Sample records for t213 collaborative irradiation

  1. Half-lives of 221Fr, 217At, 213Bi, 213Po and 209Pb from the 225Ac decay series.

    PubMed

    Suliman, G; Pommé, S; Marouli, M; Van Ammel, R; Stroh, H; Jobbágy, V; Paepen, J; Dirican, A; Bruchertseifer, F; Apostolidis, C; Morgenstern, A

    2013-07-01

    The half-lives of (221)Fr, (217)At, (213)Bi, (213)Po, and (209)Pb were measured by means of an ion-implanted planar Si detector for alpha and beta particles emitted from weak (225)Ac sources or from recoil sources, which were placed in a quasi-2π counting geometry. Recoil sources were prepared by collecting atoms from an open (225)Ac source onto a glass substrate. The (221)Fr and (213)Bi half-lives were determined by following the alpha particle emission rate of recoil sources as a function of time. Similarly, the (209)Pb half-life was determined from the beta particle count rate. The shorter half-lives of (217)At and (213)Po were deduced from delayed coincidence measurements on weak (225)Ac sources using digital data acquisition in list mode. The resulting values: T1/2((221)Fr)=4.806 (6) min, T1/2((217)At)=32.8 (3)ms, T1/2((213)Bi)=45.62 (6)min, T1/2((213)Po)=3.708 (8) μs, and T1/2((209)Pb)=3.232 (5)h were in agreement only with the best literature data. Copyright © 2013 Elsevier Ltd. All rights reserved.

  2. Breaking chemoresistance and radioresistance with [213Bi]anti-CD45 antibodies in leukemia cells.

    PubMed

    Friesen, Claudia; Glatting, Gerhard; Koop, Bernd; Schwarz, Klaus; Morgenstern, Alfred; Apostolidis, Christos; Debatin, Klaus-Michael; Reske, Sven N

    2007-03-01

    Chemoresistance and radioresistance are considered one of the primary reasons for therapeutic failure in leukemias and solid tumors. Targeted radiotherapy using monoclonal antibodies radiolabeled with alpha-particles is a promising treatment approach for high-risk leukemia. We found that targeted radiotherapy using monoclonal CD45 antibodies radiolabeled with the alpha-emitter (213)Bi ([(213)Bi]anti-CD45) induces apoptosis, activates apoptosis pathways, and breaks beta-irradiation-, gamma-irradiation-, doxorubicin-, and apoptosis-resistance in leukemia cells. In contrast to beta-irradiation-, gamma-irradiation-, and doxorubicin-mediated apoptosis and DNA damage, [(213)Bi]anti-CD45-induced DNA damage was not repaired, and apoptosis was not inhibited by the nonhomologous end-joining DNA repair mechanism. Depending on the activation of caspase-3, caspase-8, and caspase-9, [(213)Bi]anti-CD45 activated apoptosis pathways in leukemia cells through the mitochondrial pathway but independent of CD95 receptor/CD95 ligand interaction. Furthermore, [(213)Bi]anti-CD45 reversed deficient activation of caspase-3, caspase-8, and caspase-9, deficient cleavage of poly(ADP-ribose) polymerase, and deficient activation of mitochondria in chemoresistant and in radioresistant and apoptosis-resistant leukemia cells. These findings show that [(213)Bi]anti-CD45 is a promising therapeutic agent to break chemoresistance and radioresistance by overcoming DNA repair mechanisms in leukemia cells and provide the foundation for discovery of novel anticancer compounds.

  3. Evidence for the separate human T-lymphocyte subpopulations that collaborate with autologous monocyte/macrophages in the elaboration of colony-stimulating activity and those that suppress this collaboration.

    PubMed

    Verma, D S; Johnston, D A; McCredie, K B

    1983-11-01

    We investigated the interaction of monocyte/macrophages and autologous T lymphocytes in the methanol extraction residue (MER) of BCG-induced production of granulocyte-macrophage colony-stimulating activity (CSA). Coincubation of monocyte/macrophages and T lymphocytes at a 1:3 ratio produces an optimum collaboration; a change to a 1:9 ratio diminished this collaboration. Coincubation of monocyte/macrophages and T lymphocytes primed with lithium carbonate (2 meq/liter) for 40 hr synergistically increased CSA elaboration and prevented the decline in CSA noted for the 1:9 monocyte/macrophage: T lymphocyte ratio. In contrast, concanavalin-A-primed T lymphocytes did not enhance CSA elaboration at any monocyte/macrophage:T lymphocyte ratio except, occasionally, at 1:9. However, this was overcome if the T lymphocytes were primed with both concanavalin-A and lithium carbonate before their coincubation with monocyte/macrophages. Further cell-mixing experiments revealed that concanavalin-A-primed T lymphocytes contained a subpopulation that suppressed monocyte/macrophage and T-lymphocyte collaboration. Activation of suppressor T lymphocytes could be effectively prevented by lithium carbonate and, in a dose-dependent manner, by irradiation. Also, suppressor T lymphocytes not only diminished the elaboration of colony-stimulating factor(s), but also elaborated an inhibitor of granulocyte-macrophage colony-forming cells. We further demonstrated that the respective hemopoietic helper and suppressor T-lymphocyte activities could be enriched with OKT8- (or OKT4+) and OKT8+ subpopulations.

  4. Development of atherosclerotic-moyamoya syndrome with genetic variant of RNF213 p.R4810K and p.T1727M: A case report.

    PubMed

    Liu, Ying; Wu, Xueying; Fan, Zhaoyang; Cheng, Jingdan; Zhong, Lele; Lin, Yongzhong; Qu, Xiaofeng

    2018-05-01

    We report a rare case of atherosclerotic-moyamoya syndrome (A-MMS) in an adult female with genetic variant of both ring finger 213 (RNF213) p.R4810K and p.T1727M. A 46-year-old previously healthy, right-handed woman displayed transient slurred speech, which started to worsen four years ago. Initial magnetic resonance angiography (MRA) revealed stenosis in left middle cerebral artery (MCA), bilateral anterior cerebral artery (ACA), and left posterior cerebral artery (PCA). The patient subsequently underwent catheter angiography, which confirmed the formation of moyamoya vessels, with Suzuki's angiographic staging of grade-3 on the left side. Although the patient had been on both anti-platelet and statin therapy at the time, a follow-up examination showed further exacerbation of left MCA stenosis, along with enhanced moyamoya vessel formation. On black-blood imaging using DANTE-SPACE, there were eccentric, evolving lesions in the left MCA. We next screened for potential genetic variants, using genomic DNA samples isolated from both the patient and her immediate family members. The results showed that the patient, along with her mother, sister, and brother, possessed the heterozygous variant of the RNF213 gene, including c.14429G > A (p.R4810K) and c.5180C > T (p.T1727M). The patient's daughter did not have the variant. Collectively, we present a unique case of A-MMS with genetic variant of RNF213 p.R4810K and p.T1727M, manifesting as progression. Based on the family tree, these two mutations are on the same RNF213 haplotype. Whether atherosclerosis is the cause of A-MMS or it further exacerbates the injury of MMD to the A-MMS patients with RNF213 gene variant is a question to be investigated. Copyright © 2018. Published by Elsevier B.V.

  5. Verification of the new detection method for irradiated spices based on microbial survival by collaborative blind trial

    NASA Astrophysics Data System (ADS)

    Miyahara, M.; Furuta, M.; Takekawa, T.; Oda, S.; Koshikawa, T.; Akiba, T.; Mori, T.; Mimura, T.; Sawada, C.; Yamaguchi, T.; Nishioka, S.; Tada, M.

    2009-07-01

    An irradiation detection method using the difference of the radiation sensitivity of the heat-treated microorganisms was developed as one of the microbiological detection methods of the irradiated foods. This detection method is based on the difference of the viable cell count before and after heat treatment (70 °C and 10 min). The verification by collaborative blind trial of this method was done by nine inspecting agencies in Japan. The samples used for this trial were five kinds of spices consisting of non-irradiated, 5 kGy irradiated, and 7 kGy irradiated black pepper, allspice, oregano, sage, and paprika, respectively. As a result of this collaboration, a high percentage (80%) of the correct answers was obtained for irradiated black pepper and allspice. However, the method was less successful for irradiated oregano, sage, and paprika. It might be possible to use this detection method for preliminary screening of the irradiated foods but further work is necessary to confirm these findings.

  6. Irradiation properties of T0 chopper components

    NASA Astrophysics Data System (ADS)

    Itoh, Shinichi; Ueno, Kenji; Ohkubo, Ryuji; Sagehashi, Hidenori; Funahashi, Yoshisato; Yokoo, Tetsuya

    2011-10-01

    We investigated the irradiation properties of the components of a T0 chopper. The organic materials in the rotor bearing grease, the magnetic fluids in seals, and the rubber in the timing belt, as well as the semiconductor materials in the rotation sensor and motor encoder, were all irradiated with high-energy γ-rays up to 100 kGy. No significant damage that shortens the lifetime of a T0 chopper was observed for the mechanical components. However, the semiconductor components were damaged by the irradiation. For the rotation sensor system detecting the rotor phase, the signal from a marker on the rotor shaft was transmitted outside the shielding by an optical fiber with radiation-proofing and the electrical circuits were removed from the beamline shielding. The lifetime of the motor encoder possibly meets the requirement for the maintenance period of the T0 chopper.

  7. In Vitro comparison of 213Bi- and 177Lu-radiation for peptide receptor radionuclide therapy.

    PubMed

    Chan, Ho Sze; de Blois, Erik; Morgenstern, Alfred; Bruchertseifer, Frank; de Jong, Marion; Breeman, Wouter; Konijnenberg, Mark

    2017-01-01

    Absorbed doses for α-emitters are different from those for β-emitters, as the high linear energy transfer (LET) nature of α-particles results in a very dense energy deposition over a relatively short path length near the point of emission. This highly localized and therefore high energy deposition can lead to enhanced cell-killing effects at absorbed doses that are non-lethal in low-LET type of exposure. Affinities of DOTA-DPhe1-Tyr3-octreotate (DOTATATE), 115In-DOTATATE, 175Lu-DOTATATE and 209Bi-DOTATATE were determined in the K562-SST2 cell line. Two other cell lines were used for radiation response assessment; BON and CA20948, with a low and high expression of somatostatin receptors, respectively. Cellular uptake kinetics of 111In-DOTATATE were determined in CA20948 cells. CA20948 and BON were irradiated with 137Cs, 177Lu-DTPA, 177Lu-DOTATATE, 213Bi-DTPA and 213Bi-DOTATATE. Absorbed doses were calculated using the MIRDcell dosimetry method for the specific binding and a Monte Carlo model of a cylindrical 6-well plate geometry for the exposure by the radioactive incubation medium. Absorbed doses were compared to conventional irradiation of cells with 137Cs and the relative biological effect (RBE) at 10% survival was calculated. IC50 of (labelled) DOTATATE was in the nM range. Absorbed doses up to 7 Gy were obtained by 5.2 MBq 213Bi-DOTATATE, in majority the dose was caused by α-particle radiation. Cellular internalization determined with 111In-DOTATATE showed a linear relation with incubation time. Cell survival after exposure of 213Bi-DTPA and 213Bi-DOTATATE to BON or CA20948 cells showed a linear-exponential relation with the absorbed dose, confirming the high LET character of 213Bi. The survival of CA20948 after exposure to 177Lu-DOTATATE and the reference 137Cs irradiation showed the typical curvature of the linear-quadratic model. 10% Cell survival of CA20948 was reached at 3 Gy with 213Bi-DOTATATE, a factor 6 lower than the 18 Gy found for 177Lu

  8. In Vitro comparison of 213Bi- and 177Lu-radiation for peptide receptor radionuclide therapy

    PubMed Central

    de Blois, Erik; Morgenstern, Alfred; Bruchertseifer, Frank; de Jong, Marion; Breeman, Wouter; Konijnenberg, Mark

    2017-01-01

    Background Absorbed doses for α-emitters are different from those for β-emitters, as the high linear energy transfer (LET) nature of α-particles results in a very dense energy deposition over a relatively short path length near the point of emission. This highly localized and therefore high energy deposition can lead to enhanced cell-killing effects at absorbed doses that are non-lethal in low-LET type of exposure. Affinities of DOTA-DPhe1-Tyr3-octreotate (DOTATATE), 115In-DOTATATE, 175Lu-DOTATATE and 209Bi-DOTATATE were determined in the K562-SST2 cell line. Two other cell lines were used for radiation response assessment; BON and CA20948, with a low and high expression of somatostatin receptors, respectively. Cellular uptake kinetics of 111In-DOTATATE were determined in CA20948 cells. CA20948 and BON were irradiated with 137Cs, 177Lu-DTPA, 177Lu-DOTATATE, 213Bi-DTPA and 213Bi-DOTATATE. Absorbed doses were calculated using the MIRDcell dosimetry method for the specific binding and a Monte Carlo model of a cylindrical 6-well plate geometry for the exposure by the radioactive incubation medium. Absorbed doses were compared to conventional irradiation of cells with 137Cs and the relative biological effect (RBE) at 10% survival was calculated. Results IC50 of (labelled) DOTATATE was in the nM range. Absorbed doses up to 7 Gy were obtained by 5.2 MBq 213Bi-DOTATATE, in majority the dose was caused by α-particle radiation. Cellular internalization determined with 111In-DOTATATE showed a linear relation with incubation time. Cell survival after exposure of 213Bi-DTPA and 213Bi-DOTATATE to BON or CA20948 cells showed a linear-exponential relation with the absorbed dose, confirming the high LET character of 213Bi. The survival of CA20948 after exposure to 177Lu-DOTATATE and the reference 137Cs irradiation showed the typical curvature of the linear-quadratic model. 10% Cell survival of CA20948 was reached at 3 Gy with 213Bi-DOTATATE, a factor 6 lower than the 18 Gy

  9. Inheritance of a Balanced t(12;20)(q24.33;p12.2) and Unbalanced der(13)t(7;13)(p21.3;q33.2) from a Maternally Derived Double Balanced Translocation Carrier.

    PubMed

    Peterson, Jess F; Geddes, Gabrielle C; Basel, Donald G; Schippman, Dana; Grignon, John W; vanTuinen, Peter; Kappes, Ulrike P

    2018-03-01

    We report a 4-month-old male proband with a history of prominent forehead, hypertelorism, ear abnormalities, micrognathia, hypospadias, and multiple cardiac abnormalities. Initial microarray analysis detected a concurrent 7p21.3-p22.3 duplication and 13q33.2-q34 deletion indicating an unbalanced rearrangement. However, subsequent conventional cytogenetic studies only revealed what appeared to be a balanced t(12;20)(q24.33;p12.2). Fluorescence in situ hybridization (FISH) using chromosome-specific subtelomere probes confirmed the presence of an unbalanced der(13)t(7;13)(p21.3;q33.2) and balanced t(12;20)(q24.33;p12.2), both of maternal origin. In addition to our unique clinical findings, this case highlights the benefits and limitations of both conventional cytogenetic studies and microarray analysis and how FISH complements each methodology.

  10. Effect of irradiation on human T-cell proliferation: low dose irradiation stimulates mitogen-induced proliferation and function of the suppressor/cytotoxic T-cell subset.

    PubMed

    Gualde, N; Goodwin, J S

    1984-04-01

    Unfractionated human T cells exposed to 10-50 rad of X irradiation incorporated less [3H]thymidine than nonirradiated T cells when subsequently cultured with PHA or Con A. The cytotoxic/suppressor T-cell subset, isolated as either OKT8(+) or OKT4(-) cells, demonstrated significantly enhanced [3H]thymidine incorporation in PHA- or Con A-stimulated cultures after exposure to 10-50 rad, compared to unirradiated cells, while the proliferation of the OKT4(+) helper/inducer subset was inhibited by low dose irradiation. It has been previously reported that approximately 30% of the cytotoxic/suppressor subset also stains with OKM1. When the cytotoxic/suppressor subset was further subdivided into OKT4(-), OKM1(+), and OKT4(-), OKM1(-) cells, proliferation of the OKT4(-), OKM1(+) population was inhibited by exposure to 25 rad while proliferation of the OKT4(-), OKM1(-) population was stimulated. The increase in proliferation of the cytotoxic/suppressor T-cell subset after low dose irradiation is paralleled by an increase in suppressor activity of these cells. T cells exposed to 25 rad and then cultured with Con A for 48 hr caused greater inhibition of IgG production when added to fresh autologous lymphocytes stimulated by pokeweed mitogen than did unirradiated cells. Thus, low dose irradiation enhances both the proliferation and function of the human suppressor T-cell subset.

  11. Effect of irradiation on human T-cell proliferation: low dose irradiation stimulates mitogen-induced proliferation and function of the suppressor/cytotoxic T-cell subset

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gualde, N.; Goodwin, J.S.

    1984-04-01

    Unfractionated human T cells exposed to 10-50 rad of X irradiation incorporated less (/sup 3/H)thymidine than nonirradiated T cells when subsequently cultured with PHA or Con A. The cytotoxic/suppressor T-cell subset, isolated as either OKT8(+) or OKT4(-) cells, demonstrated significantly enhanced (/sup 3/H)thymidine incorporation in PHA- or Con A-stimulated cultures after exposure to 10-50 rad, compared to unirradiated cells, while the proliferation of the OKT4(+) helper/inducer subset was inhibited by low dose irradiation. It has been previously reported that approximately 30% of the cytotoxic/suppressor subset also stains with OKM1. When the cytotoxic/suppressor subset was further subdivided into OKT4(-), OKM1(+), andmore » OKT4(-), OKM1(-) cells, proliferation of the OKT4(-), OKM1(+) population was inhibited by exposure to 25 rad while proliferation of the OKT4(-), OKM1(-) population was stimulated. The increase in proliferation of the cytotoxic/suppressor T-cell subset after low dose irradiation is paralleled by an increase in suppressor activity of these cells. T cells exposed to 25 rad and then cultured with Con A for 48 hr caused greater inhibition of IgG production when added to fresh autologous lymphocytes stimulated by pokeweed mitogen than did unirradiated cells. Thus, low dose irradiation enhances both the proliferation and function of the human suppressor T-cell subset.« less

  12. Rescue of CD8+ T cell vaccine memory following sublethal γ irradiation.

    PubMed

    McFarland, Hugh I; Berkson, Julia D; Lee, Jay P; Elkahloun, Abdel G; Mason, Karen P; Rosenberg, Amy S

    2015-07-31

    Sublethal γ irradiation eliminates CD8+ T cell mediated memory responses. In this work, we explored how these memory responses could be rescued in the aftermath of such exposure. We utilized two models of CD8+ T cell mediated immunity: a mouse model of Listeria monocytogenes (LM) infection in which CD8+ T cells specific for LM expressed antigens (Listeriolysin O, LLO) can be tracked, and a murine skin graft model in which CD8+ T cells mediate rejection across a MHC class I (D(d)) disparity. In the LM immunized mice, LL0 specific CD8+ T memory cells were lost on irradiation, preserved with rapid revaccination with an attenuated strain 1-3 days post-irradiation (PI), and these mice survived a subsequent wild type LM challenge. A genetic "signature of rescue" identified a group of immune-associated mRNA maintained or upregulated following irradiation and rescue. A number of these factors, including IL-36γ, dectin-2 (Clec4n), and mir101c are upregulated rapidly after exposure of mice to sublethal γ radiation alone and are sustained by early, but not later rescue. Such factors will be evaluated as potential therapeutics to replace individual vaccines for global rescue of CD8+ T memory cell responses following sublethal γ irradiation. The skin allograft model mirrored that of the LM model in that the accelerated D(d) skin allograft rejection response was lost in mice exposed to sublethal γ radiation, but infusion of allogeneic D(d) expressing bone marrow cells 1-4 days PI preserved the CD8+ T memory mediated accelerated rejection response, further suggesting that innate immune responses may not always be essential to rescue of CD8+ memory T cells following γ irradiation. Published by Elsevier Ltd.

  13. Bismuth 213-labeled anti-CD45 radioimmunoconjugate to condition dogs for nonmyeloablative allogeneic marrow grafts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sandmaier, B M.; Bethge, W A.; Wilbur, D. Scott

    To lower treatment-related mortality and toxicity of conventional marrow transplantation, a nonmyeloablative regimen using 200 cGy total-body irradiation (TBI) and mycophenolate mofetil (MMF) combined with cyclosporine (CSP) for postgrafting immunosuppression was developed. To circumvent possible toxic effects of external- beam gamma irradiation, strategies for targeted radiation therapy were investigated. We tested whether the short-lived (46 minutes) alpha-emitter Bi-213 conjugated to an anti-CD45 monoclonal antibody (mAb) could replace 200 cGy TBI and selectively target hematopoietic tissues in a canine model of nonmyeloablative DLA-identical marrow transplantation. Biodistribution studies using iodine 123-labeled anti-CD45 mAb showed uptake in blood, marrow, lymph nodes, spleen, andmore » liver. In a dose-escalation study, 7 dogs treated with the Bi-213-anti-CD45 conjugate (Bi-213 dose, 0.1-5.9 mCi/kg[3.7-218 MBq/kg]) without marrow grafts had no toxic effects other than a mild, reversible suppression of blood counts. On the basis of these studies, 3 dogs were treated with 0.5 mg/kg Bi-213-labeled anti-CD45 mAb (Bi-213 doses, 3.6, 4.6, and 8.8 mCi/kg[133, 170, and 326 MBq/kg]) given in 6 injections 3 and 2 days before grafting of marrow from DLA-identical littermates. The dogs also received MMF (10 mg/kg subcutaneously twice daily the day of transplantation until day 27 afterward) and CSP (15 mg/kg orally twice daily the day before transplantation until 35 days afterward). Therapy was well tolerated except for transient elevations in levels of transaminases in 3 dogs, followed by, in one dog, ascites. All dogs achieved prompt engraftment and stable mixed hematopoietic chimerism, with donor contributions ranging from 30% to 70% after more than 27 weeks of follow-up. These results form the basis for additional studies in animals and the design of clinical trials using Bi-213 as a nonmyeloablative conditioning regimen with minimal toxicity.« less

  14. Expression of fas protein on CD4+T cells irradiated by low level He-Ne

    NASA Astrophysics Data System (ADS)

    Nie, Fan; Zhu, Jing; Zhang, Hui-Guo

    2005-07-01

    Objective: To investigate the influence on the Expression of Fas protein on CD4+ T cells irradiated by low level He-Ne laser in the cases of psoriasis. Methods:the expression of CD4+ T Fas protein was determined in the casee of psoriasis(n=5) pre and post-low level laser irradiation(30 min、60min and 120min)by flow cytometry as compared withthe control(n=5). Results:In the cases of psoriasis,the expression of CD4+T FAS protein 21.4+/-3.1% was increased significantly than that of control group 16.8+/-2.1% pre-irradiation, p<0.05in the control,there is no difference between pre and post- irradiation,p>0.05in the cases , the expression of CD4+T Fas protein wae positively corelated to the irradiation times, when the energy density arrived to 22.92J/cm2（60 minutes）and 45.84J/cm2（120minutes）, the expression of CD4+ T Fas protein was increased significantly as compared with pre-irradiation,p<0.05.Conclusion: The expression of CD4+T Fas protein may be increased by low level He-Ne laser irradiation ,the uncontrolled status of apoptosis could be corrected.

  15. 47 CFR 76.213 - Lotteries.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 4 2011-10-01 2011-10-01 false Lotteries. 76.213 Section 76.213 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Cablecasting § 76.213 Lotteries. (a) No cable television system operator...

  16. 47 CFR 76.213 - Lotteries.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 4 2014-10-01 2014-10-01 false Lotteries. 76.213 Section 76.213 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Cablecasting § 76.213 Lotteries. (a) No cable television system operator...

  17. 47 CFR 76.213 - Lotteries.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Lotteries. 76.213 Section 76.213 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Cablecasting § 76.213 Lotteries. (a) No cable television system operator...

  18. 47 CFR 76.213 - Lotteries.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 4 2013-10-01 2013-10-01 false Lotteries. 76.213 Section 76.213 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Cablecasting § 76.213 Lotteries. (a) No cable television system operator...

  19. 47 CFR 76.213 - Lotteries.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 4 2012-10-01 2012-10-01 false Lotteries. 76.213 Section 76.213 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Cablecasting § 76.213 Lotteries. (a) No cable television system operator...

  20. 47 CFR 213.4 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Definitions. 213.4 Section 213.4 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.4 Definitions. As used herein: (a) Public...

  1. 47 CFR 213.4 - Definitions.

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  2. 47 CFR 213.3 - Cancellation.

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    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Cancellation. 213.3 Section 213.3 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.3 Cancellation. This circular cancels: (a) Attachments...

  3. 47 CFR 213.3 - Cancellation.

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    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Cancellation. 213.3 Section 213.3 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.3 Cancellation. This circular cancels: (a) Attachments...

  4. 47 CFR 213.3 - Cancellation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Cancellation. 213.3 Section 213.3 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.3 Cancellation. This circular cancels: (a) Attachments...

  5. 47 CFR 213.8 - Implementation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Implementation. 213.8 Section 213.8 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.8 Implementation. Federal departments and agencies are...

  6. 47 CFR 213.4 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Definitions. 213.4 Section 213.4 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.4 Definitions. As used herein: (a) Public...

  7. 47 CFR 213.4 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Definitions. 213.4 Section 213.4 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.4 Definitions. As used herein: (a) Public...

  8. 47 CFR 213.8 - Implementation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Implementation. 213.8 Section 213.8 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.8 Implementation. Federal departments and agencies are...

  9. 47 CFR 213.3 - Cancellation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Cancellation. 213.3 Section 213.3 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.3 Cancellation. This circular cancels: (a) Attachments...

  10. 47 CFR 213.8 - Implementation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Implementation. 213.8 Section 213.8 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.8 Implementation. Federal departments and agencies are...

  11. 47 CFR 213.8 - Implementation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Implementation. 213.8 Section 213.8 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.8 Implementation. Federal departments and agencies are...

  12. 47 CFR 213.4 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Definitions. 213.4 Section 213.4 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.4 Definitions. As used herein: (a) Public...

  13. 47 CFR 213.3 - Cancellation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Cancellation. 213.3 Section 213.3 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.3 Cancellation. This circular cancels: (a) Attachments...

  14. 47 CFR 213.8 - Implementation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Implementation. 213.8 Section 213.8 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.8 Implementation. Federal departments and agencies are...

  15. 49 CFR 213.55 - Alinement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Alinement. 213.55 Section 213.55 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION TRACK SAFETY STANDARDS Track Geometry § 213.55 Alinement. Alinement may not deviate from...

  16. 49 CFR 213.55 - Alinement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Alinement. 213.55 Section 213.55 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION TRACK SAFETY STANDARDS Track Geometry § 213.55 Alinement. Alinement may not deviate from...

  17. 47 CFR 213.2 - Scope.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Scope. 213.2 Section 213.2 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.2 Scope. The precedence system contained herein is...

  18. 47 CFR 213.7 - Policies.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Policies. 213.7 Section 213.7 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.7 Policies. (a) Calls and messages in each precedence...

  19. 47 CFR 213.0 - Authority.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Authority. 213.0 Section 213.0 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.0 Authority. (a) The voice and message precedence...

  20. 47 CFR 213.7 - Policies.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Policies. 213.7 Section 213.7 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.7 Policies. (a) Calls and messages in each precedence...

  1. 47 CFR 213.2 - Scope.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Scope. 213.2 Section 213.2 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.2 Scope. The precedence system contained herein is...

  2. 47 CFR 213.2 - Scope.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Scope. 213.2 Section 213.2 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.2 Scope. The precedence system contained herein is...

  3. 47 CFR 213.7 - Policies.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Policies. 213.7 Section 213.7 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.7 Policies. (a) Calls and messages in each precedence...

  4. 47 CFR 213.0 - Authority.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Authority. 213.0 Section 213.0 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.0 Authority. (a) The voice and message precedence...

  5. 47 CFR 213.2 - Scope.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Scope. 213.2 Section 213.2 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.2 Scope. The precedence system contained herein is...

  6. 47 CFR 213.0 - Authority.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Authority. 213.0 Section 213.0 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.0 Authority. (a) The voice and message precedence...

  7. 47 CFR 213.7 - Policies.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Policies. 213.7 Section 213.7 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.7 Policies. (a) Calls and messages in each precedence...

  8. 47 CFR 213.0 - Authority.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Authority. 213.0 Section 213.0 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.0 Authority. (a) The voice and message precedence...

  9. 47 CFR 213.0 - Authority.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Authority. 213.0 Section 213.0 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.0 Authority. (a) The voice and message precedence...

  10. 47 CFR 213.7 - Policies.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Policies. 213.7 Section 213.7 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.7 Policies. (a) Calls and messages in each precedence...

  11. 47 CFR 213.2 - Scope.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Scope. 213.2 Section 213.2 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.2 Scope. The precedence system contained herein is...

  12. 49 CFR 213.51 - Scope.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Scope. 213.51 Section 213.51 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION TRACK SAFETY STANDARDS Track Geometry § 213.51 Scope. This subpart prescribes requirements for the...

  13. 49 CFR 213.51 - Scope.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Scope. 213.51 Section 213.51 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION TRACK SAFETY STANDARDS Track Geometry § 213.51 Scope. This subpart prescribes requirements for the...

  14. 42 CFR 59.213 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false [Reserved] 59.213 Section 59.213 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR FAMILY PLANNING SERVICES Grants for Family Planning Service Training § 59.213 [Reserved] ...

  15. 42 CFR 59.213 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false [Reserved] 59.213 Section 59.213 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR FAMILY PLANNING SERVICES Grants for Family Planning Service Training § 59.213 [Reserved] ...

  16. 42 CFR 59.213 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false [Reserved] 59.213 Section 59.213 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR FAMILY PLANNING SERVICES Grants for Family Planning Service Training § 59.213 [Reserved] ...

  17. 42 CFR 59.213 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false [Reserved] 59.213 Section 59.213 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR FAMILY PLANNING SERVICES Grants for Family Planning Service Training § 59.213 [Reserved] ...

  18. 42 CFR 59.213 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false [Reserved] 59.213 Section 59.213 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR FAMILY PLANNING SERVICES Grants for Family Planning Service Training § 59.213 [Reserved] ...

  19. 49 CFR 1542.213 - Training.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Training. 1542.213 Section 1542.213 Transportation..., DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY Operations § 1542.213 Training. (a... training in accordance with TSA-approved curriculum specified in the security program. This curriculum must...

  20. 47 CFR 213.6 - Criteria.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Criteria. 213.6 Section 213.6 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.6 Criteria. (a) Flash, Flash Emergency. (1) This is the...

  1. 47 CFR 213.6 - Criteria.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Criteria. 213.6 Section 213.6 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.6 Criteria. (a) Flash, Flash Emergency. (1) This is the...

  2. 47 CFR 213.6 - Criteria.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Criteria. 213.6 Section 213.6 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.6 Criteria. (a) Flash, Flash Emergency. (1) This is the...

  3. 47 CFR 213.6 - Criteria.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Criteria. 213.6 Section 213.6 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.6 Criteria. (a) Flash, Flash Emergency. (1) This is the...

  4. 47 CFR 213.6 - Criteria.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Criteria. 213.6 Section 213.6 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.6 Criteria. (a) Flash, Flash Emergency. (1) This is the...

  5. 49 CFR 213.53 - Gage.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Gage. 213.53 Section 213.53 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION TRACK SAFETY STANDARDS Track Geometry § 213.53 Gage. (a) Gage is measured between the heads of the...

  6. 49 CFR 213.53 - Gage.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Gage. 213.53 Section 213.53 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION TRACK SAFETY STANDARDS Track Geometry § 213.53 Gage. (a) Gage is measured between the heads of the...

  7. 14 CFR 213.6 - Compliance.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Compliance. 213.6 Section 213.6 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS TERMS, CONDITIONS AND LIMITATIONS OF FOREIGN AIR CARRIER PERMITS § 213.6 Compliance. Any violation...

  8. 14 CFR 213.6 - Compliance.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Compliance. 213.6 Section 213.6 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS TERMS, CONDITIONS AND LIMITATIONS OF FOREIGN AIR CARRIER PERMITS § 213.6 Compliance. Any violation...

  9. 15 CFR 904.213 - Settlements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Settlements. 904.213 Section 904.213 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) NATIONAL OCEANIC... and Appeal Procedures General § 904.213 Settlements. If settlement is reached before the Judge has...

  10. 14 CFR 16.213 - Discovery.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Discovery. 16.213 Section 16.213... PRACTICE FOR FEDERALLY-ASSISTED AIRPORT ENFORCEMENT PROCEEDINGS Hearings § 16.213 Discovery. (a) Discovery... discovery permitted by this section if a party shows that— (1) The information requested is cumulative or...

  11. 14 CFR 16.213 - Discovery.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Discovery. 16.213 Section 16.213... PRACTICE FOR FEDERALLY-ASSISTED AIRPORT ENFORCEMENT PROCEEDINGS Hearings § 16.213 Discovery. (a) Discovery... discovery permitted by this section if a party shows that— (1) The information requested is cumulative or...

  12. 14 CFR 16.213 - Discovery.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Discovery. 16.213 Section 16.213... PRACTICE FOR FEDERALLY-ASSISTED AIRPORT ENFORCEMENT PROCEEDINGS Hearings § 16.213 Discovery. (a) Discovery... discovery permitted by this section if a party shows that— (1) The information requested is cumulative or...

  13. 14 CFR 16.213 - Discovery.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Discovery. 16.213 Section 16.213... PRACTICE FOR FEDERALLY-ASSISTED AIRPORT ENFORCEMENT PROCEEDINGS Hearings § 16.213 Discovery. (a) Discovery... discovery permitted by this section if a party shows that— (1) The information requested is cumulative or...

  14. 22 CFR 213.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... garnishment means the process by which federal agencies require a private sector employer to withhold up to 15... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Definitions. 213.2 Section 213.2 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT CLAIMS COLLECTION General § 213.2 Definitions. (a...

  15. 14 CFR 16.213 - Discovery.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Discovery. 16.213 Section 16.213... PRACTICE FOR FEDERALLY-ASSISTED AIRPORT ENFORCEMENT PROCEEDINGS Hearings § 16.213 Discovery. (a) Discovery... discovery permitted by this section if a party shows that— (1) The information requested is cumulative or...

  16. 27 CFR 28.213 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false [Reserved] 28.213 Section 28.213 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS EXPORTATION OF ALCOHOL Exportation of Wine With Benefit of Drawback § 28.213...

  17. 36 CFR 2.13 - Fires.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Fires. 2.13 Section 2.13 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR RESOURCE PROTECTION, PUBLIC USE AND RECREATION § 2.13 Fires. (a) The following are prohibited: (1) Lighting or...

  18. 14 CFR 171.213 - Reports.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Reports. 171.213 Section 171.213... FACILITIES NON-FEDERAL NAVIGATION FACILITIES VHF Marker Beacons § 171.213 Reports. The owner of each facility to which this subpart applies shall make the following reports, at the times indicated, to the...

  19. 14 CFR 171.213 - Reports.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Reports. 171.213 Section 171.213... FACILITIES NON-FEDERAL NAVIGATION FACILITIES VHF Marker Beacons § 171.213 Reports. The owner of each facility to which this subpart applies shall make the following reports, at the times indicated, to the...

  20. 14 CFR 171.213 - Reports.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Reports. 171.213 Section 171.213... FACILITIES NON-FEDERAL NAVIGATION FACILITIES VHF Marker Beacons § 171.213 Reports. The owner of each facility to which this subpart applies shall make the following reports, at the times indicated, to the...

  1. 49 CFR 213.135 - Switches.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Switches. 213.135 Section 213.135 Transportation... TRANSPORTATION TRACK SAFETY STANDARDS Track Structure § 213.135 Switches. (a) Each stock rail must be securely seated in switch plates, but care shall be used to avoid canting the rail by overtightening the rail...

  2. 49 CFR 213.135 - Switches.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Switches. 213.135 Section 213.135 Transportation... TRANSPORTATION TRACK SAFETY STANDARDS Track Structure § 213.135 Switches. (a) Each stock rail must be securely seated in switch plates, but care shall be used to avoid canting the rail by overtightening the rail...

  3. 49 CFR 213.135 - Switches.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Switches. 213.135 Section 213.135 Transportation... TRANSPORTATION TRACK SAFETY STANDARDS Track Structure § 213.135 Switches. (a) Each stock rail must be securely seated in switch plates, but care shall be used to avoid canting the rail by overtightening the rail...

  4. 49 CFR 213.15 - Penalties.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Penalties. 213.15 Section 213.15 Transportation... TRANSPORTATION TRACK SAFETY STANDARDS General § 213.15 Penalties. (a) Any person who violates any requirement of this part or causes the violation of any such requirement is subject to a civil penalty of at least...

  5. 49 CFR 213.15 - Penalties.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Penalties. 213.15 Section 213.15 Transportation... TRANSPORTATION TRACK SAFETY STANDARDS General § 213.15 Penalties. (a) Any person who violates any requirement of this part or causes the violation of any such requirement is subject to a civil penalty of at least...

  6. 49 CFR 213.15 - Penalties.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Penalties. 213.15 Section 213.15 Transportation... TRANSPORTATION TRACK SAFETY STANDARDS General § 213.15 Penalties. (a) Any person who violates any requirement of this part or causes the violation of any such requirement is subject to a civil penalty of at least...

  7. 49 CFR 213.15 - Penalties.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Penalties. 213.15 Section 213.15 Transportation... TRANSPORTATION TRACK SAFETY STANDARDS General § 213.15 Penalties. (a) Any person who violates any requirement of this part or causes the violation of any such requirement is subject to a civil penalty of at least...

  8. 49 CFR 213.15 - Penalties.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Penalties. 213.15 Section 213.15 Transportation... TRANSPORTATION TRACK SAFETY STANDARDS General § 213.15 Penalties. (a) Any person who violates any requirement of this part or causes the violation of any such requirement is subject to a civil penalty of at least...

  9. 28 CFR 21.3 - Aliens.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Aliens. 21.3 Section 21.3 Judicial Administration DEPARTMENT OF JUSTICE WITNESS FEES § 21.3 Aliens. (a) Aliens entitled to payment of $30 per day. The following aliens are entitled to witness fees and allowances provided in § 21.4: (1) Aliens...

  10. 28 CFR 21.3 - Aliens.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Aliens. 21.3 Section 21.3 Judicial Administration DEPARTMENT OF JUSTICE WITNESS FEES § 21.3 Aliens. (a) Aliens entitled to payment of $30 per day. The following aliens are entitled to witness fees and allowances provided in § 21.4: (1) Aliens...

  11. 28 CFR 21.3 - Aliens.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Aliens. 21.3 Section 21.3 Judicial Administration DEPARTMENT OF JUSTICE WITNESS FEES § 21.3 Aliens. (a) Aliens entitled to payment of $30 per day. The following aliens are entitled to witness fees and allowances provided in § 21.4: (1) Aliens...

  12. 28 CFR 21.3 - Aliens.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Aliens. 21.3 Section 21.3 Judicial Administration DEPARTMENT OF JUSTICE WITNESS FEES § 21.3 Aliens. (a) Aliens entitled to payment of $30 per day. The following aliens are entitled to witness fees and allowances provided in § 21.4: (1) Aliens...

  13. 28 CFR 21.3 - Aliens.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Aliens. 21.3 Section 21.3 Judicial Administration DEPARTMENT OF JUSTICE WITNESS FEES § 21.3 Aliens. (a) Aliens entitled to payment of $30 per day. The following aliens are entitled to witness fees and allowances provided in § 21.4: (1) Aliens...

  14. 36 CFR 2.13 - Fires.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Fires. 2.13 Section 2.13... PROTECTION, PUBLIC USE AND RECREATION § 2.13 Fires. (a) The following are prohibited: (1) Lighting or maintaining a fire, except in designated areas or receptacles and under conditions that may be established by...

  15. 13 CFR 134.213 - Discovery.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Discovery. 134.213 Section 134.213... OFFICE OF HEARINGS AND APPEALS Rules of Practice for Most Cases § 134.213 Discovery. (a) Motion. A party may obtain discovery only upon motion, and for good cause shown. (b) Forms. The forms of discovery...

  16. 12 CFR 213.7 - Advertising.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 2 2013-01-01 2013-01-01 false Advertising. 213.7 Section 213.7 Banks and... (REGULATION M) § 213.7 Advertising. (a) General rule. An advertisement for a consumer lease may state that a... paragraph (d)(1) of this section shall also state the following items: (i) That the transaction advertised...

  17. 12 CFR 213.7 - Advertising.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 2 2011-01-01 2011-01-01 false Advertising. 213.7 Section 213.7 Banks and... (REGULATION M) § 213.7 Advertising. (a) General rule. An advertisement for a consumer lease may state that a... paragraph (d)(1) of this section shall also state the following items: (i) That the transaction advertised...

  18. 12 CFR 213.7 - Advertising.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Advertising. 213.7 Section 213.7 Banks and... (REGULATION M) § 213.7 Advertising. (a) General rule. An advertisement for a consumer lease may state that a... paragraph (d)(1) of this section shall also state the following items: (i) That the transaction advertised...

  19. 12 CFR 213.7 - Advertising.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 2 2012-01-01 2012-01-01 false Advertising. 213.7 Section 213.7 Banks and... (REGULATION M) § 213.7 Advertising. (a) General rule. An advertisement for a consumer lease may state that a... paragraph (d)(1) of this section shall also state the following items: (i) That the transaction advertised...

  20. 12 CFR 213.7 - Advertising.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 2 2014-01-01 2014-01-01 false Advertising. 213.7 Section 213.7 Banks and... (REGULATION M) § 213.7 Advertising. (a) General rule. An advertisement for a consumer lease may state that a... paragraph (d)(1) of this section shall also state the following items: (i) That the transaction advertised...

  1. 13 CFR 134.213 - Discovery.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 13 Business Credit and Assistance 1 2014-01-01 2014-01-01 false Discovery. 134.213 Section 134.213... OFFICE OF HEARINGS AND APPEALS Rules of Practice § 134.213 Discovery. (a) Motion. A party may obtain discovery only upon motion, and for good cause shown. (b) Forms. The forms of discovery which a Judge can...

  2. 13 CFR 134.213 - Discovery.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 13 Business Credit and Assistance 1 2013-01-01 2013-01-01 false Discovery. 134.213 Section 134.213... OFFICE OF HEARINGS AND APPEALS Rules of Practice § 134.213 Discovery. (a) Motion. A party may obtain discovery only upon motion, and for good cause shown. (b) Forms. The forms of discovery which a Judge can...

  3. 13 CFR 134.213 - Discovery.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 13 Business Credit and Assistance 1 2011-01-01 2011-01-01 false Discovery. 134.213 Section 134.213... OFFICE OF HEARINGS AND APPEALS Rules of Practice § 134.213 Discovery. (a) Motion. A party may obtain discovery only upon motion, and for good cause shown. (b) Forms. The forms of discovery which a Judge can...

  4. 13 CFR 134.213 - Discovery.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 13 Business Credit and Assistance 1 2012-01-01 2012-01-01 false Discovery. 134.213 Section 134.213... OFFICE OF HEARINGS AND APPEALS Rules of Practice § 134.213 Discovery. (a) Motion. A party may obtain discovery only upon motion, and for good cause shown. (b) Forms. The forms of discovery which a Judge can...

  5. 25 CFR 213.32 - Wells.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Wells. 213.32 Section 213.32 Indians BUREAU OF INDIAN... CIVILIZED TRIBES, OKLAHOMA, FOR MINING Operations § 213.32 Wells. The lessee shall agree (a) to drill and produce all wells necessary to offset or protect the leased land from drainage by wells on adjoining lands...

  6. 25 CFR 213.32 - Wells.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Wells. 213.32 Section 213.32 Indians BUREAU OF INDIAN... CIVILIZED TRIBES, OKLAHOMA, FOR MINING Operations § 213.32 Wells. The lessee shall agree (a) to drill and produce all wells necessary to offset or protect the leased land from drainage by wells on adjoining lands...

  7. 25 CFR 213.32 - Wells.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Wells. 213.32 Section 213.32 Indians BUREAU OF INDIAN... CIVILIZED TRIBES, OKLAHOMA, FOR MINING Operations § 213.32 Wells. The lessee shall agree (a) to drill and produce all wells necessary to offset or protect the leased land from drainage by wells on adjoining lands...

  8. 25 CFR 213.32 - Wells.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Wells. 213.32 Section 213.32 Indians BUREAU OF INDIAN... CIVILIZED TRIBES, OKLAHOMA, FOR MINING Operations § 213.32 Wells. The lessee shall agree (a) to drill and produce all wells necessary to offset or protect the leased land from drainage by wells on adjoining lands...

  9. 25 CFR 213.32 - Wells.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Wells. 213.32 Section 213.32 Indians BUREAU OF INDIAN... CIVILIZED TRIBES, OKLAHOMA, FOR MINING Operations § 213.32 Wells. The lessee shall agree (a) to drill and produce all wells necessary to offset or protect the leased land from drainage by wells on adjoining lands...

  10. 48 CFR 213.302 - Purchase orders.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Purchase orders. 213.302 Section 213.302 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... Acquisition Methods 213.302 Purchase orders. ...

  11. 47 CFR 101.213 - Station identification.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Station identification. 101.213 Section 101.213 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Operational Requirements § 101.213 Station identification. Stations in these services are exempt...

  12. 47 CFR 101.213 - Station identification.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Station identification. 101.213 Section 101.213 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Operational Requirements § 101.213 Station identification. Stations in these services are exempt...

  13. 47 CFR 101.213 - Station identification.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Station identification. 101.213 Section 101.213 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Operational Requirements § 101.213 Station identification. Stations in these services are exempt...

  14. 47 CFR 101.213 - Station identification.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Station identification. 101.213 Section 101.213 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Operational Requirements § 101.213 Station identification. Stations in these services are exempt...

  15. 47 CFR 101.213 - Station identification.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Station identification. 101.213 Section 101.213 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Operational Requirements § 101.213 Station identification. Stations in these services are exempt...

  16. 49 CFR 213.2 - Preemptive effect.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Preemptive effect. 213.2 Section 213.2 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION TRACK SAFETY STANDARDS General § 213.2 Preemptive effect. Under 49 U.S.C. 20106...

  17. 47 CFR 213.5 - Precedence designators.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Precedence designators. 213.5 Section 213.5 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.5 Precedence designators. (a) The following precedence...

  18. 47 CFR 213.5 - Precedence designators.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Precedence designators. 213.5 Section 213.5 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.5 Precedence designators. (a) The following precedence...

  19. 47 CFR 213.5 - Precedence designators.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Precedence designators. 213.5 Section 213.5 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.5 Precedence designators. (a) The following precedence...

  20. 47 CFR 213.5 - Precedence designators.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Precedence designators. 213.5 Section 213.5 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.5 Precedence designators. (a) The following precedence...

  1. 47 CFR 213.5 - Precedence designators.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Precedence designators. 213.5 Section 213.5 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL GOVERNMENT AND PUBLIC CORRESPONDENCE TELECOMMUNICATIONS PRECEDENCE SYSTEM § 213.5 Precedence designators. (a) The following precedence...

  2. 49 CFR 213.63 - Track surface.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Track surface. 213.63 Section 213.63 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION TRACK SAFETY STANDARDS Track Geometry § 213.63 Track surface. Each owner of the...

  3. 49 CFR 213.63 - Track surface.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Track surface. 213.63 Section 213.63 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION TRACK SAFETY STANDARDS Track Geometry § 213.63 Track surface. Each owner of the...

  4. 47 CFR 13.213 - COLEM qualifications.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false COLEM qualifications. 13.213 Section 13.213 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL RADIO OPERATORS Examination System § 13.213... more types of commercial radio operator licenses and/or endorsements; (d) Agree to assure that, for any...

  5. 49 CFR 213.19 - Information collection.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Information collection. 213.19 Section 213.19..., DEPARTMENT OF TRANSPORTATION TRACK SAFETY STANDARDS General § 213.19 Information collection. (a) The information collection requirements of this part were reviewed by the Office of Management and Budget pursuant...

  6. Alpha Particles Induce Autophagy in Multiple Myeloma Cells.

    PubMed

    Gorin, Jean-Baptiste; Gouard, Sébastien; Ménager, Jérémie; Morgenstern, Alfred; Bruchertseifer, Frank; Faivre-Chauvet, Alain; Guilloux, Yannick; Chérel, Michel; Davodeau, François; Gaschet, Joëlle

    2015-01-01

    Radiation emitted by the radionuclides in radioimmunotherapy (RIT) approaches induce direct killing of the targeted cells as well as indirect killing through the bystander effect. Our research group is dedicated to the development of α-RIT, i.e., RIT using α-particles especially for the treatment of multiple myeloma (MM). γ-irradiation and β-irradiation have been shown to trigger apoptosis in tumor cells. Cell death mode induced by (213)Bi α-irradiation appears more controversial. We therefore decided to investigate the effects of (213)Bi on MM cell radiobiology, notably cell death mechanisms as well as tumor cell immunogenicity after irradiation. Murine 5T33 and human LP-1 MM cell lines were used to study the effects of such α-particles. We first examined the effects of (213)Bi on proliferation rate, double-strand DNA breaks, cell cycle, and cell death. Then, we investigated autophagy after (213)Bi irradiation. Finally, a coculture of dendritic cells (DCs) with irradiated tumor cells or their culture media was performed to test whether it would induce DC activation. We showed that (213)Bi induces DNA double-strand breaks, cell cycle arrest, and autophagy in both cell lines, but we detected only slight levels of early apoptosis within the 120 h following irradiation in 5T33 and LP-1. Inhibition of autophagy prevented (213)Bi-induced inhibition of proliferation in LP-1 suggesting that this mechanism is involved in cell death after irradiation. We then assessed the immunogenicity of irradiated cells and found that irradiated LP-1 can activate DC through the secretion of soluble factor(s); however, no increase in membrane or extracellular expression of danger-associated molecular patterns was observed after irradiation. This study demonstrates that (213)Bi induces mainly necrosis in MM cells, low levels of apoptosis, and autophagy that might be involved in tumor cell death.

  7. Induction of micronuclei and apoptosis in natural killer cells compared to T lymphocytes after gamma-irradiation.

    PubMed

    Louagie, H; Philippé, J; Vral, A; Cornelissen, M; Thierens, H; De Ridder, L

    1998-02-01

    To investigate the chromosomal damage caused by gamma-irradiation in T lymphocytes and natural killer (NK) cells and compare this with apoptosis induction in both lymphocyte subsets. Apoptosis induction by gamma-irradiation in T lymphocytes and NK cells was quantified using the annexin V flow cytometric assay. The cytokinesis-block micronucleus (MN) assay was used to evaluate the induced cytogenetic damage. For the MN assays on NK cells, gamma-irradiated peripheral blood mononuclear cells were cultured and stimulated with interleukin 15 (IL-15). Afterwards the NK cells (characterized by the CD3-/CD56+ phenotype) were separated with the FACSort flow cytometer and the number of MN in the sorted binuclear cells was scored. Doses of 1 and 2 Gy gamma-irradiation were applied. Higher numbers of MN in NK cells were found compared with the MN yield in T lymphocytes. In contrast, NK cells were less than T lymphocytes prone to apoptosis after gamma-irradiation. The results support the view that cytogenetic damage and apoptosis after gamma-irradiation are not necessarily correlated.

  8. Depression of T lymphocyte function in chimpanzees receiving thymectomy and irradiation. [X Radiation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gilbertsen, R.B.; Metzgar, R.S.

    1978-03-01

    In studies analogous to those in which the thymus dependency of immune functions in murine systems was determined, three chimpanzees were thymectomized, splenectomized, exposed to lethal doses of whole body x-irradiation with limited bone marrow shielding, and subsequently evaluated for lymphocyte markers and functions over a period of years. In the oldest animal studied (Irena, 7.2 years at surgery), the percentage of peripheral blood T cells decreased to about 60% of control values and remained at that level for approximately 1/sup 1///sub 2/ years before returning to normal. In the two youngest chimpanzees T cell rosette values dropped to 15more » to 40% of control values after irradiation. T cell percentages in one of these young chimpanzees returned to about 75% of the controls 2/sup 1///sub 2/ years after x-irradiation. Phytohemagglutinin and concanavalin A mitogen responses were less affected in the oldest chimpanzee. However, even in the oldest animal, the responses to phytohemagglutinin and concanavalin A began to show a gradual and consistent decline 1/sup 1///sub 2/ years after irradiation. Mixed leukocyte culture responsiveness was most affected by the experimental procedures, being greatly reduced in all three chimpanzees during varying time intervals. In general, the effects of the experimental procedures used to produce T cell deficiencies varied with the age of the chimpanzee at surgery, the time after irradiation when the animal was tested, and the lymphocyte marker or function studied.« less

  9. 29 CFR 780.213 - Produce business.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 3 2012-07-01 2012-07-01 false Produce business. 780.213 Section 780.213 Labor Regulations... Specific Situations Hatchery Operations § 780.213 Produce business. In some instances, hatcheries also engage in the produce business as such and commingle with the culled eggs and chickens other eggs and...

  10. 29 CFR 780.213 - Produce business.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 3 2014-07-01 2014-07-01 false Produce business. 780.213 Section 780.213 Labor Regulations... Specific Situations Hatchery Operations § 780.213 Produce business. In some instances, hatcheries also engage in the produce business as such and commingle with the culled eggs and chickens other eggs and...

  11. 29 CFR 780.213 - Produce business.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 3 2013-07-01 2013-07-01 false Produce business. 780.213 Section 780.213 Labor Regulations... Specific Situations Hatchery Operations § 780.213 Produce business. In some instances, hatcheries also engage in the produce business as such and commingle with the culled eggs and chickens other eggs and...

  12. 29 CFR 780.213 - Produce business.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false Produce business. 780.213 Section 780.213 Labor Regulations... Specific Situations Hatchery Operations § 780.213 Produce business. In some instances, hatcheries also engage in the produce business as such and commingle with the culled eggs and chickens other eggs and...

  13. 29 CFR 780.213 - Produce business.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Produce business. 780.213 Section 780.213 Labor Regulations... Specific Situations Hatchery Operations § 780.213 Produce business. In some instances, hatcheries also engage in the produce business as such and commingle with the culled eggs and chickens other eggs and...

  14. 22 CFR 213.4 - Other remedies.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Other remedies. 213.4 Section 213.4 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT CLAIMS COLLECTION General § 213.4 Other remedies. (a) This... remedies and sanctions available to the Agency under this part for collecting debts are not intended to be...

  15. 22 CFR 213.4 - Other remedies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Other remedies. 213.4 Section 213.4 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT CLAIMS COLLECTION General § 213.4 Other remedies. (a) This... remedies and sanctions available to the Agency under this part for collecting debts are not intended to be...

  16. 22 CFR 213.9 - Written notice.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Written notice. 213.9 Section 213.9 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT CLAIMS COLLECTION Collection § 213.9 Written notice. (a) When the billing official determines that a debt is owed USAID, he or she provides a written notice in the...

  17. Induction of lambda prophage by 213 nm laser radiation: a quantitative comparison with 193 nm excimer radiation using image analysis.

    PubMed

    Matchette, L S; Grossman, L W; Hahn, D W; Cooney, C

    1996-03-01

    We compared the DNA damage produced by radiation from two UV laser wavelengths, 213 nm and 193 nm, with that produced by noncoherent 254 nm radiation. Following irradiation of Escherichia coli BR339, a bacteriophage lambda lysogen containing the lacZ gene, pro-phage induction was measured by assaying for beta-galactosidase. Because of the limited penetration by UV laser wavelengths an agar overlay of the lysogen was used as the irradiation target. Irradiation of 254 nm was performed in buffer suspension followed by transfer of 5 microL spots onto assay plants. Computer image analysis was used to monitor the rate of product formation, observed as an increase in optical density of the irradiated zones on assay plates. We found that the rate of product formation was a more reproducible unit of comparison than the optical density present at the end of the reaction. Although the rate of product formation was not linearly related to enzyme concentration, the data could be fit to a simple logarithmic function. Using this method, we concluded that the DNA damaging ability of 213 nm radiation was 10 times more efficient than 193 nm radiation and about 100 times less efficient than 254 nm noncoherent radiation.

  18. 7 CFR 1951.213 - Debt settlement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 14 2010-01-01 2009-01-01 true Debt settlement. 1951.213 Section 1951.213 Agriculture... and Grants § 1951.213 Debt settlement. Subpart C of part 1956 of this chapter prescribes policies and procedures for debt settlement actions for loans covered under this subpart when it is determined that a debt...

  19. 25 CFR 213.10 - Lessor's signature.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Lessor's signature. 213.10 Section 213.10 Indians BUREAU... MEMBERS OF FIVE CIVILIZED TRIBES, OKLAHOMA, FOR MINING How to Acquire Leases § 213.10 Lessor's signature... thumbprint which shall be designated as “right” or “left” thumbmark. Such signatures must be witnessed by two...

  20. 25 CFR 213.11 - Minor lessors.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Minor lessors. 213.11 Section 213.11 Indians BUREAU OF... FIVE CIVILIZED TRIBES, OKLAHOMA, FOR MINING How to Acquire Leases § 213.11 Minor lessors. Where the lessor is a minor, certified copies of letters of guardianship and court orders approving leases must be...

  1. 25 CFR 213.11 - Minor lessors.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Minor lessors. 213.11 Section 213.11 Indians BUREAU OF... FIVE CIVILIZED TRIBES, OKLAHOMA, FOR MINING How to Acquire Leases § 213.11 Minor lessors. Where the lessor is a minor, certified copies of letters of guardianship and court orders approving leases must be...

  2. 45 CFR 213.23a - Discovery.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 2 2014-10-01 2012-10-01 true Discovery. 213.23a Section 213.23a Public Welfare... Discovery. The Department and any party named in the notice issued pursuant to § 213.11 shall have the right to conduct discovery (including depositions) against opposing parties. Rules 26-37 of the Federal...

  3. 45 CFR 213.23a - Discovery.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 2 2012-10-01 2012-10-01 false Discovery. 213.23a Section 213.23a Public Welfare... Discovery. The Department and any party named in the notice issued pursuant to § 213.11 shall have the right to conduct discovery (including depositions) against opposing parties. Rules 26-37 of the Federal...

  4. 45 CFR 213.23a - Discovery.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 2 2011-10-01 2011-10-01 false Discovery. 213.23a Section 213.23a Public Welfare... Discovery. The Department and any party named in the notice issued pursuant to § 213.11 shall have the right to conduct discovery (including depositions) against opposing parties. Rules 26-37 of the Federal...

  5. 45 CFR 213.23a - Discovery.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true Discovery. 213.23a Section 213.23a Public Welfare... Discovery. The Department and any party named in the notice issued pursuant to § 213.11 shall have the right to conduct discovery (including depositions) against opposing parties. Rules 26-37 of the Federal...

  6. 45 CFR 213.23a - Discovery.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Discovery. 213.23a Section 213.23a Public Welfare... Discovery. The Department and any party named in the notice issued pursuant to § 213.11 shall have the right to conduct discovery (including depositions) against opposing parties. Rules 26-37 of the Federal...

  7. Collaborative Working Architecture for IoT-Based Applications.

    PubMed

    Mora, Higinio; Signes-Pont, María Teresa; Gil, David; Johnsson, Magnus

    2018-05-23

    The new sensing applications need enhanced computing capabilities to handle the requirements of complex and huge data processing. The Internet of Things (IoT) concept brings processing and communication features to devices. In addition, the Cloud Computing paradigm provides resources and infrastructures for performing the computations and outsourcing the work from the IoT devices. This scenario opens new opportunities for designing advanced IoT-based applications, however, there is still much research to be done to properly gear all the systems for working together. This work proposes a collaborative model and an architecture to take advantage of the available computing resources. The resulting architecture involves a novel network design with different levels which combines sensing and processing capabilities based on the Mobile Cloud Computing (MCC) paradigm. An experiment is included to demonstrate that this approach can be used in diverse real applications. The results show the flexibility of the architecture to perform complex computational tasks of advanced applications.

  8. 42 CFR 456.213 - Confidentiality.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Confidentiality. 456.213 Section 456.213 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Utilization Control: Mental Hospitals Ur Plan...

  9. 49 CFR 213.3 - Application.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... an urban area that are not connected with the general railroad system of transportation. ... 49 Transportation 4 2010-10-01 2010-10-01 false Application. 213.3 Section 213.3 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF...

  10. 49 CFR 37.213 - Information collection requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Information collection requirements. 37.213 Section 37.213 Transportation Office of the Secretary of Transportation TRANSPORTATION SERVICES FOR INDIVIDUALS WITH DISABILITIES (ADA) Over-the-Road Buses (OTRBs) § 37.213 Information collection requirements...

  11. 28 CFR 115.213 - Supervision and monitoring.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Supervision and monitoring. 115.213 Section 115.213 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Prevention Planning § 115.213 Supervision...

  12. 28 CFR 115.213 - Supervision and monitoring.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Supervision and monitoring. 115.213 Section 115.213 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Prevention Planning § 115.213 Supervision...

  13. 28 CFR 115.213 - Supervision and monitoring.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Supervision and monitoring. 115.213 Section 115.213 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Prevention Planning § 115.213 Supervision...

  14. 49 CFR 219.213 - Unlawful refusals; consequences.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Unlawful refusals; consequences. 219.213 Section 219.213 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... § 219.213 Unlawful refusals; consequences. (a) Disqualification. An employee who refuses to cooperate in...

  15. 28 CFR 2.13 - Initial hearing; procedure.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Initial hearing; procedure. 2.13 Section 2.13 Judicial Administration DEPARTMENT OF JUSTICE PAROLE, RELEASE, SUPERVISION AND RECOMMITMENT OF PRISONERS, YOUTH OFFENDERS, AND JUVENILE DELINQUENTS United States Code Prisoners and Parolees § 2.13...

  16. 28 CFR 2.13 - Initial hearing; procedure.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Initial hearing; procedure. 2.13 Section 2.13 Judicial Administration DEPARTMENT OF JUSTICE PAROLE, RELEASE, SUPERVISION AND RECOMMITMENT OF PRISONERS, YOUTH OFFENDERS, AND JUVENILE DELINQUENTS United States Code Prisoners and Parolees § 2.13...

  17. 29 CFR 2.13 - Audiovisual coverage prohibited.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Audiovisual coverage prohibited. 2.13 Section 2.13 Labor Office of the Secretary of Labor GENERAL REGULATIONS Audiovisual Coverage of Administrative Hearings § 2.13 Audiovisual coverage prohibited. The Department shall not permit audiovisual coverage of the...

  18. 49 CFR 213.345 - Vehicle qualification testing.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Vehicle qualification testing. 213.345 Section 213... Higher § 213.345 Vehicle qualification testing. (a) All rolling stock types which operate at Class 6... demonstrate that the vehicle dynamic response to track alinement and geometry variations are within acceptable...

  19. 32 CFR 724.213 - Attendance of witnesses.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... BOARD Authority/Policy for Departmental Discharge Review § 724.213 Attendance of witnesses. Arrangement for attendance of witnesses testifying in behalf of the applicant at discharge review hearings is the... 32 National Defense 5 2010-07-01 2010-07-01 false Attendance of witnesses. 724.213 Section 724.213...

  20. 45 CFR 213.27 - Unsponsored written material.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Unsponsored written material. 213.27 Section 213... Procedures § 213.27 Unsponsored written material. Letters expressing views or urging action and other unsponsored written material regarding matters in issue in a hearing will be placed in the correspondence...

  1. 42 CFR 1002.213 - Appeals of exclusions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Appeals of exclusions. 1002.213 Section 1002.213... AUTHORITIES PROGRAM INTEGRITY-STATE-INITIATED EXCLUSIONS FROM MEDICAID Permissive Exclusions § 1002.213 Appeals of exclusions. Before imposing an exclusion under § 1002.210, the State agency must give the...

  2. 47 CFR 15.213 - Cable locating equipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Cable locating equipment. 15.213 Section 15.213 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL RADIO FREQUENCY DEVICES Intentional Radiators § 15.213 Cable locating equipment. An intentional radiator used as cable locating equipment, as defined in § 15.3...

  3. 20 CFR 703.213 - Failure to comply.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Failure to comply. 703.213 Section 703.213 Employees' Benefits EMPLOYMENT STANDARDS ADMINISTRATION, DEPARTMENT OF LABOR LONGSHOREMEN'S AND HARBOR... Requirements § 703.213 Failure to comply. The Office may suspend or revoke a carrier's certificate of authority...

  4. Microstructure evolution of T91 irradiated in the BOR60 fast reactor

    NASA Astrophysics Data System (ADS)

    Jiao, Z.; Taller, S.; Field, K.; Yeli, G.; Moody, M. P.; Was, G. S.

    2018-06-01

    Microstructures of T91 neutron irradiated in the BOR60 reactor at five temperatures between 376 °C and 524 °C to doses between 15.4 and 35.1 dpa were characterized using transmission electron microscopy (TEM), scanning transmission electron microscopy (STEM), and atom probe tomography (APT). Type a<100> dislocation loops were observed at 376-415 °C and network dislocations dominated at 460 °C and 524 °C. Cavities appeared in a bimodal distribution with a high density of small bubbles less than 2 nm at irradiation temperatures between 376 °C and 415 °C. Small bubbles were also observed at 460 °C and 524 °C but cavities greater than 2 nm were absent. Enrichment of Cr, Ni, and Si at the grain boundary was observed at all irradiation temperatures. Radiation-induced segregation (RIS) of Cr, Ni and Si appeared to saturate at 17.1 dpa and 376 °C. The temperature dependence of RIS of Cr, Ni and Si at the grain boundary, which showed a peak Cr enrichment temperature of 460 °C and a lower peak Ni and Si enrichment temperature of ∼400 °C, was consistent with observations of RIS of Cr in proton irradiated T91, suggesting that the same RIS mechanism may also apply to BOR60 irradiated T91. G-phase and Cu-rich precipitates were observed at 376-415 °C but were absent at 460 °C and 524 °C. The absence of G-phase at 524 °C could be related to the minimal segregation of Ni and Si in that condition.

  5. 32 CFR 213.3 - Definition.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 2 2014-07-01 2014-07-01 false Definition. 213.3 Section 213.3 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS SUPPORT FOR... entities. A non-Federal entity is generally a self-sustaining, non-Federal person or organization...

  6. 32 CFR 213.3 - Definition.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 2 2013-07-01 2013-07-01 false Definition. 213.3 Section 213.3 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS SUPPORT FOR... entities. A non-Federal entity is generally a self-sustaining, non-Federal person or organization...

  7. 32 CFR 213.3 - Definition.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false Definition. 213.3 Section 213.3 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS SUPPORT FOR... entities. A non-Federal entity is generally a self-sustaining, non-Federal person or organization...

  8. 32 CFR 213.3 - Definition.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 2 2012-07-01 2012-07-01 false Definition. 213.3 Section 213.3 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS SUPPORT FOR... entities. A non-Federal entity is generally a self-sustaining, non-Federal person or organization...

  9. 32 CFR 213.3 - Definition.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Definition. 213.3 Section 213.3 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS SUPPORT FOR... entities. A non-Federal entity is generally a self-sustaining, non-Federal person or organization...

  10. 6 CFR 21.3 - Application.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 6 Domestic Security 1 2012-01-01 2012-01-01 false Application. 21.3 Section 21.3 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY NONDISCRIMINATION ON THE BASIS OF RACE, COLOR, OR NATIONAL ORIGIN IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM THE DEPARTMENT OF...

  11. 6 CFR 21.3 - Application.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Application. 21.3 Section 21.3 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY NONDISCRIMINATION ON THE BASIS OF RACE, COLOR, OR NATIONAL ORIGIN IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM THE DEPARTMENT OF...

  12. 6 CFR 21.3 - Application.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 6 Domestic Security 1 2013-01-01 2013-01-01 false Application. 21.3 Section 21.3 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY NONDISCRIMINATION ON THE BASIS OF RACE, COLOR, OR NATIONAL ORIGIN IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM THE DEPARTMENT OF...

  13. 6 CFR 21.3 - Application.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 6 Domestic Security 1 2014-01-01 2014-01-01 false Application. 21.3 Section 21.3 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY NONDISCRIMINATION ON THE BASIS OF RACE, COLOR, OR NATIONAL ORIGIN IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM THE DEPARTMENT OF...

  14. 6 CFR 21.3 - Application.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 6 Domestic Security 1 2011-01-01 2011-01-01 false Application. 21.3 Section 21.3 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY NONDISCRIMINATION ON THE BASIS OF RACE, COLOR, OR NATIONAL ORIGIN IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM THE DEPARTMENT OF...

  15. 20 CFR 703.213 - Failure to comply.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 4 2013-04-01 2013-04-01 false Failure to comply. 703.213 Section 703.213 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR LONGSHOREMEN'S AND HARBOR... Requirements § 703.213 Failure to comply. The Office may suspend or revoke a carrier's certificate of authority...

  16. 20 CFR 703.213 - Failure to comply.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false Failure to comply. 703.213 Section 703.213 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR LONGSHOREMEN'S AND HARBOR... Requirements § 703.213 Failure to comply. The Office may suspend or revoke a carrier's certificate of authority...

  17. 20 CFR 703.213 - Failure to comply.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 4 2012-04-01 2012-04-01 false Failure to comply. 703.213 Section 703.213 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR LONGSHOREMEN'S AND HARBOR... Requirements § 703.213 Failure to comply. The Office may suspend or revoke a carrier's certificate of authority...

  18. 7 CFR 1280.213 - Investment of funds.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Investment of funds. 1280.213 Section 1280.213... INFORMATION ORDER Lamb Promotion, Research, and Information Order Expenses § 1280.213 Investment of funds. The... the United States. Income from any such investment may be used for any purpose for which the invested...

  19. 7 CFR 1280.213 - Investment of funds.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Investment of funds. 1280.213 Section 1280.213... INFORMATION ORDER Lamb Promotion, Research, and Information Order Expenses § 1280.213 Investment of funds. The... the United States. Income from any such investment may be used for any purpose for which the invested...

  20. 10 CFR 1015.213 - Analysis of costs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... and in various dollar ranges will be used to compare the cost effectiveness of alternative collection... 10 Energy 4 2010-01-01 2010-01-01 false Analysis of costs. 1015.213 Section 1015.213 Energy... Administrative Collection of Claims § 1015.213 Analysis of costs. DOE will prepare periodic comparisons of costs...

  1. 49 CFR 232.213 - Extended haul trains.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Extended haul trains. 232.213 Section 232.213... EQUIPMENT; END-OF-TRAIN DEVICES Inspection and Testing Requirements § 232.213 Extended haul trains. (a) A... inspections if the railroad designates a train as an extended haul train. In order for a railroad to designate...

  2. 49 CFR 232.213 - Extended haul trains.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Extended haul trains. 232.213 Section 232.213... EQUIPMENT; END-OF-TRAIN DEVICES Inspection and Testing Requirements § 232.213 Extended haul trains. (a) A... inspections if the railroad designates a train as an extended haul train. In order for a railroad to designate...

  3. 49 CFR 232.213 - Extended haul trains.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Extended haul trains. 232.213 Section 232.213... EQUIPMENT; END-OF-TRAIN DEVICES Inspection and Testing Requirements § 232.213 Extended haul trains. (a) A... inspections if the railroad designates a train as an extended haul train. In order for a railroad to designate...

  4. 49 CFR 232.213 - Extended haul trains.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Extended haul trains. 232.213 Section 232.213... EQUIPMENT; END-OF-TRAIN DEVICES Inspection and Testing Requirements § 232.213 Extended haul trains. (a) A... inspections if the railroad designates a train as an extended haul train. In order for a railroad to designate...

  5. 21 CFR 21.3 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Definitions. 21.3 Section 21.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROTECTION OF PRIVACY General... products regulated by the Food and Drug Administration or with which the Food and Drug Administration has...

  6. 21 CFR 21.3 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Definitions. 21.3 Section 21.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROTECTION OF PRIVACY General... products regulated by the Food and Drug Administration or with which the Food and Drug Administration has...

  7. 21 CFR 21.3 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Definitions. 21.3 Section 21.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROTECTION OF PRIVACY General... products regulated by the Food and Drug Administration or with which the Food and Drug Administration has...

  8. 21 CFR 21.3 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Definitions. 21.3 Section 21.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROTECTION OF PRIVACY General... products regulated by the Food and Drug Administration or with which the Food and Drug Administration has...

  9. 49 CFR 213.122 - Torch cut rail.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Torch cut rail. 213.122 Section 213.122..., DEPARTMENT OF TRANSPORTATION TRACK SAFETY STANDARDS Track Structure § 213.122 Torch cut rail. (a) Except as a temporary repair in emergency situations no rail having a torch cut end shall be used in Classes 3 through 5...

  10. 45 CFR 213.14 - Issues at hearing.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Issues at hearing. 213.14 Section 213.14 Public...-Notice and Parties § 213.14 Issues at hearing. (a) The Administrator may, prior to a hearing under § 201.6 (a) or (b) of this chapter, notify the State in writing of additional issues which will be...

  11. 49 CFR 213.122 - Torch cut rail.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Torch cut rail. 213.122 Section 213.122..., DEPARTMENT OF TRANSPORTATION TRACK SAFETY STANDARDS Track Structure § 213.122 Torch cut rail. (a) Except as a temporary repair in emergency situations no rail having a torch cut end shall be used in Classes 3 through 5...

  12. 49 CFR 213.139 - Spring rail frogs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Spring rail frogs. 213.139 Section 213.139..., DEPARTMENT OF TRANSPORTATION TRACK SAFETY STANDARDS Track Structure § 213.139 Spring rail frogs. (a) The outer edge of a wheel tread shall not contact the gage side of a spring wing rail. (b) The toe of each...

  13. 49 CFR 213.139 - Spring rail frogs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Spring rail frogs. 213.139 Section 213.139..., DEPARTMENT OF TRANSPORTATION TRACK SAFETY STANDARDS Track Structure § 213.139 Spring rail frogs. (a) The outer edge of a wheel tread shall not contact the gage side of a spring wing rail. (b) The toe of each...

  14. 49 CFR 213.139 - Spring rail frogs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Spring rail frogs. 213.139 Section 213.139..., DEPARTMENT OF TRANSPORTATION TRACK SAFETY STANDARDS Track Structure § 213.139 Spring rail frogs. (a) The outer edge of a wheel tread shall not contact the gage side of a spring wing rail. (b) The toe of each...

  15. 49 CFR 213.139 - Spring rail frogs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Spring rail frogs. 213.139 Section 213.139..., DEPARTMENT OF TRANSPORTATION TRACK SAFETY STANDARDS Track Structure § 213.139 Spring rail frogs. (a) The outer edge of a wheel tread shall not contact the gage side of a spring wing rail. (b) The toe of each...

  16. 49 CFR 213.139 - Spring rail frogs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Spring rail frogs. 213.139 Section 213.139..., DEPARTMENT OF TRANSPORTATION TRACK SAFETY STANDARDS Track Structure § 213.139 Spring rail frogs. (a) The outer edge of a wheel tread shall not contact the gage side of a spring wing rail. (b) The toe of each...

  17. Microstructure evolution of T91 irradiated in the BOR60 fast reactor

    DOE PAGES

    Jiao, Z.; Taller, S.; Field, K.; ...

    2018-03-14

    In this paper, microstructures of T91 neutron irradiated in the BOR60 reactor at five temperatures between 376 °C and 524 °C to doses between 15.4 and 35.1 dpa were characterized using transmission electron microscopy (TEM), scanning transmission electron microscopy (STEM), and atom probe tomography (APT). Type a<100> dislocation loops were observed at 376–415 °C and network dislocations dominated at 460 °C and 524 °C. Cavities appeared in a bimodal distribution with a high density of small bubbles less than 2 nm at irradiation temperatures between 376 °C and 415 °C. Small bubbles were also observed at 460 °C and 524more » °C but cavities greater than 2 nm were absent. Enrichment of Cr, Ni, and Si at the grain boundary was observed at all irradiation temperatures. Radiation-induced segregation (RIS) of Cr, Ni and Si appeared to saturate at 17.1 dpa and 376 °C. The temperature dependence of RIS of Cr, Ni and Si at the grain boundary, which showed a peak Cr enrichment temperature of 460 °C and a lower peak Ni and Si enrichment temperature of ~400 °C, was consistent with observations of RIS of Cr in proton irradiated T91, suggesting that the same RIS mechanism may also apply to BOR60 irradiated T91. G-phase and Cu-rich precipitates were observed at 376–415 °C but were absent at 460 °C and 524 °C. Finally, the absence of G-phase at 524 °C could be related to the minimal segregation of Ni and Si in that condition.« less

  18. Microstructure evolution of T91 irradiated in the BOR60 fast reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jiao, Z.; Taller, S.; Field, K.

    In this paper, microstructures of T91 neutron irradiated in the BOR60 reactor at five temperatures between 376 °C and 524 °C to doses between 15.4 and 35.1 dpa were characterized using transmission electron microscopy (TEM), scanning transmission electron microscopy (STEM), and atom probe tomography (APT). Type a<100> dislocation loops were observed at 376–415 °C and network dislocations dominated at 460 °C and 524 °C. Cavities appeared in a bimodal distribution with a high density of small bubbles less than 2 nm at irradiation temperatures between 376 °C and 415 °C. Small bubbles were also observed at 460 °C and 524more » °C but cavities greater than 2 nm were absent. Enrichment of Cr, Ni, and Si at the grain boundary was observed at all irradiation temperatures. Radiation-induced segregation (RIS) of Cr, Ni and Si appeared to saturate at 17.1 dpa and 376 °C. The temperature dependence of RIS of Cr, Ni and Si at the grain boundary, which showed a peak Cr enrichment temperature of 460 °C and a lower peak Ni and Si enrichment temperature of ~400 °C, was consistent with observations of RIS of Cr in proton irradiated T91, suggesting that the same RIS mechanism may also apply to BOR60 irradiated T91. G-phase and Cu-rich precipitates were observed at 376–415 °C but were absent at 460 °C and 524 °C. Finally, the absence of G-phase at 524 °C could be related to the minimal segregation of Ni and Si in that condition.« less

  19. 49 CFR 213.137 - Frogs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... than 10 m.p.h. (c) If the tread portion of a frog casting is worn down more than three-eighths inch below the original contour, operating speed over that frog shall not be more than 10 m.p.h. (d) Where... 49 Transportation 4 2011-10-01 2011-10-01 false Frogs. 213.137 Section 213.137 Transportation...

  20. 48 CFR 213.303 - Blanket purchase agreements (BPAs).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Blanket purchase agreements (BPAs). 213.303 Section 213.303 Federal Acquisition Regulations System DEFENSE ACQUISITION... PROCEDURES Simplified Acquisition Methods 213.303 Blanket purchase agreements (BPAs). ...

  1. Ion-irradiation-induced microstructural modifications in ferritic/martensitic steel T91

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, Xiang; Miao, Yinbin; Li, Meimei

    In this paper, in situ transmission electron microscopy investigations were carried out to study the microstructural evolution of ferritic/martensitic steel T91 under 1 MeV Krypton ion irradiation up to 4.2 x 10(15) ions/cm(2) at 573 K, 673 K, and 773 K. At 573 K, grown-in defects are strongly modified by black dot loops, and dislocation networks together with black-dot loops were observed after irradiation. At 673 K and 773 K, grown-in defects are only partially modified by dislocation loops; isolated loops and dislocation segments were commonly found after irradiation. Post irradiation examination indicates that at 4.2 x 1015 ions/cm(2), aboutmore » 51% of the loops were a(0)/2 < 111 > type for the 673 K irradiation, and the dominant loop type was a(0)< 100 > for the 773 K irradiation. Finally, a dispersed barrier hardening model was employed to estimate the change in yield strength, and the calculated ion data were found to follow the similar trend as the existing neutron data with an offset of 100-150 MPa. (C) 2017 Elsevier B.V. All rights reserved.« less

  2. 47 CFR 36.213 - Network access services revenues.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Network access services revenues. 36.213 Section 36.213 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES... Income Accounts Operating Revenues § 36.213 Network access services revenues. (a) End User Revenue...

  3. 47 CFR 36.213 - Network access services revenues.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 2 2011-10-01 2011-10-01 false Network access services revenues. 36.213 Section 36.213 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES... Income Accounts Operating Revenues § 36.213 Network access services revenues. (a) End User Revenue...

  4. 7 CFR 920.213 - Assessment rate.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Assessment rate. 920.213 Section 920.213 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE KIWIFRUIT GROWN IN CALIFORNIA...

  5. 7 CFR 920.213 - Assessment rate.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Assessment rate. 920.213 Section 920.213 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE KIWIFRUIT GROWN IN CALIFORNIA...

  6. 7 CFR 920.213 - Assessment rate.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Assessment rate. 920.213 Section 920.213 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE KIWIFRUIT GROWN IN CALIFORNIA...

  7. 7 CFR 920.213 - Assessment rate.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Assessment rate. 920.213 Section 920.213 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE KIWIFRUIT GROWN IN CALIFORNIA...

  8. 33 CFR 136.213 - Authorized claimants.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Authorized claimants. 136.213 Section 136.213 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

  9. 33 CFR 136.213 - Authorized claimants.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Authorized claimants. 136.213 Section 136.213 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

  10. 33 CFR 136.213 - Authorized claimants.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Authorized claimants. 136.213 Section 136.213 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

  11. 33 CFR 136.213 - Authorized claimants.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Authorized claimants. 136.213 Section 136.213 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

  12. 33 CFR 136.213 - Authorized claimants.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Authorized claimants. 136.213 Section 136.213 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

  13. 7 CFR 920.213 - Assessment rate.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Assessment rate. 920.213 Section 920.213 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE KIWIFRUIT GROWN IN CALIFORNIA...

  14. Science and Technology (S and T) Roadmap Collaboration between SMC, NASA, and Government Partners

    NASA Technical Reports Server (NTRS)

    Betser, Joseph; Ewart, Roberta; Chandler, Faith

    2016-01-01

    National Security Space (NSS) presents multi-faceted S and T challenges. We must continually innovate enterprise and information management; provide decision support; develop advanced materials; enhance sensor technology; transform communication technology; develop advanced propulsion and resilient space architectures and capabilities; and enhance multiple additional S and T domains. These challenges are best met by leveraging advanced S and T research and technology development from a number of DoD agencies and civil agencies such as NASA. The authors of this paper have engaged in these activities since 2006 and over the past decade developed multiple strategic S and T relationships. This paper highlights the Office of the Space Missile Systems Center (SMC) Chief Scientist (SMC/ST) collaboration with the NASA Office of Chief Technologist (NASA OCT), which has multiple S and T activities that are relevant to NSS. In particular we discuss the development of the Technology Roadmaps that benefit both Civil Space and NSS. Our collaboration with NASA OCT has been of mutual benefit to multiple participants. Some of the other DoD components include the Defense Advanced Research Projects agency (DARPA), Air Force Research Laboratory (AFRL), Naval Research Laboratory (NRL), The USAF Office of Chief Scientist, the USAF Science Advisory Board (SAB), Space and Naval Warfare Systems Command (SPAWAR), and a number of other services and agencies. In addition, the human talent is a key enabler of advanced S and T activities; it is absolutely critical to have a strong supply of talent in the fields of Science Technology, Engineering, and Mathematics (STEM). Consequently, we continually collaborate with the USAF Institute of Technology (AFIT), other service academies and graduate schools, and other universities and colleges. This paper highlights the benefits that result from such strategic S and T partnerships and recommends a way forward that will continually build upon these

  15. 46 CFR 109.213 - Emergency training and drills.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Emergency training and drills. 109.213 Section 109.213 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS OPERATIONS Tests, Drills, and Inspections § 109.213 Emergency training and drills. (a) Training materials...

  16. 46 CFR 109.213 - Emergency training and drills.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Emergency training and drills. 109.213 Section 109.213 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS OPERATIONS Tests, Drills, and Inspections § 109.213 Emergency training and drills. (a) Training materials...

  17. 46 CFR 109.213 - Emergency training and drills.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Emergency training and drills. 109.213 Section 109.213 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS OPERATIONS Tests, Drills, and Inspections § 109.213 Emergency training and drills. (a) Training materials...

  18. 46 CFR 109.213 - Emergency training and drills.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Emergency training and drills. 109.213 Section 109.213 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS OPERATIONS Tests, Drills, and Inspections § 109.213 Emergency training and drills. (a) Training materials...

  19. 46 CFR 109.213 - Emergency training and drills.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Emergency training and drills. 109.213 Section 109.213 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS OPERATIONS Tests, Drills, and Inspections § 109.213 Emergency training and drills. (a) Training materials...

  20. 24 CFR 213.267 - Effect of insurance endorsement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Effect of insurance endorsement. 213.267 Section 213.267 Housing and Urban Development Regulations Relating to Housing and Urban... AUTHORITIES COOPERATIVE HOUSING MORTGAGE INSURANCE Contract Rights and Obligations-Projects § 213.267 Effect...

  1. 19 CFR 213.5 - Access to Commission resources.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Access to Commission resources. 213.5 Section 213.5 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.5 Access to Commission resources. Commission resources, in...

  2. 19 CFR 213.5 - Access to Commission resources.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 3 2011-04-01 2011-04-01 false Access to Commission resources. 213.5 Section 213.5 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.5 Access to Commission resources. Commission resources, in...

  3. 19 CFR 213.5 - Access to Commission resources.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 3 2013-04-01 2013-04-01 false Access to Commission resources. 213.5 Section 213.5 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.5 Access to Commission resources. Commission resources, in...

  4. 19 CFR 213.5 - Access to Commission resources.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 3 2014-04-01 2014-04-01 false Access to Commission resources. 213.5 Section 213.5 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.5 Access to Commission resources. Commission resources, in...

  5. 22 CFR 213.39 - Exceptions to mandatory transfer.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Exceptions to mandatory transfer. 213.39 Section 213.39 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT CLAIMS COLLECTION Mandatory Transfer of Delinquent Debt to Financial Management Service (FMS) of the Department of Treasury § 213.39...

  6. 29 CFR 1603.213 - Interlocutory review.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Interlocutory review. 1603.213 Section 1603.213 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES FOR PREVIOUSLY EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF...

  7. 29 CFR 1603.213 - Interlocutory review.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 4 2013-07-01 2013-07-01 false Interlocutory review. 1603.213 Section 1603.213 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES FOR PREVIOUSLY EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF...

  8. 29 CFR 1603.213 - Interlocutory review.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 4 2012-07-01 2012-07-01 false Interlocutory review. 1603.213 Section 1603.213 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES FOR PREVIOUSLY EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF...

  9. 29 CFR 1603.213 - Interlocutory review.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 4 2014-07-01 2014-07-01 false Interlocutory review. 1603.213 Section 1603.213 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES FOR PREVIOUSLY EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF...

  10. 29 CFR 1603.213 - Interlocutory review.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 4 2011-07-01 2011-07-01 false Interlocutory review. 1603.213 Section 1603.213 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES FOR PREVIOUSLY EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF...

  11. 49 CFR 213.9 - Classes of track: operating speed limits.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Classes of track: operating speed limits. 213.9... speed limits. (a) Except as provided in paragraph (b) of this section and §§ 213.57(b), 213.59(a), 213.113(a), and 213.137(b) and (c), the following maximum allowable operating speeds apply— [In miles per...

  12. 49 CFR 213.9 - Classes of track: operating speed limits.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Classes of track: operating speed limits. 213.9... speed limits. (a) Except as provided in paragraph (b) of this section and §§ 213.57(b), 213.59(a), 213.113(a), and 213.137(b) and (c), the following maximum allowable operating speeds apply— [In miles per...

  13. 48 CFR 213.303-5 - Purchases under BPAs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Purchases under BPAs. 213.303-5 Section 213.303-5 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... Acquisition Methods 213.303-5 Purchases under BPAs. (b) Individual purchases for subsistence may be made at...

  14. Fracture toughness and Charpy impact properties of several RAFMS before and after irradiation in HFIR

    NASA Astrophysics Data System (ADS)

    Sokolov, M. A.; Tanigawa, H.; Odette, G. R.; Shiba, K.; Klueh, R. L.

    2007-08-01

    As part of the development of candidate reduced-activation ferritic steels for fusion applications, several steels, namely F82H, 9Cr-2WVTa steels and F82H weld metal, are being investigated in the joint DOE-JAEA collaboration program. Within this program, three capsules containing a variety of specimen designs were irradiated at two design temperatures in the ORNL High Flux Isotope Reactor (HFIR). Two capsules, RB-11J and RB-12J, were irradiated in the HFIR removable beryllium positions with europium oxide (Eu 2O 3) thermal neutron shields in place. Specimens were irradiated up to 5 dpa. Capsule JP25 was irradiated in the HFIR target position to 20 dpa. The design temperatures were 300 °C and 500 °C. Precracked third-sized V-notch Charpy (3.3 × 3.3 × 25.4 mm) and 0.18 T DC(T) specimens were tested to determine transition and ductile shelf fracture toughness before and after irradiation. The master curve methodology was applied to evaluate the fracture toughness transition temperature, T0. Irradiation induced shifts of T0 and reductions of JQ were compared with Charpy V-notch impact properties. Fracture toughness and Charpy shifts were also compared to hardening results.

  15. 14 CFR 61.213 - Eligibility requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Eligibility requirements. 61.213 Section 61.213 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED... necessary; (3) Except as provided in paragraph (b) of this section, pass a knowledge test on the...

  16. 14 CFR 61.213 - Eligibility requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Eligibility requirements. 61.213 Section 61.213 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED... necessary; (3) Except as provided in paragraph (b) of this section, pass a knowledge test on the...

  17. 49 CFR 213.343 - Continuous welded rail (CWR).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION TRACK SAFETY STANDARDS Train Operations at Track Classes 6 and Higher § 213.343 Continuous welded rail (CWR). Each track owner with track constructed of CWR shall have... 49 Transportation 4 2011-10-01 2011-10-01 false Continuous welded rail (CWR). 213.343 Section 213...

  18. 22 CFR 213.39 - Exceptions to mandatory transfer.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Exceptions to mandatory transfer. 213.39 Section 213.39 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT CLAIMS COLLECTION Mandatory Transfer... Exceptions to mandatory transfer. USAID is not required to transfer a debt to FMS pursuant to § 213.37(b...

  19. 22 CFR 213.39 - Exceptions to mandatory transfer.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Exceptions to mandatory transfer. 213.39 Section 213.39 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT CLAIMS COLLECTION Mandatory Transfer... Exceptions to mandatory transfer. USAID is not required to transfer a debt to FMS pursuant to § 213.37(b...

  20. 30 CFR 77.213 - Draw-off tunnel escapeways.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Draw-off tunnel escapeways. 77.213 Section 77.213 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND... Surface Installations § 77.213 Draw-off tunnel escapeways. When it is necessary for a tunnel to be closed...

  1. 50 CFR 300.213 - Vessel information.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 11 2013-10-01 2013-10-01 false Vessel information. 300.213 Section 300... REGULATIONS Western and Central Pacific Fisheries for Highly Migratory Species § 300.213 Vessel information... information about the vessel and its ownership and operation, and the authorized fishing activities, including...

  2. 12 CFR 21.3 - Security program.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 1 2014-01-01 2014-01-01 false Security program. 21.3 Section 21.3 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY MINIMUM SECURITY DEVICES AND PROCEDURES, REPORTS OF SUSPICIOUS ACTIVITIES, AND BANK SECRECY ACT COMPLIANCE PROGRAM Minimum Security Devices and...

  3. 12 CFR 21.3 - Security program.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 1 2013-01-01 2013-01-01 false Security program. 21.3 Section 21.3 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY MINIMUM SECURITY DEVICES AND PROCEDURES, REPORTS OF SUSPICIOUS ACTIVITIES, AND BANK SECRECY ACT COMPLIANCE PROGRAM Minimum Security Devices and...

  4. 12 CFR 21.3 - Security program.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 1 2011-01-01 2011-01-01 false Security program. 21.3 Section 21.3 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY MINIMUM SECURITY DEVICES AND PROCEDURES, REPORTS OF SUSPICIOUS ACTIVITIES, AND BANK SECRECY ACT COMPLIANCE PROGRAM Minimum Security Devices and...

  5. 31 CFR 800.213 - Foreign government.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Foreign government. 800.213 Section... TAKEOVERS BY FOREIGN PERSONS Definitions § 800.213 Foreign government. The term foreign government means any government or body exercising governmental functions, other than the United States Government or a...

  6. 31 CFR 800.213 - Foreign government.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Foreign government. 800.213 Section... TAKEOVERS BY FOREIGN PERSONS Definitions § 800.213 Foreign government. The term foreign government means any government or body exercising governmental functions, other than the United States Government or a...

  7. 31 CFR 800.213 - Foreign government.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Foreign government. 800.213 Section... TAKEOVERS BY FOREIGN PERSONS Definitions § 800.213 Foreign government. The term foreign government means any government or body exercising governmental functions, other than the United States Government or a...

  8. 31 CFR 800.213 - Foreign government.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Foreign government. 800.213 Section... TAKEOVERS BY FOREIGN PERSONS Definitions § 800.213 Foreign government. The term foreign government means any government or body exercising governmental functions, other than the United States Government or a...

  9. 31 CFR 800.213 - Foreign government.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Foreign government. 800.213 Section... TAKEOVERS BY FOREIGN PERSONS Definitions § 800.213 Foreign government. The term foreign government means any government or body exercising governmental functions, other than the United States Government or a...

  10. 36 CFR 21.3 - Use of thermal water.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 1 2013-07-01 2013-07-01 false Use of thermal water. 21.3 Section 21.3 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR HOT SPRINGS NATIONAL PARK; BATHHOUSE REGULATIONS § 21.3 Use of thermal water. (a) The use of the thermal...

  11. 48 CFR 213.7002 - Purchase orders.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Purchase orders. 213.7002... Acquisition Procedures Under the 8(a) Program 213.7002 Purchase orders. The contracting officer need not obtain a contractor's written acceptance of a purchase order or modification of a purchase order for an...

  12. 5 CFR 213.3199 - Temporary organizations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Temporary organizations. 213.3199 Section... SERVICE Excepted Schedules Schedule A § 213.3199 Temporary organizations. Positions on the staffs of temporary organizations, as defined in 5 U.S.C. 3161(a). Appointments may not exceed 3 years, but temporary...

  13. 12 CFR 213.9 - Relation to state laws.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 2 2011-01-01 2011-01-01 false Relation to state laws. 213.9 Section 213.9... LEASING (REGULATION M) § 213.9 Relation to state laws. (a) Inconsistent state law. A state law that is... a lessor cannot comply with a state law without violating a provision of this part, the state law is...

  14. 12 CFR 21.3 - Security program.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... banking office; (iv) The cost of the security devices; (v) Other security measures in effect at the... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Security program. 21.3 Section 21.3 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY MINIMUM SECURITY DEVICES AND PROCEDURES...

  15. 36 CFR 21.3 - Use of thermal water.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 1 2012-07-01 2012-07-01 false Use of thermal water. 21.3 Section 21.3 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR HOT SPRINGS NATIONAL PARK; BATHHOUSE REGULATIONS § 21.3 Use of thermal water. (a) The use of the thermal waters of Hot Springs National Park, for...

  16. 36 CFR 21.3 - Use of thermal water.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 1 2014-07-01 2014-07-01 false Use of thermal water. 21.3 Section 21.3 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR HOT SPRINGS NATIONAL PARK; BATHHOUSE REGULATIONS § 21.3 Use of thermal water. (a) The use of the thermal waters of Hot Springs National Park, for...

  17. 49 CFR 229.213 - Locomotive manufacturing information.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Locomotive manufacturing information. 229.213 Section 229.213 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD LOCOMOTIVE SAFETY STANDARDS Locomotive Crashworthiness...

  18. 49 CFR 229.213 - Locomotive manufacturing information.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Locomotive manufacturing information. 229.213 Section 229.213 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD LOCOMOTIVE SAFETY STANDARDS Locomotive Crashworthiness...

  19. 49 CFR 229.213 - Locomotive manufacturing information.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Locomotive manufacturing information. 229.213 Section 229.213 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD LOCOMOTIVE SAFETY STANDARDS Locomotive Crashworthiness...

  20. 49 CFR 229.213 - Locomotive manufacturing information.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Locomotive manufacturing information. 229.213 Section 229.213 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD LOCOMOTIVE SAFETY STANDARDS Locomotive Crashworthiness...

  1. 49 CFR 229.213 - Locomotive manufacturing information.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Locomotive manufacturing information. 229.213 Section 229.213 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD LOCOMOTIVE SAFETY STANDARDS Locomotive Crashworthiness...

  2. 19 CFR 213.6 - Information concerning assistance.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 213.6 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.6 Information concerning assistance. Any person may.... International Trade Commission, 500 E Street SW., Washington, DC 20436. ...

  3. 19 CFR 213.6 - Information concerning assistance.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 213.6 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.6 Information concerning assistance. Any person may.... International Trade Commission, 500 E Street SW., Washington, DC 20436. ...

  4. 19 CFR 213.6 - Information concerning assistance.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 213.6 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.6 Information concerning assistance. Any person may.... International Trade Commission, 500 E Street SW., Washington, DC 20436. ...

  5. 19 CFR 213.6 - Information concerning assistance.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 213.6 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.6 Information concerning assistance. Any person may.... International Trade Commission, 500 E Street SW., Washington, DC 20436. ...

  6. 49 CFR 213.59 - Elevation of curved track; runoff.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Elevation of curved track; runoff. 213.59 Section 213.59 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION TRACK SAFETY STANDARDS Track Geometry § 213.59 Elevation of curved...

  7. 45 CFR 213.26 - Exclusion from hearing for misconduct.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true Exclusion from hearing for misconduct. 213.26 Section 213.26 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE... REQUIREMENTS Hearing Procedures § 213.26 Exclusion from hearing for misconduct. Disrespectful, disorderly, or...

  8. 45 CFR 213.26 - Exclusion from hearing for misconduct.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 2 2012-10-01 2012-10-01 false Exclusion from hearing for misconduct. 213.26 Section 213.26 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE... REQUIREMENTS Hearing Procedures § 213.26 Exclusion from hearing for misconduct. Disrespectful, disorderly, or...

  9. 45 CFR 213.26 - Exclusion from hearing for misconduct.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 2 2014-10-01 2012-10-01 true Exclusion from hearing for misconduct. 213.26 Section 213.26 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE... REQUIREMENTS Hearing Procedures § 213.26 Exclusion from hearing for misconduct. Disrespectful, disorderly, or...

  10. 45 CFR 213.26 - Exclusion from hearing for misconduct.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 2 2011-10-01 2011-10-01 false Exclusion from hearing for misconduct. 213.26 Section 213.26 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE... REQUIREMENTS Hearing Procedures § 213.26 Exclusion from hearing for misconduct. Disrespectful, disorderly, or...

  11. 45 CFR 213.26 - Exclusion from hearing for misconduct.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Exclusion from hearing for misconduct. 213.26 Section 213.26 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE... REQUIREMENTS Hearing Procedures § 213.26 Exclusion from hearing for misconduct. Disrespectful, disorderly, or...

  12. 34 CFR 668.213 - Economically disadvantaged appeals.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Economically disadvantaged appeals. 668.213 Section 668.213 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION STUDENT ASSISTANCE GENERAL PROVISIONS Cohort Default Rates...

  13. 48 CFR 213.402 - Conditions for use.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Conditions for use. 213.402 Section 213.402 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SIMPLIFIED ACQUISITION PROCEDURES Fast Payment...

  14. 48 CFR 213.402 - Conditions for use.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Conditions for use. 213.402 Section 213.402 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SIMPLIFIED ACQUISITION PROCEDURES Fast Payment...

  15. 48 CFR 213.402 - Conditions for use.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Conditions for use. 213.402 Section 213.402 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SIMPLIFIED ACQUISITION PROCEDURES Fast Payment...

  16. 48 CFR 213.402 - Conditions for use.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Conditions for use. 213.402 Section 213.402 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SIMPLIFIED ACQUISITION PROCEDURES Fast Payment...

  17. 48 CFR 213.402 - Conditions for use.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Conditions for use. 213.402 Section 213.402 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SIMPLIFIED ACQUISITION PROCEDURES Fast Payment...

  18. 18 CFR 2.13 - Design and construction.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Design and construction. 2.13 Section 2.13 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND INTERPRETATIONS Statements of General Policy and...

  19. 18 CFR 2.13 - Design and construction.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Design and construction. 2.13 Section 2.13 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND INTERPRETATIONS Statements of General Policy and...

  20. 18 CFR 2.13 - Design and construction.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Design and construction. 2.13 Section 2.13 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND INTERPRETATIONS Statements of General Policy and...

  1. 18 CFR 2.13 - Design and construction.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Design and construction. 2.13 Section 2.13 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND INTERPRETATIONS Statements of General Policy and...

  2. 49 CFR 37.213 - Information collection requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Analysis & Information System 1200 New Jersey Avenue, SE., Washington, D.C. 20590. [66 FR 9053, Feb. 6... 49 Transportation 1 2011-10-01 2011-10-01 false Information collection requirements. 37.213... INDIVIDUALS WITH DISABILITIES (ADA) Over-the-Road Buses (OTRBs) § 37.213 Information collection requirements...

  3. 25 CFR 213.33 - Diligence and prevention of waste.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Diligence and prevention of waste. 213.33 Section 213.33... LANDS OF MEMBERS OF FIVE CIVILIZED TRIBES, OKLAHOMA, FOR MINING Operations § 213.33 Diligence and prevention of waste. The lessee shall exercise diligence in drilling and operating wells for oil and gas on...

  4. UV irradiation experiments under simulated martian surface conditions: Bio-effects on glycine, phage T7 and isolated T7 DNA

    NASA Astrophysics Data System (ADS)

    Bérces, Attila; ten Kate, I. L.; Fekete, A.; Hegedus, M.; Garry, J. R. C.; Lammer, Helmut; Ehrenfreund, Pascale; Peeters, Zan; Kovacs, G.; Ronto, G.

    Mars is considered as a main target for astrobiologically relevant exploration programmes. In order to explain the non-detection of organic material to a detection level of several parts per billion (ppb) by the Viking landers, several hypotheses have been suggested, including degradation processes occurring on the martian surface and in the martian soil and subsurface. UV exposure experiments have been performed in which thin layers of glycine ( 300 nm), and aqueous suspensions of phage T7 and isolated T7 DNA were irradiated with a Deuterium lamp and for comparison with a Xenon arc lamp, modified to simulate the solar irradiation on the surface of Mars (MarsUV). The glycine sample was subjected to 24 hours of irradiation with MarsUV. The results of this glycine experiment show a destruction rate comparable to the results of previous experiments in which thin layers of glycine were irradiated with a deuterium lamp (ten Kate et al., 2005, 2006). After exposure of different doses of simulated Martian UV radiation a decrease of the biological activity of phages and characteristic changes in the UV absorption spectrum have been detected, indicating the UV damage of isolated and intraphage T7 DNA. The results of our experiments show that intraphage DNA is 4 times more sensitive to simulated martian UV and deuterium lamp radiation than isolated T7 DNA. This result indicates the significant role that phage proteins play in the UV damage. The effect of simulated martian radiation is smaller than the biological defects observed after the exposure with a deuterium lamp for both cases, in intraphage and isolated DNA, despite of the 100 times larger intensity of the MarsUV lamp. The detected spectral differences are about ten times smaller; the biological activity is about 3 - 4 times smaller, indicating that the shorter wavelength UV radiation from the deuterium lamp is more effective in inducing DNA damage, irrespective of being intraphage or isolated.

  5. Multiband Spectral-Spatial RF Excitation for Hyperpolarized [2-13C]Dihydroxyacetone 13C-MR Metabolism Studies

    PubMed Central

    Marco-Rius, Irene; Cao, Peng; von Morze, Cornelius; Merrit, Matthew; Moreno, Karlos X; Chang, Gene-Yuan; Ohliger, Michael A.; Pearce, David; Kurhanewicz, John; Larson, Peder E. Z.; Vigneron, Daniel B.

    2016-01-01

    Purpose To develop a specialized multislice, single-acquisition approach to detect the metabolites of hyperpolarized [2-13C]dihydroxyacetone (DHAc) to probe gluconeogenesis in vivo, which have a broad 144 ppm spectral range (~4.6 KHz at 3T). A novel multiband RF excitation pulse was designed for independent flip angle control over 5-6 spectral-spatial (SPSP) excitation bands, each corrected for chemical shift misregistration effects. Methods Specialized multi-band SPSP RF pulses were designed, tested and applied to investigate hyperpolarized [2-13C]DHAc metabolism in kidney and liver of fasted rats with dynamic 13C-MRS and an optimal flip angle scheme. For comparison, experiments were also performed with narrow-band slice-selective RF pulses and a sequential change of the frequency offset to cover the five frequency bands of interest. Results The SPSP pulses provided a controllable spectral profile free of baseline distortion with improved signal to noise of the metabolite peaks, allowing for quantification of the metabolic products. We observed organ-specific differences in DHAc metabolism. There was 2-5 times more [2-13C]phosphoenolpyruvate and about 19 times more [2-13C]glycerol 3-phosphate in the liver than in the kidney. Conclusion A multiband SPSP RF pulse covering a spectral range over 144 ppm enabled in vivo characterization of HP [2-13C]dihydroxyacetone metabolism in rat liver and kidney. PMID:27017966

  6. 40 CFR 86.213-94 - Fuel specifications.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 19 2012-07-01 2012-07-01 false Fuel specifications. 86.213-94 Section...-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.213-94 Fuel specifications. Gasoline... manufacturer and shall be made available to the Administrator upon request. Table—Cold CO Fuel Specifications...

  7. 40 CFR 86.213-94 - Fuel specifications.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 18 2011-07-01 2011-07-01 false Fuel specifications. 86.213-94 Section...-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.213-94 Fuel specifications. Gasoline... manufacturer and shall be made available to the Administrator upon request. Table—Cold CO Fuel Specifications...

  8. 40 CFR 86.213-94 - Fuel specifications.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 19 2013-07-01 2013-07-01 false Fuel specifications. 86.213-94 Section...-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.213-94 Fuel specifications. Gasoline... manufacturer and shall be made available to the Administrator upon request. Table—Cold CO Fuel Specifications...

  9. 12 CFR Appendix A to Part 213 - Model Forms

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Model Forms A Appendix A to Part 213 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM CONSUMER LEASING (REGULATION M) Pt. 213, App. A Appendix A to Part 213—Model Forms A-1Model Open-End or Finance Vehicle Lease...

  10. 12 CFR Appendix A to Part 213 - Model Forms

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 2 2011-01-01 2011-01-01 false Model Forms A Appendix A to Part 213 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM CONSUMER LEASING (REGULATION M) Pt. 213, App. A Appendix A to Part 213—Model Forms A-1Model Open-End or Finance Vehicle Lease...

  11. 13 CFR 500.213 - Termination of obligations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Termination of obligations. 500.213 Section 500.213 Business Credit and Assistance EMERGENCY OIL AND GAS GUARANTEED LOAN BOARD... the Application, the Guarantee or the Loan Documents; (5) A Lender fails to make a demand for payment...

  12. 40 CFR 86.213-04 - Fuel specifications.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 19 2013-07-01 2013-07-01 false Fuel specifications. 86.213-04 Section...-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.213-04 Fuel specifications. Gasoline... manufacturer and must be made available to the Administrator upon request. The table listing the cold CO fuel...

  13. 40 CFR 86.213-04 - Fuel specifications.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 18 2011-07-01 2011-07-01 false Fuel specifications. 86.213-04 Section...-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.213-04 Fuel specifications. Gasoline... manufacturer and must be made available to the Administrator upon request. The table listing the cold CO fuel...

  14. 40 CFR 86.213-04 - Fuel specifications.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 19 2012-07-01 2012-07-01 false Fuel specifications. 86.213-04 Section...-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.213-04 Fuel specifications. Gasoline... manufacturer and must be made available to the Administrator upon request. The table listing the cold CO fuel...

  15. 48 CFR 213.305 - Imprest funds and third party drafts.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Imprest funds and third party drafts. 213.305 Section 213.305 Federal Acquisition Regulations System DEFENSE ACQUISITION... PROCEDURES Simplified Acquisition Methods 213.305 Imprest funds and third party drafts. ...

  16. 48 CFR 213.305 - Imprest funds and third party drafts.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Imprest funds and third party drafts. 213.305 Section 213.305 Federal Acquisition Regulations System DEFENSE ACQUISITION... PROCEDURES Simplified Acquisition Methods 213.305 Imprest funds and third party drafts. ...

  17. 48 CFR 213.305 - Imprest funds and third party drafts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Imprest funds and third party drafts. 213.305 Section 213.305 Federal Acquisition Regulations System DEFENSE ACQUISITION... PROCEDURES Simplified Acquisition Methods 213.305 Imprest funds and third party drafts. ...

  18. 48 CFR 213.305 - Imprest funds and third party drafts.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Imprest funds and third party drafts. 213.305 Section 213.305 Federal Acquisition Regulations System DEFENSE ACQUISITION... PROCEDURES Simplified Acquisition Methods 213.305 Imprest funds and third party drafts. ...

  19. 48 CFR 213.305 - Imprest funds and third party drafts.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Imprest funds and third party drafts. 213.305 Section 213.305 Federal Acquisition Regulations System DEFENSE ACQUISITION... PROCEDURES Simplified Acquisition Methods 213.305 Imprest funds and third party drafts. ...

  20. Irradiation performance of PFBR MOX fuel after 112 GWd/t burn-up

    NASA Astrophysics Data System (ADS)

    Venkiteswaran, C. N.; Jayaraj, V. V.; Ojha, B. K.; Anandaraj, V.; Padalakshmi, M.; Vinodkumar, S.; Karthik, V.; Vijaykumar, Ran; Vijayaraghavan, A.; Divakar, R.; Johny, T.; Joseph, Jojo; Thirunavakkarasu, S.; Saravanan, T.; Philip, John; Rao, B. P. C.; Kasiviswanathan, K. V.; Jayakumar, T.

    2014-06-01

    The 500 MWe Prototype Fast Breeder Reactor (PFBR) which is in advanced stage of construction at Kalpakkam, India, will use mixed oxide (MOX) fuel with a target burnup of 100 GWd/t. The fuel pellet is of annular design to enable operation at a peak linear power of 450 W/cm with the requirement of minimum duration of pre-conditioning. The performance of the MOX fuel and the D9 clad and wrapper material was assessed through Post Irradiation Examinations (PIE) after test irradiation of 37 fuel pin subassembly in Fast Breeder Test Reactor (FBTR) to a burn-up of 112 GWd/t. Fission product distribution, swelling and fuel-clad gap evolution, central hole diameter variation, restructuring, fission gas release and clad wastage due to fuel-clad chemical interaction were evaluated through non-destructive and destructive examinations. The examinations have indicated that the MOX fuel can safely attain the desired target burn-up in PFBR.

  1. 5 CFR 213.3402 - Entire executive civil service; Pathways Programs.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Entire executive civil service; Pathways Programs. 213.3402 Section 213.3402 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS EXCEPTED SERVICE Excepted Schedules Schedule D § 213.3402 Entire executive civil service; Pathways...

  2. 5 CFR 213.3402 - Entire executive civil service; Pathways Programs.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Entire executive civil service; Pathways Programs. 213.3402 Section 213.3402 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS EXCEPTED SERVICE Excepted Schedules Schedule D § 213.3402 Entire executive civil service; Pathways...

  3. 49 CFR Appendix B to Part 213 - Schedule of Civil Penalties

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Automated vehicle-based inspection systems 5,000 7,500 213.335 Crossties (a) Material used 1,000 2,000 (b... 213.234 Automated inspection of track constructed with concrete crossties 5,000 7,500 213.235 Switches... (a) through (h) 5,000 7,500 213.345 Vehicle/track system qualification: (a) through (d) 5,000 7,500...

  4. Prolonged survival in secondary glioblastoma following local injection of targeted alpha therapy with 213Bi-substance P analogue.

    PubMed

    Krolicki, Leszek; Bruchertseifer, Frank; Kunikowska, Jolanta; Koziara, Henryk; Królicki, Bartosz; Jakuciński, Maciej; Pawlak, Dariusz; Apostolidis, Christos; Mirzadeh, Saed; Rola, Rafał; Merlo, Adrian; Morgenstern, Alfred

    2018-04-30

    Glioblastoma multiforme (GBM), the most common malignant brain tumor, mainly manifests as a primary de novo and less frequently as a secondary glial neoplasm. GBM has been demonstrated to overexpress the NK-1 receptor and substance P can be used as a ligand for targeted therapy. Alpha emitters, e.g. 213 Bi, that deposit their high energy within a short range allow the selective irradiation of tumor cells while sparing adjacent neuronal structures. Among 50 glioma patients of different subtypes that have to date been treated with targeted alpha therapy at the Medical University Warsaw, we report here the data on nine patients with secondary GBM. Following surgery, chemo- and radiotherapy, recurrent GBM was treated by intracavitary injection of 1-6 doses of 0.9-2.3 GBq 213 Bi- DOTA-[Thi 8 ,Met(O 2 ) 11 ]-substance P ( 213 Bi-DOTA-SP) in 2-month intervals. 68 Ga-DOTA-[Thi 8 ,Met(O 2 ) 11 ]-substance P ( 68 Ga-DOTA-SP) was co-injected with the therapeutic doses to assess biodistribution using PET/CT. Therapeutic response was monitored with MRI. Treatment with activities ranging from 1.4 to 9.7 (median 5.8) GBq 213 Bi- DOTA-SP was well tolerated with only mild transient adverse reactions, mainly headaches due to a transient perfocal edema reaction. The median progression free survival and overall survival time following the initiation of alpha therapy was 5.8 and 16.4 months, respectively. The median overall survival time from the first diagnosis was 52.3 months. Two out of nine patients are still alive 39 and 51 months, respectively, after the initiation of the therapy. Targeted alpha therapy of secondary GBM with 213 Bi-DOTA-SP is safe and well tolerated and may evolve as a promising novel therapeutic option for secondary GBM.

  5. 49 CFR Appendix C to Part 213 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false [Reserved] C Appendix C to Part 213 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION TRACK SAFETY STANDARDS Appendix C to Part 213[Reserved] ...

  6. 49 CFR 213.352 - Torch cut rail.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Torch cut rail. 213.352 Section 213.352... Torch cut rail. (a) Except as a temporary repair in emergency situations no rail having a torch cut end shall be used. When a rail end with a torch cut is used in emergency situations, train speed over that...

  7. 49 CFR 213.352 - Torch cut rail.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Torch cut rail. 213.352 Section 213.352... Torch cut rail. (a) Except as a temporary repair in emergency situations no rail having a torch cut end shall be used. When a rail end with a torch cut is used in emergency situations, train speed over that...

  8. 49 CFR 384.213 - State penalties for drivers of CMVs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 5 2012-10-01 2012-10-01 false State penalties for drivers of CMVs. 384.213 Section 384.213 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR... § 384.213 State penalties for drivers of CMVs. The State must impose on drivers of CMVs appropriate...

  9. 49 CFR 384.213 - State penalties for drivers of CMVs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 5 2011-10-01 2011-10-01 false State penalties for drivers of CMVs. 384.213 Section 384.213 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR... § 384.213 State penalties for drivers of CMVs. The State must impose on drivers of CMVs appropriate...

  10. 49 CFR 384.213 - State penalties for drivers of CMVs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 5 2014-10-01 2014-10-01 false State penalties for drivers of CMVs. 384.213 Section 384.213 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR... § 384.213 State penalties for drivers of CMVs. The State must impose on drivers of CMVs appropriate...

  11. 49 CFR 384.213 - State penalties for drivers of CMVs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 5 2013-10-01 2013-10-01 false State penalties for drivers of CMVs. 384.213 Section 384.213 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR... § 384.213 State penalties for drivers of CMVs. The State must impose on drivers of CMVs appropriate...

  12. 49 CFR 384.213 - State penalties for drivers of CMVs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false State penalties for drivers of CMVs. 384.213 Section 384.213 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR... § 384.213 State penalties for drivers of CMVs. The State must impose on drivers of CMVs appropriate...

  13. 49 CFR 213.347 - Automotive or railroad crossings at grade.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Automotive or railroad crossings at grade. 213.347 Section 213.347 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... Higher § 213.347 Automotive or railroad crossings at grade. (a) There shall be no at-grade (level...

  14. 49 CFR 213.347 - Automotive or railroad crossings at grade.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Automotive or railroad crossings at grade. 213.347 Section 213.347 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... Higher § 213.347 Automotive or railroad crossings at grade. (a) There shall be no at-grade (level...

  15. 49 CFR 213.347 - Automotive or railroad crossings at grade.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Automotive or railroad crossings at grade. 213.347 Section 213.347 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... Higher § 213.347 Automotive or railroad crossings at grade. (a) There shall be no at-grade (level...

  16. 49 CFR 213.347 - Automotive or railroad crossings at grade.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Automotive or railroad crossings at grade. 213.347 Section 213.347 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... Higher § 213.347 Automotive or railroad crossings at grade. (a) There shall be no at-grade (level...

  17. 17DD and 17D-213/77 yellow fever substrains trigger a balanced cytokine profile in primary vaccinated children.

    PubMed

    Campi-Azevedo, Ana Carolina; de Araújo-Porto, Luiza Pacheco; Luiza-Silva, Maria; Batista, Maurício Azevedo; Martins, Marina Angela; Sathler-Avelar, Renato; da Silveira-Lemos, Denise; Camacho, Luiz Antonio Bastos; de Menezes Martins, Reinaldo; de Lourdes de Sousa Maia, Maria; Farias, Roberto Henrique Guedes; da Silva Freire, Marcos; Galler, Ricardo; Homma, Akira; Ribeiro, José Geraldo Leite; Lemos, Jandira Aparecida Campos; Auxiliadora-Martins, Maria; Caldas, Iramaya Rodrigues; Elói-Santos, Silvana Maria; Teixeira-Carvalho, Andréa; Martins-Filho, Olindo Assis

    2012-01-01

    This study aimed to compare the cytokine-mediated immune response in children submitted to primary vaccination with the YF-17D-213/77 or YF-17DD yellow fever (YF) substrains. A non-probabilistic sample of eighty healthy primary vaccinated (PV) children was selected on the basis of their previously known humoral immune response to the YF vaccines. The selected children were categorized according to their YF-neutralizing antibody titers (PRNT) and referred to as seroconverters (PV-PRNT(+)) or nonseroconverters (PV-PRNT(-)). Following revaccination with the YF-17DD, the PV-PRNT(-) children (YF-17D-213/77 and YF-17DD groups) seroconverted and were referred as RV-PRNT(+). The cytokine-mediated immune response was investigated after short-term in vitro cultures of whole blood samples. The results are expressed as frequency of high cytokine producers, taking the global median of the cytokine index (YF-Ag/control) as the cut-off. The YF-17D-213/77 and the YF-17DD substrains triggered a balanced overall inflammatory/regulatory cytokine pattern in PV-PRNT(+), with a slight predominance of IL-12 in YF-17DD vaccinees and a modest prevalence of IL-10 in YF-17D-213/77. Prominent frequency of neutrophil-derived TNF-α and neutrophils and monocyte-producing IL-12 were the major features of PV-PRNT(+) in the YF-17DD, whereas relevant inflammatory response, mediated by IL-12(+)CD8(+) T cells, was the hallmark of the YF-17D-213/77 vaccinees. Both substrains were able to elicit particular but relevant inflammatory events, regardless of the anti-YF PRNT antibody levels. PV-PRNT(-) children belonging to the YF-17DD arm presented gaps in the inflammatory cytokine signature, especially in terms of the innate immunity, whereas in the YF-17D-213/77 arm the most relevant gap was the deficiency of IL-12-producing CD8(+)T cells. Revaccination with YF-17DD prompted a balanced cytokine profile in YF-17DD nonresponders and a robust inflammatory profile in YF-17D-213/77 nonresponders. Our findings

  18. Mitomycin C-treated or irradiated concanavalin A-activated T cells augment the activation of cytotoxic T cells in vivo.

    PubMed

    Moyers, C; Pottmeyer-Gerber, C; Gerber, M; Buszello, H; Dröge, W

    1984-10-01

    The activation of cytotoxic T lymphocytes (CTL) in vivo after immunization of normal or cyclophosphamide-treated mice with allogeneic cells was strongly augmented by the administration of mitomycin C-treated or irradiated concanavalin A-activated spleen cells (Con A-spl). This effect of the Con A-spl was abrogated by treatment with Anti-Thy 1 antibody plus complement, and was therefore presumably mediated by activated "helper" T cells. (The term "helper" cell is only operationally defined in this context and indicates that the augmenting irradiation resistant T cells are obviously not CTL precursor cells). These observations indicated (i) that even the cytotoxic response against allogeneic stimulator cells suffers in vivo from insufficient "helper" T cell activity, and (ii) that the injection of Con A-spl may serve as a simple procedure to apply this "helper" activity in vivo. This procedure was at least as effective as the repeated injection of interleukin 2 (IL-2)-containing cell supernatants with up to four 30-unit doses of IL-2 per mouse. IL-2-containing cell supernatants were found to mediate similar effects only if injected into the footpads but not intravenously. This was in line with the reported observation that IL-2 has an extremely short half-life in vivo. The injection of Con A-spl was also found to augment the proliferative response in the regional lymph nodes.

  19. 12 CFR Appendix B to Part 213 - Federal Enforcement Agencies

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 2 2014-01-01 2014-01-01 false Federal Enforcement Agencies B Appendix B to Part 213 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM CONSUMER LEASING (REGULATION M) Pt. 213, App. B Appendix B to Part 213—Federal Enforcement Agencies The...

  20. Spectral measurements of asymmetrically irradiated capsule backlighters

    DOE PAGES

    Keiter, P. A.; Drake, R. P.

    2016-09-09

    Capsule backlighters provide a quasi-continuum x-ray spectrum over a wide range of photon energies. Ideally one irradiates the capsule backlighter symmetrically, however, in complex experimental geometries, this is not always possible. In recent experiments we irradiated capsule backlighters asymmetrically and measured the x-ray spectrum from multiple directions. We will present time-integrated spectra over the photon energy range of ~2-13 keV and time-resolved spectra over the photon energy range of ~2-3 keV. Lastly, we will compare the spectra from different lines of sight to determine if the laser asymmetry results in an angular dependence in the x-ray emission.

  1. 14 CFR 417.213 - Flight safety limits analysis.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Flight safety limits analysis. 417.213 Section 417.213 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION... launch vehicle's flight to prevent the hazardous effects of the resulting debris impacts from reaching...

  2. 14 CFR 417.213 - Flight safety limits analysis.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Flight safety limits analysis. 417.213 Section 417.213 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION... launch vehicle's flight to prevent the hazardous effects of the resulting debris impacts from reaching...

  3. 14 CFR 417.213 - Flight safety limits analysis.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Flight safety limits analysis. 417.213 Section 417.213 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION... launch vehicle's flight to prevent the hazardous effects of the resulting debris impacts from reaching...

  4. 14 CFR 417.213 - Flight safety limits analysis.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Flight safety limits analysis. 417.213 Section 417.213 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION... launch vehicle's flight to prevent the hazardous effects of the resulting debris impacts from reaching...

  5. 14 CFR 417.213 - Flight safety limits analysis.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Flight safety limits analysis. 417.213 Section 417.213 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION... launch vehicle's flight to prevent the hazardous effects of the resulting debris impacts from reaching...

  6. 49 CFR Appendix B to Part 213 - Schedule of Civil Penalties

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...,500 213.333 Automated vehicle inspection systems 5,000 7,500 213.335 Crossties (a) Material used 1,000....343 Continuous welded rail (a) through (h) 5,000 7,500 213.345 Vehicle qualification testing (a...

  7. The two single nucleotide polymorphisms in the H37/RBM5 tumour suppressor gene at 3p21.3 correlated with different subtypes of non-small cell lung cancers

    PubMed Central

    Oh, Juliana J.; Koegel, Ashley; Phan, Diana T.; Razfar, Ali; Slamon, Dennis J.

    2007-01-01

    Summary Allele loss and genetic alteration in chromosome 3p, particularly in 3p21.3 region, are the most frequent and the earliest genomic abnormalities found in lung cancer. Multiple 3p21.3 genes exhibit various degrees of tumour suppression activity suggesting that 3p21.3 genes may function as an integrated tumour suppressor region through their diverse biological activities. We have previously demonstrated growth inhibitory effects and tumour suppression mechanism of the H37/RBM5 gene which is one of the 19 genes residing in the 370kb minimal overlap region at 3p21.3. In the current study, in an attempt to find, if any, mutations in the H37 coding region in lung cancer cells, we compared nucleotide sequences of the entire H37 gene in tumour vs. adjacent normal tissues from 17 non-small cell lung cancer (NSCLC) patients. No mutations were detected, instead, we found the two silent single nucleotide polymorphisms (SNPs), C1138T and C2185T, within the coding region of the H37 gene. In addition, we found that specific allele types at these SNP positions are correlated with different histological subtypes of NSCLC; tumours containing heterozygous alleles (C+T) at these SNP positions are more likely to be associated with adenocarcinoma (AC) whereas homozygous alleles (either C or T) are associated with squamous cell carcinoma (SCC) (p=0.0098). We postulate that, these two silent polymorphisms may be in linkage disequilibrium (LD) with a disease causative allele in the 3p21.3 tumour suppressor region which is packed with a large number of important genes affecting lung cancer development. In addition, because of prevalent loss of heterozygosity (LOH) detected at 3p21.3 which precedes lung cancer initiation, these SNPs may be developed into a marker screening for the high risk individuals. PMID:17606309

  8. Process and apparatus for the production of BI-213 cations

    DOEpatents

    Horwitz, E. Philip; Hines, John J.; Chiarizia, Renato; Dietz, Mark

    1998-01-01

    A process for producing substantially impurity-free Bi-213 cations is disclosed. An aqueous acid feed solution containing Ac-225 cations is contacted with an ion exchange medium to bind the Ac-225 cations and form an Ac-225-laden ion exchange medium. The bound Ac-225 incubates on the ion exchange medium to form Bi-213 cations by radioactive decay. The Bi-213 cations are then recovered from the Ac-225-laden ion exchange medium to form a substantially impurity-free aqueous Bi-213 cation acid solution. An apparatus for carrying out this process is also disclosed.

  9. Process and apparatus for the production of Bi-213 cations

    DOEpatents

    Horwitz, E.P.; Hines, J.J.; Chiarizia, R.; Dietz, M.

    1998-12-29

    A process for producing substantially impurity-free Bi-213 cations is disclosed. An aqueous acid feed solution containing Ac-225 cations is contacted with an ion exchange medium to bind the Ac-225 cations and form an Ac-225-laden ion exchange medium. The bound Ac-225 incubates on the ion exchange medium to form Bi-213 cations by radioactive decay. The Bi-213 cations are then recovered from the Ac-225-laden ion exchange medium to form a substantially impurity-free aqueous Bi-213 cation acid solution. An apparatus for carrying out this process is also disclosed. 7 figs.

  10. 25 CFR 213.14 - Corporations and corporate information.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Corporations and corporate information. 213.14 Section 213... Corporations and corporate information. If the applicant for a lease is a corporation, it shall file evidence..., evidence showing compliance with the corporation laws thereof. Statements of changes in officers and...

  11. 14 CFR 93.213 - Definitions and general provisions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Definitions and general provisions. 93.213 Section 93.213 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION..., as specified in subpart K of this part. (3) Summer season means the period of time from the first...

  12. 14 CFR 93.213 - Definitions and general provisions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false Definitions and general provisions. 93.213 Section 93.213 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION..., as specified in subpart K of this part. (3) Summer season means the period of time from the first...

  13. 14 CFR 93.213 - Definitions and general provisions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false Definitions and general provisions. 93.213 Section 93.213 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION..., as specified in subpart K of this part. (3) Summer season means the period of time from the first...

  14. 14 CFR 93.213 - Definitions and general provisions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false Definitions and general provisions. 93.213 Section 93.213 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION..., as specified in subpart K of this part. (3) Summer season means the period of time from the first...

  15. 25 CFR 213.43 - Relinquishment of Government supervision.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Relinquishment of Government supervision. 213.43 Section 213.43 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEASING OF... Relinquishment of Government supervision. All oil and gas leases hereafter executed shall contain the following...

  16. 25 CFR 213.43 - Relinquishment of Government supervision.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Relinquishment of Government supervision. 213.43 Section 213.43 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEASING OF... Relinquishment of Government supervision. All oil and gas leases hereafter executed shall contain the following...

  17. 25 CFR 213.43 - Relinquishment of Government supervision.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Relinquishment of Government supervision. 213.43 Section 213.43 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEASING OF... Relinquishment of Government supervision. All oil and gas leases hereafter executed shall contain the following...

  18. 25 CFR 213.43 - Relinquishment of Government supervision.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Relinquishment of Government supervision. 213.43 Section 213.43 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEASING OF... Relinquishment of Government supervision. All oil and gas leases hereafter executed shall contain the following...

  19. 25 CFR 213.43 - Relinquishment of Government supervision.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Relinquishment of Government supervision. 213.43 Section 213.43 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEASING OF... Relinquishment of Government supervision. All oil and gas leases hereafter executed shall contain the following...

  20. 45 CFR 213.2 - Records to be public.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Records to be public. 213.2 Section 213.2 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES PRACTICE AND PROCEDURE FOR...

  1. 45 CFR 213.2 - Records to be public.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 2 2011-10-01 2011-10-01 false Records to be public. 213.2 Section 213.2 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES PRACTICE AND PROCEDURE FOR...

  2. 45 CFR 213.2 - Records to be public.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true Records to be public. 213.2 Section 213.2 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES PRACTICE AND PROCEDURE FOR...

  3. 45 CFR 213.2 - Records to be public.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 2 2012-10-01 2012-10-01 false Records to be public. 213.2 Section 213.2 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES PRACTICE AND PROCEDURE FOR...

  4. 45 CFR 213.2 - Records to be public.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 2 2014-10-01 2012-10-01 true Records to be public. 213.2 Section 213.2 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES PRACTICE AND PROCEDURE FOR...

  5. 8 CFR 213a.2 - Use of affidavit of support.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Form I-864, Affidavit of Support Under Section 213A of the Act, in accordance with section 213A of the Act, this section, and the instructions on Form I-864. The sponsor may use the Form I-864EZ, EZ Affidavit of Support Under Section 213A of the Act, rather than the Form I-864, if the sponsor meets the...

  6. The immunogenicity of phagocytosed T4 bacteriophage: cell replacement studies with splenectomized and irradiated mice

    PubMed Central

    Inchley, C. J.; Howard, J. G.

    1969-01-01

    The role of phagocytosed antigen in the production of antibody to bacteriophage T4 has been studied. The ability of mice to give an antibody response to this antigen was first impaired either by splenectomy or by X-irradiation, and then restored by injection of syngeneic lymphoid cells given at various times relative to the injection of T4. In splenectomized animals administration of lymphoid cells had only a marginal effect on the severely depressed response to T4. It was concluded that the presence of an intact spleen is essential to the development of the normal immune response, and that circulating immunocompetent cells are unable to respond to circulating antigen or to antigen sequestered within the liver. On the other hand, in irradiated mice, there was a faster and more complete restoration of the anti-T4 response, confirming the ability of antigen localized within the spleen to stimulate competent cells. It was also found that the immunogenicity of T4 within this organ was not lost at a rate which corresponded to its gross breakdown but persisted without decrease for at least 48 hr. A similar observation was made for sheep red blood cells when this antigen was used in conjunction with T4. PMID:5370054

  7. 50 CFR 216.213 - Permissible methods of taking.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 10 2012-10-01 2012-10-01 false Permissible methods of taking. 216.213 Section 216.213 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC... methods of taking. The Holder of a Letter of Authorization issued pursuant to § 216.218, may incidentally...

  8. 14 CFR 135.213 - Weather reports and forecasts.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Weather reports and forecasts. 135.213... Operating Limitations and Weather Requirements § 135.213 Weather reports and forecasts. (a) Whenever a person operating an aircraft under this part is required to use a weather report or forecast, that person...

  9. 14 CFR 135.213 - Weather reports and forecasts.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Weather reports and forecasts. 135.213... Operating Limitations and Weather Requirements § 135.213 Weather reports and forecasts. (a) Whenever a person operating an aircraft under this part is required to use a weather report or forecast, that person...

  10. 14 CFR 135.213 - Weather reports and forecasts.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Weather reports and forecasts. 135.213... Operating Limitations and Weather Requirements § 135.213 Weather reports and forecasts. (a) Whenever a person operating an aircraft under this part is required to use a weather report or forecast, that person...

  11. 14 CFR 135.213 - Weather reports and forecasts.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Weather reports and forecasts. 135.213... Operating Limitations and Weather Requirements § 135.213 Weather reports and forecasts. (a) Whenever a person operating an aircraft under this part is required to use a weather report or forecast, that person...

  12. 14 CFR 135.213 - Weather reports and forecasts.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Weather reports and forecasts. 135.213... Operating Limitations and Weather Requirements § 135.213 Weather reports and forecasts. (a) Whenever a person operating an aircraft under this part is required to use a weather report or forecast, that person...

  13. 22 CFR 213.21 - Employee salary offset-general.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Employee salary offset-general. 213.21 Section... § 213.21 Employee salary offset—general. (a) Purpose. This section establishes USAID's policies and... account of an employee. (b) Scope. The provisions of this section apply to collection by salary offset...

  14. 49 CFR 213.333 - Automated vehicle inspection systems.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Automated vehicle inspection systems. 213.333... Higher § 213.333 Automated vehicle inspection systems. (a) For track Class 7, a qualifying Track Geometry Measurement System (TGMS) vehicle shall be operated at least twice within 120 calendar days with not less than...

  15. 24 CFR 213.266a - Insurance fund obligations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Insurance fund obligations. 213... Insurance fund obligations. A mortgage endorsed for insurance under section 213 of the Act shall be the obligation either of the Cooperative Management Housing Insurance Fund or of the General Insurance Fund. The...

  16. 48 CFR 1553.213 - Small purchases and other simplified purchase procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Small purchases and other simplified purchase procedures. 1553.213 Section 1553.213 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY CLAUSES AND FORMS FORMS Prescription of Forms 1553.213 Small purchases and other...

  17. 14 CFR 302.213 - Procedures in foreign air carrier permit cases.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... cases. 302.213 Section 302.213 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF... Applications § 302.213 Procedures in foreign air carrier permit cases. (a) Applicability. This section applies to cases involving foreign air carrier permits under section 41302 of the Statute, including...

  18. 14 CFR 302.213 - Procedures in foreign air carrier permit cases.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... cases. 302.213 Section 302.213 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF... Applications § 302.213 Procedures in foreign air carrier permit cases. (a) Applicability. This section applies to cases involving foreign air carrier permits under section 41302 of the Statute, including...

  19. Enzymatic characteristics of I213T mutant presenilin-1/gamma-secretase in cell models and knock-in mouse brains: familial Alzheimer disease-linked mutation impairs gamma-site cleavage of amyloid precursor protein C-terminal fragment beta.

    PubMed

    Shimojo, Masafumi; Sahara, Naruhiko; Mizoroki, Tatsuya; Funamoto, Satoru; Morishima-Kawashima, Maho; Kudo, Takashi; Takeda, Masatoshi; Ihara, Yasuo; Ichinose, Hiroshi; Takashima, Akihiko

    2008-06-13

    Presenilin (PS)/gamma-secretase-mediated intramembranous proteolysis of amyloid precursor protein produces amyloid beta (Abeta) peptides in which Abeta species of different lengths are generated through multiple cleavages at the gamma-, zeta-, and epsilon-sites. An increased Abeta42/Abeta40 ratio is a common characteristic of most cases of familial Alzheimer disease (FAD)-linked PS mutations. However, the molecular mechanisms underlying amyloid precursor protein proteolysis leading to increased Abeta42/Abeta40 ratios still remain unclear. Here, we report our findings on the enzymatic analysis of gamma-secretase derived from I213T mutant PS1-expressing PS1/PS2-deficient (PS(-/-)) cells and from the brains of I213T mutant PS1 knock-in mice. Kinetics analyses revealed that the FAD mutation reduced de novo Abeta generation, suggesting that mutation impairs the total catalytic rate of gamma-secretase. Analysis of each Abeta species revealed that the FAD mutation specifically reduced Abeta40 levels more drastically than Abeta42 levels, leading to an increased Abeta42/Abeta40 ratio. By contrast, the FAD mutation increased the generation of longer Abeta species such as Abeta43, Abeta45, and >Abeta46. These results were confirmed by analyses of gamma-secretase derived from I213T knock-in mouse brains, in which the reduction of de novo Abeta generation was mutant allele dose-dependent. Our findings clearly indicate that the mechanism underlying the increased Abeta42/Abeta40 ratio observed in cases of FAD mutations is related to the differential inhibition of gamma-site cleavage reactions, in which the reaction producing Abeta40 is subject to more inhibition than that producing Abeta42. Our results also provide novel insight into how enhancing the generation of longer Abetas may contribute to Alzheimer disease onset.

  20. 15 CFR 904.213 - Settlements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS CIVIL PROCEDURES Hearing and Appeal Procedures General § 904.213 Settlements. If settlement is reached before the Judge has...

  1. 12 CFR 347.213 - Establishment or operation of noninsured foreign branch.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Establishment or operation of noninsured foreign branch. 347.213 Section 347.213 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND STATEMENTS OF GENERAL POLICY INTERNATIONAL BANKING Foreign Banks § 347.213 Establishment or...

  2. 22 CFR 213.38 - Mandatory transfer of debts to FMS-general.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Mandatory transfer of debts to FMS-general. 213.38 Section 213.38 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT CLAIMS COLLECTION Mandatory Transfer of Delinquent Debt to Financial Management Service (FMS) of the Department of Treasury § 213.38...

  3. 30 CFR 250.213 - What general information must accompany the EP?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false What general information must accompany the EP? 250.213 Section 250.213 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND... SHELF Plans and Information Contents of Exploration Plans (ep) § 250.213 What general information must...

  4. 20 CFR 410.213 - Duration of entitlement; child.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Duration of entitlement; child. 410.213...; Filing of Claims and Evidence § 410.213 Duration of entitlement; child. (a) An individual is entitled to benefits as a child for each month beginning with the first month in which all of the conditions of...

  5. 20 CFR 410.213 - Duration of entitlement; child.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Duration of entitlement; child. 410.213...; Filing of Claims and Evidence § 410.213 Duration of entitlement; child. (a) An individual is entitled to benefits as a child for each month beginning with the first month in which all of the conditions of...

  6. 51g-s-213

    NASA Image and Video Library

    2011-04-25

    51G-S-213 (June 1985) --- Public Affairs Office (PAO) commentator Janet K. Ross is pictured at her console in the Mission Operations Control Room (MOCR) in the Mission Control Center at NASA's Johnson Space Center during the STS-51G mission. Photo credit: NASA

  7. B{sub 4}C protective coating under irradiation by QSPA-T intensive plasma fluxes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Buzhinskij, O. I.; Barsuk, V. A.; Begrambekov, L. B., E-mail: lbb@plasma.mephi.ru

    The effect of the QSPA-T pulsed plasma irradiation on the crystalline boron carbide B{sub 4}C coating was examined. The duration of the rectangular plasma pulses was 0.5 ms with an interval of 5–10 min between pulses. The maximum power density in the central part of plasma stream was 1 GW/m{sup 2}. The coating thickness varied from 20 to 40 μm on different surface areas. Modification of the surface layers and transformation of the coating at elevated temperature under plasma pulse irradiation during four successive series of impulses are described. It is shown that the boron carbide coating withstood the fullmore » cycle of tests under irradiation with 100 plasma pulses with peak power density of 1GW/m{sup 2}. Constitutive surface deterioration was not detected and the boron carbide coating kept crystal structure B{sub 4}C throughout the irradiation zone at the surface depth no less 2 μm.« less

  8. 25 CFR 213.19 - Crediting advance annual payments.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... been made. No refund of such advance payments made under any lease will be allowed in the event the royalty on production is not sufficient to equal such advance payment; nor will any part of the moneys so... 25 Indians 1 2010-04-01 2010-04-01 false Crediting advance annual payments. 213.19 Section 213.19...

  9. 25 CFR 213.17 - Government reserves right to purchase minerals produced.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Government reserves right to purchase minerals produced. 213.17 Section 213.17 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS... Leases § 213.17 Government reserves right to purchase minerals produced. In time of war or other public...

  10. 25 CFR 213.17 - Government reserves right to purchase minerals produced.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Government reserves right to purchase minerals produced. 213.17 Section 213.17 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS... Leases § 213.17 Government reserves right to purchase minerals produced. In time of war or other public...

  11. 25 CFR 213.17 - Government reserves right to purchase minerals produced.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Government reserves right to purchase minerals produced. 213.17 Section 213.17 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS... Leases § 213.17 Government reserves right to purchase minerals produced. In time of war or other public...

  12. 25 CFR 213.17 - Government reserves right to purchase minerals produced.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Government reserves right to purchase minerals produced. 213.17 Section 213.17 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS... Leases § 213.17 Government reserves right to purchase minerals produced. In time of war or other public...

  13. SU-E-T-606: Performance of MR-Based 3D FXG Dosimetry for Preclinical Irradiation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Welch, M; Jaffray, D; Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON

    Purpose: Technological advances have revolutionized preclinical radiation research to enable precise radiation delivery in preclinical models. Kilovoltage x-rays and complex geometries in preclinical radiation studies challenge conventional dosimetry methods. Previously developed gel-based dosimetry provides a viable means of accommodating complex geometries and accurately reporting dose at kV energies. This paper will describe the development and evaluation of gel-based ferrous xylenol-orange (FXG) dosimetry using a 7T preclinical imaging system. Methods: To confirm water equivalence, Zeff values were calculated for the FXG material, water and ICRU defined soft tissue. Proton T1 relaxivity response in FXG was measured using a preclinical 7T MRmore » and a small animal irradiator for a dose range of 1–22 Gy. FXG was contained in 50 ml centrifuge tubes and irradiated with a 225 kVp x-ray beam at a nominal dose rate of 2.3 Gy/min. Pre and post irradiation maps of the T1 relaxivity were collected using variable TR spin-echo imaging (TE 6.65 ms; TR 500, 750, 1000, 1500, 2000, 3000 and 5000 ms) with 2 mm thick slices, 0.325 mm/pixel, 3 averages and an acquisition time of 26 minutes. A linear fit to the change in relaxation rate (1/T1) for the delivered doses reported the gel sensitivity in units of ms{sup -1}Gy{sup -1}. Irradiation and imaging studies were repeated using three batches of gel over 72 hrs. Results: FXG has a Zeff of 3.8 for the 225 kVp spectrum used; differing from water and ICRU defined soft tissue by 0.5% and 2.5%, respectively. The average sensitivity for the FXG dosimeter was 31.5 ± 0.7 ms{sup -1}Gy{sup -1} (R{sup 2} = 0.9957) with a y-intercept of −29.4 ± 9.0 ms{sup -1}. Conclusion: Preliminary results for the FXG dosimeter properties, sensitivity, and dose linearity at preclinical energies is promising. Future work will explore anatomically relevant tissue inclusions to test MR performance. Student funding provided by The Terry Fox

  14. IL-15 signaling promotes adoptive effector T-cell survival and memory formation in irradiation-induced lymphopenia.

    PubMed

    Xu, Aizhang; Bhanumathy, Kalpana Kalyanasundaram; Wu, Jie; Ye, Zhenmin; Freywald, Andrew; Leary, Scot C; Li, Rongxiu; Xiang, Jim

    2016-01-01

    Lymphopenia promotes naïve T-cell homeostatic proliferation and adoptive effector T-cell survival and memory formation. IL-7 plays a critical role in homeostatic proliferation, survival and memory formation of naïve T-cells in lymphopenia, and its underlying molecular mechanism has also been well studied. However, the mechanism for adoptively transferred effector T-cell survival and memory formation is not fully understood. Here, we transferred in vitro-activated transgenic OT-I CD8(+) effector T-cells into irradiation (600 rads)-induced lymphopenic C57BL/6, IL-7 knockout (KO) and IL-15 KO mice, and investigated the survival and memory formation of transferred T-cells in lymphopenia. We demonstrate that transferred T-cells prolong their survival and enhance their memory in lymphopenic mice, in a manner that depends on IL-15 signaling, but not IL-7. We determine that in vitro stimulation of naïve or effector T-cells with IL-7 and IL-15 reduces IL-7Rα, and increases and/or maintains IL-15Rβ expression, respectively. Consistent with these findings, the expression of IL-7Rα and IL-15Rβ is down- and up-regulated, respectively, in vivo on transferred T-cells in an early phase post T-cell transfer in lymphopenia. We further show that in vitro IL-15 restimulation-induced memory T-cells (compared to IL-2 restimulation-induced effector T-cells) and in vivo transferred T-cells in irradiated IL-15-sufficient C57BL/6 mice (compared to IL-15-deficient IL-15 KO mice) have increased mitochondrial content, but less NADH and lower mitochondrial potential (ΔΨm), and demonstrate greater phosphorylation of signal transducers and activators of transcription-5 (STAT5) and Unc-51-like kinase-1 (ULK1), and higher expression of B-cell leukemia/lymphoma-2 (Bcl2) and memory-, autophagy- and mitochondrial biogenesis-related molecules. Irradiation-induced lymphopenia promotes effector T-cell survival via IL-15 signaling the STAT5/Bcl2 pathway, enhances T-cell memory formation via IL

  15. 19 CFR 213.3 - Determination of small business eligibility.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Section 213.3 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.3 Determination of small business eligibility. (a... technical assistance from joint applicants, trade associations and unions. If several businesses jointly or...

  16. 19 CFR 213.3 - Determination of small business eligibility.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Section 213.3 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.3 Determination of small business eligibility. (a... technical assistance from joint applicants, trade associations and unions. If several businesses jointly or...

  17. 19 CFR 213.3 - Determination of small business eligibility.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Section 213.3 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.3 Determination of small business eligibility. (a... technical assistance from joint applicants, trade associations and unions. If several businesses jointly or...

  18. 19 CFR 213.3 - Determination of small business eligibility.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Section 213.3 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.3 Determination of small business eligibility. (a... technical assistance from joint applicants, trade associations and unions. If several businesses jointly or...

  19. High-efficency stable 213-nm generation for LASIK application

    NASA Astrophysics Data System (ADS)

    Wang, Zhenglin; Alameh, Kamal; Zheng, Rong

    2005-01-01

    213nm Solid-state laser technology provides an alternative method to replace toxic excimer laser in LASIK system. In this paper, we report a compact fifth harmonic generation system to generate high pulse energy 213nm laser from Q-switched Nd:YAG laser for LASIK application based on three stages harmonic generation procedures. A novel crystal housing was specifically designed to hold the three crystals with each crystal has independent, precise angular adjustment structure and automatic tuning control. The crystal temperature is well maintained at ~130°C to improve harmonic generation stability and crystal operation lifetime. An output pulse energy 35mJ is obtained at 213nm, corresponding to total conversion efficiency ~10% from 1064nm pump laser. In system verification tests, the 213nm output power drops less than 5% after 5 millions pulse shots and no significant damage appears in the crystals.

  20. Investigation of P213S SELL gene polymorphism in type 2 diabetes mellitus and related end stage renal disease. A case-control study.

    PubMed

    Stavarachi, Monica; Panduru, N M; Serafinceanu, C; Moţa, E; Moţa, Maria; Cimponeriu, D; Ion, Daniela Adriana

    2011-01-01

    SELL (L-selectin) is a candidate gene for several complex diseases including diabetes mellitus and renal failure. Our aim was to investigate the involvement of P213S SELL gene polymorphism (rs2229569) in type 2 diabetes mellitus (T2DM) and related end stage renal disease (ESRD). Type 2 diabetes mellitus patients without ESRD (n=250) or with ESRD (n=90), ESRD patients without diabetes (n=119) and sex and age matched healthy subjects (n=459) were analyzed in this study. DNA samples from all these subjects were genotyped for the P213S polymorphism by PCR-RFLP technique. Statistical analysis indicated that SELL P213S genotypes and alleles were similar distributed in the patients and control groups (ORSS=0.37, CI 95%: 0.131>0.372>1.06, p=0.05, Yate's correction p=0.09, for T2DM patients without ESRD, ORSS=2.04, CI 95%: 0.365>2.047>1.465, p=0.4, Yate's correction p=0.67, for T2DM patients with ESRD and ORSS=1, CI95%: 0.198>1>5.057, p=1, Yate's correction p=0.67, for non-diabetic with ESRD patients). Also, no significant differences were noticed when we compared the ESRD subjects with diabetes vs. non-diabetic ones (OR=1.798, CI 95%: 0.392>1.798>8.245, p=0.44, Yate's correction p=0.7). No statistically significant results were found in order to sustain the hypothesis of association between SELL gene P213S polymorphism, type 2 diabetes mellitus and end stage renal disease.

  1. 49 CFR 213.110 - Gage restraint measurement systems.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... applied force from 0 to 4,000 pounds; and (ii) The gage of the track under 4,000 pounds of applied force... requirements specified in §§ 213.109 and 213.127. (5) If the PTLF becomes non-functional or is missing, the... vertical loading of the track is necessary for contact with the lateral rail restraint components, a PTLF...

  2. 49 CFR 213.110 - Gage restraint measurement systems.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... applied force from 0 to 4,000 pounds; and (ii) The gage of the track under 4,000 pounds of applied force... requirements specified in §§ 213.109 and 213.127. (5) If the PTLF becomes non-functional or is missing, the... vertical loading of the track is necessary for contact with the lateral rail restraint components, a PTLF...

  3. 49 CFR 213.110 - Gage restraint measurement systems.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... applied force from 0 to 4,000 pounds; and (ii) The gage of the track under 4,000 pounds of applied force... requirements specified in §§ 213.109 and 213.127. (5) If the PTLF becomes non-functional or is missing, the... vertical loading of the track is necessary for contact with the lateral rail restraint components, a PTLF...

  4. Optimizing labelling conditions of 213Bi-DOTATATE for preclinical applications of peptide receptor targeted alpha therapy.

    PubMed

    Chan, Ho Sze; de Blois, Erik; Konijnenberg, Mark W; Morgenstern, Alfred; Bruchertseifer, Frank; Norenberg, Jeffrey P; Verzijlbergen, Fred J; de Jong, Marion; Breeman, Wouter A P

    2017-01-01

    213 Bismuth ( 213 Bi, T 1/2 = 45.6 min) is one of the most frequently used α-emitters in cancer research. High specific activity radioligands are required for peptide receptor radionuclide therapy. The use of generators containing less than 222 MBq 225 Ac (actinium), due to limited availability and the high cost to produce large-scale 225 Ac/ 213 Bi generators, might complicate in vitro and in vivo applications though.Here we present optimized labelling conditions of a DOTA-peptide with an 225 Ac/ 213 Bi generator (< 222 MBq) for preclinical applications using DOTA-Tyr 3 -octreotate (DOTATATE), a somatostatin analogue. The following labelling conditions of DOTATATE with 213 Bi were investigated; peptide mass was varied from 1.7 to 7.0 nmol, concentration of TRIS buffer from 0.15 mol.L -1 to 0.34 mol.L -1 , and ascorbic acid from 0 to 71 mmol.L -1 in 800 μL. All reactions were performed at 95 °C for 5 min. After incubation, DTPA (50 nmol) was added to stop the labelling reaction. Besides optimizing the labelling conditions, incorporation yield was determined by ITLC-SG and radiochemical purity (RCP) was monitored by RP-HPLC up to 120 min after labelling. Dosimetry studies in the reaction vial were performed using Monte Carlo and in vitro clonogenic assay was performed with a rat pancreatic tumour cell line, CA20948. At least 3.5 nmol DOTATATE was required to obtain incorporation ≥ 99 % with 100 MBq 213 Bi (at optimized pH conditions, pH 8.3 with 0.15 mol.L -1 TRIS) in a reaction volume of 800 μL. The cumulative absorbed dose in the reaction vial was 230 Gy/100 MBq in 30 min. A minimal final concentration of 0.9 mmol.L -1 ascorbic acid was required for ~100 MBq (t = 0) to minimize radiation damage of DOTATATE. The osmolarity was decreased to 0.45 Osmol/L.Under optimized labelling conditions, 213 Bi-DOTATATE remained stable up to 2 h after labelling, RCP was ≥ 85 %. In vitro showed a negative correlation between ascorbic acid

  5. Dose response and repair kinetics of gamma-H2AX foci induced by in vitro irradiation of whole blood and T-lymphocytes with X- and gamma-radiation.

    PubMed

    Beels, Laurence; Werbrouck, Joke; Thierens, Hubert

    2010-09-01

    Dose response and repair kinetics of phosphorylated histone H2A isoform X (gamma-H2AX) foci in T-lymphocytes were investigated in the low-dose range after in vitro irradiation of whole blood and T-lymphocytes with 100 kVp X-rays and (60)Co gamma-rays. Whole blood or isolated T-lymphocytes were irradiated in vitro and gamma-H2AX foci were scored. Dose response was determined in the 0-500 mGy dose range. Foci kinetics were studied at doses of 5 and 200 mGy up to 24 h post-irradiation. After X-irradiation, the dose response for whole blood shows a biphasic behaviour with a low-dose hypersensitivity, which is less pronounced for isolated T-lymphocytes. In contrast, gamma-radiation shows a linear dose response for both irradiation conditions. Concerning repair kinetics, delayed repair was found after X-ray whole blood irradiation (5 and 200 mGy) with 40% of the foci persisting 24 h post-irradiation. This number of foci is reduced to 10% after irradiation of isolated T-lymphocytes with 200 mGy X-rays. On the contrary, gamma-H2AX foci are reduced to background levels 24 h post-irradiation with 200 mGy (60)Co gamma-rays. gamma-H2AX foci response and repair kinetics depend on irradiation conditions and radiation quality, possibly linked to Bystander response.

  6. 41 CFR 101-6.213-7 - Post termination proceedings.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Post termination proceedings. 101-6.213-7 Section 101-6.213-7 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 6-MISCELLANEOUS REGULATIONS 6.2...

  7. 47 CFR 22.213 - Filing of long-form applications.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Filing of long-form applications. 22.213... PUBLIC MOBILE SERVICES Licensing Requirements and Procedures Competitive Bidding Procedures § 22.213 Filing of long-form applications. After an auction, the Commission will not accept long form applications...

  8. 41 CFR 101-6.213-6 - Content of orders.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 41 Public Contracts and Property Management 2 2011-07-01 2007-07-01 true Content of orders. 101-6.213-6 Section 101-6.213-6 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 6-MISCELLANEOUS REGULATIONS 6.2...

  9. Biodistributions, Myelosuppression, and Toxicities in Mice Treated with an Anti-CD45 Antibody Labeled with the alpha-Emitting Radionuclides Bismuth-213 or Astatine-211

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nakamae, Hirohisa; Wilbur, D. Scott; Hamlin, Donald K.

    2009-03-15

    We previously investigated 213Bi-labeled anti-CD45 antibody to replace total body irradiation as conditioning for hematopoietic cell transplantation in a canine model. While this allowed sustained engraftment of marrow, limited availability and high cost of 213Bi led to a preliminary investigation in mice of 211At-labeled antibody for the same application. To gain an understanding of the differences between the two radionuclides, biodistribution and myelosuppression/toxicity studies were conducted with 213Bi- and 211At-labeled rat anti-murine CD45 antibody, 30F11, conjugates. After injecting mice with 2-50 μCi on 10 μg 30F11 conjugate or 20 μCi on 2 or 40 μg conjugate, biodistributions, myelosuppression and non-hematologicalmore » toxicities were evaluated. Biodistribution studies showed that the spleen had the highest concentration of radioactivity, ranging from167-417 % injected dose/gram (%ID/g) at 24 h after injection in the 211At studies and 45-166 %ID/g at 3 h after injection in the 213Bi studies. The higher concentrations observed for 211At-labeled 30F11 was likely due to its longer half-life which, permitted more localization of antibody to the spleen before decay. 211At was more effective at myelosuppression for the same (mCi) quantity of injected radioactivity. Injection of only 20 or 50 μCi 211At resulted in lethal myeloablation. There was severe reversible acute hepatic toxicity with 50 μCi 213Bi, but not with lower doses or any dose of 211At. No significant renal toxicity occurred with either radionuclide. The data suggested that considerably lower quantities of 211At-labeled anti-CD45 antibody than 213Bi-labeled antibody might be effective for myelosuppression.« less

  10. Antimicrobial activity and mechanism of PDC213, an endogenous peptide from human milk

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sun, Yazhou; Nanjing Maternal and Child Health Medical Institute, Nanjing Maternal and Child Health Hospital, Obstetrics and Gynecology Hospital Affiliated to Nanjing Medical University, Nanjing; Zhou, Yahui

    Human milk has always been considered an ideal source of elemental nutrients to both preterm and full term infants in order to optimally develop the infant's tissues and organs. Recently, hundreds of endogenous milk peptides were identified in human milk. These peptides exhibited angiotensin-converting enzyme inhibition, immunomodulation, or antimicrobial activity. Here, we report the antimicrobial activity and mechanism of a novel type of human antimicrobial peptide (AMP), termed PDC213 (peptide derived from β-Casein 213-226 aa). PDC213 is an endogenous peptide and is present at higher levels in preterm milk than in full term milk. The inhibitory concentration curve and diskmore » diffusion tests showed that PDC213 had obvious antimicrobial against S. aureus and Y. enterocolitica, the common nosocomial pathogens in neonatal intensive care units (NICUs). Fluorescent dye methods, electron microscopy experiments and DNA-binding activity assays further indicated that PDC213 can permeabilize bacterial membranes and cell walls rather than bind intracellular DNA to kill bacteria. Together, our results suggest that PDC213 is a novel type of AMP that warrants further investigation. - Highlights: • PDC213 is an endogenous peptide presenting higher levels in preterm milk. • PDC213 showed obvious antimicrobial against S. aereus and Y. enterocolitica. • PDC213 can permeabilize bacterial membranes and cell walls to kill bacterias. • PDC213 is a novel type of antimicrobial peptides worthy further investigation.« less

  11. 19 CFR 213.1 - Purpose and applicability of part.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 213.1 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.1 Purpose and applicability of part. (a) Section 339 of the Tariff Act of 1930, as amended, establishes in the Commission an office known as the Trade Remedy...

  12. 19 CFR 213.1 - Purpose and applicability of part.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 213.1 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.1 Purpose and applicability of part. (a) Section 339 of the Tariff Act of 1930, as amended, establishes in the Commission an office known as the Trade Remedy...

  13. 19 CFR 213.1 - Purpose and applicability of part.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 213.1 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.1 Purpose and applicability of part. (a) Section 339 of the Tariff Act of 1930, as amended, establishes in the Commission an office known as the Trade Remedy...

  14. 19 CFR 213.1 - Purpose and applicability of part.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 213.1 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.1 Purpose and applicability of part. (a) Section 339 of the Tariff Act of 1930, as amended, establishes in the Commission an office known as the Trade Remedy...

  15. 26 CFR 1.213-1 - Medical, dental, etc., expenses.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 3 2012-04-01 2012-04-01 false Medical, dental, etc., expenses. 1.213-1 Section... (CONTINUED) INCOME TAXES (CONTINUED) Additional Itemized Deductions for Individuals § 1.213-1 Medical, dental... (including nurses' board where paid by the taxpayer), medical, laboratory, surgical, dental and other...

  16. 26 CFR 1.213-1 - Medical, dental, etc., expenses.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 3 2014-04-01 2014-04-01 false Medical, dental, etc., expenses. 1.213-1 Section... (CONTINUED) INCOME TAXES (CONTINUED) Additional Itemized Deductions for Individuals § 1.213-1 Medical, dental... (including nurses' board where paid by the taxpayer), medical, laboratory, surgical, dental and other...

  17. 26 CFR 1.213-1 - Medical, dental, etc., expenses.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 3 2013-04-01 2013-04-01 false Medical, dental, etc., expenses. 1.213-1 Section... (CONTINUED) INCOME TAXES (CONTINUED) Additional Itemized Deductions for Individuals § 1.213-1 Medical, dental... (including nurses' board where paid by the taxpayer), medical, laboratory, surgical, dental and other...

  18. 49 CFR 1544.213 - Use of explosives detection systems.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Use of explosives detection systems. 1544.213...: AIR CARRIERS AND COMMERCIAL OPERATORS Operations § 1544.213 Use of explosives detection systems. (a) Use of explosive detection equipment. If TSA so requires by an amendment to an aircraft operator's...

  19. 49 CFR 1544.213 - Use of explosives detection systems.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Use of explosives detection systems. 1544.213...: AIR CARRIERS AND COMMERCIAL OPERATORS Operations § 1544.213 Use of explosives detection systems. (a) Use of explosive detection equipment. If TSA so requires by an amendment to an aircraft operator's...

  20. 49 CFR 1544.213 - Use of explosives detection systems.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 9 2013-10-01 2013-10-01 false Use of explosives detection systems. 1544.213...: AIR CARRIERS AND COMMERCIAL OPERATORS Operations § 1544.213 Use of explosives detection systems. (a) Use of explosive detection equipment. If TSA so requires by an amendment to an aircraft operator's...

  1. 49 CFR 1544.213 - Use of explosives detection systems.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Use of explosives detection systems. 1544.213...: AIR CARRIERS AND COMMERCIAL OPERATORS Operations § 1544.213 Use of explosives detection systems. (a) Use of explosive detection equipment. If TSA so requires by an amendment to an aircraft operator's...

  2. 34 CFR 685.213 - Total and permanent disability discharge.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Total and permanent disability discharge. 685.213... § 685.213 Total and permanent disability discharge. (a) General. (1) A borrower's Direct Loan is... on a total and permanent disability, a borrower must submit a discharge application to the Secretary...

  3. 19 CFR 213.3 - Determination of small business eligibility.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 3 2012-04-01 2012-04-01 false Determination of small business eligibility. 213.3... PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.3 Determination of small business eligibility. (a) Application for technical assistance from small businesses. An applicant for technical assistance must certify...

  4. Hardly Rocket Science: Collaboration with Math and Science Teachers Doesn't Need to Be Complicated

    ERIC Educational Resources Information Center

    Minkel, Walter

    2004-01-01

    While librarians routinely collaborate with reading and humanities teachers, they rarely partner with teachers of math and science--to the loss of students. With the current emphasis on standardized testing and declining student performance in math and science, media specialists need to remedy this situation. Why don't librarians click with…

  5. Irradiated HMEC from A-T Heterozygous Breast Tissue

    NASA Technical Reports Server (NTRS)

    Richmond, Robert; Bors, Karen; Cruz, Angela; Pettengil, Olive; Curreri, Peter A. (Technical Monitor)

    2002-01-01

    Women who are heterozygous for ataxia-telangiectasia (A-T) carry a single defective ATM gene in chromosome 11 q22-23, and have been statistically determined with high significance within a defined database to be approximately 5-fold more susceptible for developing breast cancer than their noma1 counterpart. Breast cancer susceptibility of these A-T heterozygotes has been hypothesized to include consequence of response to damage caused by low levels of ionizing radiation. Prophylactic mastectomy specimens were donated by a 41 year-old obligate A-T heterozygote who was located prior to her elective surgery through an existing pedigree. Harvest of that breast tissue provided an isolate of long-term growth human mammary epithelial cells (HMEC), designated WH612/3. An isolate of presumed normal long-term growth HMEC, designated 48R, was obtained from Dr. Martha Stampfer (Lawrence Berkeley Laboratory, University of California), and the A-T heterozygous HMEC were transformed with E6 and E7 oncogenes of human papilloma virus Type-16 in the laboratory of Dr. Ray White (Hunt- Cancer Institute, University of Utah) for use in this study. The objective of this study is to study the expression of end points that may bear on cancer outcome following irradiation of HMEC. Specific end points are cell survival, cell cycle, p53 expression, and apoptosis. Survival curves, immunostaining, and flow cytometery are used to examine these end points. Radiation-induced cell killing shows less shoulder development in the survival curve for WH61U3 compared to 48R HMEC, suggesting less repair of damage in the former HMEC. Additional information is included in the original extended abstract.

  6. Evaluation of the Delta-T SPN1 radiometer for the measurement of solar irradiance components

    NASA Astrophysics Data System (ADS)

    Estelles, Victor; Serrano, David; Segura, Sara; Wood, John; Webb, Nick; Utrillas, Maria Pilar

    2016-04-01

    In this study we analyse the performance of an SPN1 radiometer built by Delta-T Devices Ltd. to retrieve global solar irradiance at ground and its components (diffuse, direct) in comparison with measurements from two Kipp&Zonen CMP21 radiometers and a Kipp&Zonen CHP1 pirheliometer, mounted on an active Solys-2 suntracker at the Burjassot site (Valencia, Spain) using data acquired every minute during years 2013 - 2015. The measurement site is close to sea level (60 m a.s.l.), near the Mediterranean coast (10 km) and within the metropolitan area of Valencia City (over 1.500.000 inhabitants). The SPN1 is an inexpensive and versatile instrument for the measurement of the three components of the solar radiation without any mobile part and without any need to azimuthally align the instrument to track the sun (http://www.delta-t.co.uk). The three components of the solar radiation are estimated from a combination of measurements performed by 7 different miniature thermopiles. The SPN1 pyranometer measures the irradiance between 400 and 2700 nm, and the nominal uncertainty for the individual readings is about 8% ± 10 W/m2 (5% for the daily averages). The pyranometer Kipp&Zonen CMP21 model is a secondary standard for the measurement of broadband solar global irradiance in horizontal planes. Two ventilated CMP21 are used for the measurement of the global and diffuse irradiances. The expected total daily uncertainty of the radiometer is estimated to be 2%. The pirheliometer Kipp&Zonen CHP1 is designed for the measurement of the direct irradiance. The principles are similar to the CMP21 pyranometer. The results of the comparison show that the global irradiance from the SPN1 compares very well with the CMP21, with absolute RMSD and MBD differences below the combined uncertainties (15 W/m2 and -5.4 W/m2, respectively; relative RMSD of 3.1%). Both datasets are very well correlated, with a correlation coefficient higher than 0.997 and a slope and intercept very close to 1 and 0

  7. RORγt antagonist suppresses M3 muscarinic acetylcholine receptor-induced Sjögren's syndrome-like sialadenitis.

    PubMed

    Tahara, M; Tsuboi, H; Segawa, S; Asashima, H; Iizuka-Koga, M; Hirota, T; Takahashi, H; Kondo, Y; Matsui, M; Matsumoto, I; Sumida, T

    2017-02-01

    We showed recently that M3 muscarinic acetylcholine receptor (M3R)-reactive CD3 + T cells play a pathogenic role in the development of murine autoimmune sialadenitis (MIS), which mimics Sjögren's syndrome (SS). The aim of this study was to determine the effectiveness and mechanism of action of retinoic acid-related orphan receptor-gamma t (RORγt) antagonist (A213) in MIS. Splenocytes from M3R knockout (M3R -/- ) mice immunized with murine M3R peptide mixture were inoculated into recombination-activating gene 1 knockout (Rag-1 -/- ) mice (M3R -/- →Rag-1 -/- ) with MIS. Immunized M3R -/- mice (pretransfer treatment) and M3R -/- →Rag-1 -/- mice (post-transfer treatment) were treated with A213 every 3 days. Salivary volume, severity of sialadenitis and cytokine production from M3R peptide-stimulated splenocytes and lymph node cells were examined. Effects of A213 on cytokine production were analysed by enzyme-linked immunosorbent assay (ELISA) and on T helper type 1 (Th1), Th17 and Th2 differentiation from CD4 + T cells by flow cytometry. Pretransfer A213 treatment maintained salivary volume, improved MIS and reduced interferon (IFN)-γ and interleukin (IL)-17 production significantly compared with phosphate-buffered saline (PBS) (P < 0·05). These suppressive effects involved CD4 + T cells rather than CD11c + cells. Post-transfer treatment with A213 increased salivary volume (P < 0·05), suppressed MIS (P < 0·005) and reduced IFN-γ and IL-17 production (P < 0·05). In vitro, A213 suppressed IFN-γ and IL-17 production from M3R-stimulated splenocytes and CD4 + T cells of immunized M3R -/- mice (P < 0·05). In contrast with M3R specific responses, A213 suppressed only IL-17 production from Th17 differentiated CD4 + T cells without any effect on Th1 and Th2 differentiation in vitro. Our findings suggested that RORγt antagonism is potentially suitable treatment strategy for SS-like sialadenitis through suppression of IL-17 and IFN-γ production

  8. 24 CFR 213.260 - Allowable methods of premium payment.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Allowable methods of premium payment. 213.260 Section 213.260 Housing and Urban Development Regulations Relating to Housing and Urban... Allowable methods of premium payment. Premiums shall be payable in cash or in debentures at par plus accrued...

  9. 24 CFR 213.260 - Allowable methods of premium payment.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Allowable methods of premium payment. 213.260 Section 213.260 Housing and Urban Development Regulations Relating to Housing and Urban... Allowable methods of premium payment. Premiums shall be payable in cash or in debentures at par plus accrued...

  10. 24 CFR 213.260 - Allowable methods of premium payment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Allowable methods of premium payment. 213.260 Section 213.260 Housing and Urban Development Regulations Relating to Housing and Urban... Allowable methods of premium payment. Premiums shall be payable in cash or in debentures at par plus accrued...

  11. 24 CFR 213.260 - Allowable methods of premium payment.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Allowable methods of premium payment. 213.260 Section 213.260 Housing and Urban Development Regulations Relating to Housing and Urban... Allowable methods of premium payment. Premiums shall be payable in cash or in debentures at par plus accrued...

  12. 24 CFR 213.260 - Allowable methods of premium payment.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Allowable methods of premium payment. 213.260 Section 213.260 Housing and Urban Development Regulations Relating to Housing and Urban... Allowable methods of premium payment. Premiums shall be payable in cash or in debentures at par plus accrued...

  13. 41 CFR 101-6.213-6 - Content of orders.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 41 Public Contracts and Property Management 2 2014-07-01 2012-07-01 true Content of orders. 101-6.213-6 Section 101-6.213-6 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 6-MISCELLANEOUS REGULATIONS 6.2-Nondiscrimination in Programs Receiving Federal...

  14. 47 CFR 97.213 - Telecommand of an amateur station.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... telephone number of the station licensee and at least one designated control operator is posted in a... 47 Telecommunication 5 2011-10-01 2011-10-01 false Telecommand of an amateur station. 97.213... SERVICES AMATEUR RADIO SERVICE Special Operations § 97.213 Telecommand of an amateur station. An amateur...

  15. 47 CFR 97.213 - Telecommand of an amateur station.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... telephone number of the station licensee and at least one designated control operator is posted in a... 47 Telecommunication 5 2010-10-01 2010-10-01 false Telecommand of an amateur station. 97.213... SERVICES AMATEUR RADIO SERVICE Special Operations § 97.213 Telecommand of an amateur station. An amateur...

  16. 47 CFR 97.213 - Telecommand of an amateur station.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... telephone number of the station licensee and at least one designated control operator is posted in a... 47 Telecommunication 5 2014-10-01 2014-10-01 false Telecommand of an amateur station. 97.213... SERVICES AMATEUR RADIO SERVICE Special Operations § 97.213 Telecommand of an amateur station. An amateur...

  17. 47 CFR 97.213 - Telecommand of an amateur station.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... telephone number of the station licensee and at least one designated control operator is posted in a... 47 Telecommunication 5 2013-10-01 2013-10-01 false Telecommand of an amateur station. 97.213... SERVICES AMATEUR RADIO SERVICE Special Operations § 97.213 Telecommand of an amateur station. An amateur...

  18. 47 CFR 97.213 - Telecommand of an amateur station.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... telephone number of the station licensee and at least one designated control operator is posted in a... 47 Telecommunication 5 2012-10-01 2012-10-01 false Telecommand of an amateur station. 97.213... SERVICES AMATEUR RADIO SERVICE Special Operations § 97.213 Telecommand of an amateur station. An amateur...

  19. 49 CFR 213.329 - Curves, elevation and speed limitations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Curves, elevation and speed limitations. 213.329... Higher § 213.329 Curves, elevation and speed limitations. (a) The maximum crosslevel on the outside rail... lower than the inside rail. (b) (1) The maximum allowable operating speed for each curve is determined...

  20. 49 CFR 213.329 - Curves, elevation and speed limitations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Curves, elevation and speed limitations. 213.329... Higher § 213.329 Curves, elevation and speed limitations. (a) The maximum crosslevel on the outside rail... lower than the inside rail. (b) (1) The maximum allowable operating speed for each curve is determined...

  1. RNF213 Rare Variants in Slovakian and Czech Moyamoya Disease Patients.

    PubMed

    Kobayashi, Hatasu; Brozman, Miroslav; Kyselová, Kateřina; Viszlayová, Daša; Morimoto, Takaaki; Roubec, Martin; Školoudík, David; Petrovičová, Andrea; Juskanič, Dominik; Strauss, Jozef; Halaj, Marián; Kurray, Peter; Hranai, Marián; Harada, Kouji H; Inoue, Sumiko; Yoshida, Yukako; Habu, Toshiyuki; Herzig, Roman; Youssefian, Shohab; Koizumi, Akio

    2016-01-01

    RNF213/Mysterin has been identified as a susceptibility gene for moyamoya disease, a cerebrovascular disease characterized by occlusive lesions in the circle of Willis. The p.R4810K (rs112735431) variant is a founder polymorphism that is strongly associated with moyamoya disease in East Asia. Many non-p.R4810K rare variants of RNF213 have been identified in white moyamoya disease patients, although the ethnic mutations have not been investigated in this population. In the present study, we screened for RNF213 variants in 19 Slovakian and Czech moyamoya disease patients. A total of 69 RNF213 coding exons were directly sequenced in 18 probands and one relative who suffered from moyamoya disease in Slovakia and the Czech Republic. We previously reported one proband harboring RNF213 p.D4013N. Results from the present study identified four rare variants other than p.D4013N (p.R4019C, p.E4042K, p.V4146A, and p.W4677L) in four of the patients. P.V4146A was determined to be a novel de novo mutation, and p.R4019C and p.E4042K were identified as double mutations inherited on the same allele. P.W4677L, found in two moyamoya disease patients and an unaffected subject in the same pedigree, was a rare single nucleotide polymorphism. Functional analysis showed that RNF213 p.D4013N, p.R4019C and p.V4146A-transfected human umbilical vein endothelial cells displayed significant lowered migration, and RNF213 p.V4146A significantly reduced tube formation, indicating that these are disease-causing mutations. Results from the present study identified RNF213 rare variants in 22.2% (4/18 probands) of Slovakian and Czech moyamoya disease patients, confirming that RNF213 may also be a major causative gene in a relative large population of white patients.

  2. RNF213 Rare Variants in Slovakian and Czech Moyamoya Disease Patients

    PubMed Central

    Kyselová, Kateřina; Viszlayová, Daša; Morimoto, Takaaki; Roubec, Martin; Školoudík, David; Petrovičová, Andrea; Juskanič, Dominik; Strauss, Jozef; Halaj, Marián; Kurray, Peter; Hranai, Marián; Harada, Kouji H.; Inoue, Sumiko; Yoshida, Yukako; Habu, Toshiyuki; Herzig, Roman; Youssefian, Shohab; Koizumi, Akio

    2016-01-01

    RNF213/Mysterin has been identified as a susceptibility gene for moyamoya disease, a cerebrovascular disease characterized by occlusive lesions in the circle of Willis. The p.R4810K (rs112735431) variant is a founder polymorphism that is strongly associated with moyamoya disease in East Asia. Many non-p.R4810K rare variants of RNF213 have been identified in white moyamoya disease patients, although the ethnic mutations have not been investigated in this population. In the present study, we screened for RNF213 variants in 19 Slovakian and Czech moyamoya disease patients. A total of 69 RNF213 coding exons were directly sequenced in 18 probands and one relative who suffered from moyamoya disease in Slovakia and the Czech Republic. We previously reported one proband harboring RNF213 p.D4013N. Results from the present study identified four rare variants other than p.D4013N (p.R4019C, p.E4042K, p.V4146A, and p.W4677L) in four of the patients. P.V4146A was determined to be a novel de novo mutation, and p.R4019C and p.E4042K were identified as double mutations inherited on the same allele. P.W4677L, found in two moyamoya disease patients and an unaffected subject in the same pedigree, was a rare single nucleotide polymorphism. Functional analysis showed that RNF213 p.D4013N, p.R4019C and p.V4146A-transfected human umbilical vein endothelial cells displayed significant lowered migration, and RNF213 p.V4146A significantly reduced tube formation, indicating that these are disease-causing mutations. Results from the present study identified RNF213 rare variants in 22.2% (4/18 probands) of Slovakian and Czech moyamoya disease patients, confirming that RNF213 may also be a major causative gene in a relative large population of white patients. PMID:27736983

  3. 36 CFR 213.3 - Protection, occupancy, use, administration, and exercise of reservations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., administration, and exercise of reservations. 213.3 Section 213.3 Parks, Forests, and Public Property FOREST... TENANT ACT BY THE FOREST SERVICE § 213.3 Protection, occupancy, use, administration, and exercise of... the rules and regulations to govern the exercise of reservations in conveyances to the United States...

  4. 36 CFR 213.3 - Protection, occupancy, use, administration, and exercise of reservations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., administration, and exercise of reservations. 213.3 Section 213.3 Parks, Forests, and Public Property FOREST... TENANT ACT BY THE FOREST SERVICE § 213.3 Protection, occupancy, use, administration, and exercise of... the rules and regulations to govern the exercise of reservations in conveyances to the United States...

  5. 36 CFR 213.3 - Protection, occupancy, use, administration, and exercise of reservations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., administration, and exercise of reservations. 213.3 Section 213.3 Parks, Forests, and Public Property FOREST... TENANT ACT BY THE FOREST SERVICE § 213.3 Protection, occupancy, use, administration, and exercise of... the rules and regulations to govern the exercise of reservations in conveyances to the United States...

  6. 36 CFR 213.3 - Protection, occupancy, use, administration, and exercise of reservations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., administration, and exercise of reservations. 213.3 Section 213.3 Parks, Forests, and Public Property FOREST... TENANT ACT BY THE FOREST SERVICE § 213.3 Protection, occupancy, use, administration, and exercise of... the rules and regulations to govern the exercise of reservations in conveyances to the United States...

  7. 36 CFR 213.3 - Protection, occupancy, use, administration, and exercise of reservations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., administration, and exercise of reservations. 213.3 Section 213.3 Parks, Forests, and Public Property FOREST... TENANT ACT BY THE FOREST SERVICE § 213.3 Protection, occupancy, use, administration, and exercise of... the rules and regulations to govern the exercise of reservations in conveyances to the United States...

  8. 22 CFR 213.22 - Salary offset when USAID is the creditor agency.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Salary offset when USAID is the creditor agency. 213.22 Section 213.22 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT CLAIMS COLLECTION Administrative Offset § 213.22 Salary offset when USAID is the creditor agency. (a) Due process requirements...

  9. 22 CFR 213.22 - Salary offset when USAID is the creditor agency.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Salary offset when USAID is the creditor agency. 213.22 Section 213.22 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT CLAIMS COLLECTION Administrative Offset § 213.22 Salary offset when USAID is the creditor agency. (a) Due process requirements...

  10. 22 CFR 213.22 - Salary offset when USAID is the creditor agency.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Salary offset when USAID is the creditor agency. 213.22 Section 213.22 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT CLAIMS COLLECTION Administrative Offset § 213.22 Salary offset when USAID is the creditor agency. (a) Due process requirements...

  11. 22 CFR 213.22 - Salary offset when USAID is the creditor agency.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Salary offset when USAID is the creditor agency. 213.22 Section 213.22 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT CLAIMS COLLECTION Administrative Offset § 213.22 Salary offset when USAID is the creditor agency. (a) Due process requirements...

  12. 3. Oblique view of 213 Division Street, looking northeast, showing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Oblique view of 213 Division Street, looking northeast, showing rear (west) facade and south side, 215 Division Street is visible at left and Fairbanks Company appears at right - 213 Division Street (House), Rome, Floyd County, GA

  13. 25 CFR 39.213 - Will the Bureau fund children being home schooled?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Will the Bureau fund children being home schooled? 39.213 Section 39.213 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION THE INDIAN SCHOOL EQUALIZATION PROGRAM Administrative Procedures, Student Counts, and Verifications § 39.213 Will the Bureau fund...

  14. Collaboration in the competitive world of science: lessons to be learned from William T. Keeton.

    PubMed

    Zupanc, Günther K H

    2015-10-01

    The tremendous increase in the number of authors and institutional affiliations on papers published in the natural sciences over the last few decades is commonly interpreted as an indicator of an increase in the collaborative spirit. However, a closer analysis suggests that this development reflects an increase in cooperation (defined as a strategy to divide labor among participants), rather than a rise in collaboration (defined as a mutual engagement of participants in a coordinated effort to jointly solve a problem). An exception to this development was William T. Keeton (1933-1980), who, as a faculty member at Cornell University, pioneered research into pigeon homing. A direct result of his willingness to openly share ideas and collaborate with other investigators is the article by Hagstrum and Manley (J Comp Physiol A, 2015) in this issue of the Journal of Comparative Physiology A. Their study is based on data from experiments Keeton and his collaborators conducted some 40 years ago. Despite the age of these data, their analysis and the interpretation of the results are likely to stimulate fruitful discussion in the field of avian orientation.

  15. 45 CFR 213.3 - Use of gender and number.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 2 2012-10-01 2012-10-01 false Use of gender and number. 213.3 Section 213.3... gender and number. As used in this part, words importing the singular number may extend and be applied to several persons or things, and vice versa. Words importing the masculine gender may be applied to females...

  16. 45 CFR 213.3 - Use of gender and number.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 2 2014-10-01 2012-10-01 true Use of gender and number. 213.3 Section 213.3... gender and number. As used in this part, words importing the singular number may extend and be applied to several persons or things, and vice versa. Words importing the masculine gender may be applied to females...

  17. 45 CFR 213.3 - Use of gender and number.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 2 2011-10-01 2011-10-01 false Use of gender and number. 213.3 Section 213.3... gender and number. As used in this part, words importing the singular number may extend and be applied to several persons or things, and vice versa. Words importing the masculine gender may be applied to females...

  18. 45 CFR 213.3 - Use of gender and number.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true Use of gender and number. 213.3 Section 213.3... gender and number. As used in this part, words importing the singular number may extend and be applied to several persons or things, and vice versa. Words importing the masculine gender may be applied to females...

  19. 45 CFR 213.3 - Use of gender and number.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Use of gender and number. 213.3 Section 213.3... gender and number. As used in this part, words importing the singular number may extend and be applied to several persons or things, and vice versa. Words importing the masculine gender may be applied to females...

  20. 45 CFR 213.5 - Filing and service of papers.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 2 2011-10-01 2011-10-01 false Filing and service of papers. 213.5 Section 213.5... and service of papers. (a) All papers in the proceedings shall be filed with the FSA Hearing Clerk, in...) All papers in the proceedings shall be served on all parties by personal delivery or by mail. Service...

  1. 45 CFR 213.5 - Filing and service of papers.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Filing and service of papers. 213.5 Section 213.5... and service of papers. (a) All papers in the proceedings shall be filed with the FSA Hearing Clerk, in...) All papers in the proceedings shall be served on all parties by personal delivery or by mail. Service...

  2. 19 CFR 213.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.2 Definitions. (a) Office. The Trade Remedy Assistance Office (hereinafter Office... Trade Remedy Assistance Office, U.S. International Trade Commission, 500 E Street SW., Washington, DC...

  3. 19 CFR 213.2 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.2 Definitions. (a) Office. The Trade Remedy Assistance Office (hereinafter Office... Trade Remedy Assistance Office, U.S. International Trade Commission, 500 E Street SW., Washington, DC...

  4. 19 CFR 213.2 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.2 Definitions. (a) Office. The Trade Remedy Assistance Office (hereinafter Office... Trade Remedy Assistance Office, U.S. International Trade Commission, 500 E Street SW., Washington, DC...

  5. 19 CFR 213.2 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.2 Definitions. (a) Office. The Trade Remedy Assistance Office (hereinafter Office... Trade Remedy Assistance Office, U.S. International Trade Commission, 500 E Street SW., Washington, DC...

  6. Status of ADRIANO R&D in T1015 Collaboration

    DOE PAGES

    Gatto, Corrado; Di Benedetto, V.; Mazzacane, A.

    2015-02-13

    The physics program for future High Energy and High Intensity experiments requires an energy resolution of the calorimetric component of detectors at limits of traditional techniques and an excellent particle identification. The novel ADRIANO technology (A Dualreadout Integrally Active Non-segmented Option), currently under development at Fermilab, is showing excellent performance on those respects. Results from detailed Monte Carlo studies on the performance with respect to energy resolution, linear response and transverse containment and a preliminary optimization of the layout are presented. A baseline configuration is chosen with an estimated energy resolution of σ(E)/E ≈ 30%/√E , to support an extensivemore » R&D program recently started by T1015 Collaboration at Fermilab. Furthermore, preliminary results from several test beams at the Fermilab Test Beam Facility (FTBF) of a ~ 1λI prototype are presented. Future prospects with ultra-heavy glass are, also, summarized.« less

  7. 50 CFR 660.213 - Fixed gear fishery-recordkeeping and reporting.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 11 2011-10-01 2011-10-01 false Fixed gear fishery-recordkeeping and reporting. 660.213 Section 660.213 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE (CONTINUED) FISHERIES OFF WEST COAST STATES...

  8. 50 CFR 660.213 - Fixed gear fishery-recordkeeping and reporting.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Fixed gear fishery-recordkeeping and reporting. 660.213 Section 660.213 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE (CONTINUED) FISHERIES OFF WEST COAST STATES...

  9. 19 CFR 213.4 - Disclosure of receipt of technical assistance.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ....4 Section 213.4 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.4 Disclosure of receipt of technical assistance. An... received technical assistance from the Trade Remedy Assistance Office in any resulting petition, complaint...

  10. 19 CFR 213.4 - Disclosure of receipt of technical assistance.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ....4 Section 213.4 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.4 Disclosure of receipt of technical assistance. An... received technical assistance from the Trade Remedy Assistance Office in any resulting petition, complaint...

  11. 19 CFR 213.4 - Disclosure of receipt of technical assistance.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ....4 Section 213.4 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.4 Disclosure of receipt of technical assistance. An... received technical assistance from the Trade Remedy Assistance Office in any resulting petition, complaint...

  12. 19 CFR 213.4 - Disclosure of receipt of technical assistance.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ....4 Section 213.4 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.4 Disclosure of receipt of technical assistance. An... received technical assistance from the Trade Remedy Assistance Office in any resulting petition, complaint...

  13. 7 CFR 1450.213 - Levels and rates for establishment payments.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Levels and rates for establishment payments. 1450.213 Section 1450.213 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM...

  14. 7 CFR 1450.213 - Levels and rates for establishment payments.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Levels and rates for establishment payments. 1450.213 Section 1450.213 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM...

  15. Quantum-state-selective decay spectroscopy of 213Ra

    NASA Astrophysics Data System (ADS)

    Lorenz, Ch.; Sarmiento, L. G.; Rudolph, D.; Ward, D. E.; Block, M.; Heßberger, F. P.; Ackermann, D.; Andersson, L.-L.; Cortés, M. L.; Droese, C.; Dworschak, M.; Eibach, M.; Forsberg, U.; Golubev, P.; Hoischen, R.; Kojouharov, I.; Khuyagbaatar, J.; Nesterenko, D.; Ragnarsson, I.; Schaffner, H.; Schweikhard, L.; Stolze, S.; Wenzl, J.

    2017-09-01

    An experimental scheme combining the mass resolving power of a Penning trap with contemporary decay spectroscopy has been established at GSI Darmstadt. The Universal Linear Accelerator (UNILAC) at GSI Darmstadt provided a 48Ca beam impinging on a thin 170Er target foil. Subsequent to velocity filtering of reaction products in the Separator for Heavy Ion reaction Products (SHIP), the nuclear ground state of the 5 n evaporation channel 213Ra was mass-selected in SHIPTRAP, and the 213Ra ions were finally transferred into an array of silicon strip detectors surrounded by large composite germanium detectors. Based on comprehensive geant4 simulations and supported by theoretical calculations, the spectroscopic results call for a revision of the decay path of 213Ra, thereby exemplifying the potential of a combination of a mass-selective Penning trap device with a dedicated nuclear decay station and contemporary geant4 simulations.

  16. 49 CFR 213.367 - Special inspections.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., DEPARTMENT OF TRANSPORTATION TRACK SAFETY STANDARDS Train Operations at Track Classes 6 and Higher § 213.367 Special inspections. In the event of fire, flood, severe storm, temperature extremes or other occurrence...

  17. 49 CFR 213.351 - Rail joints.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., DEPARTMENT OF TRANSPORTATION TRACK SAFETY STANDARDS Train Operations at Track Classes 6 and Higher § 213.351... contraction due to temperature variations. When no-slip, joint-to-rail contact exists by design, the...

  18. Ionizing radiation and autoimmunity: Induction of autoimmune disease in mice by high dose fractionated total lymphoid irradiation and its prevention by inoculating normal T cells

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sakaguchi, N.; Sakaguchi, S.; Miyai, K.

    1992-11-01

    Ionizing radiation can functionally alter the immune system and break self-tolerance. High dose (42.5 Gy), fractionated (2.5 Gy 17 times) total lymphoid irradiation (TLI) on mice caused various organ-specific autoimmune diseases, such as gastritis, thyroiditis, and orchitis, depending on the radiation dosages, the extent of lymphoid irradiation, and the genetic background of the mouse strains. Radiation-induced tissue damage is not the primary cause of the autoimmune disease because irradiation of the target organs alone failed to elicit the autoimmunity and shielding of the organs from irradiation was unable to prevent it. In contrast, irradiation of both the thymus and themore » peripheral lymphoid organs/tissues was required for efficient induction of autoimmune disease by TLI. TLI eliminated the majority of mature thymocytes and the peripheral T cells for 1 mo, and inoculation of spleen cell, thymocyte, or bone marrow cell suspensions (prepared from syngeneic nonirradiated mice) within 2 wk after TLI effectively prevented the autoimmune development. Depletion of T cells from the inocula abrogated the preventive activity. CD4[sup +] T cells mediated the autoimmune prevention but CD8[sup +] T cells did not. CD4[sup +] T cells also appeared to mediate the TLI-induced autoimmune disease because CD4[sup +] T cells from disease-bearing TLI mice adoptively transferred the autoimmune disease to syngeneic naive mice. Taken together, these results indicate that high dose, fractionated ionizing radiation on the lymphoid organs/tissues can cause autoimmune disease by affecting the T cell immune system, rather than the target self-Ags, presumably by altering T cell-dependent control of self-reactive T cells. 62 refs., 9 figs., 2 tabs.« less

  19. 42 CFR 405.213 - Re-evaluation of a device categorization.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 2 2011-10-01 2011-10-01 false Re-evaluation of a device categorization. 405.213... Decisions That Relate to Health Care Technology § 405.213 Re-evaluation of a device categorization. (a... experimental/investigational (Category A) may request re-evaluation of the categorization decision. (2) A...

  20. 42 CFR 405.213 - Re-evaluation of a device categorization.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Re-evaluation of a device categorization. 405.213... Decisions That Relate to Health Care Technology § 405.213 Re-evaluation of a device categorization. (a... experimental/investigational (Category A) may request re-evaluation of the categorization decision. (2) A...

  1. ACHP | ACHP Receives Section 213 Report on Presidio of San Francisco

    Science.gov Websites

    Search skip specific nav links Home arrow News arrow ACHP Receives Section 213 Report on Presidio of San Francisco ACHP Receives Section 213 Report on Presidio of San Francisco The ACHP received its requested

  2. Method And Apparatus For Production Of Bi-213 From The Activity Ac-225 Source

    DOEpatents

    Egorov, Oleg B.; O'Hara, Matthew J.

    2005-12-06

    A method and apparatus for isolating and purifying a .sup.213 Bi radioactive isotope from an .sup.225 Ac source using a primary column and a primary sorbent which preferentially retains .sup.225 Ac over .sup.213 Bi when exposed to a compatible solvent in combination with a secondary column having a secondary sorbent which retains .sup.213 Bi when exposed to a mixture of the compatible solvent and .sup.213 Bi. A "compatible solvent" is a solvent which will preferentially remove .sup.213 Bi radioactive isotopes from a primary sorbent without removing .sup.225 Ac radioactive isotopes, and then allow .sup.213 Bi radioactive isotopes removed from the primary sorbent to be retained on a secondary sorbent, without having to dilute or otherwise chemically or physically modify the compatible solvent in between exposure to the primary and secondary sorbents.

  3. Thermal property change of MOX and UO2 irradiated up to high burnup of 74 GWd/t

    NASA Astrophysics Data System (ADS)

    Nakae, Nobuo; Akiyama, Hidetoshi; Miura, Hiromichi; Baba, Toshikazu; Kamimura, Katsuichiro; Kurematsu, Shigeru; Kosaka, Yuji; Yoshino, Aya; Kitagawa, Takaaki

    2013-09-01

    Thermal property is important because it controls fuel behavior under irradiation. The thermal property change at high burnup of more than 70 GWd/t is examined. Two kinds of MOX fuel rods, which were fabricated by MIMAS and SBR methods, and one referenced UO2 fuel rod were used in the experiment. These rods were taken from the pre-irradiated rods (IFA 609/626, of which irradiation test were carried out by Japanese PWR group) and re-fabricated and re-irradiated in HBWR as IFA 702 by JNES. The specification of fuel corresponds to that of 17 × 17 PWR type fuel and the axially averaged linear heat rates (LHR) of MOX rods are 25 kW/m (BOL of IFA 702) and 20 kW/m (EOL of IFA 702). The axial peak burnups achieved are about 74 GWd/t for both of MOX and UO2. Centerline temperature and plenum gas pressure were measured in situ during irradiation. The measured centerline temperature is plotted against LHR at the position where thermocouples are fixed. The slopes of MOX are corresponded to each other, but that of UO2 is higher than those of MOX. This implies that the thermal conductivity of MOX is higher than that of UO2 at high burnup under the condition that the pellet-cladding gap is closed during irradiation. Gap closure is confirmed by the metallography of the postirradiation examinations. It is understood that thermal conductivity of MOX is lower than that of UO2 before irradiation since phonon scattering with plutonium in MOX becomes remarkable. A phonon scattering with plutonium decreases in MOX when burnup proceeds. Thus, thermal conductivity of MOX becomes close to that of UO2. A reverse phenomenon is observed at high burnup region. The phonon scattering with fission products such as Nd and Zr causes a degradation of thermal conductivity of burnt fuel. It might be speculated that this scattering effect causes the phenomenon and the mechanism is discussed here.

  4. 25 CFR 213.40 - Cancellations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... FIVE CIVILIZED TRIBES, OKLAHOMA, FOR MINING Operations § 213.40 Cancellations. (a) When, in the opinion... or of the applicable regulations, or if mining operations are conducted wastefully and without regard to good mining practice, the Secretary of the Interior shall have the right at any time after 30 days...

  5. 32 CFR 213.5 - Responsibilities.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... SUPPORT FOR NON-FEDERAL ENTITIES AUTHORIZED TO OPERATE ON DOD INSTALLATIONS § 213.5 Responsibilities. (a... policy matters and Office of the Secretary of Defense oversight of non-Federal entities on DoD... of non-Federal entities on DoD installations. (3) Assign responsibilities to the DoD Components to...

  6. 32 CFR 213.5 - Responsibilities.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... SUPPORT FOR NON-FEDERAL ENTITIES AUTHORIZED TO OPERATE ON DOD INSTALLATIONS § 213.5 Responsibilities. (a... policy matters and Office of the Secretary of Defense oversight of non-Federal entities on DoD... of non-Federal entities on DoD installations. (3) Assign responsibilities to the DoD Components to...

  7. 32 CFR 213.5 - Responsibilities.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... SUPPORT FOR NON-FEDERAL ENTITIES AUTHORIZED TO OPERATE ON DOD INSTALLATIONS § 213.5 Responsibilities. (a... policy matters and Office of the Secretary of Defense oversight of non-Federal entities on DoD... of non-Federal entities on DoD installations. (3) Assign responsibilities to the DoD Components to...

  8. 32 CFR 213.5 - Responsibilities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... SUPPORT FOR NON-FEDERAL ENTITIES AUTHORIZED TO OPERATE ON DOD INSTALLATIONS § 213.5 Responsibilities. (a... policy matters and Office of the Secretary of Defense oversight of non-Federal entities on DoD... of non-Federal entities on DoD installations. (3) Assign responsibilities to the DoD Components to...

  9. 32 CFR 213.5 - Responsibilities.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... SUPPORT FOR NON-FEDERAL ENTITIES AUTHORIZED TO OPERATE ON DOD INSTALLATIONS § 213.5 Responsibilities. (a... policy matters and Office of the Secretary of Defense oversight of non-Federal entities on DoD... of non-Federal entities on DoD installations. (3) Assign responsibilities to the DoD Components to...

  10. The Teamwork Mini-Clinical Evaluation Exercise (T-MEX): a workplace-based assessment focusing on collaborative competencies in health care.

    PubMed

    Olupeliyawa, Asela M; O'Sullivan, Anthony J; Hughes, Chris; Balasooriya, Chinthaka D

    2014-02-01

    Teamwork is an important and challenging area of learning during the transition from medical graduate to intern. This preliminary investigation examined the psychometric and logistic properties of the Teamwork Mini-Clinical Evaluation Exercise (T-MEX) for the workplace-based assessment of key competencies in working with health care teams. The authors designed the T-MEX for direct observation and assessment of six collaborative behaviors in seven clinical situations important for teamwork, feedback, and reflection. In 2010, they tested it on University of New South Wales senior medical students during their last six-week clinical term to investigate its overall utility, including validity and reliability. Assessors rated students in different situations on the extent to which they met expectations for interns for each collaborative behavior. Both assessors and students rated the tool's usefulness and feasibility. Assessment forms for 88 observed encounters were submitted by 25 students. The T-MEX was suited to a broad range of collaborative clinical practice situations, as evidenced by the encounter types and the behaviors assessed by health care team members. The internal structure of the behavior ratings indicated construct validity. A generalizability study found that eight encounters were adequate for high-stakes measurement purposes. The mean times for observation and feedback and the participants' perceptions suggested usefulness for feedback and feasibility in busy clinical settings. Findings suggest that the T-MEX has good utility for assessing trainee competence in working with health care teams. It fills a gap within the suite of existing tools for workplace-based assessment of professional attributes.

  11. Persistent T2*-hypointensity of the liver parenchyma after irradiation to the SPIO-accumulated liver: An imaging marker for responses to radiotherapy in hepatic malignancies.

    PubMed

    Furuta, Toshihiro; Yamaguchi, Masayuki; Minami, Manabu; Ohtomo, Kuni; Fujii, Hirofumi

    2017-01-01

    To determine whether T2*-weighted MRI has the ability to visualize the irradiated liver parenchyma and liver tumor after irradiation to the previously superparamagnetic iron oxide (SPIO)-accumulated liver. We examined 24 liver tumor-bearing rats. Nine rats (Group 1) received 20 µmol Fe/kg SPIO and subsequent 70-Gy irradiation to the tumor-bearing liver lobe. Four rats (Group 2) received SPIO and sham irradiation. Six rats (Group 3) received saline and irradiation. Finally, five rats (Group 4) received saline and sham irradiation. We acquired sequential 3 Tesla T2*-weighted images of the liver on day 7, and assessed MR image findings including signal intensity of the tumors and tumor-bearing liver lobes. In six rats in Group 1, tumors shrunk by 39-100% (303-0 mm 3 ), and severely, well-defined hypointense irradiated areas were observed. In the other two rats, tumors enlarged by 25 and 172% (595 and 1148 mm 3 ), and hypointense rings surrounded the tumors. The normalized relative signal intensity of the irradiated areas was significantly lower than that of the tumor (0.53 ± 0.06 versus 0.94 ± 0.06; P < 0.05). The severely, well-defined hypointense areas were not observed in the other groups. Histologically, necrotic regions dominated and minimal nonnecrotic tumor cells remained in irradiated areas. The number of CD68-positive cells was higher in irradiated areas than in nonirradiated areas. T2*-weighted MR imaging visualized the irradiated liver parenchyma as markedly, well-defined hypointense areas and liver cancer lesions as hyperintense areas only when SPIO was administered before irradiation. The visualization of the hypointense area was associated with tumor regression after irradiation. 2 J. Magn. Reson. Imaging 2017;45:303-312. © 2016 International Society for Magnetic Resonance in Medicine.

  12. 7 CFR 62.213 - Official identification.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... AGRICULTURAL COMMODITIES (QUALITY SYSTEMS VERIFICATION PROGRAMS) Quality Systems Verification Programs Definitions Service § 62.213 Official identification. The following, as shown in figure 1, constitutes...

  13. Microstructural evolution of neutron-irradiated T91 and NF616 to ~4.3 dpa at 469 °C

    DOE PAGES

    Tan, Lizhen; Kim, B. K.; Yang, Ying; ...

    2017-05-30

    Ferritic-martensitic steels such as T91 and NF616 are candidate materials for several nuclear applications. Here, this study evaluates radiation resistance of T91 and NF616 by examining their microstructural evolutions and hardening after the samples were irradiated in the Advanced Test Reactor to ~4.3 displacements per atom (dpa) at an as-run temperature of 469 °C. In general, this irradiation did not result in significant difference in the radiation-induced microstructures between the two steels. Compared to NF616, T91 had a higher number density of dislocation loops and a lower level of radiation-induced segregation, together with a slightly higher radiation-hardening. Unlike dislocation loopsmore » developed in both steels, radiation-induced cavities were only observed in T91 but remained small with sub-10 nm sizes. Lastly, other than the relatively stable M 23C 6, a new phase (likely Sigma phase) was observed in T91 and radiation-enhanced MX → Z phase transformation was identified in NF616. Laves phase was not observed in the samples.« less

  14. 8 CFR 213a.3 - Notice of change of address.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... SUPPORT ON BEHALF OF IMMIGRANTS § 213a.3 Notice of change of address. (a)(1) If the address of a sponsor... obligation under the affidavit of support remains in effect with respect to any sponsored immigrant, the... 213A(d)(2)(A) of the Act. (ii) If the sponsor, knowing that the sponsored immigrant has received any...

  15. 49 CFR 234.213 - Grounds.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... current power distribution circuits that are grounded in the interest of safety; and common return wires... Maintenance Standards § 234.213 Grounds. Each circuit that affects the proper functioning of a highway-rail... permit a current flow of 75 percent or more of the release value of any relay or electromagnetic device...

  16. Final Report on MEGAPIE Target Irradiation and Post-Irradiation Examination

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yong, Dai

    2015-06-30

    Megawatt pilot experiment (MEGAPIE) was successfully performed in 2006. One of the important goals of MEGAPIE is to understand the behaviour of structural materials of the target components exposed to high fluxes of high-energy protons and spallation neutrons in flowing LBE (liquid lead-bismuth eutectic) environment by conducting post-irradiation examination (PIE). The PIE includes four major parts: non-destructive test, radiochemical analysis of production and distribution of radionuclides produced by spallation reaction in LBE, analysis of LBE corrosion effects on structural materials, T91 and SS 316L steels, and mechanical testing of the T91 and SS 316L steels irradiated in the lower partmore » of the target. The non-destructive test (NDT) including visual inspection and ultrasonic measurement was performed in the proton beam window area of the T91 calotte of the LBE container, the most intensively irradiated part of the MEGAPIE target. The visual inspection showed no visible failure and the ultrasonic measurement demonstrated no detectable change in thickness in the beam window area. Gamma mapping was also performed in the proton beam window area of the AlMg 3 safety-container. The gamma mapping results were used to evaluate the accumulated proton fluence distribution profile, the input data for determining irradiation parameters. Radiochemical analysis of radionuclides produced by spallation reaction in LBE is to improve the understanding of the production and distribution of radionuclides in the target. The results demonstrate that the radionuclides of noble metals, 207Bi, 194Hg/Au are rather homogeneously distributed within the target, while radionuclides of electropositive elements are found to be deposited on the steel-LBE interface. The corrosion effect of LBE on the structural components under intensive irradiation was investigated by metallography. The results show that no evident corrosion damages. However, unexpected deep cracks were found in the

  17. Antimicrobial activity and mechanism of PDC213, an endogenous peptide from human milk.

    PubMed

    Sun, Yazhou; Zhou, Yahui; Liu, Xiao; Zhang, Fan; Yan, Linping; Chen, Ling; Wang, Xing; Ruan, Hongjie; Ji, Chenbo; Cui, Xianwei; Wang, Jiaqin

    2017-02-26

    Human milk has always been considered an ideal source of elemental nutrients to both preterm and full term infants in order to optimally develop the infant's tissues and organs. Recently, hundreds of endogenous milk peptides were identified in human milk. These peptides exhibited angiotensin-converting enzyme inhibition, immunomodulation, or antimicrobial activity. Here, we report the antimicrobial activity and mechanism of a novel type of human antimicrobial peptide (AMP), termed PDC213 (peptide derived from β-Casein 213-226 aa). PDC213 is an endogenous peptide and is present at higher levels in preterm milk than in full term milk. The inhibitory concentration curve and disk diffusion tests showed that PDC213 had obvious antimicrobial against S. aureus and Y. enterocolitica, the common nosocomial pathogens in neonatal intensive care units (NICUs). Fluorescent dye methods, electron microscopy experiments and DNA-binding activity assays further indicated that PDC213 can permeabilize bacterial membranes and cell walls rather than bind intracellular DNA to kill bacteria. Together, our results suggest that PDC213 is a novel type of AMP that warrants further investigation. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. Approaches to Manufacturing Alpha Emitters For Radioimmunotherapeutic Drugs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gaylord King, A.; Givens, Kenneth R.; Miller, William H.

    Several alpha emitting isotopes have been proposed for radioimmunotherapy. To produce these nuclides reliably and in quantities needed, unique manufacturing approaches will be required. This paper describes the approaches that are being developed for the manufacture of 225Actinium (225 Ac) that decays to 213Bismuth (213 Bi) and the commercial manufacturing approaches. Oak Ridge National Laboratory (ORNL) currently supplies the actinium used for research and medical use. Today the ORNL 233U stockpiles only provide sufficient material for research quantities of 213 Bi. At the Institute for Transuranium Elements (ITU), in Karlsruhe, researchers have also developed a method of irradiating radium-226 withmore » protons in a cyclotron to produce actinium- 225 through the reaction 226Ra (p, 2n) 225Ac. Researchers from the Missouri University (MU), the Missouri University Research Reactor (MURR), MedActinium, Inc. and Los Alamos National Laboratory (LANL) are working on a collaborative effort to benchmark and optimize the production of 213Bi via neutron bombardment of 226Ra. MedActinium, Inc., in collaboration with commercial and institutional investigators at PG Research Foundation (PGRF) and Memorial Sloan Kettering Cancer Center (MSKCC), is developing commercial approaches to manufacturing these unique radioimmunotherapeutic drugs.« less

  19. Application of ion exchange and extraction chromatography to the separation of actinium from proton-irradiated thorium metal for analytical purposes.

    PubMed

    Radchenko, V; Engle, J W; Wilson, J J; Maassen, J R; Nortier, F M; Taylor, W A; Birnbaum, E R; Hudston, L A; John, K D; Fassbender, M E

    2015-02-06

    Actinium-225 (t1/2=9.92d) is an α-emitting radionuclide with nuclear properties well-suited for use in targeted alpha therapy (TAT), a powerful treatment method for malignant tumors. Actinium-225 can also be utilized as a generator for (213)Bi (t1/2 45.6 min), which is another valuable candidate for TAT. Actinium-225 can be produced via proton irradiation of thorium metal; however, long-lived (227)Ac (t1/2=21.8a, 99% β(-), 1% α) is co-produced during this process and will impact the quality of the final product. Thus, accurate assays are needed to determine the (225)Ac/(227)Ac ratio, which is dependent on beam energy, irradiation time and target design. Accurate actinium assays, in turn, require efficient separation of actinium isotopes from both the Th matrix and highly radioactive activation by-products, especially radiolanthanides formed from proton-induced fission. In this study, we introduce a novel, selective chromatographic technique for the recovery and purification of actinium isotopes from irradiated Th matrices. A two-step sequence of cation exchange and extraction chromatography was implemented. Radiolanthanides were quantitatively removed from Ac, and no non-Ac radionuclidic impurities were detected in the final Ac fraction. An (225)Ac spike added prior to separation was recovered at ≥ 98%, and Ac decontamination from Th was found to be ≥ 10(6). The purified actinium fraction allowed for highly accurate (227)Ac determination at analytical scales, i.e., at (227)Ac activities of 1-100 kBq (27 nCi to 2.7 μCi). Copyright © 2014 Elsevier B.V. All rights reserved.

  20. 49 CFR Appendix B to Part 213 - Schedule of Civil Penalties

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Schedule of Civil Penalties B Appendix B to Part 213 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD...—Schedule of Civil Penalties Section Violation Willful Violation 1 Subpart A—General: 213.4(a) Excepted...

  1. 49 CFR Appendix B to Part 213 - Schedule of Civil Penalties

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Schedule of Civil Penalties B Appendix B to Part 213 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD...—Schedule of Civil Penalties Section Violation Willful Violation 1 Subpart A—General: 213.4(a) Excepted...

  2. 49 CFR Appendix B to Part 213 - Schedule of Civil Penalties

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Schedule of Civil Penalties B Appendix B to Part 213 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD...—Schedule of Civil Penalties Section Violation Willful Violation 1 Subpart A—General: 213.4(a) Excepted...

  3. Don't Give Up! Practical Strategies for Challenging Collaborations

    ERIC Educational Resources Information Center

    Cramer, Sharon; Stivers, Jan

    2007-01-01

    People faced with collaboration challenges are often reluctant to be honest about problems because in many schools collaboration is a norm. But whereas most special educators are intuitively skilled at working with others, "problematic professional encounters are inevitable barriers that will appear occasionally in the life of every special…

  4. 48 CFR 213.270 - Use of the Governmentwide commercial purchase card.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Use of the Governmentwide commercial purchase card. 213.270 Section 213.270 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SIMPLIFIED ACQUISITION PROCEDURES Actions at or Below the...

  5. Total-skin electron irradiation for cutaneous T-cell lymphoma: the Northern Israel Oncology Center experience.

    PubMed

    Kuten, A; Stein, M; Mandelzweig, Y; Tatcher, M; Yaacov, G; Epelbaum, R; Rosenblatt, E

    1991-07-01

    Total-skin electron irradiation (TSEI) is effective and frequently used in the treatment of cutaneous T-cell lymphoma. A treatment technique has been developed at our center, using the Philips SL 75/10 linear accelerator. In our method, the patient is irradiated in a recumbent position by five pairs of uncollimated electron beams at a source to skin distance of 150 cm. This method provides a practical solution to clinical requirements with respect to uniformity of electron dose and low X-ray contamination. Its implementation does not require special equipment or modification of the linear accelerator, 19 of 23 patients (83%) with mycosis fungoides, treated by this method, achieved complete regression of their cutaneous lesions.

  6. 14 CFR 61.213 - Eligibility requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) AIRMEN CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS Ground Instructors § 61.213...) Student evaluation and testing; (iv) Course development; (v) Lesson planning; and (vi) Classroom training...) Holds a ground instructor certificate or flight instructor certificate issued under this part; (2) Holds...

  7. 14 CFR 61.213 - Eligibility requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) AIRMEN CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS Ground Instructors § 61.213...) Student evaluation and testing; (iv) Course development; (v) Lesson planning; and (vi) Classroom training...) Holds a ground instructor certificate or flight instructor certificate issued under this part; (2) Holds...

  8. 14 CFR 61.213 - Eligibility requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) AIRMEN CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS Ground Instructors § 61.213...) Student evaluation and testing; (iv) Course development; (v) Lesson planning; and (vi) Classroom training...) Holds a ground instructor certificate or flight instructor certificate issued under this part; (2) Holds...

  9. WE-AB-213-01: AAPM Projects and Collaborations in Africa

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shulman, A.

    AAPM projects and collaborations in Africa Adam Shulman (AA-SC Chair) The African Affairs Subcommittee (AA-SC) of the AAPM will present a multi-institutional approach to medical physics support in Africa. Current work to increase the quality of care and level of safety for the medical physics practice in Senegal, Ghana, and Zimbabwe will be presented, along with preliminary projects in Nigeria and Botswana. Because the task of addressing the needs of medical physics in countries across Africa is larger than one entity can accomplish on its own, the AA-SC has taken the approach of joining forces with multiple organizations such asmore » Radiating Hope and TreatSafely (NGO’s), the IAEA, companies like BrainLab, Varian and Elekta, medical volunteers and academic institutions such as NYU and Washington University. Elements of current projects include: 1) Distance training and evaluation of the quality of contouring and treatment planning, teaching treatment planning and other subjects, and troubleshooting using modern telecommunications technology in Senegal, Ghana, and Zimbabwe; 2) Assistance in the transition from 2D to 3D in Senegal and Zimbabwe; 3) Assistance in the transition from 3D to IMRT using in-house compensators in Senegal; 4) Modernizing the cancer center in Senegal and increasing safety and; 5) Training on on 3D techniques in Ghana; 6) Assisting a teaching and training radiation oncology center to be built in Zimbabwe; 7) Working with the ISEP Program in Sub-Saharan Africa; 8) Creating instructional videos on linac commissioning; 9) Working on a possible collaboration to train physicists in Nigeria. Building on past achievements, the subcommittee seeks to make a larger impact on the continent, as the number and size of projects increases and more human resources become available. The State of Medical Physics Collaborations and Projects in Latin America Sandra Guzman (Peru) The lack of Medical Physicists (MP) in many Latin American (LA) countries leads

  10. 41 CFR 302-3.213 - What allowances will I receive for tour renewal travel?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 41 Public Contracts and Property Management 4 2011-07-01 2011-07-01 false What allowances will I receive for tour renewal travel? 302-3.213 Section 302-3.213 Public Contracts and Property Management... SPECIFIC TYPE Types of Transfers Overseas Tour Renewal Agreement § 302-3.213 What allowances will I receive...

  11. 41 CFR 302-3.213 - What allowances will I receive for tour renewal travel?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 41 Public Contracts and Property Management 4 2014-07-01 2014-07-01 false What allowances will I receive for tour renewal travel? 302-3.213 Section 302-3.213 Public Contracts and Property Management... SPECIFIC TYPE Types of Transfers Overseas Tour Renewal Agreement § 302-3.213 What allowances will I receive...

  12. 41 CFR 302-3.213 - What allowances will I receive for tour renewal travel?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 4 2013-07-01 2012-07-01 true What allowances will I receive for tour renewal travel? 302-3.213 Section 302-3.213 Public Contracts and Property Management... SPECIFIC TYPE Types of Transfers Overseas Tour Renewal Agreement § 302-3.213 What allowances will I receive...

  13. 41 CFR 302-3.213 - What allowances will I receive for tour renewal travel?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 41 Public Contracts and Property Management 4 2012-07-01 2012-07-01 false What allowances will I receive for tour renewal travel? 302-3.213 Section 302-3.213 Public Contracts and Property Management... SPECIFIC TYPE Types of Transfers Overseas Tour Renewal Agreement § 302-3.213 What allowances will I receive...

  14. 41 CFR 302-3.213 - What allowances will I receive for tour renewal travel?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false What allowances will I receive for tour renewal travel? 302-3.213 Section 302-3.213 Public Contracts and Property Management... SPECIFIC TYPE Types of Transfers Overseas Tour Renewal Agreement § 302-3.213 What allowances will I receive...

  15. 8 CFR 213a.5 - Relationship of this part to other affidavits of support.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Relationship of this part to other affidavits of support. 213a.5 Section 213a.5 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS AFFIDAVITS OF SUPPORT ON BEHALF OF IMMIGRANTS § 213a.5 Relationship of this part to...

  16. 24 CFR 213.259a - Premiums-mortgages insured pursuant to section 238(c) of the Act.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    .... All of the provisions of §§ 213.253 through 213.259 governing mortgage insurance premiums shall apply... mortgage insurance premiums due on such mortgages in accordance with §§ 213.253 through 213.259 shall be... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Premiums-mortgages insured pursuant...

  17. 24 CFR 213.259a - Premiums-mortgages insured pursuant to section 238(c) of the Act.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    .... All of the provisions of §§ 213.253 through 213.259 governing mortgage insurance premiums shall apply... mortgage insurance premiums due on such mortgages in accordance with §§ 213.253 through 213.259 shall be... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Premiums-mortgages insured pursuant...

  18. 30 CFR 250.213 - What general information must accompany the EP?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...? 250.213 Section 250.213 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR... carry out your proposed exploration activities, include a statement so indicating. (e) Bonds, oil spill... facilities proposed in your EP are or will be covered by an appropriate bond under 30 CFR part 256, subpart I...

  19. 14 CFR 213.7 - Filing requirements for adherence to Montreal Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Filing requirements for adherence to Montreal Agreement. 213.7 Section 213.7 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF... part 203 of this chapter. That form can be obtained from the Foreign Air Carrier Licensing Division (X...

  20. 33 CFR 117.213 - New Haven Harbor, Quinnipiac and Mill Rivers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Mill Rivers. 117.213 Section 117.213 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Haven Harbor, Quinnipiac and Mill Rivers. The draws of the Tomlinson bridge, mile 0.0, the Ferry Street... bridge, mile 0.4 across Mill River, shall operate as follows: (a) The draws shall open on signal; except...

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