On-board error correction improves IR earth sensor accuracy
NASA Astrophysics Data System (ADS)
Alex, T. K.; Kasturirangan, K.; Shrivastava, S. K.
1989-10-01
Infra-red earth sensors are used in satellites for attitude sensing. Their accuracy is limited by systematic and random errors. The sources of errors in a scanning infra-red earth sensor are analyzed in this paper. The systematic errors arising from seasonal variation of infra-red radiation, oblate shape of the earth, ambient temperature of sensor, changes in scan/spin rates have been analyzed. Simple relations are derived using least square curve fitting for on-board correction of these errors. Random errors arising out of noise from detector and amplifiers, instability of alignment and localized radiance anomalies are analyzed and possible correction methods are suggested. Sun and Moon interference on earth sensor performance has seriously affected a number of missions. The on-board processor detects Sun/Moon interference and corrects the errors on-board. It is possible to obtain eight times improvement in sensing accuracy, which will be comparable with ground based post facto attitude refinement.
Phase-demodulation error of a fiber-optic Fabry-Perot sensor with complex reflection coefficients.
Kilpatrick, J M; MacPherson, W N; Barton, J S; Jones, J D
2000-03-20
The influence of reflector losses attracts little discussion in standard treatments of the Fabry-Perot interferometer yet may be an important factor contributing to errors in phase-stepped demodulation of fiber optic Fabry-Perot (FFP) sensors. We describe a general transfer function for FFP sensors with complex reflection coefficients and estimate systematic phase errors that arise when the asymmetry of the reflected fringe system is neglected, as is common in the literature. The measured asymmetric response of higher-finesse metal-dielectric FFP constructions corroborates a model that predicts systematic phase errors of 0.06 rad in three-step demodulation of a low-finesse FFP sensor (R = 0.05) with internal reflector losses of 25%.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Yu, Jaehyung; Wagner, Lucas K.; Ertekin, Elif, E-mail: ertekin@illinois.edu
2015-12-14
The fixed node diffusion Monte Carlo (DMC) method has attracted interest in recent years as a way to calculate properties of solid materials with high accuracy. However, the framework for the calculation of properties such as total energies, atomization energies, and excited state energies is not yet fully established. Several outstanding questions remain as to the effect of pseudopotentials, the magnitude of the fixed node error, and the size of supercell finite size effects. Here, we consider in detail the semiconductors ZnSe and ZnO and carry out systematic studies to assess the magnitude of the energy differences arising from controlledmore » and uncontrolled approximations in DMC. The former include time step errors and supercell finite size effects for ground and optically excited states, and the latter include pseudopotentials, the pseudopotential localization approximation, and the fixed node approximation. We find that for these compounds, the errors can be controlled to good precision using modern computational resources and that quantum Monte Carlo calculations using Dirac-Fock pseudopotentials can offer good estimates of both cohesive energy and the gap of these systems. We do however observe differences in calculated optical gaps that arise when different pseudopotentials are used.« less
Global Warming Estimation from MSU
NASA Technical Reports Server (NTRS)
Prabhakara, C.; Iacovazzi, Robert, Jr.
1999-01-01
In this study, we have developed time series of global temperature from 1980-97 based on the Microwave Sounding Unit (MSU) Ch 2 (53.74 GHz) observations taken from polar-orbiting NOAA operational satellites. In order to create these time series, systematic errors (approx. 0.1 K) in the Ch 2 data arising from inter-satellite differences are removed objectively. On the other hand, smaller systematic errors (approx. 0.03 K) in the data due to orbital drift of each satellite cannot be removed objectively. Such errors are expected to remain in the time series and leave an uncertainty in the inferred global temperature trend. With the help of a statistical method, the error in the MSU inferred global temperature trend resulting from orbital drifts and residual inter-satellite differences of all satellites is estimated to be 0.06 K decade. Incorporating this error, our analysis shows that the global temperature increased at a rate of 0.13 +/- 0.06 K decade during 1980-97.
Global Warming Estimation from MSU
NASA Technical Reports Server (NTRS)
Prabhakara, C.; Iacovazzi, Robert; Yoo, Jung-Moon
1998-01-01
Microwave Sounding Unit (MSU) radiometer observations in Ch 2 (53.74 GHz) from sequential, sun-synchronous, polar-orbiting NOAA satellites contain small systematic errors. Some of these errors are time-dependent and some are time-independent. Small errors in Ch 2 data of successive satellites arise from calibration differences. Also, successive NOAA satellites tend to have different Local Equatorial Crossing Times (LECT), which introduce differences in Ch 2 data due to the diurnal cycle. These two sources of systematic error are largely time independent. However, because of atmospheric drag, there can be a drift in the LECT of a given satellite, which introduces time-dependent systematic errors. One of these errors is due to the progressive chance in the diurnal cycle and the other is due to associated chances in instrument heating by the sun. In order to infer global temperature trend from the these MSU data, we have eliminated explicitly the time-independent systematic errors. Both of the time-dependent errors cannot be assessed from each satellite. For this reason, their cumulative effect on the global temperature trend is evaluated implicitly. Christy et al. (1998) (CSL). based on their method of analysis of the MSU Ch 2 data, infer a global temperature cooling trend (-0.046 K per decade) from 1979 to 1997, although their near nadir measurements yield near zero trend (0.003 K/decade). Utilising an independent method of analysis, we infer global temperature warmed by 0.12 +/- 0.06 C per decade from the observations of the MSU Ch 2 during the period 1980 to 1997.
Focusing cosmic telescopes: systematics of strong lens modeling
NASA Astrophysics Data System (ADS)
Johnson, Traci Lin; Sharon, Keren q.
2018-01-01
The use of strong gravitational lensing by galaxy clusters has become a popular method for studying the high redshift universe. While diverse in computational methods, lens modeling techniques have grasped the means for determining statistical errors on cluster masses and magnifications. However, the systematic errors have yet to be quantified, arising from the number of constraints, availablity of spectroscopic redshifts, and various types of image configurations. I will be presenting my dissertation work on quantifying systematic errors in parametric strong lensing techniques. I have participated in the Hubble Frontier Fields lens model comparison project, using simulated clusters to compare the accuracy of various modeling techniques. I have extended this project to understanding how changing the quantity of constraints affects the mass and magnification. I will also present my recent work extending these studies to clusters in the Outer Rim Simulation. These clusters are typical of the clusters found in wide-field surveys, in mass and lensing cross-section. These clusters have fewer constraints than the HFF clusters and thus, are more susceptible to systematic errors. With the wealth of strong lensing clusters discovered in surveys such as SDSS, SPT, DES, and in the future, LSST, this work will be influential in guiding the lens modeling efforts and follow-up spectroscopic campaigns.
Error and Uncertainty Quantification in the Numerical Simulation of Complex Fluid Flows
NASA Technical Reports Server (NTRS)
Barth, Timothy J.
2010-01-01
The failure of numerical simulation to predict physical reality is often a direct consequence of the compounding effects of numerical error arising from finite-dimensional approximation and physical model uncertainty resulting from inexact knowledge and/or statistical representation. In this topical lecture, we briefly review systematic theories for quantifying numerical errors and restricted forms of model uncertainty occurring in simulations of fluid flow. A goal of this lecture is to elucidate both positive and negative aspects of applying these theories to practical fluid flow problems. Finite-element and finite-volume calculations of subsonic and hypersonic fluid flow are presented to contrast the differing roles of numerical error and model uncertainty. for these problems.
Improved arrayed-waveguide-grating layout avoiding systematic phase errors.
Ismail, Nur; Sun, Fei; Sengo, Gabriel; Wörhoff, Kerstin; Driessen, Alfred; de Ridder, René M; Pollnau, Markus
2011-04-25
We present a detailed description of an improved arrayed-waveguide-grating (AWG) layout for both, low and high diffraction orders. The novel layout presents identical bends across the entire array; in this way systematic phase errors arising from different bends that are inherent to conventional AWG designs are completely eliminated. In addition, for high-order AWGs our design results in more than 50% reduction of the occupied area on the wafer. We present an experimental characterization of a low-order device fabricated according to this geometry. The device has a resolution of 5.5 nm, low intrinsic losses (< 2 dB) in the wavelength region of interest for the application, and is polarization insensitive over a wide spectral range of 215 nm.
NASA Astrophysics Data System (ADS)
Nsamba, B.; Campante, T. L.; Monteiro, M. J. P. F. G.; Cunha, M. S.; Rendle, B. M.; Reese, D. R.; Verma, K.
2018-04-01
Asteroseismic forward modelling techniques are being used to determine fundamental properties (e.g. mass, radius, and age) of solar-type stars. The need to take into account all possible sources of error is of paramount importance towards a robust determination of stellar properties. We present a study of 34 solar-type stars for which high signal-to-noise asteroseismic data is available from multi-year Kepler photometry. We explore the internal systematics on the stellar properties, that is, associated with the uncertainty in the input physics used to construct the stellar models. In particular, we explore the systematics arising from: (i) the inclusion of the diffusion of helium and heavy elements; and (ii) the uncertainty in solar metallicity mixture. We also assess the systematics arising from (iii) different surface correction methods used in optimisation/fitting procedures. The systematics arising from comparing results of models with and without diffusion are found to be 0.5%, 0.8%, 2.1%, and 16% in mean density, radius, mass, and age, respectively. The internal systematics in age are significantly larger than the statistical uncertainties. We find the internal systematics resulting from the uncertainty in solar metallicity mixture to be 0.7% in mean density, 0.5% in radius, 1.4% in mass, and 6.7% in age. The surface correction method by Sonoi et al. and Ball & Gizon's two-term correction produce the lowest internal systematics among the different correction methods, namely, ˜1%, ˜1%, ˜2%, and ˜8% in mean density, radius, mass, and age, respectively. Stellar masses obtained using the surface correction methods by Kjeldsen et al. and Ball & Gizon's one-term correction are systematically higher than those obtained using frequency ratios.
Errors in retarding potential analyzers caused by nonuniformity of the grid-plane potential.
NASA Technical Reports Server (NTRS)
Hanson, W. B.; Frame, D. R.; Midgley, J. E.
1972-01-01
One aspect of the degradation in performance of retarding potential analyzers caused by potential depressions in the retarding grid is quantitatively estimated from laboratory measurements and theoretical calculations. A simple expression is obtained that permits the use of laboratory measurements of grid properties to make first-order corrections to flight data. Systematic positive errors in ion temperature of approximately 16% for the Ogo 4 instrument and 3% for the Ogo 6 instrument are deduced. The effects of the transverse electric fields arising from the grid potential depressions are not treated.
A probabilistic approach to remote compositional analysis of planetary surfaces
Lapotre, Mathieu G.A.; Ehlmann, Bethany L.; Minson, Sarah E.
2017-01-01
Reflected light from planetary surfaces provides information, including mineral/ice compositions and grain sizes, by study of albedo and absorption features as a function of wavelength. However, deconvolving the compositional signal in spectra is complicated by the nonuniqueness of the inverse problem. Trade-offs between mineral abundances and grain sizes in setting reflectance, instrument noise, and systematic errors in the forward model are potential sources of uncertainty, which are often unquantified. Here we adopt a Bayesian implementation of the Hapke model to determine sets of acceptable-fit mineral assemblages, as opposed to single best fit solutions. We quantify errors and uncertainties in mineral abundances and grain sizes that arise from instrument noise, compositional end members, optical constants, and systematic forward model errors for two suites of ternary mixtures (olivine-enstatite-anorthite and olivine-nontronite-basaltic glass) in a series of six experiments in the visible-shortwave infrared (VSWIR) wavelength range. We show that grain sizes are generally poorly constrained from VSWIR spectroscopy. Abundance and grain size trade-offs lead to typical abundance errors of ≤1 wt % (occasionally up to ~5 wt %), while ~3% noise in the data increases errors by up to ~2 wt %. Systematic errors further increase inaccuracies by a factor of 4. Finally, phases with low spectral contrast or inaccurate optical constants can further increase errors. Overall, typical errors in abundance are <10%, but sometimes significantly increase for specific mixtures, prone to abundance/grain-size trade-offs that lead to high unmixing uncertainties. These results highlight the need for probabilistic approaches to remote determination of planetary surface composition.
A review of multimodel superensemble forecasting for weather, seasonal climate, and hurricanes
NASA Astrophysics Data System (ADS)
Krishnamurti, T. N.; Kumar, V.; Simon, A.; Bhardwaj, A.; Ghosh, T.; Ross, R.
2016-06-01
This review provides a summary of work in the area of ensemble forecasts for weather, climate, oceans, and hurricanes. This includes a combination of multiple forecast model results that does not dwell on the ensemble mean but uses a unique collective bias reduction procedure. A theoretical framework for this procedure is provided, utilizing a suite of models that is constructed from the well-known Lorenz low-order nonlinear system. A tutorial that includes a walk-through table and illustrates the inner workings of the multimodel superensemble's principle is provided. Systematic errors in a single deterministic model arise from a host of features that range from the model's initial state (data assimilation), resolution, representation of physics, dynamics, and ocean processes, local aspects of orography, water bodies, and details of the land surface. Models, in their diversity of representation of such features, end up leaving unique signatures of systematic errors. The multimodel superensemble utilizes as many as 10 million weights to take into account the bias errors arising from these diverse features of multimodels. The design of a single deterministic forecast models that utilizes multiple features from the use of the large volume of weights is provided here. This has led to a better understanding of the error growths and the collective bias reductions for several of the physical parameterizations within diverse models, such as cumulus convection, planetary boundary layer physics, and radiative transfer. A number of examples for weather, seasonal climate, hurricanes and sub surface oceanic forecast skills of member models, the ensemble mean, and the superensemble are provided.
Tuning a climate model using nudging to reanalysis.
NASA Astrophysics Data System (ADS)
Cheedela, S. K.; Mapes, B. E.
2014-12-01
Tuning a atmospheric general circulation model involves a daunting task of adjusting non-observable parameters to adjust the mean climate. These parameters arise from necessity to describe unresolved flow through parametrizations. Tuning a climate model is often done with certain set of priorities, such as global mean temperature, net top of the atmosphere radiation. These priorities are hard enough to reach let alone reducing systematic biases in the models. The goal of currently study is to explore alternate ways to tune a climate model to reduce some systematic biases that can be used in synergy with existing efforts. Nudging a climate model to a known state is a poor man's inverse of tuning process described above. Our approach involves nudging the atmospheric model to state of art reanalysis fields thereby providing a balanced state with respect to the global mean temperature and winds. The tendencies derived from nudging are negative of errors from physical parametrizations as the errors from dynamical core would be small. Patterns of nudging are compared to the patterns of different physical parametrizations to decipher the cause for certain biases in relation to tuning parameters. This approach might also help in understanding certain compensating errors that arise from tuning process. ECHAM6 is a comprehensive general model, also used in recent Coupled Model Intercomparision Project(CMIP5). The approach used to tune it and effect of certain parameters that effect its mean climate are reported clearly, hence it serves as a benchmark for our approach. Our planned experiments include nudging ECHAM6 atmospheric model to European Center Reanalysis (ERA-Interim) and reanalysis from National Center for Environmental Prediction (NCEP) and decipher choice of certain parameters that lead to systematic biases in its simulations. Of particular interest are reducing long standing biases related to simulation of Asian summer monsoon.
NASA Technical Reports Server (NTRS)
Beck, S. M.
1975-01-01
A mobile self-contained Faraday cup system for beam current measurments of nominal 600 MeV protons was designed, constructed, and used at the NASA Space Radiation Effects Laboratory. The cup is of reentrant design with a length of 106.7 cm and an outside diameter of 20.32 cm. The inner diameter is 15.24 cm and the base thickness is 30.48 cm. The primary absorber is commercially available lead hermetically sealed in a 0.32-cm-thick copper jacket. Several possible systematic errors in using the cup are evaluated. The largest source of error arises from high-energy electrons which are ejected from the entrance window and enter the cup. A total systematic error of -0.83 percent is calculated to be the decrease from the true current value. From data obtained in calibrating helium-filled ion chambers with the Faraday cup, the mean energy required to produce one ion pair in helium is found to be 30.76 + or - 0.95 eV for nominal 600 MeV protons. This value agrees well, within experimental error, with reported values of 29.9 eV and 30.2 eV.
NASA Technical Reports Server (NTRS)
Pavlis, Nikolaos K.
1991-01-01
An error analysis study was conducted in order to assess the current accuracies and the future anticipated improvements in the estimation of geopotential differences over intercontinental locations. An observation/estimation scheme was proposed and studied, whereby gravity disturbance measurements on the Earth's surface, in caps surrounding the estimation points, are combined with corresponding data in caps directly over these points at the altitude of a low orbiting satellite, for the estimation of the geopotential difference between the terrestrial stations. The mathematical modeling required to relate the primary observables to the parameters to be estimated, was studied for the terrestrial data and the data at altitude. Emphasis was placed on the examination of systematic effects and on the corresponding reductions that need to be applied to the measurements to avoid systematic errors. The error estimation for the geopotential differences was performed using both truncation theory and least squares collocation with ring averages, in case observations on the Earth's surface only are used. The error analysis indicated that with the currently available global geopotential model OSU89B and with gravity disturbance data in 2 deg caps surrounding the estimation points, the error of the geopotential difference arising from errors in the reference model and the cap data is about 23 kgal cm, for 30 deg station separation.
SU-E-J-117: Verification Method for the Detection Accuracy of Automatic Winston Lutz Test
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tang, A; Chan, K; Fee, F
2014-06-01
Purpose: Winston Lutz test (WLT) has been a standard QA procedure performed prior to SRS treatment, to verify the mechanical iso-center setup accuracy upon different Gantry/Couch movements. Several detection algorithms exist,for analyzing the ball-radiation field alignment automatically. However, the accuracy of these algorithms have not been fully addressed. Here, we reveal the possible errors arise from each step in WLT, and verify the software detection accuracy with the Rectilinear Phantom Pointer (RLPP), a tool commonly used for aligning treatment plan coordinate with mechanical iso-center. Methods: WLT was performed with the radio-opaque ball mounted on a MIS and irradiated onto EDR2more » films. The films were scanned and processed with an in-house Matlab program for automatic iso-center detection. Tests were also performed to identify the errors arise from setup, film development and scanning process. The radioopaque ball was then mounted onto the RLPP, and offset laterally and longitudinally in 7 known positions ( 0, ±0.2, ±0.5, ±0.8 mm) manually for irradiations. The gantry and couch was set to zero degree for all irradiation. The same scanned images were processed repeatedly to check the repeatability of the software. Results: Miminal discrepancies (mean=0.05mm) were detected with 2 films overlapped and irradiated but developed separately. This reveals the error arise from film processor and scanner alone. Maximum setup errors were found to be around 0.2mm, by analyzing data collected from 10 irradiations over 2 months. For the known shift introduced using the RLPP, the results agree with the manual offset, and fit linearly (R{sup 2}>0.99) when plotted relative to the first ball with zero shift. Conclusion: We systematically reveal the possible errors arise from each step in WLT, and introduce a simple method to verify the detection accuracy of our in-house software using a clinically available tool.« less
An Examination of the Spatial Distribution of Carbon Dioxide and Systematic Errors
NASA Technical Reports Server (NTRS)
Coffey, Brennan; Gunson, Mike; Frankenberg, Christian; Osterman, Greg
2011-01-01
The industrial period and modern age is characterized by combustion of coal, oil, and natural gas for primary energy and transportation leading to rising levels of atmospheric of CO2. This increase, which is being carefully measured, has ramifications throughout the biological world. Through remote sensing, it is possible to measure how many molecules of CO2 lie in a defined column of air. However, other gases and particles are present in the atmosphere, such as aerosols and water, which make such measurements more complicated1. Understanding the detailed geometry and path length of the observation is vital to computing the concentration of CO2. Comparing these satellite readings with ground-truth data (TCCON) the systematic errors arising from these sources can be assessed. Once the error is understood, it can be scaled for in the retrieval algorithms to create a set of data, which is closer to the TCCON measurements1. Using this process, the algorithms are being developed to reduce bias, within.1% worldwide of the true value. At this stage, the accuracy is within 1%, but through correcting small errors contained in the algorithms, such as accounting for the scattering of sunlight, the desired accuracy can be achieved.
NASA Astrophysics Data System (ADS)
Bhargava, K.; Kalnay, E.; Carton, J.; Yang, F.
2017-12-01
Systematic forecast errors, arising from model deficiencies, form a significant portion of the total forecast error in weather prediction models like the Global Forecast System (GFS). While much effort has been expended to improve models, substantial model error remains. The aim here is to (i) estimate the model deficiencies in the GFS that lead to systematic forecast errors, (ii) implement an online correction (i.e., within the model) scheme to correct GFS following the methodology of Danforth et al. [2007] and Danforth and Kalnay [2008, GRL]. Analysis Increments represent the corrections that new observations make on, in this case, the 6-hr forecast in the analysis cycle. Model bias corrections are estimated from the time average of the analysis increments divided by 6-hr, assuming that initial model errors grow linearly and first ignoring the impact of observation bias. During 2012-2016, seasonal means of the 6-hr model bias are generally robust despite changes in model resolution and data assimilation systems, and their broad continental scales explain their insensitivity to model resolution. The daily bias dominates the sub-monthly analysis increments and consists primarily of diurnal and semidiurnal components, also requiring a low dimensional correction. Analysis increments in 2015 and 2016 are reduced over oceans, which is attributed to improvements in the specification of the SSTs. These results encourage application of online correction, as suggested by Danforth and Kalnay, for mean, seasonal and diurnal and semidiurnal model biases in GFS to reduce both systematic and random errors. As the error growth in the short-term is still linear, estimated model bias corrections can be added as a forcing term in the model tendency equation to correct online. Preliminary experiments with GFS, correcting temperature and specific humidity online show reduction in model bias in 6-hr forecast. This approach can then be used to guide and optimize the design of sub-grid scale physical parameterizations, more accurate discretization of the model dynamics, boundary conditions, radiative transfer codes, and other potential model improvements which can then replace the empirical correction scheme. The analysis increments also provide guidance in testing new physical parameterizations.
Systematic Errors in Peptide and Protein Identification and Quantification by Modified Peptides*
Bogdanow, Boris; Zauber, Henrik; Selbach, Matthias
2016-01-01
The principle of shotgun proteomics is to use peptide mass spectra in order to identify corresponding sequences in a protein database. The quality of peptide and protein identification and quantification critically depends on the sensitivity and specificity of this assignment process. Many peptides in proteomic samples carry biochemical modifications, and a large fraction of unassigned spectra arise from modified peptides. Spectra derived from modified peptides can erroneously be assigned to wrong amino acid sequences. However, the impact of this problem on proteomic data has not yet been investigated systematically. Here we use combinations of different database searches to show that modified peptides can be responsible for 20–50% of false positive identifications in deep proteomic data sets. These false positive hits are particularly problematic as they have significantly higher scores and higher intensities than other false positive matches. Furthermore, these wrong peptide assignments lead to hundreds of false protein identifications and systematic biases in protein quantification. We devise a “cleaned search” strategy to address this problem and show that this considerably improves the sensitivity and specificity of proteomic data. In summary, we show that modified peptides cause systematic errors in peptide and protein identification and quantification and should therefore be considered to further improve the quality of proteomic data annotation. PMID:27215553
Heritability analyses of IQ scores: science or numerology?
Layzer, D
1974-03-29
Estimates of IQ heritability are subject to a variety of systematic errors. The IQ scores themselves contain uncontrollable, systematic errors of unknown magnitude. These arise because IQ scores, unlike conventional physical and biological measurements, have a purely instrumental definition. The effects of these errors are apparent in the very large discrepancies among IQ correlations measured by different investigators. Genotype-environment correlations, whose effects can sometimes be minimized, if not wholly eliminated, in experiments with plants and animals, are nearly always important in human populations. The absence of significant effects arising from genotype-environment correlations is a necessary condition for the applicability of conventional heritability analysis to phenotypically plastic traits. When this condition fails, no quantitative inferences about heritability can be drawn from measured phenotypic variances and covariances, except under special conditions that are unlikely to be satisfied by phenotypically plastic traits in human populations. Inadequate understanding of the precise environmental factors relevant to the development of specific behavioral traits is an important source of systematic errors, as is the inability to allow adequately for the effects of assortative mating and gene-gene interaction. Systematic cultural differences and differences in psychological environment among races and among sociocco-nomic groups vitiate any attempt to draw from IQ data meaningful inferences about genetic differences. Estimates based on phenotypic correlations between separated monozygotic twins-usually considered to be the most reliable kind of estimates-are vitiated by systematic errors inherent in IQ tests, by the presence of genotype-environment correlation, and by the lack of detailed understanding of environmental factors relevant to the development of behavioral traits. Other kinds of estimates are beset, in addition, by systematic errors arising from incomplete allowance for the effects of assortative mating and from gene-gene interactions. The only potentially useful data are phenotypic correlations between unrelated foster children reared together, which could, in principle, yield lower limits for e(2). Available data indicate that, for unrelated foster children reared together, the broad heritability (h(2)) may lie between 0.0 and 0.5. This estimate does not apply to populations composed of children reared by their biological parents or by near relatives. For such populations the heritability of IQ remains undefined. The only data that might yield meaningful estimates ot narrow heritability are phenotypic correlations between half-sibs reared in statistically independent environments. No useful data of this kind are available. Intervention studies like Heber's Milwaukee Project afford an alternative and comparatively direct way of studying the plasticity of cognitive and other behavioral traits in human populations. Results obtained so far strongly suggest that the development of cognitive skills is highly sensitive to variations in environmental factors. These conclusions have three obvious implications for the broader issues mentioned at the beginning of this article. 1) Published analyses of IQ data provide no support whatever for Jensen's thesis that inequalities in cognitive performance are due largely to genetic differences. As Lewontin (8) has clearly shown, the value of the broad heritability of IQ is in any case only marginally relevant to this question. I have argued that conventional estimates of the broad heritability of IQ are invalid and that the only data on which potentially valid estimates might be based are consistent with a broad heritability of less than 0.5. On the other hand, intervention studies, if their findings prove to be replicable, would directly establish that, under suitable conditions, the offspring of parents whose cognitive skills are so poorly developed as to exclude them from all but the most menial occupations can achieve what are regarded as distinctly high levels of cognitive performance. Thus, despite the fact that children differ suibstantially in cognitive aptitudes and appetites, and despite the very high probability that these differences have a substantial genetic component, available scientific evidence strongly suggests that environmental factors are responsible for the failure of children not suffering from specific neurological disorders to achieve adequate levels of cognitive performance. 2) Under prevailing social conditions, no valid inferences can be drawn from IQ data concerning systematic genetic differences among races or socioeconomic groups. Research along present lines directed toward this end-whatever its ethical status-is scientifically worthless. 3) Since there are no suitable data for estimating the narrow heritability of IQ, it seems pointless to speculate about the prospects for a hereditary meritocracy based on IQ.
Effect of Processing Conditions on the Anelastic Behavior of Plasma Sprayed Thermal Barrier Coatings
NASA Astrophysics Data System (ADS)
Viswanathan, Vaishak
2011-12-01
Plasma sprayed ceramic materials contain an assortment of micro-structural defects, including pores, cracks, and interfaces arising from the droplet based assemblage of the spray deposition technique. The defective architecture of the deposits introduces a novel "anelastic" response in the coatings comprising of their non-linear and hysteretic stress-strain relationship under mechanical loading. It has been established that this anelasticity can be attributed to the relative movement of the embedded defects under varying stresses. While the non-linear response of the coatings arises from the opening/closure of defects, hysteresis is produced by the frictional sliding among defect surfaces. Recent studies have indicated that anelastic behavior of coatings can be a unique descriptor of their mechanical behavior and related to the defect configuration. In this dissertation, a multi-variable study employing systematic processing strategies was conducted to augment the understanding on various aspects of the reported anelastic behavior. A bi-layer curvature measurement technique was adapted to measure the anelastic properties of plasma sprayed ceramic. The quantification of anelastic parameters was done using a non-linear model proposed by Nakamura et.al. An error analysis was conducted on the technique to know the available margins for both experimental as well as computational errors. The error analysis was extended to evaluate its sensitivity towards different coating microstructure. For this purpose, three coatings with significantly different microstructures were fabricated via tuning of process parameters. Later the three coatings were also subjected to different strain ranges systematically, in order to understand the origin and evolution of anelasticity on different microstructures. The last segment of this thesis attempts to capture the intricacies on the processing front and tries to evaluate and establish a correlation between them and the anelastic parameters.
Phonological and Motor Errors in Individuals with Acquired Sound Production Impairment
ERIC Educational Resources Information Center
Buchwald, Adam; Miozzo, Michele
2012-01-01
Purpose: This study aimed to compare sound production errors arising due to phonological processing impairment with errors arising due to motor speech impairment. Method: Two speakers with similar clinical profiles who produced similar consonant cluster simplification errors were examined using a repetition task. We compared both overall accuracy…
Attitude errors arising from antenna/satellite altitude errors - Recognition and reduction
NASA Technical Reports Server (NTRS)
Godbey, T. W.; Lambert, R.; Milano, G.
1972-01-01
A review is presented of the three basic types of pulsed radar altimeter designs, as well as the source and form of altitude bias errors arising from antenna/satellite attitude errors in each design type. A quantitative comparison of the three systems was also made.
A review of uncertainty in in situ measurements and data sets of sea surface temperature
NASA Astrophysics Data System (ADS)
Kennedy, John J.
2014-03-01
Archives of in situ sea surface temperature (SST) measurements extend back more than 160 years. Quality of the measurements is variable, and the area of the oceans they sample is limited, especially early in the record and during the two world wars. Measurements of SST and the gridded data sets that are based on them are used in many applications so understanding and estimating the uncertainties are vital. The aim of this review is to give an overview of the various components that contribute to the overall uncertainty of SST measurements made in situ and of the data sets that are derived from them. In doing so, it also aims to identify current gaps in understanding. Uncertainties arise at the level of individual measurements with both systematic and random effects and, although these have been extensively studied, refinement of the error models continues. Recent improvements have been made in the understanding of the pervasive systematic errors that affect the assessment of long-term trends and variability. However, the adjustments applied to minimize these systematic errors are uncertain and these uncertainties are higher before the 1970s and particularly large in the period surrounding the Second World War owing to a lack of reliable metadata. The uncertainties associated with the choice of statistical methods used to create globally complete SST data sets have been explored using different analysis techniques, but they do not incorporate the latest understanding of measurement errors, and they want for a fair benchmark against which their skill can be objectively assessed. These problems can be addressed by the creation of new end-to-end SST analyses and by the recovery and digitization of data and metadata from ship log books and other contemporary literature.
Global Warming Estimation from MSU: Correction for Drift and Calibration Errors
NASA Technical Reports Server (NTRS)
Prabhakara, C.; Iacovazzi, R., Jr.; Yoo, J.-M.; Einaudi, Franco (Technical Monitor)
2000-01-01
Microwave Sounding Unit (MSU) radiometer observations in Ch 2 (53.74 GHz), made in the nadir direction from sequential, sun-synchronous, polar-orbiting NOAA morning satellites (NOAA 6, 10 and 12 that have about 7am/7pm orbital geometry) and afternoon satellites (NOAA 7, 9, 11 and 14 that have about 2am/2pm orbital geometry) are analyzed in this study to derive global temperature trend from 1980 to 1998. In order to remove the discontinuities between the data of the successive satellites and to get a continuous time series, first we have used shortest possible time record of each satellite. In this way we get a preliminary estimate of the global temperature trend of 0.21 K/decade. However, this estimate is affected by systematic time-dependent errors. One such error is the instrument calibration error. This error can be inferred whenever there are overlapping measurements made by two satellites over an extended period of time. From the available successive satellite data we have taken the longest possible time record of each satellite to form the time series during the period 1980 to 1998 to this error. We find we can decrease the global temperature trend by about 0.07 K/decade. In addition there are systematic time dependent errors present in the data that are introduced by the drift in the satellite orbital geometry arises from the diurnal cycle in temperature which is the drift related change in the calibration of the MSU. In order to analyze the nature of these drift related errors the multi-satellite Ch 2 data set is partitioned into am and pm subsets to create two independent time series. The error can be assessed in the am and pm data of Ch 2 on land and can be eliminated. Observations made in the MSU Ch 1 (50.3 GHz) support this approach. The error is obvious only in the difference between the pm and am observations of Ch 2 over the ocean. We have followed two different paths to assess the impact of the errors on the global temperature trend. In one path the entire error is placed in the am data while in the other it is placed in the pm data. Global temperature trend is increased or decreased by about 0.03 K/decade depending upon this placement. Taking into account all random errors and systematic errors our analysis of MSU observations leads us to conclude that a conservative estimate of the global warming is 0. 11 (+-) 0.04 K/decade during 1980 to 1998.
NASA Astrophysics Data System (ADS)
Altuntaş, Emine; Ammon, Jeffrey; Cahn, Sidney B.; DeMille, David
2018-04-01
Nuclear-spin-dependent parity violation (NSD-PV) effects in atoms and molecules arise from Z0 boson exchange between electrons and the nucleus and from the magnetic interaction between electrons and the parity-violating nuclear anapole moment. It has been proposed to study NSD-PV effects using an enhancement of the observable effect in diatomic molecules [D. DeMille et al., Phys. Rev. Lett. 100, 023003 (2008), 10.1103/PhysRevLett.100.023003]. Here we demonstrate highly sensitive measurements of this type, using the test system 138Ba19F. We show that systematic errors associated with our technique can be suppressed to at least the level of the present statistical sensitivity. With ˜170 h of data, we measure the matrix element W of the NSD-PV interaction with uncertainty δ W /(2 π )<0.7 Hz for each of two configurations where W must have different signs. This sensitivity would be sufficient to measure NSD-PV effects of the size anticipated across a wide range of nuclei.
Shear Recovery Accuracy in Weak-Lensing Analysis with the Elliptical Gauss-Laguerre Method
NASA Astrophysics Data System (ADS)
Nakajima, Reiko; Bernstein, Gary
2007-04-01
We implement the elliptical Gauss-Laguerre (EGL) galaxy-shape measurement method proposed by Bernstein & Jarvis and quantify the shear recovery accuracy in weak-lensing analysis. This method uses a deconvolution fitting scheme to remove the effects of the point-spread function (PSF). The test simulates >107 noisy galaxy images convolved with anisotropic PSFs and attempts to recover an input shear. The tests are designed to be immune to statistical (random) distributions of shapes, selection biases, and crowding, in order to test more rigorously the effects of detection significance (signal-to-noise ratio [S/N]), PSF, and galaxy resolution. The systematic error in shear recovery is divided into two classes, calibration (multiplicative) and additive, with the latter arising from PSF anisotropy. At S/N > 50, the deconvolution method measures the galaxy shape and input shear to ~1% multiplicative accuracy and suppresses >99% of the PSF anisotropy. These systematic errors increase to ~4% for the worst conditions, with poorly resolved galaxies at S/N simeq 20. The EGL weak-lensing analysis has the best demonstrated accuracy to date, sufficient for the next generation of weak-lensing surveys.
Sampling problems: The small scale structure of precipitation
NASA Technical Reports Server (NTRS)
Crane, R. K.
1981-01-01
The quantitative measurement of precipitation characteristics for any area on the surface of the Earth is not an easy task. Precipitation is rather variable in both space and time, and the distribution of surface rainfall data given location typically is substantially skewed. There are a number of precipitation process at work in the atmosphere, and few of them are well understood. The formal theory on sampling and estimating precipitation appears considerably deficient. Little systematic attention is given to nonsampling errors that always arise in utilizing any measurement system. Although the precipitation measurement problem is an old one, it continues to be one that is in need of systematic and careful attention. A brief history of the presently competing measurement technologies should aid us in understanding the problem inherent in this measurement task.
NASA Astrophysics Data System (ADS)
Nsamba, B.; Campante, T. L.; Monteiro, M. J. P. F. G.; Cunha, M. S.; Rendle, B. M.; Reese, D. R.; Verma, K.
2018-07-01
Asteroseismic forward modelling techniques are being used to determine fundamental properties (e.g. mass, radius, and age) of solar-type stars. The need to take into account all possible sources of error is of paramount importance towards a robust determination of stellar properties. We present a study of 34 solar-type stars for which high signal-to-noise asteroseismic data are available from multiyear Kepler photometry. We explore the internal systematics on the stellar properties, that is associated with the uncertainty in the input physics used to construct the stellar models. In particular, we explore the systematics arising from (i) the inclusion of the diffusion of helium and heavy elements; (ii) the uncertainty in solar metallicity mixture; and (iii) different surface correction methods used in optimization/fitting procedures. The systematics arising from comparing results of models with and without diffusion are found to be 0.5 per cent, 0.8 per cent, 2.1 per cent, and 16 per cent in mean density, radius, mass, and age, respectively. The internal systematics in age are significantly larger than the statistical uncertainties. We find the internal systematics resulting from the uncertainty in solar metallicity mixture to be 0.7 per cent in mean density, 0.5 per cent in radius, 1.4 per cent in mass, and 6.7 per cent in age. The surface correction method by Sonoi et al. and Ball & Gizon's two-term correction produce the lowest internal systematics among the different correction methods, namely, ˜1 per cent, ˜1 per cent, ˜2 per cent, and ˜8 per cent in mean density, radius, mass, and age, respectively. Stellar masses obtained using the surface correction methods by Kjeldsen et al. and Ball & Gizon's one-term correction are systematically higher than those obtained using frequency ratios.
Laboratory issues: use of nutritional biomarkers.
Blanck, Heidi Michels; Bowman, Barbara A; Cooper, Gerald R; Myers, Gary L; Miller, Dayton T
2003-03-01
Biomarkers of nutritional status provide alternative measures of dietary intake. Like the error and variation associated with dietary intake measures, the magnitude and impact of both biological (preanalytical) and laboratory (analytical) variability need to be considered when one is using biomarkers. When choosing a biomarker, it is important to understand how it relates to nutritional intake and the specific time frame of exposure it reflects as well as how it is affected by sampling and laboratory procedures. Biological sources of variation that arise from genetic and disease states of an individual affect biomarkers, but they are also affected by nonbiological sources of variation arising from specimen collection and storage, seasonality, time of day, contamination, stability and laboratory quality assurance. When choosing a laboratory for biomarker assessment, researchers should try to make sure random and systematic error is minimized by inclusion of certain techniques such as blinding of laboratory staff to disease status and including external pooled standards to which laboratory staff are blinded. In addition analytic quality control should be ensured by use of internal standards or certified materials over the entire range of possible values to control method accuracy. One must consider the effect of random laboratory error on measurement precision and also understand the method's limit of detection and the laboratory cutpoints. Choosing appropriate cutpoints and reducing error is extremely important in nutritional epidemiology where weak associations are frequent. As part of this review, serum lipids are included as an example of a biomarker whereby collaborative efforts have been put forth to both understand biological sources of variation and standardize laboratory results.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-15
....gov/acs/www/ or contact the Census Bureau's Social, Economic, and Housing Statistics Division at (301...) Sampling Error, which consists of the error that arises from the use of probability sampling to create the... direction; and (2) Sampling Error, which consists of the error that arises from the use of probability...
NASA Astrophysics Data System (ADS)
Acebron, Ana; Jullo, Eric; Limousin, Marceau; Tilquin, André; Giocoli, Carlo; Jauzac, Mathilde; Mahler, Guillaume; Richard, Johan
2017-09-01
Strong gravitational lensing by galaxy clusters is a fundamental tool to study dark matter and constrain the geometry of the Universe. Recently, the Hubble Space Telescope Frontier Fields programme has allowed a significant improvement of mass and magnification measurements but lensing models still have a residual root mean square between 0.2 arcsec and few arcseconds, not yet completely understood. Systematic errors have to be better understood and treated in order to use strong lensing clusters as reliable cosmological probes. We have analysed two simulated Hubble-Frontier-Fields-like clusters from the Hubble Frontier Fields Comparison Challenge, Ares and Hera. We use several estimators (relative bias on magnification, density profiles, ellipticity and orientation) to quantify the goodness of our reconstructions by comparing our multiple models, optimized with the parametric software lenstool, with the input models. We have quantified the impact of systematic errors arising, first, from the choice of different density profiles and configurations and, secondly, from the availability of constraints (spectroscopic or photometric redshifts, redshift ranges of the background sources) in the parametric modelling of strong lensing galaxy clusters and therefore on the retrieval of cosmological parameters. We find that substructures in the outskirts have a significant impact on the position of the multiple images, yielding tighter cosmological contours. The need for wide-field imaging around massive clusters is thus reinforced. We show that competitive cosmological constraints can be obtained also with complex multimodal clusters and that photometric redshifts improve the constraints on cosmological parameters when considering a narrow range of (spectroscopic) redshifts for the sources.
On the X-ray spectrum of the volume emissivity arising from Abell clusters
NASA Technical Reports Server (NTRS)
Stottlemyer, A. R.; Boldt, E. A.
1984-01-01
HEAO 1 A-2 X-ray spectra (2-15 keV) for an optically selected sample of Abell clusters of galaxies with z less than 0.1 have been analyzed to determine the energy dependence of the cosmological X-ray volume emissivity arising from such clusters. This spectrum is well fitted by an isothermal-bremsstrahlung model with kT = 7.4 + or - 1.5 KeV. This result is a test of the isothermal-volume-emissivity spectrum to be inferred from the conjecture that all contributing clusters may be characterized by kT = 7 keV, as assumed by McKee et al. (1980) in estimating the underlying luminosity function for the same sample. Although satisfied at the statistical level indicated, the analysis of a low-luminosity subsample suggests that this assumption of identical isothermal spectra would lead to a systematic error for a more statistically precise determination of the luminosity function's form.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Yashchuk, Valeriy V.; Irick, Steve C.; MacDowell, Alastair A.
2005-04-28
A data acquisition technique and relevant program for suppression of one of the systematic effects, namely the ''ghost'' effect, of a second generation long trace profiler (LTP) is described. The ''ghost'' effect arises when there is an unavoidable cross-contamination of the LTP sample and reference signals into one another, leading to a systematic perturbation in the recorded interference patterns and, therefore, a systematic variation of the measured slope trace. Perturbations of about 1-2 {micro}rad have been observed with a cylindrically shaped X-ray mirror. Even stronger ''ghost'' effects show up in an LTP measurement with a mirror having a toroidal surfacemore » figure. The developed technique employs separate measurement of the ''ghost''-effect-related interference patterns in the sample and the reference arms and then subtraction of the ''ghost'' patterns from the sample and the reference interference patterns. The procedure preserves the advantage of simultaneously measuring the sample and reference signals. The effectiveness of the technique is illustrated with LTP metrology of a variety of X-ray mirrors.« less
Global Warming Estimation from MSU: Correction for Drift and Calibration Errors
NASA Technical Reports Server (NTRS)
Prabhakara, C.; Iacovazzi, R., Jr.; Yoo, J.-M.
2000-01-01
Microwave Sounding Unit (MSU) radiometer observations in Ch 2 (53.74 GHz), made in the nadir direction from sequential, sun-synchronous, polar-orbiting NOAA morning satellites (NOAA 6, 10 and 12 that have approximately 7am/7pm orbital geometry) and. afternoon satellites (NOAA 7, 9, 11 and 14 that have approximately 2am/2pm orbital geometry) are analyzed in this study to derive global temperature trend from 1980 to 1998. In order to remove the discontinuities between the data of the successive satellites and to get a continuous time series, first we have used shortest possible time record of each satellite. In this way we get a preliminary estimate of the global temperature trend of 0.21 K/decade. However, this estimate is affected by systematic time-dependent errors. One such error is the instrument calibration error eo. This error can be inferred whenever there are overlapping measurements made by two satellites over an extended period of time. From the available successive satellite data we have taken the longest possible time record of each satellite to form the time series during the period 1980 to 1998 to this error eo. We find eo can decrease the global temperature trend by approximately 0.07 K/decade. In addition there are systematic time dependent errors ed and ec present in the data that are introduced by the drift in the satellite orbital geometry. ed arises from the diurnal cycle in temperature and ec is the drift related change in the calibration of the MSU. In order to analyze the nature of these drift related errors the multi-satellite Ch 2 data set is partitioned into am and pm subsets to create two independent time series. The error ed can be assessed in the am and pm data of Ch 2 on land and can be eliminated. Observation made in the MSU Ch 1 (50.3 GHz) support this approach. The error ec is obvious only in the difference between the pm and am observations of Ch 2 over the ocean. We have followed two different paths to assess the impact of the error ec on the global temperature trend. In one path the entire error ec is placed in the am data while in the other it is placed in the pm data. Global temperature trend is increased or decreased by approximately 0.03 K/decade depending upon this placement. Taking into account all random errors and systematic errors our analysis of MSU observations leads us to conclude that a conservative estimate of the global warming is 0. 11 (+/-) 0.04 K/decade during 1980 to 1998.
Superresolving Black Hole Images with Full-Closure Sparse Modeling
NASA Astrophysics Data System (ADS)
Crowley, Chelsea; Akiyama, Kazunori; Fish, Vincent
2018-01-01
It is believed that almost all galaxies have black holes at their centers. Imaging a black hole is a primary objective to answer scientific questions relating to relativistic accretion and jet formation. The Event Horizon Telescope (EHT) is set to capture images of two nearby black holes, Sagittarius A* at the center of the Milky Way galaxy roughly 26,000 light years away and the other M87 which is in Virgo A, a large elliptical galaxy that is 50 million light years away. Sparse imaging techniques have shown great promise for reconstructing high-fidelity superresolved images of black holes from simulated data. Previous work has included the effects of atmospheric phase errors and thermal noise, but not systematic amplitude errors that arise due to miscalibration. We explore a full-closure imaging technique with sparse modeling that uses closure amplitudes and closure phases to improve the imaging process. This new technique can successfully handle data with systematic amplitude errors. Applying our technique to synthetic EHT data of M87, we find that full-closure sparse modeling can reconstruct images better than traditional methods and recover key structural information on the source, such as the shape and size of the predicted photon ring. These results suggest that our new approach will provide superior imaging performance for data from the EHT and other interferometric arrays.
PHYSICAL PROPERTIES OF THE 0.94-DAY PERIOD TRANSITING PLANETARY SYSTEM WASP-18
DOE Office of Scientific and Technical Information (OSTI.GOV)
Southworth, John; Anderson, D. R.; Maxted, P. F. L.
2009-12-10
We present high-precision photometry of five consecutive transits of WASP-18, an extrasolar planetary system with one of the shortest orbital periods known. Through the use of telescope defocusing we achieve a photometric precision of 0.47-0.83 mmag per observation over complete transit events. The data are analyzed using the JKTEBOP code and three different sets of stellar evolutionary models. We find the mass and radius of the planet to be M {sub b} = 10.43 +- 0.30 +- 0.24 M {sub Jup} and R {sub b} = 1.165 +- 0.055 +- 0.014 R {sub Jup} (statistical and systematic errors), respectively. Themore » systematic errors in the orbital separation and the stellar and planetary masses, arising from the use of theoretical predictions, are of a similar size to the statistical errors and set a limit on our understanding of the WASP-18 system. We point out that seven of the nine known massive transiting planets (M {sub b} > 3 M {sub Jup}) have eccentric orbits, whereas significant orbital eccentricity has been detected for only four of the 46 less-massive planets. This may indicate that there are two different populations of transiting planets, but could also be explained by observational biases. Further radial velocity observations of low-mass planets will make it possible to choose between these two scenarios.« less
Sari, A Akbari; Doshmangir, L; Sheldon, T
2010-01-01
Understanding the nature and causes of medical adverse events may help their prevention. This systematic review explores the types, risk factors, and likely causes of preventable adverse events in the hospital sector. MEDLINE (1970-2008), EMBASE, CINAHL (1970-2005) and the reference lists were used to identify the studies and a structured narrative method used to synthesise the data. Operative adverse events were more common but less preventable and diagnostic adverse events less common but more preventable than other adverse events. Preventable adverse events were often associated with more than one contributory factor. The majority of adverse events were linked to individual human error, and a significant proportion of these caused serious patient harm. Equipment failure was involved in a small proportion of adverse events and rarely caused patient harm. The proportion of system failures varied widely ranging from 3% to 85% depending on the data collection and classification methods used. Operative adverse events are more common but less preventable than diagnostic adverse events. Adverse events are usually associated with more than one contributory factor, the majority are linked to individual human error, and a proportion of these with system failure.
Identification and correction of systematic error in high-throughput sequence data
2011-01-01
Background A feature common to all DNA sequencing technologies is the presence of base-call errors in the sequenced reads. The implications of such errors are application specific, ranging from minor informatics nuisances to major problems affecting biological inferences. Recently developed "next-gen" sequencing technologies have greatly reduced the cost of sequencing, but have been shown to be more error prone than previous technologies. Both position specific (depending on the location in the read) and sequence specific (depending on the sequence in the read) errors have been identified in Illumina and Life Technology sequencing platforms. We describe a new type of systematic error that manifests as statistically unlikely accumulations of errors at specific genome (or transcriptome) locations. Results We characterize and describe systematic errors using overlapping paired reads from high-coverage data. We show that such errors occur in approximately 1 in 1000 base pairs, and that they are highly replicable across experiments. We identify motifs that are frequent at systematic error sites, and describe a classifier that distinguishes heterozygous sites from systematic error. Our classifier is designed to accommodate data from experiments in which the allele frequencies at heterozygous sites are not necessarily 0.5 (such as in the case of RNA-Seq), and can be used with single-end datasets. Conclusions Systematic errors can easily be mistaken for heterozygous sites in individuals, or for SNPs in population analyses. Systematic errors are particularly problematic in low coverage experiments, or in estimates of allele-specific expression from RNA-Seq data. Our characterization of systematic error has allowed us to develop a program, called SysCall, for identifying and correcting such errors. We conclude that correction of systematic errors is important to consider in the design and interpretation of high-throughput sequencing experiments. PMID:22099972
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-12
... Household Economic Statistics Division at (301) 763-3243. Under the advice of the Census Bureau, HHS..., which consists of the error that arises from the use of probability sampling to create the sample. For...) Sampling Error, which consists of the error that arises from the use of probability sampling to create the...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Adare, A.; Aidala, C.; Ajitanand, N. N.
2015-02-02
We present midrapidity charged-pion invariant cross sections, the ratio of the π⁻ to π⁺ cross sections and the charge-separated double-spin asymmetries in polarized p+p collisions at √s = 200 GeV. While the cross section measurements are consistent within the errors of next-to-leadingorder (NLO) perturbative quantum chromodynamics predictions (pQCD), the same calculations over estimate the ratio of the charged-pion cross sections. This discrepancy arises from the cancellation of the substantial systematic errors associated with the NLO-pQCD predictions in the ratio and highlights the constraints these data will place on flavor dependent pion fragmentation functions. Thus, the charge-separated pion asymmetries presented heremore » sample an x range of ~0.03–0.16 and provide unique information on the sign of the gluon-helicity distribution.« less
NASA Astrophysics Data System (ADS)
Adare, A.; Aidala, C.; Ajitanand, N. N.; Akiba, Y.; Akimoto, R.; Al-Ta'Ani, H.; Alexander, J.; Andrews, K. R.; Angerami, A.; Aoki, K.; Apadula, N.; Appelt, E.; Aramaki, Y.; Armendariz, R.; Aschenauer, E. C.; Atomssa, E. T.; Awes, T. C.; Azmoun, B.; Babintsev, V.; Bai, M.; Bannier, B.; Barish, K. N.; Bassalleck, B.; Basye, A. T.; Bathe, S.; Baublis, V.; Baumann, C.; Bazilevsky, A.; Belmont, R.; Ben-Benjamin, J.; Bennett, R.; Blau, D. S.; Bok, J. S.; Boyle, K.; Brooks, M. L.; Broxmeyer, D.; Buesching, H.; Bumazhnov, V.; Bunce, G.; Butsyk, S.; Campbell, S.; Castera, P.; Chen, C.-H.; Chi, C. Y.; Chiu, M.; Choi, I. J.; Choi, J. B.; Choudhury, R. K.; Christiansen, P.; Chujo, T.; Chvala, O.; Cianciolo, V.; Citron, Z.; Cole, B. A.; Conesa Del Valle, Z.; Connors, M.; Csanád, M.; Csörgő, T.; Dairaku, S.; Datta, A.; David, G.; Dayananda, M. K.; Denisov, A.; Deshpande, A.; Desmond, E. J.; Dharmawardane, K. V.; Dietzsch, O.; Dion, A.; Donadelli, M.; Drapier, O.; Drees, A.; Drees, K. A.; Durham, J. M.; Durum, A.; D'Orazio, L.; Efremenko, Y. V.; Engelmore, T.; Enokizono, A.; En'yo, H.; Esumi, S.; Fadem, B.; Fields, D. E.; Finger, M.; Finger, M.; Fleuret, F.; Fokin, S. L.; Frantz, J. E.; Franz, A.; Frawley, A. D.; Fukao, Y.; Fusayasu, T.; Gal, C.; Garishvili, I.; Giordano, F.; Glenn, A.; Gong, X.; Gonin, M.; Goto, Y.; Granier de Cassagnac, R.; Grau, N.; Greene, S. V.; Grosse Perdekamp, M.; Gunji, T.; Guo, L.; Gustafsson, H.-Å.; Haggerty, J. S.; Hahn, K. I.; Hamagaki, H.; Hamblen, J.; Han, R.; Hanks, J.; Harper, C.; Hashimoto, K.; Haslum, E.; Hayano, R.; He, X.; Hemmick, T. K.; Hester, T.; Hill, J. C.; Hollis, R. S.; Holzmann, W.; Homma, K.; Hong, B.; Horaguchi, T.; Hori, Y.; Hornback, D.; Huang, S.; Ichihara, T.; Ichimiya, R.; Iinuma, H.; Ikeda, Y.; Imai, K.; Inaba, M.; Iordanova, A.; Isenhower, D.; Ishihara, M.; Issah, M.; Ivanischev, D.; Iwanaga, Y.; Jacak, B. V.; Jia, J.; Jiang, X.; John, D.; Johnson, B. M.; Jones, T.; Joo, K. S.; Jouan, D.; Kamin, J.; Kaneti, S.; Kang, B. H.; Kang, J. H.; Kang, J. S.; Kapustinsky, J.; Karatsu, K.; Kasai, M.; Kawall, D.; Kazantsev, A. V.; Kempel, T.; Khanzadeev, A.; Kijima, K. M.; Kim, B. I.; Kim, D. J.; Kim, E.-J.; Kim, Y.-J.; Kim, Y. K.; Kinney, E.; Kiss, Á.; Kistenev, E.; Kleinjan, D.; Kline, P.; Kochenda, L.; Komkov, B.; Konno, M.; Koster, J.; Kotov, D.; Král, A.; Kunde, G. J.; Kurita, K.; Kurosawa, M.; Kwon, Y.; Kyle, G. S.; Lacey, R.; Lai, Y. S.; Lajoie, J. G.; Lebedev, A.; Lee, D. M.; Lee, J.; Lee, K. B.; Lee, K. S.; Lee, S. H.; Lee, S. R.; Leitch, M. J.; Leite, M. A. L.; Li, X.; Lim, S. H.; Linden Levy, L. A.; Liu, H.; Liu, M. X.; Love, B.; Lynch, D.; Maguire, C. F.; Makdisi, Y. I.; Manion, A.; Manko, V. I.; Mannel, E.; Mao, Y.; Masui, H.; McCumber, M.; McGaughey, P. L.; McGlinchey, D.; McKinney, C.; Means, N.; Mendoza, M.; Meredith, B.; Miake, Y.; Mibe, T.; Mignerey, A. C.; Miki, K.; Milov, A.; Mitchell, J. T.; Miyachi, Y.; Mohanty, A. K.; Moon, H. J.; Morino, Y.; Morreale, A.; Morrison, D. P.; Motschwiller, S.; Moukhanova, T. V.; Murakami, T.; Murata, J.; Nagamiya, S.; Nagle, J. L.; Naglis, M.; Nagy, M. I.; Nakagawa, I.; Nakamiya, Y.; Nakamura, K. R.; Nakamura, T.; Nakano, K.; Newby, J.; Nguyen, M.; Nihashi, M.; Nouicer, R.; Nyanin, A. S.; Oakley, C.; O'Brien, E.; Ogilvie, C. A.; Oka, M.; Okada, K.; Oskarsson, A.; Ouchida, M.; Ozawa, K.; Pak, R.; Pantuev, V.; Papavassiliou, V.; Park, B. H.; Park, I. H.; Park, S. K.; Pate, S. F.; Patel, L.; Pei, H.; Peng, J.-C.; Pereira, H.; Peressounko, D. Yu.; Petti, R.; Pinkenburg, C.; Pisani, R. P.; Proissl, M.; Purschke, M. L.; Qu, H.; Rak, J.; Ravinovich, I.; Read, K. F.; Reygers, K.; Riabov, V.; Riabov, Y.; Richardson, E.; Roach, D.; Roche, G.; Rolnick, S. D.; Rosati, M.; Rosendahl, S. S. E.; Rubin, J. G.; Sahlmueller, B.; Saito, N.; Sakaguchi, T.; Samsonov, V.; Sano, S.; Sarsour, M.; Sato, T.; Savastio, M.; Sawada, S.; Sedgwick, K.; Seidl, R.; Seto, R.; Sharma, D.; Shein, I.; Shibata, T.-A.; Shigaki, K.; Shim, H. H.; Shimomura, M.; Shoji, K.; Shukla, P.; Sickles, A.; Silva, C. L.; Silvermyr, D.; Silvestre, C.; Sim, K. S.; Singh, B. K.; Singh, C. P.; Singh, V.; Slunečka, M.; Sodre, T.; Soltz, R. A.; Sondheim, W. E.; Sorensen, S. P.; Sourikova, I. V.; Stankus, P. W.; Stenlund, E.; Stoll, S. P.; Sugitate, T.; Sukhanov, A.; Sun, J.; Sziklai, J.; Takagui, E. M.; Takahara, A.; Taketani, A.; Tanabe, R.; Tanaka, Y.; Taneja, S.; Tanida, K.; Tannenbaum, M. J.; Tarafdar, S.; Taranenko, A.; Tennant, E.; Themann, H.; Thomas, D.; Togawa, M.; Tomášek, L.; Tomášek, M.; Torii, H.; Towell, R. S.; Tserruya, I.; Tsuchimoto, Y.; Utsunomiya, K.; Vale, C.; van Hecke, H. W.; Vazquez-Zambrano, E.; Veicht, A.; Velkovska, J.; Vértesi, R.; Virius, M.; Vossen, A.; Vrba, V.; Vznuzdaev, E.; Wang, X. R.; Watanabe, D.; Watanabe, K.; Watanabe, Y.; Watanabe, Y. S.; Wei, F.; Wei, R.; Wessels, J.; White, S. N.; Winter, D.; Woody, C. L.; Wright, R. M.; Wysocki, M.; Yamaguchi, Y. L.; Yang, R.; Yanovich, A.; Ying, J.; Yokkaichi, S.; Yoo, J. S.; You, Z.; Young, G. R.; Younus, I.; Yushmanov, I. E.; Zajc, W. A.; Zelenski, A.; Zhou, S.; Phenix Collaboration
2015-02-01
We present midrapidity charged-pion invariant cross sections, the ratio of the π- to π+ cross sections and the charge-separated double-spin asymmetries in polarized p +p collisions at √{s }=200 GeV . While the cross section measurements are consistent within the errors of next-to-leading-order (NLO) perturbative quantum chromodynamics predictions (pQCD), the same calculations overestimate the ratio of the charged-pion cross sections. This discrepancy arises from the cancellation of the substantial systematic errors associated with the NLO-pQCD predictions in the ratio and highlights the constraints these data will place on flavor-dependent pion fragmentation functions. The charge-separated pion asymmetries presented here sample an x range of ˜0.03 - 0.16 and provide unique information on the sign of the gluon-helicity distribution.
Integrated Data Analysis for Fusion: A Bayesian Tutorial for Fusion Diagnosticians
NASA Astrophysics Data System (ADS)
Dinklage, Andreas; Dreier, Heiko; Fischer, Rainer; Gori, Silvio; Preuss, Roland; Toussaint, Udo von
2008-03-01
Integrated Data Analysis (IDA) offers a unified way of combining information relevant to fusion experiments. Thereby, IDA meets with typical issues arising in fusion data analysis. In IDA, all information is consistently formulated as probability density functions quantifying uncertainties in the analysis within the Bayesian probability theory. For a single diagnostic, IDA allows the identification of faulty measurements and improvements in the setup. For a set of diagnostics, IDA gives joint error distributions allowing the comparison and integration of different diagnostics results. Validation of physics models can be performed by model comparison techniques. Typical data analysis applications benefit from IDA capabilities of nonlinear error propagation, the inclusion of systematic effects and the comparison of different physics models. Applications range from outlier detection, background discrimination, model assessment and design of diagnostics. In order to cope with next step fusion device requirements, appropriate techniques are explored for fast analysis applications.
Topping, David J.; Rubin, David M.; Wright, Scott A.; Melis, Theodore S.
2011-01-01
Several common methods for measuring suspended-sediment concentration in rivers in the United States use depth-integrating samplers to collect a velocity-weighted suspended-sediment sample in a subsample of a river cross section. Because depth-integrating samplers are always moving through the water column as they collect a sample, and can collect only a limited volume of water and suspended sediment, they collect only minimally time-averaged data. Four sources of error exist in the field use of these samplers: (1) bed contamination, (2) pressure-driven inrush, (3) inadequate sampling of the cross-stream spatial structure in suspended-sediment concentration, and (4) inadequate time averaging. The first two of these errors arise from misuse of suspended-sediment samplers, and the third has been the subject of previous study using data collected in the sand-bedded Middle Loup River in Nebraska. Of these four sources of error, the least understood source of error arises from the fact that depth-integrating samplers collect only minimally time-averaged data. To evaluate this fourth source of error, we collected suspended-sediment data between 1995 and 2007 at four sites on the Colorado River in Utah and Arizona, using a P-61 suspended-sediment sampler deployed in both point- and one-way depth-integrating modes, and D-96-A1 and D-77 bag-type depth-integrating suspended-sediment samplers. These data indicate that the minimal duration of time averaging during standard field operation of depth-integrating samplers leads to an error that is comparable in magnitude to that arising from inadequate sampling of the cross-stream spatial structure in suspended-sediment concentration. This random error arising from inadequate time averaging is positively correlated with grain size and does not largely depend on flow conditions or, for a given size class of suspended sediment, on elevation above the bed. Averaging over time scales >1 minute is the likely minimum duration required to result in substantial decreases in this error. During standard two-way depth integration, a depth-integrating suspended-sediment sampler collects a sample of the water-sediment mixture during two transits at each vertical in a cross section: one transit while moving from the water surface to the bed, and another transit while moving from the bed to the water surface. As the number of transits is doubled at an individual vertical, this error is reduced by ~30 percent in each size class of suspended sediment. For a given size class of suspended sediment, the error arising from inadequate sampling of the cross-stream spatial structure in suspended-sediment concentration depends only on the number of verticals collected, whereas the error arising from inadequate time averaging depends on both the number of verticals collected and the number of transits collected at each vertical. Summing these two errors in quadrature yields a total uncertainty in an equal-discharge-increment (EDI) or equal-width-increment (EWI) measurement of the time-averaged velocity-weighted suspended-sediment concentration in a river cross section (exclusive of any laboratory-processing errors). By virtue of how the number of verticals and transits influences the two individual errors within this total uncertainty, the error arising from inadequate time averaging slightly dominates that arising from inadequate sampling of the cross-stream spatial structure in suspended-sediment concentration. Adding verticals to an EDI or EWI measurement is slightly more effective in reducing the total uncertainty than adding transits only at each vertical, because a new vertical contributes both temporal and spatial information. However, because collection of depth-integrated samples at more transits at each vertical is generally easier and faster than at more verticals, addition of a combination of verticals and transits is likely a more practical approach to reducing the total uncertainty in most field situatio
Uncertainty Propagation in OMFIT
NASA Astrophysics Data System (ADS)
Smith, Sterling; Meneghini, Orso; Sung, Choongki
2017-10-01
A rigorous comparison of power balance fluxes and turbulent model fluxes requires the propagation of uncertainties in the kinetic profiles and their derivatives. Making extensive use of the python uncertainties package, the OMFIT framework has been used to propagate covariant uncertainties to provide an uncertainty in the power balance calculation from the ONETWO code, as well as through the turbulent fluxes calculated by the TGLF code. The covariant uncertainties arise from fitting 1D (constant on flux surface) density and temperature profiles and associated random errors with parameterized functions such as a modified tanh. The power balance and model fluxes can then be compared with quantification of the uncertainties. No effort is made at propagating systematic errors. A case study will be shown for the effects of resonant magnetic perturbations on the kinetic profiles and fluxes at the top of the pedestal. A separate attempt at modeling the random errors with Monte Carlo sampling will be compared to the method of propagating the fitting function parameter covariant uncertainties. Work supported by US DOE under DE-FC02-04ER54698, DE-FG2-95ER-54309, DE-SC 0012656.
Surman, Rebecca; Mumpower, Matthew; McLaughlin, Gail
2017-02-27
Unknown nuclear masses are a major source of nuclear physics uncertainty for r-process nucleosynthesis calculations. Here we examine the systematic and statistical uncertainties that arise in r-process abundance predictions due to uncertainties in the masses of nuclear species on the neutron-rich side of stability. There is a long history of examining systematic uncertainties by the application of a variety of different mass models to r-process calculations. Here we expand upon such efforts by examining six DFT mass models, where we capture the full impact of each mass model by updating the other nuclear properties — including neutron capture rates, β-decaymore » lifetimes, and β-delayed neutron emission probabilities — that depend on the masses. Unlike systematic effects, statistical uncertainties in the r-process pattern have just begun to be explored. Here we apply a global Monte Carlo approach, starting from the latest FRDM masses and considering random mass variations within the FRDM rms error. Here, we find in each approach that uncertain nuclear masses produce dramatic uncertainties in calculated r-process yields, which can be reduced in upcoming experimental campaigns.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Surman, Rebecca; Mumpower, Matthew; McLaughlin, Gail
Unknown nuclear masses are a major source of nuclear physics uncertainty for r-process nucleosynthesis calculations. Here we examine the systematic and statistical uncertainties that arise in r-process abundance predictions due to uncertainties in the masses of nuclear species on the neutron-rich side of stability. There is a long history of examining systematic uncertainties by the application of a variety of different mass models to r-process calculations. Here we expand upon such efforts by examining six DFT mass models, where we capture the full impact of each mass model by updating the other nuclear properties — including neutron capture rates, β-decaymore » lifetimes, and β-delayed neutron emission probabilities — that depend on the masses. Unlike systematic effects, statistical uncertainties in the r-process pattern have just begun to be explored. Here we apply a global Monte Carlo approach, starting from the latest FRDM masses and considering random mass variations within the FRDM rms error. Here, we find in each approach that uncertain nuclear masses produce dramatic uncertainties in calculated r-process yields, which can be reduced in upcoming experimental campaigns.« less
A Systematic Approach to Error Free Telemetry
2017-06-28
A SYSTEMATIC APPROACH TO ERROR FREE TELEMETRY 412TW-TIM-17-03 DISTRIBUTION A: Approved for public release. Distribution is...Systematic Approach to Error-Free Telemetry) was submitted by the Commander, 412th Test Wing, Edwards AFB, California 93524. Prepared by...Technical Information Memorandum 3. DATES COVERED (From - Through) February 2016 4. TITLE AND SUBTITLE A Systematic Approach to Error-Free
Keers, Richard N; Williams, Steven D; Cooke, Jonathan; Ashcroft, Darren M
2013-11-01
Underlying systems factors have been seen to be crucial contributors to the occurrence of medication errors. By understanding the causes of these errors, the most appropriate interventions can be designed and implemented to minimise their occurrence. This study aimed to systematically review and appraise empirical evidence relating to the causes of medication administration errors (MAEs) in hospital settings. Nine electronic databases (MEDLINE, EMBASE, International Pharmaceutical Abstracts, ASSIA, PsycINFO, British Nursing Index, CINAHL, Health Management Information Consortium and Social Science Citations Index) were searched between 1985 and May 2013. Inclusion and exclusion criteria were applied to identify eligible publications through title analysis followed by abstract and then full text examination. English language publications reporting empirical data on causes of MAEs were included. Reference lists of included articles and relevant review papers were hand searched for additional studies. Studies were excluded if they did not report data on specific MAEs, used accounts from individuals not directly involved in the MAE concerned or were presented as conference abstracts with insufficient detail. A total of 54 unique studies were included. Causes of MAEs were categorised according to Reason's model of accident causation. Studies were assessed to determine relevance to the research question and how likely the results were to reflect the potential underlying causes of MAEs based on the method(s) used. Slips and lapses were the most commonly reported unsafe acts, followed by knowledge-based mistakes and deliberate violations. Error-provoking conditions influencing administration errors included inadequate written communication (prescriptions, documentation, transcription), problems with medicines supply and storage (pharmacy dispensing errors and ward stock management), high perceived workload, problems with ward-based equipment (access, functionality), patient factors (availability, acuity), staff health status (fatigue, stress) and interruptions/distractions during drug administration. Few studies sought to determine the causes of intravenous MAEs. A number of latent pathway conditions were less well explored, including local working culture and high-level managerial decisions. Causes were often described superficially; this may be related to the use of quantitative surveys and observation methods in many studies, limited use of established error causation frameworks to analyse data and a predominant focus on issues other than the causes of MAEs among studies. As only English language publications were included, some relevant studies may have been missed. Limited evidence from studies included in this systematic review suggests that MAEs are influenced by multiple systems factors, but if and how these arise and interconnect to lead to errors remains to be fully determined. Further research with a theoretical focus is needed to investigate the MAE causation pathway, with an emphasis on ensuring interventions designed to minimise MAEs target recognised underlying causes of errors to maximise their impact.
NASA Technical Reports Server (NTRS)
Barth, Timothy J.
2014-01-01
This workshop presentation discusses the design and implementation of numerical methods for the quantification of statistical uncertainty, including a-posteriori error bounds, for output quantities computed using CFD methods. Hydrodynamic realizations often contain numerical error arising from finite-dimensional approximation (e.g. numerical methods using grids, basis functions, particles) and statistical uncertainty arising from incomplete information and/or statistical characterization of model parameters and random fields. The first task at hand is to derive formal error bounds for statistics given realizations containing finite-dimensional numerical error [1]. The error in computed output statistics contains contributions from both realization error and the error resulting from the calculation of statistics integrals using a numerical method. A second task is to devise computable a-posteriori error bounds by numerically approximating all terms arising in the error bound estimates. For the same reason that CFD calculations including error bounds but omitting uncertainty modeling are only of limited value, CFD calculations including uncertainty modeling but omitting error bounds are only of limited value. To gain maximum value from CFD calculations, a general software package for uncertainty quantification with quantified error bounds has been developed at NASA. The package provides implementations for a suite of numerical methods used in uncertainty quantification: Dense tensorization basis methods [3] and a subscale recovery variant [1] for non-smooth data, Sparse tensorization methods[2] utilizing node-nested hierarchies, Sampling methods[4] for high-dimensional random variable spaces.
A Systematic Error Correction Method for TOVS Radiances
NASA Technical Reports Server (NTRS)
Joiner, Joanna; Rokke, Laurie; Einaudi, Franco (Technical Monitor)
2000-01-01
Treatment of systematic errors is crucial for the successful use of satellite data in a data assimilation system. Systematic errors in TOVS radiance measurements and radiative transfer calculations can be as large or larger than random instrument errors. The usual assumption in data assimilation is that observational errors are unbiased. If biases are not effectively removed prior to assimilation, the impact of satellite data will be lessened and can even be detrimental. Treatment of systematic errors is important for short-term forecast skill as well as the creation of climate data sets. A systematic error correction algorithm has been developed as part of a 1D radiance assimilation. This scheme corrects for spectroscopic errors, errors in the instrument response function, and other biases in the forward radiance calculation for TOVS. Such algorithms are often referred to as tuning of the radiances. The scheme is able to account for the complex, air-mass dependent biases that are seen in the differences between TOVS radiance observations and forward model calculations. We will show results of systematic error correction applied to the NOAA 15 Advanced TOVS as well as its predecessors. We will also discuss the ramifications of inter-instrument bias with a focus on stratospheric measurements.
Tooze, Janet A; Troiano, Richard P; Carroll, Raymond J; Moshfegh, Alanna J; Freedman, Laurence S
2013-06-01
Systematic investigations into the structure of measurement error of physical activity questionnaires are lacking. We propose a measurement error model for a physical activity questionnaire that uses physical activity level (the ratio of total energy expenditure to basal energy expenditure) to relate questionnaire-based reports of physical activity level to true physical activity levels. The 1999-2006 National Health and Nutrition Examination Survey physical activity questionnaire was administered to 433 participants aged 40-69 years in the Observing Protein and Energy Nutrition (OPEN) Study (Maryland, 1999-2000). Valid estimates of participants' total energy expenditure were also available from doubly labeled water, and basal energy expenditure was estimated from an equation; the ratio of those measures estimated true physical activity level ("truth"). We present a measurement error model that accommodates the mixture of errors that arise from assuming a classical measurement error model for doubly labeled water and a Berkson error model for the equation used to estimate basal energy expenditure. The method was then applied to the OPEN Study. Correlations between the questionnaire-based physical activity level and truth were modest (r = 0.32-0.41); attenuation factors (0.43-0.73) indicate that the use of questionnaire-based physical activity level would lead to attenuated estimates of effect size. Results suggest that sample sizes for estimating relationships between physical activity level and disease should be inflated, and that regression calibration can be used to provide measurement error-adjusted estimates of relationships between physical activity and disease.
More on Systematic Error in a Boyle's Law Experiment
ERIC Educational Resources Information Center
McCall, Richard P.
2012-01-01
A recent article in "The Physics Teacher" describes a method for analyzing a systematic error in a Boyle's law laboratory activity. Systematic errors are important to consider in physics labs because they tend to bias the results of measurements. There are numerous laboratory examples and resources that discuss this common source of error.
Registratiom of TM data to digital elevation models
NASA Technical Reports Server (NTRS)
1984-01-01
Several problems arise when attempting to register LANDSAT thematic mapper data to U.S. B Geological Survey digital elevation models (DEMs). The TM data are currently available only in a rotated variant of the Space Oblique Mercator (SOM) map projection. Geometric transforms are thus; required to access TM data in the geodetic coordinates used by the DEMs. Due to positional errors in the TM data, these transforms require some sort of external control. The spatial resolution of TM data exceeds that of the most commonly DEM data. Oversampling DEM data to TM resolution introduces systematic noise. Common terrain processing algorithms (e.g., close computation) compound this problem by acting as high-pass filters.
NASA Astrophysics Data System (ADS)
Lozano, A. I.; Oller, J. C.; Krupa, K.; Ferreira da Silva, F.; Limão-Vieira, P.; Blanco, F.; Muñoz, A.; Colmenares, R.; García, G.
2018-06-01
A novel experimental setup has been implemented to provide accurate electron scattering cross sections from molecules at low and intermediate impact energies (1-300 eV) by measuring the attenuation of a magnetically confined linear electron beam from a molecular target. High-resolution electron energy is achieved through confinement in a magnetic gas trap where electrons are cooled by successive collisions with N2. Additionally, we developed and present a method to correct systematic errors arising from energy and angular resolution limitations. The accuracy of the entire measurement procedure is validated by comparing the N2 total scattering cross section in the considered energy range with benchmark values available in the literature.
SIM Interferometer Testbed (SCDU) Status and Recent Results
NASA Technical Reports Server (NTRS)
Nemati, Bijan; An, Xin; Goullioud, Renaud; Shao, Michael; Shen, Tsae-Pyng; Wehmeier, Udo J.; Weilert, Mark A.; Wang, Xu; Werne, Thomas A.; Wu, Janet P.;
2010-01-01
SIM Lite is a space-borne stellar interferometer capable of searching for Earth-size planets in the habitable zones of nearby stars. This search will require measurement of astrometric angles with sub micro-arcsecond accuracy and optical pathlength differences to 1 picometer by the end of the five-year mission. One of the most significant technical risks in achieving this level of accuracy is from systematic errors that arise from spectral differences between candidate stars and nearby reference stars. The Spectral Calibration Development Unit (SCDU), in operation since 2007, has been used to explore this effect and demonstrate performance meeting SIM goals. In this paper we present the status of this testbed and recent results.
Sobel, Michael E; Lindquist, Martin A
2014-07-01
Functional magnetic resonance imaging (fMRI) has facilitated major advances in understanding human brain function. Neuroscientists are interested in using fMRI to study the effects of external stimuli on brain activity and causal relationships among brain regions, but have not stated what is meant by causation or defined the effects they purport to estimate. Building on Rubin's causal model, we construct a framework for causal inference using blood oxygenation level dependent (BOLD) fMRI time series data. In the usual statistical literature on causal inference, potential outcomes, assumed to be measured without systematic error, are used to define unit and average causal effects. However, in general the potential BOLD responses are measured with stimulus dependent systematic error. Thus we define unit and average causal effects that are free of systematic error. In contrast to the usual case of a randomized experiment where adjustment for intermediate outcomes leads to biased estimates of treatment effects (Rosenbaum, 1984), here the failure to adjust for task dependent systematic error leads to biased estimates. We therefore adjust for systematic error using measured "noise covariates" , using a linear mixed model to estimate the effects and the systematic error. Our results are important for neuroscientists, who typically do not adjust for systematic error. They should also prove useful to researchers in other areas where responses are measured with error and in fields where large amounts of data are collected on relatively few subjects. To illustrate our approach, we re-analyze data from a social evaluative threat task, comparing the findings with results that ignore systematic error.
Technical Note: Introduction of variance component analysis to setup error analysis in radiotherapy
DOE Office of Scientific and Technical Information (OSTI.GOV)
Matsuo, Yukinori, E-mail: ymatsuo@kuhp.kyoto-u.ac.
Purpose: The purpose of this technical note is to introduce variance component analysis to the estimation of systematic and random components in setup error of radiotherapy. Methods: Balanced data according to the one-factor random effect model were assumed. Results: Analysis-of-variance (ANOVA)-based computation was applied to estimate the values and their confidence intervals (CIs) for systematic and random errors and the population mean of setup errors. The conventional method overestimates systematic error, especially in hypofractionated settings. The CI for systematic error becomes much wider than that for random error. The ANOVA-based estimation can be extended to a multifactor model considering multiplemore » causes of setup errors (e.g., interpatient, interfraction, and intrafraction). Conclusions: Variance component analysis may lead to novel applications to setup error analysis in radiotherapy.« less
Propagation of stage measurement uncertainties to streamflow time series
NASA Astrophysics Data System (ADS)
Horner, Ivan; Le Coz, Jérôme; Renard, Benjamin; Branger, Flora; McMillan, Hilary
2016-04-01
Streamflow uncertainties due to stage measurements errors are generally overlooked in the promising probabilistic approaches that have emerged in the last decade. We introduce an original error model for propagating stage uncertainties through a stage-discharge rating curve within a Bayesian probabilistic framework. The method takes into account both rating curve (parametric errors and structural errors) and stage uncertainty (systematic and non-systematic errors). Practical ways to estimate the different types of stage errors are also presented: (1) non-systematic errors due to instrument resolution and precision and non-stationary waves and (2) systematic errors due to gauge calibration against the staff gauge. The method is illustrated at a site where the rating-curve-derived streamflow can be compared with an accurate streamflow reference. The agreement between the two time series is overall satisfying. Moreover, the quantification of uncertainty is also satisfying since the streamflow reference is compatible with the streamflow uncertainty intervals derived from the rating curve and the stage uncertainties. Illustrations from other sites are also presented. Results are much contrasted depending on the site features. In some cases, streamflow uncertainty is mainly due to stage measurement errors. The results also show the importance of discriminating systematic and non-systematic stage errors, especially for long term flow averages. Perspectives for improving and validating the streamflow uncertainty estimates are eventually discussed.
Black hole masses in active galactic nuclei
NASA Astrophysics Data System (ADS)
Denney, Kelly D.
2010-11-01
We present the complete results from two, high sampling-rate, multi-month, spectrophotometric reverberation mapping campaigns undertaken to obtain either new or improved Hbeta reverberation lag measurements for several relatively low-luminosity active galactic nuclei (AGNs). We have reliably measured the time delay between variations in the continuum and Hbeta emission line in seven local Seyfert 1 galaxies. These measurements are used to calculate the mass of the supermassive black hole at the center of each of these AGNs. We place our results in context to the most current calibration of the broad-line region (BLR) RBLR-L relationship, where our results remove many outliers and significantly reduce the scatter at the low-luminosity end of this relationship. A detailed analysis of the data from our high sampling rate, multi-month reverberation mapping campaign in 2007 reveals that the Hbeta emission region within the BLRs of several nearby AGNs exhibit a variety of kinematic behaviors. Through a velocity-resolved reverberation analysis of the broad Hbeta emission-line flux variations in our sample, we reconstruct velocity-resolved kinematic signals for our entire sample and clearly see evidence for outflowing, infalling, and virialized BLR gas motions in NGC 3227, NGC 3516, and NGC 5548, respectively. Finally, we explore the nature of systematic errors that can arise in measurements of black hole masses from single-epoch spectra of AGNs by utilizing the many epochs available for NGC 5548 and PG1229+204 from reverberation mapping databases. In particular, we examine systematics due to AGN variability, contamination due to constant spectral components (i.e., narrow lines and host galaxy flux), data quality (i.e., signal-to-noise ratio, S/N), and blending of spectral features. We investigate the effect that each of these systematics has on the precision and accuracy of single-epoch masses calculated from two commonly-used line-width measures by comparing these results to recent reverberation mapping studies. We then present an error budget which summarizes the minimum observable uncertainties as well as the amount of additional scatter and/or systematic offset that can be expected from the individual sources of error investigated.
Effect of patient setup errors on simultaneously integrated boost head and neck IMRT treatment plans
DOE Office of Scientific and Technical Information (OSTI.GOV)
Siebers, Jeffrey V.; Keall, Paul J.; Wu Qiuwen
2005-10-01
Purpose: The purpose of this study is to determine dose delivery errors that could result from random and systematic setup errors for head-and-neck patients treated using the simultaneous integrated boost (SIB)-intensity-modulated radiation therapy (IMRT) technique. Methods and Materials: Twenty-four patients who participated in an intramural Phase I/II parotid-sparing IMRT dose-escalation protocol using the SIB treatment technique had their dose distributions reevaluated to assess the impact of random and systematic setup errors. The dosimetric effect of random setup error was simulated by convolving the two-dimensional fluence distribution of each beam with the random setup error probability density distribution. Random setup errorsmore » of {sigma} = 1, 3, and 5 mm were simulated. Systematic setup errors were simulated by randomly shifting the patient isocenter along each of the three Cartesian axes, with each shift selected from a normal distribution. Systematic setup error distributions with {sigma} = 1.5 and 3.0 mm along each axis were simulated. Combined systematic and random setup errors were simulated for {sigma} = {sigma} = 1.5 and 3.0 mm along each axis. For each dose calculation, the gross tumor volume (GTV) received by 98% of the volume (D{sub 98}), clinical target volume (CTV) D{sub 90}, nodes D{sub 90}, cord D{sub 2}, and parotid D{sub 50} and parotid mean dose were evaluated with respect to the plan used for treatment for the structure dose and for an effective planning target volume (PTV) with a 3-mm margin. Results: Simultaneous integrated boost-IMRT head-and-neck treatment plans were found to be less sensitive to random setup errors than to systematic setup errors. For random-only errors, errors exceeded 3% only when the random setup error {sigma} exceeded 3 mm. Simulated systematic setup errors with {sigma} = 1.5 mm resulted in approximately 10% of plan having more than a 3% dose error, whereas a {sigma} = 3.0 mm resulted in half of the plans having more than a 3% dose error and 28% with a 5% dose error. Combined random and systematic dose errors with {sigma} = {sigma} = 3.0 mm resulted in more than 50% of plans having at least a 3% dose error and 38% of the plans having at least a 5% dose error. Evaluation with respect to a 3-mm expanded PTV reduced the observed dose deviations greater than 5% for the {sigma} = {sigma} = 3.0 mm simulations to 5.4% of the plans simulated. Conclusions: Head-and-neck SIB-IMRT dosimetric accuracy would benefit from methods to reduce patient systematic setup errors. When GTV, CTV, or nodal volumes are used for dose evaluation, plans simulated including the effects of random and systematic errors deviate substantially from the nominal plan. The use of PTVs for dose evaluation in the nominal plan improves agreement with evaluated GTV, CTV, and nodal dose values under simulated setup errors. PTV concepts should be used for SIB-IMRT head-and-neck squamous cell carcinoma patients, although the size of the margins may be less than those used with three-dimensional conformal radiation therapy.« less
NASA Technical Reports Server (NTRS)
Massa, D.
1980-01-01
This paper discusses systematic errors which arise from exclusive use of the MK system to determine reddening. It is found that implementation of uvby, beta photometry to refine the qualitative MK grid substantially reduces stellar mismatch error. A working definition of 'identical' ubvy, beta types is investigated and the relationship of uvby to B-V color excesses is determined. A comparison is also made of the hydrogen based uvby, beta types with the MK system based on He and metal lines. A small core correlated effective temperature luminosity error in the MK system for the early B stars is observed along with a breakdown of the MK luminosity criteria for the late B stars. The second part investigates the wavelength dependence of interstellar extinction in the ultraviolet wavelength range observed with the TD-1 satellite. In this study the sets of identical stars employed to find reddening are determined more precisely than in previous studies and consist only of normal, nonsupergiant stars. A multivariate analysis of variance techniques in an unbiased coordinate system is used for determining the wavelength dependence of reddening.
Improved estimation of anomalous diffusion exponents in single-particle tracking experiments
NASA Astrophysics Data System (ADS)
Kepten, Eldad; Bronshtein, Irena; Garini, Yuval
2013-05-01
The mean square displacement is a central tool in the analysis of single-particle tracking experiments, shedding light on various biophysical phenomena. Frequently, parameters are extracted by performing time averages on single-particle trajectories followed by ensemble averaging. This procedure, however, suffers from two systematic errors when applied to particles that perform anomalous diffusion. The first is significant at short-time lags and is induced by measurement errors. The second arises from the natural heterogeneity in biophysical systems. We show how to estimate and correct these two errors and improve the estimation of the anomalous parameters for the whole particle distribution. As a consequence, we manage to characterize ensembles of heterogeneous particles even for rather short and noisy measurements where regular time-averaged mean square displacement analysis fails. We apply this method to both simulations and in vivo measurements of telomere diffusion in 3T3 mouse embryonic fibroblast cells. The motion of telomeres is found to be subdiffusive with an average exponent constant in time. Individual telomere exponents are normally distributed around the average exponent. The proposed methodology has the potential to improve experimental accuracy while maintaining lower experimental costs and complexity.
NASA Astrophysics Data System (ADS)
Brogniez, Helene; English, Stephen; Mahfouf, Jean-Francois; Behrendt, Andreas; Berg, Wesley; Boukabara, Sid; Buehler, Stefan Alexander; Chambon, Philippe; Gambacorta, Antonia; Geer, Alan; Ingram, William; Kursinski, E. Robert; Matricardi, Marco; Odintsova, Tatyana A.; Payne, Vivienne H.; Thorne, Peter W.; Tretyakov, Mikhail Yu.; Wang, Junhong
2016-05-01
Several recent studies have observed systematic differences between measurements in the 183.31 GHz water vapor line by space-borne sounders and calculations using radiative transfer models, with inputs from either radiosondes (radiosonde observations, RAOBs) or short-range forecasts by numerical weather prediction (NWP) models. This paper discusses all the relevant categories of observation-based or model-based data, quantifies their uncertainties and separates biases that could be common to all causes from those attributable to a particular cause. Reference observations from radiosondes, Global Navigation Satellite System (GNSS) receivers, differential absorption lidar (DIAL) and Raman lidar are thus overviewed. Biases arising from their calibration procedures, NWP models and data assimilation, instrument biases and radiative transfer models (both the models themselves and the underlying spectroscopy) are presented and discussed. Although presently no single process in the comparisons seems capable of explaining the observed structure of bias, recommendations are made in order to better understand the causes.
Advanced Water Vapor Lidar Detection System
NASA Technical Reports Server (NTRS)
Elsayed-Ali, Hani
1998-01-01
In the present water vapor lidar system, the detected signal is sent over long cables to a waveform digitizer in a CAMAC crate. This has the disadvantage of transmitting analog signals for a relatively long distance, which is subjected to pickup noise, leading to a decrease in the signal to noise ratio. Generally, errors in the measurement of water vapor with the DIAL method arise from both random and systematic sources. Systematic errors in DIAL measurements are caused by both atmospheric and instrumentation effects. The selection of the on-line alexandrite laser with a narrow linewidth, suitable intensity and high spectral purity, and its operation at the center of the water vapor lines, ensures minimum influence in the DIAL measurement that are caused by the laser spectral distribution and avoid system overloads. Random errors are caused by noise in the detected signal. Variability of the photon statistics in the lidar return signal, noise resulting from detector dark current, and noise in the background signal are the main sources of random error. This type of error can be minimized by maximizing the signal to noise ratio. The increase in the signal to noise ratio can be achieved by several ways. One way is to increase the laser pulse energy, by increasing its amplitude or the pulse repetition rate. Another way, is to use a detector system with higher quantum efficiency and lower noise, on the other hand, the selection of a narrow band optical filter that rejects most of the day background light and retains high optical efficiency is an important issue. Following acquisition of the lidar data, we minimize random errors in the DIAL measurement by averaging the data, but this will result in the reduction of the vertical and horizontal resolutions. Thus, a trade off is necessary to achieve a balance between the spatial resolution and the measurement precision. Therefore, the main goal of this research effort is to increase the signal to noise ratio by a factor of 10 over the current system, using a newly evaluated, very low noise avalanche photo diode detector and constructing a 10 MHz waveform digitizer which will replace the current CAMAC system.
Errors in causal inference: an organizational schema for systematic error and random error.
Suzuki, Etsuji; Tsuda, Toshihide; Mitsuhashi, Toshiharu; Mansournia, Mohammad Ali; Yamamoto, Eiji
2016-11-01
To provide an organizational schema for systematic error and random error in estimating causal measures, aimed at clarifying the concept of errors from the perspective of causal inference. We propose to divide systematic error into structural error and analytic error. With regard to random error, our schema shows its four major sources: nondeterministic counterfactuals, sampling variability, a mechanism that generates exposure events and measurement variability. Structural error is defined from the perspective of counterfactual reasoning and divided into nonexchangeability bias (which comprises confounding bias and selection bias) and measurement bias. Directed acyclic graphs are useful to illustrate this kind of error. Nonexchangeability bias implies a lack of "exchangeability" between the selected exposed and unexposed groups. A lack of exchangeability is not a primary concern of measurement bias, justifying its separation from confounding bias and selection bias. Many forms of analytic errors result from the small-sample properties of the estimator used and vanish asymptotically. Analytic error also results from wrong (misspecified) statistical models and inappropriate statistical methods. Our organizational schema is helpful for understanding the relationship between systematic error and random error from a previously less investigated aspect, enabling us to better understand the relationship between accuracy, validity, and precision. Copyright © 2016 Elsevier Inc. All rights reserved.
Cryosat-2 and Sentinel-3 tropospheric corrections: their evaluation over rivers and lakes
NASA Astrophysics Data System (ADS)
Fernandes, Joana; Lázaro, Clara; Vieira, Telmo; Restano, Marco; Ambrózio, Américo; Benveniste, Jérôme
2017-04-01
In the scope of the Sentinel-3 Hydrologic Altimetry PrototypE (SHAPE) project, errors that presently affect the tropospheric corrections i.e. dry and wet tropospheric corrections (DTC and WTC, respectively) given in satellite altimetry products are evaluated over inland water regions. These errors arise because both corrections, function of altitude, are usually computed with respect to an incorrect altitude reference. Several regions of interest (ROI) where CryoSat-2 (CS-2) is operating in SAR/SAR-In modes were selected for this evaluation. In this study, results for Danube River, Amazon Basin, Vanern and Titicaca lakes, and Caspian Sea, using Level 1B CS-2 data, are shown. DTC and WTC have been compared to those derived from ECMWF Operational model and computed at different altitude references: i) ECMWF orography; ii) ACE2 (Altimeter Corrected Elevations 2) and GWD-LR (Global Width Database for Large Rivers) global digital elevation models; iii) mean lake level, derived from Envisat mission data, or river profile derived in the scope of SHAPE project by AlongTrack (ATK) using Jason-2 data. Whenever GNSS data are available in the ROI, a GNSS-derived WTC was also generated and used for comparison. Overall, results show that the tropospheric corrections present in CS-2 L1B products are provided at the level of ECMWF orography, which can depart from the mean lake level or river profile by hundreds of metres. Therefore, the use of the model orography originates errors in the corrections. To mitigate these errors, both DTC and WTC should be provided at the mean river profile/lake level. For example, for the Caspian Sea with a mean level of -27 m, the tropospheric corrections provided in CS-2 products were computed at mean sea level (zero level), leading therefore to a systematic error in the corrections. In case a mean lake level is not available, it can be easily determined from satellite altimetry. In the absence of a mean river profile, both mentioned DEM, considered better altimetric surfaces when compared to the ECMWF orography, can be used. When using the model orography, systematic errors up to 3-5 cm are found in the DTC for most of the selected regions, which can induce significant errors in e.g. the determination of mean river profiles or lake level time series. For the Danube River, larger DTC errors up to 10 cm, due to terrain characteristics, can appear. For the WTC, with higher spatial variability, model errors of magnitude 1-3 cm are expected over inland waters. In the Danube region, the comparison of GNSS- and ECMWF-derived WTC has shown that the error in the WTC computed at orography level can be up to 3 cm. WTC errors with this magnitude have been found for all ROI. Although globally small, these errors are systematic and must be corrected prior to the generation of CS-2 Level 2 products. Once computed at the mean profile and mean lake level, the results show that tropospheric corrections have accuracy better than 1 cm. This analysis is currently being extended to S3 data and the first results are shown.
Homogeneous studies of transiting extrasolar planets - III. Additional planets and stellar models
NASA Astrophysics Data System (ADS)
Southworth, John
2010-11-01
I derive the physical properties of 30 transiting extrasolar planetary systems using a homogeneous analysis of published data. The light curves are modelled with the JKTEBOP code, with special attention paid to the treatment of limb darkening, orbital eccentricity and error analysis. The light from some systems is contaminated by faint nearby stars, which if ignored will systematically bias the results. I show that it is not realistically possible to account for this using only transit light curves: light-curve solutions must be constrained by measurements of the amount of contaminating light. A contamination of 5 per cent is enough to make the measurement of a planetary radius 2 per cent too low. The physical properties of the 30 transiting systems are obtained by interpolating in tabulated predictions from theoretical stellar models to find the best match to the light-curve parameters and the measured stellar velocity amplitude, temperature and metal abundance. Statistical errors are propagated by a perturbation analysis which constructs complete error budgets for each output parameter. These error budgets are used to compile a list of systems which would benefit from additional photometric or spectroscopic measurements. The systematic errors arising from the inclusion of stellar models are assessed by using five independent sets of theoretical predictions for low-mass stars. This model dependence sets a lower limit on the accuracy of measurements of the physical properties of the systems, ranging from 1 per cent for the stellar mass to 0.6 per cent for the mass of the planet and 0.3 per cent for other quantities. The stellar density and the planetary surface gravity and equilibrium temperature are not affected by this model dependence. An external test on these systematic errors is performed by comparing the two discovery papers of the WASP-11/HAT-P-10 system: these two studies differ in their assessment of the ratio of the radii of the components and the effective temperature of the star. I find that the correlations of planetary surface gravity and mass with orbital period have significance levels of only 3.1σ and 2.3σ, respectively. The significance of the latter has not increased with the addition of new data since Paper II. The division of planets into two classes based on Safronov number is increasingly blurred. Most of the objects studied here would benefit from improved photometric and spectroscopic observations, as well as improvements in our understanding of low-mass stars and their effective temperature scale.
Clustering of quasars in SDSS-IV eBOSS: study of potential systematics and bias determination
DOE Office of Scientific and Technical Information (OSTI.GOV)
Laurent, Pierre; Goff, Jean-Marc Le; Burtin, Etienne
2017-07-01
We study the first year of the eBOSS quasar sample in the redshift range 0.9< z <2.2 which includes 68,772 homogeneously selected quasars. We show that the main source of systematics in the evaluation of the correlation function arises from inhomogeneities in the quasar target selection, particularly related to the extinction and depth of the imaging data used for targeting. We propose a weighting scheme that mitigates these systematics. We measure the quasar correlation function and provide the most accurate measurement to date of the quasar bias in this redshift range, b {sub Q} = 2.45 ± 0.05 at z-barmore » =1.55, together with its evolution with redshift. We use this information to determine the minimum mass of the halo hosting the quasars and the characteristic halo mass, which we find to be both independent of redshift within statistical error. Using a recently-measured quasar-luminosity-function we also determine the quasar duty cycle. The size of this first year sample is insufficient to detect any luminosity dependence to quasar clustering and this issue should be further studied with the final ∼500,000 eBOSS quasar sample.« less
Clustering of quasars in SDSS-IV eBOSS: study of potential systematics and bias determination
NASA Astrophysics Data System (ADS)
Laurent, Pierre; Eftekharzadeh, Sarah; Le Goff, Jean-Marc; Myers, Adam; Burtin, Etienne; White, Martin; Ross, Ashley J.; Tinker, Jeremy; Tojeiro, Rita; Bautista, Julian; Brinkmann, Jonathan; Comparat, Johan; Dawson, Kyle; du Mas des Bourboux, Hélion; Kneib, Jean-Paul; McGreer, Ian D.; Palanque-Delabrouille, Nathalie; Percival, Will J.; Prada, Francisco; Rossi, Graziano; Schneider, Donald P.; Weinberg, David; Yèche, Christophe; Zarrouk, Pauline; Zhao, Gong-Bo
2017-07-01
We study the first year of the eBOSS quasar sample in the redshift range 0.9
Self-Calibration of BICEP1 Three-Year Data and Constraints on Astrophysical Polarization Rotation
NASA Technical Reports Server (NTRS)
Kaufman, J. P.; Miller, N. J.; Shimon, M.; Barkats, D.; Bischoff, C.; Buder, I.; Keating, B. G.; Kovac, J. M.; Ade, P. A. R.; Aikin, R.;
2014-01-01
Cosmic microwave background (CMB) polarimeters aspire to measure the faint B-mode signature predicted to arise from inflationary gravitational waves. They also have the potential to constrain cosmic birefringence, rotation of the polarization of the CMB arising from parity-violating physics, which would produce nonzero expectation values for the CMB's temperature to B-mode correlation (TB) and E-mode to B-mode correlation (EB) spectra. However, instrumental systematic effects can also cause these TB and EB correlations to be nonzero. In particular, an overall miscalibration of the polarization orientation of the detectors produces TB and EB spectra which are degenerate with isotropic cosmological birefringence, while also introducing a small but predictable bias on the BB spectrum. We find that BICEP1 three-year spectra, which use our standard calibration of detector polarization angles from a dielectric sheet, are consistent with a polarization rotation of alpha = -2.77deg +/- 0.86deg (statistical) +/- 1.3deg (systematic). We have revised the estimate of systematic error on the polarization rotation angle from the two-year analysis by comparing multiple calibration methods. We also account for the (negligible) impact of measured beam systematic effects. We investigate the polarization rotation for the BICEP1 100 GHz and 150 GHz bands separately to investigate theoretical models that produce frequency-dependent cosmic birefringence. We find no evidence in the data supporting either of these models or Faraday rotation of the CMB polarization by the Milky Way galaxy's magnetic field. If we assume that there is no cosmic birefringence, we can use the TB and EB spectra to calibrate detector polarization orientations, thus reducing bias of the cosmological B-mode spectrum from leaked E-modes due to possible polarization orientation miscalibration. After applying this "self-calibration" process, we find that the upper limit on the tensor-to-scalar ratio decreases slightly, from r < 0.70 to r < 0.65 at 95% confidence.
Seeing in the dark - I. Multi-epoch alchemy
NASA Astrophysics Data System (ADS)
Huff, Eric M.; Hirata, Christopher M.; Mandelbaum, Rachel; Schlegel, David; Seljak, Uroš; Lupton, Robert H.
2014-05-01
Weak lensing by large-scale structure is an invaluable cosmological tool given that most of the energy density of the concordance cosmology is invisible. Several large ground-based imaging surveys will attempt to measure this effect over the coming decade, but reliable control of the spurious lensing signal introduced by atmospheric turbulence and telescope optics remains a challenging problem. We address this challenge with a demonstration that point spread function (PSF) effects on measured galaxy shapes in the Sloan Digital Sky Survey (SDSS) can be corrected with existing analysis techniques. In this work, we co-add existing SDSS imaging on the equatorial stripe in order to build a data set with the statistical power to measure cosmic shear, while using a rounding kernel method to null out the effects of the anisotropic PSF. We build a galaxy catalogue from the combined imaging, characterize its photometric properties and show that the spurious shear remaining in this catalogue after the PSF correction is negligible compared to the expected cosmic shear signal. We identify a new source of systematic error in the shear-shear autocorrelations arising from selection biases related to masking. Finally, we discuss the circumstances in which this method is expected to be useful for upcoming ground-based surveys that have lensing as one of the science goals, and identify the systematic errors that can reduce its efficacy.
NASA Astrophysics Data System (ADS)
Alexandrou, C.; Constantinou, M.; Dimopoulos, P.; Frezzotti, R.; Hadjiyiannakou, K.; Jansen, K.; Kallidonis, C.; Kostrzewa, B.; Koutsou, G.; Mangin-Brinet, M.; Vaquero Avilès-Casco, A.; Wenger, U.
2017-06-01
We present results on the light, strange and charm nucleon scalar and tensor charges from lattice QCD, using simulations with Nf=2 flavors of twisted mass clover-improved fermions with a physical value of the pion mass. Both connected and disconnected contributions are included, enabling us to extract the isoscalar, strange and charm charges for the first time directly at the physical point. Furthermore, the renormalization is computed nonperturbatively for both isovector and isoscalar quantities. We investigate excited state effects by analyzing several sink-source time separations and by employing a set of methods to probe ground state dominance. Our final results for the scalar charges are gSu=5.20 (42 )(15 )(12 ), gSd=4.27 (26 )(15 )(12 ), gSs=0.33 (7 )(1 )(4 ), and gSc=0.062 (13 )(3 )(5 ) and for the tensor charges gTu=0.794 (16 )(2 )(13 ), gTd=-0.210 (10 )(2 )(13 ), gTs=0.00032 (24 )(0 ), and gTc=0.00062 (85 )(0 ) in the MS ¯ scheme at 2 GeV. The first error is statistical, the second is the systematic error due to the renormalization and the third the systematic arising from estimating the contamination due to the excited states, when our data are precise enough to probe the first excited state.
Basis set limit and systematic errors in local-orbital based all-electron DFT
NASA Astrophysics Data System (ADS)
Blum, Volker; Behler, Jörg; Gehrke, Ralf; Reuter, Karsten; Scheffler, Matthias
2006-03-01
With the advent of efficient integration schemes,^1,2 numeric atom-centered orbitals (NAO's) are an attractive basis choice in practical density functional theory (DFT) calculations of nanostructured systems (surfaces, clusters, molecules). Though all-electron, the efficiency of practical implementations promises to be on par with the best plane-wave pseudopotential codes, while having a noticeably higher accuracy if required: Minimal-sized effective tight-binding like calculations and chemically accurate all-electron calculations are both possible within the same framework; non-periodic and periodic systems can be treated on equal footing; and the localized nature of the basis allows in principle for O(N)-like scaling. However, converging an observable with respect to the basis set is less straightforward than with competing systematic basis choices (e.g., plane waves). We here investigate the basis set limit of optimized NAO basis sets in all-electron calculations, using as examples small molecules and clusters (N2, Cu2, Cu4, Cu10). meV-level total energy convergence is possible using <=50 basis functions per atom in all cases. We also find a clear correlation between the errors which arise from underconverged basis sets, and the system geometry (interatomic distance). ^1 B. Delley, J. Chem. Phys. 92, 508 (1990), ^2 J.M. Soler et al., J. Phys.: Condens. Matter 14, 2745 (2002).
Functional integration of vertical flight path and speed control using energy principles
NASA Technical Reports Server (NTRS)
Lambregts, A. A.
1984-01-01
A generalized automatic flight control system was developed which integrates all longitudinal flight path and speed control functions previously provided by a pitch autopilot and autothrottle. In this design, a net thrust command is computed based on total energy demand arising from both flight path and speed targets. The elevator command is computed based on the energy distribution error between flight path and speed. The engine control is configured to produce the commanded net thrust. The design incorporates control strategies and hierarchy to deal systematically and effectively with all aircraft operational requirements, control nonlinearities, and performance limits. Consistent decoupled maneuver control is achieved for all modes and flight conditions without outer loop gain schedules, control law submodes, or control function duplication.
ISAAC Photometric Comparison of ECLIPSE Jitter and the ORAC-DR Equivalent Recipe for ISAAC
NASA Astrophysics Data System (ADS)
Currie, M. J.
2005-12-01
Motivated by a request from astronomers demanding accurate and consistent infrared photometry, I compare the photometry and quality of mosaics generated by the ECLIPSE jitter task and the ORAC-DR JITTER_SELF_FLAT recipe in two fields. The current (v4.9.0) ECLIPSE produces photometry a few percent fainter than ORAC-DR; the systematic trend with magnitude seen in v4.4.1 is now removed. Random errors arising from poor flat-fielding are not resolved. ECLIPSE generates noisier mosaics; ORAC-DR has poorer bias removal in crowded fields and defaults to larger mosaics. ORAC-DR runs a few times slower than ECLIPSE, but its recipe development is measured in weeks, not years.
Systematic Error Study for ALICE charged-jet v2 Measurement
DOE Office of Scientific and Technical Information (OSTI.GOV)
Heinz, M.; Soltz, R.
We study the treatment of systematic errors in the determination of v 2 for charged jets in √ sNN = 2:76 TeV Pb-Pb collisions by the ALICE Collaboration. Working with the reported values and errors for the 0-5% centrality data we evaluate the Χ 2 according to the formulas given for the statistical and systematic errors, where the latter are separated into correlated and shape contributions. We reproduce both the Χ 2 and p-values relative to a null (zero) result. We then re-cast the systematic errors into an equivalent co-variance matrix and obtain identical results, demonstrating that the two methodsmore » are equivalent.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bai, Sen; Li, Guangjun; Wang, Maojie
The purpose of this study was to investigate the effect of multileaf collimator (MLC) leaf position, collimator rotation angle, and accelerator gantry rotation angle errors on intensity-modulated radiotherapy plans for nasopharyngeal carcinoma. To compare dosimetric differences between the simulating plans and the clinical plans with evaluation parameters, 6 patients with nasopharyngeal carcinoma were selected for simulation of systematic and random MLC leaf position errors, collimator rotation angle errors, and accelerator gantry rotation angle errors. There was a high sensitivity to dose distribution for systematic MLC leaf position errors in response to field size. When the systematic MLC position errors weremore » 0.5, 1, and 2 mm, respectively, the maximum values of the mean dose deviation, observed in parotid glands, were 4.63%, 8.69%, and 18.32%, respectively. The dosimetric effect was comparatively small for systematic MLC shift errors. For random MLC errors up to 2 mm and collimator and gantry rotation angle errors up to 0.5°, the dosimetric effect was negligible. We suggest that quality control be regularly conducted for MLC leaves, so as to ensure that systematic MLC leaf position errors are within 0.5 mm. Because the dosimetric effect of 0.5° collimator and gantry rotation angle errors is negligible, it can be concluded that setting a proper threshold for allowed errors of collimator and gantry rotation angle may increase treatment efficacy and reduce treatment time.« less
Errors, Error, and Text in Multidialect Setting.
ERIC Educational Resources Information Center
Candler, W. J.
1979-01-01
This article discusses the various dialects of English spoken in Liberia and analyzes the problems of Liberian students in writing compositions in English. Errors arise mainly from differences in culture and cognition, not from superficial linguistic problems. (CFM)
Gagnon, Bernadine; Miozzo, Michele
2017-01-01
Purpose This study aimed to test whether an approach to distinguishing errors arising in phonological processing from those arising in motor planning also predicts the extent to which repetition-based training can lead to improved production of difficult sound sequences. Method Four individuals with acquired speech production impairment who produced consonant cluster errors involving deletion were examined using a repetition task. We compared the acoustic details of productions with deletion errors in target consonant clusters to singleton consonants. Changes in accuracy over the course of the study were also compared. Results Two individuals produced deletion errors consistent with a phonological locus of the errors, and 2 individuals produced errors consistent with a motoric locus of the errors. The 2 individuals who made phonologically driven errors showed no change in performance on a repetition training task, whereas the 2 individuals with motoric errors improved in their production of both trained and untrained items. Conclusions The results extend previous findings about a metric for identifying the source of sound production errors in individuals with both apraxia of speech and aphasia. In particular, this work may provide a tool for identifying predominant error types in individuals with complex deficits. PMID:28655044
DOE Office of Scientific and Technical Information (OSTI.GOV)
Li, T. S.
Meeting the science goals for many current and future ground-based optical large-area sky surveys requires that the calibrated broadband photometry is stable in time and uniform over the sky to 1% precision or better. Past surveys have achieved photometric precision of 1-2% by calibrating the survey's stellar photometry with repeated measurements of a large number of stars observed in multiple epochs. The calibration techniques employed by these surveys only consider the relative frame-by-frame photometric zeropoint offset and the focal plane position-dependent illumination corrections, which are independent of the source color. However, variations in the wavelength dependence of the atmospheric transmissionmore » and the instrumental throughput induce source color-dependent systematic errors. These systematic errors must also be considered to achieve the most precise photometric measurements. In this paper, we examine such systematic chromatic errors using photometry from the Dark Energy Survey (DES) as an example. We define a natural magnitude system for DES and calculate the systematic errors on stellar magnitudes, when the atmospheric transmission and instrumental throughput deviate from the natural system. We conclude that the systematic chromatic errors caused by the change of airmass in each exposure, the change of the precipitable water vapor and aerosol in the atmosphere over time, and the non-uniformity of instrumental throughput over the focal plane, can be up to 2% in some bandpasses. We compare the calculated systematic chromatic errors with the observed DES data. For the test sample data, we correct these errors using measurements of the atmospheric transmission and instrumental throughput. The residual after correction is less than 0.3%. We also find that the errors for non-stellar objects are redshift-dependent and can be larger than those for stars at certain redshifts.« less
Systematic Errors in an Air Track Experiment.
ERIC Educational Resources Information Center
Ramirez, Santos A.; Ham, Joe S.
1990-01-01
Errors found in a common physics experiment to measure acceleration resulting from gravity using a linear air track are investigated. Glider position at release and initial velocity are shown to be sources of systematic error. (CW)
Mayo-Wilson, Evan; Ng, Sueko Matsumura; Chuck, Roy S; Li, Tianjing
2017-09-05
Systematic reviews should inform American Academy of Ophthalmology (AAO) Preferred Practice Pattern® (PPP) guidelines. The quality of systematic reviews related to the forthcoming Preferred Practice Pattern® guideline (PPP) Refractive Errors & Refractive Surgery is unknown. We sought to identify reliable systematic reviews to assist the AAO Refractive Errors & Refractive Surgery PPP. Systematic reviews were eligible if they evaluated the effectiveness or safety of interventions included in the 2012 PPP Refractive Errors & Refractive Surgery. To identify potentially eligible systematic reviews, we searched the Cochrane Eyes and Vision United States Satellite database of systematic reviews. Two authors identified eligible reviews and abstracted information about the characteristics and quality of the reviews independently using the Systematic Review Data Repository. We classified systematic reviews as "reliable" when they (1) defined criteria for the selection of studies, (2) conducted comprehensive literature searches for eligible studies, (3) assessed the methodological quality (risk of bias) of the included studies, (4) used appropriate methods for meta-analyses (which we assessed only when meta-analyses were reported), (5) presented conclusions that were supported by the evidence provided in the review. We identified 124 systematic reviews related to refractive error; 39 met our eligibility criteria, of which we classified 11 to be reliable. Systematic reviews classified as unreliable did not define the criteria for selecting studies (5; 13%), did not assess methodological rigor (10; 26%), did not conduct comprehensive searches (17; 44%), or used inappropriate quantitative methods (3; 8%). The 11 reliable reviews were published between 2002 and 2016. They included 0 to 23 studies (median = 9) and analyzed 0 to 4696 participants (median = 666). Seven reliable reviews (64%) assessed surgical interventions. Most systematic reviews of interventions for refractive error are low methodological quality. Following widely accepted guidance, such as Cochrane or Institute of Medicine standards for conducting systematic reviews, would contribute to improved patient care and inform future research.
An analysis of the least-squares problem for the DSN systematic pointing error model
NASA Technical Reports Server (NTRS)
Alvarez, L. S.
1991-01-01
A systematic pointing error model is used to calibrate antennas in the Deep Space Network. The least squares problem is described and analyzed along with the solution methods used to determine the model's parameters. Specifically studied are the rank degeneracy problems resulting from beam pointing error measurement sets that incorporate inadequate sky coverage. A least squares parameter subset selection method is described and its applicability to the systematic error modeling process is demonstrated on Voyager 2 measurement distribution.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bouwens, R. J.; Labbé, I.; Franx, M.
2014-10-01
We measure the UV-continuum slope β for over 4000 high-redshift galaxies over a wide range of redshifts z ∼ 4-8 and luminosities from the HST HUDF/XDF, HUDF09-1, HUDF09-2, ERS, CANDELS-N, and CANDELS-S data sets. Our new β results reach very faint levels at z ∼ 4 (–15.5 mag: 0.006 L{sub z=3}{sup ∗}), z ∼ 5 (–16.5 mag: 0.014 L{sub z=3}{sup ∗}), and z ∼ 6 and z ∼ 7 (–17 mag: 0.025 L{sub z=3}{sup ∗}). Inconsistencies between previous studies led us to conduct a comprehensive review of systematic errors and develop a new technique for measuring β that is robustmore » against biases that arise from the impact of noise. We demonstrate, by object-by-object comparisons, that all previous studies, including our own and those done on the latest HUDF12 data set, suffered from small systematic errors in β. We find that after correcting for the systematic errors (typically Δβ ∼ 0.1-0.2) all β results at z ∼ 7 from different groups are in excellent agreement. The mean β we measure for faint (–18 mag: 0.1 L{sub z=3}{sup ∗}) z ∼ 4, z ∼ 5, z ∼ 6, and z ∼ 7 galaxies is –2.03 ± 0.03 ± 0.06 (random and systematic errors), –2.14 ± 0.06 ± 0.06, –2.24 ± 0.11 ± 0.08, and –2.30 ± 0.18 ± 0.13, respectively. Our new β values are redder than we have reported in the past, but bluer than other recent results. Our previously reported trend of bluer β's at lower luminosities is confirmed, as is the evolution to bluer β's at high redshifts. β appears to show only a mild luminosity dependence faintward of M {sub UV,AB} ∼ –19 mag, suggesting that the mean β asymptotes to ∼–2.2 to –2.4 for faint z ≥ 4 galaxies. At z ∼ 7, the observed β's suggest non-zero, but low dust extinction, and they agree well with values predicted in cosmological hydrodynamical simulations.« less
Astrostatistics in X-ray Astronomy: Systematics and Calibration
NASA Astrophysics Data System (ADS)
Siemiginowska, Aneta; Kashyap, Vinay; CHASC
2014-01-01
Astrostatistics has been emerging as a new field in X-ray and gamma-ray astronomy, driven by the analysis challenges arising from data collected by high performance missions since the beginning of this century. The development and implementation of new analysis methods and techniques requires a close collaboration between astronomers and statisticians, and requires support from a reliable and continuous funding source. The NASA AISR program was one such, and played a crucial part in our work. Our group (CHASC; http://heawww.harvard.edu/AstroStat/), composed of a mixture of high energy astrophysicists and statisticians, was formed ~15 years ago to address specific issues related to Chandra X-ray Observatory data (Siemiginowska et al. 1997) and was initially fully supported by Chandra. We have developed several statistical methods that have laid the foundation for extensive application of Bayesian methodologies to Poisson data in high-energy astrophysics. I will describe one such project, on dealing with systematic uncertainties (Lee et al. 2011, ApJ ), and present the implementation of the method in Sherpa, the CIAO modeling and fitting application. This algorithm propagates systematic uncertainties in instrumental responses (e.g., ARFs) through the Sherpa spectral modeling chain to obtain realistic error bars on model parameters when the data quality is high. Recent developments include the ability to narrow the space of allowed calibration and obtain better parameter estimates as well as tighter error bars. Acknowledgements: This research is funded in part by NASA contract NAS8-03060. References: Lee, H., Kashyap, V.L., van Dyk, D.A., et al. 2011, ApJ, 731, 126 Siemiginowska, A., Elvis, M., Connors, A., et al. 1997, Statistical Challenges in Modern Astronomy II, 241
Crocce, M.
2015-12-09
We study the clustering of galaxies detected at i < 22.5 in the Science Verification observations of the Dark Energy Survey (DES). Two-point correlation functions are measured using 2.3 × 106 galaxies over a contiguous 116 deg 2 region in five bins of photometric redshift width Δz = 0.2 in the range 0.2 < z < 1.2. The impact of photometric redshift errors is assessed by comparing results using a template-based photo-zalgorithm (BPZ) to a machine-learning algorithm (TPZ). A companion paper presents maps of several observational variables (e.g. seeing, sky brightness) which could modulate the galaxy density. Here we characterizemore » and mitigate systematic errors on the measured clustering which arise from these observational variables, in addition to others such as Galactic dust and stellar contamination. After correcting for systematic effects, we then measure galaxy bias over a broad range of linear scales relative to mass clustering predicted from the Planck Λ cold dark matter model, finding agreement with the Canada-France-Hawaii Telescope Legacy Survey (CFHTLS) measurements with χ 2 of 4.0 (8.7) with 5 degrees of freedom for the TPZ (BPZ) redshifts. Furthermore, we test a ‘linear bias’ model, in which the galaxy clustering is a fixed multiple of the predicted non-linear dark matter clustering. The precision of the data allows us to determine that the linear bias model describes the observed galaxy clustering to 2.5 percent accuracy down to scales at least 4–10 times smaller than those on which linear theory is expected to be sufficient.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Crocce, M.
We study the clustering of galaxies detected at i < 22.5 in the Science Verification observations of the Dark Energy Survey (DES). Two-point correlation functions are measured using 2.3 × 106 galaxies over a contiguous 116 deg 2 region in five bins of photometric redshift width Δz = 0.2 in the range 0.2 < z < 1.2. The impact of photometric redshift errors is assessed by comparing results using a template-based photo-zalgorithm (BPZ) to a machine-learning algorithm (TPZ). A companion paper presents maps of several observational variables (e.g. seeing, sky brightness) which could modulate the galaxy density. Here we characterizemore » and mitigate systematic errors on the measured clustering which arise from these observational variables, in addition to others such as Galactic dust and stellar contamination. After correcting for systematic effects, we then measure galaxy bias over a broad range of linear scales relative to mass clustering predicted from the Planck Λ cold dark matter model, finding agreement with the Canada-France-Hawaii Telescope Legacy Survey (CFHTLS) measurements with χ 2 of 4.0 (8.7) with 5 degrees of freedom for the TPZ (BPZ) redshifts. Furthermore, we test a ‘linear bias’ model, in which the galaxy clustering is a fixed multiple of the predicted non-linear dark matter clustering. The precision of the data allows us to determine that the linear bias model describes the observed galaxy clustering to 2.5 percent accuracy down to scales at least 4–10 times smaller than those on which linear theory is expected to be sufficient.« less
Estimating alarm thresholds and the number of components in mixture distributions
NASA Astrophysics Data System (ADS)
Burr, Tom; Hamada, Michael S.
2012-09-01
Mixtures of probability distributions arise in many nuclear assay and forensic applications, including nuclear weapon detection, neutron multiplicity counting, and in solution monitoring (SM) for nuclear safeguards. SM data is increasingly used to enhance nuclear safeguards in aqueous reprocessing facilities having plutonium in solution form in many tanks. This paper provides background for mixture probability distributions and then focuses on mixtures arising in SM data. SM data can be analyzed by evaluating transfer-mode residuals defined as tank-to-tank transfer differences, and wait-mode residuals defined as changes during non-transfer modes. A previous paper investigated impacts on transfer-mode and wait-mode residuals of event marking errors which arise when the estimated start and/or stop times of tank events such as transfers are somewhat different from the true start and/or stop times. Event marking errors contribute to non-Gaussian behavior and larger variation than predicted on the basis of individual tank calibration studies. This paper illustrates evidence for mixture probability distributions arising from such event marking errors and from effects such as condensation or evaporation during non-transfer modes, and pump carryover during transfer modes. A quantitative assessment of the sample size required to adequately characterize a mixture probability distribution arising in any context is included.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Okura, Yuki; Futamase, Toshifumi, E-mail: yuki.okura@nao.ac.jp, E-mail: tof@astr.tohoku.ac.jp
This is the third paper on the improvement of systematic errors in weak lensing analysis using an elliptical weight function, referred to as E-HOLICs. In previous papers, we succeeded in avoiding errors that depend on the ellipticity of the background image. In this paper, we investigate the systematic error that depends on the signal-to-noise ratio of the background image. We find that the origin of this error is the random count noise that comes from the Poisson noise of sky counts. The random count noise makes additional moments and centroid shift error, and those first-order effects are canceled in averaging,more » but the second-order effects are not canceled. We derive the formulae that correct this systematic error due to the random count noise in measuring the moments and ellipticity of the background image. The correction formulae obtained are expressed as combinations of complex moments of the image, and thus can correct the systematic errors caused by each object. We test their validity using a simulated image and find that the systematic error becomes less than 1% in the measured ellipticity for objects with an IMCAT significance threshold of {nu} {approx} 11.7.« less
SU-E-T-613: Dosimetric Consequences of Systematic MLC Leaf Positioning Errors
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kathuria, K; Siebers, J
2014-06-01
Purpose: The purpose of this study is to determine the dosimetric consequences of systematic MLC leaf positioning errors for clinical IMRT patient plans so as to establish detection tolerances for quality assurance programs. Materials and Methods: Dosimetric consequences were simulated by extracting mlc delivery instructions from the TPS, altering the file by the specified error, reloading the delivery instructions into the TPS, recomputing dose, and extracting dose-volume metrics for one head-andneck and one prostate patient. Machine error was simulated by offsetting MLC leaves in Pinnacle in a systematic way. Three different algorithms were followed for these systematic offsets, and aremore » as follows: a systematic sequential one-leaf offset (one leaf offset in one segment per beam), a systematic uniform one-leaf offset (same one leaf offset per segment per beam) and a systematic offset of a given number of leaves picked uniformly at random from a given number of segments (5 out of 10 total). Dose to the PTV and normal tissue was simulated. Results: A systematic 5 mm offset of 1 leaf for all delivery segments of all beams resulted in a maximum PTV D98 deviation of 1%. Results showed very low dose error in all reasonably possible machine configurations, rare or otherwise, which could be simulated. Very low error in dose to PTV and OARs was shown in all possible cases of one leaf per beam per segment being offset (<1%), or that of only one leaf per beam being offset (<.2%). The errors resulting from a high number of adjacent leaves (maximum of 5 out of 60 total leaf-pairs) being simultaneously offset in many (5) of the control points (total 10–18 in all beams) per beam, in both the PTV and the OARs analyzed, were similarly low (<2–3%). Conclusions: The above results show that patient shifts and anatomical changes are the main source of errors in dose delivered, not machine delivery. These two sources of error are “visually complementary” and uncorrelated (albeit not additive in the final error) and one can easily incorporate error resulting from machine delivery in an error model based purely on tumor motion.« less
NASA Technical Reports Server (NTRS)
Deloach, Richard; Obara, Clifford J.; Goodman, Wesley L.
2012-01-01
This paper documents a check standard wind tunnel test conducted in the Langley 0.3-Meter Transonic Cryogenic Tunnel (0.3M TCT) that was designed and analyzed using the Modern Design of Experiments (MDOE). The test designed to partition the unexplained variance of typical wind tunnel data samples into two constituent components, one attributable to ordinary random error, and one attributable to systematic error induced by covariate effects. Covariate effects in wind tunnel testing are discussed, with examples. The impact of systematic (non-random) unexplained variance on the statistical independence of sequential measurements is reviewed. The corresponding correlation among experimental errors is discussed, as is the impact of such correlation on experimental results generally. The specific experiment documented herein was organized as a formal test for the presence of unexplained variance in representative samples of wind tunnel data, in order to quantify the frequency with which such systematic error was detected, and its magnitude relative to ordinary random error. Levels of systematic and random error reported here are representative of those quantified in other facilities, as cited in the references.
Measurement time and statistics for a noise thermometer with a synthetic-noise reference
NASA Astrophysics Data System (ADS)
White, D. R.; Benz, S. P.; Labenski, J. R.; Nam, S. W.; Qu, J. F.; Rogalla, H.; Tew, W. L.
2008-08-01
This paper describes methods for reducing the statistical uncertainty in measurements made by noise thermometers using digital cross-correlators and, in particular, for thermometers using pseudo-random noise for the reference signal. First, a discrete-frequency expression for the correlation bandwidth for conventional noise thermometers is derived. It is shown how an alternative frequency-domain computation can be used to eliminate the spectral response of the correlator and increase the correlation bandwidth. The corresponding expressions for the uncertainty in the measurement of pseudo-random noise in the presence of uncorrelated thermal noise are then derived. The measurement uncertainty in this case is less than that for true thermal-noise measurements. For pseudo-random sources generating a frequency comb, an additional small reduction in uncertainty is possible, but at the cost of increasing the thermometer's sensitivity to non-linearity errors. A procedure is described for allocating integration times to further reduce the total uncertainty in temperature measurements. Finally, an important systematic error arising from the calculation of ratios of statistical variables is described.
The Design and Characterization of a Prototype Wideband Voltage Sensor Based on a Resistive Divider
Garnacho, Fernando; Khamlichi, Abderrahim; Rovira, Jorge
2017-01-01
The most important advantage of voltage dividers over traditional voltage transformers is that voltage dividers do not have an iron core with non-linear hysteresis characteristics. The voltage dividers have a linear behavior with respect to over-voltages and a flat frequency response larger frequency range. The weak point of a voltage divider is the influence of external high-voltage (HV) and earth parts in its vicinity. Electrical fields arising from high voltages in neighboring phases and from ground conductors and structures are one of their main sources for systematic measurement errors. This paper describes a shielding voltage divider for a 24 kV medium voltage network insulated in SF6 composed of two resistive-capacitive dividers, one integrated within the other, achieving a flat frequency response up to 10 kHz for ratio error and up to 5 kHz for phase displacement error. The metal shielding improves its immunity against electric and magnetic fields. The characterization performed on the built-in voltage sensor shows an accuracy class of 0.2 for a frequency range from 20 Hz to 5 kHz and a class of 0.5 for 1 Hz up to 20 Hz. A low temperature effect is also achieved for operation conditions of MV power grids. PMID:29149085
The Design and Characterization of a Prototype Wideband Voltage Sensor Based on a Resistive Divider.
Garnacho, Fernando; Khamlichi, Abderrahim; Rovira, Jorge
2017-11-17
The most important advantage of voltage dividers over traditional voltage transformers is that voltage dividers do not have an iron core with non-linear hysteresis characteristics. The voltage dividers have a linear behavior with respect to over-voltages and a flat frequency response larger frequency range. The weak point of a voltage divider is the influence of external high-voltage (HV) and earth parts in its vicinity. Electrical fields arising from high voltages in neighboring phases and from ground conductors and structures are one of their main sources for systematic measurement errors. This paper describes a shielding voltage divider for a 24 kV medium voltage network insulated in SF6 composed of two resistive-capacitive dividers, one integrated within the other, achieving a flat frequency response up to 10 kHz for ratio error and up to 5 kHz for phase displacement error. The metal shielding improves its immunity against electric and magnetic fields. The characterization performed on the built-in voltage sensor shows an accuracy class of 0.2 for a frequency range from 20 Hz to 5 kHz and a class of 0.5 for 1 Hz up to 20 Hz. A low temperature effect is also achieved for operation conditions of MV power grids.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bernardis, F. De; Aiola, S.; Vavagiakis, E. M.
Here, we present a new measurement of the kinematic Sunyaev-Zel'dovich effect using data from the Atacama Cosmology Telescope (ACT) and the Baryon Oscillation Spectroscopic Survey (BOSS). Using 600 square degrees of overlapping sky area, we evaluate the mean pairwise baryon momentum associated with the positions of 50,000 bright galaxies in the BOSS DR11 Large Scale Structure catalog. A non-zero signal arises from the large-scale motions of halos containing the sample galaxies. The data fits an analytical signal model well, with the optical depth to microwave photon scattering as a free parameter determining the overall signal amplitude. We estimate the covariancemore » matrix of the mean pairwise momentum as a function of galaxy separation, using microwave sky simulations, jackknife evaluation, and bootstrap estimates. The most conservative simulation-based errors give signal-to-noise estimates between 3.6 and 4.1 for varying galaxy luminosity cuts. We discuss how the other error determinations can lead to higher signal-to-noise values, and consider the impact of several possible systematic errors. Estimates of the optical depth from the average thermal Sunyaev-Zel'dovich signal at the sample galaxy positions are broadly consistent with those obtained from the mean pairwise momentum signal.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bernardis, F. De; Vavagiakis, E.M.; Niemack, M.D.
We present a new measurement of the kinematic Sunyaev-Zel'dovich effect using data from the Atacama Cosmology Telescope (ACT) and the Baryon Oscillation Spectroscopic Survey (BOSS). Using 600 square degrees of overlapping sky area, we evaluate the mean pairwise baryon momentum associated with the positions of 50,000 bright galaxies in the BOSS DR11 Large Scale Structure catalog. A non-zero signal arises from the large-scale motions of halos containing the sample galaxies. The data fits an analytical signal model well, with the optical depth to microwave photon scattering as a free parameter determining the overall signal amplitude. We estimate the covariance matrixmore » of the mean pairwise momentum as a function of galaxy separation, using microwave sky simulations, jackknife evaluation, and bootstrap estimates. The most conservative simulation-based errors give signal-to-noise estimates between 3.6 and 4.1 for varying galaxy luminosity cuts. We discuss how the other error determinations can lead to higher signal-to-noise values, and consider the impact of several possible systematic errors. Estimates of the optical depth from the average thermal Sunyaev-Zel'dovich signal at the sample galaxy positions are broadly consistent with those obtained from the mean pairwise momentum signal.« less
NASA Technical Reports Server (NTRS)
De Bernardis, F.; Aiola, S.; Vavagiakis, E. M.; Battaglia, N.; Niemack, M. D.; Beall, J.; Becker, D. T.; Bond, J. R.; Calabrese, E.; Cho, H.;
2017-01-01
We present a new measurement of the kinematic Sunyaev-Zel'dovich effect using data from the Atacama Cosmology Telescope (ACT) and the Baryon Oscillation Spectroscopic Survey (BOSS). Using 600 square degrees of overlapping sky area, we evaluate the mean pairwise baryon momentum associated with the positions of 50,000 bright galaxies in the BOSS DR11 Large Scale Structure catalog. A non-zero signal arises from the large-scale motions of halos containing the sample galaxies. The data fits an analytical signal model well, with the optical depth to microwave photon scattering as a free parameter determining the overall signal amplitude. We estimate the covariance matrix of the mean pairwise momentum as a function of galaxy separation, using microwave sky simulations, jackknife evaluation, and bootstrap estimates. The most conservative simulation-based errors give signal-to-noise estimates between 3.6 and 4.1 for varying galaxy luminosity cuts. We discuss how the other error determinations can lead to higher signal-to-noise values, and consider the impact of several possible systematic errors. Estimates of the optical depth from the average thermal Sunyaev-Zel'dovich signal at the sample galaxy positions are broadly consistent with those obtained from the mean pairwise momentum signal.
NASA Astrophysics Data System (ADS)
De Bernardis, F.; Aiola, S.; Vavagiakis, E. M.; Battaglia, N.; Niemack, M. D.; Beall, J.; Becker, D. T.; Bond, J. R.; Calabrese, E.; Cho, H.; Coughlin, K.; Datta, R.; Devlin, M.; Dunkley, J.; Dunner, R.; Ferraro, S.; Fox, A.; Gallardo, P. A.; Halpern, M.; Hand, N.; Hasselfield, M.; Henderson, S. W.; Hill, J. C.; Hilton, G. C.; Hilton, M.; Hincks, A. D.; Hlozek, R.; Hubmayr, J.; Huffenberger, K.; Hughes, J. P.; Irwin, K. D.; Koopman, B. J.; Kosowsky, A.; Li, D.; Louis, T.; Lungu, M.; Madhavacheril, M. S.; Maurin, L.; McMahon, J.; Moodley, K.; Naess, S.; Nati, F.; Newburgh, L.; Nibarger, J. P.; Page, L. A.; Partridge, B.; Schaan, E.; Schmitt, B. L.; Sehgal, N.; Sievers, J.; Simon, S. M.; Spergel, D. N.; Staggs, S. T.; Stevens, J. R.; Thornton, R. J.; van Engelen, A.; Van Lanen, J.; Wollack, E. J.
2017-03-01
We present a new measurement of the kinematic Sunyaev-Zel'dovich effect using data from the Atacama Cosmology Telescope (ACT) and the Baryon Oscillation Spectroscopic Survey (BOSS). Using 600 square degrees of overlapping sky area, we evaluate the mean pairwise baryon momentum associated with the positions of 50,000 bright galaxies in the BOSS DR11 Large Scale Structure catalog. A non-zero signal arises from the large-scale motions of halos containing the sample galaxies. The data fits an analytical signal model well, with the optical depth to microwave photon scattering as a free parameter determining the overall signal amplitude. We estimate the covariance matrix of the mean pairwise momentum as a function of galaxy separation, using microwave sky simulations, jackknife evaluation, and bootstrap estimates. The most conservative simulation-based errors give signal-to-noise estimates between 3.6 and 4.1 for varying galaxy luminosity cuts. We discuss how the other error determinations can lead to higher signal-to-noise values, and consider the impact of several possible systematic errors. Estimates of the optical depth from the average thermal Sunyaev-Zel'dovich signal at the sample galaxy positions are broadly consistent with those obtained from the mean pairwise momentum signal.
Bernardis, F. De; Aiola, S.; Vavagiakis, E. M.; ...
2017-03-07
Here, we present a new measurement of the kinematic Sunyaev-Zel'dovich effect using data from the Atacama Cosmology Telescope (ACT) and the Baryon Oscillation Spectroscopic Survey (BOSS). Using 600 square degrees of overlapping sky area, we evaluate the mean pairwise baryon momentum associated with the positions of 50,000 bright galaxies in the BOSS DR11 Large Scale Structure catalog. A non-zero signal arises from the large-scale motions of halos containing the sample galaxies. The data fits an analytical signal model well, with the optical depth to microwave photon scattering as a free parameter determining the overall signal amplitude. We estimate the covariancemore » matrix of the mean pairwise momentum as a function of galaxy separation, using microwave sky simulations, jackknife evaluation, and bootstrap estimates. The most conservative simulation-based errors give signal-to-noise estimates between 3.6 and 4.1 for varying galaxy luminosity cuts. We discuss how the other error determinations can lead to higher signal-to-noise values, and consider the impact of several possible systematic errors. Estimates of the optical depth from the average thermal Sunyaev-Zel'dovich signal at the sample galaxy positions are broadly consistent with those obtained from the mean pairwise momentum signal.« less
Modeling Errors in Daily Precipitation Measurements: Additive or Multiplicative?
NASA Technical Reports Server (NTRS)
Tian, Yudong; Huffman, George J.; Adler, Robert F.; Tang, Ling; Sapiano, Matthew; Maggioni, Viviana; Wu, Huan
2013-01-01
The definition and quantification of uncertainty depend on the error model used. For uncertainties in precipitation measurements, two types of error models have been widely adopted: the additive error model and the multiplicative error model. This leads to incompatible specifications of uncertainties and impedes intercomparison and application.In this letter, we assess the suitability of both models for satellite-based daily precipitation measurements in an effort to clarify the uncertainty representation. Three criteria were employed to evaluate the applicability of either model: (1) better separation of the systematic and random errors; (2) applicability to the large range of variability in daily precipitation; and (3) better predictive skills. It is found that the multiplicative error model is a much better choice under all three criteria. It extracted the systematic errors more cleanly, was more consistent with the large variability of precipitation measurements, and produced superior predictions of the error characteristics. The additive error model had several weaknesses, such as non constant variance resulting from systematic errors leaking into random errors, and the lack of prediction capability. Therefore, the multiplicative error model is a better choice.
Direction Dependent Effects In Widefield Wideband Full Stokes Radio Imaging
NASA Astrophysics Data System (ADS)
Jagannathan, Preshanth; Bhatnagar, Sanjay; Rau, Urvashi; Taylor, Russ
2015-01-01
Synthesis imaging in radio astronomy is affected by instrumental and atmospheric effects which introduce direction dependent gains.The antenna power pattern varies both as a function of time and frequency. The broad band time varying nature of the antenna power pattern when not corrected leads to gross errors in full stokes imaging and flux estimation. In this poster we explore the errors that arise in image deconvolution while not accounting for the time and frequency dependence of the antenna power pattern. Simulations were conducted with the wideband full stokes power pattern of the Very Large Array(VLA) antennas to demonstrate the level of errors arising from direction-dependent gains. Our estimate is that these errors will be significant in wide-band full-pol mosaic imaging as well and algorithms to correct these errors will be crucial for many up-coming large area surveys (e.g. VLASS)
Bias, Confounding, and Interaction: Lions and Tigers, and Bears, Oh My!
Vetter, Thomas R; Mascha, Edward J
2017-09-01
Epidemiologists seek to make a valid inference about the causal effect between an exposure and a disease in a specific population, using representative sample data from a specific population. Clinical researchers likewise seek to make a valid inference about the association between an intervention and outcome(s) in a specific population, based upon their randomly collected, representative sample data. Both do so by using the available data about the sample variable to make a valid estimate about its corresponding or underlying, but unknown population parameter. Random error in an experiment can be due to the natural, periodic fluctuation or variation in the accuracy or precision of virtually any data sampling technique or health measurement tool or scale. In a clinical research study, random error can be due to not only innate human variability but also purely chance. Systematic error in an experiment arises from an innate flaw in the data sampling technique or measurement instrument. In the clinical research setting, systematic error is more commonly referred to as systematic bias. The most commonly encountered types of bias in anesthesia, perioperative, critical care, and pain medicine research include recall bias, observational bias (Hawthorne effect), attrition bias, misclassification or informational bias, and selection bias. A confounding variable is a factor associated with both the exposure of interest and the outcome of interest. A confounding variable (confounding factor or confounder) is a variable that correlates (positively or negatively) with both the exposure and outcome. Confounding is typically not an issue in a randomized trial because the randomized groups are sufficiently balanced on all potential confounding variables, both observed and nonobserved. However, confounding can be a major problem with any observational (nonrandomized) study. Ignoring confounding in an observational study will often result in a "distorted" or incorrect estimate of the association or treatment effect. Interaction among variables, also known as effect modification, exists when the effect of 1 explanatory variable on the outcome depends on the particular level or value of another explanatory variable. Bias and confounding are common potential explanations for statistically significant associations between exposure and outcome when the true relationship is noncausal. Understanding interactions is vital to proper interpretation of treatment effects. These complex concepts should be consistently and appropriately considered whenever one is not only designing but also analyzing and interpreting data from a randomized trial or observational study.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Li, Ting
Over the last two decades, our understanding of the Milky Way has been improved thanks to large data sets arising from large-area digital sky surveys. The stellar halo is now known to be inhabited by a variety of spatial and kinematic stellar substructures, including stellar streams and stellar clouds, all of which are predicted by hierarchical Lambda Cold Dark Matter models of galaxy formation. In this dissertation, we first present the analysis of spectroscopic observations of individual stars from the two candidate structures discovered using an M-giant catalog from the Two Micron All-Sky Survey. The follow-up observations show that onemore » of the candidates is a genuine structure which might be associated with the Galactic Anticenter Stellar Structure, while the other one is a false detection due to the systematic photometric errors in the survey or dust extinction in low Galactic latitudes. We then presented the discovery of an excess of main sequence turn-off stars in the direction of the constellations of Eridanus and Phoenix from the first-year data of the Dark Energy Survey (DES) – a five-year, 5,000 deg2 optical imaging survey in the Southern Hemisphere. The Eridanus-Phoenix (EriPhe) overdensity is centered around l ~ 285° and b ~ -60° and the Poisson significance of the detection is at least 9σ. The EriPhe overdensity has a cloud-like morphology and the extent is at least ~ 4 kpc by ~ 3 kpc in projection, with a heliocentric distance of about d ~ 16 kpc. The EriPhe overdensity is morphologically similar to the previously-discovered Virgo overdensity and Hercules-Aquila cloud. These three overdensities lie along a polar plane separated by ~ 120° and may share a common origin. In addition to the scientific discoveries, we also present the work to improve the photometric calibration in DES using auxiliary calibration systems, since the photometric errors can cause false detection in first the halo substructure. We present a detailed description of the two auxiliary calibration systems built at Texas A&M University. We then discuss how the auxiliary systems in DES can be used to improve the photometric calibration of the systematic chromatic errors – source color-dependent systematic errors that are caused by variations in the wavelength dependence of the atmospheric transmission and the instrumental throughput.« less
NASA Astrophysics Data System (ADS)
Liang, Zhi-Chao; Birch, Aaron C.; Duvall, Thomas L., Jr.; Gizon, Laurent; Schou, Jesper
2017-05-01
Context. Time-distance helioseismology is one of the primary tools for studying the solar meridional circulation, especially in the lower convection zone. However, travel-time measurements of the subsurface meridional flow suffer from a variety of systematic errors, such as a center-to-limb variation and an offset due to the position angle (P-angle) uncertainty of solar images. It has been suggested that the center-to-limb variation can be removed by subtracting east-west from south-north travel-time measurements. This ad hoc method for the removal of the center-to-limb effect has been adopted widely but not tested for travel distances corresponding to the lower convection zone. Aims: We explore the effects of two major sources of the systematic errors, the P-angle error arising from the instrumental misalignment and the center-to-limb variation, on the acoustic travel-time measurements in the south-north direction. Methods: We apply the time-distance technique to contemporaneous medium-degree Dopplergrams produced by SOHO/MDI and SDO/HMI to obtain the travel-time difference caused by meridional circulation throughout the solar convection zone. The P-angle offset in MDI images is measured by cross-correlating MDI and HMI images. The travel-time measurements in the south-north and east-west directions are averaged over the same observation period (May 2010 to Apr. 2011) for the two data sets and then compared to examine the consistency of MDI and HMI travel times after applying the above-mentioned corrections. Results: The offsets in the south-north travel-time difference from MDI data induced by the P-angle error gradually diminish with increasing travel distance. However, these offsets become noisy for travel distances corresponding to waves that reach the base of the convection zone. This suggests that a careful treatment of the P-angle problem is required when studying a deep meridional flow. After correcting the P-angle and the removal of the center-to-limb effect, the travel-time measurements from MDI and HMI are consistent within the error bars for meridional circulation covering the entire convection zone. The fluctuations observed in both data sets are highly correlated and thus indicate their solar origin rather than an instrumental origin. Although our results demonstrate that the ad hoc correction is capable of reducing the wide discrepancy in the travel-time measurements from MDI and HMI, we cannot exclude the possibility that there exist other systematic effects acting on the two data sets in the same way.
NASA Astrophysics Data System (ADS)
Janowiecki, Steven; Cortese, Luca; Catinella, Barbara; Goodwin, Adelle J.
2018-05-01
We use galaxies from the Herschel Reference Survey to evaluate commonly used indirect predictors of cold gas masses. We calibrate predictions for cold neutral atomic and molecular gas using infrared dust emission and gas depletion time methods that are self-consistent and have ˜20 per cent accuracy (with the highest accuracy in the prediction of total cold gas mass). However, modest systematic residual dependences are found in all calibrations that depend on the partition between molecular and atomic gas, and can over/underpredict gas masses by up to 0.3 dex. As expected, dust-based estimates are best at predicting the total gas mass while depletion time-based estimates are only able to predict the (star-forming) molecular gas mass. Additionally, we advise caution when applying these predictions to high-z galaxies, as significant (0.5 dex or more) errors can arise when incorrect assumptions are made about the dominant gas phase. Any scaling relations derived using predicted gas masses may be more closely related to the calibrations used than to the actual galaxies observed.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Songaila, A.; Cowie, L. L., E-mail: acowie@ifa.hawaii.edu
2014-10-01
The unequivocal demonstration of temporal or spatial variability in a fundamental constant of nature would be of enormous significance. Recent attempts to measure the variability of the fine-structure constant α over cosmological time, using high-resolution spectra of high-redshift quasars observed with 10 m class telescopes, have produced conflicting results. We use the many multiplet (MM) method with Mg II and Fe II lines on very high signal-to-noise, high-resolution (R = 72, 000) Keck HIRES spectra of eight narrow quasar absorption systems. We consider both systematic uncertainties in spectrograph wavelength calibration and also velocity offsets introduced by complex velocity structure inmore » even apparently simple and weak narrow lines and analyze their effect on claimed variations in α. We find no significant change in α, Δα/α = (0.43 ± 0.34) × 10{sup –5}, in the redshift range z = 0.7-1.5, where this includes both statistical and systematic errors. We also show that the scatter in measurements of Δα/α arising from absorption line structure can be considerably larger than assigned statistical errors even for apparently simple and narrow absorption systems. We find a null result of Δα/α = (– 0.59 ± 0.55) × 10{sup –5} in a system at z = 1.7382 using lines of Cr II, Zn II, and Mn II, whereas using Cr II and Zn II lines in a system at z = 1.6614 we find a systematic velocity trend that, if interpreted as a shift in α, would correspond to Δα/α = (1.88 ± 0.47) × 10{sup –5}, where both results include both statistical and systematic errors. This latter result is almost certainly caused by varying ionic abundances in subcomponents of the line: using Mn II, Ni II, and Cr II in the analysis changes the result to Δα/α = (– 0.47 ± 0.53) × 10{sup –5}. Combining the Mg II and Fe II results with estimates based on Mn II, Ni II, and Cr II gives Δα/α = (– 0.01 ± 0.26) × 10{sup –5}. We conclude that spectroscopic measurements of quasar absorption lines are not yet capable of unambiguously detecting variation in α using the MM method.« less
Pratte, Michael S.; Park, Young Eun; Rademaker, Rosanne L.; Tong, Frank
2016-01-01
If we view a visual scene that contains many objects, then momentarily close our eyes, some details persist while others seem to fade. Discrete models of visual working memory (VWM) assume that only a few items can be actively maintained in memory, beyond which pure guessing will emerge. Alternatively, continuous resource models assume that all items in a visual scene can be stored with some precision. Distinguishing between these competing models is challenging, however, as resource models that allow for stochastically variable precision (across items and trials) can produce error distributions that resemble random guessing behavior. Here, we evaluated the hypothesis that a major source of variability in VWM performance arises from systematic variation in precision across the stimuli themselves; such stimulus-specific variability can be incorporated into both discrete-capacity and variable-precision resource models. Participants viewed multiple oriented gratings, and then reported the orientation of a cued grating from memory. When modeling the overall distribution of VWM errors, we found that the variable-precision resource model outperformed the discrete model. However, VWM errors revealed a pronounced “oblique effect”, with larger errors for oblique than cardinal orientations. After this source of variability was incorporated into both models, we found that the discrete model provided a better account of VWM errors. Our results demonstrate that variable precision across the stimulus space can lead to an unwarranted advantage for resource models that assume stochastically variable precision. When these deterministic sources are adequately modeled, human working memory performance reveals evidence of a discrete capacity limit. PMID:28004957
Pratte, Michael S; Park, Young Eun; Rademaker, Rosanne L; Tong, Frank
2017-01-01
If we view a visual scene that contains many objects, then momentarily close our eyes, some details persist while others seem to fade. Discrete models of visual working memory (VWM) assume that only a few items can be actively maintained in memory, beyond which pure guessing will emerge. Alternatively, continuous resource models assume that all items in a visual scene can be stored with some precision. Distinguishing between these competing models is challenging, however, as resource models that allow for stochastically variable precision (across items and trials) can produce error distributions that resemble random guessing behavior. Here, we evaluated the hypothesis that a major source of variability in VWM performance arises from systematic variation in precision across the stimuli themselves; such stimulus-specific variability can be incorporated into both discrete-capacity and variable-precision resource models. Participants viewed multiple oriented gratings, and then reported the orientation of a cued grating from memory. When modeling the overall distribution of VWM errors, we found that the variable-precision resource model outperformed the discrete model. However, VWM errors revealed a pronounced "oblique effect," with larger errors for oblique than cardinal orientations. After this source of variability was incorporated into both models, we found that the discrete model provided a better account of VWM errors. Our results demonstrate that variable precision across the stimulus space can lead to an unwarranted advantage for resource models that assume stochastically variable precision. When these deterministic sources are adequately modeled, human working memory performance reveals evidence of a discrete capacity limit. (PsycINFO Database Record (c) 2016 APA, all rights reserved).
NASA Astrophysics Data System (ADS)
Stone, Dáithí A.; Hansen, Gerrit
2016-09-01
Despite being a well-established research field, the detection and attribution of observed climate change to anthropogenic forcing is not yet provided as a climate service. One reason for this is the lack of a methodology for performing tailored detection and attribution assessments on a rapid time scale. Here we develop such an approach, based on the translation of quantitative analysis into the "confidence" language employed in recent Assessment Reports of the Intergovernmental Panel on Climate Change. While its systematic nature necessarily ignores some nuances examined in detailed expert assessments, the approach nevertheless goes beyond most detection and attribution studies in considering contributors to building confidence such as errors in observational data products arising from sparse monitoring networks. When compared against recent expert assessments, the results of this approach closely match those of the existing assessments. Where there are small discrepancies, these variously reflect ambiguities in the details of what is being assessed, reveal nuances or limitations of the expert assessments, or indicate limitations of the accuracy of the sort of systematic approach employed here. Deployment of the method on 116 regional assessments of recent temperature and precipitation changes indicates that existing rules of thumb concerning the detectability of climate change ignore the full range of sources of uncertainty, most particularly the importance of adequate observational monitoring.
Reyes, Jeanette M; Xu, Yadong; Vizuete, William; Serre, Marc L
2017-01-01
The regulatory Community Multiscale Air Quality (CMAQ) model is a means to understanding the sources, concentrations and regulatory attainment of air pollutants within a model's domain. Substantial resources are allocated to the evaluation of model performance. The Regionalized Air quality Model Performance (RAMP) method introduced here explores novel ways of visualizing and evaluating CMAQ model performance and errors for daily Particulate Matter ≤ 2.5 micrometers (PM2.5) concentrations across the continental United States. The RAMP method performs a non-homogenous, non-linear, non-homoscedastic model performance evaluation at each CMAQ grid. This work demonstrates that CMAQ model performance, for a well-documented 2001 regulatory episode, is non-homogeneous across space/time. The RAMP correction of systematic errors outperforms other model evaluation methods as demonstrated by a 22.1% reduction in Mean Square Error compared to a constant domain wide correction. The RAMP method is able to accurately reproduce simulated performance with a correlation of r = 76.1%. Most of the error coming from CMAQ is random error with only a minority of error being systematic. Areas of high systematic error are collocated with areas of high random error, implying both error types originate from similar sources. Therefore, addressing underlying causes of systematic error will have the added benefit of also addressing underlying causes of random error.
Errors in radial velocity variance from Doppler wind lidar
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wang, H.; Barthelmie, R. J.; Doubrawa, P.
A high-fidelity lidar turbulence measurement technique relies on accurate estimates of radial velocity variance that are subject to both systematic and random errors determined by the autocorrelation function of radial velocity, the sampling rate, and the sampling duration. Our paper quantifies the effect of the volumetric averaging in lidar radial velocity measurements on the autocorrelation function and the dependence of the systematic and random errors on the sampling duration, using both statistically simulated and observed data. For current-generation scanning lidars and sampling durations of about 30 min and longer, during which the stationarity assumption is valid for atmospheric flows, themore » systematic error is negligible but the random error exceeds about 10%.« less
Errors in radial velocity variance from Doppler wind lidar
Wang, H.; Barthelmie, R. J.; Doubrawa, P.; ...
2016-08-29
A high-fidelity lidar turbulence measurement technique relies on accurate estimates of radial velocity variance that are subject to both systematic and random errors determined by the autocorrelation function of radial velocity, the sampling rate, and the sampling duration. Our paper quantifies the effect of the volumetric averaging in lidar radial velocity measurements on the autocorrelation function and the dependence of the systematic and random errors on the sampling duration, using both statistically simulated and observed data. For current-generation scanning lidars and sampling durations of about 30 min and longer, during which the stationarity assumption is valid for atmospheric flows, themore » systematic error is negligible but the random error exceeds about 10%.« less
Automated Comparative Auditing of NCIT Genomic Roles Using NCBI
Cohen, Barry; Oren, Marc; Min, Hua; Perl, Yehoshua; Halper, Michael
2008-01-01
Biomedical research has identified many human genes and various knowledge about them. The National Cancer Institute Thesaurus (NCIT) represents such knowledge as concepts and roles (relationships). Due to the rapid advances in this field, it is to be expected that the NCIT’s Gene hierarchy will contain role errors. A comparative methodology to audit the Gene hierarchy with the use of the National Center for Biotechnology Information’s (NCBI’s) Entrez Gene database is presented. The two knowledge sources are accessed via a pair of Web crawlers to ensure up-to-date data. Our algorithms then compare the knowledge gathered from each, identify discrepancies that represent probable errors, and suggest corrective actions. The primary focus is on two kinds of gene-roles: (1) the chromosomal locations of genes, and (2) the biological processes in which genes plays a role. Regarding chromosomal locations, the discrepancies revealed are striking and systematic, suggesting a structurally common origin. In regard to the biological processes, difficulties arise because genes frequently play roles in multiple processes, and processes may have many designations (such as synonymous terms). Our algorithms make use of the roles defined in the NCIT Biological Process hierarchy to uncover many probable gene-role errors in the NCIT. These results show that automated comparative auditing is a promising technique that can identify a large number of probable errors and corrections for them in a terminological genomic knowledge repository, thus facilitating its overall maintenance. PMID:18486558
Assessing colour-dependent occupation statistics inferred from galaxy group catalogues
NASA Astrophysics Data System (ADS)
Campbell, Duncan; van den Bosch, Frank C.; Hearin, Andrew; Padmanabhan, Nikhil; Berlind, Andreas; Mo, H. J.; Tinker, Jeremy; Yang, Xiaohu
2015-09-01
We investigate the ability of current implementations of galaxy group finders to recover colour-dependent halo occupation statistics. To test the fidelity of group catalogue inferred statistics, we run three different group finders used in the literature over a mock that includes galaxy colours in a realistic manner. Overall, the resulting mock group catalogues are remarkably similar, and most colour-dependent statistics are recovered with reasonable accuracy. However, it is also clear that certain systematic errors arise as a consequence of correlated errors in group membership determination, central/satellite designation, and halo mass assignment. We introduce a new statistic, the halo transition probability (HTP), which captures the combined impact of all these errors. As a rule of thumb, errors tend to equalize the properties of distinct galaxy populations (i.e. red versus blue galaxies or centrals versus satellites), and to result in inferred occupation statistics that are more accurate for red galaxies than for blue galaxies. A statistic that is particularly poorly recovered from the group catalogues is the red fraction of central galaxies as a function of halo mass. Group finders do a good job in recovering galactic conformity, but also have a tendency to introduce weak conformity when none is present. We conclude that proper inference of colour-dependent statistics from group catalogues is best achieved using forward modelling (i.e. running group finders over mock data) or by implementing a correction scheme based on the HTP, as long as the latter is not too strongly model dependent.
A procedure for the significance testing of unmodeled errors in GNSS observations
NASA Astrophysics Data System (ADS)
Li, Bofeng; Zhang, Zhetao; Shen, Yunzhong; Yang, Ling
2018-01-01
It is a crucial task to establish a precise mathematical model for global navigation satellite system (GNSS) observations in precise positioning. Due to the spatiotemporal complexity of, and limited knowledge on, systematic errors in GNSS observations, some residual systematic errors would inevitably remain even after corrected with empirical model and parameterization. These residual systematic errors are referred to as unmodeled errors. However, most of the existing studies mainly focus on handling the systematic errors that can be properly modeled and then simply ignore the unmodeled errors that may actually exist. To further improve the accuracy and reliability of GNSS applications, such unmodeled errors must be handled especially when they are significant. Therefore, a very first question is how to statistically validate the significance of unmodeled errors. In this research, we will propose a procedure to examine the significance of these unmodeled errors by the combined use of the hypothesis tests. With this testing procedure, three components of unmodeled errors, i.e., the nonstationary signal, stationary signal and white noise, are identified. The procedure is tested by using simulated data and real BeiDou datasets with varying error sources. The results show that the unmodeled errors can be discriminated by our procedure with approximately 90% confidence. The efficiency of the proposed procedure is further reassured by applying the time-domain Allan variance analysis and frequency-domain fast Fourier transform. In summary, the spatiotemporally correlated unmodeled errors are commonly existent in GNSS observations and mainly governed by the residual atmospheric biases and multipath. Their patterns may also be impacted by the receiver.
Rationality in collective decision-making by ant colonies.
Edwards, Susan C; Pratt, Stephen C
2009-10-22
Economic models of animal behaviour assume that decision-makers are rational, meaning that they assess options according to intrinsic fitness value and not by comparison with available alternatives. This expectation is frequently violated, but the significance of irrational behaviour remains controversial. One possibility is that irrationality arises from cognitive constraints that necessitate short cuts like comparative evaluation. If so, the study of whether and when irrationality occurs can illuminate cognitive mechanisms. We applied this logic in a novel setting: the collective decisions of insect societies. We tested for irrationality in colonies of Temnothorax ants choosing between two nest sites that varied in multiple attributes, such that neither site was clearly superior. In similar situations, individual animals show irrational changes in preference when a third relatively unattractive option is introduced. In contrast, we found no such effect in colonies. We suggest that immunity to irrationality in this case may result from the ants' decentralized decision mechanism. A colony's choice does not depend on site comparison by individuals, but instead self-organizes from the interactions of multiple ants, most of which are aware of only a single site. This strategy may filter out comparative effects, preventing systematic errors that would otherwise arise from the cognitive limitations of individuals.
The Binding of Learning to Action in Motor Adaptation
Gonzalez Castro, Luis Nicolas; Monsen, Craig Bryant; Smith, Maurice A.
2011-01-01
In motor tasks, errors between planned and actual movements generally result in adaptive changes which reduce the occurrence of similar errors in the future. It has commonly been assumed that the motor adaptation arising from an error occurring on a particular movement is specifically associated with the motion that was planned. Here we show that this is not the case. Instead, we demonstrate the binding of the adaptation arising from an error on a particular trial to the motion experienced on that same trial. The formation of this association means that future movements planned to resemble the motion experienced on a given trial benefit maximally from the adaptation arising from it. This reflects the idea that actual rather than planned motions are assigned ‘credit’ for motor errors because, in a computational sense, the maximal adaptive response would be associated with the condition credited with the error. We studied this process by examining the patterns of generalization associated with motor adaptation to novel dynamic environments during reaching arm movements in humans. We found that these patterns consistently matched those predicted by adaptation associated with the actual rather than the planned motion, with maximal generalization observed where actual motions were clustered. We followed up these findings by showing that a novel training procedure designed to leverage this newfound understanding of the binding of learning to action, can improve adaptation rates by greater than 50%. Our results provide a mechanistic framework for understanding the effects of partial assistance and error augmentation during neurologic rehabilitation, and they suggest ways to optimize their use. PMID:21731476
NASA Astrophysics Data System (ADS)
He, Yingwei; Li, Ping; Feng, Guojin; Cheng, Li; Wang, Yu; Wu, Houping; Liu, Zilong; Zheng, Chundi; Sha, Dingguo
2010-11-01
For measuring large-aperture optical system transmittance, a novel sub-aperture scanning machine with double-rotating arms (SSMDA) was designed to obtain sub-aperture beam spot. Optical system full-aperture transmittance measurements can be achieved by applying sub-aperture beam spot scanning technology. The mathematical model of the SSMDA based on a homogeneous coordinate transformation matrix is established to develop a detailed methodology for analyzing the beam spot scanning errors. The error analysis methodology considers two fundamental sources of scanning errors, namely (1) the length systematic errors and (2) the rotational systematic errors. As the systematic errors of the parameters are given beforehand, computational results of scanning errors are between -0.007~0.028mm while scanning radius is not lager than 400.000mm. The results offer theoretical and data basis to the research on transmission characteristics of large optical system.
The Public Understanding of Error in Educational Assessment
ERIC Educational Resources Information Center
Gardner, John
2013-01-01
Evidence from recent research suggests that in the UK the public perception of errors in national examinations is that they are simply mistakes; events that are preventable. This perception predominates over the more sophisticated technical view that errors arise from many sources and create an inevitable variability in assessment outcomes. The…
NASA Technical Reports Server (NTRS)
Ricks, Douglas W.
1993-01-01
There are a number of sources of scattering in binary optics: etch depth errors, line edge errors, quantization errors, roughness, and the binary approximation to the ideal surface. These sources of scattering can be systematic (deterministic) or random. In this paper, scattering formulas for both systematic and random errors are derived using Fourier optics. These formulas can be used to explain the results of scattering measurements and computer simulations.
Systematic errors of EIT systems determined by easily-scalable resistive phantoms.
Hahn, G; Just, A; Dittmar, J; Hellige, G
2008-06-01
We present a simple method to determine systematic errors that will occur in the measurements by EIT systems. The approach is based on very simple scalable resistive phantoms for EIT systems using a 16 electrode adjacent drive pattern. The output voltage of the phantoms is constant for all combinations of current injection and voltage measurements and the trans-impedance of each phantom is determined by only one component. It can be chosen independently from the input and output impedance, which can be set in order to simulate measurements on the human thorax. Additional serial adapters allow investigation of the influence of the contact impedance at the electrodes on resulting errors. Since real errors depend on the dynamic properties of an EIT system, the following parameters are accessible: crosstalk, the absolute error of each driving/sensing channel and the signal to noise ratio in each channel. Measurements were performed on a Goe-MF II EIT system under four different simulated operational conditions. We found that systematic measurement errors always exceeded the error level of stochastic noise since the Goe-MF II system had been optimized for a sufficient signal to noise ratio but not for accuracy. In time difference imaging and functional EIT (f-EIT) systematic errors are reduced to a minimum by dividing the raw data by reference data. This is not the case in absolute EIT (a-EIT) where the resistivity of the examined object is determined on an absolute scale. We conclude that a reduction of systematic errors has to be one major goal in future system design.
Frequency of pediatric medication administration errors and contributing factors.
Ozkan, Suzan; Kocaman, Gulseren; Ozturk, Candan; Seren, Seyda
2011-01-01
This study examined the frequency of pediatric medication administration errors and contributing factors. This research used the undisguised observation method and Critical Incident Technique. Errors and contributing factors were classified through the Organizational Accident Model. Errors were made in 36.5% of the 2344 doses that were observed. The most frequent errors were those associated with administration at the wrong time. According to the results of this study, errors arise from problems within the system.
Complete Systematic Error Model of SSR for Sensor Registration in ATC Surveillance Networks
Besada, Juan A.
2017-01-01
In this paper, a complete and rigorous mathematical model for secondary surveillance radar systematic errors (biases) is developed. The model takes into account the physical effects systematically affecting the measurement processes. The azimuth biases are calculated from the physical error of the antenna calibration and the errors of the angle determination dispositive. Distance bias is calculated from the delay of the signal produced by the refractivity index of the atmosphere, and from clock errors, while the altitude bias is calculated taking into account the atmosphere conditions (pressure and temperature). It will be shown, using simulated and real data, that adapting a classical bias estimation process to use the complete parametrized model results in improved accuracy in the bias estimation. PMID:28934157
Sources of variability and systematic error in mouse timing behavior.
Gallistel, C R; King, Adam; McDonald, Robert
2004-01-01
In the peak procedure, starts and stops in responding bracket the target time at which food is expected. The variability in start and stop times is proportional to the target time (scalar variability), as is the systematic error in the mean center (scalar error). The authors investigated the source of the error and the variability, using head poking in the mouse, with target intervals of 5 s, 15 s, and 45 s, in the standard procedure, and in a variant with 3 different target intervals at 3 different locations in a single trial. The authors conclude that the systematic error is due to the asymmetric location of start and stop decision criteria, and the scalar variability derives primarily from sources other than memory.
Error analysis and system optimization of non-null aspheric testing system
NASA Astrophysics Data System (ADS)
Luo, Yongjie; Yang, Yongying; Liu, Dong; Tian, Chao; Zhuo, Yongmo
2010-10-01
A non-null aspheric testing system, which employs partial null lens (PNL for short) and reverse iterative optimization reconstruction (ROR for short) technique, is proposed in this paper. Based on system modeling in ray tracing software, the parameter of each optical element is optimized and this makes system modeling more precise. Systematic error of non-null aspheric testing system is analyzed and can be categorized into two types, the error due to surface parameters of PNL in the system modeling and the rest from non-null interferometer by the approach of error storage subtraction. Experimental results show that, after systematic error is removed from testing result of non-null aspheric testing system, the aspheric surface is precisely reconstructed by ROR technique and the consideration of systematic error greatly increase the test accuracy of non-null aspheric testing system.
NASA Technical Reports Server (NTRS)
Koch, S. E.; Skillman, W. C.; Kocin, P. J.; Wetzel, P. J.; Brill, K. F.
1985-01-01
The synoptic scale performance characteristics of MASS 2.0 are determined by comparing filtered 12-24 hr model forecasts to same-case forecasts made by the National Meteorological Center's synoptic-scale Limited-area Fine Mesh model. Characteristics of the two systems are contrasted, and the analysis methodology used to determine statistical skill scores and systematic errors is described. The overall relative performance of the two models in the sample is documented, and important systematic errors uncovered are presented.
Error Estimates for Numerical Integration Rules
ERIC Educational Resources Information Center
Mercer, Peter R.
2005-01-01
The starting point for this discussion of error estimates is the fact that integrals that arise in Fourier series have properties that can be used to get improved bounds. This idea is extended to more general situations.
A new systematic calibration method of ring laser gyroscope inertial navigation system
NASA Astrophysics Data System (ADS)
Wei, Guo; Gao, Chunfeng; Wang, Qi; Wang, Qun; Xiong, Zhenyu; Long, Xingwu
2016-10-01
Inertial navigation system has been the core component of both military and civil navigation systems. Before the INS is put into application, it is supposed to be calibrated in the laboratory in order to compensate repeatability error caused by manufacturing. Discrete calibration method cannot fulfill requirements of high-accurate calibration of the mechanically dithered ring laser gyroscope navigation system with shock absorbers. This paper has analyzed theories of error inspiration and separation in detail and presented a new systematic calibration method for ring laser gyroscope inertial navigation system. Error models and equations of calibrated Inertial Measurement Unit are given. Then proper rotation arrangement orders are depicted in order to establish the linear relationships between the change of velocity errors and calibrated parameter errors. Experiments have been set up to compare the systematic errors calculated by filtering calibration result with those obtained by discrete calibration result. The largest position error and velocity error of filtering calibration result are only 0.18 miles and 0.26m/s compared with 2 miles and 1.46m/s of discrete calibration result. These results have validated the new systematic calibration method and proved its importance for optimal design and accuracy improvement of calibration of mechanically dithered ring laser gyroscope inertial navigation system.
Measuring Systematic Error with Curve Fits
ERIC Educational Resources Information Center
Rupright, Mark E.
2011-01-01
Systematic errors are often unavoidable in the introductory physics laboratory. As has been demonstrated in many papers in this journal, such errors can present a fundamental problem for data analysis, particularly when comparing the data to a given model. In this paper I give three examples in which my students use popular curve-fitting software…
Systematic Error Modeling and Bias Estimation
Zhang, Feihu; Knoll, Alois
2016-01-01
This paper analyzes the statistic properties of the systematic error in terms of range and bearing during the transformation process. Furthermore, we rely on a weighted nonlinear least square method to calculate the biases based on the proposed models. The results show the high performance of the proposed approach for error modeling and bias estimation. PMID:27213386
On the apparent velocity of integrated sunlight. I - 1983-1985
NASA Technical Reports Server (NTRS)
Deming, Drake; Espenak, Fred; Jennings, Donald E.; Brault, James W.; Wagner, Jeremy
1987-01-01
Frequency measurements for the Delta V = 2 transitions of CO in the integrated light spectrum of the sun are presented. The nature and magnitude of systematic errors which typically arise in absolute velocity measurements of integrated sunlight are explored in some detail, and measurements believed accurate at the level of about 5 m/s or less are presented. It is found that the integrated light velocity varies by about 3 m/s or less over a one-day period. Over the long term, the data indicate an increasing blue-shift in these weak infrared lines amounting to 30 m/s from 1983 to 1985. The sense of the drift is consistent with a lessening in the magnetic inhibition of granular convection at solar minimum. Such an effect has implications for the spectroscopic detectability of planetary-mass companions to solar-type stars.
Factors affecting measurement of channel thickness in asymmetrical flow field-flow fractionation.
Dou, Haiyang; Jung, Euo Chang; Lee, Seungho
2015-05-08
Asymmetrical flow field-flow fractionation (AF4) has been considered to be a useful tool for simultaneous separation and characterization of polydisperse macromolecules or colloidal nanoparticles. AF4 analysis requires the knowledge of the channel thickness (w), which is usually measured by injecting a standard with known diffusion coefficient (D) or hydrodynamic diameter (dh). An accurate w determination is a challenge due to its uncertainties arising from the membrane's compressibility, which may vary with experimental condition. In the present study, influence of factors including the size and type of the standard on the measurement of w was systematically investigated. The results revealed that steric effect and the particles-membrane interaction by van der Waals or electrostatic force may result in an error in w measurement. Copyright © 2015 Elsevier B.V. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Yu, Juan; Beltran, Chris J., E-mail: beltran.chris@mayo.edu; Herman, Michael G.
Purpose: To quantitatively and systematically assess dosimetric effects induced by spot positioning error as a function of spot spacing (SS) on intensity-modulated proton therapy (IMPT) plan quality and to facilitate evaluation of safety tolerance limits on spot position. Methods: Spot position errors (PE) ranging from 1 to 2 mm were simulated. Simple plans were created on a water phantom, and IMPT plans were calculated on two pediatric patients with a brain tumor of 28 and 3 cc, respectively, using a commercial planning system. For the phantom, a uniform dose was delivered to targets located at different depths from 10 tomore » 20 cm with various field sizes from 2{sup 2} to 15{sup 2} cm{sup 2}. Two nominal spot sizes, 4.0 and 6.6 mm of 1 σ in water at isocenter, were used for treatment planning. The SS ranged from 0.5 σ to 1.5 σ, which is 2–6 mm for the small spot size and 3.3–9.9 mm for the large spot size. Various perturbation scenarios of a single spot error and systematic and random multiple spot errors were studied. To quantify the dosimetric effects, percent dose error (PDE) depth profiles and the value of percent dose error at the maximum dose difference (PDE [ΔDmax]) were used for evaluation. Results: A pair of hot and cold spots was created per spot shift. PDE[ΔDmax] is found to be a complex function of PE, SS, spot size, depth, and global spot distribution that can be well defined in simple models. For volumetric targets, the PDE [ΔDmax] is not noticeably affected by the change of field size or target volume within the studied ranges. In general, reducing SS decreased the dose error. For the facility studied, given a single spot error with a PE of 1.2 mm and for both spot sizes, a SS of 1σ resulted in a 2% maximum dose error; a SS larger than 1.25 σ substantially increased the dose error and its sensitivity to PE. A similar trend was observed in multiple spot errors (both systematic and random errors). Systematic PE can lead to noticeable hot spots along the field edges, which may be near critical structures. However, random PE showed minimal dose error. Conclusions: Dose error dependence for PE was quantitatively and systematically characterized and an analytic tool was built to simulate systematic and random errors for patient-specific IMPT. This information facilitates the determination of facility specific spot position error thresholds.« less
Hendry, Kathryn; Ownsworth, Tamara; Beadle, Elizabeth; Chevignard, Mathilde P.; Fleming, Jennifer; Griffin, Janelle; Shum, David H. K.
2016-01-01
People with severe traumatic brain injury (TBI) often make errors on everyday tasks that compromise their safety and independence. Such errors potentially arise from the breakdown or failure of multiple cognitive processes. This study aimed to investigate cognitive deficits underlying error behavior on a home-based version of the Cooking Task (HBCT) following TBI. Participants included 45 adults (9 females, 36 males) with severe TBI aged 18–64 years (M = 37.91, SD = 13.43). Participants were administered the HBCT in their home kitchens, with audiovisual recordings taken to enable scoring of total errors and error subtypes (Omissions, Additions, Estimations, Substitutions, Commentary/Questions, Dangerous Behavior, Goal Achievement). Participants also completed a battery of neuropsychological tests, including the Trail Making Test, Hopkins Verbal Learning Test-Revised, Digit Span, Zoo Map test, Modified Stroop Test, and Hayling Sentence Completion Test. After controlling for cooking experience, greater Omissions and Estimation errors, lack of goal achievement, and longer completion time were significantly associated with poorer attention, memory, and executive functioning. These findings indicate that errors on naturalistic tasks arise from deficits in multiple cognitive domains. Assessment of error behavior in a real life setting provides insight into individuals' functional abilities which can guide rehabilitation planning and lifestyle support. PMID:27790099
2017-01-01
Unique Molecular Identifiers (UMIs) are random oligonucleotide barcodes that are increasingly used in high-throughput sequencing experiments. Through a UMI, identical copies arising from distinct molecules can be distinguished from those arising through PCR amplification of the same molecule. However, bioinformatic methods to leverage the information from UMIs have yet to be formalized. In particular, sequencing errors in the UMI sequence are often ignored or else resolved in an ad hoc manner. We show that errors in the UMI sequence are common and introduce network-based methods to account for these errors when identifying PCR duplicates. Using these methods, we demonstrate improved quantification accuracy both under simulated conditions and real iCLIP and single-cell RNA-seq data sets. Reproducibility between iCLIP replicates and single-cell RNA-seq clustering are both improved using our proposed network-based method, demonstrating the value of properly accounting for errors in UMIs. These methods are implemented in the open source UMI-tools software package. PMID:28100584
Temperature-dependent errors in nuclear lattice simulations
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lee, Dean; Thomson, Richard
2007-06-15
We study the temperature dependence of discretization errors in nuclear lattice simulations. We find that for systems with strong attractive interactions the predominant error arises from the breaking of Galilean invariance. We propose a local 'well-tempered' lattice action which eliminates much of this error. The well-tempered action can be readily implemented in lattice simulations for nuclear systems as well as cold atomic Fermi systems.
Addressing Systematic Errors in Correlation Tracking on HMI Magnetograms
NASA Astrophysics Data System (ADS)
Mahajan, Sushant S.; Hathaway, David H.; Munoz-Jaramillo, Andres; Martens, Petrus C.
2017-08-01
Correlation tracking in solar magnetograms is an effective method to measure the differential rotation and meridional flow on the solar surface. However, since the tracking accuracy required to successfully measure meridional flow is very high, small systematic errors have a noticeable impact on measured meridional flow profiles. Additionally, the uncertainties of this kind of measurements have been historically underestimated, leading to controversy regarding flow profiles at high latitudes extracted from measurements which are unreliable near the solar limb.Here we present a set of systematic errors we have identified (and potential solutions), including bias caused by physical pixel sizes, center-to-limb systematics, and discrepancies between measurements performed using different time intervals. We have developed numerical techniques to get rid of these systematic errors and in the process improve the accuracy of the measurements by an order of magnitude.We also present a detailed analysis of uncertainties in these measurements using synthetic magnetograms and the quantification of an upper limit below which meridional flow measurements cannot be trusted as a function of latitude.
Precision of natural satellite ephemerides from observations of different types
NASA Astrophysics Data System (ADS)
Emelyanov, N. V.
2017-08-01
Currently, various types of observations of natural planetary satellites are used to refine their ephemerides. A new type of measurement - determining the instants of apparent satellite encounters - has recently been proposed by Morgado and co-workers. The problem that arises is which type of measurement to choose in order to obtain an ephemeris precision that is as high as possible. The answer can be obtained only by modelling the entire process: observations, obtaining the measured values, refining the satellite motion parameters, and generating the ephemeris. The explicit dependence of the ephemeris precision on observational accuracy as well as on the type of observations is unknown. In this paper, such a dependence is investigated using the Monte Carlo statistical method. The relationship between the ephemeris precision for different types of observations is then assessed. The possibility of using the instants of apparent satellite encounters to obtain an ephemeris is investigated. A method is proposed that can be used to fit the satellite orbital parameters to this type of measurement. It is shown that, in the absence of systematic scale errors in the CCD frame, the use of the instants of apparent encounters leads to less precise ephemerides. However, in the presence of significant scale errors, which is often the case, this type of measurement becomes effective because the instants of apparent satellite encounters do not depend on scale errors.
Physical fault tolerance of nanoelectronics.
Szkopek, Thomas; Roychowdhury, Vwani P; Antoniadis, Dimitri A; Damoulakis, John N
2011-04-29
The error rate in complementary transistor circuits is suppressed exponentially in electron number, arising from an intrinsic physical implementation of fault-tolerant error correction. Contrariwise, explicit assembly of gates into the most efficient known fault-tolerant architecture is characterized by a subexponential suppression of error rate with electron number, and incurs significant overhead in wiring and complexity. We conclude that it is more efficient to prevent logical errors with physical fault tolerance than to correct logical errors with fault-tolerant architecture.
Casas, Francisco J; Ortiz, David; Villa, Enrique; Cano, Juan L; Cagigas, Jaime; Pérez, Ana R; Aja, Beatriz; Terán, J Vicente; de la Fuente, Luisa; Artal, Eduardo; Hoyland, Roger; Génova-Santos, Ricardo
2015-08-05
This paper presents preliminary polarization measurements and systematic-error characterization of the Thirty Gigahertz Instrument receiver developed for the QUIJOTE experiment. The instrument has been designed to measure the polarization of Cosmic Microwave Background radiation from the sky, obtaining the Q, U, and I Stokes parameters of the incoming signal simultaneously. Two kinds of linearly polarized input signals have been used as excitations in the polarimeter measurement tests in the laboratory; these show consistent results in terms of the Stokes parameters obtained. A measurement-based systematic-error characterization technique has been used in order to determine the possible sources of instrumental errors and to assist in the polarimeter calibration process.
Talbot, Clifford B; Lagarto, João; Warren, Sean; Neil, Mark A A; French, Paul M W; Dunsby, Chris
2015-09-01
A correction is proposed to the Delta function convolution method (DFCM) for fitting a multiexponential decay model to time-resolved fluorescence decay data using a monoexponential reference fluorophore. A theoretical analysis of the discretised DFCM multiexponential decay function shows the presence an extra exponential decay term with the same lifetime as the reference fluorophore that we denote as the residual reference component. This extra decay component arises as a result of the discretised convolution of one of the two terms in the modified model function required by the DFCM. The effect of the residual reference component becomes more pronounced when the fluorescence lifetime of the reference is longer than all of the individual components of the specimen under inspection and when the temporal sampling interval is not negligible compared to the quantity (τR (-1) - τ(-1))(-1), where τR and τ are the fluorescence lifetimes of the reference and the specimen respectively. It is shown that the unwanted residual reference component results in systematic errors when fitting simulated data and that these errors are not present when the proposed correction is applied. The correction is also verified using real data obtained from experiment.
Assessment of Systematic Measurement Errors for Acoustic Travel-Time Tomography of the Atmosphere
2013-01-01
measurements include assess- ment of the time delays in electronic circuits and mechanical hardware (e.g., drivers and microphones) of a tomography array ...hardware and electronic circuits of the tomography array and errors in synchronization of the transmitted and recorded signals. For example, if...coordinates can be as large as 30 cm. These errors are equivalent to the systematic errors in the travel times of 0.9 ms. Third, loudspeakers which are used
Partitioning error components for accuracy-assessment of near-neighbor methods of imputation
Albert R. Stage; Nicholas L. Crookston
2007-01-01
Imputation is applied for two quite different purposes: to supply missing data to complete a data set for subsequent modeling analyses or to estimate subpopulation totals. Error properties of the imputed values have different effects in these two contexts. We partition errors of imputation derived from similar observation units as arising from three sources:...
Handling Errors as They Arise in Whole-Class Interactions
ERIC Educational Resources Information Center
Ingram, Jenni; Pitt, Andrea; Baldry, Fay
2015-01-01
There has been a long history of research into errors and their role in the teaching and learning of mathematics. This research has led to a change to pedagogical recommendations from avoiding errors to explicitly using them in lessons. In this study, 22 mathematics lessons were video-recorded and transcribed. A conversation analytic (CA) approach…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Petyuk, Vladislav A.; Mayampurath, Anoop M.; Monroe, Matthew E.
2009-12-16
Hybrid two-stage mass spectrometers capable of both highly accurate mass measurement and MS/MS fragmentation have become widely available in recent years and have allowed for sig-nificantly better discrimination between true and false MS/MS pep-tide identifications by applying relatively narrow windows for maxi-mum allowable deviations for parent ion mass measurements. To fully gain the advantage of highly accurate parent ion mass meas-urements, it is important to limit systematic mass measurement errors. The DtaRefinery software tool can correct systematic errors in parent ion masses by reading a set of fragmentation spectra, searching for MS/MS peptide identifications, then fitting a model that canmore » estimate systematic errors, and removing them. This results in a new fragmentation spectrum file with updated parent ion masses.« less
Stone, Daithi A.; Hansen, Gerrit
2015-11-21
Despite being a well-established research field, the detection and attribution of observed climate change to anthropogenic forcing is not yet provided as a climate service. One reason for this is the lack of a methodology for performing tailored detection and attribution assessments on a rapid time scale. Here we develop such an approach, based on the translation of quantitative analysis into the “confidence” language employed in recent Assessment Reports of the Intergovernmental Panel on Climate Change. While its systematic nature necessarily ignores some nuances examined in detailed expert assessments, the approach nevertheless goes beyond most detection and attribution studies inmore » considering contributors to building confidence such as errors in observational data products arising from sparse monitoring networks. When compared against recent expert assessments, the results of this approach closely match those of the existing assessments. Where there are small discrepancies, these variously reflect ambiguities in the details of what is being assessed, reveal nuances or limitations of the expert assessments, or indicate limitations of the accuracy of the sort of systematic approach employed here. Deployment of the method on 116 regional assessments of recent temperature and precipitation changes indicates that existing rules of thumb concerning the detectability of climate change ignore the full range of sources of uncertainty, most particularly the importance of adequate observational monitoring.« less
Testing the gravitational inverse-square law at centimeter scales
NASA Astrophysics Data System (ADS)
Bonicalzi, Ricco
Many attempts to unify gravity with the Standard Model entail a gravitational inverse-square-law violation (ISLV) at some low level. This dissertation reports on the initial phase of a torsion-pendulum null experiment searching for such a violation in the interaction between two macroscopic bodies with a characteristic separation of 12 cm. Central to the experimental design is the special configuration of the mass distributions of both the pendulum and source mass to provide high-sensitivity to the horizontal gradient of the Laplacian of the interaction potential (a signature of ISLV), while strongly suppressing coupling through Newtonian gravity. Specifically, this design ensures that gravitational systematic effects arise only at second order in the fabrication errors of the pendulum and source mass. A key aspect of this work is the choice of the second-harmonic amplitude of pendulum oscillation as the torque observable, instead of the traditional oscillation frequency. This relatively recent torsion-pendulum method is markedly less sensitive to changes in torsion-fiber temperature and enables the ambient-temperature instrumentation of the initial phase to achieve necessary noise performance without heroic efforts to stabilize temperature. As details of the second-harmonic method have not yet been published, the presentation here dwells on a number of subtleties involved in analyzing the data. Experimental results are reported assuming a Yukawa-type interaction anomaly, where a is the strength of the Yukawa term relative to Newtonian gravity. A preliminary set of 34 data runs, each around a day in duration, produced a value of alpha = (-6.3 +/- 7.5) x 10-5. In the absence of significant systematic effects, even this interim result would have placed tighter bounds on ISLV than previously appearing in the literature. Unfortunately, an accelerated Department of Energy deadline for demolition of our Hanford laboratory facility compelled a shift of focus to the principal phase of this experiment before resolving two apparently marginal, but significant sources of systematic error. These and resolved systematic effects are discussed in the context of the second-harmonic method.
Evaluating Precipitation from Orbital Data Products of TRMM and GPM over the Indian Subcontinent
NASA Astrophysics Data System (ADS)
Jayaluxmi, I.; Kumar, D. N.
2015-12-01
The rapidly growing records of microwave based precipitation data made available from various earth observation satellites have instigated a pressing need towards evaluating the associated uncertainty which arise from different sources such as retrieval error, spatial/temporal sampling error and sensor dependent error. Pertaining to microwave remote sensing, most of the studies in literature focus on gridded data products, fewer studies exist on evaluating the uncertainty inherent in orbital data products. Evaluation of the latter are essential as they potentially cause large uncertainties during real time flood forecasting studies especially at the watershed scale. The present study evaluates the uncertainty of precipitation data derived from the orbital data products of the Tropical Rainfall Measuring Mission (TRMM) satellite namely the 2A12, 2A25 and 2B31 products. Case study results over the flood prone basin of Mahanadi, India, are analyzed for precipitation uncertainty through these three facets viz., a) Uncertainty quantification using the volumetric metrics from the contingency table [Aghakouchak and Mehran 2014] b) Error characterization using additive and multiplicative error models c) Error decomposition to identify systematic and random errors d) Comparative assessment with the orbital data from GPM mission. The homoscedastic random errors from multiplicative error models justify a better representation of precipitation estimates by the 2A12 algorithm. It can be concluded that although the radiometer derived 2A12 precipitation data is known to suffer from many sources of uncertainties, spatial analysis over the case study region of India testifies that they are in excellent agreement with the reference estimates for the data period considered [Indu and Kumar 2015]. References A. AghaKouchak and A. Mehran (2014), Extended contingency table: Performance metrics for satellite observations and climate model simulations, Water Resources Research, vol. 49, 7144-7149; J. Indu and D. Nagesh Kumar (2015), Evaluation of Precipitation Retrievals from Orbital Data Products of TRMM over a Subtropical basin in India, IEEE Transactions on Geoscience and Remote Sensing, in press, doi: 10.1109/TGRS.2015.2440338.
NASA Astrophysics Data System (ADS)
Hu, Qing-Qing; Freier, Christian; Leykauf, Bastian; Schkolnik, Vladimir; Yang, Jun; Krutzik, Markus; Peters, Achim
2017-09-01
Precisely evaluating the systematic error induced by the quadratic Zeeman effect is important for developing atom interferometer gravimeters aiming at an accuracy in the μ Gal regime (1 μ Gal =10-8m /s2 ≈10-9g ). This paper reports on the experimental investigation of Raman spectroscopy-based magnetic field measurements and the evaluation of the systematic error in the gravimetric atom interferometer (GAIN) due to quadratic Zeeman effect. We discuss Raman duration and frequency step-size-dependent magnetic field measurement uncertainty, present vector light shift and tensor light shift induced magnetic field measurement offset, and map the absolute magnetic field inside the interferometer chamber of GAIN with an uncertainty of 0.72 nT and a spatial resolution of 12.8 mm. We evaluate the quadratic Zeeman-effect-induced gravity measurement error in GAIN as 2.04 μ Gal . The methods shown in this paper are important for precisely mapping the absolute magnetic field in vacuum and reducing the quadratic Zeeman-effect-induced systematic error in Raman transition-based precision measurements, such as atomic interferometer gravimeters.
NASA Technical Reports Server (NTRS)
Sun, Jielun
1993-01-01
Results are presented of a test of the physically based total column water vapor retrieval algorithm of Wentz (1992) for sensitivity to realistic vertical distributions of temperature and water vapor. The ECMWF monthly averaged temperature and humidity fields are used to simulate the spatial pattern of systematic retrieval error of total column water vapor due to this sensitivity. The estimated systematic error is within 0.1 g/sq cm over about 70 percent of the global ocean area; systematic errors greater than 0.3 g/sq cm are expected to exist only over a few well-defined regions, about 3 percent of the global oceans, assuming that the global mean value is unbiased.
Casas, Francisco J.; Ortiz, David; Villa, Enrique; Cano, Juan L.; Cagigas, Jaime; Pérez, Ana R.; Aja, Beatriz; Terán, J. Vicente; de la Fuente, Luisa; Artal, Eduardo; Hoyland, Roger; Génova-Santos, Ricardo
2015-01-01
This paper presents preliminary polarization measurements and systematic-error characterization of the Thirty Gigahertz Instrument receiver developed for the QUIJOTE experiment. The instrument has been designed to measure the polarization of Cosmic Microwave Background radiation from the sky, obtaining the Q, U, and I Stokes parameters of the incoming signal simultaneously. Two kinds of linearly polarized input signals have been used as excitations in the polarimeter measurement tests in the laboratory; these show consistent results in terms of the Stokes parameters obtained. A measurement-based systematic-error characterization technique has been used in order to determine the possible sources of instrumental errors and to assist in the polarimeter calibration process. PMID:26251906
A study for systematic errors of the GLA forecast model in tropical regions
NASA Technical Reports Server (NTRS)
Chen, Tsing-Chang; Baker, Wayman E.; Pfaendtner, James; Corrigan, Martin
1988-01-01
From the sensitivity studies performed with the Goddard Laboratory for Atmospheres (GLA) analysis/forecast system, it was revealed that the forecast errors in the tropics affect the ability to forecast midlatitude weather in some cases. Apparently, the forecast errors occurring in the tropics can propagate to midlatitudes. Therefore, the systematic error analysis of the GLA forecast system becomes a necessary step in improving the model's forecast performance. The major effort of this study is to examine the possible impact of the hydrological-cycle forecast error on dynamical fields in the GLA forecast system.
Yang, Xiao-Xing; Critchley, Lester A; Joynt, Gavin M
2011-01-01
Thermodilution cardiac output using a pulmonary artery catheter is the reference method against which all new methods of cardiac output measurement are judged. However, thermodilution lacks precision and has a quoted precision error of ± 20%. There is uncertainty about its true precision and this causes difficulty when validating new cardiac output technology. Our aim in this investigation was to determine the current precision error of thermodilution measurements. A test rig through which water circulated at different constant rates with ports to insert catheters into a flow chamber was assembled. Flow rate was measured by an externally placed transonic flowprobe and meter. The meter was calibrated by timed filling of a cylinder. Arrow and Edwards 7Fr thermodilution catheters, connected to a Siemens SC9000 cardiac output monitor, were tested. Thermodilution readings were made by injecting 5 mL of ice-cold water. Precision error was divided into random and systematic components, which were determined separately. Between-readings (random) variability was determined for each catheter by taking sets of 10 readings at different flow rates. Coefficient of variation (CV) was calculated for each set and averaged. Between-catheter systems (systematic) variability was derived by plotting calibration lines for sets of catheters. Slopes were used to estimate the systematic component. Performances of 3 cardiac output monitors were compared: Siemens SC9000, Siemens Sirecust 1261, and Philips MP50. Five Arrow and 5 Edwards catheters were tested using the Siemens SC9000 monitor. Flow rates between 0.7 and 7.0 L/min were studied. The CV (random error) for Arrow was 5.4% and for Edwards was 4.8%. The random precision error was ± 10.0% (95% confidence limits). CV (systematic error) was 5.8% and 6.0%, respectively. The systematic precision error was ± 11.6%. The total precision error of a single thermodilution reading was ± 15.3% and ± 13.0% for triplicate readings. Precision error increased by 45% when using the Sirecust monitor and 100% when using the Philips monitor. In vitro testing of pulmonary artery catheters enabled us to measure both the random and systematic error components of thermodilution cardiac output measurement, and thus calculate the precision error. Using the Siemens monitor, we established a precision error of ± 15.3% for single and ± 13.0% for triplicate reading, which was similar to the previous estimate of ± 20%. However, this precision error was significantly worsened by using the Sirecust and Philips monitors. Clinicians should recognize that the precision error of thermodilution cardiac output is dependent on the selection of catheter and monitor model.
Measurement error is often neglected in medical literature: a systematic review.
Brakenhoff, Timo B; Mitroiu, Marian; Keogh, Ruth H; Moons, Karel G M; Groenwold, Rolf H H; van Smeden, Maarten
2018-06-01
In medical research, covariates (e.g., exposure and confounder variables) are often measured with error. While it is well accepted that this introduces bias and imprecision in exposure-outcome relations, it is unclear to what extent such issues are currently considered in research practice. The objective was to study common practices regarding covariate measurement error via a systematic review of general medicine and epidemiology literature. Original research published in 2016 in 12 high impact journals was full-text searched for phrases relating to measurement error. Reporting of measurement error and methods to investigate or correct for it were quantified and characterized. Two hundred and forty-seven (44%) of the 565 original research publications reported on the presence of measurement error. 83% of these 247 did so with respect to the exposure and/or confounder variables. Only 18 publications (7% of 247) used methods to investigate or correct for measurement error. Consequently, it is difficult for readers to judge the robustness of presented results to the existence of measurement error in the majority of publications in high impact journals. Our systematic review highlights the need for increased awareness about the possible impact of covariate measurement error. Additionally, guidance on the use of measurement error correction methods is necessary. Copyright © 2018 Elsevier Inc. All rights reserved.
ERIC Educational Resources Information Center
Walker, Grant M.; Schwartz, Myrna F.; Kimberg, Daniel Y.; Faseyitan, Olufunsho; Brecher, Adelyn; Dell, Gary S.; Coslett, H. Branch
2011-01-01
Semantic errors in aphasia (e.g., naming a horse as "dog") frequently arise from faulty mapping of concepts onto lexical items. A recent study by our group used voxel-based lesion-symptom mapping (VLSM) methods with 64 patients with chronic aphasia to identify voxels that carry an association with semantic errors. The strongest associations were…
z'-BAND GROUND-BASED DETECTION OF THE SECONDARY ECLIPSE OF WASP-19b
DOE Office of Scientific and Technical Information (OSTI.GOV)
Burton, J. R.; Watson, C. A.; Pollacco, D.
2012-08-01
We present the ground-based detection of the secondary eclipse of the transiting exoplanet WASP-19b. The observations were made in the Sloan z' band using the ULTRACAM triple-beam CCD camera mounted on the New Technology Telescope. The measurement shows a 0.088% {+-} 0.019% eclipse depth, matching previous predictions based on H- and K-band measurements. We discuss in detail our approach to the removal of errors arising due to systematics in the data set, in addition to fitting a model transit to our data. This fit returns an eclipse center, T{sub 0}, of 2455578.7676 HJD, consistent with a circular orbit. Our measurementmore » of the secondary eclipse depth is also compared to model atmospheres of WASP-19b and is found to be consistent with previous measurements at longer wavelengths for the model atmospheres we investigated.« less
Lost Muon Study for the Muon G-2 Experiment at Fermilab*
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ganguly, S.; Crnkovic, J.; Morse, W. M.
The Fermilab Muon g-2 Experiment has a goal of measuring the muon anomalous magnetic moment to a precision of 140 ppb - a fourfold improvement over the 540 ppb precision obtained by the BNL Muon g-2 Experiment. Some muons in the storage ring will interact with material and undergo bremsstrahlung, emitting radiation and loosing energy. These so called lost muons will curl in towards the center of the ring and be lost, but some of them will be detected by the calorimeters. A systematic error will arise if the lost muons have a different average spin phase than the storedmore » muons. Algorithms are being developed to estimate the relative number of lost muons, so as to optimize the stored muon beam. This study presents initial testing of algorithms that can be used to estimate the lost muons by using either double or triple detection coincidences in the calorimeters.« less
NASA Astrophysics Data System (ADS)
Liu, Zhixiang; Xing, Tingwen; Jiang, Yadong; Lv, Baobin
2018-02-01
A two-dimensional (2-D) shearing interferometer based on an amplitude chessboard grating was designed to measure the wavefront aberration of a high numerical-aperture (NA) objective. Chessboard gratings offer better diffraction efficiencies and fewer disturbing diffraction orders than traditional cross gratings. The wavefront aberration of the tested objective was retrieved from the shearing interferogram using the Fourier transform and differential Zernike polynomial-fitting methods. Grating manufacturing errors, including the duty-cycle and pattern-deviation errors, were analyzed with the Fourier transform method. Then, according to the relation between the spherical pupil and planar detector coordinates, the influence of the distortion of the pupil coordinates was simulated. Finally, the systematic error attributable to grating alignment errors was deduced through the geometrical ray-tracing method. Experimental results indicate that the measuring repeatability (3σ) of the wavefront aberration of an objective with NA 0.4 was 3.4 mλ. The systematic-error results were consistent with previous analyses. Thus, the correct wavefront aberration can be obtained after calibration.
NASA Astrophysics Data System (ADS)
Johnson, Traci L.; Sharon, Keren
2016-11-01
Until now, systematic errors in strong gravitational lens modeling have been acknowledged but have never been fully quantified. Here, we launch an investigation into the systematics induced by constraint selection. We model the simulated cluster Ares 362 times using random selections of image systems with and without spectroscopic redshifts and quantify the systematics using several diagnostics: image predictability, accuracy of model-predicted redshifts, enclosed mass, and magnification. We find that for models with >15 image systems, the image plane rms does not decrease significantly when more systems are added; however, the rms values quoted in the literature may be misleading as to the ability of a model to predict new multiple images. The mass is well constrained near the Einstein radius in all cases, and systematic error drops to <2% for models using >10 image systems. Magnification errors are smallest along the straight portions of the critical curve, and the value of the magnification is systematically lower near curved portions. For >15 systems, the systematic error on magnification is ∼2%. We report no trend in magnification error with the fraction of spectroscopic image systems when selecting constraints at random; however, when using the same selection of constraints, increasing this fraction up to ∼0.5 will increase model accuracy. The results suggest that the selection of constraints, rather than quantity alone, determines the accuracy of the magnification. We note that spectroscopic follow-up of at least a few image systems is crucial because models without any spectroscopic redshifts are inaccurate across all of our diagnostics.
Rationality in collective decision-making by ant colonies
Edwards, Susan C.; Pratt, Stephen C.
2009-01-01
Economic models of animal behaviour assume that decision-makers are rational, meaning that they assess options according to intrinsic fitness value and not by comparison with available alternatives. This expectation is frequently violated, but the significance of irrational behaviour remains controversial. One possibility is that irrationality arises from cognitive constraints that necessitate short cuts like comparative evaluation. If so, the study of whether and when irrationality occurs can illuminate cognitive mechanisms. We applied this logic in a novel setting: the collective decisions of insect societies. We tested for irrationality in colonies of Temnothorax ants choosing between two nest sites that varied in multiple attributes, such that neither site was clearly superior. In similar situations, individual animals show irrational changes in preference when a third relatively unattractive option is introduced. In contrast, we found no such effect in colonies. We suggest that immunity to irrationality in this case may result from the ants’ decentralized decision mechanism. A colony's choice does not depend on site comparison by individuals, but instead self-organizes from the interactions of multiple ants, most of which are aware of only a single site. This strategy may filter out comparative effects, preventing systematic errors that would otherwise arise from the cognitive limitations of individuals. PMID:19625319
DOE Office of Scientific and Technical Information (OSTI.GOV)
Liu Ke; Li Yanqiu; Wang Hai
Characterization of measurement accuracy of the phase-shifting point diffraction interferometer (PS/PDI) is usually performed by two-pinhole null test. In this procedure, the geometrical coma and detector tilt astigmatism systematic errors are almost one or two magnitude higher than the desired accuracy of PS/PDI. These errors must be accurately removed from the null test result to achieve high accuracy. Published calibration methods, which can remove the geometrical coma error successfully, have some limitations in calibrating the astigmatism error. In this paper, we propose a method to simultaneously calibrate the geometrical coma and detector tilt astigmatism errors in PS/PDI null test. Basedmore » on the measurement results obtained from two pinhole pairs in orthogonal directions, the method utilizes the orthogonal and rotational symmetry properties of Zernike polynomials over unit circle to calculate the systematic errors introduced in null test of PS/PDI. The experiment using PS/PDI operated at visible light is performed to verify the method. The results show that the method is effective in isolating the systematic errors of PS/PDI and the measurement accuracy of the calibrated PS/PDI is 0.0088{lambda} rms ({lambda}= 632.8 nm).« less
Correcting systematic errors in high-sensitivity deuteron polarization measurements
NASA Astrophysics Data System (ADS)
Brantjes, N. P. M.; Dzordzhadze, V.; Gebel, R.; Gonnella, F.; Gray, F. E.; van der Hoek, D. J.; Imig, A.; Kruithof, W. L.; Lazarus, D. M.; Lehrach, A.; Lorentz, B.; Messi, R.; Moricciani, D.; Morse, W. M.; Noid, G. A.; Onderwater, C. J. G.; Özben, C. S.; Prasuhn, D.; Levi Sandri, P.; Semertzidis, Y. K.; da Silva e Silva, M.; Stephenson, E. J.; Stockhorst, H.; Venanzoni, G.; Versolato, O. O.
2012-02-01
This paper reports deuteron vector and tensor beam polarization measurements taken to investigate the systematic variations due to geometric beam misalignments and high data rates. The experiments used the In-Beam Polarimeter at the KVI-Groningen and the EDDA detector at the Cooler Synchrotron COSY at Jülich. By measuring with very high statistical precision, the contributions that are second-order in the systematic errors become apparent. By calibrating the sensitivity of the polarimeter to such errors, it becomes possible to obtain information from the raw count rate values on the size of the errors and to use this information to correct the polarization measurements. During the experiment, it was possible to demonstrate that corrections were satisfactory at the level of 10 -5 for deliberately large errors. This may facilitate the real time observation of vector polarization changes smaller than 10 -6 in a search for an electric dipole moment using a storage ring.
Norman, Geoffrey R; Monteiro, Sandra D; Sherbino, Jonathan; Ilgen, Jonathan S; Schmidt, Henk G; Mamede, Silvia
2017-01-01
Contemporary theories of clinical reasoning espouse a dual processing model, which consists of a rapid, intuitive component (Type 1) and a slower, logical and analytical component (Type 2). Although the general consensus is that this dual processing model is a valid representation of clinical reasoning, the causes of diagnostic errors remain unclear. Cognitive theories about human memory propose that such errors may arise from both Type 1 and Type 2 reasoning. Errors in Type 1 reasoning may be a consequence of the associative nature of memory, which can lead to cognitive biases. However, the literature indicates that, with increasing expertise (and knowledge), the likelihood of errors decreases. Errors in Type 2 reasoning may result from the limited capacity of working memory, which constrains computational processes. In this article, the authors review the medical literature to answer two substantial questions that arise from this work: (1) To what extent do diagnostic errors originate in Type 1 (intuitive) processes versus in Type 2 (analytical) processes? (2) To what extent are errors a consequence of cognitive biases versus a consequence of knowledge deficits?The literature suggests that both Type 1 and Type 2 processes contribute to errors. Although it is possible to experimentally induce cognitive biases, particularly availability bias, the extent to which these biases actually contribute to diagnostic errors is not well established. Educational strategies directed at the recognition of biases are ineffective in reducing errors; conversely, strategies focused on the reorganization of knowledge to reduce errors have small but consistent benefits.
ERIC Educational Resources Information Center
Py, Bernard
A progress report is presented of a study which applies a system of generative grammar to error analysis. The objective of the study was to reconstruct the grammar of students' interlanguage, using a systematic analysis of errors. (Interlanguage refers to the linguistic competence of a student who possesses a relatively systematic body of rules,…
NASA Astrophysics Data System (ADS)
Adelberger, E. G.; Stubbs, C. W.; Heckel, B. R.; Su, Y.; Swanson, H. E.; Smith, G.; Gundlach, J. H.; Rogers, W. F.
1990-11-01
A sensitive, systematic search for feeble, macroscopic forces arising from the exchange of hypothetical ultra-low-mass bosons was made by observing the differential acceleration of two different test body pairs toward two different sources. Our differential accelerometer-a highly symmetric, continuously rotating torsion balance-incorporated several innovations that effectively suppressed systematic errors. All known sources of systematic error were demonstrated to be negligible in comparison to our fluctuating errors which are roughly 7 times larger than the fundamental limit set by the fact that we observe an oscillator at room temperature with a given damping time. Our 1σ limits on the horizontal differential acceleration of Be/Al or Be/Cu test body pairs in the field of the Earth, Δa⊥=(2.1+/-2.1)×10-11 cm s-2 and Δa⊥=(0.8+/-1.7)×10-11 cm s-2, respectively, set improved bounds on Yukawa interactions mediated by bosons with masses ranging between mbc2~=3×10-18 and mbc2~=1×10-6 eV. For example, our constraints on infinite-range vector interactions with charges of B and of B-L are roughly 10 and 2 times more sensitive than those obtained by Roll, Krotkov, and Dicke using the field of the Sun. Furthermore we set stringent constraints down to λ=1 m, while those of solar experiments are weak for λ<1 AU. In terms of the weak equivalence principle in the field of the Earth, our 1σ result corresponds to mi/mg(Cu)-mi/mg(Be)=(0.2+/-1.0)×10-11. Our results also yield stringent constraints on the nonsymmetric gravitation theory of Moffat and on the anomalous acceleration of antimatter in proposed ``quantum gravity'' models, and have implications for lunar-ranging tests of the strong equivalence principle. Our 1σ limit on the differential acceleration of Be/Al test body pairs toward a 1.5 Mg Pb laboratory source, Δa=(-0.15+/-1.31)×10-10 cm s-2, provides constraints on Yukawa interactions with ranges down to 10 cm, and on interactions whose charge is B-2L.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Parker, S
2015-06-15
Purpose: To evaluate the ability of statistical process control methods to detect systematic errors when using a two dimensional (2D) detector array for routine electron beam energy verification. Methods: Electron beam energy constancy was measured using an aluminum wedge and a 2D diode array on four linear accelerators. Process control limits were established. Measurements were recorded in control charts and compared with both calculated process control limits and TG-142 recommended specification limits. The data was tested for normality, process capability and process acceptability. Additional measurements were recorded while systematic errors were intentionally introduced. Systematic errors included shifts in the alignmentmore » of the wedge, incorrect orientation of the wedge, and incorrect array calibration. Results: Control limits calculated for each beam were smaller than the recommended specification limits. Process capability and process acceptability ratios were greater than one in all cases. All data was normally distributed. Shifts in the alignment of the wedge were most apparent for low energies. The smallest shift (0.5 mm) was detectable using process control limits in some cases, while the largest shift (2 mm) was detectable using specification limits in only one case. The wedge orientation tested did not affect the measurements as this did not affect the thickness of aluminum over the detectors of interest. Array calibration dependence varied with energy and selected array calibration. 6 MeV was the least sensitive to array calibration selection while 16 MeV was the most sensitive. Conclusion: Statistical process control methods demonstrated that the data distribution was normally distributed, the process was capable of meeting specifications, and that the process was centered within the specification limits. Though not all systematic errors were distinguishable from random errors, process control limits increased the ability to detect systematic errors using routine measurement of electron beam energy constancy.« less
Michael Köhl; Charles Scott; Daniel Plugge
2013-01-01
Uncertainties are a composite of errors arising from observations and the appropriateness of models. An error budget approach can be used to identify and accumulate the sources of errors to estimate change in emissions between two points in time. Various forest monitoring approaches can be used to estimate the changes in emissions due to deforestation and forest...
Thirty Years of Improving the NCEP Global Forecast System
NASA Astrophysics Data System (ADS)
White, G. H.; Manikin, G.; Yang, F.
2014-12-01
Current eight day forecasts by the NCEP Global Forecast System are as accurate as five day forecasts 30 years ago. This revolution in weather forecasting reflects increases in computer power, improvements in the assimilation of observations, especially satellite data, improvements in model physics, improvements in observations and international cooperation and competition. One important component has been and is the diagnosis, evaluation and reduction of systematic errors. The effect of proposed improvements in the GFS on systematic errors is one component of the thorough testing of such improvements by the Global Climate and Weather Modeling Branch. Examples of reductions in systematic errors in zonal mean temperatures and winds and other fields will be presented. One challenge in evaluating systematic errors is uncertainty in what reality is. Model initial states can be regarded as the best overall depiction of the atmosphere, but can be misleading in areas of few observations or for fields not well observed such as humidity or precipitation over the oceans. Verification of model physics is particularly difficult. The Environmental Modeling Center emphasizes the evaluation of systematic biases against observations. Recently EMC has placed greater emphasis on synoptic evaluation and on precipitation, 2-meter temperatures and dew points and 10 meter winds. A weekly EMC map discussion reviews the performance of many models over the United States and has helped diagnose and alleviate significant systematic errors in the GFS, including a near surface summertime evening cold wet bias over the eastern US and a multi-week period when the GFS persistently developed bogus tropical storms off Central America. The GFS exhibits a wet bias for light rain and a dry bias for moderate to heavy rain over the continental United States. Significant changes to the GFS are scheduled to be implemented in the fall of 2014. These include higher resolution, improved physics and improvements to the assimilation. These changes significantly improve the tropospheric flow and reduce a tropical upper tropospheric warm bias. One important error remaining is the failure of the GFS to maintain deep convection over Indonesia and in the tropical west Pacific. This and other current systematic errors will be presented.
Analysis of the vibratory excitation arising from spiral bevel gears
NASA Technical Reports Server (NTRS)
Mark, William D.
1987-01-01
Tools required to understand and predict in terms of its underlying causes the vibratory excitation arising from meshing spiral bevel gears are developed. A generalized three component transmission error of meshing spiral bevel gears is defined. Equations are derived that yield the three components of the generalized transmission error in terms of deviations of tooth running surfaces from equispaced perfect spherical involute surfaces and tooth/gearbody elastic deformations arising from the three components of the generalized force transmitted by the meshing gears. A method for incorporating these equations into the equations of motion of a gear system is described. Equations are derived for the three components of the generalized force transmitted by the gears which are valid whenever inertial effects of the meshing gears and their supports are negligible. Bearing offsets from the positions occupied by the shaft centerlines of perfect spherical involute bevel gears and bearing/bearing support flexibilities enter into the computation of these forces.
Within-Tunnel Variations in Pressure Data for Three Transonic Wind Tunnels
NASA Technical Reports Server (NTRS)
DeLoach, Richard
2014-01-01
This paper compares the results of pressure measurements made on the same test article with the same test matrix in three transonic wind tunnels. A comparison is presented of the unexplained variance associated with polar replicates acquired in each tunnel. The impact of a significance component of systematic (not random) unexplained variance is reviewed, and the results of analyses of variance are presented to assess the degree of significant systematic error in these representative wind tunnel tests. Total uncertainty estimates are reported for 140 samples of pressure data, quantifying the effects of within-polar random errors and between-polar systematic bias errors.
The Origin of Systematic Errors in the GCM Simulation of ITCZ Precipitation
NASA Technical Reports Server (NTRS)
Chao, Winston C.; Suarez, M. J.; Bacmeister, J. T.; Chen, B.; Takacs, L. L.
2006-01-01
Previous GCM studies have found that the systematic errors in the GCM simulation of the seasonal mean ITCZ intensity and location could be substantially corrected by adding suitable amount of rain re-evaporation or cumulus momentum transport. However, the reason(s) for these systematic errors and solutions has remained a puzzle. In this work the knowledge gained from previous studies of the ITCZ in an aqua-planet model with zonally uniform SST is applied to solve this puzzle. The solution is supported by further aqua-planet and full model experiments using the latest version of the Goddard Earth Observing System GCM.
NASA Technical Reports Server (NTRS)
Rodriguez, G.
1981-01-01
A function space approach to smoothing is used to obtain a set of model error estimates inherent in a reduced-order model. By establishing knowledge of inevitable deficiencies in the truncated model, the error estimates provide a foundation for updating the model and thereby improving system performance. The function space smoothing solution leads to a specification of a method for computation of the model error estimates and development of model error analysis techniques for comparison between actual and estimated errors. The paper summarizes the model error estimation approach as well as an application arising in the area of modeling for spacecraft attitude control.
Model error estimation for distributed systems described by elliptic equations
NASA Technical Reports Server (NTRS)
Rodriguez, G.
1983-01-01
A function space approach is used to develop a theory for estimation of the errors inherent in an elliptic partial differential equation model for a distributed parameter system. By establishing knowledge of the inevitable deficiencies in the model, the error estimates provide a foundation for updating the model. The function space solution leads to a specification of a method for computation of the model error estimates and development of model error analysis techniques for comparison between actual and estimated errors. The paper summarizes the model error estimation approach as well as an application arising in the area of modeling for static shape determination of large flexible systems.
Awareness of technology-induced errors and processes for identifying and preventing such errors.
Bellwood, Paule; Borycki, Elizabeth M; Kushniruk, Andre W
2015-01-01
There is a need to determine if organizations working with health information technology are aware of technology-induced errors and how they are addressing and preventing them. The purpose of this study was to: a) determine the degree of technology-induced error awareness in various Canadian healthcare organizations, and b) identify those processes and procedures that are currently in place to help address, manage, and prevent technology-induced errors. We identified a lack of technology-induced error awareness among participants. Participants identified there was a lack of well-defined procedures in place for reporting technology-induced errors, addressing them when they arise, and preventing them.
Quantifying Errors in TRMM-Based Multi-Sensor QPE Products Over Land in Preparation for GPM
NASA Technical Reports Server (NTRS)
Peters-Lidard, Christa D.; Tian, Yudong
2011-01-01
Determining uncertainties in satellite-based multi-sensor quantitative precipitation estimates over land of fundamental importance to both data producers and hydro climatological applications. ,Evaluating TRMM-era products also lays the groundwork and sets the direction for algorithm and applications development for future missions including GPM. QPE uncertainties result mostly from the interplay of systematic errors and random errors. In this work, we will synthesize our recent results quantifying the error characteristics of satellite-based precipitation estimates. Both systematic errors and total uncertainties have been analyzed for six different TRMM-era precipitation products (3B42, 3B42RT, CMORPH, PERSIANN, NRL and GSMap). For systematic errors, we devised an error decomposition scheme to separate errors in precipitation estimates into three independent components, hit biases, missed precipitation and false precipitation. This decomposition scheme reveals hydroclimatologically-relevant error features and provides a better link to the error sources than conventional analysis, because in the latter these error components tend to cancel one another when aggregated or averaged in space or time. For the random errors, we calculated the measurement spread from the ensemble of these six quasi-independent products, and thus produced a global map of measurement uncertainties. The map yields a global view of the error characteristics and their regional and seasonal variations, reveals many undocumented error features over areas with no validation data available, and provides better guidance to global assimilation of satellite-based precipitation data. Insights gained from these results and how they could help with GPM will be highlighted.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Johnson, Traci L.; Sharon, Keren, E-mail: tljohn@umich.edu
Until now, systematic errors in strong gravitational lens modeling have been acknowledged but have never been fully quantified. Here, we launch an investigation into the systematics induced by constraint selection. We model the simulated cluster Ares 362 times using random selections of image systems with and without spectroscopic redshifts and quantify the systematics using several diagnostics: image predictability, accuracy of model-predicted redshifts, enclosed mass, and magnification. We find that for models with >15 image systems, the image plane rms does not decrease significantly when more systems are added; however, the rms values quoted in the literature may be misleading asmore » to the ability of a model to predict new multiple images. The mass is well constrained near the Einstein radius in all cases, and systematic error drops to <2% for models using >10 image systems. Magnification errors are smallest along the straight portions of the critical curve, and the value of the magnification is systematically lower near curved portions. For >15 systems, the systematic error on magnification is ∼2%. We report no trend in magnification error with the fraction of spectroscopic image systems when selecting constraints at random; however, when using the same selection of constraints, increasing this fraction up to ∼0.5 will increase model accuracy. The results suggest that the selection of constraints, rather than quantity alone, determines the accuracy of the magnification. We note that spectroscopic follow-up of at least a few image systems is crucial because models without any spectroscopic redshifts are inaccurate across all of our diagnostics.« less
Anatomy of the Higgs fits: A first guide to statistical treatments of the theoretical uncertainties
NASA Astrophysics Data System (ADS)
Fichet, Sylvain; Moreau, Grégory
2016-04-01
The studies of the Higgs boson couplings based on the recent and upcoming LHC data open up a new window on physics beyond the Standard Model. In this paper, we propose a statistical guide to the consistent treatment of the theoretical uncertainties entering the Higgs rate fits. Both the Bayesian and frequentist approaches are systematically analysed in a unified formalism. We present analytical expressions for the marginal likelihoods, useful to implement simultaneously the experimental and theoretical uncertainties. We review the various origins of the theoretical errors (QCD, EFT, PDF, production mode contamination…). All these individual uncertainties are thoroughly combined with the help of moment-based considerations. The theoretical correlations among Higgs detection channels appear to affect the location and size of the best-fit regions in the space of Higgs couplings. We discuss the recurrent question of the shape of the prior distributions for the individual theoretical errors and find that a nearly Gaussian prior arises from the error combinations. We also develop the bias approach, which is an alternative to marginalisation providing more conservative results. The statistical framework to apply the bias principle is introduced and two realisations of the bias are proposed. Finally, depending on the statistical treatment, the Standard Model prediction for the Higgs signal strengths is found to lie within either the 68% or 95% confidence level region obtained from the latest analyses of the 7 and 8 TeV LHC datasets.
Sokolenko, Stanislav; Aucoin, Marc G
2015-09-04
The growing ubiquity of metabolomic techniques has facilitated high frequency time-course data collection for an increasing number of applications. While the concentration trends of individual metabolites can be modeled with common curve fitting techniques, a more accurate representation of the data needs to consider effects that act on more than one metabolite in a given sample. To this end, we present a simple algorithm that uses nonparametric smoothing carried out on all observed metabolites at once to identify and correct systematic error from dilution effects. In addition, we develop a simulation of metabolite concentration time-course trends to supplement available data and explore algorithm performance. Although we focus on nuclear magnetic resonance (NMR) analysis in the context of cell culture, a number of possible extensions are discussed. Realistic metabolic data was successfully simulated using a 4-step process. Starting with a set of metabolite concentration time-courses from a metabolomic experiment, each time-course was classified as either increasing, decreasing, concave, or approximately constant. Trend shapes were simulated from generic functions corresponding to each classification. The resulting shapes were then scaled to simulated compound concentrations. Finally, the scaled trends were perturbed using a combination of random and systematic errors. To detect systematic errors, a nonparametric fit was applied to each trend and percent deviations calculated at every timepoint. Systematic errors could be identified at time-points where the median percent deviation exceeded a threshold value, determined by the choice of smoothing model and the number of observed trends. Regardless of model, increasing the number of observations over a time-course resulted in more accurate error estimates, although the improvement was not particularly large between 10 and 20 samples per trend. The presented algorithm was able to identify systematic errors as small as 2.5 % under a wide range of conditions. Both the simulation framework and error correction method represent examples of time-course analysis that can be applied to further developments in (1)H-NMR methodology and the more general application of quantitative metabolomics.
Park, S B; Kim, H; Yao, M; Ellis, R; Machtay, M; Sohn, J W
2012-06-01
To quantify the systematic error of a Deformable Image Registration (DIR) system and establish Quality Assurance (QA) procedure. To address the shortfall of landmark approach which it is only available at the significant visible feature points, we adapted a Deformation Vector Map (DVM) comparison approach. We used two CT image sets (R and T image sets) taken for the same patient at different time and generated a DVM, which includes the DIR systematic error. The DVM was calculated using fine-tuned B-Spline DIR and L-BFGS optimizer. By utilizing this DVM we generated R' image set to eliminate the systematic error in DVM,. Thus, we have truth data set, R' and T image sets, and the truth DVM. To test a DIR system, we use R' and T image sets to a DIR system. We compare the test DVM to the truth DVM. If there is no systematic error, they should be identical. We built Deformation Error Histogram (DEH) for quantitative analysis. The test registration was performed with an in-house B-Spline DIR system using a stochastic gradient descent optimizer. Our example data set was generated with a head and neck patient case. We also tested CT to CBCT deformable registration. We found skin regions which interface with the air has relatively larger errors. Also mobile joints such as shoulders had larger errors. Average error for ROIs were as follows; CTV: 0.4mm, Brain stem: 1.4mm, Shoulders: 1.6mm, and Normal tissues: 0.7mm. We succeeded to build DEH approach to quantify the DVM uncertainty. Our data sets are available for testing other systems in our web page. Utilizing DEH, users can decide how much systematic error they would accept. DEH and our data can be a tool for an AAPM task group to compose a DIR system QA guideline. This project is partially supported by the Agency for Healthcare Research and Quality (AHRQ) grant 1R18HS017424-01A2. © 2012 American Association of Physicists in Medicine.
[Relations between health information systems and patient safety].
Nøhr, Christian
2012-11-05
Health information systems have the potential to reduce medical errors, and indeed many studies have shown a significant reduction. However, if the systems are not designed and implemented properly, there is evidence that suggest that new types of errors will arise--i.e., technology-induced errors. Health information systems will need to undergo a more rigorous evaluation. Usability evaluation and simulation test with humans in the loop can help to detect and prevent technology-induced errors before they are deployed in real health-care settings.
The Effect of Systematic Error in Forced Oscillation Testing
NASA Technical Reports Server (NTRS)
Williams, Brianne Y.; Landman, Drew; Flory, Isaac L., IV; Murphy, Patrick C.
2012-01-01
One of the fundamental problems in flight dynamics is the formulation of aerodynamic forces and moments acting on an aircraft in arbitrary motion. Classically, conventional stability derivatives are used for the representation of aerodynamic loads in the aircraft equations of motion. However, for modern aircraft with highly nonlinear and unsteady aerodynamic characteristics undergoing maneuvers at high angle of attack and/or angular rates the conventional stability derivative model is no longer valid. Attempts to formulate aerodynamic model equations with unsteady terms are based on several different wind tunnel techniques: for example, captive, wind tunnel single degree-of-freedom, and wind tunnel free-flying techniques. One of the most common techniques is forced oscillation testing. However, the forced oscillation testing method does not address the systematic and systematic correlation errors from the test apparatus that cause inconsistencies in the measured oscillatory stability derivatives. The primary objective of this study is to identify the possible sources and magnitude of systematic error in representative dynamic test apparatuses. Sensitivities of the longitudinal stability derivatives to systematic errors are computed, using a high fidelity simulation of a forced oscillation test rig, and assessed using both Design of Experiments and Monte Carlo methods.
NASA Astrophysics Data System (ADS)
Glover, Paul W. J.
2016-07-01
When scientists apply Archie's first law they often include an extra parameter a, which was introduced about 10 years after the equation's first publication by Winsauer et al. (1952), and which is sometimes called the "tortuosity" or "lithology" parameter. This parameter is not, however, theoretically justified. Paradoxically, the Winsauer et al. (1952) form of Archie's law often performs better than the original, more theoretically correct version. The difference in the cementation exponent calculated from these two forms of Archie's law is important, and can lead to a misestimation of reserves by at least 20 % for typical reservoir parameter values. We have examined the apparent paradox, and conclude that while the theoretical form of the law is correct, the data that we have been analysing with Archie's law have been in error. There are at least three types of systematic error that are present in most measurements: (i) a porosity error, (ii) a pore fluid salinity error, and (iii) a temperature error. Each of these systematic errors is sufficient to ensure that a non-unity value of the parameter a is required in order to fit the electrical data well. Fortunately, the inclusion of this parameter in the fit has compensated for the presence of the systematic errors in the electrical and porosity data, leading to a value of cementation exponent that is correct. The exceptions are those cementation exponents that have been calculated for individual core plugs. We make a number of recommendations for reducing the systematic errors that contribute to the problem and suggest that the value of the parameter a may now be used as an indication of data quality.
[Errors in Peruvian medical journals references].
Huamaní, Charles; Pacheco-Romero, José
2009-01-01
References are fundamental in our studies; an adequate selection is asimportant as an adequate description. To determine the number of errors in a sample of references found in Peruvian medical journals. We reviewed 515 scientific papers references selected by systematic randomized sampling and corroborated reference information with the original document or its citation in Pubmed, LILACS or SciELO-Peru. We found errors in 47,6% (245) of the references, identifying 372 types of errors; the most frequent were errors in presentation style (120), authorship (100) and title (100), mainly due to spelling mistakes (91). References error percentage was high, varied and multiple. We suggest systematic revision of references in the editorial process as well as to extend the discussion on this theme. references, periodicals, research, bibliometrics.
Analyzing Software Requirements Errors in Safety-Critical, Embedded Systems
NASA Technical Reports Server (NTRS)
Lutz, Robyn R.
1993-01-01
This paper analyzes the root causes of safety-related software errors in safety-critical, embedded systems. The results show that software errors identified as potentially hazardous to the system tend to be produced by different error mechanisms than non- safety-related software errors. Safety-related software errors are shown to arise most commonly from (1) discrepancies between the documented requirements specifications and the requirements needed for correct functioning of the system and (2) misunderstandings of the software's interface with the rest of the system. The paper uses these results to identify methods by which requirements errors can be prevented. The goal is to reduce safety-related software errors and to enhance the safety of complex, embedded systems.
Rejman, Marek
2013-01-01
The aim of this study was to analyze the error structure in propulsive movements with regard to its influence on monofin swimming speed. The random cycles performed by six swimmers were filmed during a progressive test (900m). An objective method to estimate errors committed in the area of angular displacement of the feet and monofin segments was employed. The parameters were compared with a previously described model. Mutual dependences between the level of errors, stroke frequency, stroke length and amplitude in relation to swimming velocity were analyzed. The results showed that proper foot movements and the avoidance of errors, arising at the distal part of the fin, ensure the progression of swimming speed. The individual stroke parameters distribution which consists of optimally increasing stroke frequency to the maximal possible level that enables the stabilization of stroke length leads to the minimization of errors. Identification of key elements in the stroke structure based on the analysis of errors committed should aid in improving monofin swimming technique. Key points The monofin swimming technique was evaluated through the prism of objectively defined errors committed by the swimmers. The dependences between the level of errors, stroke rate, stroke length and amplitude in relation to swimming velocity were analyzed. Optimally increasing stroke rate to the maximal possible level that enables the stabilization of stroke length leads to the minimization of errors. Propriety foot movement and the avoidance of errors arising at the distal part of fin, provide for the progression of swimming speed. The key elements improving monofin swimming technique, based on the analysis of errors committed, were designated. PMID:24149742
Supersymmetry without prejudice at the LHC
NASA Astrophysics Data System (ADS)
Conley, John A.; Gainer, James S.; Hewett, JoAnne L.; Le, My Phuong; Rizzo, Thomas G.
2011-07-01
The discovery and exploration of Supersymmetry in a model-independent fashion will be a daunting task due to the large number of soft-breaking parameters in the MSSM. In this paper, we explore the capability of the ATLAS detector at the LHC (sqrt{s}=14 TeV, 1 fb-1) to find SUSY within the 19-dimensional pMSSM subspace of the MSSM using their standard transverse missing energy and long-lived particle searches that were essentially designed for mSUGRA. To this end, we employ a set of ˜71k previously generated model points in the 19-dimensional parameter space that satisfy all of the existing experimental and theoretical constraints. Employing ATLAS-generated SM backgrounds and following their approach in each of 11 missing energy analyses as closely as possible, we explore all of these 71k model points for a possible SUSY signal. To test our analysis procedure, we first verify that we faithfully reproduce the published ATLAS results for the signal distributions for their benchmark mSUGRA model points. We then show that, requiring all sparticle masses to lie below 1(3) TeV, almost all (two-thirds) of the pMSSM model points are discovered with a significance S>5 in at least one of these 11 analyses assuming a 50% systematic error on the SM background. If this systematic error can be reduced to only 20% then this parameter space coverage is increased. These results are indicative that the ATLAS SUSY search strategy is robust under a broad class of Supersymmetric models. We then explore in detail the properties of the kinematically accessible model points which remain unobservable by these search analyses in order to ascertain problematic cases which may arise in general SUSY searches.
ERIC Educational Resources Information Center
Westerberg, Carmen E.; Hawkins, Christopher A.; Rendon, Lauren
2018-01-01
Reality-monitoring errors occur when internally generated thoughts are remembered as external occurrences. We hypothesized that sleep-dependent memory consolidation could reduce them by strengthening connections between items and their contexts during an afternoon nap. Participants viewed words and imagined their referents. Pictures of the…
Modeling Morphogenesis with Reaction-Diffusion Equations Using Galerkin Spectral Methods
2002-05-06
reaction- diffusion equation is a difficult problem in analysis that will not be addressed here. Errors will also arise from numerically approx solutions to...the ODEs. When comparing the approximate solution to actual reaction- diffusion systems found in nature, we must also take into account errors that...
The Effect of Auditory Information on Patterns of Intrusions and Reductions
ERIC Educational Resources Information Center
Slis, Anneke; van Lieshout, Pascal
2016-01-01
Purpose: The study investigates whether auditory information affects the nature of intrusion and reduction errors in reiterated speech. These errors are hypothesized to arise as a consequence of autonomous mechanisms to stabilize movement coordination. The specific question addressed is whether this process is affected by auditory information so…
Component Analysis of Errors on PERSIANN Precipitation Estimates over Urmia Lake Basin, IRAN
NASA Astrophysics Data System (ADS)
Ghajarnia, N.; Daneshkar Arasteh, P.; Liaghat, A. M.; Araghinejad, S.
2016-12-01
In this study, PERSIANN daily dataset is evaluated from 2000 to 2011 in 69 pixels over Urmia Lake basin in northwest of Iran. Different analytical approaches and indexes are used to examine PERSIANN precision in detection and estimation of rainfall rate. The residuals are decomposed into Hit, Miss and FA estimation biases while continues decomposition of systematic and random error components are also analyzed seasonally and categorically. New interpretation of estimation accuracy named "reliability on PERSIANN estimations" is introduced while the changing manners of existing categorical/statistical measures and error components are also seasonally analyzed over different rainfall rate categories. This study yields new insights into the nature of PERSIANN errors over Urmia lake basin as a semi-arid region in the middle-east, including the followings: - The analyzed contingency table indexes indicate better detection precision during spring and fall. - A relatively constant level of error is generally observed among different categories. The range of precipitation estimates at different rainfall rate categories is nearly invariant as a sign for the existence of systematic error. - Low level of reliability is observed on PERSIANN estimations at different categories which are mostly associated with high level of FA error. However, it is observed that as the rate of precipitation increase, the ability and precision of PERSIANN in rainfall detection also increases. - The systematic and random error decomposition in this area shows that PERSIANN has more difficulty in modeling the system and pattern of rainfall rather than to have bias due to rainfall uncertainties. The level of systematic error also considerably increases in heavier rainfalls. It is also important to note that PERSIANN error characteristics at each season varies due to the condition and rainfall patterns of that season which shows the necessity of seasonally different approach for the calibration of this product. Overall, we believe that different error component's analysis performed in this study, can substantially help any further local studies for post-calibration and bias reduction of PERSIANN estimations.
Galli, C
2001-07-01
It is well established that the use of polychromatic radiation in spectrophotometric assays leads to excursions from the Beer-Lambert limit. This Note models the resulting systematic error as a function of assay spectral width, slope of molecular extinction coefficient, and analyte concentration. The theoretical calculations are compared with recent experimental results; a parameter is introduced which can be used to estimate the magnitude of the systematic error in both chromatographic and nonchromatographic spectrophotometric assays. It is important to realize that the polychromatic radiation employed in common laboratory equipment can yield assay errors up to approximately 4%, even at absorption levels generally considered 'safe' (i.e. absorption <1). Thus careful consideration of instrumental spectral width, analyte concentration, and slope of molecular extinction coefficient is required to ensure robust analytical methods.
Taylor, C; Parker, J; Stratford, J; Warren, M
2018-05-01
Although all systematic and random positional setup errors can be corrected for in entirety during on-line image-guided radiotherapy, the use of a specified action level, below which no correction occurs, is also an option. The following service evaluation aimed to investigate the use of this 3 mm action level for on-line image assessment and correction (online, systematic set-up error and weekly evaluation) for lower extremity sarcoma, and understand the impact on imaging frequency and patient positioning error within one cancer centre. All patients were immobilised using a thermoplastic shell attached to a plastic base and an individual moulded footrest. A retrospective analysis of 30 patients was performed. Patient setup and correctional data derived from cone beam CT analysis was retrieved. The timing, frequency and magnitude of corrections were evaluated. The population systematic and random error was derived. 20% of patients had no systematic corrections over the duration of treatment, and 47% had one. The maximum number of systematic corrections per course of radiotherapy was 4, which occurred for 2 patients. 34% of episodes occurred within the first 5 fractions. All patients had at least one observed translational error during their treatment greater than 0.3 cm, and 80% of patients had at least one observed translational error during their treatment greater than 0.5 cm. The population systematic error was 0.14 cm, 0.10 cm, 0.14 cm and random error was 0.27 cm, 0.22 cm, 0.23 cm in the lateral, caudocranial and anteroposterial directions. The required Planning Target Volume margin for the study population was 0.55 cm, 0.41 cm and 0.50 cm in the lateral, caudocranial and anteroposterial directions. The 3 mm action level for image assessment and correction prior to delivery reduced the imaging burden and focussed intervention on patients that exhibited greater positional variability. This strategy could be an efficient deployment of departmental resources if full daily correction of positional setup error is not possible. Copyright © 2017. Published by Elsevier Ltd.
ERIC Educational Resources Information Center
Rice, Bart F.; Wilde, Carroll O.
It is noted that with the prominence of computers in today's technological society, digital communication systems have become widely used in a variety of applications. Some of the problems that arise in digital communications systems are described. This unit presents the problem of correcting errors in such systems. Error correcting codes are…
Helical tomotherapy setup variations in canine nasal tumor patients immobilized with a bite block.
Kubicek, Lyndsay N; Seo, Songwon; Chappell, Richard J; Jeraj, Robert; Forrest, Lisa J
2012-01-01
The purpose of our study was to compare setup variation in four degrees of freedom (vertical, longitudinal, lateral, and roll) between canine nasal tumor patients immobilized with a mattress and bite block, versus a mattress alone. Our secondary aim was to define a clinical target volume (CTV) to planning target volume (PTV) expansion margin based on our mean systematic error values associated with nasal tumor patients immobilized by a mattress and bite block. We evaluated six parameters for setup corrections: systematic error, random error, patient-patient variation in systematic errors, the magnitude of patient-specific random errors (root mean square [RMS]), distance error, and the variation of setup corrections from zero shift. The variations in all parameters were statistically smaller in the group immobilized by a mattress and bite block. The mean setup corrections in the mattress and bite block group ranged from 0.91 mm to 1.59 mm for the translational errors and 0.5°. Although most veterinary radiation facilities do not have access to Image-guided radiotherapy (IGRT), we identified a need for more rigid fixation, established the value of adding IGRT to veterinary radiation therapy, and define the CTV-PTV setup error margin for canine nasal tumor patients immobilized in a mattress and bite block. © 2012 Veterinary Radiology & Ultrasound.
Closing the brain-to-brain loop in laboratory testing.
Plebani, Mario; Lippi, Giuseppe
2011-07-01
Abstract The delivery of laboratory services has been described 40 years ago and defined with the foremost concept of "brain-to-brain turnaround time loop". This concept consists of several processes, including the final step which is the action undertaken on the patient based on laboratory information. Unfortunately, the need for systematic feedback to improve the value of laboratory services has been poorly understood and, even more risky, poorly applied in daily laboratory practice. Currently, major problems arise from the unavailability of consensually accepted quality specifications for the extra-analytical phase of laboratory testing. This, in turn, does not allow clinical laboratories to calculate a budget for the "patient-related total error". The definition and use of the term "total error" refers only to the analytical phase, and should be better defined as "total analytical error" to avoid any confusion and misinterpretation. According to the hierarchical approach to classify strategies to set analytical quality specifications, the "assessment of the effect of analytical performance on specific clinical decision-making" is comprehensively at the top and therefore should be applied as much as possible to address analytical efforts towards effective goals. In addition, an increasing number of laboratories worldwide are adopting risk management strategies such as FMEA, FRACAS, LEAN and Six Sigma since these techniques allow the identification of the most critical steps in the total testing process, and to reduce the patient-related risk of error. As a matter of fact, an increasing number of laboratory professionals recognize the importance of understanding and monitoring any step in the total testing process, including the appropriateness of the test request as well as the appropriate interpretation and utilization of test results.
Absolute Timing of the Crab Pulsar with RXTE
NASA Technical Reports Server (NTRS)
Rots, Arnold H.; Jahoda, Keith; Lyne, Andrew G.
2004-01-01
We have monitored the phase of the main X-ray pulse of the Crab pulsar with the Rossi X-ray Timing Explorer (RXTE) for almost eight years, since the start of the mission in January 1996. The absolute time of RXTE's clock is sufficiently accurate to allow this phase to be compared directly with the radio profile. Our monitoring observations of the pulsar took place bi-weekly (during the periods when it was at least 30 degrees from the Sun) and we correlated the data with radio timing ephemerides derived from observations made at Jodrell Bank. We have determined the phase of the X-ray main pulse for each observation with a typical error in the individual data points of 50 microseconds. The total ensemble is consistent with a phase that is constant over the monitoring period, with the X-ray pulse leading the radio pulse by 0.01025 plus or minus 0.00120 period in phase, or 344 plus or minus 40 microseconds in time. The error estimate is dominated by a systematic error of 40 microseconds, most likely constant, arising from uncertainties in the instrumental calibration of the radio data. The statistical error is 0.00015 period, or 5 microseconds. The separation of the main pulse and interpulse appears to be unchanging at time scales of a year or less, with an average value of 0.4001 plus or minus 0.0002 period. There is no apparent variation in these values with energy over the 2-30 keV range. The lag between the radio and X-ray pulses ma be constant in phase (i.e., rotational in nature) or constant in time (i.e., due to a pathlength difference). We are not (yet) able to distinguish between these two interpretations.
Dynamically correcting two-qubit gates against any systematic logical error
NASA Astrophysics Data System (ADS)
Calderon Vargas, Fernando Antonio
The reliability of quantum information processing depends on the ability to deal with noise and error in an efficient way. A significant source of error in many settings is coherent, systematic gate error. This work introduces a set of composite pulse sequences that generate maximally entangling gates and correct all systematic errors within the logical subspace to arbitrary order. These sequences are applica- ble for any two-qubit interaction Hamiltonian, and make no assumptions about the underlying noise mechanism except that it is constant on the timescale of the opera- tion. The prime use for our results will be in cases where one has limited knowledge of the underlying physical noise and control mechanisms, highly constrained control, or both. In particular, we apply these composite pulse sequences to the quantum system formed by two capacitively coupled singlet-triplet qubits, which is charac- terized by having constrained control and noise sources that are low frequency and of a non-Markovian nature.
Hughes, Charmayne M L; Baber, Chris; Bienkiewicz, Marta; Worthington, Andrew; Hazell, Alexa; Hermsdörfer, Joachim
2015-01-01
Approximately 33% of stroke patients have difficulty performing activities of daily living, often committing errors during the planning and execution of such activities. The objective of this study was to evaluate the ability of the human error identification (HEI) technique SHERPA (Systematic Human Error Reduction and Prediction Approach) to predict errors during the performance of daily activities in stroke patients with left and right hemisphere lesions. Using SHERPA we successfully predicted 36 of the 38 observed errors, with analysis indicating that the proportion of predicted and observed errors was similar for all sub-tasks and severity levels. HEI results were used to develop compensatory cognitive strategies that clinicians could employ to reduce or prevent errors from occurring. This study provides evidence for the reliability and validity of SHERPA in the design of cognitive rehabilitation strategies in stroke populations.
Internal robustness: systematic search for systematic bias in SN Ia data
NASA Astrophysics Data System (ADS)
Amendola, Luca; Marra, Valerio; Quartin, Miguel
2013-04-01
A great deal of effort is currently being devoted to understanding, estimating and removing systematic errors in cosmological data. In the particular case of Type Ia supernovae, systematics are starting to dominate the error budget. Here we propose a Bayesian tool for carrying out a systematic search for systematic contamination. This serves as an extension to the standard goodness-of-fit tests and allows not only to cross-check raw or processed data for the presence of systematics but also to pin-point the data that are most likely contaminated. We successfully test our tool with mock catalogues and conclude that the Union2.1 data do not possess a significant amount of systematics. Finally, we show that if one includes in Union2.1 the supernovae that originally failed the quality cuts, our tool signals the presence of systematics at over 3.8σ confidence level.
Jiang, Jie; Yu, Wenbo; Zhang, Guangjun
2017-01-01
Navigation accuracy is one of the key performance indicators of an inertial navigation system (INS). Requirements for an accuracy assessment of an INS in a real work environment are exceedingly urgent because of enormous differences between real work and laboratory test environments. An attitude accuracy assessment of an INS based on the intensified high dynamic star tracker (IHDST) is particularly suitable for a real complex dynamic environment. However, the coupled systematic coordinate errors of an INS and the IHDST severely decrease the attitude assessment accuracy of an INS. Given that, a high-accuracy decoupling estimation method of the above systematic coordinate errors based on the constrained least squares (CLS) method is proposed in this paper. The reference frame of the IHDST is firstly converted to be consistent with that of the INS because their reference frames are completely different. Thereafter, the decoupling estimation model of the systematic coordinate errors is established and the CLS-based optimization method is utilized to estimate errors accurately. After compensating for error, the attitude accuracy of an INS can be assessed based on IHDST accurately. Both simulated experiments and real flight experiments of aircraft are conducted, and the experimental results demonstrate that the proposed method is effective and shows excellent performance for the attitude accuracy assessment of an INS in a real work environment. PMID:28991179
Ronchi, Roberta; Revol, Patrice; Katayama, Masahiro; Rossetti, Yves; Farnè, Alessandro
2011-01-01
During the procedure of prism adaptation, subjects execute pointing movements to visual targets under a lateral optical displacement: As consequence of the discrepancy between visual and proprioceptive inputs, their visuo-motor activity is characterized by pointing errors. The perception of such final errors triggers error-correction processes that eventually result into sensori-motor compensation, opposite to the prismatic displacement (i.e., after-effects). Here we tested whether the mere observation of erroneous pointing movements, similar to those executed during prism adaptation, is sufficient to produce adaptation-like after-effects. Neurotypical participants observed, from a first-person perspective, the examiner's arm making incorrect pointing movements that systematically overshot visual targets location to the right, thus simulating a rightward optical deviation. Three classical after-effect measures (proprioceptive, visual and visual-proprioceptive shift) were recorded before and after first-person's perspective observation of pointing errors. Results showed that mere visual exposure to an arm that systematically points on the right-side of a target (i.e., without error correction) produces a leftward after-effect, which mostly affects the observer's proprioceptive estimation of her body midline. In addition, being exposed to such a constant visual error induced in the observer the illusion “to feel” the seen movement. These findings indicate that it is possible to elicit sensori-motor after-effects by mere observation of movement errors. PMID:21731649
The consecutive dry days to trigger rainfall over West Africa
NASA Astrophysics Data System (ADS)
Lee, J. H.
2018-01-01
In order to resolve contradictions in addressing a soil moisture-precipitation feedback mechanism over West Africa and to clarify the impact of antecedent soil moisture on subsequent rainfall evolution, we first validated various data sets (SMOS satellite soil moisture observations, NOAH land surface model, TRMM rainfall, CMORPH rainfall and HadGEM climate models) with the Analyses Multidisciplinaires de la Mousson Africaine (AMMA) field campaign data. Based on this analysis, it was suggested that biases of data sets might cause contradictions in studying mechanisms. Thus, by taking into account uncertainties in data, it was found that the approach of consecutive dry days (i.e. a relative comparison of time-series) showed consistency across various data sets, while the direct comparison approach for soil moisture state and rainfall did not. Thus, it was discussed that it may be difficult to directly relate rain with soil moisture as the absolute value, however, it may be reasonable to compare a temporal progress of the variables. Based upon the results consistently showing a positive relationship between the consecutive dry days and rainfall, this study supports a negative feedback often neglected by climate model structure. This approach is less sensitive to interpretation errors arising from systematic errors in data sets, as this measures a temporal gradient of soil moisture state.
Davis, Jean -Paul; Brown, Justin L.; Knudson, Marcus D.; ...
2014-11-26
In this research, magnetically-driven, planar shockless-compression experiments to multi-megabar pressures were performed on tantalum samples using a stripline target geometry. Free-surface velocity waveforms were measured in 15 cases; nine of these in a dual-sample configuration with two samples of different thicknesses on opposing electrodes, and six in a single-sample configuration with a bare electrode opposite the sample. Details are given on the application of inverse Lagrangian analysis (ILA) to these data, including potential sources of error. The most significant source of systematic error, particularly for single-sample experiments, was found to arise from the pulse-shape dependent free-surface reflected wave interactions withmore » the deviatoric-stress response of tantalum. This could cause local, possibly temporary, unloading of material from a ramp compressed state, and thus multi-value response in wave speed that invalidates the free-surface to in-material velocity mapping step of ILA. By averaging all 15 data sets, a final result for the principal quasi-isentrope of tantalum in stress-strain was obtained to a peak longitudinal stress of 330 GPa with conservative uncertainty bounds of ±4.5% in stress. The result agrees well with a tabular equation of state developed at Los Alamos National Laboratory.« less
Han, J W; Van Leeuwen, G M; Mizushina, S; Van de Kamer, J B; Maruyama, K; Sugiura, T; Azzopardi, D V; Edwards, A D
2001-07-01
In this study we present a design for a multi-frequency microwave radiometer aimed at prolonged monitoring of deep brain temperature in newborn infants and suitable for use during hypothermic neural rescue therapy. We identify appropriate hardware to measure brightness temperature and evaluate the accuracy of the measurements. We describe a method to estimate the tissue temperature distribution from measured brightness temperatures which uses the results of numerical simulations of the tissue temperature as well as the propagation of the microwaves in a realistic detailed three-dimensional infant head model. The temperature retrieval method is then used to evaluate how the statistical fluctuations in the measured brightness temperatures limit the confidence interval for the estimated temperature: for an 18 degrees C temperature differential between cooled surface and deep brain we found a standard error in the estimated central brain temperature of 0.75 degrees C. Evaluation of the systematic errors arising from inaccuracies in model parameters showed that realistic deviations in tissue parameters have little impact compared to uncertainty in the thickness of the bolus between the receiving antenna and the infant's head or in the skull thickness. This highlights the need to pay particular attention to these latter parameters in future practical implementation of the technique.
Interferometric Techniques for Gravitational Wave Detection in Space
NASA Technical Reports Server (NTRS)
Stebbins, Robin T; Bender, Peter L.
2000-01-01
The Laser Interferometer Space Antenna (LISA) mission will detect gravitational waves from galactic and extragalactic sources, most importantly those involving supermassive black holes. The primary goal of this project is to investigate stability and robustness issues associated with LISA interferometry. We specifically propose to study systematic errors arising from: optical misalignments, optical surface errors, thermal effects and pointing tolerances. This report covers the first fiscal year of the grant, from January 1st to December 31st 1999. We have employed an optical modeling tool to evaluate the effect of misplaced and misaligned optical components. Preliminary results seem to indicate that positional tolerances of one micron and angular tolerances of 0.6 millirad produce no significant effect on the achievable contrast of the interference pattern. This report also outlines research plans for the second fiscal year of the grant, from January 1st to December 31st 2000. Since the work under NAG5-6880 has gone more rapidly than projected, our test bed interferometer is operational, and can be used for measurements of effects that cause beam motion. Hence, we will design, build and characterize a sensor for measuring beam motion, and then install it. We are also planning a differential wavefront sensor based on a quadrant photodiode as a first generation sensor.
Bartz, Daniel; Hatrick, Kerr; Hesse, Christian W; Müller, Klaus-Robert; Lemm, Steven
2013-01-01
Robust and reliable covariance estimates play a decisive role in financial and many other applications. An important class of estimators is based on factor models. Here, we show by extensive Monte Carlo simulations that covariance matrices derived from the statistical Factor Analysis model exhibit a systematic error, which is similar to the well-known systematic error of the spectrum of the sample covariance matrix. Moreover, we introduce the Directional Variance Adjustment (DVA) algorithm, which diminishes the systematic error. In a thorough empirical study for the US, European, and Hong Kong stock market we show that our proposed method leads to improved portfolio allocation.
Bartz, Daniel; Hatrick, Kerr; Hesse, Christian W.; Müller, Klaus-Robert; Lemm, Steven
2013-01-01
Robust and reliable covariance estimates play a decisive role in financial and many other applications. An important class of estimators is based on factor models. Here, we show by extensive Monte Carlo simulations that covariance matrices derived from the statistical Factor Analysis model exhibit a systematic error, which is similar to the well-known systematic error of the spectrum of the sample covariance matrix. Moreover, we introduce the Directional Variance Adjustment (DVA) algorithm, which diminishes the systematic error. In a thorough empirical study for the US, European, and Hong Kong stock market we show that our proposed method leads to improved portfolio allocation. PMID:23844016
Target Uncertainty Mediates Sensorimotor Error Correction
Vijayakumar, Sethu; Wolpert, Daniel M.
2017-01-01
Human movements are prone to errors that arise from inaccuracies in both our perceptual processing and execution of motor commands. We can reduce such errors by both improving our estimates of the state of the world and through online error correction of the ongoing action. Two prominent frameworks that explain how humans solve these problems are Bayesian estimation and stochastic optimal feedback control. Here we examine the interaction between estimation and control by asking if uncertainty in estimates affects how subjects correct for errors that may arise during the movement. Unbeknownst to participants, we randomly shifted the visual feedback of their finger position as they reached to indicate the center of mass of an object. Even though participants were given ample time to compensate for this perturbation, they only fully corrected for the induced error on trials with low uncertainty about center of mass, with correction only partial in trials involving more uncertainty. The analysis of subjects’ scores revealed that participants corrected for errors just enough to avoid significant decrease in their overall scores, in agreement with the minimal intervention principle of optimal feedback control. We explain this behavior with a term in the loss function that accounts for the additional effort of adjusting one’s response. By suggesting that subjects’ decision uncertainty, as reflected in their posterior distribution, is a major factor in determining how their sensorimotor system responds to error, our findings support theoretical models in which the decision making and control processes are fully integrated. PMID:28129323
Target Uncertainty Mediates Sensorimotor Error Correction.
Acerbi, Luigi; Vijayakumar, Sethu; Wolpert, Daniel M
2017-01-01
Human movements are prone to errors that arise from inaccuracies in both our perceptual processing and execution of motor commands. We can reduce such errors by both improving our estimates of the state of the world and through online error correction of the ongoing action. Two prominent frameworks that explain how humans solve these problems are Bayesian estimation and stochastic optimal feedback control. Here we examine the interaction between estimation and control by asking if uncertainty in estimates affects how subjects correct for errors that may arise during the movement. Unbeknownst to participants, we randomly shifted the visual feedback of their finger position as they reached to indicate the center of mass of an object. Even though participants were given ample time to compensate for this perturbation, they only fully corrected for the induced error on trials with low uncertainty about center of mass, with correction only partial in trials involving more uncertainty. The analysis of subjects' scores revealed that participants corrected for errors just enough to avoid significant decrease in their overall scores, in agreement with the minimal intervention principle of optimal feedback control. We explain this behavior with a term in the loss function that accounts for the additional effort of adjusting one's response. By suggesting that subjects' decision uncertainty, as reflected in their posterior distribution, is a major factor in determining how their sensorimotor system responds to error, our findings support theoretical models in which the decision making and control processes are fully integrated.
NASA Technical Reports Server (NTRS)
Briggs, Hugh C.
2008-01-01
An error budget is a commonly used tool in design of complex aerospace systems. It represents system performance requirements in terms of allowable errors and flows these down through a hierarchical structure to lower assemblies and components. The requirements may simply be 'allocated' based upon heuristics or experience, or they may be designed through use of physics-based models. This paper presents a basis for developing an error budget for models of the system, as opposed to the system itself. The need for model error budgets arises when system models are a principle design agent as is increasingly more common for poorly testable high performance space systems.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Carson, M; Molineu, A; Taylor, P
Purpose: To analyze the most recent results of IROC Houston’s anthropomorphic H&N phantom to determine the nature of failing irradiations and the feasibility of altering pass/fail credentialing criteria. Methods: IROC Houston’s H&N phantom, used for IMRT credentialing for NCI-sponsored clinical trials, requires that an institution’s treatment plan must agree with measurement within 7% (TLD doses) and ≥85% pixels must pass 7%/4 mm gamma analysis. 156 phantom irradiations (November 2014 – October 2015) were re-evaluated using tighter criteria: 1) 5% TLD and 5%/4 mm, 2) 5% TLD and 5%/3 mm, 3) 4% TLD and 4%/4 mm, and 4) 3% TLD andmore » 3%/3 mm. Failure/poor performance rates were evaluated with respect to individual film and TLD performance by location in the phantom. Overall poor phantom results were characterized qualitatively as systematic (dosimetric) errors, setup errors/positional shifts, global but non-systematic errors, and errors affecting only a local region. Results: The pass rate for these phantoms using current criteria is 90%. Substituting criteria 1-4 reduces the overall pass rate to 77%, 70%, 63%, and 37%, respectively. Statistical analyses indicated the probability of noise-induced TLD failure at the 5% criterion was <0.5%. Using criteria 1, TLD results were most often the cause of failure (86% failed TLD while 61% failed film), with most failures identified in the primary PTV (77% cases). Other criteria posed similar results. Irradiations that failed from film only were overwhelmingly associated with phantom shifts/setup errors (≥80% cases). Results failing criteria 1 were primarily diagnosed as systematic: 58% of cases. 11% were setup/positioning errors, 8% were global non-systematic errors, and 22% were local errors. Conclusion: This study demonstrates that 5% TLD and 5%/4 mm gamma criteria may be both practically and theoretically achievable. Further work is necessary to diagnose and resolve dosimetric inaccuracy in these trials, particularly for systematic dose errors. This work is funded by NCI Grant CA180803.« less
Description of a Quality Assurance Process for a Surface Wind Database in Eastern Canada
NASA Astrophysics Data System (ADS)
Lucio-Eceiza, E. E.; Gonzalez-Rouco, F. J.; Navarro, J.; Beltrami, H.; García-Bustamante, E.; Hidalgo; Jiménez, P. A.
2011-12-01
Meteorological data of good quality are important for understanding both global and regional climates. The data are subject to different types of measurement errors that can be roughly classified into three groups: random, systematic and rough errors. Random errors are unavoidable and inherent to the very nature of the measurements as instrumental responses to real physical phenomena, as they are an approximate representation of the reality. Systematic errors are produced by instrumental scale shifts and drifts or by some more or less persistent factors that are not taken into account (changes in the sensor, recalibrations or location displacements). Rough errors are associated with sensor malfunction or mismanagement arising during data processing, transmission, reception or storage. It is essential to develop procedures that allow to identify, and correct if possible, the errors in observed series, in order to improve the quality of the data sets and reach solid conclusions in the studies. This work summarizes the evaluation made to date of the quality assurance process of wind speed and direction data acquired over a wide area in Eastern Canada (including the provinces of Quebec, Prince Edward Island, New Brunswick, Nova Scotia, and Newfoundland and Labrador), a region of the adjacent maritime areas and a region of the north-eastern U.S. (Maine, New Hampshire, Massachusetts, New York and Vermont). The data set consists of 527 stations, it spans the period 1940-2009 and has been compiled from three different sources: a set of 344 land sites obtained from Environment Canada (1940-2009), a subset of 40 buoys distributed over the East Coast and the Canadian Great Lakes (1988-2008) provided by Fisheries and Oceans, and a subset of 143 land sites combining both eastern Canada and north-eastern U.S. provided by the National Center of Atmospheric Research (1975-2007). The data have been compiled and subsequently a set of quality assurance techniques have been applied to explore the detection and later treatment of errors within measurements. These techniques involve, among others, detection of manipulation errors, limit checks to avoid unrealistic records and temporal consistency checks to suppress abnormally low/high variations. There are other issues specifically related to the heterogeneous nature of this data set such as unit-conversion and changes in recording times or direction resolution over time. Ensuring the quality of wind observations is essential for the later analysis that will focus in exploring the wind field behaviour at the regional scale, with a special interest over the area of Nova Scotia. The wind behaviour will be examined attending to the specific features of the regional topography and to the influence of changes in the large scale atmospheric circulation. Subsequent steps will involve a simulation of the wind field with high spatial resolution using a mesoscale model (such as WRF) and its validation with the observational data set presented herein.
Results from a NIST-EPA Interagency Agreement on Understanding Systematic Measurement Error in Thermal-Optical Analysis for PM Black Carbon Using Response Surfaces and Surface Confidence Intervals will be presented at the American Association for Aerosol Research (AAAR) 24th Annu...
Richards, Emilie J; Brown, Jeremy M; Barley, Anthony J; Chong, Rebecca A; Thomson, Robert C
2018-02-19
The use of large genomic datasets in phylogenetics has highlighted extensive topological variation across genes. Much of this discordance is assumed to result from biological processes. However, variation among gene trees can also be a consequence of systematic error driven by poor model fit, and the relative importance of biological versus methodological factors in explaining gene tree variation is a major unresolved question. Using mitochondrial genomes to control for biological causes of gene tree variation, we estimate the extent of gene tree discordance driven by systematic error and employ posterior prediction to highlight the role of model fit in producing this discordance. We find that the amount of discordance among mitochondrial gene trees is similar to the amount of discordance found in other studies that assume only biological causes of variation. This similarity suggests that the role of systematic error in generating gene tree variation is underappreciated and critical evaluation of fit between assumed models and the data used for inference is important for the resolution of unresolved phylogenetic questions.
The accuracy of the measurements in Ulugh Beg's star catalogue
NASA Astrophysics Data System (ADS)
Krisciunas, K.
1992-12-01
The star catalogue compiled by Ulugh Beg and his collaborators in Samarkand (ca. 1437) is the only catalogue primarily based on original observations between the times of Ptolemy and Tycho Brahe. Evans (1987) has given convincing evidence that Ulugh Beg's star catalogue was based on measurements made with a zodiacal armillary sphere graduated to 15(') , with interpolation to 0.2 units. He and Shevchenko (1990) were primarily interested in the systematic errors in ecliptic longitude. Shevchenko's analysis of the random errors was limited to the twelve zodiacal constellations. We have analyzed all 843 ecliptic longitudes and latitudes attributed to Ulugh Beg by Knobel (1917). This required multiplying all the longitude errors by the respective values of the cosine of the celestial latitudes. We find a random error of +/- 17minp 7 for ecliptic longitude and +/- 16minp 5 for ecliptic latitude. On the whole, the random errors are largest near the ecliptic, decreasing towards the ecliptic poles. For all of Ulugh Beg's measurements (excluding outliers) the mean systematic error is -10minp 8 +/- 0minp 8 for ecliptic longitude and 7minp 5 +/- 0minp 7 for ecliptic latitude, with the errors in the sense ``computed minus Ulugh Beg''. For the brighter stars (those designated alpha , beta , and gamma in the respective constellations), the mean systematic errors are -11minp 3 +/- 1minp 9 for ecliptic longitude and 9minp 4 +/- 1minp 5 for ecliptic latitude. Within the errors this matches the systematic error in both coordinates for alpha Vir. With greater confidence we may conclude that alpha Vir was the principal reference star in the catalogues of Ulugh Beg and Ptolemy. Evans, J. 1987, J. Hist. Astr. 18, 155. Knobel, E. B. 1917, Ulugh Beg's Catalogue of Stars, Washington, D. C.: Carnegie Institution. Shevchenko, M. 1990, J. Hist. Astr. 21, 187.
Stannard, David L.; Rosenberry, Donald O.; Winter, Thomas C.; Parkhurst, Renee S.
2004-01-01
Micrometeorological measurements of evapotranspiration (ET) often are affected to some degree by errors arising from limited fetch. A recently developed model was used to estimate fetch-induced errors in Bowen-ratio energy-budget measurements of ET made at a small wetland with fetch-to-height ratios ranging from 34 to 49. Estimated errors were small, averaging −1.90%±0.59%. The small errors are attributed primarily to the near-zero lower sensor height, and the negative bias reflects the greater Bowen ratios of the drier surrounding upland. Some of the variables and parameters affecting the error were not measured, but instead are estimated. A sensitivity analysis indicates that the uncertainty arising from these estimates is small. In general, fetch-induced error in measured wetland ET increases with decreasing fetch-to-height ratio, with increasing aridity and with increasing atmospheric stability over the wetland. Occurrence of standing water at a site is likely to increase the appropriate time step of data integration, for a given level of accuracy. Occurrence of extensive open water can increase accuracy or decrease the required fetch by allowing the lower sensor to be placed at the water surface. If fetch is highly variable and fetch-induced errors are significant, the variables affecting fetch (e.g., wind direction, water level) need to be measured. Fetch-induced error during the non-growing season may be greater or smaller than during the growing season, depending on how seasonal changes affect both the wetland and upland at a site.
NASA Technical Reports Server (NTRS)
Yang, Song; Olson, William S.; Wang, Jian-Jian; Bell, Thomas L.; Smith, Eric A.; Kummerow, Christian D.
2006-01-01
Rainfall rate estimates from spaceborne microwave radiometers are generally accepted as reliable by a majority of the atmospheric science community. One of the Tropical Rainfall Measuring Mission (TRMM) facility rain-rate algorithms is based upon passive microwave observations from the TRMM Microwave Imager (TMI). In Part I of this series, improvements of the TMI algorithm that are required to introduce latent heating as an additional algorithm product are described. Here, estimates of surface rain rate, convective proportion, and latent heating are evaluated using independent ground-based estimates and satellite products. Instantaneous, 0.5 deg. -resolution estimates of surface rain rate over ocean from the improved TMI algorithm are well correlated with independent radar estimates (r approx. 0.88 over the Tropics), but bias reduction is the most significant improvement over earlier algorithms. The bias reduction is attributed to the greater breadth of cloud-resolving model simulations that support the improved algorithm and the more consistent and specific convective/stratiform rain separation method utilized. The bias of monthly 2.5 -resolution estimates is similarly reduced, with comparable correlations to radar estimates. Although the amount of independent latent heating data is limited, TMI-estimated latent heating profiles compare favorably with instantaneous estimates based upon dual-Doppler radar observations, and time series of surface rain-rate and heating profiles are generally consistent with those derived from rawinsonde analyses. Still, some biases in profile shape are evident, and these may be resolved with (a) additional contextual information brought to the estimation problem and/or (b) physically consistent and representative databases supporting the algorithm. A model of the random error in instantaneous 0.5 deg. -resolution rain-rate estimates appears to be consistent with the levels of error determined from TMI comparisons with collocated radar. Error model modifications for nonraining situations will be required, however. Sampling error represents only a portion of the total error in monthly 2.5 -resolution TMI estimates; the remaining error is attributed to random and systematic algorithm errors arising from the physical inconsistency and/or nonrepresentativeness of cloud-resolving-model-simulated profiles that support the algorithm.
Unaccounted source of systematic errors in measurements of the Newtonian gravitational constant G
NASA Astrophysics Data System (ADS)
DeSalvo, Riccardo
2015-06-01
Many precision measurements of G have produced a spread of results incompatible with measurement errors. Clearly an unknown source of systematic errors is at work. It is proposed here that most of the discrepancies derive from subtle deviations from Hooke's law, caused by avalanches of entangled dislocations. The idea is supported by deviations from linearity reported by experimenters measuring G, similarly to what is observed, on a larger scale, in low-frequency spring oscillators. Some mitigating experimental apparatus modifications are suggested.
13Check_RNA: A tool to evaluate 13C chemical shifts assignments of RNA.
Icazatti, A A; Martin, O A; Villegas, M; Szleifer, I; Vila, J A
2018-06-19
Chemical shifts (CS) are an important source of structural information of macromolecules such as RNA. In addition to the scarce availability of CS for RNA, the observed values are prone to errors due to a wrong re-calibration or miss assignments. Different groups have dedicated their efforts to correct CS systematic errors on RNA. Despite this, there are not automated and freely available algorithms for correct assignments of RNA 13C CS before their deposition to the BMRB or re-reference already deposited CS with systematic errors. Based on an existent method we have implemented an open source python module to correct 13C CS (from here on 13Cexp) systematic errors of RNAs and then return the results in 3 formats including the nmrstar one. This software is available on GitHub at https://github.com/BIOS-IMASL/13Check_RNA under a MIT license. Supplementary data are available at Bioinformatics online.
NASA Astrophysics Data System (ADS)
Krisciunas, Kevin
2007-12-01
A gnomon, or vertical pointed stick, can be used to determine the north-south direction at a site, as well as one's latitude. If one has accurate time and knows one's time zone, it is also possible to determine one's longitude. From observations on the first day of winter and the first day of summer one can determine the obliquity of the ecliptic. Since we can obtain accurate geographical coordinates from Google Earth or a GPS device, analysis of set of shadow length measurements can be used by students to learn about astronomical coordinate systems, time systems, systematic errors, and random errors. Systematic latitude errors of student datasets are typically 30 nautical miles (0.5 degree) or more, but with care one can achieve systematic and random errors less than 8 nautical miles. One of the advantages of this experiment is that it can be carried out during the day. Also, it is possible to determine if a student has made up his data.
NASA Technical Reports Server (NTRS)
Timofeyev, Y. M.
1979-01-01
In order to test the error of calculation in assumed values of the transmission function for Soviet and American radiometers sounding the atmosphere thermally from orbiting satellites, the assumptions of the transmission calculation is varied with respect to atmospheric CO2 content, transmission frequency, and atmospheric absorption. The error arising from variations of the assumptions from the standard basic model is calculated.
Measures of Linguistic Accuracy in Second Language Writing Research.
ERIC Educational Resources Information Center
Polio, Charlene G.
1997-01-01
Investigates the reliability of measures of linguistic accuracy in second language writing. The study uses a holistic scale, error-free T-units, and an error classification system on the essays of English-as-a-Second-Language students and discusses why disagreements arise within a rater and between raters. (24 references) (Author/CK)
NASA Astrophysics Data System (ADS)
Xu, Chong-yu; Tunemar, Liselotte; Chen, Yongqin David; Singh, V. P.
2006-06-01
Sensitivity of hydrological models to input data errors have been reported in the literature for particular models on a single or a few catchments. A more important issue, i.e. how model's response to input data error changes as the catchment conditions change has not been addressed previously. This study investigates the seasonal and spatial effects of precipitation data errors on the performance of conceptual hydrological models. For this study, a monthly conceptual water balance model, NOPEX-6, was applied to 26 catchments in the Mälaren basin in Central Sweden. Both systematic and random errors were considered. For the systematic errors, 5-15% of mean monthly precipitation values were added to the original precipitation to form the corrupted input scenarios. Random values were generated by Monte Carlo simulation and were assumed to be (1) independent between months, and (2) distributed according to a Gaussian law of zero mean and constant standard deviation that were taken as 5, 10, 15, 20, and 25% of the mean monthly standard deviation of precipitation. The results show that the response of the model parameters and model performance depends, among others, on the type of the error, the magnitude of the error, physical characteristics of the catchment, and the season of the year. In particular, the model appears less sensitive to the random error than to the systematic error. The catchments with smaller values of runoff coefficients were more influenced by input data errors than were the catchments with higher values. Dry months were more sensitive to precipitation errors than were wet months. Recalibration of the model with erroneous data compensated in part for the data errors by altering the model parameters.
Detecting and overcoming systematic errors in genome-scale phylogenies.
Rodríguez-Ezpeleta, Naiara; Brinkmann, Henner; Roure, Béatrice; Lartillot, Nicolas; Lang, B Franz; Philippe, Hervé
2007-06-01
Genome-scale data sets result in an enhanced resolution of the phylogenetic inference by reducing stochastic errors. However, there is also an increase of systematic errors due to model violations, which can lead to erroneous phylogenies. Here, we explore the impact of systematic errors on the resolution of the eukaryotic phylogeny using a data set of 143 nuclear-encoded proteins from 37 species. The initial observation was that, despite the impressive amount of data, some branches had no significant statistical support. To demonstrate that this lack of resolution is due to a mutual annihilation of phylogenetic and nonphylogenetic signals, we created a series of data sets with slightly different taxon sampling. As expected, these data sets yielded strongly supported but mutually exclusive trees, thus confirming the presence of conflicting phylogenetic and nonphylogenetic signals in the original data set. To decide on the correct tree, we applied several methods expected to reduce the impact of some kinds of systematic error. Briefly, we show that (i) removing fast-evolving positions, (ii) recoding amino acids into functional categories, and (iii) using a site-heterogeneous mixture model (CAT) are three effective means of increasing the ratio of phylogenetic to nonphylogenetic signal. Finally, our results allow us to formulate guidelines for detecting and overcoming phylogenetic artefacts in genome-scale phylogenetic analyses.
Systematic biases in group decision-making: implications for patient safety.
Mannion, Russell; Thompson, Carl
2014-12-01
Key decisions in modern health care systems are often made by groups of people rather than lone individuals. However, group decision-making can be imperfect and result in organizational and clinical errors which may harm patients-a fact highlighted graphically in recent (and historical) health scandals and inquiries such as the recent report by Sir Robert Francis into the serious failures in patient care and safety at Mid Staffordshire Hospitals NHS Trust in the English NHS. In this article, we draw on theories from organization studies and decision science to explore the ways in which patient safety may be undermined or threatened in health care contexts as a result of four systematic biases arising from group decision-making: 'groupthink', 'social loafing', 'group polarization' and 'escalation of commitment'. For each group bias, we describe its antecedents, illustrate how it can impair group decisions with regard to patient safety, outline a range of possible remedial organizational strategies that can be used to attenuate the potential for adverse consequences and look forward at the emerging research agenda in this important but hitherto neglected area of patient safety research. © The Author 2014. Published by Oxford University Press in association with the International Society for Quality in Health Care; all rights reserved.
Preimplantation genetic diagnosis: a systematic review of litigation in the face of new technology.
Amagwula, Tochi; Chang, Peter L; Hossain, Amjad; Tyner, Joey; Rivers, Aimée L; Phelps, John Y
2012-11-01
To study legal cases against IVF facilities pertaining to preimplantation genetic diagnosis (PGD) misdiagnosis. Systematic case law review. University medical center using US legal databases. The IVF recipients using PGD services. Lawsuits pertaining to PGD against IVF facilities. Lawsuits, court rulings, damage awards, and settlements pertaining to PGD after the birth of a child with a genetic defect. Causes of action pertaining to PGD arise from negligence in performing the procedure as well as failure to properly inform patients of key information, such as inherent errors associated with the PGD process, a facility's minimal experience in performing PGD, and the option of obtaining PGD. Courts have sympathized with the financial burden involved in caring for children with disabilities. Monetary damage awards are based on the costs of caring for children with debilitating defects, including lifetime medical and custodial care. Facilities offering PGD services expose themselves to a new realm of liability in which damage awards can easily exceed the limits of a facility's insurance policy. Competent laboratory personnel and proper informed consent--with particular care to inform patients of the inherent inaccuracies of PGD--are crucial in helping deter liability. Copyright © 2012 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Stone, Daithi A.; Hansen, Gerrit
Despite being a well-established research field, the detection and attribution of observed climate change to anthropogenic forcing is not yet provided as a climate service. One reason for this is the lack of a methodology for performing tailored detection and attribution assessments on a rapid time scale. Here we develop such an approach, based on the translation of quantitative analysis into the “confidence” language employed in recent Assessment Reports of the Intergovernmental Panel on Climate Change. While its systematic nature necessarily ignores some nuances examined in detailed expert assessments, the approach nevertheless goes beyond most detection and attribution studies inmore » considering contributors to building confidence such as errors in observational data products arising from sparse monitoring networks. When compared against recent expert assessments, the results of this approach closely match those of the existing assessments. Where there are small discrepancies, these variously reflect ambiguities in the details of what is being assessed, reveal nuances or limitations of the expert assessments, or indicate limitations of the accuracy of the sort of systematic approach employed here. Deployment of the method on 116 regional assessments of recent temperature and precipitation changes indicates that existing rules of thumb concerning the detectability of climate change ignore the full range of sources of uncertainty, most particularly the importance of adequate observational monitoring.« less
Local systematic differences in 2MASS positions
NASA Astrophysics Data System (ADS)
Bustos Fierro, I. H.; Calderón, J. H.
2018-01-01
We have found that positions in the 2MASS All-sky Catalog of Point Sources show local systematic differences with characteristic length-scales of ˜ 5 to ˜ 8 arcminutes when compared with several catalogs. We have observed that when 2MASS positions are used in the computation of proper motions, the mentioned systematic differences cause systematic errors in the resulting proper motions. We have developed a method to locally rectify 2MASS with respect to UCAC4 in order to diminish the systematic differences between these catalogs. The rectified 2MASS catalog with the proposed method can be regarded as an extension of UCAC4 for astrometry with accuracy ˜ 90 mas in its positions, with negligible systematic errors. Also we show that the use of these rectified positions removes the observed systematic pattern in proper motions derived from original 2MASS positions.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Keeling, V; Jin, H; Hossain, S
2014-06-15
Purpose: To evaluate setup accuracy and quantify individual systematic and random errors for the various hardware and software components of the frameless 6D-BrainLAB ExacTrac system. Methods: 35 patients with cranial lesions, some with multiple isocenters (50 total lesions treated in 1, 3, 5 fractions), were investigated. All patients were simulated with a rigid head-and-neck mask and the BrainLAB localizer. CT images were transferred to the IPLAN treatment planning system where optimized plans were generated using stereotactic reference frame based on the localizer. The patients were setup initially with infrared (IR) positioning ExacTrac system. Stereoscopic X-ray images (XC: X-ray Correction) weremore » registered to their corresponding digitally-reconstructed-radiographs, based on bony anatomy matching, to calculate 6D-translational and rotational (Lateral, Longitudinal, Vertical, Pitch, Roll, Yaw) shifts. XC combines systematic errors of the mask, localizer, image registration, frame, and IR. If shifts were below tolerance (0.7 mm translational and 1 degree rotational), treatment was initiated; otherwise corrections were applied and additional X-rays were acquired to verify patient position (XV: X-ray Verification). Statistical analysis was used to extract systematic and random errors of the different components of the 6D-ExacTrac system and evaluate the cumulative setup accuracy. Results: Mask systematic errors (translational; rotational) were the largest and varied from one patient to another in the range (−15 to 4mm; −2.5 to 2.5degree) obtained from mean of XC for each patient. Setup uncertainty in IR positioning (0.97,2.47,1.62mm;0.65,0.84,0.96degree) was extracted from standard-deviation of XC. Combined systematic errors of the frame and localizer (0.32,−0.42,−1.21mm; −0.27,0.34,0.26degree) was extracted from mean of means of XC distributions. Final patient setup uncertainty was obtained from the standard deviations of XV (0.57,0.77,0.67mm,0.39,0.35,0.30degree). Conclusion: Statistical analysis was used to calculate cumulative and individual systematic errors from the different hardware and software components of the 6D-ExacTrac-system. Patients were treated with cumulative errors (<1mm,<1degree) with XV image guidance.« less
NASA Astrophysics Data System (ADS)
Brousmiche, S.; Souris, K.; Orban de Xivry, J.; Lee, J. A.; Macq, B.; Seco, J.
2017-11-01
Proton range random and systematic uncertainties are the major factors undermining the advantages of proton therapy, namely, a sharp dose falloff and a better dose conformality for lower doses in normal tissues. The influence of CT artifacts such as beam hardening or scatter can easily be understood and estimated due to their large-scale effects on the CT image, like cupping and streaks. In comparison, the effects of weakly-correlated stochastic noise are more insidious and less attention is drawn on them partly due to the common belief that they only contribute to proton range uncertainties and not to systematic errors thanks to some averaging effects. A new source of systematic errors on the range and relative stopping powers (RSP) has been highlighted and proved not to be negligible compared to the 3.5% uncertainty reference value used for safety margin design. Hence, we demonstrate that the angular points in the HU-to-RSP calibration curve are an intrinsic source of proton range systematic error for typical levels of zero-mean stochastic CT noise. Systematic errors on RSP of up to 1% have been computed for these levels. We also show that the range uncertainty does not generally vary linearly with the noise standard deviation. We define a noise-dependent effective calibration curve that better describes, for a given material, the RSP value that is actually used. The statistics of the RSP and the range continuous slowing down approximation (CSDA) have been analytically derived for the general case of a calibration curve obtained by the stoichiometric calibration procedure. These models have been validated against actual CSDA simulations for homogeneous and heterogeneous synthetical objects as well as on actual patient CTs for prostate and head-and-neck treatment planning situations.
Medication errors in the Middle East countries: a systematic review of the literature.
Alsulami, Zayed; Conroy, Sharon; Choonara, Imti
2013-04-01
Medication errors are a significant global concern and can cause serious medical consequences for patients. Little is known about medication errors in Middle Eastern countries. The objectives of this systematic review were to review studies of the incidence and types of medication errors in Middle Eastern countries and to identify the main contributory factors involved. A systematic review of the literature related to medication errors in Middle Eastern countries was conducted in October 2011 using the following databases: Embase, Medline, Pubmed, the British Nursing Index and the Cumulative Index to Nursing & Allied Health Literature. The search strategy included all ages and languages. Inclusion criteria were that the studies assessed or discussed the incidence of medication errors and contributory factors to medication errors during the medication treatment process in adults or in children. Forty-five studies from 10 of the 15 Middle Eastern countries met the inclusion criteria. Nine (20 %) studies focused on medication errors in paediatric patients. Twenty-one focused on prescribing errors, 11 measured administration errors, 12 were interventional studies and one assessed transcribing errors. Dispensing and documentation errors were inadequately evaluated. Error rates varied from 7.1 % to 90.5 % for prescribing and from 9.4 % to 80 % for administration. The most common types of prescribing errors reported were incorrect dose (with an incidence rate from 0.15 % to 34.8 % of prescriptions), wrong frequency and wrong strength. Computerised physician rder entry and clinical pharmacist input were the main interventions evaluated. Poor knowledge of medicines was identified as a contributory factor for errors by both doctors (prescribers) and nurses (when administering drugs). Most studies did not assess the clinical severity of the medication errors. Studies related to medication errors in the Middle Eastern countries were relatively few in number and of poor quality. Educational programmes on drug therapy for doctors and nurses are urgently needed.
Patient disclosure of medical errors in paediatrics: A systematic literature review
Koller, Donna; Rummens, Anneke; Le Pouesard, Morgane; Espin, Sherry; Friedman, Jeremy; Coffey, Maitreya; Kenneally, Noah
2016-01-01
Medical errors are common within paediatrics; however, little research has examined the process of disclosing medical errors in paediatric settings. The present systematic review of current research and policy initiatives examined evidence regarding the disclosure of medical errors involving paediatric patients. Peer-reviewed research from a range of scientific journals from the past 10 years is presented, and an overview of Canadian and international policies regarding disclosure in paediatric settings are provided. The purpose of the present review was to scope the existing literature and policy, and to synthesize findings into an integrated and accessible report. Future research priorities and policy implications are then identified. PMID:27429578
System calibration method for Fourier ptychographic microscopy
NASA Astrophysics Data System (ADS)
Pan, An; Zhang, Yan; Zhao, Tianyu; Wang, Zhaojun; Dan, Dan; Lei, Ming; Yao, Baoli
2017-09-01
Fourier ptychographic microscopy (FPM) is a recently proposed computational imaging technique with both high-resolution and wide field of view. In current FPM imaging platforms, systematic error sources come from aberrations, light-emitting diode (LED) intensity fluctuation, parameter imperfections, and noise, all of which may severely corrupt the reconstruction results with similar artifacts. Therefore, it would be unlikely to distinguish the dominating error from these degraded reconstructions without any preknowledge. In addition, systematic error is generally a mixture of various error sources in the real situation, and it cannot be separated due to their mutual restriction and conversion. To this end, we report a system calibration procedure, termed SC-FPM, to calibrate the mixed systematic errors simultaneously from an overall perspective, based on the simulated annealing algorithm, the LED intensity correction method, the nonlinear regression process, and the adaptive step-size strategy, which involves the evaluation of an error metric at each iteration step, followed by the re-estimation of accurate parameters. The performance achieved both in simulations and experiments demonstrates that the proposed method outperforms other state-of-the-art algorithms. The reported system calibration scheme improves the robustness of FPM, relaxes the experiment conditions, and does not require any preknowledge, which makes the FPM more pragmatic.
Li, T. S.; DePoy, D. L.; Marshall, J. L.; ...
2016-06-01
Here, we report that meeting the science goals for many current and future ground-based optical large-area sky surveys requires that the calibrated broadband photometry is both stable in time and uniform over the sky to 1% precision or better. Past and current surveys have achieved photometric precision of 1%–2% by calibrating the survey's stellar photometry with repeated measurements of a large number of stars observed in multiple epochs. The calibration techniques employed by these surveys only consider the relative frame-by-frame photometric zeropoint offset and the focal plane position-dependent illumination corrections, which are independent of the source color. However, variations inmore » the wavelength dependence of the atmospheric transmission and the instrumental throughput induce source color-dependent systematic errors. These systematic errors must also be considered to achieve the most precise photometric measurements. In this paper, we examine such systematic chromatic errors (SCEs) using photometry from the Dark Energy Survey (DES) as an example. We first define a natural magnitude system for DES and calculate the systematic errors on stellar magnitudes when the atmospheric transmission and instrumental throughput deviate from the natural system. We conclude that the SCEs caused by the change of airmass in each exposure, the change of the precipitable water vapor and aerosol in the atmosphere over time, and the non-uniformity of instrumental throughput over the focal plane can be up to 2% in some bandpasses. We then compare the calculated SCEs with the observed DES data. For the test sample data, we correct these errors using measurements of the atmospheric transmission and instrumental throughput from auxiliary calibration systems. In conclusion, the residual after correction is less than 0.3%. Moreover, we calculate such SCEs for Type Ia supernovae and elliptical galaxies and find that the chromatic errors for non-stellar objects are redshift-dependent and can be larger than those for stars at certain redshifts.« less
Systematic error of diode thermometer.
Iskrenovic, Predrag S
2009-08-01
Semiconductor diodes are often used for measuring temperatures. The forward voltage across a diode decreases, approximately linearly, with the increase in temperature. The applied method is mainly the simplest one. A constant direct current flows through the diode, and voltage is measured at diode terminals. The direct current that flows through the diode, putting it into operating mode, heats up the diode. The increase in temperature of the diode-sensor, i.e., the systematic error due to self-heating, depends on the intensity of current predominantly and also on other factors. The results of systematic error measurements due to heating up by the forward-bias current have been presented in this paper. The measurements were made at several diodes over a wide range of bias current intensity.
Hadronic Contribution to Muon g-2 with Systematic Error Correlations
NASA Astrophysics Data System (ADS)
Brown, D. H.; Worstell, W. A.
1996-05-01
We have performed a new evaluation of the hadronic contribution to a_μ=(g-2)/2 of the muon with explicit correlations of systematic errors among the experimental data on σ( e^+e^- → hadrons ). Our result for the lowest order hadronic vacuum polarization contribution is a_μ^hvp = 701.7(7.6)(13.4) × 10-10 where the total systematic error contributions from below and above √s = 1.4 GeV are (12.5) × 10-10 and (4.8) × 10-10 respectively. Therefore new measurements on σ( e^+e^- → hadrons ) below 1.4 GeV in Novosibirsk, Russia can significantly reduce the total error on a_μ^hvp. This contrasts with a previous evaluation which indicated that the dominant error is due to the energy region above 1.4 GeV. The latter analysis correlated systematic errors at each energy point separately but not across energy ranges as we have done. Combination with higher order hadronic contributions is required for a new measurement of a_μ at Brookhaven National Laboratory to be sensitive to electroweak and possibly supergravity and muon substructure effects. Our analysis may also be applied to calculations of hadronic contributions to the running of α(s) at √s= M_Z, the hyperfine structure of muonium, and the running of sin^2 θW in Møller scattering. The analysis of the new Novosibirsk data will also be given.
Small, J R
1993-01-01
This paper is a study into the effects of experimental error on the estimated values of flux control coefficients obtained using specific inhibitors. Two possible techniques for analysing the experimental data are compared: a simple extrapolation method (the so-called graph method) and a non-linear function fitting method. For these techniques, the sources of systematic errors are identified and the effects of systematic and random errors are quantified, using both statistical analysis and numerical computation. It is shown that the graph method is very sensitive to random errors and, under all conditions studied, that the fitting method, even under conditions where the assumptions underlying the fitted function do not hold, outperformed the graph method. Possible ways of designing experiments to minimize the effects of experimental errors are analysed and discussed. PMID:8257434
Real-time auto-adaptive margin generation for MLC-tracked radiotherapy
NASA Astrophysics Data System (ADS)
Glitzner, M.; Fast, M. F.; de Senneville, B. Denis; Nill, S.; Oelfke, U.; Lagendijk, J. J. W.; Raaymakers, B. W.; Crijns, S. P. M.
2017-01-01
In radiotherapy, abdominal and thoracic sites are candidates for performing motion tracking. With real-time control it is possible to adjust the multileaf collimator (MLC) position to the target position. However, positions are not perfectly matched and position errors arise from system delays and complicated response of the electromechanic MLC system. Although, it is possible to compensate parts of these errors by using predictors, residual errors remain and need to be compensated to retain target coverage. This work presents a method to statistically describe tracking errors and to automatically derive a patient-specific, per-segment margin to compensate the arising underdosage on-line, i.e. during plan delivery. The statistics of the geometric error between intended and actual machine position are derived using kernel density estimators. Subsequently a margin is calculated on-line according to a selected coverage parameter, which determines the amount of accepted underdosage. The margin is then applied onto the actual segment to accommodate the positioning errors in the enlarged segment. The proof-of-concept was tested in an on-line tracking experiment and showed the ability to recover underdosages for two test cases, increasing {{V}90 %} in the underdosed area about 47 % and 41 % , respectively. The used dose model was able to predict the loss of dose due to tracking errors and could be used to infer the necessary margins. The implementation had a running time of 23 ms which is compatible with real-time requirements of MLC tracking systems. The auto-adaptivity to machine and patient characteristics makes the technique a generic yet intuitive candidate to avoid underdosages due to MLC tracking errors.
Erring and learning in clinical practice.
Hurwitz, Brian
2002-01-01
This paper discusses error type their possible consequences and the doctors who make them. There is no single, all-encompassing typology of medical errors. They are frequently multifactorial in origin and use from the mental processes of individuals; from defects in perception, thinking reasoning planning and interpretation and from failures of team-working omissions and poorly executed actions. They also arise from inadequately designed and operated healthcare systems or procedures. The paper considers error-truth relatedness, the approach of UK courts to medical errors, the learning opportunities which flow from error recognition and the need for personal and professional self awareness of clinical fallibilities. PMID:12389767
León-Reina, L; García-Maté, M; Álvarez-Pinazo, G; Santacruz, I; Vallcorba, O; De la Torre, A G; Aranda, M A G
2016-06-01
This study reports 78 Rietveld quantitative phase analyses using Cu K α 1 , Mo K α 1 and synchrotron radiations. Synchrotron powder diffraction has been used to validate the most challenging analyses. From the results for three series with increasing contents of an analyte (an inorganic crystalline phase, an organic crystalline phase and a glass), it is inferred that Rietveld analyses from high-energy Mo K α 1 radiation have slightly better accuracies than those obtained from Cu K α 1 radiation. This behaviour has been established from the results of the calibration graphics obtained through the spiking method and also from Kullback-Leibler distance statistic studies. This outcome is explained, in spite of the lower diffraction power for Mo radiation when compared to Cu radiation, as arising because of the larger volume tested with Mo and also because higher energy allows one to record patterns with fewer systematic errors. The limit of detection (LoD) and limit of quantification (LoQ) have also been established for the studied series. For similar recording times, the LoDs in Cu patterns, ∼0.2 wt%, are slightly lower than those derived from Mo patterns, ∼0.3 wt%. The LoQ for a well crystallized inorganic phase using laboratory powder diffraction was established to be close to 0.10 wt% in stable fits with good precision. However, the accuracy of these analyses was poor with relative errors near to 100%. Only contents higher than 1.0 wt% yielded analyses with relative errors lower than 20%.
Combined influence of visual scene and body tilt on arm pointing movements: gravity matters!
Scotto Di Cesare, Cécile; Sarlegna, Fabrice R; Bourdin, Christophe; Mestre, Daniel R; Bringoux, Lionel
2014-01-01
Performing accurate actions such as goal-directed arm movements requires taking into account visual and body orientation cues to localize the target in space and produce appropriate reaching motor commands. We experimentally tilted the body and/or the visual scene to investigate how visual and body orientation cues are combined for the control of unseen arm movements. Subjects were asked to point toward a visual target using an upward movement during slow body and/or visual scene tilts. When the scene was tilted, final pointing errors varied as a function of the direction of the scene tilt (forward or backward). Actual forward body tilt resulted in systematic target undershoots, suggesting that the brain may have overcompensated for the biomechanical movement facilitation arising from body tilt. Combined body and visual scene tilts also affected final pointing errors according to the orientation of the visual scene. The data were further analysed using either a body-centered or a gravity-centered reference frame to encode visual scene orientation with simple additive models (i.e., 'combined' tilts equal to the sum of 'single' tilts). We found that the body-centered model could account only for some of the data regarding kinematic parameters and final errors. In contrast, the gravity-centered modeling in which the body and visual scene orientations were referred to vertical could explain all of these data. Therefore, our findings suggest that the brain uses gravity, thanks to its invariant properties, as a reference for the combination of visual and non-visual cues.
Combined Influence of Visual Scene and Body Tilt on Arm Pointing Movements: Gravity Matters!
Scotto Di Cesare, Cécile; Sarlegna, Fabrice R.; Bourdin, Christophe; Mestre, Daniel R.; Bringoux, Lionel
2014-01-01
Performing accurate actions such as goal-directed arm movements requires taking into account visual and body orientation cues to localize the target in space and produce appropriate reaching motor commands. We experimentally tilted the body and/or the visual scene to investigate how visual and body orientation cues are combined for the control of unseen arm movements. Subjects were asked to point toward a visual target using an upward movement during slow body and/or visual scene tilts. When the scene was tilted, final pointing errors varied as a function of the direction of the scene tilt (forward or backward). Actual forward body tilt resulted in systematic target undershoots, suggesting that the brain may have overcompensated for the biomechanical movement facilitation arising from body tilt. Combined body and visual scene tilts also affected final pointing errors according to the orientation of the visual scene. The data were further analysed using either a body-centered or a gravity-centered reference frame to encode visual scene orientation with simple additive models (i.e., ‘combined’ tilts equal to the sum of ‘single’ tilts). We found that the body-centered model could account only for some of the data regarding kinematic parameters and final errors. In contrast, the gravity-centered modeling in which the body and visual scene orientations were referred to vertical could explain all of these data. Therefore, our findings suggest that the brain uses gravity, thanks to its invariant properties, as a reference for the combination of visual and non-visual cues. PMID:24925371
Acoustic evidence for phonologically mismatched speech errors.
Gormley, Andrea
2015-04-01
Speech errors are generally said to accommodate to their new phonological context. This accommodation has been validated by several transcription studies. The transcription methodology is not the best choice for detecting errors at this level, however, as this type of error can be difficult to perceive. This paper presents an acoustic analysis of speech errors that uncovers non-accommodated or mismatch errors. A mismatch error is a sub-phonemic error that results in an incorrect surface phonology. This type of error could arise during the processing of phonological rules or they could be made at the motor level of implementation. The results of this work have important implications for both experimental and theoretical research. For experimentalists, it validates the tools used for error induction and the acoustic determination of errors free of the perceptual bias. For theorists, this methodology can be used to test the nature of the processes proposed in language production.
Adverse effects in dual-feed interferometry
NASA Astrophysics Data System (ADS)
Colavita, M. Mark
2009-11-01
Narrow-angle dual-star interferometric astrometry can provide very high accuracy in the presence of the Earth's turbulent atmosphere. However, to exploit the high atmospherically-limited accuracy requires control of systematic errors in measurement of the interferometer baseline, internal OPDs, and fringe phase. In addition, as high photometric SNR is required, care must be taken to maximize throughput and coherence to obtain high accuracy on faint stars. This article reviews the key aspects of the dual-star approach and implementation, the main contributors to the systematic error budget, and the coherence terms in the photometric error budget.
Efficient Solar Scene Wavefront Estimation with Reduced Systematic and RMS Errors: Summary
NASA Astrophysics Data System (ADS)
Anugu, N.; Garcia, P.
2016-04-01
Wave front sensing for solar telescopes is commonly implemented with the Shack-Hartmann sensors. Correlation algorithms are usually used to estimate the extended scene Shack-Hartmann sub-aperture image shifts or slopes. The image shift is computed by correlating a reference sub-aperture image with the target distorted sub-aperture image. The pixel position where the maximum correlation is located gives the image shift in integer pixel coordinates. Sub-pixel precision image shifts are computed by applying a peak-finding algorithm to the correlation peak Poyneer (2003); Löfdahl (2010). However, the peak-finding algorithm results are usually biased towards the integer pixels, these errors are called as systematic bias errors Sjödahl (1994). These errors are caused due to the low pixel sampling of the images. The amplitude of these errors depends on the type of correlation algorithm and the type of peak-finding algorithm being used. To study the systematic errors in detail, solar sub-aperture synthetic images are constructed by using a Swedish Solar Telescope solar granulation image1. The performance of cross-correlation algorithm in combination with different peak-finding algorithms is investigated. The studied peak-finding algorithms are: parabola Poyneer (2003); quadratic polynomial Löfdahl (2010); threshold center of gravity Bailey (2003); Gaussian Nobach & Honkanen (2005) and Pyramid Bailey (2003). The systematic error study reveals that that the pyramid fit is the most robust to pixel locking effects. The RMS error analysis study reveals that the threshold centre of gravity behaves better in low SNR, although the systematic errors in the measurement are large. It is found that no algorithm is best for both the systematic and the RMS error reduction. To overcome the above problem, a new solution is proposed. In this solution, the image sampling is increased prior to the actual correlation matching. The method is realized in two steps to improve its computational efficiency. In the first step, the cross-correlation is implemented at the original image spatial resolution grid (1 pixel). In the second step, the cross-correlation is performed using a sub-pixel level grid by limiting the field of search to 4 × 4 pixels centered at the first step delivered initial position. The generation of these sub-pixel grid based region of interest images is achieved with the bi-cubic interpolation. The correlation matching with sub-pixel grid technique was previously reported in electronic speckle photography Sjö'dahl (1994). This technique is applied here for the solar wavefront sensing. A large dynamic range and a better accuracy in the measurements are achieved with the combination of the original pixel grid based correlation matching in a large field of view and a sub-pixel interpolated image grid based correlation matching within a small field of view. The results revealed that the proposed method outperforms all the different peak-finding algorithms studied in the first approach. It reduces both the systematic error and the RMS error by a factor of 5 (i.e., 75% systematic error reduction), when 5 times improved image sampling was used. This measurement is achieved at the expense of twice the computational cost. With the 5 times improved image sampling, the wave front accuracy is increased by a factor of 5. The proposed solution is strongly recommended for wave front sensing in the solar telescopes, particularly, for measuring large dynamic image shifts involved open loop adaptive optics. Also, by choosing an appropriate increment of image sampling in trade-off between the computational speed limitation and the aimed sub-pixel image shift accuracy, it can be employed in closed loop adaptive optics. The study is extended to three other class of sub-aperture images (a point source; a laser guide star; a Galactic Center extended scene). The results are planned to submit for the Optical Express journal.
Cross-correlation of point series using a new method
NASA Technical Reports Server (NTRS)
Strothers, Richard B.
1994-01-01
Traditional methods of cross-correlation of two time series do not apply to point time series. Here, a new method, devised specifically for point series, utilizes a correlation measure that is based in the rms difference (or, alternatively, the median absolute difference) between nearest neightbors in overlapped segments of the two series. Error estimates for the observed locations of the points, as well as a systematic shift of one series with respect to the other to accommodate a constant, but unknown, lead or lag, are easily incorporated into the analysis using Monte Carlo techniques. A methodological restriction adopted here is that one series be treated as a template series against which the other, called the target series, is cross-correlated. To estimate a significance level for the correlation measure, the adopted alternative (null) hypothesis is that the target series arises from a homogeneous Poisson process. The new method is applied to cross-correlating the times of the greatest geomagnetic storms with the times of maximum in the undecennial solar activity cycle.
Demonstration of a Sensitive Method to Measure Nuclear-Spin-Dependent Parity Violation
NASA Astrophysics Data System (ADS)
Altuntaş, Emine; Ammon, Jeffrey; Cahn, Sidney B.; DeMille, David
2018-04-01
Nuclear-spin-dependent parity violation (NSD-PV) effects in atoms and molecules arise from Z0 boson exchange between electrons and the nucleus, and from the magnetic interaction between electrons and the parity-violating nuclear anapole moment. We demonstrate measurements of NSD-PV that use an enhancement of the effect in diatomic molecules, here using the test system 138Ba 19. Our sensitivity surpasses that of any previous atomic parity violation measurement. We show that systematic errors can be suppressed to at least the level of the present statistical sensitivity. We measure the matrix element W of the NSD-PV interaction with total uncertainty δ W /(2 π )<0.7 Hz , for each of two configurations where W must have different signs. This sensitivity would be sufficient to measure NSD-PV effects of the size anticipated across a wide range of nuclei including 137Ba in 137BaF, where |W |/(2 π )≈5 Hz is expected.
Equation of state and QCD transition at finite temperature
NASA Astrophysics Data System (ADS)
Bazavov, A.; Bhattacharya, T.; Cheng, M.; Christ, N. H.; Detar, C.; Ejiri, S.; Gottlieb, Steven; Gupta, R.; Heller, U. M.; Huebner, K.; Jung, C.; Karsch, F.; Laermann, E.; Levkova, L.; Miao, C.; Mawhinney, R. D.; Petreczky, P.; Schmidt, C.; Soltz, R. A.; Soeldner, W.; Sugar, R.; Toussaint, D.; Vranas, P.
2009-07-01
We calculate the equation of state in 2+1 flavor QCD at finite temperature with physical strange quark mass and almost physical light quark masses using lattices with temporal extent Nτ=8. Calculations have been performed with two different improved staggered fermion actions, the asqtad and p4 actions. Overall, we find good agreement between results obtained with these two O(a2) improved staggered fermion discretization schemes. A comparison with earlier calculations on coarser lattices is performed to quantify systematic errors in current studies of the equation of state. We also present results for observables that are sensitive to deconfining and chiral aspects of the QCD transition on Nτ=6 and 8 lattices. We find that deconfinement and chiral symmetry restoration happen in the same narrow temperature interval. In an appendix we present a simple parametrization of the equation of state that can easily be used in hydrodynamic model calculations. In this parametrization we include an estimate of current uncertainties in the lattice calculations which arise from cutoff and quark mass effects.
NASA Astrophysics Data System (ADS)
Cunha, Márcio M.; Fonseca, E. A.; Moreno, M. G. M.; Parisio, Fernando
2017-10-01
Channels composed by Einstein-Podolsky-Rosen (EPR) pairs are capable of teleporting arbitrary multipartite states. The question arises whether EPR channels are also optimal against imperfections. In particular, the teleportation of Greenberger-Horne-Zeilinger states (GHZ) requires three EPR states as the channel and full measurements in the Bell basis. We show that, by using two GHZ states as the channel, it is possible to transport any unknown three-qubit state of the form c_0|000\\rangle +c_1|111\\rangle . The teleportation is made through measurements in the GHZ basis, and, to obtain deterministic results, in most of the investigated scenarios, four out of the eight elements of the basis need to be unambiguously distinguished. Most importantly, we show that when both systematic errors and noise are considered, the fidelity of the teleportation protocol is higher when a GHZ channel is used in comparison with that of a channel composed by EPR pairs.
Assessing Model Fitting of Megamaser Disks with Simulated Observations
NASA Astrophysics Data System (ADS)
Han, Jiwon; Braatz, James; Pesce, Dominic
2018-01-01
The Megamaser Cosmology Project (MCP) measures the Hubble Constant by determining distances to galaxies with observations of 22 GHz H20 megamasers. The megamasers arise in the circumnuclear accretion disks of active galaxies. In this research, we aim to improve the estimation of systematic errors in MCP measurements. Currently, the MCP fits a disk model to the observed maser data with a Markov Chain Monte Carlo (MCMC) code. The disk model is described by up to 14 global parameters, including up to 6 that describe the disk warping. We first assess the model by generating synthetic datasets in which the locations and dynamics of the maser spots are exactly known, and fitting the model to these data. By doing so, we can also test the effects of unmodeled substructure on the estimated uncertainties. Furthermore, in order to gain better understanding of the physics behind accretion disk warping, we develop a physics-driven model for the warp and test it with the MCMC approach.
Method for revealing biases in precision mass measurements
NASA Astrophysics Data System (ADS)
Vabson, V.; Vendt, R.; Kübarsepp, T.; Noorma, M.
2013-02-01
A practical method for the quantification of systematic errors of large-scale automatic comparators is presented. This method is based on a comparison of the performance of two different comparators. First, the differences of 16 equal partial loads of 1 kg are measured with a high-resolution mass comparator featuring insignificant bias and 1 kg maximum load. At the second stage, a large-scale comparator is tested by using combined loads with known mass differences. Comparing the different results, the biases of any comparator can be easily revealed. These large-scale comparator biases are determined over a 16-month period, and for the 1 kg loads, a typical pattern of biases in the range of ±0.4 mg is observed. The temperature differences recorded inside the comparator concurrently with mass measurements are found to remain within a range of ±30 mK, which obviously has a minor effect on the detected biases. Seasonal variations imply that the biases likely arise mainly due to the functioning of the environmental control at the measurement location.
Exploring Measurement Error with Cookies: A Real and Virtual Approach via Interactive Excel
ERIC Educational Resources Information Center
Sinex, Scott A; Gage, Barbara A.; Beck, Peggy J.
2007-01-01
A simple, guided-inquiry investigation using stacked sandwich cookies is employed to develop a simple linear mathematical model and to explore measurement error by incorporating errors as part of the investigation. Both random and systematic errors are presented. The model and errors are then investigated further by engaging with an interactive…
Uncertainty Analysis of Seebeck Coefficient and Electrical Resistivity Characterization
NASA Technical Reports Server (NTRS)
Mackey, Jon; Sehirlioglu, Alp; Dynys, Fred
2014-01-01
In order to provide a complete description of a materials thermoelectric power factor, in addition to the measured nominal value, an uncertainty interval is required. The uncertainty may contain sources of measurement error including systematic bias error and precision error of a statistical nature. The work focuses specifically on the popular ZEM-3 (Ulvac Technologies) measurement system, but the methods apply to any measurement system. The analysis accounts for sources of systematic error including sample preparation tolerance, measurement probe placement, thermocouple cold-finger effect, and measurement parameters; in addition to including uncertainty of a statistical nature. Complete uncertainty analysis of a measurement system allows for more reliable comparison of measurement data between laboratories.
Characterizing the impact of model error in hydrologic time series recovery inverse problems
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hansen, Scott K.; He, Jiachuan; Vesselinov, Velimir V.
Hydrologic models are commonly over-smoothed relative to reality, owing to computational limitations and to the difficulty of obtaining accurate high-resolution information. When used in an inversion context, such models may introduce systematic biases which cannot be encapsulated by an unbiased “observation noise” term of the type assumed by standard regularization theory and typical Bayesian formulations. Despite its importance, model error is difficult to encapsulate systematically and is often neglected. In this paper, model error is considered for an important class of inverse problems that includes interpretation of hydraulic transients and contaminant source history inference: reconstruction of a time series thatmore » has been convolved against a transfer function (i.e., impulse response) that is only approximately known. Using established harmonic theory along with two results established here regarding triangular Toeplitz matrices, upper and lower error bounds are derived for the effect of systematic model error on time series recovery for both well-determined and over-determined inverse problems. It is seen that use of additional measurement locations does not improve expected performance in the face of model error. A Monte Carlo study of a realistic hydraulic reconstruction problem is presented, and the lower error bound is seen informative about expected behavior. Finally, a possible diagnostic criterion for blind transfer function characterization is also uncovered.« less
Characterizing the impact of model error in hydrologic time series recovery inverse problems
Hansen, Scott K.; He, Jiachuan; Vesselinov, Velimir V.
2017-10-28
Hydrologic models are commonly over-smoothed relative to reality, owing to computational limitations and to the difficulty of obtaining accurate high-resolution information. When used in an inversion context, such models may introduce systematic biases which cannot be encapsulated by an unbiased “observation noise” term of the type assumed by standard regularization theory and typical Bayesian formulations. Despite its importance, model error is difficult to encapsulate systematically and is often neglected. In this paper, model error is considered for an important class of inverse problems that includes interpretation of hydraulic transients and contaminant source history inference: reconstruction of a time series thatmore » has been convolved against a transfer function (i.e., impulse response) that is only approximately known. Using established harmonic theory along with two results established here regarding triangular Toeplitz matrices, upper and lower error bounds are derived for the effect of systematic model error on time series recovery for both well-determined and over-determined inverse problems. It is seen that use of additional measurement locations does not improve expected performance in the face of model error. A Monte Carlo study of a realistic hydraulic reconstruction problem is presented, and the lower error bound is seen informative about expected behavior. Finally, a possible diagnostic criterion for blind transfer function characterization is also uncovered.« less
Systematic Biases in Parameter Estimation of Binary Black-Hole Mergers
NASA Technical Reports Server (NTRS)
Littenberg, Tyson B.; Baker, John G.; Buonanno, Alessandra; Kelly, Bernard J.
2012-01-01
Parameter estimation of binary-black-hole merger events in gravitational-wave data relies on matched filtering techniques, which, in turn, depend on accurate model waveforms. Here we characterize the systematic biases introduced in measuring astrophysical parameters of binary black holes by applying the currently most accurate effective-one-body templates to simulated data containing non-spinning numerical-relativity waveforms. For advanced ground-based detectors, we find that the systematic biases are well within the statistical error for realistic signal-to-noise ratios (SNR). These biases grow to be comparable to the statistical errors at high signal-to-noise ratios for ground-based instruments (SNR approximately 50) but never dominate the error budget. At the much larger signal-to-noise ratios expected for space-based detectors, these biases will become large compared to the statistical errors but are small enough (at most a few percent in the black-hole masses) that we expect they should not affect broad astrophysical conclusions that may be drawn from the data.
Evaluation of normalization methods for cDNA microarray data by k-NN classification
Wu, Wei; Xing, Eric P; Myers, Connie; Mian, I Saira; Bissell, Mina J
2005-01-01
Background Non-biological factors give rise to unwanted variations in cDNA microarray data. There are many normalization methods designed to remove such variations. However, to date there have been few published systematic evaluations of these techniques for removing variations arising from dye biases in the context of downstream, higher-order analytical tasks such as classification. Results Ten location normalization methods that adjust spatial- and/or intensity-dependent dye biases, and three scale methods that adjust scale differences were applied, individually and in combination, to five distinct, published, cancer biology-related cDNA microarray data sets. Leave-one-out cross-validation (LOOCV) classification error was employed as the quantitative end-point for assessing the effectiveness of a normalization method. In particular, a known classifier, k-nearest neighbor (k-NN), was estimated from data normalized using a given technique, and the LOOCV error rate of the ensuing model was computed. We found that k-NN classifiers are sensitive to dye biases in the data. Using NONRM and GMEDIAN as baseline methods, our results show that single-bias-removal techniques which remove either spatial-dependent dye bias (referred later as spatial effect) or intensity-dependent dye bias (referred later as intensity effect) moderately reduce LOOCV classification errors; whereas double-bias-removal techniques which remove both spatial- and intensity effect reduce LOOCV classification errors even further. Of the 41 different strategies examined, three two-step processes, IGLOESS-SLFILTERW7, ISTSPLINE-SLLOESS and IGLOESS-SLLOESS, all of which removed intensity effect globally and spatial effect locally, appear to reduce LOOCV classification errors most consistently and effectively across all data sets. We also found that the investigated scale normalization methods do not reduce LOOCV classification error. Conclusion Using LOOCV error of k-NNs as the evaluation criterion, three double-bias-removal normalization strategies, IGLOESS-SLFILTERW7, ISTSPLINE-SLLOESS and IGLOESS-SLLOESS, outperform other strategies for removing spatial effect, intensity effect and scale differences from cDNA microarray data. The apparent sensitivity of k-NN LOOCV classification error to dye biases suggests that this criterion provides an informative measure for evaluating normalization methods. All the computational tools used in this study were implemented using the R language for statistical computing and graphics. PMID:16045803
Evaluation of normalization methods for cDNA microarray data by k-NN classification.
Wu, Wei; Xing, Eric P; Myers, Connie; Mian, I Saira; Bissell, Mina J
2005-07-26
Non-biological factors give rise to unwanted variations in cDNA microarray data. There are many normalization methods designed to remove such variations. However, to date there have been few published systematic evaluations of these techniques for removing variations arising from dye biases in the context of downstream, higher-order analytical tasks such as classification. Ten location normalization methods that adjust spatial- and/or intensity-dependent dye biases, and three scale methods that adjust scale differences were applied, individually and in combination, to five distinct, published, cancer biology-related cDNA microarray data sets. Leave-one-out cross-validation (LOOCV) classification error was employed as the quantitative end-point for assessing the effectiveness of a normalization method. In particular, a known classifier, k-nearest neighbor (k-NN), was estimated from data normalized using a given technique, and the LOOCV error rate of the ensuing model was computed. We found that k-NN classifiers are sensitive to dye biases in the data. Using NONRM and GMEDIAN as baseline methods, our results show that single-bias-removal techniques which remove either spatial-dependent dye bias (referred later as spatial effect) or intensity-dependent dye bias (referred later as intensity effect) moderately reduce LOOCV classification errors; whereas double-bias-removal techniques which remove both spatial- and intensity effect reduce LOOCV classification errors even further. Of the 41 different strategies examined, three two-step processes, IGLOESS-SLFILTERW7, ISTSPLINE-SLLOESS and IGLOESS-SLLOESS, all of which removed intensity effect globally and spatial effect locally, appear to reduce LOOCV classification errors most consistently and effectively across all data sets. We also found that the investigated scale normalization methods do not reduce LOOCV classification error. Using LOOCV error of k-NNs as the evaluation criterion, three double-bias-removal normalization strategies, IGLOESS-SLFILTERW7, ISTSPLINE-SLLOESS and IGLOESS-SLLOESS, outperform other strategies for removing spatial effect, intensity effect and scale differences from cDNA microarray data. The apparent sensitivity of k-NN LOOCV classification error to dye biases suggests that this criterion provides an informative measure for evaluating normalization methods. All the computational tools used in this study were implemented using the R language for statistical computing and graphics.
System calibration method for Fourier ptychographic microscopy.
Pan, An; Zhang, Yan; Zhao, Tianyu; Wang, Zhaojun; Dan, Dan; Lei, Ming; Yao, Baoli
2017-09-01
Fourier ptychographic microscopy (FPM) is a recently proposed computational imaging technique with both high-resolution and wide field of view. In current FPM imaging platforms, systematic error sources come from aberrations, light-emitting diode (LED) intensity fluctuation, parameter imperfections, and noise, all of which may severely corrupt the reconstruction results with similar artifacts. Therefore, it would be unlikely to distinguish the dominating error from these degraded reconstructions without any preknowledge. In addition, systematic error is generally a mixture of various error sources in the real situation, and it cannot be separated due to their mutual restriction and conversion. To this end, we report a system calibration procedure, termed SC-FPM, to calibrate the mixed systematic errors simultaneously from an overall perspective, based on the simulated annealing algorithm, the LED intensity correction method, the nonlinear regression process, and the adaptive step-size strategy, which involves the evaluation of an error metric at each iteration step, followed by the re-estimation of accurate parameters. The performance achieved both in simulations and experiments demonstrates that the proposed method outperforms other state-of-the-art algorithms. The reported system calibration scheme improves the robustness of FPM, relaxes the experiment conditions, and does not require any preknowledge, which makes the FPM more pragmatic. (2017) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE).
NASA Astrophysics Data System (ADS)
Semenov, Z. V.; Labusov, V. A.
2017-11-01
Results of studying the errors of indirect monitoring by means of computer simulations are reported. The monitoring method is based on measuring spectra of reflection from additional monitoring substrates in a wide spectral range. Special software (Deposition Control Simulator) is developed, which allows one to estimate the influence of the monitoring system parameters (noise of the photodetector array, operating spectral range of the spectrometer and errors of its calibration in terms of wavelengths, drift of the radiation source intensity, and errors in the refractive index of deposited materials) on the random and systematic errors of deposited layer thickness measurements. The direct and inverse problems of multilayer coatings are solved using the OptiReOpt library. Curves of the random and systematic errors of measurements of the deposited layer thickness as functions of the layer thickness are presented for various values of the system parameters. Recommendations are given on using the indirect monitoring method for the purpose of reducing the layer thickness measurement error.
Aberration caused by the errors of alignment and adjustment in reflecting telescope
NASA Astrophysics Data System (ADS)
Tan, Hui-Song
The 2-mirror Cassegrain geometry has firmly become a standard tool for modern astronomical research. The alignment and adjustment of aplanatic (RC) Cassegrain telescope is therefore by far the most important aspect. The errors that arise in telescope through maladjustment are discussed and the aberrations are calculated for the 2.4 m telescope which will be mounted at Gaomeigu.
Creel, Scott; Spong, Goran; Sands, Jennifer L; Rotella, Jay; Zeigle, Janet; Joe, Lawrence; Murphy, Kerry M; Smith, Douglas
2003-07-01
Determining population sizes can be difficult, but is essential for conservation. By counting distinct microsatellite genotypes, DNA from noninvasive samples (hair, faeces) allows estimation of population size. Problems arise because genotypes from noninvasive samples are error-prone, but genotyping errors can be reduced by multiple polymerase chain reaction (PCR). For faecal genotypes from wolves in Yellowstone National Park, error rates varied substantially among samples, often above the 'worst-case threshold' suggested by simulation. Consequently, a substantial proportion of multilocus genotypes held one or more errors, despite multiple PCR. These genotyping errors created several genotypes per individual and caused overestimation (up to 5.5-fold) of population size. We propose a 'matching approach' to eliminate this overestimation bias.
Stereoscopic distance perception
NASA Technical Reports Server (NTRS)
Foley, John M.
1989-01-01
Limited cue, open-loop tasks in which a human observer indicates distances or relations among distances are discussed. By open-loop tasks, it is meant tasks in which the observer gets no feedback as to the accuracy of the responses. What happens when cues are added and when the loop is closed are considered. The implications of this research for the effectiveness of visual displays is discussed. Errors in visual distance tasks do not necessarily mean that the percept is in error. The error could arise in transformations that intervene between the percept and the response. It is argued that the percept is in error. It is also argued that there exist post-perceptual transformations that may contribute to the error or be modified by feedback to correct for the error.
Vrijheid, Martine; Deltour, Isabelle; Krewski, Daniel; Sanchez, Marie; Cardis, Elisabeth
2006-07-01
This paper examines the effects of systematic and random errors in recall and of selection bias in case-control studies of mobile phone use and cancer. These sensitivity analyses are based on Monte-Carlo computer simulations and were carried out within the INTERPHONE Study, an international collaborative case-control study in 13 countries. Recall error scenarios simulated plausible values of random and systematic, non-differential and differential recall errors in amount of mobile phone use reported by study subjects. Plausible values for the recall error were obtained from validation studies. Selection bias scenarios assumed varying selection probabilities for cases and controls, mobile phone users, and non-users. Where possible these selection probabilities were based on existing information from non-respondents in INTERPHONE. Simulations used exposure distributions based on existing INTERPHONE data and assumed varying levels of the true risk of brain cancer related to mobile phone use. Results suggest that random recall errors of plausible levels can lead to a large underestimation in the risk of brain cancer associated with mobile phone use. Random errors were found to have larger impact than plausible systematic errors. Differential errors in recall had very little additional impact in the presence of large random errors. Selection bias resulting from underselection of unexposed controls led to J-shaped exposure-response patterns, with risk apparently decreasing at low to moderate exposure levels. The present results, in conjunction with those of the validation studies conducted within the INTERPHONE study, will play an important role in the interpretation of existing and future case-control studies of mobile phone use and cancer risk, including the INTERPHONE study.
Analyzing False Positives of Four Questions in the Force Concept Inventory
ERIC Educational Resources Information Center
Yasuda, Jun-ichro; Mae, Naohiro; Hull, Michael M.; Taniguchi, Masa-aki
2018-01-01
In this study, we analyze the systematic error from false positives of the Force Concept Inventory (FCI). We compare the systematic errors of question 6 (Q.6), Q.7, and Q.16, for which clearly erroneous reasoning has been found, with Q.5, for which clearly erroneous reasoning has not been found. We determine whether or not a correct response to a…
McDonald, Gene D; Storrie-Lombardi, Michael C
2006-02-01
The relative abundance of the protein amino acids has been previously investigated as a potential marker for biogenicity in meteoritic samples. However, these investigations were executed without a quantitative metric to evaluate distribution variations, and they did not account for the possibility of interdisciplinary systematic error arising from inter-laboratory differences in extraction and detection techniques. Principal component analysis (PCA), hierarchical cluster analysis (HCA), and stochastic probabilistic artificial neural networks (ANNs) were used to compare the distributions for nine protein amino acids previously reported for the Murchison carbonaceous chondrite, Mars meteorites (ALH84001, Nakhla, and EETA79001), prebiotic synthesis experiments, and terrestrial biota and sediments. These techniques allowed us (1) to identify a shift in terrestrial amino acid distributions secondary to diagenesis; (2) to detect differences in terrestrial distributions that may be systematic differences between extraction and analysis techniques in biological and geological laboratories; and (3) to determine that distributions in meteoritic samples appear more similar to prebiotic chemistry samples than they do to the terrestrial unaltered or diagenetic samples. Both diagenesis and putative interdisciplinary differences in analysis complicate interpretation of meteoritic amino acid distributions. We propose that the analysis of future samples from such diverse sources as meteoritic influx, sample return missions, and in situ exploration of Mars would be less ambiguous with adoption of standardized assay techniques, systematic inclusion of assay standards, and the use of a quantitative, probabilistic metric. We present here one such metric determined by sequential feature extraction and normalization (PCA), information-driven automated exploration of classification possibilities (HCA), and prediction of classification accuracy (ANNs).
Error Sources in Asteroid Astrometry
NASA Technical Reports Server (NTRS)
Owen, William M., Jr.
2000-01-01
Asteroid astrometry, like any other scientific measurement process, is subject to both random and systematic errors, not all of which are under the observer's control. To design an astrometric observing program or to improve an existing one requires knowledge of the various sources of error, how different errors affect one's results, and how various errors may be minimized by careful observation or data reduction techniques.
The Accuracy of GBM GRB Localizations
NASA Astrophysics Data System (ADS)
Briggs, Michael Stephen; Connaughton, V.; Meegan, C.; Hurley, K.
2010-03-01
We report an study of the accuracy of GBM GRB localizations, analyzing three types of localizations: those produced automatically by the GBM Flight Software on board GBM, those produced automatically with ground software in near real time, and localizations produced with human guidance. The two types of automatic locations are distributed in near real-time via GCN Notices; the human-guided locations are distributed on timescale of many minutes or hours using GCN Circulars. This work uses a Bayesian analysis that models the distribution of the GBM total location error by comparing GBM locations to more accurate locations obtained with other instruments. Reference locations are obtained from Swift, Super-AGILE, the LAT, and with the IPN. We model the GBM total location errors as having systematic errors in addition to the statistical errors and use the Bayesian analysis to constrain the systematic errors.
Mathes, Tim; Klaßen, Pauline; Pieper, Dawid
2017-11-28
Our objective was to assess the frequency of data extraction errors and its potential impact on results in systematic reviews. Furthermore, we evaluated the effect of different extraction methods, reviewer characteristics and reviewer training on error rates and results. We performed a systematic review of methodological literature in PubMed, Cochrane methodological registry, and by manual searches (12/2016). Studies were selected by two reviewers independently. Data were extracted in standardized tables by one reviewer and verified by a second. The analysis included six studies; four studies on extraction error frequency, one study comparing different reviewer extraction methods and two studies comparing different reviewer characteristics. We did not find a study on reviewer training. There was a high rate of extraction errors (up to 50%). Errors often had an influence on effect estimates. Different data extraction methods and reviewer characteristics had moderate effect on extraction error rates and effect estimates. The evidence base for established standards of data extraction seems weak despite the high prevalence of extraction errors. More comparative studies are needed to get deeper insights into the influence of different extraction methods.
NASA Technical Reports Server (NTRS)
Harwit, M.
1977-01-01
Sources of noise and error correcting procedures characteristic of Hadamard transform optical systems were investigated. Reduction of spectral noise due to noise spikes in the data, the effect of random errors, the relative performance of Fourier and Hadamard transform spectrometers operated under identical detector-noise-limited conditions, and systematic means for dealing with mask defects are among the topics discussed. The distortion in Hadamard transform optical instruments caused by moving Masks, incorrect mask alignment, missing measurements, and diffraction is analyzed and techniques for reducing or eliminating this distortion are described.
NASA Astrophysics Data System (ADS)
Koo, A.; Clare, J. F.
2012-06-01
Analysis of CIPM international comparisons is increasingly being carried out using a model-based approach that leads naturally to a generalized least-squares (GLS) solution. While this method offers the advantages of being easier to audit and having general applicability to any form of comparison protocol, there is a lack of consensus over aspects of its implementation. Two significant results are presented that show the equivalence of three differing approaches discussed by or applied in comparisons run by Consultative Committees of the CIPM. Both results depend on a mathematical condition equivalent to the requirement that any two artefacts in the comparison are linked through a sequence of measurements of overlapping pairs of artefacts. The first result is that a GLS estimator excluding all sources of error common to all measurements of a participant is equal to the GLS estimator incorporating all sources of error, including those associated with any bias in the standards or procedures of the measuring laboratory. The second result identifies the component of uncertainty in the estimate of bias that arises from possible systematic effects in the participants' measurement standards and procedures. The expression so obtained is a generalization of an expression previously published for a one-artefact comparison with no inter-participant correlations, to one for a comparison comprising any number of repeat measurements of multiple artefacts and allowing for inter-laboratory correlations.
NASA Technical Reports Server (NTRS)
Gupta, Hoshin V.; Kling, Harald; Yilmaz, Koray K.; Martinez-Baquero, Guillermo F.
2009-01-01
The mean squared error (MSE) and the related normalization, the Nash-Sutcliffe efficiency (NSE), are the two criteria most widely used for calibration and evaluation of hydrological models with observed data. Here, we present a diagnostically interesting decomposition of NSE (and hence MSE), which facilitates analysis of the relative importance of its different components in the context of hydrological modelling, and show how model calibration problems can arise due to interactions among these components. The analysis is illustrated by calibrating a simple conceptual precipitation-runoff model to daily data for a number of Austrian basins having a broad range of hydro-meteorological characteristics. Evaluation of the results clearly demonstrates the problems that can be associated with any calibration based on the NSE (or MSE) criterion. While we propose and test an alternative criterion that can help to reduce model calibration problems, the primary purpose of this study is not to present an improved measure of model performance. Instead, we seek to show that there are systematic problems inherent with any optimization based on formulations related to the MSE. The analysis and results have implications to the manner in which we calibrate and evaluate environmental models; we discuss these and suggest possible ways forward that may move us towards an improved and diagnostically meaningful approach to model performance evaluation and identification.
Systematic reviews, systematic error and the acquisition of clinical knowledge
2010-01-01
Background Since its inception, evidence-based medicine and its application through systematic reviews, has been widely accepted. However, it has also been strongly criticised and resisted by some academic groups and clinicians. One of the main criticisms of evidence-based medicine is that it appears to claim to have unique access to absolute scientific truth and thus devalues and replaces other types of knowledge sources. Discussion The various types of clinical knowledge sources are categorised on the basis of Kant's categories of knowledge acquisition, as being either 'analytic' or 'synthetic'. It is shown that these categories do not act in opposition but rather, depend upon each other. The unity of analysis and synthesis in knowledge acquisition is demonstrated during the process of systematic reviewing of clinical trials. Systematic reviews constitute comprehensive synthesis of clinical knowledge but depend upon plausible, analytical hypothesis development for the trials reviewed. The dangers of systematic error regarding the internal validity of acquired knowledge are highlighted on the basis of empirical evidence. It has been shown that the systematic review process reduces systematic error, thus ensuring high internal validity. It is argued that this process does not exclude other types of knowledge sources. Instead, amongst these other types it functions as an integrated element during the acquisition of clinical knowledge. Conclusions The acquisition of clinical knowledge is based on interaction between analysis and synthesis. Systematic reviews provide the highest form of synthetic knowledge acquisition in terms of achieving internal validity of results. In that capacity it informs the analytic knowledge of the clinician but does not replace it. PMID:20537172
NASA Astrophysics Data System (ADS)
Baron, J.; Campbell, W. C.; DeMille, D.; Doyle, J. M.; Gabrielse, G.; Gurevich, Y. V.; Hess, P. W.; Hutzler, N. R.; Kirilov, E.; Kozyryev, I.; O'Leary, B. R.; Panda, C. D.; Parsons, M. F.; Spaun, B.; Vutha, A. C.; West, A. D.; West, E. P.; ACME Collaboration
2017-07-01
We recently set a new limit on the electric dipole moment of the electron (eEDM) (J Baron et al and ACME collaboration 2014 Science 343 269-272), which represented an order-of-magnitude improvement on the previous limit and placed more stringent constraints on many charge-parity-violating extensions to the standard model. In this paper we discuss the measurement in detail. The experimental method and associated apparatus are described, together with the techniques used to isolate the eEDM signal. In particular, we detail the way experimental switches were used to suppress effects that can mimic the signal of interest. The methods used to search for systematic errors, and models explaining observed systematic errors, are also described. We briefly discuss possible improvements to the experiment.
Miraldi Utz, Virginia
2017-01-01
Myopia is the most common eye disorder and major cause of visual impairment worldwide. As the incidence of myopia continues to rise, the need to further understand the complex roles of molecular and environmental factors controlling variation in refractive error is of increasing importance. Tkatchenko and colleagues applied a systematic approach using a combination of gene set enrichment analysis, genome-wide association studies, and functional analysis of a murine model to identify a myopia susceptibility gene, APLP2. Differential expression of refractive error was associated with time spent reading for those with low frequency variants in this gene. This provides support for the longstanding hypothesis of gene-environment interactions in refractive error development.
NASA Astrophysics Data System (ADS)
Güttler, I.
2012-04-01
Systematic errors in near-surface temperature (T2m), total cloud cover (CLD), shortwave albedo (ALB) and surface net longwave (SNL) and shortwave energy flux (SNS) are detected in simulations of RegCM on 50 km resolution over the European CORDEX domain when forced with ERA-Interim reanalysis. Simulated T2m is compared to CRU 3.0 and other variables to GEWEX-SRB 3.0 dataset. Most of systematic errors found in SNL and SNS are consistent with errors in T2m, CLD and ALB: they include prevailing negative errors in T2m and positive errors in CLD present during most of the year. Errors in T2m and CLD can be associated with the overestimation of SNL and SNS in most simulations. Impact of errors in albedo are primarily confined to north Africa, where e.g. underestimation of albedo in JJA is consistent with associated surface heating and positive SNS and T2m errors. Sensitivity to the choice of the PBL scheme and various parameters in PBL schemes is examined from an ensemble of 20 simulations. The recently implemented prognostic PBL scheme performs over Europe with a mixed success when compared to standard diagnostic scheme with a general increase of errors in T2m and CLD over all of the domain. Nevertheless, the improvements in T2m can be found in e.g. north-eastern Europe during DJF and western Europe during JJA where substantial warm biases existed in simulations with the diagnostic scheme. The most detectable impact, in terms of the JJA T2m errors over western Europe, comes form the variation in the formulation of mixing length. In order to reduce the above errors an update of the RegCM albedo values and further work in customizing PBL scheme is suggested.
Interventions to reduce medication errors in neonatal care: a systematic review
Nguyen, Minh-Nha Rhylie; Mosel, Cassandra
2017-01-01
Background: Medication errors represent a significant but often preventable cause of morbidity and mortality in neonates. The objective of this systematic review was to determine the effectiveness of interventions to reduce neonatal medication errors. Methods: A systematic review was undertaken of all comparative and noncomparative studies published in any language, identified from searches of PubMed and EMBASE and reference-list checking. Eligible studies were those investigating the impact of any medication safety interventions aimed at reducing medication errors in neonates in the hospital setting. Results: A total of 102 studies were identified that met the inclusion criteria, including 86 comparative and 16 noncomparative studies. Medication safety interventions were classified into six themes: technology (n = 38; e.g. electronic prescribing), organizational (n = 16; e.g. guidelines, policies, and procedures), personnel (n = 13; e.g. staff education), pharmacy (n = 9; e.g. clinical pharmacy service), hazard and risk analysis (n = 8; e.g. error detection tools), and multifactorial (n = 18; e.g. any combination of previous interventions). Significant variability was evident across all included studies, with differences in intervention strategies, trial methods, types of medication errors evaluated, and how medication errors were identified and evaluated. Most studies demonstrated an appreciable risk of bias. The vast majority of studies (>90%) demonstrated a reduction in medication errors. A similar median reduction of 50–70% in medication errors was evident across studies included within each of the identified themes, but findings varied considerably from a 16% increase in medication errors to a 100% reduction in medication errors. Conclusion: While neonatal medication errors can be reduced through multiple interventions aimed at improving the medication use process, no single intervention appeared clearly superior. Further research is required to evaluate the relative cost-effectiveness of the various medication safety interventions to facilitate decisions regarding uptake and implementation into clinical practice. PMID:29387337
Distinctions between fraud, bias, errors, misunderstanding, and incompetence.
DeMets, D L
1997-12-01
Randomized clinical trials are challenging not only in their design and analysis, but in their conduct as well. Despite the best intentions and efforts, problems often arise in the conduct of trials, including errors, misunderstandings, and bias. In some instances, key players in a trial may discover that they are not able or competent to meet requirements of the study. In a few cases, fraudulent activity occurs. While none of these problems is desirable, randomized clinical trials are usually found sufficiently robust by many key individuals to produce valid results. Other problems are not tolerable. Confusion may arise among scientists, scientific and lay press, and the public about the distinctions between these areas and their implications. We shall try to define these problems and illustrate their impact through a series of examples.
Empirical Analysis of Systematic Communication Errors.
1981-09-01
human o~ . .... 8 components in communication systems. (Systematic errors were defined to be those that occur regularly in human communication links...phase of the human communication process and focuses on the linkage between a specific piece of information (and the receiver) and the transmission...communication flow. (2) Exchange. Exchange is the next phase in human communication and entails a concerted effort on the part of the sender and receiver to share
Systematics errors in strong lens modeling
NASA Astrophysics Data System (ADS)
Johnson, Traci L.; Sharon, Keren; Bayliss, Matthew B.
We investigate how varying the number of multiple image constraints and the available redshift information can influence the systematic errors of strong lens models, specifically, the image predictability, mass distribution, and magnifications of background sources. This work will not only inform upon Frontier Field science, but also for work on the growing collection of strong lensing galaxy clusters, most of which are less massive and are capable of lensing a handful of galaxies.
Low-Energy Proton Testing Methodology
NASA Technical Reports Server (NTRS)
Pellish, Jonathan A.; Marshall, Paul W.; Heidel, David F.; Schwank, James R.; Shaneyfelt, Marty R.; Xapsos, M.A.; Ladbury, Raymond L.; LaBel, Kenneth A.; Berg, Melanie; Kim, Hak S.;
2009-01-01
Use of low-energy protons and high-energy light ions is becoming necessary to investigate current-generation SEU thresholds. Systematic errors can dominate measurements made with low-energy protons. Range and energy straggling contribute to systematic error. Low-energy proton testing is not a step-and-repeat process. Low-energy protons and high-energy light ions can be used to measure SEU cross section of single sensitive features; important for simulation.
Accuracy of Jump-Mat Systems for Measuring Jump Height.
Pueo, Basilio; Lipinska, Patrycja; Jiménez-Olmedo, José M; Zmijewski, Piotr; Hopkins, Will G
2017-08-01
Vertical-jump tests are commonly used to evaluate lower-limb power of athletes and nonathletes. Several types of equipment are available for this purpose. To compare the error of measurement of 2 jump-mat systems (Chronojump-Boscosystem and Globus Ergo Tester) with that of a motion-capture system as a criterion and to determine the modifying effect of foot length on jump height. Thirty-one young adult men alternated 4 countermovement jumps with 4 squat jumps. Mean jump height and standard deviations representing technical error of measurement arising from each device and variability arising from the subjects themselves were estimated with a novel mixed model and evaluated via standardization and magnitude-based inference. The jump-mat systems produced nearly identical measures of jump height (differences in means and in technical errors of measurement ≤1 mm). Countermovement and squat-jump height were both 13.6 cm higher with motion capture (90% confidence limits ±0.3 cm), but this very large difference was reduced to small unclear differences when adjusted to a foot length of zero. Variability in countermovement and squat-jump height arising from the subjects was small (1.1 and 1.5 cm, respectively, 90% confidence limits ±0.3 cm); technical error of motion capture was similar in magnitude (1.7 and 1.6 cm, ±0.3 and ±0.4 cm), and that of the jump mats was similar or smaller (1.2 and 0.3 cm, ±0.5 and ±0.9 cm). The jump-mat systems provide trustworthy measurements for monitoring changes in jump height. Foot length can explain the substantially higher jump height observed with motion capture.
Performance of optimum detector structures for noisy intersymbol interference channels
NASA Technical Reports Server (NTRS)
Womer, J. D.; Fritchman, B. D.; Kanal, L. N.
1971-01-01
The errors which arise in transmitting digital information by radio or wireline systems because of additive noise from successively transmitted signals interfering with one another are described. The probability of error and the performance of optimum detector structures are examined. A comparative study of the performance of certain detector structures and approximations to them, and the performance of a transversal equalizer are included.
On the Probability of Error and Stochastic Resonance in Discrete Memoryless Channels
2013-12-01
Information - Driven Doppler Shift Estimation and Compensation Methods for Underwater Wireless Sensor Networks ”, which is to analyze and develop... underwater wireless sensor networks . We formulated an analytic relationship that relates the average probability of error to the systems parameters, the...thesis, we studied the performance of Discrete Memoryless Channels (DMC), arising in the context of cooperative underwater wireless sensor networks
Accurate Magnetometer/Gyroscope Attitudes Using a Filter with Correlated Sensor Noise
NASA Technical Reports Server (NTRS)
Sedlak, J.; Hashmall, J.
1997-01-01
Magnetometers and gyroscopes have been shown to provide very accurate attitudes for a variety of spacecraft. These results have been obtained, however, using a batch-least-squares algorithm and long periods of data. For use in onboard applications, attitudes are best determined using sequential estimators such as the Kalman filter. When a filter is used to determine attitudes using magnetometer and gyroscope data for input, the resulting accuracy is limited by both the sensor accuracies and errors inherent in the Earth magnetic field model. The Kalman filter accounts for the random component by modeling the magnetometer and gyroscope errors as white noise processes. However, even when these tuning parameters are physically realistic, the rate biases (included in the state vector) have been found to show systematic oscillations. These are attributed to the field model errors. If the gyroscope noise is sufficiently small, the tuned filter 'memory' will be long compared to the orbital period. In this case, the variations in the rate bias induced by field model errors are substantially reduced. Mistuning the filter to have a short memory time leads to strongly oscillating rate biases and increased attitude errors. To reduce the effect of the magnetic field model errors, these errors are estimated within the filter and used to correct the reference model. An exponentially-correlated noise model is used to represent the filter estimate of the systematic error. Results from several test cases using in-flight data from the Compton Gamma Ray Observatory are presented. These tests emphasize magnetometer errors, but the method is generally applicable to any sensor subject to a combination of random and systematic noise.
The Effects of Bar-coding Technology on Medication Errors: A Systematic Literature Review.
Hutton, Kevin; Ding, Qian; Wellman, Gregory
2017-02-24
The bar-coding technology adoptions have risen drastically in U.S. health systems in the past decade. However, few studies have addressed the impact of bar-coding technology with strong prospective methodologies and the research, which has been conducted from both in-pharmacy and bedside implementations. This systematic literature review is to examine the effectiveness of bar-coding technology on preventing medication errors and what types of medication errors may be prevented in the hospital setting. A systematic search of databases was performed from 1998 to December 2016. Studies measuring the effect of bar-coding technology on medication errors were included in a full-text review. Studies with the outcomes other than medication errors such as efficiency or workarounds were excluded. The outcomes were measured and findings were summarized for each retained study. A total of 2603 articles were initially identified and 10 studies, which used prospective before-and-after study design, were fully reviewed in this article. Of the 10 included studies, 9 took place in the United States, whereas the remaining was conducted in the United Kingdom. One research article focused on bar-coding implementation in a pharmacy setting, whereas the other 9 focused on bar coding within patient care areas. All 10 studies showed overall positive effects associated with bar-coding implementation. The results of this review show that bar-coding technology may reduce medication errors in hospital settings, particularly on preventing targeted wrong dose, wrong drug, wrong patient, unauthorized drug, and wrong route errors.
NASA Technical Reports Server (NTRS)
Martin, D. L.; Perry, M. J.
1994-01-01
Water-leaving radiances and phytoplankton pigment concentrations are calculated from coastal zone color scanner (CZCS) radiance measurements by removing atmospheric Rayleigh and aerosol radiances from the total radiance signal measured at the satellite. The single greatest source of error in CZCS atmospheric correction algorithms in the assumption that these Rayleigh and aerosol radiances are separable. Multiple-scattering interactions between Rayleigh and aerosol components cause systematic errors in calculated aerosol radiances, and the magnitude of these errors is dependent on aerosol type and optical depth and on satellite viewing geometry. A technique was developed which extends the results of previous radiative transfer modeling by Gordon and Castano to predict the magnitude of these systematic errors for simulated CZCS orbital passes in which the ocean is viewed through a modeled, physically realistic atmosphere. The simulated image mathematically duplicates the exact satellite, Sun, and pixel locations of an actual CZCS image. Errors in the aerosol radiance at 443 nm are calculated for a range of aerosol optical depths. When pixels in the simulated image exceed an error threshhold, the corresponding pixels in the actual CZCS image are flagged and excluded from further analysis or from use in image compositing or compilation of pigment concentration databases. Studies based on time series analyses or compositing of CZCS imagery which do not address Rayleigh-aerosol multiple scattering should be interpreted cautiously, since the fundamental assumption used in their atmospheric correction algorithm is flawed.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Shirasaki, Masato; Yoshida, Naoki, E-mail: masato.shirasaki@utap.phys.s.u-tokyo.ac.jp
2014-05-01
The measurement of cosmic shear using weak gravitational lensing is a challenging task that involves a number of complicated procedures. We study in detail the systematic errors in the measurement of weak-lensing Minkowski Functionals (MFs). Specifically, we focus on systematics associated with galaxy shape measurements, photometric redshift errors, and shear calibration correction. We first generate mock weak-lensing catalogs that directly incorporate the actual observational characteristics of the Canada-France-Hawaii Lensing Survey (CFHTLenS). We then perform a Fisher analysis using the large set of mock catalogs for various cosmological models. We find that the statistical error associated with the observational effects degradesmore » the cosmological parameter constraints by a factor of a few. The Subaru Hyper Suprime-Cam (HSC) survey with a sky coverage of ∼1400 deg{sup 2} will constrain the dark energy equation of the state parameter with an error of Δw {sub 0} ∼ 0.25 by the lensing MFs alone, but biases induced by the systematics can be comparable to the 1σ error. We conclude that the lensing MFs are powerful statistics beyond the two-point statistics only if well-calibrated measurement of both the redshifts and the shapes of source galaxies is performed. Finally, we analyze the CFHTLenS data to explore the ability of the MFs to break degeneracies between a few cosmological parameters. Using a combined analysis of the MFs and the shear correlation function, we derive the matter density Ω{sub m0}=0.256±{sub 0.046}{sup 0.054}.« less
NASA Technical Reports Server (NTRS)
Prive, Nikki C.; Errico, Ronald M.
2013-01-01
A series of experiments that explore the roles of model and initial condition error in numerical weather prediction are performed using an observing system simulation experiment (OSSE) framework developed at the National Aeronautics and Space Administration Global Modeling and Assimilation Office (NASA/GMAO). The use of an OSSE allows the analysis and forecast errors to be explicitly calculated, and different hypothetical observing networks can be tested with ease. In these experiments, both a full global OSSE framework and an 'identical twin' OSSE setup are utilized to compare the behavior of the data assimilation system and evolution of forecast skill with and without model error. The initial condition error is manipulated by varying the distribution and quality of the observing network and the magnitude of observation errors. The results show that model error has a strong impact on both the quality of the analysis field and the evolution of forecast skill, including both systematic and unsystematic model error components. With a realistic observing network, the analysis state retains a significant quantity of error due to systematic model error. If errors of the analysis state are minimized, model error acts to rapidly degrade forecast skill during the first 24-48 hours of forward integration. In the presence of model error, the impact of observation errors on forecast skill is small, but in the absence of model error, observation errors cause a substantial degradation of the skill of medium range forecasts.
A systematized WYSIWYG pipeline for digital stereoscopic 3D filmmaking
NASA Astrophysics Data System (ADS)
Mueller, Robert; Ward, Chris; Hušák, Michal
2008-02-01
Digital tools are transforming stereoscopic 3D content creation and delivery, creating an opportunity for the broad acceptance and success of stereoscopic 3D films. Beginning in late 2005, a series of mostly CGI features has successfully initiated the public to this new generation of highly-comfortable, artifact-free digital 3D. While the response has been decidedly favorable, a lack of high-quality live-action films could hinder long-term success. Liveaction stereoscopic films have historically been more time-consuming, costly, and creatively-limiting than 2D films - thus a need arises for a live-action 3D filmmaking process which minimizes such limitations. A unique 'systematized' what-you-see-is-what-you-get (WYSIWYG) pipeline is described which allows the efficient, intuitive and accurate capture and integration of 3D and 2D elements from multiple shoots and sources - both live-action and CGI. Throughout this pipeline, digital tools utilize a consistent algorithm to provide meaningful and accurate visual depth references with respect to the viewing audience in the target theater environment. This intuitive, visual approach introduces efficiency and creativity to the 3D filmmaking process by eliminating both the need for a 'mathematician mentality' of spreadsheets and calculators, as well as any trial and error guesswork, while enabling the most comfortable, 'pixel-perfect', artifact-free 3D product possible.
The first Fermi LAT supernova remnant catalog
Acero, F.
2016-05-16
To uniformly determine the properties of supernova remnants (SNRs) at high energies, we have developed the first systematic survey at energies from 1 to 100 GeV using data from the Fermi Large Area Telescope. Based on the spatial overlap of sources detected at GeV energies with SNRs known from radio surveys, we classify 30 sources as likely GeV SNRs. We also report 14 marginal associations and 245 flux upper limits. A mock catalog in which the positions of known remnants are scrambled in Galactic longitude, allows us to determine an upper limit of 22% on the number of GeV candidatesmore » falsely identified as SNRs. We have also developed a method to estimate spectral and spatial systematic errors arising from the diffuse interstellar emission model, a key component of all Galactic Fermi LAT analyses. By studying remnants uniformly in aggregate, we measure the GeV properties common to these objects and provide a crucial context for the detailed modeling of individual SNRs. Combining our GeV results with multiwavelength (MW) data, including radio, X-ray, and TeV, demonstrates the need for improvements to previously sufficient, simple models describing the GeV and radio emission from these objects. As a result, we model the GeV and MW emission from SNRs in aggregate to constrain their maximal contribution to observed Galactic cosmic rays.« less
THE FIRST FERMI LAT SUPERNOVA REMNANT CATALOG
DOE Office of Scientific and Technical Information (OSTI.GOV)
Acero, F.; Ballet, J.; Ackermann, M.
2016-05-01
To uniformly determine the properties of supernova remnants (SNRs) at high energies, we have developed the first systematic survey at energies from 1 to 100 GeV using data from the Fermi Large Area Telescope (LAT). Based on the spatial overlap of sources detected at GeV energies with SNRs known from radio surveys, we classify 30 sources as likely GeV SNRs. We also report 14 marginal associations and 245 flux upper limits. A mock catalog in which the positions of known remnants are scrambled in Galactic longitude allows us to determine an upper limit of 22% on the number of GeV candidates falsely identifiedmore » as SNRs. We have also developed a method to estimate spectral and spatial systematic errors arising from the diffuse interstellar emission model, a key component of all Galactic Fermi LAT analyses. By studying remnants uniformly in aggregate, we measure the GeV properties common to these objects and provide a crucial context for the detailed modeling of individual SNRs. Combining our GeV results with multiwavelength (MW) data, including radio, X-ray, and TeV, we demonstrate the need for improvements to previously sufficient, simple models describing the GeV and radio emission from these objects. We model the GeV and MW emission from SNRs in aggregate to constrain their maximal contribution to observed Galactic cosmic rays.« less
A-Posteriori Error Estimation for Hyperbolic Conservation Laws with Constraint
NASA Technical Reports Server (NTRS)
Barth, Timothy
2004-01-01
This lecture considers a-posteriori error estimates for the numerical solution of conservation laws with time invariant constraints such as those arising in magnetohydrodynamics (MHD) and gravitational physics. Using standard duality arguments, a-posteriori error estimates for the discontinuous Galerkin finite element method are then presented for MHD with solenoidal constraint. From these estimates, a procedure for adaptive discretization is outlined. A taxonomy of Green's functions for the linearized MHD operator is given which characterizes the domain of dependence for pointwise errors. The extension to other constrained systems such as the Einstein equations of gravitational physics are then considered. Finally, future directions and open problems are discussed.
An Analysis of Computational Errors in the Use of Division Algorithms by Fourth-Grade Students.
ERIC Educational Resources Information Center
Stefanich, Greg P.; Rokusek, Teri
1992-01-01
Presents a study that analyzed errors made by randomly chosen fourth grade students (25 of 57) while using the division algorithm and investigated the effect of remediation on identified systematic errors. Results affirm that error pattern diagnosis and directed remediation lead to new learning and long-term retention. (MDH)
Final Report: Correctness Tools for Petascale Computing
DOE Office of Scientific and Technical Information (OSTI.GOV)
Mellor-Crummey, John
2014-10-27
In the course of developing parallel programs for leadership computing systems, subtle programming errors often arise that are extremely difficult to diagnose without tools. To meet this challenge, University of Maryland, the University of Wisconsin—Madison, and Rice University worked to develop lightweight tools to help code developers pinpoint a variety of program correctness errors that plague parallel scientific codes. The aim of this project was to develop software tools that help diagnose program errors including memory leaks, memory access errors, round-off errors, and data races. Research at Rice University focused on developing algorithms and data structures to support efficient monitoringmore » of multithreaded programs for memory access errors and data races. This is a final report about research and development work at Rice University as part of this project.« less
de Cordova, Pamela B; Bradford, Michelle A; Stone, Patricia W
2016-02-15
Shift workers have worse health outcomes than employees who work standard business hours. However, it is unclear how this poorer health shift may be related to employee work productivity. The purpose of this systematic review is to assess the relationship between shift work and errors and performance. Searches of MEDLINE/PubMed, EBSCOhost, and CINAHL were conducted to identify articles that examined the relationship between shift work, errors, quality, productivity, and performance. All articles were assessed for study quality. A total of 435 abstracts were screened with 13 meeting inclusion criteria. Eight studies were rated to be of strong, methodological quality. Nine studies demonstrated a positive relationship that night shift workers committed more errors and had decreased performance. Night shift workers have worse health that may contribute to errors and decreased performance in the workplace.
NASA Technical Reports Server (NTRS)
Calhoun, Philip C.; Sedlak, Joseph E.; Superfin, Emil
2011-01-01
Precision attitude determination for recent and planned space missions typically includes quaternion star trackers (ST) and a three-axis inertial reference unit (IRU). Sensor selection is based on estimates of knowledge accuracy attainable from a Kalman filter (KF), which provides the optimal solution for the case of linear dynamics with measurement and process errors characterized by random Gaussian noise with white spectrum. Non-Gaussian systematic errors in quaternion STs are often quite large and have an unpredictable time-varying nature, particularly when used in non-inertial pointing applications. Two filtering methods are proposed to reduce the attitude estimation error resulting from ST systematic errors, 1) extended Kalman filter (EKF) augmented with Markov states, 2) Unscented Kalman filter (UKF) with a periodic measurement model. Realistic assessments of the attitude estimation performance gains are demonstrated with both simulation and flight telemetry data from the Lunar Reconnaissance Orbiter.
A water-vapor radiometer error model. [for ionosphere in geodetic microwave techniques
NASA Technical Reports Server (NTRS)
Beckman, B.
1985-01-01
The water-vapor radiometer (WVR) is used to calibrate unpredictable delays in the wet component of the troposphere in geodetic microwave techniques such as very-long-baseline interferometry (VLBI) and Global Positioning System (GPS) tracking. Based on experience with Jet Propulsion Laboratory (JPL) instruments, the current level of accuracy in wet-troposphere calibration limits the accuracy of local vertical measurements to 5-10 cm. The goal for the near future is 1-3 cm. Although the WVR is currently the best calibration method, many instruments are prone to systematic error. In this paper, a treatment of WVR data is proposed and evaluated. This treatment reduces the effect of WVR systematic errors by estimating parameters that specify an assumed functional form for the error. The assumed form of the treatment is evaluated by comparing the results of two similar WVR's operating near each other. Finally, the observability of the error parameters is estimated by covariance analysis.
NASA Astrophysics Data System (ADS)
Taut, A.; Berger, L.; Drews, C.; Bower, J.; Keilbach, D.; Lee, M. A.; Moebius, E.; Wimmer-Schweingruber, R. F.
2017-12-01
Complementary to the direct neutral particle measurements performed by e.g. IBEX, the measurement of PickUp Ions (PUIs) constitutes a diagnostic tool to investigate the local interstellar medium. PUIs are former neutral particles that have been ionized in the inner heliosphere. Subsequently, they are picked up by the solar wind and its frozen-in magnetic field. Due to this process, a characteristic Velocity Distribution Function (VDF) with a sharp cutoff evolves, which carries information about the PUI's injection speed and thus the former neutral particle velocity. The symmetry of the injection speed about the interstellar flow vector is used to derive the interstellar flow longitude from PUI measurements. Using He PUI data obtained by the PLASTIC sensor on STEREO A, we investigate how this concept may be affected by systematic errors. The PUI VDF strongly depends on the orientation of the local interplanetary magnetic field. Recently injected PUIs with speeds just below the cutoff speed typically form a highly anisotropic torus distribution in velocity space, which leads to a longitudinal transport for certain magnetic field orientation. Therefore, we investigate how the selection of magnetic field configurations in the data affects the result for the interstellar flow longitude that we derive from the PUI cutoff. Indeed, we find that the results follow a systematic trend with the filtered magnetic field angles that can lead to a shift of the result up to 5°. In turn, this means that every value for the interstellar flow longitude derived from the PUI cutoff is affected by a systematic error depending on the utilized magnetic field orientations. Here, we present our observations, discuss possible reasons for the systematic trend we discovered, and indicate selections that may minimize the systematic errors.
Closed medical negligence claims can drive patient safety and reduce litigation.
Pegalis, Steven E; Bal, B Sonny
2012-05-01
Medical liability reform is viewed by many physician groups as a means of reducing medical malpractice litigation and lowering healthcare costs. However, alternative approaches such as closed medical negligence claims data may also achieve these goals. We asked whether information gleaned from closed claims related to medical negligence could promote patient safety and reduce costs related to medical liability. Specifically, we investigated whether physician groups have examined such data to identify error patterns and to then institute specific patient treatment protocols. We searched for medical societies that have systematically examined closed medical negligence claims in their specialty to develop specific standards of physician conduct. We then searched the medical literature for published evidence of the efficacy, if any, related to the patient safety measures thus developed. Anesthesia and obstetric physician societies have successfully targeted costs and related concerns arising from medical malpractice lawsuits by using data from closed claims to develop patient safety and treatment guidelines. In both specialties, after institution of safety measures derived from closed medical negligence claims, the incidence and costs related to medical malpractice decreased and physician satisfaction improved. Tort reform, in the form of legislatively prescribed limits on damages arising from lawsuits, is not the only means of addressing the incidence and costs related to medical malpractice litigation. As the experience of anesthesia and obstetric physicians has demonstrated, safety guidelines derived from analyzing past medical malpractice litigation can achieve the same goals while also promoting patient safety.
Seismic Station Installation Orientation Errors at ANSS and IRIS/USGS Stations
Ringler, Adam T.; Hutt, Charles R.; Persfield, K.; Gee, Lind S.
2013-01-01
Many seismological studies depend on the published orientations of sensitive axes of seismic instruments relative to north (e.g., Li et al., 2011). For example, studies of the anisotropic structure of the Earth’s mantle through SKS‐splitting measurements (Long et al., 2009), constraints on core–mantle electromagnetic coupling from torsional normal‐mode measurements (Dumberry and Mound, 2008), and models of three‐dimensional (3D) velocity variations from surface waves (Ekström et al., 1997) rely on accurate sensor orientation. Unfortunately, numerous results indicate that this critical parameter is often subject to significant error (Laske, 1995; Laske and Masters, 1996; Yoshizawa et al., 1999; Schulte‐Pelkum et al., 2001; Larson and Ekström, 2002). For the Advanced National Seismic System (ANSS; ANSS Technical Integration Committee, 2002), the Global Seismographic Network (GSN; Butler et al., 2004), and many other networks, sensor orientation is typically determined by a field engineer during installation. Successful emplacement of a seismic instrument requires identifying true north, transferring a reference line, and measuring the orientation of the instrument relative to the reference line. Such an exercise is simple in theory, but there are many complications in practice. There are four commonly used methods for determining true north at the ANSS and GSN stations operated by the USGS Albuquerque Seismological Laboratory (ASL), including gyroscopic, astronomical, Global Positioning System (GPS), and magnetic field techniques. A particular method is selected based on site conditions (above ground, below ground, availability of astronomical observations, and so on) and in the case of gyroscopic methods, export restrictions. Once a north line has been determined, it must be translated to the sensor location. For installations in mines or deep vaults, this step can include tracking angles through the one or more turns in the access tunnel leading to the vault (e.g., GSN station WCI in Wyandotte Cave, Indiana). Finally, the third source of error comes from the ability of field engineers to orient the sensor relative to the reference line. In order to quantify bounds on the errors in each step in the orientation process, we conducted a series of tests at the ASL using twelve GSN and ANSS field engineers. The results from this exercise allow us to estimate upper bounds on the precision of our ability to orient instruments, as well as identify the sources of error in the procedures. We are also able to identify systematic bias of various true‐north‐finding methods relative to one another. Although we are unable to estimate the absolute accuracy of our orientation measurements due to our inability to identify true north without some error, the agreement between independent methods for finding true north provides confidence in the different approaches, assuming no systematic bias. Finally, our study neglects orientation errors that are beyond the control of the field engineer during a station visit. These additional errors can arise from deviations in the sensitive axes of the instruments relative to the case markings, processing errors (Holcomb, 2002) when comparing horizontal orientations relative to other sensors (e.g., borehole installations), and deviations of the sensitive axes of instruments from true orthogonality (e.g., instruments with separate modules such as the Streckeisen STS‐1).
A cognitive taxonomy of medical errors.
Zhang, Jiajie; Patel, Vimla L; Johnson, Todd R; Shortliffe, Edward H
2004-06-01
Propose a cognitive taxonomy of medical errors at the level of individuals and their interactions with technology. Use cognitive theories of human error and human action to develop the theoretical foundations of the taxonomy, develop the structure of the taxonomy, populate the taxonomy with examples of medical error cases, identify cognitive mechanisms for each category of medical error under the taxonomy, and apply the taxonomy to practical problems. Four criteria were used to evaluate the cognitive taxonomy. The taxonomy should be able (1) to categorize major types of errors at the individual level along cognitive dimensions, (2) to associate each type of error with a specific underlying cognitive mechanism, (3) to describe how and explain why a specific error occurs, and (4) to generate intervention strategies for each type of error. The proposed cognitive taxonomy largely satisfies the four criteria at a theoretical and conceptual level. Theoretically, the proposed cognitive taxonomy provides a method to systematically categorize medical errors at the individual level along cognitive dimensions, leads to a better understanding of the underlying cognitive mechanisms of medical errors, and provides a framework that can guide future studies on medical errors. Practically, it provides guidelines for the development of cognitive interventions to decrease medical errors and foundation for the development of medical error reporting system that not only categorizes errors but also identifies problems and helps to generate solutions. To validate this model empirically, we will next be performing systematic experimental studies.
Removal of batch effects using distribution-matching residual networks.
Shaham, Uri; Stanton, Kelly P; Zhao, Jun; Li, Huamin; Raddassi, Khadir; Montgomery, Ruth; Kluger, Yuval
2017-08-15
Sources of variability in experimentally derived data include measurement error in addition to the physical phenomena of interest. This measurement error is a combination of systematic components, originating from the measuring instrument and random measurement errors. Several novel biological technologies, such as mass cytometry and single-cell RNA-seq (scRNA-seq), are plagued with systematic errors that may severely affect statistical analysis if the data are not properly calibrated. We propose a novel deep learning approach for removing systematic batch effects. Our method is based on a residual neural network, trained to minimize the Maximum Mean Discrepancy between the multivariate distributions of two replicates, measured in different batches. We apply our method to mass cytometry and scRNA-seq datasets, and demonstrate that it effectively attenuates batch effects. our codes and data are publicly available at https://github.com/ushaham/BatchEffectRemoval.git. yuval.kluger@yale.edu. Supplementary data are available at Bioinformatics online. © The Author (2017). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com
Improved methods for the measurement and analysis of stellar magnetic fields
NASA Technical Reports Server (NTRS)
Saar, Steven H.
1988-01-01
The paper presents several improved methods for the measurement of magnetic fields on cool stars which take into account simple radiative transfer effects and the exact Zeeman patterns. Using these methods, high-resolution, low-noise data can be fitted with theoretical line profiles to determine the mean magnetic field strength in stellar active regions and a model-dependent fraction of the stellar surface (filling factor) covered by these regions. Random errors in the derived field strength and filling factor are parameterized in terms of signal-to-noise ratio, wavelength, spectral resolution, stellar rotation rate, and the magnetic parameters themselves. Weak line blends, if left uncorrected, can have significant systematic effects on the derived magnetic parameters, and thus several methods are developed to compensate partially for them. The magnetic parameters determined by previous methods likely have systematic errors because of such line blends and because of line saturation effects. Other sources of systematic error are explored in detail. These sources of error currently make it difficult to determine the magnetic parameters of individual stars to better than about + or - 20 percent.
Local blur analysis and phase error correction method for fringe projection profilometry systems.
Rao, Li; Da, Feipeng
2018-05-20
We introduce a flexible error correction method for fringe projection profilometry (FPP) systems in the presence of local blur phenomenon. Local blur caused by global light transport such as camera defocus, projector defocus, and subsurface scattering will cause significant systematic errors in FPP systems. Previous methods, which adopt high-frequency patterns to separate the direct and global components, fail when the global light phenomenon occurs locally. In this paper, the influence of local blur on phase quality is thoroughly analyzed, and a concise error correction method is proposed to compensate the phase errors. For defocus phenomenon, this method can be directly applied. With the aid of spatially varying point spread functions and local frontal plane assumption, experiments show that the proposed method can effectively alleviate the system errors and improve the final reconstruction accuracy in various scenes. For a subsurface scattering scenario, if the translucent object is dominated by multiple scattering, the proposed method can also be applied to correct systematic errors once the bidirectional scattering-surface reflectance distribution function of the object material is measured.
Dynamically corrected gates for singlet-triplet spin qubits with control-dependent errors
NASA Astrophysics Data System (ADS)
Jacobson, N. Tobias; Witzel, Wayne M.; Nielsen, Erik; Carroll, Malcolm S.
2013-03-01
Magnetic field inhomogeneity due to random polarization of quasi-static local magnetic impurities is a major source of environmentally induced error for singlet-triplet double quantum dot (DQD) spin qubits. Moreover, for singlet-triplet qubits this error may depend on the applied controls. This effect is significant when a static magnetic field gradient is applied to enable full qubit control. Through a configuration interaction analysis, we observe that the dependence of the field inhomogeneity-induced error on the DQD bias voltage can vary systematically as a function of the controls for certain experimentally relevant operating regimes. To account for this effect, we have developed a straightforward prescription for adapting dynamically corrected gate sequences that assume control-independent errors into sequences that compensate for systematic control-dependent errors. We show that accounting for such errors may lead to a substantial increase in gate fidelities. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. DOE's National Nuclear Security Administration under contract DE-AC04-94AL85000.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lee, Y; Fullerton, G; Goins, B
Purpose: In our previous study a preclinical multi-modality quality assurance (QA) phantom that contains five tumor-simulating test objects with 2, 4, 7, 10 and 14 mm diameters was developed for accurate tumor size measurement by researchers during cancer drug development and testing. This study analyzed the errors during tumor volume measurement from preclinical magnetic resonance (MR), micro-computed tomography (micro- CT) and ultrasound (US) images acquired in a rodent tumor model using the preclinical multi-modality QA phantom. Methods: Using preclinical 7-Tesla MR, US and micro-CT scanners, images were acquired of subcutaneous SCC4 tumor xenografts in nude rats (3–4 rats per group;more » 5 groups) along with the QA phantom using the same imaging protocols. After tumors were excised, in-air micro-CT imaging was performed to determine reference tumor volume. Volumes measured for the rat tumors and phantom test objects were calculated using formula V = (π/6)*a*b*c where a, b and c are the maximum diameters in three perpendicular dimensions determined by the three imaging modalities. Then linear regression analysis was performed to compare image-based tumor volumes with the reference tumor volume and known test object volume for the rats and the phantom respectively. Results: The slopes of regression lines for in-vivo tumor volumes measured by three imaging modalities were 1.021, 1.101 and 0.862 for MRI, micro-CT and US respectively. For phantom, the slopes were 0.9485, 0.9971 and 0.9734 for MRI, micro-CT and US respectively. Conclusion: For both animal and phantom studies, random and systematic errors were observed. Random errors were observer-dependent and systematic errors were mainly due to selected imaging protocols and/or measurement method. In the animal study, there were additional systematic errors attributed to ellipsoidal assumption for tumor shape. The systematic errors measured using the QA phantom need to be taken into account to reduce measurement errors during the animal study.« less
Atmospheric Dispersion Effects in Weak Lensing Measurements
Plazas, Andrés Alejandro; Bernstein, Gary
2012-10-01
The wavelength dependence of atmospheric refraction causes elongation of finite-bandwidth images along the elevation vector, which produces spurious signals in weak gravitational lensing shear measurements unless this atmospheric dispersion is calibrated and removed to high precision. Because astrometric solutions and PSF characteristics are typically calibrated from stellar images, differences between the reference stars' spectra and the galaxies' spectra will leave residual errors in both the astrometric positions (dr) and in the second moment (width) of the wavelength-averaged PSF (dv) for galaxies.We estimate the level of dv that will induce spurious weak lensing signals in PSF-corrected galaxy shapes that exceed themore » statistical errors of the DES and the LSST cosmic-shear experiments. We also estimate the dr signals that will produce unacceptable spurious distortions after stacking of exposures taken at different airmasses and hour angles. We also calculate the errors in the griz bands, and find that dispersion systematics, uncorrected, are up to 6 and 2 times larger in g and r bands,respectively, than the requirements for the DES error budget, but can be safely ignored in i and z bands. For the LSST requirements, the factors are about 30, 10, and 3 in g, r, and i bands,respectively. We find that a simple correction linear in galaxy color is accurate enough to reduce dispersion shear systematics to insignificant levels in the r band for DES and i band for LSST,but still as much as 5 times than the requirements for LSST r-band observations. More complex corrections will likely be able to reduce the systematic cosmic-shear errors below statistical errors for LSST r band. But g-band effects remain large enough that it seems likely that induced systematics will dominate the statistical errors of both surveys, and cosmic-shear measurements should rely on the redder bands.« less
Ground state properties of 3d metals from self-consistent GW approach
Kutepov, Andrey L.
2017-10-06
The self consistent GW approach (scGW) has been applied to calculate the ground state properties (equilibrium Wigner–Seitz radius S WZ and bulk modulus B) of 3d transition metals Sc, Ti, V, Fe, Co, Ni, and Cu. The approach systematically underestimates S WZ with average relative deviation from the experimental data of about 1% and it overestimates the calculated bulk modulus with relative error of about 25%. We show that scGW is superior in accuracy as compared to the local density approximation but it is less accurate than the generalized gradient approach for the materials studied. If compared to the randommore » phase approximation, scGW is slightly less accurate, but its error for 3d metals looks more systematic. Lastly, the systematic nature of the deviation from the experimental data suggests that the next order of the perturbation theory should allow one to reduce the error.« less
Ground state properties of 3d metals from self-consistent GW approach
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kutepov, Andrey L.
The self consistent GW approach (scGW) has been applied to calculate the ground state properties (equilibrium Wigner–Seitz radius S WZ and bulk modulus B) of 3d transition metals Sc, Ti, V, Fe, Co, Ni, and Cu. The approach systematically underestimates S WZ with average relative deviation from the experimental data of about 1% and it overestimates the calculated bulk modulus with relative error of about 25%. We show that scGW is superior in accuracy as compared to the local density approximation but it is less accurate than the generalized gradient approach for the materials studied. If compared to the randommore » phase approximation, scGW is slightly less accurate, but its error for 3d metals looks more systematic. Lastly, the systematic nature of the deviation from the experimental data suggests that the next order of the perturbation theory should allow one to reduce the error.« less
A systematic comparison of error correction enzymes by next-generation sequencing
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lubock, Nathan B.; Zhang, Di; Sidore, Angus M.
Gene synthesis, the process of assembling genelength fragments from shorter groups of oligonucleotides (oligos), is becoming an increasingly important tool in molecular and synthetic biology. The length, quality and cost of gene synthesis are limited by errors produced during oligo synthesis and subsequent assembly. Enzymatic error correction methods are cost-effective means to ameliorate errors in gene synthesis. Previous analyses of these methods relied on cloning and Sanger sequencing to evaluate their efficiencies, limiting quantitative assessment. Here, we develop a method to quantify errors in synthetic DNA by next-generation sequencing. We analyzed errors in model gene assemblies and systematically compared sixmore » different error correction enzymes across 11 conditions. We find that ErrASE and T7 Endonuclease I are the most effective at decreasing average error rates (up to 5.8-fold relative to the input), whereas MutS is the best for increasing the number of perfect assemblies (up to 25.2-fold). We are able to quantify differential specificities such as ErrASE preferentially corrects C/G transversions whereas T7 Endonuclease I preferentially corrects A/T transversions. More generally, this experimental and computational pipeline is a fast, scalable and extensible way to analyze errors in gene assemblies, to profile error correction methods, and to benchmark DNA synthesis methods.« less
A systematic comparison of error correction enzymes by next-generation sequencing
Lubock, Nathan B.; Zhang, Di; Sidore, Angus M.; ...
2017-08-01
Gene synthesis, the process of assembling genelength fragments from shorter groups of oligonucleotides (oligos), is becoming an increasingly important tool in molecular and synthetic biology. The length, quality and cost of gene synthesis are limited by errors produced during oligo synthesis and subsequent assembly. Enzymatic error correction methods are cost-effective means to ameliorate errors in gene synthesis. Previous analyses of these methods relied on cloning and Sanger sequencing to evaluate their efficiencies, limiting quantitative assessment. Here, we develop a method to quantify errors in synthetic DNA by next-generation sequencing. We analyzed errors in model gene assemblies and systematically compared sixmore » different error correction enzymes across 11 conditions. We find that ErrASE and T7 Endonuclease I are the most effective at decreasing average error rates (up to 5.8-fold relative to the input), whereas MutS is the best for increasing the number of perfect assemblies (up to 25.2-fold). We are able to quantify differential specificities such as ErrASE preferentially corrects C/G transversions whereas T7 Endonuclease I preferentially corrects A/T transversions. More generally, this experimental and computational pipeline is a fast, scalable and extensible way to analyze errors in gene assemblies, to profile error correction methods, and to benchmark DNA synthesis methods.« less
NASA Astrophysics Data System (ADS)
Fathalli, Bilel; Pohl, Benjamin; Castel, Thierry; Safi, Mohamed Jomâa
2018-02-01
Temporal and spatial variability of rainfall over Tunisia (at 12 km spatial resolution) is analyzed in a multi-year (1992-2011) ten-member ensemble simulation performed using the WRF model, and a sample of regional climate hindcast simulations from Euro-CORDEX. RCM errors and skills are evaluated against a dense network of local rain gauges. Uncertainties arising, on the one hand, from the different model configurations and, on the other hand, from internal variability are furthermore quantified and ranked at different timescales using simple spread metrics. Overall, the WRF simulation shows good skill for simulating spatial patterns of rainfall amounts over Tunisia, marked by strong altitudinal and latitudinal gradients, as well as the rainfall interannual variability, in spite of systematic errors. Mean rainfall biases are wet in both DJF and JJA seasons for the WRF ensemble, while they are dry in winter and wet in summer for most of the used Euro-CORDEX models. The sign of mean annual rainfall biases over Tunisia can also change from one member of the WRF ensemble to another. Skills in regionalizing precipitation over Tunisia are season dependent, with better correlations and weaker biases in winter. Larger inter-member spreads are observed in summer, likely because of (1) an attenuated large-scale control on Mediterranean and Tunisian climate, and (2) a larger contribution of local convective rainfall to the seasonal amounts. Inter-model uncertainties are globally stronger than those attributed to model's internal variability. However, inter-member spreads can be of the same magnitude in summer, emphasizing the important stochastic nature of the summertime rainfall variability over Tunisia.
NASA Technical Reports Server (NTRS)
Casper, Paul W.; Bent, Rodney B.
1991-01-01
The algorithm used in previous technology time-of-arrival lightning mapping systems was based on the assumption that the earth is a perfect spheroid. These systems yield highly-accurate lightning locations, which is their major strength. However, extensive analysis of tower strike data has revealed occasionally significant (one to two kilometer) systematic offset errors which are not explained by the usual error sources. It was determined that these systematic errors reduce dramatically (in some cases) when the oblate shape of the earth is taken into account. The oblate spheroid correction algorithm and a case example is presented.
Error reduction and parameter optimization of the TAPIR method for fast T1 mapping.
Zaitsev, M; Steinhoff, S; Shah, N J
2003-06-01
A methodology is presented for the reduction of both systematic and random errors in T(1) determination using TAPIR, a Look-Locker-based fast T(1) mapping technique. The relations between various sequence parameters were carefully investigated in order to develop recipes for choosing optimal sequence parameters. Theoretical predictions for the optimal flip angle were verified experimentally. Inversion pulse imperfections were identified as the main source of systematic errors in T(1) determination with TAPIR. An effective remedy is demonstrated which includes extension of the measurement protocol to include a special sequence for mapping the inversion efficiency itself. Copyright 2003 Wiley-Liss, Inc.
A Family of Algorithms for Computing Consensus about Node State from Network Data
Brush, Eleanor R.; Krakauer, David C.; Flack, Jessica C.
2013-01-01
Biological and social networks are composed of heterogeneous nodes that contribute differentially to network structure and function. A number of algorithms have been developed to measure this variation. These algorithms have proven useful for applications that require assigning scores to individual nodes–from ranking websites to determining critical species in ecosystems–yet the mechanistic basis for why they produce good rankings remains poorly understood. We show that a unifying property of these algorithms is that they quantify consensus in the network about a node's state or capacity to perform a function. The algorithms capture consensus by either taking into account the number of a target node's direct connections, and, when the edges are weighted, the uniformity of its weighted in-degree distribution (breadth), or by measuring net flow into a target node (depth). Using data from communication, social, and biological networks we find that that how an algorithm measures consensus–through breadth or depth– impacts its ability to correctly score nodes. We also observe variation in sensitivity to source biases in interaction/adjacency matrices: errors arising from systematic error at the node level or direct manipulation of network connectivity by nodes. Our results indicate that the breadth algorithms, which are derived from information theory, correctly score nodes (assessed using independent data) and are robust to errors. However, in cases where nodes “form opinions” about other nodes using indirect information, like reputation, depth algorithms, like Eigenvector Centrality, are required. One caveat is that Eigenvector Centrality is not robust to error unless the network is transitive or assortative. In these cases the network structure allows the depth algorithms to effectively capture breadth as well as depth. Finally, we discuss the algorithms' cognitive and computational demands. This is an important consideration in systems in which individuals use the collective opinions of others to make decisions. PMID:23874167
NASA Astrophysics Data System (ADS)
Zeqiri, Bajram; Cook, Ashley; Rétat, Lise; Civale, John; ter Haar, Gail
2015-04-01
The acoustic nonlinearity parameter, B/A, is an important parameter which defines the way a propagating finite amplitude acoustic wave progressively distorts when travelling through any medium. One measurement technique used to determine its value is the finite amplitude insertion substitution (FAIS) method which has been applied to a range of liquid, tissue and tissue-like media. Importantly, in terms of the achievable measurement uncertainties, it is a relative technique. This paper presents a detailed study of the method, employing a number of novel features. The first of these is the use of a large area membrane hydrophone (30 mm aperture) which is used to record the plane-wave component of the acoustic field. This reduces the influence of diffraction on measurements, enabling studies to be carried out within the transducer near-field, with the interrogating transducer, test cell and detector positioned close to one another, an attribute which assists in controlling errors arising from nonlinear distortion in any intervening water path. The second feature is the development of a model which estimates the influence of finite-amplitude distortion as the acoustic wave travels from the rear surface of the test cell to the detector. It is demonstrated that this can lead to a significant systematic error in B/A measurement whose magnitude and direction depends on the acoustic property contrast between the test material and the water-filled equivalent cell. Good qualitative agreement between the model and experiment is reported. B/A measurements are reported undertaken at (20 ± 0.5) °C for two fluids commonly employed as reference materials within the technical literature: Corn Oil and Ethylene Glycol. Samples of an IEC standardised agar-based tissue-mimicking material were also measured. A systematic assessment of measurement uncertainties is presented giving expanded uncertainties in the range ±7% to ±14%, expressed at a confidence level close to 95%, dependent on specimen details.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Nagler, Peter C.; Tucker, Gregory S.; Fixsen, Dale J.
The detection of the primordial B-mode polarization signal of the cosmic microwave background (CMB) would provide evidence for inflation. Yet as has become increasingly clear, the detection of a such a faint signal requires an instrument with both wide frequency coverage to reject foregrounds and excellent control over instrumental systematic effects. Using a polarizing Fourier transform spectrometer (FTS) for CMB observations meets both of these requirements. In this work, we present an analysis of instrumental systematic effects in polarizing FTSs, using the Primordial Inflation Explorer (PIXIE) as a worked example. We analytically solve for the most important systematic effects inherentmore » to the FTS—emissive optical components, misaligned optical components, sampling and phase errors, and spin synchronous effects—and demonstrate that residual systematic error terms after corrections will all be at the sub-nK level, well below the predicted 100 nK B-mode signal.« less
McGregor, Heather R.; Pun, Henry C. H.; Buckingham, Gavin; Gribble, Paul L.
2016-01-01
The human sensorimotor system is routinely capable of making accurate predictions about an object's weight, which allows for energetically efficient lifts and prevents objects from being dropped. Often, however, poor predictions arise when the weight of an object can vary and sensory cues about object weight are sparse (e.g., picking up an opaque water bottle). The question arises, what strategies does the sensorimotor system use to make weight predictions when one is dealing with an object whose weight may vary? For example, does the sensorimotor system use a strategy that minimizes prediction error (minimal squared error) or one that selects the weight that is most likely to be correct (maximum a posteriori)? In this study we dissociated the predictions of these two strategies by having participants lift an object whose weight varied according to a skewed probability distribution. We found, using a small range of weight uncertainty, that four indexes of sensorimotor prediction (grip force rate, grip force, load force rate, and load force) were consistent with a feedforward strategy that minimizes the square of prediction errors. These findings match research in the visuomotor system, suggesting parallels in underlying processes. We interpret our findings within a Bayesian framework and discuss the potential benefits of using a minimal squared error strategy. NEW & NOTEWORTHY Using a novel experimental model of object lifting, we tested whether the sensorimotor system models the weight of objects by minimizing lifting errors or by selecting the statistically most likely weight. We found that the sensorimotor system minimizes the square of prediction errors for object lifting. This parallels the results of studies that investigated visually guided reaching, suggesting an overlap in the underlying mechanisms between tasks that involve different sensory systems. PMID:27760821
Analysis of a hardware and software fault tolerant processor for critical applications
NASA Technical Reports Server (NTRS)
Dugan, Joanne B.
1993-01-01
Computer systems for critical applications must be designed to tolerate software faults as well as hardware faults. A unified approach to tolerating hardware and software faults is characterized by classifying faults in terms of duration (transient or permanent) rather than source (hardware or software). Errors arising from transient faults can be handled through masking or voting, but errors arising from permanent faults require system reconfiguration to bypass the failed component. Most errors which are caused by software faults can be considered transient, in that they are input-dependent. Software faults are triggered by a particular set of inputs. Quantitative dependability analysis of systems which exhibit a unified approach to fault tolerance can be performed by a hierarchical combination of fault tree and Markov models. A methodology for analyzing hardware and software fault tolerant systems is applied to the analysis of a hypothetical system, loosely based on the Fault Tolerant Parallel Processor. The models consider both transient and permanent faults, hardware and software faults, independent and related software faults, automatic recovery, and reconfiguration.
Kahrass, Hannes; Strech, Daniel; Mertz, Marcel
2016-01-01
When treating patients with kidney failure, unavoidable ethical issues often arise. Current clinical practice guidelines some of them, but lack comprehensive information about the full range of relevant ethical issues in kidney failure. A systematic literature review of such ethical issues supports medical professionalism in nephrology, and offers a solid evidential base for efforts that aim to improve ethical conduct in health care. To identify the full spectrum of clinical ethical issues that can arise for patients with kidney failure in a systematic and transparent manner. A systematic review in Medline (publications in English or German between 2000 and 2014) and Google Books (with no restrictions) was conducted. Ethical issues were identified by qualitative text analysis and normative analysis. The literature review retrieved 106 references that together mentioned 27 ethical issues in clinical care of kidney failure. This set of ethical issues was structured into a matrix consisting of seven major categories and further first and second-order categories. The systematically-derived matrix helps raise awareness and understanding of the complexity of ethical issues in kidney failure. It can be used to identify ethical issues that should be addressed in specific training programs for clinicians, clinical practice guidelines, or other types of policies dealing with kidney failure.
Kahrass, Hannes; Strech, Daniel; Mertz, Marcel
2016-01-01
Background When treating patients with kidney failure, unavoidable ethical issues often arise. Current clinical practice guidelines some of them, but lack comprehensive information about the full range of relevant ethical issues in kidney failure. A systematic literature review of such ethical issues supports medical professionalism in nephrology, and offers a solid evidential base for efforts that aim to improve ethical conduct in health care. Aim To identify the full spectrum of clinical ethical issues that can arise for patients with kidney failure in a systematic and transparent manner. Method A systematic review in Medline (publications in English or German between 2000 and 2014) and Google Books (with no restrictions) was conducted. Ethical issues were identified by qualitative text analysis and normative analysis. Results The literature review retrieved 106 references that together mentioned 27 ethical issues in clinical care of kidney failure. This set of ethical issues was structured into a matrix consisting of seven major categories and further first and second-order categories. Conclusions The systematically-derived matrix helps raise awareness and understanding of the complexity of ethical issues in kidney failure. It can be used to identify ethical issues that should be addressed in specific training programs for clinicians, clinical practice guidelines, or other types of policies dealing with kidney failure. PMID:26938863
Why GPS makes distances bigger than they are
Ranacher, Peter; Brunauer, Richard; Trutschnig, Wolfgang; Van der Spek, Stefan; Reich, Siegfried
2016-01-01
ABSTRACT Global navigation satellite systems such as the Global Positioning System (GPS) is one of the most important sensors for movement analysis. GPS is widely used to record the trajectories of vehicles, animals and human beings. However, all GPS movement data are affected by both measurement and interpolation errors. In this article we show that measurement error causes a systematic bias in distances recorded with a GPS; the distance between two points recorded with a GPS is – on average – bigger than the true distance between these points. This systematic ‘overestimation of distance’ becomes relevant if the influence of interpolation error can be neglected, which in practice is the case for movement sampled at high frequencies. We provide a mathematical explanation of this phenomenon and illustrate that it functionally depends on the autocorrelation of GPS measurement error (C). We argue that C can be interpreted as a quality measure for movement data recorded with a GPS. If there is a strong autocorrelation between any two consecutive position estimates, they have very similar error. This error cancels out when average speed, distance or direction is calculated along the trajectory. Based on our theoretical findings we introduce a novel approach to determine C in real-world GPS movement data sampled at high frequencies. We apply our approach to pedestrian trajectories and car trajectories. We found that the measurement error in the data was strongly spatially and temporally autocorrelated and give a quality estimate of the data. Most importantly, our findings are not limited to GPS alone. The systematic bias and its implications are bound to occur in any movement data collected with absolute positioning if interpolation error can be neglected. PMID:27019610
Marathe, A R; Taylor, D M
2015-08-01
Decoding algorithms for brain-machine interfacing (BMI) are typically only optimized to reduce the magnitude of decoding errors. Our goal was to systematically quantify how four characteristics of BMI command signals impact closed-loop performance: (1) error magnitude, (2) distribution of different frequency components in the decoding errors, (3) processing delays, and (4) command gain. To systematically evaluate these different command features and their interactions, we used a closed-loop BMI simulator where human subjects used their own wrist movements to command the motion of a cursor to targets on a computer screen. Random noise with three different power distributions and four different relative magnitudes was added to the ongoing cursor motion in real time to simulate imperfect decoding. These error characteristics were tested with four different visual feedback delays and two velocity gains. Participants had significantly more trouble correcting for errors with a larger proportion of low-frequency, slow-time-varying components than they did with jittery, higher-frequency errors, even when the error magnitudes were equivalent. When errors were present, a movement delay often increased the time needed to complete the movement by an order of magnitude more than the delay itself. Scaling down the overall speed of the velocity command can actually speed up target acquisition time when low-frequency errors and delays are present. This study is the first to systematically evaluate how the combination of these four key command signal features (including the relatively-unexplored error power distribution) and their interactions impact closed-loop performance independent of any specific decoding method. The equations we derive relating closed-loop movement performance to these command characteristics can provide guidance on how best to balance these different factors when designing BMI systems. The equations reported here also provide an efficient way to compare a diverse range of decoding options offline.
NASA Astrophysics Data System (ADS)
Marathe, A. R.; Taylor, D. M.
2015-08-01
Objective. Decoding algorithms for brain-machine interfacing (BMI) are typically only optimized to reduce the magnitude of decoding errors. Our goal was to systematically quantify how four characteristics of BMI command signals impact closed-loop performance: (1) error magnitude, (2) distribution of different frequency components in the decoding errors, (3) processing delays, and (4) command gain. Approach. To systematically evaluate these different command features and their interactions, we used a closed-loop BMI simulator where human subjects used their own wrist movements to command the motion of a cursor to targets on a computer screen. Random noise with three different power distributions and four different relative magnitudes was added to the ongoing cursor motion in real time to simulate imperfect decoding. These error characteristics were tested with four different visual feedback delays and two velocity gains. Main results. Participants had significantly more trouble correcting for errors with a larger proportion of low-frequency, slow-time-varying components than they did with jittery, higher-frequency errors, even when the error magnitudes were equivalent. When errors were present, a movement delay often increased the time needed to complete the movement by an order of magnitude more than the delay itself. Scaling down the overall speed of the velocity command can actually speed up target acquisition time when low-frequency errors and delays are present. Significance. This study is the first to systematically evaluate how the combination of these four key command signal features (including the relatively-unexplored error power distribution) and their interactions impact closed-loop performance independent of any specific decoding method. The equations we derive relating closed-loop movement performance to these command characteristics can provide guidance on how best to balance these different factors when designing BMI systems. The equations reported here also provide an efficient way to compare a diverse range of decoding options offline.
The Observational Determination of the Primordial Helium Abundance: a Y2K Status Report
NASA Astrophysics Data System (ADS)
Skillman, Evan D.
I review observational progress and assess the current state of the determination of the primordial helium abundance, Yp. At present there are two determinations with non-overlapping errors. My impression is that the errors have been under-estimated in both studies. I review recent work on errors assessment and give suggestions for decreasing systematic errors in future studies.
Improved Quality in Aerospace Testing Through the Modern Design of Experiments
NASA Technical Reports Server (NTRS)
DeLoach, R.
2000-01-01
This paper illustrates how, in the presence of systematic error, the quality of an experimental result can be influenced by the order in which the independent variables are set. It is suggested that in typical experimental circumstances in which systematic errors are significant, the common practice of organizing the set point order of independent variables to maximize data acquisition rate results in a test matrix that fails to produce the highest quality research result. With some care to match the volume of data required to satisfy inference error risk tolerances, it is possible to accept a lower rate of data acquisition and still produce results of higher technical quality (lower experimental error) with less cost and in less time than conventional test procedures, simply by optimizing the sequence in which independent variable levels are set.
Detecting Spatial Patterns in Biological Array Experiments
ROOT, DAVID E.; KELLEY, BRIAN P.; STOCKWELL, BRENT R.
2005-01-01
Chemical genetic screening and DNA and protein microarrays are among a number of increasingly important and widely used biological research tools that involve large numbers of parallel experiments arranged in a spatial array. It is often difficult to ensure that uniform experimental conditions are present throughout the entire array, and as a result, one often observes systematic spatially correlated errors, especially when array experiments are performed using robots. Here, the authors apply techniques based on the discrete Fourier transform to identify and quantify spatially correlated errors superimposed on a spatially random background. They demonstrate that these techniques are effective in identifying common spatially systematic errors in high-throughput 384-well microplate assay data. In addition, the authors employ a statistical test to allow for automatic detection of such errors. Software tools for using this approach are provided. PMID:14567791
Zhao, Qilong; Strykowski, Gabriel; Li, Jiancheng; Pan, Xiong; Xu, Xinyu
2017-05-25
Gravity data gaps in mountainous areas are nowadays often filled in with the data from airborne gravity surveys. Because of the errors caused by the airborne gravimeter sensors, and because of rough flight conditions, such errors cannot be completely eliminated. The precision of the gravity disturbances generated by the airborne gravimetry is around 3-5 mgal. A major obstacle in using airborne gravimetry are the errors caused by the downward continuation. In order to improve the results the external high-accuracy gravity information e.g., from the surface data can be used for high frequency correction, while satellite information can be applying for low frequency correction. Surface data may be used to reduce the systematic errors, while regularization methods can reduce the random errors in downward continuation. Airborne gravity surveys are sometimes conducted in mountainous areas and the most extreme area of the world for this type of survey is the Tibetan Plateau. Since there are no high-accuracy surface gravity data available for this area, the above error minimization method involving the external gravity data cannot be used. We propose a semi-parametric downward continuation method in combination with regularization to suppress the systematic error effect and the random error effect in the Tibetan Plateau; i.e., without the use of the external high-accuracy gravity data. We use a Louisiana airborne gravity dataset from the USA National Oceanic and Atmospheric Administration (NOAA) to demonstrate that the new method works effectively. Furthermore, and for the Tibetan Plateau we show that the numerical experiment is also successfully conducted using the synthetic Earth Gravitational Model 2008 (EGM08)-derived gravity data contaminated with the synthetic errors. The estimated systematic errors generated by the method are close to the simulated values. In addition, we study the relationship between the downward continuation altitudes and the error effect. The analysis results show that the proposed semi-parametric method combined with regularization is efficient to address such modelling problems.
Zhao, Qilong; Strykowski, Gabriel; Li, Jiancheng; Pan, Xiong; Xu, Xinyu
2017-01-01
Gravity data gaps in mountainous areas are nowadays often filled in with the data from airborne gravity surveys. Because of the errors caused by the airborne gravimeter sensors, and because of rough flight conditions, such errors cannot be completely eliminated. The precision of the gravity disturbances generated by the airborne gravimetry is around 3–5 mgal. A major obstacle in using airborne gravimetry are the errors caused by the downward continuation. In order to improve the results the external high-accuracy gravity information e.g., from the surface data can be used for high frequency correction, while satellite information can be applying for low frequency correction. Surface data may be used to reduce the systematic errors, while regularization methods can reduce the random errors in downward continuation. Airborne gravity surveys are sometimes conducted in mountainous areas and the most extreme area of the world for this type of survey is the Tibetan Plateau. Since there are no high-accuracy surface gravity data available for this area, the above error minimization method involving the external gravity data cannot be used. We propose a semi-parametric downward continuation method in combination with regularization to suppress the systematic error effect and the random error effect in the Tibetan Plateau; i.e., without the use of the external high-accuracy gravity data. We use a Louisiana airborne gravity dataset from the USA National Oceanic and Atmospheric Administration (NOAA) to demonstrate that the new method works effectively. Furthermore, and for the Tibetan Plateau we show that the numerical experiment is also successfully conducted using the synthetic Earth Gravitational Model 2008 (EGM08)-derived gravity data contaminated with the synthetic errors. The estimated systematic errors generated by the method are close to the simulated values. In addition, we study the relationship between the downward continuation altitudes and the error effect. The analysis results show that the proposed semi-parametric method combined with regularization is efficient to address such modelling problems. PMID:28587086
NASA Astrophysics Data System (ADS)
Zhao, Q.
2017-12-01
Gravity data gaps in mountainous areas are nowadays often filled in with the data from airborne gravity surveys. Because of the errors caused by the airborne gravimeter sensors, and because of rough flight conditions, such errors cannot be completely eliminated. The precision of the gravity disturbances generated by the airborne gravimetry is around 3-5 mgal. A major obstacle in using airborne gravimetry are the errors caused by the downward continuation. In order to improve the results the external high-accuracy gravity information e.g., from the surface data can be used for high frequency correction, while satellite information can be applying for low frequency correction. Surface data may be used to reduce the systematic errors, while regularization methods can reduce the random errors in downward continuation. Airborne gravity surveys are sometimes conducted in mountainous areas and the most extreme area of the world for this type of survey is the Tibetan Plateau. Since there are no high-accuracy surface gravity data available for this area, the above error minimization method involving the external gravity data cannot be used. We propose a semi-parametric downward continuation method in combination with regularization to suppress the systematic error effect and the random error effect in the Tibetan Plateau; i.e., without the use of the external high-accuracy gravity data. We use a Louisiana airborne gravity dataset from the USA National Oceanic and Atmospheric Administration (NOAA) to demonstrate that the new method works effectively. Furthermore, and for the Tibetan Plateau we show that the numerical experiment is also successfully conducted using the synthetic Earth Gravitational Model 2008 (EGM08)-derived gravity data contaminated with the synthetic errors. The estimated systematic errors generated by the method are close to the simulated values. In addition, we study the relationship between the downward continuation altitudes and the error effect. The analysis results show that the proposed semi-parametric method combined with regularization is efficient to address such modelling problems.
NASA Technical Reports Server (NTRS)
Heck, M. L.; Findlay, J. T.; Compton, H. R.
1983-01-01
The Aerodynamic Coefficient Identification Package (ACIP) is an instrument consisting of body mounted linear accelerometers, rate gyros, and angular accelerometers for measuring the Space Shuttle vehicular dynamics. The high rate recorded data are utilized for postflight aerodynamic coefficient extraction studies. Although consistent with pre-mission accuracies specified by the manufacturer, the ACIP data were found to contain detectable levels of systematic error, primarily bias, as well as scale factor, static misalignment, and temperature dependent errors. This paper summarizes the technique whereby the systematic ACIP error sources were detected, identified, and calibrated with the use of recorded dynamic data from the low rate, highly accurate Inertial Measurement Units.
Extremal Optimization for estimation of the error threshold in topological subsystem codes at T = 0
NASA Astrophysics Data System (ADS)
Millán-Otoya, Jorge E.; Boettcher, Stefan
2014-03-01
Quantum decoherence is a problem that arises in implementations of quantum computing proposals. Topological subsystem codes (TSC) have been suggested as a way to overcome decoherence. These offer a higher optimal error tolerance when compared to typical error-correcting algorithms. A TSC has been translated into a planar Ising spin-glass with constrained bimodal three-spin couplings. This spin-glass has been considered at finite temperature to determine the phase boundary between the unstable phase and the stable phase, where error recovery is possible.[1] We approach the study of the error threshold problem by exploring ground states of this spin-glass with the Extremal Optimization algorithm (EO).[2] EO has proven to be a effective heuristic to explore ground state configurations of glassy spin-systems.[3
Lau, Billy T; Ji, Hanlee P
2017-09-21
RNA-Seq measures gene expression by counting sequence reads belonging to unique cDNA fragments. Molecular barcodes commonly in the form of random nucleotides were recently introduced to improve gene expression measures by detecting amplification duplicates, but are susceptible to errors generated during PCR and sequencing. This results in false positive counts, leading to inaccurate transcriptome quantification especially at low input and single-cell RNA amounts where the total number of molecules present is minuscule. To address this issue, we demonstrated the systematic identification of molecular species using transposable error-correcting barcodes that are exponentially expanded to tens of billions of unique labels. We experimentally showed random-mer molecular barcodes suffer from substantial and persistent errors that are difficult to resolve. To assess our method's performance, we applied it to the analysis of known reference RNA standards. By including an inline random-mer molecular barcode, we systematically characterized the presence of sequence errors in random-mer molecular barcodes. We observed that such errors are extensive and become more dominant at low input amounts. We described the first study to use transposable molecular barcodes and its use for studying random-mer molecular barcode errors. Extensive errors found in random-mer molecular barcodes may warrant the use of error correcting barcodes for transcriptome analysis as input amounts decrease.
Optical System Error Analysis and Calibration Method of High-Accuracy Star Trackers
Sun, Ting; Xing, Fei; You, Zheng
2013-01-01
The star tracker is a high-accuracy attitude measurement device widely used in spacecraft. Its performance depends largely on the precision of the optical system parameters. Therefore, the analysis of the optical system parameter errors and a precise calibration model are crucial to the accuracy of the star tracker. Research in this field is relatively lacking a systematic and universal analysis up to now. This paper proposes in detail an approach for the synthetic error analysis of the star tracker, without the complicated theoretical derivation. This approach can determine the error propagation relationship of the star tracker, and can build intuitively and systematically an error model. The analysis results can be used as a foundation and a guide for the optical design, calibration, and compensation of the star tracker. A calibration experiment is designed and conducted. Excellent calibration results are achieved based on the calibration model. To summarize, the error analysis approach and the calibration method are proved to be adequate and precise, and could provide an important guarantee for the design, manufacture, and measurement of high-accuracy star trackers. PMID:23567527
Seeing in the Dark: Weak Lensing from the Sloan Digital Sky Survey
NASA Astrophysics Data System (ADS)
Huff, Eric Michael
Statistical weak lensing by large-scale structure { cosmic shear { is a promising cosmological tool, which has motivated the design of several large upcoming astronomical surveys. This Thesis presents a measurement of cosmic shear using coadded Sloan Digital Sky Survey (SDSS) imaging in 168 square degrees of the equatorial region, with r < 23:5 and i < 22:5, a source number density of 2.2 per arcmin2 and median redshift of zmed = 0.52. These coadds were generated using a new rounding kernel method that was intended to minimize systematic errors in the lensing measurement due to coherent PSF anisotropies that are otherwise prevalent in the SDSS imaging data. Measurements of cosmic shear out to angular separations of 2 degrees are presented, along with systematics tests of the catalog generation and shear measurement steps that demonstrate that these results are dominated by statistical rather than systematic errors. Assuming a cosmological model corresponding to WMAP7 (Komatsu et al., 2011) and allowing only the amplitude of matter fluctuations sigma8 to vary, the best-t value of the amplitude of matter fluctuations is sigma 8=0.636+0.109-0.154 (1sigma); without systematic errors this would be sigma8=0.636+0.099 -0.137 (1sigma). Assuming a flat Λ CDM model, the combined constraints with WMAP7 are sigma8=0.784+0.028 -0.026 (1sigma). The 2sigma error range is 14 percent smaller than WMAP7 alone. Aside from the intrinsic value of such cosmological constraints from the growth of structure, some important lessons are identified for upcoming surveys that may face similar issues when combining multi-epoch data to measure cosmic shear. Motivated by the challenges faced in the cosmic shear measurement, two new lensing probes are suggested for increasing the available weak lensing signal. Both use galaxy scaling relations to control for scatter in lensing observables. The first employs a version of the well-known fundamental plane relation for early type galaxies. This modified "photometric fundamental plane" replaces velocity dispersions with photometric galaxy properties, thus obviating the need for spectroscopic data. We present the first detection of magnification using this method by applying it to photometric catalogs from the Sloan Digital Sky Survey. This analysis shows that the derived magnification signal is comparable to that available from conventional methods using gravitational shear. We suppress the dominant sources of systematic error and discuss modest improvements that may allow this method to equal or even surpass the signal-to-noise achievable with shear. Moreover, some of the dominant sources of systematic error are substantially different from those of shear-based techniques. The second outlines an idea for using the optical Tully-Fisher relation to dramatically improve the signal-to-noise and systematic error control for shear measurements. The expected error properties and potential advantages of such a measurement are proposed, and a pilot study is suggested in order to test the viability of Tully-Fisher weak lensing in the context of the forthcoming generation of large spectroscopic surveys.
Savara, Aditya
2017-06-28
There was an error in the original Comment. The entropy term arising from 1/N! should be free from dimensional dependence, but also negative. In the original Comment, the nN A arising from 1/N! was inadvertently moved into the dimensional dependent term of Eqs. 2 and 3. To avoid confusion and to keep the same numbering as before, the equations should be as follows.
Voshall, Barbara; Piscotty, Ronald; Lawrence, Jeanette; Targosz, Mary
2013-10-01
Safe medication administration is necessary to ensure quality healthcare. Barcode medication administration systems were developed to reduce drug administration errors and the related costs and improve patient safety. Work-arounds created by nurses in the execution of the required processes can lead to unintended consequences, including errors. This article provides a systematic review of the literature associated with barcoded medication administration and work-arounds and suggests interventions that should be adopted by nurse executives to ensure medication safety.
NASA Technical Reports Server (NTRS)
Larson, T. J.; Ehernberger, L. J.
1985-01-01
The flight test technique described uses controlled survey runs to determine horizontal atmospheric pressure variations and systematic altitude errors that result from space positioning measurements. The survey data can be used not only for improved air data calibrations, but also for studies of atmospheric structure and space positioning accuracy performance. The examples presented cover a wide range of radar tracking conditions for both subsonic and supersonic flight to an altitude of 42,000 ft.
Systematic errors in long baseline oscillation experiments
DOE Office of Scientific and Technical Information (OSTI.GOV)
Harris, Deborah A.; /Fermilab
This article gives a brief overview of long baseline neutrino experiments and their goals, and then describes the different kinds of systematic errors that are encountered in these experiments. Particular attention is paid to the uncertainties that come about because of imperfect knowledge of neutrino cross sections and more generally how neutrinos interact in nuclei. Near detectors are planned for most of these experiments, and the extent to which certain uncertainties can be reduced by the presence of near detectors is also discussed.
Planck 2015 results. VI. LFI mapmaking
NASA Astrophysics Data System (ADS)
Planck Collaboration; Ade, P. A. R.; Aghanim, N.; Ashdown, M.; Aumont, J.; Baccigalupi, C.; Banday, A. J.; Barreiro, R. B.; Bartolo, N.; Battaner, E.; Benabed, K.; Benoît, A.; Benoit-Lévy, A.; Bernard, J.-P.; Bersanelli, M.; Bielewicz, P.; Bonaldi, A.; Bonavera, L.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Bucher, M.; Burigana, C.; Butler, R. C.; Calabrese, E.; Cardoso, J.-F.; Catalano, A.; Chamballu, A.; Chary, R.-R.; Christensen, P. R.; Colombi, S.; Colombo, L. P. L.; Crill, B. P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R. D.; Davis, R. J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Dickinson, C.; Diego, J. M.; Dole, H.; Donzelli, S.; Doré, O.; Douspis, M.; Ducout, A.; Dupac, X.; Efstathiou, G.; Elsner, F.; Enßlin, T. A.; Eriksen, H. K.; Fergusson, J.; Finelli, F.; Forni, O.; Frailis, M.; Franceschi, E.; Frejsel, A.; Galeotta, S.; Galli, S.; Ganga, K.; Giard, M.; Giraud-Héraud, Y.; Gjerløw, E.; González-Nuevo, J.; Górski, K. M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Hansen, F. K.; Hanson, D.; Harrison, D. L.; Henrot-Versillé, S.; Herranz, D.; Hildebrandt, S. R.; Hivon, E.; Hobson, M.; Holmes, W. A.; Hornstrup, A.; Hovest, W.; Huffenberger, K. M.; Hurier, G.; Jaffe, A. H.; Jaffe, T. R.; Juvela, M.; Keihänen, E.; Keskitalo, R.; Kiiveri, K.; Kisner, T. S.; Knoche, J.; Kunz, M.; Kurki-Suonio, H.; Lähteenmäki, A.; Lamarre, J.-M.; Lasenby, A.; Lattanzi, M.; Lawrence, C. R.; Leahy, J. P.; Leonardi, R.; Lesgourgues, J.; Levrier, F.; Liguori, M.; Lilje, P. B.; Linden-Vørnle, M.; Lindholm, V.; López-Caniego, M.; Lubin, P. M.; Macías-Pérez, J. F.; Maggio, G.; Maino, D.; Mandolesi, N.; Mangilli, A.; Martin, P. G.; Martínez-González, E.; Masi, S.; Matarrese, S.; Mazzotta, P.; McGehee, P.; Meinhold, P. R.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mitra, S.; Montier, L.; Morgante, G.; Mortlock, D.; Moss, A.; Munshi, D.; Murphy, J. A.; Naselsky, P.; Nati, F.; Natoli, P.; Netterfield, C. B.; Nørgaard-Nielsen, H. U.; Novikov, D.; Novikov, I.; Paci, F.; Pagano, L.; Paoletti, D.; Partridge, B.; Pasian, F.; Patanchon, G.; Pearson, T. J.; Perdereau, O.; Perotto, L.; Perrotta, F.; Pettorino, V.; Pierpaoli, E.; Pietrobon, D.; Pointecouteau, E.; Polenta, G.; Pratt, G. W.; Prézeau, G.; Prunet, S.; Puget, J.-L.; Rachen, J. P.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renzi, A.; Rocha, G.; Rosset, C.; Rossetti, M.; Roudier, G.; Rubiño-Martín, J. A.; Rusholme, B.; Sandri, M.; Santos, D.; Savelainen, M.; Scott, D.; Seiffert, M. D.; Shellard, E. P. S.; Spencer, L. D.; Stolyarov, V.; Stompor, R.; Sutton, D.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tauber, J. A.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Tucci, M.; Tuovinen, J.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Vassallo, T.; Vielva, P.; Villa, F.; Wade, L. A.; Wandelt, B. D.; Watson, R.; Wehus, I. K.; Yvon, D.; Zacchei, A.; Zonca, A.
2016-09-01
This paper describes the mapmaking procedure applied to Planck Low Frequency Instrument (LFI) data. The mapmaking step takes as input the calibrated timelines and pointing information. The main products are sky maps of I, Q, and U Stokes components. For the first time, we present polarization maps at LFI frequencies. The mapmaking algorithm is based on a destriping technique, which is enhanced with a noise prior. The Galactic region is masked to reduce errors arising from bandpass mismatch and high signal gradients. We apply horn-uniform radiometer weights to reduce the effects of beam-shape mismatch. The algorithm is the same as used for the 2013 release, apart from small changes in parameter settings. We validate the procedure through simulations. Special emphasis is put on the control of systematics, which is particularly important for accurate polarization analysis. We also produce low-resolution versions of the maps and corresponding noise covariance matrices. These serve as input in later analysis steps and parameter estimation. The noise covariance matrices are validated through noise Monte Carlo simulations. The residual noise in the map products is characterized through analysis of half-ring maps, noise covariance matrices, and simulations.
The SAMI Galaxy Survey: can we trust aperture corrections to predict star formation?
NASA Astrophysics Data System (ADS)
Richards, S. N.; Bryant, J. J.; Croom, S. M.; Hopkins, A. M.; Schaefer, A. L.; Bland-Hawthorn, J.; Allen, J. T.; Brough, S.; Cecil, G.; Cortese, L.; Fogarty, L. M. R.; Gunawardhana, M. L. P.; Goodwin, M.; Green, A. W.; Ho, I.-T.; Kewley, L. J.; Konstantopoulos, I. S.; Lawrence, J. S.; Lorente, N. P. F.; Medling, A. M.; Owers, M. S.; Sharp, R.; Sweet, S. M.; Taylor, E. N.
2016-01-01
In the low-redshift Universe (z < 0.3), our view of galaxy evolution is primarily based on fibre optic spectroscopy surveys. Elaborate methods have been developed to address aperture effects when fixed aperture sizes only probe the inner regions for galaxies of ever decreasing redshift or increasing physical size. These aperture corrections rely on assumptions about the physical properties of galaxies. The adequacy of these aperture corrections can be tested with integral-field spectroscopic data. We use integral-field spectra drawn from 1212 galaxies observed as part of the SAMI Galaxy Survey to investigate the validity of two aperture correction methods that attempt to estimate a galaxy's total instantaneous star formation rate. We show that biases arise when assuming that instantaneous star formation is traced by broad-band imaging, and when the aperture correction is built only from spectra of the nuclear region of galaxies. These biases may be significant depending on the selection criteria of a survey sample. Understanding the sensitivities of these aperture corrections is essential for correct handling of systematic errors in galaxy evolution studies.
Bit Error Probability for Maximum Likelihood Decoding of Linear Block Codes
NASA Technical Reports Server (NTRS)
Lin, Shu; Fossorier, Marc P. C.; Rhee, Dojun
1996-01-01
In this paper, the bit error probability P(sub b) for maximum likelihood decoding of binary linear codes is investigated. The contribution of each information bit to P(sub b) is considered. For randomly generated codes, it is shown that the conventional approximation at high SNR P(sub b) is approximately equal to (d(sub H)/N)P(sub s), where P(sub s) represents the block error probability, holds for systematic encoding only. Also systematic encoding provides the minimum P(sub b) when the inverse mapping corresponding to the generator matrix of the code is used to retrieve the information sequence. The bit error performances corresponding to other generator matrix forms are also evaluated. Although derived for codes with a generator matrix randomly generated, these results are shown to provide good approximations for codes used in practice. Finally, for decoding methods which require a generator matrix with a particular structure such as trellis decoding or algebraic-based soft decision decoding, equivalent schemes that reduce the bit error probability are discussed.
NASA Astrophysics Data System (ADS)
Tedd, B. L.; Strangeways, H. J.; Jones, T. B.
1985-11-01
Systematic ionospheric tilts (SITs) at midlatitudes and the diurnal variation of bearing error for different transmission paths are examined. An explanation of diurnal variations of bearing error based on the dependence of ionospheric tilt on solar zenith angle and plasma transport processes is presented. The effect of vertical ion drift and the momentum transfer of neutral winds is investigated. During the daytime the transmissions are low and photochemical processes control SITs; however, at night transmissions are at higher heights and spatial and temporal variations of plasma transport processes influence SITs. A HF ray tracing technique which uses a three-dimensional ionospheric model based on predictions to simulate SIT-induced bearing errors is described; poor correlation with experimental data is observed and the causes for this are studied. A second model based on measured vertical-sounder data is proposed. Model two is applicable for predicting bearing error for a range of transmission paths and correlates well with experimental data.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kalinin, V.A.; Tarasenko, V.L.; Tselser, L.B.
1988-09-01
Numerical values of the variation in ultrasonic velocity in constructional metal alloys and the measurement errors related to them are systematized. The systematization is based on the measurement results of the group ultrasonic velocity made in the All-Union Scientific-Research Institute for Nondestructive Testing in 1983-1984 and also on the measurement results of the group velocity made by various authors. The variations in ultrasonic velocity were systematized for carbon, low-alloy, and medium-alloy constructional steels; high-alloy iron base alloys; nickel-base heat-resistant alloys; wrought aluminum constructional alloys; titanium alloys; and cast irons and copper alloys.
High-accuracy self-calibration method for dual-axis rotation-modulating RLG-INS
NASA Astrophysics Data System (ADS)
Wei, Guo; Gao, Chunfeng; Wang, Qi; Wang, Qun; Long, Xingwu
2017-05-01
Inertial navigation system has been the core component of both military and civil navigation systems. Dual-axis rotation modulation can completely eliminate the inertial elements constant errors of the three axes to improve the system accuracy. But the error caused by the misalignment angles and the scale factor error cannot be eliminated through dual-axis rotation modulation. And discrete calibration method cannot fulfill requirements of high-accurate calibration of the mechanically dithered ring laser gyroscope navigation system with shock absorbers. This paper has analyzed the effect of calibration error during one modulated period and presented a new systematic self-calibration method for dual-axis rotation-modulating RLG-INS. Procedure for self-calibration of dual-axis rotation-modulating RLG-INS has been designed. The results of self-calibration simulation experiment proved that: this scheme can estimate all the errors in the calibration error model, the calibration precision of the inertial sensors scale factor error is less than 1ppm and the misalignment is less than 5″. These results have validated the systematic self-calibration method and proved its importance for accuracy improvement of dual -axis rotation inertial navigation system with mechanically dithered ring laser gyroscope.
Pattern interpolation in thin films of lamellar, symmetric copolymers on nano-patterned substrates
NASA Astrophysics Data System (ADS)
Detcheverry, Francois; Nagpal, Umang; Liu, Guoliang; Nealey, Paul; de Pablo, Juan
2009-03-01
A molecular model of block copolymer systems is used to conduct a systematic study of the morphologies that arise when thin films of symmetric, lamellar forming block copolymer materials are deposited on nanopatterned surfaces. Over 500 distinct cases are considered. It is found that, in general, three distinct morphologies can arise depending on the strength of the substrate-polymer interactions, the film thickness, and the period of the substrate pattern. The relative stability of those morphologies is determined by direct calculation of the free energy differences. The dynamic propensity of those morphologies to emerge is examined by careful analysis of simulated trajectories. The results of this systematic study are used to interpret recent experimental data for films of polystyrene-PMMA copolymers on chemically nanopatterned surfaces.
Influence of conservative corrections on parameter estimation for extreme-mass-ratio inspirals
NASA Astrophysics Data System (ADS)
Huerta, E. A.; Gair, Jonathan R.
2009-04-01
We present an improved numerical kludge waveform model for circular, equatorial extreme-mass-ratio inspirals (EMRIs). The model is based on true Kerr geodesics, augmented by radiative self-force corrections derived from perturbative calculations, and in this paper for the first time we include conservative self-force corrections that we derive by comparison to post-Newtonian results. We present results of a Monte Carlo simulation of parameter estimation errors computed using the Fisher matrix and also assess the theoretical errors that would arise from omitting the conservative correction terms we include here. We present results for three different types of system, namely, the inspirals of black holes, neutron stars, or white dwarfs into a supermassive black hole (SMBH). The analysis shows that for a typical source (a 10M⊙ compact object captured by a 106M⊙ SMBH at a signal to noise ratio of 30) we expect to determine the two masses to within a fractional error of ˜10-4, measure the spin parameter q to ˜10-4.5, and determine the location of the source on the sky and the spin orientation to within 10-3 steradians. We show that, for this kludge model, omitting the conservative corrections leads to a small error over much of the parameter space, i.e., the ratio R of the theoretical model error to the Fisher matrix error is R<1 for all ten parameters in the model. For the few systems with larger errors typically R<3 and hence the conservative corrections can be marginally ignored. In addition, we use our model and first-order self-force results for Schwarzschild black holes to estimate the error that arises from omitting the second-order radiative piece of the self-force. This indicates that it may not be necessary to go beyond first order to recover accurate parameter estimates.
Numerical Error Estimation with UQ
NASA Astrophysics Data System (ADS)
Ackmann, Jan; Korn, Peter; Marotzke, Jochem
2014-05-01
Ocean models are still in need of means to quantify model errors, which are inevitably made when running numerical experiments. The total model error can formally be decomposed into two parts, the formulation error and the discretization error. The formulation error arises from the continuous formulation of the model not fully describing the studied physical process. The discretization error arises from having to solve a discretized model instead of the continuously formulated model. Our work on error estimation is concerned with the discretization error. Given a solution of a discretized model, our general problem statement is to find a way to quantify the uncertainties due to discretization in physical quantities of interest (diagnostics), which are frequently used in Geophysical Fluid Dynamics. The approach we use to tackle this problem is called the "Goal Error Ensemble method". The basic idea of the Goal Error Ensemble method is that errors in diagnostics can be translated into a weighted sum of local model errors, which makes it conceptually based on the Dual Weighted Residual method from Computational Fluid Dynamics. In contrast to the Dual Weighted Residual method these local model errors are not considered deterministically but interpreted as local model uncertainty and described stochastically by a random process. The parameters for the random process are tuned with high-resolution near-initial model information. However, the original Goal Error Ensemble method, introduced in [1], was successfully evaluated only in the case of inviscid flows without lateral boundaries in a shallow-water framework and is hence only of limited use in a numerical ocean model. Our work consists in extending the method to bounded, viscous flows in a shallow-water framework. As our numerical model, we use the ICON-Shallow-Water model. In viscous flows our high-resolution information is dependent on the viscosity parameter, making our uncertainty measures viscosity-dependent. We will show that we can choose a sensible parameter by using the Reynolds-number as a criteria. Another topic, we will discuss is the choice of the underlying distribution of the random process. This is especially of importance in the scope of lateral boundaries. We will present resulting error estimates for different height- and velocity-based diagnostics applied to the Munk gyre experiment. References [1] F. RAUSER: Error Estimation in Geophysical Fluid Dynamics through Learning; PhD Thesis, IMPRS-ESM, Hamburg, 2010 [2] F. RAUSER, J. MAROTZKE, P. KORN: Ensemble-type numerical uncertainty quantification from single model integrations; SIAM/ASA Journal on Uncertainty Quantification, submitted
Structure from Motion (SfM) photogrammetry applied to historical imagery: plug & play?
NASA Astrophysics Data System (ADS)
Bakker, Maarten; Lane, Stuart N.
2017-04-01
The development of Structure from Motion (SfM) photogrammetry has led to a vast increase and expansion of geomorphological applications. Highly detailed Digital Elevation Models (DEMs) can be efficiently generated from a variety of platforms that cover a large range of spatial scales. For the application of DEMs in geomorphic change analysis, precision and spatial resolution are not of sole importance, but also their accuracy, temporal resolution and temporal coverage. The use of archival imagery may substantially lengthen temporal coverage, allowing quantification of annual to decadal scale landform change. Whilst archival photogrammetry is not new, a question arises as to how applicable SfM methods are as a more cost-effective and straightforward alternative to the conventional approach. Here, we studied a relatively extreme case where we applied SfM techniques to archival aerial imagery, to investigate the decadal evolution of a low relief braided river. The Borgne is an Alpine river in south-west Switzerland which is strongly affected by flow abstraction for hydropower, allowing the fairly straightforward application of photogrammetry on the near-dry river bed. For 8 sets of scanned historical aerial images in the period 1959-2005 we performed Ground Control Point (GCP) assisted bundle adjustment using both classical archival digital photogrammetry (used as a reference dataset) and SfM based photogrammetry. For the SfM method, no further data were used to constrain camera or exterior orientation parameters a priori, but instead we used these for a posteriori verification. The resulting densified point clouds were registered onto a reference surface based on stable areas, allowing the correction for any systematic error in DEMs that may arise from (random) error in the bundle adjustment. The obtained results show that the quality of the SfM based bundle adjustment is similar to that of the classical photogrammetric approach. Next to image scale, the quality is strongly driven by ability of computer vision techniques to extract tie-points, which is controlled by image texture (quantified here using entropy) and image overlap (redundancy). Depending on the used image set, these characteristics may therefore be effectively exploited or pose a limitation for application. The quality of the results aside, we found that the recovered bundle adjustment parameters were not necessarily correct and that there was the possibility for a trade-off, between estimated focal length and camera flying height for example, such that the right results were obtained if not for the right reasons. This highlights the need to assess camera and exterior orientation parameters, and to address systematic errors that may evolve from this. For the latter, we found that point cloud registration is crucial, particularly in a low relief environment such as a braided river, for accurate change quantification and geomorphic interpretation. We conclude that, given a suitable set of images and considering principles of classical photogrammetric analysis, SfM methods can be effectively applied for archival imagery analysis, but that this is by no means a plug and play methodology.
The role of the basic state in the ENSO-monsoon relationship and implications for predictability
NASA Astrophysics Data System (ADS)
Turner, A. G.; Inness, P. M.; Slingo, J. M.
2005-04-01
The impact of systematic model errors on a coupled simulation of the Asian summer monsoon and its interannual variability is studied. Although the mean monsoon climate is reasonably well captured, systematic errors in the equatorial Pacific mean that the monsoon-ENSO teleconnection is rather poorly represented in the general-circulation model. A system of ocean-surface heat flux adjustments is implemented in the tropical Pacific and Indian Oceans in order to reduce the systematic biases. In this version of the general-circulation model, the monsoon-ENSO teleconnection is better simulated, particularly the lag-lead relationships in which weak monsoons precede the peak of El Niño. In part this is related to changes in the characteristics of El Niño, which has a more realistic evolution in its developing phase. A stronger ENSO amplitude in the new model version also feeds back to further strengthen the teleconnection. These results have important implications for the use of coupled models for seasonal prediction of systems such as the monsoon, and suggest that some form of flux correction may have significant benefits where model systematic error compromises important teleconnections and modes of interannual variability.
NASA Astrophysics Data System (ADS)
Gruszczynska, Marta; Rosat, Severine; Klos, Anna; Gruszczynski, Maciej; Bogusz, Janusz
2018-03-01
We described a spatio-temporal analysis of environmental loading models: atmospheric, continental hydrology, and non-tidal ocean changes, based on multichannel singular spectrum analysis (MSSA). We extracted the common annual signal for 16 different sections related to climate zones: equatorial, arid, warm, snow, polar and continents. We used the loading models estimated for a set of 229 ITRF2014 (International Terrestrial Reference Frame) International GNSS Service (IGS) stations and discussed the amount of variance explained by individual modes, proving that the common annual signal accounts for 16, 24 and 68% of the total variance of non-tidal ocean, atmospheric and hydrological loading models, respectively. Having removed the common environmental MSSA seasonal curve from the corresponding GPS position time series, we found that the residual station-specific annual curve modelled with the least-squares estimation has the amplitude of maximum 2 mm. This means that the environmental loading models underestimate the seasonalities observed by the GPS system. The remaining signal present in the seasonal frequency band arises from the systematic errors which are not of common environmental or geophysical origin. Using common mode error (CME) estimates, we showed that the direct removal of environmental loading models from the GPS series causes an artificial loss in the CME power spectra between 10 and 80 cycles per year. When environmental effect is removed from GPS series with MSSA curves, no influence on the character of spectra of CME estimates was noticed.
The Disk Wind in the Rapidly Spinning Stellar-mass Black Hole 4U 1630-472 Observed with NuSTAR
NASA Technical Reports Server (NTRS)
King, Ashley L.; Walton, Dominic J.; Miller, Jon M.; Barret, Didier; Boggs, Steven E.; Christensen, Finn E.; Craig, William W.; Fabian, Andy C.; Furst, Felix; Hailey, Charles J.;
2014-01-01
We present an analysis of a short NuSTAR observation of the stellar-mass black hole and low-mass X-ray binary 4U 1630-472. Reflection from the inner accretion disk is clearly detected for the first time in this source, owing to the sensitivity of NuSTAR. With fits to the reflection spectrum, we find evidence for a rapidly spinning black hole, a* = 0.985(+0.005/-0.014) (1 sigma statistical errors). However, archival data show that the source has relatively low radio luminosity. Recently claimed relationships between jet power and black hole spin would predict either a lower spin or a higher peak radio luminosity. We also report the clear detection of an absorption feature at 7.03 +/- 0.03 keV, likely signaling a disk wind. If this line arises in dense, moderately ionized gas (log xi = 3.6(+0.2/-0.3) and is dominated by He-like Fe xxv, the wind has a velocity of v/c = 0.043(+0.002/-0.007) (12900(+600/-2100) km s(exp -1)). If the line is instead associated with a more highly ionized gas (log xi = 6.1(+0.7/-0.6)), and is dominated by Fe xxvi, evidence of a blueshift is only marginal, after taking systematic errors into account. Our analysis suggests the ionized wind may be launched within 200-1100 Rg, and may be magnetically driven.
Datta, Rakesh; Khanna, Sangeeta
2017-10-01
Commanding a military multinational and multilingual healthcare facility can be a formidable task with very little margin for error. The authors were in leadership positions of UNIFIL Hospital, unique in its diversity of both staff and clientele. Experience about the challenges faced and methods adopted to overcome them will be shared. Troops from diverse backgrounds differ in their competency, and also in their attitudinal approach to situations. It is imperative for the medical commanders to identify these differences, and work towards harnessing individual strengths to form a cohesive unit. Frequent rotation of team members and thereby difficulty in adapting to new environment makes the tasks more challenging. Challenges can be broadly categorized in those dealing with functional roles (providing medical support) and command and control issues. Linguistic challenges especially in situations where professionals have to work as a coordinated unit remains a major challenge. The threat of medical errors arising out of misunderstandings is very real. Gender sensitization is essential to avoid potential unpleasant situations. Interpersonal conflict can easily go out of hand. The leadership has to be more direct and deliberate relying less on hierarchy and more on direct communication. A strict enforcement of UN standards for equipment and competence, frequent joint medical drills help to overcome interoperability issues and develop mutual confidence. Leadership in multinational UN hospitals is a demanding task with its peculiar set of challenges. A systematic and deliberate approach focused on mutual respect, flexibility and direct leadership can help medical commanders in such situations.
NASA Astrophysics Data System (ADS)
Gruszczynska, Marta; Rosat, Severine; Klos, Anna; Gruszczynski, Maciej; Bogusz, Janusz
2018-05-01
We described a spatio-temporal analysis of environmental loading models: atmospheric, continental hydrology, and non-tidal ocean changes, based on multichannel singular spectrum analysis (MSSA). We extracted the common annual signal for 16 different sections related to climate zones: equatorial, arid, warm, snow, polar and continents. We used the loading models estimated for a set of 229 ITRF2014 (International Terrestrial Reference Frame) International GNSS Service (IGS) stations and discussed the amount of variance explained by individual modes, proving that the common annual signal accounts for 16, 24 and 68% of the total variance of non-tidal ocean, atmospheric and hydrological loading models, respectively. Having removed the common environmental MSSA seasonal curve from the corresponding GPS position time series, we found that the residual station-specific annual curve modelled with the least-squares estimation has the amplitude of maximum 2 mm. This means that the environmental loading models underestimate the seasonalities observed by the GPS system. The remaining signal present in the seasonal frequency band arises from the systematic errors which are not of common environmental or geophysical origin. Using common mode error (CME) estimates, we showed that the direct removal of environmental loading models from the GPS series causes an artificial loss in the CME power spectra between 10 and 80 cycles per year. When environmental effect is removed from GPS series with MSSA curves, no influence on the character of spectra of CME estimates was noticed.
A Bayesian Approach to Systematic Error Correction in Kepler Photometric Time Series
NASA Astrophysics Data System (ADS)
Jenkins, Jon Michael; VanCleve, J.; Twicken, J. D.; Smith, J. C.; Kepler Science Team
2011-01-01
In order for the Kepler mission to achieve its required 20 ppm photometric precision for 6.5 hr observations of 12th magnitude stars, the Presearch Data Conditioning (PDC) software component of the Kepler Science Processing Pipeline must reduce systematic errors in flux time series to the limit of stochastic noise for errors with time-scales less than three days, without smoothing or over-fitting away the transits that Kepler seeks. The current version of PDC co-trends against ancillary engineering data and Pipeline generated data using essentially a least squares (LS) approach. This approach is successful for quiet stars when all sources of systematic error have been identified. If the stars are intrinsically variable or some sources of systematic error are unknown, LS will nonetheless attempt to explain all of a given time series, not just the part the model can explain well. Negative consequences can include loss of astrophysically interesting signal, and injection of high-frequency noise into the result. As a remedy, we present a Bayesian Maximum A Posteriori (MAP) approach, in which a subset of intrinsically quiet and highly-correlated stars is used to establish the probability density function (PDF) of robust fit parameters in a diagonalized basis. The PDFs then determine a "reasonable” range for the fit parameters for all stars, and brake the runaway fitting that can distort signals and inject noise. We present a closed-form solution for Gaussian PDFs, and show examples using publically available Quarter 1 Kepler data. A companion poster (Van Cleve et al.) shows applications and discusses current work in more detail. Kepler was selected as the 10th mission of the Discovery Program. Funding for this mission is provided by NASA, Science Mission Directorate.
Systematic error of the Gaia DR1 TGAS parallaxes from data for the red giant clump
NASA Astrophysics Data System (ADS)
Gontcharov, G. A.
2017-08-01
Based on the Gaia DR1 TGAS parallaxes and photometry from the Tycho-2, Gaia, 2MASS, andWISE catalogues, we have produced a sample of 100 000 clump red giants within 800 pc of the Sun. The systematic variations of the mode of their absolute magnitude as a function of the distance, magnitude, and other parameters have been analyzed. We show that these variations reach 0.7 mag and cannot be explained by variations in the interstellar extinction or intrinsic properties of stars and by selection. The only explanation seems to be a systematic error of the Gaia DR1 TGAS parallax dependent on the square of the observed distance in kpc: 0.18 R 2 mas. Allowance for this error reduces significantly the systematic dependences of the absolute magnitude mode on all parameters. This error reaches 0.1 mas within 800 pc of the Sun and allows an upper limit for the accuracy of the TGAS parallaxes to be estimated as 0.2 mas. A careful allowance for such errors is needed to use clump red giants as "standard candles." This eliminates all discrepancies between the theoretical and empirical estimates of the characteristics of these stars and allows us to obtain the first estimates of the modes of their absolute magnitudes from the Gaia parallaxes: mode( M H ) = -1.49 m ± 0.04 m , mode( M Ks ) = -1.63 m ± 0.03 m , mode( M W1) = -1.67 m ± 0.05 m mode( M W2) = -1.67 m ± 0.05 m , mode( M W3) = -1.66 m ± 0.02 m , mode( M W4) = -1.73 m ± 0.03 m , as well as the corresponding estimates of their de-reddened colors.
NASA Technical Reports Server (NTRS)
Ramirez, Daniel Perez; Whiteman, David N.; Veselovskii, Igor; Kolgotin, Alexei; Korenskiy, Michael; Alados-Arboledas, Lucas
2013-01-01
In this work we study the effects of systematic and random errors on the inversion of multiwavelength (MW) lidar data using the well-known regularization technique to obtain vertically resolved aerosol microphysical properties. The software implementation used here was developed at the Physics Instrumentation Center (PIC) in Troitsk (Russia) in conjunction with the NASA/Goddard Space Flight Center. Its applicability to Raman lidar systems based on backscattering measurements at three wavelengths (355, 532 and 1064 nm) and extinction measurements at two wavelengths (355 and 532 nm) has been demonstrated widely. The systematic error sensitivity is quantified by first determining the retrieved parameters for a given set of optical input data consistent with three different sets of aerosol physical parameters. Then each optical input is perturbed by varying amounts and the inversion is repeated. Using bimodal aerosol size distributions, we find a generally linear dependence of the retrieved errors in the microphysical properties on the induced systematic errors in the optical data. For the retrievals of effective radius, number/surface/volume concentrations and fine-mode radius and volume, we find that these results are not significantly affected by the range of the constraints used in inversions. But significant sensitivity was found to the allowed range of the imaginary part of the particle refractive index. Our results also indicate that there exists an additive property for the deviations induced by the biases present in the individual optical data. This property permits the results here to be used to predict deviations in retrieved parameters when multiple input optical data are biased simultaneously as well as to study the influence of random errors on the retrievals. The above results are applied to questions regarding lidar design, in particular for the spaceborne multiwavelength lidar under consideration for the upcoming ACE mission.
NASA Astrophysics Data System (ADS)
Appleby, Graham; Rodríguez, José; Altamimi, Zuheir
2016-12-01
Satellite laser ranging (SLR) to the geodetic satellites LAGEOS and LAGEOS-2 uniquely determines the origin of the terrestrial reference frame and, jointly with very long baseline interferometry, its scale. Given such a fundamental role in satellite geodesy, it is crucial that any systematic errors in either technique are at an absolute minimum as efforts continue to realise the reference frame at millimetre levels of accuracy to meet the present and future science requirements. Here, we examine the intrinsic accuracy of SLR measurements made by tracking stations of the International Laser Ranging Service using normal point observations of the two LAGEOS satellites in the period 1993 to 2014. The approach we investigate in this paper is to compute weekly reference frame solutions solving for satellite initial state vectors, station coordinates and daily Earth orientation parameters, estimating along with these weekly average range errors for each and every one of the observing stations. Potential issues in any of the large number of SLR stations assumed to have been free of error in previous realisations of the ITRF may have been absorbed in the reference frame, primarily in station height. Likewise, systematic range errors estimated against a fixed frame that may itself suffer from accuracy issues will absorb network-wide problems into station-specific results. Our results suggest that in the past two decades, the scale of the ITRF derived from the SLR technique has been close to 0.7 ppb too small, due to systematic errors either or both in the range measurements and their treatment. We discuss these results in the context of preparations for ITRF2014 and additionally consider the impact of this work on the currently adopted value of the geocentric gravitational constant, GM.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Li, T. S.; DePoy, D. L.; Marshall, J. L.
Here, we report that meeting the science goals for many current and future ground-based optical large-area sky surveys requires that the calibrated broadband photometry is both stable in time and uniform over the sky to 1% precision or better. Past and current surveys have achieved photometric precision of 1%–2% by calibrating the survey's stellar photometry with repeated measurements of a large number of stars observed in multiple epochs. The calibration techniques employed by these surveys only consider the relative frame-by-frame photometric zeropoint offset and the focal plane position-dependent illumination corrections, which are independent of the source color. However, variations inmore » the wavelength dependence of the atmospheric transmission and the instrumental throughput induce source color-dependent systematic errors. These systematic errors must also be considered to achieve the most precise photometric measurements. In this paper, we examine such systematic chromatic errors (SCEs) using photometry from the Dark Energy Survey (DES) as an example. We first define a natural magnitude system for DES and calculate the systematic errors on stellar magnitudes when the atmospheric transmission and instrumental throughput deviate from the natural system. We conclude that the SCEs caused by the change of airmass in each exposure, the change of the precipitable water vapor and aerosol in the atmosphere over time, and the non-uniformity of instrumental throughput over the focal plane can be up to 2% in some bandpasses. We then compare the calculated SCEs with the observed DES data. For the test sample data, we correct these errors using measurements of the atmospheric transmission and instrumental throughput from auxiliary calibration systems. In conclusion, the residual after correction is less than 0.3%. Moreover, we calculate such SCEs for Type Ia supernovae and elliptical galaxies and find that the chromatic errors for non-stellar objects are redshift-dependent and can be larger than those for stars at certain redshifts.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Li, T. S.; DePoy, D. L.; Marshall, J. L.
Meeting the science goals for many current and future ground-based optical large-area sky surveys requires that the calibrated broadband photometry is both stable in time and uniform over the sky to 1% precision or better. Past and current surveys have achieved photometric precision of 1%–2% by calibrating the survey’s stellar photometry with repeated measurements of a large number of stars observed in multiple epochs. The calibration techniques employed by these surveys only consider the relative frame-by-frame photometric zeropoint offset and the focal plane position-dependent illumination corrections, which are independent of the source color. However, variations in the wavelength dependence ofmore » the atmospheric transmission and the instrumental throughput induce source color-dependent systematic errors. These systematic errors must also be considered to achieve the most precise photometric measurements. In this paper, we examine such systematic chromatic errors (SCEs) using photometry from the Dark Energy Survey (DES) as an example. We first define a natural magnitude system for DES and calculate the systematic errors on stellar magnitudes when the atmospheric transmission and instrumental throughput deviate from the natural system. We conclude that the SCEs caused by the change of airmass in each exposure, the change of the precipitable water vapor and aerosol in the atmosphere over time, and the non-uniformity of instrumental throughput over the focal plane can be up to 2% in some bandpasses. We then compare the calculated SCEs with the observed DES data. For the test sample data, we correct these errors using measurements of the atmospheric transmission and instrumental throughput from auxiliary calibration systems. The residual after correction is less than 0.3%. Moreover, we calculate such SCEs for Type Ia supernovae and elliptical galaxies and find that the chromatic errors for non-stellar objects are redshift-dependent and can be larger than those for stars at certain redshifts.« less
Leyland, M J; Beurskens, M N A; Flanagan, J C; Frassinetti, L; Gibson, K J; Kempenaars, M; Maslov, M; Scannell, R
2016-01-01
The Joint European Torus (JET) high resolution Thomson scattering (HRTS) system measures radial electron temperature and density profiles. One of the key capabilities of this diagnostic is measuring the steep pressure gradient, termed the pedestal, at the edge of JET plasmas. The pedestal is susceptible to limiting instabilities, such as Edge Localised Modes (ELMs), characterised by a periodic collapse of the steep gradient region. A common method to extract the pedestal width, gradient, and height, used on numerous machines, is by performing a modified hyperbolic tangent (mtanh) fit to overlaid profiles selected from the same region of the ELM cycle. This process of overlaying profiles, termed ELM synchronisation, maximises the number of data points defining the pedestal region for a given phase of the ELM cycle. When fitting to HRTS profiles, it is necessary to incorporate the diagnostic radial instrument function, particularly important when considering the pedestal width. A deconvolved fit is determined by a forward convolution method requiring knowledge of only the instrument function and profiles. The systematic error due to the deconvolution technique incorporated into the JET pedestal fitting tool has been documented by Frassinetti et al. [Rev. Sci. Instrum. 83, 013506 (2012)]. This paper seeks to understand and quantify the systematic error introduced to the pedestal width due to ELM synchronisation. Synthetic profiles, generated with error bars and point-to-point variation characteristic of real HRTS profiles, are used to evaluate the deviation from the underlying pedestal width. We find on JET that the ELM synchronisation systematic error is negligible in comparison to the statistical error when assuming ten overlaid profiles (typical for a pre-ELM fit to HRTS profiles). This confirms that fitting a mtanh to ELM synchronised profiles is a robust and practical technique for extracting the pedestal structure.
Baron, Charles A.; Awan, Musaddiq J.; Mohamed, Abdallah S. R.; Akel, Imad; Rosenthal, David I.; Gunn, G. Brandon; Garden, Adam S.; Dyer, Brandon A.; Court, Laurence; Sevak, Parag R; Kocak-Uzel, Esengul; Fuller, Clifton D.
2016-01-01
Larynx may alternatively serve as a target or organ-at-risk (OAR) in head and neck cancer (HNC) image-guided radiotherapy (IGRT). The objective of this study was to estimate IGRT parameters required for larynx positional error independent of isocentric alignment and suggest population–based compensatory margins. Ten HNC patients receiving radiotherapy (RT) with daily CT-on-rails imaging were assessed. Seven landmark points were placed on each daily scan. Taking the most superior anterior point of the C5 vertebra as a reference isocenter for each scan, residual displacement vectors to the other 6 points were calculated post-isocentric alignment. Subsequently, using the first scan as a reference, the magnitude of vector differences for all 6 points for all scans over the course of treatment were calculated. Residual systematic and random error, and the necessary compensatory CTV-to-PTV and OAR-to-PRV margins were calculated, using both observational cohort data and a bootstrap-resampled population estimator. The grand mean displacements for all anatomical points was 5.07mm, with mean systematic error of 1.1mm and mean random setup error of 2.63mm, while bootstrapped POIs grand mean displacement was 5.09mm, with mean systematic error of 1.23mm and mean random setup error of 2.61mm. Required margin for CTV-PTV expansion was 4.6mm for all cohort points, while the bootstrap estimator of the equivalent margin was 4.9mm. The calculated OAR-to-PRV expansion for the observed residual set-up error was 2.7mm, and bootstrap estimated expansion of 2.9mm. We conclude that the interfractional larynx setup error is a significant source of RT set-up/delivery error in HNC both when the larynx is considered as a CTV or OAR. We estimate the need for a uniform expansion of 5mm to compensate for set up error if the larynx is a target or 3mm if the larynx is an OAR when using a non-laryngeal bony isocenter. PMID:25679151
Baron, Charles A.; Awan, Musaddiq J.; Mohamed, Abdallah S.R.; Akel, Imad; Rosenthal, David I.; Gunn, G. Brandon; Garden, Adam S.; Dyer, Brandon A.; Court, Laurence; Sevak, Parag R.; Kocak‐Uzel, Esengul
2014-01-01
Larynx may alternatively serve as a target or organs at risk (OAR) in head and neck cancer (HNC) image‐guided radiotherapy (IGRT). The objective of this study was to estimate IGRT parameters required for larynx positional error independent of isocentric alignment and suggest population‐based compensatory margins. Ten HNC patients receiving radiotherapy (RT) with daily CT on‐rails imaging were assessed. Seven landmark points were placed on each daily scan. Taking the most superior‐anterior point of the C5 vertebra as a reference isocenter for each scan, residual displacement vectors to the other six points were calculated postisocentric alignment. Subsequently, using the first scan as a reference, the magnitude of vector differences for all six points for all scans over the course of treatment was calculated. Residual systematic and random error and the necessary compensatory CTV‐to‐PTV and OAR‐to‐PRV margins were calculated, using both observational cohort data and a bootstrap‐resampled population estimator. The grand mean displacements for all anatomical points was 5.07 mm, with mean systematic error of 1.1 mm and mean random setup error of 2.63 mm, while bootstrapped POIs grand mean displacement was 5.09 mm, with mean systematic error of 1.23 mm and mean random setup error of 2.61 mm. Required margin for CTV‐PTV expansion was 4.6 mm for all cohort points, while the bootstrap estimator of the equivalent margin was 4.9 mm. The calculated OAR‐to‐PRV expansion for the observed residual setup error was 2.7 mm and bootstrap estimated expansion of 2.9 mm. We conclude that the interfractional larynx setup error is a significant source of RT setup/delivery error in HNC, both when the larynx is considered as a CTV or OAR. We estimate the need for a uniform expansion of 5 mm to compensate for setup error if the larynx is a target, or 3 mm if the larynx is an OAR, when using a nonlaryngeal bony isocenter. PACS numbers: 87.55.D‐, 87.55.Qr
Functional Independent Scaling Relation for ORR/OER Catalysts
Christensen, Rune; Hansen, Heine A.; Dickens, Colin F.; ...
2016-10-11
A widely used adsorption energy scaling relation between OH* and OOH* intermediates in the oxygen reduction reaction (ORR) and oxygen evolution reaction (OER), has previously been determined using density functional theory and shown to dictate a minimum thermodynamic overpotential for both reactions. Here, we show that the oxygen–oxygen bond in the OOH* intermediate is, however, not well described with the previously used class of exchange-correlation functionals. By quantifying and correcting the systematic error, an improved description of gaseous peroxide species versus experimental data and a reduction in calculational uncertainty is obtained. For adsorbates, we find that the systematic error largelymore » cancels the vdW interaction missing in the original determination of the scaling relation. An improved scaling relation, which is fully independent of the applied exchange–correlation functional, is obtained and found to differ by 0.1 eV from the original. Lastly, this largely confirms that, although obtained with a method suffering from systematic errors, the previously obtained scaling relation is applicable for predictions of catalytic activity.« less
Wolf, Dwayne A; Drake, Stacy A; Snow, Francine K
2017-12-01
In the course of fulfilling their statutory role, physicians performing medicolegal investigations may recognize clinical colleagues' medical errors. If the error is found to have led directly to the patient's death (missed diagnosis or incorrect diagnosis, for example), then the forensic pathologist has a professional responsibility to include the information in the autopsy report and make sure that the family is appropriately informed. When the error is significant but did not lead directly to the patient's demise, ethical questions may arise regarding the obligations of the medical examiner to disclose the error to the clinicians or to the family. This case depicts the discovery of medical error likely unrelated to the cause of death and describes one possible ethical approach to disclosure derived from an ethical reasoning model addressing ethical principles of respect for persons/autonomy, beneficence, nonmaleficence, and justice.
Scherer, Laura D; Yates, J Frank; Baker, S Glenn; Valentine, Kathrene D
2017-06-01
Human judgment often violates normative standards, and virtually no judgment error has received as much attention as the conjunction fallacy. Judgment errors have historically served as evidence for dual-process theories of reasoning, insofar as these errors are assumed to arise from reliance on a fast and intuitive mental process, and are corrected via effortful deliberative reasoning. In the present research, three experiments tested the notion that conjunction errors are reduced by effortful thought. Predictions based on three different dual-process theory perspectives were tested: lax monitoring, override failure, and the Tripartite Model. Results indicated that participants higher in numeracy were less likely to make conjunction errors, but this association only emerged when participants engaged in two-sided reasoning, as opposed to one-sided or no reasoning. Confidence was higher for incorrect as opposed to correct judgments, suggesting that participants were unaware of their errors.
Hessian matrix approach for determining error field sensitivity to coil deviations
NASA Astrophysics Data System (ADS)
Zhu, Caoxiang; Hudson, Stuart R.; Lazerson, Samuel A.; Song, Yuntao; Wan, Yuanxi
2018-05-01
The presence of error fields has been shown to degrade plasma confinement and drive instabilities. Error fields can arise from many sources, but are predominantly attributed to deviations in the coil geometry. In this paper, we introduce a Hessian matrix approach for determining error field sensitivity to coil deviations. A primary cost function used for designing stellarator coils, the surface integral of normalized normal field errors, was adopted to evaluate the deviation of the generated magnetic field from the desired magnetic field. The FOCUS code (Zhu et al 2018 Nucl. Fusion 58 016008) is utilized to provide fast and accurate calculations of the Hessian. The sensitivities of error fields to coil displacements are then determined by the eigenvalues of the Hessian matrix. A proof-of-principle example is given on a CNT-like configuration. We anticipate that this new method could provide information to avoid dominant coil misalignments and simplify coil designs for stellarators.
Effects of waveform model systematics on the interpretation of GW150914
NASA Astrophysics Data System (ADS)
Abbott, B. P.; Abbott, R.; Abbott, T. D.; Abernathy, M. R.; Acernese, F.; Ackley, K.; Adams, C.; Adams, T.; Addesso, P.; Adhikari, R. X.; Adya, V. B.; Affeldt, C.; Agathos, M.; Agatsuma, K.; Aggarwal, N.; Aguiar, O. D.; Aiello, L.; Ain, A.; Ajith, P.; Allen, B.; Allocca, A.; Altin, P. A.; Ananyeva, A.; Anderson, S. B.; Anderson, W. G.; Appert, S.; Arai, K.; Araya, M. C.; Areeda, J. S.; Arnaud, N.; Arun, K. G.; Ascenzi, S.; Ashton, G.; Ast, M.; Aston, S. M.; Astone, P.; Aufmuth, P.; Aulbert, C.; Avila-Alvarez, A.; Babak, S.; Bacon, P.; Bader, M. K. M.; Baker, P. T.; Baldaccini, F.; Ballardin, G.; Ballmer, S. W.; Barayoga, J. C.; E Barclay, S.; Barish, B. C.; Barker, D.; Barone, F.; Barr, B.; Barsotti, L.; Barsuglia, M.; Barta, D.; Bartlett, J.; Bartos, I.; Bassiri, R.; Basti, A.; Batch, J. C.; Baune, C.; Bavigadda, V.; Bazzan, M.; Beer, C.; Bejger, M.; Belahcene, I.; Belgin, M.; Bell, A. S.; Berger, B. K.; Bergmann, G.; Berry, C. P. L.; Bersanetti, D.; Bertolini, A.; Betzwieser, J.; Bhagwat, S.; Bhandare, R.; Bilenko, I. A.; Billingsley, G.; Billman, C. R.; Birch, J.; Birney, R.; Birnholtz, O.; Biscans, S.; Bisht, A.; Bitossi, M.; Biwer, C.; Bizouard, M. A.; Blackburn, J. K.; Blackman, J.; Blair, C. D.; Blair, D. G.; Blair, R. M.; Bloemen, S.; Bock, O.; Boer, M.; Bogaert, G.; Bohe, A.; Bondu, F.; Bonnand, R.; Boom, B. A.; Bork, R.; Boschi, V.; Bose, S.; Bouffanais, Y.; Bozzi, A.; Bradaschia, C.; Brady, P. R.; Braginsky, V. B.; Branchesi, M.; E Brau, J.; Briant, T.; Brillet, A.; Brinkmann, M.; Brisson, V.; Brockill, P.; E Broida, J.; Brooks, A. F.; Brown, D. A.; Brown, D. D.; Brown, N. M.; Brunett, S.; Buchanan, C. C.; Buikema, A.; Bulik, T.; Bulten, H. J.; Buonanno, A.; Buskulic, D.; Buy, C.; Byer, R. L.; Cabero, M.; Cadonati, L.; Cagnoli, G.; Cahillane, C.; Calderón Bustillo, J.; Callister, T. A.; Calloni, E.; Camp, J. B.; Cannon, K. C.; Cao, H.; Cao, J.; Capano, C. D.; Capocasa, E.; Carbognani, F.; Caride, S.; Casanueva Diaz, J.; Casentini, C.; Caudill, S.; Cavaglià, M.; Cavalier, F.; Cavalieri, R.; Cella, G.; Cepeda, C. B.; Cerboni Baiardi, L.; Cerretani, G.; Cesarini, E.; Chamberlin, S. J.; Chan, M.; Chao, S.; Charlton, P.; Chassande-Mottin, E.; Cheeseboro, B. D.; Chen, H. Y.; Chen, Y.; Cheng, H.-P.; Chincarini, A.; Chiummo, A.; Chmiel, T.; Cho, H. S.; Cho, M.; Chow, J. H.; Christensen, N.; Chu, Q.; Chua, A. J. K.; Chua, S.; Chung, S.; Ciani, G.; Clara, F.; Clark, J. A.; Cleva, F.; Cocchieri, C.; Coccia, E.; Cohadon, P.-F.; Colla, A.; Collette, C. G.; Cominsky, L.; Constancio, M., Jr.; Conti, L.; Cooper, S. J.; Corbitt, T. R.; Cornish, N.; Corsi, A.; Cortese, S.; Costa, C. A.; Coughlin, M. W.; Coughlin, S. B.; Coulon, J.-P.; Countryman, S. T.; Couvares, P.; Covas, P. B.; E Cowan, E.; Coward, D. M.; Cowart, M. J.; Coyne, D. C.; Coyne, R.; E Creighton, J. D.; Creighton, T. D.; Cripe, J.; Crowder, S. G.; Cullen, T. J.; Cumming, A.; Cunningham, L.; Cuoco, E.; Dal Canton, T.; Danilishin, S. L.; D'Antonio, S.; Danzmann, K.; Dasgupta, A.; Da Silva Costa, C. F.; Dattilo, V.; Dave, I.; Davier, M.; Davies, G. S.; Davis, D.; Daw, E. J.; Day, B.; Day, R.; De, S.; DeBra, D.; Debreczeni, G.; Degallaix, J.; De Laurentis, M.; Deléglise, S.; Del Pozzo, W.; Denker, T.; Dent, T.; Dergachev, V.; De Rosa, R.; DeRosa, R. T.; DeSalvo, R.; Devenson, J.; Devine, R. C.; Dhurandhar, S.; Díaz, M. C.; Di Fiore, L.; Di Giovanni, M.; Di Girolamo, T.; Di Lieto, A.; Di Pace, S.; Di Palma, I.; Di Virgilio, A.; Doctor, Z.; Dolique, V.; Donovan, F.; Dooley, K. L.; Doravari, S.; Dorrington, I.; Douglas, R.; Dovale Álvarez, M.; Downes, T. P.; Drago, M.; Drever, R. W. P.; Driggers, J. C.; Du, Z.; Ducrot, M.; E Dwyer, S.; Edo, T. B.; Edwards, M. C.; Effler, A.; Eggenstein, H.-B.; Ehrens, P.; Eichholz, J.; Eikenberry, S. S.; Eisenstein, R. A.; Essick, R. C.; Etienne, Z.; Etzel, T.; Evans, M.; Evans, T. M.; Everett, R.; Factourovich, M.; Fafone, V.; Fair, H.; Fairhurst, S.; Fan, X.; Farinon, S.; Farr, B.; Farr, W. M.; Fauchon-Jones, E. J.; Favata, M.; Fays, M.; Fehrmann, H.; Fejer, M. M.; Fernández Galiana, A.; Ferrante, I.; Ferreira, E. C.; Ferrini, F.; Fidecaro, F.; Fiori, I.; Fiorucci, D.; Fisher, R. P.; Flaminio, R.; Fletcher, M.; Fong, H.; Forsyth, S. S.; Fournier, J.-D.; Frasca, S.; Frasconi, F.; Frei, Z.; Freise, A.; Frey, R.; Frey, V.; Fries, E. M.; Fritschel, P.; Frolov, V. V.; Fulda, P.; Fyffe, M.; Gabbard, H.; Gadre, B. U.; Gaebel, S. M.; Gair, J. R.; Gammaitoni, L.; Gaonkar, S. G.; Garufi, F.; Gaur, G.; Gayathri, V.; Gehrels, N.; Gemme, G.; Genin, E.; Gennai, A.; George, J.; Gergely, L.; Germain, V.; Ghonge, S.; Ghosh, Abhirup; Ghosh, Archisman; Ghosh, S.; Giaime, J. A.; Giardina, K. D.; Giazotto, A.; Gill, K.; Glaefke, A.; Goetz, E.; Goetz, R.; Gondan, L.; González, G.; Gonzalez Castro, J. M.; Gopakumar, A.; Gorodetsky, M. L.; E Gossan, S.; Gosselin, M.; Gouaty, R.; Grado, A.; Graef, C.; Granata, M.; Grant, A.; Gras, S.; Gray, C.; Greco, G.; Green, A. C.; Groot, P.; Grote, H.; Grunewald, S.; Guidi, G. M.; Guo, X.; Gupta, A.; Gupta, M. K.; E Gushwa, K.; Gustafson, E. K.; Gustafson, R.; Hacker, J. J.; Hall, B. R.; Hall, E. D.; Hammond, G.; Haney, M.; Hanke, M. M.; Hanks, J.; Hanna, C.; Hannam, M. D.; Hanson, J.; Hardwick, T.; Harms, J.; Harry, G. M.; Harry, I. W.; Hart, M. J.; Hartman, M. T.; Haster, C.-J.; Haughian, K.; Healy, J.; Heidmann, A.; Heintze, M. C.; Heitmann, H.; Hello, P.; Hemming, G.; Hendry, M.; Heng, I. S.; Hennig, J.; Henry, J.; Heptonstall, A. W.; Heurs, M.; Hild, S.; Hoak, D.; Hofman, D.; Holt, K.; E Holz, D.; Hopkins, P.; Hough, J.; Houston, E. A.; Howell, E. J.; Hu, Y. M.; Huerta, E. A.; Huet, D.; Hughey, B.; Husa, S.; Huttner, S. H.; Huynh-Dinh, T.; Indik, N.; Ingram, D. R.; Inta, R.; Isa, H. N.; Isac, J.-M.; Isi, M.; Isogai, T.; Iyer, B. R.; Izumi, K.; Jacqmin, T.; Jani, K.; Jaranowski, P.; Jawahar, S.; Jiménez-Forteza, F.; Johnson, W. W.; Jones, D. I.; Jones, R.; Jonker, R. J. G.; Ju, L.; Junker, J.; Kalaghatgi, C. V.; Kalogera, V.; Kandhasamy, S.; Kang, G.; Kanner, J. B.; Karki, S.; Karvinen, K. S.; Kasprzack, M.; Katsavounidis, E.; Katzman, W.; Kaufer, S.; Kaur, T.; Kawabe, K.; Kéfélian, F.; Keitel, D.; Kelley, D. B.; Kennedy, R.; Key, J. S.; Khalili, F. Y.; Khan, I.; Khan, S.; Khan, Z.; Khazanov, E. A.; Kijbunchoo, N.; Kim, Chunglee; Kim, J. C.; Kim, Whansun; Kim, W.; Kim, Y.-M.; Kimbrell, S. J.; King, E. J.; King, P. J.; Kirchhoff, R.; Kissel, J. S.; Klein, B.; Kleybolte, L.; Klimenko, S.; Koch, P.; Koehlenbeck, S. M.; Koley, S.; Kondrashov, V.; Kontos, A.; Korobko, M.; Korth, W. Z.; Kowalska, I.; Kozak, D. B.; Krämer, C.; Kringel, V.; Krishnan, B.; Królak, A.; Kuehn, G.; Kumar, P.; Kumar, R.; Kuo, L.; Kutynia, A.; Lackey, B. D.; Landry, M.; Lang, R. N.; Lange, J.; Lantz, B.; Lanza, R. K.; Lartaux-Vollard, A.; Lasky, P. D.; Laxen, M.; Lazzarini, A.; Lazzaro, C.; Leaci, P.; Leavey, S.; Lebigot, E. O.; Lee, C. H.; Lee, H. K.; Lee, H. M.; Lee, K.; Lehmann, J.; Lenon, A.; Leonardi, M.; Leong, J. R.; Leroy, N.; Letendre, N.; Levin, Y.; Li, T. G. F.; Libson, A.; Littenberg, T. B.; Liu, J.; Lockerbie, N. A.; Lombardi, A. L.; London, L. T.; E Lord, J.; Lorenzini, M.; Loriette, V.; Lormand, M.; Losurdo, G.; Lough, J. D.; Lovelace, G.; Lück, H.; Lundgren, A. P.; Lynch, R.; Ma, Y.; Macfoy, S.; Machenschalk, B.; MacInnis, M.; Macleod, D. M.; Magaña-Sandoval, F.; Majorana, E.; Maksimovic, I.; Malvezzi, V.; Man, N.; Mandic, V.; Mangano, V.; Mansell, G. L.; Manske, M.; Mantovani, M.; Marchesoni, F.; Marion, F.; Márka, S.; Márka, Z.; Markosyan, A. S.; Maros, E.; Martelli, F.; Martellini, L.; Martin, I. W.; Martynov, D. V.; Mason, K.; Masserot, A.; Massinger, T. J.; Masso-Reid, M.; Mastrogiovanni, S.; Matichard, F.; Matone, L.; Mavalvala, N.; Mazumder, N.; McCarthy, R.; E McClelland, D.; McCormick, S.; McGrath, C.; McGuire, S. C.; McIntyre, G.; McIver, J.; McManus, D. J.; McRae, T.; McWilliams, S. T.; Meacher, D.; Meadors, G. D.; Meidam, J.; Melatos, A.; Mendell, G.; Mendoza-Gandara, D.; Mercer, R. A.; Merilh, E. L.; Merzougui, M.; Meshkov, S.; Messenger, C.; Messick, C.; Metzdorff, R.; Meyers, P. M.; Mezzani, F.; Miao, H.; Michel, C.; Middleton, H.; E Mikhailov, E.; Milano, L.; Miller, A. L.; Miller, A.; Miller, B. B.; Miller, J.; Millhouse, M.; Minenkov, Y.; Ming, J.; Mirshekari, S.; Mishra, C.; Mitra, S.; Mitrofanov, V. P.; Mitselmakher, G.; Mittleman, R.; Moggi, A.; Mohan, M.; Mohapatra, S. R. P.; Montani, M.; Moore, B. C.; Moore, C. J.; Moraru, D.; Moreno, G.; Morriss, S. R.; Mours, B.; Mow-Lowry, C. M.; Mueller, G.; Muir, A. W.; Mukherjee, Arunava; Mukherjee, D.; Mukherjee, S.; Mukund, N.; Mullavey, A.; Munch, J.; Muniz, E. A. M.; Murray, P. G.; Mytidis, A.; Napier, K.; Nardecchia, I.; Naticchioni, L.; Nelemans, G.; Nelson, T. J. N.; Neri, M.; Nery, M.; Neunzert, A.; Newport, J. M.; Newton, G.; Nguyen, T. T.; Nielsen, A. B.; Nissanke, S.; Nitz, A.; Noack, A.; Nocera, F.; Nolting, D.; Normandin, M. E. N.; Nuttall, L. K.; Oberling, J.; Ochsner, E.; Oelker, E.; Ogin, G. H.; Oh, J. J.; Oh, S. H.; Ohme, F.; Oliver, M.; Oppermann, P.; Oram, Richard J.; O'Reilly, B.; O'Shaughnessy, R.; Ottaway, D. J.; Overmier, H.; Owen, B. J.; E Pace, A.; Page, J.; Pai, A.; Pai, S. A.; Palamos, J. R.; Palashov, O.; Palomba, C.; Pal-Singh, A.; Pan, H.; Pankow, C.; Pannarale, F.; Pant, B. C.; Paoletti, F.; Paoli, A.; Papa, M. A.; Paris, H. R.; Parker, W.; Pascucci, D.; Pasqualetti, A.; Passaquieti, R.; Passuello, D.; Patricelli, B.; Pearlstone, B. L.; Pedraza, M.; Pedurand, R.; Pekowsky, L.; Pele, A.; Penn, S.; Perez, C. J.; Perreca, A.; Perri, L. M.; Pfeiffer, H. P.; Phelps, M.; Piccinni, O. J.; Pichot, M.; Piergiovanni, F.; Pierro, V.; Pillant, G.; Pinard, L.; Pinto, I. M.; Pitkin, M.; Poe, M.; Poggiani, R.; Popolizio, P.; Post, A.; Powell, J.; Prasad, J.; Pratt, J. W. W.; Predoi, V.; Prestegard, T.; Prijatelj, M.; Principe, M.; Privitera, S.; Prodi, G. A.; Prokhorov, L. G.; Puncken, O.; Punturo, M.; Puppo, P.; Pürrer, M.; Qi, H.; Qin, J.; Qiu, S.; Quetschke, V.; Quintero, E. A.; Quitzow-James, R.; Raab, F. J.; Rabeling, D. S.; Radkins, H.; Raffai, P.; Raja, S.; Rajan, C.; Rakhmanov, M.; Rapagnani, P.; Raymond, V.; Razzano, M.; Re, V.; Read, J.; Regimbau, T.; Rei, L.; Reid, S.; Reitze, D. H.; Rew, H.; Reyes, S. D.; Rhoades, E.; Ricci, F.; Riles, K.; Rizzo, M.; Robertson, N. A.; Robie, R.; Robinet, F.; Rocchi, A.; Rolland, L.; Rollins, J. G.; Roma, V. J.; Romano, J. D.; Romano, R.; Romie, J. H.; Rosińska, D.; Rowan, S.; Rüdiger, A.; Ruggi, P.; Ryan, K.; Sachdev, S.; Sadecki, T.; Sadeghian, L.; Sakellariadou, M.; Salconi, L.; Saleem, M.; Salemi, F.; Samajdar, A.; Sammut, L.; Sampson, L. M.; Sanchez, E. J.; Sandberg, V.; Sanders, J. R.; Sassolas, B.; Sathyaprakash, B. S.; Saulson, P. R.; Sauter, O.; Savage, R. L.; Sawadsky, A.; Schale, P.; Scheuer, J.; Schmidt, E.; Schmidt, J.; Schmidt, P.; Schnabel, R.; Schofield, R. M. S.; Schönbeck, A.; Schreiber, E.; Schuette, D.; Schutz, B. F.; Schwalbe, S. G.; Scott, J.; Scott, S. M.; Sellers, D.; Sengupta, A. S.; Sentenac, D.; Sequino, V.; Sergeev, A.; Setyawati, Y.; Shaddock, D. A.; Shaffer, T. J.; Shahriar, M. S.; Shapiro, B.; Shawhan, P.; Sheperd, A.; Shoemaker, D. H.; Shoemaker, D. M.; Siellez, K.; Siemens, X.; Sieniawska, M.; Sigg, D.; Silva, A. D.; Singer, A.; Singer, L. P.; Singh, A.; Singh, R.; Singhal, A.; Sintes, A. M.; Slagmolen, B. J. J.; Smith, B.; Smith, J. R.; E Smith, R. J.; Son, E. J.; Sorazu, B.; Sorrentino, F.; Souradeep, T.; Spencer, A. P.; Srivastava, A. K.; Staley, A.; Steinke, M.; Steinlechner, J.; Steinlechner, S.; Steinmeyer, D.; Stephens, B. C.; Stevenson, S. P.; Stone, R.; Strain, K. A.; Straniero, N.; Stratta, G.; E Strigin, S.; Sturani, R.; Stuver, A. L.; Summerscales, T. Z.; Sun, L.; Sunil, S.; Sutton, P. J.; Swinkels, B. L.; Szczepańczyk, M. J.; Tacca, M.; Talukder, D.; Tanner, D. B.; Tápai, M.; Taracchini, A.; Taylor, R.; Theeg, T.; Thomas, E. G.; Thomas, M.; Thomas, P.; Thorne, K. A.; Thrane, E.; Tippens, T.; Tiwari, S.; Tiwari, V.; Tokmakov, K. V.; Toland, K.; Tomlinson, C.; Tonelli, M.; Tornasi, Z.; Torrie, C. I.; Töyrä, D.; Travasso, F.; Traylor, G.; Trifirò, D.; Trinastic, J.; Tringali, M. C.; Trozzo, L.; Tse, M.; Tso, R.; Turconi, M.; Tuyenbayev, D.; Ugolini, D.; Unnikrishnan, C. S.; Urban, A. L.; Usman, S. A.; Vahlbruch, H.; Vajente, G.; Valdes, G.; van Bakel, N.; van Beuzekom, M.; van den Brand, J. F. J.; Van Den Broeck, C.; Vander-Hyde, D. C.; van der Schaaf, L.; van Heijningen, J. V.; van Veggel, A. A.; Vardaro, M.; Varma, V.; Vass, S.; Vasúth, M.; Vecchio, A.; Vedovato, G.; Veitch, J.; Veitch, P. J.; Venkateswara, K.; Venugopalan, G.; Verkindt, D.; Vetrano, F.; Viceré, A.; Viets, A. D.; Vinciguerra, S.; Vine, D. J.; Vinet, J.-Y.; Vitale, S.; Vo, T.; Vocca, H.; Vorvick, C.; Voss, D. V.; Vousden, W. D.; Vyatchanin, S. P.; Wade, A. R.; E Wade, L.; Wade, M.; Walker, M.; Wallace, L.; Walsh, S.; Wang, G.; Wang, H.; Wang, M.; Wang, Y.; Ward, R. L.; Warner, J.; Was, M.; Watchi, J.; Weaver, B.; Wei, L.-W.; Weinert, M.; Weinstein, A. J.; Weiss, R.; Wen, L.; Weßels, P.; Westphal, T.; Wette, K.; Whelan, J. T.; Whiting, B. F.; Whittle, C.; Williams, D.; Williams, R. D.; Williamson, A. R.; Willis, J. L.; Willke, B.; Wimmer, M. H.; Winkler, W.; Wipf, C. C.; Wittel, H.; Woan, G.; Woehler, J.; Worden, J.; Wright, J. L.; Wu, D. S.; Wu, G.; Yam, W.; Yamamoto, H.; Yancey, C. C.; Yap, M. J.; Yu, Hang; Yu, Haocun; Yvert, M.; Zadrożny, A.; Zangrando, L.; Zanolin, M.; Zendri, J.-P.; Zevin, M.; Zhang, L.; Zhang, M.; Zhang, T.; Zhang, Y.; Zhao, C.; Zhou, M.; Zhou, Z.; Zhu, S. J.; Zhu, X. J.; E Zucker, M.; Zweizig, J.; LIGO Scientific Collaboration; Virgo Collaboration; Boyle, M.; Chu, T.; Hemberger, D.; Hinder, I.; E Kidder, L.; Ossokine, S.; Scheel, M.; Szilagyi, B.; Teukolsky, S.; Vano Vinuales, A.
2017-05-01
Parameter estimates of GW150914 were obtained using Bayesian inference, based on three semi-analytic waveform models for binary black hole coalescences. These waveform models differ from each other in their treatment of black hole spins, and all three models make some simplifying assumptions, notably to neglect sub-dominant waveform harmonic modes and orbital eccentricity. Furthermore, while the models are calibrated to agree with waveforms obtained by full numerical solutions of Einstein’s equations, any such calibration is accurate only to some non-zero tolerance and is limited by the accuracy of the underlying phenomenology, availability, quality, and parameter-space coverage of numerical simulations. This paper complements the original analyses of GW150914 with an investigation of the effects of possible systematic errors in the waveform models on estimates of its source parameters. To test for systematic errors we repeat the original Bayesian analysis on mock signals from numerical simulations of a series of binary configurations with parameters similar to those found for GW150914. Overall, we find no evidence for a systematic bias relative to the statistical error of the original parameter recovery of GW150914 due to modeling approximations or modeling inaccuracies. However, parameter biases are found to occur for some configurations disfavored by the data of GW150914: for binaries inclined edge-on to the detector over a small range of choices of polarization angles, and also for eccentricities greater than ˜0.05. For signals with higher signal-to-noise ratio than GW150914, or in other regions of the binary parameter space (lower masses, larger mass ratios, or higher spins), we expect that systematic errors in current waveform models may impact gravitational-wave measurements, making more accurate models desirable for future observations.
Prevalence of refractive errors in children in India: a systematic review.
Sheeladevi, Sethu; Seelam, Bharani; Nukella, Phanindra B; Modi, Aditi; Ali, Rahul; Keay, Lisa
2018-04-22
Uncorrected refractive error is an avoidable cause of visual impairment which affects children in India. The objective of this review is to estimate the prevalence of refractive errors in children ≤ 15 years of age. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were followed in this review. A detailed literature search was performed to include all population and school-based studies published from India between January 1990 and January 2017, using the Cochrane Library, Medline and Embase. The quality of the included studies was assessed based on a critical appraisal tool developed for systematic reviews of prevalence studies. Four population-based studies and eight school-based studies were included. The overall prevalence of refractive error per 100 children was 8.0 (CI: 7.4-8.1) and in schools it was 10.8 (CI: 10.5-11.2). The population-based prevalence of myopia, hyperopia (≥ +2.00 D) and astigmatism was 5.3 per cent, 4.0 per cent and 5.4 per cent, respectively. Combined refractive error and myopia alone were higher in urban areas compared to rural areas (odds ratio [OR]: 2.27 [CI: 2.09-2.45]) and (OR: 2.12 [CI: 1.79-2.50]), respectively. The prevalence of combined refractive errors and myopia alone in schools was higher among girls than boys (OR: 1.2 [CI: 1.1-1.3] and OR: 1.1 [CI: 1.1-1.2]), respectively. However, hyperopia was more prevalent among boys than girls in schools (OR: 2.1 [CI: 1.8-2.4]). Refractive error in children in India is a major public health problem and requires concerted efforts from various stakeholders including the health care workforce, education professionals and parents, to manage this issue. © 2018 Optometry Australia.
Iudici, Antonio; Salvini, Alessandro; Faccio, Elena; Castelnuovo, Gianluca
2015-01-01
According to the literature, psychological assessment in forensic contexts is one of the most controversial application areas for clinical psychology. This paper presents a review of systematic judgment errors in the forensic field. Forty-six psychological reports written by psychologists, court consultants, have been analyzed with content analysis to identify typical judgment errors related to the following areas: (a) distortions in the attribution of causality, (b) inferential errors, and (c) epistemological inconsistencies. Results indicated that systematic errors of judgment, usually referred also as “the man in the street,” are widely present in the forensic evaluations of specialist consultants. Clinical and practical implications are taken into account. This article could lead to significant benefits for clinical psychologists who want to deal with this sensitive issue and are interested in improving the quality of their contribution to the justice system. PMID:26648892
NASA Astrophysics Data System (ADS)
Pathiraja, S.; Anghileri, D.; Burlando, P.; Sharma, A.; Marshall, L.; Moradkhani, H.
2018-03-01
The global prevalence of rapid and extensive land use change necessitates hydrologic modelling methodologies capable of handling non-stationarity. This is particularly true in the context of Hydrologic Forecasting using Data Assimilation. Data Assimilation has been shown to dramatically improve forecast skill in hydrologic and meteorological applications, although such improvements are conditional on using bias-free observations and model simulations. A hydrologic model calibrated to a particular set of land cover conditions has the potential to produce biased simulations when the catchment is disturbed. This paper sheds new light on the impacts of bias or systematic errors in hydrologic data assimilation, in the context of forecasting in catchments with changing land surface conditions and a model calibrated to pre-change conditions. We posit that in such cases, the impact of systematic model errors on assimilation or forecast quality is dependent on the inherent prediction uncertainty that persists even in pre-change conditions. Through experiments on a range of catchments, we develop a conceptual relationship between total prediction uncertainty and the impacts of land cover changes on the hydrologic regime to demonstrate how forecast quality is affected when using state estimation Data Assimilation with no modifications to account for land cover changes. This work shows that systematic model errors as a result of changing or changed catchment conditions do not always necessitate adjustments to the modelling or assimilation methodology, for instance through re-calibration of the hydrologic model, time varying model parameters or revised offline/online bias estimation.
Errors in Viking Lander Atmospheric Profiles Discovered Using MOLA Topography
NASA Technical Reports Server (NTRS)
Withers, Paul; Lorenz, R. D.; Neumann, G. A.
2002-01-01
Each Viking lander measured a topographic profile during entry. Comparing to MOLA (Mars Orbiter Laser Altimeter), we find a vertical error of 1-2 km in the Viking trajectory. This introduces a systematic error of 10-20% in the Viking densities and pressures at a given altitude. Additional information is contained in the original extended abstract.
Medical errors arising from outsourcing laboratory and radiology services.
Chasin, Brian S; Elliott, Sean P; Klotz, Stephen A
2007-09-01
Document errors and the nuisance factor inherent in the informational exchange that occurs with the outsourcing of laboratory and radiology examinations. Three infectious diseases physicians at a tertiary care hospital recorded problems involving data transmitted by telephone or fax from outsource providers for 4 months. This included in- and outpatients, and those in transition from one status to another. Outsourcing laboratory and radiology examinations of insured outpatients is a common practice. Insurance companies determine which healthcare facility performs these tests based on contractual agreements with outsource providers. This leads to confusion and frustration for the doctor and patient alike, and occasionally, to medical error. The exchange of patient data involved in outsourcing is subject to systemic errors that do not allow of easy solution.
Liu, Shao-Hsien; Ulbricht, Christine M; Chrysanthopoulou, Stavroula A; Lapane, Kate L
2016-07-20
Causal mediation analysis is often used to understand the impact of variables along the causal pathway of an occurrence relation. How well studies apply and report the elements of causal mediation analysis remains unknown. We systematically reviewed epidemiological studies published in 2015 that employed causal mediation analysis to estimate direct and indirect effects of observed associations between an exposure on an outcome. We identified potential epidemiological studies through conducting a citation search within Web of Science and a keyword search within PubMed. Two reviewers independently screened studies for eligibility. For eligible studies, one reviewer performed data extraction, and a senior epidemiologist confirmed the extracted information. Empirical application and methodological details of the technique were extracted and summarized. Thirteen studies were eligible for data extraction. While the majority of studies reported and identified the effects of measures, most studies lacked sufficient details on the extent to which identifiability assumptions were satisfied. Although most studies addressed issues of unmeasured confounders either from empirical approaches or sensitivity analyses, the majority did not examine the potential bias arising from the measurement error of the mediator. Some studies allowed for exposure-mediator interaction and only a few presented results from models both with and without interactions. Power calculations were scarce. Reporting of causal mediation analysis is varied and suboptimal. Given that the application of causal mediation analysis will likely continue to increase, developing standards of reporting of causal mediation analysis in epidemiological research would be prudent.
Improving travel information products via robust estimation techniques : final report, March 2009.
DOT National Transportation Integrated Search
2009-03-01
Traffic-monitoring systems, such as those using loop detectors, are prone to coverage gaps, arising from sensor noise, processing errors and : transmission problems. Such gaps adversely affect the accuracy of Advanced Traveler Information Systems. Th...
Mellado-Ortega, Elena; Zabalgogeazcoa, Iñigo; Vázquez de Aldana, Beatriz R; Arellano, Juan B
2017-02-15
Oxygen radical absorbance capacity (ORAC) assay in 96-well multi-detection plate readers is a rapid method to determine total antioxidant capacity (TAC) in biological samples. A disadvantage of this method is that the antioxidant inhibition reaction does not start in all of the 96 wells at the same time due to technical limitations when dispensing the free radical-generating azo initiator 2,2'-azobis (2-methyl-propanimidamide) dihydrochloride (AAPH). The time delay between wells yields a systematic error that causes statistically significant differences in TAC determination of antioxidant solutions depending on their plate position. We propose two alternative solutions to avoid this AAPH-dependent error in ORAC assays. Copyright © 2016 Elsevier Inc. All rights reserved.
Accuracy Improvement of Multi-Axis Systems Based on Laser Correction of Volumetric Geometric Errors
NASA Astrophysics Data System (ADS)
Teleshevsky, V. I.; Sokolov, V. A.; Pimushkin, Ya I.
2018-04-01
The article describes a volumetric geometric errors correction method for CNC- controlled multi-axis systems (machine-tools, CMMs etc.). The Kalman’s concept of “Control and Observation” is used. A versatile multi-function laser interferometer is used as Observer in order to measure machine’s error functions. A systematic error map of machine’s workspace is produced based on error functions measurements. The error map results into error correction strategy. The article proposes a new method of error correction strategy forming. The method is based on error distribution within machine’s workspace and a CNC-program postprocessor. The postprocessor provides minimal error values within maximal workspace zone. The results are confirmed by error correction of precision CNC machine-tools.
Counteracting structural errors in ensemble forecast of influenza outbreaks.
Pei, Sen; Shaman, Jeffrey
2017-10-13
For influenza forecasts generated using dynamical models, forecast inaccuracy is partly attributable to the nonlinear growth of error. As a consequence, quantification of the nonlinear error structure in current forecast models is needed so that this growth can be corrected and forecast skill improved. Here, we inspect the error growth of a compartmental influenza model and find that a robust error structure arises naturally from the nonlinear model dynamics. By counteracting these structural errors, diagnosed using error breeding, we develop a new forecast approach that combines dynamical error correction and statistical filtering techniques. In retrospective forecasts of historical influenza outbreaks for 95 US cities from 2003 to 2014, overall forecast accuracy for outbreak peak timing, peak intensity and attack rate, are substantially improved for predicted lead times up to 10 weeks. This error growth correction method can be generalized to improve the forecast accuracy of other infectious disease dynamical models.Inaccuracy of influenza forecasts based on dynamical models is partly due to nonlinear error growth. Here the authors address the error structure of a compartmental influenza model, and develop a new improved forecast approach combining dynamical error correction and statistical filtering techniques.
Knobel, Mark; Finkbeiner, Matthew; Caramazza, Alfonso
2008-03-01
The effect of lexical frequency on language-processing tasks is exceptionally reliable. For example, pictures with higher frequency names are named faster and more accurately than those with lower frequency names. Experiments with normal participants and patients strongly suggest that this production effect arises at the level of lexical access. Further work has suggested that within lexical access this effect arises at the level of lexical representations. Here we present patient E.C. who shows an effect of lexical frequency on his nonword error rate. The best explanation of his performance is that there is an additional locus of frequency at the interface of lexical and segmental representational levels. We confirm this hypothesis by showing that only computational models with frequency at this new locus can produce a similar error pattern to that of patient E.C. Finally, in an analysis of a large group of Italian patients, we show that there exist patients who replicate E.C.'s pattern of results and others who show the complementary pattern of frequency effects on semantic error rates. Our results combined with previous findings suggest that frequency plays a role throughout the process of lexical access.
[Improving blood safety: errors management in transfusion medicine].
Bujandrić, Nevenka; Grujić, Jasmina; Krga-Milanović, Mirjana
2014-01-01
The concept of blood safety includes the entire transfusion chain starting with the collection of blood from the blood donor, and ending with blood transfusion to the patient. The concept involves quality management system as the systematic monitoring of adverse reactions and incidents regarding the blood donor or patient. Monitoring of near-miss errors show the critical points in the working process and increase transfusion safety. The aim of the study was to present the analysis results of adverse and unexpected events in transfusion practice with a potential risk to the health of blood donors and patients. One-year retrospective study was based on the collection, analysis and interpretation of written reports on medical errors in the Blood Transfusion Institute of Vojvodina. Errors were distributed according to the type, frequency and part of the working process where they occurred. Possible causes and corrective actions were described for each error. The study showed that there were not errors with potential health consequences for the blood donor/patient. Errors with potentially damaging consequences for patients were detected throughout the entire transfusion chain. Most of the errors were identified in the preanalytical phase. The human factor was responsible for the largest number of errors. Error reporting system has an important role in the error management and the reduction of transfusion-related risk of adverse events and incidents. The ongoing analysis reveals the strengths and weaknesses of the entire process and indicates the necessary changes. Errors in transfusion medicine can be avoided in a large percentage and prevention is cost-effective, systematic and applicable.
Improvements in GRACE Gravity Field Determination through Stochastic Observation Modeling
NASA Astrophysics Data System (ADS)
McCullough, C.; Bettadpur, S. V.
2016-12-01
Current unconstrained Release 05 GRACE gravity field solutions from the Center for Space Research (CSR RL05) assume random observation errors following an independent multivariate Gaussian distribution. This modeling of observations, a simplifying assumption, fails to account for long period, correlated errors arising from inadequacies in the background force models. Fully modeling the errors inherent in the observation equations, through the use of a full observation covariance (modeling colored noise), enables optimal combination of GPS and inter-satellite range-rate data and obviates the need for estimating kinematic empirical parameters during the solution process. Most importantly, fully modeling the observation errors drastically improves formal error estimates of the spherical harmonic coefficients, potentially enabling improved uncertainty quantification of scientific results derived from GRACE and optimizing combinations of GRACE with independent data sets and a priori constraints.
Efficient Variational Quantum Simulator Incorporating Active Error Minimization
NASA Astrophysics Data System (ADS)
Li, Ying; Benjamin, Simon C.
2017-04-01
One of the key applications for quantum computers will be the simulation of other quantum systems that arise in chemistry, materials science, etc., in order to accelerate the process of discovery. It is important to ask the following question: Can this simulation be achieved using near-future quantum processors, of modest size and under imperfect control, or must it await the more distant era of large-scale fault-tolerant quantum computing? Here, we propose a variational method involving closely integrated classical and quantum coprocessors. We presume that all operations in the quantum coprocessor are prone to error. The impact of such errors is minimized by boosting them artificially and then extrapolating to the zero-error case. In comparison to a more conventional optimized Trotterization technique, we find that our protocol is efficient and appears to be fundamentally more robust against error accumulation.
NASA Astrophysics Data System (ADS)
Debchoudhury, Shantanab; Earle, Gregory
2017-04-01
Retarding Potential Analyzers (RPA) have a rich flight heritage. Standard curve-fitting analysis techniques exist that can infer state variables in the ionospheric plasma environment from RPA data, but the estimation process is prone to errors arising from a number of sources. Previous work has focused on the effects of grid geometry on uncertainties in estimation; however, no prior study has quantified the estimation errors due to additive noise. In this study, we characterize the errors in estimation of thermal plasma parameters by adding noise to the simulated data derived from the existing ionospheric models. We concentrate on low-altitude, mid-inclination orbits since a number of nano-satellite missions are focused on this region of the ionosphere. The errors are quantified and cross-correlated for varying geomagnetic conditions.
Hsu, Yi-Fang; Vincent, Romain; Waszak, Florian
2015-08-27
Recent research suggested a link between the prediction mechanism and depressive symptoms. While healthy people tend to maintain unrealistic optimism in the face of reality challenging their beliefs, depressed people show systematic pessimism. However, it remains unclear at which stage these individual differences in optimism/pessimism arise in the brain. In the current study we designed a simple gambling task with two difficulty levels, the easy game and the hard game. Participants were required to press one of four keys to gain a bonus signalled by a sinusoidal tone. For three of the four keys, the probability of getting a large bonus was 80% in the easy game and 8% in the hard game. In both games, the fourth key, randomly determined in each trial, yielded a large bonus with a probability of 100%. This arrangement allowed us to observe less/more depressed participants׳ optimistic/pessimistic expectations about hitting the key that guarantees a large bonus. The opposite expectation patterns of less/more depressed participants were reflected on the N1 amplitude. Meanwhile, all participants were well aware of the true probability of obtaining certain bonus in each game as reflected on the P3 amplitude. The results suggest that the subjective system (tracking subjective beliefs) and the objective system (tracking objective evidence) are dissociable in the human brain, with the former feeding information into sensory areas and the latter representing prediction errors on a higher level. Moreover, individual differences arise from variability in the former rather than the latter. Copyright © 2015 Elsevier B.V. All rights reserved.
Miller, Marlene R; Robinson, Karen A; Lubomski, Lisa H; Rinke, Michael L; Pronovost, Peter J
2007-01-01
Background Although children are at the greatest risk for medication errors, little is known about the overall epidemiology of these errors, where the gaps are in our knowledge, and to what extent national medication error reduction strategies focus on children. Objective To synthesise peer reviewed knowledge on children's medication errors and on recommendations to improve paediatric medication safety by a systematic literature review. Data sources PubMed, Embase and Cinahl from 1 January 2000 to 30 April 2005, and 11 national entities that have disseminated recommendations to improve medication safety. Study selection Inclusion criteria were peer reviewed original data in English language. Studies that did not separately report paediatric data were excluded. Data extraction Two reviewers screened articles for eligibility and for data extraction, and screened all national medication error reduction strategies for relevance to children. Data synthesis From 358 articles identified, 31 were included for data extraction. The definition of medication error was non‐uniform across the studies. Dispensing and administering errors were the most poorly and non‐uniformly evaluated. Overall, the distributional epidemiological estimates of the relative percentages of paediatric error types were: prescribing 3–37%, dispensing 5–58%, administering 72–75%, and documentation 17–21%. 26 unique recommendations for strategies to reduce medication errors were identified; none were based on paediatric evidence. Conclusions Medication errors occur across the entire spectrum of prescribing, dispensing, and administering, are common, and have a myriad of non‐evidence based potential reduction strategies. Further research in this area needs a firmer standardisation for items such as dose ranges and definitions of medication errors, broader scope beyond inpatient prescribing errors, and prioritisation of implementation of medication error reduction strategies. PMID:17403758
Particle Tracking on the BNL Relativistic Heavy Ion Collider
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dell, G. F.
1986-08-07
Tracking studies including the effects of random multipole errors as well as the effects of random and systematic multipole errors have been made for RHIC. Initial results for operating at an off diagonal working point are discussed.
Tooth-meshing-harmonic static-transmission-error amplitudes of helical gears
NASA Astrophysics Data System (ADS)
Mark, William D.
2018-01-01
The static transmission errors of meshing gear pairs arise from deviations of loaded tooth working surfaces from equispaced perfect involute surfaces. Such deviations consist of tooth-pair elastic deformations and geometric deviations (modifications) of tooth working surfaces. To a very good approximation, the static-transmission-error tooth-meshing-harmonic amplitudes of helical gears are herein expressed by superposition of Fourier transforms of the quantities: (1) the combination of tooth-pair elastic deformations and geometric tooth-pair modifications and (2) fractional mesh-stiffness fluctuations, each quantity (1) and (2) expressed as a function of involute "roll distance." Normalization of the total roll-distance single-tooth contact span to unity allows tooth-meshing-harmonic amplitudes to be computed for different shapes of the above-described quantities (1) and (2). Tooth-meshing harmonics p = 1, 2, … are shown to occur at Fourier-transform harmonic values of Qp, p = 1, 2, …, where Q is the actual (total) contact ratio, thereby verifying its importance in minimizing transmission-error tooth-meshing-harmonic amplitudes. Two individual shapes and two series of shapes of the quantities (1) and (2) are chosen to illustrate a wide variety of shapes. In most cases representative of helical gears, tooth-meshing-harmonic values p = 1, 2, … are shown to occur in Fourier-transform harmonic regions governed by discontinuities arising from tooth-pair-contact initiation and termination, thereby showing the importance of minimizing such discontinuities. Plots and analytical expressions for all such Fourier transforms are presented, thereby illustrating the effects of various types of tooth-working-surface modifications and tooth-pair stiffnesses on transmission-error generation.
Verhoeven, Karolien; Weltens, Caroline; Van den Heuvel, Frank
2015-01-01
Quantification of the setup errors is vital to define appropriate setup margins preventing geographical misses. The no‐action–level (NAL) correction protocol reduces the systematic setup errors and, hence, the setup margins. The manual entry of the setup corrections in the record‐and‐verify software, however, increases the susceptibility of the NAL protocol to human errors. Moreover, the impact of the skin mobility on the anteroposterior patient setup reproducibility in whole‐breast radiotherapy (WBRT) is unknown. In this study, we therefore investigated the potential of fixed vertical couch position‐based patient setup in WBRT. The possibility to introduce a threshold for correction of the systematic setup errors was also explored. We measured the anteroposterior, mediolateral, and superior–inferior setup errors during fractions 1–12 and weekly thereafter with tangential angled single modality paired imaging. These setup data were used to simulate the residual setup errors of the NAL protocol, the fixed vertical couch position protocol, and the fixed‐action–level protocol with different correction thresholds. Population statistics of the setup errors of 20 breast cancer patients and 20 breast cancer patients with additional regional lymph node (LN) irradiation were calculated to determine the setup margins of each off‐line correction protocol. Our data showed the potential of the fixed vertical couch position protocol to restrict the systematic and random anteroposterior residual setup errors to 1.8 mm and 2.2 mm, respectively. Compared to the NAL protocol, a correction threshold of 2.5 mm reduced the frequency of mediolateral and superior–inferior setup corrections with 40% and 63%, respectively. The implementation of the correction threshold did not deteriorate the accuracy of the off‐line setup correction compared to the NAL protocol. The combination of the fixed vertical couch position protocol, for correction of the anteroposterior setup error, and the fixed‐action–level protocol with 2.5 mm correction threshold, for correction of the mediolateral and the superior–inferior setup errors, was proved to provide adequate and comparable patient setup accuracy in WBRT and WBRT with additional LN irradiation. PACS numbers: 87.53.Kn, 87.57.‐s
The most common mistakes on dermatoscopy of melanocytic lesions
Kamińska-Winciorek, Grażyna
2015-01-01
Dermatoscopy is a method of in vivo evaluation of the structures within the epidermis and dermis. Currently, it may be the most precise pre-surgical method of diagnosing melanocytic lesions. Diagnostic errors may result in unnecessary removal of benign lesions or what is even worse, they can cause early and very early melanomas to be overlooked. Errors in assessment of dermatoscopy can be divided into those arising from failure to maintain proper test procedures (procedural and technical errors) and knowledge based mistakes related to the lack of sufficient familiarity and experience in dermatoscopy. The article discusses the most common mistakes made by beginner or inexperienced dermatoscopists. PMID:25821425
NASA Technical Reports Server (NTRS)
2008-01-01
When we began our study we sought to answer five fundamental implementation questions: 1) can foregrounds be measured and subtracted to a sufficiently low level?; 2) can systematic errors be controlled?; 3) can we develop optics with sufficiently large throughput, low polarization, and frequency coverage from 30 to 300 GHz?; 4) is there a technical path to realizing the sensitivity and systematic error requirements?; and 5) what are the specific mission architecture parameters, including cost? Detailed answers to these questions are contained in this report.
NASA Astrophysics Data System (ADS)
Wang, Yang; Beirle, Steffen; Hendrick, Francois; Hilboll, Andreas; Jin, Junli; Kyuberis, Aleksandra A.; Lampel, Johannes; Li, Ang; Luo, Yuhan; Lodi, Lorenzo; Ma, Jianzhong; Navarro, Monica; Ortega, Ivan; Peters, Enno; Polyansky, Oleg L.; Remmers, Julia; Richter, Andreas; Puentedura, Olga; Van Roozendael, Michel; Seyler, André; Tennyson, Jonathan; Volkamer, Rainer; Xie, Pinhua; Zobov, Nikolai F.; Wagner, Thomas
2017-10-01
In order to promote the development of the passive DOAS technique the Multi Axis DOAS - Comparison campaign for Aerosols and Trace gases (MAD-CAT) was held at the Max Planck Institute for Chemistry in Mainz, Germany, from June to October 2013. Here, we systematically compare the differential slant column densities (dSCDs) of nitrous acid (HONO) derived from measurements of seven different instruments. We also compare the tropospheric difference of SCDs (delta SCD) of HONO, namely the difference of the SCDs for the non-zenith observations and the zenith observation of the same elevation sequence. Different research groups analysed the spectra from their own instruments using their individual fit software. All the fit errors of HONO dSCDs from the instruments with cooled large-size detectors are mostly in the range of 0.1 to 0.3 × 1015 molecules cm-2 for an integration time of 1 min. The fit error for the mini MAX-DOAS is around 0.7 × 1015 molecules cm-2. Although the HONO delta SCDs are normally smaller than 6 × 1015 molecules cm-2, consistent time series of HONO delta SCDs are retrieved from the measurements of different instruments. Both fits with a sequential Fraunhofer reference spectrum (FRS) and a daily noon FRS lead to similar consistency. Apart from the mini-MAX-DOAS, the systematic absolute differences of HONO delta SCDs between the instruments are smaller than 0.63 × 1015 molecules cm-2. The correlation coefficients are higher than 0.7 and the slopes of linear regressions deviate from unity by less than 16 % for the elevation angle of 1°. The correlations decrease with an increase in elevation angle. All the participants also analysed synthetic spectra using the same baseline DOAS settings to evaluate the systematic errors of HONO results from their respective fit programs. In general the errors are smaller than 0.3 × 1015 molecules cm-2, which is about half of the systematic difference between the real measurements.The differences of HONO delta SCDs retrieved in the selected three spectral ranges 335-361, 335-373 and 335-390 nm are considerable (up to 0.57 × 1015 molecules cm-2) for both real measurements and synthetic spectra. We performed sensitivity studies to quantify the dominant systematic error sources and to find a recommended DOAS setting in the three spectral ranges. The results show that water vapour absorption, temperature and wavelength dependence of O4 absorption, temperature dependence of Ring spectrum, and polynomial and intensity offset correction all together dominate the systematic errors. We recommend a fit range of 335-373 nm for HONO retrievals. In such fit range the overall systematic uncertainty is about 0.87 × 1015 molecules cm-2, much smaller than those in the other two ranges. The typical random uncertainty is estimated to be about 0.16 × 1015 molecules cm-2, which is only 25 % of the total systematic uncertainty for most of the instruments in the MAD-CAT campaign. In summary for most of the MAX-DOAS instruments for elevation angle below 5°, half daytime measurements (usually in the morning) of HONO delta SCD can be over the detection limit of 0.2 × 1015 molecules cm-2 with an uncertainty of ˜ 0.9 × 1015 molecules cm-2.
ERIC Educational Resources Information Center
Choe, Wook Kyung
2013-01-01
The current dissertation represents one of the first systematic studies of the distribution of speech errors within supralexical prosodic units. Four experiments were conducted to gain insight into the specific role of these units in speech planning and production. The first experiment focused on errors in adult English. These were found to be…
A geometric model for initial orientation errors in pigeon navigation.
Postlethwaite, Claire M; Walker, Michael M
2011-01-21
All mobile animals respond to gradients in signals in their environment, such as light, sound, odours and magnetic and electric fields, but it remains controversial how they might use these signals to navigate over long distances. The Earth's surface is essentially two-dimensional, so two stimuli are needed to act as coordinates for navigation. However, no environmental fields are known to be simple enough to act as perpendicular coordinates on a two-dimensional grid. Here, we propose a model for navigation in which we assume that an animal has a simplified 'cognitive map' in which environmental stimuli act as perpendicular coordinates. We then investigate how systematic deviation of the contour lines of the environmental signals from a simple orthogonal arrangement can cause errors in position determination and lead to systematic patterns of directional errors in initial homing directions taken by pigeons. The model reproduces patterns of initial orientation errors seen in previously collected data from homing pigeons, predicts that errors should increase with distance from the loft, and provides a basis for efforts to identify further sources of orientation errors made by homing pigeons. Copyright © 2010 Elsevier Ltd. All rights reserved.
Horizon sensors attitude errors simulation for the Brazilian Remote Sensing Satellite
NASA Astrophysics Data System (ADS)
Vicente de Brum, Antonio Gil; Ricci, Mario Cesar
Remote sensing, meteorological and other types of satellites require an increasingly better Earth related positioning. From the past experience it is well known that the thermal horizon in the 15 micrometer band provides conditions of determining the local vertical at any time. This detection is done by horizon sensors which are accurate instruments for Earth referred attitude sensing and control whose performance is limited by systematic and random errors amounting about 0.5 deg. Using the computer programs OBLATE, SEASON, ELECTRO and MISALIGN, developed at INPE to simulate four distinct facets of conical scanning horizon sensors, attitude errors are obtained for the Brazilian Remote Sensing Satellite (the first one, SSR-1, is scheduled to fly in 1996). These errors are due to the oblate shape of the Earth, seasonal and latitudinal variations of the 15 micrometer infrared radiation, electronic processing time delay and misalignment of sensor axis. The sensor related attitude errors are thus properly quantified in this work and will, together with other systematic errors (for instance, ambient temperature variation) take part in the pre-launch analysis of the Brazilian Remote Sensing Satellite, with respect to the horizon sensor performance.
Interplanetary Trajectories, Encke Method (ITEM)
NASA Technical Reports Server (NTRS)
Whitlock, F. H.; Wolfe, H.; Lefton, L.; Levine, N.
1972-01-01
Modified program has been developed using improved variation of Encke method which avoids accumulation of round-off errors and avoids numerical ambiguities arising from near-circular orbits of low inclination. Variety of interplanetary trajectory problems can be computed with maximum accuracy and efficiency.
Systematic Error in Leaf Water Potential Measurements with a Thermocouple Psychrometer.
Rawlins, S L
1964-10-30
To allow for the error in measurement of water potentials in leaves, introduced by the presence of a water droplet in the chamber of the psychrometer, a correction must be made for the permeability of the leaf.
Heneka, Nicole; Shaw, Tim; Rowett, Debra; Phillips, Jane L
2016-06-01
Opioids are the primary pharmacological treatment for cancer pain and, in the palliative care setting, are routinely used to manage symptoms at the end of life. Opioids are one of the most frequently reported drug classes in medication errors causing patient harm. Despite their widespread use, little is known about the incidence and impact of opioid medication errors in oncology and palliative care settings. To determine the incidence, types and impact of reported opioid medication errors in adult oncology and palliative care patient settings. A systematic review. Five electronic databases and the grey literature were searched from 1980 to August 2014. Empirical studies published in English, reporting data on opioid medication error incidence, types or patient impact, within adult oncology and/or palliative care services, were included. Popay's narrative synthesis approach was used to analyse data. Five empirical studies were included in this review. Opioid error incidence rate was difficult to ascertain as each study focussed on a single narrow area of error. The predominant error type related to deviation from opioid prescribing guidelines, such as incorrect dosing intervals. None of the included studies reported the degree of patient harm resulting from opioid errors. This review has highlighted the paucity of the literature examining opioid error incidence, types and patient impact in adult oncology and palliative care settings. Defining, identifying and quantifying error reporting practices for these populations should be an essential component of future oncology and palliative care quality and safety initiatives. © The Author(s) 2015.
Loran digital phase-locked loop and RF front-end system error analysis
NASA Technical Reports Server (NTRS)
Mccall, D. L.
1979-01-01
An analysis of the system performance of the digital phase locked loops (DPLL) and RF front end that are implemented in the MINI-L4 Loran receiver is presented. Three of the four experiments deal with the performance of the digital phase locked loops. The other experiment deals with the RF front end and DPLL system error which arise in the front end due to poor signal to noise ratios. The ability of the DPLLs to track the offsets is studied.
Systematic review of the evidence for Trails B cut-off scores in assessing fitness-to-drive.
Roy, Mononita; Molnar, Frank
2013-01-01
Fitness-to-drive guidelines recommend employing the Trail Making B Test (a.k.a. Trails B), but do not provide guidance regarding cut-off scores. There is ongoing debate regarding the optimal cut-off score on the Trails B test. The objective of this study was to address this controversy by systematically reviewing the evidence for specific Trails B cut-off scores (e.g., cut-offs in both time to completion and number of errors) with respect to fitness-to-drive. Systematic review of all prospective cohort, retrospective cohort, case-control, correlation, and cross-sectional studies reporting the ability of the Trails B to predict driving safety that were published in English-language, peer-reviewed journals. Forty-seven articles were reviewed. None of the articles justified sample sizes via formal calculations. Cut-off scores reported based on research include: 90 seconds, 133 seconds, 147 seconds, 180 seconds, and < 3 errors. There is support for the previously published Trails B cut-offs of 3 minutes or 3 errors (the '3 or 3 rule'). Major methodological limitations of this body of research were uncovered including (1) lack of justification of sample size leaving studies open to Type II error (i.e., false negative findings), and (2) excessive focus on associations rather than clinically useful cut-off scores.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kirchhoff, William H.
2012-09-15
The extended logistic function provides a physically reasonable description of interfaces such as depth profiles or line scans of surface topological or compositional features. It describes these interfaces with the minimum number of parameters, namely, position, width, and asymmetry. Logistic Function Profile Fit (LFPF) is a robust, least-squares fitting program in which the nonlinear extended logistic function is linearized by a Taylor series expansion (equivalent to a Newton-Raphson approach) with no apparent introduction of bias in the analysis. The program provides reliable confidence limits for the parameters when systematic errors are minimal and provides a display of the residuals frommore » the fit for the detection of systematic errors. The program will aid researchers in applying ASTM E1636-10, 'Standard practice for analytically describing sputter-depth-profile and linescan-profile data by an extended logistic function,' and may also prove useful in applying ISO 18516: 2006, 'Surface chemical analysis-Auger electron spectroscopy and x-ray photoelectron spectroscopy-determination of lateral resolution.' Examples are given of LFPF fits to a secondary ion mass spectrometry depth profile, an Auger surface line scan, and synthetic data generated to exhibit known systematic errors for examining the significance of such errors to the extrapolation of partial profiles.« less
The effect of rainfall measurement uncertainties on rainfall-runoff processes modelling.
Stransky, D; Bares, V; Fatka, P
2007-01-01
Rainfall data are a crucial input for various tasks concerning the wet weather period. Nevertheless, their measurement is affected by random and systematic errors that cause an underestimation of the rainfall volume. Therefore, the general objective of the presented work was to assess the credibility of measured rainfall data and to evaluate the effect of measurement errors on urban drainage modelling tasks. Within the project, the methodology of the tipping bucket rain gauge (TBR) was defined and assessed in terms of uncertainty analysis. A set of 18 TBRs was calibrated and the results were compared to the previous calibration. This enables us to evaluate the ageing of TBRs. A propagation of calibration and other systematic errors through the rainfall-runoff model was performed on experimental catchment. It was found that the TBR calibration is important mainly for tasks connected with the assessment of peak values and high flow durations. The omission of calibration leads to up to 30% underestimation and the effect of other systematic errors can add a further 15%. The TBR calibration should be done every two years in order to catch up the ageing of TBR mechanics. Further, the authors recommend to adjust the dynamic test duration proportionally to generated rainfall intensity.
Chiral extrapolation of the leading hadronic contribution to the muon anomalous magnetic moment
NASA Astrophysics Data System (ADS)
Golterman, Maarten; Maltman, Kim; Peris, Santiago
2017-04-01
A lattice computation of the leading-order hadronic contribution to the muon anomalous magnetic moment can potentially help reduce the error on the Standard Model prediction for this quantity, if sufficient control of all systematic errors affecting such a computation can be achieved. One of these systematic errors is that associated with the extrapolation to the physical pion mass from values on the lattice larger than the physical pion mass. We investigate this extrapolation assuming lattice pion masses in the range of 200 to 400 MeV with the help of two-loop chiral perturbation theory, and we find that such an extrapolation is unlikely to lead to control of this systematic error at the 1% level. This remains true even if various tricks to improve the reliability of the chiral extrapolation employed in the literature are taken into account. In addition, while chiral perturbation theory also predicts the dependence on the pion mass of the leading-order hadronic contribution to the muon anomalous magnetic moment as the chiral limit is approached, this prediction turns out to be of no practical use because the physical pion mass is larger than the muon mass that sets the scale for the onset of this behavior.
Quotation accuracy in medical journal articles-a systematic review and meta-analysis.
Jergas, Hannah; Baethge, Christopher
2015-01-01
Background. Quotations and references are an indispensable element of scientific communication. They should support what authors claim or provide important background information for readers. Studies indicate, however, that quotations not serving their purpose-quotation errors-may be prevalent. Methods. We carried out a systematic review, meta-analysis and meta-regression of quotation errors, taking account of differences between studies in error ascertainment. Results. Out of 559 studies screened we included 28 in the main analysis, and estimated major, minor and total quotation error rates of 11,9%, 95% CI [8.4, 16.6] 11.5% [8.3, 15.7], and 25.4% [19.5, 32.4]. While heterogeneity was substantial, even the lowest estimate of total quotation errors was considerable (6.7%). Indirect references accounted for less than one sixth of all quotation problems. The findings remained robust in a number of sensitivity and subgroup analyses (including risk of bias analysis) and in meta-regression. There was no indication of publication bias. Conclusions. Readers of medical journal articles should be aware of the fact that quotation errors are common. Measures against quotation errors include spot checks by editors and reviewers, correct placement of citations in the text, and declarations by authors that they have checked cited material. Future research should elucidate if and to what degree quotation errors are detrimental to scientific progress.
Outcomes of a Failure Mode and Effects Analysis for medication errors in pediatric anesthesia.
Martin, Lizabeth D; Grigg, Eliot B; Verma, Shilpa; Latham, Gregory J; Rampersad, Sally E; Martin, Lynn D
2017-06-01
The Institute of Medicine has called for development of strategies to prevent medication errors, which are one important cause of preventable harm. Although the field of anesthesiology is considered a leader in patient safety, recent data suggest high medication error rates in anesthesia practice. Unfortunately, few error prevention strategies for anesthesia providers have been implemented. Using Toyota Production System quality improvement methodology, a multidisciplinary team observed 133 h of medication practice in the operating room at a tertiary care freestanding children's hospital. A failure mode and effects analysis was conducted to systematically deconstruct and evaluate each medication handling process step and score possible failure modes to quantify areas of risk. A bundle of five targeted countermeasures were identified and implemented over 12 months. Improvements in syringe labeling (73 to 96%), standardization of medication organization in the anesthesia workspace (0 to 100%), and two-provider infusion checks (23 to 59%) were observed. Medication error reporting improved during the project and was subsequently maintained. After intervention, the median medication error rate decreased from 1.56 to 0.95 per 1000 anesthetics. The frequency of medication error harm events reaching the patient also decreased. Systematic evaluation and standardization of medication handling processes by anesthesia providers in the operating room can decrease medication errors and improve patient safety. © 2017 John Wiley & Sons Ltd.
De-biasing the dynamic mode decomposition for applied Koopman spectral analysis of noisy datasets
NASA Astrophysics Data System (ADS)
Hemati, Maziar S.; Rowley, Clarence W.; Deem, Eric A.; Cattafesta, Louis N.
2017-08-01
The dynamic mode decomposition (DMD)—a popular method for performing data-driven Koopman spectral analysis—has gained increased popularity for extracting dynamically meaningful spatiotemporal descriptions of fluid flows from snapshot measurements. Often times, DMD descriptions can be used for predictive purposes as well, which enables informed decision-making based on DMD model forecasts. Despite its widespread use and utility, DMD can fail to yield accurate dynamical descriptions when the measured snapshot data are imprecise due to, e.g., sensor noise. Here, we express DMD as a two-stage algorithm in order to isolate a source of systematic error. We show that DMD's first stage, a subspace projection step, systematically introduces bias errors by processing snapshots asymmetrically. To remove this systematic error, we propose utilizing an augmented snapshot matrix in a subspace projection step, as in problems of total least-squares, in order to account for the error present in all snapshots. The resulting unbiased and noise-aware total DMD (TDMD) formulation reduces to standard DMD in the absence of snapshot errors, while the two-stage perspective generalizes the de-biasing framework to other related methods as well. TDMD's performance is demonstrated in numerical and experimental fluids examples. In particular, in the analysis of time-resolved particle image velocimetry data for a separated flow, TDMD outperforms standard DMD by providing dynamical interpretations that are consistent with alternative analysis techniques. Further, TDMD extracts modes that reveal detailed spatial structures missed by standard DMD.
Hinton-Bayre, Anton D
2011-02-01
There is an ongoing debate over the preferred method(s) for determining the reliable change (RC) in individual scores over time. In the present paper, specificity comparisons of several classic and contemporary RC models were made using a real data set. This included a more detailed review of a new RC model recently proposed in this journal, that used the within-subjects standard deviation (WSD) as the error term. It was suggested that the RC(WSD) was more sensitive to change and theoretically superior. The current paper demonstrated that even in the presence of mean practice effects, false-positive rates were comparable across models when reliability was good and initial and retest variances were equivalent. However, when variances differed, discrepancies in classification across models became evident. Notably, the RC using the WSD provided unacceptably high false-positive rates in this setting. It was considered that the WSD was never intended for measuring change in this manner. The WSD actually combines systematic and error variance. The systematic variance comes from measurable between-treatment differences, commonly referred to as practice effect. It was further demonstrated that removal of the systematic variance and appropriate modification of the residual error term for the purpose of testing individual change yielded an error term already published and criticized in the literature. A consensus on the RC approach is needed. To that end, further comparison of models under varied conditions is encouraged.
A proposed method to investigate reliability throughout a questionnaire.
Wentzel-Larsen, Tore; Norekvål, Tone M; Ulvik, Bjørg; Nygård, Ottar; Pripp, Are H
2011-10-05
Questionnaires are used extensively in medical and health care research and depend on validity and reliability. However, participants may differ in interest and awareness throughout long questionnaires, which can affect reliability of their answers. A method is proposed for "screening" of systematic change in random error, which could assess changed reliability of answers. A simulation study was conducted to explore whether systematic change in reliability, expressed as changed random error, could be assessed using unsupervised classification of subjects by cluster analysis (CA) and estimation of intraclass correlation coefficient (ICC). The method was also applied on a clinical dataset from 753 cardiac patients using the Jalowiec Coping Scale. The simulation study showed a relationship between the systematic change in random error throughout a questionnaire and the slope between the estimated ICC for subjects classified by CA and successive items in a questionnaire. This slope was proposed as an awareness measure--to assessing if respondents provide only a random answer or one based on a substantial cognitive effort. Scales from different factor structures of Jalowiec Coping Scale had different effect on this awareness measure. Even though assumptions in the simulation study might be limited compared to real datasets, the approach is promising for assessing systematic change in reliability throughout long questionnaires. Results from a clinical dataset indicated that the awareness measure differed between scales.
Moisture Forecast Bias Correction in GEOS DAS
NASA Technical Reports Server (NTRS)
Dee, D.
1999-01-01
Data assimilation methods rely on numerous assumptions about the errors involved in measuring and forecasting atmospheric fields. One of the more disturbing of these is that short-term model forecasts are assumed to be unbiased. In case of atmospheric moisture, for example, observational evidence shows that the systematic component of errors in forecasts and analyses is often of the same order of magnitude as the random component. we have implemented a sequential algorithm for estimating forecast moisture bias from rawinsonde data in the Goddard Earth Observing System Data Assimilation System (GEOS DAS). The algorithm is designed to remove the systematic component of analysis errors and can be easily incorporated in an existing statistical data assimilation system. We will present results of initial experiments that show a significant reduction of bias in the GEOS DAS moisture analyses.
NASA Technical Reports Server (NTRS)
Young, A. T.
1974-01-01
An overlooked systematic error exists in the apparent radial velocities of solar lines reflected from regions of Venus near the terminator, owing to a combination of the finite angular size of the Sun and its large (2 km/sec) equatorial velocity of rotation. This error produces an apparent, but fictitious, retrograde component of planetary rotation, typically on the order of 40 meters/sec. Spectroscopic, photometric, and radiometric evidence against a 4-day atmospheric rotation is also reviewed. The bulk of the somewhat contradictory evidence seems to favor slow motions, on the order of 5 m/sec, in the atmosphere of Venus; the 4-day rotation may be due to a traveling wave-like disturbance, not bulk motions, driven by the UV albedo differences.
Brest sea level record: a time series construction back to the early eighteenth century
NASA Astrophysics Data System (ADS)
Wöppelmann, Guy; Pouvreau, Nicolas; Simon, Bernard
2006-12-01
The completeness and the accuracy of the Brest sea level time series dating from 1807 make it suitable for long-term sea level trend studies. New data sets were recently discovered in the form of handwritten tabulations, including several decades of the eighteenth century. Sea level observations have been made in Brest since 1679. This paper presents the historical data sets which have been assembled so far. These data sets span approximately 300 years and together constitute the longest, near-continuous set of sea level information in France. However, an important question arises: Can we relate the past and the present-day records? We partially provide an answer to this question by analysing the documents of several historical libraries with the tidal data using a ‘data archaeology’ approach advocated by Woodworth ( Geophys Res Lett 26:1589 1592, 1999b). A second question arises concerning the accuracy of such records. Careful editing was undertaken by examining the residuals between tidal predictions and observations. It proved useful to remove the worst effects of timing errors, in particular the sundial correction to be applied prior to August 1, 1714. A refined correction based on sundial literature [Savoie, La gnomique, Editions Les Belles Lettres, Paris, 2001] is proposed, which eliminates the systematic offsets seen in the discrepancies in timing of the sea level measurements. The tidal analysis has also shown that shallow-water tidal harmonics at Brest causes a systematic difference of 0.023 m between mean sea level (MSL) and mean tide level (MTL). Thus, MTL should not be mixed with the time series of MSL because of this systematic offset. The study of the trends in MTL and MSL however indicates that MTL can be used as a proxy for MSL. Three linear trend periods are distinguished in the Brest MTL time series over the period 1807 2004. Our results support the recent findings of Holgate and Woodworth ( Geophys Res Lett) of an enhanced coastal sea level rise during the last decade compared to the global estimations of about 1.8 mm/year over longer periods (Douglas, J Geophys Res 96:6981 6992, 1991). The onset of the relatively large global sea level trends observed in the twentieth century is an important question in the science of climate change. Our findings point out to an ‘inflexion point’ at around 1890, which is remarkably close to that in 1880 found in the Liverpool record by Woodworth ( Geophys Res Lett 26:1589 1592, 1999b).
Aged-related Neural Changes during Memory Conjunction Errors
Giovanello, Kelly S.; Kensinger, Elizabeth A.; Wong, Alana T.; Schacter, Daniel L.
2013-01-01
Human behavioral studies demonstrate that healthy aging is often accompanied by increases in memory distortions or errors. Here we used event-related functional MRI to examine the neural basis of age-related memory distortions. We utilized the memory conjunction error paradigm, a laboratory procedure known to elicit high levels of memory errors. For older adults, right parahippocampal gyrus showed significantly greater activity during false than during accurate retrieval. We observed no regions in which activity was greater during false than during accurate retrieval for young adults. Young adults, however, showed significantly greater activity than old adults during accurate retrieval in right hippocampus. By contrast, older adults demonstrated greater activity than young adults during accurate retrieval in right inferior and middle prefrontal cortex. These data are consistent with the notion that age-related memory conjunction errors arise from dysfunction of hippocampal system mechanisms, rather than impairments in frontally-mediated monitoring processes. PMID:19445606
Text familiarity, word frequency, and sentential constraints in error detection.
Pilotti, Maura; Chodorow, Martin; Schauss, Frances
2009-12-01
The present study examines whether the frequency of an error-bearing word and its predictability, arising from sentential constraints and text familiarity, either independently or jointly, would impair error detection by making proofreading driven by top-down processes. Prior to a proofreading task, participants were asked to read, copy, memorize, or paraphrase sentences, half of which contained errors. These tasks represented a continuum of progressively more demanding and time-consuming activities, which were thought to lead to comparable increases in text familiarity and thus predictability. Proofreading times were unaffected by whether the sentences had been encountered earlier. Proofreading was slower and less accurate for high-frequency words and for highly constrained sentences. Prior memorization produced divergent effects on accuracy depending on sentential constraints. The latter finding suggested that a substantial level of predictability, such as that produced by memorizing highly constrained sentences, can increase the probability of overlooking errors.
High-precision pointing with the Sardinia Radio Telescope
NASA Astrophysics Data System (ADS)
Poppi, Sergio; Pernechele, Claudio; Pisanu, Tonino; Morsiani, Marco
2010-07-01
We present here the systems aimed to measure and minimize the pointing errors for the Sardinia Radio Telescope: they consist of an optical telescope to measure errors due to the mechanical structure deformations and a lasers system for the errors due to the subreflector displacement. We show here the results of the tests that we have done on the Medicina 32 meters VLBI radio telescope. The measurements demonstrate we can measure the pointing errors of the mechanical structure, with an accuracy of about ~1 arcsec. Moreover, we show the technique to measure the displacement of the subreflector, placed in the SRT at 22 meters from the main mirror, within +/-0.1 mm from its optimal position. These measurements show that we can obtain the needed accuracy to correct also the non repeatable pointing errors, which arise on time scale varying from seconds to minutes.
Total error shift patterns for daily CT on rails image-guided radiotherapy to the prostate bed
2011-01-01
Background To evaluate the daily total error shift patterns on post-prostatectomy patients undergoing image guided radiotherapy (IGRT) with a diagnostic quality computer tomography (CT) on rails system. Methods A total of 17 consecutive post-prostatectomy patients receiving adjuvant or salvage IMRT using CT-on-rails IGRT were analyzed. The prostate bed's daily total error shifts were evaluated for a total of 661 CT scans. Results In the right-left, cranial-caudal, and posterior-anterior directions, 11.5%, 9.2%, and 6.5% of the 661 scans required no position adjustments; 75.3%, 66.1%, and 56.8% required a shift of 1 - 5 mm; 11.5%, 20.9%, and 31.2% required a shift of 6 - 10 mm; and 1.7%, 3.8%, and 5.5% required a shift of more than 10 mm, respectively. There was evidence of correlation between the x and y, x and z, and y and z axes in 3, 3, and 3 of 17 patients, respectively. Univariate (ANOVA) analysis showed that the total error pattern was random in the x, y, and z axis for 10, 5, and 2 of 17 patients, respectively, and systematic for the rest. Multivariate (MANOVA) analysis showed that the (x,y), (x,z), (y,z), and (x, y, z) total error pattern was random in 5, 1, 1, and 1 of 17 patients, respectively, and systematic for the rest. Conclusions The overall daily total error shift pattern for these 17 patients simulated with an empty bladder, and treated with CT on rails IGRT was predominantly systematic. Despite this, the temporal vector trends showed complex behaviors and unpredictable changes in magnitude and direction. These findings highlight the importance of using daily IGRT in post-prostatectomy patients. PMID:22024279
Powell, Laurie Ehlhardt; Glang, Ann; Ettel, Deborah; Todis, Bonnie; Sohlberg, McKay; Albin, Richard
2012-01-01
The goal of this study was to experimentally evaluate systematic instruction compared with trial-and-error learning (conventional instruction) applied to assistive technology for cognition (ATC), in a double blind, pretest-posttest, randomized controlled trial. Twenty-nine persons with moderate-severe cognitive impairments due to acquired brain injury (15 in systematic instruction group; 14 in conventional instruction) completed the study. Both groups received 12, 45-minute individual training sessions targeting selected skills on the Palm Tungsten E2 personal digital assistant (PDA). A criterion-based assessment of PDA skills was used to evaluate accuracy, fluency/efficiency, maintenance, and generalization of skills. There were no significant differences between groups at immediate posttest with regard to accuracy and fluency. However, significant differences emerged at 30-day follow-up in favor of systematic instruction. Furthermore, systematic instruction participants performed significantly better at immediate posttest generalizing trained PDA skills when interacting with people other than the instructor. These results demonstrate that systematic instruction applied to ATC results in better skill maintenance and generalization than trial-and-error learning for individuals with moderate-severe cognitive impairments due to acquired brain injury. Implications, study limitations, and directions for future research are discussed. PMID:22264146
Analyzing false positives of four questions in the Force Concept Inventory
NASA Astrophysics Data System (ADS)
Yasuda, Jun-ichiro; Mae, Naohiro; Hull, Michael M.; Taniguchi, Masa-aki
2018-06-01
In this study, we analyze the systematic error from false positives of the Force Concept Inventory (FCI). We compare the systematic errors of question 6 (Q.6), Q.7, and Q.16, for which clearly erroneous reasoning has been found, with Q.5, for which clearly erroneous reasoning has not been found. We determine whether or not a correct response to a given FCI question is a false positive using subquestions. In addition to the 30 original questions, subquestions were introduced for Q.5, Q.6, Q.7, and Q.16. This modified version of the FCI was administered to 1145 university students in Japan from 2015 to 2017. In this paper, we discuss our finding that the systematic errors of Q.6, Q.7, and Q.16 are much larger than that of Q.5 for students with mid-level FCI scores. Furthermore, we find that, averaged over the data sample, the sum of the false positives from Q.5, Q.6, Q.7, and Q.16 is about 10% of the FCI score of a midlevel student.
NASA Astrophysics Data System (ADS)
Henry, William; Jefferson Lab Hall A Collaboration
2017-09-01
Jefferson Lab's cutting-edge parity-violating electron scattering program has increasingly stringent requirements for systematic errors. Beam polarimetry is often one of the dominant systematic errors in these experiments. A new Møller Polarimeter in Hall A of Jefferson Lab (JLab) was installed in 2015 and has taken first measurements for a polarized scattering experiment. Upcoming parity violation experiments in Hall A include CREX, PREX-II, MOLLER and SOLID with the latter two requiring <0.5% precision on beam polarization measurements. The polarimeter measures the Møller scattering rates of the polarized electron beam incident upon an iron target placed in a saturating magnetic field. The spectrometer consists of four focusing quadrapoles and one momentum selection dipole. The detector is designed to measure the scattered and knock out target electrons in coincidence. Beam polarization is extracted by constructing an asymmetry from the scattering rates when the incident electron spin is parallel and anti-parallel to the target electron spin. Initial data will be presented. Sources of systematic errors include target magnetization, spectrometer acceptance, the Levchuk effect, and radiative corrections which will be discussed. National Science Foundation.
NASA Technical Reports Server (NTRS)
James, W. P. (Principal Investigator); Hill, J. M.; Bright, J. B.
1977-01-01
The author has identified the following significant results. Correlations between the satellite radiance values water color, Secchi disk visibility, turbidity, and attenuation coefficients were generally good. The residual was due to several factors including systematic errors in the remotely sensed data, errors, small time and space variations in the water quality measurements, and errors caused by experimental design. Satellite radiance values were closely correlated with the optical properties of the water.
Drought Persistence in Models and Observations
NASA Astrophysics Data System (ADS)
Moon, Heewon; Gudmundsson, Lukas; Seneviratne, Sonia
2017-04-01
Many regions of the world have experienced drought events that persisted several years and caused substantial economic and ecological impacts in the 20th century. However, it remains unclear whether there are significant trends in the frequency or severity of these prolonged drought events. In particular, an important issue is linked to systematic biases in the representation of persistent drought events in climate models, which impedes analysis related to the detection and attribution of drought trends. This study assesses drought persistence errors in global climate model (GCM) simulations from the 5th phase of Coupled Model Intercomparison Project (CMIP5), in the period of 1901-2010. The model simulations are compared with five gridded observational data products. The analysis focuses on two aspects: the identification of systematic biases in the models and the partitioning of the spread of drought-persistence-error into four possible sources of uncertainty: model uncertainty, observation uncertainty, internal climate variability and the estimation error of drought persistence. We use monthly and yearly dry-to-dry transition probabilities as estimates for drought persistence with drought conditions defined as negative precipitation anomalies. For both time scales we find that most model simulations consistently underestimated drought persistence except in a few regions such as India and Eastern South America. Partitioning the spread of the drought-persistence-error shows that at the monthly time scale model uncertainty and observation uncertainty are dominant, while the contribution from internal variability does play a minor role in most cases. At the yearly scale, the spread of the drought-persistence-error is dominated by the estimation error, indicating that the partitioning is not statistically significant, due to a limited number of considered time steps. These findings reveal systematic errors in the representation of drought persistence in current climate models and highlight the main contributors of uncertainty of drought-persistence-error. Future analyses will focus on investigating the temporal propagation of drought persistence to better understand the causes for the identified errors in the representation of drought persistence in state-of-the-art climate models.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gonzalez, P; Olaciregui-Ruiz, I; Mijnheer, B
2016-06-15
Purpose: To investigate the sensitivity of an EPID-based 3D dose verification system to detect delivery errors in VMAT treatments. Methods: For this study 41 EPID-reconstructed 3D in vivo dose distributions of 15 different VMAT plans (H&N, lung, prostate and rectum) were selected. To simulate the effect of delivery errors, their TPS plans were modified by: 1) scaling of the monitor units by ±3% and ±6% and 2) systematic shifting of leaf bank positions by ±1mm, ±2mm and ±5mm. The 3D in vivo dose distributions where then compared to the unmodified and modified treatment plans. To determine the detectability of themore » various delivery errors, we made use of a receiver operator characteristic (ROC) methodology. True positive and false positive rates were calculated as a function of the γ-parameters γmean, γ1% (near-maximum γ) and the PTV dose parameter ΔD{sub 50} (i.e. D{sub 50}(EPID)-D{sub 50}(TPS)). The ROC curve is constructed by plotting the true positive rate vs. the false positive rate. The area under the ROC curve (AUC) then serves as a measure of the performance of the EPID dosimetry system in detecting a particular error; an ideal system has AUC=1. Results: The AUC ranges for the machine output errors and systematic leaf position errors were [0.64 – 0.93] and [0.48 – 0.92] respectively using γmean, [0.57 – 0.79] and [0.46 – 0.85] using γ1% and [0.61 – 0.77] and [ 0.48 – 0.62] using ΔD{sub 50}. Conclusion: For the verification of VMAT deliveries, the parameter γmean is the best discriminator for the detection of systematic leaf position errors and monitor unit scaling errors. Compared to γmean and γ1%, the parameter ΔD{sub 50} performs worse as a discriminator in all cases.« less
Strategic planning to reduce medical errors: Part I--diagnosis.
Waldman, J Deane; Smith, Howard L
2012-01-01
Despite extensive dialogue and a continuing stream of proposed medical practice revisions, medical errors and adverse impacts persist. Connectivity of vital elements is often underestimated or not fully understood. This paper analyzes medical errors from a systems dynamics viewpoint (Part I). Our analysis suggests in Part II that the most fruitful strategies for dissolving medical errors include facilitating physician learning, educating patients about appropriate expectations surrounding treatment regimens, and creating "systematic" patient protections rather than depending on (nonexistent) perfect providers.
Quality Assurance of Chemical Measurements.
ERIC Educational Resources Information Center
Taylor, John K.
1981-01-01
Reviews aspects of quality control (methods to control errors) and quality assessment (verification that systems are operating within acceptable limits) including an analytical measurement system, quality control by inspection, control charts, systematic errors, and use of SRMs, materials for which properties are certified by the National Bureau…
Rational-Emotive Therapy versus Systematic Desensitization: A Comment on Moleski and Tosi.
ERIC Educational Resources Information Center
Atkinson, Leslie
1983-01-01
Questioned the statistical analyses of the Moleski and Tosi investigation of rational-emotive therapy versus systematic desensitization. Suggested means for lowering the error rate through a more efficient experimental design. Recommended a reanalysis of the original data. (LLL)
ASME B89.4.19 Performance Evaluation Tests and Geometric Misalignments in Laser Trackers
Muralikrishnan, B.; Sawyer, D.; Blackburn, C.; Phillips, S.; Borchardt, B.; Estler, W. T.
2009-01-01
Small and unintended offsets, tilts, and eccentricity of the mechanical and optical components in laser trackers introduce systematic errors in the measured spherical coordinates (angles and range readings) and possibly in the calculated lengths of reference artifacts. It is desirable that the tests described in the ASME B89.4.19 Standard [1] be sensitive to these geometric misalignments so that any resulting systematic errors are identified during performance evaluation. In this paper, we present some analysis, using error models and numerical simulation, of the sensitivity of the length measurement system tests and two-face system tests in the B89.4.19 Standard to misalignments in laser trackers. We highlight key attributes of the testing strategy adopted in the Standard and propose new length measurement system tests that demonstrate improved sensitivity to some misalignments. Experimental results with a tracker that is not properly error corrected for the effects of the misalignments validate claims regarding the proposed new length tests. PMID:27504211
Hoy, Robert S; Foteinopoulou, Katerina; Kröger, Martin
2009-09-01
Primitive path analyses of entanglements are performed over a wide range of chain lengths for both bead spring and atomistic polyethylene polymer melts. Estimators for the entanglement length N_{e} which operate on results for a single chain length N are shown to produce systematic O(1/N) errors. The mathematical roots of these errors are identified as (a) treating chain ends as entanglements and (b) neglecting non-Gaussian corrections to chain and primitive path dimensions. The prefactors for the O(1/N) errors may be large; in general their magnitude depends both on the polymer model and the method used to obtain primitive paths. We propose, derive, and test new estimators which eliminate these systematic errors using information obtainable from the variation in entanglement characteristics with chain length. The new estimators produce accurate results for N_{e} from marginally entangled systems. Formulas based on direct enumeration of entanglements appear to converge faster and are simpler to apply.
An, Zhao; Wen-Xin, Zhang; Zhong, Yao; Yu-Kuan, Ma; Qing, Liu; Hou-Lang, Duan; Yi-di, Shang
2016-06-29
To optimize and simplify the survey method of Oncomelania hupensis snail in marshland endemic region of schistosomiasis and increase the precision, efficiency and economy of the snail survey. A quadrate experimental field was selected as the subject of 50 m×50 m size in Chayegang marshland near Henghu farm in the Poyang Lake region and a whole-covered method was adopted to survey the snails. The simple random sampling, systematic sampling and stratified random sampling methods were applied to calculate the minimum sample size, relative sampling error and absolute sampling error. The minimum sample sizes of the simple random sampling, systematic sampling and stratified random sampling methods were 300, 300 and 225, respectively. The relative sampling errors of three methods were all less than 15%. The absolute sampling errors were 0.221 7, 0.302 4 and 0.047 8, respectively. The spatial stratified sampling with altitude as the stratum variable is an efficient approach of lower cost and higher precision for the snail survey.
Bolann, B J; Asberg, A
2004-01-01
The deviation of test results from patients' homeostatic set points in steady-state conditions may complicate interpretation of the results and the comparison of results with clinical decision limits. In this study the total deviation from the homeostatic set point is defined as the maximum absolute deviation for 95% of measurements, and we present analytical quality requirements that prevent analytical error from increasing this deviation to more than about 12% above the value caused by biology alone. These quality requirements are: 1) The stable systematic error should be approximately 0, and 2) a systematic error that will be detected by the control program with 90% probability, should not be larger than half the value of the combined analytical and intra-individual standard deviation. As a result, when the most common control rules are used, the analytical standard deviation may be up to 0.15 times the intra-individual standard deviation. Analytical improvements beyond these requirements have little impact on the interpretability of measurement results.
NASA Astrophysics Data System (ADS)
Kirstetter, P.; Hong, Y.; Gourley, J. J.; Chen, S.; Flamig, Z.; Zhang, J.; Howard, K.; Petersen, W. A.
2011-12-01
Proper characterization of the error structure of TRMM Precipitation Radar (PR) quantitative precipitation estimation (QPE) is needed for their use in TRMM combined products, water budget studies and hydrological modeling applications. Due to the variety of sources of error in spaceborne radar QPE (attenuation of the radar signal, influence of land surface, impact of off-nadir viewing angle, etc.) and the impact of correction algorithms, the problem is addressed by comparison of PR QPEs with reference values derived from ground-based measurements (GV) using NOAA/NSSL's National Mosaic QPE (NMQ) system. An investigation of this subject has been carried out at the PR estimation scale (instantaneous and 5 km) on the basis of a 3-month-long data sample. A significant effort has been carried out to derive a bias-corrected, robust reference rainfall source from NMQ. The GV processing details will be presented along with preliminary results of PR's error characteristics using contingency table statistics, probability distribution comparisons, scatter plots, semi-variograms, and systematic biases and random errors.
Reliable Channel-Adapted Error Correction: Bacon-Shor Code Recovery from Amplitude Damping
NASA Astrophysics Data System (ADS)
Piedrafita, Álvaro; Renes, Joseph M.
2017-12-01
We construct two simple error correction schemes adapted to amplitude damping noise for Bacon-Shor codes and investigate their prospects for fault-tolerant implementation. Both consist solely of Clifford gates and require far fewer qubits, relative to the standard method, to achieve exact correction to a desired order in the damping rate. The first, employing one-bit teleportation and single-qubit measurements, needs only one-fourth as many physical qubits, while the second, using just stabilizer measurements and Pauli corrections, needs only half. The improvements stem from the fact that damping events need only be detected, not corrected, and that effective phase errors arising due to undamped qubits occur at a lower rate than damping errors. For error correction that is itself subject to damping noise, we show that existing fault-tolerance methods can be employed for the latter scheme, while the former can be made to avoid potential catastrophic errors and can easily cope with damping faults in ancilla qubits.
Hessian matrix approach for determining error field sensitivity to coil deviations.
Zhu, Caoxiang; Hudson, Stuart R.; Lazerson, Samuel A.; ...
2018-03-15
The presence of error fields has been shown to degrade plasma confinement and drive instabilities. Error fields can arise from many sources, but are predominantly attributed to deviations in the coil geometry. In this paper, we introduce a Hessian matrix approach for determining error field sensitivity to coil deviations. A primary cost function used for designing stellarator coils, the surface integral of normalized normal field errors, was adopted to evaluate the deviation of the generated magnetic field from the desired magnetic field. The FOCUS code [Zhu et al., Nucl. Fusion 58(1):016008 (2018)] is utilized to provide fast and accurate calculationsmore » of the Hessian. The sensitivities of error fields to coil displacements are then determined by the eigenvalues of the Hessian matrix. A proof-of-principle example is given on a CNT-like configuration. We anticipate that this new method could provide information to avoid dominant coil misalignments and simplify coil designs for stellarators.« less
Seli, Paul; Cheyne, James Allan; Smilek, Daniel
2012-03-01
In two studies of a GO-NOGO task assessing sustained attention, we examined the effects of (1) altering speed-accuracy trade-offs through instructions (emphasizing both speed and accuracy or accuracy only) and (2) auditory alerts distributed throughout the task. Instructions emphasizing accuracy reduced errors and changed the distribution of GO trial RTs. Additionally, correlations between errors and increasing RTs produced a U-function; excessively fast and slow RTs accounted for much of the variance of errors. Contrary to previous reports, alerts increased errors and RT variability. The results suggest that (1) standard instructions for sustained attention tasks, emphasizing speed and accuracy equally, produce errors arising from attempts to conform to the misleading requirement for speed, which become conflated with attention-lapse produced errors and (2) auditory alerts have complex, and sometimes deleterious, effects on attention. We argue that instructions emphasizing accuracy provide a more precise assessment of attention lapses in sustained attention tasks. Copyright © 2011 Elsevier Inc. All rights reserved.
Hessian matrix approach for determining error field sensitivity to coil deviations.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhu, Caoxiang; Hudson, Stuart R.; Lazerson, Samuel A.
The presence of error fields has been shown to degrade plasma confinement and drive instabilities. Error fields can arise from many sources, but are predominantly attributed to deviations in the coil geometry. In this paper, we introduce a Hessian matrix approach for determining error field sensitivity to coil deviations. A primary cost function used for designing stellarator coils, the surface integral of normalized normal field errors, was adopted to evaluate the deviation of the generated magnetic field from the desired magnetic field. The FOCUS code [Zhu et al., Nucl. Fusion 58(1):016008 (2018)] is utilized to provide fast and accurate calculationsmore » of the Hessian. The sensitivities of error fields to coil displacements are then determined by the eigenvalues of the Hessian matrix. A proof-of-principle example is given on a CNT-like configuration. We anticipate that this new method could provide information to avoid dominant coil misalignments and simplify coil designs for stellarators.« less
NASA Astrophysics Data System (ADS)
Lew, E. J.; Butenhoff, C. L.; Karmakar, S.; Rice, A. L.; Khalil, A. K.
2017-12-01
Methane is the second most important greenhouse gas after carbon dioxide. In efforts to control emissions, a careful examination of the methane budget and source strengths is required. To determine methane surface fluxes, Bayesian methods are often used to provide top-down constraints. Inverse modeling derives unknown fluxes using observed methane concentrations, a chemical transport model (CTM) and prior information. The Bayesian inversion reduces prior flux uncertainties by exploiting information content in the data. While the Bayesian formalism produces internal error estimates of source fluxes, systematic or external errors that arise from user choices in the inversion scheme are often much larger. Here we examine model sensitivity and uncertainty of our inversion under different observation data sets and CTM grid resolution. We compare posterior surface fluxes using the data product GLOBALVIEW-CH4 against the event-level molar mixing ratio data available from NOAA. GLOBALVIEW-CH4 is a collection of CH4 concentration estimates from 221 sites, collected by 12 laboratories, that have been interpolated and extracted to provide weekly records from 1984-2008. Differently, the event-level NOAA data records methane mixing ratios field measurements from 102 sites, containing sampling frequency irregularities and gaps in time. Furthermore, the sampling platform types used by the data sets may influence the posterior flux estimates, namely fixed surface, tower, ship and aircraft sites. To explore the sensitivity of the posterior surface fluxes to the observation network geometry, inversions composed of all sites, only aircraft, only ship, only tower and only fixed surface sites, are performed and compared. Also, we investigate the sensitivity of the error reduction associated with the resolution of the GEOS-Chem simulation (4°×5° vs 2°×2.5°) used to calculate the response matrix. Using a higher resolution grid decreased the model-data error at most sites, thereby increasing the information at that site. These different inversions—event-level and interpolated data, higher and lower resolutions—are compared using an ensemble of descriptive and comparative statistics. Analyzing the sensitivity of the inverse model leads to more accurate estimates of the methane source category uncertainty.
Evaluation of ship-based sediment flux measurements by ADCPs in tidal flows
NASA Astrophysics Data System (ADS)
Becker, Marius; Maushake, Christian; Grünler, Steffen; Winter, Christian
2017-04-01
In the past decades acoustic backscatter calibration developed into a frequently applied technique to measure fluxes of suspended sediments in rivers and estuaries. Data is mainly acquired using single-frequency profiling devices, such as ADCPs. In this case, variations of acoustic particle properties may have a significant impact on the calibration with respect to suspended sediment concentration, but associated effects are rarely considered. Further challenges regarding flux determination arise from incomplete vertical and lateral coverage of the cross-section, and the small ratio of the residual transport to the tidal transport, depending on the tidal prism. We analyzed four sets of 13h cross-sectional ADCP data, collected at different locations in the range of the turbidity zone of the Weser estuary, North Sea, Germany. Vertical LISST, OBS and CTD measurements were taken very hour. During the calibration sediment absorption was taken into account. First, acoustic properties were estimated using LISST particle size distributions. Due to the tidal excursion and displacement of the turbidity zone, acoustic properties of particles changed during the tidal cycle, at all locations. Applying empirical functions, the lowest backscattering cross-section and highest sediment absorption coefficient were found in the center of the turbidity zone. Outside the tidally averaged location of the turbidity zone, changes of acoustic parameters were caused mainly by advection. In the turbidity zone, these properties were also affected by settling and entrainment, inducing vertical differences and systematic errors in concentration. In general, due to the iterative correction of sediment absorption along the acoustic path, local errors in concentration propagate and amplify exponentially. Based on reference concentration obtained from water samples and OBS data, we quantified these errors and their effect on cross-sectional averaged concentration and sediment flux. We found that errors are effectively decreased by applying calibration parameters interpolated in time, and by an optimization of the sediment absorption coefficient. We further discuss practical aspects of residual flux determination in tidal environments and of measuring strategies in relation to site-specific tidal dynamics.
In-situ Calibration Methods for Phased Array High Frequency Radars
NASA Astrophysics Data System (ADS)
Flament, P. J.; Flament, M.; Chavanne, C.; Flores-vidal, X.; Rodriguez, I.; Marié, L.; Hilmer, T.
2016-12-01
HF radars measure currents through the Doppler-shift of electromagnetic waves Bragg-scattered by surface gravity waves. While modern clocks and digital synthesizers yield range errors negligible compared to the bandwidth-limited range resolution, azimuth calibration issues arise for beam-forming phased arrays. Sources of errors in the phases of the received waves can be internal to the radar system (phase errors of filters, cable lengths, antenna tuning) and geophysical (standing waves, propagation and refraction anomalies). They result in azimuthal biases (which can be range-dependent) and beam-forming side-lobes (which induce Doppler ambiguities). We analyze the experimental calibrations of 17 deployments of WERA HF radars, performed between 2003 and 2012 in Hawaii, the Adriatic, France, Mexico and the Philippines. Several strategies were attempted: (i) passive reception of continuous multi-frequency transmitters on GPS-tracked boats, cars, and drones; (ii) bi-static calibrations of radars in mutual view; (iii) active echoes from vessels of opportunity of unknown positions or tracked through AIS; (iv) interference of unknown remote transmitters with the chirped local oscillator. We found that: (a) for antennas deployed on the sea shore, a single-azimuth calibration is sufficient to correct phases within a typical beam-forming azimuth range; (b) after applying this azimuth-independent correction, residual pointing errors are 1-2 deg. rms; (c) for antennas deployed on irregular cliffs or hills, back from shore, systematic biases appear for some azimuths at large incidence angles, suggesting that some of the ground-wave electromagnetic energy propagates in a terrain-following mode between the sea shore and the antennas; (d) for some sites, fluctuations of 10-25 deg. in radio phase at 20-40 deg. azimuthal period, not significantly correlated among antennas, are omnipresent in calibrations along a constant-range circle, suggesting standing waves or multiple paths in the presence of reflecting structures (buildings, fences), or possibly fractal nature of the wavefronts; (e) amplitudes lack stability in time and azimuth to be usable as a-priori calibrations, confirming the accepted method of re-normalizing amplitudes by the signal of nearby cells prior to beam-forming.
The sensitivity of patient specific IMRT QC to systematic MLC leaf bank offset errors.
Rangel, Alejandra; Palte, Gesa; Dunscombe, Peter
2010-07-01
Patient specific IMRT QC is performed routinely in many clinics as a safeguard against errors and inaccuracies which may be introduced during the complex planning, data transfer, and delivery phases of this type of treatment. The purpose of this work is to evaluate the feasibility of detecting systematic errors in MLC leaf bank position with patient specific checks. 9 head and neck (H&N) and 14 prostate IMRT beams were delivered using MLC files containing systematic offsets (+/- 1 mm in two banks, +/- 0.5 mm in two banks, and 1 mm in one bank of leaves). The beams were measured using both MAPCHECK (Sun Nuclear Corp., Melbourne, FL) and the aS1000 electronic portal imaging device (Varian Medical Systems, Palo Alto, CA). Comparisons with calculated fields, without offsets, were made using commonly adopted criteria including absolute dose (AD) difference, relative dose difference, distance to agreement (DTA), and the gamma index. The criteria most sensitive to systematic leaf bank offsets were the 3% AD, 3 mm DTA for MAPCHECK and the gamma index with 2% AD and 2 mm DTA for the EPID. The criterion based on the relative dose measurements was the least sensitive to MLC offsets. More highly modulated fields, i.e., H&N, showed greater changes in the percentage of passing points due to systematic MLC inaccuracy than prostate fields. None of the techniques or criteria tested is sufficiently sensitive, with the population of IMRT fields, to detect a systematic MLC offset at a clinically significant level on an individual field. Patient specific QC cannot, therefore, substitute for routine QC of the MLC itself.
Pion mass dependence of the HVP contribution to muon g - 2
NASA Astrophysics Data System (ADS)
Golterman, Maarten; Maltman, Kim; Peris, Santiago
2018-03-01
One of the systematic errors in some of the current lattice computations of the HVP contribution to the muon anomalous magnetic moment g - 2 is that associated with the extrapolation to the physical pion mass. We investigate this extrapolation assuming lattice pion masses in the range of 220 to 440 MeV with the help of two-loop chiral perturbation theory, and find that such an extrapolation is unlikely to lead to control of this systematic error at the 1% level. This remains true even if various proposed tricks to improve the chiral extrapolation are taken into account.
Comparison of different source calculations in two-nucleon channel at large quark mass
NASA Astrophysics Data System (ADS)
Yamazaki, Takeshi; Ishikawa, Ken-ichi; Kuramashi, Yoshinobu
2018-03-01
We investigate a systematic error coming from higher excited state contributions in the energy shift of light nucleus in the two-nucleon channel by comparing two different source calculations with the exponential and wall sources. Since it is hard to obtain a clear signal of the wall source correlation function in a plateau region, we employ a large quark mass as the pion mass is 0.8 GeV in quenched QCD. We discuss the systematic error in the spin-triplet channel of the two-nucleon system, and the volume dependence of the energy shift.
NASA Technical Reports Server (NTRS)
Flamant, Cyrille N.; Schwemmer, Geary K.; Korb, C. Laurence; Evans, Keith D.; Palm, Stephen P.
1999-01-01
Remote airborne measurements of the vertical and horizontal structure of the atmospheric pressure field in the lower troposphere are made with an oxygen differential absorption lidar (DIAL). A detailed analysis of this measurement technique is provided which includes corrections for imprecise knowledge of the detector background level, the oxygen absorption fine parameters, and variations in the laser output energy. In addition, we analyze other possible sources of systematic errors including spectral effects related to aerosol and molecular scattering interference by rotational Raman scattering and interference by isotopic oxygen fines.
Production and detection of atomic hexadecapole at Earth's magnetic field.
Acosta, V M; Auzinsh, M; Gawlik, W; Grisins, P; Higbie, J M; Jackson Kimball, D F; Krzemien, L; Ledbetter, M P; Pustelny, S; Rochester, S M; Yashchuk, V V; Budker, D
2008-07-21
Optical magnetometers measure magnetic fields with extremely high precision and without cryogenics. However, at geomagnetic fields, important for applications from landmine removal to archaeology, they suffer from nonlinear Zeeman splitting, leading to systematic dependence on sensor orientation. We present experimental results on a method of eliminating this systematic error, using the hexadecapole atomic polarization moment. In particular, we demonstrate selective production of the atomic hexadecapole moment at Earth's magnetic field and verify its immunity to nonlinear Zeeman splitting. This technique promises to eliminate directional errors in all-optical atomic magnetometers, potentially improving their measurement accuracy by several orders of magnitude.
O'Connor, Annette M; Totton, Sarah C; Cullen, Jonah N; Ramezani, Mahmood; Kalivarapu, Vijay; Yuan, Chaohui; Gilbert, Stephen B
2018-01-01
Systematic reviews are increasingly using data from preclinical animal experiments in evidence networks. Further, there are ever-increasing efforts to automate aspects of the systematic review process. When assessing systematic bias and unit-of-analysis errors in preclinical experiments, it is critical to understand the study design elements employed by investigators. Such information can also inform prioritization of automation efforts that allow the identification of the most common issues. The aim of this study was to identify the design elements used by investigators in preclinical research in order to inform unique aspects of assessment of bias and error in preclinical research. Using 100 preclinical experiments each related to brain trauma and toxicology, we assessed design elements described by the investigators. We evaluated Methods and Materials sections of reports for descriptions of the following design elements: 1) use of comparison group, 2) unit of allocation of the interventions to study units, 3) arrangement of factors, 4) method of factor allocation to study units, 5) concealment of the factors during allocation and outcome assessment, 6) independence of study units, and 7) nature of factors. Many investigators reported using design elements that suggested the potential for unit-of-analysis errors, i.e., descriptions of repeated measurements of the outcome (94/200) and descriptions of potential for pseudo-replication (99/200). Use of complex factor arrangements was common, with 112 experiments using some form of factorial design (complete, incomplete or split-plot-like). In the toxicology dataset, 20 of the 100 experiments appeared to use a split-plot-like design, although no investigators used this term. The common use of repeated measures and factorial designs means understanding bias and error in preclinical experimental design might require greater expertise than simple parallel designs. Similarly, use of complex factor arrangements creates novel challenges for accurate automation of data extraction and bias and error assessment in preclinical experiments.
Neural network approximation of nonlinearity in laser nano-metrology system based on TLMI
NASA Astrophysics Data System (ADS)
Olyaee, Saeed; Hamedi, Samaneh
2011-02-01
In this paper, an approach based on neural network (NN) for nonlinearity modeling in a nano-metrology system using three-longitudinal-mode laser heterodyne interferometer (TLMI) for length and displacement measurements is presented. We model nonlinearity errors that arise from elliptically and non-orthogonally polarized laser beams, rotational error in the alignment of laser head with respect to the polarizing beam splitter, rotational error in the alignment of the mixing polarizer, and unequal transmission coefficients in the polarizing beam splitter. Here we use a neural network algorithm based on the multi-layer perceptron (MLP) network. The simulation results show that multi-layer feed forward perceptron network is successfully applicable to real noisy interferometer signals.
Error in total ozone measurements arising from aerosol attenuation
NASA Technical Reports Server (NTRS)
Thomas, R. W. L.; Basher, R. E.
1979-01-01
A generalized least squares method for deducing both total ozone and aerosol extinction spectrum parameters from Dobson spectrophotometer measurements was developed. An error analysis applied to this system indicates that there is little advantage to additional measurements once a sufficient number of line pairs have been employed to solve for the selected detail in the attenuation model. It is shown that when there is a predominance of small particles (less than about 0.35 microns in diameter) the total ozone from the standard AD system is too high by about one percent. When larger particles are present the derived total ozone may be an overestimate or an underestimate but serious errors occur only for narrow polydispersions.
Phantom Effects in Multilevel Compositional Analysis: Problems and Solutions
ERIC Educational Resources Information Center
Pokropek, Artur
2015-01-01
This article combines statistical and applied research perspective showing problems that might arise when measurement error in multilevel compositional effects analysis is ignored. This article focuses on data where independent variables are constructed measures. Simulation studies are conducted evaluating methods that could overcome the…
Pilots of the future - Human or computer?
NASA Technical Reports Server (NTRS)
Chambers, A. B.; Nagel, D. C.
1985-01-01
In connection with the occurrence of aircraft accidents and the evolution of the air-travel system, questions arise regarding the computer's potential for making fundamental contributions to improving the safety and reliability of air travel. An important result of an analysis of the causes of aircraft accidents is the conclusion that humans - 'pilots and other personnel' - are implicated in well over half of the accidents which occur. Over 70 percent of the incident reports contain evidence of human error. In addition, almost 75 percent show evidence of an 'information-transfer' problem. Thus, the question arises whether improvements in air safety could be achieved by removing humans from control situations. In an attempt to answer this question, it is important to take into account also certain advantages which humans have in comparison to computers. Attention is given to human error and the effects of technology, the motivation to automate, aircraft automation at the crossroads, the evolution of cockpit automation, and pilot factors.
Phylogenomics of Lophotrochozoa with Consideration of Systematic Error.
Kocot, Kevin M; Struck, Torsten H; Merkel, Julia; Waits, Damien S; Todt, Christiane; Brannock, Pamela M; Weese, David A; Cannon, Johanna T; Moroz, Leonid L; Lieb, Bernhard; Halanych, Kenneth M
2017-03-01
Phylogenomic studies have improved understanding of deep metazoan phylogeny and show promise for resolving incongruences among analyses based on limited numbers of loci. One region of the animal tree that has been especially difficult to resolve, even with phylogenomic approaches, is relationships within Lophotrochozoa (the animal clade that includes molluscs, annelids, and flatworms among others). Lack of resolution in phylogenomic analyses could be due to insufficient phylogenetic signal, limitations in taxon and/or gene sampling, or systematic error. Here, we investigated why lophotrochozoan phylogeny has been such a difficult question to answer by identifying and reducing sources of systematic error. We supplemented existing data with 32 new transcriptomes spanning the diversity of Lophotrochozoa and constructed a new set of Lophotrochozoa-specific core orthologs. Of these, 638 orthologous groups (OGs) passed strict screening for paralogy using a tree-based approach. In order to reduce possible sources of systematic error, we calculated branch-length heterogeneity, evolutionary rate, percent missing data, compositional bias, and saturation for each OG and analyzed increasingly stricter subsets of only the most stringent (best) OGs for these five variables. Principal component analysis of the values for each factor examined for each OG revealed that compositional heterogeneity and average patristic distance contributed most to the variance observed along the first principal component while branch-length heterogeneity and, to a lesser extent, saturation contributed most to the variance observed along the second. Missing data did not strongly contribute to either. Additional sensitivity analyses examined effects of removing taxa with heterogeneous branch lengths, large amounts of missing data, and compositional heterogeneity. Although our analyses do not unambiguously resolve lophotrochozoan phylogeny, we advance the field by reducing the list of viable hypotheses. Moreover, our systematic approach for dissection of phylogenomic data can be applied to explore sources of incongruence and poor support in any phylogenomic data set. [Annelida; Brachiopoda; Bryozoa; Entoprocta; Mollusca; Nemertea; Phoronida; Platyzoa; Polyzoa; Spiralia; Trochozoa.]. © The Author(s) 2016. Published by Oxford University Press, on behalf of the Society of Systematic Biologists. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
NASA Astrophysics Data System (ADS)
Määttä, A.; Laine, M.; Tamminen, J.; Veefkind, J. P.
2014-05-01
Satellite instruments are nowadays successfully utilised for measuring atmospheric aerosol in many applications as well as in research. Therefore, there is a growing need for rigorous error characterisation of the measurements. Here, we introduce a methodology for quantifying the uncertainty in the retrieval of aerosol optical thickness (AOT). In particular, we concentrate on two aspects: uncertainty due to aerosol microphysical model selection and uncertainty due to imperfect forward modelling. We apply the introduced methodology for aerosol optical thickness retrieval of the Ozone Monitoring Instrument (OMI) on board NASA's Earth Observing System (EOS) Aura satellite, launched in 2004. We apply statistical methodologies that improve the uncertainty estimates of the aerosol optical thickness retrieval by propagating aerosol microphysical model selection and forward model error more realistically. For the microphysical model selection problem, we utilise Bayesian model selection and model averaging methods. Gaussian processes are utilised to characterise the smooth systematic discrepancies between the measured and modelled reflectances (i.e. residuals). The spectral correlation is composed empirically by exploring a set of residuals. The operational OMI multi-wavelength aerosol retrieval algorithm OMAERO is used for cloud-free, over-land pixels of the OMI instrument with the additional Bayesian model selection and model discrepancy techniques introduced here. The method and improved uncertainty characterisation is demonstrated by several examples with different aerosol properties: weakly absorbing aerosols, forest fires over Greece and Russia, and Sahara desert dust. The statistical methodology presented is general; it is not restricted to this particular satellite retrieval application.
Quotation accuracy in medical journal articles—a systematic review and meta-analysis
Jergas, Hannah
2015-01-01
Background. Quotations and references are an indispensable element of scientific communication. They should support what authors claim or provide important background information for readers. Studies indicate, however, that quotations not serving their purpose—quotation errors—may be prevalent. Methods. We carried out a systematic review, meta-analysis and meta-regression of quotation errors, taking account of differences between studies in error ascertainment. Results. Out of 559 studies screened we included 28 in the main analysis, and estimated major, minor and total quotation error rates of 11,9%, 95% CI [8.4, 16.6] 11.5% [8.3, 15.7], and 25.4% [19.5, 32.4]. While heterogeneity was substantial, even the lowest estimate of total quotation errors was considerable (6.7%). Indirect references accounted for less than one sixth of all quotation problems. The findings remained robust in a number of sensitivity and subgroup analyses (including risk of bias analysis) and in meta-regression. There was no indication of publication bias. Conclusions. Readers of medical journal articles should be aware of the fact that quotation errors are common. Measures against quotation errors include spot checks by editors and reviewers, correct placement of citations in the text, and declarations by authors that they have checked cited material. Future research should elucidate if and to what degree quotation errors are detrimental to scientific progress. PMID:26528420
Applying lessons learned to enhance human performance and reduce human error for ISS operations
DOE Office of Scientific and Technical Information (OSTI.GOV)
Nelson, W.R.
1999-01-01
A major component of reliability, safety, and mission success for space missions is ensuring that the humans involved (flight crew, ground crew, mission control, etc.) perform their tasks and functions as required. This includes compliance with training and procedures during normal conditions, and successful compensation when malfunctions or unexpected conditions occur. A very significant issue that affects human performance in space flight is human error. Human errors can invalidate carefully designed equipment and procedures. If certain errors combine with equipment failures or design flaws, mission failure or loss of life can occur. The control of human error during operation ofmore » the International Space Station (ISS) will be critical to the overall success of the program. As experience from Mir operations has shown, human performance plays a vital role in the success or failure of long duration space missions. The Department of Energy{close_quote}s Idaho National Engineering and Environmental Laboratory (INEEL) is developing a systematic approach to enhance human performance and reduce human errors for ISS operations. This approach is based on the systematic identification and evaluation of lessons learned from past space missions such as Mir to enhance the design and operation of ISS. This paper will describe previous INEEL research on human error sponsored by NASA and how it can be applied to enhance human reliability for ISS. {copyright} {ital 1999 American Institute of Physics.}« less
Applying lessons learned to enhance human performance and reduce human error for ISS operations
DOE Office of Scientific and Technical Information (OSTI.GOV)
Nelson, W.R.
1998-09-01
A major component of reliability, safety, and mission success for space missions is ensuring that the humans involved (flight crew, ground crew, mission control, etc.) perform their tasks and functions as required. This includes compliance with training and procedures during normal conditions, and successful compensation when malfunctions or unexpected conditions occur. A very significant issue that affects human performance in space flight is human error. Human errors can invalidate carefully designed equipment and procedures. If certain errors combine with equipment failures or design flaws, mission failure or loss of life can occur. The control of human error during operation ofmore » the International Space Station (ISS) will be critical to the overall success of the program. As experience from Mir operations has shown, human performance plays a vital role in the success or failure of long duration space missions. The Department of Energy`s Idaho National Engineering and Environmental Laboratory (INEEL) is developed a systematic approach to enhance human performance and reduce human errors for ISS operations. This approach is based on the systematic identification and evaluation of lessons learned from past space missions such as Mir to enhance the design and operation of ISS. This paper describes previous INEEL research on human error sponsored by NASA and how it can be applied to enhance human reliability for ISS.« less
Measuring diagnoses: ICD code accuracy.
O'Malley, Kimberly J; Cook, Karon F; Price, Matt D; Wildes, Kimberly Raiford; Hurdle, John F; Ashton, Carol M
2005-10-01
To examine potential sources of errors at each step of the described inpatient International Classification of Diseases (ICD) coding process. The use of disease codes from the ICD has expanded from classifying morbidity and mortality information for statistical purposes to diverse sets of applications in research, health care policy, and health care finance. By describing a brief history of ICD coding, detailing the process for assigning codes, identifying where errors can be introduced into the process, and reviewing methods for examining code accuracy, we help code users more systematically evaluate code accuracy for their particular applications. We summarize the inpatient ICD diagnostic coding process from patient admission to diagnostic code assignment. We examine potential sources of errors at each step and offer code users a tool for systematically evaluating code accuracy. Main error sources along the "patient trajectory" include amount and quality of information at admission, communication among patients and providers, the clinician's knowledge and experience with the illness, and the clinician's attention to detail. Main error sources along the "paper trail" include variance in the electronic and written records, coder training and experience, facility quality-control efforts, and unintentional and intentional coder errors, such as misspecification, unbundling, and upcoding. By clearly specifying the code assignment process and heightening their awareness of potential error sources, code users can better evaluate the applicability and limitations of codes for their particular situations. ICD codes can then be used in the most appropriate ways.
Sampling errors in blunt dust samplers arising from external wall loss effects
NASA Astrophysics Data System (ADS)
Vincent, J. H.; Gibson, H.
Evidence is given that, with some forms of blunt dust sampler under conditions relating to those encountered in practical occupational hygiene and environmental monitoring, particles which impact onto the outer surface of the sampler body may not adhere permanently, and may eventually enter the sampling orifice. The effect of such external wall loss is to bring about excess sampling, where errors as high as 100% could arise. The problem is particularly important in the sampling of dry airborne particulates of the type commonly found in practical situations. For a given sampler configuration, the effect becomes more marked as the particle size increases or as the ratio of sampling velocity to ambient wind speed increases. We would expect it be greater for gritty, crystalline material than for smoother, amorphous material. Possible mechanisms controlling external wall losses were examined, and it was concluded that particle 'blow-off' (as opposed to particle 'bounce') is the most plausible. On the basis of simple experiments, it might be possible to make corrections for the sampling errors in question, but caution is recommended in doing so because of the unpredictable effects of environmental factors such as temperature and relative humidity. Of the possible practical solutions to the problem, it is felt that the best approach lies in the correct choice of sampler inlet design.
Good practices for quantitative bias analysis.
Lash, Timothy L; Fox, Matthew P; MacLehose, Richard F; Maldonado, George; McCandless, Lawrence C; Greenland, Sander
2014-12-01
Quantitative bias analysis serves several objectives in epidemiological research. First, it provides a quantitative estimate of the direction, magnitude and uncertainty arising from systematic errors. Second, the acts of identifying sources of systematic error, writing down models to quantify them, assigning values to the bias parameters and interpreting the results combat the human tendency towards overconfidence in research results, syntheses and critiques and the inferences that rest upon them. Finally, by suggesting aspects that dominate uncertainty in a particular research result or topic area, bias analysis can guide efficient allocation of sparse research resources. The fundamental methods of bias analyses have been known for decades, and there have been calls for more widespread use for nearly as long. There was a time when some believed that bias analyses were rarely undertaken because the methods were not widely known and because automated computing tools were not readily available to implement the methods. These shortcomings have been largely resolved. We must, therefore, contemplate other barriers to implementation. One possibility is that practitioners avoid the analyses because they lack confidence in the practice of bias analysis. The purpose of this paper is therefore to describe what we view as good practices for applying quantitative bias analysis to epidemiological data, directed towards those familiar with the methods. We focus on answering questions often posed to those of us who advocate incorporation of bias analysis methods into teaching and research. These include the following. When is bias analysis practical and productive? How does one select the biases that ought to be addressed? How does one select a method to model biases? How does one assign values to the parameters of a bias model? How does one present and interpret a bias analysis?. We hope that our guide to good practices for conducting and presenting bias analyses will encourage more widespread use of bias analysis to estimate the potential magnitude and direction of biases, as well as the uncertainty in estimates potentially influenced by the biases. © The Author 2014; all rights reserved. Published by Oxford University Press on behalf of the International Epidemiological Association.
Ko, YuKyung; Yu, Soyoung
2017-09-01
This study was undertaken to explore the correlations among nurses' perceptions of patient safety culture, their intention to report errors, and leader coaching behaviors. The participants (N = 289) were nurses from 5 Korean hospitals with approximately 300 to 500 beds each. Sociodemographic variables, patient safety culture, intention to report errors, and coaching behavior were measured using self-report instruments. Data were analyzed using descriptive statistics, Pearson correlation coefficient, the t test, and the Mann-Whitney U test. Nurses' perceptions of patient safety culture and their intention to report errors showed significant differences between groups of nurses who rated their leaders as high-performing or low-performing coaches. Perceived coaching behavior showed a significant, positive correlation with patient safety culture and intention to report errors, i.e., as nurses' perceptions of coaching behaviors increased, so did their ratings of patient safety culture and error reporting. There is a need in health care settings for coaching by nurse managers to provide quality nursing care and thus improve patient safety. Programs that are systematically developed and implemented to enhance the coaching behaviors of nurse managers are crucial to the improvement of patient safety and nursing care. Moreover, a systematic analysis of the causes of malpractice, as opposed to a focus on the punitive consequences of errors, could increase error reporting and therefore promote a culture in which a higher level of patient safety can thrive.
Influence of ECG measurement accuracy on ECG diagnostic statements.
Zywietz, C; Celikag, D; Joseph, G
1996-01-01
Computer analysis of electrocardiograms (ECGs) provides a large amount of ECG measurement data, which may be used for diagnostic classification and storage in ECG databases. Until now, neither error limits for ECG measurements have been specified nor has their influence on diagnostic statements been systematically investigated. An analytical method is presented to estimate the influence of measurement errors on the accuracy of diagnostic ECG statements. Systematic (offset) errors will usually result in an increase of false positive or false negative statements since they cause a shift of the working point on the receiver operating characteristics curve. Measurement error dispersion broadens the distribution function of discriminative measurement parameters and, therefore, usually increases the overlap between discriminative parameters. This results in a flattening of the receiver operating characteristics curve and an increase of false positive and false negative classifications. The method developed has been applied to ECG conduction defect diagnoses by using the proposed International Electrotechnical Commission's interval measurement tolerance limits. These limits appear too large because more than 30% of false positive atrial conduction defect statements and 10-18% of false intraventricular conduction defect statements could be expected due to tolerated measurement errors. To assure long-term usability of ECG measurement databases, it is recommended that systems provide its error tolerance limits obtained on a defined test set.
Running coupling constant from lattice studies of gluon and ghost propagators
NASA Astrophysics Data System (ADS)
Cucchieri, A.; Mendes, T.
2004-12-01
We present a numerical study of the running coupling constant in four-dimensional pure-SU(2) lattice gauge theory. The running coupling is evaluated by fitting data for the gluon and ghost propagators in minimal Landau gauge. Following Refs. [1, 2], the fitting formulae are obtained by a simultaneous integration of the β function and of a function coinciding with the anomalous dimension of the propagator in the momentum subtraction scheme. We consider these formulae at three and four loops. The fitting method works well, especially for the ghost case, for which statistical error and hyper-cubic effects are very small. Our present result for ΛMS is 200-40+60 MeV, where the error is purely systematic. We are currently extending this analysis to five loops in order to reduce this systematic error.
Simplified model of pinhole imaging for quantifying systematic errors in image shape
DOE Office of Scientific and Technical Information (OSTI.GOV)
Benedetti, Laura Robin; Izumi, N.; Khan, S. F.
In this paper, we examine systematic errors in x-ray imaging by pinhole optics for quantifying uncertainties in the measurement of convergence and asymmetry in inertial confinement fusion implosions. We present a quantitative model for the total resolution of a pinhole optic with an imaging detector that more effectively describes the effect of diffraction than models that treat geometry and diffraction as independent. This model can be used to predict loss of shape detail due to imaging across the transition from geometric to diffractive optics. We find that fractional error in observable shapes is proportional to the total resolution element wemore » present and inversely proportional to the length scale of the asymmetry being observed. Finally, we have experimentally validated our results by imaging a single object with differently sized pinholes and with different magnifications.« less
Simplified model of pinhole imaging for quantifying systematic errors in image shape
Benedetti, Laura Robin; Izumi, N.; Khan, S. F.; ...
2017-10-30
In this paper, we examine systematic errors in x-ray imaging by pinhole optics for quantifying uncertainties in the measurement of convergence and asymmetry in inertial confinement fusion implosions. We present a quantitative model for the total resolution of a pinhole optic with an imaging detector that more effectively describes the effect of diffraction than models that treat geometry and diffraction as independent. This model can be used to predict loss of shape detail due to imaging across the transition from geometric to diffractive optics. We find that fractional error in observable shapes is proportional to the total resolution element wemore » present and inversely proportional to the length scale of the asymmetry being observed. Finally, we have experimentally validated our results by imaging a single object with differently sized pinholes and with different magnifications.« less
NASA Astrophysics Data System (ADS)
Wu, Lifu; Zhu, Jianguo; Xie, Huimin; Zhou, Mengmeng
2016-12-01
Recently, we proposed a single-lens 3D digital image correlation (3D DIC) method and established a measurement system on the basis of a bilateral telecentric lens (BTL) and a bi-prism. This system can retrieve the 3D morphology of a target and measure its deformation using a single BTL with relatively high accuracy. Nevertheless, the system still suffers from systematic errors caused by manufacturing deficiency of the bi-prism and distortion of the BTL. In this study, in-depth evaluations of these errors and their effects on the measurement results are performed experimentally. The bi-prism deficiency and the BTL distortion are characterized by two in-plane rotation angles and several distortion coefficients, respectively. These values are obtained from a calibration process using a chessboard placed into the field of view of the system; this process is conducted after the measurement of tested specimen. A modified mathematical model is proposed, which takes these systematic errors into account and corrects them during 3D reconstruction. Experiments on retrieving the 3D positions of the chessboard grid corners and the morphology of a ceramic plate specimen are performed. The results of the experiments reveal that ignoring the bi-prism deficiency will induce attitude error to the retrieved morphology, and the BTL distortion can lead to its pseudo out-of-plane deformation. Correcting these problems can further improve the measurement accuracy of the bi-prism-based single-lens 3D DIC system.
Systematic review of the evidence for Trails B cut-off scores in assessing fitness-to-drive
Roy, Mononita; Molnar, Frank
2013-01-01
Background Fitness-to-drive guidelines recommend employing the Trail Making B Test (a.k.a. Trails B), but do not provide guidance regarding cut-off scores. There is ongoing debate regarding the optimal cut-off score on the Trails B test. The objective of this study was to address this controversy by systematically reviewing the evidence for specific Trails B cut-off scores (e.g., cut-offs in both time to completion and number of errors) with respect to fitness-to-drive. Methods Systematic review of all prospective cohort, retrospective cohort, case-control, correlation, and cross-sectional studies reporting the ability of the Trails B to predict driving safety that were published in English-language, peer-reviewed journals. Results Forty-seven articles were reviewed. None of the articles justified sample sizes via formal calculations. Cut-off scores reported based on research include: 90 seconds, 133 seconds, 147 seconds, 180 seconds, and < 3 errors. Conclusions There is support for the previously published Trails B cut-offs of 3 minutes or 3 errors (the ‘3 or 3 rule’). Major methodological limitations of this body of research were uncovered including (1) lack of justification of sample size leaving studies open to Type II error (i.e., false negative findings), and (2) excessive focus on associations rather than clinically useful cut-off scores. PMID:23983828
NASA Astrophysics Data System (ADS)
Goh, K. L.; Liew, S. C.; Hasegawa, B. H.
1997-12-01
Computer simulation results from our previous studies showed that energy dependent systematic errors exist in the values of attenuation coefficient synthesized using the basis material decomposition technique with acrylic and aluminum as the basis materials, especially when a high atomic number element (e.g., iodine from radiographic contrast media) was present in the body. The errors were reduced when a basis set was chosen from materials mimicking those found in the phantom. In the present study, we employed a basis material coefficients transformation method to correct for the energy-dependent systematic errors. In this method, the basis material coefficients were first reconstructed using the conventional basis materials (acrylic and aluminum) as the calibration basis set. The coefficients were then numerically transformed to those for a more desirable set materials. The transformation was done at the energies of the low and high energy windows of the X-ray spectrum. With this correction method using acrylic and an iodine-water mixture as our desired basis set, computer simulation results showed that accuracy of better than 2% could be achieved even when iodine was present in the body at a concentration as high as 10% by mass. Simulation work had also been carried out on a more inhomogeneous 2D thorax phantom of the 3D MCAT phantom. The results of the accuracy of quantitation were presented here.
Parametric decadal climate forecast recalibration (DeFoReSt 1.0)
NASA Astrophysics Data System (ADS)
Pasternack, Alexander; Bhend, Jonas; Liniger, Mark A.; Rust, Henning W.; Müller, Wolfgang A.; Ulbrich, Uwe
2018-01-01
Near-term climate predictions such as decadal climate forecasts are increasingly being used to guide adaptation measures. For near-term probabilistic predictions to be useful, systematic errors of the forecasting systems have to be corrected. While methods for the calibration of probabilistic forecasts are readily available, these have to be adapted to the specifics of decadal climate forecasts including the long time horizon of decadal climate forecasts, lead-time-dependent systematic errors (drift) and the errors in the representation of long-term changes and variability. These features are compounded by small ensemble sizes to describe forecast uncertainty and a relatively short period for which typically pairs of reforecasts and observations are available to estimate calibration parameters. We introduce the Decadal Climate Forecast Recalibration Strategy (DeFoReSt), a parametric approach to recalibrate decadal ensemble forecasts that takes the above specifics into account. DeFoReSt optimizes forecast quality as measured by the continuous ranked probability score (CRPS). Using a toy model to generate synthetic forecast observation pairs, we demonstrate the positive effect on forecast quality in situations with pronounced and limited predictability. Finally, we apply DeFoReSt to decadal surface temperature forecasts from the MiKlip prototype system and find consistent, and sometimes considerable, improvements in forecast quality compared with a simple calibration of the lead-time-dependent systematic errors.
On sampling biases arising from insufficient bottle flushing
NASA Astrophysics Data System (ADS)
Codispoti, L. A.; Paver, C. R.
2016-02-01
Collection of representative water samples using carousel bottles is important for accurately determining biological and chemical gradients. The development of more technologically advanced instrumentation and sampling apparatus causes sampling packages to increase and "soak times" to decrease, increasing the probability that insufficient bottle flushing will produce biased results. Qualitative evidence from various expeditions suggest that insufficient flushing may be a problem. Here we report on multiple field experiments that were conducted to better quantify the errors that can arise from insufficient bottle flushing. Our experiments suggest that soak times of more than 2 minutes are sometimes required to collect a representative sample.
How Prediction Errors Shape Perception, Attention, and Motivation
den Ouden, Hanneke E. M.; Kok, Peter; de Lange, Floris P.
2012-01-01
Prediction errors (PE) are a central notion in theoretical models of reinforcement learning, perceptual inference, decision-making and cognition, and prediction error signals have been reported across a wide range of brain regions and experimental paradigms. Here, we will make an attempt to see the forest for the trees and consider the commonalities and differences of reported PE signals in light of recent suggestions that the computation of PE forms a fundamental mode of brain function. We discuss where different types of PE are encoded, how they are generated, and the different functional roles they fulfill. We suggest that while encoding of PE is a common computation across brain regions, the content and function of these error signals can be very different and are determined by the afferent and efferent connections within the neural circuitry in which they arise. PMID:23248610
Blind phase error suppression for color-encoded digital fringe projection profilometry
NASA Astrophysics Data System (ADS)
Ma, S.; Zhu, R.; Quan, C.; Li, B.; Tay, C. J.; Chen, L.
2012-04-01
Color-encoded digital fringe projection profilometry (CDFPP) has the advantage of fast speed, non-contact and full-field testing. It is one of the most important dynamic three-dimensional (3D) profile measurement techniques. However, due to factors such as color cross-talk and gamma distortion of electro-optical devices, phase errors arise when conventional phase-shifting algorithms with fixed phase shift values are utilized to retrieve phases. In this paper, a simple and effective blind phase error suppression approach based on isotropic n-dimensional fringe pattern normalization (INFPN) and carrier squeezing interferometry (CSI) is proposed. It does not require pre-calibration for the gamma and color-coupling coefficients or the phase shift values. Simulation and experimental works show that our proposed approach is able to effectively suppress phase errors and achieve accurate measurement results in CDFPP.
Code of Federal Regulations, 2011 CFR
2011-07-01
... loan defaults as well as from other overpayments of educational assistance benefits) or insurance... services furnished in error (§ 17.101(a) of this chapter). (ii) Debts resulting from services furnished in a medical emergency (§ 17.101(b) of this chapter). (iii) Other claims arising in connection with...
Martín-Rodríguez, Saúl; Loturco, Irineu; Hunter, Angus M; Rodríguez-Ruiz, David; Munguia-Izquierdo, Diego
2017-12-01
Martín-Rodríguez, S, Loturco, I, Hunter, AM, Rodríguez-Ruiz, D, and Munguia-Izquierdo, D. Reliability and measurement error of tensiomyography to assess mechanical muscle function: A systematic review. J Strength Cond Res 31(12): 3524-3536, 2017-Interest in studying mechanical skeletal muscle function through tensiomyography (TMG) has increased in recent years. This systematic review aimed to (a) report the reliability and measurement error of all TMG parameters (i.e., maximum radial displacement of the muscle belly [Dm], contraction time [Tc], delay time [Td], half-relaxation time [½ Tr], and sustained contraction time [Ts]) and (b) to provide critical reflection on how to perform accurate and appropriate measurements for informing clinicians, exercise professionals, and researchers. A comprehensive literature search was performed of the Pubmed, Scopus, Science Direct, and Cochrane databases up to July 2017. Eight studies were included in this systematic review. Meta-analysis could not be performed because of the low quality of the evidence of some studies evaluated. Overall, the review of the 9 studies involving 158 participants revealed high relative reliability (intraclass correlation coefficient [ICC]) for Dm (0.91-0.99); moderate-to-high ICC for Ts (0.80-0.96), Tc (0.70-0.98), and ½ Tr (0.77-0.93); and low-to-high ICC for Td (0.60-0.98), independently of the evaluated muscles. In addition, absolute reliability (coefficient of variation [CV]) was low for all TMG parameters except for ½ Tr (CV = >20%), whereas measurement error indexes were high for this parameter. In conclusion, this study indicates that 3 of the TMG parameters (Dm, Td, and Tc) are highly reliable, whereas ½ Tr demonstrate insufficient reliability, and thus should not be used in future studies.
A proposed method to investigate reliability throughout a questionnaire
2011-01-01
Background Questionnaires are used extensively in medical and health care research and depend on validity and reliability. However, participants may differ in interest and awareness throughout long questionnaires, which can affect reliability of their answers. A method is proposed for "screening" of systematic change in random error, which could assess changed reliability of answers. Methods A simulation study was conducted to explore whether systematic change in reliability, expressed as changed random error, could be assessed using unsupervised classification of subjects by cluster analysis (CA) and estimation of intraclass correlation coefficient (ICC). The method was also applied on a clinical dataset from 753 cardiac patients using the Jalowiec Coping Scale. Results The simulation study showed a relationship between the systematic change in random error throughout a questionnaire and the slope between the estimated ICC for subjects classified by CA and successive items in a questionnaire. This slope was proposed as an awareness measure - to assessing if respondents provide only a random answer or one based on a substantial cognitive effort. Scales from different factor structures of Jalowiec Coping Scale had different effect on this awareness measure. Conclusions Even though assumptions in the simulation study might be limited compared to real datasets, the approach is promising for assessing systematic change in reliability throughout long questionnaires. Results from a clinical dataset indicated that the awareness measure differed between scales. PMID:21974842
NASA Astrophysics Data System (ADS)
Baker, D. F.; Oda, T.; O'Dell, C.; Wunch, D.; Jacobson, A. R.; Yoshida, Y.; Partners, T.
2012-12-01
Measurements of column CO2 concentration from space are now being taken at a spatial and temporal density that permits regional CO2 sources and sinks to be estimated. Systematic errors in the satellite retrievals must be minimized for these estimates to be useful, however. CO2 retrievals from the TANSO instrument aboard the GOSAT satellite are compared to similar column retrievals from the Total Carbon Column Observing Network (TCCON) as the primary method of validation; while this is a powerful approach, it can only be done for overflights of 10-20 locations and has not, for example, permitted validation of GOSAT data over the oceans or deserts. Here we present a complementary approach that uses a global atmospheric transport model and flux inversion method to compare different types of CO2 measurements (GOSAT, TCCON, surface in situ, and aircraft) at different locations, at the cost of added transport error. The measurements from any single type of data are used in a variational carbon data assimilation method to optimize surface CO2 fluxes (with a CarbonTracker prior), then the corresponding optimized CO2 concentration fields are compared to those data types not inverted, using the appropriate vertical weighting. With this approach, we find that GOSAT column CO2 retrievals from the ACOS project (version 2.9 and 2.10) contain systematic errors that make the modeled fit to the independent data worse. However, we find that the differences between the GOSAT data and our prior model are correlated with certain physical variables (aerosol amount, surface albedo, correction to total column mass) that are likely driving errors in the retrievals, independent of CO2 concentration. If we correct the GOSAT data using a fit to these variables, then we find the GOSAT data to improve the fit to independent CO2 data, which suggests that the useful information in the measurements outweighs the negative impact of the remaining systematic errors. With this assurance, we compare the flux estimates given by assimilating the ACOS GOSAT retrievals to similar ones given by NIES GOSAT column retrievals, bias-corrected in a similar manner. Finally, we have found systematic differences on the order of a half ppm between column CO2 integrals from 18 TCCON sites and those given by assimilating NOAA in situ data (both surface and aircraft profile) in this approach. We assess how these differences change in switching to a newer version of the TCCON retrieval software.
Planck 2015 results: VI. LFI mapmaking
Ade, P. A. R.; Aghanim, N.; Ashdown, M.; ...
2016-09-20
This article describes the mapmaking procedure applied to Planck Low Frequency Instrument (LFI) data. The mapmaking step takes as input the calibrated timelines and pointing information. The main products are sky maps of I, Q, and U Stokes components. For the first time, we present polarization maps at LFI frequencies. The mapmaking algorithm is based on a destriping technique, which is enhanced with a noise prior. The Galactic region is masked to reduce errors arising from bandpass mismatch and high signal gradients. We apply horn-uniform radiometer weights to reduce the effects of beam-shape mismatch. The algorithm is the same asmore » used for the 2013 release, apart from small changes in parameter settings. We validate the procedure through simulations. Special emphasis is put on the control of systematics, which is particularly important for accurate polarization analysis. We also produce low-resolution versions of the maps and corresponding noise covariance matrices. These serve as input in later analysis steps and parameter estimation. The noise covariance matrices are validated through noise Monte Carlo simulations. The residual noise in the map products is characterized through analysis of half-ring maps, noise covariance matrices, and simulations.« less
6Li in metal-poor halo stars: real or spurious?
NASA Astrophysics Data System (ADS)
Steffen, M.; Cayrel, R.; Bonifacio, P.; Ludwig, H.-G.; Caffau, E.
2010-03-01
The presence of convective motions in the atmospheres of metal-poor halo stars leads to systematic asymmetries of the emergent spectral line profiles. Since such line asymmetries are very small, they can be safely ignored for standard spectroscopic abundance analysis. However, when it comes to the determination of the 6Li/7Li isotopic ratio, q(Li)=n(6Li)/n(7Li), the intrinsic asymmetry of the 7Li line must be taken into account, because its signature is essentially indistinguishable from the presence of a weak 6Li blend in the red wing of the 7Li line. In this contribution we quantity the error of the inferred 6Li/7Li isotopic ratio that arises if the convective line asymmetry is ignored in the fitting of the λ6707 Å lithium blend. Our conclusion is that 6Li/7Li ratios derived by Asplund et al. (2006), using symmetric line profiles, must be reduced by typically Δq(Li) ≈ 0.015. This diminishes the number of certain 6Li detections from 9 to 4 stars or less, casting some doubt on the existence of a 6Li plateau.
An Advanced N -body Model for Interacting Multiple Stellar Systems
DOE Office of Scientific and Technical Information (OSTI.GOV)
Brož, Miroslav
We construct an advanced model for interacting multiple stellar systems in which we compute all trajectories with a numerical N -body integrator, namely the Bulirsch–Stoer from the SWIFT package. We can then derive various observables: astrometric positions, radial velocities, minima timings (TTVs), eclipse durations, interferometric visibilities, closure phases, synthetic spectra, spectral energy distribution, and even complete light curves. We use a modified version of the Wilson–Devinney code for the latter, in which the instantaneous true phase and inclination of the eclipsing binary are governed by the N -body integration. If all of these types of observations are at one’s disposal,more » a joint χ {sup 2} metric and an optimization algorithm (a simplex or simulated annealing) allow one to search for a global minimum and construct very robust models of stellar systems. At the same time, our N -body model is free from artifacts that may arise if mutual gravitational interactions among all components are not self-consistently accounted for. Finally, we present a number of examples showing dynamical effects that can be studied with our code and we discuss how systematic errors may affect the results (and how to prevent this from happening).« less
Extreme sensitivity in Thermoacoustics
NASA Astrophysics Data System (ADS)
Juniper, Matthew
2017-11-01
In rocket engines and gas turbines, fluctuations in the heat release rate can lock in to acoustic oscillations and grow catastrophically. Nine decades of engine development have shown that these oscillations are difficult to predict but can usually be eliminated with small ad hoc design changes. The difficulty in prediction arises because the oscillations' growth rate is exceedingly sensitive to parameters that cannot always be measured or simulated reliably, which introduces severe systematic error into thermoacoustic models of engines. Passive control strategies then have to be devised through full scale engine tests, which can be ruinously expensive. For the Apollo F1 engine, for example, 2000 full-scale tests were required. Even today, thermoacoustic oscillations often re-appear unexpectedly at full engine test stage. Although the physics is well known, a novel approach to design is required. In this presentation, the parameters of a thermoacoustic model are inferred from many thousand automated experiments using inverse uncertainty quantification. The adjoint of this model is used to obtain cheaply the gradients of every unstable mode with respect to the model parameters. This gradient information is then used in an optimization algorithm to stabilize every thermoacoustic mode by subtly changing the geometry of the model.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Keck, M. L.; Brenneman, L. W.; Ballantyne, D. R.
We present X-ray timing and spectral analyses of simultaneous 150 ks Nuclear Spectroscopic Telescope Array (NuSTAR) and Suzaku X-ray observations of the Seyfert 1.5 galaxy NGC 4151. We disentangle the continuum emission, absorption, and reflection properties of the active galactic nucleus (AGN) by applying inner accretion disk reflection and absorption-dominated models. With a time-averaged spectral analysis, we find strong evidence for relativistic reflection from the inner accretion disk. We find that relativistic emission arises from a highly ionized inner accretion disk with a steep emissivity profile, which suggests an intense, compact illuminating source. We find a preliminary, near-maximal black hole spinmore » $$a\\gt 0.9$$ accounting for statistical and systematic modeling errors. We find a relatively moderate reflection fraction with respect to predictions for the lamp post geometry, in which the illuminating corona is modeled as a point source. Through a time-resolved spectral analysis, we find that modest coronal and inner disk reflection (IDR) flux variation drives the spectral variability during the observations. We discuss various physical scenarios for the IDR model and we find that a compact corona is consistent with the observed features.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhang, Le; Yu, Yu; Zhang, Pengjie, E-mail: lezhang@sjtu.edu.cn
Photo- z error is one of the major sources of systematics degrading the accuracy of weak-lensing cosmological inferences. Zhang et al. proposed a self-calibration method combining galaxy–galaxy correlations and galaxy–shear correlations between different photo- z bins. Fisher matrix analysis shows that it can determine the rate of photo- z outliers at a level of 0.01%–1% merely using photometric data and do not rely on any prior knowledge. In this paper, we develop a new algorithm to implement this method by solving a constrained nonlinear optimization problem arising in the self-calibration process. Based on the techniques of fixed-point iteration and non-negativemore » matrix factorization, the proposed algorithm can efficiently and robustly reconstruct the scattering probabilities between the true- z and photo- z bins. The algorithm has been tested extensively by applying it to mock data from simulated stage IV weak-lensing projects. We find that the algorithm provides a successful recovery of the scatter rates at the level of 0.01%–1%, and the true mean redshifts of photo- z bins at the level of 0.001, which may satisfy the requirements in future lensing surveys.« less
NASA Astrophysics Data System (ADS)
Keck, M. L.; Brenneman, L. W.; Ballantyne, D. R.; Bauer, F.; Boggs, S. E.; Christensen, F. E.; Craig, W. W.; Dauser, T.; Elvis, M.; Fabian, A. C.; Fuerst, F.; García, J.; Grefenstette, B. W.; Hailey, C. J.; Harrison, F. A.; Madejski, G.; Marinucci, A.; Matt, G.; Reynolds, C. S.; Stern, D.; Walton, D. J.; Zoghbi, A.
2015-06-01
We present X-ray timing and spectral analyses of simultaneous 150 ks Nuclear Spectroscopic Telescope Array (NuSTAR) and Suzaku X-ray observations of the Seyfert 1.5 galaxy NGC 4151. We disentangle the continuum emission, absorption, and reflection properties of the active galactic nucleus (AGN) by applying inner accretion disk reflection and absorption-dominated models. With a time-averaged spectral analysis, we find strong evidence for relativistic reflection from the inner accretion disk. We find that relativistic emission arises from a highly ionized inner accretion disk with a steep emissivity profile, which suggests an intense, compact illuminating source. We find a preliminary, near-maximal black hole spin a\\gt 0.9 accounting for statistical and systematic modeling errors. We find a relatively moderate reflection fraction with respect to predictions for the lamp post geometry, in which the illuminating corona is modeled as a point source. Through a time-resolved spectral analysis, we find that modest coronal and inner disk reflection (IDR) flux variation drives the spectral variability during the observations. We discuss various physical scenarios for the IDR model and we find that a compact corona is consistent with the observed features.
Wang, Zhe; Guo, Min; Baker, Gary A.; Stetter, Joseph R.; Lin, Lu; Mason, Andrew J.
2017-01-01
Current sensor devices for the detection of methane or natural gas emission are either expensive and have high power requirements or fail to provide a rapid response. This report describes an electrochemical methane sensor utilizing a non-volatile and conductive pyrrolidinium-based ionic liquid (IL) electrolyte and an innovative internal standard method for methane and oxygen dual-gas detection with high sensitivity, selectivity, and stability. At a platinum electrode in bis(trifluoromethylsulfonyl)imide (NTf2)-based ILs, methane is electro-oxidized to produce CO2 and water when an oxygen reduction process is included. The in situ generated CO2 arising from methane oxidation was shown to provide an excellent internal standard for quantification of the electrochemical oxygen sensor signal. The simultaneous quantification of both methane and oxygen in real time strengthens the reliability of the measurements by cross-validation of two ambient gases occurring within a single sample matrix and allows for the elimination of several types of random and systematic errors in the detection. We have also validated this IL-based methane sensor employing both conventional solid macroelectrodes and flexible microfabricated electrodes using single- and double-potential step chronoamperometry. PMID:25093213
Determination of the number of ψ' events at BESIII
NASA Astrophysics Data System (ADS)
Ablikim, M.; N. Achasov, M.; Albayrak, O.; J. Ambrose, D.; F. An, F.; Q., An; Z. Bai, J.; Ban, Y.; Becker, J.; V. Bennett, J.; Berger, N.; Bertani, M.; M. Bian, J.; Boger, E.; Bondarenko, O.; Boyko, I.; A. Briere, R.; Bytev, V.; Cai, X.; Cakir, O.; Calcaterra, A.; F. Cao, G.; A. Cetin, S.; F. Chang, J.; Chelkov, G.; G., Chen; S. Chen, H.; C. Chen, J.; L. Chen, M.; J. Chen, S.; X., Chen; B. Chen, Y.; P. Cheng, H.; P. Chu, Y.; Cronin-Hennessy, D.; L. Dai, H.; P. Dai, J.; Dedovich, D.; Y. Deng, Z.; Denig, A.; Denysenko, I.; Destefanis, M.; M. Ding, W.; Y., Ding; Y. Dong, L.; Y. Dong, M.; X. Du, S.; J., Fang; S. Fang, S.; Fava, L.; Q. Feng, C.; B. Ferroli, R.; Friedel, P.; D. Fu, C.; Gao, Y.; C., Geng; Goetzen, K.; X. Gong, W.; Gradl, W.; Greco, M.; H. Gu, M.; T. Gu, Y.; H. Guan, Y.; Q. Guo, A.; B. Guo, L.; T., Guo; P. Guo, Y.; L. Han, Y.; A. Harris, F.; L. He, K.; M., He; Y. He, Z.; Held, T.; K. Heng, Y.; L. Hou, Z.; C., Hu; M. Hu, H.; F. Hu, J.; T., Hu; M. Huang, G.; S. Huang, G.; S. Huang, J.; L., Huang; T. Huang, X.; Y., Huang; P. Huang, Y.; Hussain, T.; S. Ji, C.; Q., Ji; P. Ji, Q.; B. Ji, X.; L. Ji, X.; L. Jiang, L.; S. Jiang, X.; B. Jiao, J.; Jiao, Z.; P. Jin, D.; S., Jin; F. Jing, F.; Kalantar-Nayestanaki, N.; Kavatsyuk, M.; Kopf, B.; Kornicer, M.; Kuehn, W.; Lai, W.; S. Lange, J.; Leyhe, M.; H. Li, C.; Cheng, Li; Cui, Li; M. Li, D.; F., Li; G., Li; B. Li, H.; C. Li, J.; K., Li; Lei, Li; J. Li, Q.; L. Li, S.; D. Li, W.; G. Li, W.; L. Li, X.; N. Li, X.; Q. Li, X.; R. Li, X.; B. Li, Z.; H., Liang; F. Liang, Y.; T. Liang, Y.; R. Liao, G.; T. Liao, X.; Lin(Lin, D.; J. Liu, B.; L. Liu, C.; X. Liu, C.; H. Liu, F.; Fang, Liu; Feng, Liu; H., Liu; B. Liu, H.; H. Liu, H.; M. Liu, H.; W. Liu, H.; P. Liu, J.; K., Liu; Y. Liu, K.; Kai, Liu; L. Liu, P.; Q., Liu; B. Liu, S.; X., Liu; B. Liu, Y.; A. Liu, Z.; Zhiqiang, Liu; Zhiqing, Liu; Loehner, H.; R. Lu, G.; J. Lu, H.; G. Lu, J.; W. Lu, Q.; R. Lu, X.; P. Lu, Y.; L. Luo, C.; X. Luo, M.; Luo, T.; L. Luo, X.; Lv, M.; L. Ma, C.; C. Ma, F.; L. Ma, H.; M. Ma, Q.; Ma, S.; Ma, T.; Y. Ma, X.; E. Maas, F.; Maggiora, M.; A. Malik, Q.; J. Mao, Y.; P. Mao, Z.; G. Messchendorp, J.; J., Min; J. Min, T.; E. Mitchell, R.; H. Mo, X.; C. Morales, Morales; Yu. Muchnoi, N.; Muramatsu, H.; Nefedov, Y.; Nicholson, C.; B. Nikolaev, I.; Z., Ning; L. Olsen, S.; Ouyang, Q.; Pacetti, S.; W. Park, J.; Pelizaeus, M.; P. Peng, H.; Peters, K.; L. Ping, J.; G. Ping, R.; Poling, R.; Prencipe, E.; M., Qi; Qian, S.; F. Qiao, C.; Q. Qin, L.; S. Qin, X.; Y., Qin; H. Qin, Z.; F. Qiu, J.; H. Rashid, K.; G., Rong; D. Ruan, X.; Sarantsev, A.; D. Schaefer, B.; Shao, M.; P. Shen, C.; Y. Shen, X.; Y. Sheng, H.; R. Shepherd, M.; Y. Song, X.; Spataro, S.; Spruck, B.; H. Sun, D.; X. Sun, G.; F. Sun, J.; S. Sun, S.; J. Sun, Y.; Z. Sun, Y.; J. Sun, Z.; T. Sun, Z.; J. Tang, C.; Tang, X.; Tapan, I.; H. Thorndike, E.; Toth, D.; Ullrich, M.; S. Varner, G.; Q. Wang, B.; D., Wang; Y. Wang, D.; K., Wang; L. Wang, L.; S. Wang, L.; M., Wang; P., Wang; L. Wang, P.; J. Wang, Q.; G. Wang, S.; F. Wang, X.; L. Wang, X.; F. Wang, Y.; Z., Wang; G. Wang, Z.; Y. Wang, Z.; H. Wei, D.; B. Wei, J.; Weidenkaff, P.; G. Wen, Q.; P. Wen, S.; M., Werner; Wiedner, U.; H. Wu, L.; N., Wu; X. Wu, S.; W., Wu; Z., Wu; G. Xia, L.; X Xia, Y.; J. Xiao, Z.; G. Xie, Y.; L. Xiu, Q.; F. Xu, G.; M. Xu, G.; J. Xu, Q.; N. Xu, Q.; P. Xu, X.; R. Xu, Z.; Xue, F.; Xue, Z.; L., Yan; B. Yan, W.; H. Yan, Y.; X. Yang, H.; Y., Yang; X. Yang, Y.; Ye, H.; Ye, M.; H. Ye, M.; X. Yu, B.; X. Yu, C.; W. Yu, H.; S. Yu, J.; P. Yu, S.; Z. Yuan, C.; Y., Yuan; A. Zafar, A.; Zallo, A.; Zeng, Y.; X. Zhang, B.; Y. Zhang, B.; Zhang, C.; C. Zhang, C.; H. Zhang, D.; H. Zhang, H.; Y. Zhang, H.; Q. Zhang, J.; W. Zhang, J.; Y. Zhang, J.; Z. Zhang, J.; Lili, Zhang; Zhang, R.; H. Zhang, S.; J. Zhang, X.; Y. Zhang, X.; Zhang, Y.; H. Zhang, Y.; P. Zhang, Z.; Y. Zhang, Z.; Zhenghao, Zhang; Zhao, G.; S. Zhao, H.; W. Zhao, J.; X. Zhao, K.; Lei, Zhao; Ling, Zhao; G. Zhao, M.; Zhao, Q.; Z. Zhao, Q.; J. Zhao, S.; C. Zhao, T.; B. Zhao, Y.; G. Zhao, Z.; Zhemchugov, A.; B., Zheng; P. Zheng, J.; H. Zheng, Y.; B., Zhong; Z., Zhong; L., Zhou; K. Zhou, X.; R. Zhou, X.; Zhu, C.; Zhu, K.; J. Zhu, K.; H. Zhu, S.; L. Zhu, X.; C. Zhu, Y.; M. Zhu, Y.; S. Zhu, Y.; A. Zhu, Z.; J., Zhuang; S. Zou, B.; H. Zou, J.
2013-06-01
The number of ψ' events accumulated by the BESIII experiment from March 3 through April 14, 2009, is determined by counting inclusive hadronic events. The result is 106.41×(1.00±0.81%)×106. The error is systematic dominant; the statistical error is negligible.
Improving Student Results in the Crystal Violet Chemical Kinetics Experiment
ERIC Educational Resources Information Center
Kazmierczak, Nathanael; Vander Griend, Douglas A.
2017-01-01
Despite widespread use in general chemistry laboratories, the crystal violet chemical kinetics experiment frequently suffers from erroneous student results. Student calculations for the reaction order in hydroxide often contain large asymmetric errors, pointing to the presence of systematic error. Through a combination of "in silico"…
Theory of Test Translation Error
ERIC Educational Resources Information Center
Solano-Flores, Guillermo; Backhoff, Eduardo; Contreras-Nino, Luis Angel
2009-01-01
In this article, we present a theory of test translation whose intent is to provide the conceptual foundation for effective, systematic work in the process of test translation and test translation review. According to the theory, translation error is multidimensional; it is not simply the consequence of defective translation but an inevitable fact…
Error sources in passive and active microwave satellite soil moisture over Australia
USDA-ARS?s Scientific Manuscript database
Development of a long-term climate record of soil moisture (SM) involves combining historic and present satellite-retrieved SM data sets. This in turn requires a consistent characterization and deep understanding of the systematic differences and errors in the individual data sets, which vary due to...
NASA Astrophysics Data System (ADS)
Bai, Chao-ying; Li, Xing-wang; Wang, Di; Greenhalgh, Stewart
2017-12-01
Earthquake hypocenter determination and traveltime tomography with local earthquake data are normally conducted using a Cartesian coordinate system and assuming a flat Earth model, but for regional and teleseismic data Earth curvature is incorporated and a spherical coordinate system employed. However, when the study region is from the local to near-regional scale (1°-4°), it is unclear what coordinate system to use and what kind of incorrect anomalies or location errors might arise when using the Cartesian coordinate frame. In this paper we investigate in a quantitative sense through two near-regional crustal models and five different inversion methods, the hypocenter errors, reflector perturbation and incorrect velocity anomalies that can arise due to the selection of the wrong coordinate system and inversion method. The simulated inversion results show that the computed traveltime errors are larger than 0.1 s when the epicentral distance exceeds 150 km, and increases linearly with increasing epicentral distance. Such predicted traveltime errors will result in different patterns of incorrect velocity anomalous structures, a perturbed Moho interface for traveltime tomography and source position which deviate for earthquake locations. The maximum magnitude of a velocity image artifact is larger than 1.0% for an epicentral distance of less than 500 km and is up to 0.9% for epicentral distances of less than 300 km. The earthquake source location error is more than 2.0 km for epicentral distances less than 500 km and is up to 1.5 km for epicentral distances less than 300 km. The Moho depth can be in error by up 1.0 km for epicentral distances of less than 500 km but is less than 0.5 km at distances below 300 km. We suggest that spherical coordinate geometry (or time correction) be used whenever there are ray paths at epicentral distances in excess of 150 km.
NASA Technical Reports Server (NTRS)
Hinshaw, G.; Barnes, C.; Bennett, C. L.; Greason, M. R.; Halpern, M.; Hill, R. S.; Jarosik, N.; Kogut, A.; Limon, M.; Meyer, S. S.
2003-01-01
We describe the calibration and data processing methods used to generate full-sky maps of the cosmic microwave background (CMB) from the first year of Wilkinson Microwave Anisotropy Probe (WMAP) observations. Detailed limits on residual systematic errors are assigned based largely on analyses of the flight data supplemented, where necessary, with results from ground tests. The data are calibrated in flight using the dipole modulation of the CMB due to the observatory's motion around the Sun. This constitutes a full-beam calibration source. An iterative algorithm simultaneously fits the time-ordered data to obtain calibration parameters and pixelized sky map temperatures. The noise properties are determined by analyzing the time-ordered data with this sky signal estimate subtracted. Based on this, we apply a pre-whitening filter to the time-ordered data to remove a low level of l/f noise. We infer and correct for a small (approx. 1 %) transmission imbalance between the two sky inputs to each differential radiometer, and we subtract a small sidelobe correction from the 23 GHz (K band) map prior to further analysis. No other systematic error corrections are applied to the data. Calibration and baseline artifacts, including the response to environmental perturbations, are negligible. Systematic uncertainties are comparable to statistical uncertainties in the characterization of the beam response. Both are accounted for in the covariance matrix of the window function and are propagated to uncertainties in the final power spectrum. We characterize the combined upper limits to residual systematic uncertainties through the pixel covariance matrix.
NASA Astrophysics Data System (ADS)
Davis, C.; Rozo, E.; Roodman, A.; Alarcon, A.; Cawthon, R.; Gatti, M.; Lin, H.; Miquel, R.; Rykoff, E. S.; Troxel, M. A.; Vielzeuf, P.; Abbott, T. M. C.; Abdalla, F. B.; Allam, S.; Annis, J.; Bechtol, K.; Benoit-Lévy, A.; Bertin, E.; Brooks, D.; Buckley-Geer, E.; Burke, D. L.; Carnero Rosell, A.; Carrasco Kind, M.; Carretero, J.; Castander, F. J.; Crocce, M.; Cunha, C. E.; D'Andrea, C. B.; da Costa, L. N.; Desai, S.; Diehl, H. T.; Doel, P.; Drlica-Wagner, A.; Fausti Neto, A.; Flaugher, B.; Fosalba, P.; Frieman, J.; García-Bellido, J.; Gaztanaga, E.; Gerdes, D. W.; Giannantonio, T.; Gruen, D.; Gruendl, R. A.; Gutierrez, G.; Honscheid, K.; Jain, B.; James, D. J.; Jeltema, T.; Krause, E.; Kuehn, K.; Kuhlmann, S.; Kuropatkin, N.; Lahav, O.; Li, T. S.; Lima, M.; March, M.; Marshall, J. L.; Martini, P.; Melchior, P.; Ogando, R. L. C.; Plazas, A. A.; Romer, A. K.; Sanchez, E.; Scarpine, V.; Schindler, R.; Schubnell, M.; Sevilla-Noarbe, I.; Smith, M.; Soares-Santos, M.; Sobreira, F.; Suchyta, E.; Swanson, M. E. C.; Tarle, G.; Thomas, D.; Vikram, V.; Walker, A. R.; Wechsler, R. H.
2018-06-01
Galaxy cross-correlations with high-fidelity redshift samples hold the potential to precisely calibrate systematic photometric redshift uncertainties arising from the unavailability of complete and representative training and validation samples of galaxies. However, application of this technique in the Dark Energy Survey (DES) is hampered by the relatively low number density, small area, and modest redshift overlap between photometric and spectroscopic samples. We propose instead using photometric catalogues with reliable photometric redshifts for photo-z calibration via cross-correlations. We verify the viability of our proposal using redMaPPer clusters from the Sloan Digital Sky Survey (SDSS) to successfully recover the redshift distribution of SDSS spectroscopic galaxies. We demonstrate how to combine photo-z with cross-correlation data to calibrate photometric redshift biases while marginalizing over possible clustering bias evolution in either the calibration or unknown photometric samples. We apply our method to DES Science Verification (DES SV) data in order to constrain the photometric redshift distribution of a galaxy sample selected for weak lensing studies, constraining the mean of the tomographic redshift distributions to a statistical uncertainty of Δz ˜ ±0.01. We forecast that our proposal can, in principle, control photometric redshift uncertainties in DES weak lensing experiments at a level near the intrinsic statistical noise of the experiment over the range of redshifts where redMaPPer clusters are available. Our results provide strong motivation to launch a programme to fully characterize the systematic errors from bias evolution and photo-z shapes in our calibration procedure.
Davis, C.; Rozo, E.; Roodman, A.; ...
2018-03-26
Galaxy cross-correlations with high-fidelity redshift samples hold the potential to precisely calibrate systematic photometric redshift uncertainties arising from the unavailability of complete and representative training and validation samples of galaxies. However, application of this technique in the Dark Energy Survey (DES) is hampered by the relatively low number density, small area, and modest redshift overlap between photometric and spectroscopic samples. We propose instead using photometric catalogs with reliable photometric redshifts for photo-z calibration via cross-correlations. We verify the viability of our proposal using redMaPPer clusters from the Sloan Digital Sky Survey (SDSS) to successfully recover the redshift distribution of SDSS spectroscopic galaxies. We demonstrate how to combine photo-z with cross-correlation data to calibrate photometric redshift biases while marginalizing over possible clustering bias evolution in either the calibration or unknown photometric samples. We apply our method to DES Science Verification (DES SV) data in order to constrain the photometric redshift distribution of a galaxy sample selected for weak lensing studies, constraining the mean of the tomographic redshift distributions to a statistical uncertainty ofmore » $$\\Delta z \\sim \\pm 0.01$$. We forecast that our proposal can in principle control photometric redshift uncertainties in DES weak lensing experiments at a level near the intrinsic statistical noise of the experiment over the range of redshifts where redMaPPer clusters are available. Here, our results provide strong motivation to launch a program to fully characterize the systematic errors from bias evolution and photo-z shapes in our calibration procedure.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Davis, C.; Rozo, E.; Roodman, A.
Galaxy cross-correlations with high-fidelity redshift samples hold the potential to precisely calibrate systematic photometric redshift uncertainties arising from the unavailability of complete and representative training and validation samples of galaxies. However, application of this technique in the Dark Energy Survey (DES) is hampered by the relatively low number density, small area, and modest redshift overlap between photometric and spectroscopic samples. We propose instead using photometric catalogs with reliable photometric redshifts for photo-z calibration via cross-correlations. We verify the viability of our proposal using redMaPPer clusters from the Sloan Digital Sky Survey (SDSS) to successfully recover the redshift distribution of SDSS spectroscopic galaxies. We demonstrate how to combine photo-z with cross-correlation data to calibrate photometric redshift biases while marginalizing over possible clustering bias evolution in either the calibration or unknown photometric samples. We apply our method to DES Science Verification (DES SV) data in order to constrain the photometric redshift distribution of a galaxy sample selected for weak lensing studies, constraining the mean of the tomographic redshift distributions to a statistical uncertainty ofmore » $$\\Delta z \\sim \\pm 0.01$$. We forecast that our proposal can in principle control photometric redshift uncertainties in DES weak lensing experiments at a level near the intrinsic statistical noise of the experiment over the range of redshifts where redMaPPer clusters are available. Here, our results provide strong motivation to launch a program to fully characterize the systematic errors from bias evolution and photo-z shapes in our calibration procedure.« less
MERLIN: a Franco-German LIDAR space mission for atmospheric methane
NASA Astrophysics Data System (ADS)
Bousquet, P.; Ehret, G.; Pierangelo, C.; Marshall, J.; Bacour, C.; Chevallier, F.; Gibert, F.; Armante, R.; Crevoisier, C. D.; Edouart, D.; Esteve, F.; Julien, E.; Kiemle, C.; Alpers, M.; Millet, B.
2017-12-01
The Methane Remote Sensing Lidar Mission (MERLIN), currently in phase C, is a joint cooperation between France and Germany on the development, launch and operation of a space LIDAR dedicated to the retrieval of total weighted methane (CH4) atmospheric columns. Atmospheric methane is the second most potent anthropogenic greenhouse gas, contributing 20% to climate radiative forcing but also plying an important role in atmospheric chemistry as a precursor of tropospheric ozone and low-stratosphere water vapour. Its short lifetime ( 9 years) and the nature and variety of its anthropogenic sources also offer interesting mitigation options in regards to the 2° objective of the Paris agreement. For the first time, measurements of atmospheric composition will be performed from space thanks to an IPDA (Integrated Path Differential Absorption) LIDAR (Light Detecting And Ranging), with a precision (target ±27 ppb for a 50km aggregation along the trace) and accuracy (target <3.7 ppb at 68%) sufficient to significantly reduce the uncertainties on methane emissions. The very low targeted systematic error target is particularly ambitious compared to current passive methane space mission. It is achievable because of the differential active measurements of MERLIN, which guarantees almost no contamination by aerosols or water vapour cross-sensitivity. As an active mission, MERLIN will deliver global methane weighted columns (XCH4) for all seasons and all latitudes, day and night Here, we recall the MERLIN objectives and mission characteristics. We also propose an end-to-end error analysis, from the causes of random and systematic errors of the instrument, of the platform and of the data treatment, to the error on methane emissions. To do so, we propose an OSSE analysis (observing system simulation experiment) to estimate the uncertainty reduction on methane emissions brought by MERLIN XCH4. The originality of our inversion system is to transfer both random and systematic errors from the observation space to the flux space, thus providing more realistic error reductions than usually provided in OSSE only using the random part of errors. Uncertainty reductions are presented using two different atmospheric transport models, TM3 and LMDZ, and compared with error reduction achieved with the GOSAT passive mission.
Model parameter-related optimal perturbations and their contributions to El Niño prediction errors
NASA Astrophysics Data System (ADS)
Tao, Ling-Jiang; Gao, Chuan; Zhang, Rong-Hua
2018-04-01
Errors in initial conditions and model parameters (MPs) are the main sources that limit the accuracy of ENSO predictions. In addition to exploring the initial error-induced prediction errors, model errors are equally important in determining prediction performance. In this paper, the MP-related optimal errors that can cause prominent error growth in ENSO predictions are investigated using an intermediate coupled model (ICM) and a conditional nonlinear optimal perturbation (CNOP) approach. Two MPs related to the Bjerknes feedback are considered in the CNOP analysis: one involves the SST-surface wind coupling ({α _τ } ), and the other involves the thermocline effect on the SST ({α _{Te}} ). The MP-related optimal perturbations (denoted as CNOP-P) are found uniformly positive and restrained in a small region: the {α _τ } component is mainly concentrated in the central equatorial Pacific, and the {α _{Te}} component is mainly located in the eastern cold tongue region. This kind of CNOP-P enhances the strength of the Bjerknes feedback and induces an El Niño- or La Niña-like error evolution, resulting in an El Niño-like systematic bias in this model. The CNOP-P is also found to play a role in the spring predictability barrier (SPB) for ENSO predictions. Evidently, such error growth is primarily attributed to MP errors in small areas based on the localized distribution of CNOP-P. Further sensitivity experiments firmly indicate that ENSO simulations are sensitive to the representation of SST-surface wind coupling in the central Pacific and to the thermocline effect in the eastern Pacific in the ICM. These results provide guidance and theoretical support for the future improvement in numerical models to reduce the systematic bias and SPB phenomenon in ENSO predictions.
Human Error and the International Space Station: Challenges and Triumphs in Science Operations
NASA Technical Reports Server (NTRS)
Harris, Samantha S.; Simpson, Beau C.
2016-01-01
Any system with a human component is inherently risky. Studies in human factors and psychology have repeatedly shown that human operators will inevitably make errors, regardless of how well they are trained. Onboard the International Space Station (ISS) where crew time is arguably the most valuable resource, errors by the crew or ground operators can be costly to critical science objectives. Operations experts at the ISS Payload Operations Integration Center (POIC), located at NASA's Marshall Space Flight Center in Huntsville, Alabama, have learned that from payload concept development through execution, there are countless opportunities to introduce errors that can potentially result in costly losses of crew time and science. To effectively address this challenge, we must approach the design, testing, and operation processes with two specific goals in mind. First, a systematic approach to error and human centered design methodology should be implemented to minimize opportunities for user error. Second, we must assume that human errors will be made and enable rapid identification and recoverability when they occur. While a systematic approach and human centered development process can go a long way toward eliminating error, the complete exclusion of operator error is not a reasonable expectation. The ISS environment in particular poses challenging conditions, especially for flight controllers and astronauts. Operating a scientific laboratory 250 miles above the Earth is a complicated and dangerous task with high stakes and a steep learning curve. While human error is a reality that may never be fully eliminated, smart implementation of carefully chosen tools and techniques can go a long way toward minimizing risk and increasing the efficiency of NASA's space science operations.
Guillot, Michel; Gerland, Patrick; Pelletier, François; Saabneh, Ameed
2012-01-01
Background The under-five mortality rate (the probability of dying between birth and age 5 y, also denoted in the literature as U5MR and 5 q 0) is a key indicator of child health, but it conceals important information about how this mortality is distributed by age. One important distinction is what amount of the under-five mortality occurs below age 1 y (1 q 0) versus at age 1 y and above (4 q 1). However, in many country settings, this distinction is often difficult to establish because of various types of data errors. As a result, it is common practice to resort to model age patterns to estimate 1 q 0 and 4 q 1 on the basis of an observed value of 5 q 0. The most commonly used model age patterns for this purpose are the Coale and Demeny and the United Nations systems. Since the development of these models, many additional sources of data for under-five mortality have become available, making possible a general evaluation of age patterns of infant and child mortality. In this paper, we do a systematic comparison of empirical values of 1 q 0 and 4 q 1 against model age patterns, and discuss whether observed deviations are due to data errors, or whether they reflect true epidemiological patterns not addressed in existing model life tables. Methods and Findings We used vital registration data from the Human Mortality Database, sample survey data from the World Fertility Survey and Demographic and Health Surveys programs, and data from Demographic Surveillance Systems. For each of these data sources, we compared empirical combinations of 1 q 0 and 4 q 1 against combinations provided by Coale and Demeny and United Nations model age patterns. We found that, on the whole, empirical values fall relatively well within the range provided by these models, but we also found important exceptions. Sub-Saharan African countries have a tendency to exhibit high values of 4 q 1 relative to 1 q 0, a pattern that appears to arise for the most part from true epidemiological causes. While this pattern is well known in the case of western Africa, we observed that it is more widespread than commonly thought. We also found that the emergence of HIV/AIDS, while perhaps contributing to high relative values of 4 q 1, does not appear to have substantially modified preexisting patterns. We also identified a small number of countries scattered in different parts of the world that exhibit unusually low values of 4 q 1 relative to 1 q 0, a pattern that is not likely to arise merely from data errors. Finally, we illustrate that it is relatively common for populations to experience changes in age patterns of infant and child mortality as they experience a decline in mortality. Conclusions Existing models do not appear to cover the entire range of epidemiological situations and trajectories. Therefore, model life tables should be used with caution for estimating 1 q 0 and 4 q 1 on the basis of 5 q 0. Moreover, this model-based estimation procedure assumes that the input value of 5 q 0 is correct, which may not always be warranted, especially in the case of survey data. A systematic evaluation of data errors in sample surveys and their impact on age patterns of 1 q 0 and 4 q 1 is urgently needed, along with the development of model age patterns of under-five mortality that would cover a wider range of epidemiological situations and trajectories. Please see later in the article for the Editors' Summary. PMID:22952438
Qiao-Grider, Ying; Hung, Li-Fang; Kee, Chea-Su; Ramamirtham, Ramkumar; Smith, Earl L
2010-08-23
We analyzed the contribution of individual ocular components to vision-induced ametropias in 210 rhesus monkeys. The primary contribution to refractive-error development came from vitreous chamber depth; a minor contribution from corneal power was also detected. However, there was no systematic relationship between refractive error and anterior chamber depth or between refractive error and any crystalline lens parameter. Our results are in good agreement with previous studies in humans, suggesting that the refractive errors commonly observed in humans are created by vision-dependent mechanisms that are similar to those operating in monkeys. This concordance emphasizes the applicability of rhesus monkeys in refractive-error studies. Copyright 2010 Elsevier Ltd. All rights reserved.
Qiao-Grider, Ying; Hung, Li-Fang; Kee, Chea-su; Ramamirtham, Ramkumar; Smith, Earl L.
2010-01-01
We analyzed the contribution of individual ocular components to vision-induced ametropias in 210 rhesus monkeys. The primary contribution to refractive-error development came from vitreous chamber depth; a minor contribution from corneal power was also detected. However, there was no systematic relationship between refractive error and anterior chamber depth or between refractive error and any crystalline lens parameter. Our results are in good agreement with previous studies in humans, suggesting that the refractive errors commonly observed in humans are created by vision-dependent mechanisms that are similar to those operating in monkeys. This concordance emphasizes the applicability of rhesus monkeys in refractive-error studies. PMID:20600237
Impact of Non-Gaussian Error Volumes on Conjunction Assessment Risk Analysis
NASA Technical Reports Server (NTRS)
Ghrist, Richard W.; Plakalovic, Dragan
2012-01-01
An understanding of how an initially Gaussian error volume becomes non-Gaussian over time is an important consideration for space-vehicle conjunction assessment. Traditional assumptions applied to the error volume artificially suppress the true non-Gaussian nature of the space-vehicle position uncertainties. For typical conjunction assessment objects, representation of the error volume by a state error covariance matrix in a Cartesian reference frame is a more significant limitation than is the assumption of linearized dynamics for propagating the error volume. In this study, the impact of each assumption is examined and isolated for each point in the volume. Limitations arising from representing the error volume in a Cartesian reference frame is corrected by employing a Monte Carlo approach to probability of collision (Pc), using equinoctial samples from the Cartesian position covariance at the time of closest approach (TCA) between the pair of space objects. A set of actual, higher risk (Pc >= 10 (exp -4)+) conjunction events in various low-Earth orbits using Monte Carlo methods are analyzed. The impact of non-Gaussian error volumes on Pc for these cases is minimal, even when the deviation from a Gaussian distribution is significant.
NASA Technical Reports Server (NTRS)
Muller, Dagmar; Krasemann, Hajo; Brewin, Robert J. W.; Brockmann, Carsten; Deschamps, Pierre-Yves; Fomferra, Norman; Franz, Bryan A.; Grant, Mike G.; Groom, Steve B.; Melin, Frederic;
2015-01-01
The established procedure to access the quality of atmospheric correction processors and their underlying algorithms is the comparison of satellite data products with related in-situ measurements. Although this approach addresses the accuracy of derived geophysical properties in a straight forward fashion, it is also limited in its ability to catch systematic sensor and processor dependent behaviour of satellite products along the scan-line, which might impair the usefulness of the data in spatial analyses. The Ocean Colour Climate Change Initiative (OC-CCI) aims to create an ocean colour dataset on a global scale to meet the demands of the ecosystem modelling community. The need for products with increasing spatial and temporal resolution that also show as little systematic and random errors as possible, increases. Due to cloud cover, even temporal means can be influenced by along-scanline artefacts if the observations are not balanced and effects cannot be cancelled out mutually. These effects can arise from a multitude of results which are not easily separated, if at all. Among the sources of artefacts, there are some sensor-specific calibration issues which should lead to similar responses in all processors, as well as processor-specific features which correspond with the individual choices in the algorithms. A set of methods is proposed and applied to MERIS data over two regions of interest in the North Atlantic and the South Pacific Gyre. The normalised water leaving reflectance products of four atmospheric correction processors, which have also been evaluated in match-up analysis, is analysed in order to find and interpret systematic effects across track. These results are summed up with a semi-objective ranking and are used as a complement to the match-up analysis in the decision for the best Atmospheric Correction (AC) processor. Although the need for discussion remains concerning the absolutes by which to judge an AC processor, this example demonstrates clearly, that relying on the match-up analysis alone can lead to misjudgement.
NASA Astrophysics Data System (ADS)
McKibbin, Seann J.; Ireland, Trevor R.; Amelin, Yuri; Holden, Peter; Sugiura, Naoji
2013-12-01
‘Quenched’ angrite meteorites are among the best time markers of igneous activity in early formed planetesimals of the Solar System. They can be precisely dated by the Mn-Cr extinct nuclide decay system because they contain olivine with high Mn/Cr. Nevertheless, there is disagreement between various determinations of the initial 53Mn/55Mn for this meteorite, hindering their use for cross-calibration between chronometric systems and between Secondary Ion Mass Spectrometry (SIMS) and bulk measurement techniques. Here we re-evaluate the Mn-Cr systematics of olivine from the quenched angrite D’Orbigny using Sensitive High-mass Resolution Ion Micro Probe Reverse Geometry (SHRIMP-RG) to search for heterogeneity in isotope systematics and check for inter-laboratory bias. We investigated possible bias arising due to different data reduction methods and have paid careful attention to the relative sensitivities of Mn and Cr by utilising a three-component mixing model to correct for matrix effects associated with Mg, Fe and Ca zoning in angrite olivine. We have determined an initial 53Mn/55Mn of 3.60 (±0.39) × 10-6 and 3.44 (±0.29) × 10-6 (2σ errors) for D’Orbigny olivine by the Mean of Ratios and Ratio of Total Counts data reduction methods. These values are in agreement with those found by some previous bulk and mineral-scale determinations, and with the generally accepted initial 53Mn/55Mn of this meteorite, but not with previous SIMS work on this material. The source of this discrepancy remains unclear. We can exclude heterogeneity in D’Orbigny as a source of discrepancy because we used the same sample and the meteorite appears to have consistent initial 53Mn/55Mn over both micro- and macro-scales. The discrepancy between this and the previous SIMS study probably reflects an unrecognised systematic analytical bias, possibly associated with relative sensitivities of Mn and Cr or with mass spectrometric backgrounds (isobaric interferences or scattered ions) which may become significant at very low Cr count rates.
A systematic bias in the interpretation of CFI results
Warren E. Frayer
1967-01-01
It is not generally recognized that a serious bias arises in the estimates of annual ingrowth and accretion, two of the growth components available from continuous forest inventory (CFI). The bias is demonstrated, and suggestions for correction are given.
Modelling Drug Administration Regimes for Asthma: A Romanian Experience
ERIC Educational Resources Information Center
Andras, Szilard; Szilagyi, Judit
2010-01-01
In this article, we present a modelling activity, which was a part of the project DQME II (Developing Quality in Mathematics Education, for more details see http://www.dqime.uni-dortmund.de) and some general observations regarding the maladjustments and rational errors arising in such type of activities.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-01
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