Science.gov

Sample records for system pas port

  1. Peripheral Insertion of a Central Venous Access Device Under Fluoroscopic Guidance Using a Peripherally Accessed System (PAS) Port in the Forearm

    SciTech Connect

    Hata, Yasuhiro; Morita, Sojiro; Morita, Yoshitaka; Awatani, Toshihide; Takasaki, Motohiro; Horimi, Tadashi; Ozawa, Zen

    1998-05-15

    Purpose: We describe the technique, efficacy, and complications of fluoroscopy-guided implantation of a central venous access device using a peripherally accessed system (PAS) port via the forearm. Methods: Beginning in July 1994, 105 central venous access devices were implanted in 104 patients for the long-term infusion of antibiotics or antineoplasmic agents, blood products, or parenteral nutrition. The devices was inserted under fluoroscopic guidance with real-time venography from a peripheral route. Results: All ports were successfully implanted. There were no procedure-related complications. No thrombosis or local infection was observed; however, in six patients catheter-related phlebitis occurred. Conclusion: Fluoroscopy-guided implantation of a central venous access device using a PAS port via the forearm is safe and efficacious, and injection of contrast medium through a peripheral IV catheter before introduction of the catheter helps to avoid catheter-related phlebitis.

  2. Port Operational Marine Observing System

    NASA Astrophysics Data System (ADS)

    Palazov, A.; Stefanov, A.; Slabakova, V.; Marinova, V.

    2009-04-01

    The Port Operational Marine Observing System (POMOS) is a network of distributed sensors and centralized data collecting, processing and distributing unit. The system is designed to allow for the real-time assessment of weather and marine conditions throughout the major Bulgarian ports: Varna, Burgas and Balchik, supporting thereby Maritime administration to secure safety navigation in bays, canals and ports. Real-time information within harbors is obtained using various sensors placed at thirteen strategic locations to monitor the current state of the environment. The most important for navigation weather and sea-state parameters are measured: wind speed and direction, air temperature, relative humidity, atmospheric pressure, visibility, solar radiation, water temperature and salinity, sea level, currents speed and direction, mean wave's parameters. The system consist of: 11 weather stations (3 with extra solar radiation and 4 with extra visibility measurement), 9 water temperature and salinity sensors, 9 sea-level stations, two sea currents and waves stations and two canal currents stations. All sensors are connected to communication system which provides direct intranet access to the instruments. Every 15 minutes measured data is transmitted in real-time to the central collecting system, where data is collected, processed and stored in database. Database is triple secured to prevent data losses. Data collection system is double secured. Measuring system is secured against short power failure and instability. Special software is designed to collect, store, process and present environmental data and information on different user-friendly screens. Access to data and information is through internet/intranet with the help of browsers. Actual data from all measurements or from separate measuring place can be displayed on the computer screens as well as data for the last 24 hours. Historical data are available using report server for extracting data for selectable

  3. Space Data Systems Applications in the iPAS Pathfinder Laboratory

    NASA Technical Reports Server (NTRS)

    Rich, Tom

    2013-01-01

    The iPAS is an integrated hardware/software test and evaluation environment, in support of current and future spacecraft development The iPAS has two main elements. A common avionics, hardware, and software architecture that can be applied over various missions. A common testbed framework that supports integrated hardware/software testing for a variety of applications. The iPAS includes the following (non-flight qualified) components: Core Flight Software (from GSFC). Commercially available Proton and S950 Flight Computer boards. Power and propulsion systems based on representative flight hardware. A realistic flight deck based on the Multi-Purpose Crew Vehicle (MPCV), including realistic flight controls and displays. A Space Data System based on CCSDS protocols.

  4. An integrated mobile system for port security

    SciTech Connect

    Cester, D.; Fabris, D.; Lunardon, M.; Moretto, S.; Nebbia, G.; Pesente, S.; Stevanato, L.; Viesti, G.; Neri, F.; Petrucci, S.; Selmi, S.; Tintori, C.

    2011-07-01

    An integrated mobile system for port security is presented. The system is designed to perform active investigations, by using the tagged neutron inspection technique, of suspect dangerous materials as well as passive measurements of neutrons and gamma rays to search and identify radioactive and special nuclear materials. (authors)

  5. Development of five port reflectometer for reflection based sensing system

    NASA Astrophysics Data System (ADS)

    Baharuddin, S. A.; Cheng, E. M.; Lee, K. Y.; Zaaba, S. K.; Syahirah, K. N.; Abbas, Z.; Nasir, N. F. Mohd; Afendi, M.; Zakaria, Z.

    2017-03-01

    Five-Port Reflectometer is a microwave passivedevice where it implements the six-port algorithm to measure the complex reflection coefficient of material under test (MUT) through reflection on interface between MUT and microwave sensor. Initially, the Six-Port Reflectometer (SPR) was introduced by Engen in 1977 and major component used insix-port technique was designed in many types. When Riblet and Hanssonproposed ring junction with 5 ports only on 1981. Six ports ring junction has been reduced to five ports. In this paper, a dual frequency five ports ring junction circuit was designed, simulated and fabricated for reflection based sensing system. The fabricated five port ring junction is operating at frequencies of 0.64 GHz and 2.42 GHz. The measured result had good agreement with the simulated results for dual frequencies in terms of magnitude and phase.

  6. iPAS: AES Flight System Technology Maturation for Human Spaceflight

    NASA Technical Reports Server (NTRS)

    Othon, William L.

    2014-01-01

    In order to realize the vision of expanding human presence in space, NASA will develop new technologies that can enable future crewed spacecraft to go far beyond Earth orbit. These technologies must be matured to the point that future project managers can accept the risk of incorporating them safely and effectively within integrated spacecraft systems, to satisfy very challenging mission requirements. The technologies must also be applied and managed within an operational context that includes both on-board crew and mission support on Earth. The Advanced Exploration Systems (AES) Program is one part of the NASA strategy to identify and develop key capabilities for human spaceflight, and mature them for future use. To support this initiative, the Integrated Power Avionics and Software (iPAS) environment has been developed that allows engineers, crew, and flight operators to mature promising technologies into applicable capabilities, and to assess the value of these capabilities within a space mission context. This paper describes the development of the integration environment to support technology maturation and risk reduction, and offers examples of technology and mission demonstrations executed to date.

  7. 78 FR 7336 - Safety Zone; Alaska Marine Highway System Port Valdez Ferry Terminal, Port Valdez; Valdez, AK

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-01

    ... Ferry Terminal, Port Valdez; Valdez, AK AGENCY: Coast Guard, DHS. ACTION: Notice of Proposed Rulemaking... Valdez within a 200-yard radius of the Alaska Marine Highway System (AMHS) Port Valdez Ferry Terminal... 200-yards of the AMHS Port Valdez Ferry Terminal whenever an AMHS ferry is underway within 200...

  8. Physical Oceanographic Real-Time System (PORTS) (Invited)

    NASA Astrophysics Data System (ADS)

    Wright, D.

    2013-12-01

    The 1999 Assessment of U.S. Marine Transportation System report to Congress noted that the greatest safety concern voiced by the maritime community was the availability of timely, accurate, and reliable navigation information, including real time environment data. Real time oceanographic and meteorological data, along with other navigation tools, gives the mariner a good situational understanding of their often challenging operational environment, to make the best safety of life and property decisions. The National Oceanic and Atmospheric Administration's (NOAA) Physical Oceanographic Real Time System (PORTS) was developed in response to accidents like the Sunshine Skyway Bridge collision in Tampa, FL in 1980, where the lack of accurate, reliable and timely environmental conditions directly contributed to an accident that resulted in a high loss of life and property. Since that time, PORTS has expanded to over 20 locations around the country, and its capabilities have been continually expanded and improved as well. PORTS primary mission is to prevent maritime accidents. Preventing an accident from occurring is the most cost effective approach and the best way to avoid damage to the environment. When accidents do occur, PORTS data is used to improve the effectiveness of response efforts by providing input for trajectory models and real time conditions for response efforts. However, benefits derived from PORTS go well beyond navigation safety. Another large benefit to the local maritime community is potential efficiencies in optimizing use of the existing water column. PORTS provides information that can be used to make economic decisions to add or offload cargo to a vessel and/or to maintain or adjust transit schedules based upon availability of water depth, strength/timing of tidal currents, and other conditions. PORTS data also helps improve and validate local National Weather Service marine weather forecasts. There are many benefits beyond the local maritime

  9. Polyacene (PAS) batteries

    SciTech Connect

    Yata, Shizukuni

    1995-12-31

    Human activity has been recognized to seriously influence the earth`s environment. Therefore, a clean battery with long-life and safe-use is important and its demand has increased at present. Of the ``clean`` batteries proposed, polymer batteries are the best candidate for environment-friendly and highly-reliable because they do not contain a toxic heavy metal such as cadmium and mercury. The author has developed polyacenic semiconductor (PAS) materials prepared from pyrolytic treatment of phenol-formaldehyde resin. PAS is a conductive polymer which can be doped to either P-type or N-type quite successfully and is extremely resistant to oxidation, chemicals and heat. Because PAS can be doped with both electron acceptors and donors, it is possible to design an all polymer battery using PAS for both electrodes. By taking advantage of stability of PAS, PAS battery can embody greater and longer-lasting reliability than conventional secondary batteries. Usually, lithium metal, which is used in the lithium secondary batteries for an anode-active material, makes dendrites during charging/discharging cycles, which limits the life of the batteries to a few dozen cycles. Furthermore, the dendrites of lithium metal have a safety problem because of its reactivity with water. An investigation of a new anode-material aiming to replace the lithium metal with another safety electrode, is one of the major trend, in secondary batteries. In this paper, the author first describes the structure and the properties of the PAS material, and second its application as an electrode material for rechargeable batteries.

  10. Finite-time thermodynamics of port-Hamiltonian systems

    NASA Astrophysics Data System (ADS)

    Delvenne, Jean-Charles; Sandberg, Henrik

    2014-01-01

    In this paper, we identify a class of time-varying port-Hamiltonian systems that is suitable for studying problems at the intersection of statistical mechanics and control of physical systems. Those port-Hamiltonian systems are able to modify their internal structure as well as their interconnection with the environment over time. The framework allows us to prove the First and Second Laws of thermodynamics, but also lets us apply results from optimal and stochastic control theory to physical systems. In particular, we show how to use linear control theory to optimally extract work from a single heat source over a finite time interval in the manner of Maxwell’s demon. Furthermore, the optimal controller is a time-varying port-Hamiltonian system, which can be physically implemented as a variable linear capacitor and transformer. We also use the theory to design a heat engine operating between two heat sources in finite-time Carnot-like cycles of maximum power, and we compare those two heat engines.

  11. Refrigeration system having dual suction port compressor

    DOEpatents

    Wu, Guolian

    2016-01-05

    A cooling system for appliances, air conditioners, and other spaces includes a compressor, and a condenser that receives refrigerant from the compressor. The system also includes an evaporator that receives refrigerant from the condenser. Refrigerant received from the condenser flows through an upstream portion of the evaporator. A first portion of the refrigerant flows to the compressor without passing through a downstream portion of the evaporator, and a second portion of the refrigerant from the upstream portion of the condenser flows through the downstream portion of the evaporator after passing through the upstream portion of the evaporator. The second portion of the refrigerant flows to the compressor after passing through the downstream portion of the evaporator. The refrigeration system may be configured to cool an appliance such as a refrigerator and/or freezer, or it may be utilized in air conditioners for buildings, motor vehicles, or other such spaces.

  12. Bounded stabilisation of stochastic port-Hamiltonian systems

    NASA Astrophysics Data System (ADS)

    Satoh, Satoshi; Saeki, Masami

    2014-08-01

    This paper proposes a stochastic bounded stabilisation method for a class of stochastic port-Hamiltonian systems. Both full-actuated and underactuated mechanical systems in the presence of noise are considered in this class. The proposed method gives conditions for the controller gain and design parameters under which the state remains bounded in probability. The bounded region and achieving probability are both assignable, and a stochastic Lyapunov function is explicitly provided based on a Hamiltonian structure. Although many conventional stabilisation methods assume that the noise vanishes at the origin, the proposed method is applicable to systems under persistent disturbances.

  13. PORT II

    NASA Technical Reports Server (NTRS)

    Muniz, Beau

    2009-01-01

    One unique project that the Prototype lab worked on was PORT I (Post-landing Orion Recovery Test). PORT is designed to test and develop the system and components needed to recover the Orion capsule once it splashes down in the ocean. PORT II is designated as a follow up to PORT I that will utilize a mock up pressure vessel that is spatially compar able to the final Orion capsule.

  14. iPAS Propulsion Subsystem

    NASA Technical Reports Server (NTRS)

    Sanchez, Rodrigo

    2011-01-01

    The ultimate goal of the Integrated Power, Avionics and Software (iPAS) project is to develop a simulation facility that can be apply to various missions that use common avionics, hardware, and software architecture. The iPAS facility will model several subsystems, the EP4 contribution to the project is to design and build a low fidelity representation of the in-space propulsion system for the iPAS simulation. The system would use a pressurized bottle to provide the gas for the thrusters. Air will be used to perform the simulation to prevent a hazardous environment in the facility. Three cold gas thrusters previously used for the X-38 program will be used for the simulation because they are on hand and available for use. An incremental design-build-test approach will be taken where the X-38 thrusters may be replaced with actual flight thrusters as the flight design is matured. A pressurized system must be designed, built, and tested to reduce the 2,400psi bottle pressure to a reasonable pressure (0-800psig) to minimize the amount of noise created upon thruster activation. Once all the subsystems are completed they will be integrated together for testing.

  15. Sustainability and the Spanish port system. Analysis of the relationship between economic and environmental indicators.

    PubMed

    Laxe, Fernando González; Bermúdez, Federico Martín; Palmero, Federico Martín; Novo-Corti, Isabel

    2016-12-15

    Research into the methodological development of alternative systems of sustainability measures is recent. In understanding sustainable development in a multi-dimensional sense, one of the most significant advances was the construction of Synthetic Indexes, applicable to different spatial spheres or to organisations, businesses, institutions, etc. The Spanish port system of general interest comprises 46 ports integrated in 28 Port Authorities, which in 2014 moved 482,000,000t of goods and more than 28 million passengers. This gives an idea of its importance for the Spanish economy. Using a derivation of the procedure used to calculate the Port Sustainability Synthetic Index, in this research the analysis of the relationship that exists between the findings obtained for the economic and environmental dimensions is used. This enables the existence of links between ports and economic and environmental indicators for a sample of 16 Port Authorities of Spain to be verified.

  16. Complications of Transfemoral Removal of Percutaneous Transfemorally Implanted Port-Catheter Systems

    SciTech Connect

    Yahiro, Yoshiyuki; Toyota, Naoyuki Kakizawa, Hideaki; Hieda, Masashi; Hirai, Nobuhiko; Naito, Akira; Ito, Katsuhide

    2006-10-15

    Our purpose is to evaluate the feasibility and safety of the withdrawal procedure of percutaneous transfemorally implanted port-catheter systems. Thirty-seven patients (17.7%) underwent the withdrawal procedure of this port-catheter system among 209 patients. The reasons for withdrawal were as follows: termination of intra-arterial chemotherapy (n = 7), obstruction of hepatic artery (n = 5), port infection (n = 4), catheter infection (n = 4), catheter obstruction (n = 4), lower-limb palsy and pain (n = 2), exposure of the port due to skin defect (n = 2), patient's desire (n = 2), side effect of chemotherapy (n = 1), no effectiveness of chemotherapy (n = 1), hematoma at the puncture site (n = 1), duodenum perforation by the catheter (n = 1), intermittent claudication due to severe stenosis of right common iliac artery (n = 1), dissection of common hepatic artery (n = 1), and broken catheter (n = 1). In thirty-four of the 37 cases, the port-catheter system was successfully withdrawn without any complications. Clinical success rate was 91.9%. Complications occurred in three cases (8.1%), which were a pseudoaneurysm, thromboembolism of the right common iliac artery, and continuous bleeding from the subcutaneous pocket where the port system was placed for 1 month. In 15 cases, correction of the catheter tip or exchange for dislocation of the tip had to be done without withdrawal. It is not rare to withdraw port-catheter systems in cases of infection or hematoma around the system. Although withdrawal of a percutaneous transfemorally implanted port-catheter system is a relatively safe procedure, the port-catheter system should not be removed unless absolutely indicated.

  17. A user-friendly automated port placement planning system for laparoscopic robotic surgery

    NASA Astrophysics Data System (ADS)

    Torres, Luis G.; Azimian, Hamidreza; Enquobahrie, Andinet

    2014-03-01

    Laparoscopic surgery is a minimally invasive surgical approach in which surgical instruments are passed through ports placed at small incisions. This approach can benefit patients by reducing recovery times and scars. Surgeons have gained greater dexterity, accuracy, and vision through adoption of robotic surgical systems. However, in some cases a preselected set of ports cannot be accommodated by the robot; the robot's arms may cause collisions during the procedure, or the surgical targets may not be reachable through the selected ports. In this case, the surgeon must either make more incisions for more ports, or even abandon the laparoscopic approach entirely. To assist in this, we are building an easytouse system which, given a surgical task and preoperative medical images of the patient, will recommend a suitable port placement plan for the robotic surgery. This work bears two main contributions: 1) a high level user interface that assists the surgeon in operating the complicated underlying planning algorithm; and 2) an interface to assist the surgical team in implementation of the recommended plan in the operating room. We believe that such an automated port placement system would reduce setup time for robotic surgery and reduce the morbidity to patients caused by unsuitable surgical port placement.

  18. Single-photon multi-ports router based on the coupled cavity optomechanical system.

    PubMed

    Li, Xun; Zhang, Wen-Zhao; Xiong, Biao; Zhou, Ling

    2016-12-22

    A scheme of single-photon multi-port router is put forward by coupling two optomechanical cavities with waveguides. It is shown that the coupled two optomechanical cavities can exhibit photon blockade effect, which is generated from interference of three mode interaction. A single-photon travel along the system is calculated. The results show that the single photon can be controlled in the multi-port system because of the radiation pressure, which should be useful for constructing quantum network.

  19. Ceci N'est Pas a globular cluster: the metallicity distribution of the stellar system Terzan 5

    SciTech Connect

    Massari, D.; Mucciarelli, A.; Ferraro, F. R.; Lanzoni, B.; Dalessandro, E.; Lovisi, L.; Rich, R. M.; Reitzel, D.; Valenti, E.; Ibata, R.

    2014-11-01

    We present new determinations of the iron abundance for 220 stars belonging to the stellar system Terzan 5 in the Galactic bulge. The spectra have been acquired with FLAMES at the Very Large Telescope of the European Southern Observatory and DEIMOS at the Keck II Telescope. This is by far the largest spectroscopic sample of stars ever observed in this stellar system. From this data set, a subsample of targets with spectra unaffected by TiO bands was extracted and statistically decontaminated from field stars. Once combined with 34 additional stars previously published by our group, a total sample of 135 member stars covering the entire radial extent of the system has been used to determine the metallicity distribution function of Terzan 5. The iron distribution clearly shows three peaks: a super-solar component at [Fe/H] ≅ 0.25 dex, accounting for ∼29% of the sample, a dominant sub-solar population at [Fe/H] ≅ –0.30 dex, corresponding to ∼62% of the total, and a minor (6%) metal-poor component at [Fe/H] ≅ –0.8 dex. Such a broad, multi-modal metallicity distribution demonstrates that Terzan 5 is not a genuine globular cluster but the remnant of a much more complex stellar system.

  20. Continued growth for military PAs.

    PubMed

    Salyer, Steven W

    2002-10-01

    The US military physician assistant (PA) originated from the corpsmen and medics of the army, navy, air force, and Coast Guard. PAs have been present in every military campaign since 1980 and serve in a wide variety of medical roles. Their combat role has expanded so that in many instances the PA has replaced the physician as the front-line care provider. All have moved from warrant officer into the commissioned officer ranks, a change that has enabled them to rise into command and administrative positions. Narrowing of the pay differential between military and civilian PAs has contributed to their retention.

  1. Single-photon multi-ports router based on the coupled cavity optomechanical system

    PubMed Central

    Li, Xun; Zhang, Wen-Zhao; Xiong, Biao; Zhou, Ling

    2016-01-01

    A scheme of single-photon multi-port router is put forward by coupling two optomechanical cavities with waveguides. It is shown that the coupled two optomechanical cavities can exhibit photon blockade effect, which is generated from interference of three mode interaction. A single-photon travel along the system is calculated. The results show that the single photon can be controlled in the multi-port system because of the radiation pressure, which should be useful for constructing quantum network. PMID:28004773

  2. Infection of an intravenous port system with Metschnikowia pulcherrima Pitt et Miller.

    PubMed

    Mohl, W; Lerch, M M; Klotz, M; Freidank, H; Zeitz, M

    1998-11-01

    A patient with short bowel syndrome as a consequence of multiple intestinal resections for Crohn's disease, had a port system implanted to improve her nutritional status. One year later she presented with fever, weakness and nighttime sweating. Metschnikowia pulcherrima Pitt et Miller was grown in blood cultures from the port system. After antifungal chemotherapy using fluconazole and removal of the implant, the patient's condition improved markedly and her fever and sweating disappeared. We conclude that Metschnikowia pulcherrima can turn into a human pathogen in patients with indwelling catheters for parenteral nutrition. Chemotherapy with fluconazole and, whenever possible, removal of the implant, appear to be adequate treatment.

  3. A Multi-Agent System for Tracking the Intent of Surface Contacts in Ports and Waterways

    DTIC Science & Technology

    2005-03-01

    identify asymmetric maritime threats in port and waterways. Each surface track is monitored by a compound multi - agent system that comprise of the several...intent models, each containing a nested multi - agent system . The attributes that define intent models of friendly, neutral, unknown and potentially

  4. Functional description for the Worldwide Port System (WPS) Regional Integrated Cargo Database (ICDB)

    SciTech Connect

    Truett, L.F.; Rollow, J.P.; Shipe, P.C.; Faby, E.Z.; Fluker, J.; Hancock, W.R.; Grubb, J.W.; Russell, D.L.; Ferguson, R.A.

    1995-12-15

    This Functional Description for the Worldwide Port System (WPS) Regional Integrated Cargo Database (ICDB) documents the purpose of and requirements for the ICDB in order to ensure a mutual understanding between the development group and the user group of the system. This Functional Description defines ICDB and provides a clear statement of the initial operational capability to be developed.

  5. Database specification for the Worldwide Port System (WPS) Regional Integrated Cargo Database (ICDB)

    SciTech Connect

    Faby, E.Z.; Fluker, J.; Hancock, B.R.; Grubb, J.W.; Russell, D.L.; Loftis, J.P.; Shipe, P.C.; Truett, L.F.

    1994-03-01

    This Database Specification for the Worldwide Port System (WPS) Regional Integrated Cargo Database (ICDB) describes the database organization and storage allocation, provides the detailed data model of the logical and physical designs, and provides information for the construction of parts of the database such as tables, data elements, and associated dictionaries and diagrams.

  6. 77 FR 44472 - Safety Zone; Port Valdez, Alaska Maritime Highway System Ferry Terminal

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-30

    ... Ferry Terminal AGENCY: Coast Guard, DHS. ] ACTION: Temporary final rule. SUMMARY: The Coast Guard is... Marine Highway System (AMHS) Terminal in Port Valdez when an AMHS Ferry is arriving or departing when... AMHS Ferry Terminal. This safety zone is necessary to provide for the safety of passenger vessels...

  7. Environmental Factors' Consideration at Industrial Transportation Organization in the «Seaport - Dry port» System

    NASA Astrophysics Data System (ADS)

    Muravev, Dmitri; Rakhmangulov, Aleksandr

    2016-11-01

    Currently, container shipping development is directly associated with an increase of warehouse areas for containers' storage. One of the most successful types of container terminal is an intermodal terminal called a dry port. Main pollution sources during the organization of intermodal transport are considered. A system of dry port parameters, which are recommended for the evaluation of different scenarios for a seaport infrastructure development at the stage of its strategic planning, is proposed in this paper. The authors have developed a method for determining the optimal values of the main dry port parameters by simulation modeling in the programming software Any- Logic. Dependencies thatwere obtained as a result of modeling experiments prove the adequacy of main selected dry port parameters for the effective scenarios' evaluation of throughput and handling capacity at existing seaports at the stage of strategic planning and a rational dry port location, allowed ensuring the improvement of the ecological situation in a port city.

  8. Ford Partnership for Advanced Studies (Ford PAS)

    ERIC Educational Resources Information Center

    Carrier, Cheryl

    2006-01-01

    This article features the Ford Partnership for Advanced Studies (Ford PAS) program that helps students gain knowledge about real-life business issues. Ford PAS is an educational program that combines college-prep academics with the critical 21st century skills students will need to succeed in college and in the workplace. The Ford PAS program uses…

  9. Test Report for Cricket Radiation Detection System Used In EPA Port Installations

    SciTech Connect

    Shourbaji, AA

    2004-08-11

    Oak Ridge National Laboratory conducted field radiological measurements at two port locations at the request of the Environmental Protection Agency (EPA). The radiological measurements were performed on five radiation detection systems at the port of Darrow, Louisiana and three systems at the port of Charleston, South Carolina. Darrow was visited on January 20-23, 2004 and Charleston on May 25, 2004. All tested systems are designed to detect radioactive material that might be present in scrap metals as the scrap is being unloaded from ships. All eight systems are commercially known as the Cricket and manufactured by RAD/COMM Systems. Each radiation detection system consists of a detector with two channels and a wireless transmitter, both mounted on the grapple, and a controller located in the crane cab. The cranes at both locations are operated by the Cooper T. Smith Company. The purpose of the radiological measurements was to evaluate the performance of the radiation detection systems in terms of their ability to detect elevated radiation levels, and to develop a routine testing method for all EPA Cricket systems.

  10. System/subsystem specifications for the Worldwide Port System (WPS) Regional Integrated Cargo Database (ICDB)

    SciTech Connect

    Rollow, J.P.; Shipe, P.C.; Truett, L.F.; Faby, E.Z.; Fluker, J.; Grubb, J.; Hancock, B.R.; Ferguson, R.A.

    1995-11-20

    A system is being developed by the Military Traffic Management Command (MTMC) to provide data integration and worldwide management and tracking of surface cargo movements. The Integrated Cargo Database (ICDB) will be a data repository for the WPS terminal-level system, will be a primary source of queries and cargo traffic reports, will receive data from and provide data to other MTMC and non-MTMC systems, will provide capabilities for processing Advance Transportation Control and Movement Documents (ATCMDs), and will process and distribute manifests. This System/Subsystem Specifications for the Worldwide Port System Regional ICDB documents the system/subsystem functions, provides details of the system/subsystem analysis in order to provide a communication link between developers and operational personnel, and identifies interfaces with other systems and subsystems. It must be noted that this report is being produced near the end of the initial development phase of ICDB, while formal software testing is being done. Following the initial implementation of the ICDB system, maintenance contractors will be in charge of making changes and enhancing software modules. Formal testing and user reviews may indicate the need for additional software units or changes to existing ones. This report describes the software units that are components of this ICDB system as of August 1995.

  11. Design of a dual port volume measuring system

    SciTech Connect

    Klevgard, P.A.

    1990-09-01

    A volume measuring system is described which uses the ideal gas law and pressure measurements to determine an unknown vessel's volume when a gas expands into that vessel from a known volume. The design, the engineering principles, the calibration, and the accuracy of this computer-controlled system are all discussed. A set of electrical and mechanical drawings of the system is included. 3 refs., 6 figs.

  12. Kinetic characterization of the WalRKSpn (VicRK) two-component system of Streptococcus pneumoniae: dependence of WalKSpn (VicK) phosphatase activity on its PAS domain.

    PubMed

    Gutu, Alina D; Wayne, Kyle J; Sham, Lok-To; Winkler, Malcolm E

    2010-05-01

    The WalRK two-component system plays important roles in maintaining cell wall homeostasis and responding to antibiotic stress in low-GC Gram-positive bacteria. In the major human pathogen, Streptococcus pneumoniae, phosphorylated WalR(Spn) (VicR) response regulator positively controls the transcription of genes encoding the essential PcsB division protein and surface virulence factors. WalR(Spn) is phosphorylated by the WalK(Spn) (VicK) histidine kinase. Little is known about the signals sensed by WalK histidine kinases. To gain information about WalK(Spn) signal transduction, we performed a kinetic characterization of the WalRK(Spn) autophosphorylation, phosphoryltransferase, and phosphatase reactions. We were unable to purify soluble full-length WalK(Spn). Consequently, these analyses were performed using two truncated versions of WalK(Spn) lacking its single transmembrane domain. The longer version (Delta35 amino acids) contained most of the HAMP domain and the PAS, DHp, and CA domains, whereas the shorter version (Delta195 amino acids) contained only the DHp and CA domains. The autophosphorylation kinetic parameters of Delta35 and Delta195 WalK(Spn) were similar [K(m)(ATP) approximately 37 microM; k(cat) approximately 0.10 min(-1)] and typical of those of other histidine kinases. The catalytic efficiency of the two versions of WalK(Spn) approximately P were also similar in the phosphoryltransfer reaction to full-length WalR(Spn). In contrast, absence of the HAMP-PAS domains significantly diminished the phosphatase activity of WalK(Spn) for WalR(Spn) approximately P. Deletion and point mutations confirmed that optimal WalK(Spn) phosphatase activity depended on the PAS domain as well as residues in the DHp domain. In addition, these WalK(Spn) DHp domain and DeltaPAS mutations led to attenuation of virulence in a murine pneumonia model.

  13. Minimally Invasive Lumbar Port System for the Collection of Cerebrospinal Fluid from Rhesus Macaques (Macaca mulatta).

    PubMed

    MacAllister, Rhonda Pung; Lester McCully, Cynthia M; Bacher, John; Thomas Iii, Marvin L; Cruz, Rafael; Wangari, Solomon; Warren, Katherine E

    2016-01-01

    Biomedical translational research frequently incorporates collection of CSF from NHP, because CSF drug levels are used as a surrogate for CNS tissue penetration in pharmacokinetic and dynamic studies. Surgical placement of a CNS ventricular catheter reservoir for CSF collection is an intensive model to create and maintain and thus may not be feasible or practical for short-term studies. Furthermore, previous NHP lumbar port models require laminectomy for catheter placement. The new model uses a minimally invasive technique for percutaneous placement of a lumbar catheter to create a closed, subcutaneous system for effective, repeated CSF sample collection. None of the rhesus macaques (Macaca mulatta; n = 10) implanted with our minimally invasive lumbar port (MILP) system experienced neurologic deficits, postoperative infection of the surgical site, or skin erosion around the port throughout the 21.7-mo study. Functional MILP systems were maintained in 70% of the macaques, with multiple, high-quality, 0.5- to 1.0-mL samples of CSF collected for an average of 3 mo by using aspiration or gravitational flow. Among these macaques, 57% had continuous functionality for a mean of 19.2 mo; 50% of the cohort required surgical repair for port repositioning and replacement during the study. The MILP was unsuccessful in 2 macaques, at an average of 9.5 d after surgery. Nonpatency in these animals was attributed to the position of the lumbar catheter. The MILP system is an appropriate replacement for temporary catheterization and previous models requiring laminectomy and is a short-term alternative for ventricular CSF collection systems in NHP.

  14. Small estuary, big port - progress in the management of the Stour-Orwell Estuary system

    NASA Astrophysics Data System (ADS)

    Spearman, Jeremy; Baugh, John; Feates, Nigel; Dearnaley, Mike; Eccles, Dan

    2014-10-01

    Management of port development is increasingly challenging because of the competitive requirement for deeper channels and because of the need to preserve important coastal wetlands which function as both habitat and flood defence. This paper describes the management of the Stour/Orwell Estuary system, Eastern England, an estuary system which has experienced considerable development and morphological change. The estuary is internationally important for its wetland bird populations and the intertidal areas of the estuary system are protected under European legislation. It is also the location of the Port of Felixstowe. In 1998/2000 the approach channel to the Port of Felixstowe was deepened from -12.5 mCD to -14.5 mCD. This paper describes the effects of the approach channel deepening, the approach taken to identifying the potential impact to intertidal habitat resulting from the deepening, the sediment recycling implemented as mitigation to prevent increased loss of habitat and the subsequent response of the estuary system to this intervention.

  15. Modeling integrated urban water systems in developing countries: case study of Port Vila, Vanuatu.

    PubMed

    Poustie, Michael S; Deletic, Ana

    2014-12-01

    Developing countries struggle to provide adequate urban water services, failing to match infrastructure with urban expansion. Despite requiring an improved understanding of alternative infrastructure performance when considering future investments, integrated modeling of urban water systems is infrequent in developing contexts. This paper presents an integrated modeling methodology that can assist strategic planning processes, using Port Vila, Vanuatu, as a case study. 49 future model scenarios designed for the year 2050, developed through extensive stakeholder participation, were modeled with UVQ (Urban Volume and Quality). The results were contrasted with a 2015 model based on current infrastructure, climate, and water demand patterns. Analysis demonstrated that alternative water servicing approaches can reduce Port Vila's water demand by 35 %, stormwater generation by 38 %, and nutrient release by 80 % in comparison to providing no infrastructural development. This paper demonstrates that traditional centralized infrastructure will not solve the wastewater and stormwater challenges facing rapidly growing urban cities in developing countries.

  16. Extravehicular Activity (EVA) Power, Avionics, and Software (PAS) 101

    NASA Technical Reports Server (NTRS)

    Irimies, David

    2011-01-01

    EVA systems consist of a spacesuit or garment, a PLSS, a PAS system, and spacesuit interface hardware. The PAS system is responsible for providing power for the suit, communication of several types of data between the suit and other mission assets, avionics hardware to perform numerous data display and processing functions, and information systems that provide crewmembers data to perform their tasks with more autonomy and efficiency. Irimies discussed how technology development efforts have advanced the state-of-the-art in these areas and shared technology development challenges.

  17. JPCam: Status of the 1.2Gpixel camera for the J-PAS survey.

    NASA Astrophysics Data System (ADS)

    Taylor, Keith; Marín-Franch, Antonio; Santoro, Fernando; Mendes de Oliveira, Claudia; Dupke, Renato

    2015-08-01

    JPCam is a 14-CCD mosaic camera, using the new e2v 9k-by-9k, 10 micron pixel detectors, to be deployed on the JST/T250, a dedicated 2.55m wide-field telescope at the OAJ (Observatorio Astrofísico de Javalambre) in Teruel, Spain. The camera is designed to perform the J-PAS, a BAO survey of the northern sky. The J-PAS survey strategy will use 59 filters, 56 relatively narrow-band (14.5nm) filters equi-spaced between 350 and 1000nm plus 3 broad-band filters to achieve unprecedented photometric red-shift accuracies for faint galaxies over 8000 square degrees of sky. The cryostat, detector mosaic and read electronics is being supplied by e2v. Each science detector is read from 16 ports simultaneously, allowing read times of 14s with a typical read noise of 5e- (rms). The JPCam focal plane will be complemented with 4 autoguiding and 8 wavefront sensing CCDs. Image quality over the whole CCD mosaic will be maintained by applying the required, close loop, focus, tilt and rotation adjustments to the focal plane through the JPCam hexapod actuator system, manufactured by NTE-Sener. The filter unit has been designed to admit 5 filter trays, each mounting 14 filters corresponding to the 14 CCDs of the mosaic. Each CCD will view only its corresponding filter avoiding optical cross-talk from their neighbors. With this configuration, JPCam will cover 4.7 square degrees with a plate scale of 0.2267 arcsec/pix and will allow all the J-PAS filters to be permanently installed on the camera. The massive 525mm aperture shutter is supplied by Bonn-Shutter UG.

  18. Earth Port-Moon Port design

    NASA Technical Reports Server (NTRS)

    1987-01-01

    A pair of compatible transfer stations or Space Ports and associated transfer vehicles was designed in order to support permanent manned lunar facilities. One of the Space Ports was placed in earth orbit (not necessarily Low Earth Orbit - LEO), and the other in lunar orbit. The primary purposes of the Space Ports was to support the lunar surface facility, the return of lunar manufactured items to the earth, and the transfer of lunar manufactured items to space vehicles and earth orbital space stations. The design was constrained by the following: (1) The orbital altitudes and inclinations of the Earth Port and Moon Port were chosen to minimize the overall cost of transporting materials to and from the moon. The ETO (Earth-to-Orbit) costs were considered separately to allow consideration of initiating planetary missions, etc., from the Earth Port. (2) A new earth launch point was chosen to facilitate the support of the lunar facility. This launch point was chosen to minimize overall costs, maximize overall safety, and to avoid political problems. To this end, it was mandatory the launch site be owned by the United States or one of its close allies. In addition, the launch would take place over water and expendable stages would drop into the ocean. Space shuttle type vehicles could be used if appropriate provisions were made for aborts, SRB and ET impact, etc. The ground track and impact point studies included space shuttle type vehicles, current ELV's (expendable launch vehicles, and HLLV's (heavy lift launch vehicles). (3) The Earth Port and Moon Port orbits were selected so that transfer trajectories between the two facilities could be initiated often without major plane change penalties. The amount of these penalties was calculated. Families of Earth Port to Moon Port and Moon Port to Earth Port trajectories were calculated to document the energy requirements and penalties. (4) Space Port module designs included module systems definitions, module masses, system

  19. A data-management system using sensor technology and wireless devices for port security

    NASA Astrophysics Data System (ADS)

    Saldaña, Manuel; Rivera, Javier; Oyola, Jose; Manian, Vidya

    2014-05-01

    Sensor technologies such as infrared sensors and hyperspectral imaging, video camera surveillance are proven to be viable in port security. Drawing from sources such as infrared sensor data, digital camera images and processed hyperspectral images, this article explores the implementation of a real-time data delivery system. In an effort to improve the manner in which anomaly detection data is delivered to interested parties in port security, this system explores how a client-server architecture can provide protected access to data, reports, and device status. Sensor data and hyperspectral image data will be kept in a monitored directory, where the system will link it to existing users in the database. Since this system will render processed hyperspectral images that are dynamically added to the server - which often occupy a large amount of space - the resolution of these images is trimmed down to around 1024×768 pixels. Changes that occur in any image or data modification that originates from any sensor will trigger a message to all users that have a relation with the aforementioned. These messages will be sent to the corresponding users through automatic email generation and through a push notification using Google Cloud Messaging for Android. Moreover, this paper presents the complete architecture for data reception from the sensors, processing, storage and discusses how users of this system such as port security personnel can use benefit from the use of this service to receive secure real-time notifications if their designated sensors have detected anomalies and/or have remote access to results from processed hyperspectral imagery relevant to their assigned posts.

  20. Stabilization of a Percutaneously Implanted Port Catheter System for Hepatic Artery Chemotherapy Infusion

    SciTech Connect

    Shindoh, Noboru; Ozaki, Yutaka; Kyogoku, Shinsuke; Yamana, Daigo; Sumi, Yukiharu; Katayama, Hitoshi

    1999-07-15

    A port catheter system for hepatic artery infusion chemotherapy was implanted percutaneously via the left subclavian artery in 41 patients for treatment of unresectable liver metastases. The catheter tip was inserted into the gastroduodenal artery (GDA), the end hole was occluded with a guidewire fragment, and a side-hole for infusion was positioned at the bifurcation of the proper hepatic artery and the GDA. The GDA was embolized with steel coils around the infusion catheter tip via a transfemoral catheter. This procedure is designed to reduce the incidence of hepatic artery occlusion and infusion catheter dislocation.

  1. Interventional Radiological Procedures in Impaired Function of Surgically Implanted Catheter-Port Systems

    SciTech Connect

    Herrmann, Karin Anna; Waggershauser, Tobias; Heinemann, Volker; Reiser, Maximilian

    2001-01-15

    Purpose: System-related complications in surgically implanted catheter-port systems (CPS) for intraarterial (i.a.) chemotherapy are well known. In most cases of complications, the treatment must be interrupted and the catheter-port system must be repaired surgically. We describe microinvasive interventional radiological procedures to correct some dysfunctions of CPS.Methods: Five patients with repetitive dysfunction of CPS were treated with interventional techniques. Two patients presented with perfusion impairment, one patient had a pseudoaneurysm of the hepatic artery, and two patients presented with catheter displacement. Radiological interventions included mechanical recanalization with a guidewire, vascular stenting, and correction of catheter dislocation with a goose-neck snare.Results: In all cases, correct function of the CPS was restored. No intervention-related complications occurred and surgery was avoided. Chemotherapy could be continued for a period of 4-10 months.Conclusion: For some system-related complications, minimally invasive radiological interventions can be used to restore the function of CPS for i.a. chemotherapy.

  2. The submarine river of Port Miou (France), A karstic system inherited from the Messinian deep stage

    NASA Astrophysics Data System (ADS)

    Cavalera, T.; Gilli, E.

    2009-04-01

    The Port Miou system (Cassis, France) is a two kilometers long submarine gallery that extends in the limestone series of Calanques (Marseille, France). The average discharge is between 2 to 5 m3/s but the water is brackish and cannot be used for water supply. In the 1970s, a dam was built to prevent saltwater intrusion in the cave but these experimental attempts did not succeed in getting rid of the residual salinity which remained near 3 g l-1 upstream the dam. The use of helium and later rebreathers by cave divers made possible the exploration of a vertical pit down to 179 m below the sea level. At that depth, the water is still brackish. The cave extends further and deeper but the exploration is limited by the present diving technology. The canyon of Cassidaigne is located a few kilometers south from Port Miou. It cuts the continental shelf where bathymetric studies have shown the presence of dolines. Caves and speleothems have been observed during submarine explorations on the walls of the canyon. This canyon is not connected to a continental valley and it is assumed that it is a pocket valley. Its presence is related to the several lowering stages of the Mediterranean Sea during the Messinian Salinity Crisis. We suggest that during the important drop of sea level of the Mediterranean, the underground river of Port-Miou, flowed several hundreds meters below its current position, and excavated the canyon. At the end of the Messinian crisis, the system was flooded by seawater. The karst water now flows through an upper gallery but the presence of a paleo-drain filled by seawater makes possible a deep marine intrusion into the karst system. Several geomorphologic clues (bathymetry, submarine valley network…) reinforce the fact that the continental shelf near Marseilles is an important karstic network drowned below the sea level. This model is supported by the observation in Port Miou of an important quantity of titanium at the upper surface of the cave sediment

  3. A system dynamics approach to intermodalism at the Port of Lewiston

    SciTech Connect

    Sebo, D.

    1996-08-01

    Intermodalism refers to interconnections among modes of transportation, e.g., road, rail, water, and air. Effective intermodal planning must cross boundaries between the public and private sectors as well as transportation modes. The development of an effective and efficient intermodal transportation system requires the identification of barriers to intermodal transportation and the investigation of the impact of proposed changes in infrastructure development, policies, regulations, and planning. A systems approach is necessary to adequately represent the interaction between the sometimes incompatible concerns of all modes and stakeholders. A systems dynamics model of intermodalism at the Port of Lewiston has been developed to highlight leverage points, hidden assumptions, second order effects resulting from feedback loops and system drivers. The purpose of this document is to present the results of the system dynamics model work.

  4. Design plan for development of the worldwide port system (WPS) regional integrated cargo database (ICDB)

    SciTech Connect

    Truett, L.F.; Rollow, J.P.; Shipe, P.C.

    1995-11-01

    The Worldwide Port System (WPS) Regional Integrated Cargo Database (ICDB) is a major military computer system that provides visibility over international cargo. Development started in early 1993 and implementation began on the West Coast in August of 1995. The Design Plan coordinated developmental efforts for the ICDB and its related processes. A Design Plan was especially important because the ICDB was developed at multiple sites by Oak Ridge National Laboratory and Military Traffic Management Command personnel. A Design Plan was essential to ensure that a consistent design was maintained throughout all modules, that functional and technical requirements were accomplished, that all components and processes worked together successfully, and that the development schedule was met. This plan described ICDB modules and tasks within each module. It documented responsibilities and dependencies by module and presented a schedule for development, testing, and integration.

  5. Multi-port power router and its impact on resilient power grid systems

    NASA Astrophysics Data System (ADS)

    Kado, Yuichi; Iwatsuki, Katsumi; Wada, Keiji

    2016-02-01

    We propose a Y-configuration power router as a unit cell to easily construct a power delivery system that can meet many types of user requirements. The Y-configuration power router controls the direction and magnitude of power flow among three ports regardless of DC and AC. We constructed a prototype three-way isolated DC/DC converter that is the core unit of the Y-configuration power router and tested the power flow control operation. Experimental results revealed that our methodology based on the governing equation was appropriate for the power flow control of the three-way DC/DC converter. In addition, the hexagonal distribution network composed of the power routers has the ability to easily interchange electric power between autonomous microgrid cells. We also explored the requirements for communication between energy routers to achieve dynamic adjustments of energy flow in a coordinated manner and its impact on resilient power grid systems.

  6. Case report: treatment of subdural hematoma in the emergency department utilizing the subdural evacuating port system.

    PubMed

    Asfora, Wilson T; Klapper, Hendrik B

    2013-08-01

    Patients with acute or chronic subdural hematomas may present with rapidly deteriorating neurological function and are at risk for irreversible brainstem injury. In such cases, rapid surgical intervention is required to evacuate the hematoma and reverse critically elevated intracranial pressure. A variety of surgical drainage methods are in existence, none of which are clearly superior to the others. This report presents the case of a 74-year-old woman who suffered an acute-on-chronic subdural hematoma which was evacuated in the emergency department utilizing the subdural evacuating port system (SEPS). The SEPS provides for a minimally invasive technique to drain subdural hematomas and is advantageous in that it can be performed at the bedside. The SEPS is relatively simple to use and may be especially useful to emergency department staff in outlying areas where there is a shortage of neurosurgical coverage.

  7. EPA's Sustainable Port Communities: a Knowledge System Approach to Increasing Resiliency

    EPA Science Inventory

    Create a Sustainability Assessment Toolbox for US ports that: • Addresses multiple issues faced by ports • Builds on work from other EPA Research Programs • Complements other resiliency work from federal and NGO partners, e.g.: EPA’s Office of Transportat...

  8. A Community-Scale Modeling System to Assess Port-Related Air Quality Impacts

    EPA Science Inventory

    Near-port air pollution has been identified by numerous organizations as a potential public health concern. Based upon multiple near-road and near-source monitoring studies, both busy roadways and large emission sources at the ports may impact local air quality within several hun...

  9. Photodynamic therapy for port wine stains assisted by a novel robotic system

    NASA Astrophysics Data System (ADS)

    Huang, Naiyan; Zhu, Jianguo; Wang, Ying; Bian, Guibin; Duan, Xingguang; Liu, Weifeng; Tang, Xiaoying; Wang, Xingtao; Cui, Shihu; Zhang, Chunyu; Gu, Ying

    2010-11-01

    Port wine stains (PWS) is a vascular malformation consisting of dilated capillaries in the superficial dermis. Photodynamic therapy (PDT) is an effective approach in the treatment of PWS. However, the procedure of treatment is a low efficient and hard work, as the doctor need to hold laser fiber to irradiate for 20 min to 50 min per lesion. So an assisted novel robotic system was developed to instead part of doctor's work. The robotic system consisted of 7 degrees of freedom, in which there were 5 passive joints and 2 active joints. Binocular surveillance system was used as guidance for the robot. Clinical trial compared 20 patients (38 lesions) treated by the robotic system with another 20 patients (38 lesions) treated by a doctor. The patients in both groups were injected intravenously with photosensitizer (PSD-007, 4-5mg/kg) and irradiated with 532 nm laser (100mW/cm2, 120-300J/cm2) immediately. Both groups had same good therapeutic results. The robotic system is helpful in the PWS-PDT and hopefully would become a part of PWS therapy machine in the future.

  10. Standards and conventions for the Worldwide Port System (WPS) regional Integrated Cargo Database (ICDB)

    SciTech Connect

    Loftis, J.P.; Truett, L.F.; Shipe, P.C.; Faby, E.Z.; Fluker, J.; Grubb, J.W.; Hancock, B.R.; Ferguson, R.A.

    1995-02-28

    This document, prepared for the Worldwide Port System (WPS) Regional Integrated Cargo Database (ICDB), provides standards and conventions for the screens developed using ORACLE`s SQL*Menu, SQL*Forms, and SQL*Reportwriter; for the ORACLE keys; and for commenting ORACLE code. It also covers standards for database system transfers. The results of adherence to these standards and conventions by all developers at both geographically separated development sites, Oak Ridge National Laboratory (ORNL) and The Military Traffic Management Command`s Eastern Area (EA), will be a consistent appearance of ICDB to users, code that is easily maintained, and a system that will be quicker to develop and integrate. This final report of the Standards and Conventions contains general guidelines to be followed for the development of the ICDB user interface screens. Though additional ICDB user interface screens are being developed both at ORNL and EA, and existing screens may have fields added to or deleted from them, the standards and conventions presented in this document should remain unchanged.

  11. Intake port

    DOEpatents

    Mendler, Edward Charles

    2005-02-01

    The volumetric efficiency and power of internal combustion engines is improved with an intake port having an intake nozzle, a venturi, and a surge chamber. The venturi is located almost halfway upstream the intake port between the intake valves and the intake plenum enabling the venturi throat diameter to be exceptionally small for providing an exceptionally high ram velocity and an exceptionally long and in turn high efficiency diffuser flowing into the surge chamber. The intake port includes an exceptionally large surge chamber volume for blow down of the intake air into the working cylinder of the engine.

  12. Ports Initiative

    EPA Pesticide Factsheets

    The purpose of the ports initiative is to assist EPA and other participants to formulate strategies for moving forward on actions addressing the transportation, air quality and climate issues raised in the National Conversations.

  13. Ascaris and Escherichia coli Inactivation in an Ecological Sanitation System in Port-au-Prince, Haiti

    PubMed Central

    Berendes, David; Levy, Karen; Knee, Jackie; Handzel, Thomas; Hill, Vincent R.

    2015-01-01

    The goal of this study was to evaluate the microbial die-off in a latrine waste composting system in Port-au-Prince, Haiti. Temperature data and samples were collected from compost aged 0 – 12+ months. Samples collected from compost bin centers and corners at two depths were assessed for moisture content, E. coli concentration, and Ascaris spp. viability. Center temperatures in compost bins were all above 58 °C, while corner temperatures were 10 – 20 °C lower. Moisture content was 67 ± 10% in all except the oldest compost. A 4-log reduction in E. coli was observed over the first sixteen weeks of composting at both locations and depths, after which E. coli was undetectable (LOD: 142 MPN g-1 dry weight). In new compost, 10.4% and 8.3% of Ascaris eggs were viable and fully embryonated, respectively. Percent viability dropped to zero in samples older than six weeks. These findings indicate that the Haitian EcoSan composting process was effective in inactivating E. coli and Ascaris spp. in latrine waste within sixteen weeks. This study is one of the first to document efficacy of an ecological sanitation system under field conditions and provides insight into composting methods and monitoring for other international settings. PMID:25932948

  14. A Medical Manipulator System with Lasers in Photodynamic Therapy of Port Wine Stains

    PubMed Central

    Wang, Xingtao; Tian, Chunlai; Duan, Xingguang; Gu, Ying; Huang, Naiyan

    2014-01-01

    Port wine stains (PWS) are a congenital malformation and dilation of the superficial dermal capillary. Photodynamic therapy (PDT) with lasers is an effective treatment of PWS with good results. However, because the laser density is uneven and nonuniform, the treatment is carried out manually by a doctor thus providing little accuracy. Additionally, since the treatment of a single lesion can take between 30 and 60 minutes, the doctor can become fatigued after only a few applications. To assist the medical staff with this treatment method, a medical manipulator system (MMS) was built to operate the lasers. The manipulator holds the laser fiber and, using a combination of active and passive joints, the fiber can be operated automatically. In addition to the control input from the doctor over a human-computer interface, information from a binocular vision system is used to guide and supervise the operation. Clinical results are compared in nonparametric values between treatments with and without the use of the MMS. The MMS, which can significantly reduce the workload of doctors and improve the uniformity of laser irradiation, was safely and helpfully applied in PDT treatment of PWS with good therapeutic results. PMID:25302297

  15. Ascaris and Escherichia coli Inactivation in an Ecological Sanitation System in Port-au-Prince, Haiti.

    PubMed

    Berendes, David; Levy, Karen; Knee, Jackie; Handzel, Thomas; Hill, Vincent R

    2015-01-01

    The goal of this study was to evaluate the microbial die-off in a latrine waste composting system in Port-au-Prince, Haiti. Temperature data and samples were collected from compost aged 0-12+ months. Samples collected from compost bin centers and corners at two depths were assessed for moisture content, E. coli concentration, and Ascaris spp. viability. Center temperatures in compost bins were all above 58 °C, while corner temperatures were 10 - 20 °C lower. Moisture content was 67 ± 10% in all except the oldest compost. A 4-log reduction in E. coli was observed over the first sixteen weeks of composting at both locations and depths, after which E. coli was undetectable (LOD: 142 MPN g(-1) dry weight). In new compost, 10.4% and 8.3% of Ascaris eggs were viable and fully embryonated, respectively. Percent viability dropped to zero in samples older than six weeks. These findings indicate that the Haitian EcoSan composting process was effective in inactivating E. coli and Ascaris spp. in latrine waste within sixteen weeks. This study is one of the first to document efficacy of an ecological sanitation system under field conditions and provides insight into composting methods and monitoring for other international settings.

  16. Reductive evolution and the loss of PDC/PAS domains from the genus Staphylococcus

    PubMed Central

    2013-01-01

    Background The Per-Arnt-Sim (PAS) domain represents a ubiquitous structural fold that is involved in bacterial sensing and adaptation systems, including several virulence related functions. Although PAS domains and the subclass of PhoQ-DcuS-CitA (PDC) domains have a common structure, there is limited amino acid sequence similarity. To gain greater insight into the evolution of PDC/PAS domains present in the bacterial kingdom and staphylococci in specific, the PDC/PAS domains from the genomic sequences of 48 bacteria, representing 5 phyla, were identified using the sensitive search method based on HMM-to-HMM comparisons (HHblits). Results A total of 1,007 PAS domains and 686 PDC domains distributed over 1,174 proteins were identified. For 28 Gram-positive bacteria, the distribution, organization, and molecular evolution of PDC/PAS domains were analyzed in greater detail, with a special emphasis on the genus Staphylococcus. Compared to other bacteria the staphylococci have relatively fewer proteins (6–9) containing PDC/PAS domains. As a general rule, the staphylococcal genomes examined in this study contain a core group of seven PDC/PAS domain-containing proteins consisting of WalK, SrrB, PhoR, ArlS, HssS, NreB, and GdpP. The exceptions to this rule are: 1) S. saprophyticus lacks the core NreB protein; 2) S. carnosus has two additional PAS domain containing proteins; 3) S. epidermidis, S. aureus, and S. pseudintermedius have an additional protein with two PDC domains that is predicted to code for a sensor histidine kinase; 4) S. lugdunensis has an additional PDC containing protein predicted to be a sensor histidine kinase. Conclusions This comprehensive analysis demonstrates that variation in PDC/PAS domains among bacteria has limited correlations to the genome size or pathogenicity; however, our analysis established that bacteria having a motile phase in their life cycle have significantly more PDC/PAS-containing proteins. In addition, our analysis revealed a

  17. Three-dimensional transient numerical simulation for intake process in the engine intake port-valve-cylinder system.

    PubMed

    Luo, Ma-Ji; Chen, Guo-Hua; Ma, Yuan-Hao

    2003-01-01

    This paper presents a KIVA-3 code based numerical model for three-dimensional transient intake flow in the intake port-valve-cylinder system of internal combustion engine using body-fitted technique, which can be used in numerical study on internal combustion engine with vertical and inclined valves, and has higher calculation precision. A numerical simulation (on the intake process of a two-valve engine with a semi-sphere combustion chamber and a radial intake port) is provided for analysis of the velocity field and pressure field of different plane at different crank angles. The results revealed the formation of the tumble motion, the evolution of flow field parameters and the variation of tumble ratios as important information for the design of engine intake system.

  18. Hepatic perfusion abnormalities during treatment with hepatic arterial infusion chemotherapy: Value of CT arteriography using an implantable port system

    SciTech Connect

    Seki, Hiroshi; Kimura, Motomasa; Kamura, Takeshi; Miura, Tsutomu

    1996-05-01

    The purpose of this study was to evaluate CT arteriography (CTA) using an implantable port system in the detection of perfusion abnormalities occurring during hepatic arterial infusion chemotherapy (HAIC). In 51 patients with unresectable primary and metastatic liver tumors, who had implanted port systems for HAIC, CTA examinations through the infusion pump were performed. When perfusion abnormalities were found, selective angiography and/or digital subtraction angiography using the implantable port system were performed to determine the etiology. Forty-nine perfusion abnormalities were detected in 32 patients. Intrahepatic hypoperfusion was found in 24 cases. Of 11 patients in whom correction of the hypoperfusion was attempted, it was successful in 10. Of 13 patients in whom correction was not attempted, 6 patients showed progressive disease in nonperfused areas. Intrahepatic hyperperfusion was found in 14 cases, which showed no subsequent complication. Extrahepatic perfusion was found in 11 cases. We consider CTA to be useful in detecting perfusion abnormalities that may compromise HAIC. 22 refs., 3 figs., 3 tabs.

  19. ITER Port Interspace Pressure Calculations

    SciTech Connect

    Carbajo, Juan J; Van Hove, Walter A

    2016-01-01

    The ITER Vacuum Vessel (VV) is equipped with 54 access ports. Each of these ports has an opening in the bioshield that communicates with a dedicated port cell. During Tokamak operation, the bioshield opening must be closed with a concrete plug to shield the radiation coming from the plasma. This port plug separates the port cell into a Port Interspace (between VV closure lid and Port Plug) on the inner side and the Port Cell on the outer side. This paper presents calculations of pressures and temperatures in the ITER (Ref. 1) Port Interspace after a double-ended guillotine break (DEGB) of a pipe of the Tokamak Cooling Water System (TCWS) with high temperature water. It is assumed that this DEGB occurs during the worst possible conditions, which are during water baking operation, with water at a temperature of 523 K (250 C) and at a pressure of 4.4 MPa. These conditions are more severe than during normal Tokamak operation, with the water at 398 K (125 C) and 2 MPa. Two computer codes are employed in these calculations: RELAP5-3D Version 4.2.1 (Ref. 2) to calculate the blowdown releases from the pipe break, and MELCOR, Version 1.8.6 (Ref. 3) to calculate the pressures and temperatures in the Port Interspace. A sensitivity study has been performed to optimize some flow areas.

  20. Ports Primer: 3.2 Port Governance

    EPA Pesticide Factsheets

    State and local governments are important players in port governance and in oversight of transportation projects that may affect ports. Private corporations may also play a role if they lease or own a terminal at a port.

  1. C-PORT: A Community-Scale Near-Source Air Quality System to Assess Port-Related Air Quality Impacts

    EPA Science Inventory

    With increasing activity in global trade, there has been increased activity in transportation by rail, road and ships to move cargo. Based upon multiple near-road and near-source monitoring studies, both busy roadways and large emission source at the ports may impact local air qu...

  2. Risk of infection due to medical interventions via central venous catheters or implantable venous access port systems at the middle port of a three-way cock: luer lock cap vs. luer access split septum system (Q-Syte)

    PubMed Central

    2014-01-01

    Background Many cancer patients receive a central venous catheter or port system prior to therapy to assure correct drug administration. Even appropriate hygienic intervention maintenance carries the risk of contaminating the middle port (C-port) of a three-way cock (TWC), a risk that increases with the number of medical interventions. Because of the complexity of the cleaning procedure with disconnection and reconnection of the standard luer lock cap (referred as “intervention”), we compared luer lock caps with a “closed access system” consisting of a luer access split septum system with regard to process optimization (work simplification, process time), efficiency (costs) and hygiene (patient safety). Methods For determination of process optimization the workflow of an intervention according to the usual practice and risks was depicted in a process diagram. For determining the actual process costs, we analyzed use of material and time parameters per intervention and used the process parameters for programming the process into a simulation run (n = 1000) to determine the process costs as well as their differences (ACTUAL vs. NOMINAL) within the framework of a discrete event simulation. Additionally cultures were carried out at the TWC C-ports to evaluate possible contamination. Results With the closed access system, the mean working time of 5.5 minutes could be reduced to 2.97 minutes. The results for average process costs (labour and material costs per use) were 3.92 € for luer lock caps and 2.55 € for the closed access system. The hypothesis test (2-sample t-test, CI 0.95, p-value<0.05) confirmed the significance of the result. In 50 reviewed samples (TWC’s), the contamination rate for the luer lock cap was 8% (4 out of 50 samples were positive), the contamination rate of the 50 samples with the closed access system was 0%. Possible hygienic risks (related to material, surroundings, staff handling) could be reduced by 65.38%. Conclusions In the

  3. Pressure Regulator With Internal Ejector Circulation Pump, Flow and Pressure Measurement Porting, and Fuel Cell System Integration Options

    NASA Technical Reports Server (NTRS)

    Vasquez, Arturo

    2011-01-01

    An advanced reactant pressure regulator with an internal ejector reactant circulation pump has been developed to support NASA's future fuel cell power systems needs. These needs include reliable and safe operation in variable-gravity environments, and for exploration activities with both manned and un manned vehicles. This product was developed for use in Proton Exchange Membrane Fuel Cell (PEMFC) power plant reactant circulation systems, but the design could also be applied to other fuel cell system types, (e.g., solid-oxide or alkaline) or for other gas pressure regulation and circulation needs. The regulator design includes porting for measurement of flow and pressure at key points in the system, and also includes several fuel cell system integration options. NASA has recognized ejectors as a viable alternative to mechanical pumps for use in spacecraft fuel cell power systems. The ejector motive force is provided by a variable, high-pressure supply gas that travels through the ejector s jet nozzle, whereby the pressure energy of the fluid stream is converted to kinetic energy in the gas jet. The ejector can produce circulation-to-consumption-flow ratios that are relatively high (2-3 times), and this phenomenon can potentially (with proper consideration of the remainder of the fuel cell system s design) be used to provide completely for reactant pre-humidification and product water removal in a fuel cell system. Specifically, a custom pressure regulator has been developed that includes: (1) an ejector reactant circulation pump (with interchangeable jet nozzles and mixer sections, gas-tight sliding and static seals in required locations, and internal fluid porting for pressure-sensing at the regulator's control elements) and (2) internal fluid porting to allow for flow rate and system pressure measurements. The fluid porting also allows for inclusion of purge, relief, and vacuum-breaker check valves on the regulator assembly. In addition, this regulator could also

  4. SeaPort-e Workshop

    DTIC Science & Technology

    2014-08-01

    aquilent.com 22 QUESTIONS?? 23 Back-up 24 Program Evolution Category SeaPort Original (2001 – 2004) SeaPort-Enhanced (2004...Function = Industry User Function External System Interfaces: Create Purchase Request (Navy ERP ) Receive CAR Data (FPDS-NG) Receive Award Documents (EDA) Receive Award Data (SPS)

  5. Airborne Pointing and Tracking Systems Open Port Design and Modification Analysis

    DTIC Science & Technology

    1976-04-01

    8217 l" ’ ’ i i i •——’■ »mmmm* > BPT - OPtN fORT - PLOTS Of MOOC 5HBPC5 OlSPinCEHENT CRSE 2 X3 HKl/STRROTNE FINITE ELEMENT MODEL...APT - OPEN PORT - PLOTS OF MOOC SMBPtS OlSPLRCEnENT CRSC 6 HRJ/STBROYNE FINITE ELEMENT «OOEL PROJECTION ON X2-X9 PLRNC CASE NO. 2...liliiBliiMWlMWg 1 APT - OPEN PORT - PLOTS OF MOOC SHAPES OlSPLHCENENT CASE 7 ^-^^4»’ X3 I1R1/STAR0VNE FINITE ELEMENT MODEL PROJECTION ON X3-XI PLANE

  6. EPAs Sustainable Port Communities: Using a Systems Approach to Assess How the Built and Natural Environment Together Affect Resilience Capacity

    EPA Science Inventory

    Port Communities Face Many Challenges: Climate change – Sea Level Rise, Extreme Events - “Assets” become vulnerabilities, nuisance flooding, changes in waste water and stormwater capacity, changes in near-shore ecology and water quality. Port Expansion - Incr...

  7. An Efficient Shared Adaptive Packet Loss Concealment Scheme through 1-Port Gateway System for Internet Telephony Service

    NASA Astrophysics Data System (ADS)

    Kim, Jinsul; Lee, Hyunwoo; Ryu, Won; Lee, Byungsun; Hahn, Minsoo

    In this letter, we propose a shared adaptive packet loss concealment scheme for the high quality guaranteed Internet telephony service which connects multiple users. In order to recover packet loss efficiently in the all-IP based convergence environment, we provide a robust signal recovery scheme which is based on the shared adaptive both-side information utilization. This scheme is provided according to the average magnitude variation across the frames and the pitch period replication on the 1-port gateway (G/W) system. The simulated performance demonstrates that the proposed scheme has the advantages of low processing times and high recovery rates in the all-IP based ubiquitous environment.

  8. A Systems Analysis View of the Vietnam War: 1965-1972. Volume 12. Construction and Port Operations in South Vietnam

    DTIC Science & Technology

    1975-02-01

    SYSTEMS ANALYSIS VIEW OF ThE VIETW VAR: 1965-972,, L/A Y _ONSTRUCTION AND -PORT 4ERATIO!NS I11.1 SOUTH VIETNAM, VOLUME 12 luj -a/1.7 editor 0•. Th C iae 𔃺...SVN Feb 68 118 1 3. OTHER SUPPORT CINCPAC Flagpole Items Feb 67 120 4K A Srste-ns Analysis View Of The Vietnam. W-ar: 1965-1972 UETRIODUCI. LO This...34We used a highly interesting item in your May Analysis Report as the basis for a note to the Secretary, which I’ve attached." (State Department, 28

  9. Nek2 siRNA therapy using a portal venous port-catheter system for liver metastasis in pancreatic cancer.

    PubMed

    Kokuryo, Toshio; Hibino, Shigeru; Suzuki, Kazushi; Watanabe, Katsutaka; Yokoyama, Yukihiro; Nagino, Masato; Senga, Takeshi; Hamaguchi, Michinari

    2016-09-01

    Nek2 (NIMA-related kinase 2) is a serine-threonine kinase and human homolog of the mitotic regulator NIMA of Aspergillus nidulan. We reported the efficiency of Nek2 siRNA in several cancer xenograft models using cholangiocarcinoma, breast cancer and colorectal cancer. Pancreatic cancer is difficult to treat due to its rapid progression and resistance to chemotherapy. Novel treatments are urgently required to improve survival in pancreatic cancer, and siRNA are a promising therapeutic option. However, finding an in vivo drug delivery system of siRNA remains a major problem for clinical application. In this study, the overexpression of Nek2 was identified in pancreatic cancer cell lines. Nek2 siRNA inhibited tumor growth in a subcutaneous xenograft mouse model of pancreatic cancer, prolonged the survival time in an intraperitoneal xenograft mouse model and efficiently prevented the progression of liver metastasis using a portal venous port-catheter system. Taken together, Nek2 is an effective therapeutic target in pancreatic cancer. An adequate delivery system is considered important in treating advanced pancreatic cancer, such as peritoneal dissemination and liver metastasis. Further investigations are required on the safety and side effects of the portal venous port-catheter system. We hope that Nek2 siRNA will be a novel therapeutic strategy for pancreatic cancer with liver metastasis and peritoneal dissemination.

  10. Light signaling mediated by PAS domain-containing proteins in Xanthomonas campestris pv. campestris.

    PubMed

    Mao, Daqing; Tao, Jun; Li, Chunxia; Luo, Chao; Zheng, Linlin; He, Chaozu

    2012-01-01

    Per-ARNT-Sim (PAS) domains are important signalling modules that possibly monitor changes in various stimuli such as light. For the majority of PAS domains that have been identified by sequence similarity, the biological function of the signalling pathways has not yet been experimentally investigated.Thirty-three PAS proteins were discovered in Xanthomonas campestris pv. campestris(Xcc) by genome/proteome analysis. Thirteen PAS proteins were identified as contributing to light signalling and Xcc growth, motility or virulence using molecular genetics and bioinformatics methods. The PAS domains played important roles in light signalling to regulate the growth, motility and virulence of Xcc. They might be regulated by not only light quality (wavelength)but also quantity (intensity) as potential light-signalling components. Evaluating the light wavelength, three light-signalling types of PAS proteins in Xcc were shown to be involved in blue light signalling, tricolour (blue, red and far red)signalling or red/far-red signalling. This showed that Xcc had evolved a complicated light-signalling system to adapt to a complex environment.

  11. Structural and functional analyses of PAS domain interactions of the clock proteins Drosophila PERIOD and mouse PERIOD2.

    PubMed

    Hennig, Sven; Strauss, Holger M; Vanselow, Katja; Yildiz, Ozkan; Schulze, Sabrina; Arens, Julia; Kramer, Achim; Wolf, Eva

    2009-04-28

    PERIOD proteins are central components of the Drosophila and mammalian circadian clocks. The crystal structure of a Drosophila PERIOD (dPER) fragment comprising two PER-ARNT-SIM (PAS) domains (PAS-A and PAS-B) and two additional C-terminal alpha-helices (alphaE and alphaF) has revealed a homodimer mediated by intermolecular interactions of PAS-A with tryptophane 482 in PAS-B and helix alphaF. Here we present the crystal structure of a monomeric PAS domain fragment of dPER lacking the alphaF helix. Moreover, we have solved the crystal structure of a PAS domain fragment of the mouse PERIOD homologue mPER2. The mPER2 structure shows a different dimer interface than dPER, which is stabilized by interactions of the PAS-B beta-sheet surface including tryptophane 419 (equivalent to Trp482dPER). We have validated and quantitatively analysed the homodimer interactions of dPER and mPER2 by site-directed mutagenesis using analytical gel filtration, analytical ultracentrifugation, and co-immunoprecipitation experiments. Furthermore we show, by yeast-two-hybrid experiments, that the PAS-B beta-sheet surface of dPER mediates interactions with TIMELESS (dTIM). Our study reveals quantitative and qualitative differences between the homodimeric PAS domain interactions of dPER and its mammalian homologue mPER2. In addition, we identify the PAS-B beta-sheet surface as a versatile interaction site mediating mPER2 homodimerization in the mammalian system and dPER-dTIM heterodimer formation in the Drosophila system.

  12. Offshore Deepwater Liquified Natural Gas (LNG) Ports ...

    EPA Pesticide Factsheets

    2017-04-10

    EPA received three National Pollution Discharge Elimination System (NPDES) permit applications for wastewater discharges related to the construction and operation of deepwater LNG ports in state and federal waters of Massachusetts Bay. One was for construction-related discharges associated with the Northeast Gateway LNG deepwater port, one was for operations-related discharges associated with the Northeast Gateway LNG deepwater port, and the other was for both construction-related and operations-related discharges for the Neptune LNG deepwater port.

  13. Integrated image monitoring system using head-mounted display for gasless single-port clampless partial nephrectomy.

    PubMed

    Kihara, Kazunori; Saito, Kazutaka; Komai, Yoshinobu; Fujii, Yasuhisa

    2014-12-01

    A novel head-mounted display (HMD) offers a higher quality of endoscopic imagery in front of the eyes regardless of head position. We present an application of the HMD system as a personal integrated multi-image monitoring system in gasless single-port clampless partial nephrectomy (PN). Our HMD system displayed multiple forms of information as integrated, sharp, high-contrast images both seamlessly and synchronously using a four-split screen. The surgeon wearing an HMD display could continuously and simultaneously monitor the endoscopic, three-dimensional (3D) video and intraoperative ultrasound images. In addition, the operator can rotate the 3D video image using fingertip movements on the finger tracking system. All two clampless partial nephrectomies were safely completed within the operative time, blood loss was within usual limits and there were no complications. The integrated image HMD system might facilitate maneuverability and safety in minimally invasive clampless PN.

  14. Factors of Stream Instability in Urban Centres of Southern Nigeria: Case Study of Port Harcourt City River Systems.

    NASA Astrophysics Data System (ADS)

    Amangabara, G. T.

    2006-05-01

    There are two main drainage rivers in the Port Harcourt Metropolis - The Ntamogba and the Woji creek (Abam, 2004). There are a few other drainage rivers that are equally important e.g. the Nwaja River that drains Rumukalagbor, Elekahia, New GRA Phases IV and V, Presidential Housing Estate and Sun Ray publications Area of Aba Road. These river systems drain the entire Port Harcourt City dividing the City into three major drainage zones. Since the discovery of oil in Nigeria in the 1950s, the country has been suffering the negative environmental consequences of oil development. The growth of the country's oil industry, combined with population explosion and a lack of environmental regulations, led to substantial damage to Nigeria's environment, especially in the Niger Delta region, the center of the country's oil industry. Uncontrolled population movement as well as spontaneous housing development on marginal lands such as stream corridors, has led to the degradation of all major stream channels in the Nation's oil capital - Port Harcourt City. The longitudinal profiles and cross sections of reaches of three major streams (Ntamogba, Nwaja, and Oginigba streams) were investigated. Land use maps of 1979 1999 and 2004 were used. Our result showed that 1). Almost all of the stream corridors have been built up without adequate plan 2). The natural grades have been distorted by channelisation for the purpose of flood evacuation without geomorphic consideration .3). Our research also shows that the interface of saline water and fresh water has extended upstream affecting urban infrastructure. 4) localized damming and sedimentation behind hydraulic structures were common occurrences) our overall result indicate that two episodes of channel incision on Oginigba stream had increased slope reduced sinuosity increased entrenchment and reduce width-depth ratio . Conclusively the factors of the instability of theses urban streams are manly the processes of urbanization which

  15. Economic and environmental impacts on ports and harbors from the convention to ban harmful marine anti-fouling systems.

    PubMed

    Champ, Michael A

    2003-08-01

    The recent Diplomatic Conference held (1-5 October 2001) by the International Maritime Organization (IMO) in London adopted the Draft Convention prepared by The Marine Environmental Protection Committee (MEPC) of IMO for the "Control of Harmful Anti-fouling Systems for Ships." The convention has been developed to immediately ban the use of Tributyltin (TBT) globally in anti-fouling paints to "protect the marine environment". The ban on TBT has come about because TBT has detrimental effects on non-target marine organisms. In November 1999, IMO agreed that a treaty be developed by the MEPC to ensure a ban on the application of TBT based anti-fouling paints by 1 January 2003, and a ban on the use of TBT by 1 January 2008. At the meeting surious concern was expressed by some experts for the need to identify in the treaty the necessary regulatory language for: (1) the "safe" removal, treatment, and disposal of marine anti-foulants deemed "harmful" by the treaty and (2) who is liable for the future dredging and disposal of TBT-contaminated port and harbor sediments--to also "protect the marine environment". The requirement for "safe" removal and disposal was incorporated at MEPC 46 as Article 5 in the treaty, without it shipyards complying with existing national and local discharge regulations (most have none for discharge of TBT) could inadvertently release more TBT to ports and harbors in the five-year compliance period than has been leached from ships (hulls) in the past 40 years to the same waters. Virginia is the only State in the US that regulates the discharge to below 50 ng/l (50 parts per trillion). However, the liability for the future dredging and disposal costs of TBT-contaminated port and harbor sediments has not been addressed.

  16. The evolution of PAs in the Canadian Armed Forces.

    PubMed

    Mertens, Jonathan; Descoteaux, Marc

    2017-01-01

    This study documents the growing role of the physician assistant (PA) in the Canadian Armed Forces. PAs have served as the backbone of the Royal Canadian Medical Services' frontline medical operations since 1984, on land, aboard ships and submarines, and domestically in garrison. Candidates begin as medical technicians and receive advanced training to become PAs at midcareer. The current rank of PAs as warrant officers is evolving and a commissioned status is under consideration.

  17. PAS kinase: a nutrient sensing regulator of glucose homeostasis.

    PubMed

    DeMille, Desiree; Grose, Julianne H

    2013-11-01

    Per-Arnt-Sim (PAS) kinase (PASK, PASKIN, and PSK) is a member of the group of nutrient sensing protein kinases. These protein kinases sense the energy or nutrient status of the cell and regulate cellular metabolism appropriately. PAS kinase responds to glucose availability and regulates glucose homeostasis in yeast, mice, and man. Despite this pivotal role, the molecular mechanisms of PAS kinase regulation and function are largely unknown. This review focuses on what is known about PAS kinase, including its conservation from yeast to man, identified substrates, associated phenotypes and role in metabolic disease.

  18. Near-Port Communities

    EPA Pesticide Factsheets

    Information to help near-port community leaders participate effectively in the decision-making process by increasing the understanding of the role of ports, how ports can impact local land use, economic trends, and environment.

  19. [The Public Health Services Port-folio in the National Health System: the contribution of the Central Government of Spain].

    PubMed

    Villalbí, Joan R; Carreras, Fernando; Martín-Moreno, José M; Hernández-Aguado, Ildefonso

    2010-01-01

    This paper concentrates on the port folio of public health services in the National Health System, with an inventory of those provided by the central level of government in the currently decentralized context of Spain. There is an important activity in public health, with some dispersion among different bodies and organisations. Most of the current activities of the central level of government concentrate in monitoring health levels and their determinants, managing information systems and health alerts and warnings, but with an involvement in policy development, both as a counterpart of the European Union and as an active agent with both regional levels of government and other organisations influencing public health. Besides, this level of government assures some essential services with little visibility for the general population as they are mostly delivered to other public administrations or to professional groups.

  20. Reproducing system-level bulk current injection test in direct power injection setup for multiple-port DUTs

    NASA Astrophysics Data System (ADS)

    Miropolsky, S.; Frei, S.

    2013-07-01

    Many investigations have been published on the transferability of RF immunity test results between system and IC-levels. The RF signal level at DUT (Device under Test) inputs, i.e. either RF voltage amplitude or RF input current, is used as a reference value for the load on the DUT. Existing approaches analyze the DUT response as a function of the RF signal level at a single input pin, e.g. supply voltage. Sufficient accuracy of such an approach could be shown in several cases, but results are not sufficient as a general solution for complex DUT. This paper proposes both theoretical analysis and practical implementation of a DPI setup, where a disturbance, equivalent to system-level BCI setup, can be delivered to multiple DUT input ports.

  1. Survival of Aerobic and Anaerobic Bacteria in Purulent Clinical Specimens Maintained in the Copan Venturi Transystem and Becton Dickinson Port-a-Cul Transport Systems

    PubMed Central

    Citron, Diane M.; Warren, Yumi A.; Hudspeth, Marie K.; Goldstein, Ellie J. C.

    2000-01-01

    Recovery of aerobic and anaerobic bacteria from clinical specimens maintained in the Copan Venturi Transystem and the Becton Dickinson Port-a-Cul transport was assessed. Of 54 anaerobes, 53 were recovered after 4 h, and 52 were recovered after 24 h, from both systems. After 48 h, 45 and 50 were recovered from the two systems, respectively. PMID:10655410

  2. 3-Port Single-Stage PV & Battery Converter Improves Efficiency and Cost in Combined PV/Battery Systems

    SciTech Connect

    Bundschuh, Paul

    2013-03-23

    Due to impressive cost reductions in recent years, photovoltaic (PV) generation is now able to produce electricity at highly competitive prices, but PV’s inherent intermittency reduces the potential value of this energy. The integration of battery storage with PV will be transformational by increasing the value of solar. Utility scale systems will benefit by firming intermittency including PV ramp smoothing, grid support and load shifting, allowing PV to compete directly with conventional generation. For distributed grid-tied PV adding storage will reduce peak demand utility charges, as well as providing backup power during power grid failures. The largest long term impact of combined PV and battery systems may be for delivering reliable off-grid power to the billions of individuals globally without access to conventional power grids, or for billions more that suffer from daily power outages. PV module costs no longer dominate installed PV system costs. Balance-of-System (BOS) costs including the PV inverter and installation now contribute the majority of installed system costs. Battery costs are also dropping faster than installation and battery power converter systems. In each of these separate systems power converters have become a bottleneck for efficiency, cost and reliability. These bottlenecks are compounded in hybrid power conversion systems that combine separate PV and battery converters. Hybrid power conversion systems have required multiple power converters hardware units and multiple power conversion steps adding to efficiency losses, product and installation costs, and reliability issues. Ideal Power Converters has developed and patented a completely new theory of operation for electronic power converters using its indirect EnergyPacket Switching™ topology. It has established successful power converter products for both PV and battery systems, and its 3-Port Hybrid Converter is the first product to exploit the topology’s capability for the

  3. Comparison of the Accu-CulShure system and a swab placed in a B-D Port-a-Cul tube for specimen collection and transport.

    PubMed

    Baron, E J; Väisänen, M L; McTeague, M; Strong, C A; Norman, D; Finegold, S M

    1993-06-01

    We compared the Accu-CulShure guarded specimen collection device and a swab inserted into a B-D Port-a-Cul transport tube in terms of their efficacy under ideal conditions for recovery of bacteria from 10 decubitus ulcer specimens. Cultures yielded 57 aerobes and 21 anaerobes; 76 isolates were recovered with use of Accu-CulShure, and 72 isolates were recovered with use of Port-a-Cul. Both systems were comparable for recovery of organisms in terms of quantitative and qualitative results.

  4. Port and Harbor Security

    SciTech Connect

    Saito, T; Guthmuller, H; DeWeert, M

    2004-12-15

    Port and Harbor Security is a daunting task to which optics and photonics offers significant solutions. We are pleased to report that the 2005 Defense and Security Symposium (DSS, Orlando, FL) will include reports on active and passive photonic systems operating from both airborne and subsurface platforms. In addition to imaging techniques, there are various photonic applications, such as total internal reflection fluorescence (TIRF), which can be used to ''sniff'' for traces of explosives or contaminants in marine. These non-imaging technologies are beyond the scope of this article, but will also be represented at DSS 2005. We encourage colleagues to join our technical group to help us to make our ports and harbors safer and more secure.

  5. New three-dimensional head-mounted display system, TMDU-S-3D system, for minimally invasive surgery application: procedures for gasless single-port radical nephrectomy.

    PubMed

    Kihara, Kazunori; Fujii, Yasuhisa; Masuda, Hitoshi; Saito, Kazutaka; Koga, Fumitaka; Matsuoka, Yoh; Numao, Noboru; Kojima, Kazuyuki

    2012-09-01

    We present an application of a new three-dimensional head-mounted display system that combines a high-definition three-dimensional organic electroluminescent head-mounted display with a high-definition three-dimensional endoscope to minimally invasive surgery, using gasless single-port radical nephrectomy procedures as a model. This system presents the surgeon with a higher quality of magnified three-dimensional imagery in front of the eyes regardless of head position, and simultaneously allows direct vision by moving the angle of sight downward. It is also significantly less expensive than the current robotic surgery system. While carrying out gasless single-port radical nephrectomy, the system provided the surgeon with excellent three-dimensional imagery of the operative field, direct vision of the outside and inside of the patient, and depth perception and tactile feedback through the devices. All four nephrectomies were safely completed within the operative time, blood loss was within usual limits and there were no complications. The display was light enough to comfortably be worn for a long operative time. Our experiences show that the three-dimensional head-mounted display system might facilitate maneuverability and safety in minimally invasive procedures, without prohibitive cost, and thus might mitigate the drawbacks of other three-dimensional vision systems. Because of the potential benefits that this system offers, it deserves further refinements of its role in various minimally invasive surgeries.

  6. British community pharmacists' views of physician-assisted suicide (PAS)

    PubMed Central

    Hanlon, T.; Weiss, M.; Rees, J.

    2000-01-01

    Objectives— To explore British community pharmacists' views on PAS , including professional responsibility, personal beliefs, changes in law and ethical guidance. Design— Postal questionnaire Setting— Great Britain Subjects— A random sample of 320 registered full-time community pharmacists Results— The survey yielded a response rate of 56%. The results showed that 70% of pharmacists agreed that it was a patient's right to choose to die, with 57% and 45% agreeing that it was the patient's right to involve his/her doctor in the process and to use prescription medicines, respectively. Forty-nine per cent said that they would knowingly dispense a prescription for use in PAS were it to be legalised and 54% believed it correct to refuse to dispense such a prescription. Although 53% believed it to be their right to know when they were being involved in PAS, 28% did not. Most pharmacists (90%) said that they would wish to see the inclusion of a practice protocol for PAS in the code of ethics of the Royal Pharmaceutical Society of Great Britain (CE-RPSGB) in the event of a change in the law on PAS. In addition, 89% would wish to see PAS included in the Conscience Clause of the CE-RPSGB. Males were found to be significantly less likely to favour PAS than females (p<0.05), as were those declaring an ethnic/religious background of consideration when dealing with ethical issues in practice compared with their counterparts (p<0.00005). Conclusion— Pharmacists view their professional responsibility in PAS to be more obligatory than a physician's, in having to provide the means for PAS. It is worrying that a proportion of the respondents prefer to remain in ignorance of the true purpose of a prescription for PAS; a finding at odds with current developments within the pharmaceutical profession. A practice protocol for PAS and an extension of the conscience clause should be considered in the event of PAS becoming legal. Such measures would allow the efficient provision

  7. Virtual wall-based haptic-guided teleoperated surgical robotic system for single-port brain tumor removal surgery.

    PubMed

    Seung, Sungmin; Choi, Hongseok; Jang, Jongseong; Kim, Young Soo; Park, Jong-Oh; Park, Sukho; Ko, Seong Young

    2017-01-01

    This article presents a haptic-guided teleoperation for a tumor removal surgical robotic system, so-called a SIROMAN system. The system was developed in our previous work to make it possible to access tumor tissue, even those that seat deeply inside the brain, and to remove the tissue with full maneuverability. For a safe and accurate operation to remove only tumor tissue completely while minimizing damage to the normal tissue, a virtual wall-based haptic guidance together with a medical image-guided control is proposed and developed. The virtual wall is extracted from preoperative medical images, and the robot is controlled to restrict its motion within the virtual wall using haptic feedback. Coordinate transformation between sub-systems, a collision detection algorithm, and a haptic-guided teleoperation using a virtual wall are described in the context of using SIROMAN. A series of experiments using a simplified virtual wall are performed to evaluate the performance of virtual wall-based haptic-guided teleoperation. With haptic guidance, the accuracy of the robotic manipulator's trajectory is improved by 57% compared to one without. The tissue removal performance is also improved by 21% ( p < 0.05). The experiments show that virtual wall-based haptic guidance provides safer and more accurate tissue removal for single-port brain surgery.

  8. Histopathological examination of nail clippings using PAS staining (HPE-PAS): gold standard in diagnosis of Onychomycosis.

    PubMed

    Jeelani, Shazia; Ahmed, Qazi Masood; Lanker, Audil Mohmad; Hassan, Iffat; Jeelani, Nasir; Fazili, Tawheeda

    2015-01-01

    Onychomycosis is fungal infection of one or more of the nail units. However, because fungi cause only about half of all nail dystrophies, the use of appropriate diagnostic techniques is important to ensure correct diagnosis and treatment. Aim of the present study was to compare direct microscopy, culture and HPE-PAS for diagnosis of onychomycosis by evaluating their sensitivity and various other relevant statistical parameters. A prospective, hospital-based, cross-sectional study was conducted on 216 patients with a high degree of clinical suspicion of onychomycosis. Nail specimens were evaluated using three diagnostic methods, i.e. direct microscopy using 20% Potassium hydroxide (KOH) & 40% Di-methyl-suphoxide (DMSO), culture and histopathological examination using PAS stain (HPE-PAS). Of 216 patients direct microscopy was positive in 138 (63.9%), culture in 147 (68%) and HPE-PAS in 164 patients (76%). One hundred and seventy-nine patients fitted into the criteria set for confirmed diagnosis of onychomycosis. Using this as a denominator; direct microscopy, culture and HPE-PAS had sensitivities of 77.1%, 70% and 91.6% respectively. Also, HPE-PAS showed the highest sensitivity of 94.7% in 19 cases with prediagnostic antimycotic treatment compared to direct microscopy (42.1%) or culture (57.9%). HPE-PAS shows high sensitivity for diagnosis of onychomycosis and can be considered as a gold standard in the diagnosis of onychomycosis.

  9. Feasibility of classification of clay minerals by using PAS

    NASA Astrophysics Data System (ADS)

    Honda, Y.; Yoshida, Y.; Akiyama, Y.; Nishijima, S.

    2015-06-01

    After the nuclear power plant disaster, the evaluation of radioactive Cs kept in soil, especially in clay minerals and the elucidation of its movement are urgent subjects to promote decontamination. It is known that the extractable level of Cs depends on the sort of clay minerals. We tried to find the characteristics of clay minerals belonging to phillosilicate group using positron annihilation spectroscopy (PAS) and the relationship between the results of PAS and the amounts of substantially extracted Cs from the clay minerals. The results showed that each clay mineral was found to be distinguishable from other clay minerals by PAS and the extraction rate of Cs was different among those clay minerals, however the direct correlation between the results of PAS and the extraction rates of Cs was not found.

  10. 78 FR 7334 - Port Authority Access to Facility Vulnerability Assessments and the Integration of Security Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-01

    ... ] systems operated or maintained by certain law enforcement agencies and the Coast Guard. DATES: Comments... the maximum extent practical,'' the facility's security systems ``with compatible systems operated or... systems operated or maintained by the appropriate State and local law enforcement agencies and the...

  11. ePORT, NASA's Computer Database Program for System Safety Risk Management Oversight (Electronic Project Online Risk Tool)

    NASA Technical Reports Server (NTRS)

    Johnson, Paul W.

    2008-01-01

    ePORT (electronic Project Online Risk Tool) provides a systematic approach to using an electronic database program to manage a program/project risk management processes. This presentation will briefly cover the standard risk management procedures, then thoroughly cover NASA's Risk Management tool called ePORT. This electronic Project Online Risk Tool (ePORT) is a web-based risk management program that provides a common framework to capture and manage risks, independent of a programs/projects size and budget. It is used to thoroughly cover the risk management paradigm providing standardized evaluation criterion for common management reporting, ePORT improves Product Line, Center and Corporate Management insight, simplifies program/project manager reporting, and maintains an archive of data for historical reference.

  12. Exploratory studies of extended storage of apheresis platelets in a platelet additive solution (PAS).

    PubMed

    Slichter, Sherrill J; Corson, Jill; Jones, Mary Kay; Christoffel, Todd; Pellham, Esther; Bailey, S Lawrence; Bolgiano, Doug

    2014-01-09

    To evaluate the poststorage viability of apheresis platelets stored for up to 18 days in 80% platelet additive solution (PAS)/20% plasma, 117 healthy subjects donated platelets using the Haemonetics MCS+, COBE Spectra (Spectra), or Trima Accel (Trima) systems. Control platelets from the same subjects were compared with their stored test PAS platelets by radiolabeling their stored and control platelets with either (51)chromium or (111)indium. Trima platelets met Food and Drug Administration poststorage platelet viability criteria for only 7 days vs almost 13 days for Haemonetics platelets; ie, platelet recoveries after these storage times averaged 44 ± 3% vs 49 ± 3% and survivals were 5.4 ± 0.3 vs 4.6 ± 0.3 days, respectively. The differences in storage duration are likely related to both the collection system and the storage bag. The Spectra and Trima platelets were hyperconcentrated during collection, and PAS was added, whereas the Haemonetics platelets were elutriated with PAS, which may have resulted in less collection injury. When Spectra and Trima platelets were stored in Haemonetics' bags, poststorage viability was significantly improved. Platelet viability is better maintained in vitro than in vivo, allowing substantial increases in platelet storage times. However, implementation will require resolution of potential bacterial overgrowth during storage.

  13. Port-Wine Stains

    MedlinePlus

    ... their own, they can be treated. In fact, laser therapies can make many port-wine stains much ... mark might be. The good news is that lasers (highly concentrated light energy) can make many port- ...

  14. Multi-port valve

    DOEpatents

    Lewin, Keith F.

    1997-04-15

    A multi-port valve for regulating, as a function of ambient air having varying wind velocity and wind direction in an open-field control area, the distribution of a fluid, particularly carbon dioxide (CO.sub.2) gas, in a fluid distribution system so that the control area remains generally at an elevated fluid concentration or level of said fluid. The multi-port valve generally includes a multi-port housing having a plurality of outlets therethrough disposed in a first pattern of outlets and at least one second pattern of outlets, and a movable plate having a plurality of apertures extending therethrough disposed in a first pattern of apertures and at least one second pattern of apertures. The first pattern of apertures being alignable with the first pattern of outlets and the at least one second pattern of apertures being alignable with the second pattern of outlets. The first pattern of apertures has a predetermined orientation with the at least one second pattern of apertures. For an open-field control area subject to ambient wind having a low velocity from any direction, the movable plate is positioned to equally distribute the supply of fluid in a fluid distribution system to the open-field control area. For an open-field control area subject to ambient wind having a high velocity from a given direction, the movable plate is positioned to generally distribute a supply of fluid in a fluid distribution system to that portion of the open-field control area located upwind.

  15. Multi-port valve

    DOEpatents

    Lewin, K.F.

    1997-04-15

    A multi-port valve is described for regulating, as a function of ambient air having varying wind velocity and wind direction in an open-field control area, the distribution of a fluid, particularly carbon dioxide (CO{sub 2}) gas, in a fluid distribution system so that the control area remains generally at an elevated fluid concentration or level of said fluid. The multi-port valve generally includes a multi-port housing having a plurality of outlets there through disposed in a first pattern of outlets and at least one second pattern of outlets, and a movable plate having a plurality of apertures extending there through disposed in a first pattern of apertures and at least one second pattern of apertures. The first pattern of apertures being alignable with the first pattern of outlets and the at least one second pattern of apertures being alignable with the second pattern of outlets. The first pattern of apertures has a predetermined orientation with the at least one second pattern of apertures. For an open-field control area subject to ambient wind having a low velocity from any direction, the movable plate is positioned to equally distribute the supply of fluid in a fluid distribution system to the open-field control area. For an open-field control area subject to ambient wind having a high velocity from a given direction, the movable plate is positioned to generally distribute a supply of fluid in a fluid distribution system to that portion of the open-field control area located upwind. 7 figs.

  16. Characterization of the PAS domain in the sensor-kinase BvgS: mechanical role in signal transmission

    PubMed Central

    2013-01-01

    Background In bacteria, signal-transduction two-component systems are major players for adaptation to environmental stimuli. The perception of a chemical or physical signal by a sensor-kinase triggers its autophosphorylation. The phosphoryl group is then transferred to the cognate response regulator, which mediates the appropriate adaptive response. Virulence of the whooping cough agent Bordetella pertussis is controlled by the two-component system BvgAS. Atypically, the sensor-kinase BvgS is active without specific stimuli at 37°C in laboratory conditions and is inactivated by the addition of negative chemical modulators. The structure of BvgS is complex, with two tandem periplasmic Venus flytrap domains and a cytoplasmic PAS domain that precedes the kinase domain, which is followed by additional phosphotransfer domains. PAS domains are small, ubiquitous sensing or regulatory domains. The function of the PAS domain in BvgS remains unknown. Results We showed that recombinant BvgS PAS proteins form dimers that are stabilized by α helical regions flanking the PAS core. A structural model of the PAS domain dimer was built and probed by site-directed mutagenesis and by biochemical and functional analyses. Although we found no ligands for the PAS domain cavity, its integrity is required for signaling. We also showed that the structural stability of the PAS core and its proper coupling to its flanking N- and C-terminal α helices are crucial for BvgS activity. Conclusions We propose that a major function of the BvgS PAS domain is to maintain conformational signals arising from mechanical strain generated by the periplasmic domain. The tight structure of the PAS core and its connections with the upstream and downstream helices ensure signaling to the kinase domain, which determines BvgS activity. Many mild substitutions that map to the PAS domain keep BvgS active but make it unresponsive to negative modulators, supporting that modulation increases conformational strain

  17. Porting GENESIS to SIMULINK.

    PubMed

    Rodriguez Campos, Francisco; Enderle, John D

    2004-01-01

    This paper describes the porting of the general simulation system (GENESIS) to Matrix Language Laboratory language (MatLab) SIMULINK, based in the cable theory to simulate the behavior of neurons. A graphic programming approach serves as ideal platform for teaching physiological modeling and neuroengineering courses. The ultimate goal of this project is to integrate all of the chemical, electrical, material, mechanical and neural interactions into a single model that can be viewed seamlessly from a molecular model to the large scale model. Integration of all interactions is not possible with GENESIS, but can be accomplished with SIMULINK.

  18. GlobePort Faces Global Business Challenges--Assessing the Organizational Side of Information Systems Projects

    ERIC Educational Resources Information Center

    Ghosh, Biswadip

    2011-01-01

    Published studies have reported that Information System (IS) projects succeed or fail based on how effectively the organizational issues were understood and addressed in the specification, development and implementation stages of the project. This is particularly true in the design and delivery of Inter-Organizational Systems (IOS) that can affect…

  19. Structural properties of PAS domains from the KCNH potassium channels.

    PubMed

    Adaixo, Ricardo; Harley, Carol A; Castro-Rodrigues, Artur F; Morais-Cabral, João H

    2013-01-01

    KCNH channels form an important family of voltage gated potassium channels. These channels include a N-terminal Per-Arnt-Sim (PAS) domain with unknown function. In other proteins PAS domains are implicated in cellular responses to environmental queues through small molecule binding or involvement in signaling cascades. To better understand their role we characterized the structural properties of several channel PAS domains. We determined high resolution structures of PAS domains from the mouse EAG (mEAG), drosophila ELK (dELK) and human ERG (hERG) channels and also of the hERG domain without the first nine amino acids. We analyzed these structures for features connected to ligand binding and signaling in other PAS domains. In particular, we have found cavities in the hERG and mEAG structures that share similarities with the ligand binding sites from other PAS domains. These cavities are lined by polar and apolar chemical groups and display potential flexibility in their volume. We have also found that the hydrophobic patch on the domain β-sheet is a conserved feature and appears to drive the formation of protein-protein contacts. In addition, the structures of the dELK domain and of the truncated hERG domain revealed the presence of N-terminal helices. These helices are equivalent to the helix described in the hERG NMR structures and are known to be important for channel function. Overall, these channel domains retain many of the PAS domain characteristics known to be important for cell signaling.

  20. J-PAS: The Javalambre Physics of the Accelerated Universe Astrophysical Survey

    NASA Astrophysics Data System (ADS)

    Cepa, J.; Benítez, N.; Dupke, R.; Moles, M.; Sodré, L.; Cenarro, A. J.; Marín-Franch, A.; Taylor, K.; Cristóbal, D.; Fernández-Soto, A.; Mendes de Oliveira, C.; Abramo, L. R.; Alcaniz, J. S.; Overzier, R.; Hernández-Monteagudo, A.; Alfaro, E. J.; Kanaan, A.; Carvano, M.; Reis, R. R. R.; J-PAS Team

    2016-10-01

    The Javalambre Physics of the Accelerated Universe Astrophysical Survey (J-PAS) is a narrow band, very wide field Cosmological Survey to be carried out from the Javalambre Observatory in Spain with a purpose-built, dedicated 2.5 m telescope and a 4.7 sq.deg. camera with 1.2 Gpix. Starting in late 2016, J-PAS will observe 8500 sq.deg. of Northern Sky and measure Δz˜0.003(1+z) photo-z for 9× 107 LRG and ELG galaxies plus several million QSOs, sampling an effective volume of ˜ 14 Gpc3 up to z=1.3 and becoming the first radial BAO experiment to reach Stage IV. J-PAS will detect 7× 105 galaxy clusters and groups, setting constraints on Dark Energy which rival those obtained from its BAO measurements. Thanks to the superb characteristics of the site (seeing ˜ 0.7 arcsec), J-PAS is expected to obtain a deep, sub-arcsec image of the Northern sky, which combined with its unique photo-z precision will produce one of the most powerful cosmological lensing surveys before the arrival of Euclid. J-PAS's unprecedented spectral time domain information will enable a self-contained SN survey that, without the need for external spectroscopic follow-up, will detect, classify and measure σz˜ 0.5 redshifts for ˜ 4000 SNeIa and ˜ 900 core-collapse SNe. The key to the J-PAS potential is its innovative approach: a contiguous system of 54 filters with 145 Å width, placed 100 Å apart over a multi-degree FoV is a powerful redshift machine, with the survey speed of a 4000 multiplexing low resolution spectrograph, but many times cheaper and much faster to build. The J-PAS camera is equivalent to a 4.7 sq.deg. IFU and it will produce a time-resolved, 3D image of the Northern Sky with a very wide range of Astrophysical applications in Galaxy Evolution, the nearby Universe and the study of resolved stellar populations.

  1. GCD TechPort Data Sheets Thermal Protection System Materials (TPSM) Project

    NASA Technical Reports Server (NTRS)

    Chinnapongse, Ronald L.

    2014-01-01

    The Thermal Protection System Materials (TPSM) Project consists of three distinct project elements: the 3-Dimensional Multifunctional Ablative Thermal Protection System (3D MAT) project element; the Conformal Ablative Thermal Protection System (CA-TPS) project element; and the Heatshield for Extreme Entry Environment Technology (HEEET) project element. 3D MAT seeks to design, develop and deliver a game changing material solution based on 3-dimensional weaving and resin infusion approach for manufacturing a material that can function as a robust structure as well as a thermal protection system. CA-TPS seeks to develop and deliver a conformal ablative material designed to be efficient and capable of withstanding peak heat flux up to 500 W/ sq cm, peak pressure up to 0.4 atm, and shear up to 500 Pa. HEEET is developing a new ablative TPS that takes advantage of state-of-the-art 3D weaving technologies and traditional manufacturing processes to infuse woven preforms with a resin, machine them to shape, and assemble them as a tiled solution on the entry vehicle substructure or heatshield.

  2. System and method for filling a plurality of isolated vehicle fluid circuits through a common fluid fill port

    DOEpatents

    Sullivan, Scott C; Fansler, Douglas

    2014-10-14

    A vehicle having multiple isolated fluid circuits configured to be filled through a common fill port includes a first fluid circuit disposed within the vehicle, the first fluid circuit having a first fill port, a second fluid circuit disposed within the vehicle, and a conduit defining a fluid passageway between the first fluid circuit and second fluid circuit, the conduit including a valve. The valve is configured such that the first and second fluid circuits are fluidly coupled via the passageway when the valve is open, and are fluidly isolated when the valve is closed.

  3. Ceci n'est pas une micromachine.

    SciTech Connect

    Yarberry, Victor R.; Diegert, Carl F.

    2010-03-01

    The image created in reflected light DIC can often be interpreted as a true three-dimensional representation of the surface geometry, provided a clear distinction can be realized between raised and lowered regions in the specimen. It may be helpful if our definition of saliency embraces work on the human visual system (HVS) as well as the more abstract work on saliency, as it is certain that understanding by humans will always stand between recording of a useful signal from all manner of sensors and so-called actionable intelligence. A DARPA/DSO program lays down this requirement in a current program (Kruse 2010): The vision for the Neurotechnology for Intelligence Analysts (NIA) Program is to revolutionize the way that analysts handle intelligence imagery, increasing both the throughput of imagery to the analyst and overall accuracy of the assessments. Current computer-based target detection capabilities cannot process vast volumes of imagery with the speed, flexibility, and precision of the human visual system.

  4. Extracytoplasmic PAS-like domains are common in signal transduction proteins.

    SciTech Connect

    Schiffer, M.; Chang, C.; Tesar, C.; Gu, M.; Babnigg, G.; Joachimiak, A.; Pokkuluri, P. R.; Szurmant, H.; Biosciences Division; Scripps Research Inst.

    2010-02-01

    We present the crystal structure of the extracytoplasmic domain of the Bacillus subtilis PhoR sensor histidine kinase, part of a two-component system involved in adaptation to low environmental phosphate concentrations. In addition to the PhoR structure, we predict that the majority of the extracytoplasmic domains of B. subtilis sensor kinases will adopt a fold similar to the ubiquitous PAS domain.

  5. Extracytoplasmic pas-like domains are common in signal transduction proteins. ;

    SciTech Connect

    Chang, C.; Tesar, C.; Gu, M.; Babnigg, G.; Joachimiak, A.; Pokkuluri, P. R.; Szurmant, H.; Schiffer, M.

    2010-02-01

    We present the crystal structure of the extracytoplasmic domain of the Bacillus subtilis PhoR sensor histidine kinase, part of a two-component system involved in adaptation to low environmental phosphate concentrations. In addition to the PhoR structure, we predict that the majority of the extracytoplasmic domains of B. subtilis sensor kinases will adopt a fold similar to the ubiquitous PAS domain.

  6. Specific learning curve for port placement and docking of da Vinci(®) Surgical System: one surgeon's experience in robotic-assisted radical prostatectomy.

    PubMed

    Dal Moro, F; Secco, S; Valotto, C; Artibani, W; Zattoni, F

    2012-12-01

    Port placement and docking of the da Vinci(®) Surgical System is fundamental in robotic-assisted laparoscopic radical prostatectomy (RALP). The aim of our study was to investigate learning curves for port placement and docking of robots (PPDR) in RALP. This manuscript is a retrospective review of prospectively collected data looking at PPDR in 526 patients who underwent RALP in our institute from April 2005 to May 2010. Data included patient-factor features such as body mass index (BMI), and pre-, intra- and post-operative data. Intra-operative information included operation time, subdivided into anesthesia, PPDR and console times. 526 patients underwent RALP, but only those in whom PPDR was performed by the same surgeon without laparoscopic and robotic experience (F.D.M.) were studied, totalling 257 cases. The PPDR phase revealed an evident learning curve, comparable with other robotic phases. Efficiency improved until approximately the 60th case (P < 0.001), due more to effective port placement than to docking of robotic arms. In our experience, conversion to open surgery is so rare that statistical evaluation is not significant. Conversion due to robotic device failure is also very rare. This study on da Vinci procedures in RALP revealed a learning curve during PPDR and throughout the robotic-assisted procedure, reaching a plateau after 60 cases.

  7. Tsunami currents in ports.

    PubMed

    Borrero, Jose C; Lynett, Patrick J; Kalligeris, Nikos

    2015-10-28

    Tsunami-induced currents present an obvious hazard to maritime activities and ports in particular. The historical record is replete with accounts from ship captains and harbour masters describing their fateful encounters with currents and surges caused by these destructive waves. Despite the well-known hazard, only since the trans-oceanic tsunamis of the early twenty-first century (2004, 2010 and 2011) have coastal and port engineering practitioners begun to develop port-specific warning and response products that accurately assess the effects of tsunami-induced currents in addition to overland flooding and inundation. The hazard from strong currents induced by far-field tsunami remains an underappreciated risk in the port and maritime community. In this paper, we will discuss the history of tsunami current observations in ports, look into the current state of the art in port tsunami hazard assessment and discuss future research trends.

  8. Navigation Safety Analysis in Taiwanese Ports

    NASA Astrophysics Data System (ADS)

    Liu, Chung-Ping; Liang, Gin-Shuh; Su, Yuhling; Chu, Ching-Wu

    2006-05-01

    Many researchers have studied vessel systems to enhance navigation safety at sea, or analysed the statistics of marine casualties of different flagged vessels as well as the fatalities and injuries in ferry accidents. However, little research has been devoted to port safety and especially navigation safety within Taiwanese territorial waters where over a 10-year period there have been 3428 marine accidents with 548 deaths and 524 vessels sunk. In this paper, we use the Grey Relational Analysis (GRA) to analyse the marine accident records of each of Taiwan's commercial ports from 1992 2003. Then, after interviewing the port authority managers and marine specialists, we discover the concerns felt by these professionals about Taiwanese commercial ports. We provide suggestions to strengthen port navigation safety.

  9. Searching for planetary nebulae at the Galactic halo via J-PAS and J-PLUS

    NASA Astrophysics Data System (ADS)

    Goncalves, Denise R.; Aparício-Villegas, Teresa; Akras, Stavros; Borges Fernandes, Marcelo; J-PAS Collaboration

    2015-08-01

    The Javalambre-Physics of the Accelerating Universe Astrophysical Survey (J-PAS) is a narrow-band imaging, very wide field cosmological survey to be carried out from a dedicated 2.5m telescope and a 4.7 sq.deg camera with 1.2Gpix. It will last 5 years and will observe 8500 sq.deg of Northern sky to a 5-σ magnitude depth for point sources, equivalent to i ~23.3 over an aperture of 2 arcsec2. The J-PAS filter system consists of 54 contiguous narrow band filters of 145-Å FWHM, from 3,500 to 10,000Å. Two broad-band filters will be added at the extremes, UV and IR, plus 3 SDSS g, r, and i filters. The Javalambre Photometric Local Universe Survye (J-PLUS) will be an auxiliary survey ofJ-PAS (mainly for calibration) with a dedicated 0.80m telescope. J-PLUS comprises 12 filters, including g, r, i and z SDSS ones. Though about 2,500 planetary nebulae (PNe, confirmed spectroscopically) are known in the Galaxy, only 14 objects have been convincingly identified as halo PNe. They were classified as such from their location, kinematics and chemistry. Halo PNe are able to reveal precious information for the study of low- and intermediate-mass star evolution and the early chemical conditions of the Galaxy. The characteristic low continuum and intense line emissions of PNe make them good objects to be searched by J-PAS, and even by J-PLUS. For instance, the halo PNe BoBn 1, DdDm 1 and PS 1, located somewhere between 11 and 24 kpc from the Sun, have B magnitudes of 16, 14 and 13.4, respectively. Such values are easily encompassed by J-PAS/J-PLUS, given the typical limit magnitude of the survey. Though covering a significantly smaller sky area, data from the ALHAMBRA survey were used to test our J-PAS/J-PLUS strategy to search for PNe. Our first results will be shown in this poster.

  10. Agile Port and High Speed Ship Technologies

    DTIC Science & Technology

    2009-12-31

    Report PNW Agile Port System Demonstration Center for the Commercial Deployment of Transportation Technologies milestone agenda for accomplishing the... report summarizes the results of the remaining three projects in the FY05 program cycle, in particular the PNW Agile Port System Demonstration, a system...the accomplishment of each project and the program objectives. With the submission of this report the FY05 CCDoTT Program is complete. Bibliography

  11. A three-dimensional head-mounted display system (RoboSurgeon system) for gasless laparoendoscopic single-port partial cystectomy.

    PubMed

    Fujii, Yasuhisa; Kihara, Kazunori; Yoshida, Soichiro; Ishioka, Junichiro; Matsuoka, Yoh; Numao, Noboru; Saito, Kazutaka

    2014-12-01

    We developed a new three-dimensional (3D) head-mounted display (HMD) system (RoboSurgeon system) that combines a high-definition 3D organic electroluminescent HMD with a high-definition 3D endoscope and applies it to minimally invasive surgery. This system presents the surgeon with a higher quality of magnified 3D imagery in front of the eyes, regardless of head position. We report 5 cases of RoboSurgeon gasless laparoendoscopic single-port partial cystectomy, which is carried out as part of our selective bladder-sparing protocol, with a technique utilizing both an intravesical and extravesical approach. While carrying out the surgery, the system provides the surgeon with both excellent 3D imagery of the operative field and clear imagery of the cystoscopy. All procedures were safely completed and there were no complications except for a case of postoperative lymphorrhea. Our experience shows that the 3D HMD system might facilitate maneuverability and safety in various minimally invasive procedures.

  12. Ports Primer: 4.0 Port-Community Relations

    EPA Pesticide Factsheets

    Ports support and benefit local, regional and national economies through their role in creating jobs and transporting goods. The relationship between ports and near-port communities can be complex, as illustrated by case studies.

  13. PAS/POLY-HAMP SIGNALING IN AER-2, A SOLUBLE HEME-BASED SENSOR

    PubMed Central

    Watts, Kylie J; Taylor, Barry L; Johnson, Mark S

    2011-01-01

    SUMMARY Poly-HAMP domains are widespread in bacterial chemoreceptors, but previous studies have focused on receptors with single HAMP domains. The Pseudomonas aeruginosa chemoreceptor, Aer-2, has an unusual domain architecture consisting of a PAS sensing domain sandwiched between three N-terminal and two C-terminal HAMP domains, followed by a conserved kinase control module. The structure of the N-terminal HAMP domains was recently solved, making Aer-2 the first protein with resolved poly-HAMP structure. The role of Aer-2 in P. aeruginosa is unclear, but here we show that Aer-2 can interact with the chemotaxis system of Escherichia coli to mediate repellent responses to oxygen, carbon monoxide and nitric oxide. Using this model system to investigate signaling and poly-HAMP function, we determined that the Aer-2 PAS domain binds penta-coordinated b-type heme and that reversible signaling requires four of the five HAMP domains. Deleting HAMP 2 and/or 3 resulted in a kinase-off phenotype, whereas deleting HAMP 4 and/or 5 resulted in a kinase-on phenotype. Overall, these data support a model in which ligand-bound Aer-2 PAS and HAMP 2 and 3 act together to relieve inhibition of the kinase control module by HAMP 4 and 5, resulting in the kinase-on state of the Aer-2 receptor. PMID:21255112

  14. Laser diode bars based on strain-compensated AlGaPAs/GaAs heterostructures

    SciTech Connect

    Marmalyuk, Aleksandr A; Ladugin, M A; Yarotskaya, I V; Panarin, V A; Mikaelyan, G T

    2012-01-31

    Traditional (in the AlGaAs/GaAs system) and phosphorus-compensated (in the AlGaAs/AlGaPAs/GaAs system) laser heterostructures emitting at a wavelength of 850 nm are grown by MOVPE and studied. Laser diode bars are fabricated and their output characteristics are studied. The method used to grow heterolayers allowed us to control (minimise) mechanical stresses in the AlGaPAs/GaAs laser heterostructure, which made it possible to keep its curvature at the level of the initial curvature of the substrate. It is shown that the use of a compensated AlGaPAs/GaAs heterostructure improves the linear distribution of emitting elements in the near field of laser diode arrays and allows the power - current characteristic to retain its slope at high pump currents owing to a uniform contact of all emitting elements with the heat sink. The radius of curvature of the grown compensated heterostructures turns out to be smaller than that of traditional heterostructures.

  15. Phage-Antibiotic Synergy (PAS): beta-lactam and quinolone antibiotics stimulate virulent phage growth.

    PubMed

    Comeau, André M; Tétart, Françoise; Trojet, Sabrina N; Prère, Marie-Françoise; Krisch, H M

    2007-08-29

    Although the multiplication of bacteriophages (phages) has a substantial impact on the biosphere, comparatively little is known about how the external environment affects phage production. Here we report that sub-lethal concentrations of certain antibiotics can substantially stimulate the host bacterial cell's production of some virulent phage. For example, a low dosage of cefotaxime, a cephalosporin, increased an uropathogenic Escherichia coli strain's production of the phage PhiMFP by more than 7-fold. We name this phenomenon Phage-Antibiotic Synergy (PAS). A related effect was observed in diverse host-phage systems, including the T4-like phages, with beta-lactam and quinolone antibiotics, as well as mitomycin C. A common characteristic of these antibiotics is that they inhibit bacterial cell division and trigger the SOS system. We therefore examined the PAS effect within the context of the bacterial SOS and filamentation responses. We found that the PAS effect appears SOS-independent and is primarily a consequence of cellular filamentation; it is mimicked by cells that constitutively filament. The fact that completely unrelated phages manifest this phenomenon suggests that it confers an important and general advantage to the phages.

  16. 78 FR 36014 - Deepwater Port License Application: Liberty Natural Gas, LLC, Port Ambrose Deepwater Port

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-14

    ... an application for the licensing of a liquefied natural gas deepwater port and that the application..., and operate a liquefied natural gas (LNG) deepwater port, known as Port Ambrose, located in the New... Maritime Administration Deepwater Port License Application: Liberty Natural Gas, LLC, Port...

  17. Port Stakeholder Summit - April 2014

    EPA Pesticide Factsheets

    EPA's National Port Stakeholders Summit, Advancing More Sustainable Ports, focused on actions to protect air quality while reducing climate risk and supporting economic growth, making ports more environmentally sustainable.

  18. Marketing and medicine. A basic guide for PAs.

    PubMed

    Blessing, J D; Davis, N L

    1988-07-01

    Marketing is a conscious plan to influence the behavior of others. Physician assistants can use marketing techniques to promote themselves and their profession as well as to help build a practice and improve patient services. Basic components of a marketing strategy include analysis, planning, implementation, and monitoring. Marketing tools easily accessible to PAs are the telephone (call to check on compliance); a photocopy machine (patient handouts and practice newsletters); and the mail (postcard to remind of follow-up visit).

  19. 48 CFR 52.247-40 - Ex Dock, Pier, or Warehouse, Port of Importation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Warehouse, Port of Importation. 52.247-40 Section 52.247-40 Federal Acquisition Regulations System FEDERAL... Provisions and Clauses 52.247-40 Ex Dock, Pier, or Warehouse, Port of Importation. As prescribed in 47.303-12..., pier, or warehouse, port of importation: Ex Dock, Pier, or Warehouse, Port of Importation (APR 1984)...

  20. Rotary sequencing valve with flexible port plate

    DOEpatents

    Wagner, Glenn Paul

    2005-05-10

    Rotary sequencing valve comprising a rotor having a rotor face rotatable about an axis perpendicular to the rotor face, wherein the rotor face has a plurality of openings, one or more of which are disposed at a selected radial distance from the axis, and wherein the rotor includes at least one passage connecting at least one pair of the plurality of openings. The valve includes a flexible port plate having a first side and a second side, wherein the first side faces the rotor and engages the rotor such that the flexible port plate can be rotated coaxially by the rotor and can move axially with respect to the rotor, wherein the flexible port plate has a plurality of ports between the first and second sides, which ports are aligned with the openings in the rotor face. The valve also includes a stator having a stator face disposed coaxially with the rotor and the flexible port plate, wherein the second side of the flexible port plate is in sealable, slidable rotary contact with the stator face, wherein the stator face has a plurality of openings, some of which are disposed at the selected radial distance from the axis, and wherein the plurality of openings extend as passages through the stator. The valve may be used in pressure or temperature swing adsorption systems.

  1. National Port Strategy Assessment

    EPA Pesticide Factsheets

    The assessment finds that air pollution at the Nation's ports can be significantly reduced by implementing currently available strategies and technologies to reduce emissions of harmful pollutants from diesel vehicles and engines.

  2. Port-Wine Stains

    MedlinePlus

    ... in healing and help prevent infection. Helping Kids Cope As with any birthmark, port-wine stains (especially ... these situations and take cues about how to cope with others' reactions. Practice responses so your child ...

  3. Port Security Strategy 2012

    DTIC Science & Technology

    2007-06-15

    Scanning every container is time consuming and delays container shipment. In addition, cargo containers en route to the United States from overseas...an appointment slip with barcode for all trucks that are scheduled to enter the port. Barcode scanning allows for a faster rate of processing...follows: • Status Quo. All containers are scanned for radioactive cargo before leaving the source port. Detection of radiation triggers further

  4. Geodynamic Research at the Department of Planetary Geodesy, SRC PAS

    NASA Astrophysics Data System (ADS)

    Brzeziński, Aleksander; Jóźwik, Mieczysław; Kaczorowski, Marek; Kalarus, Maciej; Kasza, Damian; Kosek, Wiesław; Nastula, Jolanta; Szczerbowski, Zbigniew; Wińska, Małgorzata; Wronowski, Roman; Zdunek, Ryszard; Zieliński, Janusz B.

    2016-06-01

    The Department of Planetary Geodesy of the Space Research Centre PAS has been conducting research on a broad spectrum of problems within a field of global dynamics of the Earth. In this report we describe the investigations on selected subjects concerning polar motion (modeling and geophysical interpretation of the Chandler wobble, hydrological excitation of seasonal signals, search for optimal prediction methods), tectonic activity in the region of the Książ Geodynamic Laboratory of the SRC, and finally the new joint Polish-Italian project GalAc analyzing feasibility and usefulness of equipping second-generation Galileo satellites with accelerometers.

  5. Depth-discrete sampling port

    DOEpatents

    Pemberton, Bradley E.; May, Christopher P.; Rossabi, Joseph; Riha, Brian D.; Nichols, Ralph L.

    1999-01-01

    A sampling port is provided which has threaded ends for incorporating the port into a length of subsurface pipe. The port defines an internal receptacle which is in communication with subsurface fluids through a series of fine filtering slits. The receptacle is in further communication through a bore with a fitting carrying a length of tubing there which samples are transported to the surface. Each port further defines an additional bore through which tubing, cables, or similar components of adjacent ports may pass.

  6. Depth-discrete sampling port

    DOEpatents

    Pemberton, Bradley E.; May, Christopher P.; Rossabi, Joseph; Riha, Brian D.; Nichols, Ralph L.

    1998-07-07

    A sampling port is provided which has threaded ends for incorporating the port into a length of subsurface pipe. The port defines an internal receptacle which is in communication with subsurface fluids through a series of fine filtering slits. The receptacle is in further communication through a bore with a fitting carrying a length of tubing there which samples are transported to the surface. Each port further defines an additional bore through which tubing, cables, or similar components of adjacent ports may pass.

  7. Peripherally Placed Totally Implantable Venous-access Port Systems of the Forearm: Clinical Experience in 763 Consecutive Patients

    SciTech Connect

    Goltz, Jan P. Scholl, Anne; Ritter, Christian O.; Wittenberg, Guenther; Hahn, Dietbert; Kickuth, Ralph

    2010-12-15

    The aim of this study is to evaluate the effectiveness and safety of percutaneously placed totally implantable venous-access ports (TIVAPs) of the forearm. Between January 2006 and October 2008, peripheral TIVAPs were implanted in 763 consecutive patients by ultrasound and fluoroscopic guidance. All catheters were implanted under local anesthesia and were tunneled subcutaneously. Indication, technical success, and complications were retrospectively analyzed according to Society of Interventional Radiology (SIR) criteria. Presence of antibiotic prophylaxis, periprocedurally administered drugs (e.g., sedation), and laboratory results at the time of implantation were analyzed. Maintenance during the service interval was evaluated. In total, 327,499 catheter-days were analyzed. Technical success rate was 99.3%. Reasons for initial failure of implantation were either unexpected thrombosis of the subclavian vein, expanding tumor mass of the mediastinum, or failure of peripheral venous access due to fragile vessels. Mean follow-up was 430 days. There were 115 complications observed (15.1%, 0.03 per 100 catheter-days), of which 33 (4.3%) were classified as early (within 30 days from implantation) and 82 (10.7%) as late. Catheter-related venous thrombosis was found in 65 (8.5%) of 763 (0.02 per 100 catheter-days) TIVAPs. Infections were observed in 41 (5.4%) of 763 (0.01 per 100 catheter-days) devices. Other complications observed included dislocation of the catheter tip (0.8%), occlusion (0.1%), or rupture (0.1%) of the port catheter. Dislocated catheters were corrected during a second interventional procedure. In conclusion, implantation of percutaneously placed peripheral TIVAPs shows a high technical success rate and low risk of early complications when ultrasound and fluoroscopic guidance are used. Late complications are observed three times as often as early complications.

  8. Comparison of two transport systems available in Japan (TERUMO kenkiporter II and BBL Port-A-Cul) for maintenance of aerobic and anaerobic bacteria.

    PubMed

    Fujimoto, Daichi; Takegawa, Hiroshi; Doi, Asako; Sakizono, Kenji; Kotani, Yoko; Miki, Kanji; Naito, Takuya; Niki, Marie; Miyamoto, Junko; Tamai, Koji; Nagata, Kazuma; Nakagawa, Atsushi; Tachikawa, Ryo; Otsuka, Kojiro; Katakami, Nobuyuki; Tomii, Keisuke

    2014-01-01

    The kenkiporter II (KP II) transport system is commonly used in many hospitals in Japan for transporting bacterial specimens to microbiology laboratories. Recently, the BBL Port-A-Cul (PAC) fluid vial became available. However, no reports thus far have compared the effectiveness of these two transport systems. We chose 4 aerobic and facultative anaerobic bacteria as well as 8 anaerobic organisms, and prepared three strains of each bacterium in culture media for placement into PAC and KP II containers. We compared the effectiveness of each transport system for preserving each organism at 6, 24, and 48 h after inoculation at room temperature. Thirty-six strains out of 12 bacteria were used in this study. The PAC system yielded better recovery in quantity of organisms than the KP II system at 6, 24 and 48 h. More strains were significantly recovered with the PAC system than with the KP II at 24 h (36/36 vs. 23/36, P < 0.001) and 48 h (30/36 vs. 12/36, P < 0.001). The PAC system was better in the recovery of viable organisms counted at 24 and 48 h after inoculation compared with the KP II system. The PAC system may be recommended for the transfer of bacterial specimens in clinical settings.

  9. Biological control of Aeromonas salmonicida subsp. salmonicida infection in rainbow trout (Oncorhynchus mykiss) using Aeromonas phage PAS-1.

    PubMed

    Kim, J H; Choresca, C H; Shin, S P; Han, J E; Jun, J W; Park, S C

    2015-02-01

    The potential control efficacy of Aeromonas phage PAS-1 was evaluated against Aeromonas salmonicida subsp. salmonicida infection in rainbow trout (Oncorhynchus mykiss) model in this study. The phage was co-cultured with the virulent A. salmonicida subsp. salmonicida strain AS05 that possesses the type III secretion system (TTSS) ascV gene, and efficient bacteriolytic activity was observed against the bacteria. The administration of PAS-1 in rainbow trout demonstrated that the phage was cleared from the fish within 200 h post-administration, and a temporal neutralizing activity against the phage was detected in the sera of phage-administrated fish. The administration of PAS-1 (multiplicity of infection: 10 000) in A. salmonicida subsp. salmonicida infected rainbow trout model showed notable protective effects, with increased survival rates and mean times to death. These results demonstrated that Aeromonas phage PAS-1 could be considered as an alternative biological control agent against A. salmonicida subsp. salmonicida infections in rainbow trout culture.

  10. Step-Scan T-Cell Fourier Transform Infrared Photoacoustic Spectroscopy (FTIR-PAS) for Monitoring Environmental Air Pollutants

    NASA Astrophysics Data System (ADS)

    Liu, Lixian; Mandelis, Andreas; Melnikov, Alexander; Michaelian, Kirk; Huan, Huiting; Haisch, Christoph

    2016-07-01

    Air pollutants have adverse effects on the Earth's climate system. There is an urgent need for cost-effective devices capable of recognizing and detecting various ambient pollutants. An FTIR photoacoustic spectroscopy (FTIR-PAS) method based on a commercial FTIR spectrometer developed for air contamination monitoring will be presented. A resonant T-cell was determined to be the most appropriate resonator in view of the low-frequency requirement and space limitations in the sample compartment. Step-scan FTIR-PAS theory for regular cylinder resonator has been described as a reference for prediction of T-cell vibration principles. Both simulated amplitude and phase responses of the T-cell show good agreement with measurement data Carbon dioxide IR absorption spectra were used to demonstrate the capacity of the FTIR-PAS method to detect ambient pollutants. The theoretical detection limit for carbon dioxide was found to be 4 ppmv. A linear response to carbon dioxide concentration was found in the range from 2500 ppmv to 5000 ppmv. The results indicate that it is possible to use step-scan FTIR-PAS with a T-cell as a quantitative method for analysis of ambient contaminants.

  11. Comparison of two different passive air samplers (PUF-PAS versus SIP-PAS) to determine time-integrated average air concentration of volatile hydrophobic organic pollutants

    NASA Astrophysics Data System (ADS)

    Kim, Seung-Kyu; Park, Jong-Eun

    2014-06-01

    Despite remarkable achievements with r some chemicals, a field-measurement technique has not been advanced for volatile hydrophobic organic chemicals (HOCs) that are the subjects of international concern. This study assesses the applicability of passive air sampling (PAS) by comparing PUF-PAS and its modified SIP-PAS which was made by impregnating XAD-4 powder into PUF, overviewing the principles of PAS, screening sensitive parameters, and determining the uncertainty range of PAS-derived concentration. The PAS air sampling rate determined in this study, corrected by a co-deployed low-volume active air sampler (LAS) for neutral PFCs as model chemicals, was ˜1.2 m3 day-1. Our assessment shows that the improved sorption capacity in a SIP lengthens PAS deployment duration by expanding the linear uptake range and then enlarges the effective air sampling volume and detection frequency of chemicals at trace level. Consequently, volatile chemicals can be collected during sufficiently long times without reaching equilibrium when using SIP, while this is not possible for PUF. The most sensitive parameter to influence PAS-derived CA was an air-side mass transfer coefficient (kA), implying the necessity of spiking depuration chemicals (DCs) because this parameter is strongly related with meteorological conditions. Uncertainty in partition coefficients (KPSM-A or KOA) influences PAS-derived CA to a greater extent with regard to lower KPSM-A chemicals. Also, the PAS-derived CA has an uncertainty range of a half level to a 3-fold higher level of the calculated one. This work is expected to establish solid grounds for the improvement of field measurement technique of HOCs.

  12. Prospective randomized trial comparing pushable coil and detachable coil during percutaneous implantation of port-catheter system for hepatic artery infusion chemotherapy.

    PubMed

    Park, Sung Ii; Lee, Shin Jae; Lee, Myungsu; Lee, Mu Sook; Kim, Gyoung Min; Kim, Man Deuk; Won, Jong Yun; Lee, Do Yun

    2015-03-01

    The purpose of this study was to prospectively compare the efficacy and controllability of pushable coil and detachable coil during embolization of gastroduodenal artery (GDA) while performing percutaneous implantation of port-catheter system for hepatic artery infusion chemotherapy. Fifty patients (M:F = 42:8, age: 31-81 years) with advanced hepatocellular carcinoma undergoing port-catheter system implantation were randomized into pushable coil group and detachable coil group. During catheter fixation, GDA was embolized as close to the origin as possible. Success rate, number of coils used, number of coils removed due to malposition after deployment, time to occlusion, uncoiled GDA length, pushability, and complications were compared. Pushability was graded as no tension, slight tension, and difficult to advance. Embolization was successful in 49 patients. One failure resulted from repeated regurgitation of pushable coil into hepatic artery. Number of coils used and removed coils, time to occlusion, and uncoiled GDA length were 1-3 (mean 2.32), 5 coils in 3 patients, 4-20 min (mean 8.00), and 0-15.0 mm (mean 3.36) in pushable coil group, and 1-5 (mean 2.12), 2 coils in 2 patients, 2-15 min (mean 7.40), and 0-10.2 mm (mean 2.92) in detachable coil group, respectively, without significant difference. Pushability was no tension (n = 24) and slight tension (n = 1) in pushable coil group and no tension (n = 16), slight tension (n = 7), and difficult to advance (n = 2) in detachable coil group. One hepatic artery dissection occurred in the failed case during coil removal. Pushable coils and detachable coils had similar efficacy and controllability during GDA embolization, although there was a trend favoring detachable coil.

  13. 51. Port elevation, in port. Note reduced turtle deck due ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    51. Port elevation, in port. Note reduced turtle deck due to quarters expansion. - U.S. Coast Guard Cutter WHITE SUMAC, U.S. Coast Guard 8th District Base, 4640 Urquhart Street, New Orleans, Orleans Parish, LA

  14. Detecting Defects in Aircraft Materials by Nuclear Technique (pas)

    NASA Astrophysics Data System (ADS)

    Badawi, Emad. A.

    Positron annihilation spectroscopy (PAS) is one of the nuclear techniques used in material science. The present measurements are used to study the behavior of defect concentration in one of the most important materials aluminum alloys which is the 7075 alloy. It has been shown that positrons can become trapped at imperfect locations in solids and their mean lifetime can be influenced by changes in the concentration of such defects. No changes have been observed in the mean lifetime values after the saturation of defect concentration. The mean lifetime and trapping rates are studied for samples deformed up to 58.3%. The concentration of defect range vary from 1015 to 1018cm-3 at the thickness reduction from 2.3 to 58.3%. The dislocation density varies from 108 to 1011cm/cm3.

  15. Detecting Defects in Aircraft Materials by Nuclear Technique (pas)

    NASA Astrophysics Data System (ADS)

    Badawi, Emad. A.

    Positron annihilation spectroscopy (PAS) is one of the nuclear techniques used in material science. The present measurements are used to study the behavior of defect concentration in one of the most important materials — aluminum alloy — which is a 7075 alloy. It has been shown that positrons can become trapped in imperfect locations in solids and their mean lifetime can be influenced by changes in the concentration of such defects. No changes have been observed in the mean lifetime values after the saturation of defect concentration. The mean lifetime and trapping rates were studied for samples deformed up to 58.3%. The concentration of defect range varies (from 1015 to 1018 cm-3) at the thickness reduction, (from 2.3 to 58.3%). The range of the dislocation density varies (from 108 to 1011 cm/cm3).

  16. A history of PAs in the US Public Health Service.

    PubMed

    McKinnon, Mark F; Elizondo, Epifanio; Bonfiglio, Susan M; Hunter-Buskey, Robin N; Placide, Frances P; Bunnell, Rebecca A

    2016-12-01

    Since 1798, the men and women of the Commissioned Corps of the US Public Health Service (USPHS), one of the seven US uniformed services, have served on the front lines of public health. Two hundred years after the start of the USPHS, the first physician assistant (PA) entered the service to carry on the tradition of protecting, promoting, and advancing the health and safety of the nation. These dedicated clinicians are involved in healthcare delivery to underserved and vulnerable populations, disease control and prevention, biomedical research, food and drug regulation, and national and international response efforts for natural and man-made disasters. This article describes how PAs in the Commissioned Corps of the USPHS have impacted the health and safety of not only the United States but also the international community.

  17. Ports Primer: 7.2 Air Emissions

    EPA Pesticide Factsheets

    Near-port communities are often disproportionately impacted by air emissions due to port operations, goods movement operations and other industries that may be co-located with ports. Air emissions at ports also impact regional air quality.

  18. Ports Primer: 7.4 Agency Responsibilities

    EPA Pesticide Factsheets

    Near-port communities are often disproportionately impacted by air emissions due to port operations, goods movement operations and other industries that may be co-located with ports. Air emissions at ports also impact regional air quality.

  19. Port-wine stain

    MedlinePlus

    Early-stage port-wine stains are usually flat and pink. As the child gets older, the color may deepen to a dark red or purplish color. They occur most often on the face, but can appear anywhere on the body. Over time, ...

  20. ROCKET PORT CLOSURE

    DOEpatents

    Mattingly, J.T.

    1963-02-12

    This invention provides a simple pressure-actuated closure whereby windowless observation ports are opened to the atmosphere at preselected altitudes. The closure comprises a disk which seals a windowless observation port in rocket hull. An evacuated instrument compartment is affixed to the rocket hull adjacent the inner surface of the disk, while the outer disk surface is exposed to the atmosphere through which the rocket is traveling. The pressure differential between the evacuated instrument compartment and the relatively high pressure external atmosphere forces the disk against the edge of the observation port, thereby effecting a tight seai. The instrument compartment is evacuated to a pressure equal to the atmospheric pressure existing at the altitude at which it is desiretl that the closure should open. When the rocket reaches this preselected altitude, the inwardly directed atmospheric force on the disk is just equaled by the residual air pressure force within the instrument compartment. Consequently, the closure disk falls away and uncovers the open observation port. The separation of the disk from the rocket hull actuates a switch which energizes the mechanism of a detecting instrument disposed within the instrument compartment. (AE C)

  1. Generalized two-port elements

    NASA Astrophysics Data System (ADS)

    Tenreiro Machado, J.; Galhano, Alexandra M.

    2017-01-01

    The development of models constitutes a fundamental step in the study of natural and artificial systems. Present day science aims to address broader and more complex areas of application requiring, therefore, new concepts and models. This paper explores the concept of generalized two-port network by embedding the ideas of fractional calculus, memristor, transformer and gyrator. Each element represents separately one possible direction for generalizing the classical elements, but the cross-fertilization of the distinct topics has been overlooked. In this line of thought, the proposal of a novel element is a logical conjecture for obeying the symmetries that have been discovered in nature.

  2. 33 CFR 165.761 - Security Zones; Port of Palm Beach, Port Everglades, Port of Miami, and Port of Key West, Florida.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Ports of Palm Beach, Port Everglades, Miami or Key West, Florida. These moving security zones are... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Security Zones; Port of Palm Beach, Port Everglades, Port of Miami, and Port of Key West, Florida. 165.761 Section 165.761...

  3. Self port scanning tool : providing a more secure computing Environment through the use of proactive port scanning

    NASA Technical Reports Server (NTRS)

    Kocher, Joshua E; Gilliam, David P.

    2005-01-01

    Secure computing is a necessity in the hostile environment that the internet has become. Protection from nefarious individuals and organizations requires a solution that is more a methodology than a one time fix. One aspect of this methodology is having the knowledge of which network ports a computer has open to the world, These network ports are essentially the doorways from the internet into the computer. An assessment method which uses the nmap software to scan ports has been developed to aid System Administrators (SAs) with analysis of open ports on their system(s). Additionally, baselines for several operating systems have been developed so that SAs can compare their open ports to a baseline for a given operating system. Further, the tool is deployed on a website where SAs and Users can request a port scan of their computer. The results are then emailed to the requestor. This tool aids Users, SAs, and security professionals by providing an overall picture of what services are running, what ports are open, potential trojan programs or backdoors, and what ports can be closed.

  4. Simulation model for port shunting yards

    NASA Astrophysics Data System (ADS)

    Rusca, A.; Popa, M.; Rosca, E.; Rosca, M.; Dragu, V.; Rusca, F.

    2016-08-01

    Sea ports are important nodes in the supply chain, joining two high capacity transport modes: rail and maritime transport. The huge cargo flows transiting port requires high capacity construction and installation such as berths, large capacity cranes, respectively shunting yards. However, the port shunting yards specificity raises several problems such as: limited access since these are terminus stations for rail network, the in-output of large transit flows of cargo relatively to the scarcity of the departure/arrival of a ship, as well as limited land availability for implementing solutions to serve these flows. It is necessary to identify technological solutions that lead to an answer to these problems. The paper proposed a simulation model developed with ARENA computer simulation software suitable for shunting yards which serve sea ports with access to the rail network. Are investigates the principal aspects of shunting yards and adequate measures to increase their transit capacity. The operation capacity for shunting yards sub-system is assessed taking in consideration the required operating standards and the measure of performance (e.g. waiting time for freight wagons, number of railway line in station, storage area, etc.) of the railway station are computed. The conclusion and results, drawn from simulation, help transports and logistics specialists to test the proposals for improving the port management.

  5. Comparison of Fusion Imaging Using a Combined SPECT/CT System and Intra-arterial CT: Assessment of Drug Distribution by an Implantable Port System in Patients Undergoing Hepatic Arterial Infusion Chemotherapy

    SciTech Connect

    Ikeda, Osamu Kusunoki, Shinichiroh; Nakaura, Takeshi; Shiraishi, Shinya; Kawanaka, Kouichi; Tomiguchi, Seiji; Yamashita, Yasuyuki; Takamori, Hiroshi; Chikamoto, Akira; Kanemitsu, Keiichiro

    2006-06-15

    Hepatic arterial infusion (HAI) chemotherapy is effective for treating primary and metastatic carcinoma of the liver. We compared the perfusion patterns of HAI chemotherapy on intra-arterial port-catheter computed tomography (iapc-CT) and fused images obtained with a combined single-photon emission computed tomography/computed tomography (SPECT/CT) system. We studied 28 patients with primary or metastatic carcinoma of the liver who bore an implantable HAI port system. All underwent abdominal SPECT using Tc-99m-MAA (185 Mbq); the injection rate was 1 mL/min, identical to the chemotherapy infusion rate, and 0.5 mL/sec for iapc-CT. Delivery was through an implantable port. We compared the intrahepatic perfusion (IHP) and extrahepatic perfusion (EHP) patterns of HAI chemotherapy on iapc-CT images and fused images obtained with a combined SPECT/CT system. In 23 of 28 patients (82%), IHP patterns on iapc-CT images and fused images were identical. In 5 of the 28 patients (18%), IHP on fusion images was different from IHP on iapc-CT images. EHP was seen on fused images in 12 of the 28 patients (43%) and on iapc-CT images in 8 patients (29%). In 17 patients (61%), upper gastrointestinal endoscopy revealed gastroduodenal mucosal lesions. EHP was revealed on fused images in 10 of these patients; 9 of them manifested gastroduodenal toxicity at the time of subsequent HAI chemotherapy. Fusion imaging using the combined SPECT/CT system reflects the actual distribution of the infused anticancer agent. This information is valuable not only for monitoring adequate drug distribution but also for avoiding potential extrahepatic complications.

  6. Robotics for port security

    NASA Astrophysics Data System (ADS)

    Smuda, William; Freiburger, Lonnie A.; Gerhart, Grant R.; Mallon, Lawrence

    2004-09-01

    The capacity through the use of robots with on board visual, NBC and HAZMAT sensors to rapidly and continuously screen convoys and staged exposed assets would be a force multiplier and measurably improve base and force protection at both inbound and outbound DOD and commercial facilities. This paper chronicles our experiment with the ODIS robot at the Ports of Los Angeles (POLA) and Long Beach (POLB) in July of 2003. POLA & POLB are responsible for moving over 30% of the United States trade goods. Queues of 54" container trucks routinely exceed 100 trucks, extending for over a mile from the port entrances. Spotted equipment and convoys at staging areas are a high visibility and value assets to a terrorist incident. The POLA/POLB scenario is also representative of TRANSCOM operations at the port of Basra during current operation in Iraq. The California Highway Patrol is responsible for physically inspecting these vehicles for roadworthiness and contraband, a dangerous and dirty job. We will also discuss the use of ODIS robots for this task.

  7. Central Vein Dilatation Prior to Concomitant Port Implantation

    SciTech Connect

    Krombach, Gabriele A. Plumhans, Cedric; Goerg, Fabian; Guenther, Rolf W.

    2010-04-15

    Implantation of subcutaneous port systems is routinely performed in patients requiring repeated long-term infusion therapy. Ultrasound- and fluoroscopy-guided implantation under local anesthesia is broadly established in interventional radiology and has decreased the rate of complications compared to the surgical approach. In addition, interventional radiology offers the unique possibility of simultaneous management of venous occlusion. We present a technique for recanalization of central venous occlusion and angioplasty combined with port placement in a single intervention which we performed in two patients. Surgical port placement was impossible owing to occlusion of the superior vena cava following placement of a cardiac pacemaker and occlusion of multiple central veins due to paraneoplastic coagulopathy, respectively. In both cases the affected vessel segments were dilated with balloon catheters and the port systems were placed thereafter. After successful dilatation, the venous access was secured with a 25-cm-long, 8-Fr introducer sheath, a subcutaneous pocket prepared, and the port catheter tunneled to the venipuncture site. The port catheter was introduced through the sheath with the proximal end connected to a 5-Fr catheter. This catheter was pulled through the tunnel in order to preserve the tunnel and, at the same time, allow safe removal of the long sheath over the wire. The port system functioned well in both cases. The combination of recanalization and port placement in a single intervention is a straightforward alternative for patients with central venous occlusion that can only be offered by interventional radiology.

  8. Patient-specific port placement for laparoscopic surgery using atlas-based registration

    NASA Astrophysics Data System (ADS)

    Enquobahrie, Andinet; Shivaprabhu, Vikas; Aylward, Stephen; Finet, Julien; Cleary, Kevin; Alterovitz, Ron

    2013-03-01

    Laparoscopic surgery is a minimally invasive surgical approach, in which abdominal surgical procedures are performed through trocars via small incisions. Patients benefit by reduced postoperative pain, shortened hospital stays, improved cosmetic results, and faster recovery times. Optimal port placement can improve surgeon dexterity and avoid the need to move the trocars, which would cause unnecessary trauma to the patient. We are building an intuitive open source visualization system to help surgeons identify ports. Our methodology is based on an intuitive port placement visualization module and atlas-based registration algorithm to transfer port locations to individual patients. The methodology follows three steps:1) Use a port placement visualization module to manually place ports in an abdominal organ atlas. This step generates port-augmented abdominal atlas. This is done only once for a given patient population. 2) Register the atlas data with the patient CT data, to transfer the prescribed ports to the individual patient 3) Review and adjust the transferred port locations using the port placement visualization module. Tool maneuverability and target reachability can be tested using the visualization system. Our methodology would decrease the amount of physician input necessary to optimize port placement for each patient case. In a follow up work, we plan to use the transferred ports as starting point for further optimization of the port locations by formulating a cost function that will take into account factors such as tool dexterity and likelihood of collision between instruments.

  9. Sewage Disposal in Port Harcourt, Nigeria.

    ERIC Educational Resources Information Center

    Ayotamuno, M. J.

    1993-01-01

    This survey of the Port Harcourt, Nigeria, sewage disposal system exemplifies sewage disposal in the developing world. Results reveal that some well-constructed and maintained drains, as well as many open drains and septic tanks, expose women and children to the possibility of direct contact with parasitic organisms and threaten water resources.…

  10. Ligand-binding PAS domains in a genomic, cellular, and structural context.

    PubMed

    Henry, Jonathan T; Crosson, Sean

    2011-01-01

    Per-Arnt-Sim (PAS) domains occur in proteins from all kingdoms of life. In the bacterial kingdom, PAS domains are commonly positioned at the amino terminus of signaling proteins such as sensor histidine kinases, cyclic-di-GMP synthases/hydrolases, and methyl-accepting chemotaxis proteins. Although these domains are highly divergent at the primary sequence level, the structures of dozens of PAS domains across a broad section of sequence space have been solved, revealing a conserved three-dimensional architecture. An all-versus-all alignment of 63 PAS structures demonstrates that the PAS domain family forms structural clades on the basis of two principal variables: (a) topological location inside or outside the plasma membrane and (b) the class of small molecule that they bind. The binding of a chemically diverse range of small-molecule metabolites is a hallmark of the PAS domain family. PAS ligand binding either functions as a primary cue to initiate a cellular signaling response or provides the domain with the capacity to respond to secondary physical or chemical signals such as gas molecules, redox potential, or photons. This review synthesizes the current state of knowledge of the structural foundations and evolution of ligand recognition and binding by PAS domains.

  11. An oxidative N-demethylase reveals PAS transition from ubiquitous sensor to enzyme.

    PubMed

    Ortmayer, Mary; Lafite, Pierre; Menon, Binuraj R K; Tralau, Tewes; Fisher, Karl; Denkhaus, Lukas; Scrutton, Nigel S; Rigby, Stephen E J; Munro, Andrew W; Hay, Sam; Leys, David

    2016-11-24

    The universal Per-ARNT-Sim (PAS) domain functions as a signal transduction module involved in sensing diverse stimuli such as small molecules, light, redox state and gases. The highly evolvable PAS scaffold can bind a broad range of ligands, including haem, flavins and metal ions. However, although these ligands can support catalytic activity, to our knowledge no enzymatic PAS domain has been found. Here we report characterization of the first PAS enzyme: a haem-dependent oxidative N-demethylase. Unrelated to other amine oxidases, this enzyme contains haem, flavin mononucleotide, 2Fe-2S and tetrahydrofolic acid cofactors, and specifically catalyses the NADPH-dependent oxidation of dimethylamine. The structure of the α subunit reveals that it is a haem-binding PAS domain, similar in structure to PAS gas sensors. The dimethylamine substrate forms part of a highly polarized oxygen-binding site, and directly assists oxygen activation by acting as both an electron and proton donor. Our data reveal that the ubiquitous PAS domain can make the transition from sensor to enzyme, suggesting that the PAS scaffold can support the development of artificial enzymes.

  12. Ligand binding PAS domains in a genomic, cellular, and structural context

    PubMed Central

    Henry, Jonathan T.; Crosson, Sean

    2012-01-01

    Per-Arnt-Sim (PAS) domains occur in proteins from all kingdoms of life. In the bacterial kingdom, PAS domains are commonly positioned at the amino terminus of signaling proteins such as sensor histidine kinases, cyclic-di-GMP synthases/hydrolases, and methyl-accepting chemotaxis proteins. Although these domains are highly divergent at the primary sequence level, the structures of dozens of PAS domains across a broad section of sequence space have been solved, revealing a conserved three-dimensional architecture. An all-versus-all alignment of 63 PAS structures demonstrates that the PAS domain family forms structural clades on the basis of two principal variables: (a) topological location inside or outside the plasma membrane and (b) the class of small molecule that they bind. The binding of a chemically diverse range of small-molecule metabolites is a hallmark of the PAS domain family. PAS ligand binding either functions as a primary cue to initiate a cellular signaling response or provides the domain with the capacity to respond to secondary physical or chemical signals such as gas molecules, redox potential, or photons. This review synthesizes the current state of knowledge of the structural foundations and evolution of ligand recognition and binding by PAS domains. PMID:21663441

  13. Successful control of central nervous system bleeding in two newborns with severe factor VII deficiency using rFVIIa administered via Port-a-Cath.

    PubMed

    Karimi, Mehran

    2008-04-01

    We report two cases of newborn infants (15 and 20 days old, respectively; both were full-term infants with normal vaginal deliveries) with severe factor VII (FVII) deficiencies (FVII <1%) who presented with convulsions and poor feeding. Brain sonography and computed tomography scan showed intracranial hemorrhage. Prothrombin time (PT) was severely prolonged, but partial thromboplastin time, platelet count, and bleeding time were normal. FVII assay showed that both infants had FVII levels of less than 1%. Treatment with recombinant activated factor VII (rFVIIa; NovoSeven(((R))), Novo Nordisk, Bagsvaerd, Denmark) was deemed necessary. We started rFVIIa therapy with 20 microg/kg administered intravenously (IV) every 6 hours for 2 to 3 days. This treatment schedule resulted in normalization of PT, control of convulsions, and reduction in central nervous system (CNS) bleeding. Although prophylaxis is currently an off-label use of rFVIIa, the patients then received one IV bolus dose of 20 microg/kg every other day as a prophylaxis regimen, but the symptoms recurred in one patient a few days later. Therefore, we increased the dose to 30 microg/kg IV every 4 hours, and this led to control of convulsions and CNS bleeding. This patient received rFVIIa at a dose of 30 microg/kg every other day via Port-a-Cath (Bistric ATH, France) due to poor venous access. His parents were educated in the use of the Port-a-Cath, and the patient received home treatment with rFVIIa (30 microg/kg IV every other day and then twice per week) for 6 months. He had a normal neurological status at this time. Unfortunately, at the age of 6 months, this infant died from severe post-traumatic CNS bleeding when he was 60 km away from our center. The second patient, who also received prophylactic rFVIIa at a dose of 20 microg/kg every other day with gradual prolongation of the dose interval to once per week, is currently in good condition with a mild neurological deficit caused by repeated CNS bleedings

  14. 48 CFR 47.303-12 - Ex dock, pier, or warehouse, port of importation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... warehouse, port of importation. 47.303-12 Section 47.303-12 Federal Acquisition Regulations System FEDERAL..., pier, or warehouse, port of importation. (a) Explanation of delivery term. Ex dock, pier, or warehouse... in the warehouse at the specified port of importation. (b) Contractor responsibilities....

  15. 48 CFR 47.303-9 - F.o.b. vessel, port of shipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false F.o.b. vessel, port of... CONTRACT MANAGEMENT TRANSPORTATION Transportation in Supply Contracts 47.303-9 F.o.b. vessel, port of shipment. (a) Explanation of delivery term. F.o.b. vessel, port shipment means free of expense to...

  16. 48 CFR 47.303-9 - F.o.b. vessel, port of shipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false F.o.b. vessel, port of... CONTRACT MANAGEMENT TRANSPORTATION Transportation in Supply Contracts 47.303-9 F.o.b. vessel, port of shipment. (a) Explanation of delivery term. F.o.b. vessel, port shipment means free of expense to...

  17. 48 CFR 52.247-37 - F.o.b. Vessel, Port of Shipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false F.o.b. Vessel, Port of....247-37 F.o.b. Vessel, Port of Shipment. As prescribed in 47.303-9(c), insert the following clause in solicitations and contracts when the delivery term is f.o.b. vessel, port of shipment: F.o.b. Vessel, Port...

  18. 48 CFR 52.247-37 - F.o.b. Vessel, Port of Shipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Vessel, Port of....247-37 F.o.b. Vessel, Port of Shipment. As prescribed in 47.303-9(c), insert the following clause in solicitations and contracts when the delivery term is f.o.b. vessel, port of shipment: F.o.b. Vessel, Port...

  19. 33 CFR 149.413 - On a manned deepwater port, what spaces require a fixed fire extinguishing system?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... fixed gaseous or other approved fixed-type extinguishing system. (a) Paint lockers with a carrying capacity of more than 200 cubic feet, and similar spaces containing flammable liquids. (b) Galley ranges...

  20. 33 CFR 149.413 - On a manned deepwater port, what spaces require a fixed fire extinguishing system?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... fixed gaseous or other approved fixed-type extinguishing system. (a) Paint lockers with a carrying capacity of more than 200 cubic feet, and similar spaces containing flammable liquids. (b) Galley ranges...

  1. 33 CFR 149.413 - On a manned deepwater port, what spaces require a fixed fire extinguishing system?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... fixed gaseous or other approved fixed-type extinguishing system. (a) Paint lockers with a carrying capacity of more than 200 cubic feet, and similar spaces containing flammable liquids. (b) Galley ranges...

  2. 33 CFR 149.413 - On a manned deepwater port, what spaces require a fixed fire extinguishing system?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... fixed gaseous or other approved fixed-type extinguishing system. (a) Paint lockers with a carrying capacity of more than 200 cubic feet, and similar spaces containing flammable liquids. (b) Galley ranges...

  3. 33 CFR 149.413 - On a manned deepwater port, what spaces require a fixed fire extinguishing system?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... fixed gaseous or other approved fixed-type extinguishing system. (a) Paint lockers with a carrying capacity of more than 200 cubic feet, and similar spaces containing flammable liquids. (b) Galley ranges...

  4. In vivo photoacoustic imaging of model of port wine stains.

    PubMed

    Yuan, Kaihua; Yuan, Yi; Gu, Ying; Gao, Jianhua; Xing, Da

    2012-01-01

    Port wine stains are categorized as a benign capillary vascular malformation, which is hard to cure. In this paper, a photoacoustic microscopy system, which integrated a two-dimensional scanning galvanometer, an objective lens and a focused ultrasound transducer, was designed for noninvasive imaging of blood vessels of port wine stains model in vivo. Cock comb was chosen as the port wine stains model in the experiment. The blood vessels in x-y plane and x-z plane were imaged clearly. Experimental results demonstrate that photoacoustic microscopy can image the blood vessels of port wine stains model in vivo with high contrast and high resolution. It has the potential for clinical applications in detecting the blood vessels in port wine stains skin.

  5. A procedure for identifying significant environmental aspects in sea ports.

    PubMed

    Darbra, R M; Ronza, A; Stojanovic, T A; Wooldridge, C; Casal, J

    2005-08-01

    A new methodology has been designed to identify and rank the significant environmental aspects in sea ports. The main objective of the Strategic Overview of Significant Environmental Aspects (SOSEA) is to help port managers to identify significant environmental aspects and to reinforce the awareness about them in order to prioritise work in environmental management. Developed in close collaboration with port environmental managers and tested in a set of ports, it is a user-friendly tool that can be applied in approximately half a working day. It is based on ISO 14001 vocabulary and requirements and it can be considered as the base for the implementation of any Environmental Management System for port communities.

  6. A programmable and configurable multi-port System-on-Chip for stimulating electrokinetically-driven microfluidic devices.

    PubMed

    Lopez, Martha Salome; Gerstlauer, Andreas; Avila, Alfonso; Martinez-Chapa, Sergio O

    2011-01-01

    Recent research has demonstrated the use of microfluidic devices and electro-kinetics in areas such as medicine, genetics, embryology, epidemiology and pollution analysis, where manipulation of particles suspended in liquid media is required. Micro-fabrication technology has made it possible to increase system complexity and functionality by allowing integration of different processing and analysis stages in a single chip. However, fully integrated and autonomous microfluidic systems supporting ad-hoc stimulation have yet to be developed. This paper presents a flexible, configurable and programmable stimulator for electro-kinetically driven microfluidic devices. The stimulator is a dedicated System-on-Chip (SoC) architecture that generates sine, triangle, and sawtooth signals within a frequency range of 1 Hz to 20 MHz, capable of delivering single, dual, and superimposed waveforms, in a user defined test sequence for a selected time period. The system is designed to be integrated into complete, autonomous Lab-on-Chip, portable or implantable devices. As such, it is expected to help significantly advance current and future research on particle manipulation.

  7. A PAS domain-containing regulator controls flagella-flagella interactions in Campylobacter jejuni

    PubMed Central

    Reuter, Mark; Periago, Paula M.; Mulholland, Francis; Brown, Helen L.; van Vliet, Arnoud H. M.

    2015-01-01

    The bipolar flagella of the foodborne bacterial pathogen Campylobacter jejuni confer motility, which is essential for virulence. The flagella of C. jejuni are post-translationally modified, but how this process is controlled is not well understood. In this work, we have identified a novel PAS-domain containing regulatory system, which modulates flagella-flagella interactions in C. jejuni. Inactivation of the cj1387c gene, encoding a YheO-like PAS6 domain linked to a helix-turn-helix domain, resulted in the generation of a tightly associated “cell-train” morphotype, where up to four cells were connected by their flagella. The morphotype was fully motile, resistant to vortexing, accompanied by increased autoagglutination, and was not observed in aflagellated cells. The Δcj1387c mutant displayed increased expression of the adjacent Cj1388 protein, which comprises of a single endoribonuclease L-PSP domain. Comparative genomics showed that cj1387c (yheO) orthologs in bacterial genomes are commonly linked to an adjacent cj1388 ortholog, with some bacteria, including C. jejuni, containing another cj1388-like gene (cj0327). Inactivation of the cj1388 and cj0327 genes resulted in decreased autoagglutination in Tween-20-supplemented media. The Δcj1388 and Δcj0327 mutants were also attenuated in a Galleria larvae-based infection model. Finally, substituting the sole cysteine in Cj1388 for serine prevented Cj1388 dimerization in non-reducing conditions, and resulted in decreased autoagglutination in the presence of Tween-20. We hypothesize that Cj1388 and Cj0327 modulate post-translational modification of the flagella through yet unidentified mechanisms, and propose naming Cj1387 the Campylobacter Flagella Interaction Regulator CfiR, and the Cj1388 and Cj0327 protein as CfiP and CfiQ, respectively. PMID:26284050

  8. The Development and Clinical Use of a Beam ON-LINE PET System Mounted on a Rotating Gantry Port in Proton Therapy

    SciTech Connect

    Nishio, Teiji; Miyatake, Aya; Ogino, Takashi; Nakagawa, Keiichi; Saijo, Nagahiro; Esumi, Hiroyasu

    2010-01-15

    Purpose: To verify the usefulness of our developed beam ON-LINE positron emission tomography (PET) system mounted on a rotating gantry port (BOLPs-RGp) for dose-volume delivery-guided proton therapy (DGPT). Methods and Materials: In the proton treatment room at our facility, a BOLPs-RGp was constructed so that a planar PET apparatus could be mounted with its field of view covering the iso-center of the beam irradiation system. Activity measurements were performed in 48 patients with tumors of the head and neck, liver, lungs, prostate, and brain. The position and intensity of the activity were measured using the BOLPs-RGp during the 200 s immediately after the proton irradiation. Results: The daily measured activity images acquired by the BOLPs-RGp showed the proton irradiation volume in each patient. Changes in the proton-irradiated volume were indicated by differences between a reference activity image (taken at the first treatment) and the daily activity-images. In the case of head-and-neck treatment, the activity distribution changed in the areas where partial tumor reduction was observed. In the case of liver treatment, it was observed that the washout effect in necrotic tumor cells was slower than in non-necrotic tumor cells. Conclusions: The BOLPs-RGp was developed for the DGPT. The accuracy of proton treatment was evaluated by measuring changes of daily measured activity. Information about the positron-emitting nuclei generated during proton irradiation can be used as a basis for ensuring the high accuracy of irradiation in proton treatment.

  9. Asymmetric sound transmission in a passive non-blocking structure with multiple ports

    NASA Astrophysics Data System (ADS)

    Zhu, Yi-Fan; Gu, Zhong-Ming; Liang, Bin; Yang, Jing; Yang, Jun; Yin, Lei-lei; Cheng, Jian-Chun

    2016-09-01

    We present the mechanism for breaking the symmetry in sound transmission between any two neighboring ports in a passive multi-port system. Numerical simulations and experimental measurements verify that by using judiciously designed metastructures to provide an extra wavevector without blocking the sound path, the propagating wave will travel along a preset direction at each port instead of splitting to both directions. We have also demonstrated the flexibility of this scheme to adjust the location of each port. Our design advances further the concept of one-way manipulation in passive two-port systems and may enable novel sound-steering devices for more versatile applications.

  10. Changes at the KinA PAS-A Dimerization Interface Influence Histidine Kinase Function

    SciTech Connect

    Lee, James; Tomchick, Diana R.; Brautigam, Chad A.; Machius, Mischa; Kort, Remco; Hellingwerf, Klaas J.; Gardner, Kevin H.

    2008-11-12

    The Bacillus subtilis KinA protein is a histidine protein kinase that controls the commitment of this organism to sporulate in response to nutrient deprivation and several other conditions. Prior studies indicated that the N-terminal Per-ARNT-Sim domain (PAS-A) plays a critical role in the catalytic activity of this enzyme, as demonstrated by the significant decrease of the autophosphorylation rate of a KinA protein lacking this domain. On the basis of the environmental sensing role played by PAS domains in a wide range of proteins, including other bacterial sensor kinases, it has been suggested that the PAS-A domain plays an important regulatory role in KinA function. We have investigated this potential by using a combination of biophysical and biochemical methods to examine PAS-A structure and function, both in isolation and within the intact protein. Here, we present the X-ray crystal structure of the KinA PAS-A domain, showing that it crystallizes as a homodimer using {beta}-sheet/{beta}-sheet packing interactions as observed for several other PAS domain complexes. Notably, we observed two dimers with tertiary and quaternary structure differences in the crystalline lattice, indicating significant structural flexibility in these domains. To confirm that KinA PAS-A also forms dimers in solution, we used a combination of NMR spectroscopy, gel filtration chromatography, and analytical ultracentrifugation, the results of which are all consistent with the crystallographic results. We experimentally tested the importance of several residues at the dimer interface using site-directed mutagenesis, finding changes in the PAS-A domain that significantly alter KinA enzymatic activity in vitro and in vivo. These results support the importance of PAS domains within KinA and other histidine kinases and suggest possible routes for natural or artificial regulation of kinase activity.

  11. Optimization for Hub-and-Spoke Port Logistics Network of Dynamic Hinterland

    NASA Astrophysics Data System (ADS)

    Ming-Jun, Ji; Yan-Ling, Chu

    The port logistics and its regional economic react on each other and develop in unison. This paper studies the Hub-and-Spoke port logistics network which is a transportation system between the sea routes and ports hinterland transport routes. An optimization model is proposed with the objective of the total transportation cost in the regional port group based on the conditions of dynamic hinterland. This paper not only ensures every port in the hub-and spoke port logistics network to achieve its maximum economic benefits, but also makes the entire system get the minimum total transportation cost in the view of quantitative point. In order to illustrate the validity of the model, the example was solved. The results show that the model is feasible. Furthermore, the competitiveness power of the port, the demarcation of hinterland and the traffic capacity are changed dynamically in the model, which is closer to the real system.

  12. Placement of a subdural evacuating port system for management of iatrogenic hyperacute subdural hemorrhage following intracranial monitor placement.

    PubMed

    Ivan, Michael E; Nathan, Jay K; Manley, Geoffery T; Huang, Michael C

    2013-12-01

    A 22-year-old man was admitted with a severe traumatic brain injury developed a hyperacute subdural hematoma (SDH) following attempted brain tissue oxygen monitor placement. This patient was successfully treated by placement of a subdural evacuation portal system (SEPS). The patient presented to a Level I trauma center after a severe bike versus auto accident. On admission, he was found to have a Glasgow Coma Scale (GCS) score of 3. The patient had small areas of intraparechymal hemorrhage as well as suspicion for diffuse axonal injury in the midbrain. Based on the patient's GCS score, neurological monitoring was indicated as a part of his intensive care unit treatment, however a SDH occurred during an attempted placement of a brain tissue oxygen monitor. This iatrogenic hyperacute SDH after burr hole monitoring device placement was treated with a SEPS drain. The SEPS drain has been shown to provide complete and/or temporary decompression of liquefied SDH. To our knowledge, this is the first report of using the SEPS to treat iatrogenic SDH associated with an intracranial monitoring device. This technique should be added to the armament of treatment options for a neurosurgeon to treat or temporize a hyperacute SDH with increased intracranial pressure in specific patients.

  13. A multi-port power electronics interface for battery powered electric vehicles: Application of inductively coupled wireless power transfer and hybrid energy storage system

    NASA Astrophysics Data System (ADS)

    McDonough, Matthew Kelly

    Climate change, pollution, and geopolitical conflicts arising from the extreme wealth concentrations caused by fossil fuel deposits are just a few of the side-effects of the way that we fuel our society. A new method to power our civilization is becoming more and more necessary. Research for new, more sustainable fuel sources is already underway due to research in wind, solar, geothermal, and hydro power. However this focus is mainly on stationary applications. A large portion of fossil fuel usage comes from transportation. Unfortunately, the transition to cleaner transportation fuels is being stunted by the inability to store adequate amounts of energy in electro-chemical batteries. The idea of charging while driving has been proposed by many researchers, however several challenges still exist. In this work some of these challenges are addressed. Specifically, the ability to route power from multiple sources/loads is investigated. Special attention is paid to adjusting the time constant of particular converters, namely the battery and ultra-capacitor converters to reduce the high frequency and high magnitude current components applied to the battery terminals. This is done by developing a closed loop model of the entire multi-port converter, including the state of charge of the ultra-capacitors. The development of closed loop models and two experimental testbeds for use as stationary vehicle charging platforms with their unique set of sources/loads are presented along-side an on-board charger to demonstrate the similarities and differences between stationary charging and mobile charging. Experimental results from each are given showing that it is not only possible, but feasible to utilize Inductively Coupled Wireless Power Transfer (ICWPT) to charge a battery powered electric vehicle while driving and still protect the life-span of the batteries under the new, harsher conditions generated by the ICWPT system.

  14. H2O2 production rate in Lactobacillus johnsonii is modulated via the interplay of a heterodimeric flavin oxidoreductase with a soluble 28 Kd PAS domain containing protein

    PubMed Central

    Valladares, Ricardo B.; Graves, Christina; Wright, Kaitlyn; Gardner, Christopher L.; Lorca, Graciela L.; Gonzalez, Claudio F.

    2015-01-01

    Host and commensals crosstalk, mediated by reactive oxygen species (ROS), has triggered a growing scientific interest to understand the mechanisms governing such interaction. However, the majority of the scientific studies published do not evaluate the ROS production by commensals bacteria. In this context we recently showed that Lactobacillus johnsonii N6.2, a strain of probiotic value, modulates the activity of the critical enzymes 2,3-indoleamine dioxygenase via H2O2 production. L. johnsonii N6.2 by decreasing IDO activity, is able to modify the tryptophan/kynurenine ratio in the host blood with further systemic consequences. Understanding the mechanisms of H2O2 production is critical to predict the probiotic value of these strains and to optimize bacterial biomass production in industrial processes. We performed a transcriptome analysis to identify genes differentially expressed in L. johnsonii N6.2 cells collected from cultures grown under different aeration conditions. Herein we described the biochemical characteristics of a heterodimeric FMN reductase (FRedA/B) whose in vitro activity is controlled by LjPAS protein with a typical Per-Arnst-Sim (PAS) sensor domain. Interestingly, LjPAS is fused to the FMN reductase domains in other lactobacillaceae. In L. johnsonii, LjPAS is encoded by an independent gene which expression is repressed under anaerobic conditions (>3 fold). Purified LjPAS was able to slow down the FRedA/B initial activity rate when the holoenzyme precursors (FredA, FredB, and FMN) were mixed in vitro. Altogether the results obtained suggest that LjPAS module regulates the H2O2 production helping the cells to minimize oxidative stress in response to environmental conditions. PMID:26236298

  15. Glove port retrofit assembly and method of replacing components

    DOEpatents

    Giesen, Isaac M; Cournoyer, Michael E; Rael, David G

    2014-11-18

    What is disclosed is a system for retrofitting a sealed enclosure for performing work therein having an outer enclosure assembly configured to be clamped to the outer annular face of a port ring and form a sealed engagement with the outer annular surface of the port ring, a change assembly having an inner ring and an access element wherein the inner ring has a first annular cylinder body that is sized to be slidably received by the port ring and the access element is configured to be sealably and slidably positioned within the first annular cylinder body of the inner ring.

  16. PAS-cal: a Generic Recombinant Peptide Calibration Standard for Mass Spectrometry

    NASA Astrophysics Data System (ADS)

    Breibeck, Joscha; Serafin, Adam; Reichert, Andreas; Maier, Stefan; Küster, Bernhard; Skerra, Arne

    2014-08-01

    We describe the design, preparation, and mass-spectrometric characterization of a new recombinant peptide calibration standard with uniform biophysical and ionization characteristics for mass spectrometry. "PAS-cal" is an artificial polypeptide concatamer of peptide cassettes with varying lengths, each composed of the three small, chemically stable amino acids Pro, Ala, and Ser, which are interspersed by Arg residues to allow site-specific cleavage with trypsin. PAS-cal is expressed at high yields in Escherichia coli as a Small Ubiquitin-like MOdifier (SUMO) fusion protein, which is easily purified and allows isolation of the PAS-cal moiety after SUMO protease cleavage. Upon subsequent in situ treatment with trypsin, the PAS-cal polypeptide yields a set of four defined homogeneous peptides in the range from 2 to 8 kDa with equal mass spacing. ESI-MS analysis revealed a conveniently interpretable raw spectrum, which after deconvolution resulted in a very simple pattern of four peaks with similar ionization signals. MALDI-MS analysis of a PAS-cal peptide mixture comprising both the intact polypeptide and its tryptic fragments revealed not only the four standard peptides but also the singly and doubly charged states of the intact concatamer as well as di- and trimeric adduct ion species between the peptides, thus augmenting the observable m/z range. The advantageous properties of PAS-cal are most likely a result of the strongly hydrophilic and conformationally disordered PEG-like properties of the PAS sequences. Therefore, PAS-cal offers an inexpensive and versatile recombinant peptide calibration standard for mass spectrometry in protein/peptide bioanalytics and proteomics research, the composition of which may be further adapted to fit individual needs.

  17. Characterization of the near-source population around five candidate ports on the Eastern Seaboard and Gulf Coast using a multi-modal freight transport perspective

    EPA Science Inventory

    Many ports are currently preparing for increased freight traffic, which may result in elevated local air pollution in areas near the port and freight transportation corridors. In this study, a geographical information system (GIS) analysis of areas surrounding five portsPort o...

  18. PerPAS: Topology-Based Single Sample Pathway Analysis Method.

    PubMed

    Liu, Chengyu; Lehtonen, Rainer; Hautaniemi, Sampsa

    2017-03-08

    Identification of intracellular pathways that play key roles in cancer progression and drug resistance is a prerequisite for developing targeted cancer treatments. The era of personalized medicine calls for computational methods that can function with one sample or very small set of samples. Developing such methods is challenging because standard statistical approaches pose several limiting assumptions, such as number of samples, that prevent their application when n approaches to one. We have developed a novel pathway analysis method called PerPAS to estimate pathway activity at a single sample level by integrating pathway topology and transcriptomics data. In addition, PerPAS is able to identify altered pathways between cancer and control samples as well as to identify key nodes that contribute to the pathway activity. In our case study using breast cancer data, we show that PerPAS can identify highly altered pathways that are associated with patient survival. PerPAS identified four pathways that were associated with patient survival and were successfully validated in three independent breast cancer cohorts. In comparison to two other pathway analysis methods that function at a single sample level, PerPAS had superior performance in both synthetic and breast cancer expression datasets. PerPAS is a free R package (http://csbi.ltdk.helsinki.fi/pub/czliu/perpas/).

  19. A gigapixel commercially manufactured cryogenic camera for the J-PAS 2.5m survey telescope

    NASA Astrophysics Data System (ADS)

    Jorden, P. R.; Bastable, M.; Clapp, M.; Darby, S.; Dryer, M.; Eaton, T.; Fenemore-Jones, G.; Jerram, P.; Marin-Franch, A.; Palmer, I.; Pittock, R.; Pool, P.; Rennshaw, R.; Taylor, K.; Waltham, N.; Wheeler, P.

    2012-07-01

    The J-PAS (Javalambre Physics-of-the-Accelerating-Universe Astrophysical Survey) project will perform a five-year survey of the northern sky from a new 2.5m telescope in Teruel, Spain. We describe the design concept of a complete cryogenic camera with a mosaic focal plane and 1.2 gigapixel science array which is to be commercially supplied. The focal plane is contained within a novel liquid-nitrogen-cooled vacuum cryostat, with proximity drive electronics designed to achieve a 4 e- readout noise from the 224-channel CCD system.

  20. The PAS Domain-Containing Protein HeuR Regulates Heme Uptake in Campylobacter jejuni

    PubMed Central

    Gaddy, Jennifer A.

    2016-01-01

    ABSTRACT Campylobacter jejuni is a leading cause of bacterially derived gastroenteritis. A previous mutant screen demonstrated that the heme uptake system (Chu) is required for full colonization of the chicken gastrointestinal tract. Subsequent work identified a PAS domain-containing regulator, termed HeuR, as being required for chicken colonization. Here we confirm that both the heme uptake system and HeuR are required for full chicken gastrointestinal tract colonization, with the heuR mutant being particularly affected during competition with wild-type C. jejuni. Transcriptomic analysis identified the chu genes—and those encoding other iron uptake systems—as regulatory targets of HeuR. Purified HeuR bound the chuZA promoter region in electrophoretic mobility shift assays. Consistent with a role for HeuR in chu expression, heuR mutants were unable to efficiently use heme as a source of iron under iron-limiting conditions, and mutants exhibited decreased levels of cell-associated iron by mass spectrometry. Finally, we demonstrate that an heuR mutant of C. jejuni is resistant to hydrogen peroxide and that this resistance correlates to elevated levels of catalase activity. These results indicate that HeuR directly and positively regulates iron acquisition from heme and negatively impacts catalase activity by an as yet unidentified mechanism in C. jejuni. PMID:27935836

  1. Cache Domains That are Homologous to, but Different from PAS Domains Comprise the Largest Superfamily of Extracellular Sensors in Prokaryotes.

    PubMed

    Upadhyay, Amit A; Fleetwood, Aaron D; Adebali, Ogun; Finn, Robert D; Zhulin, Igor B

    2016-04-01

    Cellular receptors usually contain a designated sensory domain that recognizes the signal. Per/Arnt/Sim (PAS) domains are ubiquitous sensors in thousands of species ranging from bacteria to humans. Although PAS domains were described as intracellular sensors, recent structural studies revealed PAS-like domains in extracytoplasmic regions in several transmembrane receptors. However, these structurally defined extracellular PAS-like domains do not match sequence-derived PAS domain models, and thus their distribution across the genomic landscape remains largely unknown. Here we show that structurally defined extracellular PAS-like domains belong to the Cache superfamily, which is homologous to, but distinct from the PAS superfamily. Our newly built computational models enabled identification of Cache domains in tens of thousands of signal transduction proteins including those from important pathogens and model organisms. Furthermore, we show that Cache domains comprise the dominant mode of extracellular sensing in prokaryotes.

  2. Cache domains that are homologous to, but different from PAS domains comprise the largest superfamily of extracellular sensors in prokaryotes

    DOE PAGES

    Upadhyay, Amit A.; Fleetwood, Aaron D.; Adebali, Ogun; ...

    2016-04-06

    Cellular receptors usually contain a designated sensory domain that recognizes the signal. Per/Arnt/Sim (PAS) domains are ubiquitous sensors in thousands of species ranging from bacteria to humans. Although PAS domains were described as intracellular sensors, recent structural studies revealed PAS-like domains in extracytoplasmic regions in several transmembrane receptors. However, these structurally defined extracellular PAS-like domains do not match sequence-derived PAS domain models, and thus their distribution across the genomic landscape remains largely unknown. Here we show that structurally defined extracellular PAS-like domains belong to the Cache superfamily, which is homologous to, but distinct from the PAS superfamily. Our newly builtmore » computational models enabled identification of Cache domains in tens of thousands of signal transduction proteins including those from important pathogens and model organisms.Moreover, we show that Cache domains comprise the dominant mode of extracellular sensing in prokaryotes.« less

  3. Cache domains that are homologous to, but different from PAS domains comprise the largest superfamily of extracellular sensors in prokaryotes

    SciTech Connect

    Upadhyay, Amit A.; Fleetwood, Aaron D.; Adebali, Ogun; Finn, Robert D.; Zhulin, Igor B.; Schlessinger, Avner

    2016-04-06

    Cellular receptors usually contain a designated sensory domain that recognizes the signal. Per/Arnt/Sim (PAS) domains are ubiquitous sensors in thousands of species ranging from bacteria to humans. Although PAS domains were described as intracellular sensors, recent structural studies revealed PAS-like domains in extracytoplasmic regions in several transmembrane receptors. However, these structurally defined extracellular PAS-like domains do not match sequence-derived PAS domain models, and thus their distribution across the genomic landscape remains largely unknown. Here we show that structurally defined extracellular PAS-like domains belong to the Cache superfamily, which is homologous to, but distinct from the PAS superfamily. Our newly built computational models enabled identification of Cache domains in tens of thousands of signal transduction proteins including those from important pathogens and model organisms.Moreover, we show that Cache domains comprise the dominant mode of extracellular sensing in prokaryotes.

  4. Cache Domains That are Homologous to, but Different from PAS Domains Comprise the Largest Superfamily of Extracellular Sensors in Prokaryotes

    PubMed Central

    Upadhyay, Amit A.; Fleetwood, Aaron D.; Adebali, Ogun; Finn, Robert D.; Zhulin, Igor B.

    2016-01-01

    Cellular receptors usually contain a designated sensory domain that recognizes the signal. Per/Arnt/Sim (PAS) domains are ubiquitous sensors in thousands of species ranging from bacteria to humans. Although PAS domains were described as intracellular sensors, recent structural studies revealed PAS-like domains in extracytoplasmic regions in several transmembrane receptors. However, these structurally defined extracellular PAS-like domains do not match sequence-derived PAS domain models, and thus their distribution across the genomic landscape remains largely unknown. Here we show that structurally defined extracellular PAS-like domains belong to the Cache superfamily, which is homologous to, but distinct from the PAS superfamily. Our newly built computational models enabled identification of Cache domains in tens of thousands of signal transduction proteins including those from important pathogens and model organisms. Furthermore, we show that Cache domains comprise the dominant mode of extracellular sensing in prokaryotes. PMID:27049771

  5. 47 CFR 52.35 - Porting Intervals.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Portability § 52.35 Porting Intervals. (a) All telecommunications carriers required by the Commission to port telephone numbers must complete a simple wireline-to-wireline or simple intermodal port request within one... p.m. local time for a simple port request to be eligible for activation at midnight on the same...

  6. 47 CFR 52.35 - Porting Intervals.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Portability § 52.35 Porting Intervals. (a) All telecommunications carriers required by the Commission to port telephone numbers must complete a simple wireline-to-wireline or simple intermodal port request within one... p.m. local time for a simple port request to be eligible for activation at midnight on the same...

  7. 47 CFR 52.35 - Porting Intervals.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Portability § 52.35 Porting Intervals. (a) All telecommunications carriers required by the Commission to port telephone numbers must complete a simple wireline-to-wireline or simple intermodal port request within one... p.m. local time for a simple port request to be eligible for activation at midnight on the same...

  8. 47 CFR 52.35 - Porting Intervals.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Portability § 52.35 Porting Intervals. (a) All telecommunications carriers required by the Commission to port telephone numbers must complete a simple wireline-to-wireline or simple intermodal port request within one... p.m. local time for a simple port request to be eligible for activation at midnight on the same...

  9. 47 CFR 52.35 - Porting Intervals.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Portability § 52.35 Porting Intervals. (a) All telecommunications carriers required by the Commission to port telephone numbers must complete a simple wireline-to-wireline or simple intermodal port request within one... p.m. local time for a simple port request to be eligible for activation at midnight on the same...

  10. Hepatic Arterial Infusion Chemotherapy through a Port-Catheter System as Preoperative Initial Therapy in Patients with Advanced Liver Dysfunction due to Synchronous and Unresectable Liver Metastases from Colorectal Cancer

    SciTech Connect

    Iguchi, Toshihiro; Arai, Yasuaki; Inaba, Yoshitaka Yamaura, Hidekazu; Sato, Yozo; Miyazaki, Masaya; Shimamoto, Hiroshi

    2008-01-15

    Purpose. We retrospectively evaluated the safety and efficacy of preoperative initial hepatic arterial infusion chemotherapy (HAIC) through a port-catheter system in patients with liver dysfunction due to synchronous and unresectable liver metastases. The aim of HAIC was to improve patients' clinical condition for later surgical removal of primary colorectal cancer. Methods. Port-catheter systems were placed radiologically in 21 patients (mean age 58.6 {+-} 8.1 years) with liver dysfunction due to synchronous liver metastases from colorectal cancer. Initial HAIC of 1,000 mg/m{sup 2} 5-fluorouracil was administered weekly as a 5 hr continuous infusion through this system. Surgical removal of the primary lesion was planned after HAIC improved the liver function. Results. Port-catheter system placement was successful in all patients without severe complications. Patients were followed up for a median of 309 days (range 51-998 days). After starting HAIC, no severe adverse events that caused drug loss and treatment postponement or suspension were observed in any of the patients. HAIC was performed a mean of 4.5 {+-} 3.0 times and the liver function improved in all patients. Curative (n = 18) or palliative (n = 1) surgical removal of the primary lesion was performed. The remaining 2 patients died because extrahepatic metastases developed and their performance status worsened; thus, surgery could not be performed. The median survival times of all patients and the operated patients were 309 and 386 days, respectively. Conclusion. Initial HAIC administration is a safe and efficacious method for improving liver function prior to operative resection of primary colorectal cancer in patients with liver dysfunction due to synchronous and unresectable liver metastases.

  11. Beyond a series of security nets: Applying STAMP & STPA to port security

    SciTech Connect

    Williams, Adam D.

    2015-11-17

    Port security is an increasing concern considering the significant role of ports in global commerce and today’s increasingly complex threat environment. Current approaches to port security mirror traditional models of accident causality -- ‘a series of security nets’ based on component reliability and probabilistic assumptions. Traditional port security frameworks result in isolated and inconsistent improvement strategies. Recent work in engineered safety combines the ideas of hierarchy, emergence, control and communication into a new paradigm for understanding port security as an emergent complex system property. The ‘System-Theoretic Accident Model and Process (STAMP)’ is a new model of causality based on systems and control theory. The associated analysis process -- System Theoretic Process Analysis (STPA) -- identifies specific technical or procedural security requirements designed to work in coordination with (and be traceable to) overall port objectives. This process yields port security design specifications that can mitigate (if not eliminate) port security vulnerabilities related to an emphasis on component reliability, lack of coordination between port security stakeholders or economic pressures endemic in the maritime industry. As a result, this article aims to demonstrate how STAMP’s broader view of causality and complexity can better address the dynamic and interactive behaviors of social, organizational and technical components of port security.

  12. Evaluating the PAS-SIM model using a passive air sampler calibration study for pesticides.

    PubMed

    Restrepo, Andrés Ramírez; Hayward, Stephen J; Armitage, James M; Wania, Frank

    2015-07-01

    The main objective of this study was to evaluate the performance of a model for simulating the uptake of various pesticides on passive air samplers (PAS). From 2006-2007 a series of PAS using XAD-resin were deployed at Egbert, a rural agricultural site in southern Ontario, Canada, to measure the uptake of pesticides for time periods ranging from two months to one year. A continuous increase in sequestered amounts was observed for most pesticides, except for trifluralin and pendimethalin, which could conceivably be subject to substantial degradation inside the sampler. Continuous low-volume active air samples taken during the same period, along with data on weather conditions, allowed for the simulation of the uptake of the pesticides using the model (PAS-SIM). The modelled accumulation of pesticides on the PAS over the deployment period was in good agreement with the experimental data in most cases (i.e., within a factor of two) providing insight into the uptake kinetics of this type of sampler in the field. Passive sampling rates (PSR, m(3) d(-1)) were determined from the empirical data generated for this study using three different methods and compared with the PSRs generated by the model. Overall, the PAS-SIM model, which is capable of accounting for the influence of temperature and wind variations on PSRs, provided reasonable results that range between the three empirical approaches employed and well-established literature values. Further evaluation and application of the PAS-SIM model to explore the potential spatial and temporal variability in PAS uptake kinetics is warranted, particularly for established monitoring sites where detailed meteorological data are more likely to be available.

  13. 9 CFR 97.1 - Overtime work at laboratories, border ports, ocean ports, and airports. 1

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Overtime work at laboratories, border ports, ocean ports, and airports. 1 97.1 Section 97.1 Animals and Animal Products ANIMAL AND PLANT... laboratories, border ports, ocean ports, and airports. 1 1 For designated ports of entry for certain...

  14. 9 CFR 97.1 - Overtime work at laboratories, border ports, ocean ports, and airports. 1

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Overtime work at laboratories, border ports, ocean ports, and airports. 1 97.1 Section 97.1 Animals and Animal Products ANIMAL AND PLANT... laboratories, border ports, ocean ports, and airports. 1 1 For designated ports of entry for certain...

  15. 9 CFR 97.1 - Overtime work at laboratories, border ports, ocean ports, and airports. 1

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Overtime work at laboratories, border ports, ocean ports, and airports. 1 97.1 Section 97.1 Animals and Animal Products ANIMAL AND PLANT... laboratories, border ports, ocean ports, and airports. 1 1 For designated ports of entry for certain...

  16. 9 CFR 97.1 - Overtime work at laboratories, border ports, ocean ports, and airports. 1

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Overtime work at laboratories, border ports, ocean ports, and airports. 1 97.1 Section 97.1 Animals and Animal Products ANIMAL AND PLANT... laboratories, border ports, ocean ports, and airports. 1 1 For designated ports of entry for certain...

  17. Port Granby Project Overview - 13208

    SciTech Connect

    Smith, David W.; Vandergaast, Gary; Sungaila, Mark

    2013-07-01

    The Port Granby Project is an integral part of the Port Hope Area Initiative (PHAI), and is located approximately 14 kilometres west of the Municipality of Port Hope in the adjacent Municipality of Clarington, Ontario. The principal objective of the project is the excavation and relocation of low-level radioactive waste (LLRW) and marginally contaminated soils, which were deposited at the Port Granby Waste Management Facility (PGWMF) by Eldorado Nuclear Limited during the period 1955 to 1988, to a new, highly engineered above-ground Long-term Waste Management Facility (LTWMF) to be constructed on a nearby site. The Environmental Assessment for the Project was approved in 2009 August and the required Waste Nuclear Substance License was received in 2011 November. Once the detailed engineering design was completed, in 2011 March, the Port Granby Project was divided into three major contracts for construction implementation purposes. The first of these contracts was completed in late 2012 and the second is planned to start in early 2013. The contracting process for the third major contract is also expected to be completed during 2013. This paper provides an overview of the Port Granby Project as well as discussion on the status of the Project, including the regulatory approvals process, the approach to contracting the construction works and an update of work recently completed and soon to get underway. (authors)

  18. Shear-mediated platelet activation in patients implanted with continuous flow LVADs: A preliminary study utilizing the platelet activity state (PAS) assay.

    PubMed

    Valerio, Lorenzo; Consolo, Filippo; Bluestein, Danny; Tran, Phat; Slepian, Marvin; Redaelli, Alberto; Pappalardo, Federico

    2015-08-01

    Left ventricular assist devices (LVADs) have emerged as vital life-saving therapeutic systems for patients with advanced and end-stage heart failure (HF). Despite their efficacy, VAD systems remain limited by post-implantation thrombotic complications. Shear-mediated platelet activation is the major driver of such complications in these devices. Nowadays few platelet function assays are routinely utilized in assessing the degree of platelet activation in VAD implanted patients. No assays exist that specifically target shear-mediated platelet activation. The platelet activity state (PAS) is a novel assay that has been well validated in vitro, measuring thrombin release as a surrogate for shear-mediated platelet activation. To date limited data exist as to the utility of this assay in the clinical setting. In the present study we evaluated eight LVAD patients' platelet activation level using the PAS assay. Simultaneous measurements of conventional prothrombotic and hemolysis markers, - i.e. fibrinogen and lactate dehydrogenase (LDH) - were also performed. Trends as to alteration from baseline were studied. We observed that the PAS assay allowed detection of an abnormal level of platelet activation in one patient in our series who suffered from an overt thrombosis. Interestingly in the same patient no signal of major abnormality in fibrinogen or LDH was detected. Further for 7/8 patients who were free of thrombosis, no significant level of platelet activation was detected via PAS assay, while elevation in fibrinogen and LDH were observed. As such, from our observational series it appears that the PAS assay is a sensitive and specific indicator of shear-mediated platelet activation. Further patients' experience will help elucidate the role of this promising assay in the management of LVAD implanted patients.

  19. 3D visualization of port simulation.

    SciTech Connect

    Horsthemke, W. H.; Macal, C. M.; Nevins, M. R.

    1999-06-14

    Affordable and realistic three dimensional visualization technology can be applied to large scale constructive simulations such as the port simulation model, PORTSIM. These visualization tools enhance the experienced planner's ability to form mental models of how seaport operations will unfold when the simulation model is implemented and executed. They also offer unique opportunities to train new planners not only in the use of the simulation model but on the layout and design of seaports. Simulation visualization capabilities are enhanced by borrowing from work on interface design, camera control, and data presentation. Using selective fidelity, the designers of these visualization systems can reduce their time and efforts by concentrating on those features which yield the most value for their simulation. Offering the user various observational tools allows the freedom to simply watch or engage in the simulation without getting lost. Identifying the underlying infrastructure or cargo items with labels can provide useful information at the risk of some visual clutter. The PortVis visualization expands the PORTSIM user base which can benefit from the results provided by this capability, especially in strategic planning, mission rehearsal, and training. Strategic planners will immediately reap the benefits of seeing the impact of increased throughput visually without keeping track of statistical data. Mission rehearsal and training users will have an effective training tool to supplement their operational training exercises which are limited in number because of their high costs. Having another effective training modality in this visualization system allows more training to take place and more personnel to gain an understanding of seaport operations. This simulation and visualization training can be accomplished at lower cost than would be possible for the operational training exercises alone. The application of PORTSIM and PortVis will lead to more efficient

  20. The genetic basis for susceptibility to Rift Valley fever disease in MBT/Pas mice.

    PubMed

    Tokuda, S; Do Valle, T Z; Batista, L; Simon-Chazottes, D; Guillemot, L; Bouloy, M; Flamand, M; Montagutelli, X; Panthier, J-J

    2015-01-01

    The large variation in individual response to infection with Rift Valley fever virus (RVFV) suggests that host genetic determinants play a role in determining virus-induced disease outcomes. These genetic factors are still unknown. The systemic inoculation of mice with RVFV reproduces major pathological features of severe human disease, notably the hepatitis and encephalitis. A genome scan performed on 546 (BALB/c × MBT) F2 progeny identified three quantitative trait loci (QTLs), denoted Rvfs-1 to Rvfs-3, that were associated with disease susceptibility in MBT/Pas mice. Non-parametric interval-mapping revealed one significant and two suggestive linkages with survival time on chromosomes 2 (Rvfs-1), 5 (Rvfs-3) and 11 (Rvfs-2) with respective logarithm of odds (LOD) scores of 4.58, 2.95 and 2.99. The two-part model, combining survival time and survival/death, identified one significant linkage to Rvfs-2 and one suggestive linkage to Rvfs-1 with respective LOD scores of 5.12 and 4.55. Under a multiple model, with additive effects and sex as a covariate, the three QTLs explained 8.3% of the phenotypic variance. Sex had the strongest influence on susceptibility. The contribution of Rvfs-1, Rvfs-2 and Rvfs-3 to survival time of RVFV-infected mice was further confirmed in congenic mice.

  1. PAS domain containing chemoreceptor couples dynamic changes in metabolism with chemotaxis.

    PubMed

    Xie, Zhihong; Ulrich, Luke E; Zhulin, Igor B; Alexandre, Gladys

    2010-02-02

    Chemoreceptors provide sensory specificity and sensitivity that enable motile bacteria to seek optimal positions for growth and metabolism in gradients of various physicochemical cues. Despite the abundance of chemoreceptors, little is known regarding the sensory specificity and the exact contribution of individual chemoreceptors to the lifestyle of bacteria. Azospirillum brasilense are motile bacteria that can fix atmospheric nitrogen under microaerophilic conditions. Here, we characterized a chemoreceptor in this organism, named AerC, which functions as a redox sensor that enables the cells to seek microaerophilic conditions that support optimum nitrogen fixation. AerC is a representative of a widespread class of soluble chemoreceptors that monitor changes in the redox status of the electron transport system via the FAD cofactor associated with its PAS domains. In A. brasilense, AerC clusters at the cell poles. Its cellular localization and contribution to the behavioral response correlate with its expression pattern and with changes in the overall cellular FAD content under nitrogen-fixing conditions. AerC-mediated energy taxis in A. brasilense prevails under conditions of nitrogen fixation, illustrating a strategy by which cells optimize chemosensing to signaling cues that directly affect current metabolic activities and thus revealing a mechanism by which chemotaxis is coordinated with dynamic changes in cell physiology.

  2. Beyond a series of security nets: Applying STAMP & STPA to port security

    DOE PAGES

    Williams, Adam D.

    2015-11-17

    Port security is an increasing concern considering the significant role of ports in global commerce and today’s increasingly complex threat environment. Current approaches to port security mirror traditional models of accident causality -- ‘a series of security nets’ based on component reliability and probabilistic assumptions. Traditional port security frameworks result in isolated and inconsistent improvement strategies. Recent work in engineered safety combines the ideas of hierarchy, emergence, control and communication into a new paradigm for understanding port security as an emergent complex system property. The ‘System-Theoretic Accident Model and Process (STAMP)’ is a new model of causality based on systemsmore » and control theory. The associated analysis process -- System Theoretic Process Analysis (STPA) -- identifies specific technical or procedural security requirements designed to work in coordination with (and be traceable to) overall port objectives. This process yields port security design specifications that can mitigate (if not eliminate) port security vulnerabilities related to an emphasis on component reliability, lack of coordination between port security stakeholders or economic pressures endemic in the maritime industry. As a result, this article aims to demonstrate how STAMP’s broader view of causality and complexity can better address the dynamic and interactive behaviors of social, organizational and technical components of port security.« less

  3. Test Port for Fiber-Optic-Coupled Laser Altimeter

    NASA Technical Reports Server (NTRS)

    Ramos Izquierdo, Luis; Scott, V. Stanley; Rinis, Haris; Cavanaugh, John

    2011-01-01

    A test port designed as part of a fiber optic coupled laser altimeter receiver optical system allows for the back-illumination of the optical system for alignment verification, as well as illumination of the detector(s) for testing the receiver electronics and signal-processing algorithms. Measuring the optical alignment of a laser altimeter instrument is difficult after the instrument is fully assembled. The addition of a test port in the receiver aft-optics allows for the back-illumination of the receiver system such that its focal setting and boresight alignment can be easily verified. For a multiple-detector receiver system, the addition of the aft-optics test port offers the added advantage of being able to simultaneously test all the detectors with different signals that simulate the expected operational conditions. On a laser altimeter instrument (see figure), the aft-optics couple the light from the receiver telescope to the receiver detector(s). Incorporating a beam splitter in the aft-optics design allows for the addition of a test port to back-illuminate the receiver telescope and/or detectors. The aft-optics layout resembles a T with the detector on one leg, the receiver telescope input port on the second leg, and the test port on the third leg. The use of a custom beam splitter with 99-percent reflection, 1-percent transmission, and a mirrored roof can send the test port light to the receiver telescope leg as well as the detector leg, without unduly sacrificing the signal from the receiver telescope to the detector. The ability to test the receiver system alignment, as well as multiple detectors with different signals without the need to disassemble the instrument or connect and reconnect components, is a great advantage to the aft-optics test port. Another benefit is that the receiver telescope aperture is fully back-illuminated by the test port so the receiver telescope focal setting vs. pressure and or temperature can be accurately measured (as

  4. The Status of USITER Diagnostic Port Plug Neutronics Analysis Using Attila

    SciTech Connect

    Feder, Russell; Youssef, Mahamoud; Klabacha, Jonathan

    2013-11-01

    USITER is one of seven partner domestic agencies (DA) contributing components to the ITER project. Four diagnostic port plug packages (two equatorial ports and two upper ports) will be engineered and fabricated by Princeton Plasma Physics Lab (PPPL). Diagnostic port plugs as illustrated in Fig. 1 are large primarily stainless steel structures that serve several roles on ITER. The port plugs are the primary vacuum seal and tritium confinement barriers for the vessel. The port plugs also house several plasma diagnostic systems and other machine service equipment. Finally, each port plug must shield high energy neutrons and gamma photons from escaping and creating radiological problems in maintenance areas behind the port plugs. The optimization of the balance between adequate shielding and the need for high performance, high throughput diagnostics systems is the focus of this paper. Neutronics calculations are also needed for assessing nuclear heating and nuclear damage in the port plug and diagnostic components. Attila, the commercially available discrete-ordinates software package, is used for all diagnostic port plug neutronics analysis studies at PPPL.

  5. Evaluation of Intrahepatic Perfusion on Fusion Imaging Using a Combined CT/SPECT System: Influence of Anatomic Variations on Hemodynamic Modification Before Installation of Implantable Port Systems for Hepatic Arterial Infusion Chemotherapy

    SciTech Connect

    Ikeda, Osamu Tamura, Yoshitaka; Nakasone, Yutaka; Shiraishi, Shinya; Kawanaka, Kouichi; Tomiguchi, Seiji; Takamori, Hiroshi; Chikamoto, Akira; Kanemitsu, Keiichirou; Yamashita, Yasuyuki

    2007-06-15

    Background. In some patients with hepatic tumors, anatomic variations in the hepatic arteries may require hemodynamic modification to render effective hepatic arterial infusion chemotherapy delivered via implantable port systems. We used a combined CT/SPECT system to obtain fused images of the intrahepatic perfusion patterns in patients with such anatomic variations and assessed their effects on the treatment response of hepatic tumors. Methods. Using a combined SPECT/CT system, we obtained fused images in 110 patients with malignant liver tumors (n = 75) or liver metastasis from unresectable pancreatic cancer (n = 35). Patients with anatomic hepatic arteries variations underwent hemodynamic modification before the placement of implantable port systems for hepatic arterial infusion chemotherapy. We evaluated their intrahepatic perfusion patterns and the initial treatment response of their liver tumors. The perfusion patterns on the fused images were classified as homogeneous, local hypoperfusion, and/or perfusion defect. Using the WHO criteria of complete response (CR), partial response (PR), no change (NC), and progressive disease (PD), we evaluated the patients' tumor responses after 3 months on multislice helical CT scans. The treatment was regarded as effective in patients who achieved a complete response or partial response. Results. Anatomic hepatic artery variations were present in 15 of the 110 patients (13.6%); 5 manifested replacement of the left hepatic artery (LHA), 8 of the right hepatic artery (RHA), and 1 each had replacement of the RHA and LHA, and replacement of the LHA plus an accessory RHA. In 13 of these 15 patients (87%), occlusion with metallic coils was successful. On fusion imaging, the perfusion patterns were recorded as homogeneous in 6 patients (43%), as hypoperfusion in 7 (50%), and 1 patient had a perfusion defect (7.1%) in the embolized arterial region. Of the 8 patients with RHA replacement, 4 manifested a homogeneous distribution and

  6. Port Risk Assessment Port of Ponce, Guayanilla, Yabucoa, and Las Mareas, Puerto Rico, After Action Report

    DTIC Science & Technology

    2000-02-10

    Port Assessment Ponce, Guayanilla, Yabucoa, and Las Mareas Port of Ponce, Guayanilla, Yabucoa, and Las Mareas , Puerto Rico, After Action Report...Introduction. A Port Risk Assessment was conducted for the port of Ponce, Guayanilla, Yabucoa, and Las Mareas , Puerto Rico (South Central...3. DATES COVERED 00-00-2000 to 00-00-2000 4. TITLE AND SUBTITLE Port Risk Assessment Port of Ponce, Guayanilla, Yabucoa, and Las Mareas

  7. Pituitary Adenoma With Paraganglioma/Pheochromocytoma (3PAs) and Succinate Dehydrogenase Defects in Humans and Mice

    PubMed Central

    Xekouki, Paraskevi; Szarek, Eva; Bullova, Petra; Giubellino, Alessio; Quezado, Martha; Mastroyannis, Spyridon A.; Mastorakos, Panagiotis; Wassif, Christopher A.; Raygada, Margarita; Rentia, Nadia; Dye, Louis; Cougnoux, Antony; Koziol, Deloris; Sierra, Maria de La Luz; Lyssikatos, Charalampos; Belyavskaya, Elena; Malchoff, Carl; Moline, Jessica; Eng, Charis; Maher, Louis James; Pacak, Karel; Lodish, Maya

    2015-01-01

    Context: Germline mutations in genes coding succinate dehydrogenase (SDH) subunits A, B, C, and D have been identified in familial paragangliomas (PGLs)/pheochromocytomas (PHEOs) and other tumors. We described a GH-secreting pituitary adenoma (PA) caused by SDHD mutation in a patient with familial PGLs. Additional patients with PAs and SDHx defects have since been reported. Design: We studied 168 patients with unselected sporadic PA and with the association of PAs, PGLs, and/or pheochromocytomas, a condition we named the 3P association (3PAs) for SDHx germline mutations. We also studied the pituitary gland and hormonal profile of Sdhb+/− mice and their wild-type littermates at different ages. Results: No SDHx mutations were detected among sporadic PA, whereas three of four familial cases were positive for a mutation (75%). Most of the SDHx-deficient PAs were either prolactinomas or somatotropinomas. Pituitaries of Sdhb+/− mice older than 12 months had an increased number mainly of prolactin-secreting cells and several ultrastructural abnormalities such as intranuclear inclusions, altered chromatin nuclear pattern, and abnormal mitochondria. Igf-1 levels of mutant mice tended to be higher across age groups, whereas Prl and Gh levels varied according to age and sex. Conclusion: The present study confirms the existence of a new association that we termed 3PAs. It is due mostly to germline SDHx defects, although sporadic cases of 3PAs without SDHx defects also exist. Using Sdhb+/− mice, we provide evidence that pituitary hyperplasia in SDHx-deficient cells may be the initial abnormality in the cascade of events leading to PA formation. PMID:25695889

  8. Suit Port Aft Bulkhead Mockup 2008 Test Results

    NASA Technical Reports Server (NTRS)

    Romig, Barbara A.; Allton, Charles S.; Litaker, Harry L.

    2009-01-01

    The Lunar Electric Rover (LER), formerly called the Small Pressurized Rover (SPR), is currently being carried as an integral part of the current Lunar Surface Architectures under consideration in the Constellation program. One element of the LER is the suit port, the means by which the crew performs Extravehicular Activities (EVAs). Two suit port deliverables were produced in fiscal year 2008: an aft bulkhead mockup for functional integrated testing with the 1-G LER mockup and a functional and pressurizable Engineering Unit (EU). This paper focuses on the aft bulkhead mockup test results from Desert Research and Technology Studies (D-RATS) October 2008 testing at Black Point Lava Flow (BPLF), Arizona. Refer to 39th International Conference on Environmental Systems (ICES) for test results of the EU. The suit port aft bulkhead mockup was integrated with the mockup of the LER cabin and chassis. It is located on the aft bulkhead of the LER cabin structure and includes hatches, a locking mechanism, seals, interior and exterior suit don/doff aids, and exterior platforms to accommodate different crewmember heights. A lightweight mockup of the Mark III suit was tested with the suit port aft bulkhead mockup. There are several limitations to the suit port and mockup suits, and results of the suit port evaluation are presented and interpreted within the context of the limitations.

  9. PIV Application to Fluid Dynamics of Bass Reflex Ports

    NASA Astrophysics Data System (ADS)

    Rossi, Massimiliano; Esposito, Enrico; Tomasini, Enrico Primo

    A bass reflex (or vented or ported) loudspeaker system (BRS) is a particular type of loudspeaker enclosure that makes use of the combination of two second-order mechanic/acoustic devices, i.e., the driver and a Helmotz resonator, in order to create a new system with reinforced emission in the low frequency region. The resonator is composed by the box itself in which one or more ports are present with suitable shapes and dimensions. This category of loudspeaker presents several advantages compared to closed-box systems such as higher efficiency and power, smaller dimensions and reduced distortion at lower frequencies. Notwithstanding these advantages, they present some drawbacks like more complexity and unloading of the cone below the tuning frequency. Moreover, at high power levels the airflow in the port(s) may generate unwanted noises due to turbulence as well as distortion and acoustic compression. In this work we will present and compare a series of experiments conducted on two different bass reflex ports designs to assess their performance in terms of flow turbulence and sound-level compression at high input power levels. These issues are quite important in professional sound systems, where increasing power levels and sound clarity require exponentially growing cost and weight. For these reasons it is vital to optimize port design. To the knowledge of the authors there does not exist an accurate, nonintrusive experimental full-field study of air flows emitting from reflex ports in operating conditions. In this work, the experimental fluid dynamic investigation has been conducted by means of PIV and LDA techniques.

  10. Periodic acid-Schiff (PAS) staining of immature platelets in donors.

    PubMed

    Pogorelov, Valery M; Beskorovainova, Victoria Ju; Chanieva, Marem I; Dyagileva, Olga A; Naumova, Iren N; Skedina, Marina A

    2012-01-01

    Glycogen in platelets (PLTs) on smears of peripheral blood of 40 donors was investigated by the periodic acid-Schiff (PAS) method. Three groups were formed. Group 1 was consisted of 21 men undergoing the donor selection procedure. Additionally, 9 first-time donors undergoing plateletpheresis (Group 2) and 10 donors who frequently underwent platelet apheresis (Group 3) were studied as a model of relative thrombocytopenia. Cell sizes were measured with the use of a Image Analyzer "ASPBC" (Russia). The training procedure and classification of PAS-blood PLTs were made on the basis of expert evaluation. In this article, we have established three facts. First, the PAS-positive PLT area was larger than that of the PAS-negative cells (9.5 ± 3.6 sq.mkm vs. 3.9 ± 1.3 sq.mkm, p < 0.001, n = 21). The PAS-positivity of PLTs was 23.1 ± 9.2%. Second, the PAS-positivity correlated (r(S) = 0.63, p < 0.05) with the immature platelets fraction (IPF %), determined using Sysmex XE-2100. The mean IPF was 2.1 ± 1.0% (range 0.3-4.6%). Third, using the IPF% values obtained in Group 1, we found a significantly higher level of IPF in the samples both in Group 2 [mean value 4.2 ± 2.0% (range 1.9-7.0), p < 0.01] and in Group 3 [mean value 5.1 ± 2.5% (range 1.2-8.6), p < 0.004] with relative thrombocytopenia [Group 2: median 198 (95% confidence interval, CI 166-227) vs. median 229 (95% CI 206-267), p < 0.05; Group 3: median 142.5 (95% CI 132-173) vs. median 214.5 (95% CI 196-267), p < 0.01] after plateletpheresis. There was also a significant difference between the pre- and post-plateletpheresis for IPF% in Group 2 and Group 3: median 1.7 (95% CI 1.4-4.0) vs. median 4.0 (95% CI 2.7-5.8), p < 0.05 and median 4.0 (95% CI 2.7-6.0) vs. median 5.1 (95% CI 3.3-6.9), p < 0.01. The increased IPF shows a correlation with the PAS positivity [r(S) = 0.5 (p = 0.14) and r(S) = 0.6 (p = 0.05)] which has a tendency to

  11. Interface Circuit For Printer Port

    NASA Technical Reports Server (NTRS)

    Tucker, Jerry H.; Yadlowsky, Ann B.

    1991-01-01

    Electronic circuit, called printer-port interface circuit (PPI) developed to overcome certain disadvantages of previous methods for connecting IBM PC or PC-compatible computer to other equipment. Has both reading and writing modes of operation. Very simple, requiring only six integrated circuits. Provides for moderately fast rates of transfer of data and uses existing unmodified circuit card in IBM PC. When used with appropriate software, circuit converts printer port on IBM PC, XT, AT, or compatible personal computer to general purpose, 8-bit-data, 16-bit address bus that connects to multitude of devices.

  12. The VisPort Project: Visualization of Port Logistics

    ERIC Educational Resources Information Center

    Katsioloudis, Petros J.; Watson, Ginger

    2011-01-01

    There is concern about the diminishing availability of skilled personnel that can operate in the wide variety of disciplines associated with port operations. Increasing cargo volume, combined with a shrinking workforce, could potentially create alarming situations in the future, hence the motivation to publicize to current students the breadth and…

  13. Crystal structure of the PAS domain of the hEAG potassium channel.

    PubMed

    Tang, Xue; Shao, Juan; Qin, Xiaohong

    2016-08-01

    KCNH voltage-gated potassium channels play critical roles in regulating cellular functions. The channel is composed of four subunits, each of which contains six transmembrane helices forming the central pore. The cytoplasmic parts of the subunits present a Per-Arnt-Sim (PAS) domain at the N-terminus and a cyclic nucleotide-binding homology domain at the C-terminus. PAS domains are conserved from prokaryotes to eukaryotes and are involved in sensing signals and cellular responses. To better understand the functional roles of PAS domains in KCNH channels, the structure of this domain from the human ether-à-go-go channel (hEAG channel) was determined. By comparing it with the structures of the Homo sapiens EAG-related gene (hERG) channel and the Drosophila EAG-like K(+) (dELK) channel and analyzing the structural features of the hEAG channel, it was identified that a hydrophobic patch on the β-sheet may mediate interaction between the PAS domain and other regions of the channel to regulate its functions.

  14. Calibration and application of a passive air sampler (XAD-PAS) for volatile methyl siloxanes.

    PubMed

    Krogseth, Ingjerd S; Zhang, Xianming; Lei, Ying D; Wania, Frank; Breivik, Knut

    2013-05-07

    Because the atmosphere is key to understanding the environmental behavior of volatile methyl siloxanes (VMS), a variety of reliable air sampling methods are needed. The purpose of this study was to calibrate and evaluate an existing, polystyrene-divinylbenzene copolymeric resin-based passive air sampler (XAD-PAS) for VMS. Sixteen XAD-PAS were deployed for 7-98 days at a suburban site in Toronto, Canada, while the VMS concentration in air was monitored by an active sampling method. This calibration and a subsequent field test further allowed for investigation of the temporal and spatial variability of VMS in the region. Uptake in the XAD-PAS of octamethylcyclotetrasiloxane (D4), decamethylcyclopentasiloxane (D5), and three linear VMS was linear throughout the whole deployment period. Sampling rates were between 0.4 and 0.5 m(3)/day. The XAD-PAS measured ∑VMS concentrations ranged from nondetects in rural areas (n = 3), to 169 ± 49 ng/m(3) in the urban region (n = 21), to levels above 600 ng/m(3) at sewage treatment plants (n = 2). Levels and composition of VMS within the urban area were remarkably uniform in space. Levels, but not composition, were highly variable in time and weakly correlated with temperature, wind speed, and wind direction.

  15. Searching for planetary nebulae at the Galactic halo via J-PAS

    NASA Astrophysics Data System (ADS)

    Gonçalves, Denise R.; Aparício-Villegas, T.; Akras, S.; Cortesi, A.; Borges-Fernandes, M.; Daflon, S.; Pereira, C. B.; Lorenz-Martins, S.; Marcolino, W.; Kanaan, A.; Viironen, K.; de Oliveira, C. Mendes; Molino, A.; Ederoclite, A.

    2016-08-01

    The Javalambre-Physics of the Accelerating Universe Astrophysical Survey (J-PAS) is a narrow-band imaging, very wide field cosmological survey. It will last 5 years and will observe 8500 sq. deg. of the sky. There will be 54 contiguous narrow-band filters of 145Å FWHM, from 3,500 to 10,000Å. Two broad-band filters will be added at the extremes, UV and IR, plus the 3-g, r, and i- SDSS filters. Thus, J-PAS can be an important tool to search for new planetary nebulae (PNe) at the halo, increasing their numbers, because only 14 of them have been convincingly identified in the literature. Halo PNe are able to reveal precious information for the study of stellar evolution and the early chemical conditions of the Galaxy. The characteristic low continuum and intense emission lines of PNe make them good objects to be searched by J-PAS. Though covering a significantly smaller sky area, data from the ALHAMBRA survey were used to test our J-PAS strategy to search for PNe. Our first results are shown in this contribution.

  16. Effects of the bHLH domain on axial coordination of heme in the PAS-A domain of neuronal PAS domain protein 2 (NPAS2): conversion from His119/Cys170 coordination to His119/His171 coordination.

    PubMed

    Uchida, Takeshi; Sagami, Ikuko; Shimizu, Toru; Ishimori, Koichiro; Kitagawa, Teizo

    2012-03-01

    Neuronal PAS domain protein 2 (NPAS2), which is a CO-dependent transcription factor, consists of a basic helix-loop-helix domain (bHLH), and two heme-containing PAS domains (PAS-A and PAS-B). In our previous study on the isolated PAS-A domain, we concluded that His119 and Cys170 are the axial ligands of the ferric heme, while Cys170 is replaced by His171 upon reduction of heme (Uchida et al., J. Biol. Chem. 270, (2005) 21358-21368.). Recently, we characterized the PAS-A domain combined with the N-terminal bHLH domain, and found that some spectroscopic features were different from those of the isolated PAS-A domain (Mukaiyama et al., FEBS J. 273, (2006) 2528-2539.). Therefore, we reinvestigated the coordination structure of heme in the bHLH-PAS-A domain and prepared four histidine and one cysteine mutants. Resonance Raman spectrum of the Cys170Ala mutant is the same as that of wild type with a dominant 6-coordinate heme in the ferric form. In contrast, His119Ala and His171Ala mutants significantly increase amounts of the 5-coordinate species, indicating that His119 and His171, not Cys170, are axial ligands of the ferric heme in the bHLH-PAS-A domain. We had confirmed that the coordination structure of the isolated PAS-A domain is in equilibrium between Cys-Fe-His and His-Fe-His coordinated species but newly found that interaction of the PAS-A domain with the bHLH domain shifts the equilibrium toward the latter structure. Such flexibility in the heme coordination structure seems to be in favor of signal transduction in NPAS2.

  17. Ports Primer: 7.1 Environmental Impacts

    EPA Pesticide Factsheets

    Port operations can lead to environmental impacts on air, water and land. Many communities with environmental justice concerns also experience disparities in health outcomes that they attribute to exposure to emissions from port operations.

  18. Draft Environmental Justice Primer for Ports

    EPA Pesticide Factsheets

    This document is intended to help port decision-makers better understand the needs of near-port communities and how they can help address these needs and build productive community relationships during planning activities and operations.

  19. Supplement Analysis for the Transmission System Vegetation Management Program FEIS (DOE/EIS-0285/SA-28) - Port Angeles - Sappo No.1 Transmission Line ROW

    SciTech Connect

    Martin, Mark A.

    2001-09-05

    Vegetation Management along the Port Angeles - Sappo No.1 Transmission Line ROW, from structure 1/1 to structure 42/10. BPA proposes to clear unwanted vegetation in the rights-of-ways and around tower structures that may impede the operation and maintenance of the subject transmission line. BPA plans to conduct vegetation control with the goal of removing tall growing vegetation that is currently or will soon be a hazard to the transmission line. BPA’s overall goal is to have low-growing plant communities along the rights-of-way to control the development of potentially threatening vegetation. All work will be executed in accordance with the National Electrical Safety Code and BPA standards.

  20. 46 CFR 171.116 - Port lights.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Port lights. 171.116 Section 171.116 Shipping COAST... Port lights. (a) A vessel may have port lights below the bulkhead deck if— (1) It is greater than 150 gross tons; and (2) It is in ocean service. (b) All port lights in a space must be non-opening if...

  1. 46 CFR 171.116 - Port lights.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Port lights. 171.116 Section 171.116 Shipping COAST... Port lights. (a) A vessel may have port lights below the bulkhead deck if— (1) It is greater than 150 gross tons; and (2) It is in ocean service. (b) All port lights in a space must be non-opening if...

  2. Gulf Coast. Ports for Naval Defense

    DTIC Science & Technology

    1993-09-01

    information on these facilities. FUTURE DEVELOPMENT The Port Authority of the Port of Port Arthur recently purchased 33 acres of cleared waterfront land...Commander S1I79th Army Deployment Control Unit Fort Hamilton USARC Brooklyn , NY 11252-7445 (1) Commander 1182d Transportation Terminal Unit USAR...2011A 200 Stovall Street Alexandria, VA 22332-2300 (1) Commanding Officer Navy Cargo Handling and Port Group Williamsburg , VA 23185 (1) Commanding

  3. Cruise Ship Port Planning Factors

    DTIC Science & Technology

    2001-01-01

    The cruise ship industry started off like a healthy plant in a small pot. When it was small, it struggled, survived and flourished in the small pot... cruise ship port planning issues, and demonstrates that the market demand will continue to increase in the future. This increase in demand will be driven

  4. Multi-port dump combustor

    SciTech Connect

    Dale, L. A.; Grenleski Jr., S. E.; Keirsey, J. L.; Stevens, C. E.

    1985-09-10

    A four-ported dump combustor is designed for use with a ramjet engine and provides high combustion efficiency and pressure recovery for length-to-diameter (L/D) ratios of between 1.3 and 4.4, over a range of operating conditions.

  5. Compressor ported shroud for foil bearing cooling

    DOEpatents

    Elpern, David G.; McCabe, Niall; Gee, Mark

    2011-08-02

    A compressor ported shroud takes compressed air from the shroud of the compressor before it is completely compressed and delivers it to foil bearings. The compressed air has a lower pressure and temperature than compressed outlet air. The lower temperature of the air means that less air needs to be bled off from the compressor to cool the foil bearings. This increases the overall system efficiency due to the reduced mass flow requirements of the lower temperature air. By taking the air at a lower pressure, less work is lost compressing the bearing cooling air.

  6. Single-port plus an additional port robotic complete mesocolic excision and intracorporeal anastomosis using a robotic stapler for right-sided colon cancer

    PubMed Central

    Bae, Sung Uk; Jeong, Woon Kyung

    2016-01-01

    The concept of complete mesocolic excision and central vascular ligation for colonic cancer has been recently introduced. The paper describes a technique of right-sided complete mesocolic excision and intracorporeal anastomosis by using a single-port robotic approach with an additional conventional robotic port. We performed a single-port plus an additional port robotic surgery using the Da Vinci Single-Site platform via the Pfannenstiel incision and the wristed robotic instruments via an additional robotic port in the left lower quadrant. The total operative and docking times were 280 and 25 minutes, respectively. The total number of lymph nodes harvested was 36 and the proximal and distal resection margins were 31 and 50 cm, respectively. Single-port plus an additional port robotic surgery for right-sided complete mesocolic excision and intracorporeal anastomosis appears to be feasible and safe. This system can overcome certain limitations of the previous robotic systems and conventional single-port laparoscopic surgery. PMID:27757400

  7. 50 CFR 24.12 - Designated ports.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) The U.S. Department of Agriculture ports at Hilo, Hawaii, and Chicago, Illinois, are designated ports... CFR part 17 or 23. (c) The U.S. Department of Agriculture ports at Atlanta, Georgia; Chicago, Illinois... Chicago, Illinois Baton Rouge, Louisiana New Orleans, Louisiana Bangor, Maine Portland, Maine...

  8. 22 CFR 120.24 - Port Directors.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Port Directors. 120.24 Section 120.24 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS PURPOSE AND DEFINITIONS § 120.24 Port Directors. Port Directors of U.S. Customs and Border Protection means the U.S. Customs and...

  9. 22 CFR 120.24 - Port Directors.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Port Directors. 120.24 Section 120.24 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS PURPOSE AND DEFINITIONS § 120.24 Port Directors. Port Directors of U.S. Customs and Border Protection means the U.S. Customs and...

  10. 22 CFR 120.24 - Port Directors.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Port Directors. 120.24 Section 120.24 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS PURPOSE AND DEFINITIONS § 120.24 Port Directors. Port Directors of U.S. Customs and Border Protection means the U.S. Customs and...

  11. 22 CFR 120.24 - Port Directors.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Port Directors. 120.24 Section 120.24 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS PURPOSE AND DEFINITIONS § 120.24 Port Directors. Port Directors of U.S. Customs and Border Protection means the U.S. Customs and...

  12. 22 CFR 120.24 - Port Directors.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Port Directors. 120.24 Section 120.24 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS PURPOSE AND DEFINITIONS § 120.24 Port Directors. Port Directors of U.S. Customs and Border Protection means the U.S. Customs and...

  13. Single port laparoscopic mesh rectopexy

    PubMed Central

    2016-01-01

    Introduction Traditionally, laparoscopic mesh rectopexy is performed with four ports, in an attempt to improve cosmetic results. Following laparoscopic mesh rectopexy there is a new operative technique called single-port laparoscopic mesh rectopexy. Aim To evaluate the single-port laparoscopic mesh rectopexy technique in control of rectal prolapse and the cosmesis and body image issues of this technique. Material and methods The study was conducted in El Fayoum University Hospital between July 2013 and November 2014 in elective surgery for symptomatic rectal prolapse with single-port laparoscopic mesh rectopexy on 10 patients. Results The study included 10 patients: 3 (30%) males and 7 (70%) females. Their ages ranged between 19 years and 60 years (mean: 40.3 ±6 years), and they all underwent laparoscopic mesh rectopexy. There were no conversions to open technique, nor injuries to the rectum or bowel, and there were no mortalities. Mean operative time was 120 min (range: 90–150 min), and mean hospital stay was 2 days (range: 1–3 days). Preoperatively, incontinence was seen in 5 (50%) patients and constipation in 4 (40%). Postoperatively, improvement in these symptoms was seen in 3 (60%) patients for incontinence and in 3 (75%) for constipation. Follow-up was done for 6 months and no recurrence was found with better cosmetic appearance for all patients. Conclusions Single-port laparoscopic mesh rectopexy is a safe procedure with good results as regards operative time, improvement in bowel function, morbidity, cost, and recurrence, and with better cosmetic appearance. PMID:27350840

  14. Coal fueled ported kiln direct reduction process in Norway

    SciTech Connect

    Rierson, D.W.

    1994-12-31

    Allis Mineral Systems (AMS), formerly the minerals processing group at Allis-Chalmers Corporation, developed a ported kiln process in the 1960`s specifically for the direct reduction of iron ore. The process is called ACCAR. This ported kiln technology has more recently been coupled with AMS` GRATE-KILN System for iron oxide pelletizing into the GRATE-CAR Process, for minerals reduction. The GRATE-CAR Process can handle a fine grained ore concentrate through the steps of agglomeration, induration and reduction in a single production line.

  15. General view looking aft along the port side of the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view looking aft along the port side of the Orbiter Discovery into its payload bay. Note the Remote Manipulator System, Canadarm, in the foreground mounted on the port side longeron. The Remote Sensor Arm is mounted on the opposite, starboard, longeron. Also note the airlock and the protective covering over the docking mechanism. This image was taken in the Orbiter Processing Facility at Kennedy Space Center. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  16. The port side view of the Orbiter Discovery while mounted ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    The port side view of the Orbiter Discovery while mounted atop the 76-wheeled orbiter transfer system as it is being rolled from the Orbiter Processing Facility to the Vehicle Assembly Building at Kennedy Space Center. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  17. An oblique view of the forward fuselage and port side ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    An oblique view of the forward fuselage and port side of the Orbiter Discovery while mounted atop the 76-wheeled orbiter transfer system as it is being rolled from the Orbiter Processing Facility to the Vehicle Assembly Building at Kennedy Space Center. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  18. View of the forward section, port side, of the Orbiter ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of the forward section, port side, of the Orbiter Discovery at ground level in the Vehicle Assembly Building at NASA's Kennedy Space Center. Note the exposed panels for systems access during ground support and vehicle turn-around processes. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  19. HFB : A FASTBUS multi event double port buffer memory

    SciTech Connect

    Cerrito, L.; Lebbolo, H.

    1986-02-01

    The authors describe here the FB double port buffer memory developed at the LPNHE of the University Paris VI. Its purposes are to make available same features useful in the High Energy environment, to reduce, for a given amount of memory, the dead time data collection in a large size (in term of read-out channels) High Energy experiment and to get a buffer of memory as cheap and reliable as possible. The FB protocol, on the crate and cable side, is exploited using the coupler on 4 PAL's developed by G.Fremont and E.Sanchis. The DATA-Space is divided in 4 independent smaller blocks in a way such that a block can be accessed from a port while a different block is accessed from the other port. The two ports are: A, the FB crate port and B, the FB cable port. The buffer works as a rotary FIFO, looping over the 4 blocks of memory, but allowing for any random access. A mechanism is implemented on the board in order to be able to link different modules placed everywhere. If there are m modules, the looping will be around m 4 memory blocks. A multi event function is implemented on the board. HFB is quiped of two NTA for the DATA-Space on the port ''A'', and a flag to choose between them, to allow for a FB spying of DATA during the DAS dead time. HFB is a buffer of memory which can be used at each stage of a DAS: Frontend, Intermediate (MEB) or final, being completely FB standard. The HFB was designed for the LEP data acquisition system.

  20. An overview of San Francisco Bay PORTS

    USGS Publications Warehouse

    Cheng, Ralph T.; McKinnie, David; English, Chad; Smith, Richard E.

    1998-01-01

    The Physical Oceanographic Real-Time System (PORTS) provides observations of tides, tidal currents, and meteorological conditions in real-time. The San Francisco Bay PORTS (SFPORTS) is a decision support system to facilitate safe and efficient maritime commerce. In addition to real-time observations, SFPORTS includes a nowcast numerical model forming a San Francisco Bay marine nowcast system. SFPORTS data and nowcast numerical model results are made available to users through the World Wide Web (WWW). A brief overview of SFPORTS is presented, from the data flow originated at instrument sensors to final results delivered to end users on the WWW. A user-friendly interface for SFPORTS has been designed and implemented. Appropriate field data analysis, nowcast procedures, design and generation of graphics for WWW display of field data and nowcast results are presented and discussed. Furthermore, SFPORTS is designed to support hazardous materials spill prevention and response, and to serve as resources to scientists studying the health of San Francisco Bay ecosystem. The success (or failure) of the SFPORTS to serve the intended user community is determined by the effectiveness of the user interface.

  1. Does Faux Pas Detection in Adult Autism Reflect Differences in Social Cognition or Decision-Making Abilities?

    ERIC Educational Resources Information Center

    Thiébaut, Flora I.; White, Sarah J.; Walsh, Annabel; Klargaard, Solja K.; Wu, Hsuan-Chen; Rees, Geraint; Burgess, Paul W.

    2016-01-01

    43 typically-developed adults and 35 adults with ASD performed a cartoon faux pas test. Adults with ASD apparently over-detected faux pas despite good comprehension abilities, and were generally slower at responding. Signal detection analysis demonstrated that the ASD participants had significantly greater difficulty detecting whether a cartoon…

  2. Does Faux Pas Detection in Adult Autism Reflect Differences in Social Cognition or Decision-Making Abilities?

    PubMed

    Thiébaut, Flora I; White, Sarah J; Walsh, Annabel; Klargaard, Solja K; Wu, Hsuan-Chen; Rees, Geraint; Burgess, Paul W

    2016-01-01

    43 typically-developed adults and 35 adults with ASD performed a cartoon faux pas test. Adults with ASD apparently over-detected faux pas despite good comprehension abilities, and were generally slower at responding. Signal detection analysis demonstrated that the ASD participants had significantly greater difficulty detecting whether a cartoon depicted a faux pas and showed a liberal response bias. Test item analysis demonstrated that the ASD group were not in agreement with a reference control group (n = 69) about which non-faux pas items were most difficult. These results suggest that the participants with ASD had a primary problem with faux pas detection, but that there is another factor at work, possibly compensatory, that relates to their choice of a liberal response criterion.

  3. 76 FR 4417 - Liberty Natural Gas LLC, Liberty Liquefied Natural Gas (LNG) Deepwater Port License Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-25

    ... Maritime Administration Liberty Natural Gas LLC, Liberty Liquefied Natural Gas (LNG) Deepwater Port License.... Liberty Deepwater Port would receive and transfer natural gas from purpose-built LNG regasification... equipped to vaporize LNG cargo to natural gas through onboard closed loop vaporization systems and...

  4. 33 CFR 149.325 - What emergency communications equipment must be on a manned deepwater port?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... in the event the primary communications system outlined in § 149.140 fails. This communication... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false What emergency communications... communications equipment must be on a manned deepwater port? Each manned deepwater port must have a...

  5. Practical Analysis of materials with depth varying compositions using FT-IR photoacoustic spectroscopy (PAS)

    SciTech Connect

    J.F. McClelland; R.W. Jones; Siquan Luo

    2004-09-30

    FT-IR photoacoustic spectroscopy (PAS) is discussed as a nondestructive method to probe the molecular composition of materials versus depth on the basis of the analysis of layers of experimentally controllable thickness, which are measured from the sample surface to depths of some tens of micrometers, depending on optical and thermal properties. Computational methods are described to process photoacoustic amplitude and phase spectra for both semi-quantitative and quantitative depth analyses. These methods are demonstrated on layered and gradient samples.

  6. Porting LAMMPS to GPUs.

    SciTech Connect

    Brown, William Michael; Plimpton, Steven James; Wang, Peng; Agarwal, Pratul K.; Hampton, Scott; Crozier, Paul Stewart

    2010-03-01

    LAMMPS is a classical molecular dynamics code, and an acronym for Large-scale Atomic/Molecular Massively Parallel Simulator. LAMMPS has potentials for soft materials (biomolecules, polymers) and solid-state materials (metals, semiconductors) and coarse-grained or mesoscopic systems. It can be used to model atoms or, more generically, as a parallel particle simulator at the atomic, meso, or continuum scale. LAMMPS runs on single processors or in parallel using message-passing techniques and a spatial-decomposition of the simulation domain. The code is designed to be easy to modify or extend with new functionality.

  7. Applications of Multi Port Amplifier to personal satellite communications

    NASA Technical Reports Server (NTRS)

    Egami, Shunichiro

    1995-01-01

    In personal satellite communications, satellite antenna beam becomes narrow, and number of beams will be thirty to more than one hundred. This paper shows that Multi Port Amplifier is most suitable to multiple beam transmitter for personal communications satellite. It was shown that the single beam coverage area(cell) diameter is determined by personal earth station(PES) eirp, uplink C/No and uplink frequency band. Required number of cells for European or North American regional coverage at FPLMTS uplink frequency band is shown as around 32. It was shown that 32 beams systems will be easily implemented by using 2 set of 16-port MPA. Redundancy to SSPA failure is considered by increasing number of SSPAs. Actual configuration for 16-port MPA are briefly shown. The presented configuration will be easy to implement and the most economical solution.

  8. Principles of Ligand Binding within a Completely Buried Cavity in HIF2[alpha] PAS-B

    SciTech Connect

    Key, Jason; Scheuermann, Thomas H.; Anderson, Peter C.; Daggett, Valerie; Gardner, Kevin H.

    2010-04-19

    Hypoxia-inducible factors (HIFs) are heterodimeric transcription factors responsible for the metazoan hypoxia response and promote tumor growth, metastasis, and resistance to cancer treatment. The C-terminal Per-ARNT-Sim (PAS) domain of HIF2{alpha} (HIF2{alpha} PAS-B) contains a preformed solvent-inaccessible cavity that binds artificial ligands that allosterically perturb the formation of the HIF heterodimer. To better understand how small molecules bind within this domain, we examined the structures and equilibrium and transition-state thermodynamics of HIF2{alpha} PAS-B with several artificial ligands using isothermal titration calorimetry, NMR exchange spectroscopy, and X-ray crystallography. Rapid association rates reveal that ligand binding is not dependent upon a slow conformational change in the protein to permit ligand access, despite the closed conformation observed in the NMR and crystal structures. Compensating enthalpic and entropic contributions to the thermodynamic barrier for ligand binding suggest a binding-competent transition state characterized by increased structural disorder. Finally, molecular dynamics simulations reveal conversion between open and closed conformations of the protein and pathways of ligand entry into the binding pocket.

  9. Noninvasive glucose sensing in scattering media using OCT, PAS, and TOF techniques

    NASA Astrophysics Data System (ADS)

    Alarousu, Erkki; Hast, Jukka T.; Kinnunen, Matti T.; Kirillin, Mikhail Y.; Myllyla, Risto A.; Plucinski, Jerzy; Popov, Alexey P.; Priezzhev, Alexander V.; Prykari, Tuukka; Saarela, Juha; Zhao, Zuomin

    2004-08-01

    In this paper, optical measurement techniques, which enable non-invasive measurement, are superimposed to glucose sensing in scattering media. Used measurement techniques are Optical Coherence Tomography (OCT), Photoacoustic spectroscopy (PAS) and laser pulse Time-of-Flight (TOF) measurement using a streak camera. In parallel with measurements, a Monte-Carlo (MC) simulation models have been developed. Experimental in vitro measurements were performed using Intralipid fat emulsion as a tissue simulating phantom for OCT and TOF measurements. In PAS measurements, a pork meat was used as a subject but also preliminary in vivo measurements were done. OCT measurement results show that the slope of the OCT signal's envelope changes as a function of glucose content in the scattering media. TOF measurements show that the laser pulse full width of half maximum (FWHM) changes a little as function of glucose content. An agreement with MC-simulations and measurements with Intralipid was also found. Measurement results of PAS technique show that changes in glucose content in the pork meat tissue can be measured. In vivo measurements with a human volunteer show that other factors such as physiological change, blood circulation and body temperature drift may interfere the PA response of glucose.

  10. A cell cycle kinase with tandem sensory PAS domains integrates cell fate cues

    PubMed Central

    Mann, Thomas H.; Seth Childers, W.; Blair, Jimmy A.; Eckart, Michael R.; Shapiro, Lucy

    2016-01-01

    All cells must integrate sensory information to coordinate developmental events in space and time. The bacterium Caulobacter crescentus uses two-component phospho-signalling to regulate spatially distinct cell cycle events through the master regulator CtrA. Here, we report that CckA, the histidine kinase upstream of CtrA, employs a tandem-PAS domain sensor to integrate two distinct spatiotemporal signals. Using CckA reconstituted on liposomes, we show that one PAS domain modulates kinase activity in a CckA density-dependent manner, mimicking the stimulation of CckA kinase activity that occurs on its transition from diffuse to densely packed at the cell poles. The second PAS domain interacts with the asymmetrically partitioned second messenger cyclic-di-GMP, inhibiting kinase activity while stimulating phosphatase activity, consistent with the selective inactivation of CtrA in the incipient stalked cell compartment. The integration of these spatially and temporally regulated signalling events within a single signalling receptor enables robust orchestration of cell-type-specific gene regulation. PMID:27117914

  11. [Parental alienation syndrome (PAS): unknown in medical settings, endemic in courts].

    PubMed

    Pignotti, Maria Serenella

    2013-02-01

    A purposed syndrome of so-called parental alienation (PAS), unsupported by any evidence-based data, unknown in medical settings, unquoted in medical books, absent in DSM and ICD, never demonstrated by controlled studies published in high scientific level journals, is rampant in Courts where it can lead to loose parental custody. During a divorce trial, almost always the mothers and the children, become joint in a sort of folie au deux, in a denigration campaign of ex-husband/father. From a review on this issue it seems evident its theoretical roots lie on a theory that justify gender violence and children sexual abuse. The bias that both of them are layers and that he children have not autonomy block their possibility of any defence in front of a Court. In severe cases, PAS becomes a new and efficient tool of intra-familiar violence. The treatment of severe cases is to stop any contact between mother and children. The resort to PAS in Courts must be strongly rejected.

  12. Intraarterial Infusion Therapy via a Subcutaneous Port for Limb-Threatening Ischemia: A Pilot Study

    SciTech Connect

    Strecker, Ernst-Peter K.; Ostheim-Dzerowycz, Wladimir; Boos, Irene B.L.

    1998-03-15

    Purpose: To present the initial results of a new percutaneously implantable catheter port system (PIPS) used for long-term intraarterial infusion therapy in patients with severe ischemic limb disease. Methods: Ten patients with deep, extended ischemic ulcerations (all 10) and osteomyelitis (6/10) of the foot received intraarterial infusions of prostaglandine E{sub 1} and antibiotics, if indicated, via a new port catheter system with the port placed subcutaneously above the groin after percutaneous introduction and the catheter tip placed into the superficial or deep femoral artery. Results: Port implantation and repeated port access were uncomplicated. During the follow-up period (mean 11 months, range 1 week-50 months), port migration, leakage, or infection was not observed. Three catheters thrombosed and were opened by fibrinolysis with recombinant tissue plasminogen activator instilled via the port. Treatment success was achieved in 8 patients: relief from rest pain (8 patients), reduction of ulcer size (4/8), and complete healing (4/8). Limb savage rate was 80%. In 2 patients amputation could not be avoided. Conclusion: Selective long-term arterial infusion therapy presents a valuable therapeutic regimen for limb salvage. With the new catheter port system, repeated local intraarterial infusion is safe and simple.

  13. Port health control.

    PubMed

    Horner, J S

    1974-07-13

    Almost 950,000 of the 21 million passengers passing through London (Heathrow) Airport in 1973 were seen by the health control unit, which is run by the London Borough of Hillingdon. The unit provides 24-hour medical cover and its responsibilities include x-ray examination for tuberculosis and screening passengers from smallpox-infected areas. It is suggested that, in view of changing epidemiological patterns throughout the world, there is a need to modify existing procedures rather than to abandon them. The development of a follow-up system for tracing passengers at risk and improvements in presenting information about health risks to intending travellers are advocated. While such proposals might be opposed, they could be practicable.

  14. Enhancement of hERG channel activity by scFv antibody fragments targeted to the PAS domain

    PubMed Central

    Harley, Carol A.; Starek, Greg; Jones, David K.; Fernandes, Andreia S.; Robertson, Gail A.; Morais-Cabral, João H.

    2016-01-01

    The human human ether-à-go-go–related gene (hERG) potassium channel plays a critical role in the repolarization of the cardiac action potential. Changes in hERG channel function underlie long QT syndrome (LQTS) and are associated with cardiac arrhythmias and sudden death. A striking feature of this channel and KCNH channels in general is the presence of an N-terminal Per-Arnt-Sim (PAS) domain. In other proteins, PAS domains bind ligands and modulate effector domains. However, the PAS domains of KCNH channels are orphan receptors. We have uncovered a family of positive modulators of hERG that specifically bind to the PAS domain. We generated two single-chain variable fragments (scFvs) that recognize different epitopes on the PAS domain. Both antibodies increase the rate of deactivation but have different effects on channel activation and inactivation. Importantly, we show that both antibodies, on binding to the PAS domain, increase the total amount of current that permeates the channel during a ventricular action potential and significantly reduce the action potential duration recorded in human cardiomyocytes. Overall, these molecules constitute a previously unidentified class of positive modulators and establish that allosteric modulation of hERG channel function through ligand binding to the PAS domain can be attained. PMID:27516548

  15. Single port radical prostatectomy: current status.

    PubMed

    Martín, Oscar Darío; Azhar, Raed A; Clavijo, Rafael; Gidelman, Camilo; Medina, Luis; Troche, Nelson Ramirez; Brunacci, Leonardo; Sotelo, René

    2016-06-01

    The aim of this study is to analyze the current literature on single port radical prostatectomy (LESS-RP). Single port radical prostatectomy laparoendoscopic (LESS-RP) has established itself as a challenge for urological community, starting with the proposal of different approaches: extraperitoneal, transperitoneal and transvesical, initially described for laparoscopy and then laparoscopy robot-assisted. In order to improve the LESS-RP, new instruments, optical devices, trocars and retraction mechanisms have been developed. Advantages and disadvantages of LESS-RP are controversial, while some claim that it is a non-trustable approach, regarding the low cases number and technical difficulties, others acclaim that despite this facts some advantages have been shown and that previous described difficulties are being overcome, proving this is novel proposal of robotics platform, the Da Vinci SP, integrating the system into "Y". The LESS-RP approach gives us a new horizon and opens the door for rapid standardization of this technique. The few studies and short series available can be result of a low interest in the application of LESS-RP in prostate, probably because of the technical complexity that it requires. The new robotic platform, the da Vinci SP, shows that it is clear that the long awaited evolution of robotic technologies for laparoscopy has begun, and we must not lose this momentum.

  16. The effect of simultaneous contractions of ipsilateral muscles on changes in corticospinal excitability induced by paired associative stimulation (PAS).

    PubMed

    Kennedy, Niamh C; Carson, Richard G

    2008-11-07

    Consideration was given to means of increasing the reliability and muscle specificity of paired associative stimulation (PAS) by utilising the phenomenon of crossed-facilitation. Eight participants completed three separate sessions: isometric flexor contractions of the left wrist at 20% of maximum voluntary contraction (MVC) simultaneously with PAS (20s intervals; 14 min duration) delivered at the right median nerve and left primary motor cortex (M1); isometric contractions at 20% of MVC; and PAS only (14 min). Eight further participants completed two sessions of longer duration PAS (28 min): either alone or in conjunction with flexion contractions of the left wrist. Thirty motor potentials (MEPs) were evoked in the right flexor (rFCR) and extensor (rECR) carpi radialis muscles by magnetic stimulation of left M1 prior to the interventions, immediately post-intervention, and 10 min post-intervention. Both 14 and 28 min of combined PAS and (left wrist flexion) contractions resulted in reliable increases in rFCR MEP amplitude, which were not present in rECR. In the PAS only conditions, 14 min of stimulation gave rise to unreliable increases in MEP amplitudes in rFCR and rECR, whereas 28 min of PAS induced small (unreliable) changes only for rFCR. These results support the conclusion that changes in the excitability of the corticospinal pathway induced by PAS interact with those associated with contraction of the muscles ipsilateral to the site of cortical stimulation. Furthermore, focal contractions applied by the opposite limb increase the extent and muscle specificity of the induced changes in excitability associated with PAS.

  17. Evaluation of Fleeting Operations in Ports.

    DTIC Science & Technology

    1980-10-31

    industrial sites and their cargo handling I locations in the port area. 3) Based on (1) and (2) above, develop a fleeting evaluation technique which may be...within it. Phase 1, com- posed of four tasks, was designed to provide familiarity with respect to St. Louis port, harbor and fleeting operations. Task...1.1 reviewed the conventional professional literature of AAPA, ASCE, TRB and MARAD and the World Bank with respect to port and harbor design and

  18. Modeling Flow through a Lock Manifold Port

    DTIC Science & Technology

    2013-01-01

    computational model is to provide reliable loss coefficients. Energy losses for flow issuing from a port occur primarily in the submerged jet . The...computational flow model to determine the velocity and pressure distribution in a single-port manifold for a range of port-to-culvert discharge ...Engineers 2006). Navigation lock manifolds can be evaluated using analytical methods when the hydraulic characteristics associated with the manifold’s

  19. Laparoscopic Assisted Two Port Open Appendicectomy

    PubMed Central

    Golash, Vishwanath

    2008-01-01

    Objectives The laparoscopic appendicectomy can be performed using one to several ports. We present our experience of two port laparoscopic assisted open appendicectomy. The objective was to assess the results retrospectively in terms of complications and its limitations. Methods Between years 1998-2007, a two port laparoscopic assisted appendectomy was attempted in 2380 adult patients with suspected appendicitis. The patients with localized or generalized peritonitis were included. The appendicectomy was performed via an assisted two port method using 10 mm umbilical optical port and another 10 mm port in right iliac fossa. The children aged 12 and below and pregnant patients were excluded. All patients had their laparoscopic appendicectomy within 48 hours of admission. Results Two port laparoscopic assisted appendicectomy was successful in 86.9% of cases. Acute appendicitis was the cause of acute abdomen in 88.9% of the patients. The accessory port was required in 8.5% of patients to complete the appendicectomy and the conversion rate to open was 4.6%. The mean operation time was 25 minutes and the mean hospital stay was 1.5 days. The port site infection was seen in 14, bleeding in 20, parietal wall abscess in three cases and intra-abdominal abscesses in 4 patients. Conclusion This approach is simple, can be converted to total intracorporeal by inserting accessory port or to open appendicectomy when required and has advantage of full laparoscopy of abdomen. It has its limitations in cases of extreme obesity, thick mesentery, gangrenous appendix, very large and thick appendix, and difficulty in finding the appendix, control of bleeding, division of adhesions and to deal with other associated pathology. Cost was minimized by using non-disposable port. The overall morbidity was low. There were no specific complications related to this technique and incidence of port site infection was similar to other approaches of laparoscopic appendicectomy. PMID:22359707

  20. Severe Weather Guide - Mediterranean Ports. 7. Marseille

    DTIC Science & Technology

    1988-03-01

    Naval vessels normally utilize Avant Port Nord, the northern part of the Port, which is comprised of the following basins: Bassin Mirabeau , where the... Mirabeau -Mole de Leon Gourret GULF OF MARSEILLE ■43°16’N- NAUTICAL MILE SCALE 0 1 2 I I I 5°16’E...comprised of Avant Port Nord at the northern entrance, and the following basins: Bassin Mirabeau , Bassin Leon Bourret (Darse Sud), Bassin du President

  1. Port Security in the Persian Gulf

    DTIC Science & Technology

    2008-06-01

    national oil company , Saudi Aramco , claim to have invested massive resources in order to ensure the security of vital infrastructure. It is unclear...port security, ISPS, CSI, Saudi Arabia , United Arab Emirates, Iraq, maritime infrastructure, IMO, port facility, terrorism, smuggling, oil , fuel...petrochemicals and LPG.40 Petroleum exports shipped through Saudi Aramco -controlled ports are also significant. After Saudi oil is pumped from fields

  2. Complete three photon Hong-Ou-Mandel interference at a three port device.

    PubMed

    Mährlein, Simon; von Zanthier, Joachim; Agarwal, Girish S

    2015-06-15

    We report the possibility of completely destructive interference of three indistinguishable photons on a three port device providing a generalisation of the well known Hong-Ou-Mandel interference of two indistinguishable photons on a two port device. Our analysis is based on the underlying mathematical framework of SU(3) transformations rather than SU(2) transformations. We show the completely destructive three photon interference for a large range of parameters of the three port device and point out the physical origin of such interference in terms of the contributions from different quantum paths. As each output port can deliver zero to three photons the device generates higher dimensional entanglement. In particular, different forms of entangled states of qudits can be generated depending on the device parameters. Our system is different from a symmetric three port beam splitter which does not exhibit a three photon Hong-Ou-Mandel interference.

  3. Testing and Analysis of Sensor Ports

    NASA Technical Reports Server (NTRS)

    Zhang, M.; Frendi, A.; Thompson, W.; Casiano, M. J.

    2016-01-01

    This Technical Publication summarizes the work focused on the testing and analysis of sensor ports. The tasks under this contract were divided into three areas: (1) Development of an Analytical Model, (2) Conducting a Set of Experiments, and (3) Obtaining Computational Solutions. Results from the experiment using both short and long sensor ports were obtained using harmonic, random, and frequency sweep plane acoustic waves. An amplification factor of the pressure signal between the port inlet and the back of the port is obtained and compared to models. Comparisons of model and experimental results showed very good agreement.

  4. PortVis: A Tool for Port-Based Detection of Security Events

    SciTech Connect

    McPherson, J; Ma, K; Krystosk, P; Bartoletti, T; Christensen, M

    2004-06-29

    Most visualizations of security-related network data require large amounts of finely detailed, high-dimensional data. However, in some cases, the data available can only be coarsely detailed because of security concerns or other limitations. How can interesting security events still be discovered in data that lacks important details, such as IP addresses, network security alarms, and labels? In this paper, we discuss a system we have designed that takes very coarsely detailed data-basic, summarized information of the activity on each TCP port during each given hour-and uses visualization to help uncover interesting security events.

  5. Burkholderia cepacia complex Phage-Antibiotic Synergy (PAS): antibiotics stimulate lytic phage activity.

    PubMed

    Kamal, Fatima; Dennis, Jonathan J

    2015-02-01

    The Burkholderia cepacia complex (Bcc) is a group of at least 18 species of Gram-negative opportunistic pathogens that can cause chronic lung infection in cystic fibrosis (CF) patients. Bcc organisms possess high levels of innate antimicrobial resistance, and alternative therapeutic strategies are urgently needed. One proposed alternative treatment is phage therapy, the therapeutic application of bacterial viruses (or bacteriophages). Recently, some phages have been observed to form larger plaques in the presence of sublethal concentrations of certain antibiotics; this effect has been termed phage-antibiotic synergy (PAS). Those reports suggest that some antibiotics stimulate increased production of phages under certain conditions. The aim of this study is to examine PAS in phages that infect Burkholderia cenocepacia strains C6433 and K56-2. Bcc phages KS12 and KS14 were tested for PAS, using 6 antibiotics representing 4 different drug classes. Of the antibiotics tested, the most pronounced effects were observed for meropenem, ciprofloxacin, and tetracycline. When grown with subinhibitory concentrations of these three antibiotics, cells developed a chain-like arrangement, an elongated morphology, and a clustered arrangement, respectively. When treated with progressively higher antibiotic concentrations, both the sizes of plaques and phage titers increased, up to a maximum. B. cenocepacia K56-2-infected Galleria mellonella larvae treated with phage KS12 and low-dose meropenem demonstrated increased survival over controls treated with KS12 or antibiotic alone. These results suggest that antibiotics can be combined with phages to stimulate increased phage production and/or activity and thus improve the efficacy of bacterial killing.

  6. Burkholderia cepacia Complex Phage-Antibiotic Synergy (PAS): Antibiotics Stimulate Lytic Phage Activity

    PubMed Central

    Kamal, Fatima

    2014-01-01

    The Burkholderia cepacia complex (Bcc) is a group of at least 18 species of Gram-negative opportunistic pathogens that can cause chronic lung infection in cystic fibrosis (CF) patients. Bcc organisms possess high levels of innate antimicrobial resistance, and alternative therapeutic strategies are urgently needed. One proposed alternative treatment is phage therapy, the therapeutic application of bacterial viruses (or bacteriophages). Recently, some phages have been observed to form larger plaques in the presence of sublethal concentrations of certain antibiotics; this effect has been termed phage-antibiotic synergy (PAS). Those reports suggest that some antibiotics stimulate increased production of phages under certain conditions. The aim of this study is to examine PAS in phages that infect Burkholderia cenocepacia strains C6433 and K56-2. Bcc phages KS12 and KS14 were tested for PAS, using 6 antibiotics representing 4 different drug classes. Of the antibiotics tested, the most pronounced effects were observed for meropenem, ciprofloxacin, and tetracycline. When grown with subinhibitory concentrations of these three antibiotics, cells developed a chain-like arrangement, an elongated morphology, and a clustered arrangement, respectively. When treated with progressively higher antibiotic concentrations, both the sizes of plaques and phage titers increased, up to a maximum. B. cenocepacia K56-2-infected Galleria mellonella larvae treated with phage KS12 and low-dose meropenem demonstrated increased survival over controls treated with KS12 or antibiotic alone. These results suggest that antibiotics can be combined with phages to stimulate increased phage production and/or activity and thus improve the efficacy of bacterial killing. PMID:25452284

  7. Second Annual Maintenance, Inspection, and Test Report for PAS-1 Cask Certification for Shipping Payload B

    SciTech Connect

    KELLY, D.J.

    2000-10-09

    The Nuclear Packaging, Inc. (NuPac), PAS-1 cask is required to undergo annual maintenance and inspections to retain certification in accordance with U.S. Department of Energy (DOE) Certificate of Compliance USA/9184B(U) (Appendix A). The packaging configuration being tested and maintained is the NuPac PAS-1 cask for Payload B. The intent of the maintenance and inspections is to ensure the packaging remains in unimpaired physical condition. Two casks, serial numbers 2162-026 and 2162-027, were maintained, inspected, and tested at the 306E Development, Fabrication, and Test Laboratory, located at the Hanford Site's 300 Area. Waste Management Federal Services, Inc. (WMFS), a subsidiary of GTS Duratek, was in charge of the maintenance and testing. Cogema Engineering Corporation (Cogema) directed the operations in the test facility. The maintenance, testing, and inspections were conducted successfully with both PAS-1 casks. The work conducted on the overpacks included weighing, gasket replacement, and plastic pipe plug and foam inspections. The work conducted on the secondary containment vessel (SCV) consisted of visual inspection of the vessel and threaded parts (i.e., fasteners), visual inspection of sealing surfaces, replacement of O-ring seals, and a helium leak test. The work conducted on the primary containment vessel (PCV) consisted of visual inspection of the vessel and threaded parts (i.e., fasteners), visual inspection of sealing surfaces, replacement of O-ring seals, dimensional inspection of the vessel bottom, a helium leak test, and dye penetrant inspection of the welds. The vermiculite material used in the cask rack assembly was replaced.

  8. 19 CFR 101.3 - Customs service ports and ports of entry.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... require. (b) List of Ports of Entry and Service Ports. The following is a list of Customs Ports of Entry.... 7632, June 15, 1937 (2 FR 1245). Roseau E.O. 7632, June 15, 1937 (2 FR 1245). Warroad Mississippi... 3403); including territory described in T.D. 67-56. Spirit of St. Louis Airport Including...

  9. 19 CFR 101.3 - Customs service ports and ports of entry.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... require. (b) List of Ports of Entry and Service Ports. The following is a list of Customs Ports of Entry.... 7632, June 15, 1937 (2 FR 1245). Roseau E.O. 7632, June 15, 1937 (2 FR 1245). Warroad Mississippi... 3403); including territory described in T.D. 67-56. Spirit of St. Louis Airport Including...

  10. 19 CFR 101.3 - Customs service ports and ports of entry.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... require. (b) List of Ports of Entry and Service Ports. The following is a list of Customs Ports of Entry.... 7632, June 15, 1937 (2 FR 1245). Roseau E.O. 7632, June 15, 1937 (2 FR 1245). Warroad Mississippi... 3403); including territory described in T.D. 67-56. Spirit of St. Louis Airport Including...

  11. 19 CFR 101.3 - Customs service ports and ports of entry.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... require. (b) List of Ports of Entry and Service Ports. The following is a list of Customs Ports of Entry.... 7632, June 15, 1937 (2 FR 1245). Roseau E.O. 7632, June 15, 1937 (2 FR 1245). Warroad Mississippi... 3403); including territory described in T.D. 67-56. Spirit of St. Louis Airport Including...

  12. 19 CFR 101.3 - Customs service ports and ports of entry.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... require. (b) List of Ports of Entry and Service Ports. The following is a list of Customs Ports of Entry.... 7632, June 15, 1937 (2 FR 1245). Roseau E.O. 7632, June 15, 1937 (2 FR 1245). Warroad Mississippi... 3403); including territory described in T.D. 67-56. Spirit of St. Louis Airport Including...

  13. Protective effects of ebselen (Ebs) and para-aminosalicylic acid (PAS) against manganese (Mn)-induced neurotoxicity

    SciTech Connect

    Marreilha dos Santos, A.P.; Lucas, Rui L.; Andrade, Vanda; Mateus, M. Luísa; Milatovic, Dejan; Aschner, Michael; Batoreu, M. Camila

    2012-02-01

    Chronic, excessive exposure to manganese (Mn) may induce neurotoxicity and cause an irreversible brain disease, referred to as manganism. Efficacious therapies for the treatment of Mn are lacking, mandating the development of new interventions. The purpose of the present study was to investigate the efficacy of ebselen (Ebs) and para-aminosalicylic acid (PAS) in attenuating the neurotoxic effects of Mn in an in vivo rat model. Exposure biomarkers, inflammatory and oxidative stress biomarkers, as well as behavioral parameters were evaluated. Co-treatment with Mn plus Ebs or Mn plus PAS caused a significant decrease in blood and brain Mn concentrations (compared to rats treated with Mn alone), concomitant with reduced brain E{sub 2} prostaglandin (PGE{sub 2}) and enhanced brain glutathione (GSH) levels, decreased serum prolactin (PRL) levels, and increased ambulation and rearing activities. Taken together, these results establish that both PAS and Ebs are efficacious in reducing Mn body burden, neuroinflammation, oxidative stress and locomotor activity impairments in a rat model of Mn-induced toxicity. -- Highlights: ► The manuscript is unique in its approach to the neurotoxicity of Mn. ► The manuscript incorporates molecular, cellular and functional (behavioral) analyses. ► Both PAS and Ebs are effective in restoring Mn behavioral function. ► Both PAS and Ebs are effective in reducing Mn-induced oxidative stress. ► Both PAS and Ebs led to a decrease in Mn-induced neuro-inflammation.

  14. Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.

    PubMed

    Scheuermann, Thomas H; Tomchick, Diana R; Machius, Mischa; Guo, Yan; Bruick, Richard K; Gardner, Kevin H

    2009-01-13

    The hypoxia-inducible factor (HIF) basic helix-loop-helix Per-aryl hydrocarbon receptor nuclear translocator (ARNT)-Sim (bHLH-PAS) transcription factors are master regulators of the conserved molecular mechanism by which metazoans sense and respond to reductions in local oxygen concentrations. In humans, HIF is critically important for the sustained growth and metastasis of solid tumors. Here, we describe crystal structures of the heterodimer formed by the C-terminal PAS domains from the HIF2alpha and ARNT subunits of the HIF2 transcription factor, both in the absence and presence of an artificial ligand. Unexpectedly, the HIF2alpha PAS-B domain contains a large internal cavity that accommodates ligands identified from a small-molecule screen. Binding one of these ligands to HIF2alpha PAS-B modulates the affinity of the HIF2alpha:ARNT PAS-B heterodimer in vitro. Given the essential role of PAS domains in forming active HIF heterodimers, these results suggest a presently uncharacterized ligand-mediated mechanism for regulating HIF2 activity in endogenous and clinical settings.

  15. Artificial ligand binding within the HIF2[alpha] PAS-B domain of the HIF2 transcription factor

    SciTech Connect

    Scheuermann, Thomas H.; Tomchick, Diana R.; Machius, Mischa; Guo, Yan; Bruick, Richard K.; Gardner, Kevin H.

    2009-05-12

    The hypoxia-inducible factor (HIF) basic helix-loop-helix Per-aryl hydrocarbon receptor nuclear translocator (ARNT)-Sim (bHLH-PAS) transcription factors are master regulators of the conserved molecular mechanism by which metazoans sense and respond to reductions in local oxygen concentrations. In humans, HIF is critically important for the sustained growth and metastasis of solid tumors. Here, we describe crystal structures of the heterodimer formed by the C-terminal PAS domains from the HIF2{alpha} and ARNT subunits of the HIF2 transcription factor, both in the absence and presence of an artificial ligand. Unexpectedly, the HIF2{alpha} PAS-B domain contains a large internal cavity that accommodates ligands identified from a small-molecule screen. Binding one of these ligands to HIF2{alpha} PAS-B modulates the affinity of the HIF2{alpha}:ARNT PAS-B heterodimer in vitro. Given the essential role of PAS domains in forming active HIF heterodimers, these results suggest a presently uncharacterized ligand-mediated mechanism for regulating HIF2 activity in endogenous and clinical settings.

  16. Development of a New Subclavian Arterial Infusion Chemotherapy Method for Locally or Recurrent Advanced Breast Cancer Using an Implanted Catheter-Port System After Redistribution of Arterial Tumor Supply

    SciTech Connect

    Takizawa, Kenji Shimamoto, Hiroshi Ogawa, Yukihisa Yoshimatsu, Misako Yagihashi, Kunihiro Nakajima, Yasuo; Kitanosono, Takashi

    2009-09-15

    Locally or recurrent advanced breast cancers can receive arterial blood supply from various arteries, such as the internal thoracic artery (ITA), the lateral thoracic artery, and the other small arterial branches originating from the subclavian artery. Failure to catheterize and subsequent formation of collateral arterial blood supply from various arteries are some of the reasons why the response to conventional selective transarterial infusion chemotherapy is limited and variable. To overcome this problem, we developed a new subclavian arterial infusion chemotherapy method using an implanted catheter-port system after redistribution of arterial tumor blood supply by embolizing the ITA. We named this technique ('redistributed subclavian arterial infusion chemotherapy' (RESAIC)). Using RESAIC, patients can be treated on an outpatient basis for extended periods of time. Eleven patients underwent RESAIC, and the complete remission and partial response rate in 10 evaluable patients was 90%: complete remission [CR] n = 4, partial remission n = 4, stable disease n = 1, and not evaluable n = 1. Three of four patients with CR had no distant metastasis, and modified radical mastectomy was performed 1 month after conclusion of RESAIC. The resected specimens showed no residual cancer cells, and pathologically confirmed complete remission was diagnosed in each of these cases. Although temporary grade-3 myelosuppression was seen in three patients who were previously treated by systemic chemotherapy, there was no other drug-induced toxicity or procedure-related complications. RESAIC produced a better response and showed no major complications compared with other studies despite the advanced stage of the cancers.

  17. Climate variability and Port wine quality

    NASA Astrophysics Data System (ADS)

    Gouveia, Celia; Liberato, Margarida L. R.; Trigo, Ricardo M.; Dacamara, Carlos

    2010-05-01

    Recent warming trends for Portugal have been found to be steepest in winter and spring and more pronounced for minimum than for maximum values of temperature (Miranda et al, 2002). These trends and associated changes in temperature and precipitation regimes may exert strong influences on agriculture systems. For instance, high values of the North Atlantic Oscillation (NAO) index have been shown to significantly reduce precipitation over Iberia and therefore induce low yield wheat crops in Portugal (Gouveia and Trigo, 2006). Port wine is produced from grapes grown in selected areas of the Douro valley, the so-called Região Demarcada do Douro, the first wine-producing region of the world (dating from 1758). A vintage wine is made from grapes that were grown and harvested in a single specified year and is classified as such because of the above average quality, a status that is attributed by Port houses in their best years. The Douro region presents distinctive climatic, topographic and soil characteristics. While the latest factors are fixed in time, the former may considerably change from year to year, exposing the Port wine productions to a large risk associated to interannual and intra-seasonal climatic variations. It is therefore to be expected that high quality wines are generally associated to optimum climatic conditions. In this work we have performed an analysis of the distinct behaviour of several meteorological fields in vintage versus non-vintage years. The relative importance of maximum and minimum temperature, precipitation and frost days is assessed for each individual month of the vegetative cycle and their importance to a high quality wine year is evaluated. Composites of 500 hPa geopotential height and sea level pressure fields over the Euro Atlantic region are also compared for vintage and non-vintage years. Results reveal a strong dependence of vintage production on maximum temperature and precipitation during spring and summer (the growing season

  18. National Conversation on Ports: Webinar Slides and Transcripts

    EPA Pesticide Factsheets

    To exchange views and develop a shared understanding of the challenges and opportunities of ports and port communities, EPA's Office of Transportation and Air Quality is hosting a series of webinars, bringing together port stakeholders.

  19. Contextual view of ILWU Hall, facing northwest with commercial port ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Contextual view of ILWU Hall, facing northwest with commercial port buildings visible in the background - International Longshoremen's & Warehousemen's Union Hall, Naval Civil Engineering Laboratory, Port Hueneme Road, Port Hueneme, Ventura County, CA

  20. Ports Primer: 3.3 Federal and International Governance

    EPA Pesticide Factsheets

    State and local governments are important players in port governance and in oversight of transportation projects that may affect ports. Private corporations may also play a role if they lease or own a terminal at a port.

  1. Solid Rocket Booster Hydraulic Pump Port Cap Joint Load Testing

    NASA Technical Reports Server (NTRS)

    Gamwell, W. R.; Murphy, N. C.

    2004-01-01

    The solid rocket booster uses hydraulic pumps fabricated from cast C355 aluminum alloy, with 17-4 PH stainless steel pump port caps. Corrosion-resistant steel, MS51830 CA204L self-locking screw thread inserts are installed into C355 pump housings, with A286 stainless steel fasteners installed into the insert to secure the pump port cap to the housing. In the past, pump port cap fasteners were installed to a torque of 33 Nm (300 in-lb). However, the structural analyses used a significantly higher nut factor than indicated during tests conducted by Boeing Space Systems. When the torque values were reassessed using Boeing's nut factor, the fastener preload had a factor of safety of less than 1, with potential for overloading the joint. This paper describes how behavior was determined for a preloaded joint with a steel bolt threaded into steel inserts in aluminum parts. Finite element models were compared with test results. For all initial bolt preloads, bolt loads increased as external applied loads increased. For higher initial bolt preloads, less load was transferred into the bolt, due to external applied loading. Lower torque limits were established for pump port cap fasteners and additional limits were placed on insert axial deformation under operating conditions after seating the insert with an initial preload.

  2. 50 CFR 24.12 - Designated ports.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., Florida Pensacola, Florida Cape Canaveral, Florida Port Everglades, Florida Tampa, Florida West Palm Beach...: Nogales, Arizona Los Angeles, California San Diego, California San Francisco, California Miami, Florida Orlando, Florida Honolulu, Hawaii New Orleans, Louisiana Hoboken, New Jersey (Port of New York)...

  3. U.S. Offshore Wind Port Readiness

    SciTech Connect

    C. Elkinton, A. Blatiak, H. Ameen

    2013-10-13

    This study will aid decision-makers in making informed decisions regarding the choice of ports for specific offshore projects, and the types of investments that would be required to make individual port facilities suitable to serve offshore wind manufacturing, installation and/or operations.

  4. Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression

    NASA Astrophysics Data System (ADS)

    Makino, Yuichi; Cao, Renhai; Svensson, Kristian; Bertilsson, Göran; Asman, Mikael; Tanaka, Hirotoshi; Cao, Yihai; Berkenstam, Anders; Poellinger, Lorenz

    2001-11-01

    Alteration of gene expression is a crucial component of adaptive responses to hypoxia. These responses are mediated by hypoxia-inducible transcription factors (HIFs). Here we describe an inhibitory PAS (Per/Arnt/Sim) domain protein, IPAS, which is a basic helix-loop-helix (bHLH)/PAS protein structurally related to HIFs. IPAS contains no endogenous transactivation function but demonstrates dominant negative regulation of HIF-mediated control of gene expression. Ectopic expression of IPAS in hepatoma cells selectively impairs induction of genes involved in adaptation to a hypoxic environment, notably the vascular endothelial growth factor (VEGF) gene, and results in retarded tumour growth and tumour vascular density in vivo. In mice, IPAS was predominantly expressed in Purkinje cells of the cerebellum and in corneal epithelium of the eye. Expression of IPAS in the cornea correlates with low levels of expression of the VEGF gene under hypoxic conditions. Application of an IPAS antisense oligonucleotide to the mouse cornea induced angiogenesis under normal oxygen conditions, and demonstrated hypoxia-dependent induction of VEGF gene expression in hypoxic corneal cells. These results indicate a previously unknown mechanism for negative regulation of angiogenesis and maintenance of an avascular phenotype.

  5. JPCam: Development of a 1.2 Gpixel Camera for the J-PAS Survey

    NASA Astrophysics Data System (ADS)

    Marín-Franch, A.; Taylor, K.; Santoro, F. G.; Laporte, R.; Cepa, J.; Lasso-Cabrera, N.; Yanes-Díaz, A.; Cenarro, A. J.; Cristobal-Hornillos, D.; Ederoclite, A.; Moles, M.; Varela, J.; Vázquez-Ramió, H.; Antón, J. L.; Bello, R.; Civera, T.; Castillo, J.,; Chueca, S.; Guillén-Civera, L.; Hernández-Fuertes, J.; Igual, R.; Íniguez, C.; López-Alegre, G.; López-Sainz, A.; Nevot, C.; Milla, R.; Muniesa, D.; Pe, A.; Rueda-Teruel, R.; Rueda-Teruel, F.; Sánchez, J.; Benitez, N.; Dupke, R.; Fernández-Soto, A.; Mendes de Oliveira, C.; Sodré, L.

    2017-03-01

    To carry out J-PAS survey, the JST/T250 telescope at the Observatorio Astrofósico de Javalambre (OAJ) is equipped with JPCam, a panoramic camera designed to exploit survey capabilities of the telescope. JPCam is a direct imaging instrument designed to work in a fast convergent beam at the telescope’s Cassegrain focus. It is based on state-of-the-art, high efficiency, low noise 9.2k-by-9.2k, 10μm pixel CCDs specially developed by e2v for JPCam. The instrument is equipped with a 1.2Gpixel mosaic of 14 CCDs providing a useful FoV of 4.7 deg2 (67% focal plane coverage) with a plate scale of 0.2267 arcsec/pix. Moreover, JPCam includes 12 auxiliary detectors for auto-guiding and wave front sensing purposes. JPCam is completed with an innovative set of 59 optical filters specifically designed to perform accurate BAO measurements, main science driver of J-PAS.

  6. 38. FLAG/ADMIRAL BRIDGE PORT LOOKING TO STARBOARD SHOWING RADAR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    38. FLAG/ADMIRAL BRIDGE - PORT LOOKING TO STARBOARD SHOWING RADAR SCOPE, ADMIRAL'S CHAIR, GYRO REPEATER AND VARIOUS COMMUNICATION SYSTEMS. - U.S.S. HORNET, Puget Sound Naval Shipyard, Sinclair Inlet, Bremerton, Kitsap County, WA

  7. Detail view of the port side of the payload bay ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of the port side of the payload bay of the Orbiter Discovery. This view shows Remote Manipulator System, Canadarm, sensors in the center of the image and a close-up view of a small segment of the orbiter's radiator panel. This photograph was taken in the Orbiter Processing Facility at the Kennedy Space Center. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  8. Detail view of the forward section, port side, of the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of the forward section, port side, of the Orbiter Discovery from an elevated platform in the Vehicle Assembly Building at NASA's Kennedy Space Center. Note the removal of the Forward Reaction Control System Module from the nose section, the ground-support window covers and the strongback attached to the payload bay door. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  9. Extended Range Underwater Loudhailer for Port Security Applications

    DTIC Science & Technology

    2006-06-01

    CG) has developed an Integrated Anti- swimmer System (IAS) to aid enforcement of security zones around high-value maritime assets. The IAS includes...water’s surface, primarily from combat swimmers and divers. The CG’s Underwater Port Security (UPSec) mission requires the ability to detect, track...locate, identify, and interdict potentially hostile swimmers and divers. An Integrated Anti- swimmer System (IAS) has been developed that

  10. Sequences that direct subcellular traffic of the Drosophila methoprene-tolerant protein (MET) are located predominantly in the PAS domains.

    PubMed

    Greb-Markiewicz, Beata; Orłowski, Marek; Dobrucki, Jerzy; Ożyhar, Andrzej

    2011-10-15

    Methoprene-tolerant protein (MET) is a key mediator of antimetamorphic signaling in insects. MET belongs to the family of bHLH-PAS transcription factors which regulate gene expression and determine essential physiological and developmental processes. The ability of many bHLH-PAS proteins to carry out their functions is related to the patterns of intracellular trafficking, which are determined by specific sequences and indicate that a nuclear localization signal (NLS) or a nuclear export signal (NES) is present and active. Therefore, the identification of NLS and NES signals is fundamental in order to understand the intracellular signaling role of MET. Nevertheless, data on the intracellular trafficking of MET are inconsistent, and until now there hasn't been any data on potential NLS and NES sequences. To analyze the trafficking of MET we designed a number of expression vectors encoding full-length MET, as well as various derivatives, that were fused to yellow fluorescent protein (YFP). Confocal microscopy analysis of the subcellular distribution of YFP-MET indicated that while this protein was localized mainly in the nucleus, it was also observed in the cytoplasm. This suggested the presence of both an NLS and NES in MET. Our work has shown that each of the two PAS domains of MET (PAS-A and PAS-B, respectively) contain one NLS and one NES sequence. Additional NES activity was present in the C-terminal fragment. The NLS activity located in PAS-B was dependent on the presence of juvenile hormone (JH), the potential ligand for MET. In contrast to this, JH didn't seem to be required for the NLS in PAS-A to be active. However, on the basis of current knowledge about the function of PAS-A in other bHLH-PAS proteins, we suggest there might be other proteins that control the activity of the NLS and possibly the NES located in the PAS-A of MET. Thus, the intracellular trafficking of MET seems to be regulated by a rather complicated network of different factors.

  11. Integrated circuit test-port architecture and method and apparatus of test-port generation

    DOEpatents

    Teifel, John

    2016-04-12

    A method and apparatus are provided for generating RTL code for a test-port interface of an integrated circuit. In an embodiment, a test-port table is provided as input data. A computer automatically parses the test-port table into data structures and analyzes it to determine input, output, local, and output-enable port names. The computer generates address-detect and test-enable logic constructed from combinational functions. The computer generates one-hot multiplexer logic for at least some of the output ports. The one-hot multiplexer logic for each port is generated so as to enable the port to toggle between data signals and test signals. The computer then completes the generation of the RTL code.

  12. Entry/Exit Port testing, test report

    SciTech Connect

    Winkelman, R.H.

    1993-05-01

    The Waste Receiving and Processing Module I (WRAP-1) facility must have the ability to allow 55-gallon drums to enter and exit glovebox enclosures. An Entry/Exit Port (Appendix 1, Figure 1), designed by United Engineers and Constructors (UE&C), is one method chosen for drum transfer. The Entry/Exit Port is to be used for entry of 55-gallon drums into both process entry gloveboxes, exit of 55-gallon drum waste pucks from the low-level waste (LLW) glovebox, and loadout of waste from the restricted waste management glovebox. The Entry/Exit Port relies on capture velocity air flow and a neoprene seal to provide alpha confinement when the Port is in the open and closed positions, respectively. Since the glovebox is in a slight vacuum, air flow is directed into the glovebox through the space between the overpack drum and glovebox floor. The air flow is to direct any airborne contamination into the glovebox. A neoprene seal is used to seal the Port door to the glovebox floor, thus maintaining confinement in the closed position. Entry/Exit Port testing took place February 17, 1993, through April 14, 1993, in the 305 building of Westinghouse Hanford Company. Testing was performed in accordance with the Entry/Exit Port Testing Test Plan, document number WHC-SD-WO26-TP-005. A prototype Entry/Exit Port built at the Hanford Site was tested using fluorescent paint pigment and smoke candles as simulant contaminants. This test report is an interim test report. Further developmental testing is required to test modifications made to the Port as the original design of the Port did not provide complete confinement during all stages of operation.

  13. Application of FTIR-PAS and Raman spectroscopies for the determination of organic matter in farmland soils.

    PubMed

    Xing, Zhe; Du, Changwen; Tian, Kang; Ma, Fei; Shen, Yazhen; Zhou, Jianmin

    2016-09-01

    In soil analysis, Raman spectroscopy is not as widely used as infrared spectroscopy mainly owing to fluorescence interferences. This paper investigated the feasibility of Fourier-transform infrared photoacoustic (FTIR-PAS) and Raman spectroscopies for predicting soil organic matter (SOM) using partial least squares regression (PLSR) analysis. 194 farmland soil samples were collected and scanned with FTIR and Raman spectrometers in the spectral range of 4000-400cm(-1) and 180-3200cm(-1), respectively. For the PLSR models, the combined dataset was split into 146 samples as the calibration set (75%) and 48 samples as the validation set (25%). The optimal number of analytical factors was determined using a leave-one-out cross-validation. The results showed that SOM could be predicted using FTIR-PAS and Raman spectroscopies independently, with R(2)>0.70 and RPD>1.8 for the validation sets. In comparison to the single applications of FTIR-PAS and Raman spectroscopies, accurate prediction of SOM was made by combining FTIR-PAS and Raman spectroscopies, with R(2)=0.81 and RPD=2.18 for the validation sets. By statistically assessing large amounts of PLS models, model-population analysis confirmed that the accuracy of the PLS model can be increased by combining FTIR-PAS and Raman spectroscopies. In conclusion, the combination of FTIR-PAS and Raman spectroscopies is a promising alternative for soil characterization, especially for the prediction of SOM, owing to the availability of complementary information from both FTIR-PAS (polar vibrations) and Raman spectroscopy (non-polar vibrations).

  14. Hardware and software facilities for the J-PAS and J-PLUS surveys archiving, processing and data publication

    NASA Astrophysics Data System (ADS)

    Cristóbal-Hornillos, D.; Varela, J.; Ederoclite, A.; Vázquez Ramió, H.; López-Sainz, A.; Hernández-Fuertes, J.; Civera, T.; Muniesa, D.; Moles, M.; Cenarro, A. J.; Marín-Franch, A.; Yanes-Díaz, A.

    2015-05-01

    The Observatorio Astrofísico de Javalambre consists of two main telescopes: JST/T250, a 2.5 m telescope with a FoV of 3 deg, and JAST/T80, a 83 cm with a 2 deg FoV. JST/T250 will be devoted to complete the Javalambre-PAU Astronomical Survey (J-PAS). It is a photometric survey with a system of 54 narrow-band plus 3 broad-band filters covering an area of 8500°^2. The JAST/T80 will perform the J-PLUS survey, covering the same area in a system of 12 filters. This contribution presents the software and hardware architecture designed to store and process the data. The processing pipeline runs daily and it is devoted to correct instrumental signature on the science images, to perform astrometric and photometric calibration, and the computation of individual image catalogs. In a second stage, the pipeline performs the combination of the tile mosaics and the computation of final catalogs. The catalogs are ingested in as Scientific database to be provided to the community. The processing software is connected with a management database to store persistent information about the pipeline operations done on each frame. The processing pipeline is executed in a computing cluster under a batch queuing system. Regarding the storage system, it will combine disk and tape technologies. The disk storage system will have capacity to store the data that is accessed by the pipeline. The tape library will store and archive the raw data and earlier data releases with lower access frequency.

  15. The Pterional Port in Dual-Port Endoscopy: A 2D and 3D Cadaveric Study

    PubMed Central

    Beer-Furlan, André; Evins, Alexander I.; Rigante, Luigi; Anichini, Giulio; Stieg, Philip E.; Bernardo, Antonio

    2014-01-01

    Objective We propose a novel dual-port endonasal and pterional endoscopic approach targeting midline lesions of the anterior cranial fossa with lateral extension beyond the optic nerve. Methods Ten dual-port approaches were performed on five cadaveric heads. All specimens underwent an endoscopic transtuberculum/transplanum approach followed by placement of a pterional port. The endonasal port was combined with an endoscopic extradural pterional keyhole craniectomy. The pterional port was placed at the intersection of the sphenoparietal and coronal sutures. The extradural space was explored using two-dimensional and three-dimensional endoscopes. Results The superolateral access provided by the pterional port may improve the ability to achieve a gross total resection of tumors with lateral extensions. The complete opening of the optic canal achieved through the dual-port approach may enable resection of the intracanalicular portion of a tumor, a crucial step in improvement of visual function and reduction of tumor recurrence. Conclusion The pterional port may enhance control of midline anterior skull base lesions with lateral extension beyond the optic nerve and optic canal. Dual-port endoscopy maintains minimally invasiveness and dramatically increases the working limits and control of anatomical structures well beyond what is attainable through single-port neuroendoscopy. PMID:25685654

  16. Stakeholder identification of advanced technology opportunities at international ports of entry

    SciTech Connect

    Parker, S.K.; Icerman, L.

    1997-01-01

    As part of the Advanced Technologies for International and Intermodal Ports of Entry (ATIPE) Project, a diverse group of stakeholders was engaged to help identify problems experienced at inland international border crossings, particularly those at the US-Mexican border. The fundamental issue at international ports of entry is reducing transit time through the required documentation and inspection processes. Examples of other issues or problems, typically manifested as time delays at border crossings, repeatedly mentioned by stakeholders include: (1) lack of document standardization; (2) failure to standardize inspection processes; (3) inadequate information and communications systems; (4) manual fee and tariff collection; (5) inconsistency of processes and procedures; and (6) suboptimal cooperation among governmental agencies. Most of these issues can be addressed to some extent by the development of advanced technologies with the objective of allowing ports of entry to become more efficient while being more effective. Three categories of technologies were unambiguously of high priority to port of entry stakeholders: (1) automated documentation; (2) systems integration; and (3) vehicle and cargo tracking. Together, these technologies represent many of the technical components necessary for pre-clearance of freight approaching international ports of entry. Integration of vehicle and cargo tracking systems with port of entry information and communications systems, as well as existing industry legacy systems, should further enable border crossings to be accomplished consistently with optimal processing times.

  17. Recognition of faux pas by normally developing children and children with Asperger syndrome or high-functioning autism.

    PubMed

    Baron-Cohen, S; O'Riordan, M; Stone, V; Jones, R; Plaisted, K

    1999-10-01

    Most theory of mind (ToM) tests are designed for subjects with a mental age of 4-6 years. There are very few ToM tests for subjects who are older or more able than this. We report a new test of ToM, designed for children 7-11 years old. The task involves recognizing faux pas. Study 1 tested 7-9, and 11-year-old normal children. Results showed that the ability to detect faux pas developed with age and that there was a differential developmental profile between the two sexes (female superiority). Study 2 tested children with Asperger syndrome (AS) or high-functioning autism (HFA), selected for being able to pass traditional 4- to 6-year level (first- and second-order) false belief tests. Results showed that whereas normal 9- to 11-year-old children were skilled at detecting faux pas, children with AS or HFA were impaired on this task. Study 3 reports a refinement in the test, employing control stimuli. This replicated the results from Study 2. Some patients with AS or HFA were able to recognize faux pas but still produced them. Future research should assess faux pas production.

  18. [Evaluation of the website of the Nord-Pas-de-Calais regional pharmacovigilance center].

    PubMed

    Rochoy, Michaël; Béné, Johana; Messaadi, Nassir; Auffret, Marine; Gautier, Sophie

    2016-06-01

    We posted the Nord-Pas-de-Calais regional pharmacovigilance center website and distributed a survey to its potential users between August 2014 and October 2014 (135 general practitioners, 45 pharmacists, 14 patients). Satisfaction was 7.3±1.6 out of 10 points for the visual aspect, 7.8±1.5 out of 10 points for navigation and 7.6±1.4 out of 10 points for content. The website was declared useful by 98% respondents, particularly for the reporting of adverse drugs reactions (89%).

  19. HRF, a putative basic helix-loop-helix-PAS-domain transcription factor is closely related to hypoxia-inducible factor-1 alpha and developmentally expressed in blood vessels.

    PubMed

    Flamme, I; Fröhlich, T; von Reutern, M; Kappel, A; Damert, A; Risau, W

    1997-04-01

    Transcription factors of the bHLH-PAS protein family are important regulators of developmental processes such as neurogenesis and tracheal development in invertebrates. Recently a bHLH-PAS protein, named trachealess (trl) was identified as a master regulator of tracheogenesis. Hypoxia-inducible factor, HIF-1 alpha, is a vertebrate relative of trl which is likely to be involved in growth of blood vessels by the induction of vascular endothelial growth factor (VEGF) in response to hypoxia. In the present study we describe mRNA cloning and mRNA expression pattern of mouse HIF-related factor (HRF), a novel close relative of HIF-1 alpha which is expressed most prominently in brain capillary endothelial cells and other blood vessels as well as in bronchial epithelium in the embryo and the adult. In addition, smooth muscle cells of the uterus, neurons, brown adipose tissue and various epithelial tissues express HRF mRNA as well. High expression levels of HRF mRNA in embryonic choroid plexus and kidney glomeruli, places where VEGF is highly expressed, suggest a role of this factor in VEGF gene activation similar to that of HIF-1 alpha. Given the similarity between morphogenesis of the tracheal system and the vertebrate vascular system, the expression pattern of HRF in the vasculature and the bronchial tree raises the possibility that this family of transcription factors may be involved in tubulogenesis.

  20. The structure of the periplasmic ligand-binding domain of the sensor kinase CitA reveals the first extracellular PAS domain.

    PubMed

    Reinelt, Stefan; Hofmann, Eckhard; Gerharz, Tanja; Bott, Michael; Madden, Dean R

    2003-10-03

    The integral membrane sensor kinase CitA of Klebsiella pneumoniae is part of a two-component signal transduction system that regulates the transport and metabolism of citrate in response to its environmental concentration. Two-component systems are widely used by bacteria for such adaptive processes, but the stereochemistry of periplasmic ligand binding and the mechanism of signal transduction across the membrane remain poorly understood. The crystal structure of the CitAP periplasmic sensor domain in complex with citrate reveals a PAS fold, a versatile ligand-binding structural motif that has not previously been observed outside the cytoplasm or implicated in the transduction of conformational signals across the membrane. Citrate is bound in a pocket that is shared among many PAS domains but that shows structural variation according to the nature of the bound ligand. In CitAP, some of the citrate contact residues are located in the final strand of the central beta-sheet, which is connected to the C-terminal transmembrane helix. These secondary structure elements thus provide a potential conformational link between the periplasmic ligand binding site and the cytoplasmic signaling domains of the receptor.

  1. Report of the Evaluation Meeting on the Caribbean Information System (Port-of-Spain, Trinidad and Tobago, July 6-8, 1983).

    ERIC Educational Resources Information Center

    United Nations Economic Commission for Latin America, Port-of-Spain (Trinadad). Caribbean Documentation Centre.

    This publication outlines the activities and impact of the Caribbean Information System for Economic and Social Planning (CARISPLAN), as reported by representatives of 16 Caribbean nations and various regional organizations. A copy of the meeting agenda and other introductory material are followed by brief summaries of reports from representatives…

  2. Dos, a heme-binding PAS protein from Escherichia coli, is a direct oxygen sensor.

    PubMed

    Delgado-Nixon, V M; Gonzalez, G; Gilles-Gonzalez, M A

    2000-03-14

    A direct sensor of O(2), the Dos protein, has been found in Escherichia coli. Previously, the only biological sensors known to respond to O(2) by direct and reversible binding were the FixL proteins of Rhizobia. A heme-binding region in Dos is 60% homologous to the O(2)-sensing PAS domain of the FixL protein, but the remainder of Dos does not resemble FixL. Specifically, the C-terminal domain of Dos, presumed to be a regulatory partner that couples to its heme-binding domain, is not a histidine kinase but more closely resembles a phosphodiesterase. The absorption spectra of Dos indicate that both axial positions of the heme iron are coordinated to side chains of the protein. Nevertheless, O(2) and CO bind to Dos with K(d) values of 13 and 10 microM, respectively, indicating a strong discrimination against CO binding. Association rate constants for binding of O(2) (3 mM(-)(1) s(-)(1)), CO (1 mM(-)(1) s(-)(1)) and even NO (2 mM(-)(1) s(-)(1)) are extraordinarily low and very similar. Displacement of an endogenous ligand, probably Met 95, from the heme iron in Dos triggers a conformational change that alters the activity of the enzymatic domain. This sensing mechanism differs from that of FixL but resembles that of the CO sensor CooA of Rhodospirillum rubrum. Overall the results provide evidence for a heme-binding subgroup of PAS-domain proteins whose working range, signaling mechanisms, and regulatory partners can vary considerably.

  3. Morphological evaluation of canine platelets on Giemsa- and PAS-stained blood smears.

    PubMed

    Halmay, Dóra; Sótonyi, P; Vajdovich, P; Gaál, T

    2005-01-01

    The morphology of canine platelets (changes in size, shape, staining characteristics, degree of activation and clump formation, distribution of granules, appearance of vacuoles on Giemsa-stained smears) was investigated in 20 healthy control and 181 diseased dogs. In the group of the sick dogs 84 animals suffered from disorders affecting directly the haematological parameters or the haematopoietic organs such as bleeding, thymic haemorrhage, haemolytic disorders, lymphoma, immune-mediated thrombocytopenia, and other 97 dogs were affected by other diseases (hepatopathy, nephropathy, hepatic, splenic or intestinal neoplasm, skin diseases, diabetes mellitus, Cushing's syndrome, sepsis). The alterations found in platelet morphology were not specific for any disorder. The most common platelet abnormalities were polychromasia and the presence of giant platelets. These changes occurred in a high number in disorders accompanied by bleeding or haemolysis. Anisocytosis was the most frequent finding in hepatic, splenic or intestinal neoplasms and in certain endocrinopathies. Microcytosis was observed in immune-mediated thrombocytopenia, hepatic neoplasms and endocrine disorders. Extreme platelet activation was common in haemolysis, hepatopathies, neoplastic diseases and sepsis. Vacuolisation was present in thymic haemorrhage, pancreatitis, diabetes mellitus and Cushing's syndrome. A new morphologic phenomenon, i.e. a ring-like formation of granules, was described in the cytoplasm of the platelets both in healthy and diseased animals. In addition, two forms of pathologic granulation were also described for the first time in Giemsa-stained blood smears: the pseudonuclear and the spot-like formation of granules, which were observed especially in disorders affecting the blood cells. The granulation and morphological characteristics of platelets on smears stained by periodic acid-Schiff reaction (PAS) were also studied. Three localisations of granulation were observed, such as

  4. Severe Weather Guide - Mediterranean Ports - 24. Cartagena

    DTIC Science & Technology

    1988-08-01

    number) This handbook for the port of Cartagena, one in a series of severe weather guides for Mediterranean ports, provides decision-making guidance for... handbook is organized in four sections for ready reference: general guidance on handbook content and use; a quick-look captain’s summary; a more...34 R - 8 8 - RC (20) Un c lass i -f i ed rep or t DE (23) *PORTS, (FACILITIES), *1A|EA! HER, HANDBOOKS , HAZARDS, riED I 1 ::;;.;■ :H.:i:;;.HN EiEA

  5. An In-Port Feeding System for Shipboard Personnel. Volume 2. A Cost Benefit Analysis of the Use of Convenience Foods in a Military Foodservice Operation.

    DTIC Science & Technology

    1981-10-01

    proposed system was to provide highly acceptable and nutritious meals at a quality level that was equal to or better than that presently being served to...500-78#Fried Chicken 10 oz. 250-160# 500-320# Mashed Potatoes 24$1# Instant; 32$/1 gal 500-21#/16 gal 1000-42*/32 galGreen Peas 1/2 c. 250-50# 500-100

  6. Treatment of chronic subdural hematomas with subdural evacuating port system placement in the intensive care unit: evolution of practice and comparison with bur hole evacuation in the operating room.

    PubMed

    Flint, Alexander C; Chan, Sheila L; Rao, Vivek A; Efron, Allen D; Kalani, Maziyar A; Sheridan, William F

    2017-01-20

    OBJECTIVE The aims of this study were to evaluate a multiyear experience with subdural evacuating port system (SEPS) placement for chronic subdural hematoma (cSDH) in the intensive care unit at a tertiary neurosurgical center and to compare SEPS placement with bur hole evacuation in the operating room. METHODS All cases of cSDH evacuation were captured over a 7-year period at a tertiary neurosurgical center within an integrated health care delivery system. The authors compared the performance characteristics of SEPS and bur hole placement with respect to recurrence rates, change in recurrence rates over time, complications, length of stay, discharge disposition, and mortality rates. RESULTS A total of 371 SEPS cases and 659 bur hole cases were performed (n = 1030). The use of bedside SEPS placement for cSDH treatment increased over the 7-year period, from 14% to 80% of cases. Reoperation within 6 months was higher for the SEPS (15.6%) than for bur hole drainage (9.1%) across the full 7-year period (p = 0.002). This observed overall difference was due to a higher rate of reoperation during the same hospitalization (7.0% for SEPS vs 3.2% for bur hole; p = 0.008). Over time, as the SEPS procedure became more common and modifications of the SEPS technique were introduced, the rate of in-hospital reoperation after SEPS decreased to 3.3% (p = 0.02 for trend), and the difference between SEPS and bur hole recurrence was no longer significant (p = 0.70). Complications were uncommon and were similar between the groups. CONCLUSIONS Overall performance characteristics of bedside SEPS and bur hole drainage in the operating room were similar. Modifications to the SEPS technique over time were associated with a reduced reoperation rate.

  7. Visible and Infrared Optical Design for the ITER Upper Ports

    SciTech Connect

    Lasnier, C; Seppala, L; Morris, K; Groth, M; Fenstermacher, M; Allen, S; Synakowski, E; Ortiz, J

    2007-03-01

    This document contains the results of an optical design scoping study of visible-light and infrared optics for the ITER upper ports, performed by LLNL under contract for the US ITER Project Office. ITER is an international collaboration to build a large fusion energy tokamak with a goal of demonstrating net fusion power for pulses much longer than the energy confinement time. At the time of this report, six of the ITER upper ports are planned to each to contain a camera system for recording visible and infrared light, as well as other diagnostics. the performance specifications for the temporal and spatial resolution of this system are shown in the Section II, Functional Specifications. They acknowledge a debt to Y. Corre and co-authors of the CEA Cadarache report ''ITER wide-angle viewing and thermographic and visible system''. Several of the concepts used in this design are derived from that CEA report. The infrared spatial resolution for optics of this design is diffraction-limited by the size of the entrance aperture, at lower resolution than listed in the ITER diagnostic specifications. The size of the entrance aperture is a trade-off between spatial resolution, optics size in the port, and the location of relay optics. The signal-to-noise ratio allows operation at the specified time resolutions.

  8. Scenario analysis and disaster preparedness for port and maritime logistics risk management.

    PubMed

    Kwesi-Buor, John; Menachof, David A; Talas, Risto

    2016-08-01

    System Dynamics (SD) modelling is used to investigate the impacts of policy interventions on industry actors' preparedness to mitigate risks and to recover from disruptions along the maritime logistics and supply chain network. The model suggests a bi-directional relation between regulation and industry actors' behaviour towards Disaster Preparedness (DP) in maritime logistics networks. The model also showed that the level of DP is highly contingent on forecast accuracy, technology change, attitude to risk prevention, port activities, and port environment.

  9. An Information Requirements Analysis of Military Airlift Command (MAC) Aerial Port Operations.

    DTIC Science & Technology

    1987-09-01

    16:19 (January 1985). Office of Public Affairs. Military Airlift Command Aerial Ports. United States Air Force Fact Sheet. Scott AFB IL: August 1986...the author and do not necessarily reflect the views of the School of Systems and Logistics, the Air University, the United States Air Force, or the...intertheater ports are in the continental United States and are located at Travis AFB and Norton AFB, California; McChord AFB, Washington; McGuire AFB, New

  10. J-PAS and J-PLUS: large sky multi-filter surveys from the Observatorio Astrofisico de Javalambre

    NASA Astrophysics Data System (ADS)

    Cenarro, A. J.; J-PAS Collaboration; J-PLUS Collaboration

    2017-03-01

    During the first years of operation, the Observatorio Astrofísico de Javalambre, in Teruel, is mostly devoted to conduct two large sky multi-filter surveys making use of two telescopes of large field of view, JST/T250 and JAST/T80, and their respective panoramic instrumentation, JPCam and T80Cam. These surveys, managed and developed within a long-term Spanish-Brazilian collaboration of astronomers who cover most fields in Astronomy and Cosmology, are the Javalambre Physics of the Accelerating Universe Astrophysical Survey (J-PAS) and the Javalambre Photometric Local Universe Survey (J-PLUS). J-PAS will observe 8500 deg^2 of the sky visible from Javalambre with a set of 54 narrow-band contiguous optical filters plus 5 broader ones, performing in the end as a low resolution integral field unit for the Northern hemisphere. It will provide unprecedented spectral energy distributions for every pixel of the sky, and ultimately for more than 200 million galaxies and stars. In advance, J-PLUS has started to observe the same sky area of J-PAS with 12 narrow, intermediate and broad-band filters aimed to provide the photometric calibration of J-PAS, and unprecedented multicolor data for many fields of the Astrophysics. Both J-PAS and J-PLUS will provide powerful 3D views of the Universe that will be made publicly available to the community as legacy projects. This proceeding is aimed to present the origin, motivation, characteristics and main scientific goals of the J-PAS and J-PLUS projects as well as the Spanish-Brazilian collaboration making them happen.

  11. Protein Alpha Shape (PAS) Dock: A new gaussian-based score function suitable for docking in homology modelled protein structures

    NASA Astrophysics Data System (ADS)

    Tøndel, Kristin; Anderssen, Endre; Drabløs, Finn

    2006-03-01

    Protein Alpha Shape (PAS) Dock is a new empirical score function suitable for virtual library screening using homology modelled protein structures. Here, the score function is used in combination with the geometry search method Tabu search. A description of the protein binding site is generated using gaussian property fields like in Protein Alpha Shape Similarity Analysis (PASSA). Gaussian property fields are also used to describe the ligand properties. The overlap between the receptor and ligand hydrophilicity and lipophilicity fields is maximised, while minimising steric clashes. Gaussian functions introduce a smoothing of the property fields. This makes the score function robust against small structural variations, and therefore suitable for use with homology models. This also makes it less critical to include protein flexibility in the docking calculations. We use a fast and simplified version of the score function in the geometry search, while a more detailed version is used for the final prediction of the binding free energies. This use of a two-level scoring makes PAS-Dock computationally efficient, and well suited for virtual screening. The PAS-Dock score function is trained on 218 X-ray structures of protein- ligand complexes with experimental binding affinities. The performance of PAS-Dock is compared to two other docking methods, AutoDock and MOE-Dock, with respect to both accuracy and computational efficiency. According to this study, PAS-Dock is more computationally efficient than both AutoDock and MOE-Dock, and gives a better prediction of the free energies of binding. PAS-Dock is also more robust against structural variations than AutoDock.

  12. 4. View of houses from Port Ludlow, houses no. 69 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. View of houses from Port Ludlow, houses no. 69 and 70, facing southwest. House no. 69 in foreground, house no. 70 in background. - Houses Moved from Port Ludlow, Various Addresses (moved from Port Ludlow, WA), Port Gamble, Kitsap County, WA

  13. 77 FR 24656 - Extension of Port Limits of Indianapolis, IN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-25

    ... SECURITY U.S. Customs and Border Protection 19 CFR Part 101 Extension of Port Limits of Indianapolis, IN.... Customs and Border Protection (CBP) is proposing to extend the geographical limits of the port of entry of... limits of the Indianapolis, Indiana, port of entry. CBP ports of entry are locations where CBP...

  14. Medi-Port Pilot Randomized Controlled Trial

    ClinicalTrials.gov

    2016-10-13

    Actively Undergoing Cancer Treatment; 4-9 Years of Age; At Least 1 Month From Diagnosis; Able to Speak and Understand English; Presenting to Clinic for at Least a 2nd Subcutaneous Port Needle Insertion

  15. Rock Port Celebrates New Technology Center.

    ERIC Educational Resources Information Center

    Grones, Freda

    1997-01-01

    Discusses the advantages dome architecture gave to a new school technology center in Rock Port, Missouri. Advantages cover energy cost savings, lighting, storage space, aesthetics, accessibility, and convenience. (GR)

  16. Two-port circularly polarized microstrip antennas

    NASA Astrophysics Data System (ADS)

    Wang, B. F.

    A circularly polarized (CP) two-port microstrip antenna simultaneously operated at two CP states is investigated. The CP bandwidth of this antenna is increased by 0.35 percent to about 5 percent, almost 14 times wider than that of a single port patch. The antenna directivity due to the loss in the load is reduced by about 3 dB. Such a tradeoff should make the antenna much more useful for transmitting or receiving simultaneously two CP waves of opposite senses. The crosstalk between the two ports depends on the purity of the CP and is about -19 dB for axial ratios equal to 2 dB and -14 dB for axial ratio equal to 3 dB. A method for improving the isolation between the two antenna ports is discussed.

  17. Multi-port valve assembly

    DOEpatents

    Guggenheim, S. Frederic

    1986-01-01

    A multi-port fluid valve apparatus is used to control the flow of fluids through a plurality of valves and includes a web, which preferably is a stainless steel endless belt. The belt has an aperture therethrough and is progressed, under motor drive and control, so that its aperture is moved from one valve mechanism to another. Each of the valve mechanisms comprises a pair of valve blocks which are held in fluid-tight relationship against the belt. Each valve block consists of a block having a bore through which the fluid flows, a first seal surrounding the bore and a second seal surrounding the first seal, with the distance between the first and second seals being greater than the size of the belt aperture. In order to open a valve, the motor progresses the belt aperture to where it is aligned with the two bores of a pair of valve blocks, such alignment permitting a flow of the fluid through the valve. The valve is closed by movement of the belt aperture and its replacement, within the pair of valve blocks, by a solid portion of the belt.

  18. Severe Weather Guide, Mediterranean Ports. 18. Ibiza

    DTIC Science & Technology

    1988-05-01

    two piers (Figure 2-3). A fuel pier extends southwest from the northern side of the port, while Estacion Maritima pier extends northeastward from the...side of the port, while Estacion Maritima (Maritime Station) pier extends northeastward from the southern side. The westernmost basin is used...wind velocity. At a given wind speed and a given state of wave development, each spectrum has a band of frequencies where most of the total energy is

  19. Severe Weather Guide - Mediterranean Ports - 31. Taormina

    DTIC Science & Technology

    1989-06-01

    PORT SAID, EGYPT ANTALYA, TURKEY ISKENDERUN, TURKEY IZMIR , TURKEY GOLCUK, TURKEY ISTANBUL, TURKEY PORT ROTA, SPAIN TANGIER, MOROCCO ALGIERS...farther east. Holding in the anchorages is rated as good. However, the anchorages are on a rather steeply sloping bottom, so anchor dragging can...deep draft vessel. It is recommended that larger vessels anchor approximately 1,500 ft (457 m) farther east. Holding in the anchorages is rated as

  20. The Ability of PAS, Acetylsalicylic Acid and Calcium Disodium EDTA to Protect Against the Toxic Effects of Manganese on Mitochondrial Respiration in Gill of Crassostrea virginica

    PubMed Central

    Crawford, Sherine; Davis, Kiyya; Saddler, Claudette; Joseph, Jevaun; Catapane, Edward J.; Carroll, Margaret A.

    2011-01-01

    Manganese (Mn) is an essential metal that at excessive levels in brain causes Manganism, a condition similar to Parkinson's disease. Previously we showed that Mn had a neurotoxic effect on the dopaminergic, but not serotonergic, innervation of the lateral ciliated cells in the gill of the Eastern Oyster, Crassostrea virginica. While the mechanism of action of Mn toxicity is not completely understood, studies suggest that Mn toxicity may involve mitochondrial damage and resulting neural dysfunction in the brain’s dopaminergic system. In this study we utilized micro-batch chambers and oxygen probes to measure oyster gill mitochondrial respiration in the presence of Mn and potential Mn blockers. The addition of Mn to respiring mitochondria caused a dose dependent decrease in mitochondrial O2 consumption. Pretreating mitochondria with calcium disodium EDTA (caEDTA), p aminosalicylic acid (PAS) or acetylsalicylic acid (ASA) before Mn additions, provided full protection against the toxic effects of Mn. While mitochondrial pretreatment with any of the 3 drugs effectively blocked Mn toxicity, none of the drugs tested was able to reverse the decrease in mitochondrial O2 consumption seen in Mn treated mitochondria. The study found that high levels of Mn had a toxic effect on gill mitochondrial O2 consumption and that this effect could be blocked by the drugs caEDTA, PAS and ASA. C. virginica continues to be a good model with which to investigate the mechanism that underlies manganese neurotoxcity and in the pharmacological study of drugs to treat or prevent Manganism. PMID:21977482

  1. The PAS domain-containing histidine kinase RpfS is a second sensor for the diffusible signal factor of Xanthomonas campestris.

    PubMed

    An, Shi-Qi; Allan, John H; McCarthy, Yvonne; Febrer, Melanie; Dow, J Maxwell; Ryan, Robert P

    2014-05-01

    A cell-cell signalling system mediated by the fatty acid signal DSF controls the virulence of Xanthomonas campestris pv. campestris (Xcc) to plants. The synthesis and recognition of the DSF signal depends upon different Rpf proteins. DSF signal generation requires RpfF whereas signal perception and transduction depends upon the sensor RpfC and regulator RpfG. Detailed analyses of the regulatory roles of different Rpf proteins have suggested the occurrence of further sensors for DSF. Here we have used a mutagenesis approach coupled with high-resolution transcriptional analysis to identify XC_2579 (RpfS) as a second sensor for DSF in Xcc. RpfS is a complex sensor kinase predicted to have multiple Per/Arnt/Sim (PAS) domains, a histidine kinase domain and a C-terminal receiver (REC) domain. Isothermal calorimetry showed that DSF bound to the isolated N-terminal PAS domain with a Kd of 1.4 μM. RpfS controlled expression of a sub-set of genes distinct from those controlled by RpfC to include genes involved in type IV secretion and chemotaxis. Mutation of XC_2579 was associated with a reduction in virulence of Xcc to Chinese Radish when assayed by leaf spraying but not by leaf inoculation, suggesting a role for RpfS-controlled factors in the epiphytic phase of the disease cycle.

  2. Endeavor Approaches Docking Port of ISS

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Pictured here is the forward docking port on the International Space Station's (ISS) Destiny Laboratory as seen by one of the STS-111 crewmembers from the Space Shuttle Orbiter Endeavour just prior to docking. In June 2002, STS-111 provided the Space Station with a new crew, Expedition Five, replacing Expedition Four after remaining a record-setting 196 days in space. Three spacewalks enabled the STS-111 crew to accomplish additional mission objectives: the delivery and installation of a new platform for the ISS robotic arm, the Mobile Base System (MBS) which is an important part of the Station's Mobile Servicing System allowing the robotic arm to travel the length of the Station; the replacement of a wrist roll joint on the Station's robotic arm; and unloading supplies and science experiments form the Leonardo Multi-Purpose Logistics Module, which made its third trip to the orbital outpost. The STS-111 mission, the 14th Shuttle mission to visit the ISS, was launched on June 5, 2002 and landed June 19, 2002.

  3. Port-O-Sim Object Simulation Application

    NASA Technical Reports Server (NTRS)

    Lanzi, Raymond J.

    2009-01-01

    Port-O-Sim is a software application that supports engineering modeling and simulation of launch-range systems and subsystems, as well as the vehicles that operate on them. It is flexible, distributed, object-oriented, and realtime. A scripting language is used to configure an array of simulation objects and link them together. The script is contained in a text file, but executed and controlled using a graphical user interface. A set of modules is defined, each with input variables, output variables, and settings. These engineering models can be either linked to each other or run as standalone. The settings can be modified during execution. Since 2001, this application has been used for pre-mission failure mode training for many Range Safety Scenarios. It contains range asset link analysis, develops look-angle data, supports sky-screen site selection, drives GPS (Global Positioning System) and IMU (Inertial Measurement Unit) simulators, and can support conceptual design efforts for multiple flight programs with its capacity for rapid six-degrees-of-freedom model development. Due to the assembly of various object types into one application, the application is applicable across a wide variety of launch range problem domains.

  4. Management and prevention of complications of subcutaneous intravenous infusion port.

    PubMed

    Jan, Hsiang-Chun; Chou, Shao-Jiun; Chen, Tzu-Hung; Lee, Chuin-I; Chen, Tze-Kai; Lou, Mary Ann

    2012-03-01

    Subcutaneous intravenous infusion port (SIIP) has become an increasingly and widely adopted technique in the management of oncology patients. This route has been used not only for chemotherapy but also for parenteral nutrition provision, blood transfusion, medication administration, blood sample collection, hemodialysis, and so on. This system provides a safe vascular access with low complication rate which helps preventing patients from vascular infection and catheter associated thrombosis. In this study, we reviewed 1247 cases of breast cancer patients that had subcutaneous intravenous infusion port implanted for chemotherapy in our general surgery department from 1990 to 2008. The result indicates that complication decreases as our technique and experience mature. We hereby share our accrued experience and improved technique, hoping to be of help to young surgeons.

  5. Economic and geographic backgrounds of land reclamation in Japanese ports.

    PubMed

    Suzuki, Takeshi

    2003-01-01

    Under the present legal system, environmental impacts are usually assessed on condition that reclamation plans are given clearly. Although impact magnitude depends on reclamation scales, the economic and geographic backgrounds of reclamation scales have been rarely analyzed. Hence, properties of reclamation in port districts were investigated. The long-term trend showed that the area newly reclaimed per year has decreased rapidly since the first oil crisis; while the speed of the decrease dropped after 1984. The distributions of increased reclamation area planned against its water depth had one or two peaks in 1989-1991 and 1996-1998. These peaks resulted mainly from "island-type" reclamation, and shifted from shallow to deep sites. The areas of port districts had major effects on increased area of reclamation and maximum water depth in 1989-1991, while such effects were not observed in 1996-1998. Land price had some effects for deepening water depth of reclamation in both periods.

  6. Performance of the e2v 1.2 GPix cryogenic camera for the J-PAS 2.5m survey telescope

    NASA Astrophysics Data System (ADS)

    Robbins, M. S.; Bastable, M.; Bates, A.; Dryer, M.; Eames, S.; Fenemore-Jones, G.; Haddow, G.; Jorden, P. R.; Lane, B.; Marin-Franch, A.; Mortimer, J.; Palmer, I.; Puttay, N.; Renshaw, R.; Smith, M.; Taylor, K.; Tearle, J.; Weston, P.; Wheeler, P.; Worley, J.

    2016-08-01

    The J-PAS project will perform a five-year survey of the northern sky from a new 2.5m telescope in Teruel, Spain. In this paper the build and factory testing of the commercially supplied cryogenic camera is described. The 1.2 Giga-pixel focal plane is contained within a novel liquid-nitrogen cooled vacuum cryostat, which maintains the flatness for the cooled, 0.45m diameter focal plane to better than 27 μm peak to valley. The cooling system controls the focal plane to a temperature of -100°C with a variation across the focal plane of better than 2.5oC and a stability of better than +/- 0.5 °C over the long periods of operation required. The proximity drive electronics achieves total system level noise performance better than 5 e- from the 224-channel CCD system.

  7. Using Indium Tin Oxide To Mitigate Dust on Viewing Ports

    NASA Technical Reports Server (NTRS)

    2008-01-01

    NASA plans to use a number of onboard viewing ports to measure lunar regolith in situ and to monitor robotic and human activities on the lunar or Martian surface. Because of the size and abundance of dust particles on these bodies, the potential for dust to occlude viewing ports and windows is high enough to threaten system lifetime and reliability, especially when activities rely on relaying video to either a habitat module or controllers on Earth. This project uses a technology being developed by KSC's Electrostatics and Surface Physics Laboratory to remove dust from windowlike surfaces. The technology applies an alternating electric potential to interlaced electrodes. In this application, we use indium tin oxide (ITO) to create various electrode patterns in order to determine the most reliable pattern for dust removal. This technology has application to systems where optical clarity is important. Specifically, this project considers the in situ resource utilization (ISRU) application of a viewing port for Raman spectroscopy, where the electrode pattern on glass would be coated with a scratch-resistant sapphire film (Al2O3).

  8. Klonos: A Similarity Analysis Based Tool for Software Porting

    SciTech Connect

    and Oscar Hernandez, Wei Ding

    2014-07-30

    The Klonos is a compiler-based tool that can help users for scientific application porting. The tool is based on the similarity analysis with the help of the OpenUH compiler (a branch of Open64 compiler). This tool combines syntactic and cost-model-provided metrics clusters, which aggregate similar subroutines that can be ported similarity. The generated porting plan, which allows programmers and compilers to reuse porting experience as much as possible during the porting process.

  9. The Self Diagnosis Method. A new methodology to assess environmental management in sea ports.

    PubMed

    Darbra, R M; Ronza, A; Casal, J; Stojanovic, T A; Wooldridge, C

    2004-03-01

    A methodology has been designed to assess the performance of the environmental management in sea ports. The Self Diagnosis Method, developed by two research teams and about sixty sea ports, allows the comparison of the current environmental situation with that corresponding to previous years and the assessment of the opportunities for improvement. The main objective is to review the management activities and procedures that affect the environment and the way the port authority handles significant environmental aspects. It has been designed as a "first level" tool: it can be applied in approximately six hours by a non-expert user. It is based on the ISO 14001 vocabulary, requirements and structure, and it can be considered as a first step in the voluntary implementation of an environmental management system for port communities.

  10. [Comparison of port needle with safety device between Huber Plus (HP) and Poly PERF Safe (PPS)].

    PubMed

    Shimono, Chigusa; Tanaka, Atsuko; Fujita, Ai; Ishimoto, Miki; Oura, Shoji; Yamaue, Hiroki; Sato, Morio

    2010-05-01

    An embedded port is frequently used for outpatients with advanced cancer in central venous chemotherapy or hepatic arterial chemoinfusion. The port needle with a safety device in an ambulatory treatment center is indispensable for medical employees and patient plus family to reduce the risk of a needle puncture accident and to prevent iatrogenic infection. The port needle with safety system has been already introduced in our chemotherapy center. There are two types of port needle with safety device; Huber Plus (HP, Medicon Co., Ltd.) and POLY PERF Safe (PPS, Pyolax Device, Co., Ltd.). The comparison of the feasibility between HP and PPS was conducted by both medical employees and patients plus family using an inquiry score method. HP was highly regarded for its stability plus fixation and PPS for its usefulness in puncture and extraction of the needle. PPS was found to be preferable to HP based on the overall evaluation.

  11. Design and evaluation of candidate pressure ports for the HYFLITE experiment

    NASA Technical Reports Server (NTRS)

    Teter, John E., Jr.; Cleckner, Craig S.; Vontheumer, Alfred E.

    1994-01-01

    A concept for placing a pressure transducer directly in a shuttle type tile was developed at Langley Research Center. A 5 inch long quartz with a .020 inch inner diameter provides the thermal isolation necessary to allow 2800 F surface pressure measurements to be taken by pressure transducer rated at 250 F. The assembly is potted in place with RTV 560 in a piece of FRCI-12 thermal protection system insulation tile. The integrity of the thermal protection system is maintained even with the intrusion of the pressure port assembly and the pressure port does not disrupt the air flow across the lifting body. Approximately 200 of these pressure ports are to be used in each of the Hypersonic Flight Experiment (HYFLITE) flight tests. Initial vibroacoustic and aerothermal testing of the pressure port designs have been completed at Langley Research vibration laboratory and the 20 MWatt 2 x 9 turbulent duct facility at Ames Research Center. The performance of the pressure ports were found to be well within the required design limits for all cases. In addition, a failure mode in which the entire pressure port assembly was removed proved to be a begin case.

  12. Heavy-Duty Vehicle Port Drayage Drive Cycle Characterization and Development

    SciTech Connect

    Prohaska, Robert; Konan, Arnaud; Kelly, Kenneth; Lammert, Michael

    2016-10-06

    In an effort to better understand the operational requirements of port drayage vehicles and their potential for adoption of advanced technologies, National Renewable Energy Laboratory (NREL) researchers collected over 36,000 miles of in-use duty cycle data from 30 Class 8 drayage trucks operating at the Port of Long Beach and Port of Los Angeles in Southern California. These data include 1-Hz global positioning system location and SAE J1939 high-speed controller area network information. Researchers processed the data through NREL's Drive-Cycle Rapid Investigation, Visualization, and Evaluation tool to examine vehicle kinematic and dynamic patterns across the spectrum of operations. Using the k-medoids clustering method, a repeatable and quantitative process for multi-mode drive cycle segmentation, the analysis led to the creation of multiple drive cycles representing four distinct modes of operation that can be used independently or in combination. These drive cycles are statistically representative of real-world operation of port drayage vehicles. When combined with modeling and simulation tools, these representative test cycles allow advanced vehicle or systems developers to efficiently and accurately evaluate vehicle technology performance requirements to reduce cost and development time while ultimately leading to the commercialization of advanced technologies that meet the performance requirements of the port drayage vocation. The drive cycles, which are suitable for chassis dynamometer testing, were compared to several existing test cycles. This paper presents the clustering methodology, accompanying results of the port drayage duty cycle analysis and custom drive cycle creation.

  13. Heavy-Duty Vehicle Port Drayage Drive Cycle Characterization and Development: Preprint

    SciTech Connect

    Prohaska, Robert; Konan, Arnaud; Kelly, Kenneth; Lammert, Michael

    2016-08-01

    In an effort to better understand the operational requirements of port drayage vehicles and their potential for adoption of advanced technologies, National Renewable Energy Laboratory (NREL) researchers collected over 36,000 miles of in-use duty cycle data from 30 Class 8 drayage trucks operating at the Port of Long Beach and Port of Los Angeles in Southern California. These data include 1-Hz global positioning system location and SAE J1939 high-speed controller area network information. Researchers processed the data through NREL's Drive-Cycle Rapid Investigation, Visualization, and Evaluation tool to examine vehicle kinematic and dynamic patterns across the spectrum of operations. Using the k-medoids clustering method, a repeatable and quantitative process for multi-mode drive cycle segmentation, the analysis led to the creation of multiple drive cycles representing four distinct modes of operation that can be used independently or in combination. These drive cycles are statistically representative of real-world operation of port drayage vehicles. When combined with modeling and simulation tools, these representative test cycles allow advanced vehicle or systems developers to efficiently and accurately evaluate vehicle technology performance requirements to reduce cost and development time while ultimately leading to the commercialization of advanced technologies that meet the performance requirements of the port drayage vocation. The drive cycles, which are suitable for chassis dynamometer testing, were compared to several existing test cycles. This paper presents the clustering methodology, accompanying results of the port drayage duty cycle analysis and custom drive cycle creation.

  14. Immunosuppressive PAS-1 is an excretory/secretory protein released by larval and adult worms of the ascarid nematode Ascaris suum.

    PubMed

    Antunes, M F P; Titz, T O; Batista, I F C; Marques-Porto, R; Oliveira, C F; Alves de Araujo, C A; Macedo-Soares, M F

    2015-05-01

    Helminths use several strategies to evade and/or modify the host immune response, including suppression or inactivation of the host antigen-specific response. Several helminth immunomodulatory molecules have been identified. Our studies have focused on immunosuppression induced by the roundworm Ascaris suum and an A. suum-derived protein named protein 1 from A. suum (PAS-1). Here we assessed whether PAS-1 is an excretory/secretory (E/S) protein and whether it can suppress lipopolysaccharide-induced inflammation. Larvae from infective eggs were cultured in unsupplemented Dulbecco's modified Eagle medium (DMEM) for 2 weeks. PAS-1 was then measured in the culture supernatants and in adult A. suum body fluid at different time points by enzyme-linked immunosorbent assay (ELISA) with the monoclonal antibody MAIP-1. Secreted PAS-1 was detected in both larval culture supernatant and adult body fluid. It suppressed lipopolysaccharide (LPS)-induced leucocyte migration and pro-inflammatory cytokine production, and stimulated interleukin (IL)-10 secretion, indicating that larval and adult secreted PAS-1 suppresses inflammation in this model. Moreover, the anti-inflammatory activity of PAS-1 was abolished by treatment with MAIP-1, a PAS-1-specific monoclonal antibody, confirming the crucial role of PAS-1 in suppressing LPS-induced inflammation. These findings demonstrate that PAS-1 is an E/S protein with anti-inflammatory properties likely to be attributable to IL-10 production.

  15. Port side view of the Orbiter Discovery from an elevated ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Port side view of the Orbiter Discovery from an elevated platform in the Vehicle Assembly Building at NASA's Kennedy Space Center. Note the ground support hardware known as Strongbacks attached to the payload bay doors, the crew access hatch below the name Discovery on the forward section of the Orbiter and the removed Orbiter Maneuvering System/Reaction Control System pod from the aft (tai) section. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  16. Detail view of the aft section, port side, of the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of the aft section, port side, of the Orbiter Discovery from an elevated platform in the Vehicle Assembly Building at NASA's Kennedy Space Center. Note the removed Orbiter Maneuvering System/Reaction Control System pod from the base of the vertical stabilizer the strongback ground-support equipment attached to the payload bay door. This view is also a good view of the leading edge and top surface of the Orbiter wing. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  17. Multi-port, optically addressed RAM

    NASA Technical Reports Server (NTRS)

    Johnston, Alan R. (Inventor); Nixon, Robert H. (Inventor); Bergman, Larry A. (Inventor); Esener, Sadik (Inventor)

    1989-01-01

    A random access memory addressing system utilizing optical links between memory and the read/write logic circuits comprises addressing circuits including a plurality of light signal sources, a plurality of optical gates including optical detectors associated with the memory cells, and a holographic optical element adapted to reflect and direct the light signals to the desired memory cell locations. More particularly, it is a multi-port, binary computer memory for interfacing with a plurality of computers. There are a plurality of storage cells for containing bits of binary information, the storage cells being disposed at the intersections of a plurality of row conductors and a plurality of column conductors. There is interfacing logic for receiving information from the computers directing access to ones of the storage cells. There are first light sources associated with the interfacing logic for transmitting a first light beam with the access information modulated thereon. First light detectors are associated with the storage cells for receiving the first light beam, for generating an electrical signal containing the access information, and for conducting the electrical signal to the one of the storage cells to which it is directed. There are holographic optical elements for reflecting the first light beam from the first light sources to the first light detectors.

  18. 47 CFR Appendix B to Part 64 - Priority Access Service (PAS) for National Security and Emergency Preparedness (NSEP)

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... service (CMRS) networks. Under section 706 of the Communications Act, this authority may be superseded by... calls in progress and is to be used during situations when CMRS network congestion is blocking NSEP call... may direct service providers to remove PAS if appropriate. (Note: State and local government...

  19. 47 CFR Appendix B to Part 64 - Priority Access Service (PAS) for National Security and Emergency Preparedness (NSEP)

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Security and Emergency Preparedness (NSEP) B Appendix B to Part 64 Telecommunication FEDERAL COMMUNICATIONS.... 64, App. B Appendix B to Part 64—Priority Access Service (PAS) for National Security and Emergency... service (CMRS) networks. Under section 706 of the Communications Act, this authority may be superseded...

  20. 47 CFR Appendix B to Part 64 - Priority Access Service (PAS) for National Security and Emergency Preparedness (NSEP)

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Security and Emergency Preparedness (NSEP) B Appendix B to Part 64 Telecommunication FEDERAL COMMUNICATIONS.... 64, App. B Appendix B to Part 64—Priority Access Service (PAS) for National Security and Emergency... service (CMRS) networks. Under section 706 of the Communications Act, this authority may be superseded...

  1. 47 CFR Appendix B to Part 64 - Priority Access Service (PAS) for National Security and Emergency Preparedness (NSEP)

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Security and Emergency Preparedness (NSEP) B Appendix B to Part 64 Telecommunication FEDERAL COMMUNICATIONS.... 64, App. B Appendix B to Part 64—Priority Access Service (PAS) for National Security and Emergency... service (CMRS) networks. Under section 706 of the Communications Act, this authority may be superseded...

  2. 47 CFR Appendix B to Part 64 - Priority Access Service (PAS) for National Security and Emergency Preparedness (NSEP)

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Security and Emergency Preparedness (NSEP) B Appendix B to Part 64 Telecommunication FEDERAL COMMUNICATIONS.... 64, App. B Appendix B to Part 64—Priority Access Service (PAS) for National Security and Emergency... service (CMRS) networks. Under section 706 of the Communications Act, this authority may be superseded...

  3. Safety evaluation for packaging for the transport of K Basin sludge samples in the PAS-1 cask

    SciTech Connect

    SMITH, R.J.

    1998-11-17

    This safety evaluation for packaging authorizes the shipment of up to two 4-L sludge samples to and from the 325 Lab or 222-S Lab for characterization. The safety of this shipment is based on the current U.S. Department of Energy Certification of Compliance (CoC) for the PAS-1 cask, USA/9184/B(U) (DOE).

  4. The Psychiatric Assessment Schedule for Adult with Developmental Disability (PAS-ADD) Checklist: Reliability and Validity of French Version

    ERIC Educational Resources Information Center

    Gerber, F.; Carminati, G. Galli

    2013-01-01

    Background: The lack of psychometric measures of psychopathology especially in intellectual disabilities (ID) population was addressed by creation of the Psychiatric Assessment Schedule for Adult with Developmental Disability (PAS-ADD-10) in Moss et?al. This schedule is a structured interview designed for professionals in psychopathology. The…

  5. 76 FR 52269 - Safety Zone; Port Huron Float Down, St. Clair River, Port Huron, MI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-22

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Port Huron Float Down, St. Clair River... Port Huron Float Down. Though this is an unsanctioned, non-permitted event, this temporary safety zone... float-down events. DATES: This rule is effective and will be enforced from 12 to 8 p.m. on August...

  6. 78 FR 24069 - Safety Zone; 12th Annual Saltwater Classic; Port Canaveral Harbor; Port Canaveral, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-24

    ... traffic and the general public from traffic congestion associated with the tournament weigh-in. The safety... the fishing tournament, resulting in heavy vessel traffic within Port Canaveral Harbor. This event... vessel traffic within Port Canaveral Harbor. This safety zone extends approximately 1100 yards west...

  7. Spondylodiscite granulomateuse: surtout la tuberculose mais ne pas omettre le lymphome

    PubMed Central

    Zinebi, Ali; Rkiouak, Adil; Akhouad, Yousef; Reggad, Ahmed; Kasmy, Zohour; Boudlal, Mostafa; Lho, Abdelhamid Nait; Rabhi, Moncef; Sinaa, Mohamed; Ennibi, Khalid; Chaari, Jilali

    2016-01-01

    Les douleurs lombaires relèvent d'étiologies multiples dont le diagnostic peut être source de grandes difficultés. Le lymphome rachidien primitif est rare et son diagnostic nécessite une biopsie souvent scanoguidée. Un homme de 30 ans, était hospitalisé pour lombalgies inflammatoires évoluant dans un contexte d'altération de l'état général avec à l'examen des douleurs à la palpation des apophyses épineux L2L3, sans syndrome tumoral périphérique. Le bilan biologique montrait un syndrome inflammatoire. Le bilan morphologique était en faveur d'une spondylodiscite. La première biopsie montrait une ostéite granulomateuse. L'aggravation clinique et radiologique sous anti bacillaire a mené à reconsidérer le diagnostic et la deuxième biopsie confirme le diagnostic du lymphome. Le diagnostic de tuberculose osseuse en particulier vertébrale nécessite une confirmation bactériologique et ou histologique pour ne pas méconnaître un lymphome osseux primitif. PMID:28292061

  8. Location of an intermediate hub for port activities

    NASA Astrophysics Data System (ADS)

    Burciu, Ş.; Ştefănică, C.; Roşca, E.; Dragu, V.; Ruscă, F.

    2015-11-01

    An intermediate hub might increase the accessibility level of ports but also hinterland and so it can be considered more than a facility with a transhipment role. These hubs might lead to the development of other transport services and enhance their role in gathering and covering economic centres within hinterlands and also getting the part of logistic facility for the ports, with effects on port utilization and its connectivity to global economy. A new location for a hub terminal leads to reduced transport distances within hinterland, with decreased transport costs and external effects, so with gains in people's life quality. Because the production and distribution systems are relatively fixed on short and medium term and the location decisions are strategic and on long term, the logistic chains activities location models have to consider the uncertainties regarding the possible future situations. In most models, production costs are considered equal, the location problem reducing itself to a problem that aims to minimize the total transport costs, meaning the transport problem. The main objective of the paper is to locate a hub terminal that links the producers of cereals that are going to be exported by naval transportation with the Romanian fluvial-maritime ports (Galaţi, Brăila). GIS environment can be used to integrate and analyse a great amount of data and has the ability of using functions as location - allocation models necessary both to private and public sector, being able to determine the optimal location for services like factories, warehouses, logistic platforms and other public services.

  9. Chemiomics: Network Reconstruction and Kinetics of Port Wine Aging

    SciTech Connect

    Monforte, Ana Rita; Jacobson, Dan; Silva Ferreira, A. C.

    2015-02-11

    Network reconstruction (NR) has proven to be useful in the detection and visualization of relationships among the compounds present in a Port wine aging data set. This view of the data provides a considerable amount of information with which to understand the kinetic contexts of the molecules represented by peaks in each chromatogram. The aim of this paper was to use NR together with the determination of kinetic parameters to extract more information about the mechanisms involved in Port wine aging. The volatile compounds present in samples of Port wines spanning 128 years in age were measured with the use of GC-MS. After chromatogram alignment, a peak matrix was created, and all peak vectors were compared to one another to determine their Pearson correlations over time. A correlation network was created and filtered on the basis of the resulting correlation values. Some nodes in the network were further studied in experiments on Port wines stored under different conditions of oxygen and temperature in order to determine their kinetic parameters. The resulting network can be divided into three main branches. The first branch is related to compounds that do not directly correlate to age, the second branch contains compounds affected by temperature, and the third branch contains compounds associated with oxygen. Compounds clustered in the same branch of the network have similar expression patterns over time as well as the same kinetic order, thus are likely to be dependent on the same technological parameters. Network construction and visualization provides more information with which to understand the probable kinetic contexts of the molecules represented by peaks in each chromatogram. Finally, the approach described here is a powerful tool for the study of mechanisms and kinetics in complex systems and should aid in the understanding and monitoring of wine quality.

  10. Chemiomics: Network Reconstruction and Kinetics of Port Wine Aging

    DOE PAGES

    Monforte, Ana Rita; Jacobson, Dan; Silva Ferreira, A. C.

    2015-02-11

    Network reconstruction (NR) has proven to be useful in the detection and visualization of relationships among the compounds present in a Port wine aging data set. This view of the data provides a considerable amount of information with which to understand the kinetic contexts of the molecules represented by peaks in each chromatogram. The aim of this paper was to use NR together with the determination of kinetic parameters to extract more information about the mechanisms involved in Port wine aging. The volatile compounds present in samples of Port wines spanning 128 years in age were measured with the usemore » of GC-MS. After chromatogram alignment, a peak matrix was created, and all peak vectors were compared to one another to determine their Pearson correlations over time. A correlation network was created and filtered on the basis of the resulting correlation values. Some nodes in the network were further studied in experiments on Port wines stored under different conditions of oxygen and temperature in order to determine their kinetic parameters. The resulting network can be divided into three main branches. The first branch is related to compounds that do not directly correlate to age, the second branch contains compounds affected by temperature, and the third branch contains compounds associated with oxygen. Compounds clustered in the same branch of the network have similar expression patterns over time as well as the same kinetic order, thus are likely to be dependent on the same technological parameters. Network construction and visualization provides more information with which to understand the probable kinetic contexts of the molecules represented by peaks in each chromatogram. Finally, the approach described here is a powerful tool for the study of mechanisms and kinetics in complex systems and should aid in the understanding and monitoring of wine quality.« less

  11. An accurate cluster selection function for the J-PAS narrow-band wide-field survey

    NASA Astrophysics Data System (ADS)

    Ascaso, B.; Benítez, N.; Dupke, R.; Cypriano, E.; Lima-Neto, G.; López-Sanjuan, C.; Varela, J.; Alcaniz, J. S.; Broadhurst, T.; Cenarro, A. J.; Devi, N. Chandrachani; Díaz-García, L. A.; Fernandes, C. A. C.; Hernández-Monteagudo, C.; Mei, S.; Mendes de Oliveira, C.; Molino, A.; Oteo, I.; Schoenell, W.; Sodré, L.; Viironen, K.; Marín-Franch, A.

    2016-03-01

    The impending Javalambre Physics of the accelerating Universe Astrophysical Survey (J-PAS) will be the first wide-field survey of ≳ 8500 deg2 to reach the `stage IV' category. Because of the redshift resolution afforded by 54 narrow-band filters, J-PAS is particularly suitable for cluster detection in the range z<1. The photometric redshift dispersion is estimated to be only ˜0.003 with few outliers ≲4 per cent for galaxies brighter than i ˜ 23 AB, because of the sensitivity of narrow band imaging to absorption and emission lines. Here, we evaluate the cluster selection function for J-PAS using N-body+semi-analytical realistic mock catalogues. We optimally detect clusters from this simulation with the Bayesian Cluster Finder, and we assess the completeness and purity of cluster detection against the mock data. The minimum halo mass threshold we find for detections of galaxy clusters and groups with both >80 per cent completeness and purity is Mh ˜ 5 × 1013 M⊙ up to z ˜ 0.7. We also model the optical observable, M^{*}_CL-halo mass relation, finding a non-evolution with redshift and main scatter of σ _{M^{*}_CL | M_h}˜ 0.14 dex down to a factor 2 lower in mass than other planned broad-band stage IV surveys, at least. For the Mh ˜ 1 × 1014 M⊙ Planck mass limit, J-PAS will arrive up to z ˜ 0.85 with a σ _{M^{*}_CL | M_h}˜ 0.12 dex. Therefore, J-PAS will provide the largest sample of clusters and groups up to z ˜ 0.8 with a mass calibration accuracy comparable to X-ray data.

  12. Port Graham Community Building Biomass Heating Design Project

    SciTech Connect

    Norman, Patrick; Sink, Charles

    2015-04-30

    Native Village of Port Graham completed preconstruction activities to prepare for construction and operations of a cord wood biomass heating system to five or more community buildings in Port Graham, Alaska. Project Description Native Village of Port Graham (NVPG) completed preconstruction activities that pave the way towards reduced local energy costs through the construction and operations of a cord wood biomass heating system. NVPG plans include installation of a GARN WHS 3200 Boiler that uses cord wood as fuel source. Implementation of the 700,000 Btu per hour output biomass community building heat utility would heat 5-community buildings in Port Graham, Alaska. Heating system is estimated to displace 85% of the heating fuel oil or 5365 gallons of fuel on an annual basis with an estimated peak output of 600,000 Btu per hour. Estimated savings is $15,112.00 per year. The construction cost estimate made to install the new biomass boiler system is estimated $251,693.47 with an additional Boiler Building expansion cost estimated at $97,828.40. Total installed cost is estimated $349,521.87. The WHS 3200 Boiler would be placed inside a new structure at the old community Water Plant Building site that is controlled by NVPG. Design of the new biomass heat plant and hot water loop system was completed by Richmond Engineering, NVPG contractor for the project. A hot water heat loop system running off the boiler is designed to be placed underground on lands controlled by NVPG and stubbed to feed hot water to existing base board heating system in the following community buildings: 1. Anesia Anahonak Moonin Health and Dental Clinic 2. Native Village of Port Graham offices 3. Port Graham Public Safety Building/Fire Department 4. Port Graham Corporation Office Building which also houses the Port Graham Museum and Head Start Center 5. North Pacific Rim Housing Authority Workshop/Old Fire Hall Existing community buildings fuel oil heating systems are to be retro-fitted to

  13. Single-Port Parastomal Hernia Repair by Using 3-D Textile Implants

    PubMed Central

    Emmanuel, Klaus; Schrittwieser, Rudolf

    2014-01-01

    Background: Parastomal hernias (PSHs) are a frequent complication and remain a surgical challenge. We present a new option for single-port PSH repair with equilateral stoma relocation using preshaped, prosthetic 3-dimensional implants and flat mesh insertion in intraperitoneal onlay placement for additional augmentation of the abdominal wall. Methods: We describe our novel technique in detail and performed an analysis of prospectively collected data from patients who underwent single-port PSH repair, focusing on feasibility, conversions, and complications. Results: From September 2013 to January 2014, 9 patients with symptomatic PSHs were included. Two conversions to reduced-port laparoscopy using a second 3-mm trocar were required because of difficult adhesiolysis, dissection, and reduction of the hernia sac content. No major intra- or postoperative complications or reoperations were encountered. One patient incurred a peristomal wound healing defect that could be treated conservatively. Conclusion: We found that single-port PSH repair using preshaped, elastic 3-dimensional devices and additional flat mesh repair of the abdominal wall is feasible, safe, and beneficial, relating to optimal coverage of unstable stoma edges with wide overlap to all sides and simultaneous augmentation of the midline in the IPOM technique. The stoma relocation enables prolapse treatment and prevention. The features of a modular and rotatable multichannel port system offer benefits in clear dissection ongoing from a single port. Long-term follow-up data on an adequate number of patients are awaited to examine efficacy. PMID:25392655

  14. Transdermal power transfer for recharging implanted drug delivery devices via the refill port.

    PubMed

    Evans, Allan T; Chiravuri, Srinivas; Gianchandani, Yogesh B

    2010-04-01

    This paper describes a system for transferring power across a transdermal needle into a smart refill port for recharging implantable drug delivery systems. The device uses a modified 26 gauge (0.46 mm outer diameter) Huber needle with multiple conductive elements designed to couple with mechanical springs in the septum of the refill port of a drug delivery device to form an electrical connection that can sustain the current required to recharge a battery during a reservoir refill session. The needle is fabricated from stainless steel coated with Parylene, and the refill port septum is made from micromachined stainless steel contact springs and polydimethylsiloxane. The device properties were characterized with dry and wet ambient conditions. The needle and port pair had an average contact resistance of less than 2 Omega when mated in either environment. Electrical isolation between the system, the liquid in the needle lumen, and surrounding material has been demonstrated. The device was used to recharge a NiMH battery with currents up to 500 mA with less than 15 degrees C of resistive heating. The system was punctured 100 times to provide preliminary information with regard to device longevity, and exhibited about 1 Omega variation in contact resistance. The results suggest that this needle and refill port system can be used in an implant to enable battery recharging. This allows for smaller batteries to be used and ultimately increases the volume efficiency of an implantable drug delivery device.

  15. Detail view of the port side of the aft fuselage ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of the port side of the aft fuselage of the Orbiter Discovery in the transfer aisle of the Vehicle Assembly Building at Kennedy Space Center with a lifting frame attached to the aft attach points of the orbiter. In this view, the Orbiter Maneuvering/Reaction Control Systems pod is in place. Also note the darker-colored trapezoidal aft fuselage access door and the T-0 umbilical panel to its right in the view. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  16. Single incision laparoscopic splenectomy with double port.

    PubMed

    Vatansev, Celalettin; Ece, Ilhan

    2009-12-01

    In response to the increasing interest in minimally invasive surgery by both patients and surgeons, most abdominal surgery today is carried out laparoscopically. Laparoscopic splenectomy has become a gold standard in the treatment of spleen disorders related to hematologic diseases. Increasing laparoscopic surgery experience and improved new vessel sealing equipment have led to a decreasing number of ports in laparoscopic surgery and to operations from 1 incision. We carried out single-incision double-port laparoscopic splenectomy in a patient with immune thrombocytopenic purpura using only 2 trocars with a simple manipulation. Our review of the related literature revealed no earlier description of a single-incision double-port laparoscopic splenectomy. We therefore present herein this earlier unreported technique.

  17. Prevalence of psychoactive substances in truck drivers in the Nord-Pas-de-Calais region (France).

    PubMed

    Labat, Laurence; Fontaine, Bernard; Delzenne, Chantal; Doublet, Anne; Marek, Marie Christine; Tellier, Dominique; Tonneau, Murielle; Lhermitte, Michel; Frimat, Paul

    2008-01-30

    A previous study conducted in 1995 showed that psychoactive drug use by workers was higher in safety/security workstations than in the rest of the labour force. In order to verify this finding, we conducted a new study in 2003-2004 in the Nord-Pas-de-Calais region, restricted to truck drivers. The aim of this study was to allow harmonizing the professional practice of the occupational physicians, proposing drug prevention and drug testing policies, validating the analytical methods and the guidelines in case of positive testing results. One thousand truck drivers were studied. Urines were tested for amphetamines, cannabinoids, cocaine, opiates, benzodiazepines, buprenorphine and methadone by immunoassay. Urine ethanol determinations were performed by an ADH method. Positive urines for drugs of abuse, methadone or buprenorphine were then tested by gas chromatography or liquid chromatography coupled to mass spectrometry. Out of the 1000 drivers, cannabinoids were detected in 85 cases, opiates in 41 cases, amphetamines in 3 cases and cocaine in only one case. Buprenorphine was detected in 18 cases, methadone in 5 cases and benzodiazepines in 4 cases. Urine ethanol was positive in 50 cases. We found only one case with 6-monoacetylmorphine. Other positive opiates were metabolites of antitussives. The relatively low number of benzodiazepine positive urines could be explained by the lack of sensitivity of the test we used. All these results confirm those of the previous study for cannabinoids and ethanol in safety/security workstations. Positive results for methadone and buprenorphine are eight times higher than in the general population. In conclusion, the authors think that it will be of a great interest to test urine of truck drivers for other classes of psychoactive drugs, using a liquid chromatography-mass spectrometry method.

  18. Integration of remote sensing (RS) and geographic information system (GIS) techniques for change detection of the land use and land cover (LULC) for soil management in the southern Port Said region, Egypt

    NASA Astrophysics Data System (ADS)

    Hassan, Mohamed Abd El Rehim Abd El Aziz

    2014-11-01

    The monitoring of land use/land cover (LULC) changes in southern Port Said region area is very important for the planner of managements, governmental and non-governmental organizations, decision makers and the scientific community. This information is essential for planning and implementing policies to optimize the use of natural resources and accommodate development whilst minimizing the impact on the environment. To monitor these changes in the study area, two sets of satellite images (Landsat TM-5 and ETM+7) data were used with Path/Row (175/38) in date 1986 and 2006, respectively. The Landsat TM and ETM data are useful for this type of study due to its high spatial resolution, spectral resolution and low repetitive acquisition (16 days). A postclassification technique is used in this study based on hybrid classification (Unsupervised and Supervised). Each method used was assessed, and checked in field. Eight to Twelve LULC classes are recognized and mapping produced. The soils in southern Port Said area were classification in two orders for soil taxonomic units, which are Entisols and Aridisols and four sub-orders classes. The study land was evaluated into five classes from non suitable (N) to very highly suitable (S1) for some crops in the southern region of Port Said studied soils, with assess the nature of future change following construction of the international coastal road which crosses near to the study area.

  19. Severe Weather Guide, Mediterranean Ports. 16. Barcelona

    DTIC Science & Technology

    1988-05-01

    and Besos rivers at 41»22’N 002»11’E (Figure 2-2). Figure 2-2. Region of the Port of Barcelona. 2-2 The Port of Barcelona is capable of...Llobregat and Besos rivers at 41൞’N 002»11’E (Figure 3-2). NAUTICAL MILE SCALE -^ It >■ 0 , UobngatR. ’BARCELONA Bhro f^: GULF OF VALENCIA...OOCUMENTATION 2. AVENUE RAPP 75340 PARIS CEDEX 07 FRANCE SERVICE HYDROGRAPHIQUE ET OCEANOGRAPHIQUE DE LA MARINE ESTABLISSEMENT PRINCIPAL RUE OU

  20. Laser treatment of port-wine stains

    PubMed Central

    Brightman, Lori A; Geronemus, Roy G; Reddy, Kavitha K

    2015-01-01

    Port-wine stains are a type of capillary malformation affecting 0.3% to 0.5% of the population. Port-wine stains present at birth as pink to erythematous patches on the skin and/or mucosa. Without treatment, the patches typically darken with age and may eventually develop nodular thickening or associated pyogenic granuloma. Laser and light treatments provide improvement through selective destruction of vasculature. A variety of vascular-selective lasers may be employed, with the pulsed dye laser being the most common and well studied. Early treatment produces more optimal results. Advances in imaging and laser treatment technologies demonstrate potential to further improve clinical outcomes. PMID:25624768

  1. Advanced uncertainty modelling for container port risk analysis.

    PubMed

    Alyami, Hani; Yang, Zaili; Riahi, Ramin; Bonsall, Stephen; Wang, Jin

    2016-08-13

    Globalization has led to a rapid increase of container movements in seaports. Risks in seaports need to be appropriately addressed to ensure economic wealth, operational efficiency, and personnel safety. As a result, the safety performance of a Container Terminal Operational System (CTOS) plays a growing role in improving the efficiency of international trade. This paper proposes a novel method to facilitate the application of Failure Mode and Effects Analysis (FMEA) in assessing the safety performance of CTOS. The new approach is developed through incorporating a Fuzzy Rule-Based Bayesian Network (FRBN) with Evidential Reasoning (ER) in a complementary manner. The former provides a realistic and flexible method to describe input failure information for risk estimates of individual hazardous events (HEs) at the bottom level of a risk analysis hierarchy. The latter is used to aggregate HEs safety estimates collectively, allowing dynamic risk-based decision support in CTOS from a systematic perspective. The novel feature of the proposed method, compared to those in traditional port risk analysis lies in a dynamic model capable of dealing with continually changing operational conditions in ports. More importantly, a new sensitivity analysis method is developed and carried out to rank the HEs by taking into account their specific risk estimations (locally) and their Risk Influence (RI) to a port's safety system (globally). Due to its generality, the new approach can be tailored for a wide range of applications in different safety and reliability engineering and management systems, particularly when real time risk ranking is required to measure, predict, and improve the associated system safety performance.

  2. Single-port robotic cholecystectomy. Initial and pioneer experience in Brazil

    PubMed Central

    Schraibman, Vladimir; Epstein, Marina Gabrielle; Maccapani, Gabriel Naman; Macedo, Antônio Luiz de Vasconcellos

    2015-01-01

    The technique of a single-port laparoscopy was developed over the last years as an attempt to lower surgical aggression and improve the aesthetic results of the minimally invasive surgery. A new robotic platform used with the da Vinci® Robotic System Single-Site System® (Intuitive Surgical, Sunnyvale, California, United States) was recently launched on the global market and is still not documented in Brazil. The authors report on the first four robotic single-port cholecystectomies performed with this da Vinci® Robotic System in Brazil. PMID:26398360

  3. Radiation and Shipping Port Security | RadTown USA | US ...

    EPA Pesticide Factsheets

    2016-02-23

    Cargo comes into the U.S. from all over the world. Ports can ensure safety by: Screening cargo for radiation before it gets here. Safely handling any radioactive material that needs to pass through a port.

  4. 9 CFR 93.703 - Ports designated for importation.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Springs, VT; Oroville and Sumas, WA. (3) Mexican border ports. Douglas, Naco, Nogales, Sasabe, and San... Houston, TX; and Seattle, Spokane, and Tacoma, WA. (2) Canadian border ports. Eastport, ID; Houlton...

  5. 9 CFR 93.703 - Ports designated for importation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Springs, VT; Oroville and Sumas, WA. (3) Mexican border ports. Douglas, Naco, Nogales, Sasabe, and San... Houston, TX; and Seattle, Spokane, and Tacoma, WA. (2) Canadian border ports. Eastport, ID; Houlton...

  6. Port wine stain on a child's face (image)

    MedlinePlus

    Port wine stains are always present at birth. In an infant, they are flat, pink, vascular lesions. Common locations ... may be present anywhere on the body. Port wine stains may appear in association with other syndromes.

  7. 7 CFR 322.27 - Eligible ports for transit shipments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... of Restricted Organisms Through the United States § 322.27 Eligible ports for transit shipments. You may transit restricted organisms only through a port of entry staffed by an APHIS inspector. 7 7...

  8. Dynamic particle accumulation structure (PAS) in half-zone liquid bridge Reconstruction of particle motion by 3-D PTV

    NASA Astrophysics Data System (ADS)

    Ueno, I.; Abe, Y.; Noguchi, K.; Kawamura, H.

    Three-dimensional (3-D) velocity field reconstruction of oscillatory thermocapillary convections in a half-zone liquid bridge with a radius of O (1 mm) was carried out by applying 3-D particle tracking velocimetry (PTV). Simultaneous observation of the particles suspended in the bridge by two CCD cameras was carried out by placing a small cubic beam splitter above a transparent top rod. The reconstruction of the 3-D trajectories and the velocity fields of the particles in the several types of oscillatory-flow regimes were conducted successfully for sufficiently long period without losing particle tracking. With this application the present authors conducted a series of experiments focusing upon the collapse and re-formation process of the PAS by mechanically disturbing fully developed PAS.

  9. 76 FR 36318 - Safety Zone; Waterway Closure, Morgan City-Port Allen Route From Mile Marker 0 to Port Allen Lock

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-22

    ... and tows from destruction, loss or injury due to hazards associated with rising flood water. DATES... the general public, levee system, vessels and tows from the hazards associated with rising flood water... hazards associated with rising flood water on the Morgan City-Port Allen Route. Basis and Purpose...

  10. Television as Textbook: "Cuéntame cómo pasó" in the Spanish (Literature) Classroom

    ERIC Educational Resources Information Center

    Bartlett, Linda; Manyé, Lourdes

    2015-01-01

    The long-running Spanish television program "Cuéntame cómo pasó" represents not only a wildly successful series for Radio Televisión Española, but also an excellent example of the project of historical memory. Premiering in 2001 (but set, in the first season, in 1968), the story of the multigenerational Alcántara family forms a…

  11. Ports Primer: 7.3 Federal Environmental Regulations, Initiatives and Standards

    EPA Pesticide Factsheets

    Near-port communities are often disproportionately impacted by air emissions due to port operations, goods movement operations and other industries that may be co-located with ports. Air emissions at ports also impact regional air quality.

  12. Velopharyngeal Port Status during Classical Singing

    ERIC Educational Resources Information Center

    Tanner, Kristine; Roy, Nelson; Merrill, Ray M.; Power, David

    2005-01-01

    Purpose: This investigation was undertaken to examine the status of the velopharyngeal (VP) port during classical singing. Method: Using aeromechanical instrumentation, nasal airflow (mL/s), oral pressure (cm H[subscript 2]O), and VP orifice area estimates (cm[squared]) were studied in 10 classically trained sopranos during singing and speaking.…

  13. 33 CFR 165.761 - Security Zones; Port of Palm Beach, Port Everglades, Port of Miami, and Port of Key West, Florida.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... all waters between Watson Park and Star Island on the MacArthur Causeway south to the Port of Miami...′ N, 080°10.92′ W to 25°46.88′ N, 080°10.84′ W, and ending on Watson Park at 25°47.00′ N, 080°10.67′...

  14. 33 CFR 165.761 - Security Zones; Port of Palm Beach, Port Everglades, Port of Miami, and Port of Key West, Florida.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... of the law enforcement boats and cruise ship tenders which will mark a transit lane in channel. (ii... east of the law enforcement vessels and cruise ship tenders, which will mark a transit lane in the... Port Miami or his designated representative. Other vessels such as pilot boats, cruise ship...

  15. 33 CFR 165.761 - Security Zones; Port of Palm Beach, Port Everglades, Port of Miami, and Port of Key West, Florida.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... all waters between Watson Park and Star Island on the MacArthur Causeway south to the Port of Miami... approximate position 25°46.33′ N, 080°09.12′ W, which leads to Star Island, and MacArthur Causeway...

  16. 33 CFR 165.761 - Security Zones; Port of Palm Beach, Port Everglades, Port of Miami, and Port of Key West, Florida.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... all waters between Watson Park and Star Island on the MacArthur Causeway south to the Port of Miami... approximate position 25°46.33′ N, 080°09.12′ W, which leads to Star Island, and MacArthur Causeway...

  17. 46 CFR 171.116 - Port lights.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Port lights. 171.116 Section 171.116 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SUBDIVISION AND STABILITY SPECIAL RULES PERTAINING TO VESSELS CARRYING PASSENGERS Openings in the Side of a Vessel Below the Bulkhead or Weather Deck §...

  18. 46 CFR 171.116 - Port lights.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Port lights. 171.116 Section 171.116 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SUBDIVISION AND STABILITY SPECIAL RULES PERTAINING TO VESSELS CARRYING PASSENGERS Openings in the Side of a Vessel Below the Bulkhead or Weather Deck §...

  19. 46 CFR 171.116 - Port lights.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Port lights. 171.116 Section 171.116 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SUBDIVISION AND STABILITY SPECIAL RULES PERTAINING TO VESSELS CARRYING PASSENGERS Openings in the Side of a Vessel Below the Bulkhead or Weather Deck §...

  20. 50 CFR 14.16 - Border ports.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 1 2014-10-01 2014-10-01 false Border ports. 14.16 Section 14.16 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR TAKING, POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS...

  1. 50 CFR 14.16 - Border ports.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 1 2010-10-01 2010-10-01 false Border ports. 14.16 Section 14.16 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR TAKING, POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS...

  2. 50 CFR 14.16 - Border ports.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 1 2012-10-01 2012-10-01 false Border ports. 14.16 Section 14.16 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR TAKING, POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS...

  3. 50 CFR 14.16 - Border ports.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 1 2011-10-01 2011-10-01 false Border ports. 14.16 Section 14.16 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR TAKING, POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS...

  4. 50 CFR 14.16 - Border ports.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 1 2013-10-01 2013-10-01 false Border ports. 14.16 Section 14.16 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR TAKING, POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS...

  5. Hardening communication ports for survival in electrical overstress environments

    NASA Technical Reports Server (NTRS)

    Clark, O. Melville

    1991-01-01

    Greater attention is being focused on the protection of data I/O ports since both experience and lab tests have shown that components at these locations are extremely vulnerable to electrical overstress (EOS) in the form of transient voltages. Lightning and electrostatic discharge (ESD) are the major contributors to these failures; however, these losses can be prevented. Hardening against transient voltages at both the board level and system level has a proven record of improving reliability by orders of magnitude. The EOS threats, typical failure modes, and transient voltage mitigation techniques are reviewed. Case histories are also reviewed.

  6. Early doors (Edo) mutant mouse reveals the importance of period 2 (PER2) PAS domain structure for circadian pacemaking

    PubMed Central

    Militi, Stefania; Maywood, Elizabeth S.; Sandate, Colby R.; Chesham, Johanna E.; Parsons, Michael J.; Vibert, Jennifer L.; Joynson, Greg M.; Partch, Carrie L.; Hastings, Michael H.; Nolan, Patrick M.

    2016-01-01

    The suprachiasmatic nucleus (SCN) defines 24 h of time via a transcriptional/posttranslational feedback loop in which transactivation of Per (period) and Cry (cryptochrome) genes by BMAL1–CLOCK complexes is suppressed by PER–CRY complexes. The molecular/structural basis of how circadian protein complexes function is poorly understood. We describe a novel N-ethyl-N-nitrosourea (ENU)-induced mutation, early doors (Edo), in the PER-ARNT-SIM (PAS) domain dimerization region of period 2 (PER2) (I324N) that accelerates the circadian clock of Per2Edo/Edo mice by 1.5 h. Structural and biophysical analyses revealed that Edo alters the packing of the highly conserved interdomain linker of the PER2 PAS core such that, although PER2Edo complexes with clock proteins, its vulnerability to degradation mediated by casein kinase 1ε (CSNK1E) is increased. The functional relevance of this mutation is revealed by the ultrashort (<19 h) but robust circadian rhythms in Per2Edo/Edo; Csnk1eTau/Tau mice and the SCN. These periods are unprecedented in mice. Thus, Per2Edo reveals a direct causal link between the molecular structure of the PER2 PAS core and the pace of SCN circadian timekeeping. PMID:26903623

  7. DAC-3 Pointing Stability Analysis Results for SAGE 3 and Other Users of the International Space Station (ISS) Payload Attachment Sites (PAS)

    NASA Technical Reports Server (NTRS)

    Woods-Vedeler, Jessica A.; Rombado, Gabriel

    1997-01-01

    The purpose of this paper is to provide final results of a pointing stability analysis for external payload attachment sites (PAS) on the International Space Station (ISS). As a specific example, the pointing stability requirement of the SAGE III atmospheric science instrument was examined in this paper. The instrument requires 10 arcsec stability over 2 second periods. SAGE 3 will be mounted on the ISS starboard side at the lower, outboard FIAS. In this engineering analysis, an open-loop DAC-3 finite element model of ISS was used by the Microgravity Group at Johnson Space Flight Center to generate transient responses at PAS to a limited number of disturbances. The model included dynamics up to 50 Hz. Disturbance models considered included operation of the solar array rotary joints, thermal radiator rotary joints, and control moment gyros. Responses were filtered to model the anticipated vibration attenuation effects of active control systems on the solar and thermal radiator rotary joints. A pointing stability analysis was conducted by double integrating acceleration transient over a 2 second period. Results of the analysis are tabulated for ISS X, Y, and Z Axis rotations. These results indicate that the largest excursions in rotation during pointing occurred due to rapid slewing of the thermal radiator. Even without attenuation at the rotary joints, the resulting pointing error was limited to less than 1.6 arcsec. With vibration control at the joints, to a maximum 0.5 arcsec over a 2 second period. Based on this current level of model definition, it was concluded that between 0 - 50 Hz, the pointing stability requirement for SAGE 3 will not be exceeded by the disturbances evaluated in this study.

  8. Accurate PSF-matched photometry for the J-PAS survey

    NASA Astrophysics Data System (ADS)

    Jimenez-Teja, Yolanda; Benitez, Txitxo; Dupke, Renato a.

    2015-08-01

    The Javalambre-PAU Astrophysical Survey (J-PAS) is expected to map 8,600 squared-degrees of the sky using 54 narrow and 5 broad band filters. Carried out by a Spanish-Brazilian consortium, the main goal of this survey is to measure Baryon Acoustic Oscillations (BAOs) with photometric redshifts. The expectation is measuring these photometric redshifts with a precision of dz/(1 + z) ~ 0.003 for 100 million galaxies and a few millions of quasars, and reaching an accuracy of dz/(1 + z) ~ 0.01 for other 300 million galaxies. With these numbers, it will be possible to determine w in the Dark Energy (DE) equation of state with an accuracy of < 4%. To achieve such precision and measure the radial BAOs, not only an advanced technical setup but also special data processing tools are required. These tools must be accurate as well as suitable to be implemented in fully automated and computationally efficient algorithms.The factor that most influences the photometric redshift precision is the quality of the photometry. For that reason we have developed a new technique based on the Chebyshev-Fourier bases (CHEFs, Jiménez-Teja & Benítez 2012, ApJ, 745, 150) to obtain a highly precise multicolor photometry without PSF consideration, thus saving a considerable amount of time and circumventing severe problems such as the PSF variability across the images. The CHEFs are a set of mathematical orthonormal bases with different scale and resolution levels, originally designed to fit the surface light distribution of galaxies. They have proved to be able to model any kind of morphology, including spirals, highly elliptical, or irregular galaxies, including isophotal twists and fine substructure. They also fit high signal-to-noise images, lensing arcs and stars with great accuracy. We can calculate optimal, unbiased, total magnitudes directly through these CHEFs models and, thus, colors without needing the PSF.We compare our photometry with widely-used codes such as SExtractor (Bertin

  9. 46 CFR Sec. 3 - Federal control of port facilities.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 8 2012-10-01 2012-10-01 false Federal control of port facilities. Sec. 3 Section 3 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION B-CONTROL AND UTILIZATION OF PORTS... Federal control of port facilities. During any period when the provisions of this part are in effect...

  10. 33 CFR 6.01-3 - Captain of the Port.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Captain of the Port. 6.01-3... PROTECTION AND SECURITY OF VESSELS, HARBORS, AND WATERFRONT FACILITIES Definitions § 6.01-3 Captain of the Port. Captain of the Port as used in this part, means the officer of the Coast Guard, under the...

  11. 33 CFR 1.01-30 - Captains of the Port.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Captains of the Port. 1.01-30 Section 1.01-30 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY GENERAL GENERAL PROVISIONS Delegation of Authority § 1.01-30 Captains of the Port. Captains of the Port and...

  12. 33 CFR 125.05 - Captain of the Port.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Captain of the Port. 125.05 Section 125.05 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED... VESSELS § 125.05 Captain of the Port. The term Captain of the Port means the officer of the Coast...

  13. 33 CFR 6.01-3 - Captain of the Port.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Captain of the Port. 6.01-3... PROTECTION AND SECURITY OF VESSELS, HARBORS, AND WATERFRONT FACILITIES Definitions § 6.01-3 Captain of the Port. Captain of the Port as used in this part, means the officer of the Coast Guard, under the...

  14. 75 FR 3859 - Safety Zone; Baltimore Captain of Port Zone

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-25

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Baltimore Captain of Port Zone AGENCY... establishing a temporary safety zone in all navigable waters of the Captain of the Port Baltimore zone. The... authorized by the Captain of the Port Baltimore, or his designated representative. This safety zone...

  15. 33 CFR 125.05 - Captain of the Port.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Captain of the Port. 125.05 Section 125.05 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED... VESSELS § 125.05 Captain of the Port. The term Captain of the Port means the officer of the Coast...

  16. 33 CFR 1.01-30 - Captains of the Port.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Captains of the Port. 1.01-30 Section 1.01-30 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY GENERAL GENERAL PROVISIONS Delegation of Authority § 1.01-30 Captains of the Port. Captains of the Port and...

  17. 33 CFR 6.01-3 - Captain of the Port.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Captain of the Port. 6.01-3... PROTECTION AND SECURITY OF VESSELS, HARBORS, AND WATERFRONT FACILITIES Definitions § 6.01-3 Captain of the Port. Captain of the Port as used in this part, means the officer of the Coast Guard, under the...

  18. 33 CFR 6.01-3 - Captain of the Port.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Captain of the Port. 6.01-3... PROTECTION AND SECURITY OF VESSELS, HARBORS, AND WATERFRONT FACILITIES Definitions § 6.01-3 Captain of the Port. Captain of the Port as used in this part, means the officer of the Coast Guard, under the...

  19. 33 CFR 1.01-30 - Captains of the Port.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Captains of the Port. 1.01-30 Section 1.01-30 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY GENERAL GENERAL PROVISIONS Delegation of Authority § 1.01-30 Captains of the Port. Captains of the Port and...

  20. 33 CFR 125.05 - Captain of the Port.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Captain of the Port. 125.05 Section 125.05 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED... VESSELS § 125.05 Captain of the Port. The term Captain of the Port means the officer of the Coast...

  1. 78 FR 19161 - Security Zones; Captain of the Port Detroit

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-29

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA87 Security Zones; Captain of the Port Detroit AGENCY... permanent security zone within the Captain of the Port Detroit Zone. This proposed security zone is intended... event will likely recur annually, the Captain of the Port Detroit is proposing to establish a...

  2. 33 CFR 125.05 - Captain of the Port.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Captain of the Port. 125.05 Section 125.05 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED... VESSELS § 125.05 Captain of the Port. The term Captain of the Port means the officer of the Coast...

  3. 33 CFR 6.01-3 - Captain of the Port.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Captain of the Port. 6.01-3... PROTECTION AND SECURITY OF VESSELS, HARBORS, AND WATERFRONT FACILITIES Definitions § 6.01-3 Captain of the Port. Captain of the Port as used in this part, means the officer of the Coast Guard, under the...

  4. 33 CFR 1.01-30 - Captains of the Port.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Captains of the Port. 1.01-30 Section 1.01-30 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY GENERAL GENERAL PROVISIONS Delegation of Authority § 1.01-30 Captains of the Port. Captains of the Port and...

  5. 33 CFR 125.05 - Captain of the Port.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Captain of the Port. 125.05 Section 125.05 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED... VESSELS § 125.05 Captain of the Port. The term Captain of the Port means the officer of the Coast...

  6. 33 CFR 1.01-30 - Captains of the Port.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Captains of the Port. 1.01-30 Section 1.01-30 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY GENERAL GENERAL PROVISIONS Delegation of Authority § 1.01-30 Captains of the Port. Captains of the Port and...

  7. The Port of Baltimore Workplace Skills Development Project. Performance Report.

    ERIC Educational Resources Information Center

    Amarantides, Niki; Blumner, Ellen

    The Port of Baltimore Workplace Skills Development Project had the following objectives: perform literacy audits on at least 20 job titles within the port-related industries; develop curriculum modules providing literacy skill instruction using a functional context approach reflecting the Port of Baltimore needs; offer instructional services to at…

  8. 75 FR 51243 - Trade Mission to the Port of Veracruz

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-19

    ... Mexico City area important to ports infrastructure development at the national level. Participants will.... --Lunch with Veracruz industry leaders. --Networking reception with industry contacts. --Breakfast with... December 7--Mexico City-Port of Veracruz Breakfast on their own Trip to the Port of Veracruz Lunch...

  9. 1. General view of complex, showing main port building at ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. General view of complex, showing main port building at right background. View to northwest. - U.S. Customs Service Port of Roosville, Main Port Building, U.S. Highway 93, immediately south of U.S.-Canadian border, Eureka, Lincoln County, MT

  10. 46 CFR Sec. 4 - Port facilities predesignated for emergency use.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false Port facilities predesignated for emergency use. Sec. 4... FACILITIES Sec. 4 Port facilities predesignated for emergency use. (a) Certain port facilities selected for...) Facilities which are not required by the United States immediately on the effective date of this part will...

  11. 46 CFR Sec. 3 - Federal control of port facilities.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false Federal control of port facilities. Sec. 3 Section 3... RESTRICTIONS UPON THE TRANSFER OR CHANGE IN USE OR IN TERMS GOVERNING UTILIZATION OF PORT FACILITIES Sec. 3 Federal control of port facilities. During any period when the provisions of this part are in effect...

  12. 46 CFR 340.6 - Port facilities and services.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false Port facilities and services. 340.6 Section 340.6... AND ALLOCATION OF SHIPPING SERVICES, CONTAINERS AND CHASSIS, AND PORT FACILITIES AND SERVICES FOR NATIONAL SECURITY AND NATIONAL DEFENSE RELATED OPERATIONS § 340.6 Port facilities and services. (a) When...

  13. 78 FR 54755 - Extension of Port Limits of Indianapolis, IN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-06

    ... SECURITY U.S. Customs and Border Protection 19 CFR Part 101 Extension of Port Limits of Indianapolis, IN... Protection (CBP) is extending the geographical limits of the port of entry of Indianapolis, Indiana. This..., CBP proposed to amend the list of CBP ports of entry at 19 CFR 101.3(b)(1) to extend the limits of...

  14. 7 CFR 322.20 - Ports of entry.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Organisms § 322.20 Ports of entry. A restricted organism may be imported only at a port of entry staffed by an APHIS inspector. 5 After a restricted organism has been cleared for importation at the port of entry, the organism can only be transported by a bonded commercial carrier immediately and directly...

  15. 7 CFR 322.20 - Ports of entry.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Organisms § 322.20 Ports of entry. A restricted organism may be imported only at a port of entry staffed by an APHIS inspector. 5 After a restricted organism has been cleared for importation at the port of entry, the organism can only be transported by a bonded commercial carrier immediately and directly...

  16. Experiences in porting NASTRAN (R) to non-traditional platforms

    NASA Technical Reports Server (NTRS)

    Davis, Gregory L.; Norton, Robert L.

    1991-01-01

    The 1990 UNIX version of NASTRAN was ported to two new platforms that are not supported by COSMIC: the Sun SPARC workstation and the Apple Macintosh using the A/UX version of UNIX. The experiences of the authers in porting NASTRAN is summarized here. Suggestions for users who might attempt similar ports are given.

  17. 19 CFR 122.92 - Procedure at port of origin.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 1 2013-04-01 2013-04-01 false Procedure at port of origin. 122.92 Section 122.92... port of origin. (a) Forms required—(1) Customs Form 7512 or other document. Customs Form 7512 or other... Customs at the port of origin for merchandise for immediate transportation without appraisement....

  18. 19 CFR 122.92 - Procedure at port of origin.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 1 2012-04-01 2012-04-01 false Procedure at port of origin. 122.92 Section 122.92... port of origin. (a) Forms required—(1) Customs Form 7512 or other document. Customs Form 7512 or other... Customs at the port of origin for merchandise for immediate transportation without appraisement....

  19. 19 CFR 122.92 - Procedure at port of origin.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 1 2014-04-01 2014-04-01 false Procedure at port of origin. 122.92 Section 122.92... port of origin. (a) Forms required—(1) Customs Form 7512 or other document. Customs Form 7512 or other... Customs at the port of origin for merchandise for immediate transportation without appraisement....

  20. 19 CFR 122.92 - Procedure at port of origin.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false Procedure at port of origin. 122.92 Section 122.92... port of origin. (a) Forms required—(1) Customs Form 7512 or other document. Customs Form 7512 or other... Customs at the port of origin for merchandise for immediate transportation without appraisement....

  1. Electromagnetic Analysis For The Design Of ITER Diagnostic Port Plugs During Plasma Disruptions

    SciTech Connect

    Zhai, Y

    2014-03-03

    ITER diagnostic port plugs perform many functions including structural support of diagnostic systems under high electromagnetic loads while allowing for diagnostic access to plasma. The design of diagnotic equatorial port plugs (EPP) are largely driven by electromagnetic loads and associate response of EPP structure during plasma disruptions and VDEs. This paper summarizes results of transient electromagnetic analysis using Opera 3d in support of the design activities for ITER diagnostic EPP. A complete distribution of disruption loads on the Diagnostic First Walls (DFWs). Diagnostic Shield Modules (DSMs) and the EPP structure, as well as impact on the system design integration due to electrical contact among various EPP structural components are discussed.

  2. Overview of United States coal export terminals. [Includes description of present coal port terminal facilities

    SciTech Connect

    Not Available

    1980-09-01

    Existing coal export ports in the United States are in general not designed to the standards compatible with the current state of the art. The United States has a current coal export capacity in the order of 83 million tons per year. This could be increased to 138 million tons per year through a process of modernization and expansion which would take about six to eight years for full realization. Even if this expansion program took place it would not result in an overall coal export system that was economically competitive due to the fact that our export terminals are generally outmoded and cannot accommodate the large vessels engaged in the world coal trade and which can be accommodated at the major coal destination ports in Europe and Japan. In order for the United States to achieve an economically competitive posture in the world coal trade, new ports that will handle 150,000 to 250,000 DWT ships are needed. The new terminals must be designed to receive coal efficiently and minimize the demurrage costs for both railcars on the delivery side and ships on the load out side. There are port sites available in the US which could be developed to effectively handle the increased requirements. Each major new port could easily be designed to handle 20 to 50 million tons per year at ultimate capacity subject to the availability of coal from the source at a reasonable cost. New port construction is needed to satisfy the projected demand at a reasonable cost and to provide for the obsolescence of existing facilities. Decisions are needed now so that the ports will be operating 20 years from now and serve as replacements for present facilities which are becoming obsolete. The government of the United States can and must play a major role if success is to be achieved.

  3. I-PORT: new "hands-free" near-eye display

    NASA Astrophysics Data System (ADS)

    Carollo, Jerome T.; Hoppe, Michael

    2007-04-01

    The patent pending I-PORT TM is a highly versatile, hands-free, low profile near-eye display system. It was originally designed with the medical market in mind as a data (monocular) or surgical (binocular) head worn display. The concept takes advantage of a technique used with surgical loupes where they are sometimes mounted "into" eyeglasses. The I-PORT TMdisplay module is similarly mounted onto or into the spectacle lens of protective eyewear or sunglasses. The I-PORT TM is capable of various fields of view and resolutions while being low profile providing minimal obscuration. It is an ideal remote viewer for medical, military and commercial equipment. Our system is capable of producing fields of view greater than 50 degrees in full color and can incorporate either organic light emitting diode, (OLED) or active matrix liquid crystal display (AMLCD) image sources of various resolutions.

  4. Low-dose radiation pretreatment improves survival of human ceiling culture-derived proliferative adipocytes (ccdPAs) under hypoxia via HIF-1 alpha and MMP-2 induction

    SciTech Connect

    Adachi, Naoki; Kubota, Yoshitaka; Kosaka, Kentarou; Akita, Shinsuke; Sasahara, Yoshitarou; Kira, Tomoe; Kuroda, Masayuki; Mitsukawa, Nobuyuki; Bujo, Hideaki; Satoh, Kaneshige

    2015-08-07

    Poor survival is a major problem of adipocyte transplantation. We previously reported that VEGF and MMPs secreted from transplanted adipocytes are essential for angiogenesis and adipogenesis. Pretreatment with low-dose (5 Gy) radiation (LDR) increased VEGF, MMP-2, and HIF-1 alpha mRNA expression in human ceiling culture-derived proliferative adipocytes (hccdPAs). Gene expression after LDR differed between adipose-derived stem cells (hASCs) and hccdPAs. Pretreatment with LDR improved the survival of hccdPAs under hypoxia, which is inevitable in the early stages after transplantation. Upregulation of VEGF and MMP-2 after LDR in hccdPAs is mediated by HIF-1 alpha expression. Our results suggest that pretreatment with LDR may improve adipocyte graft survival in a clinical setting through upregulation of VEGF and MMP-2 via HIF-1 alpha. - Highlights: • Ceiling culture-derived proliferative adipocytes (ccdPAs) react to radiation. • Low-dose radiation (LDR) pretreatment improves survival of ccdPAs under hypoxia. • Gene expression after LDR differs between ccdPAs and adipose-derived stem cells. • LDR-induced increase in MMP-2 and VEGF is dependent on HIF-1 alpha induction. • LDR pretreatment may improve the adipocyte graft survival rate in clinical settings.

  5. 19 CFR 4.89 - Vessels in foreign trade proceeding via domestic ports and touching at intermediate foreign ports.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false Vessels in foreign trade proceeding via domestic ports and touching at intermediate foreign ports. 4.89 Section 4.89 Customs Duties U.S. CUSTOMS AND... DOMESTIC TRADES Coastwise Procedure § 4.89 Vessels in foreign trade proceeding via domestic ports...

  6. 19 CFR 4.89 - Vessels in foreign trade proceeding via domestic ports and touching at intermediate foreign ports.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Vessels in foreign trade proceeding via domestic ports and touching at intermediate foreign ports. 4.89 Section 4.89 Customs Duties U.S. CUSTOMS AND... DOMESTIC TRADES Coastwise Procedure § 4.89 Vessels in foreign trade proceeding via domestic ports...

  7. EPA Agreement with Port Authority and Port Terminal Operators Will Cut Harmful Pollution from Idling Trucks in Newark and Beyond

    EPA Pesticide Factsheets

    (New York, N.Y.) The U.S. Environmental Protection Agency announced agreements with the Port Authority of New York & New Jersey and port terminal operators that will cut harmful air pollution from the Port of New York and New Jersey. Under the agreemen

  8. 78 FR 42587 - Deepwater Port License: Amendment of the Neptune LNG LLC Deepwater Port License and Temporary...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-16

    ... Maritime Administration Deepwater Port License: Amendment of the Neptune LNG LLC Deepwater Port License and Temporary Suspension of Operations at the Neptune LNG Deepwater Port AGENCY: Maritime Administration... Administration (MarAd) provides public notice of its decision to approve the request of Neptune LNG LLC...

  9. Geometry and petrophysical parameters of a calcarenitic turbidite lobe (Barremian-Aptian, Pas-de-la-Cluse, France)

    NASA Astrophysics Data System (ADS)

    Savary, Bérengère; Ferry, Serge

    2004-06-01

    Several bioclastic resedimentation systems, late Barremian to early Aptian in age, outcrop in southeastern France. The upslope portion of a calcarenitic turbidite lobe outcrops as a cliff, 2.3 km wide and up to 45 m high, oriented roughly perpendicular to the direction of palaeoflow. It has been studied through 31 sections. The studied body is point-sourced and corresponds to a channel/lobe transition located at the toe-of-slope of a Urgonian carbonate platform on the western edge of the Vocontian Trough (French Subalpine Chains). The internal geometry of the lobe is the result of repeated erosion and filling of channels, creating well-defined stacked units. Filling phases result in lobe-shaped morphology. Units evolve from base to top in an ordered way. First, the sediments exported from the platform and deposited in the basin are represented by decimetre-thick, sheet-like and fine-grained Bouma a-e and ab-e sequences. In this first unit, erosion is limited and represented by shallow and symmetrical channels. This initial phase of deposition corresponds to the formation of a lobe with a positive morphology. The next phase of system development is more erosional and this is dominated by migrating, sinuous channels several metres deep filled with coarse-grained, poorly graded turbidites. These channels are first filled through lateral accretion and then sediment spills over to create a sub-lobe. The mixture of channel and lobe features could be considered as a carbonate equivalent of the channel-levee system of siliciclastic deposits. Finally, the system ends with the deposition of a flat-based unit. This unit extends for more than 2 km and is composed of the southwards lateral accretion of hundreds of metres wide sequences each composed of a debris-flow deposit capped by a coarse-grained calcarenite bed. These sigmoidal bodies could be the ultimate forms of a spreading out phenomenon of the lobe. Overall, the Pas-de-la-Cluse system is a coarsening-upward body. As

  10. The Potential for Biomass District Energy Production in Port Graham, Alaska

    SciTech Connect

    Charles Sink, Chugachmiut; Keeryanne Leroux, EERC

    2008-05-08

    This project was a collaboration between The Energy & Environmental Research Center (EERC) and Chugachmiut – A Tribal organization Serving the Chugach Native People of Alaska and funded by the U.S. Department of Energy (DOE) Tribal Energy Program. It was conducted to determine the economic and technical feasibility for implementing a biomass energy system to service the Chugachmiut community of Port Graham, Alaska. The Port Graham tribe has been investigating opportunities to reduce energy costs and reliance on energy imports and support subsistence. The dramatic rise in the prices of petroleum fuels have been a hardship to the village of Port Graham, located on the Kenai Peninsula of Alaska. The Port Graham Village Council views the forest timber surrounding the village and the established salmon industry as potential resources for providing biomass energy power to the facilities in their community. Benefits of implementing a biomass fuel include reduced energy costs, energy independence, economic development, and environmental improvement. Fish oil–diesel blended fuel and indoor wood boilers are the most economical and technically viable options for biomass energy in the village of Port Graham. Sufficient regional biomass resources allow up to 50% in annual heating savings to the user, displacing up to 70% current diesel imports, with a simple payback of less than 3 years for an estimated capital investment under $300,000. Distributive energy options are also economically viable and would displace all imported diesel, albeit offering less savings potential and requiring greater capital. These include a large-scale wood combustion system to provide heat to the entire village, a wood gasification system for cogeneration of heat and power, and moderate outdoor wood furnaces providing heat to 3–4 homes or community buildings per furnace. Coordination of biomass procurement and delivery, ensuring resource reliability and technology acceptance, and arbitrating

  11. Evaluation and Repair of War-Damaged Port Facilities. Report 1. Port Construction History, Inspection Techniques, and Major Port Characteristics.

    DTIC Science & Technology

    1986-05-01

    civilian techniques ; and to develop data sheets that identify major ports with special characteristics. 2. The scope of this investigation included a...military confrontations. Numerous state-of-the-art inspection techniques have been developed to assess deterioration to waterfront facilities. These...number of NDT techniques have been developed either in laboratories or fac- tories; however, only five have found application in underwater

  12. Low Back Pain in Port Machinery Operators

    NASA Astrophysics Data System (ADS)

    BOVENZI, M.; PINTO, I.; STACCHINI, N.

    2002-05-01

    The occurrence of several types of low back pain (LBP) was investigated by a standardized questionnaire in a group of 219 port machinery operators exposed to whole-body vibration (WBV) and postural load and in a control group of 85 maintenance workers employed at the same transport company. The group of port machinery operators included 85 straddle carrier drivers, 88 fork-lift truck drivers, and 46 crane operators. The vector sum of the frequency-weighted r.m.s. acceleration of vibration measured on the seatpan of port vehicles and machines averaged 0·90 m/s2 for fork-lift trucks, 0·48 m/s2 for straddle carriers, 0·53 m/s2 for mobile cranes, and 0·22 m/s2 for overhead cranes. The 12-month prevalence of low back symptoms (LBP, sciatic pain, treated LBP, sick leave due to LBP) was significantly greater in the fork-lift truck drivers than in the controls and the other two groups of port machinery operators. After adjusting for potential confounders, the prevalence of low back symptoms was found to increase with the increase of WBV exposure expressed as duration of exposure (driving years), equivalent vibration magnitude (m/s2), or cumulative vibration exposure (yr m2/s4). An excess risk for lumbar disc herniation was observed in the port machinery operators with prolonged driving experience. In both the controls and the port machinery operators, low back complaints were strongly associated with perceived postural load assessed in terms of frequency and/or duration of awkward postures at work. Multivariate analysis showed that vibration exposure and postural load were independent predictors of LBP. Even though the cross-sectional design of the present study does not permit firm conclusions on the relationship between WBV exposure and low back disorders, the findings of this investigation provide additional epidemiological evidence that seated WBV exposure combined with non-neutral trunk postures, as while driving, is associated with an increased risk of long

  13. Microwave powered sterile access port

    NASA Technical Reports Server (NTRS)

    Sauer, Richard L. (Inventor); Atwater, James E. (Inventor); Dahl, Roger W. (Inventor); Garmon, Frank C. (Inventor); Lunsford, Teddie D. (Inventor); Michalek, William F. (Inventor); Wheeler, Jr., Richard R. (Inventor)

    2000-01-01

    A device and method for elimination of contamination during transfer of materials either into or from bioreactors, food containers, or other microbially vulnerable systems. Using microwave power, thermal sterilizations of mating fixtures are achieved simply, reliably, and quickly by the volatilization of small quantities of water to produce superheated steam which contacts all exposed surfaces.

  14. Detecting and Characterizing Semantic Inconsistencies in Ported Code

    NASA Technical Reports Server (NTRS)

    Ray, Baishakhi; Kim, Miryung; Person, Suzette J.; Rungta, Neha

    2013-01-01

    Adding similar features and bug fixes often requires porting program patches from reference implementations and adapting them to target implementations. Porting errors may result from faulty adaptations or inconsistent updates. This paper investigates (I) the types of porting errors found in practice, and (2) how to detect and characterize potential porting errors. Analyzing version histories, we define five categories of porting errors, including incorrect control- and data-flow, code redundancy, inconsistent identifier renamings, etc. Leveraging this categorization, we design a static control- and data-dependence analysis technique, SPA, to detect and characterize porting inconsistencies. Our evaluation on code from four open-source projects shows thai SPA can dell-oct porting inconsistencies with 65% to 73% precision and 90% recall, and identify inconsistency types with 58% to 63% precision and 92% to 100% recall. In a comparison with two existing error detection tools, SPA improves precision by 14 to 17 percentage points

  15. Detecting and Characterizing Semantic Inconsistencies in Ported Code

    NASA Technical Reports Server (NTRS)

    Ray, Baishakhi; Kim, Miryung; Person,Suzette; Rungta, Neha

    2013-01-01

    Adding similar features and bug fixes often requires porting program patches from reference implementations and adapting them to target implementations. Porting errors may result from faulty adaptations or inconsistent updates. This paper investigates (1) the types of porting errors found in practice, and (2) how to detect and characterize potential porting errors. Analyzing version histories, we define five categories of porting errors, including incorrect control- and data-flow, code redundancy, inconsistent identifier renamings, etc. Leveraging this categorization, we design a static control- and data-dependence analysis technique, SPA, to detect and characterize porting inconsistencies. Our evaluation on code from four open-source projects shows that SPA can detect porting inconsistencies with 65% to 73% precision and 90% recall, and identify inconsistency types with 58% to 63% precision and 92% to 100% recall. In a comparison with two existing error detection tools, SPA improves precision by 14 to 17 percentage points.

  16. [Laparoscopic cholecystectomy with three-port and 25 millimeters long incision.

    PubMed

    Gómez Tagle-Morales, Enrique David

    2013-01-01

    Background: three-port and 25 mm total incision laparoscopic cholecystectomy has shown benefits compared to conventional laparoscopy. The aim was to examine the safety and feasibility of this technique. Methods: a three-port laparoscopic cholecystectomy trial was conducted through Cinvestav metasearcher, Seriunam and Rencis. The eligibility criteria were: three port laparoscopic cholecystectomy, 25 mm total incision, and score = 17 on Data Review System. Trials which employed instruments smaller than 5 mm in diameter were excluded. The comparative variables were documented and results obtained in the selected trials were described. Results: four trials were selected, comprising 1767 cases (1329 females and 438 males), average age was 44.3 years. Chronic cholecystitis was documented in 84.3 %, and acute cholecystitis in 14.7 %. Average surgical time was 54.5 minutes. An additional port was required in 4.8 % and 1.4 % was converted to open technique. Bile duct injury was presented in 0.11 %. The success rate was 94.9 %. Conclusions: three port and 25 mm total incision in laparoscopic cholecystectomy is safe and feasible.

  17. [Superposition impact character of air pollution from decentralization docks in a freshwater port].

    PubMed

    Liu, Jian-chang; Li, Xing-hua; Xu, Hong-lei; Cheng, Jin-xiang; Wang, Zhong-dai; Xiao, Yang

    2013-05-01

    Air pollution from freshwater port is mainly caused by dust pollution, including material loading and unloading dust, road dust, and wind erosion dust from stockpile, bare soil. The dust pollution from a single dock characterized in obvious difference with air pollution from multiple scattered docks. Jining Port of Shandong Province was selected as a case study to get superposition impact contribution of air pollution for regional air environment from multiple scattered docks and to provide technical support for system evaluation of port air pollution. The results indicate that (1) the air pollution from freshwater port occupies a low proportion of pollution impact on regional environmental quality because the port is consisted of serveral small scattered docks; (2) however, the geometric center of the region distributed by docks is severely affected with the most superposition of the air pollution; and (3) the ADMS model is helpful to attain an effective and integrated assessment to predict a superposition impact of multiple non-point pollution sources when the differences of high-altitude weather conditions was not considered on a large scale.

  18. Reducing Vulnerability of Ports and Harbors to Earthquake and Tsunami Hazards

    USGS Publications Warehouse

    Wood, Nathan J.; Good, James W.; Goodwin, Robert F.

    2002-01-01

    Recent scientific research suggests the Pacific Northwest could experience catastrophic earthquakes in the near future, both from distant and local sources, posing a significant threat to coastal communities. Damage could result from numerous earthquake-related hazards, such as severe ground shaking, soil liquefaction, landslides, land subsidence/uplift, and tsunami inundation. Because of their geographic location, ports and harbors are especially vulnerable to these hazards. Ports and harbors, however, are important components of many coastal communities, supporting numerous activities critical to the local and regional economy and possibly serving as vital post-event, response-recovery transportation links. A collaborative, multi-year initiative is underway to increase the resiliency of Pacific Northwest ports and harbors to earthquake and tsunami hazards, involving Oregon Sea Grant (OSG), Washington Sea Grant (WSG), the National Oceanic and Atmospheric Administration Coastal Services Center (CSC), and the U.S. Geological Survey Center for Science Policy (CSP). Specific products of this research, planning, and outreach initiative include a regional stakeholder issues and needs assessment, a community-based mitigation planning process, a Geographic Information System (GIS) — based vulnerability assessment methodology, an educational web-site and a regional data archive. This paper summarizes these efforts, including results of two pilot port-harbor community projects, one in Yaquina Bay, Oregon and the other in Sinclair Inlet, Washington. Finally, plans are outlined for outreach to other port and harbor communities in the Pacific Northwest and beyond, using "getting started" workshops and a web-based tutorial.

  19. A comparative study of two-port versus three-port laparoscopic cholecystectomy

    PubMed Central

    Hajong, Ranendra; Khariong, Peter DS

    2016-01-01

    BACKGROUND: Conventionally, laparoscopic cholecystectomy (LC) is performed by using three or four ports of various sizes. As cosmesis is an important aspect of LC, the trend is now towards use of fewer ports, thereby resulting in better cosmesis for patients. The aim of this study was to compare three-port against two-port LC techniques and to see whether there is any advantage in using one technique over the other. SETTINGS AND DESIGN: The study was conducted in the Department of General Surgery of North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences (NEIGRIHMS) hospital in Northeast India. A prospective comparative type of study was designed. An odd number of patients were operated on by using the three-port technique (Group A), whereas an even number of patients were operated on by the two-port technique (Group B). MATERIALS AND METHODS: Sixty patients with symptomatic gallstone disease were included in the study after obtaining informed consent from each of the patients. All patients were operated on under general anaesthesia. STATISTICAL ANALYSIS USED: Statistical analysis was done using SPSS software version 22. RESULTS: There were 51 female patients and 9 male patients. The mean patient age was 38.67 years. There was less operative time in group A but less postoperative pain in group B. Cosmetic appearance and patient satisfaction for the scar were better in group B. CONCLUSIONS: The two-port method appeared to have better acceptability among patients due to lower pain score and better cosmesis. PMID:27251814

  20. Abdominal anatomy in the context of port placement and trocars

    PubMed Central

    Alkatout, Ibrahim; Mettler, Liselotte; Maass, Nicolai; Noé, Günter-Karl; Elessawy, Mohamed

    2015-01-01

    Although the anatomy of the human being has not changed, technical developments in operating materials and methods demand a simultaneous development in operative management. Developments in electronic and optical technologies permit many gynecological operations to be performed laparoscopically. One fundamental distinction between any other operating method and laparoscopy is the hurdle that the initial entry, whether with a needle, cannula, or trocar, is mostly performed blind. However, there is a risk that blind entry may result in vascular or organ damage. One of the difficulties associated with entry complications is that any damage may not be immediately recognized, leading to major abdominal reparative surgery, and at worst, a temporary colostomy. Therefore, the technical and operative quality of laparoscopic surgery begins with port placement and trocars. Visual access systems are available but are not yet widely used. The aim of this review was to introduce the different port placement and trocar systems as well as their correct and professional usage in correlation with the abdominal functional anatomy. PMID:26692776

  1. Laser Treatment of Port Wine Stains

    NASA Astrophysics Data System (ADS)

    Majaron, Boris; Nelson, J. Stuart

    Port wine stain (PWS), also called nevus flammeus, is a congenital, cutaneous vascular malformation involving post-capillary venules which produce a light pink to red to dark-red-violet discoloration of human skin [1]. PWS occurs in an estimated 3 children per 1000 live births, affecting males and females and all racial groups equally [2]. There appears to be no hereditary predilection for PWS within families. There are no known risk factors or ways to prevent PWS.

  2. Port navigation: let the journey begin.

    PubMed

    Arch, Penelope

    2007-08-01

    Central venous access plays an important role in modern medical patient assessment and treatment. The use of central venous access devices has become routine in the oncology setting. Clinical oncology nurses need to know how the devices function, how to provide proper care, and how to manage potential side effects. The focus of this article will be on the navigation of implanted, skin-tunneled ports.

  3. Design and tritium permeation analysis of China HCCB TBM port cell

    SciTech Connect

    Jiangfeng, S.; Guoqiang, H.; Zhiyong, H.; Chang'an, C.; Deli, L.

    2015-03-15

    China is planning to develop a helium-cooled ceramic breeder (HCCB) test blanket module (TBM) on ITER to test key blanket technologies. In this paper, the design and tritium permeation analysis of China HCCB TBM port cell are introduced. A theoretical model has been developed to estimate tritium permeation rates and leak rates from the components and pipes which China has scheduled to house in the port cell. It is shown that on normal working conditions, the permeation and leak rate of the systems in the port cell will be no higher than 1.58 Ci/d without the use of tritium permeation barriers, and 0.10 Ci/d with the use of tritium permeation barriers. It also appears that tritium permeation barriers are necessary for high temperature components such as the reduction bed and the heater.

  4. Underwater Calibration of Dome Port Pressure Housings

    NASA Astrophysics Data System (ADS)

    Nocerino, E.; Menna, F.; Fassi, F.; Remondino, F.

    2016-03-01

    Underwater photogrammetry using consumer grade photographic equipment can be feasible for different applications, e.g. archaeology, biology, industrial inspections, etc. The use of a camera underwater can be very different from its terrestrial use due to the optical phenomena involved. The presence of the water and camera pressure housing in front of the camera act as additional optical elements. Spherical dome ports are difficult to manufacture and consequently expensive but at the same time they are the most useful for underwater photogrammetry as they keep the main geometric characteristics of the lens unchanged. Nevertheless, the manufacturing and alignment of dome port pressure housing components can be the source of unexpected changes of radial and decentring distortion, source of systematic errors that can influence the final 3D measurements. The paper provides a brief introduction of underwater optical phenomena involved in underwater photography, then presents the main differences between flat and dome ports to finally discuss the effect of manufacturing on 3D measurements in two case studies.

  5. Single port laparoscopic orchidopexy in children using surgical glove port and conventional rigid instruments

    PubMed Central

    Mahdi, Ben Dhaou; Mohamed, Jallouli; Hayet, Zitouni; Riadh, Mhiri

    2015-01-01

    Purpose We review the literature and describe our technique for laparoendoscopic single-site orchidopexy using a glove port and rigid instruments. We assessed the feasibility and outcomes of this procedure. Materials and Methods We retrospectively reviewed the case records of all children who had undergone laparoendoscopic single-site orchidopexy by use of a surgical glove port and conventional rigid instruments for a nonpalpable intraabdominal testis between January 2013 and September 2014. Results Data from a total of 20 patients were collected. The patients' mean age was 18 months. All cases had a nonpalpable unilateral undescended testis. Fourteen patients (70%) had an undescended testis on the right side and six patients (30%) had an undescended testis on the left side. Seventeen patients underwent primary orchidopexy. Three patients underwent single-port laparoscopic Fowler-Stephens orchidopexy for the first and the second stage. Average operating time was 57 minutes (range, 40 to 80 minutes). No patient was lost to follow-up. At follow-up, 2 testes were found to have retracted out of the scrotum and these were successfully dealt with in a second operation. One testis was hypoplastic in the scrotal pouch. There were no signs of umbilical hernia. Conclusions Single-port laparoscopic orchidopexy using a glove port and rigid instruments is technically feasible and safe for various nonpalpable intraabdominal testes. However, surgical experience and long-term follow-up are needed to confirm the superiority of this technique. PMID:26568797

  6. Closeup view from the starboard side looking towards the port ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Close-up view from the starboard side looking towards the port side of the Orbiter Discovery looking at the airlock and payload bay. The docking ring has been removed from the airlock prior to this photo being taken. Note that the Orbiter Boom Sensor System is still attached while the Remote Manipulator System has been removed. Also note the suspended protective panels and walkways in place to protect the interior surfaces of the payload bay doors while in their open position. This view was taken from a service platform in the Orbiter Processing Facility at Kennedy Space Center. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  7. Radiological Interventions for Correction of Central Venous Port Catheter Migrations

    SciTech Connect

    Gebauer, Bernhard Teichgraeber, Ulf Karl; Podrabsky, Petr; Werk, Michael; Haenninen, Enrique Lopez; Felix, Roland

    2007-07-15

    Purpose. The purpose of this study was to evaluate radiological-interventional central venous port catheter corrections in migrated/malpositioned catheter tips. Materials and Methods. Thirty patients with migrated/malpositioned port catheter tips were included in this retrospective analysis. To visualize the catheter patency a contrast-enhanced port catheter series was performed, followed by transfemoral port catheter correction with various 5-F angiographic catheters (pigtail; Sos Omni), gooseneck snares, or combinations thereof. Results. One patient showed spontaneous reposition of the catheter tip. In 27 of 29 patients (93%), radiological-interventional port catheter correction was successful. In two patients port catheter malposition correction was not possible, because of the inability to catch either the catheter tip or the catheter in its course, possibly due to fibrin sheath formation with attachment of the catheter to the vessel wall. No disconnection or port catheter dysfunction was observed after correction. Conclusions. We conclude that in migrated catheter tips radiological-interventional port catheter correction is a minimally invasive alternative to port extraction and reimplantation. In patients with a fibrin sheath and/or thrombosis port catheter correction is often more challenging.

  8. 75 FR 34929 - Safety Zones: Neptune Deep Water Port, Atlantic Ocean, Boston, MA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-21

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zones: Neptune Deep Water Port, Atlantic Ocean... turret loading (STL) buoys and accompanying systems that are part of GDF Suez Energy's Neptune Deepwater... of a final regulatory action, which will be proposed in a separate rulemaking docket titled:...

  9. Combined laser and surgical treatment of giant port wine stain malformation - Case report

    NASA Astrophysics Data System (ADS)

    Siewiera, I.; Drozdowski, P.; Wójcicki, P.

    2012-10-01

    Background:Port-wine stains (PWS) are vascular malformations of the skin concerning about 0,3% of the population. Though various laser systems have been used for various treatment regimens the treatment of PWS of large size is especially difficult and demanding from aesthetic and psychological point of view.

  10. Second Line of Defense, Megaports Initiative, Operational Testing and Evaluation Plan, Port of Lazaro Cardenas, Mexico

    SciTech Connect

    Hughes, Jamie D.

    2012-05-30

    The purpose of the Operational Testing and Evaluation (OT&E) phases of the project is to prepare for turnover of the Megaports System supplied by U.S. Department of Energy/National Nuclear Security Administration (DOE/NNSA)—located at the Export Lanes of the Port of Lazaro Cardenas, Mexico—to the Government of Mexico (GOM).

  11. Higher-dimensional performance of port-based teleportation.

    PubMed

    Wang, Zhi-Wei; Braunstein, Samuel L

    2016-09-08

    Port-based teleportation (PBT) is a variation of regular quantum teleportation that operates without a final unitary correction. However, its behavior for higher-dimensional systems has been hard to calculate explicitly beyond dimension d = 2. Indeed, relying on conventional Hilbert-space representations entails an exponential overhead with increasing dimension. Some general upper and lower bounds for various success measures, such as (entanglement) fidelity, are known, but some become trivial in higher dimensions. Here we construct a graph-theoretic algebra (a subset of Temperley-Lieb algebra) which allows us to explicitly compute the higher-dimensional performance of PBT for so-called "pretty-good measurements" with negligible representational overhead. This graphical algebra allows us to explicitly compute the success probability to distinguish the different outcomes and fidelity for arbitrary dimension d and low number of ports N, obtaining in addition a simple upper bound. The results for low N and arbitrary d show that the entanglement fidelity asymptotically approaches N/d(2) for large d, confirming the performance of one lower bound from the literature.

  12. Higher-dimensional performance of port-based teleportation

    PubMed Central

    Wang, Zhi-Wei; Braunstein, Samuel L.

    2016-01-01

    Port-based teleportation (PBT) is a variation of regular quantum teleportation that operates without a final unitary correction. However, its behavior for higher-dimensional systems has been hard to calculate explicitly beyond dimension d = 2. Indeed, relying on conventional Hilbert-space representations entails an exponential overhead with increasing dimension. Some general upper and lower bounds for various success measures, such as (entanglement) fidelity, are known, but some become trivial in higher dimensions. Here we construct a graph-theoretic algebra (a subset of Temperley-Lieb algebra) which allows us to explicitly compute the higher-dimensional performance of PBT for so-called “pretty-good measurements” with negligible representational overhead. This graphical algebra allows us to explicitly compute the success probability to distinguish the different outcomes and fidelity for arbitrary dimension d and low number of ports N, obtaining in addition a simple upper bound. The results for low N and arbitrary d show that the entanglement fidelity asymptotically approaches N/d2 for large d, confirming the performance of one lower bound from the literature. PMID:27605383

  13. Higher-dimensional performance of port-based teleportation

    NASA Astrophysics Data System (ADS)

    Wang, Zhi-Wei; Braunstein, Samuel L.

    2016-09-01

    Port-based teleportation (PBT) is a variation of regular quantum teleportation that operates without a final unitary correction. However, its behavior for higher-dimensional systems has been hard to calculate explicitly beyond dimension d = 2. Indeed, relying on conventional Hilbert-space representations entails an exponential overhead with increasing dimension. Some general upper and lower bounds for various success measures, such as (entanglement) fidelity, are known, but some become trivial in higher dimensions. Here we construct a graph-theoretic algebra (a subset of Temperley-Lieb algebra) which allows us to explicitly compute the higher-dimensional performance of PBT for so-called “pretty-good measurements” with negligible representational overhead. This graphical algebra allows us to explicitly compute the success probability to distinguish the different outcomes and fidelity for arbitrary dimension d and low number of ports N, obtaining in addition a simple upper bound. The results for low N and arbitrary d show that the entanglement fidelity asymptotically approaches N/d2 for large d, confirming the performance of one lower bound from the literature.

  14. Fuel injection control based on spill port opening timing correction

    SciTech Connect

    Ban, M.; Miyaki, M.; Hasegawa, T.; Kobayashi, F.; Kobashi, M.

    1988-08-30

    This patent describes a fuel injection control system for an internal combustion engine, comprising: (a) a fuel injection pump including: a pump chamber; a low pressure chamber; plunger means reciprocating in synchronism with rotation of the engine for introducing fuel into the pump chamber, and for feeding the fuel under pressure from the pump chamber to a cylinder of the engine, detector means for detecting a reference position of the plunger, and for generating a detection signal indicative of the reference position, and a spill port coupled to the pump chamber and in communication with the low pressure chamber, (b) solenoid valve means for opening and closing the spill port; (c) first circuit means including first and second adjusting resistors, the first circuit means being replaceably disposed on the fuel injection pump; (d) first control means for calculating a fuel injection time period according to operating conditions of the engine; (e) second control means including second circuit means comprising first and second fixed resistors, the first fixed resistor being connected to the first adjusting resistor so as to produce a first voltage signal corresponding to a ratio of a resistance value of the first adjusting resistor to a resistance value of the first fixed resistor.

  15. Modeling the uptake of neutral organic chemicals on XAD passive air samplers under variable temperatures, external wind speeds and ambient air concentrations (PAS-SIM).

    PubMed

    Armitage, James M; Hayward, Stephen J; Wania, Frank

    2013-01-01

    The main objective of this study was to evaluate the performance and demonstrate the utility of a fugacity-based model of XAD passive air samplers (XAD-PAS) designed to simulate the uptake of neutral organic chemicals under variable temperatures, external wind speeds and ambient air concentrations. The model (PAS-SIM) simulates the transport of the chemical across the air-side boundary layer and within the sampler medium, which is segmented into a user-defined number of thin layers. Model performance was evaluated using data for polychlorinated biphenyls (PCBs) and polycyclic aromatic hydrocarbons (PAHs) from a field calibration study (i.e., active and XAD-PAS data) conducted in Egbert, Ontario, Canada. With some exceptions, modeled PAS uptake curves are in good agreement with the empirical PAS data. The results are highly encouraging, given the uncertainty in the active air sampler data used as input and other uncertainties related to model parametrization (e.g., sampler-air partition coefficients, the influence of wind speed on sampling rates). The study supports the further development and evaluation of the PAS-SIM model as a diagnostic (e.g., to aid interpretation of calibration studies and monitoring data) and prognostic (e.g., to inform design of future passive air sampling campaigns) tool.

  16. 33 CFR 165.809 - Security Zones; Port of Port Lavaca-Point Comfort, Point Comfort, TX and Port of Corpus Christi...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Lavaca-Point Comfort, Point Comfort, TX and Port of Corpus Christi Inner Harbor, Corpus Christi, TX. 165... Lavaca-Point Comfort, Point Comfort, TX and Port of Corpus Christi Inner Harbor, Corpus Christi, TX. (a) Location. The following area is designated as a security zone: all waters of the Corpus Christi...

  17. Subclavian Vein Versus Arm Vein for Totally Implantable Central Venous Port for Patients with Head and Neck Cancer: A Retrospective Comparative Analysis

    SciTech Connect

    Akahane, Akio Sone, Miyuki; Ehara, Shigeru; Kato, Kenichi; Tanaka, Ryoichi; Nakasato, Tatsuhiko

    2011-12-15

    Purpose: This study was designed to compare central venous ports (CVP) from two different routes of venous access-the subclavian vein and arm vein-in terms of safety for patients with head and neck cancer (HNC). Methods: Patients with HNC who underwent image-guided implantations of CVPs were retrospectively evaluated. All CVPs were implanted under local anesthesia. Primary outcome measurements were rates and types of adverse events (AEs). Secondary outcomes included technical success and rate and reason of CVP removal. Results: A total of 162 patients (subclavian port group, 47; arm port group, 115) were included in this study. Technical success was achieved in all patients. The median follow-up period was 94 (range, 1-891) days. Two patients in the subclavian port group experienced periprocedural complications. Postprocedural AEs were observed in 8.5 and 22.6% of the subclavian port and arm port group patients, respectively (P = 0.044). Phlebitis and system occlusions were observed only in the arm port group. The rate of infection was not significantly different between the two groups. The CVP was removed in 34 and 39.1% of the subclavian port and arm port patients, respectively. Conclusions: Both subclavian and arm CVPs are feasible in patients with HNC. AEs were more frequent in the arm port group; thus, the arm port is not recommended as the first choice for patients with HNC. However, further experience is needed to improve the placement technique and the maintenance of CVPs and a prospective analysis is warranted.

  18. General view of the middeck looking aft and port. In ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of the mid-deck looking aft and port. In this view you can clearly see the crew access hatch and the airlock hatch. The hose and ladder in the image are pieces of ground support equipment. The hose is part of the climate control apparatus used while orbiters are being processed. The ladder is used to access the inter-deck passage, leading to the flight deck, while the orbiter is in 1g (earth's gravity). A careful observer will notice a void in the wall near the base of the access ladder, this is the Waste Management Compartment with the Waste Management System, i.e. Space Potty, removed. This view was taken in the Orbiter Processing Facility at the Kennedy Space Center. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  19. Patient Positioning and Port Placement for Robot-Assisted Surgery

    PubMed Central

    Chang, Charles; Steinberg, Zoe; Shah, Anup

    2014-01-01

    Abstract The introduction of robotic surgical systems and their integration into minimally invasive procedures have changed the landscape of laparoscopic surgery dramatically. Intuitive Surgical's da Vinci Surgical System was first approved by the Food and Drug Administration for cardiothoracic procedures in the late 1990s. This trend quickly spread through other surgical specialties, with urologists as one of the frontrunners in adoption. Subsequently, pediatric urologists have adopted robot-assisted procedures in selected centers, performing procedures such as pyeloplasty for ureteropelvic junction obstruction, partial and complete nephrectomy, and both intravesical and extravesical ureteral reimplantation. In this article, we will discuss technical considerations related to patient positioning and port placement in pediatric robot-assisted surgery. PMID:24548088

  20. Investigations of the structural stability of highly strained [(Al)GaIn]As/Ga (PAs) multiple quantum wells

    NASA Astrophysics Data System (ADS)

    Marschner, T.; Lutgen, S.; Volk, M.; Stolz, W.; Göbel, E. O.

    1996-10-01

    The structural stability of highly strained [(Al)GaIn]As/Ga (PAs) strained layer superlattice (SLS) structures as a function of the average lattice mismatch is investigated. The SLS structures, grown by metalorganic vapor-phase epitaxy, are studied by using high-resolution x-ray diffraction. The range of stable SLS structures obtained experimentally is compared to a recent theoretical model assuming strain relaxation by formation of misfit dislocations [D. C. Houghton, M. Davies, and M. Dion, Appl. Phys. Lett. 64, 505 (1994)]. In particular, the influence of the surface migration length of the group-III species on the growth surface is investigated by varying the Al concentration in the compressively strained [(Al)GaIn]As layers. Structurally stable [(Al)GaIn]As/Ga(PAs) SLS structures having a total layer thickness of 1 μm and an average lattice mismatch of up to (Δd/d)⊥=1.2×10-2 have been realized. These values exceed by far the values of the misfit dislocation model. This behavior indicates that surface morphology changes rather than misfit dislocation formation are the primary cause for the instability of highly strained SLSs.

  1. Six-Port Based Interferometry for Precise Radar and Sensing Applications

    PubMed Central

    Koelpin, Alexander; Lurz, Fabian; Linz, Sarah; Mann, Sebastian; Will, Christoph; Lindner, Stefan

    2016-01-01

    Microwave technology plays a more important role in modern industrial sensing applications. Pushed by the significant progress in monolithic microwave integrated circuit technology over the past decades, complex sensing systems operating in the microwave and even millimeter-wave range are available for reasonable costs combined with exquisite performance. In the context of industrial sensing, this stimulates new approaches for metrology based on microwave technology. An old measurement principle nearly forgotten over the years has recently gained more and more attention in both academia and industry: the six-port interferometer. This paper reviews the basic concept, investigates promising applications in remote, as well as contact-based sensing and compares the system with state-of-the-art metrology. The significant advantages will be discussed just as the limitations of the six-port architecture. Particular attention will be paid to impairment effects and non-ideal behavior, as well as compensation and linearization concepts. It will be shown that in application fields, like remote distance sensing, precise alignment measurements, as well as interferometrically-evaluated mechanical strain analysis, the six-port architecture delivers extraordinary measurement results combined with high measurement data update rates for reasonable system costs. This makes the six-port architecture a promising candidate for industrial metrology. PMID:27669246

  2. Six-Port Based Interferometry for Precise Radar and Sensing Applications.

    PubMed

    Koelpin, Alexander; Lurz, Fabian; Linz, Sarah; Mann, Sebastian; Will, Christoph; Lindner, Stefan

    2016-09-22

    Microwave technology plays a more important role in modern industrial sensing applications. Pushed by the significant progress in monolithic microwave integrated circuit technology over the past decades, complex sensing systems operating in the microwave and even millimeter-wave range are available for reasonable costs combined with exquisite performance. In the context of industrial sensing, this stimulates new approaches for metrology based on microwave technology. An old measurement principle nearly forgotten over the years has recently gained more and more attention in both academia and industry: the six-port interferometer. This paper reviews the basic concept, investigates promising applications in remote, as well as contact-based sensing and compares the system with state-of-the-art metrology. The significant advantages will be discussed just as the limitations of the six-port architecture. Particular attention will be paid to impairment effects and non-ideal behavior, as well as compensation and linearization concepts. It will be shown that in application fields, like remote distance sensing, precise alignment measurements, as well as interferometrically-evaluated mechanical strain analysis, the six-port architecture delivers extraordinary measurement results combined with high measurement data update rates for reasonable system costs. This makes the six-port architecture a promising candidate for industrial metrology.

  3. SmartPort: A Platform for Sensor Data Monitoring in a Seaport Based on FIWARE.

    PubMed

    Fernández, Pablo; Santana, José Miguel; Ortega, Sebastián; Trujillo, Agustín; Suárez, José Pablo; Domínguez, Conrado; Santana, Jaisiel; Sánchez, Alejandro

    2016-03-22

    Seaport monitoring and management is a significant research area, in which infrastructure automatically collects big data sets that lead the organization in its multiple activities. Thus, this problem is heavily related to the fields of data acquisition, transfer, storage, big data analysis and information visualization. Las Palmas de Gran Canaria port is a good example of how a seaport generates big data volumes through a network of sensors. They are placed on meteorological stations and maritime buoys, registering environmental parameters. Likewise, the Automatic Identification System (AIS) registers several dynamic parameters about the tracked vessels. However, such an amount of data is useless without a system that enables a meaningful visualization and helps make decisions. In this work, we present SmartPort, a platform that offers a distributed architecture for the collection of the port sensors' data and a rich Internet application that allows the user to explore the geolocated data. The presented SmartPort tool is a representative, promising and inspiring approach to manage and develop a smart system. It covers a demanding need for big data analysis and visualization utilities for managing complex infrastructures, such as a seaport.

  4. SmartPort: A Platform for Sensor Data Monitoring in a Seaport Based on FIWARE

    PubMed Central

    Fernández, Pablo; Santana, José Miguel; Ortega, Sebastián; Trujillo, Agustín; Suárez, José Pablo; Domínguez, Conrado; Santana, Jaisiel; Sánchez, Alejandro

    2016-01-01

    Seaport monitoring and management is a significant research area, in which infrastructure automatically collects big data sets that lead the organization in its multiple activities. Thus, this problem is heavily related to the fields of data acquisition, transfer, storage, big data analysis and information visualization. Las Palmas de Gran Canaria port is a good example of how a seaport generates big data volumes through a network of sensors. They are placed on meteorological stations and maritime buoys, registering environmental parameters. Likewise, the Automatic Identification System (AIS) registers several dynamic parameters about the tracked vessels. However, such an amount of data is useless without a system that enables a meaningful visualization and helps make decisions. In this work, we present SmartPort, a platform that offers a distributed architecture for the collection of the port sensors’ data and a rich Internet application that allows the user to explore the geolocated data. The presented SmartPort tool is a representative, promising and inspiring approach to manage and develop a smart system. It covers a demanding need for big data analysis and visualization utilities for managing complex infrastructures, such as a seaport. PMID:27011192

  5. Is multi-port ATE in your future

    NASA Astrophysics Data System (ADS)

    Monie, V.; Kovel, D. M.

    The history of ATE is surveyed, with attention given to significant technical advances made during the past few years. Multi-port testing is seen as a logical extension of engineering attempts to extract the maximum value for the ATE dollar invested. Particular attention is given to the economics of multi-port ATE. It is shown that the cost/throughput ratio of a dual-port test set is 40% greater than a single port test set. The benefits of increased test set availability and the associated logistics costs are stressed. The numerous economic benefits are matched by the technical advantages, which are also discussed in detail. Potential problems in a dual-port ATE are identified, and solutions are suggested. It is shown that a successful dual-port ATE is one that not only solves real-life testing problems but also solves problems of resource competition and allocation.

  6. 77 FR 61727 - Atlantic Highly Migratory Species; Vessel Monitoring Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-11

    ... Species; Vessel Monitoring Systems AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and... leaving port and at all times away from port. DATES: As of January 1, 2013, all vessels participating in... using VMS units starting two hours prior to leaving port and at all times away from port,...

  7. 19 CFR 18.22 - Procedure at port of exit.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 1 2013-04-01 2013-04-01 false Procedure at port of exit. 18.22 Section 18.22... to Foreign Countries § 18.22 Procedure at port of exit. (a) If transfer is necessary, the procedure shall be as prescribed in § 18.3(d). (b) Upon the arrival at the port of exit of express shipments...

  8. 19 CFR 18.22 - Procedure at port of exit.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Procedure at port of exit. 18.22 Section 18.22... to Foreign Countries § 18.22 Procedure at port of exit. (a) If transfer is necessary, the procedure shall be as prescribed in § 18.3(d). (b) Upon the arrival at the port of exit of express shipments...

  9. 19 CFR 18.22 - Procedure at port of exit.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false Procedure at port of exit. 18.22 Section 18.22... to Foreign Countries § 18.22 Procedure at port of exit. (a) If transfer is necessary, the procedure shall be as prescribed in § 18.3(d). (b) Upon the arrival at the port of exit of express shipments...

  10. 19 CFR 18.22 - Procedure at port of exit.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 1 2014-04-01 2014-04-01 false Procedure at port of exit. 18.22 Section 18.22... to Foreign Countries § 18.22 Procedure at port of exit. (a) If transfer is necessary, the procedure shall be as prescribed in § 18.3(d). (b) Upon the arrival at the port of exit of express shipments...

  11. 19 CFR 18.22 - Procedure at port of exit.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 1 2012-04-01 2012-04-01 false Procedure at port of exit. 18.22 Section 18.22... to Foreign Countries § 18.22 Procedure at port of exit. (a) If transfer is necessary, the procedure shall be as prescribed in § 18.3(d). (b) Upon the arrival at the port of exit of express shipments...

  12. Device having two optical ports for switching applications

    DOEpatents

    Rosen, Ayre; Stabile, Paul J.

    1991-09-24

    A two-sided light-activatable semiconductor switch device having an optical port on each side thereof. The semiconductor device may be a p-i-n diode or of bulk intrinsic material. A two ported p-i-n diode, reverse-biased to "off" by a 1.3 kV dc power supply, conducted 192 A when activated by two 1 kW laser diode arrays, one for each optical port.

  13. Peripheral Venous Access Ports: Outcomes Analysis in 109 Patients

    SciTech Connect

    Bodner, Leonard J.; Nosher, John L.; Patel, Kaushik M.; Siegel, Randall L.; Biswal, Rajiv; Gribbin, Christopher E.; Tokarz, Robert

    2000-03-15

    Purpose: To perform a retrospective outcomes analysis of central venous catheters with peripheral venous access ports, with comparison to published data.Methods: One hundred and twelve central venous catheters with peripherally placed access ports were placed under sonographic guidance in 109 patients over a 4-year period. Ports were placed for the administration of chemotherapy, hyperalimentation, long-term antibiotic therapy, gamma-globulin therapy, and frequent blood sampling. A vein in the upper arm was accessed in each case and the catheter was passed to the superior vena cava or right atrium. Povidone iodine skin preparation was used in the first 65 port insertions. A combination of Iodophor solution and povidone iodine solution was used in the last 47 port insertions. Forty patients received low-dose (1 mg) warfarin sodium beginning the day after port insertion. Three patients received higher doses of warfarin sodium for preexistent venous thrombosis. Catheter performance and complications were assessed and compared with published data.Results: Access into the basilic or brachial veins was obtained in all cases. Ports remained functional for a total of 28,936 patient days. The port functioned in 50% of patients until completion of therapy, or the patient's expiration. Ports were removed prior to completion of therapy in 18% of patients. Eleven patients (9.9% of ports placed) suffered an infectious complication (0.38 per thousand catheter-days)-in nine, at the port implantation site, in two along the catheter. In all 11 instances the port was removed. Port pocket infection in the early postoperative period occurred in three patients (4.7%) receiving a Betadine prep vs two patients (4.2%) receiving a standard O.R. prep. This difference was not statistically significant (p = 0.9). Venous thrombosis occurred in three patients (6.8%) receiving warfarin sodium and in two patients (3%) not receiving warfarin sodium. This difference was not statistically significant

  14. Port-site metastasis after laparoscopic surgery for gastrointestinal cancer.

    PubMed

    Emoto, Shigenobu; Ishigami, Hironori; Yamaguchi, Hironori; Ishihara, Soichiro; Sunami, Eiji; Kitayama, Joji; Watanabe, Toshiaki

    2017-03-01

    Although the incidence of port-site metastasis after laparoscopic surgery for colorectal cancer has markedly decreased since laparoscopic colectomy was first reported in 1991, it still has not reached zero. In colorectal cancer, the safety of laparoscopic surgery, including the low incidence of port-site metastasis, has been proven in large, randomized trials. In gastric cancer, reports of port-site metastasis are extremely rare, but we should await the results of ongoing trials. This brief review summarizes the current knowledge regarding port-site metastasis after laparoscopic surgery for colorectal and gastric cancer.

  15. 18. NORTH TOWER, PORTE COCHERE & FLAG TOWER, LOOKING SOUTHWEST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. NORTH TOWER, PORTE COCHERE & FLAG TOWER, LOOKING SOUTHWEST BY WEST - Smithsonian Institution Building, 1000 Jefferson Drive, between Ninth & Twelfth Streets, Southwest, Washington, District of Columbia, DC

  16. 23. NORTH KEYSTONE OF PORTE COCHERE INSCRIBED 'MDCCCLII.' (1852) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    23. NORTH KEYSTONE OF PORTE COCHERE INSCRIBED 'MDCCCLII.' (1852) - Smithsonian Institution Building, 1000 Jefferson Drive, between Ninth & Twelfth Streets, Southwest, Washington, District of Columbia, DC

  17. 24. WEST KEYSTONE OF PORTE COCHERE INSCRIBED 'J. RENWICK. JR. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    24. WEST KEYSTONE OF PORTE COCHERE INSCRIBED 'J. RENWICK. JR. ARCHITECT.' - Smithsonian Institution Building, 1000 Jefferson Drive, between Ninth & Twelfth Streets, Southwest, Washington, District of Columbia, DC

  18. 25. EAST KEYSTONE OF PORTE COCHERE INSCRIBED 'G. CAMERON. BUILDER.' ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    25. EAST KEYSTONE OF PORTE COCHERE INSCRIBED 'G. CAMERON. BUILDER.' - Smithsonian Institution Building, 1000 Jefferson Drive, between Ninth & Twelfth Streets, Southwest, Washington, District of Columbia, DC

  19. 19. NORTH TOWER, PORTE COCHERE & FLAG TOWER, LOOKING SOUTHWEST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. NORTH TOWER, PORTE COCHERE & FLAG TOWER, LOOKING SOUTHWEST - Smithsonian Institution Building, 1000 Jefferson Drive, between Ninth & Twelfth Streets, Southwest, Washington, District of Columbia, DC

  20. Single incision glove port laparoscopic colorectal cancer resection

    PubMed Central

    Joshi, HMN; Gosselink, MP; Adusumilli, S; Hompes, R; Cunningham, C; Lindsey, I

    2015-01-01

    Introduction The advantages of single port surgery remain controversial. This study was designed to evaluate the safety and feasibility of single incision glove port colon resections using a diathermy hook, reusable ports and standard laparoscopic straight instrumentation. Methods Between June 2012 and February 2014, 70 consecutive patients (30 women) underwent a colonic resection using a wound retractor and glove port. Forty patients underwent a right hemicolectomy through the umbilicus and thirty underwent attempted single port resection via an incision in the right rectus sheath (14 high anterior resection, 13 low anterior resection, 3 abdominoperineal resection). Results Sixty-two procedures (89%) were completed without conversion to open or multiport techniques. Four procedures had to be converted and additional ports were needed in four other patients. The postoperative mortality rate was 0%. Complications occurred in six patients (9%). Two cases were R1 while the remainder were R0 with a median nodal harvest of 20 (range: 9–48). The median length of hospital stay was 5 days (range: 3–25 days) (right hemicolectomy: 5 days (range: 3–12 days), left sided resection: 6 days (range: 4–25 days). At a median follow-up of 14 months, no port site hernias were observed. Conclusions Single incision glove port surgery is an appropriate technique for different colorectal cancer resections and has the advantage of being less expensive than surgery with commercial single incision ports. PMID:26263805

  1. Vapor port and groundwater sampling well

    DOEpatents

    Hubbell, J.M.; Wylie, A.H.

    1996-01-09

    A method and apparatus have been developed for combining groundwater monitoring wells with unsaturated-zone vapor sampling ports. The apparatus allows concurrent monitoring of both the unsaturated and the saturated zone from the same well at contaminated areas. The innovative well design allows for concurrent sampling of groundwater and volatile organic compounds (VOCs) in the vadose (unsaturated) zone from a single well, saving considerable time and money. The sample tubes are banded to the outer well casing during installation of the well casing. 10 figs.

  2. Vapor port and groundwater sampling well

    DOEpatents

    Hubbell, Joel M.; Wylie, Allan H.

    1996-01-01

    A method and apparatus has been developed for combining groundwater monitoring wells with unsaturated-zone vapor sampling ports. The apparatus allows concurrent monitoring of both the unsaturated and the saturated zone from the same well at contaminated areas. The innovative well design allows for concurrent sampling of groundwater and volatile organic compounds (VOCs) in the vadose (unsaturated) zone from a single well, saving considerable time and money. The sample tubes are banded to the outer well casing during installation of the well casing.

  3. Recent sedimentation, northeastern Port Valdez, Alaska

    NASA Astrophysics Data System (ADS)

    Palmer, Harold D.

    1981-09-01

    Sediments accumulating on the northeastern shore of Port Valdez, a fjord leading to Prince William Sound in southern Alaska, are derived from both deltaic and alluvial fan processes. The resulting thick wedge of Recent silts, sands, shells and gravels lies atop irregular ridges of local graywacke bedrock and scattered till deposits. Seismic reflection profiling augmented by soil borings indicates that rapid infilling and upbuilding has occurred at this site. Evidence of slumping suggests general instability of steep submarine slopes in an area characterized by strong earthquakes and large tidal ranges.

  4. Severe Weather Guide, Mediterranean Ports. 20. Livorno

    DTIC Science & Technology

    1988-05-01

    SUBJECT TERMS (Continue on reverse if necessary and identify by block number) Storm haven Mediterranean meteorology Livorno port Mediterranean...Storrvi haven , Livorno iDort, i’ledi terranean meteorology, i^ie d 11 e r’ r’ a n e a n oc e a D O Q r a o !"i v H ( i e IS ) (U) 01 •Naval...Evaluation of the Harbor as a Haven . .3-5 3.3 Currents and Tides 3-6 3.4 Visibility 3-7 3.5 Hazardous Conditions 3-7 3.6 Harbor Protection 3-12

  5. Long-term Outcome of Peripherally Implanted Venous Access Ports in the Forearm in Female Cancer Patients

    SciTech Connect

    Klösges, Laura Meyer, Carsten Boschewitz, Jack Andersson, Magnus; Rudlowski, Christian; Schild, Hans H.; Wilhelm, Kai

    2015-06-15

    PurposeThe aim of this retrospective study was to analyze the long-term outcome of peripherally implanted venous access ports in the forearm at our institution in a female patient collective.MethodsBetween June 2002 and May 2011, a total of 293 female patients with an underlying malignancy had 299 forearm ports implanted in our interventional radiology suite. The mean age of the cohort was 55 ± 12 years (range 26–81 years). The majority of women suffered from breast (59.5 %) or ovarian cancer (28.1 %). Complications were classified as infectious complications, thrombotic and nonthrombotic catheter dysfunction (dislocation of the catheter or port chamber, fracture with/without embolization or kinking of the catheter, port occlusion), and others.ResultsWe analyzed a total of 90,276 catheter days in 248 port systems (47 patients were lost to follow-up). The mean device service interval was 364 days per catheter (range 8–2,132, median 223 days, CI 311–415, SD 404). Sixty-seven early (≤30 days from implantation) or late complications (>30 days) occurred during the observation period (0.74/1,000 catheter days). Common complications were port infection (0.18/1,000 days), thrombotic dysfunction (0.12/1,000 days), and skin dehiscence (0.12/1,000 days). Nonthrombotic dysfunction occurred in a total of 21 cases (0.23/1,000 days) and seemed to cumulate on the venous catheter entry site on the distal upper arm.ConclusionPeripherally implanted venous access ports in the forearm are a safe alternative to chest or upper-arm ports in female oncology patients. Special attention should be paid to signs of skin dehiscence and nonthrombotic dysfunction, especially when used for long-term treatment.

  6. 77 FR 35852 - Safety Zones; Multiple Firework Displays in Captain of the Port, Puget Sound Zone

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-15

    ... Guard is establishing safety zones in Boston Harbor, Holmes Harbor, Port Gardner and Port Townsend for... Gardner near Everett, WA; and Port Townsend July 4th Fireworks on July 4, 2012 in Port Townsend near Point... around position 48 01.048' N, 122 31.866' W. (3) Everett Fourth of July Foundation, Port Gardner,...

  7. 9 CFR 93.303 - Ports designated for the importation of horses.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., Minnesota, is designated as a port of entry for horses from Canada. (c) Mexican border ports. The following land border ports are designated for the entry of horses from Mexico: Brownsville, Hidalgo, Laredo... York. (b) Canadian border ports. (1) The following land border ports are designated as having...

  8. 9 CFR 93.303 - Ports designated for the importation of horses.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., Minnesota, is designated as a port of entry for horses from Canada. (c) Mexican border ports. The following land border ports are designated for the entry of horses from Mexico: Brownsville, Hidalgo, Laredo... York. (b) Canadian border ports. (1) The following land border ports are designated as having...

  9. 9 CFR 93.303 - Ports designated for the importation of horses.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ..., Minnesota, is designated as a port of entry for horses from Canada. (c) Mexican border ports. The following land border ports are designated for the entry of horses from Mexico: Brownsville, Hidalgo, Laredo... York. (b) Canadian border ports. (1) The following land border ports are designated as having...

  10. 9 CFR 93.303 - Ports designated for the importation of horses.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., Minnesota, is designated as a port of entry for horses from Canada. (c) Mexican border ports. The following land border ports are designated for the entry of horses from Mexico: Brownsville, Hidalgo, Laredo... York. (b) Canadian border ports. (1) The following land border ports are designated as having...

  11. Towards Port-Hamiltonian Approach for Modeling and Control of Two-wheeled Wheelchair

    NASA Astrophysics Data System (ADS)

    Aula, A.; Akmeliawati, R.; Ahmad, S.; Altalmas, T. M.; Sidek, S. N.

    2013-12-01

    This paper introduces the modeling and control design of a two-wheeled wheelchair (TWW) based on structure-preserving port-Hamiltonian concept. In this paper, a model of TWW with features, including space-saving, four to two-wheel transformation, and adjustable seat height is proposed to increased mobility and independence of the user. Then, the mathematical model of a TWW in its balanced mode is derived. The model is based on the total energy in the system. The system is divided into subsystems whereby the interconnections which exist are utilized. The nonlinearity of the model is preserved using port-controlled Hamiltonian (PCH) system and made to advantage. The proposed controlled is designed based on the idea of PCH such that the energy balance in the system can be achieved while stabilizing the system.

  12. 9 CFR 93.902 - Ports designated for the importation of live fish, fertilized eggs, and gametes.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EXPORTATION AND IMPORTATION OF ANIMALS.... (3) Mexican border ports. Otay Mesa, CA. (b) Designation of other ports. Other ports may...

  13. Assessing noise sources at synchrotron infrared ports

    PubMed Central

    Lerch, Ph.; Dumas, P.; Schilcher, T.; Nadji, A.; Luedeke, A.; Hubert, N.; Cassinari, L.; Boege, M.; Denard, J.-C.; Stingelin, L.; Nadolski, L.; Garvey, T.; Albert, S.; Gough, Ch.; Quack, M.; Wambach, J.; Dehler, M.; Filhol, J.-M.

    2012-01-01

    Today, the vast majority of electron storage rings delivering synchrotron radiation for general user operation offer a dedicated infrared port. There is growing interest expressed by various scientific communities to exploit the mid-IR emission in microspectroscopy, as well as the far infrared (also called THz) range for spectroscopy. Compared with a thermal (laboratory-based source), IR synchrotron radiation sources offer enhanced brilliance of about two to three orders of magnitude in the mid-IR energy range, and enhanced flux and brilliance in the far-IR energy range. Synchrotron radiation also has a unique combination of a broad wavelength band together with a well defined time structure. Thermal sources (globar, mercury filament) have excellent stability. Because the sampling rate of a typical IR Fourier-transform spectroscopy experiment is in the kHz range (depending on the bandwidth of the detector), instabilities of various origins present in synchrotron radiation sources play a crucial role. Noise recordings at two different IR ports located at the Swiss Light Source and SOLEIL (France), under conditions relevant to real experiments, are discussed. The lowest electron beam fluctuations detectable in IR spectra have been quantified and are shown to be much smaller than what is routinely recorded by beam-position monitors. PMID:22186638

  14. The dominant 55 kDa allergen of the subtropical Bahia grass (Paspalum notatum) pollen is a group 13 pollen allergen, Pas n 13.

    PubMed

    Davies, Janet M; Voskamp, Astrid; Dang, Thanh D; Pettit, Benjamin; Loo, Dorothy; Petersen, Arnd; Hill, Michelle M; Upham, John W; Rolland, Jennifer M; O'Hehir, Robyn E

    2011-03-01

    Bahia grass, Paspalum notatum, is an important pollen allergen source with a long season of pollination and wide distribution in subtropical and temperate regions. We aimed to characterize the 55 kDa allergen of Bahia grass pollen (BaGP) and ascertain its clinical importance. BaGP extract was separated by 2D-PAGE and immunoblotted with serum IgE of a grass pollen-allergic patient. The amino-terminal protein sequence of the predominant allergen isoform at 55 kDa had similarity with the group 13 allergens of Timothy grass and maize pollen, Phl p 13 and Zea m 13. Four sequences obtained by rapid amplification of the allergen cDNA ends represented multiple isoforms of Pas n 13. The predicted full length cDNA for Pas n 13 encoded a 423 amino acid glycoprotein including a signal peptide of 28 residues and with a predicted pI of 7.0. Tandem mass spectrometry of tryptic peptides of 2D gel spots identified peptides specific to the deduced amino acid sequence for each of the four Pas n 13 cDNA, representing 47% of the predicted mature protein sequence of Pas n 13. There was 80.6% and 72.6% amino acid identity with Zea m 13 and Phl p 13, respectively. Reactivity with a Phl p 13-specific monoclonal antibody AF6 supported designation of this allergen as Pas n 13. The allergen was purified from BaGP extract by ammonium sulphate precipitation, hydrophobic interaction and size exclusion chromatography. Purified Pas n 13 reacted with serum IgE of 34 of 71 (48%) grass pollen-allergic patients and specifically inhibited IgE reactivity with the 55 kDa band of BaGP for two grass pollen-allergic donors. Four isoforms of Pas n 13 from pI 6.3-7.8 had IgE-reactivity with grass pollen allergic sera. The allergenic activity of purified Pas n 13 was demonstrated by activation of basophils from whole blood of three grass pollen-allergic donors tested but not control donors. Pas n 13 is thus a clinically relevant pollen allergen of the subtropical Bahia grass likely to be important in eliciting

  15. Crystal structures of the F and pSLT plasmid TraJ N-terminal regions reveal similar homodimeric PAS folds with functional interchangeability.

    PubMed

    Lu, Jun; Wu, Ruiying; Adkins, Joshua N; Joachimiak, Andrzej; Glover, J N Mark

    2014-09-16

    In the F family of conjugative plasmids, TraJ is an essential transcriptional activator of the tra operon that encodes most of the proteins required for conjugation. Here we report for the first time the X-ray crystal structures of the TraJ N-terminal domains from the prototypic F plasmid (TraJF(11-130)) and from the Salmonella virulence plasmid pSLT (TraJpSLT(1-128)). Both structures contain similar Per-ARNT-Sim (PAS) folds, which further homodimerize through the N-terminal helix and the structurally conserved β-sheet of the PAS fold from each protomer. Mutational analysis reveals that the observed dimeric interface is critical for TraJF transcriptional activation, indicating that dimerization of TraJ is required for its in vivo function. TraJ is specific in activating its cognate tra operon promoter; however, heterologous PAS domains from pSLT and R100 TraJ can functionally replace the TraJF PAS domain, suggesting that the allelic specificity of TraJ is solely mediated by the region C-terminal to the PAS domain.

  16. The improved PAS-ELISA method for the diagnosis of the pathogen for banana mosaic heart rot disease.

    PubMed

    Huang, M; Liao, Z

    1996-01-01

    As a fast and practical immunological test, ELISA has been widely applied both in research and diagnosis of plant viruses [1]. In its research utility, PAS-ELISA has been proven as an effective measure to obtain CMV-free micropropagated plantlets. In large-scale micropropagation of banana plantlets, we have been using it in our Quality Control Department to prepare CMV-free and/or TMV-free germplasm. From large-scale testing, we have found that component(s) in banana tissue can cause a nonspecific reaction which severely interferes with the diagnostic results, making the average optical density (OD490nm) value a much higher false positive, leading to an abnormally high percentage loss of the germplasm prepared. The procedure for preparation of the antigen extract from banana tissue has been modified to eliminate the false positive.

  17. PAS-MEDIATED DIMERIZATION OF SOLUBLE GUANYLYL CYCLASE REVEALED BY SIGNAL TRANSDUCTION HISTIDINE KINASE DOMAIN CRYSTAL STRUCTURE

    PubMed Central

    Ma, Xiaolei; Sayed, Nazish; Baskaran, Padmamalini; Beuve, Annie; van den Akker, Focco

    2010-01-01

    Signal transduction histidine kinases (STHK) are key for sensing environmental stresses, crucial for cell survival, and attain their sensing ability using small molecule binding domains. The N-terminal domain in an STHK from Nostoc punctiforme is of unknown function yet is homologous to the central region in soluble guanylyl cyclase (sGC), the main receptor for nitric oxide (NO). This domain is termed H-NOXA (or H-NOBA) since it is often associated with the heme-nitric-oxide/oxygen binding (H-NOX) domain. A structure-function approach was taken to investigate the role of H-NOXA in STHK and sGC. We report the 2.1 Å resolution crystal structure of the dimerized H-NOXA domain of STHK, which reveals a Per-Arnt-Sim (PAS) fold. The H-NOXA monomers dimerize in a parallel arrangement juxtaposing their N-terminal helices and preceding residues. Such PAS-dimerization is similar to that previously observed for EcDOS, AvNifL, and RmFixL. Deletion of 7 N-terminal residues affected dimer organization. Alanine scanning mutagenesis in sGC indicates that the H-NOXA domains of sGC could adopt a similar dimer organization. Although most putative interface mutations did decrease sGCβ1 H-NOXA homodimerization, heterodimerization of full length heterodimeric sGC was mostly unaffected likely due to sGC’s additional dimerization contacts in the coiled-coil and catalytic domains. Exceptions are mutations sGC-α1 F285A and -β1 F217A which each caused a drastic drop in NO stimulated activity and mutations sGCα1 Q368A and -β1 Q309A which resulted in both a complete lack of activity and heterodimerization. Our structural and mutational results provide new insights into sGC and STHK dimerization and overall architecture. PMID:18006497

  18. Pathway-specific regulation revisited: cross-regulation of multiple disparate gene clusters by PAS-LuxR transcriptional regulators.

    PubMed

    Vicente, Cláudia M; Payero, Tamara D; Santos-Aberturas, Javier; Barreales, Eva G; de Pedro, Antonio; Aparicio, Jesús F

    2015-06-01

    PAS-LuxR regulators are highly conserved proteins devoted to the control of antifungal production by binding to operators located in given promoters of polyene biosynthetic genes. The canonical operator of PimM, archetype of this class of regulators, has been used here to search for putative targets of orthologous protein PteF in the genome of Streptomyces avermitilis, finding 97 putative operators outside the pentaene filipin gene cluster (pte). The processes putatively affected included genetic information processing; energy, carbohydrate, and lipid metabolism; DNA replication and repair; morphological differentiation; secondary metabolite biosynthesis; and transcriptional regulation, among others. Seventeen of these operators were selected, and their binding to PimM DNA-binding domain was assessed by electrophoretic mobility shift assays. Strikingly, the protein bound all predicted operators suggesting a direct control over targeted processes. As a proof of concept, we studied the biosynthesis of the ATP-synthase inhibitor oligomycin whose gene cluster included two operators. Regulator mutants showed a severe loss of oligomycin production, whereas gene complementation of the mutant restored phenotype, and gene duplication in the wild-type strain boosted oligomycin production. Comparative gene expression analyses in parental and mutant strains by reverse transcription-quantitative polymerase chain reaction of selected olm genes corroborated production results. These results demonstrate that PteF is able to cross-regulate the biosynthesis of two related secondary metabolites, filipin and oligomycin, but might be extended to all the processes indicated above. This study highlights the complexity of the network of interactions in which PAS-LuxR regulators are involved and opens new possibilities for the manipulation of metabolite production in Streptomycetes.

  19. 32 CFR 806b.11 - When to give Privacy Act Statements (PAS).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... ADMINISTRATION PRIVACY ACT PROGRAM Collecting Personal Information § 806b.11 When to give Privacy Act Statements... information from them that will go in a system of records. Note: Do this regardless of how you collect or... are collecting the information and what you intend to do with it. (3) Routine Uses: A list of...

  20. 9 CFR 98.33 - Ports designated for the importation of certain animal semen.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., Washington. (c) Mexican border ports. The following land border ports are designated as having inspection..., California; Miami, Florida; and Newburgh, New York. (b) Canadian border ports. The following land...