft disasters, shock interaction induced by two hemisphere-cylinders, impact response of composite UHB propeller blades, high-altitude lighter-than-air powered platform, integrated wiring system, auxiliary power units for current and future aircraft, Space Shuttle Orbiter Auxiliary Power Unit status, numerical analysis of RCS jet in hypersonic flights, energy requirements for the space frontier, electrical system options for space exploration, aerospace plane hydrogen scramjet boosting, manual control of vehicles with time-varying dynamics, design of strongly stabilizing controller, development of the Liquid Apogee Propulsion System for ETS-VI.« less

Student Learning Assessment and the Curriculum: Issues and Implications for Policy, Design and Implementation. In-Progress Reflections No. 1 on "Current and Critical Issues in the Curriculum and Learning"

ERIC Educational Resources Information Center

Muskin, Joshua A.

2015-01-01

The role of assessment in education has grown greatly over the past few decades, a trend that has two major manifestations. One is the rapid increase in the number of countries and other jurisdictions either participating in international surveys (tests) of learning or initiating their own system-wide assessments; or both. The other is the…

Design and System Implications of a Family of Wideband HF Data Waveforms

DTIC Science & Technology

2010-09-01

code rates (i.e. 8/9, 9/10) will be used to attain the highest data rates for surface wave links. Very high puncturing of convolutional codes can...Communication Links”, Edition 1, North Atlantic Treaty Organization, 2009. [14] Yasuda, Y., Kashiki, K., Hirata, Y. “High- Rate Punctured Convolutional Codes ...length 7 convolutional code that has been used for over two decades in 110A. In addition, repetition coding and puncturing was

Management Information Systems Design Implications: The Effect of Cognitive Style and Information Presentation on Problem Solving.

DTIC Science & Technology

1987-12-01

my thesis advisor, Dr Dennis E Campbell. Without his expert advice and extreme patience with an INTP like myself, this research would not have been...research was to identify a relationship between psychological type and mode of presentation of information. The * type theory developed ty Carl Jung and...preference rankings for seven differewnt modes of presentation of data. The statistical analyses showed no relationship betveen personality type and

Fourth Indo-US Workshop on Mathematical Chemistry Held in Pune, Maharastra, India on 8-12 January 2005

DTIC Science & Technology

2005-01-12

Designing of less toxic to non target organophosphorus pesticide through multiple correlation analysis (MRA), a part of QSAR Rini Roy, Aditi Nag...of Organophosphorus Pesticide (OPs) in biological system and environment have implicated wide use of these types of pesticides in agriculture in...having minimal effect on any part of mammalian brain. In our study, we have dealt with the effects of phosphorothionate pesticides like methyl parathion

The Role of Attention in Information Processing Implications for the Design of Displays

DTIC Science & Technology

1989-12-01

processing system. Psychological Review, J, 214-255. Neisser , U . (1967). Cognitive Rsycholo&X. New York, NY: Appleton- Century-Crofts. Neisser , U . (1969...in the visual display is now an important part of a number of attention models. A related model suggested by Neisser (1967) is that successful...to filter attenuation theory have been proposed by Neisser (1967, 1969). According to Neisser’s theory, selective attention is an active process of

Resolving Phase Ambiguities in the Calibration of Redundant Interferometric Arrays: Implications for Array Design

DTIC Science & Technology

2016-03-04

summary of the linear algebra involved. As we have seen, the RSC process begins with the interferometric phase measurement β, which due to wrapping will...mentary Divisors) in Section 2 and the following defi- nition of the matrix determinant. This definition is given in many linear algebra texts (see...principle solve for a particular solution of this system by arbitrarily setting two object phases (whose spatial frequencies are not co- linear ) and one

Revisiting the JDL Model for Information Exploitation

DTIC Science & Technology

2013-07-01

High-Level Information Fusion Management and Systems Design, Artech House, Norwood, MA, 2012. [10] E. Blasch, D. A. Lambert, P. Valin , M. M. Kokar...Fusion – Fusion2012 Panel Discussion,” Int. Conf. on Info Fusion, 2012. [29] E. P. Blasch, P. Valin , A-L. Jousselme, et al., “Top Ten Trends in High...P. Valin , E. Bosse, M. Nilsson, J. Van Laere, et al., “Implication of Culture: User Roles in Information Fusion for Enhanced Situational

Characterization of pediatric wheelchair kinematics and wheelchair tiedown and occupant restraint system loading during rear impact.

PubMed

Fuhrman, Susan I; Karg, Patricia; Bertocci, Gina

2010-04-01

This study characterizes pediatric wheelchair kinematic responses and wheelchair tiedown and occupant restraint system (WTORS) loading during rear impact. It also examines the kinematic and loading effects of wheelchair headrest inclusion in rear impact. In two separate rear-impact test scenarios, identical WC19-compliant manual pediatric wheelchairs were tested using a seated Hybrid III 6-year-old anthropomorphic test device (ATD) to evaluate wheelchair kinematics and WTORS loading. Three wheelchairs included no headrests, and three were equipped with slightly modified wheelchair-mounted headrests. Surrogate WTORS properly secured the wheelchairs; three-point occupant restraints properly restrained the ATD. All tests used a 26km/h, 11g rear-impact test pulse. Headrest presence affected wheelchair kinematics and WTORS loading; headrest-equipped wheelchairs had greater mean seatback deflections, mean peak front and rear tiedown loads and decreased mean lap belt loads. Rear-impact tiedown loads differed from previously measured loads in frontal impact, with comparable tiedown load levels reversed in frontal and rear impacts. The front tiedowns in rear impact had the highest mean peak loads despite lower rear-impact severity. These outcomes have implications for wheelchair and tiedown design, highlighting the need for all four tiedowns to have an equally robust design, and have implications in the development of rear-impact wheelchair transportation safety standards. Copyright 2009 IPEM. Published by Elsevier Ltd. All rights reserved.

Carrageenan activates monocytes via type-specific binding with interleukin-8: an implication for design of immuno-active biomaterials.

PubMed

Chan, Weng-I; Zhang, Guangpan; Li, Xin; Leung, Chung-Hang; Ma, Dik-Lung; Dong, Lei; Wang, Chunming

2017-02-28

Polymers that can activate the immune system may become useful biomaterials tools, given that the mechanisms underlying their actions are well understood. Herein, we report a novel type of interaction between polymers and immune cells - in studying the influence of the three major types of carrageenan (CGN) polysaccharides on monocyte behaviour in vitro, we found only the λ-type induced monocyte adhesion and this action requires the presence of an adequate amount of serum. Further analyses indicated λ-CGN bound interleukin-8 (IL-8) in the serum and activated the cultured monocytes through an IL-8-dependent pathway. This is the first demonstration that a polymer, with a renowned immunostimulatory effect, activates the immune system via binding and harnessing the function of a specific cytokine in the microenvironment. This is a new mechanism underlying polymer-immunity interactions that may shed light on future design and application of biomaterials tools targeting the immune system for a wide variety of therapeutic applications.

Sense and nonsense of logic-level optical interconnect: reflections on an experiment

NASA Astrophysics Data System (ADS)

Van Campenhout, Jan M.; Brunfaut, Marnik; Meeus, Wim; Dambre, Joni; De Wilde, Michiel

2001-12-01

Centimeter-range high-density optical interconnect between chips is coming into reach with current optical interconnect technology. Many theoretical studies have identified several good reasons why to use such types of interconnect as a replacement of various layers of the traditional electronic interconnect hierarchy. However, the true feasibility and usefulness of optical interconnects can only be established by actually building and evaluating them in a real system setting. This contribution reports on our experience in using short-range high-density optical inter-chip interconnects. It is based on the design and construction of a fully functional optoelectronic demonstrator system. We discuss the rationale for building the demonstrator in the first place, the implications of using many low-level optical interconnections in electronic systems, and the degree to which our expectations have been fulfilled by the demonstrator. The detailed description of the architecture, design and implementation of the demonstrator is not presented here, but can be found elsewhere in this issue.

Advanced medical imaging protocol workflow-a flexible electronic solution to optimize process efficiency, care quality and patient safety in the National VA Enterprise.

PubMed

Medverd, Jonathan R; Cross, Nathan M; Font, Frank; Casertano, Andrew

2013-08-01

Radiologists routinely make decisions with only limited information when assigning protocol instructions for the performance of advanced medical imaging examinations. Opportunity exists to simultaneously improve the safety, quality and efficiency of this workflow through the application of an electronic solution leveraging health system resources to provide concise, tailored information and decision support in real-time. Such a system has been developed using an open source, open standards design for use within the Veterans Health Administration. The Radiology Protocol Tool Recorder (RAPTOR) project identified key process attributes as well as inherent weaknesses of paper processes and electronic emulators of paper processes to guide the development of its optimized electronic solution. The design provides a kernel that can be expanded to create an integrated radiology environment. RAPTOR has implications relevant to the greater health care community, and serves as a case model for modernization of legacy government health information systems.

Sharing Personal Reflections on Health Locally

NASA Astrophysics Data System (ADS)

Grimes, Andrea

Researchers are becoming increasingly interested in developing systems that help people live healthier lifestyles. Little attention has been paid, however, to how technology can address the significant health disparities in populations such as low-income African Americans. To address this research gap, I designed EatWell specifically for residents in low-income African American communities in Atlanta, GA. EatWell is a system for cell phones that lets people share how they have tried to eat healthfully with individuals in their local neighborhoods. In this chapter, I discuss the characteristics of the community that was created as people shared their personal stories and reflections in EatWell. Specifically, I describe the users themselves (the who), the context of use (the where), the kind of content people created (the what), and the way in which they interacted with the content (the how). Finally, I discuss the implications of designing health applications for people in local contexts, a class of systems that I call deeply local health applications.

The role of locally-designed organizational artifacts in supporting nurses’ work: an ethnographic study on the wards

PubMed

Talamo, Alessandra; Mellini, Barbara; Barbieri, Barbara

2017-01-01

This paper aims to describe how nurses' planning and coordination work is performed through the use of locally designed tools (i.e., diaries, planners, reminders, and organizers). These tools are investigated as the materialization of organizational work, thus offering a complementary perspective on nursing practice to that proposed by the professional mandate and supported by official artifacts in use. Ethnographic study. By analyzing locally designed artifacts, the rationale that enables nurses to make the flow of activities work is highlighted and explained. Evidence is provided by a description of how nurses' tacit knowledge is reified and embedded into objects produced by the nurses themselves. Implications for the design of digital systems supporting nursing practice are discussed. The analysis of these artifacts has allowed an understanding of practices used by the nurses to manage the workflow in the wards.

Josephson 4 K-bit cache memory design for a prototype signal processor. I - General overview

NASA Astrophysics Data System (ADS)

Henkels, W. H.; Geppert, L. M.; Kadlec, J.; Epperlein, P. W.; Beha, H.

1985-09-01

In the early stages of thg Josephson computer project conducted at an American computer company, it was recognized that a very fast cache memory was needed to complement Josephson logic. A subnanosecond access time memory was implemented experimentally on the basis of a 2.5-micron Pb-alloy technology. It was then decided to switch over to a Nb-base-electrode technology with the objective to alleviate problems with the long-term reliability and aging of Pb-based junctions. The present paper provides a general overview of the status of a 4 x 1 K-bit Josephson cache design employing a 2.5-micron Nb-edge-junction technology. Attention is given to the fabrication process and its implications, aspects of circuit design methodology, an overview of system environment and chip components, design changes and status, and various difficulties and uncertainties.

Designing attractive gamification features for collaborative storytelling websites.

PubMed

Hsu, Shang Hwa; Chang, Jen-Wei; Lee, Chun-Chia

2013-06-01

Gamification design is considered as the predictor of collaborative storytelling websites' success. Although aforementioned studies have mentioned a broad range of factors that may influence gamification, they neither depicted the actual design features nor relative attractiveness among them. This study aims to identify attractive gamification features for collaborative storytelling websites. We first constructed a hierarchical system structure of gamification design of collaborative storytelling websites and conducted a focus group interview with eighteen frequent users to identify 35gamification features. After that, this study determined the relative attractiveness of these gamification features by administrating an online survey to 6333 collaborative storytelling websites users. The results indicated that the top 10 most attractive gamification features could account for more than 50% of attractiveness among these 35 gamification features. The feature of unpredictable time pressure is important to website users, yet not revealed in previous relevant studies. Implications of the findings were discussed.

Management by consent in human-machine systems: when and why it breaks down.

PubMed

Olson, W A; Sarter, N B

2001-01-01

This study examined the effects of conflict type, time pressure, and display design on operators' ability to make informed decisions about proposed machine goals and actions in a management-by-consent context. A group of 30 B757 pilots were asked to fly eight descent scenarios while responding to a series of air traffic control clearances. Each scenario presented pilots with a different conflict that arose from either incompatible goals contained in the clearance or inappropriate implementation of the clearance by automated flight deck systems. Pilots were often unable to detect these conflicts, especially under time pressure, and thus failed to disallow or intervene with proposed machine actions. Detection performance was particularly poor for conflicts related to clearance implementation. These conflicts were most likely to be missed when automated systems did more than the pilot expected of them. Performance and verbal protocol data indicate that the observed difficulties can be explained by a combination of poor system feedback and pilots' difficulties with generating expectations of future system behavior. Our results are discussed in terms of their implications for the choice and implementation of automation management strategies in general and, more specifically, with respect to risks involved in envisioned forms of digital air-ground communication in the future aviation system. Actual or potential applications of this research include the design of future data link systems and procedures, as well as the design of future automated systems in any domain that rely on operator consent as a mechanism for human-machine coordination.

An Intervention in Literacy in Three Pacific Nations: Implications of a Context Specific Approach to Co-Design

ERIC Educational Resources Information Center

Jesson, Rebecca N.; Spratt, Rebecca

2017-01-01

In this paper, we consider the implications of a commitment to acknowledging the role of context within a research practice partnership. We outline the approach to doing so within a design-based research intervention with 42 schools across three Pacific Island countries to improve literacy learning and language development. In doing so, the paper…

A review of dynamic stability of repulsive-force maglev suspension systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cai, Y.; Rote, D.M.

1998-07-01

Vehicle dynamics and the need to satisfy ride quality requirements have long been recognized as crucial to the commercial success of passenger-carrying transportation systems. Design concepts for maglev systems are no exception. Early maglev investigators and designers were well aware of the importance of ride quality and took care to ensure that their designs would meet acceptable ride quality standards. In contrast, the dynamic stability of electrodynamic suspension (EDS) systems, which has obvious implications for system safety and cost as well as for ride quality, has not received nearly as much attention. Because of the well-known under-damped nature of EDSmore » suspension systems and the observation of instabilities in laboratory-scale model systems, it is prudent to develop a better understanding of vehicle stability characteristics. The work reported in this was undertaken with the intention of summarizing information that has been accumulated worldwide and that is relevant to dynamic stability of repulsive-force maglev suspension systems, assimilating that information, and gaining an understanding of the factors that influence that stability. Included in the paper is a discussion and comparison of results acquired from some representative tests of large-scale vehicles on linear test tracks, together with analytical and laboratory-scale investigations of stability and dynamics of EDS systems. This paper will also summarize the R and D activities at Argonne National Laboratory (ANL) since 1991 to study the nature of the forces that are operative in an EDS system and the dynamic stability of such systems.« less

Development and Demonstration of Active Noise Control Concepts

NASA Technical Reports Server (NTRS)

Kraft, R.; Hu, Z.; Sommerfeldt, S.; Walker, B.; Hersh, A.; Luo, H.; Spencer, M.; Hallman, D.; Mitchell, C.; Sutliff, D.

2000-01-01

This report details design methods for and feasibility of an Active Noise Control (ANC) system using flush-wall-mounted sensors and actuators to reduce turbofan engine rotor-stator interaction noise. ANC concepts capable of suppressing discrete-tone spinning modes containing several cut-on radial mode were identified, developed analytically, and evaluated. Separate ANC systems that suppressed at least three radial modes in a cylindrical inlet duct and three radial modes in an exhaust annulus were developed. These designs resulted in inlet duct and exhaust duct tests that were performed at NASA on the 4-ft ANC Fan in the NASA Glenn AAPL facility. Effective suppression of 2-BPF spinning mode m = 2 tone noise was achieved over a range of fan speeds 1800 to 2450 rpm, where up to 4 radials were present. In the inlet duct, up to 12 dB reduction was obtained for 3 radial modes, and up to 4 dB was obtained with 4 radial modes. In the exhaust duct, up to 15 dB PWL reduction was obtained with either two or three radial modes present. Thus, the ability to suppress multiple radial modes for tones in both the inlet and exhaust ducts has been successfully demonstrated. Implications of ANC system design requirements on installation and system integration issues for ANC systems capable of suppressing higher order radial mode content when applied to a 767 using twin CF6 engines were evaluated analytically. The analytical results indicated an ANC system must be part of an integrated design to be effective.

Crosswatch: a System for Providing Guidance to Visually Impaired Travelers at Traffic Intersections

PubMed Central

Coughlan, James M.; Shen, Huiying

2013-01-01

Purpose This paper describes recent progress on the “Crosswatch” project, a smartphone-based system developed for providing guidance to blind and visually impaired travelers at traffic intersections. Building on past work on Crosswatch functionality to help the user achieve proper alignment with the crosswalk and read the status of walk lights to know when it is time to cross, we outline the directions Crosswatch is now taking to help realize its potential for becoming a practical system: namely, augmenting computer vision with other information sources, including geographic information systems (GIS) and sensor data, and inferring the user's location much more precisely than is possible through GPS alone, to provide a much larger range of information about traffic intersections to the pedestrian. Design/methodology/approach The paper summarizes past progress on Crosswatch and describes details about the development of new Crosswatch functionalities. One such functionality, which is required for determination of the user's precise location, is studied in detail, including the design of a suitable user interface to support this functionality and preliminary tests of this interface with visually impaired volunteer subjects. Findings The results of the tests of the new Crosswatch functionality demonstrate that the functionality is feasible in that it is usable by visually impaired persons. Research limitations/implications While the tests that were conducted of the new Crosswatch functionality are preliminary, the results of the tests have suggested several possible improvements, to be explored in the future. Practical implications The results described in this paper suggest that the necessary technologies used by the Crosswatch system are rapidly maturing, implying that the system has an excellent chance of becoming practical in the near future. Originality/value The paper addresses an innovative solution to a key problem faced by blind and visually impaired travelers, which has the potential to greatly improve independent travel for these individuals. PMID:24353745

Plug-in hybrid electric vehicle LiFePO4 battery life implications of thermal management, driving conditions, and regional climate

NASA Astrophysics Data System (ADS)

Yuksel, Tugce; Litster, Shawn; Viswanathan, Venkatasubramanian; Michalek, Jeremy J.

2017-01-01

Battery degradation strongly depends on temperature, and many plug-in electric vehicle applications employ thermal management strategies to extend battery life. The effectiveness of thermal management depends on the design of the thermal management system as well as the battery chemistry, cell and pack design, vehicle system characteristics, and operating conditions. We model a plug-in hybrid electric vehicle with an air-cooled battery pack composed of cylindrical LiFePO4/graphite cells and simulate the effect of thermal management, driving conditions, regional climate, and vehicle system design on battery life. We estimate that in the absence of thermal management, aggressive driving can cut battery life by two thirds; a blended gas/electric-operation control strategy can quadruple battery life relative to an all-electric control strategy; larger battery packs can extend life by an order of magnitude relative to small packs used for all-electric operation; and batteries last 73-94% longer in mild-weather San Francisco than in hot Phoenix. Air cooling can increase battery life by a factor of 1.5-6, depending on regional climate and driving patterns. End of life criteria has a substantial effect on battery life estimates.

Implications for a Wireless, External Device System to Study Electrocorticography

PubMed Central

Rotermund, David; Pistor, Jonas; Hoeffmann, Janpeter; Schellenberg, Tim; Boll, Dmitriy; Tolstosheeva, Elena; Gauck, Dieter; Stemmann, Heiko; Peters-Drolshagen, Dagmar; Kreiter, Andreas Kurt; Schneider, Martin; Paul, Steffen; Lang, Walter; Pawelzik, Klaus Richard

2017-01-01

Implantable neuronal interfaces to the brain are an important keystone for future medical applications. However, entering this field of research is difficult since such an implant requires components from many different areas of technology. Since the complete avoidance of wires is important due to the risk of infections and other long-term problems, means for wirelessly transmitting data and energy are a necessity which adds to the requirements. In recent literature, many high-tech components for such implants are presented with remarkable properties. However, these components are typically not freely available for such a system. Every group needs to re-develop their own solution. This raises the question if it is possible to create a reusable design for an implant and its external base-station, such that it allows other groups to use it as a starting point. In this article, we try to answer this question by presenting a design based exclusively on commercial off-the-shelf components and studying the properties of the resulting system. Following this idea, we present a fully wireless neuronal implant for simultaneously measuring electrocorticography signals at 128 locations from the surface of the brain. All design files are available as open source. PMID:28375161

Artificial Gravity for Mars Missions: The Different Design and Development Options

NASA Technical Reports Server (NTRS)

Murbach, Marcus; Arno, Roger D.

2000-01-01

One of the major impediments to human Mars missions is the development of appropriate countermeasures for long term physiological response to the micro-gravity environment. A plethora of countermeasure approaches have been advanced from strictly pharmacological measures to large diameter rotating spacecraft that would simulate a 1-g environment (the latter being the most conservative from a human health perspective). The different approaches have significantly different implications not only on the overall system design of a Mars Mission Vehicle (MMV) but on the necessary earth-orbiting platform that would be required to qualify the particular countermeasure system. it is found that these different design options can be conveniently categorized in terms of the order of magnitude of the rotation diameter required (100's, 10's, 1's, 0 meters). From this, the different mass penalties associated with each category can be generally compared. The overall objective of the countermeasure system should be to maximize crew safety and comfort, minimize exercise protocol time (i.e., the time per day that each crew member would have to participate in the exercise/countermeasure), maximize countermeasure effectiveness, and minimize the associated system mass penalty of the Mars Mission Vehicle (in terms of fraction of IMLEO - Injected Mass in Low Earth Orbit).

Shielding and activation calculations around the reactor core for the MYRRHA ADS design

NASA Astrophysics Data System (ADS)

Ferrari, Anna; Mueller, Stefan; Konheiser, J.; Castelliti, D.; Sarotto, M.; Stankovskiy, A.

2017-09-01

In the frame of the FP7 European project MAXSIMA, an extensive simulation study has been done to assess the main shielding problems in view of the construction of the MYRRHA accelerator-driven system at SCK·CEN in Mol (Belgium). An innovative method based on the combined use of the two state-of-the-art Monte Carlo codes MCNPX and FLUKA has been used, with the goal to characterize complex, realistic neutron fields around the core barrel, to be used as source terms in detailed analyses of the radiation fields due to the system in operation, and of the coupled residual radiation. The main results of the shielding analysis are presented, as well as the construction of an activation database of all the key structural materials. The results evidenced a powerful way to analyse the shielding and activation problems, with direct and clear implications on the design solutions.

Ensuring Patient Safety in Care Transitions: An Empirical Evaluation of a Handoff Intervention Tool

PubMed Central

Abraham, Joanna; Kannampallil, Thomas; Patel, Bela; Almoosa, Khalid; Patel, Vimla L.

2012-01-01

Successful handoffs ensure smooth, efficient and safe patient care transitions. Tools and systems designed for standardization of clinician handoffs often focuses on ensuring the communication activity during transitions, with limited support for preparatory activities such as information seeking and organization. We designed and evaluated a Handoff Intervention Tool (HAND-IT) based on a checklist-inspired, body system format allowing structured information organization, and a problem-case narrative format allowing temporal description of patient care events. Based on a pre-post prospective study using a multi-method analysis we evaluated the effectiveness of HAND-IT as a documentation tool. We found that the use of HAND-IT led to fewer transition breakdowns, greater tool resilience, and likely led to better learning outcomes for less-experienced clinicians when compared to the current tool. We discuss the implications of our results for improving patient safety with a continuity of care-based approach. PMID:23304268

Plant photomorphogenesis and canopy growth

NASA Technical Reports Server (NTRS)

Ballare, Carlos L.; Scopel, Ana L.

1994-01-01

An important motivation for studying photomorphogenesis is to understand the relationships among plant photophysiology in canopies, canopy productivity, and agronomic yield. This understanding is essential to optimize lighting systems used for plant farming in controlled environments (CE) and for the design of genetically engineered crop strains with altered photoresponses. This article provides an overview of some basic principles of plant photomorphogenesis in canopies and discusses their implications for (1) scaling up information on plant photophysiology from individual plants in CE to whole canopies in the field, and (2) designing lighting conditions to increase plant productivity in CE used for agronomic purposes (e.g. space farming in CE Life Support Systems). We concentrate on the visible (lambda between 400 and 700 nm) and far-infrared (FR; lambda greater than 700 nm) spectral regions, since the ultraviolet (UV; 280 to 400 nm) is covered by other authors in this volume.

Plant photomorphogenesis and canopy growth

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ballare, C.L.; Scopel, A.L.

1994-12-31

An important motivation for studying photomorphogenesis is to understand the relationships among plant photophysiology in canopies, canopy productivity, and agronomic yield. This understanding is essential to optimize lighting systems used for plant farming in controlled environments (CE) and for the design of genetically engineered crop strains with altered photoresponses. This article provides an overview of some basic principles of plant photomorphogenesis in canopies and discusses their implications for (1) scaling up information on plant photophysiology from individual plants in CE to whole canopies in the field, and (2), designing lighting conditions to increase plant productivity in CE used for agronomicmore » purposes [e.g. space farming in CE Life-Support-Systems]. We concentrate on the visible ({lambda} between 400 and 700 nm) and far red (FR; {lambda} > 700 nm) spectral regions, since the ultraviolet (UV; 280 to 400 nm) is covered by other authors in this volume.« less

Biological Implications of Dynamical Phases in Non-equilibrium Networks

NASA Astrophysics Data System (ADS)

Murugan, Arvind; Vaikuntanathan, Suriyanarayanan

2016-03-01

Biology achieves novel functions like error correction, ultra-sensitivity and accurate concentration measurement at the expense of free energy through Maxwell Demon-like mechanisms. The design principles and free energy trade-offs have been studied for a variety of such mechanisms. In this review, we emphasize a perspective based on dynamical phases that can explain commonalities shared by these mechanisms. Dynamical phases are defined by typical trajectories executed by non-equilibrium systems in the space of internal states. We find that coexistence of dynamical phases can have dramatic consequences for function vs free energy cost trade-offs. Dynamical phases can also provide an intuitive picture of the design principles behind such biological Maxwell Demons.

The role of privacy protection in healthcare information systems adoption.

PubMed

Hsu, Chien-Lung; Lee, Ming-Ren; Su, Chien-Hui

2013-10-01

Privacy protection is an important issue and challenge in healthcare information systems (HISs). Recently, some privacy-enhanced HISs are proposed. Users' privacy perception, intention, and attitude might affect the adoption of such systems. This paper aims to propose a privacy-enhanced HIS framework and investigate the role of privacy protection in HISs adoption. In the proposed framework, privacy protection, access control, and secure transmission modules are designed to enhance the privacy protection of a HIS. An experimental privacy-enhanced HIS is also implemented. Furthermore, we proposed a research model extending the unified theory of acceptance and use of technology by considering perceived security and information security literacy and then investigate user adoption of a privacy-enhanced HIS. The experimental results and analyses showed that user adoption of a privacy-enhanced HIS is directly affected by social influence, performance expectancy, facilitating conditions, and perceived security. Perceived security has a mediating effect between information security literacy and user adoption. This study proposes several implications for research and practice to improve designing, development, and promotion of a good healthcare information system with privacy protection.

A Systematic Review of fMRI Reward Paradigms in Adolescents versus Adults: The Impact of Task Design and Implications for Understanding Neurodevelopment

PubMed Central

Richards, Jessica M.; Plate, Rista C.; Ernst, Monique

2013-01-01

The neural systems underlying reward-related behaviors across development have recently generated a great amount of interest. Yet, the neurodevelopmental literature on reward processing is marked by inconsistencies due to the heterogeneity of the reward paradigms used, the complexity of the behaviors being studied, and the developing brain itself as a moving target. The present review will examine task design as one source of variability across findings by compiling this literature along three dimensions: (1) task structures, (2) cognitive processes, and (3) neural systems. We start with the presentation of a heuristic neural systems model, the Triadic Model, as a way to provide a theoretical framework for the neuroscience research on motivated behaviors. We then discuss the principles guiding reward task development. Finally, we review the extant developmental neuroimaging literature on reward-related processing, organized by reward task type. We hope that this approach will help to clarify the literature on the functional neurodevelopment of reward-related neural systems, and to identify the role of the experimental parameters that significantly influence these findings. PMID:23518270

Engineering the curriculum: Towards an adaptive curriculum

NASA Astrophysics Data System (ADS)

Johns-Boast, Lynette Frances

The curriculum is one of the most important artefacts produced by higher education institutions, yet it is one of the least studied. Additionally, little is known about the decision-making of academics when designing and developing their curricula, nor how they make use of them. This research investigates how 22 Australian higher education engineering, software engineering, computer science, and information systems academics conceive of curriculum, what approaches they take when designing, and developing course and program curricula, and what use they make of the curriculum. It also considers the implications of these conceptions and behaviour upon their curricula. Data were collected through a series of one-to-one, in-depth, qualitative interviews as well as small focus group sessions and were analysed following Charmaz’ (2006) approach to grounded theory. In this thesis, I argue that the development of curricula for new higher degree programs and courses and / or the updating and innovating of an existing curriculum is a design problem. I also argue that curriculum is a complex adaptive system. Surrounding the design and development of a curriculum is a process of design that leads to the creation of a designed object - the official-curriculum. The official-curriculum provides the guiding principles for its implementation, which involves the design and development of the curriculum-in-use, its delivery, and evaluation. Data show that while the participants conceive of curriculum as a problem of design involving a design process leading to the development of the official-curriculum, surprisingly, their behaviour does not match their conceptions. Over a very short period, their behaviour leads to a process I have called curriculum drift where the official-curriculum and the curriculum-in-use drift away from each other causing the curriculum to lose its integrity. Curricular integrity is characterised through the attributes of alignment, coherence, and cohesiveness. Without integrity, a curriculum is unlikely to be able to deliver all its required outcomes. Utilising the concepts of system dynamics and systems thinking I propose that not only is the curriculum a complex adaptive system, it is a multi-dimensional object. Adopting this notion facilitates possible interventions that may be used to monitor the curriculum and to moderate the effects of curriculum drift. I argue that using the articulated purpose of the curriculum to determine the desired outcomes of that curriculum will enhance curricular alignment, leading to improved student learning and outcomes. Furthermore, perceiving the curriculum as a multi-dimensional object reinforces the proposition that aligning the purpose and desired outcomes of each course with those of the program will achieve improved desired outcomes from the program as a whole. The original contributions to knowledge arising from this research are curriculum drift, an enhanced approach to the curricular alignment, and a multi-dimensional view of curriculum. Perhaps the most important implication of this research, is insight into how we might incorporate curriculum drift into curriculum review models. Successful incorporation has the potential to deliver increased quality of educational outcomes by enabling innovation whilst maintaining the integrity of the curriculum.

How to Study Chronic Diseases-Implications of the Convention on the Rights of Persons with Disabilities for Research Designs.

PubMed

von Peter, Sebastian; Bieler, Patrick

2017-01-01

The Convention on the Rights of Persons with Disabilities (CRPD) has been received considerable attention internationally. The Convention's main arguments are conceptually analyzed. Implications for the development of research designs are elaborated upon. The Convention entails both a human rights and a sociopolitical dimension. Advancing a relational notion of disability, it enters a rather foreign terrain to medical sciences. Research designs have to be changed accordingly. Research designs in accordance with the CRPD should employ and further develop context-sensitive research strategies and interdisciplinary collaboration. Complex designs that allow for a relational analysis of personalized effects have to be established and evaluated, thereby systematically integrating qualitative methods.

A Markovian state-space framework for integrating flexibility into space system design decisions

NASA Astrophysics Data System (ADS)

Lafleur, Jarret M.

The past decades have seen the state of the art in aerospace system design progress from a scope of simple optimization to one including robustness, with the objective of permitting a single system to perform well even in off-nominal future environments. Integrating flexibility, or the capability to easily modify a system after it has been fielded in response to changing environments, into system design represents a further step forward. One challenge in accomplishing this rests in that the decision-maker must consider not only the present system design decision, but also sequential future design and operation decisions. Despite extensive interest in the topic, the state of the art in designing flexibility into aerospace systems, and particularly space systems, tends to be limited to analyses that are qualitative, deterministic, single-objective, and/or limited to consider a single future time period. To address these gaps, this thesis develops a stochastic, multi-objective, and multi-period framework for integrating flexibility into space system design decisions. Central to the framework are five steps. First, system configuration options are identified and costs of switching from one configuration to another are compiled into a cost transition matrix. Second, probabilities that demand on the system will transition from one mission to another are compiled into a mission demand Markov chain. Third, one performance matrix for each design objective is populated to describe how well the identified system configurations perform in each of the identified mission demand environments. The fourth step employs multi-period decision analysis techniques, including Markov decision processes from the field of operations research, to find efficient paths and policies a decision-maker may follow. The final step examines the implications of these paths and policies for the primary goal of informing initial system selection. Overall, this thesis unifies state-centric concepts of flexibility from economics and engineering literature with sequential decision-making techniques from operations research. The end objective of this thesis’ framework and its supporting tools is to enable selection of the next-generation space systems today, tailored to decision-maker budget and performance preferences, that will be best able to adapt and perform in a future of changing environments and requirements. Following extensive theoretical development, the framework and its steps are applied to space system planning problems of (1) DARPA-motivated multiple- or distributed-payload satellite selection and (2) NASA human space exploration architecture selection.

Quorum-Sensing Signal-Response Systems in Gram-Negative Bacteria

PubMed Central

Papenfort, Kai; Bassler, Bonnie

2016-01-01

Abstract / Preface Bacteria use quorum sensing to orchestrate gene expression programmes that underlie collective behaviours. Quorum sensing relies on the production, release, detection and group-level response to extracellular signalling molecules, which are called autoinducers. Recent work has discovered new autoinducers in Gram-negative bacteria, shown how these molecules are recognized by cognate receptors, revealed new regulatory components that are embedded in canonical signalling circuits and identified novel regulatory network designs. In this Review we examine how, together, these features of quorum sensing signal–response systems combine to control collective behaviours in Gram-negative bacteria and we discuss the implications for host–microbial associations and antibacterial therapy. PMID:27510864

SETS. Set Equation Transformation System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Worrell, R.B.

1992-01-13

SETS is used for symbolic manipulation of Boolean equations, particularly the reduction of equations by the application of Boolean identities. It is a flexible and efficient tool for performing probabilistic risk analysis (PRA), vital area analysis, and common cause analysis. The equation manipulation capabilities of SETS can also be used to analyze noncoherent fault trees and determine prime implicants of Boolean functions, to verify circuit design implementation, to determine minimum cost fire protection requirements for nuclear reactor plants, to obtain solutions to combinatorial optimization problems with Boolean constraints, and to determine the susceptibility of a facility to unauthorized access throughmore » nullification of sensors in its protection system.« less

Enterprise Architecture Planning in developing A planning Information System: a Case Study of Semarang State University

NASA Astrophysics Data System (ADS)

Budiman, Kholiq; Prahasto, Toni; Kusumawardhani, Amie

2018-02-01

This research has applied an integrated design and development of planning information system, which is been designed using Enterprise Architecture Planning. Frequent discrepancy between planning and realization of the budget that has been made, resulted in ineffective planning, is one of the reason for doing this research. The design using EAP aims to keep development aligned and in line with the strategic direction of the organization. In the practice, EAP is carried out in several stages of the planning initiation, identification and definition of business functions, proceeded with architectural design and EA implementation plan that has been built. In addition to the design of the Enterprise Architecture, this research carried out the implementation, and was tested by several methods of black box and white box. Black box testing method is used to test the fundamental aspects of the software, tested by two kinds of testing, first is using User Acceptance Testing and the second is using software functionality testing. White box testing method is used to test the effectiveness of the code in the software, tested using unit testing. Tests conducted using white box and black box on the integrated planning information system, is declared successful. Success in the software testing can not be ascertained if the software built has not shown any distinction from prior circumstance to the development of this integrated planning information system. For ensuring the success of this system implementation, the authors test consistency between the planning of data and the realization of prior-use of the information system, until after-use information system. This consistency test is done by reducing the time data of the planning and realization time. From the tabulated data, the planning information system that has been built reduces the difference between the planning time and the realization time, in which indicates that the planning information system can motivate the planner unit in realizing the budget that has been designed. It also proves that the value chain of the information planning system has brought implications for budget realization.

The nature of arm movement in children with cerebral palsy when using computer-generated exercise games.

PubMed

Weightman, Andrew; Preston, Nick; Levesley, Martin; Bhakta, Bipin; Holt, Raymond; Mon-Williams, Mark

2014-05-01

To compare upper limb kinematics of children with spastic cerebral palsy (CP) using a passive rehabilitation joystick with those of adults and able-bodied children, to better understand the design requirements of computer-based rehabilitation devices. A blocked comparative study involving seven children with spastic CP, nine able-bodied adults and nine able-bodied children, using a joystick system to play a computer game whilst the kinematics of their upper limb were recorded. The translational kinematics of the joystick's end point and the participant's shoulder movement (protraction/retraction) and elbow rotational kinematics (flexion/extension) were analysed for each group. Children with spastic CP matched their able-bodied peers in the time taken to complete the computer task, but this was due to a failure to adhere to the task instructions of travelling along a prescribed straight line when moving between targets. The spastic CP group took longer to initiate the first movement, which showed jerkier trajectories and demonstrated qualitatively different movement patterns when using the joystick, with shoulder movements that were significantly of greater magnitude than the able-bodied participants. Children with spastic CP generate large shoulder and hence trunk movements when using a joystick to undertake computer-generated arm exercises. This finding has implications for the development and use of assistive technologies to encourage exercise and the instructions given to users of such systems. A kinematic analysis of upper limb function of children with CP when using joystick devices is presented. Children with CP may use upper body movements to compensate for limitations in voluntary shoulder and elbow movements when undertaking computer games designed to encourage the practice of arm movement. The design of rehabilitative computer exercise systems should consider movement of the torso/shoulder as it may have implications for the quality of therapy in the rehabilitation of the upper limb in children with CP.

Modeling Piezoelectric Stack Actuators for Control of Micromanipulation

NASA Technical Reports Server (NTRS)

Goldfarb, Michael; Celanovic, Nikola

1997-01-01

A nonlinear lumped-parameter model of a piezoelectric stack actuator has been developed to describe actuator behavior for purposes of control system analysis and design, and, in particular, for microrobotic applications requiring accurate position and/or force control. In formulating this model, the authors propose a generalized Maxwell resistive capacitor as a lumped-parameter causal representation of rate-independent hysteresis. Model formulation is validated by comparing results of numerical simulations to experimental data. Validation is followed by a discussion of model implications for purposes of actuator control.

In silico cancer modeling: is it ready for primetime?

PubMed Central

Deisboeck, Thomas S; Zhang, Le; Yoon, Jeongah; Costa, Jose

2011-01-01

SUMMARY At the dawn of the era of personalized, systems-driven medicine, computational or in silico modeling and the simulation of disease processes is becoming increasingly important for hypothesis generation and data integration in both experiment and clinics alike. Arguably, this is nowhere more visible than in oncology. To illustrate the field’s vast potential as well as its current limitations we briefly review selected works on modeling malignant brain tumors. Implications for clinical practice, including trial design and outcome prediction are also discussed. PMID:18852721

On bilinearity of Manson-Coffin low-cycle-fatigue relationship

NASA Technical Reports Server (NTRS)

Radhakrishnan, V. M.

1992-01-01

Some alloy systems, such as aluminum-lithium alloys and dual-phase steels, have been found to show a bilinear Manson-Coffin low-cycle-fatigue relationship. This paper shows that such bilinear behavior is related to the cyclic stress-strain curve. A bilinear cyclic stress-strain curve is a likely indication of a bilinear Manson-Coffin relationship. It is shown that materials other than aluminum-lithium alloys and dual-phase steels also may exhibit bilinear Manson-Coffin behavior. Implications for design are discussed.

Progress Towards Understanding Fan Inlet Implications of Top-Mounted Propulsion

NASA Technical Reports Server (NTRS)

Friedlander, David

2017-01-01

Computational fluid dynamic (CFD) simulations were performed on an N+2 commercial supersonic transport aircraft design that featured top-mounted propulsion. The simulations were run at take-off conditions at both 0 degrees and 8 degrees angle of attack. The results showed little separation in around the inlets with inlet performance on par with an under-the-wing configuration. The next step will be to take these results and determine the acoustic impact of the top-mounted propulsion system.

Fluoride-selective optical sensor based on the dipyrrolyl-tetrathiafulvalene chromophore.

PubMed

Rivadehi, Shadi; Reid, Ellen F; Hogan, Conor F; Bhosale, Sheshanath V; Langford, Steven J

2012-01-28

A chemosensor bearing dipyrrolyl motifs as recognition sites and a tetrathiafulvalene redox tag has been evaluated as an optical and redox sensor for a series of anions (F(-), Cl(-), Br(-), HSO(4)(-), CH(3)COO(-), and H(2)PO(4)(-)) in DCM solution. The receptor shows specific optical signaling for fluoride but little electrochemical effect in solution. The solid-state performance of the sensor leads to measurable changes in water. Design implications towards better systems based on these results and other examples are discussed.

Child neurology residency: system implications of new training models.

PubMed

Heiser, Karen

2012-02-01

From limitations on residents' duty hours, to ways in which outcomes are measured, changes to graduate medical education are sweeping the nation. In this issue of the journal, Gilbert and Greenwood present thoughtful, if somewhat disparate, opinions on ways to improve the educational experience of child neurology trainees. As the Designated Institutional Officer of a large children's hospital, I have focused my commentary on "the big picture." That is, what systemwide impact can changes in child neurology trainees' education have.

Employee Engagement and a Culture of Safety in the Intensive Care Unit.

PubMed

Collier, Susan L; Fitzpatrick, Joyce J; Siedlecki, Sandra L; Dolansky, Mary A

2016-01-01

A descriptive, retrospective design was used to explore the relationship between employee engagement and culture of safety in ICUs within a large Midwestern healthcare system. Results demonstrated a strong positive relationship between total engagement score and total patient safety score (r = 0.645, P < .01) and positive relationships between total engagement score and the 12 safety culture dimensions. These findings have implications for improving managerial strategies relative to employee engagement that may ultimately impact perceptions of a safety culture.

IPCS implications for future supersonic transport aircraft

NASA Technical Reports Server (NTRS)

Billig, L. O.; Kniat, J.; Schmidt, R. D.

1976-01-01

The Integrated Propulsion Control System (IPCS) demonstrates control of an entire supersonic propulsion module - inlet, engine afterburner, and nozzle - with an HDC 601 digital computer. The program encompasses the design, build, qualification, and flight testing of control modes, software, and hardware. The flight test vehicle is an F-111E airplane. The L.H. inlet and engine will be operated under control of a digital computer mounted in the weapons bay. A general description and the current status of the IPCS program are given.

Preliminary results on ocean dynamics from Skylab and their implications for future spacecraft

NASA Technical Reports Server (NTRS)

Hayes, J.; Pierson, W. J.; Cardone, V. J.

1975-01-01

The instrument aboard Skylab designated S193 - a combined passive and active microwave radar system acting as a radiometer, scatterometer, and altimeter - is used to measure the surface vector wind speeds in the planetary boundary layer over the oceans. Preliminary results corroborate the hypothesis that sea surface winds in the planetary boundary layer can be determined from satellite data. Future spacecraft plans for measuring a geoid with an accuracy up to 10 cm are discussed.

From managed care to consumer health insurance: the fall and rise of Aetna.

PubMed

Robinson, James C

2004-01-01

This paper documents Aetna's fall as the nation's largest managed care plan and its subsequent reemergence as a smaller but more profitable multiproduct insurer. The paper emphasizes the transformation in corporate goals, product design, organizational structure, information technology, product mix, premiums, cash flow, net income, and share prices. Disciplined underwriting and pricing have restored the firm to profitability and set the foundation for new growth. The implications for the health care system as a whole are less unambiguously positive.

Data System Implications Derived from User Application Requirements for Satellite Data

NASA Technical Reports Server (NTRS)

Neiers, J.

1979-01-01

An investigation of the data system needs as driven by users of space acquired Earth observation data is documented. Two major categories of users, operational and research, are identified. Limiting data acquisition alleviates some of the delays in processing thus improving timeliness of the delivered product. Trade offs occur between timeliness and data distribution costs, and between data storage and reprocessing. The complexity of the data system requirements to apply space data to users' needs is such that no single analysis suffices to design and implement the optimum system. A series of iterations is required with analyses of the salient problems in a general way, followed by a limited implementation of benefit to some users with a continual upgrade in system capacity, functions, and applications served. The resulting most important requirement for the data system is flexibility to accommodate changing requirements as the system is implemented.

Structure and mechanical implications of the pectoral fin skeleton in the Longnose Skate (Chondrichthyes, Batoidea).

PubMed

Huang, Wei; Hongjamrassilp, Watcharapong; Jung, Jae-Young; Hastings, Philip A; Lubarda, Vlado A; McKittrick, Joanna

2017-03-15

Animal propulsion systems are believed to show high energy and mechanical efficiency in assisting movement compared to artificial designs. As an example, batoid fishes have very light cartilaginous skeletons that facilitate their elegant swimming via enlarged wing-like pectoral fins. The aim of this work is to illustrate the hierarchical structure of the pectoral fin of a representative batoid, the Longnose Skate (Raja rhina), and explain the mechanical implications of its structural design. At the macro level, the pectoral fins are comprised of radially oriented fin rays, formed by staggered mineralized skeletal elements stacked end-to-end. At the micro level, the midsection of each radial element is composed of three mineralized components, which consist of discrete segments (tesserae) that are mineralized cartilage and embedded in unmineralized cartilage. The radial elements are wrapped with aligned, unmineralized collagen fibers. This is the first report of the detailed structure of the ray elements, including the observation of a 3-chain mineralized tesserae. Structural analyses demonstrate that this configuration enhances stiffness in multiple directions. A two-dimensional numerical model based on the morphological analysis demonstrated that the tessera structure helps distributing shear, tensile and compressive stress more ideally, which can better support both lift and thrust forces when swimming without losing flexibility. Batoid fishes have very light cartilaginous skeletons that facilitate their elegant swimming by applying their enlarged wing-like pectoral fins. Previous studies have shown structural features and mechanical properties of the mineralized cartilage skeleton in various batoid fishes. However, the details of the pectoral fin structure at different length scales, as well as the relationship between the mechanical properties and structural design remains unknown. The present work illustrates the hierarchical structure of the pectoral fin of the Longnose Skate (a representative batoid fish) and verifies the materials configuration and structural design increases the stiffness of fin skeleton without a loss in flexibility. These results have implications for the design of strong but flexible materials and bio-inspired autonomous underwater vehicles (AUVs). Copyright © 2017 Acta Materialia Inc. All rights reserved.

The experience of living with stroke and using technology: opportunities to engage and co-design with end users.

PubMed

Nasr, Nasrin; Leon, Beatriz; Mountain, Gail; Nijenhuis, Sharon M; Prange, Gerdienke; Sale, Patrizio; Amirabdollahian, Farshid

2016-11-01

We drew on an interdisciplinary research design to examine stroke survivors' experiences of living with stroke and with technology in order to provide technology developers with insight into values, thoughts and feelings of the potential users of a to-be-designed robotic technology for home-based rehabilitation of the hand and wrist. Ten stroke survivors and their family carers were purposefully selected. On the first home visit, they were introduced to cultural probe. On the second visit, the content of the probe packs were used as prompt to conduct one-to-one interviews with them. The data generated was analysed using thematic analysis. A third home visit was conducted to evaluate the early prototype. User requirements were categorised into their network of relationships, their attitude towards technology, their skills, their goals and motivations. The user requirements were used to envision the requirements of the system including providing feedback on performance, motivational aspects and usability of the system. Participants' views on the system requirements were obtained during a participatory evaluation. This study showed that prior to the development of technology, it is important to engage with potential users to identify user requirements and subsequently envision system requirements based on users' views. Implications for Rehabilitation An understanding of how stroke survivors make sense of their experiences of living with stroke is needed to design home-based rehabilitation technologies. Linking stroke survivors' goals, motivations, behaviour, feelings and attitude to user requirements prior to technology development has a significant impact on improving the design.

A usability evaluation of four commercial dental computer-based patient record systems

PubMed Central

Thyvalikakath, Thankam P.; Monaco, Valerie; Thambuganipalle, Hima Bindu; Schleyer, Titus

2008-01-01

Background The usability of dental computer-based patient record (CPR) systems has not been studied, despite early evidence that poor usability is a problem for dental CPR system users at multiple levels. Methods The authors conducted formal usability tests of four dental CPR systems by using a purposive sample of four groups of five novice users. The authors measured task outcomes (correctly completed, incorrectly completed and incomplete) in each CPR system while the participants performed nine clinical documentation tasks, as well as the number of usability problems identified in each CPR system and their potential relationship to task outcomes. The authors reviewed the software application design aspects responsible for these usability problems. Results The range for correctly completed tasks was 16 to 64 percent, for incorrectly completed tasks 18 to 38 percent and for incomplete tasks 9 to 47 percent. The authors identified 286 usability problems. The main types were three unsuccessful attempts, negative affect and task incorrectly completed. They also identified six problematic interface and interaction designs that led to usability problems. Conclusion The four dental CPR systems studied have significant usability problems for novice users, resulting in a steep learning curve and potentially reduced system adoption. Clinical Implications The significant number of data entry errors raises concerns about the quality of documentation in clinical practice. PMID:19047669

I want what you've got: Cross platform portabiity and human-robot interaction assessment.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Julie L. Marble, Ph.D.*.; Douglas A. Few; David J. Bruemmer

2005-08-01

Human-robot interaction is a subtle, yet critical aspect of design that must be assessed during the development of both the human-robot interface and robot behaviors if the human-robot team is to effectively meet the complexities of the task environment. Testing not only ensures that the system can successfully achieve the tasks for which it was designed, but more importantly, usability testing allows the designers to understand how humans and robots can, will, and should work together to optimize workload distribution. A lack of human-centered robot interface design, the rigidity of sensor configuration, and the platform-specific nature of research robot developmentmore » environments are a few factors preventing robotic solutions from reaching functional utility in real word environments. Often the difficult engineering challenge of implementing adroit reactive behavior, reliable communication, trustworthy autonomy that combines with system transparency and usable interfaces is overlooked in favor of other research aims. The result is that many robotic systems never reach a level of functional utility necessary even to evaluate the efficacy of the basic system, much less result in a system that can be used in a critical, real-world environment. Further, because control architectures and interfaces are often platform specific, it is difficult or even impossible to make usability comparisons between them. This paper discusses the challenges inherent to the conduct of human factors testing of variable autonomy control architectures and across platforms within a complex, real-world environment. It discusses the need to compare behaviors, architectures, and interfaces within a structured environment that contains challenging real-world tasks, and the implications for system acceptance and trust of autonomous robotic systems for how humans and robots interact in true interactive teams.« less

Interconnectedness and interdependencies of critical infrastructures in the US economy: Implications for resilience

NASA Astrophysics Data System (ADS)

Chopra, Shauhrat S.; Khanna, Vikas

2015-10-01

Natural disasters in 2011 yielded close to 55 billion in economic damages alone in the United States (US), which highlights the need to reduce impacts of such disasters or other deliberate attacks. The US Department of Homeland Security (DHS) identifies a list of 16 Critical Infrastructure Sectors (CIS) whose incapacity due to disruptions would have a debilitating impact on the nation's economy. The goal of this work is to understand the implications of interdependencies among CIS on the resilience of the US economic system as a whole. We develop a framework that combines the empirical economic input-output (EIO) model with graph theory based techniques for understanding interdependencies, interconnectedness and resilience in the US economic system. By representing the US economy as a network, we are able to analyze its topology by separately looking at its unweighted and weighted forms. Topological analysis of the US EIO network suggests that it exhibits small world properties for the unweighted case, and in the weighted case, the throughput of industry sectors follows a power-law with an exponential cutoff. Implications of these topological properties are discussed in the paper. We also simulate hypothetical disruptions on CIS in order to identify industrial sectors that experience the largest economic impacts, and to quantify systemic vulnerability in economic terms. In addition, insights from community detection and hypothetical disruption scenarios help assess vulnerability of individual industrial communities to disruptions on individual CIS. These methodologies also provide insights regarding the extent of coupling between each CIS in the US EIO network. Based on our analysis, we observe that excessive interconnectedness and interdependencies of CIS results in high systemic vulnerability. This information can guide policymakers to design policies that improve resilience of economic networks, and evaluate policies that might indirectly increase coupling between CIS.

Identification of Low Order Equivalent System Models From Flight Test Data

NASA Technical Reports Server (NTRS)

Morelli, Eugene A.

2000-01-01

Identification of low order equivalent system dynamic models from flight test data was studied. Inputs were pilot control deflections, and outputs were aircraft responses, so the models characterized the total aircraft response including bare airframe and flight control system. Theoretical investigations were conducted and related to results found in the literature. Low order equivalent system modeling techniques using output error and equation error parameter estimation in the frequency domain were developed and validated on simulation data. It was found that some common difficulties encountered in identifying closed loop low order equivalent system models from flight test data could be overcome using the developed techniques. Implications for data requirements and experiment design were discussed. The developed methods were demonstrated using realistic simulation cases, then applied to closed loop flight test data from the NASA F-18 High Alpha Research Vehicle.

Role of the limbic system in dependence on drugs.

PubMed

Rodríguez de Fonseca, F; Navarro, M

1998-08-01

The limbic system is a group of structurally and functionally related areas of the brain that provides the anatomical substrate for emotions and motivated behaviour, including the circuitry for the stress response and reward-related events. This system is strongly implicated in drug abuse from the pleasure and/or positive side associated with acute exposure to the dysphoria and craving associated with withdrawal. The contribution of the main cortical and subcortical elements of the limbic system to drug dependence is briefly reviewed in the present work with a focus on the role of the extended amygdala and its connections as well as on the peripheral feedback signals mediated by adrenal glucocorticoids. The elucidation of the neuroadaptive responses of the limbic system to chronic drug exposure will undoubtedly help to design rational strategies for the treatment of addiction.

Engineering the LISA Project: Systems Engineering Challenges

NASA Technical Reports Server (NTRS)

Evans, Jordan P.

2006-01-01

The Laser Interferometer Space Antenna (LISA) is a joint NASA/ESA mission to detect and measure gravitational waves with periods from 1 s to 10000 s. The systems engineering challenges of developing a giant interferometer, 5 million kilometers on a side, an: numerous. Some of the key challenges are presented in this paper. The organizational challenges imposed by sharing the engineering function between three centers (ESA ESTEC, NASA GSFC, and JPL) across nine time zones are addressed. The issues and approaches to allocation of the acceleration noise and measurement sensitivity budget terms across a traditionally decomposed system are discussed. Additionally, using LISA to detect gravitational waves for the first time presents significant data analysis challenges, many of which drive the project system design. The approach to understanding the implications of science data analysis on the system is also addressed.

Transforming Education to Strengthen Health Systems in the Sultanate of Oman

PubMed Central

White, Gillian

2012-01-01

Conspicuous gaps demonstrate a collective global failure in the world’s health systems as they struggle to manage complex and expensive demands. The Lancet Commission recently took a global interdisciplinary perspective and systematic approach to consider alliances between education for health professionals and health systems in order to address these problems. They concluded that positive outcomes require new instructional and institutional designs. Findings from the Lancet Commission have implications for the development of health professional education in Oman, particularly with regard to the call for integrative and transformative education for the next generation of health professionals. Education in the Omani health sector must keep up with increasing challenges in both the health and education sectors. PMID:23275838

Intuitive Cognition and Models of Human-Automation Interaction.

PubMed

Patterson, Robert Earl

2017-02-01

The aim of this study was to provide an analysis of the implications of the dominance of intuitive cognition in human reasoning and decision making for conceptualizing models and taxonomies of human-automation interaction, focusing on the Parasuraman et al. model and taxonomy. Knowledge about how humans reason and make decisions, which has been shown to be largely intuitive, has implications for the design of future human-machine systems. One hundred twenty articles and books cited in other works as well as those obtained from an Internet search were reviewed. Works were deemed eligible if they were published within the past 50 years and common to a given literature. Analysis shows that intuitive cognition dominates human reasoning and decision making in all situations examined. The implications of the dominance of intuitive cognition for the Parasuraman et al. model and taxonomy are discussed. A taxonomy of human-automation interaction that incorporates intuitive cognition is suggested. Understanding the ways in which human reasoning and decision making is intuitive can provide insight for future models and taxonomies of human-automation interaction.

Evaluation of Graph Pattern Matching Workloads in Graph Analysis Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hong, Seokyong; Lee, Sangkeun; Lim, Seung-Hwan

2016-01-01

Graph analysis has emerged as a powerful method for data scientists to represent, integrate, query, and explore heterogeneous data sources. As a result, graph data management and mining became a popular area of research, and led to the development of plethora of systems in recent years. Unfortunately, the number of emerging graph analysis systems and the wide range of applications, coupled with a lack of apples-to-apples comparisons, make it difficult to understand the trade-offs between different systems and the graph operations for which they are designed. A fair comparison of these systems is a challenging task for the following reasons:more » multiple data models, non-standardized serialization formats, various query interfaces to users, and diverse environments they operate in. To address these key challenges, in this paper we present a new benchmark suite by extending the Lehigh University Benchmark (LUBM) to cover the most common capabilities of various graph analysis systems. We provide the design process of the benchmark, which generalizes the workflow for data scientists to conduct the desired graph analysis on different graph analysis systems. Equipped with this extended benchmark suite, we present performance comparison for nine subgraph pattern retrieval operations over six graph analysis systems, namely NetworkX, Neo4j, Jena, Titan, GraphX, and uRiKA. Through the proposed benchmark suite, this study reveals both quantitative and qualitative findings in (1) implications in loading data into each system; (2) challenges in describing graph patterns for each query interface; and (3) different sensitivity of each system to query selectivity. We envision that this study will pave the road for: (i) data scientists to select the suitable graph analysis systems, and (ii) data management system designers to advance graph analysis systems.« less

Nitric oxide-sensing actuators for modulating structure in lipid-based liquid crystalline drug delivery systems.

PubMed

Liu, Qingtao; Hu, Jinming; Whittaker, Michael R; Davis, Thomas P; Boyd, Ben J

2017-12-15

Herein we report on the development of a nitric oxide-sensing lipid-based liquid crystalline (LLC) system specifically designed to release encapsulated drugs on exposure to NO through a stimulated phase change. A series of nitric oxide (NO)-sensing lipids compatible with phytantriol and GMO cubic phases were designed and synthesized, and utilized in enabling nitric oxide-sensing LLC systems. The nitric oxide (NO)-sensing lipids react with nitric oxide, resulting in hydrolysis of these lipids and phase transition of the LLC system. Specifically, the N-3-aminopyridinyl myristylamine (NAPyM)+phytantriol mixture formed a lamellar phase in excess aqueous environment. The NAPyM+phytantriol LLC responded to the nitric oxide gas as a chemical stimulus which triggers a phase transition from lamellar phase to inverse cubic and hexagonal phase. The nitric oxide-triggered phase transition of the LLC accelerated the release of encapsulated model drug from the LLC bulk phase, resulting in a 15-fold increase in the diffusion coefficient compared to the starting lamellar structure. The nitric oxide-sensing LLC system has potential application in the development of smart medicines to treat nitric oxide implicated diseases. Copyright © 2017 Elsevier Inc. All rights reserved.

Delivering better power: the role of simulation in reducing the environmental impact of aircraft engines.

PubMed

Menzies, Kevin

2014-08-13

The growth in simulation capability over the past 20 years has led to remarkable changes in the design process for gas turbines. The availability of relatively cheap computational power coupled to improvements in numerical methods and physical modelling in simulation codes have enabled the development of aircraft propulsion systems that are more powerful and yet more efficient than ever before. However, the design challenges are correspondingly greater, especially to reduce environmental impact. The simulation requirements to achieve a reduced environmental impact are described along with the implications of continued growth in available computational power. It is concluded that achieving the environmental goals will demand large-scale multi-disciplinary simulations requiring significantly increased computational power, to enable optimization of the airframe and propulsion system over the entire operational envelope. However even with massive parallelization, the limits imposed by communications latency will constrain the time required to achieve a solution, and therefore the position of such large-scale calculations in the industrial design process. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

Scalability, Timing, and System Design Issues for Intrinsic Evolvable Hardware

NASA Technical Reports Server (NTRS)

Hereford, James; Gwaltney, David

2004-01-01

In this paper we address several issues pertinent to intrinsic evolvable hardware (EHW). The first issue is scalability; namely, how the design space scales as the programming string for the programmable device gets longer. We develop a model for population size and the number of generations as a function of the programming string length, L, and show that the number of circuit evaluations is an O(L2) process. We compare our model to several successful intrinsic EHW experiments and discuss the many implications of our model. The second issue that we address is the timing of intrinsic EHW experiments. We show that the processing time is a small part of the overall time to derive or evolve a circuit and that major improvements in processor speed alone will have only a minimal impact on improving the scalability of intrinsic EHW. The third issue we consider is the system-level design of intrinsic EHW experiments. We review what other researchers have done to break the scalability barrier and contend that the type of reconfigurable platform and the evolutionary algorithm are tied together and impose limits on each other.

Marketing alcohol to young people: implications for industry regulation and research policy.

PubMed

Jackson, M C; Hastings, G; Wheeler, C; Eadie, D; Mackintosh, A M

2000-12-01

This paper focuses on the marketing of alcohol to young people in the United Kingdom, but the lessons that emerge have international significance. Alcohol is a global enterprise and recent consolidation means that it is controlled by a decreasing number of expanding multi-nationals. Alcohol companies are able to allocate significant resources to researching consumer preferences, developing new products and promoting them on an international level. Recent years have seen a growth in the value that youth culture attaches to brand labels and symbols and a move away from the healthy-living ethos. The alcohol industry's response to these trends has been to design alcoholic beverages that appeal to young people, using well-informed and precisely targeted marketing strategies. This has led to growing concerns about the implications for public health and a demand for tighter controls to regulate alcohol marketing practices. In the United Kingdom, controls on alcohol are piecemeal and reactive and the current system of voluntary regulation appears ineffective. This paper argues for more research to establish current industry practice and inform the development of a comprehensive regulatory structure and system of monitoring.

Networks as systems.

PubMed

Best, Allan; Berland, Alex; Greenhalgh, Trisha; Bourgeault, Ivy L; Saul, Jessie E; Barker, Brittany

2018-03-19

Purpose The purpose of this paper is to present a case study of the World Health Organization's Global Healthcare Workforce Alliance (GHWA). Based on a commissioned evaluation of GHWA, it applies network theory and key concepts from systems thinking to explore network emergence, effectiveness, and evolution to over a ten-year period. The research was designed to provide high-level strategic guidance for further evolution of global governance in human resources for health (HRH). Design/methodology/approach Methods included a review of published literature on HRH governance and current practice in the field and an in-depth case study whose main data sources were relevant GHWA background documents and key informant interviews with GHWA leaders, staff, and stakeholders. Sampling was purposive and at a senior level, focusing on board members, executive directors, funders, and academics. Data were analyzed thematically with reference to systems theory and Shiffman's theory of network development. Findings Five key lessons emerged: effective management and leadership are critical; networks need to balance "tight" and "loose" approaches to their structure and processes; an active communication strategy is key to create and maintain support; the goals, priorities, and membership must be carefully focused; and the network needs to support shared measurement of progress on agreed-upon goals. Shiffman's middle-range network theory is a useful tool when guided by the principles of complex systems that illuminate dynamic situations and shifting interests as global alliances evolve. Research limitations/implications This study was implemented at the end of the ten-year funding cycle. A more continuous evaluation throughout the term would have provided richer understanding of issues. Experience and perspectives at the country level were not assessed. Practical implications Design and management of large, complex networks requires ongoing attention to key issues like leadership, and flexible structures and processes to accommodate the dynamic reality of these networks. Originality/value This case study builds on growing interest in the role of networks to foster large-scale change. The particular value rests on the longitudinal perspective on the evolution of a large, complex global network, and the use of theory to guide understanding.

Perovskites for Photovoltaics in the Spotlight: Photoinduced Physical Changes and Their Implications.

PubMed

Gottesman, Ronen; Zaban, Arie

2016-02-16

Organic-inorganic halide perovskites are in consensus to revolutionize the field of photovoltaics and optoelectronic devices due to their superior optical and electronic properties which are unprecedented in comparison to those of other solution processed semiconductors. These hybrid materials are used as light absorbers and also as charge carriers which makes them very versatile to be implemented and studied in a multitude of fields. Traditionally, the working paradigm in solar cells and optoelectronic devices' characterization has been that the properties of photovoltaic materials remain stable following illumination of varying times and intensities. However, recently there has been a growing number of reports on prolonged illumination-dependent physical changes in perovskite films and perovskite based devices. The changes are reversible and range from structural transformations and differences in optical characteristics, to an increase in optoelectronic properties and physical parameters. In this Account, we review the physical changes in three reported model systems which display changes under prolonged illumination of light intensities of ∼0.01-1 sun. The three systems are (i) a free-standing perovskite film on a glass substrate, (ii) a symmetrical system with nonselective electrical contacts, and (iii) a working perovskite solar cell (either a planar or a porous structure). We examine each model system and discuss its photoinduced physical changes and conclude with the implications on future experimentation design, data analysis, and characterization that involve organic-inorganic halide perovskites illumination. Since hybrid perovskites are considered to be mixed ionic-electronic conductors in nature, ions that migrate in the perovskite under electrical fields can influence its properties. Therefore, an important distinction is made between photoinduced effects and photo and electric field induced effects. Thus, photoinduced effects are designated as observed effects in illuminated free-standing films or symmetrical devices without selective contacts. In contrast, photo- and electric field induced effects are designated as observed effects under open-circuit potential or during voltage scanning (internal electrical field exists across the device). In the latter case, the two effects are superimposed and it is difficult to evaluate the relative influence of each one (light or electric field). However, we show that the magnitude and the importance of the photoinduced effect are substantial.

Satellite Broadband Revolution: How Latest Ka-Band Systems Will Change the Rules of the Industry. An Interpretation of the Technological Trajectory

NASA Astrophysics Data System (ADS)

Valle, Fabio

The paper analyzes the satellite broadband systems for consumer from the perspective of technological innovation. The suggested interpretation relies upon such concepts as technological paradigm, technological trajectory and salient points. Satellite technology for broadband is a complex system on which each component (i.e. the satellite, the end-user equipment, the on-ground systems and related infrastructure) develops at different speed. Innovation in this industry concentrates recently on satellite space aircraft that seemed to be the component with the highest perceived opportunity for improvement. The industry has designed recently satellite systems with continuous dimensional increase of capacity available, suggesting that there is a technological trajectory in this area, similar to Moore’s law in the computer industry. The implications for industry players, Ka-band systems, and growth of future applications are also examined.

Complex Failure Forewarning System - DHS Conference Proceedings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abercrombie, Robert K; Hively, Lee M; Prowell, Stacy J

2011-01-01

As the critical infrastructures of the United States have become more and more dependent on public and private networks, the potential for widespread national impact resulting from disruption or failure of these networks has also increased. Securing the nation s critical infrastructures requires protecting not only their physical systems but, just as important, the cyber portions of the systems on which they rely. A failure is inclusive of random events, design flaws, and instabilities caused by cyber (and/or physical) attack. One such domain, aging bridges, is used to explain the Complex Structure Failure Forewarning System. We discuss the workings ofmore » such a system in the context of the necessary sensors, command and control and data collection as well as the cyber security efforts that would support this system. Their application and the implications of this computing architecture are also discussed, with respect to our nation s aging infrastructure.« less

Genalogical approaches to ethical implications of informational assimilative integrated discovery systems (AIDS) in business

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pharhizgar, K.D.; Lunce, S.E.

1994-12-31

Development of knowledge-based technological acquisition techniques and customers` information profiles are known as assimilative integrated discovery systems (AIDS) in modern organizations. These systems have access through processing to both deep and broad domains of information in modern societies. Through these systems organizations and individuals can predict future trend probabilities and events concerning their customers. AIDSs are new techniques which produce new information which informants can use without the help of the knowledge sources because of the existence of highly sophisticated computerized networks. This paper has analyzed the danger and side effects of misuse of information through the illegal, unethical andmore » immoral access to the data-base in an integrated and assimilative information system as described above. Cognivistic mapping, pragmatistic informational design gathering, and holistic classifiable and distributive techniques are potentially abusive systems whose outputs can be easily misused by businesses when researching the firm`s customers.« less

Magnetic bearings: Fifty years of progress

NASA Technical Reports Server (NTRS)

Swann, Michael K.

1993-01-01

Magnetic bearings are just beginning to be flown in spacecraft systems, but their development spans more than 50 years. The promise of completely noncontacting, unlubricated rotating systems operating at speeds substantially beyond the range of conventional bearings, and with no wear and virtually no vibration, has provided the incentive to develop magnetic bearing technology for many diverse applications. Earnshaw theorized in 1842 that stable magnetic suspension is not possible in all three spatial directions unless the magnetic field is actively controlled. Since that time, researchers have attempted to successfully support spinning rotors in a stable manner. Development of magnetic suspension systems over the past fifty years has included progress on both passive (permanent magnet) and active (electromagnet) systems. The improvements in bearing load capacity, stiffness, and damping characteristics are traced. The trends in rotor size, rotational kinetic energy, and improvements in active control systems capabilities are also reviewed. Implications of superconductivity on suspension system design and performance are discussed.

Design and Evaluation in eHealth: Challenges and Implications for an Interdisciplinary Field

PubMed Central

2007-01-01

Much has been written about insufficient user involvement in the design of eHealth applications, the lack of evidence demonstrating impact, and the difficulties these bring for adoption. Part of the problem lies in the differing languages, cultures, motives, and operational constraints of producers and evaluators of eHealth systems and services. This paper reflects on the benefits of and barriers to interdisciplinary collaboration in eHealth, focusing particularly on the relationship between software developers and health services researchers. It argues that the common pattern of silo or parallel working may be ameliorated by developing mutual awareness and respect for each others’ methods, epistemologies, and contextual drivers and by recognizing and harnessing potential synergies. Similarities and differences between models and techniques used in both communities are highlighted in order to illustrate the potential for integrated approaches and the strengths of unique paradigms. By sharing information about our research approaches and seeking to actively collaborate in the process of design and evaluation, the aim of achieving technologies that are truly user-informed, fit for context, high quality, and of demonstrated value is more likely to be realized. This may involve embracing new ways of working jointly that are unfamiliar to the stakeholders involved and that challenge disciplinary conventions. It also has policy implications for agencies commissioning research and development in this area. PMID:17537718

A flight by periscope and where it landed.

PubMed

Roscoe, Stanley N; Acosta, Hector M

2008-06-01

This study defines display design factors linking visual accommodation and the perceived size of distant objects. In 1947, in anticipation of augmented contact and sensor-relayed contact displays, a periscope was installed in an airplane to serve as a sensor-based contact display simulator. To achieve normal landing performance, however, the unity image had to be magnified. This successful intervention, first published in 1966 in Human Factors, implicated oculomotor mechanisms and higher perceptual functions and became the observational basis for a series of investigative hypotheses. Observers registered the perceived size of the collimated image of a "moon" by adjusting a disk of light while alternatively providing optometric measurements of accommodative distance. Various investigators found high correlations between focal distances and perceived moon sizes. The simulated moon provided a superior vehicle for revealing the relationship between focal distance and perceived size and the factors affecting both. The operational display design implications and the possibility of a partial explanation for the moon illusion provided the motivation for an important doctoral research project involving eight factors that affect both focal distance and perceived size. The investigation reaffirmed that virtual images, as found in head-up and head-mounted displays (HUDs and HMDs, respectively), do not consistently draw focus to optical infinity and that a variety of factors necessarily manipulated by display designers and present in many operational systems can affect visual performance partially through the mediation of accommodation.

Impact of cooking and home food preparation interventions among adults: outcomes and implications for future programs.

PubMed

Reicks, Marla; Trofholz, Amanda C; Stang, Jamie S; Laska, Melissa N

2014-01-01

Cooking programs are growing in popularity; however, an extensive review has not examined their overall impact. Therefore, this study reviewed previous research on cooking/home food preparation interventions and diet and health-related outcomes among adults and identified implications for practice and research. Literature review and descriptive summative method. Dietary intake, knowledge/skills, cooking attitudes and self-efficacy/confidence, health outcomes. Articles evaluating the effectiveness of interventions that included cooking/home food preparation as the primary aim (January, 1980 through December, 2011) were identified via Ovid MEDLINE, Agricola, and Web of Science databases. Studies grouped according to design and outcomes were reviewed for validity using an established coding system. Results were summarized for several outcome categories. Of 28 studies identified, 12 included a control group with 6 as nonrandomized and 6 as randomized controlled trials. Evaluation was done postintervention for 5 studies, pre- and postintervention for 23, and beyond postintervention for 15. Qualitative and quantitative measures suggested a positive influence on main outcomes. However, nonrigorous study designs, varying study populations, and the use of nonvalidated assessment tools limited stronger conclusions. Well-designed studies are needed that rigorously evaluate long-term impact on cooking behavior, dietary intake, obesity and other health outcomes. Copyright © 2014 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

Radiation protection measures: Implications on the design of neurosurgery operating rooms.

PubMed

Delgado-López, Pedro David; Sánchez-Jiménez, Javier; Herrero-Gutiérrez, Ana Isabel; Inclán-Cuesta, María Teresa; Corrales-García, Eva María; Martín-Alonso, Javier; Galacho-Harriero, Ana María; Rodríguez-Salazar, Antonio

To describe pros and cons of some radiation protection measures and the implications on the design of a neurosurgery operating room. Concurring with the acquisition and use of an O-arm device, a structural remodeling of our neurosurgery operating room was carried out. The theater was enlarged, the shielding was reinforced and a foldable leaded screen was installed inside the operating room. Radiation doses were measured in front of and behind the screen. The screen provides whole-body radiation protection for all the personnel inside the theater (effective dose <5μSv at 2,5 m from the gantry per O-arm exploration; 0,0μSv received behind the screen per O-arm exploration; and undetectable cumulative annual radiation dose behind the screen), obviates the need for leaded aprons and personal dosimeters, and minimizes the circulation of personnel. Enlarging the size of the operating room allows storing the equipment inside and minimizes the risk of collision and contamination. Rectangular rooms provide greater distance from the source of radiation. Floor, ceiling and walls shielding, a rectangular-shaped and large enough theater, the presence of a foldable leaded screen, and the security systems precluding an unexpected irruption into the operating room during irradiation are relevant issues to consider when designing a neurosurgery operating theater. Copyright © 2018 Sociedad Española de Neurocirugía. Publicado por Elsevier España, S.L.U. All rights reserved.

Developing and theoretically justifying innovative organizational practices in health information assurance

NASA Astrophysics Data System (ADS)

Collmann, Jeff R.

2003-05-01

This paper justifies and explains current efforts in the Military Health System (MHS) to enhance information assurance in light of the sociological debate between "Normal Accident" (NAT) and "High Reliability" (HRT) theorists. NAT argues that complex systems such as enterprise health information systems display multiple, interdependent interactions among diverse parts that potentially manifest unfamiliar, unplanned, or unexpected sequences that operators may not perceive or immediately understand, especially during emergencies. If the system functions rapidly with few breaks in time, space or process development, the effects of single failures ramify before operators understand or gain control of the incident thus producing catastrophic accidents. HRT counters that organizations with strong leadership support, continuous training, redundant safety features and "cultures of high reliability" contain the effects of component failures even in complex, tightly coupled systems. Building highly integrated, enterprise-wide computerized health information management systems risks creating the conditions for catastrophic breaches of data security as argued by NAT. The data security regulations of the Health Insurance Portability and Accountability Act of 1996 (HIPAA) implicitly depend on the premises of High Reliability Theorists. Limitations in HRT thus have implications for both safe program design and compliance efforts. MHS and other health care organizations should consider both NAT and HRT when designing and deploying enterprise-wide computerized health information systems.

System implications of aperture-shade design for the SIRTF Observatory

NASA Technical Reports Server (NTRS)

Lee, J. H.; Brooks, W. F.; Maa, S.

1987-01-01

The 1-m-aperture Space Infrared Telescope Facility (SIRTF) will operate with a sensitivity limited only by the zodiacal background. This sensitivity requirement places severe restrictions on the amount of stray light which can reach the focal plane from off-axis sources such as the sun or earth limb. In addition, radiation from these sources can degrade the lifetime of the telescope and instrument cryogenic system which is now planned for two years before the first servicing. Since the aperture of the telescope represents a break in the telescope insulation system and is effectively the first element in the optical train, the aperture shade is a key system component. The mass, length, and temperature of the shade should be minimized to reduce system cost while maximizing the telescope lifetime and stray light performance. The independent geometric parameters that characterize an asymmetrical shade for a 600 km, 28 deg orbit were identified, and the system sensitivity to the three most important shade parameters were explored. Despite the higher heat loads compared to previously studied polar orbit missions, the analysis determined that passive radiators of a reasonable size are sufficient to meet the system requirements. An optimized design for the SIRTF mission, based on the sensitivity analysis, is proposed.

Architecture for knowledge-based and federated search of online clinical evidence.

PubMed

Coiera, Enrico; Walther, Martin; Nguyen, Ken; Lovell, Nigel H

2005-10-24

It is increasingly difficult for clinicians to keep up-to-date with the rapidly growing biomedical literature. Online evidence retrieval methods are now seen as a core tool to support evidence-based health practice. However, standard search engine technology is not designed to manage the many different types of evidence sources that are available or to handle the very different information needs of various clinical groups, who often work in widely different settings. The objectives of this paper are (1) to describe the design considerations and system architecture of a wrapper-mediator approach to federate search system design, including the use of knowledge-based, meta-search filters, and (2) to analyze the implications of system design choices on performance measurements. A trial was performed to evaluate the technical performance of a federated evidence retrieval system, which provided access to eight distinct online resources, including e-journals, PubMed, and electronic guidelines. The Quick Clinical system architecture utilized a universal query language to reformulate queries internally and utilized meta-search filters to optimize search strategies across resources. We recruited 227 family physicians from across Australia who used the system to retrieve evidence in a routine clinical setting over a 4-week period. The total search time for a query was recorded, along with the duration of individual queries sent to different online resources. Clinicians performed 1662 searches over the trial. The average search duration was 4.9 +/- 3.2 s (N = 1662 searches). Mean search duration to the individual sources was between 0.05 s and 4.55 s. Average system time (ie, system overhead) was 0.12 s. The relatively small system overhead compared to the average time it takes to perform a search for an individual source shows that the system achieves a good trade-off between performance and reliability. Furthermore, despite the additional effort required to incorporate the capabilities of each individual source (to improve the quality of search results), system maintenance requires only a small additional overhead.

Cost Scaling of a Real-World Exhaust Waste Heat Recovery Thermoelectric Generator: A Deeper Dive

NASA Technical Reports Server (NTRS)

Hendricks, Terry J.; Yee, Shannon; LeBlanc, Saniya

2015-01-01

Cost is equally important to power density or efficiency for the adoption of waste heat recovery thermoelectric generators (TEG) in many transportation and industrial energy recovery applications. In many cases the system design that minimizes cost (e.g., the $/W value) can be very different than the design that maximizes the system's efficiency or power density, and it is important to understand the relationship between those designs to optimize TEG performance-cost compromises. Expanding on recent cost analysis work and using more detailed system modeling, an enhanced cost scaling analysis of a waste heat recovery thermoelectric generator with more detailed, coupled treatment of the heat exchangers has been performed. In this analysis, the effect of the heat lost to the environment and updated relationships between the hot-side and cold-side conductances that maximize power output are considered. This coupled thermal and thermoelectric treatment of the exhaust waste heat recovery thermoelectric generator yields modified cost scaling and design optimization equations, which are now strongly dependent on the heat leakage fraction, exhaust mass flow rate, and heat exchanger effectiveness. This work shows that heat exchanger costs most often dominate the overall TE system costs, that it is extremely difficult to escape this regime, and in order to achieve TE system costs of $1/W it is necessary to achieve heat exchanger costs of $1/(W/K). Minimum TE system costs per watt generally coincide with maximum power points, but Preferred TE Design Regimes are identified where there is little cost penalty for moving into regions of higher efficiency and slightly lower power outputs. These regimes are closely tied to previously-identified low cost design regimes. This work shows that the optimum fill factor Fopt minimizing system costs decreases as heat losses increase, and increases as exhaust mass flow rate and heat exchanger effectiveness increase. These findings have profound implications on the design and operation of various thermoelectric (TE) waste heat 3 recovery systems. This work highlights the importance of heat exchanger costs on the overall TEG system costs, quantifies the possible TEG performance-cost domain space based on heat exchanger effects, and provides a focus for future system research and development efforts.

Beam dynamic simulations of the CLIC crab cavity and implications on the BDS

NASA Astrophysics Data System (ADS)

Shinton, I. R. R.; Burt, G.; Glasman, C. J.; Jones, R. M.; Wolski, A.

2011-11-01

The Compact Linear Collider (CLIC) is a proposed electron positron linear collider design aiming to achieve a centre of mass energy of up to 3 TeV. The main accelerating structures in CLIC operate at an X-band frequency of 11.994 GHz with an accelerating gradient of 100 MV/m. The present design requires the beams to collide at a small crossing angle of 10 mrad per line giving a resultant overall crossing angle of 20 mrad. Transverse deflecting cavities, referred to as "Crab cavities", are installed in the beam delivery system (BDS) of linear collider designs in order to ensure the final luminosity at the interaction point (IP) is comparable to that in a head on collision. We utilise the beam tracking code PLACET combined with the beam-beam code GUINEA-PIG to calculate the resulting luminosity at the IP. We follow a similar tuning procedure to that used for the design of the ILC crab cavities and anitcrab cavities. However an unexpected loss in luminosity of 10% was observed for the 20 mrad design was observed. It was discovered that the action of the crab cavities can affect the geometric aberrations resulting from the sextupoles used to correct chromatic effects in the beam delivery system. This has direct consequences regarding the design of the present CLIC BDS.

Cyberspace as a Complex Adaptive System and the Policy and Operational Implications for Cyber Warfare

DTIC Science & Technology

2014-05-22

CYBERSPACE AS A COMPLEX ADAPTIVE SYSTEM AND THE POLICY AND OPERTIONAL IMPLICATIONS FOR CYBER WARFARE A Monograph by Major Albert O. Olagbemiro...serves the US, especially in regards to the protect ion o f the 1S. SUBJECT TERMS omplex Adaptive System, Cyberspace, lnfosphere, Cyber Warfare ber...System and the Policy and Operational Implications for Cyber Warfare Approved by: __________________________________, Monograph Director Jeffrey

Nature of Technology: Implications for design, development, and enactment of technological tools in school science classrooms

NASA Astrophysics Data System (ADS)

Waight, Noemi; Abd-El-Khalick, Fouad

2012-12-01

This position paper provides a theory-based explanation informed by philosophy of technology (PoT) of the recurrent documented patterns often associated with attempts to enact technology-supported, inquiry-based approaches in precollege science classrooms. Understandings derived from the history of technological development in other domains (e.g. medicine, transportation, and warfare) reveal numerous parallels that help to explain these recurrent patterns. Historical analyses of major technologies reveal a conglomerate of factors that interact to produce benefits, as well as intended and unintended consequences. On a macro-scale, PoT facilitates understandings of how technologies interact and are impacted by individuals, society, institutions, economy, politics, and culture. At the micro-level, and most relevant to science education, PoT engages the inherent nature of technology along a number of key dimensions: role of culture and values, notions of technological progression, technology as part of systems, technological diffusion, technology as a fix, and the notions of expertise. Overall, the present analysis has implications for the design, development, implementation, and adoption of technological tools for use in precollege science education, and highlights the role of technology as both artifact and process.

Head posture measurements among work vehicle drivers and implications for work and workplace design.

PubMed

Eklund, J; Odenrick, P; Zettergren, S; Johansson, H

1994-04-01

An increased risk of musculoskeletal disorders, e.g. from the neck region, has been found among professional drivers of work vehicles. The purpose of this study was to identify causes of postural load and implications for vehicle design and work tasks. A second purpose was to develop the methods for measurement and analysis of head postures. Field measurements of head postures for drivers of fork lift trucks, forestry machines, and cranes were carried out. The equipment used was an electric goniometer measurement system, containing a mechanical transmission between the head and the upper trunk. Methods for data presentation and quantification were developed. The results showed that rotatable and movable driver cabins improved head postures and viewing angles substantially. Narrow window frame structures and large, optimally-placed windows were also advantageous. The steering wheel, controls, and a high backrest restricted shoulder rotation, which increased head rotation in unfavourable viewing angles. Improved workspace layouts and work organization factors such as job enlargement decreased the influence of strenuous postures. The results also showed that head postures should be analysed in two or three dimensions simultaneously, otherwise the postures taken will be underestimated in relation to the maximal voluntary movement.

Impaired periamygdaloid-cortex prodynorphin is characteristic of opiate addiction and depression.

PubMed

Anderson, Sarah Ann R; Michaelides, Michael; Zarnegar, Parisa; Ren, Yanhua; Fagergren, Pernilla; Thanos, Panayotis K; Wang, Gene-Jack; Bannon, Michael; Neumaier, John F; Keller, Eva; Volkow, Nora D; Hurd, Yasmin L

2013-12-01

Negative affect is critical for conferring vulnerability to opiate addiction as reflected by the high comorbidity of opiate abuse with major depressive disorder (MDD). Rodent models implicate amygdala prodynorphin (Pdyn) as a mediator of negative affect; however, evidence of PDYN involvement in human negative affect is limited. Here, we found reduced PDYN mRNA expression in the postmortem human amygdala nucleus of the periamygdaloid cortex (PAC) in both heroin abusers and MDD subjects. Similar to humans, rats that chronically self-administered heroin had reduced Pdyn mRNA expression in the PAC at a time point associated with a negative affective state. Using the in vivo functional imaging technology DREAMM (DREADD-assisted metabolic mapping, where DREADD indicates designer receptors exclusively activated by designer drugs), we found that selective inhibition of Pdyn-expressing neurons in the rat PAC increased metabolic activity in the extended amygdala, which is a key substrate of the extrahypothalamic brain stress system. In parallel, PAC-specific Pdyn inhibition provoked negative affect-related physiological and behavioral changes. Altogether, our translational study supports a functional role for impaired Pdyn in the PAC in opiate abuse through activation of the stress and negative affect neurocircuitry implicated in addiction vulnerability.

Trading Later Rewards for Current Pleasure: Pornography Consumption and Delay Discounting.

PubMed

Negash, Sesen; Sheppard, Nicole Van Ness; Lambert, Nathaniel M; Fincham, Frank D

2016-01-01

Internet pornography is a multi-billion-dollar industry that has grown increasingly accessible. Delay discounting involves devaluing larger, later rewards in favor of smaller, more immediate rewards. The constant novelty and primacy of sexual stimuli as particularly strong natural rewards make Internet pornography a unique activator of the brain's reward system, thereby having implications for decision-making processes. Based on theoretical studies of evolutionary psychology and neuroeconomics, two studies tested the hypothesis that consuming Internet pornography would relate to higher rates of delay discounting. Study 1 used a longitudinal design. Participants completed a pornography use questionnaire and a delay discounting task at Time 1 and then again four weeks later. Participants reporting higher initial pornography use demonstrated a higher delay discounting rate at Time 2, controlling for initial delay discounting. Study 2 tested for causality with an experimental design. Participants were randomly assigned to abstain from either their favorite food or pornography for three weeks. Participants who abstained from pornography use demonstrated lower delay discounting than participants who abstained from their favorite food. The finding suggests that Internet pornography is a sexual reward that contributes to delay discounting differently than other natural rewards. Theoretical and clinical implications of these studies are highlighted.

An adaptive and generalizable closed-loop system for control of medically induced coma and other states of anesthesia

NASA Astrophysics Data System (ADS)

Yang, Yuxiao; Shanechi, Maryam M.

2016-12-01

Objective. Design of closed-loop anesthetic delivery (CLAD) systems is an important topic, particularly for medically induced coma, which needs to be maintained for long periods. Current CLADs for medically induced coma require a separate offline experiment for model parameter estimation, which causes interruption in treatment and is difficult to perform. Also, CLADs may exhibit bias due to inherent time-variation and non-stationarity, and may have large infusion rate variations at steady state. Finally, current CLADs lack theoretical performance guarantees. We develop the first adaptive CLAD for medically induced coma, which addresses these limitations. Further, we extend our adaptive system to be generalizable to other states of anesthesia. Approach. We designed general parametric pharmacodynamic, pharmacokinetic and neural observation models with associated guidelines, and derived a novel adaptive controller. We further penalized large steady-state drug infusion rate variations in the controller. We derived theoretical guarantees that the adaptive system has zero steady-state bias. Using simulations that resembled real time-varying and noisy environments, we tested the closed-loop system for control of two different anesthetic states, burst suppression in medically induced coma and unconsciousness in general anesthesia. Main results. In 1200 simulations, the adaptive system achieved precise control of both anesthetic states despite non-stationarity, time-variation, noise, and no initial parameter knowledge. In both cases, the adaptive system performed close to a baseline system that knew the parameters exactly. In contrast, a non-adaptive system resulted in large steady-state bias and error. The adaptive system also resulted in significantly smaller steady-state infusion rate variations compared to prior systems. Significance. These results have significant implications for clinically viable CLAD design for a wide range of anesthetic states, with potential cost-saving and therapeutic benefits.

An adaptive and generalizable closed-loop system for control of medically induced coma and other states of anesthesia.

PubMed

Yang, Yuxiao; Shanechi, Maryam M

2016-12-01

Design of closed-loop anesthetic delivery (CLAD) systems is an important topic, particularly for medically induced coma, which needs to be maintained for long periods. Current CLADs for medically induced coma require a separate offline experiment for model parameter estimation, which causes interruption in treatment and is difficult to perform. Also, CLADs may exhibit bias due to inherent time-variation and non-stationarity, and may have large infusion rate variations at steady state. Finally, current CLADs lack theoretical performance guarantees. We develop the first adaptive CLAD for medically induced coma, which addresses these limitations. Further, we extend our adaptive system to be generalizable to other states of anesthesia. We designed general parametric pharmacodynamic, pharmacokinetic and neural observation models with associated guidelines, and derived a novel adaptive controller. We further penalized large steady-state drug infusion rate variations in the controller. We derived theoretical guarantees that the adaptive system has zero steady-state bias. Using simulations that resembled real time-varying and noisy environments, we tested the closed-loop system for control of two different anesthetic states, burst suppression in medically induced coma and unconsciousness in general anesthesia. In 1200 simulations, the adaptive system achieved precise control of both anesthetic states despite non-stationarity, time-variation, noise, and no initial parameter knowledge. In both cases, the adaptive system performed close to a baseline system that knew the parameters exactly. In contrast, a non-adaptive system resulted in large steady-state bias and error. The adaptive system also resulted in significantly smaller steady-state infusion rate variations compared to prior systems. These results have significant implications for clinically viable CLAD design for a wide range of anesthetic states, with potential cost-saving and therapeutic benefits.

Examining the Usability of Touch Screen Gestures for Older and Younger Adults.

PubMed

Gao, Qin; Sun, Qiqi

2015-08-01

We examined the usability issues associated with four touch screen gestures (clicking, dragging, zooming, and rotating) among older and younger users. It is especially important to accommodate older users' characteristics to ensure the accessibility of information and services that are important to their quality of life. Forty older and 40 younger participants completed four experiments, each of which focused on one gesture. The effects of age, type of touch screen (surface acoustic wave vs. optical), inclination angle (30°, 45°, 60°, and 75°), and user interface factors (clicking: button size and spacing; dragging: dragging direction and distance; zooming: design of zooming gesture; rotating: design of rotating gesture) on user performance and satisfaction were examined. Button sizes that are larger than 15.9 × 9.0 mm led to better performance and higher satisfaction. The effect of spacing was significant only when the button size was notably small or large. Rightward and downward dragging were preferred to leftward and upward dragging, respectively. The younger participants favored direct manipulation gestures using multiple fingers, whereas the older participants preferred the click-to design. The older participants working with large inclination angles of 60° to 75° reported a higher level of satisfaction than the older participants working with smaller angles. We proposed a set of design guidelines for touch screen user interfaces and discussed implications for the selection of appropriate technology and the configuration of the workspace. The implications are useful for the design of large touch screen applications, such as desktop computers, information kiosks, and health care support systems. © 2015, Human Factors and Ergonomics Society.

Implications of sampling design and sample size for national carbon accounting systems.

PubMed

Köhl, Michael; Lister, Andrew; Scott, Charles T; Baldauf, Thomas; Plugge, Daniel

2011-11-08

Countries willing to adopt a REDD regime need to establish a national Measurement, Reporting and Verification (MRV) system that provides information on forest carbon stocks and carbon stock changes. Due to the extensive areas covered by forests the information is generally obtained by sample based surveys. Most operational sampling approaches utilize a combination of earth-observation data and in-situ field assessments as data sources. We compared the cost-efficiency of four different sampling design alternatives (simple random sampling, regression estimators, stratified sampling, 2-phase sampling with regression estimators) that have been proposed in the scope of REDD. Three of the design alternatives provide for a combination of in-situ and earth-observation data. Under different settings of remote sensing coverage, cost per field plot, cost of remote sensing imagery, correlation between attributes quantified in remote sensing and field data, as well as population variability and the percent standard error over total survey cost was calculated. The cost-efficiency of forest carbon stock assessments is driven by the sampling design chosen. Our results indicate that the cost of remote sensing imagery is decisive for the cost-efficiency of a sampling design. The variability of the sample population impairs cost-efficiency, but does not reverse the pattern of cost-efficiency of the individual design alternatives. Our results clearly indicate that it is important to consider cost-efficiency in the development of forest carbon stock assessments and the selection of remote sensing techniques. The development of MRV-systems for REDD need to be based on a sound optimization process that compares different data sources and sampling designs with respect to their cost-efficiency. This helps to reduce the uncertainties related with the quantification of carbon stocks and to increase the financial benefits from adopting a REDD regime.

Modeling workflow to design machine translation applications for public health practice

PubMed Central

Turner, Anne M.; Brownstein, Megumu K.; Cole, Kate; Karasz, Hilary; Kirchhoff, Katrin

2014-01-01

Objective Provide a detailed understanding of the information workflow processes related to translating health promotion materials for limited English proficiency individuals in order to inform the design of context-driven machine translation (MT) tools for public health (PH). Materials and Methods We applied a cognitive work analysis framework to investigate the translation information workflow processes of two large health departments in Washington State. Researchers conducted interviews, performed a task analysis, and validated results with PH professionals to model translation workflow and identify functional requirements for a translation system for PH. Results The study resulted in a detailed description of work related to translation of PH materials, an information workflow diagram, and a description of attitudes towards MT technology. We identified a number of themes that hold design implications for incorporating MT in PH translation practice. A PH translation tool prototype was designed based on these findings. Discussion This study underscores the importance of understanding the work context and information workflow for which systems will be designed. Based on themes and translation information workflow processes, we identified key design guidelines for incorporating MT into PH translation work. Primary amongst these is that MT should be followed by human review for translations to be of high quality and for the technology to be adopted into practice. Counclusion The time and costs of creating multilingual health promotion materials are barriers to translation. PH personnel were interested in MT's potential to improve access to low-cost translated PH materials, but expressed concerns about ensuring quality. We outline design considerations and a potential machine translation tool to best fit MT systems into PH practice. PMID:25445922

Decision-making strategies: ignored to the detriment of healthcare training and delivery?

PubMed Central

Desmond, Chris; Brubaker, Kathryn A.; Ellner, Andrew L.

2013-01-01

Context: People do not always make health-related decisions which reflect their best interest – best interest being defined as the decision they would make if they carefully considered the options and fully understood the information available. A substantial literature has developed in behavioral economics and social psychology that seeks to elucidate the patterns in individual decision-making. While this is particularly relevant to healthcare, the insights from these fields have only been applied in a limited way. To address the health challenges of the twenty-first century, healthcare providers and healthcare systems designers need to more fully understand how individuals are making decisions. Methods: We provide an overview of the theories of behavioral economics and social psychology that relate to how individuals make health-related decisions. The concentration on health-related decisions leads to a focus on three topics: (1) mental shortcuts and motivated reasoning; (2) implications of time; and (3) implications of affect. The first topic is relevant because health-related decisions are often made in a hurry without a full appreciation of the implications and the deliberation they warrant. The second topic is included because the link between a decision and its health-related outcomes can involve a significant time lag. The final topic is included because health and affect are so often linked. Findings: The literature reviewed has implications for healthcare training and delivery. Selection for medical training must consider the skills necessary to understand and adapt to how patients make decisions. Training on the insights garnered from behavioral economics and social psychology would better prepare healthcare providers to effectively support their clients to lead healthy lives. Healthcare delivery should be structured to respond to the way in which decisions are made. Conclusions: These patterns in decision-making call into question basic assumptions our healthcare system makes about the best way to treat patients and deliver care. This literature has implications for the way we train physicians and deliver care. PMID:25264501