Sample records for tab-delimited text files

  1. jmzTab: a java interface to the mzTab data standard.

    PubMed

    Xu, Qing-Wei; Griss, Johannes; Wang, Rui; Jones, Andrew R; Hermjakob, Henning; Vizcaíno, Juan Antonio

    2014-06-01

    mzTab is the most recent standard format developed by the Proteomics Standards Initiative. mzTab is a flexible tab-delimited file that can capture identification and quantification results coming from MS-based proteomics and metabolomics approaches. We here present an open-source Java application programming interface for mzTab called jmzTab. The software allows the efficient processing of mzTab files, providing read and write capabilities, and is designed to be embedded in other software packages. The second key feature of the jmzTab model is that it provides a flexible framework to maintain the logical integrity between the metadata and the table-based sections in the mzTab files. In this article, as two example implementations, we also describe two stand-alone tools that can be used to validate mzTab files and to convert PRIDE XML files to mzTab. The library is freely available at http://mztab.googlecode.com. © 2014 The Authors PROTEOMICS Published by Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. TabSQL: a MySQL tool to facilitate mapping user data to public databases.

    PubMed

    Xia, Xiao-Qin; McClelland, Michael; Wang, Yipeng

    2010-06-23

    With advances in high-throughput genomics and proteomics, it is challenging for biologists to deal with large data files and to map their data to annotations in public databases. We developed TabSQL, a MySQL-based application tool, for viewing, filtering and querying data files with large numbers of rows. TabSQL provides functions for downloading and installing table files from public databases including the Gene Ontology database (GO), the Ensembl databases, and genome databases from the UCSC genome bioinformatics site. Any other database that provides tab-delimited flat files can also be imported. The downloaded gene annotation tables can be queried together with users' data in TabSQL using either a graphic interface or command line. TabSQL allows queries across the user's data and public databases without programming. It is a convenient tool for biologists to annotate and enrich their data.

  3. TabSQL: a MySQL tool to facilitate mapping user data to public databases

    PubMed Central

    2010-01-01

    Background With advances in high-throughput genomics and proteomics, it is challenging for biologists to deal with large data files and to map their data to annotations in public databases. Results We developed TabSQL, a MySQL-based application tool, for viewing, filtering and querying data files with large numbers of rows. TabSQL provides functions for downloading and installing table files from public databases including the Gene Ontology database (GO), the Ensembl databases, and genome databases from the UCSC genome bioinformatics site. Any other database that provides tab-delimited flat files can also be imported. The downloaded gene annotation tables can be queried together with users' data in TabSQL using either a graphic interface or command line. Conclusions TabSQL allows queries across the user's data and public databases without programming. It is a convenient tool for biologists to annotate and enrich their data. PMID:20573251

  4. Text File Comparator

    NASA Technical Reports Server (NTRS)

    Kotler, R. S.

    1983-01-01

    File Comparator program IFCOMP, is text file comparator for IBM OS/VScompatable systems. IFCOMP accepts as input two text files and produces listing of differences in pseudo-update form. IFCOMP is very useful in monitoring changes made to software at the source code level.

  5. Tabular data and graphical images in support of the U.S. Geological Survey National Oil and Gas Assessment -- San Joaquin Basin (5010): Chapter 28 in Petroleum systems and geologic assessment of oil and gas in the San Joaquin Basin Province, California

    USGS Publications Warehouse

    Klett, T.R.; Le, P.A.

    2007-01-01

    This chapter describes data used in support of the assessment process. Digital tabular data used in this report and archival data that permit the user to perform further analyses are available elsewhere on this CD–ROM. Computers and software may import the data without transcription from the portable document format (.pdf) files of the text by the reader. Because of the number and variety of platforms and software available, graphical images are provided as .pdf files and tabular data are provided in a raw form as tab-delimited text files (.tab files).

  6. Tabular data and graphical images in support of the U.S. Geological Survey National Oil and Gas Assessment--San Juan Basin Province (5022): Chapter 7 in Total petroleum systems and geologic assessment of undiscovered oil and gas resources in the San Juan Basin Province, exclusive of Paleozoic rocks, New Mexico and Colorado

    USGS Publications Warehouse

    Klett, T.R.; Le, P.A.

    2013-01-01

    This chapter describes data used in support of the process being applied by the U.S. Geological Survey (USGS) National Oil and Gas Assessment (NOGA) project. Digital tabular data used in this report and archival data that permit the user to perform further analyses are available elsewhere on this CD–ROM. Computers and software may import the data without transcription from the Portable Document Format files (.pdf files) of the text by the reader. Because of the number and variety of platforms and software available, graphical images are provided as .pdf files and tabular data are provided in a raw form as tab-delimited text files (.tab files).

  7. Chapter 3: Tabular Data and Graphical Images in Support of the U.S. Geological Survey National Oil and Gas Assessment - Western Gulf Province, Smackover-Austin-Eagle Ford Composite Total Petroleum System (504702)

    USGS Publications Warehouse

    Klett, T.R.; Le, P.A.

    2006-01-01

    This chapter describes data used in support of the process being applied by the U.S. Geological Survey (USGS) National Oil and Gas Assessment (NOGA) project. Digital tabular data used in this report and archival data that permit the user to perform further analyses are available elsewhere on this CD-ROM. Computers and software may import the data without transcription from the Portable Document Format files (.pdf files) of the text by the reader. Because of the number and variety of platforms and software available, graphical images are provided as .pdf files and tabular data are provided in a raw form as tab-delimited text files (.tab files).

  8. Chapter 6. Tabular data and graphical images in support of the U.S. Geological Survey National Oil and Gas Assessment-East Texas basin and Louisiana-Mississippi salt basins provinces, Jurassic Smackover interior salt basins total petroleum system (504902), Travis Peak and Hosston formations.

    USGS Publications Warehouse

    ,

    2006-01-01

    This chapter describes data used in support of the process being applied by the U.S. Geological Survey (USGS) National Oil and Gas Assessment (NOGA) project. Digital tabular data used in this report and archival data that permit the user to perform further analyses are available elsewhere on the CD-ROM. Computers and software may import the data without transcription from the Portable Document Format files (.pdf files) of the text by the reader. Because of the number and variety of platforms and software available, graphical images are provided as .pdf files and tabular data are provided in a raw form as tab-delimited text files (.tab files).

  9. Chapter 2: Tabular Data and Graphical Images in Support of the U.S. Geological Survey National Oil and Gas Assessment - The Wind River Basin Province

    USGS Publications Warehouse

    Klett, T.R.; Le, P.A.

    2007-01-01

    This chapter describes data used in support of the process being applied by the U.S. Geological Survey (USGS) National Oil and Gas Assessment (NOGA) project. Digital tabular data used in this report and archival data that permit the user to perform further analyses are available elsewhere on this CD-ROM. Computers and software may import the data without transcription from the Portable Document Format files (.pdf files) of the text by the reader. Graphical images are provided as .pdf files and tabular data are provided in a raw form as tab-delimited text files (.tab files) because of the number and variety of platforms and software available.

  10. Chapter 3. Tabular data and graphical images in support of the U.S. Geological Survey National Oil and Gas Assessment--East Texas basin and Louisiana-Mississippi salt basins provinces, Jurassic Smackover Interior salt basins total petroleum system (504902), Cotton Valley group.

    USGS Publications Warehouse

    Klett, T.R.; Le, P.A.

    2006-01-01

    This chapter describes data used in support of the process being applied by the U.S. Geological Survey (USGS) National Oil and Gas Assessment (NOGA) project. Digital tabular data used in this report and archival data that permit the user to perform further analyses are available elsewhere on the CD-ROM. Computers and software may import the data without transcription from the Portable Document Format files (.pdf files) of the text by the reader. Because of the number and variety of platforms and software available, graphical images are provided as .pdf files and tabular data are provided in a raw form as tab-delimited text files (.tab files).

  11. User's manual for the generalized computer program system. Open-channel flow and sedimentation, TABS-2. Main text

    NASA Astrophysics Data System (ADS)

    Thomas, W. A.; McAnally, W. H., Jr.

    1985-07-01

    TABS-2 is a generalized numerical modeling system for open-channel flows, sedimentation, and constituent transport. It consists of more than 40 computer programs to perform modeling and related tasks. The major modeling components--RMA-2V, STUDH, and RMA-4--calculate two-dimensional, depth-averaged flows, sedimentation, and dispersive transport, respectively. The other programs in the system perform digitizing, mesh generation, data management, graphical display, output analysis, and model interfacing tasks. Utilities include file management and automatic generation of computer job control instructions. TABS-2 has been applied to a variety of waterways, including rivers, estuaries, bays, and marshes. It is designed for use by engineers and scientists who may not have a rigorous computer background. Use of the various components is described in Appendices A-O. The bound version of the report does not include the appendices. A looseleaf form with Appendices A-O is distributed to system users.

  12. Altimeter Processing Tools for Analyzing Mesoscale Ocean Features

    DTIC Science & Technology

    1990-09-01

    However, since the programs are modular, users can easily use their own orbit and geoid corrections to study basin scale problems. We left programs that...g..repeat c*/c*.a002c > a002cs-m or %g.repeat c???/c???.a002c > a002cs-m The file aOO2cs.m contains the following information in tab delimited ...information in tab delimited columns: The sea surface height residual files are similar to those created by g.repeat. except that fi(z ,t) is the original

  13. mzML2ISA & nmrML2ISA: generating enriched ISA-Tab metadata files from metabolomics XML data

    PubMed Central

    Larralde, Martin; Lawson, Thomas N.; Weber, Ralf J. M.; Moreno, Pablo; Haug, Kenneth; Rocca-Serra, Philippe; Viant, Mark R.; Steinbeck, Christoph; Salek, Reza M.

    2017-01-01

    Abstract Summary Submission to the MetaboLights repository for metabolomics data currently places the burden of reporting instrument and acquisition parameters in ISA-Tab format on users, who have to do it manually, a process that is time consuming and prone to user input error. Since the large majority of these parameters are embedded in instrument raw data files, an opportunity exists to capture this metadata more accurately. Here we report a set of Python packages that can automatically generate ISA-Tab metadata file stubs from raw XML metabolomics data files. The parsing packages are separated into mzML2ISA (encompassing mzML and imzML formats) and nmrML2ISA (nmrML format only). Overall, the use of mzML2ISA & nmrML2ISA reduces the time needed to capture metadata substantially (capturing 90% of metadata on assay and sample levels), is much less prone to user input errors, improves compliance with minimum information reporting guidelines and facilitates more finely grained data exploration and querying of datasets. Availability and Implementation mzML2ISA & nmrML2ISA are available under version 3 of the GNU General Public Licence at https://github.com/ISA-tools. Documentation is available from http://2isa.readthedocs.io/en/latest/. Contact reza.salek@ebi.ac.uk or isatools@googlegroups.com Supplementary information Supplementary data are available at Bioinformatics online. PMID:28402395

  14. mzML2ISA & nmrML2ISA: generating enriched ISA-Tab metadata files from metabolomics XML data.

    PubMed

    Larralde, Martin; Lawson, Thomas N; Weber, Ralf J M; Moreno, Pablo; Haug, Kenneth; Rocca-Serra, Philippe; Viant, Mark R; Steinbeck, Christoph; Salek, Reza M

    2017-08-15

    Submission to the MetaboLights repository for metabolomics data currently places the burden of reporting instrument and acquisition parameters in ISA-Tab format on users, who have to do it manually, a process that is time consuming and prone to user input error. Since the large majority of these parameters are embedded in instrument raw data files, an opportunity exists to capture this metadata more accurately. Here we report a set of Python packages that can automatically generate ISA-Tab metadata file stubs from raw XML metabolomics data files. The parsing packages are separated into mzML2ISA (encompassing mzML and imzML formats) and nmrML2ISA (nmrML format only). Overall, the use of mzML2ISA & nmrML2ISA reduces the time needed to capture metadata substantially (capturing 90% of metadata on assay and sample levels), is much less prone to user input errors, improves compliance with minimum information reporting guidelines and facilitates more finely grained data exploration and querying of datasets. mzML2ISA & nmrML2ISA are available under version 3 of the GNU General Public Licence at https://github.com/ISA-tools. Documentation is available from http://2isa.readthedocs.io/en/latest/. reza.salek@ebi.ac.uk or isatools@googlegroups.com. Supplementary data are available at Bioinformatics online. © The Author(s) 2017. Published by Oxford University Press.

  15. Individualized texting for adherence building (iTAB): improving antiretroviral dose timing among HIV-infected persons with co-occurring bipolar disorder.

    PubMed

    Moore, David J; Poquette, Amelia; Casaletto, Kaitlin B; Gouaux, Ben; Montoya, Jessica L; Posada, Carolina; Rooney, Alexandra S; Badiee, Jayraan; Deutsch, Reena; Letendre, Scott L; Depp, Colin A; Grant, Igor; Atkinson, J Hampton

    2015-03-01

    HIV+ persons with co-occurring bipolar disorder (HIV+/BD+) have elevated rates of medication nonadherence. We conducted a 30-day randomized controlled trial of a two-way, text messaging system, iTAB (n = 25), compared to an active comparison (CTRL) (n = 25) to improve antiretroviral (ARV) and psychotropic (PSY) adherence and dose timing. Both groups received medication adherence psychoeducation and daily texts assessing mood. The iTAB group additionally received personalized medication reminder texts. Participants responded to over 90 % of the mood and adherence text messages. Mean adherence, as assessed via electronic monitoring caps, was high and comparable between groups for both ARV (iTAB 86.2 % vs. CTRL 84.8 %; p = 0.95, Cliff's d = 0.01) and PSY (iTAB 78.9 % vs. CTRL 77.3 %; p = 0.43, Cliff's d = -0.13) medications. However, iTAB participants took ARVs significantly closer to their intended dosing time than CTRL participants (iTAB: 27.8 vs. CTRL: 77.0 min from target time; p = 0.02, Cliff's d = 0.37). There was no group difference on PSY dose timing. Text messaging interventions may represent a low-burden approach to improving timeliness of medication-taking behaviors among difficult-to-treat populations. The benefits of improved dose timing for long-term medication adherence require additional investigation.

  16. Individualized Texting for Adherence Building (iTAB): Improving Antiretroviral Dose Timing Among HIV-Infected Persons with Co-occurring Bipolar Disorder

    PubMed Central

    Poquette, Amelia; Casaletto, Kaitlin B.; Gouaux, Ben; Montoya, Jessica L.; Posada, Carolina; Rooney, Alexandra S.; Badiee, Jayraan; Deutsch, Reena; Letendre, Scott L.; Depp, Colin A.; Grant, Igor; Atkinson, J. Hampton

    2015-01-01

    HIV+ persons with co-occurring bipolar disorder (HIV+/BD+) have elevated rates of medication nonadherence. We conducted a 30-day randomized controlled trial of a two-way, text messaging system, iTAB (n = 25), compared to an active comparison (CTRL) (n = 25) to improve antiretroviral (ARV) and psychotropic (PSY) adherence and dose timing. Both groups received medication adherence psychoeducation and daily texts assessing mood. The iTAB group additionally received personalized medication reminder texts. Participants responded to over 90 % of the mood and adherence text messages. Mean adherence, as assessed via electronic monitoring caps, was high and comparable between groups for both ARV (iTAB 86.2 % vs. CTRL 84.8 %; p = 0.95, Cliff’s d = 0.01) and PSY (iTAB 78.9 % vs. CTRL 77.3 %; p = 0.43, Cliff’s d = −0.13) medications. However, iTAB participants took ARVs significantly closer to their intended dosing time than CTRL participants (iTAB: 27.8 vs. CTRL: 77.0 min from target time; p = 0.02, Cliff’s d = 0.37). There was no group difference on PSY dose timing. Text messaging interventions may represent a low-burden approach to improving timeliness of medication-taking behaviors among difficult-to-treat populations. The benefits of improved dose timing for long-term medication adherence require additional investigation. PMID:25504449

  17. Statistical Analysis of the Skaion Network Security Dataset

    DTIC Science & Technology

    2012-09-01

    DataType :=xlDelimited, _ TextQualifier:=xlDoubleQuote, ConsecutiveDelimiter:=True, Tab:=False, _ Semicolon:=False, Comma:=False, Space...Selection.TextToColumns Destination:=Range(“E1”), DataType :=xlDelimited, _ TextQualifier:=xlDoubleQuote, ConsecutiveDelimiter:=True, Tab:=False...True Columns(“F:F”).Select Selection.TextToColumns Destination:=Range(“F1”), DataType :=xlDelimited, _ TextQualifier:=xlDoubleQuote

  18. ISA-TAB-Nano: a specification for sharing nanomaterial research data in spreadsheet-based format.

    PubMed

    Thomas, Dennis G; Gaheen, Sharon; Harper, Stacey L; Fritts, Martin; Klaessig, Fred; Hahn-Dantona, Elizabeth; Paik, David; Pan, Sue; Stafford, Grace A; Freund, Elaine T; Klemm, Juli D; Baker, Nathan A

    2013-01-14

    The high-throughput genomics communities have been successfully using standardized spreadsheet-based formats to capture and share data within labs and among public repositories. The nanomedicine community has yet to adopt similar standards to share the diverse and multi-dimensional types of data (including metadata) pertaining to the description and characterization of nanomaterials. Owing to the lack of standardization in representing and sharing nanomaterial data, most of the data currently shared via publications and data resources are incomplete, poorly-integrated, and not suitable for meaningful interpretation and re-use of the data. Specifically, in its current state, data cannot be effectively utilized for the development of predictive models that will inform the rational design of nanomaterials. We have developed a specification called ISA-TAB-Nano, which comprises four spreadsheet-based file formats for representing and integrating various types of nanomaterial data. Three file formats (Investigation, Study, and Assay files) have been adapted from the established ISA-TAB specification; while the Material file format was developed de novo to more readily describe the complexity of nanomaterials and associated small molecules. In this paper, we have discussed the main features of each file format and how to use them for sharing nanomaterial descriptions and assay metadata. The ISA-TAB-Nano file formats provide a general and flexible framework to record and integrate nanomaterial descriptions, assay data (metadata and endpoint measurements) and protocol information. Like ISA-TAB, ISA-TAB-Nano supports the use of ontology terms to promote standardized descriptions and to facilitate search and integration of the data. The ISA-TAB-Nano specification has been submitted as an ASTM work item to obtain community feedback and to provide a nanotechnology data-sharing standard for public development and adoption.

  19. ISA-TAB-Nano: A Specification for Sharing Nanomaterial Research Data in Spreadsheet-based Format

    PubMed Central

    2013-01-01

    Background and motivation The high-throughput genomics communities have been successfully using standardized spreadsheet-based formats to capture and share data within labs and among public repositories. The nanomedicine community has yet to adopt similar standards to share the diverse and multi-dimensional types of data (including metadata) pertaining to the description and characterization of nanomaterials. Owing to the lack of standardization in representing and sharing nanomaterial data, most of the data currently shared via publications and data resources are incomplete, poorly-integrated, and not suitable for meaningful interpretation and re-use of the data. Specifically, in its current state, data cannot be effectively utilized for the development of predictive models that will inform the rational design of nanomaterials. Results We have developed a specification called ISA-TAB-Nano, which comprises four spreadsheet-based file formats for representing and integrating various types of nanomaterial data. Three file formats (Investigation, Study, and Assay files) have been adapted from the established ISA-TAB specification; while the Material file format was developed de novo to more readily describe the complexity of nanomaterials and associated small molecules. In this paper, we have discussed the main features of each file format and how to use them for sharing nanomaterial descriptions and assay metadata. Conclusion The ISA-TAB-Nano file formats provide a general and flexible framework to record and integrate nanomaterial descriptions, assay data (metadata and endpoint measurements) and protocol information. Like ISA-TAB, ISA-TAB-Nano supports the use of ontology terms to promote standardized descriptions and to facilitate search and integration of the data. The ISA-TAB-Nano specification has been submitted as an ASTM work item to obtain community feedback and to provide a nanotechnology data-sharing standard for public development and adoption. PMID

  20. Molecular species delimitation methods recover most song-delimited cicada species in the European Cicadetta montana complex.

    PubMed

    Wade, E J; Hertach, T; Gogala, M; Trilar, T; Simon, C

    2015-12-01

    Molecular species delimitation is increasingly being used to discover and illuminate species level diversity, and a number of methods have been developed. Here, we compare the ability of two molecular species delimitation methods to recover song-delimited species in the Cicadetta montana cryptic species complex throughout Europe. Recent bioacoustics studies of male calling songs (premating reproductive barriers) have revealed cryptic species diversity in this complex. Maximum likelihood and Bayesian phylogenetic analyses were used to analyse the mitochondrial genes COI and COII and the nuclear genes EF1α and period for thirteen European Cicadetta species as well as the closely related monotypic genus Euboeana. Two molecular species delimitation methods, general mixed Yule-coalescent (GMYC) and Bayesian phylogenetics and phylogeography, identified the majority of song-delimited species and were largely congruent with each other. None of the molecular delimitation methods were able to fully recover a recent radiation of four Greek species. © 2015 European Society For Evolutionary Biology. Journal of Evolutionary Biology © 2015 European Society For Evolutionary Biology.

  1. Extract and visualize geolocation from any text file

    NASA Astrophysics Data System (ADS)

    Boustani, M.

    2015-12-01

    There are variety of text file formats such as PDF, HTML and more which contains words about locations(countries, cities, regions and more). GeoParser developed as one of sub-projects under DARPA Memex to help finding any geolocation information crawled website data. It is a web application benefiting from Apache Tika to extract locations from any text file format and visualize geolocations on the map. https://github.com/MBoustani/GeoParserhttps://github.com/chrismattmann/tika-pythonhttp://www.darpa.mil/program/memex

  2. An EXCEL macro for importing log ASCII standard (LAS) files into EXCEL worksheets

    NASA Astrophysics Data System (ADS)

    Özkaya, Sait Ismail

    1996-02-01

    An EXCEL 5.0 macro is presented for converting a LAS text file into an EXCEL worksheet. Although EXCEL has commands for importing text files and parsing text lines, LAS files must be decoded line-by-line because three different delimiters are used to separate fields of differing length. The macro is intended to eliminate manual decoding of LAS version 2.0. LAS is a floppy disk format for storage and transfer of log data as text files. LAS was proposed by the Canadian Well Logging Society. The present EXCEL macro decodes different sections of a LAS file, separates, and places the fields into different columns of an EXCEL worksheet. To import a LAS file into EXCEL without errors, the file must not contain any unrecognized symbols, and the data section must be the last section. The program does not check for the presence of mandatory sections or fields as required by LAS rules. Once a file is incorporated into EXCEL, mandatory sections and fields may be inspected visually.

  3. The Species Delimitation Uncertainty Principle

    PubMed Central

    Adams, Byron J.

    2001-01-01

    If, as Einstein said, "it is the theory which decides what we can observe," then "the species problem" could be solved by simply improving our theoretical definition of what a species is. However, because delimiting species entails predicting the historical fate of evolutionary lineages, species appear to behave according to the Heisenberg Uncertainty Principle, which states that the most philosophically satisfying definitions of species are the least operational, and as species concepts are modified to become more operational they tend to lose their philosophical integrity. Can species be delimited operationally without losing their philosophical rigor? To mitigate the contingent properties of species that tend to make them difficult for us to delimit, I advocate a set of operations that takes into account the prospective nature of delimiting species. Given the fundamental role of species in studies of evolution and biodiversity, I also suggest that species delimitation proceed within the context of explicit hypothesis testing, like other scientific endeavors. The real challenge is not so much the inherent fallibility of predicting the future but rather adequately sampling and interpreting the evidence available to us in the present. PMID:19265874

  4. Inhibition of autophagy by TAB2 and TAB3

    PubMed Central

    Criollo, Alfredo; Niso-Santano, Mireia; Malik, Shoaib Ahmad; Michaud, Mickael; Morselli, Eugenia; Mariño, Guillermo; Lachkar, Sylvie; Arkhipenko, Alexander V; Harper, Francis; Pierron, Gérard; Rain, Jean-Christophe; Ninomiya-Tsuji, Jun; Fuentes, José M; Lavandero, Sergio; Galluzzi, Lorenzo; Maiuri, Maria Chiara; Kroemer, Guido

    2011-01-01

    Autophagic responses are coupled to the activation of the inhibitor of NF-κB kinase (IKK). Here, we report that the essential autophagy mediator Beclin 1 and TGFβ-activated kinase 1 (TAK1)-binding proteins 2 and 3 (TAB2 and TAB3), two upstream activators of the TAK1-IKK signalling axis, constitutively interact with each other via their coiled-coil domains (CCDs). Upon autophagy induction, TAB2 and TAB3 dissociate from Beclin 1 and bind TAK1. Moreover, overexpression of TAB2 and TAB3 suppresses, while their depletion triggers, autophagy. The expression of the C-terminal domain of TAB2 or TAB3 or that of the CCD of Beclin 1 competitively disrupts the interaction between endogenous Beclin 1, TAB2 and TAB3, hence stimulating autophagy through a pathway that requires endogenous Beclin 1, TAK1 and IKK to be optimally efficient. These results point to the existence of an autophagy-stimulatory ‘switch' whereby TAB2 and TAB3 abandon inhibitory interactions with Beclin 1 to engage in a stimulatory liaison with TAK1. PMID:22081109

  5. Inhibition of autophagy by TAB2 and TAB3.

    PubMed

    Criollo, Alfredo; Niso-Santano, Mireia; Malik, Shoaib Ahmad; Michaud, Mickael; Morselli, Eugenia; Mariño, Guillermo; Lachkar, Sylvie; Arkhipenko, Alexander V; Harper, Francis; Pierron, Gérard; Rain, Jean-Christophe; Ninomiya-Tsuji, Jun; Fuentes, José M; Lavandero, Sergio; Galluzzi, Lorenzo; Maiuri, Maria Chiara; Kroemer, Guido

    2011-11-11

    Autophagic responses are coupled to the activation of the inhibitor of NF-κB kinase (IKK). Here, we report that the essential autophagy mediator Beclin 1 and TGFβ-activated kinase 1 (TAK1)-binding proteins 2 and 3 (TAB2 and TAB3), two upstream activators of the TAK1-IKK signalling axis, constitutively interact with each other via their coiled-coil domains (CCDs). Upon autophagy induction, TAB2 and TAB3 dissociate from Beclin 1 and bind TAK1. Moreover, overexpression of TAB2 and TAB3 suppresses, while their depletion triggers, autophagy. The expression of the C-terminal domain of TAB2 or TAB3 or that of the CCD of Beclin 1 competitively disrupts the interaction between endogenous Beclin 1, TAB2 and TAB3, hence stimulating autophagy through a pathway that requires endogenous Beclin 1, TAK1 and IKK to be optimally efficient. These results point to the existence of an autophagy-stimulatory 'switch' whereby TAB2 and TAB3 abandon inhibitory interactions with Beclin 1 to engage in a stimulatory liaison with TAK1.

  6. Delimiting communities in the Pacific Northwest.

    Treesearch

    Ellen M. Donoghue

    2003-01-01

    The paper presents an approach for delimiting communities in the Northwest Forest Plan (NWFP) region of the Pacific Northwest that responds to the need to assess impacts and issues associated with broad-scale ecosystem management. Census block groups are aggregated to provide an alternative to more commonly used geographic delimitations of communities, specifically...

  7. Evaluation Data of a High Temperature COTS Flash Memory Module (TI SM28VLT32) for Use in Geothermal Electronics Packages

    DOE Data Explorer

    Cashion, Avery

    2014-08-29

    The accompanying raw data is composslection. Each file is 3 columns and tab-delimited with the first column being the data address, the second column being the first byte of the data, and the third column being the second byte of the data.

  8. GIDEP Batching Tool

    NASA Technical Reports Server (NTRS)

    Fong, Danny; Odell,Dorice; Barry, Peter; Abrahamian, Tomik

    2008-01-01

    This software provides internal, automated search mechanics of GIDEP (Government- Industry Data Exchange Program) Alert data imported from the GIDEP government Web site. The batching tool allows the import of a single parts list in tab-delimited text format into the local JPL GIDEP database. Delimiters from every part number are removed. The original part numbers with delimiters are compared, as well as the newly generated list without the delimiters. The two lists run against the GIDEP imports, and output any matches. This feature only works with Netscape 2.0 or greater, or Internet Explorer 4.0 or greater. The user selects the browser button to choose a text file to import. When the submit button is pressed, this script will import alerts from the text file into the local JPL GIDEP database. This batch tool provides complete in-house control over exported material and data for automated batch match abilities. The batching tool has the ability to match capabilities of the parts list to tables, and yields results that aid further research and analysis. This provides more control over GIDEP information for metrics and reports information not provided by the government site. This software yields results quickly and gives more control over external data from the government site in order to generate other reports not available from the external source. There is enough space to store years of data. The program relates to risk identification and management with regard to projects and GIDEP alert information encompassing flight parts for space exploration.

  9. Species Delimitation and Global Biosecurity

    PubMed Central

    Boykin, Laura M.; Armstrong, Karen F.; Kubatko, Laura; De Barro, Paul

    2012-01-01

    Species delimitation directly impacts on global biosecurity. It is a critical element in the decisions made by national governments in regard to the flow of trade and to the biosecurity measures imposed to protect countries from the threat of invasive species. Here we outline a novel approach to species delimitation, “tip to root”, for two highly invasive insect pests, Bemisia tabaci (sweetpotato whitefly) and Lymantria dispar (Asian gypsy moth). Both species are of concern to biosecurity, but illustrate the extremes of phylogenetic resolution that present the most complex delimitation issues for biosecurity; B. tabaci having extremely high intra-specific genetic variability and L. dispar composed of relatively indistinct subspecies. This study tests a series of analytical options to determine their applicability as tools to provide more rigorous species delimitation measures and consequently more defensible species assignments and identification of unknowns for biosecurity. Data from established DNA barcode datasets (COI), which are becoming increasingly considered for adoption in biosecurity, were used here as an example. The analytical approaches included the commonly used Kimura two-parameter (K2P) inter-species distance plus four more stringent measures of taxon distinctiveness, (1) Rosenberg’s reciprocal monophyly, (P(AB)),1 (2) Rodrigo’s (P(randomly distinct)),2 (3) genealogical sorting index, (gsi),3 and (4) General mixed Yule-coalescent (GMYC).4,5 For both insect datasets, a comparative analysis of the methods revealed that the K2P distance method does not capture the same level of species distinctiveness revealed by the other three measures; in B. tabaci there are more distinct groups than previously identified using the K2P distances and for L. dipsar far less variation is apparent within the predefined subspecies. A consensus for the results from P(AB), P(randomly distinct) and gsi offers greater statistical confidence as to where genetic limits

  10. A Simple Text File for Curing Rainbow Blindness

    NASA Technical Reports Server (NTRS)

    Krylo, Robert; Tomlin, Marilyn; Seager, Michael

    2008-01-01

    This slide presentation reviews the use of a simple text file to work with large, multi-component thermal models that present a post-processing challenge. This complexity is due to temperatures for many components, with varying requirements, need to be examined and that false color temperature maps, or rainbows, provide a qualitative assessment of results.

  11. Estimated agricultural pesticide use for Southeast Stream-Quality Assessment, 2014

    USGS Publications Warehouse

    Baker, Nancy T.

    2015-12-01

    This report provides estimates of annual agricultural use of 262 pesticide compounds for counties and selected watersheds in parts of eight southeastern States for 2014. Estimates of county- and watershed-level annual agricultural pesticide use are provided as downloadable, tab-delimited files for both EPest-high and EPest-low.

  12. Semi automatic indexing of PostScript files using Medical Text Indexer in medical education.

    PubMed

    Mollah, Shamim Ara; Cimino, Christopher

    2007-10-11

    At Albert Einstein College of Medicine a large part of online lecture materials contain PostScript files. As the collection grows it becomes essential to create a digital library to have easy access to relevant sections of the lecture material that is full-text indexed; to create this index it is necessary to extract all the text from the document files that constitute the originals of the lectures. In this study we present a semi automatic indexing method using robust technique for extracting text from PostScript files and National Library of Medicine's Medical Text Indexer (MTI) program for indexing the text. This model can be applied to other medical schools for indexing purposes.

  13. Rarity and Incomplete Sampling in DNA-Based Species Delimitation.

    PubMed

    Ahrens, Dirk; Fujisawa, Tomochika; Krammer, Hans-Joachim; Eberle, Jonas; Fabrizi, Silvia; Vogler, Alfried P

    2016-05-01

    DNA-based species delimitation may be compromised by limited sampling effort and species rarity, including "singleton" representatives of species, which hampers estimates of intra- versus interspecies evolutionary processes. In a case study of southern African chafers (beetles in the family Scarabaeidae), many species and subclades were poorly represented and 48.5% of species were singletons. Using cox1 sequences from >500 specimens and ∼100 species, the Generalized Mixed Yule Coalescent (GMYC) analysis as well as various other approaches for DNA-based species delimitation (Automatic Barcode Gap Discovery (ABGD), Poisson tree processes (PTP), Species Identifier, Statistical Parsimony), frequently produced poor results if analyzing a narrow target group only, but the performance improved when several subclades were combined. Hence, low sampling may be compensated for by "clade addition" of lineages outside of the focal group. Similar findings were obtained in reanalysis of published data sets of taxonomically poorly known species assemblages of insects from Madagascar. The low performance of undersampled trees is not due to high proportions of singletons per se, as shown in simulations (with 13%, 40% and 52% singletons). However, the GMYC method was highly sensitive to variable effective population size ([Formula: see text]), which was exacerbated by variable species abundances in the simulations. Hence, low sampling success and rarity of species affect the power of the GMYC method only if they reflect great differences in [Formula: see text] among species. Potential negative effects of skewed species abundances and prevalence of singletons are ultimately an issue about the variation in [Formula: see text] and the degree to which this is correlated with the census population size and sampling success. Clade addition beyond a limited study group can overcome poor sampling for the GMYC method in particular under variable [Formula: see text] This effect was less

  14. Maritime zones delimitation - Problems and solutions

    NASA Astrophysics Data System (ADS)

    Kastrisios, Christos; Tsoulos, Lysandros

    2018-05-01

    The delimitation of maritime zones and boundaries foreseen by the United Nations Convention on the Law of the Sea (UNCLOS) is a factor of economic growth, effective management of the coastal and ocean environment and the cornerstone for maritime spatial planning. Maritime zones and boundaries form the outermost limits of coastal states and their accurate delineation and cartographic portrayal is a matter of national priority. Although UNCLOS is a legal document, its implementation -at first place- is purely technical and requires -amongst others- theoretical and applied background on Geodesy, Cartography and Geographic Information Systems (GIS) for those involved. This paper provides a brief historical background of the evolution of the UNCLOS, presents the various concepts of the Convention and identifies the problems inherent in the maritime delimitation process. Furthermore, it presents solutions that will facilitate the cartographer's work in order to achieve unquestionable results. Through the paper it becomes evident that the role of the cartographer and the GIS expert is critical for the successful implementation of maritime delimitation.

  15. Total Petroleum Systems and Geologic Assessment of Oil and Gas Resources in the Powder River Basin Province, Wyoming and Montana

    USGS Publications Warehouse

    Anna, L.O.

    2009-01-01

    The U.S. Geological Survey completed an assessment of the undiscovered oil and gas potential of the Powder River Basin in 2006. The assessment of undiscovered oil and gas used the total petroleum system concept, which includes mapping the distribution of potential source rocks and known petroleum accumulations and determining the timing of petroleum generation and migration. Geologically based, it focuses on source and reservoir rock stratigraphy, timing of tectonic events and the configuration of resulting structures, formation of traps and seals, and burial history modeling. The total petroleum system is subdivided into assessment units based on similar geologic characteristics and accumulation and petroleum type. In chapter 1 of this report, five total petroleum systems, eight conventional assessment units, and three continuous assessment units were defined and the undiscovered oil and gas resources within each assessment unit quantitatively estimated. Chapter 2 describes data used in support of the process being applied by the U.S. Geological Survey (USGS) National Oil and Gas Assessment (NOGA) project. Digital tabular data used in this report and archival data that permit the user to perform further analyses are available elsewhere on this CD-ROM. Computers and software may import the data without transcription from the Portable Document Format files (.pdf files) of the text by the reader. Because of the number and variety of platforms and software available, graphical images are provided as .pdf files and tabular data are provided in a raw form as tab-delimited text files (.tab files).

  16. Tabs and Accordions

    EPA Pesticide Factsheets

    While tabs and accordions were once common across the Web, we no longer recommend their use on EPA pages. Research has demonstrated that the use of tabs and accordions on websites can cause a number of search, access, and usability problems.

  17. The mzTab Data Exchange Format: Communicating Mass-spectrometry-based Proteomics and Metabolomics Experimental Results to a Wider Audience*

    PubMed Central

    Griss, Johannes; Jones, Andrew R.; Sachsenberg, Timo; Walzer, Mathias; Gatto, Laurent; Hartler, Jürgen; Thallinger, Gerhard G.; Salek, Reza M.; Steinbeck, Christoph; Neuhauser, Nadin; Cox, Jürgen; Neumann, Steffen; Fan, Jun; Reisinger, Florian; Xu, Qing-Wei; del Toro, Noemi; Pérez-Riverol, Yasset; Ghali, Fawaz; Bandeira, Nuno; Xenarios, Ioannis; Kohlbacher, Oliver; Vizcaíno, Juan Antonio; Hermjakob, Henning

    2014-01-01

    The HUPO Proteomics Standards Initiative has developed several standardized data formats to facilitate data sharing in mass spectrometry (MS)-based proteomics. These allow researchers to report their complete results in a unified way. However, at present, there is no format to describe the final qualitative and quantitative results for proteomics and metabolomics experiments in a simple tabular format. Many downstream analysis use cases are only concerned with the final results of an experiment and require an easily accessible format, compatible with tools such as Microsoft Excel or R. We developed the mzTab file format for MS-based proteomics and metabolomics results to meet this need. mzTab is intended as a lightweight supplement to the existing standard XML-based file formats (mzML, mzIdentML, mzQuantML), providing a comprehensive summary, similar in concept to the supplemental material of a scientific publication. mzTab files can contain protein, peptide, and small molecule identifications together with experimental metadata and basic quantitative information. The format is not intended to store the complete experimental evidence but provides mechanisms to report results at different levels of detail. These range from a simple summary of the final results to a representation of the results including the experimental design. This format is ideally suited to make MS-based proteomics and metabolomics results available to a wider biological community outside the field of MS. Several software tools for proteomics and metabolomics have already adapted the format as an output format. The comprehensive mzTab specification document and extensive additional documentation can be found online. PMID:24980485

  18. The mzTab data exchange format: communicating mass-spectrometry-based proteomics and metabolomics experimental results to a wider audience.

    PubMed

    Griss, Johannes; Jones, Andrew R; Sachsenberg, Timo; Walzer, Mathias; Gatto, Laurent; Hartler, Jürgen; Thallinger, Gerhard G; Salek, Reza M; Steinbeck, Christoph; Neuhauser, Nadin; Cox, Jürgen; Neumann, Steffen; Fan, Jun; Reisinger, Florian; Xu, Qing-Wei; Del Toro, Noemi; Pérez-Riverol, Yasset; Ghali, Fawaz; Bandeira, Nuno; Xenarios, Ioannis; Kohlbacher, Oliver; Vizcaíno, Juan Antonio; Hermjakob, Henning

    2014-10-01

    The HUPO Proteomics Standards Initiative has developed several standardized data formats to facilitate data sharing in mass spectrometry (MS)-based proteomics. These allow researchers to report their complete results in a unified way. However, at present, there is no format to describe the final qualitative and quantitative results for proteomics and metabolomics experiments in a simple tabular format. Many downstream analysis use cases are only concerned with the final results of an experiment and require an easily accessible format, compatible with tools such as Microsoft Excel or R. We developed the mzTab file format for MS-based proteomics and metabolomics results to meet this need. mzTab is intended as a lightweight supplement to the existing standard XML-based file formats (mzML, mzIdentML, mzQuantML), providing a comprehensive summary, similar in concept to the supplemental material of a scientific publication. mzTab files can contain protein, peptide, and small molecule identifications together with experimental metadata and basic quantitative information. The format is not intended to store the complete experimental evidence but provides mechanisms to report results at different levels of detail. These range from a simple summary of the final results to a representation of the results including the experimental design. This format is ideally suited to make MS-based proteomics and metabolomics results available to a wider biological community outside the field of MS. Several software tools for proteomics and metabolomics have already adapted the format as an output format. The comprehensive mzTab specification document and extensive additional documentation can be found online. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

  19. Explorative visual analytics on interval-based genomic data and their metadata.

    PubMed

    Jalili, Vahid; Matteucci, Matteo; Masseroli, Marco; Ceri, Stefano

    2017-12-04

    With the wide-spreading of public repositories of NGS processed data, the availability of user-friendly and effective tools for data exploration, analysis and visualization is becoming very relevant. These tools enable interactive analytics, an exploratory approach for the seamless "sense-making" of data through on-the-fly integration of analysis and visualization phases, suggested not only for evaluating processing results, but also for designing and adapting NGS data analysis pipelines. This paper presents abstractions for supporting the early analysis of NGS processed data and their implementation in an associated tool, named GenoMetric Space Explorer (GeMSE). This tool serves the needs of the GenoMetric Query Language, an innovative cloud-based system for computing complex queries over heterogeneous processed data. It can also be used starting from any text files in standard BED, BroadPeak, NarrowPeak, GTF, or general tab-delimited format, containing numerical features of genomic regions; metadata can be provided as text files in tab-delimited attribute-value format. GeMSE allows interactive analytics, consisting of on-the-fly cycling among steps of data exploration, analysis and visualization that help biologists and bioinformaticians in making sense of heterogeneous genomic datasets. By means of an explorative interaction support, users can trace past activities and quickly recover their results, seamlessly going backward and forward in the analysis steps and comparative visualizations of heatmaps. GeMSE effective application and practical usefulness is demonstrated through significant use cases of biological interest. GeMSE is available at http://www.bioinformatics.deib.polimi.it/GeMSE/ , and its source code is available at https://github.com/Genometric/GeMSE under GPLv3 open-source license.

  20. Wind-Tunnel Investigation of the Effect of Tab Balance on Tab and Control-Surface Characteristics

    NASA Technical Reports Server (NTRS)

    Brewer, Jack D; Queijo, M J

    1947-01-01

    An investigation was conducted to furnish data on the effect of tab balance on tab and control-surface characteristics. The airfoil tested had a modified NACA 65(1)-012 contour with a plain flap having a chord equal to 25 percent of the wing chord and with a tab having a chord equal to 25 percent of the flap chord and having several nose shapes and overhang lengths. The results of the investigation indicated that, in general, tab balance affected tab hinge-moment characteristics in much the same manner that flap balance affects flap hinge-moment characteristics. A moderate amount of tab balance did not seem to have any adverse effect on flap hinge-moment characteristics.

  1. Do DNA barcoding delimitation methods affect our view of stream biodiversity?

    EPA Science Inventory

    How we delimit molecular operational taxonomic units (MOTUs) is an important aspect in the use of DNA barcoding for bioassessment. Four delimitation methods were examined to gain an understanding of their relative strengths at organizing data from 5300 specimens collected during ...

  2. Creating and indexing teaching files from free-text patient reports.

    PubMed Central

    Johnson, D. B.; Chu, W. W.; Dionisio, J. D.; Taira, R. K.; Kangarloo, H.

    1999-01-01

    Teaching files based on real patient data can enhance the education of students, staff and other colleagues. Although information retrieval system can index free-text documents using keywords, these systems do not work well where content bearing terms (e.g., anatomy descriptions) frequently appears. This paper describes a system that uses multi-word indexing terms to provide access to free-text patient reports. The utilization of multi-word indexing allows better modeling of the content of medical reports, thus improving retrieval performance. The method used to select indexing terms as well as early evaluation of retrieval performance is discussed. PMID:10566473

  3. 14 CFR 23.409 - Tabs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES Structure Control Surface and System Loads § 23.409 Tabs. Control surface tabs must be designed for the most severe combination of airspeed and tab deflection likely to be obtained within the flight envelope for any usable loading condition. ...

  4. ORFer--retrieval of protein sequences and open reading frames from GenBank and storage into relational databases or text files.

    PubMed

    Büssow, Konrad; Hoffmann, Steve; Sievert, Volker

    2002-12-19

    Functional genomics involves the parallel experimentation with large sets of proteins. This requires management of large sets of open reading frames as a prerequisite of the cloning and recombinant expression of these proteins. A Java program was developed for retrieval of protein and nucleic acid sequences and annotations from NCBI GenBank, using the XML sequence format. Annotations retrieved by ORFer include sequence name, organism and also the completeness of the sequence. The program has a graphical user interface, although it can be used in a non-interactive mode. For protein sequences, the program also extracts the open reading frame sequence, if available, and checks its correct translation. ORFer accepts user input in the form of single or lists of GenBank GI identifiers or accession numbers. It can be used to extract complete sets of open reading frames and protein sequences from any kind of GenBank sequence entry, including complete genomes or chromosomes. Sequences are either stored with their features in a relational database or can be exported as text files in Fasta or tabulator delimited format. The ORFer program is freely available at http://www.proteinstrukturfabrik.de/orfer. The ORFer program allows for fast retrieval of DNA sequences, protein sequences and their open reading frames and sequence annotations from GenBank. Furthermore, storage of sequences and features in a relational database is supported. Such a database can supplement a laboratory information system (LIMS) with appropriate sequence information.

  5. Duplex tab exhaust nozzle

    NASA Technical Reports Server (NTRS)

    Gutmark, Ephraim Jeff (Inventor); Martens, Steven (nmn) (Inventor)

    2012-01-01

    An exhaust nozzle includes a conical duct terminating in an annular outlet. A row of vortex generating duplex tabs are mounted in the outlet. The tabs have compound radial and circumferential aft inclination inside the outlet for generating streamwise vortices for attenuating exhaust noise while reducing performance loss.

  6. Delimitation of volcanic edifices for landscape characterization and planning

    NASA Astrophysics Data System (ADS)

    Melis, Maria Teresa; Mundula, Filippo; Dessì, Francesco; Danila Patta, Elisabetta; Funedda, Antonio; Cioni, Raffaello

    2014-05-01

    The European Landscape Convention, recently adopted in Italy, indicates specific landforms to be selected as special protected sites. Active and inactive volcanic edifices, defined as the products of evolution of aggradational (lava effusion, pyroclastic deposition, magma intrusion) and degradational processes (erosion, deformation, gravitative phenomena), are one of the specific landforms to be protected. In order to protect these sites, management and planning measures are to be defined and shared with the local communities. In the framework of the Regional Landscape Management Plan of Sardinia (Italy), a detailed study aimed at identifying and delimiting Cenozoic volcanic edifices was performed. The large geological and morphological variability of the volcanic edifices of Sardinia in terms of type, dimension, age, integrity (a measure of the wholeness and intactnes of the volcanic edifice), geology and paleomorphology of the substrate, does not allow the definition of an automatic procedure for extracting the boundaries to delimit the volcanic edifices. In addition, quantitative geomorphological studies in the field of volcanology are confined to specific volcano types, and landscape literature does not suggest any universal criteria for delimiting volcanic edifices, except for the use of the concave breaks in slope at their base (Euillades et al., Computers and Geosciences, 2013). As this simple criterion can be unequivocally applied only in the ideal case of symmetric cones or domes built up on a planar surface, we developed a multidisciplinary methodology based on the integrated analysis of geological, geomorphological and morphometrical data of each edifice. The process of selection and delimitation of the volcanic edifices is the result of the following steps: i) a literature based delimitation of the volcanic edifice; ii) a preliminary delimitation through photo-interpretation and the use of geological criteria; and iii) a final refinement based on the

  7. Species delimitation using Bayes factors: simulations and application to the Sceloporus scalaris species group (Squamata: Phrynosomatidae).

    PubMed

    Grummer, Jared A; Bryson, Robert W; Reeder, Tod W

    2014-03-01

    Current molecular methods of species delimitation are limited by the types of species delimitation models and scenarios that can be tested. Bayes factors allow for more flexibility in testing non-nested species delimitation models and hypotheses of individual assignment to alternative lineages. Here, we examined the efficacy of Bayes factors in delimiting species through simulations and empirical data from the Sceloporus scalaris species group. Marginal-likelihood scores of competing species delimitation models, from which Bayes factor values were compared, were estimated with four different methods: harmonic mean estimation (HME), smoothed harmonic mean estimation (sHME), path-sampling/thermodynamic integration (PS), and stepping-stone (SS) analysis. We also performed model selection using a posterior simulation-based analog of the Akaike information criterion through Markov chain Monte Carlo analysis (AICM). Bayes factor species delimitation results from the empirical data were then compared with results from the reversible-jump MCMC (rjMCMC) coalescent-based species delimitation method Bayesian Phylogenetics and Phylogeography (BP&P). Simulation results show that HME and sHME perform poorly compared with PS and SS marginal-likelihood estimators when identifying the true species delimitation model. Furthermore, Bayes factor delimitation (BFD) of species showed improved performance when species limits are tested by reassigning individuals between species, as opposed to either lumping or splitting lineages. In the empirical data, BFD through PS and SS analyses, as well as the rjMCMC method, each provide support for the recognition of all scalaris group taxa as independent evolutionary lineages. Bayes factor species delimitation and BP&P also support the recognition of three previously undescribed lineages. In both simulated and empirical data sets, harmonic and smoothed harmonic mean marginal-likelihood estimators provided much higher marginal-likelihood estimates

  8. Automatic Match between Delimitation Line and Real Terrain Based on Least-Cost Path Analysis

    NASA Astrophysics Data System (ADS)

    Feng, C. Q.; Jiang, N.; Zhang, X. N.; Ma, J.

    2013-11-01

    Nowadays, during the international negotiation on separating dispute areas, manual adjusting is lonely applied to the match between delimitation line and real terrain, which not only consumes much time and great labor force, but also cannot ensure high precision. Concerning that, the paper mainly explores automatic match between them and study its general solution based on Least -Cost Path Analysis. First, under the guidelines of delimitation laws, the cost layer is acquired through special disposals of delimitation line and terrain features line. Second, a new delimitation line gets constructed with the help of Least-Cost Path Analysis. Third, the whole automatic match model is built via Module Builder in order to share and reuse it. Finally, the result of automatic match is analyzed from many different aspects, including delimitation laws, two-sided benefits and so on. Consequently, a conclusion is made that the method of automatic match is feasible and effective.

  9. 5 CFR 1201.128 - Filing complaint; serving documents on parties.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Corrective Actions § 1201.128 Filing complaint; serving documents on parties. (a) Place of filing. A Special... copies of the complaint, together with numbered and tabbed exhibits or attachments, if any, and a...

  10. 5 CFR 1201.128 - Filing complaint; serving documents on parties.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Corrective Actions § 1201.128 Filing complaint; serving documents on parties. (a) Place of filing. A Special... copies of the complaint, together with numbered and tabbed exhibits or attachments, if any, and a...

  11. 5 CFR 1201.122 - Filing complaint; serving documents on parties.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Disciplinary Actions § 1201.122 Filing complaint; serving documents on parties. (a) Place of filing. A Special... tabbed exhibits or attachments, if any, and a certificate of service listing each party or the party's...

  12. Application of Balancing Tabs to Ailerons

    NASA Technical Reports Server (NTRS)

    Sears, Richard I.

    1942-01-01

    Analysis was made to determine characteristics required of a balancing-tab system for ailerons in order to reduce aileron stick forces to any desired magnitude. Series of calculations based on section data were made to determine balancing-tab systems of various chord tabs and ailerons that will give, for a particular airplane, zero rate of aileron hinge moment with aileron deflection and yet will produce same maximum rate of roll as a plain unbalanced 15-percent chord aileron of same span. Effects of rolling velocity and of forces in tab link on aileron hinge moments have been included.

  13. 14 CFR 25.409 - Tabs.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Tabs. 25.409 Section 25.409 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS... for the airplane as a whole), when the effect of the tab is opposed by pilot effort forces up to those...

  14. 14 CFR 25.409 - Tabs.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Tabs. 25.409 Section 25.409 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS... for the airplane as a whole), when the effect of the tab is opposed by pilot effort forces up to those...

  15. 14 CFR 25.409 - Tabs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Tabs. 25.409 Section 25.409 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS... for the airplane as a whole), when the effect of the tab is opposed by pilot effort forces up to those...

  16. 14 CFR 25.409 - Tabs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Tabs. 25.409 Section 25.409 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS... for the airplane as a whole), when the effect of the tab is opposed by pilot effort forces up to those...

  17. 14 CFR 25.409 - Tabs.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Tabs. 25.409 Section 25.409 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS... for the airplane as a whole), when the effect of the tab is opposed by pilot effort forces up to those...

  18. Lift-Enhancing Tabs on Multielement Airfoils

    NASA Technical Reports Server (NTRS)

    Ross, James C.; Storms, Bruce L.; Carrannanto, Paul G.

    1995-01-01

    The use of flat-plate tabs (similar to Gurney flaps) to enhance the lift of multielement airfoils is extended here by placing them on the pressure side and near the trailing edge of the main element rather than just on the furthest downstream wing element. The tabs studied range in height from 0.125 to 1.25% of the airfoil reference chord. In practice, such tabs would be retracted when the high-lift system is stowed. The effectiveness of the concept was demonstrated experimentally and computationally on a two-dimensional NACA 63(sub 2)-215 Mod B airfoil with a single-slotted, 30%-chord flap. Both the experiments and computations showed that the tabs significantly increase the lift at a given angle of attack and the maximum lift coefficient of the airfoil. The computational results showed that the increased lift was a result of additional turning of the flow by the tab that reduced or eliminated now separation on the flap. The best configuration tested, a 0.5%-chord tab placed 0.5% chord upstream of the trailing edge of the main element, increased the maximum lift coefficient of the airfoil by 12% and the maximum lift-to-drag ratio by 40%.

  19. Putting the Biological Species Concept to the Test: Using Mating Networks to Delimit Species

    PubMed Central

    Lagache, Lélia; Leger, Jean-Benoist; Daudin, Jean-Jacques; Petit, Rémy J.; Vacher, Corinne

    2013-01-01

    Although interfertility is the key criterion upon which Mayr’s biological species concept is based, it has never been applied directly to delimit species under natural conditions. Our study fills this gap. We used the interfertility criterion to delimit two closely related oak species in a forest stand by analyzing the network of natural mating events between individuals. The results reveal two groups of interfertile individuals connected by only few mating events. These two groups were largely congruent with those determined using other criteria (morphological similarity, genotypic similarity and individual relatedness). Our study, therefore, shows that the analysis of mating networks is an effective method to delimit species based on the interfertility criterion, provided that adequate network data can be assembled. Our study also shows that although species boundaries are highly congruent across methods of species delimitation, they are not exactly the same. Most of the differences stem from assignment of individuals to an intermediate category. The discrepancies between methods may reflect a biological reality. Indeed, the interfertility criterion is an environment-dependant criterion as species abundances typically affect rates of hybridization under natural conditions. Thus, the methods of species delimitation based on the interfertility criterion are expected to give results slightly different from those based on environment-independent criteria (such as the genotypic similarity criteria). However, whatever the criterion chosen, the challenge we face when delimiting species is to summarize continuous but non-uniform variations in biological diversity. The grade of membership model that we use in this study appears as an appropriate tool. PMID:23818990

  20. Lift enhancing tabs for airfoils

    NASA Technical Reports Server (NTRS)

    Ross, James C. (Inventor)

    1994-01-01

    A tab deployable from the trailing edge of a main airfoil element forces flow onto a following airfoil element, such as a flap, to keep the flow attached and thus enhance lift. For aircraft wings with high lift systems that include leading edge slats, the slats may also be provided with tabs to turn the flow onto the following main element.

  1. Some utilities to help produce Rich Text Files from Stata.

    PubMed

    Gillman, Matthew S

    Producing RTF files from Stata can be difficult and somewhat cryptic. Utilities are introduced to simplify this process; one builds up a table row-by-row, another inserts a PNG image file into an RTF document, and the others start and finish the RTF document.

  2. 14 CFR 25.407 - Trim tab effects.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Trim tab effects. 25.407 Section 25.407... STANDARDS: TRANSPORT CATEGORY AIRPLANES Structure Control Surface and System Loads § 25.407 Trim tab effects. The effects of trim tabs on the control surface design conditions must be accounted for only where the...

  3. 14 CFR 25.407 - Trim tab effects.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Trim tab effects. 25.407 Section 25.407... STANDARDS: TRANSPORT CATEGORY AIRPLANES Structure Control Surface and System Loads § 25.407 Trim tab effects. The effects of trim tabs on the control surface design conditions must be accounted for only where the...

  4. Correlation analysis on real-time tab-delimited network monitoring data

    DOE PAGES

    Pan, Aditya; Majumdar, Jahin; Bansal, Abhay; ...

    2016-01-01

    End-End performance monitoring in the Internet, also called PingER is a part of SLAC National Accelerator Laboratory’s research project. It was created to answer the growing need to monitor network both to analyze current performance and to designate resources to optimize execution between research centers, and the universities and institutes co-operating on present and future operations. The monitoring support reflects the broad geographical area of the collaborations and requires a comprehensive number of research and financial channels. The data architecture retrieval and methodology of the interpretation have emerged over numerous years. Analyzing this data is the main challenge due tomore » its high volume. Finally, by using correlation analysis, we can make crucial conclusions about how the network data affects the performance of the hosts and how it depends from countries to countries.« less

  5. 14 CFR 23.407 - Trim tab effects.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Trim tab effects. 23.407 Section 23.407... Loads § 23.407 Trim tab effects. The effects of trim tabs on the control surface design conditions must... deflections must correspond to the maximum degree of “out of trim” expected at the speed for the condition...

  6. 14 CFR 23.407 - Trim tab effects.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Trim tab effects. 23.407 Section 23.407... Loads § 23.407 Trim tab effects. The effects of trim tabs on the control surface design conditions must... deflections must correspond to the maximum degree of “out of trim” expected at the speed for the condition...

  7. A study on the development of automatic economic profit and loss calculation system for maritime boundary delimitation

    NASA Astrophysics Data System (ADS)

    Kwak, G.; Kim, K.; Park, Y.

    2014-02-01

    As the maritime boundary delimitation is important for the purpose of securing marine resources, in addition to the aspect of maritime security, interest in maritime boundary delimitation to help national benefits are increasing over the world. In Korea, the importance of maritime boundary delimitation with the neighbouring countries is also increasing in practice. The quantity of obtainable marine resources depending on maritime boundary acts as an important factor for maritime boundary delimitation. Accordingly, a study is required to calculate quantity of our obtainable marine resources depending on maritime boundary delimitation. This study intends to calculate obtainable marine resources depending on various maritime boundary scenarios insisted by several countries. It mainly aims at developing a GIS-based automation system to be utilized for decision making of the maritime boundary delimitation. For this target, it has designed a module using spatial analysis technique to automatically calculate profit and loss waters area of each country upon maritime boundary and another module to estimate economic profits and losses obtained by each country using the calculated waters area and pricing information of the marine resources. By linking both the designed modules, it has implemented an automatic economic profit and loss calculation system for the GIS-based maritime boundary delimitation. The system developed from this study automatically calculate quantity of the obtainable marine resources of a country for the maritime boundary to be added and created in the future. Thus, it is expected to support decision making for the maritime boundary negotiators.

  8. Some utilities to help produce Rich Text Files from Stata

    PubMed Central

    Gillman, Matthew S.

    2018-01-01

    Producing RTF files from Stata can be difficult and somewhat cryptic. Utilities are introduced to simplify this process; one builds up a table row-by-row, another inserts a PNG image file into an RTF document, and the others start and finish the RTF document. PMID:29731697

  9. How do societies and "corporate" groups delimit themselves? A puzzle common to social and medical anthropology.

    PubMed

    Zempléni, A

    1990-06-01

    Classic anthropological theories define the first but neglect the second condition of social life. When they assume that the universal effect of the incest taboo is the opening of the consanguinial groups to the others, to exchange, they do not explain the closure of their sphere of reciprocity, i.e., the delimitation of the society. Hence the question: How, by which means, are stateless societies delimited or do they delimit themselves? Among the Senoufo of Ivory Coast (Nafara), one of the main acts of male initiation ceremonies--to the Poro, which is the very basis of the Senoufo's ethnic identity--is a ritual intercourse between the neophytes and their symbolic mother who has just given birth to them. This rite materializes the initiatic axiom: Senoufo men reproduce themselves by incest. In this case, the prescription of ritual incest is a means by which the society "closes" the field of reciprocity "opened" by the prohibition of actual incest. The return of the forbidden--at the heart of the institution which reproduces its identity--is the basic principle of the ritual delimitation of this society. Despite appearances, the delimitation of the so-called "corporate groups"--for example, an African lineage--is neither more "natural" nor more jural than that of the society which contains them. The limits of these groups are traced and retraced notably in the course of traditional "therapies" and by means of etiological entities which share several common, distinctive properties. (1) They cannot operate outside of the group delimited by them. (2) They are polyvalent and their effects are permutable from one group-member to another. (3) They act periodically: they have to dismantle the group periodically from the inside in order to be able to delimit it constantly from the outside. This phenomenon of spatio-temporal inversion (inside-outside; periodic-continuous), observable in any process of ritual delimitation, deserves our attention insofar as its closer analysis

  10. 12 CFR Appendix C to Part 360 - Deposit File Structure

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... tax identification number. Possible values are: • S = Social Security Number. • T = Federal Tax... or do not apply, a null value in the appropriate field should be indicated. The file will be in a tab... complete its insurance determination process, it may add this information to the end of this data file...

  11. 12 CFR Appendix C to Part 360 - Deposit File Structure

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... tax identification number. Possible values are: • S = Social Security Number. • T = Federal Tax... or do not apply, a null value in the appropriate field should be indicated. The file will be in a tab... complete its insurance determination process, it may add this information to the end of this data file...

  12. 12 CFR Appendix C to Part 360 - Deposit File Structure

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... tax identification number. Possible values are: • S = Social Security Number. • T = Federal Tax... or do not apply, a null value in the appropriate field should be indicated. The file will be in a tab... complete its insurance determination process, it may add this information to the end of this data file...

  13. Investigation of the Vortex Tab. M.S. Thesis

    NASA Technical Reports Server (NTRS)

    Hoffler, K. D.

    1985-01-01

    An investigation was made into the drag reduction capability of vortex tabs on delta wing vortex flaps. The vortex tab is an up-deflected leading edge portion of the vortex flap. Tab deflection augments vortex suction on the flap, thus improving its thrust, but the tab itself is drag producing. Whether a net improvement in the drag reduction can be obtained with vortex tabs, in comparison with plane vortex flaps of the same total area, was the objective of this investigation. Wind tunnel tests were conducted on two models, and analytical studies were performed on one of them using a free vortex sheet theory.

  14. Experimental Investigation of a Preloaded Spring-tab Flutter Model

    NASA Technical Reports Server (NTRS)

    Smith, N H; Clevenson, S A; Barmby, J G

    1947-01-01

    An experimental investigation was made of a preloaded spring-tab flutter model to determine the effects on flutter speed of aspect ratio, tab frequency, and preloaded spring constant. The rudder was mass-balanced, and the flutter mode studied was essentially one of three degrees of freedom (fin bending coupled with rudder and tab oscillations). Inasmuch as the spring was preloaded, the tab-spring system was a nonlinear one. Frequency of the tab was the most significant parameter in this study, and an increase in flutter speed with increasing frequency is indicated. At a given frequency, the tab of high aspect ratio is shown to have a slightly lower flutter speed than the one of low aspect ratio. Because the frequency of the preloaded spring tab was found to vary radically with amplitude, the flutter speed decreased with increase in initial displacement of the tab.

  15. Delimiting cryptic pathogen species causing apple Valsa canker with multilocus data

    PubMed Central

    Wang, Xuli; Zang, Rui; Yin, Zhiyuan; Kang, Zhensheng; Huang, Lili

    2014-01-01

    Fungal diseases are posing tremendous threats to global economy and food safety. Among them, Valsa canker, caused by fungi of Valsa and their Cytospora anamorphs, has been a serious threat to fruit and forest trees and is one of the most destructive diseases of apple in East Asia, particularly. Accurate and robust delimitation of pathogen species is not only essential for the development of effective disease control programs, but also will advance our understanding of the emergence of plant diseases. However, species delimitation is especially difficult in Valsa because of the high variability of morphological traits and in many cases the lack of the teleomorph. In this study, we delimitated species boundary for pathogens causing apple Valsa canker with a multifaceted approach. Based on three independent loci, the internal transcribed spacer (ITS), β-tubulin (Btu), and translation elongation factor-1 alpha (EF1α), we inferred gene trees with both maximum likelihood and Bayesian methods, estimated species tree with Bayesian multispecies coalescent approaches, and validated species tree with Bayesian species delimitation. Through divergence time estimation and ancestral host reconstruction, we tested the possible underlying mechanisms for fungal speciation and host-range change. Our results proved that two varieties of the former morphological species V. mali represented two distinct species, V. mali and V. pyri, which diverged about 5 million years ago, much later than the divergence of their preferred hosts, excluding a scenario of fungi–host co-speciation. The marked different thermal preferences and contrasting pathogenicity in cross-inoculation suggest ecological divergences between the two species. Apple was the most likely ancestral host for both V. mali and V. pyri. Host-range expansion led to the occurrence of V. pyri on both pear and apple. Our results also represent an example in which ITS data might underestimate species diversity. PMID:24834333

  16. Application of spring tabs to elevator controls

    NASA Technical Reports Server (NTRS)

    Phillips, William H

    1944-01-01

    Equations are presented for calculating the stick-force characteristics obtained with a spring-tab type of elevator control. The main problems encountered in the design of a satisfactory elevator spring tab are to provide stick forces in the desired range, to maintain the force per g sufficiently constant throughout the speed range, to avoid undesirable "feel" of the control in ground handling or in flight at low airspeeds, and to prevent flutter. Examples are presented to show the design features of spring tabs required to solve these problems for airplanes of various sizes.

  17. Species delimitation: A case study in a problematic ant taxon

    USDA-ARS?s Scientific Manuscript database

    Species delimitation has been invigorated as a discipline in systematics by an influx of new character sets, analytical methods, and conceptual advances. We use genetic data from 68 markers, combined with distributional, bioclimatic, and coloration information, to distinguish evolutionarily indepe...

  18. Supersonic Aerodynamic Characteristics of Blunt Body Trim Tab Configurations

    NASA Technical Reports Server (NTRS)

    Korzun, Ashley M.; Murphy, Kelly J.; Edquist, Karl T.

    2013-01-01

    Trim tabs are aerodynamic control surfaces that can allow an entry vehicle to meet aerodynamic performance requirements while reducing or eliminating the use of ballast mass and providing a capability to modulate the lift-to-drag ratio during entry. Force and moment data were obtained on 38 unique, blunt body trim tab configurations in the NASA Langley Research Center Unitary Plan Wind Tunnel. The data were used to parametrically assess the supersonic aerodynamic performance of trim tabs and to understand the influence of tab area, cant angle, and aspect ratio. Across the range of conditions tested (Mach numbers of 2.5, 3.5, and 4.5; angles of attack from -4deg to +20deg; angles of sideslip from 0deg to +8deg), the effects of varying tab area and tab cant angle were found to be much more significant than effects from varying tab aspect ratio. Aerodynamic characteristics exhibited variation with Mach number and forebody geometry over the range of conditions tested. Overall, the results demonstrate that trim tabs are a viable approach to satisfy aerodynamic performance requirements of blunt body entry vehicles with minimal ballast mass. For a 70deg sphere-cone, a tab with 3% area of the forebody and canted approximately 35deg with no ballast mass was found to give the same trim aerodynamics as a baseline model with ballast mass that was 5% of the total entry mass.

  19. Phylogenetic species delimitation for crayfishes of the genus Pacifastacus.

    PubMed

    Larson, Eric R; Castelin, Magalie; Williams, Bronwyn W; Olden, Julian D; Abbott, Cathryn L

    2016-01-01

    Molecular genetic approaches are playing an increasing role in conservation science by identifying biodiversity that may not be evident by morphology-based taxonomy and systematics. So-called cryptic species are particularly prevalent in freshwater environments, where isolation of dispersal-limited species, such as crayfishes, within dendritic river networks often gives rise to high intra- and inter-specific genetic divergence. We apply here a multi-gene molecular approach to investigate relationships among extant species of the crayfish genus Pacifastacus, representing the first comprehensive phylogenetic study of this taxonomic group. Importantly, Pacifastacus includes both the widely invasive signal crayfish Pacifastacus leniusculus, as well as several species of conservation concern like the Shasta crayfish Pacifastacus fortis. Our analysis used 83 individuals sampled across the four extant Pacifastacus species (omitting the extinct Pacifastacus nigrescens), representing the known taxonomic diversity and geographic distributions within this genus as comprehensively as possible. We reconstructed phylogenetic trees from mitochondrial (16S, COI) and nuclear genes (GAPDH), both separately and using a combined or concatenated dataset, and performed several species delimitation analyses (PTP, ABGD, GMYC) on the COI phylogeny to propose Primary Species Hypotheses (PSHs) within the genus. All phylogenies recovered the genus Pacifastacus as monophyletic, within which we identified a range of six to 21 PSHs; more abundant PSHs delimitations from GMYC and ABGD were always nested within PSHs delimited by the more conservative PTP method. Pacifastacus leniusculus included the majority of PSHs and was not monophyletic relative to the other Pacifastacus species considered. Several of these highly distinct P. leniusculus PSHs likely require urgent conservation attention. Our results identify research needs and conservation priorities for Pacifastacus crayfishes in western

  20. Impact of tree priors in species delimitation and phylogenetics of the genus Oligoryzomys (Rodentia: Cricetidae).

    PubMed

    da Cruz, Marcos de O R; Weksler, Marcelo

    2018-02-01

    The use of genetic data and tree-based algorithms to delimit evolutionary lineages is becoming an important practice in taxonomic identification, especially in morphologically cryptic groups. The effects of different phylogenetic and/or coalescent models in the analyses of species delimitation, however, are not clear. In this paper, we assess the impact of different evolutionary priors in phylogenetic estimation, species delimitation, and molecular dating of the genus Oligoryzomys (Mammalia: Rodentia), a group with complex taxonomy and morphological cryptic species. Phylogenetic and coalescent analyses included 20 of the 24 recognized species of the genus, comprising of 416 Cytochrome b sequences, 26 Cytochrome c oxidase I sequences, and 27 Beta-Fibrinogen Intron 7 sequences. For species delimitation, we employed the General Mixed Yule Coalescent (GMYC) and Bayesian Poisson tree processes (bPTP) analyses, and contrasted 4 genealogical and phylogenetic models: Pure-birth (Yule), Constant Population Size Coalescent, Multiple Species Coalescent, and a mixed Yule-Coalescent model. GMYC analyses of trees from different genealogical models resulted in similar species delimitation and phylogenetic relationships, with incongruence restricted to areas of poor nodal support. bPTP results, however, significantly differed from GMYC for 5 taxa. Oligoryzomys early diversification was estimated to have occurred in the Early Pleistocene, between 0.7 and 2.6 MYA. The mixed Yule-Coalescent model, however, recovered younger dating estimates for Oligoryzomys diversification, and for the threshold for the speciation-coalescent horizon in GMYC. Eight of the 20 included Oligoryzomys species were identified as having two or more independent evolutionary units, indicating that current taxonomy of Oligoryzomys is still unsettled. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. A Tool that Uses the SAS (registered trademark) PRX Functions to Fix Delimited Text Files

    DTIC Science & Technology

    2015-07-07

    service names are registered trademarks or trademarks of SAS Institute Inc. in the USA and other countries...indicates USA registration. Other brand and product names are trademarks of their respective companies. 20 Distribution A: Approved for public release; distribution is unlimited. Case Number: 88ABW-2015-1635, 31 Mar 2015 ...including suggestions for reducing this burden to Department of Defense, Washington Headquarters Services , Directorate for Information

  2. Evaluating multiple criteria for species delimitation: an empirical example using Hawaiian palms (Arecaceae: Pritchardia)

    PubMed Central

    2012-01-01

    Background Robust species delimitations are fundamental for conservation, evolutionary, and systematic studies, but they can be difficult to estimate, particularly in rapid and recent radiations. The consensus that species concepts aim to identify evolutionarily distinct lineages is clear, but the criteria used to distinguish evolutionary lineages differ based on the perceived importance of the various characteristics of evolving populations. We examined three different species-delimitation criteria (monophyly, absence of genetic intermediates, and diagnosability) to determine whether currently recognized species of Hawaiian Pritchardia are distinct lineages. Results Data from plastid and nuclear genes, microsatellite loci, and morphological characters resulted in various levels of lineage subdivision that were likely caused by differing evolutionary rates between data sources. Additionally, taxonomic entities may be confounded because of the effects of incomplete lineage sorting and/or gene flow. A coalescent species tree was largely congruent with the simultaneous analysis, consistent with the idea that incomplete lineage sorting did not mislead our results. Furthermore, gene flow among populations of sympatric lineages likely explains the admixture and lack of resolution between those groups. Conclusions Delimiting Hawaiian Pritchardia species remains difficult but the ability to understand the influence of the evolutionary processes of incomplete lineage sorting and hybridization allow for mechanisms driving species diversity to be inferred. These processes likely extend to speciation in other Hawaiian angiosperm groups and the biota in general and must be explicitly accounted for in species delimitation. PMID:22353848

  3. 1984 TABS Final Report.

    ERIC Educational Resources Information Center

    Austin Independent School District, TX. Office of Research and Evaluation.

    This report presents Austin Independent School District 1984 test results on the Texas Assessment of Basics Skills (TABS). It was administered to all third, fifth and ninth grade students and to high school students not meeting ninth grade state-set mastery criteria, the minimum competency requirement for graduation. Results are presented as…

  4. Adhesive-Bonded Tab Attaches Thermocouples to Titanium

    NASA Technical Reports Server (NTRS)

    Cook, C. F.

    1982-01-01

    Mechanical strength of titanium-alloy structures that support thermocouples is preserved by first spotwelding thermocouples to titanium tabs and then attaching tabs to titanium with a thermosetting adhesive. In contrast to spot welding, a technique previously used for thermocouples, fatigue strength of the titanium is unaffected by adhesive bonding. Technique is also gentler than soldering or attaching thermocouples with a tap screw.

  5. ListingAnalyst: A program for analyzing the main output file from MODFLOW

    USGS Publications Warehouse

    Winston, Richard B.; Paulinski, Scott

    2014-01-01

    ListingAnalyst is a Windows® program for viewing the main output file from MODFLOW-2005, MODFLOW-NWT, or MODFLOW-LGR. It organizes and displays large files quickly without using excessive memory. The sections and subsections of the file are displayed in a tree-view control, which allows the user to navigate quickly to desired locations in the files. ListingAnalyst gathers error and warning messages scattered throughout the main output file and displays them all together in an error and a warning tab. A grid view displays tables in a readable format and allows the user to copy the table into a spreadsheet. The user can also search the file for terms of interest.

  6. Delimitation of air space and outer space - Is such a boundary needed now?

    NASA Technical Reports Server (NTRS)

    Hosenball, S. N.

    1983-01-01

    A discussion is presented of the question of establishing a boundary between air space and outer space. Four theories and approaches for establishing a delimitation between air space and outer space are examined. Spatial approaches include demarcation based on the division of the atmosphere into layers, demarcation based on aerodynamic characteristics of flight instrumentalities (von Karman Line), demarcation according to the lowest perigee of an orbiting satellite, and demarcation based upon the earth's gravitational effects. The functionalist approach is based on the delimitation or definition of the air space/outer space regime by the purpose and activities for which an object is designed in air space or outer space. The arbitrarist approach is supported by those who wish to draw an arbitrary line between air space and outer space. It is proposed that a pragmatist approach will be more useful than the other three approaches. The pragmatist approach advocates not establishing a boundary between air space and outer space at the present time or in the immediate future. It is argued that there are at present no serious problems that can be resolved by the definition/delimitation of air space and outer space.

  7. Mixing Enhancement by Tabs in Round Supersonic Jets

    NASA Technical Reports Server (NTRS)

    Seiner, John M.; Grosch, C. E.

    1998-01-01

    The objective of this study was to analyze jet plume mass flow entrainment rates associated with the introduction of counter-rotating streamwise vorticity by prism shaped devices (tabs) located at the lip of the nozzle. We have examined the resulting mixing process through coordinated experimental tests and numerical simulations of the supersonic flow from a model axisymmetric nozzle. In the numerical simulations, the total induced vorticity was held constant while varying the distribution of counter-rotating vorticity around the nozzle lip training edge. In the experiment, the number of tabs applied was varied while holding the total projected area constant. Evaluations were also conducted on initial vortex strength. The results of this work show that the initial growth rate of the jet shear layer is increasingly enhanced as more tabs are added, but that the lowest tab count results in the largest entrained mass flow. The numerical simulations confirm these results.

  8. TAB interconnects for space concentrator solar cell arrays

    NASA Technical Reports Server (NTRS)

    Avery, J.; Bauman, J. S.; Gallagher, P.; Yerkes, J. W.

    1993-01-01

    The Boeing Company has evaluated the use of Tape Automated Bonding (TAB) and Surface Mount Technology (SMT) for a highly reliable, low cost interconnect for concentrator solar cell arrays. TAB and SMT are currently used in the electronics industry for chip interconnects and printed circuit board assembly. TAB tape consists of sixty-four 3-mil/1-oz tin-plated copper leads on 8-mil centers. The leads are thermocompression gang bonded to GaAs concentrator solar cell with silver contacts. This bond, known as an Inner Lead Bond (ILB), allows for pretesting and sorting capability via nondestruct wire bond pull and flash testing. Destructive wire pull tests resulted in preferred mid-span failures. Improvements in fill factor were attributed to decreased contact resistance on TAB bonded cells. Preliminary thermal cycling and aging tests were shown excellent bond strength and metallurgical results. Auger scans of bond sites reveals an Ag-Cu-Tin composition. Improper bonds are identified through flash testing as a performance degradation. On going testing of cells are underway at Lewis Research Center. SMT techniques are utilized to excise and form TAB leads post ILB. The formed leads' shape isolates thermal mismatches between the cells and the flex circuit they are mounted on. TABed cells are picked and placed with a gantry x-y-z positioning system with pattern recognition. Adhesives are selected to avoid thermal expansion mismatch and promote thermal transfer to the flex circuit. TAB outer lead bonds are parallel gap welded (PGW) to the flex circuit to finish the concentrator solar cell subassembly.

  9. Finite micro-tab system for load control on a wind turbine

    NASA Astrophysics Data System (ADS)

    Bach, A. B.; Lennie, M.; Pechlivanoglou, G.; Nayeri, C. N.; Paschereit, C. O.

    2014-06-01

    Finite micro-tabs have been investigated experimentally to evaluate the potential for load control on wind turbines. Two dimensional full span, as well as multiple finite tabs of various aspect ratios have been studied on an AH93W174 airfoil at different chord wise positions. A force balance was used to measure the aerodynamic loads. Furthermore, the wake vortex system consisting of the Karman vortex street as well as the tab tip vortices was analyzed with a 12-hole probe and hot wire anemometry. Finally, conventional oil paint as well as a quantitative digital flow analysis technique called SMARTviz were used to visualize the flow around the finite tab configurations. Results have shown that the devices are an effective solution to alleviate the airfoils overall load. The influence of the tab height, tab position as well as the finite tab aspect ratio on the lift and lift to drag ratio have been evaluated. It could be shown, that the lift difference can either be varied by changing the tab height as well as by altering the aspect ratio of the finite tabs. The drag of a two-dimensional flap is directly associated with the vortex street, while in the case of the finite tab, the solidity ratio of the tabs has the strongest effect on the drag. Therefore, the application of a finite tab system showed to improve the lift to drag ratio.

  10. Phylogenetic Pattern, Evolutionary Processes and Species Delimitation in the Genus Echinococcus.

    PubMed

    Lymbery, A J

    2017-01-01

    An accurate and stable alpha taxonomy requires a clear conception of what constitutes a species and agreed criteria for delimiting different species. An evolutionary or general lineage concept defines a species as a single lineage of organisms with a common evolutionary trajectory, distinguishable from other such lineages. Delimiting evolutionary species is a two-step process. In the first step, phylogenetic reconstruction identifies putative species as groups of organisms that are monophyletic (share a common ancestor) and exclusive (more closely related to each other than to organisms outside the group). The second step is to assess whether members of the group possess genetic exchangeability (where cohesion is maintained by gene flow among populations) or ecological exchangeability (where cohesion is maintained because populations occupy the same ecological niche). Recent taxonomic reviews have recognized nine species within the genus Echinococcus. Phylogenetic reconstructions of the relationships between these putative species using mtDNA and nuclear gene sequences show that for the most part these nine species are monophyletic, although there are important incongruences that need to be resolved. Applying the criteria of genetic and ecological exchangeability suggests that seven of the currently recognized species represent evolutionarily distinct lineages. The species status of Echinococcus canadensis and Echinococcus ortleppi could not be confirmed. Coalescent-based analyses represent a promising approach to species delimitation in these closely related taxa. It seems likely, from a comparison of sister species groups, that speciation in the genus has been driven by geographic isolation, but biogeographic scenarios are largely speculative and require further testing. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. Phylogenetic Reconstruction, Morphological Diversification and Generic Delimitation of Disepalum (Annonaceae)

    PubMed Central

    Li, Pui-Sze; Thomas, Daniel C.; Saunders, Richard M. K.

    2015-01-01

    Taxonomic delimitation of Disepalum (Annonaceae) is contentious, with some researchers favoring a narrow circumscription following segregation of the genus Enicosanthellum. We reconstruct the phylogeny of Disepalum and related taxa based on four chloroplast and two nuclear DNA regions as a framework for clarifying taxonomic delimitation and assessing evolutionary transitions in key morphological characters. Maximum parsimony, maximum likelihood and Bayesian methods resulted in a consistent, well-resolved and strongly supported topology. Disepalum s.l. is monophyletic and strongly supported, with Disepalum s.str. and Enicosanthellum retrieved as sister groups. Although this topology is consistent with both taxonomic delimitations, the distribution of morphological synapomorphies provides greater support for the inclusion of Enicosanthellum within Disepalum s.l. We propose a novel infrageneric classification with two subgenera. Subgen. Disepalum (= Disepalum s.str.) is supported by numerous synapomorphies, including the reduction of the calyx to two sepals and connation of petals. Subgen. Enicosanthellum lacks obvious morphological synapomorphies, but possesses several diagnostic characters (symplesiomorphies), including a trimerous calyx and free petals in two whorls. We evaluate changes in petal morphology in relation to hypotheses of the genetic control of floral development and suggest that the compression of two petal whorls into one and the associated fusion of contiguous petals may be associated with the loss of the pollination chamber, which in turn may be associated with a shift in primary pollinator. We also suggest that the formation of pollen octads may be selectively advantageous when pollinator visits are infrequent, although this would only be applicable if multiple ovules could be fertilized by each octad; since the flowers are apocarpous, this would require an extragynoecial compitum to enable intercarpellary growth of pollen tubes. We furthermore

  12. linkedISA: semantic representation of ISA-Tab experimental metadata.

    PubMed

    González-Beltrán, Alejandra; Maguire, Eamonn; Sansone, Susanna-Assunta; Rocca-Serra, Philippe

    2014-01-01

    Reporting and sharing experimental metadata- such as the experimental design, characteristics of the samples, and procedures applied, along with the analysis results, in a standardised manner ensures that datasets are comprehensible and, in principle, reproducible, comparable and reusable. Furthermore, sharing datasets in formats designed for consumption by humans and machines will also maximize their use. The Investigation/Study/Assay (ISA) open source metadata tracking framework facilitates standards-compliant collection, curation, visualization, storage and sharing of datasets, leveraging on other platforms to enable analysis and publication. The ISA software suite includes several components used in increasingly diverse set of life science and biomedical domains; it is underpinned by a general-purpose format, ISA-Tab, and conversions exist into formats required by public repositories. While ISA-Tab works well mainly as a human readable format, we have also implemented a linked data approach to semantically define the ISA-Tab syntax. We present a semantic web representation of the ISA-Tab syntax that complements ISA-Tab's syntactic interoperability with semantic interoperability. We introduce the linkedISA conversion tool from ISA-Tab to the Resource Description Framework (RDF), supporting mappings from the ISA syntax to multiple community-defined, open ontologies and capitalising on user-provided ontology annotations in the experimental metadata. We describe insights of the implementation and how annotations can be expanded driven by the metadata. We applied the conversion tool as part of Bio-GraphIIn, a web-based application supporting integration of the semantically-rich experimental descriptions. Designed in a user-friendly manner, the Bio-GraphIIn interface hides most of the complexities to the users, exposing a familiar tabular view of the experimental description to allow seamless interaction with the RDF representation, and visualising descriptors to

  13. Integrative taxonomy by molecular species delimitation: multi-locus data corroborate a new species of Balkan Drusinae micro-endemics.

    PubMed

    Vitecek, Simon; Kučinić, Mladen; Previšić, Ana; Živić, Ivana; Stojanović, Katarina; Keresztes, Lujza; Bálint, Miklós; Hoppeler, Felicitas; Waringer, Johann; Graf, Wolfram; Pauls, Steffen U

    2017-06-06

    Taxonomy offers precise species identification and delimitation and thus provides basic information for biological research, e.g. through assessment of species richness. The importance of molecular taxonomy, i.e., the identification and delimitation of taxa based on molecular markers, has increased in the past decade. Recently developed exploratory tools now allow estimating species-level diversity in multi-locus molecular datasets. Here we use molecular species delimitation tools that either quantify differences in intra- and interspecific variability of loci, or divergence times within and between species, or perform coalescent species tree inference to estimate species-level entities in molecular genetic datasets. We benchmark results from these methods against 14 morphologically readily differentiable species of a well-defined subgroup of the diverse Drusinae subfamily (Trichoptera, Limnephilidae). Using a 3798 bp (6 loci) molecular data set we aim to corroborate a geographically isolated new species by integrating comparative morphological studies and molecular taxonomy. Our results indicate that only multi-locus species delimitation provides taxonomically relevant information. The data further corroborate the new species Drusus zivici sp. nov. We provide differential diagnostic characters and describe the male, female and larva of this new species and discuss diversity patterns of Drusinae in the Balkans. We further discuss potential and significance of molecular species delimitation. Finally we argue that enhancing collaborative integrative taxonomy will accelerate assessment of global diversity and completion of reference libraries for applied fields, e.g., conservation and biomonitoring.

  14. Delimiting family in syntheses of research on childhood chronic conditions and family life.

    PubMed

    Knafl, Kathleen; Leeman, Jennifer; Havill, Nancy; Crandell, Jamie; Sandelowski, Margarete

    2015-03-01

    Synthesis of family research presents unique challenges to investigators who must delimit what will be included as a family study in the proposed review. In this paper, the authors discuss the conceptual and pragmatic challenges of conducting systematic reviews of the literature on the intersection between family life and childhood chronic conditions. A proposed framework for delimiting the family domain of interest is presented. The framework addresses both topical salience and level of relevance and provides direction to future researchers, with the goal of supporting the overall quality of family research synthesis efforts. For users of synthesis studies, knowledge of how investigators conceptualize the boundaries of family research is important contextual information for understanding the limits and applicability of the results. © 2014 Family Process Institute.

  15. The influence of locus number and information content on species delimitation: an empirical test case in an endangered Mexican salamander.

    PubMed

    Hime, Paul M; Hotaling, Scott; Grewelle, Richard E; O'Neill, Eric M; Voss, S Randal; Shaffer, H Bradley; Weisrock, David W

    2016-12-01

    Perhaps the most important recent advance in species delimitation has been the development of model-based approaches to objectively diagnose species diversity from genetic data. Additionally, the growing accessibility of next-generation sequence data sets provides powerful insights into genome-wide patterns of divergence during speciation. However, applying complex models to large data sets is time-consuming and computationally costly, requiring careful consideration of the influence of both individual and population sampling, as well as the number and informativeness of loci on species delimitation conclusions. Here, we investigated how locus number and information content affect species delimitation results for an endangered Mexican salamander species, Ambystoma ordinarium. We compared results for an eight-locus, 137-individual data set and an 89-locus, seven-individual data set. For both data sets, we used species discovery methods to define delimitation models and species validation methods to rigorously test these hypotheses. We also used integrated demographic model selection tools to choose among delimitation models, while accounting for gene flow. Our results indicate that while cryptic lineages may be delimited with relatively few loci, sampling larger numbers of loci may be required to ensure that enough informative loci are available to accurately identify and validate shallow-scale divergences. These analyses highlight the importance of striking a balance between dense sampling of loci and individuals, particularly in shallowly diverged lineages. They also suggest the presence of a currently unrecognized, endangered species in the western part of A. ordinarium's range. © 2016 John Wiley & Sons Ltd.

  16. Caryoscope: An Open Source Java application for viewing microarray data in a genomic context

    PubMed Central

    Awad, Ihab AB; Rees, Christian A; Hernandez-Boussard, Tina; Ball, Catherine A; Sherlock, Gavin

    2004-01-01

    Background Microarray-based comparative genome hybridization experiments generate data that can be mapped onto the genome. These data are interpreted more easily when represented graphically in a genomic context. Results We have developed Caryoscope, which is an open source Java application for visualizing microarray data from array comparative genome hybridization experiments in a genomic context. Caryoscope can read General Feature Format files (GFF files), as well as comma- and tab-delimited files, that define the genomic positions of the microarray reporters for which data are obtained. The microarray data can be browsed using an interactive, zoomable interface, which helps users identify regions of chromosomal deletion or amplification. The graphical representation of the data can be exported in a number of graphic formats, including publication-quality formats such as PostScript. Conclusion Caryoscope is a useful tool that can aid in the visualization, exploration and interpretation of microarray data in a genomic context. PMID:15488149

  17. TabPath: interactive tables for metabolic pathway analysis.

    PubMed

    Moraes, Lauro Ângelo Gonçalves de; Felestrino, Érica Barbosa; Assis, Renata de Almeida Barbosa; Matos, Diogo; Lima, Joubert de Castro; Lima, Leandro de Araújo; Almeida, Nalvo Franco; Setubal, João Carlos; Garcia, Camila Carrião Machado; Moreira, Leandro Marcio

    2018-03-15

    Information about metabolic pathways in a comparative context is one of the most powerful tool to help the understanding of genome-based differences in phenotypes among organisms. Although several platforms exist that provide a wealth of information on metabolic pathways of diverse organisms, the comparison among organisms using metabolic pathways is still a difficult task. We present TabPath (Tables for Metabolic Pathway), a web-based tool to facilitate comparison of metabolic pathways in genomes based on KEGG. From a selection of pathways and genomes of interest on the menu, TabPath generates user-friendly tables that facilitate analysis of variations in metabolism among the selected organisms. TabPath is available at http://200.239.132.160:8686. lmmorei@gmail.com.

  18. 5 CFR 1201.137 - Covered actions; filing complaint; serving documents on parties.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) Reduction in grade; (4) Reduction in pay; and (5) Furlough of 30 days or less. (b) Place of filing. To... complaint, together with numbered and tabbed exhibits or attachments, if any, and a certificate of service...

  19. 5 CFR 1201.137 - Covered actions; filing complaint; serving documents on parties.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) Reduction in grade; (4) Reduction in pay; and (5) Furlough of 30 days or less. (b) Place of filing. To... complaint, together with numbered and tabbed exhibits or attachments, if any, and a certificate of service...

  20. Issues and Perspectives in Species Delimitation using Phenotypic Data: Atlantean Evolution in Darwin's Finches.

    PubMed

    Cadena, Carlos Daniel; Zapata, Felipe; Jiménez, Iván

    2018-03-01

    Progress in the development and use of methods for species delimitation employing phenotypic data lags behind conceptual and practical advances in molecular genetic approaches. The basic evolutionary model underlying the use of phenotypic data to delimit species assumes random mating and quantitative polygenic traits, so that phenotypic distributions within a species should be approximately normal for individuals of the same sex and age. Accordingly, two or more distinct normal distributions of phenotypic traits suggest the existence of multiple species. In light of this model, we show that analytical approaches employed in taxonomic studies using phenotypic data are often compromised by three issues: 1) reliance on graphical analyses that convey little information on phenotype frequencies; 2) exclusion of characters potentially important for species delimitation following reduction of data dimensionality; and 3) use of measures of central tendency to evaluate phenotypic distinctiveness. We outline approaches to overcome these issues based on statistical developments related to normal mixture models (NMMs) and illustrate them empirically with a reanalysis of morphological data recently used to claim that there are no morphologically distinct species of Darwin's ground-finches (Geospiza). We found negligible support for this claim relative to taxonomic hypotheses recognizing multiple species. Although species limits among ground-finches merit further assessments using additional sources of information, our results bear implications for other areas of inquiry including speciation research: because ground-finches have likely speciated and are not trapped in a process of "Sisyphean" evolution as recently argued, they remain useful models to understand the evolutionary forces involved in speciation. Our work underscores the importance of statistical approaches grounded on appropriate evolutionary models for species delimitation. We discuss how NMMs offer new

  1. Skeletal muscle proteins: a new approach to delimitate the time since death.

    PubMed

    Foditsch, Elena Esra; Saenger, Alexandra Maria; Monticelli, Fabio Carlo

    2016-03-01

    Skeletal muscle tissue is proposed as a forensic model tissue with strong potential, as it is easily accessible and its true-to-life state structure and function is well known. Despite this strong potential, skeletal muscle degradation studies are rare. The aim of this study was to test if a skeletal muscle-based protein analysis is applicable to delimitate the time since death. Under standard conditions, two pigs were stored either at 22 °C for 5 days or 4 °C for 21 days. Their Mm. biceps femori were sampled periodically for analyses of ten skeletal muscle proteins postmortem. All analyzed proteins can serve as markers for a delimitation of the time since death. Desmin, nebulin, titin, and SERCA 1 displayed distinct protein patterns at certain points of time. The other five proteins, α-actinin, calsequestrin-1, laminin, troponin T-C, and SERCA 2, showed no degradation patterns within the analyzed postmortem time frame. Referring to specific skeletal muscle proteins, results showed short-term stabilities for just a minority of analyzed proteins, while the majority of investigated proteins displayed characteristics as long-term markers. Due to specific patterns and the possibility to determine definite constraints of the presence, absence, or pattern alterations of single proteins, the feasibility of porcine skeletal muscle as forensic model tissue is outlined and the potential of skeletal muscle as forensic model tissue is underlined, especially with respect to later postmortem phases, which so far lack feasible methods to delimitate the time since death.

  2. Comparative molecular species delimitation in the charismatic Nawab butterflies (Nymphalidae, Charaxinae, Polyura).

    PubMed

    Toussaint, Emmanuel F A; Morinière, Jérôme; Müller, Chris J; Kunte, Krushnamegh; Turlin, Bernard; Hausmann, Axel; Balke, Michael

    2015-10-01

    The charismatic tropical Polyura Nawab butterflies are distributed across twelve biodiversity hotspots in the Indomalayan/Australasian archipelago. In this study, we tested an array of species delimitation methods and compared the results to existing morphology-based taxonomy. We sequenced two mitochondrial and two nuclear gene fragments to reconstruct phylogenetic relationships within Polyura using both Bayesian inference and maximum likelihood. Based on this phylogenetic framework, we used the recently introduced bGMYC, BPP and PTP methods to investigate species boundaries. Based on our results, we describe two new species Polyura paulettae Toussaint sp. n. and Polyura smilesi Toussaint sp. n., propose one synonym, and five populations are raised to species status. Most of the newly recognized species are single-island endemics likely resulting from the recent highly complex geological history of the Indomalayan-Australasian archipelago. Surprisingly, we also find two newly recognized species in the Indomalayan region where additional biotic or abiotic factors have fostered speciation. Species delimitation methods were largely congruent and succeeded to cross-validate most extant morphological species. PTP and BPP seem to yield more consistent and robust estimations of species boundaries with respect to morphological characters while bGMYC delivered contrasting results depending on the different gene trees considered. Our findings demonstrate the efficiency of comparative approaches using molecular species delimitation methods on empirical data. They also pave the way for the investigation of less well-known groups to unveil patterns of species richness and catalogue Earth's concealed, therefore unappreciated diversity. Published by Elsevier Inc.

  3. Reversal in Spreading of a Tabbed Circular Jet Under Controlled Excitation

    NASA Technical Reports Server (NTRS)

    Zaman, K. B. M. Q.; Raman, G.

    1997-01-01

    Detailed flow field measurements have been carried out for a turbulent circular jet perturbed by tabs and artificial excitation. Two "delta tabs" were placed at the nozzle exit at diametricall opposite y locations. The excitation condition involved subharmonic resonance that manifested in a periodic vortex pairing in the near flow field. While the excitation and the tabs independently increased jet spreading, a combination of the two diminished the effect. The jet spreading was most pronounced with the tabs but was reduced when excitation was applied to the tabbed jet. The tabs generated streamwise vortex pairs that caused a lateral spreading of the jet in a direction perpendicular to the plane containing the tabs. ne excitation, on the other hand, organized the azimuthal vorticity into coherent ring structures whose evolution and pairing also increased entrainment by the jet. In the tabbed case, the excitation produced coherent azimuthal structures that were distorted and asymmetric in shape. The self-induction of these structures produced an effect that opposed the tendency for the lateral spreading of the streamwise vortex pairs. The passage of the distorted vortices, and their pairing, also had a cancellation effect on the time-averaged streamwise vorticity field. These led to the reduction in jet spreading.

  4. Assessment of multiresolution segmentation for delimiting drumlins in digital elevation models.

    PubMed

    Eisank, Clemens; Smith, Mike; Hillier, John

    2014-06-01

    Mapping or "delimiting" landforms is one of geomorphology's primary tools. Computer-based techniques such as land-surface segmentation allow the emulation of the process of manual landform delineation. Land-surface segmentation exhaustively subdivides a digital elevation model (DEM) into morphometrically-homogeneous irregularly-shaped regions, called terrain segments. Terrain segments can be created from various land-surface parameters (LSP) at multiple scales, and may therefore potentially correspond to the spatial extents of landforms such as drumlins. However, this depends on the segmentation algorithm, the parameterization, and the LSPs. In the present study we assess the widely used multiresolution segmentation (MRS) algorithm for its potential in providing terrain segments which delimit drumlins. Supervised testing was based on five 5-m DEMs that represented a set of 173 synthetic drumlins at random but representative positions in the same landscape. Five LSPs were tested, and four variants were computed for each LSP to assess the impact of median filtering of DEMs, and logarithmic transformation of LSPs. The testing scheme (1) employs MRS to partition each LSP exhaustively into 200 coarser scales of terrain segments by increasing the scale parameter ( SP ), (2) identifies the spatially best matching terrain segment for each reference drumlin, and (3) computes four segmentation accuracy metrics for quantifying the overall spatial match between drumlin segments and reference drumlins. Results of 100 tests showed that MRS tends to perform best on LSPs that are regionally derived from filtered DEMs, and then log-transformed. MRS delineated 97% of the detected drumlins at SP values between 1 and 50. Drumlin delimitation rates with values up to 50% are in line with the success of manual interpretations. Synthetic DEMs are well-suited for assessing landform quantification methods such as MRS, since subjectivity in the reference data is avoided which increases the

  5. Cryptic diversity and discordance in single-locus species delimitation methods within horned lizards (Phrynosomatidae: Phrynosoma).

    PubMed

    Blair, Christopher; Bryson, Robert W

    2017-11-01

    Biodiversity reduction and loss continues to progress at an alarming rate, and thus, there is widespread interest in utilizing rapid and efficient methods for quantifying and delimiting taxonomic diversity. Single-locus species delimitation methods have become popular, in part due to the adoption of the DNA barcoding paradigm. These techniques can be broadly classified into tree-based and distance-based methods depending on whether species are delimited based on a constructed genealogy. Although the relative performance of these methods has been tested repeatedly with simulations, additional studies are needed to assess congruence with empirical data. We compiled a large data set of mitochondrial ND4 sequences from horned lizards (Phrynosoma) to elucidate congruence using four tree-based (single-threshold GMYC, multiple-threshold GMYC, bPTP, mPTP) and one distance-based (ABGD) species delimitation models. We were particularly interested in cases with highly uneven sampling and/or large differences in intraspecific diversity. Results showed a high degree of discordance among methods, with multiple-threshold GMYC and bPTP suggesting an unrealistically high number of species (29 and 26 species within the P. douglasii complex alone). The single-threshold GMYC model was the most conservative, likely a result of difficulty in locating the inflection point in the genealogies. mPTP and ABGD appeared to be the most stable across sampling regimes and suggested the presence of additional cryptic species that warrant further investigation. These results suggest that the mPTP model may be preferable in empirical data sets with highly uneven sampling or large differences in effective population sizes of species. © 2017 John Wiley & Sons Ltd.

  6. Delimiting species of Protaphorura (Collembola: Onychiuridae): integrative evidence based on morphology, DNA sequences and geography.

    PubMed

    Sun, Xin; Zhang, Feng; Ding, Yinhuan; Davies, Thomas W; Li, Yu; Wu, Donghui

    2017-08-15

    Species delimitation remains a significant challenge when the diagnostic morphological characters are limited. Integrative taxonomy was applied to the genus Protaphorura (Collembola: Onychiuridae), which is one of most difficult soil animals to distinguish taxonomically. Three delimitation approaches (morphology, molecular markers and geography) were applied providing rigorous species validation criteria with an acceptably low error rate. Multiple molecular approaches, including distance- and evolutionary model-based methods, were used to determine species boundaries based on 144 standard barcode sequences. Twenty-two molecular putative species were consistently recovered across molecular and geographical analyses. Geographic criteria were was proved to be an efficient delimitation method for onychiurids. Further morphological examination, based on the combination of the number of pseudocelli, parapseudocelli and ventral mesothoracic chaetae, confirmed 18 taxa of 22 molecular units, with six of them described as new species. These characters were found to be of high taxonomical value. This study highlights the potential benefits of integrative taxonomy, particularly simultaneous use of molecular/geographical tools, as a powerful way of ascertaining the true diversity of the Onychiuridae. Our study also highlights that discovering new morphological characters remains central to achieving a full understanding of collembolan taxonomy.

  7. 5 CFR 1201.134 - Deciding official; filing stay request; serving documents on parties.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... motion for extension or termination of the stay. (c) Place of filing. A Special Counsel stay request must... two copies of the request, together with numbered and tabbed exhibits or attachments, if any, and a...

  8. NCEP BUFR File Structure

    Science.gov Websites

    . These tables may be defined within a separate ASCII text file (see Description and Format of BUFR Tables time, the BUFR tables are usually read from an external ASCII text file (although it is also possible reports. Click here to view the ASCII text file (called /nwprod/fix/bufrtab.002 on the NCEP CCS machines

  9. Apparatus for preparing cornea material for tabbed (sutureless) transplantation

    DOEpatents

    Collins, Joseph Patrick

    1997-01-01

    A tool and a method for preparing a donor material used in sutureless corneal transplants uses a first cutting portion to prepare a donor blank having tabbed portions extending outwardly radially. A second cutting portion is used to cut the central portion of the blank. The tool is used as a guide member for the second cutting portion. In one embodiment the tool has slits laterally defined therethrough which allow the tabbed portions of the donor material to be thinned to a desired thickness using a scalpel. In an another embodiment the second cutting portion is a round trephine which is used to simultaneously trim each of the tabbed portions.

  10. Identification and functional characterization of the TAB2 gene from Litopenaeus vannamei.

    PubMed

    Wang, Sheng; Li, Haoyang; Qian, Zhe; Song, Xuan; Zhang, Zijian; Zuo, Hongliang; Xu, Xiaopeng; Weng, Shaoping; He, Jianguo; Li, Chaozheng

    2015-10-01

    In Drosophila, TAB2, an important intermediate in the IMD signaling pathway, plays critical roles in the innate immune response in response to bacterial and viral infection. However, the role of TAB-related proteins in the immune response of shrimp has not yet been established. Here, we reported the identification of a TAB2-like gene in Litopenaeus vannamei designated as LvTAB2. The full-length cDNA of LvTAB2 was 2160 bp with an open reading frame of 1827 bp, which encoded a putative protein of 608 amino acids including a ubiquitin binding domain (CUE) at the N-terminal and a Zinc Finger domain (ZnF) at the C-terminus. Real-time RT-PCR analysis showed that LvTAB2 was expressed in all tested tissues and the expression levels of LvTAB2 in gills and hemocytes were positively induced in response to LPS, Vibrio parahemolyticus and White Spot Syndrome Virus (WSSV) challenges. Dual luciferase reporter assays demonstrated that LvTAB2 was able to induce the expression of antimicrobial peptide (AMP) genes, including Drosophila Attacin A and shrimp Penaeidins. Interestingly, over-expression of LvTAB2 could up-regulate the promoter activities of L. vannamei Vago1, Vago3 and Vago4 genes in S2 cells. To our knowledge, it was the first report that TAB2 participated in innate immune signaling to regulate the expression of Vago genes in invertebrates. Moreover, RNAi-mediated knockdown of LvTAB2 enhanced sensitivity of L. vannamei to Vibrio parahaemolyticus infection and caused elevated virus loads after WSSV infection. We suggested that the LvTAB2 may play important roles in the shrimp innate immunity. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. Subsonic Jet Noise from Non-Axisymmetric and Tabbed Nozzles

    NASA Technical Reports Server (NTRS)

    Zaman, K. B. M. Q.; Tam, Christopher K. W.

    1999-01-01

    Subsonic jet noise from non-axisymmetric and tabbed nozzles are investigated experimentally and theoretically. It is shown that the noise spectra of these jets are in good agreement with the similarity spectra found empirically earlier by Tam, Golebiowski and Seiner through a detailed analysis of supersonic jet noise data. Further, the radiated noise fields of the jets under study, including elliptic and large aspect ratio rectangular jets, are found to be quite axisymmetric and are practically the same as that of a circular jet with the same exit area. These experimental results strongly suggest that nozzle geometry modification into elliptic or rectangular shapes is not an effective method for jet noise suppression. A lobed nozzle, on the other hand, is found to significantly impact the noise field. Noise from large scale turbulent structures, radiating principally in the downstream direction, is effectively suppressed. Tabs also impact the noise field, primarily by shifting the spectral peak to a higher frequency. A jetlets model is developed to provide a basic understanding of the noise from tabbed jets. The model predicts that the noise spectrum from a jet with N tabs (N > 2) can be obtained from that of the original jet (no tab) by a simple frequency shift. The shifted frequency is obtained by multiplying the original frequency by N(sup 1/2). This result is in fairly good agreement with experimental data.

  12. Rigorous approaches to species delimitation have significant implications for African crocodilian systematics and conservation

    PubMed Central

    Shirley, Matthew H.; Vliet, Kent A.; Carr, Amanda N.; Austin, James D.

    2014-01-01

    Accurate species delimitation is a central assumption of biology that, in groups such as the Crocodylia, is often hindered by highly conserved morphology and frequent introgression. In Africa, crocodilian systematics has been hampered by complex regional biogeography and confounded taxonomic history. We used rigorous molecular and morphological species delimitation methods to test the hypothesis that the slender-snouted crocodile (Mecistops cataphractus) is composed of multiple species corresponding to the Congolian and Guinean biogeographic zones. Speciation probability was assessed by using 11 mitochondrial and nuclear genes, and cranial morphology for over 100 specimens, representing the full geographical extent of the species distribution. Molecular Bayesian and phylogenetic species delimitation showed unanimous support for two Mecistops species isolated to the Upper Guinean and Congo (including Lower Guinean) biomes that were supported by 13 cranial characters capable of unambiguously diagnosing each species. Fossil-calibrated phylogenetic reconstruction estimated that the species split ± 6.5–7.5 Ma, which is congruent with intraspecies divergence within the sympatric crocodile genus Osteolaemus and the formation of the Cameroon Volcanic Line. Our results underscore the necessity of comprehensive phylogeographic analyses within currently recognized taxa to detect cryptic species within the Crocodylia. We recommend that the community of crocodilian researchers reconsider the conceptualization of crocodilian species especially in the light of the conservation ramifications for this economically and ecologically important group. PMID:24335982

  13. FTP: Full-Text Publishing?

    ERIC Educational Resources Information Center

    Jul, Erik

    1992-01-01

    Describes the use of file transfer protocol (FTP) on the INTERNET computer network and considers its use as an electronic publishing system. The differing electronic formats of text files are discussed; the preparation and access of documents are described; and problems are addressed, including a lack of consistency. (LRW)

  14. Apparatus for preparing cornea material for tabbed (sutureless) transplantation

    DOEpatents

    Collins, J.P.

    1997-07-22

    A tool and a method for preparing a donor material used in sutureless corneal transplants uses a first cutting portion to prepare a donor blank having tabbed portions extending outwardly radially. A second cutting portion is used to cut the central portion of the blank. The tool is used as a guide member for the second cutting portion. In one embodiment the tool has slits laterally defined therethrough which allow the tabbed portions of the donor material to be thinned to a desired thickness using a scalpel. In an another embodiment the second cutting portion is a round trephine which is used to simultaneously trim each of the tabbed portions. 26 figs.

  15. Species delimitation in northern European water scavenger beetles of the genus Hydrobius (Coleoptera, Hydrophilidae)

    PubMed Central

    Fossen, Erlend I.; Ekrem, Torbjørn; Nilsson, Anders N.; Bergsten, Johannes

    2016-01-01

    Abstract The chiefly Holarctic Hydrobius species complex (Coleoptera, Hydrophilidae) currently consists of Hydrobius arcticus Kuwert, 1890, and three morphological variants of Hydrobius fuscipes (Linnaeus, 1758): var. fuscipes, var. rottenbergii and var. subrotundus in northern Europe. Here molecular and morphological data are used to test the species boundaries in this species complex. Three gene segments (COI, H3 and ITS2) were sequenced and analyzed with Bayesian methods to infer phylogenetic relationships. The Generalized Mixed Yule Coalescent (GMYC) model and two versions of the Bayesian species delimitation method BPP, with or without an a priori defined guide tree (v2.2 & v3.0), were used to evaluate species limits. External and male genital characters of primarily Fennoscandian specimens were measured and statistically analyzed to test for significant differences in quantitative morphological characters. The four morphotypes formed separate genetic clusters on gene trees and were delimited as separate species by GMYC and by both versions of BPP, despite specimens of Hydrobius fuscipes var. fuscipes and Hydrobius fuscipes var. subrotundus being sympatric. Hydrobius arcticus and Hydrobius fuscipes var. rottenbergii could only be separated genetically with ITS2, and were delimited statistically with GMYC on ITS2 and with BPP on the combined data. In addition, six or seven potentially cryptic species of the Hydrobius fuscipes complex from regions outside northern Europe were delimited genetically. Although some overlap was found, the mean values of six male genital characters were significantly different between the morphotypes (p < 0.001). Morphological characters previously presumed to be diagnostic were less reliable to separate Hydrobius fuscipes var. fuscipes from Hydrobius fuscipes var. subrotundus, but characters in the literature for Hydrobius arcticus and Hydrobius fuscipes var. rottenbergii were diagnostic. Overall, morphological and molecular

  16. Subsonic Jet Noise from Non-Axisymmetric and Tabbed Nozzles

    NASA Technical Reports Server (NTRS)

    Tam, Christopher K. W.; Zaman, K. B. M. Q.

    1999-01-01

    Subsonic jet noise from non-axisymmetric and tabbed nozzles are investigated experimentally and theoretically. It is shown that the noise spectra of these jets are in good agreement with the similarity spectra found empirically earlier by Tam, Golebiowski and Seiner through a detailed analysis of supersonic jet noise data. Further, the radiated noise fields of the jets under study, including elliptic and large aspect ratio rectangular jets, are found to be quite axisymmetric and are practically the same as that of a circular jet with the same exit area. These experimental results strongly suggest that nozzle geometry modification into elliptic or rectangular shapes is not an effective method for jet noise suppression. A lobed nozzle, on the other hand, is found to significantly impact the noise field. Noise from large scale turbulent structures, radiating principally in the downstream direction, is effectively suppressed. Tabs also impact the noise field, primarily by shifting the spectral peak to a higher frequency. A jetlets model is developed to provide a basic understanding of the noise from tabbed jets. The model predicts that the noise spectrum from a jet with N tabs (N greater than or equal to 2) can be obtained from that of the original jet (no tab) by a simple frequency shift. The shifted frequency is obtained by multiplying the original frequency by N(exp 1/2). This result is in fairly good agreement with experimental data.

  17. On the difficulty to delimit disease risk hot spots

    NASA Astrophysics Data System (ADS)

    Charras-Garrido, M.; Azizi, L.; Forbes, F.; Doyle, S.; Peyrard, N.; Abrial, D.

    2013-06-01

    Representing the health state of a region is a helpful tool to highlight spatial heterogeneity and localize high risk areas. For ease of interpretation and to determine where to apply control procedures, we need to clearly identify and delineate homogeneous regions in terms of disease risk, and in particular disease risk hot spots. However, even if practical purposes require the delineation of different risk classes, such a classification does not correspond to a reality and is thus difficult to estimate. Working with grouped data, a first natural choice is to apply disease mapping models. We apply a usual disease mapping model, producing continuous estimations of the risks that requires a post-processing classification step to obtain clearly delimited risk zones. We also apply a risk partition model that build a classification of the risk levels in a one step procedure. Working with point data, we will focus on the scan statistic clustering method. We illustrate our article with a real example concerning the bovin spongiform encephalopathy (BSE) an animal disease whose zones at risk are well known by the epidemiologists. We show that in this difficult case of a rare disease and a very heterogeneous population, the different methods provide risk zones that are globally coherent. But, related to the dichotomy between the need and the reality, the exact delimitation of the risk zones, as well as the corresponding estimated risks are quite different.

  18. Experimental and computational investigation of lift-enhancing tabs on a multi-element airfoil

    NASA Technical Reports Server (NTRS)

    Ashby, Dale

    1996-01-01

    An experimental and computational investigation of the effect of lift enhancing tabs on a two-element airfoil was conducted. The objective of the study was to develop an understanding of the flow physics associated with lift enhancing tabs on a multi-element airfoil. A NACA 63(sub 2)-215 ModB airfoil with a 30 percent chord Fowler flap was tested in the NASA Ames 7 by 10 foot wind tunnel. Lift enhancing tabs of various heights were tested on both the main element and the flap for a variety of flap riggings. Computations of the flow over the two-element airfoil were performed using the two-dimensional incompressible Navier-Stokes code INS2D-UP. The computer results predict all of the trends in the experimental data quite well. When the flow over the flap upper surface is attached, tabs mounted at the main element trailing edge (cove tabs) produce very little change in lift. At high flap deflections. however, the flow over the flap is separated and cove tabs produce large increases in lift and corresponding reductions in drag by eliminating the separated flow. Cove tabs permit high flap deflection angles to be achieved and reduce the sensitivity of the airfoil lift to the size of the flap gap. Tabs attached to the flap training edge (flap tabs) are effective at increasing lift without significantly increasing drag. A combination of a cove tab and a flap tab increased the airfoil lift coefficient by 11 percent relative to the highest lift tab coefficient achieved by any baseline configuration at an angle of attack of zero percent and the maximum lift coefficient was increased by more than 3 percent. A simple analytic model based on potential flow was developed to provide a more detailed understanding of how lift enhancing tabs work. The tabs were modeled by a point vortex at the training edge. Sensitivity relationships were derived which provide a mathematical basis for explaining the effects of lift enhancing tabs on a multi-element airfoil. Results of the modeling

  19. A New Interface for the Magnetics Information Consortium (MagIC) Paleo and Rock Magnetic Database

    NASA Astrophysics Data System (ADS)

    Jarboe, N.; Minnett, R.; Koppers, A. A. P.; Tauxe, L.; Constable, C.; Shaar, R.; Jonestrask, L.

    2014-12-01

    The Magnetic Information Consortium (MagIC) database (http://earthref.org/MagIC/) continues to improve the ease of uploading data, the creation of complex searches, data visualization, and data downloads for the paleomagnetic, geomagnetic, and rock magnetic communities. Data uploading has been simplified and no longer requires the use of the Excel SmartBook interface. Instead, properly formatted MagIC text files can be dragged-and-dropped onto an HTML 5 web interface. Data can be uploaded one table at a time to facilitate ease of uploading and data error checking is done online on the whole dataset at once instead of incrementally in an Excel Console. Searching the database has improved with the addition of more sophisticated search parameters and with the ability to use them in complex combinations. Searches may also be saved as permanent URLs for easy reference or for use as a citation in a publication. Data visualization plots (ARAI, equal area, demagnetization, Zijderveld, etc.) are presented with the data when appropriate to aid the user in understanding the dataset. Data from the MagIC database may be downloaded from individual contributions or from online searches for offline use and analysis in the tab delimited MagIC text file format. With input from the paleomagnetic, geomagnetic, and rock magnetic communities, the MagIC database will continue to improve as a data warehouse and resource.

  20. The Species versus Subspecies Conundrum: Quantitative Delimitation from Integrating Multiple Data Types within a Single Bayesian Approach in Hercules Beetles.

    PubMed

    Huang, Jen-Pan; Knowles, L Lacey

    2016-07-01

    With the recent attention and focus on quantitative methods for species delimitation, an overlooked but equally important issue regards what has actually been delimited. This study investigates the apparent arbitrariness of some taxonomic distinctions, and in particular how species and subspecies are assigned. Specifically, we use a recently developed Bayesian model-based approach to show that in the Hercules beetles (genus Dynastes) there is no statistical difference in the probability that putative taxa represent different species, irrespective of whether they were given species or subspecies designations. By considering multiple data types, as opposed to relying exclusively on genetic data alone, we also show that both previously recognized species and subspecies represent a variety of points along the speciation spectrum (i.e., previously recognized species are not systematically further along the continuum than subspecies). For example, based on evolutionary models of divergence, some taxa are statistically distinguishable on more than one axis of differentiation (e.g., along both phenotypic and genetic dimensions), whereas other taxa can only be delimited statistically from a single data type. Because both phenotypic and genetic data are analyzed in a common Bayesian framework, our study provides a framework for investigating whether disagreements in species boundaries among data types reflect (i) actual discordance with the actual history of lineage splitting, or instead (ii) differences among data types in the amount of time required for differentiation to become apparent among the delimited taxa. We discuss what the answers to these questions imply about what characters are used to delimit species, as well as the diverse processes involved in the origin and maintenance of species boundaries. With this in mind, we then reflect more generally on how quantitative methods for species delimitation are used to assign taxonomic status. © The Author(s) 2015

  1. Insights into the genus Diaporthe: phylogenetic species delimitation in the D. eres species complex

    USDA-ARS?s Scientific Manuscript database

    The genus Diaporthe comprises pathogenic, endophytic and saprobic species with both temperate and tropical distributions. Cryptic diversification, phenotypic plasticity and extensive host associations have long complicated accurate identifications of species in this genus. The delimitation of the ge...

  2. SPOCS: software for predicting and visualizing orthology/paralogy relationships among genomes.

    PubMed

    Curtis, Darren S; Phillips, Aaron R; Callister, Stephen J; Conlan, Sean; McCue, Lee Ann

    2013-10-15

    At the rate that prokaryotic genomes can now be generated, comparative genomics studies require a flexible method for quickly and accurately predicting orthologs among the rapidly changing set of genomes available. SPOCS implements a graph-based ortholog prediction method to generate a simple tab-delimited table of orthologs and in addition, html files that provide a visualization of the predicted ortholog/paralog relationships to which gene/protein expression metadata may be overlaid. A SPOCS web application is freely available at http://cbb.pnnl.gov/portal/tools/spocs.html. Source code for Linux systems is also freely available under an open source license at http://cbb.pnnl.gov/portal/software/spocs.html; the Boost C++ libraries and BLAST are required.

  3. Assessing Species Boundaries Using Multilocus Species Delimitation in a Morphologically Conserved Group of Neotropical Freshwater Fishes, the Poecilia sphenops Species Complex (Poeciliidae)

    PubMed Central

    Bagley, Justin C.; Alda, Fernando; Breitman, M. Florencia; Bermingham, Eldredge; van den Berghe, Eric P.; Johnson, Jerald B.

    2015-01-01

    Accurately delimiting species is fundamentally important for understanding species diversity and distributions and devising effective strategies to conserve biodiversity. However, species delimitation is problematic in many taxa, including ‘non-adaptive radiations’ containing morphologically cryptic lineages. Fortunately, coalescent-based species delimitation methods hold promise for objectively estimating species limits in such radiations, using multilocus genetic data. Using coalescent-based approaches, we delimit species and infer evolutionary relationships in a morphologically conserved group of Central American freshwater fishes, the Poecilia sphenops species complex. Phylogenetic analyses of multiple genetic markers (sequences of two mitochondrial DNA genes and five nuclear loci) from 10/15 species and genetic lineages recognized in the group support the P. sphenops species complex as monophyletic with respect to outgroups, with eight mitochondrial ‘major-lineages’ diverged by ≥2% pairwise genetic distances. From general mixed Yule-coalescent models, we discovered (conservatively) 10 species within our concatenated mitochondrial DNA dataset, 9 of which were strongly supported by subsequent multilocus Bayesian species delimitation and species tree analyses. Results suggested species-level diversity is underestimated or overestimated by at least ~15% in different lineages in the complex. Nonparametric statistics and coalescent simulations indicate genealogical discordance among our gene tree results has mainly derived from interspecific hybridization in the nuclear genome. However, mitochondrial DNA show little evidence for introgression, and our species delimitation results appear robust to effects of this process. Overall, our findings support the utility of combining multiple lines of genetic evidence and broad phylogeographical sampling to discover and validate species using coalescent-based methods. Our study also highlights the importance of

  4. Assessing species boundaries using multilocus species delimitation in a morphologically conserved group of neotropical freshwater fishes, the Poecilia sphenops species complex (Poeciliidae).

    PubMed

    Bagley, Justin C; Alda, Fernando; Breitman, M Florencia; Bermingham, Eldredge; van den Berghe, Eric P; Johnson, Jerald B

    2015-01-01

    Accurately delimiting species is fundamentally important for understanding species diversity and distributions and devising effective strategies to conserve biodiversity. However, species delimitation is problematic in many taxa, including 'non-adaptive radiations' containing morphologically cryptic lineages. Fortunately, coalescent-based species delimitation methods hold promise for objectively estimating species limits in such radiations, using multilocus genetic data. Using coalescent-based approaches, we delimit species and infer evolutionary relationships in a morphologically conserved group of Central American freshwater fishes, the Poecilia sphenops species complex. Phylogenetic analyses of multiple genetic markers (sequences of two mitochondrial DNA genes and five nuclear loci) from 10/15 species and genetic lineages recognized in the group support the P. sphenops species complex as monophyletic with respect to outgroups, with eight mitochondrial 'major-lineages' diverged by ≥2% pairwise genetic distances. From general mixed Yule-coalescent models, we discovered (conservatively) 10 species within our concatenated mitochondrial DNA dataset, 9 of which were strongly supported by subsequent multilocus Bayesian species delimitation and species tree analyses. Results suggested species-level diversity is underestimated or overestimated by at least ~15% in different lineages in the complex. Nonparametric statistics and coalescent simulations indicate genealogical discordance among our gene tree results has mainly derived from interspecific hybridization in the nuclear genome. However, mitochondrial DNA show little evidence for introgression, and our species delimitation results appear robust to effects of this process. Overall, our findings support the utility of combining multiple lines of genetic evidence and broad phylogeographical sampling to discover and validate species using coalescent-based methods. Our study also highlights the importance of testing for

  5. Bayesian species delimitation in Pleophylla chafers (Coleoptera) - the importance of prior choice and morphology.

    PubMed

    Eberle, Jonas; Warnock, Rachel C M; Ahrens, Dirk

    2016-05-05

    Defining species units can be challenging, especially during the earliest stages of speciation, when phylogenetic inference and delimitation methods may be compromised by incomplete lineage sorting (ILS) or secondary gene flow. Integrative approaches to taxonomy, which combine molecular and morphological evidence, have the potential to be valuable in such cases. In this study we investigated the South African scarab beetle genus Pleophylla using data collected from 110 individuals of eight putative morphospecies. The dataset included four molecular markers (cox1, 16S, rrnL, ITS1) and morphometric data based on male genital morphology. We applied a suite of molecular and morphological approaches to species delimitation, and implemented a novel Bayesian approach in the software iBPP, which enables continuous morphological trait and molecular data to be combined. Traditional morphology-based species assignments were supported quantitatively by morphometric analyses of the male genitalia (eigenshape analysis, CVA, LDA). While the ITS1-based delineation was also broadly congruent with the morphospecies, the cox1 data resulted in over-splitting (GMYC modelling, haplotype networks, PTP, ABGD). In the most extreme case morphospecies shared identical haplotypes, which may be attributable to ILS based on statistical tests performed using the software JML. We found the strongest support for putative morphospecies based on phylogenetic evidence using the combined approach implemented in iBPP. However, support for putative species was sensitive to the use of alternative guide trees and alternative combinations of priors on the population size (θ) and rootage (τ 0 ) parameters, especially when the analysis was based on molecular or morphological data alone. We demonstrate that continuous morphological trait data can be extremely valuable in assessing competing hypotheses to species delimitation. In particular, we show that the inclusion of morphological data in an integrative

  6. Haploinsufficiency of TAB2 Causes Congenital Heart Defects in Humans

    PubMed Central

    Thienpont, Bernard; Zhang, Litu; Postma, Alex V.; Breckpot, Jeroen; Tranchevent, Léon-Charles; Van Loo, Peter; Møllgård, Kjeld; Tommerup, Niels; Bache, Iben; Tümer, Zeynep; van Engelen, Klaartje; Menten, Björn; Mortier, Geert; Waggoner, Darrel; Gewillig, Marc; Moreau, Yves; Devriendt, Koen; Larsen, Lars Allan

    2010-01-01

    Congenital heart defects (CHDs) are the most common major developmental anomalies and the most frequent cause for perinatal mortality, but their etiology remains often obscure. We identified a locus for CHDs on 6q24-q25. Genotype-phenotype correlations in 12 patients carrying a chromosomal deletion on 6q delineated a critical 850 kb region on 6q25.1 harboring five genes. Bioinformatics prioritization of candidate genes in this locus for a role in CHDs identified the TGF-β-activated kinase 1/MAP3K7 binding protein 2 gene (TAB2) as the top-ranking candidate gene. A role for this candidate gene in cardiac development was further supported by its conserved expression in the developing human and zebrafish heart. Moreover, a critical, dosage-sensitive role during development was demonstrated by the cardiac defects observed upon titrated knockdown of tab2 expression in zebrafish embryos. To definitively confirm the role of this candidate gene in CHDs, we performed mutation analysis of TAB2 in 402 patients with a CHD, which revealed two evolutionarily conserved missense mutations. Finally, a balanced translocation was identified, cosegregating with familial CHD. Mapping of the breakpoints demonstrated that this translocation disrupts TAB2. Taken together, these data clearly demonstrate a role for TAB2 in human cardiac development. PMID:20493459

  7. Integrating DNA barcodes and morphology for species delimitation in the Corynoneura group (Diptera: Chironomidae: Orthocladiinae).

    PubMed

    Silva, F L; Wiedenbrug, S

    2014-02-01

    In this study, we use DNA barcodes for species delimitation to solve taxonomic conflicts in 86 specimens of 14 species belonging to the Corynoneura group (Diptera: Chironomidae: Orthocladiinae), from the Atlantic Forest, Brazil. Molecular analysis of cytochrome c-oxidase subunit I (COI) gene sequences supported 14 cohesive species groups, of which two similar groups were subsequently associated with morphological variation at the pupal stage. Eleven species previously described based on morphological criteria were linked to DNA markers. Furthermore, there is the possibility that there may be cryptic species within the Corynoneura group, since one group of species presented internal grouping, although no morphological divergence was observed. Our results support DNA-barcoding as an excellent tool for species delimitation in groups where taxonomy by means of morphology is difficult or even impossible.

  8. Layout-aware text extraction from full-text PDF of scientific articles.

    PubMed

    Ramakrishnan, Cartic; Patnia, Abhishek; Hovy, Eduard; Burns, Gully Apc

    2012-05-28

    The Portable Document Format (PDF) is the most commonly used file format for online scientific publications. The absence of effective means to extract text from these PDF files in a layout-aware manner presents a significant challenge for developers of biomedical text mining or biocuration informatics systems that use published literature as an information source. In this paper we introduce the 'Layout-Aware PDF Text Extraction' (LA-PDFText) system to facilitate accurate extraction of text from PDF files of research articles for use in text mining applications. Our paper describes the construction and performance of an open source system that extracts text blocks from PDF-formatted full-text research articles and classifies them into logical units based on rules that characterize specific sections. The LA-PDFText system focuses only on the textual content of the research articles and is meant as a baseline for further experiments into more advanced extraction methods that handle multi-modal content, such as images and graphs. The system works in a three-stage process: (1) Detecting contiguous text blocks using spatial layout processing to locate and identify blocks of contiguous text, (2) Classifying text blocks into rhetorical categories using a rule-based method and (3) Stitching classified text blocks together in the correct order resulting in the extraction of text from section-wise grouped blocks. We show that our system can identify text blocks and classify them into rhetorical categories with Precision1 = 0.96% Recall = 0.89% and F1 = 0.91%. We also present an evaluation of the accuracy of the block detection algorithm used in step 2. Additionally, we have compared the accuracy of the text extracted by LA-PDFText to the text from the Open Access subset of PubMed Central. We then compared this accuracy with that of the text extracted by the PDF2Text system, 2commonly used to extract text from PDF. Finally, we discuss preliminary error analysis for

  9. Layout-aware text extraction from full-text PDF of scientific articles

    PubMed Central

    2012-01-01

    Background The Portable Document Format (PDF) is the most commonly used file format for online scientific publications. The absence of effective means to extract text from these PDF files in a layout-aware manner presents a significant challenge for developers of biomedical text mining or biocuration informatics systems that use published literature as an information source. In this paper we introduce the ‘Layout-Aware PDF Text Extraction’ (LA-PDFText) system to facilitate accurate extraction of text from PDF files of research articles for use in text mining applications. Results Our paper describes the construction and performance of an open source system that extracts text blocks from PDF-formatted full-text research articles and classifies them into logical units based on rules that characterize specific sections. The LA-PDFText system focuses only on the textual content of the research articles and is meant as a baseline for further experiments into more advanced extraction methods that handle multi-modal content, such as images and graphs. The system works in a three-stage process: (1) Detecting contiguous text blocks using spatial layout processing to locate and identify blocks of contiguous text, (2) Classifying text blocks into rhetorical categories using a rule-based method and (3) Stitching classified text blocks together in the correct order resulting in the extraction of text from section-wise grouped blocks. We show that our system can identify text blocks and classify them into rhetorical categories with Precision1 = 0.96% Recall = 0.89% and F1 = 0.91%. We also present an evaluation of the accuracy of the block detection algorithm used in step 2. Additionally, we have compared the accuracy of the text extracted by LA-PDFText to the text from the Open Access subset of PubMed Central. We then compared this accuracy with that of the text extracted by the PDF2Text system, 2commonly used to extract text from PDF. Finally, we discuss

  10. Delimitation and management of emerald ash borer (Coleoptera: Buprestidae) at an outlier infestation in southwestern New York State, United States of America: case study

    USDA-ARS?s Scientific Manuscript database

    Research objectives were to develop an adaptive delimitation technique and to implement and evaluate management of emerald ash borer (EAB) Agrilus planipennis in the first infestation discovered in New York State. Delimitation was accomplished using 91 girdled “sentinel” trap trees deployed up to 1...

  11. Testing of the Trim Tab Parametric Model in NASA Langley's Unitary Plan Wind Tunnel

    NASA Technical Reports Server (NTRS)

    Murphy, Kelly J.; Watkins, Anthony N.; Korzun, Ashley M.; Edquist, Karl T.

    2013-01-01

    In support of NASA's Entry, Descent, and Landing technology development efforts, testing of Langley's Trim Tab Parametric Models was conducted in Test Section 2 of NASA Langley's Unitary Plan Wind Tunnel. The objectives of these tests were to generate quantitative aerodynamic data and qualitative surface pressure data for experimental and computational validation and aerodynamic database development. Six component force-and-moment data were measured on 38 unique, blunt body trim tab configurations at Mach numbers of 2.5, 3.5, and 4.5, angles of attack from -4deg to +20deg, and angles of sideslip from 0deg to +8deg. Configuration parameters investigated in this study were forebody shape, tab area, tab cant angle, and tab aspect ratio. Pressure Sensitive Paint was used to provide qualitative surface pressure mapping for a subset of these flow and configuration variables. Over the range of parameters tested, the effects of varying tab area and tab cant angle were found to be much more significant than varying tab aspect ratio relative to key aerodynamic performance requirements. Qualitative surface pressure data supported the integrated aerodynamic data and provided information to aid in future analyses of localized phenomena for trim tab configurations.

  12. Parametric Study and Design of Tab Shape for Improving Aerodynamic Performance of Rotor Blade

    NASA Astrophysics Data System (ADS)

    Han, Jaeseong; Kwon, Oh Joon

    2018-04-01

    In the present study, the parametric study was performed to analyze the effect of the tab on the aerodynamic performance and characteristics of rotor blades. Also, the tab shape was designed to improve the aerodynamic performance of rotor blades. A computational fluid dynamics solver based on three-dimensional Reynolds averaged Navier-Stokes equation using an unstructured mesh was used for the parametric study and the tab design. For airfoils, the effect of length and angle of a tab was studied on the aerodynamic characteristics of airfoils. In addition, including those parameters, the effect of a span of a tab was studied for rotor blades in hovering flight. The results of the parametric study were analyzed in terms of change of the aerodynamic performance and characteristics to understand the effect of a tab. Considering the analysis, the design of tab shape was conducted to improve the aerodynamic performance of rotor blades. The simply attached tab to trailing edge of the rotor blades increases the thrust of the rotor blades without significant changing of aerodynamic characteristics of the rotor blades in hovering and forward flight.

  13. Titania/CnTAB Nanoskeleton as adsorbent and photocatalyst for removal of alkylphenols dissolved in water.

    PubMed

    Sakai, Toshio; Da Loves, Albar; Okada, Tomohiko; Mishima, Shozi

    2013-03-15

    We report here on the removal of alkylphenols (phenol, 4-n-propylphenol, 4-n-heptylphenol and 4-nonylphenol) dissolved in water using the composite particles of nanocrystalline titania and alkyltrimethylammonium bromide (CnH2n+1N(CH3)3Br, CnTAB; n=12, 14, 16 and 18) (named as TiO2/CnTAB Nanoskeleton) as adsorbents and photocatalysts. In particular, the adsorption of alkylphenols onto TiO2/CnTAB Nanoskeleton in water was investigated in terms of hydrophobic interaction between alkylphenols and CnTAB, surface area, pore structure and crystal size of TiO2/CnTAB Nanoskeleton. We revealed that CnTAB incorporated in the TiO2/CnTAB Nanoskeleton promotes the adsorption of alkylphenols onto TiO2/CnTAB Nanoskeleton due to the hydrophobic interaction between alkylphenols and CnTAB. On the other hand, the surface area, pore structure and crystal size of TiO2/CnTAB Nanoskeleton did not affect the adsorption of alkylphenols onto TiO2/CnTAB Nanoskeleton. We also found that the alkylphenols dissolved in water were completely removed by the combination of adsorption and photocatalytic degradation by the TiO2/CnTAB Nanoskeleton under UV irradiation. These results prove that the TiO2/CnTAB Nanoskeleton acts as in tandem an adsorbent and a photocatalyst for removal of alkylphenols dissolved in water. Copyright © 2013 Elsevier B.V. All rights reserved.

  14. Eddy-Current Inspection Of Tab Seals On Beverage Cans

    NASA Technical Reports Server (NTRS)

    Bar-Cohen, Yoseph

    1994-01-01

    Eddy-current inspection system monitors tab seals on beverage cans. Device inspects all cans at usual production rate of 1,500 to 2,000 cans per minute. Automated inspection of all units replaces visual inspection by microscope aided by mass spectrometry. System detects defects in real time. Sealed cans on conveyor pass near one of two coils in differential eddy-current probe. Other coil in differential eddy-current probe positioned near stationary reference can on which tab seal is known to be of acceptable quality. Signal of certain magnitude at output of probe indicates defective can, automatically ejected from conveyor.

  15. Southern California Earthquake Center Geologic Vertical Motion Database

    NASA Astrophysics Data System (ADS)

    Niemi, Nathan A.; Oskin, Michael; Rockwell, Thomas K.

    2008-07-01

    The Southern California Earthquake Center Geologic Vertical Motion Database (VMDB) integrates disparate sources of geologic uplift and subsidence data at 104- to 106-year time scales into a single resource for investigations of crustal deformation in southern California. Over 1800 vertical deformation rate data points in southern California and northern Baja California populate the database. Four mature data sets are now represented: marine terraces, incised river terraces, thermochronologic ages, and stratigraphic surfaces. An innovative architecture and interface of the VMDB exposes distinct data sets and reference frames, permitting user exploration of this complex data set and allowing user control over the assumptions applied to convert geologic and geochronologic information into absolute uplift rates. Online exploration and download tools are available through all common web browsers, allowing the distribution of vertical motion results as HTML tables, tab-delimited GIS-compatible text files, or via a map interface through the Google Maps™ web service. The VMDB represents a mature product for research of fault activity and elastic deformation of southern California.

  16. Multilocus Phylogeography and Species Delimitation in the Cumberland Plateau Salamander, Plethodon kentucki: Incongruence among Data Sets and Methods

    PubMed Central

    Kuchta, Shawn R.; Brown, Ashley D.; Converse, Paul E.; Highton, Richard

    2016-01-01

    Species are a fundamental unit of biodiversity, yet can be challenging to delimit objectively. This is particularly true of species complexes characterized by high levels of population genetic structure, hybridization between genetic groups, isolation by distance, and limited phenotypic variation. Previous work on the Cumberland Plateau Salamander, Plethodon kentucki, suggested that it might constitute a species complex despite occupying a relatively small geographic range. To examine this hypothesis, we sampled 135 individuals from 43 populations, and used four mitochondrial loci and five nuclear loci (5693 base pairs) to quantify phylogeographic structure and probe for cryptic species diversity. Rates of evolution for each locus were inferred using the multidistribute package, and time calibrated gene trees and species trees were inferred using BEAST 2 and *BEAST 2, respectively. Because the parameter space relevant for species delimitation is large and complex, and all methods make simplifying assumptions that may lead them to fail, we conducted an array of analyses. Our assumption was that strongly supported species would be congruent across methods. Putative species were first delimited using a Bayesian implementation of the GMYC model (bGMYC), Geneland, and Brownie. We then validated these species using the genealogical sorting index and BPP. We found substantial phylogeographic diversity using mtDNA, including four divergent clades and an inferred common ancestor at 14.9 myr (95% HPD: 10.8–19.7 myr). By contrast, this diversity was not corroborated by nuclear sequence data, which exhibited low levels of variation and weak phylogeographic structure. Species trees estimated a far younger root than did the mtDNA data, closer to 1.0 myr old. Mutually exclusive putative species were identified by the different approaches. Possible causes of data set discordance, and the problem of species delimitation in complexes with high levels of population structure and

  17. Experimental and Computational Investigation of Lift-Enhancing Tabs on a Multi-Element Airfoil

    NASA Technical Reports Server (NTRS)

    Ashby, Dale L.

    1996-01-01

    An experimental and computational investigation of the effect of lift-enhancing tabs on a two-element airfoil has been conducted. The objective of the study was to develop an understanding of the flow physics associated with lift-enhancing tabs on a multi-element airfoil. An NACA 63(2)-215 ModB airfoil with a 30% chord fowler flap was tested in the NASA Ames 7- by 10-Foot Wind Tunnel. Lift-enhancing tabs of various heights were tested on both the main element and the flap for a variety of flap riggings. A combination of tabs located at the main element and flap trailing edges increased the airfoil lift coefficient by 11% relative to the highest lift coefficient achieved by any baseline configuration at an angle of attack of 0 deg, and C(sub 1max) was increased by 3%. Computations of the flow over the two-element airfoil were performed using the two-dimensional incompressible Navier-Stokes code INS2D-UP. The computed results predicted all of the trends observed in the experimental data quite well. In addition, a simple analytic model based on potential flow was developed to provide a more detailed understanding of how lift-enhancing tabs work. The tabs were modeled by a point vortex at the air-foil or flap trailing edge. Sensitivity relationships were derived which provide a mathematical basis for explaining the effects of lift-enhancing tabs on a multi-element airfoil. Results of the modeling effort indicate that the dominant effects of the tabs on the pressure distribution of each element of the airfoil can be captured with a potential flow model for cases with no flow separation.

  18. DATALINK. Records Inventory Data Collection Software

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cole, B.

    1995-03-01

    DATALINK was created to provide an easy to use data collection program for records management software products. It provides several useful tools for capturing and validating record index data in the field. It also allows users to easily create a comma delimited, ASCII text file for data export into most records management software products.

  19. Records Inventory Data Collection Software

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cole, Brian A.

    1995-03-01

    DATALINK was created to provide an easy to use data collection program for records management software products. It provides several useful tools for capturing and validating record index data in the field. It also allows users to easily create a comma delimited, ASCII text file for data export into most records management software products.

  20. Effects of phylogenetic reconstruction method on the robustness of species delimitation using single-locus data

    PubMed Central

    Tang, Cuong Q; Humphreys, Aelys M; Fontaneto, Diego; Barraclough, Timothy G; Paradis, Emmanuel

    2014-01-01

    Coalescent-based species delimitation methods combine population genetic and phylogenetic theory to provide an objective means for delineating evolutionarily significant units of diversity. The generalised mixed Yule coalescent (GMYC) and the Poisson tree process (PTP) are methods that use ultrametric (GMYC or PTP) or non-ultrametric (PTP) gene trees as input, intended for use mostly with single-locus data such as DNA barcodes. Here, we assess how robust the GMYC and PTP are to different phylogenetic reconstruction and branch smoothing methods. We reconstruct over 400 ultrametric trees using up to 30 different combinations of phylogenetic and smoothing methods and perform over 2000 separate species delimitation analyses across 16 empirical data sets. We then assess how variable diversity estimates are, in terms of richness and identity, with respect to species delimitation, phylogenetic and smoothing methods. The PTP method generally generates diversity estimates that are more robust to different phylogenetic methods. The GMYC is more sensitive, but provides consistent estimates for BEAST trees. The lower consistency of GMYC estimates is likely a result of differences among gene trees introduced by the smoothing step. Unresolved nodes (real anomalies or methodological artefacts) affect both GMYC and PTP estimates, but have a greater effect on GMYC estimates. Branch smoothing is a difficult step and perhaps an underappreciated source of bias that may be widespread among studies of diversity and diversification. Nevertheless, careful choice of phylogenetic method does produce equivalent PTP and GMYC diversity estimates. We recommend simultaneous use of the PTP model with any model-based gene tree (e.g. RAxML) and GMYC approaches with BEAST trees for obtaining species hypotheses. PMID:25821577

  1. 5 CFR 1201.143 - Right to hearing; filing complaint; serving documents on parties.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Executive Service under 5 U.S.C. 3592(a) (2) and 5 CFR 359.502, and to place that employee in another civil... least 15 days before the effective date of the proposed removal, the request will be granted. (b) Place... must file two copies of the request, together with numbered and tabbed exhibits or attachments, if any...

  2. 5 CFR 1201.143 - Right to hearing; filing complaint; serving documents on parties.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Executive Service under 5 U.S.C. 3592(a) (2) and 5 CFR 359.502, and to place that employee in another civil... least 15 days before the effective date of the proposed removal, the request will be granted. (b) Place... must file two copies of the request, together with numbered and tabbed exhibits or attachments, if any...

  3. Effect of Delta Tabs on Free Jets from Complex Nozzles

    NASA Technical Reports Server (NTRS)

    Zaman, K. B. M. Q.

    2001-01-01

    Effects of 'delta-tabs' on the mixing and noise characteristics of two model-scale nozzles have been investigated experimentally. The two models are (1) an eight-lobed nozzle simulating the primary flow of a mixer-ejector configuration considered for the HSCT program, (2) an axisymmetric nozzle with a centerbody simulating the 'ACE' configuration also considered for the HSCT program. Details of the flow-field for model (1) are explored, while primarily the noise-field is explored for model (2). Effects of different tab configurations are documented.

  4. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Phillion, D.

    This code enables one to display, take line-outs on, and perform various transformations on an image created by an array of integer*2 data. Uncompressed eight-bit TIFF files created on either the Macintosh or the IBM PC may also be read in and converted to a 16 bit signed integer image. This code is designed to handle all the formats used for PDS (photo-densitometer) files at the Lawrence Livermore National Laboratory. These formats are all explained by the application code. The image may be zoomed infinitely and the gray scale mapping can be easily changed. Line-outs may be horizontal or verticalmore » with arbitrary width, angled with arbitrary end points, or taken along any path. This code is usually used to examine spectrograph data. Spectral lines may be identified and a polynomial fit from position to wavelength may be found. The image array can be remapped so that the pixels all have the same change of lambda width. It is not necessary to do this, however. Lineouts may be printed, saved as Cricket tab-delimited files, or saved as PICT2 files. The plots may be linear, semilog, or logarithmic with nice values and proper scientific notation. Typically, spectral lines are curved.« less

  5. An Experimental Study of the Near Field Region of a Free Jet with Passive Mixing Tabs

    NASA Technical Reports Server (NTRS)

    Bohl, D. G.; Foss, J. F.

    1997-01-01

    An experimental study was performed to determine the flow characteristics of a tabbed free jet. Results were acquired in the near field (nominally 2 tab widths upstream to 2 tab widths downstream of the exit plane) of a tabbed jet. Upstream pressure results showed static pressure distributions in both the x-and y-directions along the top surface of the tunnel. Hot-wire measurements showed rapid expansion of the core fluid into the ambient region. Two counter rotating regions of streamwise vorticity were shown on each side of the primary tab. An enhancement of the tabbed jet concept was proposed and tested. Specifically, two tabs, half the scale of the primary tab, were added to the primary tab to provide attachment surfaces for the normally occurring ejection of fluid. The secondary tabs caused a slight increase in the streamwise vorticity created from the upstream static pressure gradient while significantly increasing the re-oriented boundary layer vorticity. The combined pumping effect of the two counter rotating regions of vorticity caused a significant increase in the transport of the jet core fluid into the surrounding region.

  6. Investigations on the stability, oscillation, and stress conditions of airplanes with tab control. Second partial report : application of the solutions obtained in the first partial report to tab-controlled airplanes.

    NASA Technical Reports Server (NTRS)

    Filzek, B

    1949-01-01

    The first partial report, FB 2000, contained a discussion of the derivation of the equations of motion and their solutions for a tab-controlled airplane; the results obtained there are now to be applied to the longitudinal motion of tab-controlled airplanes. In view of the abundance of structural factors and aerodynamic parameters, a general discussion of the problems is unfeasible. Thus it is demonstrated on the basis of examples what stability, oscillation, and stress conditions are to be expected for tab-controlled airplanes. (author)

  7. A criterion for delimiting active periods within turbulent flows

    NASA Astrophysics Data System (ADS)

    Keylock, C. J.

    2008-06-01

    Delimiting effectively the extent of the major motions in atmospheric, tidal and fluvial turbulent flows is an important task for studies of mixing and particle transport. The most common method for this (quadrant analysis) is closely linked to the turbulent stresses but subdivides active periods in the flow into separate events. A method based on the pointwise Hölder characteristics of the velocity data is introduced in this paper and applied to extract the whole duration of the active periods, within which turbulence intensities and stresses are high for some of the time. The cross-correlation structure of the Hölder series permits a simple threshold to be adopted. The technique is tested on data from a turbulent wake in a wind tunnel and flow over a forest canopy.

  8. PSTOOLS - FOUR PROGRAMS THAT INTERPRET/FORMAT POSTSCRIPT FILES

    NASA Technical Reports Server (NTRS)

    Choi, D.

    1994-01-01

    PSTOOLS is a package of four programs that operate on files written in the page description language, PostScript. The programs include a PostScript previewer for the IRIS workstation, a PostScript driver for the Matrix QCRZ film recorder, a PostScript driver for the Tektronix 4693D printer, and a PostScript code beautifier that formats PostScript files to be more legible. The three programs PSIRIS, PSMATRIX, and PSTEK are similar in that they all interpret the PostScript language and output the graphical results to a device, and they support color PostScript images. The common code which is shared by these three programs is included as a library of routines. PSPRETTY formats a PostScript file by appropriately indenting procedures and code delimited by "saves" and "restores." PSTOOLS does not use Adobe fonts. PSTOOLS is written in C-language for implementation on SGI IRIS 4D series workstations running IRIX 3.2 or later. A README file and UNIX man pages provide information regarding the installation and use of the PSTOOLS programs. A six-page manual which provides slightly more detailed information may be purchased separately. The standard distribution medium for this package is one .25 inch streaming magnetic tape cartridge in UNIX tar format. PSIRIS (the largest program) requires 1.2Mb of main memory. PSMATRIX requires the "gpib" board (IEEE 488) available from Silicon Graphics. Inc. The programs with graphical interfaces require that the IRIS have at least 24 bit planes. This package was developed in 1990 and updated in 1991. SGI, IRIS 4D, and IRIX are trademarks of Silicon Graphics, Inc. Matrix QCRZ is a registered trademark of the AGFA Group. Tektronix 4693D is a trademark of Tektronix, Inc. Adobe is a trademark of Adobe Systems Incorporated. PostScript is a registered trademark of Adobe Systems Incorporated. UNIX is a registered trademark of AT&T Bell Laboratories.

  9. Species delimitation in plants using the Qinghai–Tibet Plateau endemic Orinus (Poaceae: Tridentinae) as an example

    PubMed Central

    Su, Xu; Wu, Guili; Li, Lili; Liu, Jianquan

    2015-01-01

    Background and Aims Accurate identification of species is essential for the majority of biological studies. However, defining species objectively and consistently remains a challenge, especially for plants distributed in remote regions where there is often a lack of sufficient previous specimens. In this study, multiple approaches and lines of evidence were used to determine species boundaries for plants occurring in the Qinghai–Tibet Plateau, using the genus Orinus (Poaceae) as a model system for an integrative approach to delimiting species. Methods A total of 786 individuals from 102 populations of six previously recognized species were collected for niche, morphological and genetic analyses. Three plastid DNA regions (matK, rbcL and trnH-psbA) and one nuclear DNA region [internal transcribed space (ITS)] were sequenced. Key Results Whereas six species had been previously recognized, statistical analyses based on character variation, molecular data and niche differentiation identified only two well-delimited clusters, together with a third possibly originating from relatively recent hybridization between, or historical introgression from, the other two. Conclusions Based on a principle of integrative species delimitation to reconcile different sources of data, the results provide compelling evidence that the six previously recognized species of the genus Orinus that were examined should be reduced to two, with new circumscriptions, and a third, identified in this study, should be described as a new species. This empirical study highlights the value of applying genetic differentiation, morphometric statistics and ecological niche modelling in an integrative approach to re-circumscribing species boundaries. The results produce relatively objective, operational and unbiased taxonomic classifications of plants occurring in remote regions. PMID:25987712

  10. glopara files

    Science.gov Websites

    prepbufr BUFR biascr.$CDUMP.$CDATE Time dependent sat bias correction file abias text satang.$CDUMP.$CDATE Angle dependent sat bias correction satang text sfcanl.$CDUMP.$CDATE surface analysis sfcanl binary tcvitl.$CDUMP.$CDATE Tropical Storm Vitals syndata.tcvitals.tm00 text adpsfc.$CDUMP.$CDATE Surface land

  11. A Python library for FAIRer access and deposition to the Metabolomics Workbench Data Repository.

    PubMed

    Smelter, Andrey; Moseley, Hunter N B

    2018-01-01

    The Metabolomics Workbench Data Repository is a public repository of mass spectrometry and nuclear magnetic resonance data and metadata derived from a wide variety of metabolomics studies. The data and metadata for each study is deposited, stored, and accessed via files in the domain-specific 'mwTab' flat file format. In order to improve the accessibility, reusability, and interoperability of the data and metadata stored in 'mwTab' formatted files, we implemented a Python library and package. This Python package, named 'mwtab', is a parser for the domain-specific 'mwTab' flat file format, which provides facilities for reading, accessing, and writing 'mwTab' formatted files. Furthermore, the package provides facilities to validate both the format and required metadata elements of a given 'mwTab' formatted file. In order to develop the 'mwtab' package we used the official 'mwTab' format specification. We used Git version control along with Python unit-testing framework as well as continuous integration service to run those tests on multiple versions of Python. Package documentation was developed using sphinx documentation generator. The 'mwtab' package provides both Python programmatic library interfaces and command-line interfaces for reading, writing, and validating 'mwTab' formatted files. Data and associated metadata are stored within Python dictionary- and list-based data structures, enabling straightforward, 'pythonic' access and manipulation of data and metadata. Also, the package provides facilities to convert 'mwTab' files into a JSON formatted equivalent, enabling easy reusability of the data by all modern programming languages that implement JSON parsers. The 'mwtab' package implements its metadata validation functionality based on a pre-defined JSON schema that can be easily specialized for specific types of metabolomics studies. The library also provides a command-line interface for interconversion between 'mwTab' and JSONized formats in raw text and a

  12. In-flight tracking of helicopter rotor blades with tabs using shape memory alloy actuators

    NASA Astrophysics Data System (ADS)

    Epps, Jeanette Jo

    The objective of this research is to develop a methodology to track helicopter rotor blades in-flight with tabs using shape memory alloy actuators. Tracking is required to reduce vibratory loads that are generated due to dissimilarity of blades. The research was conducted in two phases. The first phase involved a study on the thermo-mechanical behavior of shape memory alloys and the development of an analytical model to describe the behavior of the tab actuator (SMA-SMA actuator). The second phase of the research involved applying the knowledge of the SMA behavior to develop, construct and test a tab actuator to deflect a trailing-edge tab. In the first phase, four constitutive models for SMA were investigated and validated with test data. The models investigated were the Tanaka, Liang and Rogers, Brinson, and Boyd and Lagoudas models. These models were used to predict the quasi-static stress-strain-temperature behavior. All models showed acceptable correlation with test data. Then a constrained recovery model was developed for the case where the SMA wire is plastically deformed, clamped at both ends, and then heat activated. The Brinson model over-predicted the recovery stress-temperature behavior. The refined model developed in this dissertation showed acceptable correlation with test data. In the second phase of the research, a NACA 0012 blade section with a tab actuator embedded was constructed. The actuator was tested on bench-top as well as in an open-jet wind tunnel to determine the actuator performance under different flight conditions. This task also included building and testing a locking mechanism and a position feedback controller. It was shown that a 2-wire actuator, with all wires plastically elongated to 4.21% initially, is able to deflect the tab of a blade section sufficiently at a forward velocity of 120 ft/sec for angles of attack up to 15°. The tab deflected up 9.35° and deflected down 31°. A 5-wire actuator with all wires plastically

  13. DATALINK: Records inventory data collection software. User`s guide

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cole, B.A.

    1995-03-01

    DATALINK was created to provide an easy to use data collection program for records management software products. It provides several useful tools for capturing and validating record index data in the field. It also allows users to easily create a comma delimited, ASCII text file for data export into most records management software products. It runs on virtually any computer us MS-DOS.

  14. Structural and aerodynamic considerations of an active piezoelectric trailing-edge tab on a helicopter rotor

    NASA Astrophysics Data System (ADS)

    Murray, Gabriel Jon

    This dissertation is concerned with an active tab for use on a rotorcraft for noise and vibration reduction. The tab is located at the trailing edge of the airfoil. The tab consists of a shim sandwiched by layers of the piezoelectric actuators, macro fiber composites, of varying length. This configuration is similar to a bimorph. The modus operandi is similar to that of a trailing edge flap. The actuators deform the tab, bending it to achieve a tip displacement. This provides a change in the lift, moment, and drag coefficients of the airfoil. By actuating the system at 3/rev to 5/rev, reductions in noise and vibration can be realized. The system was examined and designed around using the UH-60 Blackhawk as the model rotorcraft. The tab is envisioned to operate between 65% to 85% of the main rotor span. The tab's chordwise dimensions considered were 20% and 15% of the blade chord. In order to assess the potential of the tab to change the lift and moment coefficients of the airfoil-tab system, a steady computational fluid dynamics study was conducted. The results were generated via the University of Maryland's Transonic Unsteady Navier-Stokes code. Various tab deflection angles, Mach numbers, and angle-of-attack values were computed. These results were compared to a trailing edge flap of similar size. The comparison shows that the tab produces lift and moment increments similar to that of the trailing edge flap. The design of the tab---composed of both active piezoelectric actuators and passive materials---was conducted using finite element analysis. The objectives were to maximize the tip deflection due to the actuators, while minimizing the deformation due to inertial and aerodynamic forces and loads. The inertial loads (acceleration terms) come from both blade motion, such as flapping and pitch, as well as the rotation of the rotor (centrifugal force). All of these previously mentioned terms cause the tab to undergo undesirable deflections. The original concept

  15. Molecular species delimitation methods and population genetics data reveal extensive lineage diversity and cryptic species in Aglaopheniidae (Hydrozoa).

    PubMed

    Postaire, Bautisse; Magalon, Hélène; Bourmaud, Chloé A-F; Bruggemann, J Henrich

    2016-12-01

    A comprehensive inventory of global biodiversity would be greatly improved by automating methods for species delimitation. The Automatic Barcode Gap Discovery method, the Poisson tree processes algorithm and the Generalized mixed Yule-coalescent model have been proposed as means of increasing the rate of biodiversity description using single locus data. We applied these methods to explore the diversity within the Aglaopheniidae, a hydrozoan family with many species widely distributed across tropical and temperate oceans. Our analyses revealed widespread cryptic diversity in this family, almost half of the morpho-species presenting several independent evolutionary lineages, as well as support for cases of synonymy. For two common species of this family, Lytocarpia brevirostris and Macrorhynchia phoenicea, we compared the outputs to clustering analyses based on microsatellite data and to nuclear gene phylogenies. For L. brevirostris, microsatellite data were congruent with results of the species delimitation methods, revealing the existence of two cryptic species with Indo-Pacific distribution. For M. phoenicea, all analyses confirmed the presence of two cryptic species within the South-Western Indian Ocean. Our study suggests that the diversity of Aglaopheniidae might be much higher than assumed, likely related to low dispersal capacities. Sequence-based species delimitation methods seem highly valuable to reveal cryptic diversity in hydrozoans; their application in an integrative framework will be very useful in describing the phyletic diversity of these organisms. Copyright © 2016 Elsevier Inc. All rights reserved.

  16. Sending Foreign Language Word Processor Files over Networks.

    ERIC Educational Resources Information Center

    Feustle, Joseph A., Jr.

    1992-01-01

    Advantages of using online systems are described, and specific techniques for successfully transmitting computer text files are described. Topics covered include Microsoft's Rich TextFile, WordPerfect encoding, text compression, and especially encoding and decoding with UNIX programs. (LB)

  17. Delimiting regulatory sequences of the Drosophila melanogaster Ddc gene.

    PubMed Central

    Hirsh, J; Morgan, B A; Scholnick, S B

    1986-01-01

    We delimited sequences necessary for in vivo expression of the Drosophila melanogaster dopa decarboxylase gene Ddc. The expression of in vitro-altered genes was assayed following germ line integration via P-element vectors. Sequences between -209 and -24 were necessary for normally regulated expression, although genes lacking these sequences could be expressed at 10 to 50% of wild-type levels at specific developmental times. These genes showed components of normal developmental expression, which suggests that they retain some regulatory elements. All Ddc genes lacking the normal immediate 5'-flanking sequences were grossly deficient in larval central nervous system expression. Thus, this upstream region must contain at least one element necessary for this expression. A mutated Ddc gene without a normal TATA boxlike sequence used the normal RNA start points, indicating that this sequences is not required for start point specificity. Images PMID:3099170

  18. Species delimitation in plants using the Qinghai-Tibet Plateau endemic Orinus (Poaceae: Tridentinae) as an example.

    PubMed

    Su, Xu; Wu, Guili; Li, Lili; Liu, Jianquan

    2015-07-01

    Accurate identification of species is essential for the majority of biological studies. However, defining species objectively and consistently remains a challenge, especially for plants distributed in remote regions where there is often a lack of sufficient previous specimens. In this study, multiple approaches and lines of evidence were used to determine species boundaries for plants occurring in the Qinghai-Tibet Plateau, using the genus Orinus (Poaceae) as a model system for an integrative approach to delimiting species. A total of 786 individuals from 102 populations of six previously recognized species were collected for niche, morphological and genetic analyses. Three plastid DNA regions (matK, rbcL and trnH-psbA) and one nuclear DNA region [internal transcribed space (ITS)] were sequenced. Whereas six species had been previously recognized, statistical analyses based on character variation, molecular data and niche differentiation identified only two well-delimited clusters, together with a third possibly originating from relatively recent hybridization between, or historical introgression from, the other two. Based on a principle of integrative species delimitation to reconcile different sources of data, the results provide compelling evidence that the six previously recognized species of the genus Orinus that were examined should be reduced to two, with new circumscriptions, and a third, identified in this study, should be described as a new species. This empirical study highlights the value of applying genetic differentiation, morphometric statistics and ecological niche modelling in an integrative approach to re-circumscribing species boundaries. The results produce relatively objective, operational and unbiased taxonomic classifications of plants occurring in remote regions. © The Author 2015. Published by Oxford University Press on behalf of the Annals of Botany Company. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  19. Delimiting Areas of Endemism through Kernel Interpolation

    PubMed Central

    Oliveira, Ubirajara; Brescovit, Antonio D.; Santos, Adalberto J.

    2015-01-01

    We propose a new approach for identification of areas of endemism, the Geographical Interpolation of Endemism (GIE), based on kernel spatial interpolation. This method differs from others in being independent of grid cells. This new approach is based on estimating the overlap between the distribution of species through a kernel interpolation of centroids of species distribution and areas of influence defined from the distance between the centroid and the farthest point of occurrence of each species. We used this method to delimit areas of endemism of spiders from Brazil. To assess the effectiveness of GIE, we analyzed the same data using Parsimony Analysis of Endemism and NDM and compared the areas identified through each method. The analyses using GIE identified 101 areas of endemism of spiders in Brazil GIE demonstrated to be effective in identifying areas of endemism in multiple scales, with fuzzy edges and supported by more synendemic species than in the other methods. The areas of endemism identified with GIE were generally congruent with those identified for other taxonomic groups, suggesting that common processes can be responsible for the origin and maintenance of these biogeographic units. PMID:25611971

  20. Cytoscape file of chemical networks

    EPA Pesticide Factsheets

    The maximum connectivity scores of pairwise chemical conditions summarized from Cmap results in a file with Cytoscape format (http://www.cytoscape.org/). The figures in the publication were generated from this file. The Cytoscape file is formed from importing the eight text file therein.This dataset is associated with the following publication:Wang , R., A. Biales , N. Garcia-Reyero, E. Perkins, D. Villeneuve, G. Ankley, and D. Bencic. Fish Connectivity Mapping: Linking Chemical Stressors by Their MOA-Driven Transcriptomic Profiles. BMC Genomics. BioMed Central Ltd, London, UK, 17(84): 1-20, (2016).

  1. Development of Geospatial Map Based Portal for Delimitation of Mcd Wards

    NASA Astrophysics Data System (ADS)

    Gupta, A. Kumar Chandra; Kumar, P.; Sharma, P. Kumar

    2017-09-01

    The Geospatial Delhi Limited (GSDL), a Govt. of NCT of Delhi Company formed in order to provide the geospatial information of National Capital Territory of Delhi (NCTD) to the Government of National Capital Territory of Delhi (GNCTD) and its organs such as DDA, MCD, DJB, State Election Department, DMRC etc., for the benefit of all citizens of Government of National Capital Territory of Delhi (GNCTD). This paper describes the development of Geospatial Map based Portal for Delimitation of MCD Wards (GMPDW) and election of 3 Municipal Corporations of NCT of Delhi. The portal has been developed as a map based spatial decision support system (SDSS) for delimitation of MCD Wards and draw of peripheral wards boundaries to planning and management of MCD Election process of State Election Commission, and as an MCD election related information searching tools (Polling Station, MCD Wards and Assembly constituency etc.,) for the citizens of NCTD. The GMPDW is based on Client-Server architecture model. It has been developed using Arc GIS Server 10.0 with .NET (pronounced dot net) technology. The GMPDW is scalable to enterprise SDSS with enterprise Geo Database & Virtual Private Network (VPN) connectivity. Spatial data to GMPDW includes Enumeration Block (EB) and Enumeration Blocks Group (EBG) boundaries of Citizens of Delhi, Assembly Constituency, Parliamentary Constituency, Election District, Landmark locations of Polling Stations & basic amenities (Police Stations, Hospitals, Schools and Fire Stations etc.). GMPDW could help achieve not only the desired transparency and easiness in planning process but also facilitates through efficient & effective tools for management of MCD election. It enables a faster response to the changing ground realities in the development planning, owing to its in-built scientific approach and open-ended design.

  2. A network approach for identifying and delimiting biogeographical regions.

    PubMed

    Vilhena, Daril A; Antonelli, Alexandre

    2015-04-24

    Biogeographical regions (geographically distinct assemblages of species and communities) constitute a cornerstone for ecology, biogeography, evolution and conservation biology. Species turnover measures are often used to quantify spatial biodiversity patterns, but algorithms based on similarity can be sensitive to common sampling biases in species distribution data. Here we apply a community detection approach from network theory that incorporates complex, higher-order presence-absence patterns. We demonstrate the performance of the method by applying it to all amphibian species in the world (c. 6,100 species), all vascular plant species of the USA (c. 17,600) and a hypothetical data set containing a zone of biotic transition. In comparison with current methods, our approach tackles the challenges posed by transition zones and succeeds in retrieving a larger number of commonly recognized biogeographical regions. This method can be applied to generate objective, data-derived identification and delimitation of the world's biogeographical regions.

  3. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Phillion, D.

    This code enables one to display, take line-outs on, and perform various transformations on an image created by an array of integer*2 data. Uncompressed eight-bit TIFF files created on either the Macintosh or the IBM PC may also be read in and converted to a 16 bit signed integer image. This code is designed to handle all the formates used for PDS (photo-densitometer) files at the Lawrence Livermore National Laboratory. These formats are all explained by the application code. The image may be zoomed infinitely and the gray scale mapping can be easily changed. Line-outs may be horizontal or verticalmore » with arbitrary width, angled with arbitrary end points, or taken along any path. This code is usually used to examine spectrograph data. Spectral lines may be identified and a polynomial fit from position to wavelength may be found. The image array can be remapped so that the pixels all have the same change of lambda width. It is not necessary to do this, however. Lineouts may be printed, saved as Cricket tab-delimited files, or saved as PICT2 files. The plots may be linear, semilog, or logarithmic with nice values and proper scientific notation. Typically, spectral lines are curved. By identifying points on these lines and fitting their shapes by polyn.« less

  4. Text Exchange System

    NASA Technical Reports Server (NTRS)

    Snyder, W. V.; Hanson, R. J.

    1986-01-01

    Text Exchange System (TES) exchanges and maintains organized textual information including source code, documentation, data, and listings. System consists of two computer programs and definition of format for information storage. Comprehensive program used to create, read, and maintain TES files. TES developed to meet three goals: First, easy and efficient exchange of programs and other textual data between similar and dissimilar computer systems via magnetic tape. Second, provide transportable management system for textual information. Third, provide common user interface, over wide variety of computing systems, for all activities associated with text exchange.

  5. Data Compression in Full-Text Retrieval Systems.

    ERIC Educational Resources Information Center

    Bell, Timothy C.; And Others

    1993-01-01

    Describes compression methods for components of full-text systems such as text databases on CD-ROM. Topics discussed include storage media; structures for full-text retrieval, including indexes, inverted files, and bitmaps; compression tools; memory requirements during retrieval; and ranking and information retrieval. (Contains 53 references.)…

  6. Flight Measurements to Determine Effect of a Spring-Loaded Tab on Longitudinal Stability of an Airplane

    NASA Technical Reports Server (NTRS)

    Hunter, Paul A.; Reeder, John P.

    1946-01-01

    In conjunction with a program of research on the general problem of stability of airplanes in the climbing condition, tests have been made of a spring-loaded tb which. is referred to as a ?springy tab,? installed on the elevator of a low-wing scout bomber. The tab was arranged to deflect upward with decrease in speed which caused an increase in the pull force required to trim at low speeds and thereby increased the stick-free static longitudinal stability of the airplane. It was found that the springy tab would increase the stick-free stability in all flight conditions, would reduce the danger of inadvertent stalling because of the definite pull force required to stall the airplane with power on, would reduce the effect of center-of-gravity position on stick-free static stability, and would have little effect on the elevator stick forces in accelerated f11ght. Another advantage of the springy tab is that it might be used to provide almost any desired variation of elevator stick force with speed by adjusting the tab hinge-moment characteristics and the variation of spring moment with tab deflection. Unlike the bungee and the bobweight, the springy tab would provide stick-free static stability without requiring a pull force to hold the stick back while taxying. A device similar to the springy tab may be used on the rudder or ailerons to eliminate undesirable trim-force variations with speed.

  7. Species delimitation of the Hyphydrus ovatus complex in western Palaearctic with an update of species distributions (Coleoptera, Dytiscidae)

    PubMed Central

    Bergsten, Johannes; Weingartner, Elisabeth; Hájek, Jiří

    2017-01-01

    Abstract The species status of Hyphydrus anatolicus Guignot, 1957 and H. sanctus Sharp, 1882, previously often confused with the widespread H. ovatus (Linnaeus, 1760), are tested with molecular and morphological characters. Cytochrome c oxidase subunit 1 (CO1) was sequenced for 32 specimens of all three species. Gene-trees were inferred with parsimony, time-free bayesian and strict clock bayesian analyses. The GMYC model was used to estimate species limits. All three species were reciprocally monophyletic with CO1 and highly supported. The GMYC species delimitation analysis unequivocally delimited the three species with no other than the three species solution included in the confidence interval. A likelihood ratio test rejected the one-species null model. Important morphological characters distinguishing the species are provided and illustrated. New distributional data are given for the following species: Hyphydrus anatolicus from Slovakia and Ukraine, and H. aubei Ganglbauer, 1891, and H. sanctus from Turkey. PMID:28769697

  8. Effect of a delta tab on fine scale mixing in a turbulent two-stream shear layer

    NASA Technical Reports Server (NTRS)

    Foss, J. K.; Zaman, K. B. M. Q.

    1996-01-01

    The fine scale mixing produced by a delta tab in a shear layer has been studied experimentally. The tab was placed at the trailing edge of a splitter plate which produced a turbulent two-stream mixing layer. The tab apex tilted downstream and into the high speed stream. Hot-wire measurements in the 3-D space behind the tab detailed the three velocity components as well as the small scale population distributions. These small scale eddies, which represent the peak in the dissipation spectrum, were identified and counted using the Peak-Valley-Counting technique. It was found that the small scale populations were greater in the shear region behind the tab, with the greatest increase occurring where the shear layer underwent a sharp turn. This location was near, but not coincident, with the core of the streamwise vortex, and away from the region exhibiting maximum turbulence intensity. Moreover, the tab increased the most probably frequency and strain rate of the small scales. It made the small scales smaller and more energetic.

  9. 48 CFR 1552.211-75 - Working files.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Working files. 1552.211-75... FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of Provisions and Clauses 1552.211-75 Working.... Working Files (APR 1984) The Contractor shall maintain accurate working files (by task or work assignment...

  10. A new approach to species delimitation in Septoria

    PubMed Central

    Verkley, G.J.M.; Quaedvlieg, W.; Shin, H.-D.; Crous, P.W.

    2013-01-01

    Septoria is a large genus of asexual morphs of Ascomycota causing leaf spot diseases of many cultivated and wild plants. Host specificity has long been a decisive criterium in species delimitation in Septoria, mainly because of the paucity of useful morphological characters and the high level of variation therein. This study aimed at improving the species delimitation of Septoria by adopting a polyphasic approach, including multilocus DNA sequencing and morphological analyses on the natural substrate and in culture. To this end 365 cultures preserved in CBS, Utrecht, The Netherlands, among which many new isolates obtained from fresh field specimens were sequenced. Herbarium material including many types was also studied. Full descriptions of the morphology in planta and in vitro are provided for 57 species. DNA sequences were generated for seven loci, viz. nuclear ITS and (partial) LSU ribosomal RNA genes, RPB2, actin, calmodulin, Btub, and EF. The robust phylogeny inferred showed that the septoria-like fungi are distributed over three main clades, establishing the genera Septoria s. str., Sphaerulina, and Caryophylloseptoria gen. nov. Nine new combinations and one species, Sphaerulina tirolensis sp. nov. were proposed. It is demonstrated that some species have wider host ranges than expected, including hosts from more than one family. Septoria protearum, previously only associated with Proteaceae was found to be also associated with host plants from six additional families of phanerogams and cryptogams. To our knowledge this is the first study to provide DNA-based evidence that multiple family-associations occur for a single species in Septoria. The distribution of host families over the phylogenetic tree showed a highly dispersed pattern for 10 host plant families, providing new insight into the evolution of these fungi. It is concluded that trans-family host jumping is a major force driving the evolution of Septoria and Sphaerulina. Taxonomic novelties: New

  11. Photovoltaic sheathing element with one or more tabs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Keenihan, James R; Langmaid, Joseph A; Lopez, Leonardo C.

    2017-02-07

    The present invention is premised upon an assembly that includes at least a photovoltaic sheathing element capable of being affixed on a building structure. The shingle including at least a photovoltaic cell assembly, a body portion attached to one or more portions of the photovoltaic cell assembly. Wherein the body portion includes one or more top peripheral tabs each capable of fitting under one or more vertically adjoining devices.

  12. Using delimiting surveys to characterize the spatiotemporal dynamics facilitates the management of an invasive non-native insect

    Treesearch

    Patrick C. Tobin; Laura M. Blackburn; Rebecca H. Gray; Christopher T. Lettau; Andrew M. Liebhold; Kenneth F. Raffa

    2013-01-01

    The ability to ascertain abundance and spatial extent of a nascent population of a non-native species can inform management decisions. Following initial detection, delimiting surveys, which involve the use of a finer network of samples around the focal point of a newly detected colony, are often used to quantify colony size, spatial extent, and the location of the...

  13. Delimitation of essential genes of cassava latent virus DNA 2.

    PubMed Central

    Etessami, P; Callis, R; Ellwood, S; Stanley, J

    1988-01-01

    Insertion and deletion mutagenesis of both extended open reading frames (ORFs) of cassava latent virus DNA 2 destroys infectivity. Infectivity is restored by coinoculating constructs that contain single mutations within different ORFs. Although frequent intermolecular recombination produces dominant parental-type virus, mutants can be retained within the virus population indicating that they are competent for replication and suggesting that rescue can occur by complementation of trans acting gene products. By cloning specific fragments into DNA 1 coat protein deletion vectors we have delimited the DNA 2 coding regions and provide substantive evidence that both are essential for virus infection. Although a DNA 2 component is unique to whitefly-transmitted geminiviruses, the results demonstrate that neither coding region is involved solely in insect transmission. The requirement for a bipartite genome for whitefly-transmitted geminiviruses is discussed. Images PMID:3387209

  14. Molecular species delimitation and its implications for species descriptions using desmosomatid and nannoniscid isopods from the VEMA fracture zone as example taxa

    NASA Astrophysics Data System (ADS)

    Brix, Saskia; Bober, Simon; Tschesche, Claudia; Kihara, Terue-Cristina; Driskell, Amy; Jennings, Robert M.

    2018-02-01

    We found 72 species for COI and 45 for 16 S by species delimitation among 186 (from 195 extracted) desmosomatid (144) and nannoniscid (42) sequenced specimens of a total of > 400 specimens for both families. Multiple "discovery"-type species delimitation methods were used, so that consistency across methods could be assessed: The ABGD analysis detected a barcode gap of 3-6% for COI and 4-6% for 16 S, in the whole dataset. Most putative species have a horizontally limited distribution along the Vema fracture zone, although the details depend in part on the interpretation of species delimitation analyses. Putative species were mostly restricted to the eastern or western Vema fracture zone, with only eight crossing the complete Vema fracture zone. Our data suggest that even robustly-sampled species exhibited small ranges; the range estimates calculable from present data were around 500 km, and three were on the order of 1000-2500 km. We chose an abundant, but geographically restricted species (Eugerdella egoni Tschesche and Brix sp. nov.) collected at a single site in the Vema transform fault, and two species (Prochelator barnacki Bober and Brix sp. nov. and Whoia sockei Brix and Kihara sp. nov.) with a broad, but disjunct distribution in the Vema fracture zone for taxonomic description.

  15. Full-text, Downloading, & Other Issues.

    ERIC Educational Resources Information Center

    Tenopir, Carol

    1983-01-01

    Issues having a possible impact on online search services in libraries are discussed including full text databases, front-end processors which translate user's input into the command language of an appropriate system, downloading to create personal files from commercial databases, and pricing. (EJS)

  16. 25 CFR 542.8 - What are the minimum internal control standards for pull tabs?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... the accuracy of the ending balance in the pull tab control by reconciling the pull tabs on hand. (6) A.... (g) Standards for statistical reports. (1) Records shall be maintained, which include win, write (sales), and a win-to-write hold percentage as compared to the theoretical hold percentage derived from...

  17. DOCU-TEXT: A tool before the data dictionary

    NASA Technical Reports Server (NTRS)

    Carter, B.

    1983-01-01

    DOCU-TEXT, a proprietary software package that aids in the production of documentation for a data processing organization and can be installed and operated only on IBM computers is discussed. In organizing information that ultimately will reside in a data dictionary, DOCU-TEXT proved to be a useful documentation tool in extracting information from existing production jobs, procedure libraries, system catalogs, control data sets and related files. DOCU-TEXT reads these files to derive data that is useful at the system level. The output of DOCU-TEXT is a series of user selectable reports. These reports can reflect the interactions within a single job stream, a complete system, or all the systems in an installation. Any single report, or group of reports, can be generated in an independent documentation pass.

  18. Influence of surface layer removal of shade guide tabs on the measured color by spectrophotometer and spectroradiometer.

    PubMed

    Kim, Jin-Cheol; Yu, Bin; Lee, Yong-Keun

    2008-12-01

    To determine the changes in color parameters of Vitapan 3D-Master shade guide tabs by a spectrophotometer (SP) or a spectroradiometer (SR), and by the removal of the surface layer of the tabs that was performed to make a flat measuring surface for the SP color measurement. Color of the shade tabs was measured before and after removing the surface layer of the tabs using SP and SR. Correlations between the color parameters between the original (OR) and the surface layer removed (RM) tabs and between the SP and the SR measurements were determined (alpha=0.05). Based on SP, the lightness, chroma, CIE a* and b* values measured after the surface layer removal were higher than those of the original tabs except a few cases. Based on SR, the chroma and CIE a* and b* values measured after surface layer removal were higher than those of the original tabs except a few cases; however, in case of the lightness, the changes varied by the shade designation. Type of instrument influenced the changes in color parameters based on paired t-test (p<0.05). The color parameters of the OR and RM tabs showed correlations based on both SP and SR measurements (r=0.952-0.997 and p<0.01); however, color difference between the SP-RM and SR-OR tabs was in the range of 18.1-27.0 DeltaE(ab)(*) units (mean: 23.3+/-2.2). When the color of tooth-shaped objects is measured with a spectrophotometer or a spectroradiometer, measurement protocols should be specified because color difference by the surface layer removal and the instrument was high.

  19. The wheat transcription factor, TabHLH39, improves tolerance to multiple abiotic stressors in transgenic plants.

    PubMed

    Zhai, Yiqian; Zhang, Lichao; Xia, Chuan; Fu, Silu; Zhao, Guangyao; Jia, Jizeng; Kong, Xiuying

    2016-05-13

    Although bHLH transcription factors play important roles regulating plant development and abiotic stress response and tolerance, few functional studies have been performed in wheat. In this study, we isolated and characterized a bHLH gene, TabHLH39, from wheat. The TabHLH39 gene is located on wheat chromosome 5DL, and the protein localized to the nucleus and activated transcription. TabHLH39 showed variable expression in roots, stems, leaves, glumes, pistils and stamens and was induced by polyethylene glycol, salt and cold treatments. Further analysis revealed that TabHLH39 overexpression in Arabidopsis significantly enhanced tolerance to drought, salt and freezing stress during the seedling stage, which was also demonstrated by enhanced abiotic stress-response gene expression and changes to several physiological indices. Therefore, TabHLH39 has potential in transgenic breeding applications to improve abiotic stress tolerance in crops. Copyright © 2016 Elsevier Inc. All rights reserved.

  20. Species delimitation of the North American orchard-spider Leucauge venusta (Walckenaer, 1841) (Araneae, Tetragnathidae).

    PubMed

    Ballesteros, Jesús A; Hormiga, Gustavo

    2018-04-01

    The orchard spider, Leucauge venusta (Walckenaer, 1841) is one of the most common and abundant orb-weavers in North America. This species has a broad geographic distribution extending across tropical and temperate regions of the Americas from Canada to Brazil. Guided by a preliminary observation of the barcode gap between sequences from specimens of L. venusta collected in Florida and other North American localities, we collected across a transect through the southeastern USA to investigate the observed genetic divide. The dataset, complemented with additional samples from Mexico, and Brazil was analyzed for species delimitation using STACEY and bGMYC based on sequences from one nuclear (ITS2) and one mitochondrial marker (COI). The analyses clearly separate USA samples into two deeply divergent and geographically structured groups (north-south) which we interpret as two different species. We generated ecological niche models for these two groups rejecting a niche equivalence hypothesis for these lineages. Taxonomic changes are proposed based on these findings, Leucauge venusta is restricted to denote the northern clade, and its known distribution restricted to the USA. Leucauge argyrobapta (White, 1841) is removed from synonymy to denote the populations in Florida, Mexico and Brazil. Although the delimitation analyses suggest each of these geographic clusters within the L. argyrobapta samples represent different species, more specimens from Central and South America are needed to properly test the cohesion of L. argyrobapta populations. Copyright © 2018 Elsevier Inc. All rights reserved.

  1. 25 CFR 543.9 - What are the minimum internal control standards for pull tabs?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false What are the minimum internal control standards for pull tabs? 543.9 Section 543.9 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR HUMAN SERVICES MINIMUM INTERNAL CONTROL STANDARDS FOR CLASS II GAMING § 543.9 What are the minimum internal control standards for pull tabs? (a)...

  2. 25 CFR 542.8 - What are the minimum internal control standards for pull tabs?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false What are the minimum internal control standards for pull tabs? 542.8 Section 542.8 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR HUMAN SERVICES MINIMUM INTERNAL CONTROL STANDARDS § 542.8 What are the minimum internal control standards for pull tabs? (a) Computer applications. For...

  3. 25 CFR 543.9 - What are the minimum internal control standards for pull tabs?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 2 2014-04-01 2014-04-01 false What are the minimum internal control standards for pull tabs? 543.9 Section 543.9 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR HUMAN SERVICES MINIMUM INTERNAL CONTROL STANDARDS FOR CLASS II GAMING § 543.9 What are the minimum internal control standards for pull tabs? (a)...

  4. 25 CFR 542.8 - What are the minimum internal control standards for pull tabs?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 2 2014-04-01 2014-04-01 false What are the minimum internal control standards for pull tabs? 542.8 Section 542.8 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR HUMAN SERVICES MINIMUM INTERNAL CONTROL STANDARDS § 542.8 What are the minimum internal control standards for pull tabs? (a) Computer applications. For...

  5. 25 CFR 542.8 - What are the minimum internal control standards for pull tabs?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 2 2012-04-01 2012-04-01 false What are the minimum internal control standards for pull tabs? 542.8 Section 542.8 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR HUMAN SERVICES MINIMUM INTERNAL CONTROL STANDARDS § 542.8 What are the minimum internal control standards for pull tabs? (a) Computer applications. For...

  6. Aerospell Supplemental Spell Check File

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Aerospell is a supplemental spell check file that can be used as a resource for researchers, writers, editors, students, and others who compose scientific and technical texts. The file extends the general spell check dictionaries of word processors by adding more than 13,000 words used in a broad range of aerospace and related disciplines.

  7. Figure 3

    EPA Pesticide Factsheets

    The Figure.tar.gz contains a directory for each WRF ensemble run. In these directories are *.csv files for each meteorology variable examined. These are comma delimited text files that contain statistics for each observation site. Also provided is an R script that reads these files (user would need to change directory pointers) and computes the variability of error and bias of the ensemble at each site and plots these for reproduction of figure 3.This dataset is associated with the following publication:Gilliam , R., C. Hogrefe , J. Godowitch, S. Napelenok , R. Mathur , and S.T. Rao. Impact of inherent meteorology uncertainty on air quality model predictions. JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES. American Geophysical Union, Washington, DC, USA, 120(23): 12,259–12,280, (2015).

  8. Development and wind tunnel evaluation of a shape memory alloy based trim tab actuator for a civil aircraft

    NASA Astrophysics Data System (ADS)

    Senthilkumar, P.; Jayasankar, S.; Satisha; Sateesh, V. L.; Kamaleshaiah, M. S.; Dayananda, G. N.

    2013-09-01

    This paper presents the development and wind tunnel evaluation of a shape memory alloy (SMA) based smart trim tab for a typical two seater civil aircraft. The SMA actuator was housed in the port side of the elevator for the purpose of actuating the trim tab. Wind tunnel tests were conducted on a full scale horizontal tail model with elevator and trim tab at free stream speeds of 25, 35 and 45 m s-1, and also for a number of deflections of the elevator (30° up, 0° neutral and 25° down) and trim tab (11° and 21° up and 15° and 31° down). To measure the hinge moment experienced by the trim tab under various test conditions, two miniaturized balances were designed and fabricated. A gain scheduled proportional integral (GSPI) controller was developed to control the SMA actuated smart trim tab. It was confirmed during the tests that the trim tab could be controlled at the desired position against the aerodynamic loads acting on it for the various test conditions.

  9. Why species delimitation matters for fungal ecology: Colletotrichum diversity on wild and cultivated cashew in Brazil.

    PubMed

    Veloso, Josiene S; Câmara, Marcos P S; Lima, Waléria G; Michereff, Sami J; Doyle, Vinson P

    2018-07-01

    Anthracnose is one of the most important plant diseases globally, occurring on a wide range of cultivated and wild host species. This study aimed to identify the Colletotrichum species associated with cashew anthracnose in Brazil, determine their phylogenetic relationships and geographical distribution, and provide some insight into the factors that may be influencing community composition. Colletotrichum isolates collected from symptomatic leaves, stems, inflorescences, and fruit of cultivated and wild cashew, across four Brazilian biomes, were identified as Colletotrichum chrysophilum, Colletotrichum fragariae, Colletotrichum fructicola, Colletotrichum gloeosporioides sensu stricto, Colletotrichum queenslandicum, Colletotrichum siamense and Colletotrichum tropicale. Colletotrichum siamense was the most dominant species. The greatest species richness was associated with cultivated cashew; leaves harbored more species than the other organs; the Atlantic Forest encompassed more species than the other biomes; and Pernambuco was the most species-rich location. However, accounting for the relative abundance of Colletotrichum species and differences in sample size across strata, the interpretation of which community is most diverse depends on how species are delimited. The present study provides valuable information about the Colletotrichum/cashew pathosystem, sheds light on the causal agents identification,and highlights the impact that species delimitation can have on ecological studies of fungi. Copyright © 2018 British Mycological Society. Published by Elsevier Ltd. All rights reserved.

  10. Phylogenetic Molecular Species Delimitations Unravel Potential New Species in the Pest Genus Spodoptera Guenée, 1852 (Lepidoptera, Noctuidae)

    PubMed Central

    Dumas, Pascaline; Barbut, Jérôme; Le Ru, Bruno; Silvain, Jean-François; Clamens, Anne-Laure; d’Alençon, Emmanuelle; Kergoat, Gael J.

    2015-01-01

    Nowadays molecular species delimitation methods promote the identification of species boundaries within complex taxonomic groups by adopting innovative species concepts and theories (e.g. branching patterns, coalescence). As some of them can efficiently deal with large single-locus datasets, they could speed up the process of species discovery compared to more time consuming molecular methods, and benefit from the existence of large public datasets; these methods can also particularly favour scientific research and actions dealing with threatened or economically important taxa. In this study we aim to investigate and clarify the status of economically important moths species belonging to the genus Spodoptera (Lepidoptera, Noctuidae), a complex group in which previous phylogenetic analyses and integrative approaches already suggested the possible occurrence of cryptic species and taxonomic ambiguities. In this work, the effectiveness of innovative (and faster) species delimitation approaches to infer putative species boundaries has been successfully tested in Spodoptera, by processing the most comprehensive dataset (in terms of number of species and specimens) ever achieved; results are congruent and reliable, irrespective of the set of parameters and phylogenetic models applied. Our analyses confirm the existence of three potential new species clusters (for S. exigua (Hübner, 1808), S. frugiperda (J.E. Smith, 1797) and S. mauritia (Boisduval, 1833)) and support the synonymy of S. marima (Schaus, 1904) with S. ornithogalli (Guenée, 1852). They also highlight the ambiguity of the status of S. cosmiodes (Walker, 1858) and S. descoinsi Lalanne-Cassou & Silvain, 1994. This case study highlights the interest of molecular species delimitation methods as valuable tools for species discovery and to emphasize taxonomic ambiguities. PMID:25853412

  11. BaCoCa--a heuristic software tool for the parallel assessment of sequence biases in hundreds of gene and taxon partitions.

    PubMed

    Kück, Patrick; Struck, Torsten H

    2014-01-01

    BaCoCa (BAse COmposition CAlculator) is a user-friendly software that combines multiple statistical approaches (like RCFV and C value calculations) to identify biases in aligned sequence data which potentially mislead phylogenetic reconstructions. As a result of its speed and flexibility, the program provides the possibility to analyze hundreds of pre-defined gene partitions and taxon subsets in one single process run. BaCoCa is command-line driven and can be easily integrated into automatic process pipelines of phylogenomic studies. Moreover, given the tab-delimited output style the results can be easily used for further analyses in programs like Excel or statistical packages like R. A built-in option of BaCoCa is the generation of heat maps with hierarchical clustering of certain results using R. As input files BaCoCa can handle FASTA and relaxed PHYLIP, which are commonly used in phylogenomic pipelines. BaCoCa is implemented in Perl and works on Windows PCs, Macs and Linux operating systems. The executable source code as well as example test files and a detailed documentation of BaCoCa are freely available at http://software.zfmk.de. Copyright © 2013 Elsevier Inc. All rights reserved.

  12. Individualized FAC on bottom tab subassemblies to minimize adhesive gap between emitter and optics

    NASA Astrophysics Data System (ADS)

    Sauer, Sebastian; Müller, Tobias; Haag, Sebastian; Beleke, Andreas; Zontar, Daniel; Baum, Christoph; Brecher, Christian

    2017-02-01

    High Power Diode Laser (HPDL) systems with short focal length fast-axis collimators (FAC) require submicron assembly precision. Conventional FAC-Lens assembly processes require adhesive gaps of 50 microns or more in order to compensate for component tolerances (e.g. deviation of back focal length) and previous assembly steps. In order to control volumetric shrinkage of fast-curing UV-adhesives shrinkage compensation is mandatory. The novel approach described in this paper aims to minimize the impact of volumetric shrinkage due to the adhesive gap between HPDL edge emitters and FAC-Lens. Firstly, the FAC is actively aligned to the edge emitter without adhesives or bottom tab. The relative position and orientation of FAC to emitter are measured and stored. Consecutively, an individual subassembly of FAC and bottom tab is assembled on Fraunhofer IPT's mounting station with a precision of +/-1 micron. Translational and lateral offsets can be compensated, so that a narrow and uniform glue gap for the consecutive bonding process of bottom tab to heatsink applies (Figure 4). Accordingly, FAC and bottom tab are mounted to the heatsink without major shrinkage compensation. Fraunhofer IPT's department assembly of optical systems and automation has made several publications regarding active alignment of FAC lenses [SPIE LASE 8241-12], volumetric shrinkage compensation [SPIE LASE 9730-28] and FAC on bottom tab assembly [SPIE LASE 9727-31] in automated production environments. The approach described in this paper combines these and is the logical continuation of that work towards higher quality of HPDLs.

  13. TABS Manual for the Temperament and Atypical Behavior Scale: Early Childhood Indicators of Developmental Dysfunction.

    ERIC Educational Resources Information Center

    Neisworth, John T.; Bagnato, Stephen J.; Salvia, John; Hunt, Frances M.

    This manual describes the rationale, use, and validity of the Temperament and Atypical Behavior Scale (TABS), a norm-referenced measure of dysfunctional behavior appropriately used with infants and young children between the ages of 11 and 71 months. TABS is intended to identify children who are developing atypically or are at risk for atypical…

  14. True lemurs…true species - species delimitation using multiple data sources in the brown lemur complex

    PubMed Central

    2013-01-01

    Background Species are the fundamental units in evolutionary biology. However, defining them as evolutionary independent lineages requires integration of several independent sources of information in order to develop robust hypotheses for taxonomic classification. Here, we exemplarily propose an integrative framework for species delimitation in the “brown lemur complex” (BLC) of Madagascar, which consists of seven allopatric populations of the genus Eulemur (Primates: Lemuridae), which were sampled extensively across northern, eastern and western Madagascar to collect fecal samples for DNA extraction as well as recordings of vocalizations. Our data base was extended by including museum specimens with reliable identification and locality information for skull shape and pelage color analysis. Results Between-group analyses of principal components revealed significant heterogeneity in skull shape, pelage color variation and loud calls across all seven populations. Furthermore, post-hoc statistical tests between pairs of populations revealed considerable discordance among different data sets for different dyads. Despite a high degree of incomplete lineage sorting among nuclear loci, significant exclusive ancestry was found for all populations, except for E. cinereiceps, based on one mitochondrial and three nuclear genetic loci. Conclusions Using several independent lines of evidence, our results confirm the species status of the members of the BLC under the general lineage concept of species. More generally, the present analyses demonstrate the importance and value of integrating different kinds of data in delimiting recently evolved radiations. PMID:24159931

  15. Effect of Oscillating Tabs on a Jet-in-Cross-Flow

    NASA Technical Reports Server (NTRS)

    Zaman, K. B. M. Q.

    2003-01-01

    A novel technique for active control of a jet-in-cross-flow is explored in this study. Two triangular tabs are placed at the 90 degree and 270 degree edges of the jet orifice, relative to the direction of the cross-flow. A slight asymmetry in the placement of the two tabs is reversed periodically. This causes a profound oscillation of the flow field that persists as far downstream as the measurements were permitted by the facility (100 orifice diameters). Parametric dependence of the unsteadiness and its impact on the flowfield has been investigated preliminarily. It is found that the effect becomes increasingly pronounced with increasing value of the momentum flux ratio (J). However, there is little or no effect at low values of J in the range, J less than 15. The effective frequencies of oscillation are low - more than an order of magnitude lower than that found with oscillatory blowing technique in previous studies. The flow mechanism apparently involves a direct perturbation of the counter-rotating streamwise vortex pair of the flow.

  16. Effect of delta tabs on mixing and axis switching in jets from asymmetric nozzles

    NASA Technical Reports Server (NTRS)

    Zaman, K. B. M. Q.

    1994-01-01

    The effect of delta tabs on mixing and the phenomenon of axis switching in free air jets from various asymmetric nozzles was studied experimentally. Flow visualization and Pitot probe surveys were carried out with a set of small nozzles (D = 1.47 cm) at a jet Mach number, Mj = 1.63. Hot wire measurements for streamwise vorticity were carried out with larger nozzles (D = 6.35 cm) at Mj = 0.31. Jet mixing with the asymmetric nozzles, as indicated by the mass fluxes downstream, was found to be higher than that produced by a circular nozzle. The circular nozzle with four delta tabs, however, produced fluxes much higher than that produced by a asymmetric nozzles themselves or by most of the tab configurations tried with them. Even higher fluxes could be obtained with only a few cases, e.g., with 3:1 rectangular nozzle with two large delta tabs placed on the narrow edges. In this case, the jet 'fanned out' at a large angle after going through one axis switch. The axis switching could be either stopped or augmented with suitable choice of the tab configurations. Two mechanisms are identified governing the phenomenon. One, as described in Ref. 12 and referred to here as the omega(sub Theta)-induced dynamics, is due to differential induced velocities of different segments of a rolled up azimuthal vortical structure. The other is the omega(sub x)-induced dynamics due to the induced velocities of streamwise vortex pairs in the flow. While the former dynamics are responsible for rapid axis switching in periodically forced jets, the effect of the tabs is governed mainly by the latter. It is inferred that both dynamics are active in a natural asymmetric jet issuing from a nozzle having an upstream contraction. The tendency for axis switching caused by the omega(sub Theta)-induced dynamics is resisted by the omega(sub x)-induced dynamics, leading to a delayed or no switch over in that case. In jets from orifices and in screeching jets, the omega(sub Theta)-induced dynamics

  17. TAB2 Is Essential for Prevention of Apoptosis in Fetal Liver but Not for Interleukin-1 Signaling

    PubMed Central

    Sanjo, Hideki; Takeda, Kiyoshi; Tsujimura, Tohru; Ninomiya-Tsuji, Jun; Matsumoto, Kunihiro; Akira, Shizuo

    2003-01-01

    The proinflammatory cytokine interleukin-1 (IL-1) transmits a signal via several critical cytoplasmic proteins such as MyD88, IRAKs and TRAF6. Recently, serine/threonine kinase TAK1 and TAK1 binding protein 1 and 2 (TAB1/2) have been identified as molecules involved in IL-1-induced TRAF6-mediated activation of AP-1 and NF-κB via mitogen-activated protein (MAP) kinases and IκB kinases, respectively. However, their physiological functions remain to be clarified. To elucidate their roles in vivo, we generated TAB2-deficient mice. The TAB2 deficiency was embryonic lethal due to liver degeneration and apoptosis. This phenotype was similar to that of NF-κB p65-, IKKβ-, and NEMO/IKKγ-deficient mice. However, the IL-1-induced activation of NF-κB and MAP kinases was not impaired in TAB2-deficient embryonic fibroblasts. These findings demonstrate that TAB2 is essential for embryonic development through prevention of liver apoptosis but not for the IL-1 receptor-mediated signaling pathway. PMID:12556483

  18. Tab2, a novel recombinant polypeptide tag offering sensitive and specific protein detection and reliable affinity purification.

    PubMed

    Crusius, Kerstin; Finster, Silke; McClary, John; Xia, Wei; Larsen, Brent; Schneider, Douglas; Lu, Hong-Tao; Biancalana, Sara; Xuan, Jian-Ai; Newton, Alicia; Allen, Debbie; Bringmann, Peter; Cobb, Ronald R

    2006-10-01

    The detection and purification of proteins are often time-consuming and frequently involve complicated protocols. The addition of a peptide tag to recombinant proteins can make this process more efficient. Many of the commonly used tags, such as Flagtrade mark, Myc, HA and V5 are recognized by specific monoclonal antibodies and therefore, allow immunoaffinity-based purification. Enhancing the current scope of flexibility in using diverse peptide tags, we report here the development of a novel, short polypeptide tag (Tab2) for detection and purification of recombinant proteins. The Tab2 epitope corresponds to the NH2-terminal seven amino acid residues of human TGFalpha. A monoclonal anti-Tab2 antibody was raised and characterized. To investigate the potential of this peptide sequence as a novel tag for recombinant proteins, we expressed several different recombinant proteins containing this tag in E. coli, baculovirus, and mammalian cells. The data presented demonstrates the Tab2 tag-anti-Tab2 antibody combination is a reliable tool enabling specific Western blot detection, FACS analysis, and immunoprecipitation as well as non-denaturing protein affinity purification.

  19. An ISA-TAB-Nano based data collection framework to support data-driven modelling of nanotoxicology.

    PubMed

    Marchese Robinson, Richard L; Cronin, Mark T D; Richarz, Andrea-Nicole; Rallo, Robert

    2015-01-01

    Analysis of trends in nanotoxicology data and the development of data driven models for nanotoxicity is facilitated by the reporting of data using a standardised electronic format. ISA-TAB-Nano has been proposed as such a format. However, in order to build useful datasets according to this format, a variety of issues has to be addressed. These issues include questions regarding exactly which (meta)data to report and how to report them. The current article discusses some of the challenges associated with the use of ISA-TAB-Nano and presents a set of resources designed to facilitate the manual creation of ISA-TAB-Nano datasets from the nanotoxicology literature. These resources were developed within the context of the NanoPUZZLES EU project and include data collection templates, corresponding business rules that extend the generic ISA-TAB-Nano specification as well as Python code to facilitate parsing and integration of these datasets within other nanoinformatics resources. The use of these resources is illustrated by a "Toy Dataset" presented in the Supporting Information. The strengths and weaknesses of the resources are discussed along with possible future developments.

  20. An ISA-TAB-Nano based data collection framework to support data-driven modelling of nanotoxicology

    PubMed Central

    Marchese Robinson, Richard L; Richarz, Andrea-Nicole; Rallo, Robert

    2015-01-01

    Summary Analysis of trends in nanotoxicology data and the development of data driven models for nanotoxicity is facilitated by the reporting of data using a standardised electronic format. ISA-TAB-Nano has been proposed as such a format. However, in order to build useful datasets according to this format, a variety of issues has to be addressed. These issues include questions regarding exactly which (meta)data to report and how to report them. The current article discusses some of the challenges associated with the use of ISA-TAB-Nano and presents a set of resources designed to facilitate the manual creation of ISA-TAB-Nano datasets from the nanotoxicology literature. These resources were developed within the context of the NanoPUZZLES EU project and include data collection templates, corresponding business rules that extend the generic ISA-TAB-Nano specification as well as Python code to facilitate parsing and integration of these datasets within other nanoinformatics resources. The use of these resources is illustrated by a “Toy Dataset” presented in the Supporting Information. The strengths and weaknesses of the resources are discussed along with possible future developments. PMID:26665069

  1. Construct User Guide

    DTIC Science & Technology

    2012-11-01

    interactions in construct: An empirical validation using calibrated grounding. In 2007 BRIMS Conference Proceedings, Norfolk, VA. Simon, H. A...by the path name. Users should ensure that if they have opened any output files (e.g., in Excel to view the files), they should either close the file...stringvars to delimit string variables. Common Gotchas If Construct is unable to open an input file, it will exit and close. There are times when an

  2. Integrating a Numerical Taxonomic Method and Molecular Phylogeny for Species Delimitation of Melampsora Species (Melampsoraceae, Pucciniales) on Willows in China

    PubMed Central

    Zhao, Peng; Wang, Qing-Hong; Tian, Cheng-Ming; Kakishima, Makoto

    2015-01-01

    The species in genus Melampsora are the causal agents of leaf rust diseases on willows in natural habitats and plantations. However, the classification and recognition of species diversity are challenging because morphological characteristics are scant and morphological variation in Melampsora on willows has not been thoroughly evaluated. Thus, the taxonomy of Melampsora species on willows remains confused, especially in China where 31 species were reported based on either European or Japanese taxonomic systems. To clarify the species boundaries of Melampsora species on willows in China, we tested two approaches for species delimitation inferred from morphological and molecular variations. Morphological species boundaries were determined based on numerical taxonomic analyses of morphological characteristics in the uredinial and telial stages by cluster analysis and one-way analysis of variance. Phylogenetic species boundaries were delineated based on the generalized mixed Yule-coalescent (GMYC) model analysis of the sequences of the internal transcribed spacer (ITS1 and ITS2) regions including the 5.8S and D1/D2 regions of the large nuclear subunit of the ribosomal RNA gene. Numerical taxonomic analyses of 14 morphological characteristics recognized in the uredinial-telial stages revealed 22 morphological species, whereas the GMYC results recovered 29 phylogenetic species. In total, 17 morphological species were in concordance with the phylogenetic species and 5 morphological species were in concordance with 12 phylogenetic species. Both the morphological and molecular data supported 14 morphological characteristics, including 5 newly recognized characteristics and 9 traditionally emphasized characteristics, as effective for the differentiation of Melampsora species on willows in China. Based on the concordance and discordance of the two species delimitation approaches, we concluded that integrative taxonomy by using both morphological and molecular variations was

  3. A recognizable systemic connective tissue disorder with polyvalvular heart dystrophy and dysmorphism associated with TAB2 mutations.

    PubMed

    Ritelli, M; Morlino, S; Giacopuzzi, E; Bernardini, L; Torres, B; Santoro, G; Ravasio, V; Chiarelli, N; D'Angelantonio, D; Novelli, A; Grammatico, P; Colombi, M; Castori, M

    2018-01-01

    Deletions encompassing TAK1-binding protein 2 (TAB2) associated with isolated and syndromic congenital heart defects. Rare missense variants are found in patients with a similar phenotype as well as in a single individual with frontometaphyseal dysplasia. We describe a family and an additional sporadic patient with polyvalvular heart disease, generalized joint hypermobility and related musculoskeletal complications, soft, velvety and hyperextensible skin, short limbs, hearing impairment, and facial dysmorphism. In the first family, whole-exome sequencing (WES) disclosed the novel TAB2 c.1398dup (p.Thr467Tyrfs*6) variant that eliminates the C-terminal zinc finger domain essential for activation of TAK1 (TGFβ-activated kinase 1)-dependent signaling pathways. The sporadic case carryed a ~2 Mb de novo deletion including 28 genes also comprising TAB2. This study reveal an association between TAB2 mutations and a phenotype resembling Ehlers-Danlos syndrome with severe polyvalvular heart disease and subtle facial dysmorphism. Our findings support the existence of a wider spectrum of clinical phenotypes associated with TAB2 perturbations and emphasize the role of TAK1 signaling network in human development. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  4. High-Throughput Tabular Data Processor - Platform independent graphical tool for processing large data sets.

    PubMed

    Madanecki, Piotr; Bałut, Magdalena; Buckley, Patrick G; Ochocka, J Renata; Bartoszewski, Rafał; Crossman, David K; Messiaen, Ludwine M; Piotrowski, Arkadiusz

    2018-01-01

    High-throughput technologies generate considerable amount of data which often requires bioinformatic expertise to analyze. Here we present High-Throughput Tabular Data Processor (HTDP), a platform independent Java program. HTDP works on any character-delimited column data (e.g. BED, GFF, GTF, PSL, WIG, VCF) from multiple text files and supports merging, filtering and converting of data that is produced in the course of high-throughput experiments. HTDP can also utilize itemized sets of conditions from external files for complex or repetitive filtering/merging tasks. The program is intended to aid global, real-time processing of large data sets using a graphical user interface (GUI). Therefore, no prior expertise in programming, regular expression, or command line usage is required of the user. Additionally, no a priori assumptions are imposed on the internal file composition. We demonstrate the flexibility and potential of HTDP in real-life research tasks including microarray and massively parallel sequencing, i.e. identification of disease predisposing variants in the next generation sequencing data as well as comprehensive concurrent analysis of microarray and sequencing results. We also show the utility of HTDP in technical tasks including data merge, reduction and filtering with external criteria files. HTDP was developed to address functionality that is missing or rudimentary in other GUI software for processing character-delimited column data from high-throughput technologies. Flexibility, in terms of input file handling, provides long term potential functionality in high-throughput analysis pipelines, as the program is not limited by the currently existing applications and data formats. HTDP is available as the Open Source software (https://github.com/pmadanecki/htdp).

  5. High-Throughput Tabular Data Processor – Platform independent graphical tool for processing large data sets

    PubMed Central

    Bałut, Magdalena; Buckley, Patrick G.; Ochocka, J. Renata; Bartoszewski, Rafał; Crossman, David K.; Messiaen, Ludwine M.; Piotrowski, Arkadiusz

    2018-01-01

    High-throughput technologies generate considerable amount of data which often requires bioinformatic expertise to analyze. Here we present High-Throughput Tabular Data Processor (HTDP), a platform independent Java program. HTDP works on any character-delimited column data (e.g. BED, GFF, GTF, PSL, WIG, VCF) from multiple text files and supports merging, filtering and converting of data that is produced in the course of high-throughput experiments. HTDP can also utilize itemized sets of conditions from external files for complex or repetitive filtering/merging tasks. The program is intended to aid global, real-time processing of large data sets using a graphical user interface (GUI). Therefore, no prior expertise in programming, regular expression, or command line usage is required of the user. Additionally, no a priori assumptions are imposed on the internal file composition. We demonstrate the flexibility and potential of HTDP in real-life research tasks including microarray and massively parallel sequencing, i.e. identification of disease predisposing variants in the next generation sequencing data as well as comprehensive concurrent analysis of microarray and sequencing results. We also show the utility of HTDP in technical tasks including data merge, reduction and filtering with external criteria files. HTDP was developed to address functionality that is missing or rudimentary in other GUI software for processing character-delimited column data from high-throughput technologies. Flexibility, in terms of input file handling, provides long term potential functionality in high-throughput analysis pipelines, as the program is not limited by the currently existing applications and data formats. HTDP is available as the Open Source software (https://github.com/pmadanecki/htdp). PMID:29432475

  6. Deadly Throwaways--Plastic Six-Pack Binders and Metal Pull-Tabs Doom Wildlife

    ERIC Educational Resources Information Center

    Ward, Penny

    1975-01-01

    Thousands of creatures are vulnerable to entrapment, entanglement, strangulation, or starvation as a result of plastic six-pack binders and metal pull-tabs. Possible solutions include: recycling, clean-up campaigns, and strong container legislation. (BT)

  7. Molecular phylogenetics and species delimitation of leaf-toed geckos (Phyllodactylidae: Phyllodactylus) throughout the Mexican tropical dry forest.

    PubMed

    Blair, Christopher; Méndez de la Cruz, Fausto R; Law, Christopher; Murphy, Robert W

    2015-03-01

    Methods and approaches for accurate species delimitation continue to be a highly controversial subject in the systematics community. Inaccurate assessment of species' limits precludes accurate inference of historical evolutionary processes. Recent evidence suggests that multilocus coalescent methods show promise in delimiting species in cryptic clades. We combine multilocus sequence data with coalescence-based phylogenetics in a hypothesis-testing framework to assess species limits and elucidate the timing of diversification in leaf-toed geckos (Phyllodactylus) of Mexico's dry forests. Tropical deciduous forests (TDF) of the Neotropics are among the planet's most diverse ecosystems. However, in comparison to moist tropical forests, little is known about the mode and tempo of biotic evolution throughout this threatened biome. We find increased speciation and substantial, cryptic molecular diversity originating following the formation of Mexican TDF 30-20million years ago due to orogenesis of the Sierra Madre Occidental and Mexican Volcanic Belt. Phylogenetic results suggest that the Mexican Volcanic Belt, the Rio Fuerte, and Isthmus of Tehuantepec may be important biogeographic barriers. Single- and multilocus coalescent analyses suggest that nearly every sampling locality may be a distinct species. These results suggest unprecedented levels of diversity, a complex evolutionary history, and that the formation and expansion of TDF vegetation in the Miocene may have influenced subsequent cladogenesis of leaf-toed geckos throughout western Mexico. Copyright © 2015 Elsevier Inc. All rights reserved.

  8. FunSimMat: a comprehensive functional similarity database

    PubMed Central

    Schlicker, Andreas; Albrecht, Mario

    2008-01-01

    Functional similarity based on Gene Ontology (GO) annotation is used in diverse applications like gene clustering, gene expression data analysis, protein interaction prediction and evaluation. However, there exists no comprehensive resource of functional similarity values although such a database would facilitate the use of functional similarity measures in different applications. Here, we describe FunSimMat (Functional Similarity Matrix, http://funsimmat.bioinf.mpi-inf.mpg.de/), a large new database that provides several different semantic similarity measures for GO terms. It offers various precomputed functional similarity values for proteins contained in UniProtKB and for protein families in Pfam and SMART. The web interface allows users to efficiently perform both semantic similarity searches with GO terms and functional similarity searches with proteins or protein families. All results can be downloaded in tab-delimited files for use with other tools. An additional XML–RPC interface gives automatic online access to FunSimMat for programs and remote services. PMID:17932054

  9. Lapin Data Interchange Among Database, Analysis and Display Programs Using XML-Based Text Files

    NASA Technical Reports Server (NTRS)

    2005-01-01

    The purpose of grant NCC3-966 was to investigate and evaluate the interchange of application-specific data among multiple programs each carrying out part of the analysis and design task. This has been carried out previously by creating a custom program to read data produced by one application and then write that data to a file whose format is specific to the second application that needs all or part of that data. In this investigation, data of interest is described using the XML markup language that allows the data to be stored in a text-string. Software to transform output data of a task into an XML-string and software to read an XML string and extract all or a portion of the data needed for another application is used to link two independent applications together as part of an overall design effort. This approach was initially used with a standard analysis program, Lapin, along with standard applications a standard spreadsheet program, a relational database program, and a conventional dialog and display program to demonstrate the successful sharing of data among independent programs. Most of the effort beyond that demonstration has been concentrated on the inclusion of more complex display programs. Specifically, a custom-written windowing program organized around dialogs to control the interactions have been combined with an independent CAD program (Open Cascade) that supports sophisticated display of CAD elements such as lines, spline curves, and surfaces and turbine-blade data produced by an independent blade design program (UD0300).

  10. Simultaneous delimitation of species and quantification of interspecific hybridization in Amazonian peacock cichlids (genus cichla) using multi-locus data

    PubMed Central

    2012-01-01

    Background Introgression likely plays a significant role in evolution, but understanding the extent and consequences of this process requires a clear identification of species boundaries in each focal group. The delimitation of species, however, is a contentious endeavor. This is true not only because of the inadequacy of current tools to identify species lineages, but also because of the inherent ambiguity between natural populations and species paradigms. The result has been a debate about the supremacy of various species concepts and criteria. Here, we utilized multiple separate sources of molecular data, mtDNA, nuclear sequences, and microsatellites, to delimit species under a polytypic species concept (PTSC) and estimate the frequency and genomic extent of introgression in a Neotropical genus of cichlid fishes (Cichla). We compared our inferences of species boundaries and introgression under this paradigm to those when species are identified under a diagnostic species concept (DSC). Results We find that, based on extensive molecular data and an inclusive species concept, 8 separate biological entities should be recognized rather than the 15 described species of Cichla. Under the PTSC, fewer individuals are expected to exhibit hybrid ancestry than under the DSC (~2% vs. ~12%), but a similar number of the species exhibit introgression from at least one other species (75% vs. 60%). Under either species concept, the phylogenetic breadth of introgression in this group is notable, with both sister species and species from different major mtDNA clades exhibiting introgression. Conclusions Introgression was observed to be a widespread phenomenon for delimited species in this group. While several instances of introgressive hybridization were observed in anthropogenically altered habitats, most were found in undisturbed natural habitats, suggesting that introgression is a natural but ephemeral part of the evolution of many tropical species. Nevertheless, even transient

  11. The Infant Version of the Laboratory Temperament Assessment Battery (Lab-TAB): Measurement Properties and Implications for Concepts of Temperament

    PubMed Central

    Planalp, Elizabeth M.; Van Hulle, Carol; Gagne, Jeffrey R.; Goldsmith, H. Hill

    2017-01-01

    We describe large-sample research using the Infant Laboratory Temperament Assessment Battery (Lab-TAB; Goldsmith and Rothbart, 1996) in 1,076 infants at 6 and 12 months of age. The Lab-TAB was designed to assess temperament dimensions through a series of episodes that mimic everyday situations. Our goal is to provide guidelines for scoring Lab-TAB episodes to derive temperament composites. We also present a set of analyses examining mean differences and stability of temperament in early infancy, gender differences in infant temperament, as well as a validation of Lab-TAB episodes and composites with parent reported Infant Behavior Questionnaire (IBQ; Rothbart, 1981) scales. In general, laboratory observed temperament was only modestly related to parent reported temperament. However, temperament measures were significantly stable across time and several gender differences that align with previous research emerged. In sum, the Lab-TAB usefully assesses individual differences in infant emotionality. PMID:28596748

  12. Shear flow control of cold and heated rectangular jets by mechanical tabs. Volume 1: Results and discussion

    NASA Technical Reports Server (NTRS)

    Brown, W. H.; Ahuja, K. K.

    1989-01-01

    The effects of mechanical protrusions on the jet mixing characteristics of rectangular nozzles for heated and unheated subsonic and supersonic jet plumes were studied. The characteristics of a rectangular nozzle of aspect ratio 4 without the mechanical protrusions were first investigated. Intrusive probes were used to make the flow measurements. Possible errors introduced by intrusive probes in making shear flow measurements were also examined. Several scaled sizes of mechanical tabs were then tested, configured around the perimeter of the rectangular jet. Both the number and the location of the tabs were varied. From this, the best configuration was selected. The conclusions derived were: (1) intrusive probes can produce significant errors in the measurements of the velocity of jets if they are large in diameter and penetrate beyond the jet center; (2) rectangular jets without tabs, compared to circular jets of the same exit area, provide faster jet mixing; and (3) further mixing enhancement is possible by using mechanical tabs.

  13. Shrimp TAB1 interacts with TAK1 and p38 and activates the host innate immune response to bacterial infection.

    PubMed

    Wang, Sheng; Li, Mengqiao; Yin, Bin; Li, Haoyang; Xiao, Bang; Lǚ, Kai; Huang, Zhijian; Li, Sedong; He, Jianguo; Li, Chaozheng

    2017-08-01

    Mammalian TAB1 has been previously identified as transforming growth factor-β (TGF-β)-activated kinase 1 (TAK1) binding protein, which functions as the activator of TAK1 and p38. This report, for the first time, identified and characterized the homolog of TAB1 in shrimp, to be specific, the homolog gene from Litopenaeus vannamei, containing a 1560-bp open reading frame (ORF) that encoded a putative protein of 519 amino acids with the conserved PP2Cc (Serine/threonine phosphatases, family 2C, catalytic) domain in N-terminal and a TAK1 binding motif in C-terminus, has been cloned and named LvTAB1. LvTAB1 was most abundant in gills and its expression could respond significantly to a series of stimuli, including LPS, Vibrio parahemolyticus and Staphylococcus aureus. Moreover, Co-immunoprecipitation (Co-IP) experiments showed that LvTAB1 could combine with LvTAK1 as well as Lvp38, two members of IMD-NF-κB/MAPK pathway, which meant LvTAB1 could have a role in regulating the activities of these kinases. Over-expression of LvTAB1 in drosophila S2 cells could improve the transcriptional levels of antimicrobial peptide genes (AMPs) such as Diptericin (Dpt), the hallmark of drosophila NF-κB activated genes, indicating its activation effect on NF-κB pathway. Furthermore, suppression of LvTAB1 expression in vivo by RNA-interference increased the sensibility of shrimps to V. parahaemolyticus infection, implying its protective role against bacterial infection. In conclusion, these results provide some insight into the function of LvTAB1 during bacterial infection. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. An evolutionarily conserved motif in the TAB1 C-terminal region is necessary for interaction with and activation of TAK1 MAPKKK.

    PubMed

    Ono, K; Ohtomo, T; Sato, S; Sugamata, Y; Suzuki, M; Hisamoto, N; Ninomiya-Tsuji, J; Tsuchiya, M; Matsumoto, K

    2001-06-29

    TAK1, a member of the MAPKKK family, is involved in the intracellular signaling pathways mediated by transforming growth factor beta, interleukin 1, and Wnt. TAK1 kinase activity is specifically activated by the TAK1-binding protein TAB1. The C-terminal 68-amino acid sequence of TAB1 (TAB1-C68) is sufficient for TAK1 interaction and activation. Analysis of various truncated versions of TAB1-C68 defined a C-terminal 30-amino acid sequence (TAB1-C30) necessary for TAK1 binding and activation. NMR studies revealed that the TAB1-C30 region has a unique alpha-helical structure. We identified a conserved sequence motif, PYVDXA/TXF, in the C-terminal domain of mammalian TAB1, Xenopus TAB1, and its Caenorhabditis elegans homolog TAP-1, suggesting that this motif constitutes a specific TAK1 docking site. Alanine substitution mutagenesis showed that TAB1 Phe-484, located in the conserved motif, is crucial for TAK1 binding and activation. The C. elegans homolog of TAB1, TAP-1, was able to interact with and activate the C. elegans homolog of TAK1, MOM-4. However, the site in TAP-1 corresponding to Phe-484 of TAB1 is an alanine residue (Ala-364), and changing this residue to Phe abrogates the ability of TAP-1 to interact with and activate MOM-4. These results suggest that the Phe or Ala residue within the conserved motif of the TAB1-related proteins is important for interaction with and activation of specific TAK1 MAPKKK family members in vivo.

  15. 18 CFR 34.7 - Number of copies to be filed.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., § 34.7 was revised, effective at the time of the next e-filing release during the Commission's next fiscal year. For the convenience of the user, the revised text follows: § 34.7 Filing requirements. Each...) and (2) of this chapter. As a qualified document, no paper copy version of the filing is required...

  16. Plate tectonics and offshore boundary delimitation: Tunisia-Libya case at the International Court of Justice

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stanley, D.J.

    1983-03-01

    Advances in the technology for exploiting resources of the oceans, particularly recovery of hydrocarbons and minerals in deep water, is benefiting a growing number of nations. At the same time, however, economic and political pressures have induced concern and there is now a much increased emphasis on jurisdiction to divide the offshore areas between the 132 coastal nations. Negotiations affect research operations at sea and, in consequence, marine scientists have been made aware of offshore problems as highlighted by the Law of the Sea Treaty (UNCLOS III) and complications arising from the legal versus scientific definitions of continental shelves andmore » margins. The first major offshore boundary case of international scope where plate tectonics has constituted a significant argument is the one recently brought before the International Court of Justice by Libya and Tunisia concerning the delimitation of their continental shelves. Of the two parties, Libya placed the greatest emphasis on this concept as a means to determine natural prolongation of its land territory into and under the sea. Tunisia contested Libya's use of the whole of the African continental landmass as a reference unit; in Tunisia's view, considerations of geography, geomorphology, and bathymetry are at least as relevant as are those of geology. In its landmark judgment (February 1982) - which almost certainly will have far-reaching consequences in future such boundary delimitation cases - the court pronounced that It is the outcome, not the evolution in the long-distant past, which is of importance, and that it is the present-day configuration of the coasts and sea bed which are the main factors to be considered, not geology.« less

  17. The Centipede Genus Scolopendra in Mainland Southeast Asia: Molecular Phylogenetics, Geometric Morphometrics and External Morphology as Tools for Species Delimitation

    PubMed Central

    Siriwut, Warut; Edgecombe, Gregory D.; Sutcharit, Chirasak; Panha, Somsak

    2015-01-01

    Seven Scolopendra species from the Southeast Asian mainland delimited based on standard external morphological characters represent monophyletic groups in phylogenetic trees inferred from concatenated sequences of three gene fragments (cytochrome c oxidase subunit 1, 16S rRNA and 28S rRNA) using Maximum likelihood and Bayesian inference. Geometric morphometric description of shape variation in the cephalic plate, forcipular coxosternite, and tergite of the ultimate leg-bearing segment provides additional criteria for distinguishing species. Colouration patterns in some Scolopendra species show a high degree of fit to phylogenetic trees at the population level. The most densely sampled species, Scolopendra dehaani Brandt, 1840, has three subclades with allopatric distributions in mainland SE Asia. The molecular phylogeny of S. pinguis Pocock, 1891, indicated ontogenetic colour variation among its populations. The taxonomic validation of S. dawydoffi Kronmüller, 2012, S. japonica Koch, 1878, and S. dehaani Brandt, 1840, each a former subspecies of S. subspinipes Leach, 1814 sensu Lewis, 2010, as full species was supported by molecular information and additional morphological data. Species delimitation in these taxonomically challenging animals is facilitated by an integrative approach that draws on both morphology and molecular phylogeny. PMID:26270342

  18. Observ-OM and Observ-TAB: Universal syntax solutions for the integration, search, and exchange of phenotype and genotype information.

    PubMed

    Adamusiak, Tomasz; Parkinson, Helen; Muilu, Juha; Roos, Erik; van der Velde, Kasper Joeri; Thorisson, Gudmundur A; Byrne, Myles; Pang, Chao; Gollapudi, Sirisha; Ferretti, Vincent; Hillege, Hans; Brookes, Anthony J; Swertz, Morris A

    2012-05-01

    Genetic and epidemiological research increasingly employs large collections of phenotypic and molecular observation data from high quality human and model organism samples. Standardization efforts have produced a few simple formats for exchange of these various data, but a lightweight and convenient data representation scheme for all data modalities does not exist, hindering successful data integration, such as assignment of mouse models to orphan diseases and phenotypic clustering for pathways. We report a unified system to integrate and compare observation data across experimental projects, disease databases, and clinical biobanks. The core object model (Observ-OM) comprises only four basic concepts to represent any kind of observation: Targets, Features, Protocols (and their Applications), and Values. An easy-to-use file format (Observ-TAB) employs Excel to represent individual and aggregate data in straightforward spreadsheets. The systems have been tested successfully on human biobank, genome-wide association studies, quantitative trait loci, model organism, and patient registry data using the MOLGENIS platform to quickly setup custom data portals. Our system will dramatically lower the barrier for future data sharing and facilitate integrated search across panels and species. All models, formats, documentation, and software are available for free and open source (LGPLv3) at http://www.observ-om.org. © 2012 Wiley Periodicals, Inc.

  19. Sequential neural text compression.

    PubMed

    Schmidhuber, J; Heil, S

    1996-01-01

    The purpose of this paper is to show that neural networks may be promising tools for data compression without loss of information. We combine predictive neural nets and statistical coding techniques to compress text files. We apply our methods to certain short newspaper articles and obtain compression ratios exceeding those of the widely used Lempel-Ziv algorithms (which build the basis of the UNIX functions "compress" and "gzip"). The main disadvantage of our methods is that they are about three orders of magnitude slower than standard methods.

  20. Lapin Data Interchange Among Database, Analysis and Display Programs Using XML-Based Text Files

    NASA Technical Reports Server (NTRS)

    2004-01-01

    The purpose was to investigate and evaluate the interchange of application- specific data among multiple programs each carrying out part of the analysis and design task. This has been carried out previously by creating a custom program to read data produced by one application and then write that data to a file whose format is specific to the second application that needs all or part of that data. In this investigation, data of interest is described using the XML markup language that allows the data to be stored in a text-string. Software to transform output data of a task into an XML-string and software to read an XML string and extract all or a portion of the data needed for another application is used to link two independent applications together as part of an overall design effort. This approach was initially used with a standard analysis program, Lapin, along with standard applications a standard spreadsheet program, a relational database program, and a conventional dialog and display program to demonstrate the successful sharing of data among independent programs. See Engineering Analysis Using a Web-Based Protocol by J.D. Schoeffler and R.W. Claus, NASA TM-2002-211981, October 2002. Most of the effort beyond that demonstration has been concentrated on the inclusion of more complex display programs. Specifically, a custom-written windowing program organized around dialogs to control the interactions have been combined with an independent CAD program (Open Cascade) that supports sophisticated display of CAD elements such as lines, spline curves, and surfaces and turbine-blade data produced by an independent blade design program (UD0300).

  1. Using Remote Sensing Technology on the Delimitation of the Conservation Area for the Jianan Irrigation System Cultural Landsccape

    NASA Astrophysics Data System (ADS)

    Wang, C. H.

    2015-08-01

    In recent years the cultural landscape has become an important issue for cultural heritages throughout the world. It represents the "combined works of nature and of man" designated in Article 1 of the World Heritage Convention. When a landscape has a cultural heritage value, important features should be marked and mapped through the delimitation of a conservation area, which may be essential for further conservation work. However, a cultural landscape's spatial area is usually wider than the ordinary architectural type of cultural heritage, since various elements and impact factors, forming the cultural landscape's character, lie within a wide geographic area. It is argued that the conservation of a cultural landscape may be influenced by the delimitation of the conservation area, the corresponding land management measures, the limits and encouragements. The Jianan Irrigation System, an historical cultural landscape in southern Taiwan, was registered as a living cultural heritage site in 2009. However, the system's conservation should not be limited to just only the reservoir or canals, but expanded to irrigated areas where farmland may be the most relevant. Through the analysis process, only approximately 42,000 hectares was defined as a conservation area, but closely related to agricultural plantations and irrigated by the system. This is only half of the 1977 irrigated area due to urban sprawl and continuous industrial expansion.

  2. Accessing files in an Internet: The Jade file system

    NASA Technical Reports Server (NTRS)

    Peterson, Larry L.; Rao, Herman C.

    1991-01-01

    Jade is a new distribution file system that provides a uniform way to name and access files in an internet environment. It makes two important contributions. First, Jade is a logical system that integrates a heterogeneous collection of existing file systems, where heterogeneous means that the underlying file systems support different file access protocols. Jade is designed under the restriction that the underlying file system may not be modified. Second, rather than providing a global name space, Jade permits each user to define a private name space. These private name spaces support two novel features: they allow multiple file systems to be mounted under one directory, and they allow one logical name space to mount other logical name spaces. A prototype of the Jade File System was implemented on Sun Workstations running Unix. It consists of interfaces to the Unix file system, the Sun Network File System, the Andrew File System, and FTP. This paper motivates Jade's design, highlights several aspects of its implementation, and illustrates applications that can take advantage of its features.

  3. Accessing files in an internet - The Jade file system

    NASA Technical Reports Server (NTRS)

    Rao, Herman C.; Peterson, Larry L.

    1993-01-01

    Jade is a new distribution file system that provides a uniform way to name and access files in an internet environment. It makes two important contributions. First, Jade is a logical system that integrates a heterogeneous collection of existing file systems, where heterogeneous means that the underlying file systems support different file access protocols. Jade is designed under the restriction that the underlying file system may not be modified. Second, rather than providing a global name space, Jade permits each user to define a private name space. These private name spaces support two novel features: they allow multiple file systems to be mounted under one directory, and they allow one logical name space to mount other logical name spaces. A prototype of the Jade File System was implemented on Sun Workstations running Unix. It consists of interfaces to the Unix file system, the Sun Network File System, the Andrew File System, and FTP. This paper motivates Jade's design, highlights several aspects of its implementation, and illustrates applications that can take advantage of its features.

  4. Preliminary Evidence for Feasibility, Use, and Acceptability of Individualized Texting for Adherence Building for Antiretroviral Adherence and Substance Use Assessment among HIV-Infected Methamphetamine Users

    PubMed Central

    Moore, David J.; Montoya, Jessica L.; Blackstone, Kaitlin; Depp, Colin A.; Atkinson, J. Hampton; TMARC Group, The

    2013-01-01

    The feasibility, use, and acceptability of text messages to track methamphetamine use and promote antiretroviral treatment (ART) adherence among HIV-infected methamphetamine users was examined. From an ongoing randomized controlled trial, 30-day text response rates of participants assigned to the intervention (individualized texting for adherence building (iTAB), n = 20) were compared to those in the active comparison condition (n = 9). Both groups received daily texts assessing methamphetamine use, and the iTAB group additionally received personalized daily ART adherence reminder texts. Response rate for methamphetamine use texts was 72.9% with methamphetamine use endorsed 14.7% of the time. Text-derived methamphetamine use data was correlated with data from a structured substance use interview covering the same time period (P < 0.05). The iTAB group responded to 69.0% of adherence reminder texts; among those responses, 81.8% endorsed taking ART medication. Standardized feedback questionnaire responses indicated little difficulty with the texts, satisfaction with the study, and beliefs that future text-based interventions would be helpful. Moreover, most participants believed the intervention reduced methamphetamine use and improved adherence. Qualitative feedback regarding the intervention was positive. Future studies will refine and improve iTAB for optimal acceptability and efficacy. This trial is registered with ClinicalTrials.gov NCT01317277. PMID:24078868

  5. Vortex dynamics in the near-wake of tabs with various geometries using 2D and 3D PIV

    NASA Astrophysics Data System (ADS)

    Pagan-Vazquez, Axy; Khovalyg, Dolaana; Marsh, Charles; Hamed, Ali M.; Chamorro, Leonardo P.

    2016-11-01

    The vortex dynamics and turbulence statistics in the near-wake of rectangular, trapezoidal, triangular, and ellipsoidal tabs were studied in a refractive-index-matching channel at Re = 2000 and 13000, based on the tab height. The tabs share the same bulk dimensions including a 17 mm height, a 28 mm base width, and a 24.5o angle. 3D PIV was used to study the mean flow and dominant large-scale vortices, while high-spatial resolution planar PIV was used to quantify high-order statistics. The results show the coexistence of counter-rotating vortex pair (CVP) and hairpin structures. These vortices exhibit distinctive topology and strength across Re and tab geometry. The CVP is a steady structure that grows in strength over a significantly longer distance at the low Re due to the lower turbulence levels and the delayed shedding of the hairpin vortices. These features at the low Re are associated with the presence of K-H instability that develops over three tab heights. The interaction between the hairpins and CVP is measured in 3D for the first time and shows complex coexistence. Although the CVP suffers deformation and splitting at times, it maintains its presence and leads to significant spanwise and wall-normal flows.

  6. Use of electromagnetic induction surveys to delimit zones of contrasting tree development in an irrigated olive orchard in Southern Spain.

    NASA Astrophysics Data System (ADS)

    Pedrera, Aura; Vanderlinden, Karl; Jesús Espejo-Pérez, Antonio; Gómez, José Alfonso; Giráldez, Juan Vicente

    2014-05-01

    Olives are historically closely linked to Mediterranean culture and have nowadays important societal and economical implications. Improving yield and preventing infestation by soil-borne pathogens are crucial issues in maintaining olive cropping competitive. In order to assess both issues properly at the farm or field scale, accurate knowledge of the spatial distribution of soil physical properties and associated water dynamics is required. Conventional soil surveying is generally prohibitive at commercial farms, but electromagnetic induction (EMI) sensors, measuring soil apparent electrical conductivity (ECa) provide a suitable alternative. ECa depends strongly on soil texture and water content and has been used exhaustively in precision agriculture to delimit management zones. The aim of this study was to delimit areas with unsatisfactory tree development in an olive orchard using EMI, and to identify the underlying relationships between ECa and the soil properties driving the spatial tree development pattern. An experimental catchment in S. Spain dedicated to irrigated olive cropping was surveyed for ECa under dry and wet soil conditions (0.06 vs. 0.22 g/g, respectively), using a Dualem 21-S EMI sensor. In addition, ECa and gravimetric soil water content (SWC) was measured at 45 locations throughout the catchment during each survey. At each of these locations, soil profile samples were collected to determine textural class including coarse particles content, organic matter (OM), and bulk density. Measurements for dry soil conditions with the perpendicular coil configuration with a separation of 2.1 m (P2.1) were chosen to make a first assessment of the orchard-growth variability. According to the shape of the histogram, the P2.1 ECa values were classified to delimit three areas in the field for which canopy coverage was estimated. Combining the 4 ECa signals for the wet and dry surveys, a principal component (PC) analysis showed that 91% of the total variance

  7. Text and Illustration Processing System (TIPS) User’s Manual. Volume 1. Text Processing System.

    DTIC Science & Technology

    1981-07-01

    m.st De in tre file citalog. To copy a file, begin by calling up the file. Access the Main Menu and, T<ESSq: 2 - Edit an Existing File After you have...23 III MAKING REVISIONS............................................ 24 Call Up an Existing File...above the keyboard is called a Cathode Ray Tube (CRT). It displays information as you key it in. A CURSOR is an underscore character on the screen which

  8. Lineage diversification of fringe-toed lizards (Phrynosomatidae: Uma notata complex) in the Colorado Desert: Delimiting species in the presence of gene flow

    USGS Publications Warehouse

    Gottscho, Andrew D.; Wood, Dustin A.; Vandergast, Amy; Lemos Espinal, Julio A.; Gatesy, John; Reeder, Tod

    2017-01-01

    Multi-locus nuclear DNA data were used to delimit species of fringe-toed lizards of theUma notata complex, which are specialized for living in wind-blown sand habitats in the deserts of southwestern North America, and to infer whether Quaternary glacial cycles or Tertiary geological events were important in shaping the historical biogeography of this group. We analyzed ten nuclear loci collected using Sanger sequencing and genome-wide sequence and single-nucleotide polymorphism (SNP) data collected using restriction-associated DNA (RAD) sequencing. A combination of species discovery methods (concatenated phylogenies, parametric and non-parametric clustering algorithms) and species validation approaches (coalescent-based species tree/isolation-with-migration models) were used to delimit species, infer phylogenetic relationships, and to estimate effective population sizes, migration rates, and speciation times. Uma notata, U. inornata, U. cowlesi, and an undescribed species from Mohawk Dunes, Arizona (U. sp.) were supported as distinct in the concatenated analyses and by clustering algorithms, and all operational taxonomic units were decisively supported as distinct species by ranking hierarchical nested speciation models with Bayes factors based on coalescent-based species tree methods. However, significant unidirectional gene flow (2NM >1) from U. cowlesi and U. notata into U. rufopunctata was detected under the isolation-with-migration model. Therefore, we conservatively delimit four species-level lineages within this complex (U. inornata, U. notata, U. cowlesi, and U. sp.), treating U. rufopunctata as a hybrid population (U. notata x cowlesi). Both concatenated and coalescent-based estimates of speciation times support the hypotheses that speciation within the complex occurred during the late Pleistocene, and that the geological evolution of the Colorado River delta during this period was an important process shaping the observed phylogeographic patterns.

  9. A Detailed Examination of the GPM Core Satellite Gridded Text Product

    NASA Technical Reports Server (NTRS)

    Stocker, Erich Franz; Kelley, Owen A.; Kummerow, C.; Huffman, George; Olson, William S.; Kwiatowski, John M.

    2015-01-01

    The Global Precipitation Measurement (GPM) mission quarter-degree gridded-text product has a similar file format and a similar purpose as the Tropical Rainfall Measuring Mission (TRMM) 3G68 quarter-degree product. The GPM text-grid format is an hourly summary of surface precipitation retrievals from various GPM instruments and combinations of GPM instruments. The GMI Goddard Profiling (GPROF) retrieval provides the widest swath (800 km) and does the retrieval using the GPM Microwave Imager (GMI). The Ku radar provides the widest radar swath (250 km swath) and also provides continuity with the TRMM Ku Precipitation Radar. GPM's Ku+Ka band matched swath (125 km swath) provides a dual-frequency precipitation retrieval. The "combined" retrieval (125 km swath) provides a multi-instrument precipitation retrieval based on the GMI, the DPR Ku radar, and the DPR Ka radar. While the data are reported in hourly grids, all hours for a day are packaged into a single text file that is g-zipped to reduce file size and to speed up downloading. The data are reported on a 0.25deg x 0.25 deg grid.

  10. OryzaGenome: Genome Diversity Database of Wild Oryza Species.

    PubMed

    Ohyanagi, Hajime; Ebata, Toshinobu; Huang, Xuehui; Gong, Hao; Fujita, Masahiro; Mochizuki, Takako; Toyoda, Atsushi; Fujiyama, Asao; Kaminuma, Eli; Nakamura, Yasukazu; Feng, Qi; Wang, Zi-Xuan; Han, Bin; Kurata, Nori

    2016-01-01

    The species in the genus Oryza, encompassing nine genome types and 23 species, are a rich genetic resource and may have applications in deeper genomic analyses aiming to understand the evolution of plant genomes. With the advancement of next-generation sequencing (NGS) technology, a flood of Oryza species reference genomes and genomic variation information has become available in recent years. This genomic information, combined with the comprehensive phenotypic information that we are accumulating in our Oryzabase, can serve as an excellent genotype-phenotype association resource for analyzing rice functional and structural evolution, and the associated diversity of the Oryza genus. Here we integrate our previous and future phenotypic/habitat information and newly determined genotype information into a united repository, named OryzaGenome, providing the variant information with hyperlinks to Oryzabase. The current version of OryzaGenome includes genotype information of 446 O. rufipogon accessions derived by imputation and of 17 accessions derived by imputation-free deep sequencing. Two variant viewers are implemented: SNP Viewer as a conventional genome browser interface and Variant Table as a text-based browser for precise inspection of each variant one by one. Portable VCF (variant call format) file or tab-delimited file download is also available. Following these SNP (single nucleotide polymorphism) data, reference pseudomolecules/scaffolds/contigs and genome-wide variation information for almost all of the closely and distantly related wild Oryza species from the NIG Wild Rice Collection will be available in future releases. All of the resources can be accessed through http://viewer.shigen.info/oryzagenome/. © The Author 2015. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists.

  11. P2P Watch: Personal Health Information Detection in Peer-to-Peer File-Sharing Networks

    PubMed Central

    El Emam, Khaled; Arbuckle, Luk; Neri, Emilio; Rose, Sean; Jonker, Elizabeth

    2012-01-01

    Background Users of peer-to-peer (P2P) file-sharing networks risk the inadvertent disclosure of personal health information (PHI). In addition to potentially causing harm to the affected individuals, this can heighten the risk of data breaches for health information custodians. Automated PHI detection tools that crawl the P2P networks can identify PHI and alert custodians. While there has been previous work on the detection of personal information in electronic health records, there has been a dearth of research on the automated detection of PHI in heterogeneous user files. Objective To build a system that accurately detects PHI in files sent through P2P file-sharing networks. The system, which we call P2P Watch, uses a pipeline of text processing techniques to automatically detect PHI in files exchanged through P2P networks. P2P Watch processes unstructured texts regardless of the file format, document type, and content. Methods We developed P2P Watch to extract and analyze PHI in text files exchanged on P2P networks. We labeled texts as PHI if they contained identifiable information about a person (eg, name and date of birth) and specifics of the person’s health (eg, diagnosis, prescriptions, and medical procedures). We evaluated the system’s performance through its efficiency and effectiveness on 3924 files gathered from three P2P networks. Results P2P Watch successfully processed 3924 P2P files of unknown content. A manual examination of 1578 randomly selected files marked by the system as non-PHI confirmed that these files indeed did not contain PHI, making the false-negative detection rate equal to zero. Of 57 files marked by the system as PHI, all contained both personally identifiable information and health information: 11 files were PHI disclosures, and 46 files contained organizational materials such as unfilled insurance forms, job applications by medical professionals, and essays. Conclusions PHI can be successfully detected in free-form textual

  12. P2P watch: personal health information detection in peer-to-peer file-sharing networks.

    PubMed

    Sokolova, Marina; El Emam, Khaled; Arbuckle, Luk; Neri, Emilio; Rose, Sean; Jonker, Elizabeth

    2012-07-09

    Users of peer-to-peer (P2P) file-sharing networks risk the inadvertent disclosure of personal health information (PHI). In addition to potentially causing harm to the affected individuals, this can heighten the risk of data breaches for health information custodians. Automated PHI detection tools that crawl the P2P networks can identify PHI and alert custodians. While there has been previous work on the detection of personal information in electronic health records, there has been a dearth of research on the automated detection of PHI in heterogeneous user files. To build a system that accurately detects PHI in files sent through P2P file-sharing networks. The system, which we call P2P Watch, uses a pipeline of text processing techniques to automatically detect PHI in files exchanged through P2P networks. P2P Watch processes unstructured texts regardless of the file format, document type, and content. We developed P2P Watch to extract and analyze PHI in text files exchanged on P2P networks. We labeled texts as PHI if they contained identifiable information about a person (eg, name and date of birth) and specifics of the person's health (eg, diagnosis, prescriptions, and medical procedures). We evaluated the system's performance through its efficiency and effectiveness on 3924 files gathered from three P2P networks. P2P Watch successfully processed 3924 P2P files of unknown content. A manual examination of 1578 randomly selected files marked by the system as non-PHI confirmed that these files indeed did not contain PHI, making the false-negative detection rate equal to zero. Of 57 files marked by the system as PHI, all contained both personally identifiable information and health information: 11 files were PHI disclosures, and 46 files contained organizational materials such as unfilled insurance forms, job applications by medical professionals, and essays. PHI can be successfully detected in free-form textual files exchanged through P2P networks. Once the files

  13. A Novel Wheat C-bZIP Gene, TabZIP14-B, Participates in Salt and Freezing Tolerance in Transgenic Plants

    PubMed Central

    Zhang, Lina; Zhang, Lichao; Xia, Chuan; Gao, Lifeng; Hao, Chenyang; Zhao, Guangyao; Jia, Jizeng; Kong, Xiuying

    2017-01-01

    The group C-bZIP transcription factors (TFs) are involved in diverse biological processes, such as the regulation of seed storage protein (SSP) production and the responses to pathogen challenge and abiotic stress. However, our knowledge of the abiotic functions of group C-bZIP genes in wheat remains limited. Here, we present the function of a novel TabZIP14-B gene in wheat. This gene belongs to the group C-bZIP TFs and contains six exons and five introns; three haplotypes were identified among accessions of tetraploid and hexaploid wheat. A subcellular localization analysis indicated that TabZIP14-B was targeted to the nucleus of tobacco epidermal cells. A transactivation assay demonstrated that TabZIP14-B showed transcriptional activation ability and was capable of binding the abscisic acid (ABA) responsive element (ABRE) in yeast. RT-qPCR revealed that TabZIP14-B was expressed in the roots, stems, leaves, and young spikes and was up-regulated by exogenous ABA, salt, low-temperature, and polyethylene glycol (PEG) stress treatments. Furthermore, Arabidopsis plants overexpressing TabZIP14-B exhibited enhanced tolerance to salt, freezing stresses and ABA sensitivity. Overexpression of TabZIP14-B resulted in increased expression of the AtRD29A, AtCOR47, AtRD20, AtGSTF6, and AtRAB18 genes and changes in several physiological characteristics. These results suggest that TabZIP14-B could function as a positive regulator in mediating the abiotic stress response. PMID:28536588

  14. Comparison of four species-delimitation methods applied to a DNA barcode data set of insect larvae for use in routine bioassessment for use in routine bioassessment

    EPA Science Inventory

    Species delimitation (grouping individuals into distinct taxonomic groups) is an essential part of evolutionary, conservation, and molecular ecology. Deoxyribonucleic acid (DNA) barcodes, short fragments of the cytochrome c oxidase subunit I (COI) gene, are being used in environm...

  15. Delimiting Species-Poor Data Sets using Single Molecular Markers: A Study of Barcode Gaps, Haplowebs and GMYC.

    PubMed

    Dellicour, Simon; Flot, Jean-François

    2015-11-01

    Most single-locus molecular approaches to species delimitation available to date have been designed and tested on data sets comprising at least tens of species, whereas the opposite case (species-poor data sets for which the hypothesis that all individuals are conspecific cannot by rejected beforehand) has rarely been the focus of such attempts. Here we compare the performance of barcode gap detection, haplowebs and generalized mixed Yule-coalescent (GMYC) models to delineate chimpanzees and bonobos using nuclear sequence markers, then apply these single-locus species delimitation methods to data sets of one, three, or six species simulated under a wide range of population sizes, speciation rates, mutation rates and sampling efforts. Our results show that barcode gap detection and GMYC models are unable to delineate species properly in data sets composed of one or two species, two situations in which haplowebs outperform them. For data sets composed of three or six species, bGMYC and haplowebs outperform the single-threshold and multiple-threshold versions of GMYC, whereas a clear barcode gap is only observed when population sizes and speciation rates are both small. The latter conditions represent a "sweet spot" for molecular taxonomy where all the single-locus approaches tested work well; however, the performance of these methods decreases strongly when population sizes and speciation rates are high, suggesting that multilocus approaches may be necessary to tackle such cases. © The Author(s) 2015. Published by Oxford University Press, on behalf of the Society of Systematic Biologists. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  16. Integrative Taxonomy and Species Delimitation in Harvestmen: A Revision of the Western North American Genus Sclerobunus (Opiliones: Laniatores: Travunioidea)

    PubMed Central

    Derkarabetian, Shahan; Hedin, Marshal

    2014-01-01

    Alpha taxonomy, and specifically the delimitation of species, is becoming increasingly objective and integrative. The use of coalescent-based methods applied to genetic data is providing new tools for the discovery and delimitation of species. Here, we use an integrative approach via a combination of discovery-based multivariate morphological analyses to detect potential new species. These potential species are then used as a priori species in hypothesis-driven validation analyses with genetic data. This research focuses on the harvestmen genus Sclerobunus found throughout the mountainous regions of western North America. Based on our analyses, we conduct a revision of Sclerobunus resulting in synonymy of Cyptobunus with Sclerobunus including transfer of S. cavicolens comb. nov. and elevation of both subspecies of S. ungulatus: S. ungulatus comb. nov. and S. madhousensis comb. nov., stat. nov. The three subspecies of S. robustus are elevated, S. robustus, S. glorietus stat. nov., and S. idahoensis stat. nov. Additionally, five new species of Sclerobunus are described from New Mexico and Colorado, including S. jemez sp. nov., S. klomax sp. nov., S. skywalkeri sp. nov., S. speoventus sp. nov., and S. steinmanni sp. nov. Several of the newly described species are single-cave endemics, and our findings suggest that further exploration of western North American cave habitats will likely yield additional new species. PMID:25144370

  17. Parametric and non-parametric species delimitation methods result in the recognition of two new Neotropical woody bamboo species.

    PubMed

    Ruiz-Sanchez, Eduardo

    2015-12-01

    The Neotropical woody bamboo genus Otatea is one of five genera in the subtribe Guaduinae. Of the eight described Otatea species, seven are endemic to Mexico and one is also distributed in Central and South America. Otatea acuminata has the widest geographical distribution of the eight species, and two of its recently collected populations do not match the known species morphologically. Parametric and non-parametric methods were used to delimit the species in Otatea using five chloroplast markers, one nuclear marker, and morphological characters. The parametric coalescent method and the non-parametric analysis supported the recognition of two distinct evolutionary lineages. Molecular clock estimates were used to estimate divergence times in Otatea. The results for divergence time in Otatea estimated the origin of the speciation events from the Late Miocene to Late Pleistocene. The species delimitation analyses (parametric and non-parametric) identified that the two populations of O. acuminata from Chiapas and Hidalgo are from two separate evolutionary lineages and these new species have morphological characters that separate them from O. acuminata s.s. The geological activity of the Trans-Mexican Volcanic Belt and the Isthmus of Tehuantepec may have isolated populations and limited the gene flow between Otatea species, driving speciation. Based on the results found here, I describe Otatea rzedowskiorum and Otatea victoriae as two new species, morphologically different from O. acuminata. Copyright © 2015 Elsevier Inc. All rights reserved.

  18. The BioGRID interaction database: 2013 update.

    PubMed

    Chatr-Aryamontri, Andrew; Breitkreutz, Bobby-Joe; Heinicke, Sven; Boucher, Lorrie; Winter, Andrew; Stark, Chris; Nixon, Julie; Ramage, Lindsay; Kolas, Nadine; O'Donnell, Lara; Reguly, Teresa; Breitkreutz, Ashton; Sellam, Adnane; Chen, Daici; Chang, Christie; Rust, Jennifer; Livstone, Michael; Oughtred, Rose; Dolinski, Kara; Tyers, Mike

    2013-01-01

    The Biological General Repository for Interaction Datasets (BioGRID: http//thebiogrid.org) is an open access archive of genetic and protein interactions that are curated from the primary biomedical literature for all major model organism species. As of September 2012, BioGRID houses more than 500 000 manually annotated interactions from more than 30 model organisms. BioGRID maintains complete curation coverage of the literature for the budding yeast Saccharomyces cerevisiae, the fission yeast Schizosaccharomyces pombe and the model plant Arabidopsis thaliana. A number of themed curation projects in areas of biomedical importance are also supported. BioGRID has established collaborations and/or shares data records for the annotation of interactions and phenotypes with most major model organism databases, including Saccharomyces Genome Database, PomBase, WormBase, FlyBase and The Arabidopsis Information Resource. BioGRID also actively engages with the text-mining community to benchmark and deploy automated tools to expedite curation workflows. BioGRID data are freely accessible through both a user-defined interactive interface and in batch downloads in a wide variety of formats, including PSI-MI2.5 and tab-delimited files. BioGRID records can also be interrogated and analyzed with a series of new bioinformatics tools, which include a post-translational modification viewer, a graphical viewer, a REST service and a Cytoscape plugin.

  19. Polarization radiation in the planetary atmosphere delimited by a heterogeneous diffusely reflecting surface

    NASA Technical Reports Server (NTRS)

    Strelkov, S. A.; Sushkevich, T. A.

    1983-01-01

    Spatial frequency characteristics (SFC) and the scattering functions were studied in the two cases of a uniform horizontal layer with absolutely black bottom, and an isolated layer. The mathematical model for these examples describes the horizontal heterogeneities in a light field with regard to radiation polarization in a three dimensional planar atmosphere, delimited by a heterogeneous surface with diffuse reflection. The perturbation method was used to obtain vector transfer equations which correspond to the linear and nonlinear systems of polarization radiation transfer. The boundary value tasks for the vector transfer equation that is a parametric set and one dimensional are satisfied by the SFC of the nonlinear system, and are expressed through the SFC of linear approximation. As a consequence of the developed theory, formulas were obtained for analytical calculation of albedo in solving the task of dissemination of polarization radiation in the planetary atmosphere with uniform Lambert bottom.

  20. 77 FR 5067 - Self-Regulatory Organizations; National Stock Exchange, Inc.; Notice of Filing and Immediate...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-01

    ... instant rule filing, the Exchange is proposing to amend the text of the Certificate previously filed with... rule change that are filed with the Commission, and all written communications relating to the proposed...

  1. SIM_ADJUST -- A computer code that adjusts simulated equivalents for observations or predictions

    USGS Publications Warehouse

    Poeter, Eileen P.; Hill, Mary C.

    2008-01-01

    This report documents the SIM_ADJUST computer code. SIM_ADJUST surmounts an obstacle that is sometimes encountered when using universal model analysis computer codes such as UCODE_2005 (Poeter and others, 2005), PEST (Doherty, 2004), and OSTRICH (Matott, 2005; Fredrick and others (2007). These codes often read simulated equivalents from a list in a file produced by a process model such as MODFLOW that represents a system of interest. At times values needed by the universal code are missing or assigned default values because the process model could not produce a useful solution. SIM_ADJUST can be used to (1) read a file that lists expected observation or prediction names and possible alternatives for the simulated values; (2) read a file produced by a process model that contains space or tab delimited columns, including a column of simulated values and a column of related observation or prediction names; (3) identify observations or predictions that have been omitted or assigned a default value by the process model; and (4) produce an adjusted file that contains a column of simulated values and a column of associated observation or prediction names. The user may provide alternatives that are constant values or that are alternative simulated values. The user may also provide a sequence of alternatives. For example, the heads from a series of cells may be specified to ensure that a meaningful value is available to compare with an observation located in a cell that may become dry. SIM_ADJUST is constructed using modules from the JUPITER API, and is intended for use on any computer operating system. SIM_ADJUST consists of algorithms programmed in Fortran90, which efficiently performs numerical calculations.

  2. 29 CFR 4007.3 - Filing requirement; method of filing.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Filing requirement; method of filing. 4007.3 Section 4007.3... PREMIUMS § 4007.3 Filing requirement; method of filing. (a) In general. The estimation, determination... Web site (http://www.pbgc.gov). Subject to the provisions of § 4007.13, the plan administrator of each...

  3. Society Influencing Science: The role of the Transdisciplinary Advisory Board (TAB) of the European Joint Programming Initiative on Climate.

    NASA Astrophysics Data System (ADS)

    Noone, K. J.; Manderscheid, P.; Monfray, P.

    2017-12-01

    It is becoming increasingly apparent that the separation between science and the rest of society is not helping us find solutions to "wicked" problems like climate change or achieving the Sustainable Development Goals. It is clear that a broader approach to research is necessary - one that includes stakeholders in the research process itself. What is unclear is how best to do this. The Transdisciplinary Advisory Board (TAB) of the European Joint Programming Initiative on Climate (JPI Climate) is an example of scientists and stakeholders working together to frame climate research and move the results of scientific research into decision support. JPI Climate is a consortium of 12 European countries (with partners from nine more countries) and is a major funding channel and forum for climate research in Europe. The TAB has an equal number of stakeholders and researchers from 10 different European countries, has an even gender balance, and its members have widely differing backgrounds. The TAB provides input and advice to the governing board of JPI Climate, and influences both the strategic planning for this funding initiative as well as specific calls for proposals issued through the consortium. In addition to its advisory role, the TAB explores the transdisciplinary process itself, expanding the boundaries of how stakeholders and science can interact positively. The TAB is a two-way mechanism through which stakeholders can help improve research and science can help improve society. We will give examples of the spectrum of how the TAB provides mutual influence between stakeholders and science - from helping to draft 10-year research strategies to helping advance the uptake of climate research into the private and policy sectors.

  4. Text-interpreter language for flexible generation of patient notes and instructions.

    PubMed

    Forker, T S

    1992-01-01

    An interpreted computer language has been developed along with a windowed user interface and multi-printer-support formatter to allow preparation of documentation of patient visits, including progress notes, prescriptions, excuses for work/school, outpatient laboratory requisitions, and patient instructions. Input is by trackball or mouse with little or no keyboard skill required. For clinical problems with specific protocols, the clinician can be prompted with problem-specific items of history, exam, and lab data to be gathered and documented. The language implements a number of text-related commands as well as branching logic and arithmetic commands. In addition to generating text, it is simple to implement arithmetic calculations such as weight-specific drug dosages; multiple branching decision-support protocols for paramedical personnel (or physicians); and calculation of clinical scores (e.g., coma or trauma scores) while simultaneously documenting the status of each component of the score. ASCII text files produced by the interpreter are available for computerized quality audit. Interpreter instructions are contained in text files users can customize with any text editor.

  5. DSSTOX MASTER STRUCTURE-INDEX FILE: SDF FILE AND ...

    EPA Pesticide Factsheets

    The DSSTox Master Structure-Index File serves to consolidate, manage, and ensure quality and uniformity of the chemical and substance information spanning all DSSTox Structure Data Files, including those in development but not yet published separately on this website. The DSSTox Master Structure-Index File serves to consolidate, manage, and ensure quality and uniformity of the chemical and substance information spanning all DSSTox Structure Data Files, including those in development but not yet published separately on this website.

  6. Please Move Inactive Files Off the /projects File System | High-Performance

    Science.gov Websites

    Computing | NREL Please Move Inactive Files Off the /projects File System Please Move Inactive Files Off the /projects File System January 11, 2018 The /projects file system is a shared resource . This year this has created a space crunch - the file system is now about 90% full and we need your help

  7. Cophylogeny of the anther smut fungi and their caryophyllaceous hosts: Prevalence of host shifts and importance of delimiting parasite species for inferring cospeciation

    PubMed Central

    2008-01-01

    Background Using phylogenetic approaches, the expectation that parallel cladogenesis should occur between parasites and hosts has been validated in some studies, but most others provided evidence for frequent host shifts. Here we examine the evolutionary history of the association between Microbotryum fungi that cause anther smut disease and their Caryophyllaceous hosts. We investigated the congruence between host and parasite phylogenies, inferred cospeciation events and host shifts, and assessed whether geography or plant ecology could have facilitated the putative host shifts identified. For cophylogeny analyses on microorganisms, parasite strains isolated from different host species are generally considered to represent independent evolutionary lineages, often without checking whether some strains actually belong to the same generalist species. Such an approach may mistake intraspecific nodes for speciation events and thus bias the results of cophylogeny analyses if generalist species are found on closely related hosts. A second aim of this study was therefore to evaluate the impact of species delimitation on the inferences of cospeciation. Results We inferred a multiple gene phylogeny of anther smut strains from 21 host plants from several geographic origins, complementing a previous study on the delimitation of fungal species and their host specificities. We also inferred a multi-gene phylogeny of their host plants, and the two phylogenies were compared. A significant level of cospeciation was found when each host species was considered to harbour a specific parasite strain, i.e. when generalist parasite species were not recognized as such. This approach overestimated the frequency of cocladogenesis because individual parasite species capable of infecting multiple host species (i.e. generalists) were found on closely related hosts. When generalist parasite species were appropriately delimited and only a single representative of each species was retained

  8. 77 FR 74116 - Extension of Tolerances for Emergency Exemptions (Multiple Chemicals)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-13

    .../text/text-idx?&c=ecfr&tpl=/ecfrbrowse/Title40/40tab_02.tpl . C. How can I file an objection or hearing... Management and Budget (OMB) has exempted these types of actions from review under Executive Order 12866.... 601 et seq.), do not apply. This final rule directly regulates growers, food processors, food handlers...

  9. Application of LANDSAT data to delimitation of avalanche hazards in Montane Colorado

    NASA Technical Reports Server (NTRS)

    Knepper, D. H., Jr. (Principal Investigator)

    1977-01-01

    The author has identified the following significant results. Many avalanche hazard zones can be identified on LANDSAT imagery, but not consistently over a large region. Therefore, regional avalanche hazard mapping, using LANDSAT imagery, must draw on additional sources of information. A method was devised that depicts three levels of avalanche hazards according to three corresponding levels of certainty that active avalanches occur. The lowest level, potential avalanche hazards, was defined by delineating slopes steep enough to support avalanches at elevations where snowfall was likely to be sufficient to produce a thick snowpack. The intermediate level of avalanche hazard was interpreted as avalanche hazard zones. These zones have direct and indirect indicators of active avalanche activity and were interpreted from LANDSAT imagery. The highest level of known or active avalanche hazards was compiled from existing maps. Some landslides in Colorado were identified and, to a degree, delimited on LANDSAT imagery, but the conditions of their identification were highly variable. Because of local topographic, geologic, structural, and vegetational variations, there was no unique landslide spectral appearance.

  10. Species delimitation in Trametes: a comparison of ITS, RPB1, RPB2 and TEF1 gene phylogenies.

    PubMed

    Carlson, Alexis; Justo, Alfredo; Hibbett, David S

    2014-01-01

    Trametes is a cosmopolitan genus of white rot polypores, including the "turkey tail" fungus, T. versicolor. Although Trametes is one of the most familiar genera of polypores, its species-level taxonomy is unsettled. The ITS region is the most commonly used molecular marker for species delimitation in fungi, but it has been shown to have a low molecular variation in Trametes resulting in poorly resolved phylogenies and unclear species boundaries, especially in the T. versicolor species complex (T. versicolor sensu stricto, T. ochracea, T. pubescens, T. ectypa). Here we evaluate the performance of three protein-coding genes (TEF1, RPB1, RPB2) for species delimitation and phylogenetic reconstruction in Trametes. We obtained 59 TEF1, 34 RPB1 and 55 RPB2 sequences from 69 individuals, focusing on the T. versicolor complex and performed phylogenetic analyses with maximum likelihood and parsimony methods. All three protein-coding genes outperformed ITS for separating species in the T. versicolor complex. The multigene phylogenetic analysis shows the highest amount of resolution and supported nodes separating T. ectypa, T. ochracea, T. pubescens and T. versicolor with strong support. In addition three slineages are resolved in the species complex of T. elegans. The T. elegans complex includes three species: T. elegans (based on material from Puerto Rico, Belize, the Philippines), T. aesculi (from North America) and T. repanda (from Papua New Guinea, the Philippines, Venezuela). The utility of gene markers varies, with TEF1 having the highest PCR and sequencing success rate and RPB1 offering the best backbone resolution for the genus. © 2014 by The Mycological Society of America.

  11. Storage of sparse files using parallel log-structured file system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bent, John M.; Faibish, Sorin; Grider, Gary

    A sparse file is stored without holes by storing a data portion of the sparse file using a parallel log-structured file system; and generating an index entry for the data portion, the index entry comprising a logical offset, physical offset and length of the data portion. The holes can be restored to the sparse file upon a reading of the sparse file. The data portion can be stored at a logical end of the sparse file. Additional storage efficiency can optionally be achieved by (i) detecting a write pattern for a plurality of the data portions and generating a singlemore » patterned index entry for the plurality of the patterned data portions; and/or (ii) storing the patterned index entries for a plurality of the sparse files in a single directory, wherein each entry in the single directory comprises an identifier of a corresponding sparse file.« less

  12. Duox, Flotillin-2, and Src42A Are Required to Activate or Delimit the Spread of the Transcriptional Response to Epidermal Wounds in Drosophila

    PubMed Central

    Juarez, Michelle T.; Patterson, Rachel A.; Sandoval-Guillen, Efren; McGinnis, William

    2011-01-01

    The epidermis is the largest organ of the body for most animals, and the first line of defense against invading pathogens. A breach in the epidermal cell layer triggers a variety of localized responses that in favorable circumstances result in the repair of the wound. Many cellular and genetic responses must be limited to epidermal cells that are close to wounds, but how this is regulated is still poorly understood. The order and hierarchy of epidermal wound signaling factors are also still obscure. The Drosophila embryonic epidermis provides an excellent system to study genes that regulate wound healing processes. We have developed a variety of fluorescent reporters that provide a visible readout of wound-dependent transcriptional activation near epidermal wound sites. A large screen for mutants that alter the activity of these wound reporters has identified seven new genes required to activate or delimit wound-induced transcriptional responses to a narrow zone of cells surrounding wound sites. Among the genes required to delimit the spread of wound responses are Drosophila Flotillin-2 and Src42A, both of which are transcriptionally activated around wound sites. Flotillin-2 and constitutively active Src42A are also sufficient, when overexpressed at high levels, to inhibit wound-induced transcription in epidermal cells. One gene required to activate epidermal wound reporters encodes Dual oxidase, an enzyme that produces hydrogen peroxide. We also find that four biochemical treatments (a serine protease, a Src kinase inhibitor, methyl-ß-cyclodextrin, and hydrogen peroxide) are sufficient to globally activate epidermal wound response genes in Drosophila embryos. We explore the epistatic relationships among the factors that induce or delimit the spread of epidermal wound signals. Our results define new genetic functions that interact to instruct only a limited number of cells around puncture wounds to mount a transcriptional response, mediating local repair and

  13. 49 CFR 564.5 - Information filing; agency processing of filings.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 6 2010-10-01 2010-10-01 false Information filing; agency processing of filings... HIGHWAY TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REPLACEABLE LIGHT SOURCE INFORMATION (Eff. until 12-01-12) § 564.5 Information filing; agency processing of filings. (a) Each manufacturer...

  14. The Mycetophila ruficollis Meigen (Diptera, Mycetophilidae) group in Europe: elucidating species delimitation with COI and ITS2 sequence data

    PubMed Central

    Jürgenstein, Siiri; Kurina, Olavi; Põldmaa, Kadri

    2015-01-01

    Abstract European species of the Mycetophila ruficollis group are compared on the basis of morphology and sequences of mitochondrial cytochrome oxidase subunit one (COI) and the ITS2 region of nuclear ribosomal DNA. The study represents the first evaluation of morphology-based species delimitation of closely related fungus gnat species by applying molecular information. Detailed descriptions and illustrations of the male terminalia are presented along with a key for the identification of all nine European species of the group. Phylogenetic analyses of molecular data generally supported the morphological species discrimination. The barcoding region of COI superseded ITS2 rDNA in resolving species. In the COI barcoding region interspecific differences ranged from 2.9 to 10.6% and the intraspecific distance from 0.08 to 0.8%. Only COI data distinguished between the similar and closely related Mycetophila ichneumonea and Mycetophila uninotata of which the latter was observed to include cryptic species. The host range of some species is suggested to be narrower than previously considered and to depend on the forest type. Presented evidence indicates the importance of analysing sequence data of morphologically very similar mycetophages reared from identified host fungi for elucidating species delimitation as well as their geographic and host ranges. New country records, viz. Estonia for Mycetophila evanida, Georgia for Mycetophila ichneumonea, Mycetophila idonea and Mycetophila ruficollis, and Norway for Mycetophila strobli, widen the known distribution ranges of these species. PMID:26167119

  15. Texas Assessment of Basic Skills (TABS). Austin Independent School District. Final Report, 1985.

    ERIC Educational Resources Information Center

    Defino, Maria E.

    This report presents the Austin (Texas) Independent School District's 1985 test results on the Texas Assessment of Basic Skills (TABS). It was administered to all third, fifth, and ninth grade students and to high school students not meeting ninth grade state-set mastery criteria, the minimum competency requirement for graduation. Results are…

  16. The unholy trinity: taxonomy, species delimitation and DNA barcoding

    PubMed Central

    DeSalle, Rob; Egan, Mary G; Siddall, Mark

    2005-01-01

    Recent excitement over the development of an initiative to generate DNA sequences for all named species on the planet has in our opinion generated two major areas of contention as to how this ‘DNA barcoding’ initiative should proceed. It is critical that these two issues are clarified and resolved, before the use of DNA as a tool for taxonomy and species delimitation can be universalized. The first issue concerns how DNA data are to be used in the context of this initiative; this is the DNA barcode reader problem (or barcoder problem). Currently, many of the published studies under this initiative have used tree building methods and more precisely distance approaches to the construction of the trees that are used to place certain DNA sequences into a taxonomic context. The second problem involves the reaction of the taxonomic community to the directives of the ‘DNA barcoding’ initiative. This issue is extremely important in that the classical taxonomic approach and the DNA approach will need to be reconciled in order for the ‘DNA barcoding’ initiative to proceed with any kind of community acceptance. In fact, we feel that DNA barcoding is a misnomer. Our preference is for the title of the London meetings—Barcoding Life. In this paper we discuss these two concerns generated around the DNA barcoding initiative and attempt to present a phylogenetic systematic framework for an improved barcoder as well as a taxonomic framework for interweaving classical taxonomy with the goals of ‘DNA barcoding’. PMID:16214748

  17. User's Guide for the Updated EST/BEST Software System

    NASA Technical Reports Server (NTRS)

    Shah, Ashwin

    2003-01-01

    This User's Guide describes the structure of the IPACS input file that reflects the modularity of each module. The structured format helps the user locate specific input data and manually enter or edit it. The IPACS input file can have any user-specified filename, but must have a DAT extension. The input file may consist of up to six input data blocks; the data blocks must be separated by delimiters beginning with the $ character. If multiple sections are desired, they must be arranged in the order listed.

  18. n-Gram-Based Text Compression.

    PubMed

    Nguyen, Vu H; Nguyen, Hien T; Duong, Hieu N; Snasel, Vaclav

    2016-01-01

    We propose an efficient method for compressing Vietnamese text using n -gram dictionaries. It has a significant compression ratio in comparison with those of state-of-the-art methods on the same dataset. Given a text, first, the proposed method splits it into n -grams and then encodes them based on n -gram dictionaries. In the encoding phase, we use a sliding window with a size that ranges from bigram to five grams to obtain the best encoding stream. Each n -gram is encoded by two to four bytes accordingly based on its corresponding n -gram dictionary. We collected 2.5 GB text corpus from some Vietnamese news agencies to build n -gram dictionaries from unigram to five grams and achieve dictionaries with a size of 12 GB in total. In order to evaluate our method, we collected a testing set of 10 different text files with different sizes. The experimental results indicate that our method achieves compression ratio around 90% and outperforms state-of-the-art methods.

  19. n-Gram-Based Text Compression

    PubMed Central

    Duong, Hieu N.; Snasel, Vaclav

    2016-01-01

    We propose an efficient method for compressing Vietnamese text using n-gram dictionaries. It has a significant compression ratio in comparison with those of state-of-the-art methods on the same dataset. Given a text, first, the proposed method splits it into n-grams and then encodes them based on n-gram dictionaries. In the encoding phase, we use a sliding window with a size that ranges from bigram to five grams to obtain the best encoding stream. Each n-gram is encoded by two to four bytes accordingly based on its corresponding n-gram dictionary. We collected 2.5 GB text corpus from some Vietnamese news agencies to build n-gram dictionaries from unigram to five grams and achieve dictionaries with a size of 12 GB in total. In order to evaluate our method, we collected a testing set of 10 different text files with different sizes. The experimental results indicate that our method achieves compression ratio around 90% and outperforms state-of-the-art methods. PMID:27965708

  20. Fitting C 2 Continuous Parametric Surfaces to Frontiers Delimiting Physiologic Structures

    PubMed Central

    Bayer, Jason D.

    2014-01-01

    We present a technique to fit C 2 continuous parametric surfaces to scattered geometric data points forming frontiers delimiting physiologic structures in segmented images. Such mathematical representation is interesting because it facilitates a large number of operations in modeling. While the fitting of C 2 continuous parametric curves to scattered geometric data points is quite trivial, the fitting of C 2 continuous parametric surfaces is not. The difficulty comes from the fact that each scattered data point should be assigned a unique parametric coordinate, and the fit is quite sensitive to their distribution on the parametric plane. We present a new approach where a polygonal (quadrilateral or triangular) surface is extracted from the segmented image. This surface is subsequently projected onto a parametric plane in a manner to ensure a one-to-one mapping. The resulting polygonal mesh is then regularized for area and edge length. Finally, from this point, surface fitting is relatively trivial. The novelty of our approach lies in the regularization of the polygonal mesh. Process performance is assessed with the reconstruction of a geometric model of mouse heart ventricles from a computerized tomography scan. Our results show an excellent reproduction of the geometric data with surfaces that are C 2 continuous. PMID:24782911

  1. Delimitation of some neotropical laccate Ganoderma (Ganodermataceae): molecular phylogeny and morphology.

    PubMed

    De Lima Júnior, Nelson Correia; Baptista Gibertone, Tatiana; Malosso, Elaine

    2014-09-01

    Ganoderma includes species of great economic and ecological importance, but taxonomists judge the current nomenclatural situation as chaotic and poorly studied in the neotropics. From this perspective, phylogenetic analyses inferred from ribosomal DNA sequences have aided the clarification of the genus status. In this study, 14 specimens of Ganoderma and two of Tomophagus collected in Brazil were used for DNA extraction, amplification and sequencing of the ITS and LSU regions (rDNA). The phylogenetic delimitation of six neotropical taxa (G. chalceum, G. multiplicatum, G. orbiforme, G. parvulum, G. aff. oerstedtii and Tomophagus colossus) was determined based on these Brazilian specimens and found to be distinct from the laccate Ganoderma from Asia, Europe, North America and from some specimens from Argentina. Phylogenetic reconstructions confirmed that the laccate Ganoderna is distinct from Tomophagus, although they belong to the same group. The use of taxonomic synonyms Ganoderma subamboinense for G. multiplicatumnz, G. boninense for G. orbiforme and G. chalceum for G. cupreum was not confirmed. However, Ganoderma parvulum was confirmed as the correct name for specimens called G. stipitatu. Furthermore, the name G. hucidumn should be used only for European species. The use of valid published names is proposed according to the specimen geographical distribution, their morphological characteristics and rDNA analysis. 1208. Epub 2014 September 01.

  2. Improved fatigue performance for wood-based structural panels using slot and tab construction

    Treesearch

    Jinghao Li; John F. Hunt; Shaoqin Gong; Zhiyong Cai

    2016-01-01

    This paper presents static and fatigue bending behavior for a wood-based structural panel having a slot and tab (S/T) construction technique. Comparisons were made with similarly fabricated panels without the S/T construction technique. Experimental results showed that both types of panels had similar bending properties in the static tests. However, the panels with S/T...

  3. Impact of species delimitation and sampling on niche models and phylogeographical inference: A case study of the East African reed frog Hyperolius substriatus Ahl, 1931.

    PubMed

    Bittencourt-Silva, Gabriela B; Lawson, Lucinda P; Tolley, Krystal A; Portik, Daniel M; Barratt, Christopher D; Nagel, Peter; Loader, Simon P

    2017-09-01

    Ecological niche models (ENMs) have been used in a wide range of ecological and evolutionary studies. In biogeographic studies these models have, among other things, helped in the discovery of new allopatric populations, and even new species. However, small sample sizes and questionable taxonomic delimitation can challenge models, often decreasing their accuracy. Herein we examine the sensitivity of ENMs to the addition of new, geographically isolated populations, and the impact of applying different taxonomic delimitations. The East African reed frog Hyperolius substriatus Ahl, 1931 was selected as a case study because it has been the subject of previous ENM predictions. Our results suggest that addition of new data and reanalysis of species lineages of H. substriatus improved our understanding of the evolutionary history of this group of frogs. ENMs provided robust predictions, even when some populations were deliberately excluded from the models. Splitting the lineages based on genetic relationships and analysing the ENMs separately provided insights about the biogeographical processes that led to the current distribution of H. substriatus. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. Single-locus species delimitation: a test of the mixed Yule-coalescent model, with an empirical application to Philippine round-leaf bats.

    PubMed

    Esselstyn, Jacob A; Evans, Ben J; Sedlock, Jodi L; Anwarali Khan, Faisal Ali; Heaney, Lawrence R

    2012-09-22

    Prospects for a comprehensive inventory of global biodiversity would be greatly improved by automating methods of species delimitation. The general mixed Yule-coalescent (GMYC) was recently proposed as a potential means of increasing the rate of biodiversity exploration. We tested this method with simulated data and applied it to a group of poorly known bats (Hipposideros) from the Philippines. We then used echolocation call characteristics to evaluate the plausibility of species boundaries suggested by GMYC. In our simulations, GMYC performed relatively well (errors in estimated species diversity less than 25%) when the product of the haploid effective population size (N(e)) and speciation rate (SR; per lineage per million years) was less than or equal to 10(5), while interspecific variation in N(e) was twofold or less. However, at higher but also biologically relevant values of N(e) × SR and when N(e) varied tenfold among species, performance was very poor. GMYC analyses of mitochondrial DNA sequences from Philippine Hipposideros suggest actual diversity may be approximately twice the current estimate, and available echolocation call data are mostly consistent with GMYC delimitations. In conclusion, we consider the GMYC model useful under some conditions, but additional information on N(e), SR and/or corroboration from independent character data are needed to allow meaningful interpretation of results.

  5. Species delimitation in downy mildews: the case of Hyaloperonospora in the light of nuclear ribosomal ITS and LSU sequences.

    PubMed

    Göker, Markus; Voglmayr, Hermann; Blázquez, Gema García; Oberwinkler, Franz

    2009-03-01

    Species definitions for plant pathogens have considerable practical impact for measures such as plant protection or biological control, and are also important for comparative studies involving model organisms. However, in many groups, the delimitation of species is a notoriously difficult taxonomic problem. This is particularly evident in the obligate biotrophic downy mildew genera (Peronosporaceae, Peronosporales, Oomycetes), which display a considerable diversity with respect to genetic distances and host plants, but are, for the most part, morphologically rather uniform. The recently established genus Hyaloperonospora is of particular biological interest because it shows an impressive radiation on virtually a single host family, Brassicaceae, and it contains the downy mildew parasite, Arabidopsis thaliana, of importance as a model organism. Based on the most comprehensive molecular sampling of specimens from a downy mildew genus to date, including various collections from different host species and geographic locations, we investigate the phylogenetic relationships of Hyaloperonospora by molecular analysis of the nuclear ribosomal ITS and LSU sequences. Phylogenetic trees were inferred with ML and MP from the combined dataset; partitioned Bremer support (PBrS) was used to assess potential conflict between data partitions. As in other downy mildew groups, the molecular data clearly corroborate earlier results that supported the use of narrow species delimitations and host ranges as taxonomic markers. With few exceptions, suggested species boundaries are supported without conflict between different data partitions. The results indicate that a combination of molecular and host features is a reliable means to discriminate downy mildew species for which morphological differences are unknown.

  6. 78 FR 17394 - Filing via the Internet; Electronic Tariff Filings; Revisions to Electric Quarterly Report Filing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-21

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket Nos. RM07-16-000; RM01-5-000; RM12-3-000] Filing via the Internet; Electronic Tariff Filings; Revisions to Electric Quarterly Report Filing Process; Notice of Technical Conference Take notice that on April 16, 2013, the staff of the...

  7. Text Mining Metal-Organic Framework Papers.

    PubMed

    Park, Sanghoon; Kim, Baekjun; Choi, Sihoon; Boyd, Peter G; Smit, Berend; Kim, Jihan

    2018-02-26

    We have developed a simple text mining algorithm that allows us to identify surface area and pore volumes of metal-organic frameworks (MOFs) using manuscript html files as inputs. The algorithm searches for common units (e.g., m 2 /g, cm 3 /g) associated with these two quantities to facilitate the search. From the sample set data of over 200 MOFs, the algorithm managed to identify 90% and 88.8% of the correct surface area and pore volume values. Further application to a test set of randomly chosen MOF html files yielded 73.2% and 85.1% accuracies for the two respective quantities. Most of the errors stem from unorthodox sentence structures that made it difficult to identify the correct data as well as bolded notations of MOFs (e.g., 1a) that made it difficult identify its real name. These types of tools will become useful when it comes to discovering structure-property relationships among MOFs as well as collecting a large set of data for references.

  8. Registered File Support for Critical Operations Files at (Space Infrared Telescope Facility) SIRTF

    NASA Technical Reports Server (NTRS)

    Turek, G.; Handley, Tom; Jacobson, J.; Rector, J.

    2001-01-01

    The SIRTF Science Center's (SSC) Science Operations System (SOS) has to contend with nearly one hundred critical operations files via comprehensive file management services. The management is accomplished via the registered file system (otherwise known as TFS) which manages these files in a registered file repository composed of a virtual file system accessible via a TFS server and a file registration database. The TFS server provides controlled, reliable, and secure file transfer and storage by registering all file transactions and meta-data in the file registration database. An API is provided for application programs to communicate with TFS servers and the repository. A command line client implementing this API has been developed as a client tool. This paper describes the architecture, current implementation, but more importantly, the evolution of these services based on evolving community use cases and emerging information system technology.

  9. Engaging Learners through Artmaking: Choice-Based Art Education in the Classroom (TAB). Second Edition

    ERIC Educational Resources Information Center

    Douglas, Katherine M.; Jaquith, Diane B.

    2018-01-01

    The authors who introduced the concepts of Teaching for Artistic Behavior (TAB) and choice-based art education have completely revised and updated their original, groundbreaking bestseller that was designed to facilitate independent learning and support student choices in subject matter and media. More than ever before, teachers are held…

  10. Highway Safety Information System guidebook for the Minnesota state data files. Volume 1 : SAS file formats

    DOT National Transportation Integrated Search

    2001-02-01

    The Minnesota data system includes the following basic files: Accident data (Accident File, Vehicle File, Occupant File); Roadlog File; Reference Post File; Traffic File; Intersection File; Bridge (Structures) File; and RR Grade Crossing File. For ea...

  11. Species Delimitation in the Genus Moschus (Ruminantia: Moschidae) and Its High-Plateau Origin.

    PubMed

    Pan, Tao; Wang, Hui; Hu, Chaochao; Sun, Zhonglou; Zhu, Xiaoxue; Meng, Tao; Meng, Xiuxiang; Zhang, Baowei

    2015-01-01

    The authenticity of controversial species is a significant challenge for systematic biologists. Moschidae is a small family of musk deer in the Artiodactyla, composing only one genus, Moschus. Historically, the number of species in the Moschidae family has been debated. Presently, most musk deer species were restricted in the Tibetan Plateau and surrounding/adjacent areas, which implied that the evolution of Moschus might have been punctuated by the uplift of the Tibetan Plateau. In this study, we aimed to determine the evolutionary history and delimit the species in Moschus by exploring the complete mitochondrial genome (mtDNA) and other mitochondrial gene. Our study demonstrated that six species, M. leucogaster, M. fuscus, M. moschiferus, M. berezovskii, M. chrysogaster and M. anhuiensis, were authentic species in the genus Moschus. Phylogenetic analysis and molecular dating showed that the ancestor of the present Moschidae originates from Tibetan Plateau which suggested that the evolution of Moschus was prompted by the most intense orogenic movement of the Tibetan Plateau during the Pliocene age, and alternating glacial-interglacial geological eras.

  12. Database citation in supplementary data linked to Europe PubMed Central full text biomedical articles.

    PubMed

    Kafkas, Şenay; Kim, Jee-Hyub; Pi, Xingjun; McEntyre, Johanna R

    2015-01-01

    In this study, we present an analysis of data citation practices in full text research articles and their corresponding supplementary data files, made available in the Open Access set of articles from Europe PubMed Central. Our aim is to investigate whether supplementary data files should be considered as a source of information for integrating the literature with biomolecular databases. Using text-mining methods to identify and extract a variety of core biological database accession numbers, we found that the supplemental data files contain many more database citations than the body of the article, and that those citations often take the form of a relatively small number of articles citing large collections of accession numbers in text-based files. Moreover, citation of value-added databases derived from submission databases (such as Pfam, UniProt or Ensembl) is common, demonstrating the reuse of these resources as datasets in themselves. All the database accession numbers extracted from the supplementary data are publicly accessible from http://dx.doi.org/10.5281/zenodo.11771. Our study suggests that supplementary data should be considered when linking articles with data, in curation pipelines, and in information retrieval tasks in order to make full use of the entire research article. These observations highlight the need to improve the management of supplemental data in general, in order to make this information more discoverable and useful.

  13. 75 FR 54059 - Extension of Filing Accommodation for Static Pool Information in Filings With Respect to Asset...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-03

    ... information could include a significant amount of statistical information that would be difficult to file... required static pool information. Given the large amount of statistical information involved, commentators....; and 18 U.S.C. 1350. * * * * * 2. Amend Sec. 232.312 paragraph (a) introductory text by removing...

  14. Digital seismic-reflection data from western Rhode Island Sound, 1980

    USGS Publications Warehouse

    McMullen, K.Y.; Poppe, L.J.; Soderberg, N.K.

    2009-01-01

    During 1980, the U.S. Geological Survey (USGS) conducted a seismic-reflection survey in western Rhode Island Sound aboard the Research Vessel Neecho. Data from this survey were recorded in analog form and archived at the USGS Woods Hole Science Center's Data Library. Due to recent interest in the geology of Rhode Island Sound and in an effort to make the data more readily accessible while preserving the original paper records, the seismic data from this cruise were scanned and converted to Tagged Image File Format (TIFF) images and SEG-Y data files. Navigation data were converted from U.S. Coast Guard Long Range Aids to Navigation (LORAN-C) time delays to latitudes and longitudes, which are available in Environmental Systems Research Institute, Inc. (ESRI) shapefile format and as eastings and northings in space-delimited text format.

  15. Storing files in a parallel computing system using list-based index to identify replica files

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Faibish, Sorin; Bent, John M.; Tzelnic, Percy

    Improved techniques are provided for storing files in a parallel computing system using a list-based index to identify file replicas. A file and at least one replica of the file are stored in one or more storage nodes of the parallel computing system. An index for the file comprises at least one list comprising a pointer to a storage location of the file and a storage location of the at least one replica of the file. The file comprises one or more of a complete file and one or more sub-files. The index may also comprise a checksum value formore » one or more of the file and the replica(s) of the file. The checksum value can be evaluated to validate the file and/or the file replica(s). A query can be processed using the list.« less

  16. 43 CFR 4.1362 - Where to file; when to file.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... APPEALS PROCEDURES Special Rules Applicable to Surface Coal Mining Hearings and Appeals Request for Review... Transfer, Assignment Or Sale of Rights Granted Under Permit (federal Program; Federal Lands Program... file; when to file. (a) The request for review shall be filed with the Hearings Division, Office of...

  17. PCF File Format.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Thoreson, Gregory G

    PCF files are binary files designed to contain gamma spectra and neutron count rates from radiation sensors. It is the native format for the GAmma Detector Response and Analysis Software (GADRAS) package [1]. It can contain multiple spectra and information about each spectrum such as energy calibration. This document outlines the format of the file that would allow one to write a computer program to parse and write such files.

  18. Improvements to the Magnetics Information Consortium (MagIC) Paleo and Rock Magnetic Database

    NASA Astrophysics Data System (ADS)

    Jarboe, N.; Minnett, R.; Tauxe, L.; Koppers, A. A. P.; Constable, C.; Jonestrask, L.

    2015-12-01

    The Magnetic Information Consortium (MagIC) database (http://earthref.org/MagIC/) continues to improve the ease of data uploading and editing, the creation of complex searches, data visualization, and data downloads for the paleomagnetic, geomagnetic, and rock magnetic communities. Online data editing is now available and the need for proprietary spreadsheet software is therefore entirely negated. The data owner can change values in the database or delete entries through an HTML 5 web interface that resembles typical spreadsheets in behavior and uses. Additive uploading now allows for additions to data sets to be uploaded with a simple drag and drop interface. Searching the database has improved with the addition of more sophisticated search parameters and with the facility to use them in complex combinations. A comprehensive summary view of a search result has been added for increased quick data comprehension while a raw data view is available if one desires to see all data columns as stored in the database. Data visualization plots (ARAI, equal area, demagnetization, Zijderveld, etc.) are presented with the data when appropriate to aid the user in understanding the dataset. MagIC data associated with individual contributions or from online searches may be downloaded in the tab delimited MagIC text file format for susbsequent offline use and analysis. With input from the paleomagnetic, geomagnetic, and rock magnetic communities, the MagIC database will continue to improve as a data warehouse and resource.

  19. Changing Names with Changed Address: Integrated Taxonomy and Species Delimitation in the Holarctic Colymbetes paykulli Group (Coleoptera: Dytiscidae)

    PubMed Central

    Drotz, Marcus K.; Brodin, Tomas; Nilsson, Anders N.

    2015-01-01

    Species delimitation of geographically isolated forms is a long-standing problem in less studied insect groups. Often taxonomic decisions are based directly on morphologic variation, and lack a discussion regarding sample size and the efficiency of migration barriers or dispersal/migration capacity of the studied species. These problems are here exemplified in a water beetle complex from the Bering Sea region that separates North America from Eurasia. Only a few sampled specimens occur from this particular area and they are mostly found in museum and private collections. Here we utilize the theory of integrated taxonomy to discuss the speciation of the Holarctic Colymbetes paykulli water beetle complex, which historically has included up to five species of which today only two are recognized. Three delimitation methods are used; landmark based morphometry of body shape, variation in reticulation patterns of the pronotum exo-skeleton and sequence variation of the partial mitochondrial gene Cyt b. Our conclusion is that the Palearctic and Nearctic populations of C. paykulli are given the status of separate species, based on the fact that all methods showed significant separation between populations. As a consequence the name of the Palearctic species is C. paykulli Erichson and the Nearctic species should be known as C. longulus LeConte. There is no clear support for delineation between Palearctic and Nearctic populations of C. dahuricus based on mtDNA. However, significant difference in size and reticulation patterns from the two regions is shown. The combined conclusion is that the C. dahuricus complex needs a more thorough investigation to fully disentangle its taxonomic status. Therefore it is here still regarded as a Holarctic species. This study highlights the importance to study several diagnosable characters that has the potential to discriminate evolutionary lineage during speciation. PMID:26619278

  20. PDBToSDF: Create ligand structure files from PDB file.

    PubMed

    Muppalaneni, Naresh Babu; Rao, Allam Appa

    2011-01-01

    Protein Data Bank (PDB) file contains atomic data for protein and ligand in protein-ligand complexes. Structure data file (SDF) contains data for atoms, bonds, connectivity and coordinates of molecule for ligands. We describe PDBToSDF as a tool to separate the ligand data from pdb file for the calculation of ligand properties like molecular weight, number of hydrogen bond acceptors, hydrogen bond receptors easily.

  1. Wheat bHLH-type transcription factor gene TabHLH1 is crucial in mediating osmotic stresses tolerance through modulating largely the ABA-associated pathway.

    PubMed

    Yang, Tongren; Yao, Sufei; Hao, Lin; Zhao, Yuanyuan; Lu, Wenjing; Xiao, Kai

    2016-11-01

    Wheat bHLH family gene TabHLH1 is responsive to drought and salt stresses, and it acts as one crucial regulator in mediating tolerance to aforementioned stresses largely through an ABA-associated pathway. Osmotic stresses are adverse factors for plant growth and crop productivity. In this study, we characterized TabHLH1, a gene encoding wheat bHLH-type transcription factor (TF) protein, in mediating plant adaptation to osmotic stresses. TabHLH1 protein contains a conserved basic-helix-loop-helix (bHLH) domain shared by its plant counterparts. Upon PEG-simulated drought stress, salt stress, and exogenous abscisic acid (ABA), the TabHLH1 transcripts in roots and leaves were induced. Under PEG-simulated drought stress and salt stress treatments, the tobacco seedlings with TabHLH1 overexpression exhibited improved growth and osmotic stress-associated traits, showing increased biomass and reduced leaf water loss rate (WLR) relative to wild type (WT). The transgenic lines also possessed promoted stomata closure under drought stress, salt stress, and exogenous ABA and increased proline and soluble sugar contents and reduced hydrogen peroxide (H 2 O 2 ) amount under osmotic stress conditions, indicating that TabHLH1-mediated osmolyte accumulation and cellular ROS homeostasis contributed to the drought stress and salt stress tolerance. NtPYL12 and NtSAPK2;1, the genes encoding ABA receptor and SnRK2 family kinase, respectively, showed up-regulated expression in lines overexpressing TabHLH1 under osmotic stress and exogenous ABA conditions; overexpression of them conferred plants modified stomata movement, leaf WLR, and growth feature under drought and high salinity, suggesting that these ABA-signaling genes are mediated by wheat TabHLH1 gene and involved in regulating plant responses to simulated drought and salt stresses. Our investigation indicates that the TabHLH1 gene plays critical roles in plant tolerance to osmotic stresses largely through an ABA-dependent pathway.

  2. Files in /noaa/dhs

    Science.gov Websites

    noaa_20110510_wbg.gif 10-May-2011 20:58 31K generic file noaa_20110510_wbg.pdf 10-May-2011 20:58 128K generic file noaa_20110513_wbg.gif 13-May-2011 20:10 27K generic file noaa_20110513_wbg.pdf 13-May-2011 20:10 122K generic file noaa_20110518_wbg.gif 18-May-2011 21:10 33K generic file noaa_20110518_wbg.pdf 18-May-2011 21:10 128K generic file

  3. Text to Speech (TTS) Capabilities for the Common Driver Trainer (CDT)

    DTIC Science & Technology

    2010-10-01

    harnessing in’leigle jalClpeno jocelyn linu ~ los angeles lottery margarine mathematlze mathematized mathematized meme memes memol...including Julie, Kate, and Paul . Based upon the names of the voices, it may be that the VoiceText capability is the technology being used currently on...DFTTSExportToFileEx(O, " Paul ", 1, 1033, "Testing the Digital Future Text-to-Speech SDK.", -1, -1, -1, -1, -1, DFTTS_ TEXT_ TYPE_ XML, "test.wav", 0, "", -1

  4. Task-Oriented Access to Data Files: An Evaluation.

    ERIC Educational Resources Information Center

    Watters, Carolyn; And Others

    1994-01-01

    Discussion of information retrieval highlights DalText, a prototype information retrieval system that provides access to nonindexed textual data files where the mode of access is determined by the user based on the task at hand. A user study is described that was conducted at Dalhousie University (Nova Scotia) to test DalText. (Contains 23…

  5. Shear flow control of cold and heated rectangular jets by mechanical tabs. Volume 2: Tabulated data

    NASA Technical Reports Server (NTRS)

    Brown, W. H.; Ahuja, K. K.

    1989-01-01

    The effects of mechanical protrusions on the jet mixing characteristics of rectangular nozzles for heated and unheated subsonic and supersonic jet plumes were studied. The characteristics of a rectangular nozzle of aspect ratio 4 without the mechanical protrusions were first investigated. Intrusive probes were used to make the flow measurements. Possible errors introduced by intrusive probes in making shear flow measurements were also examined. Several scaled sizes of mechanical tabs were then tested, configured around the perimeter of the rectangular jet. Both the number and the location of the tabs were varied. From this, the best configuration was selected. This volume contains tabulated data for each of the data runs cited in Volume 1. Baseline characteristics, mixing modifications (subsonic and supersonic, heated and unheated) and miscellaneous charts are included.

  6. Document Delivery from Full-Text Online Files: A Pilot Project.

    ERIC Educational Resources Information Center

    Gillikin, David P.

    1990-01-01

    Describes the Electronic Journal Retrieval Project (EJRP) developed at the University of Tennessee, Knoxville Libraries, to provide full-text journal articles from online systems. Highlights include costs of various search strategies; implications for library services; collection development and interlibrary loan considerations; and suggestions…

  7. Runwien: a text-based interface for the WIEN package

    NASA Astrophysics Data System (ADS)

    Otero de la Roza, A.; Luaña, Víctor

    2009-05-01

    A new text-based interface for WIEN2k, the full-potential linearized augmented plane-waves (FPLAPW) program, is presented. This code provides an easy to use, yet powerful way of generating arbitrarily large sets of calculations. Thus, properties over a potential energy surface and WIEN2k parameter exploration can be calculated using a simple input text file. This interface also provides new capabilities to the WIEN2k package, such as the calculation of elastic constants on hexagonal systems or the automatic gathering of relevant information. Additionally, runwien is modular, flexible and intuitive. Program summaryProgram title: runwien Catalogue identifier: AECM_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AECM_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: GPL version 3 No. of lines in distributed program, including test data, etc.: 62 567 No. of bytes in distributed program, including test data, etc.: 610 973 Distribution format: tar.gz Programming language: gawk (with locale POSIX or similar) Computer: All running Unix, Linux Operating system: Unix, GNU/Linux Classification: 7.3 External routines: WIEN2k ( http://www.wien2k.at/), GAWK ( http://www.gnu.org/software/gawk/), rename by L. Wall, a Perl script which renames files, modified by R. Barker to check for the existence of target files, gnuplot ( http://www.gnuplot.info/) Subprograms used:Cat Id: ADSY_v1_0/AECB_v1_0, Title: GIBBS/CRITIC, Reference: CPC 158 (2004) 57/CPC 999 (2009) 999 Nature of problem: Creation of a text-based, batch-oriented interface for the WIEN2k package. Solution method: WIEN2k solves the Kohn-Sham equations of a solid using the FPLAPW formalism. Runwien interprets an input file containing the description of the geometry and structure of the solid and drives the execution of the WIEN2k programs. The input is simplified thanks to the default values of the WIEN2k parameters known to runwien. Additional

  8. The Study and Implementation of Text-to-Speech System for Agricultural Information

    NASA Astrophysics Data System (ADS)

    Zheng, Huoguo; Hu, Haiyan; Liu, Shihong; Meng, Hong

    The Broadcast and Television coverage has increased to more than 98% in china. Information services by radio have wide coverage, low cost, easy-to-grass-roots farmers to accept etc. characteristics. In order to play the better role of broadcast information service, as well as aim at the problem of lack of information resource in rural, we R & D the text-to-speech system. The system includes two parts, software and hardware device, both of them can translate text into audio file. The software subsystem was implemented basic on third-part middleware, and the hardware subsystem was realized with microelectronics technology. Results indicate that the hardware is better than software. The system has been applied in huailai city hebei province, which has conversed more than 8000 audio files as programming materials for the local radio station.

  9. Storage-based Intrusion Detection: Watching storage activity for suspicious behavior

    DTIC Science & Technology

    2002-10-01

    password management involves a pair of inter-related files (/etc/ passwd and /etc/shadow). The corresponding access pat- terns seen at the storage...example, consider a UNIX system password file (/etc/ passwd ), which con- sists of a set of well-defined records. Records are delimited by a line-break, and...etc/ passwd and verify that they conform to a set of basic integrity rules: 7-field records, non-empty password field, legal default shell, legal home

  10. Vulnerability of groundwater resources to nitrate pollution: A simple and effective procedure for delimiting Nitrate Vulnerable Zones.

    PubMed

    Arauzo, Mercedes

    2017-01-01

    This research was undertaken to further our understanding of the factors involved in nonpoint-source nitrate pollution of groundwater. The shortcomings of some of the most commonly used methods for assessing groundwater vulnerability have been analysed and a new procedure that incorporates key improvements has been proposed. The new approach (LU-IV procedure) allows us to assess and map groundwater vulnerability to nitrate pollution and to accurately delimit the Nitrate Vulnerable Zones. The LU-IV procedure proved more accurate than the most widely used methods to assess groundwater vulnerability (DRASTIC, GOD), when compared with nitrate distribution in the groundwater of 46 aquifers included in the study (using the drainage basin as the unit of analysis). The proposed procedure stands out by meeting the following requirements: (1) it uses readily available parameters that provide enough data to feed the model, (2) it excludes redundant parameters, (3) it avoids the need to assign insufficiently contrasted weights to parameters, (4) it assess the whole catchment area that potentially drains N-polluted waters into the receptor aquifer, (5) it can be implemented within a GIS, and (6) it provides a multi-scale representation. As the LU-IV procedure has been demonstrated to be a reliable tool for delimiting NVZ, it could be particularly interesting to use it in countries where certain types of environmental data are either not available or have only limited availability. Based on this study (and according to the LU-IV procedure), it was concluded that an area of at least 1728km 2 should be considered as NVZ. This sharply contrasts with the current 328km 2 officially designated in the study area by the Spain's regional administrations. These results highlight the need to redefine the current NVZ designation, which is essential for an appropriate implementation of action programmes designed to restore water quality in line with Directive 91/676/EEC. Copyright © 2016

  11. 49 CFR 387.323 - Electronic filing of surety bonds, trust fund agreements, certificates of insurance and...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Description RequiredF=filing C=cancel B=both Start field End field Record type 1 Numeric 1=Filing 2=Cancellation B 1 1 Insurer number 8 Text FMCSA Assigned Insurer Number (Home Office) With Suffix (Issuing Office), If Different, e.g. 12345-01 B 2 9 Filing type 1 Numeric 1 = BI&PD 2 = Cargo 3 = Bond 4 = Trust...

  12. 49 CFR 387.323 - Electronic filing of surety bonds, trust fund agreements, certificates of insurance and...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Description RequiredF=filing C=cancel B=both Start field End field Record type 1 Numeric 1=Filing 2=Cancellation B 1 1 Insurer number 8 Text FMCSA Assigned Insurer Number (Home Office) With Suffix (Issuing Office), If Different, e.g. 12345-01 B 2 9 Filing type 1 Numeric 1 = BI&PD 2 = Cargo 3 = Bond 4 = Trust...

  13. Species delimitation in the Grayling genus Pseudochazara (Lepidoptera, Nymphalidae, Satyrinae) supported by DNA barcodes

    PubMed Central

    Verovnik, Rudi; Wiemers, Martin

    2016-01-01

    Abstract The Palaearctic Grayling genus Pseudochazara encompasses a number of petrophilous butterfly species, most of which are local endemics especially in their centre of radiation in SW Asia and the Balkans. Due to a lack of consistent morphological characters, coupled with habitat induced variability, their taxonomy is poorly understood and species delimitation is hampered. We employed a DNA barcoding approach to address the question of separate species status for several European taxa and provide first insight into the phylogeny of the genus. Unexpectedly we found conflicting patterns with deep divergences between presumably conspecific taxa and lack of divergence among well-defined species. We propose separate species status for Pseudochazara tisiphone, Pseudochazara amalthea, Pseudochazara amymone, and Pseudochazara kermana all of which have separate well supported clades, with the majority of them becoming local endemics. Lack of resolution in the ‘Mamurra’ species group with well-defined species (in terms of wing pattern and coloration) such as Pseudochazara geyeri, Pseudochazara daghestana and Pseudochazara alpina should be further explored using nuclear molecular markers with higher genetic resolution. PMID:27408604

  14. 48 CFR 1652.204-72 - Filing health benefit claims/court review of disputed claims.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Filing health benefit... System OFFICE OF PERSONNEL MANAGEMENT FEDERAL EMPLOYEES HEALTH BENEFITS ACQUISITION REGULATION CLAUSES AND FORMS CONTRACT CLAUSES Texts of FEHBP Clauses 1652.204-72 Filing health benefit claims/court...

  15. 48 CFR 1652.204-72 - Filing health benefit claims/court review of disputed claims.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Filing health benefit... System OFFICE OF PERSONNEL MANAGEMENT FEDERAL EMPLOYEES HEALTH BENEFITS ACQUISITION REGULATION CLAUSES AND FORMS CONTRACT CLAUSES Texts of FEHBP Clauses 1652.204-72 Filing health benefit claims/court...

  16. 48 CFR 1652.204-72 - Filing health benefit claims/court review of disputed claims.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Filing health benefit... System OFFICE OF PERSONNEL MANAGEMENT FEDERAL EMPLOYEES HEALTH BENEFITS ACQUISITION REGULATION CLAUSES AND FORMS CONTRACT CLAUSES Texts of FEHBP Clauses 1652.204-72 Filing health benefit claims/court...

  17. 78 FR 60952 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ...-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing and Immediate... hereby given that, on September 24, 2013, Financial Industry Regulatory Authority, Inc. (``FINRA'') filed... discussed any comments it received on the proposed rule change. The text of these statements may be examined...

  18. 25 CFR 580.5 - What happens if I file late or fail to file?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false What happens if I file late or fail to file? 580.5 Section 580.5 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR APPEAL PROCEEDINGS... What happens if I file late or fail to file? (a) Failure to file an appeal within the time provided...

  19. 25 CFR 580.5 - What happens if I file late or fail to file?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 2 2014-04-01 2014-04-01 false What happens if I file late or fail to file? 580.5 Section 580.5 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR APPEAL PROCEEDINGS... What happens if I file late or fail to file? (a) Failure to file an appeal within the time provided...

  20. Register file soft error recovery

    DOEpatents

    Fleischer, Bruce M.; Fox, Thomas W.; Wait, Charles D.; Muff, Adam J.; Watson, III, Alfred T.

    2013-10-15

    Register file soft error recovery including a system that includes a first register file and a second register file that mirrors the first register file. The system also includes an arithmetic pipeline for receiving data read from the first register file, and error detection circuitry to detect whether the data read from the first register file includes corrupted data. The system further includes error recovery circuitry to insert an error recovery instruction into the arithmetic pipeline in response to detecting the corrupted data. The inserted error recovery instruction replaces the corrupted data in the first register file with a copy of the data from the second register file.

  1. 49 CFR 387.323 - Electronic filing of surety bonds, trust fund agreements, certificates of insurance and...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Start field End field Record type 1 Numeric 1=Filing2=Cancellation B 1 1 Insurer number 8 Text FMCSA... Filing type 1 Numeric 1 = BI&PD2 = Cargo 3 = Bond 4 = Trust Fund B 10 10 FMCSA docket number 8 Text FMCSA... 264 265 Insured zip code 9 Numeric (Do not include dash if using 9 digit code) B 266 274 Insured...

  2. 49 CFR 387.323 - Electronic filing of surety bonds, trust fund agreements, certificates of insurance and...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Start field End field Record type 1 Numeric 1=Filing2=Cancellation B 1 1 Insurer number 8 Text FMCSA... Filing type 1 Numeric 1 = BI&PD2 = Cargo 3 = Bond 4 = Trust Fund B 10 10 FMCSA docket number 8 Text FMCSA... 264 265 Insured zip code 9 Numeric (Do not include dash if using 9 digit code) B 266 274 Insured...

  3. Method and apparatus for mounting a dichroic mirror in a microwave powered lamp assembly using deformable tabs

    DOEpatents

    Ury, Michael; Sowers, Frank; Harper, Curt; Love, Wayne

    1998-01-01

    A microwave powered electrodeless lamp includes an improved screen unit having mesh and solid sections with an internal reflector secured at the juncture of the two sections to reflect light into a light-transmitting chamber defined in the lamp microwave cavity by the reflector and the mesh section. A discharge envelope of a bulb is disposed in the light-transmitting chamber. Light emitted from the envelope is prevented by the reflector from entering the cavity portion bounded by the solid section of the screen. The reflector is mounted in the cavity by tabs formed in the screen unit and bendable into the cavity to define support planes abutting respective surfaces of the reflector. The mesh section and tabs are preferably formed by etching a thin metal sheet.

  4. Report filing in histopathology.

    PubMed Central

    Blenkinsopp, W K

    1977-01-01

    An assessment of alternative methods of filing histopathology report forms in alphabetical order showed that orthodox card index filing is satisfactory up to about 100000 reports but, because of the need for long-term retrieval, when the reports filed exceed this number they should be copied on jacketed microfilm and a new card index file begun. PMID:591645

  5. Molecular systematics, species delimitation and diversification patterns of the Phyllodactylus lanei complex (Gekkota: Phyllodactylidae) in Mexico.

    PubMed

    Ramírez-Reyes, Tonatiuh; Piñero, Daniel; Flores-Villela, Oscar; Vázquez-Domínguez, Ella

    2017-10-01

    The description of cryptic gecko species worldwide has revealed both that many putative species are, in fact, conformed by a complex of morphologically conserved species that are genetically distinct and highly divergent, and that gecko species diversity could be underestimated. The taxonomy and species delimitation of geckos belonging to the genus Phyllodactylus is still controversial, 16 of which are distributed in Mexico and 13 are endemic. Although the large morphological variation shown by the Phyllodactylus species from Mexico has been amply documented, little is known about their genetic diversity and evolutionary relationships, and much less regarding cryptic speciation. Here, we included the most comprehensive sampling of populations and species of the Phyllodactylus lanei complex distributed in Mexico, and applied an analytical approach that included probabilistic phylogenetic analyses, jointly with species delimitation methods and Bayesian putative species validation analysis. Our results suggest the existence of 10 lineages within the complex, supporting the existence of cryptic species, and in great contrast with the current taxonomic proposal that includes only four subspecies. The most recent common ancestor (MRCA) for the P. lanei clade originated on the Early Eocene (∼54Mya), along the southern coasts of Mexico, followed by the highest diversification of the complex MRCA during the Eocene (34-56Mya). Lineages subsequently dispersed and diversified towards the northwest, and the diversification process ended with the most recent lineages inhabiting two islands on the coasts of Nayarit (Miocene; 5.5-23Mya). Our results highlight three vicariant events associated with the evolution of the lineages, two of them intimately related to the formation of the Sierra Madre del Sur and the Transmexican Volcanic Belt mountain ranges, main geographic barriers that isolated and facilitated the divergence and speciation in this group of geckos. Finally, we

  6. Quantitative Microbial Risk Assessment Tutorial: Publishing a Microbial Density Time Series as a Txt File

    EPA Science Inventory

    A SARA Timeseries Utility supports analysis and management of time-varying environmental data including listing, graphing, computing statistics, computing meteorological data and saving in a WDM or text file. File formats supported include WDM, HSPF Binary (.hbn), USGS RDB, and T...

  7. Securing the AliEn File Catalogue - Enforcing authorization with accountable file operations

    NASA Astrophysics Data System (ADS)

    Schreiner, Steffen; Bagnasco, Stefano; Sankar Banerjee, Subho; Betev, Latchezar; Carminati, Federico; Vladimirovna Datskova, Olga; Furano, Fabrizio; Grigoras, Alina; Grigoras, Costin; Mendez Lorenzo, Patricia; Peters, Andreas Joachim; Saiz, Pablo; Zhu, Jianlin

    2011-12-01

    The AliEn Grid Services, as operated by the ALICE Collaboration in its global physics analysis grid framework, is based on a central File Catalogue together with a distributed set of storage systems and the possibility to register links to external data resources. This paper describes several identified vulnerabilities in the AliEn File Catalogue access protocol regarding fraud and unauthorized file alteration and presents a more secure and revised design: a new mechanism, called LFN Booking Table, is introduced in order to keep track of access authorization in the transient state of files entering or leaving the File Catalogue. Due to a simplification of the original Access Envelope mechanism for xrootd-protocol-based storage systems, fundamental computational improvements of the mechanism were achieved as well as an up to 50% reduction of the credential's size. By extending the access protocol with signed status messages from the underlying storage system, the File Catalogue receives trusted information about a file's size and checksum and the protocol is no longer dependent on client trust. Altogether, the revised design complies with atomic and consistent transactions and allows for accountable, authentic, and traceable file operations. This paper describes these changes as part and beyond the development of AliEn version 2.19.

  8. Bioinformatic Analyses of Subgroup-A Members of the Wheat bZIP Transcription Factor Family and Functional Identification of TabZIP174 Involved in Drought Stress Response

    PubMed Central

    Li, Xueyin; Feng, Biane; Zhang, Fengjie; Tang, Yimiao; Zhang, Liping; Ma, Lingjian; Zhao, Changping; Gao, Shiqing

    2016-01-01

    Extensive studies in Arabidopsis and rice have demonstrated that Subgroup-A members of the bZIP transcription factor family play important roles in plant responses to multiple abiotic stresses. Although common wheat (Triticum aestivum) is one of the most widely cultivated and consumed food crops in the world, there are limited investigations into Subgroup A of the bZIP family in wheat. In this study, we performed bioinformatic analyses of the 41 Subgroup-A members of the wheat bZIP family. Phylogenetic and conserved motif analyses showed that most of the Subgroup-A bZIP proteins involved in abiotic stress responses of wheat, Arabidopsis, and rice clustered in Clade A1 of the phylogenetic tree, and shared a majority of conserved motifs, suggesting the potential importance of Clade-A1 members in abiotic stress responses. Gene structure analysis showed that TabZIP genes with close phylogenetic relationships tended to possess similar exon–intron compositions, and the positions of introns in the hinge regions of the bZIP domains were highly conserved, whereas introns in the leucine zipper regions were at variable positions. Additionally, eleven groups of homologs and two groups of tandem paralogs were also identified in Subgroup A of the wheat bZIP family. Expression profiling analysis indicated that most Subgroup-A TabZIP genes were responsive to abscisic acid and various abiotic stress treatments. TabZIP27, TabZIP74, TabZIP138, and TabZIP174 proteins were localized in the nucleus of wheat protoplasts, whereas TabZIP9-GFP fusion protein was simultaneously present in the nucleus, cytoplasm, and cell membrane. Transgenic Arabidopsis overexpressing TabZIP174 displayed increased seed germination rates and primary root lengths under drought treatments. Overexpression of TabZIP174 in transgenic Arabidopsis conferred enhanced drought tolerance, and transgenic plants exhibited lower water loss rates, higher survival rates, higher proline, soluble sugar, and leaf chlorophyll

  9. 11 CFR 100.19 - File, filed or filing (2 U.S.C. 434(a)).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Time on the filing date, except that pre-election reports must have a postmark dated no later than 11:59 p.m. Eastern Standard/Daylight Time on the fifteenth day before the date of the election. (2... Standard/Daylight Time on the filing date. (d) 48-hour and 24-hour reports of independent expenditures—(1...

  10. DSSTOX MASTER STRUCTURE-INDEX FILE: SDF FILE AND DOCUMENTATION

    EPA Science Inventory

    The DSSTox Master Structure-Index File serves to consolidate, manage, and ensure quality and uniformity of the chemical and substance information spanning all DSSTox Structure Data Files, including those in development but not yet published separately on this website.

  11. County-based estimates of nitrogen and phosphorus content of animal manure in the United States for 1982, 1987, and 1992

    USGS Publications Warehouse

    Puckett, Larry; Hitt, Kerie; Alexander, Richard

    1998-01-01

    names that correspond to the FIPS codes. 2. Tabular component - Nine tab-delimited ASCII lookup tables of animal counts and nutrient estimates organized by 5-digit state/county FIPS (Federal Information Processing Standards) code. Another table lists the county names that correspond to the FIPS codes. The use of trade names is for identification purposes only and does not constitute endorsement by the U.S. Geological Survey.

  12. KAnalyze: a fast versatile pipelined k-mer toolkit.

    PubMed

    Audano, Peter; Vannberg, Fredrik

    2014-07-15

    Converting nucleotide sequences into short overlapping fragments of uniform length, k-mers, is a common step in many bioinformatics applications. While existing software packages count k-mers, few are optimized for speed, offer an application programming interface (API), a graphical interface or contain features that make it extensible and maintainable. We designed KAnalyze to compete with the fastest k-mer counters, to produce reliable output and to support future development efforts through well-architected, documented and testable code. Currently, KAnalyze can output k-mer counts in a sorted tab-delimited file or stream k-mers as they are read. KAnalyze can process large datasets with 2 GB of memory. This project is implemented in Java 7, and the command line interface (CLI) is designed to integrate into pipelines written in any language. As a k-mer counter, KAnalyze outperforms Jellyfish, DSK and a pipeline built on Perl and Linux utilities. Through extensive unit and system testing, we have verified that KAnalyze produces the correct k-mer counts over multiple datasets and k-mer sizes. KAnalyze is available on SourceForge: https://sourceforge.net/projects/kanalyze/. © The Author 2014. Published by Oxford University Press.

  13. E-RNAi: a web application for the multi-species design of RNAi reagents—2010 update

    PubMed Central

    Horn, Thomas; Boutros, Michael

    2010-01-01

    The design of RNA interference (RNAi) reagents is an essential step for performing loss-of-function studies in many experimental systems. The availability of sequenced and annotated genomes greatly facilitates RNAi experiments in an increasing number of organisms that were previously not genetically tractable. The E-RNAi web-service, accessible at http://www.e-rnai.org/, provides a computational resource for the optimized design and evaluation of RNAi reagents. The 2010 update of E-RNAi now covers 12 genomes, including Drosophila, Caenorhabditis elegans, human, emerging model organisms such as Schmidtea mediterranea and Acyrthosiphon pisum, as well as the medically relevant vectors Anopheles gambiae and Aedes aegypti. The web service calculates RNAi reagents based on the input of target sequences, sequence identifiers or by visual selection of target regions through a genome browser interface. It identifies optimized RNAi target-sites by ranking sequences according to their predicted specificity, efficiency and complexity. E-RNAi also facilitates the design of secondary RNAi reagents for validation experiments, evaluation of pooled siRNA reagents and batch design. Results are presented online, as a downloadable HTML report and as tab-delimited files. PMID:20444868

  14. Fail-over file transfer process

    NASA Technical Reports Server (NTRS)

    Semancik, Susan K. (Inventor); Conger, Annette M. (Inventor)

    2005-01-01

    The present invention provides a fail-over file transfer process to handle data file transfer when the transfer is unsuccessful in order to avoid unnecessary network congestion and enhance reliability in an automated data file transfer system. If a file cannot be delivered after attempting to send the file to a receiver up to a preset number of times, and the receiver has indicated the availability of other backup receiving locations, then the file delivery is automatically attempted to one of the backup receiving locations up to the preset number of times. Failure of the file transfer to one of the backup receiving locations results in a failure notification being sent to the receiver, and the receiver may retrieve the file from the location indicated in the failure notification when ready.

  15. Method and apparatus for mounting a dichroic mirror in a microwave powered lamp assembly using deformable tabs

    DOEpatents

    Ury, M.; Sowers, F.; Harper, C.; Love, W.

    1998-11-24

    A microwave powered electrodeless lamp includes an improved screen unit having mesh and solid sections with an internal reflector secured at the juncture of the two sections to reflect light into a light-transmitting chamber defined in the lamp microwave cavity by the reflector and the mesh section. A discharge envelope of a bulb is disposed in the light-transmitting chamber. Light emitted from the envelope is prevented by the reflector from entering the cavity portion bounded by the solid section of the screen. The reflector is mounted in the cavity by tabs formed in the screen unit and bendable into the cavity to define support planes abutting respective surfaces of the reflector. The mesh section and tabs are preferably formed by etching a thin metal sheet. 7 figs.

  16. 33 CFR 148.246 - When is a document considered filed and where should I file it?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... filed and where should I file it? 148.246 Section 148.246 Navigation and Navigable Waters COAST GUARD... Formal Hearings § 148.246 When is a document considered filed and where should I file it? (a) If a document to be filed is submitted by mail, it is considered filed on the date it is postmarked. If a...

  17. Program to convert SUDS2ASC files to a single binary SEGY file

    USGS Publications Warehouse

    Goldman, Mark

    2000-01-01

    This program, SUDS2SEGY, converts and combines ASCII files created using SUDS2ASC Version 2.60, to a single SEGY file. SUDS2ASC has been used previously to create an ASCII file of three-component seismic data for an individual recording station. However, many seismic processing packages have difficulty reading in ASCII data. In addition, it may be cumbersome to process a separate file for each recording station, particularly if traces from different recording stations contain a different number of data samples and/or a different start time. This new program - SUDS2SEGY - combines these recording station files into a single SEGY file. In addition, SUDS2SEGY normalizes the trace times so that each trace starts at a given time and consists of a fixed number of samples. This normalization allows seismic data from many different stations to be read in as a single "data gather". SUDS2SEGY also produces a report summarizing the offset and maximum absolute amplitude for each component in a station file. These data are output separately to an ASCII file and can be subsequently input to a plotting package.

  18. Converting CSV Files to RKSML Files

    NASA Technical Reports Server (NTRS)

    Trebi-Ollennu, Ashitey; Liebersbach, Robert

    2009-01-01

    A computer program converts, into a format suitable for processing on Earth, files of downlinked telemetric data pertaining to the operation of the Instrument Deployment Device (IDD), which is a robot arm on either of the Mars Explorer Rovers (MERs). The raw downlinked data files are in comma-separated- value (CSV) format. The present program converts the files into Rover Kinematics State Markup Language (RKSML), which is an Extensible Markup Language (XML) format that facilitates representation of operations of the IDD and enables analysis of the operations by means of the Rover Sequencing Validation Program (RSVP), which is used to build sequences of commanded operations for the MERs. After conversion by means of the present program, the downlinked data can be processed by RSVP, enabling the MER downlink operations team to play back the actual IDD activity represented by the telemetric data against the planned IDD activity. Thus, the present program enhances the diagnosis of anomalies that manifest themselves as differences between actual and planned IDD activities.

  19. 29 CFR 2200.8 - Filing.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... document shall be filed. (e) Filing date. (1) Except for the documents listed in paragraph (e)(2) of this... 29 Labor 9 2010-07-01 2010-07-01 false Filing. 2200.8 Section 2200.8 Labor Regulations Relating to... § 2200.8 Filing. (a) What to file. All papers required to be served on a party or intervenor, except for...

  20. Cost-effective antigen testing for delimitation, monitoring and evaluation in bancroftian filariasis.

    PubMed

    Das, L K; Pani, S P; Vanamail, P; Vijayalakshmi, G; Debritto, L J

    2012-01-31

    This study was focussed on identifying a cost-effective method for delimitation, monitoring and evaluation in bancroftian filariasis. Finger prick blood samples were collected between 20.00 and 23.00 hours for the detection of microfilariae (mf) from the available population in a village which was endemic for lymphatic filariasis. Simultaneously, from each individual, four spots of 25-μl blood samples were collected on Whatman number 3 filter paper and air dried. Dried filter paper spots were pooled in quantities of 1, 5, 10, 15, 20 and 25 on unknown and simulated mf and antigen prevalence. Pooled samples were assayed for circulating filarial antigen (CFA) using TropBIO Og4C3 ELISA kits. The community mf and CFA rates were 3.4% and 25.9%, respectively. The pool sizes of 20 and 25 showed CFA positivity in all the above categories tested. The results of the pooled blood spot samples suggest that, in areas with mf and CFA prevalence rates between 1 and 10%, pools of 20 or 25 could be considered as the ideal pool size for the detection of filarial infection in the community. CFA prevalence at the level of 5-6% following desirable rounds of mass drug administration (MDA) indicates that the community mf prevalence is likely to be at the 1% level.

  1. 76 FR 43679 - Filing via the Internet; Notice of Additional File Formats for efiling

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-21

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. RM07-16-000] Filing via the Internet; Notice of Additional File Formats for efiling Take notice that the Commission has added to its list of acceptable file formats the four-character file extensions for Microsoft Office 2007/2010...

  2. Resolving species delimitation within the genus Bunopus Blanford, 1874 (Squamata: Gekkonidae) in Iran using DNA barcoding approach.

    PubMed

    Khosravani, Azar; Rastegar-Pouyani, Eskandar; Rastegar-Pouyani, Nasrullah; Oraie, Hamzeh; Papenfuss, Theodore J

    2017-12-19

    Mitochondrial COI sequences were used to investigate species delimitation within the genus Bunopus in Iran. A dataset with a final sequence length of 633 nucleotides including 100 specimens from 31 geographically distant localities across Iran were generated. The result demonstrated that two major clades with strong support can be identified within the genus Bunopus in Iran. Clade A includes Bunopus crassicaudus and two new entities, eastern populations (subclade A2,1) and Shahdad populations (subclade A2,2). The second clade comprises western and southwestern populations (subclade B1,1), Arabian populations (subclade B1,2) and south and southeast populations in Iran, to which Bunopus tuberculatus (subclade B2) is assigned. In addition to Bunopus crassicaudus and B. tuberculatus, three new candidate species in Iran can easily be identified based on the DNA barcoding approach.

  3. Zebra: A striped network file system

    NASA Technical Reports Server (NTRS)

    Hartman, John H.; Ousterhout, John K.

    1992-01-01

    The design of Zebra, a striped network file system, is presented. Zebra applies ideas from log-structured file system (LFS) and RAID research to network file systems, resulting in a network file system that has scalable performance, uses its servers efficiently even when its applications are using small files, and provides high availability. Zebra stripes file data across multiple servers, so that the file transfer rate is not limited by the performance of a single server. High availability is achieved by maintaining parity information for the file system. If a server fails its contents can be reconstructed using the contents of the remaining servers and the parity information. Zebra differs from existing striped file systems in the way it stripes file data: Zebra does not stripe on a per-file basis; instead it stripes the stream of bytes written by each client. Clients write to the servers in units called stripe fragments, which are analogous to segments in an LFS. Stripe fragments contain file blocks that were written recently, without regard to which file they belong. This method of striping has numerous advantages over per-file striping, including increased server efficiency, efficient parity computation, and elimination of parity update.

  4. Permanent-File-Validation Utility Computer Program

    NASA Technical Reports Server (NTRS)

    Derry, Stephen D.

    1988-01-01

    Errors in files detected and corrected during operation. Permanent File Validation (PFVAL) utility computer program provides CDC CYBER NOS sites with mechanism to verify integrity of permanent file base. Locates and identifies permanent file errors in Mass Storage Table (MST) and Track Reservation Table (TRT), in permanent file catalog entries (PFC's) in permit sectors, and in disk sector linkage. All detected errors written to listing file and system and job day files. Program operates by reading system tables , catalog track, permit sectors, and disk linkage bytes to vaidate expected and actual file linkages. Used extensively to identify and locate errors in permanent files and enable online correction, reducing computer-system downtime.

  5. The geochemical landscape of northwestern Wisconsin and adjacent parts of northern Michigan and Minnesota (geochemical data files)

    USGS Publications Warehouse

    Cannon, William F.; Woodruff, Laurel G.

    2003-01-01

    This data set consists of nine files of geochemical information on various types of surficial deposits in northwestern Wisconsin and immediately adjacent parts of Michigan and Minnesota. The files are presented in two formats: as dbase files in dbaseIV form and Microsoft Excel form. The data present multi-element chemical analyses of soils, stream sediments, and lake sediments. Latitude and longitude values are provided in each file so that the dbf files can be readily imported to GIS applications. Metadata files are provided in outline form, question and answer form and text form. The metadata includes information on procedures for sample collection, sample preparation, and chemical analyses including sensitivity and precision.

  6. 77 FR 71587 - Wisconsin Public Service Corporation; Notices of Intent To File License Applications, Filing of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-03

    ...] Wisconsin Public Service Corporation; Notices of Intent To File License Applications, Filing of Pre-Application Documents (PAD), Commencement of Pre-Filing Processes and Scoping, Request for Comments on the...: Notices of Intent to File License Applications for Two New Licenses and Commencing the Pre-filing Process...

  7. Phylogenomics and species delimitation of a complex radiation of Neotropical suboscine birds (Pachyramphus).

    PubMed

    Musher, Lukas J; Cracraft, Joel

    2018-01-01

    Phylogeographic studies within the Neotropics continue to uncover hidden diversity, the extent of which remains poorly known. In birds, molecular studies are producing evidence that species-level diversity is substantially underestimated. Many avian taxa comprise large complexes of subspecies that often represent species-level taxa by various criteria. One such group of Neotropical suboscine birds, the becards (Pachyramphus), ranges from Argentina through northern Mexico. Their taxonomic limits have been complex and controversial as the genus has bounced around a number of suboscine families. Additionally, the phylogenetic relationships within Pachyramphus are unresolved due to insufficient sampling of taxa and populations across species' ranges. We used target capture of ultraconserved elements for 62 individuals representing 42 taxa, and sequenced two mitochondrial genes and two nuclear introns covering 265 individuals of 51 taxa, including all recognized species, resulting in the most densely and completely sampled phylogenetic hypothesis for Pachyramphus to date. We delimited species using a traditional taxonomic approach and then tested them under a Bayesian multi-species coalescent framework. In doing so, we provide evidence for multiple young, previously undetected evolutionary lineages within Pachyramphus. Deep, well-supported branches and a high number of intraspecific lineages across the tree suggest that at least 50% of species diversity may be unrecognized. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Reliable Electronic Text: The Elusive Prerequisite for a Host of Human Language Technologies

    DTIC Science & Technology

    2010-09-30

    is not always the case—for example, ligatures in Latin-fonts, and glyphs in Arabic fonts (King, 2008; Carrier, 2009). This complexity, and others...such effects can render electronic text useless for natural language processing ( NLP ). Typically, file converters do not expose the details of the...the many component NLP technologies typically used inside information extraction and text categorization applications, such as tokenization, part-of

  9. Morphology delimits more species than molecular genetic clusters of invasive Pilosella.

    PubMed

    Moffat, Chandra E; Ensing, David J; Gaskin, John F; De Clerck-Floate, Rosemarie A; Pither, Jason

    2015-07-01

    • Accurate assessments of biodiversity are paramount for understanding ecosystem processes and adaptation to change. Invasive species often contribute substantially to local biodiversity; correctly identifying and distinguishing invaders is thus necessary to assess their potential impacts. We compared the reliability of morphology and molecular sequences to discriminate six putative species of invasive Pilosella hawkweeds (syn. Hieracium, Asteraceae), known for unreliable identifications and historical introgression. We asked (1) which morphological traits dependably discriminate putative species, (2) if genetic clusters supported morphological species, and (3) if novel hybridizations occur in the invaded range.• We assessed 33 morphometric characters for their discriminatory power using the randomForest classifier and, using AFLPs, evaluated genetic clustering with the program structure and subsequently with an AMOVA. The strength of the association between morphological and genotypic dissimilarity was assessed with a Mantel test.• Morphometric analyses delimited six species while genetic analyses defined only four clusters. Specifically, we found (1) eight morphological traits could reliably distinguish species, (2) structure suggested strong genetic differentiation but for only four putative species clusters, and (3) genetic data suggest both novel hybridizations and multiple introductions have occurred.• (1) Traditional floristic techniques may resolve more species than molecular analyses in taxonomic groups subject to introgression. (2) Even within complexes of closely related species, relatively few but highly discerning morphological characters can reliably discriminate species. (3) By clarifying patterns of morphological and genotypic variation of invasive Pilosella, we lay foundations for further ecological study and mitigation. © 2015 Botanical Society of America, Inc.

  10. GEWEX-RFA Data File Format and File Naming Convention

    Atmospheric Science Data Center

    2016-05-20

    ... documentation, will be stored for each data product. Each time data is added to, removed from, or modified in the file set for a product, ... including 29 days in leap-year Februaries. Time series files containing 15-minute data should start at the top of an hour to ...

  11. Species delimitation in the Stenocereus griseus (Cactaceae) species complex reveals a new species, S. huastecorum

    PubMed Central

    Alvarado-Sizzo, Hernán; Parra, Fabiola; Arreola-Nava, Hilda Julieta; Terrazas, Teresa; Sánchez, Cristian

    2018-01-01

    The Stenocereus griseus species complex (SGSC) has long been considered taxonomically challenging because the number of taxa belonging to the complex and their geographical boundaries remain poorly understood. Bayesian clustering and genetic distance-based methods were used based on nine microsatellite loci in 377 individuals of three main putative species of the complex. The resulting genetic clusters were assessed for ecological niche divergence and areolar morphology, particularly spination patterns. We based our species boundaries on concordance between genetic, ecological, and morphological data, and were able to resolve four species, three of them corresponding to S. pruinosus from central Mexico, S. laevigatus from southern Mexico, and S. griseus from northern South America. A fourth species, previously considered to be S. griseus and commonly misidentified as S. pruinosus in northern Mexico showed significant genetic, ecological, and morphological differentiation suggesting that it should be considered a new species, S. huastecorum, which we describe here. We show that population genetic analyses, ecological niche modeling, and morphological studies are complementary approaches for delimiting species in taxonomically challenging plant groups such as the SGSC. PMID:29342184

  12. Species delimitation in the Stenocereus griseus (Cactaceae) species complex reveals a new species, S. huastecorum.

    PubMed

    Alvarado-Sizzo, Hernán; Casas, Alejandro; Parra, Fabiola; Arreola-Nava, Hilda Julieta; Terrazas, Teresa; Sánchez, Cristian

    2018-01-01

    The Stenocereus griseus species complex (SGSC) has long been considered taxonomically challenging because the number of taxa belonging to the complex and their geographical boundaries remain poorly understood. Bayesian clustering and genetic distance-based methods were used based on nine microsatellite loci in 377 individuals of three main putative species of the complex. The resulting genetic clusters were assessed for ecological niche divergence and areolar morphology, particularly spination patterns. We based our species boundaries on concordance between genetic, ecological, and morphological data, and were able to resolve four species, three of them corresponding to S. pruinosus from central Mexico, S. laevigatus from southern Mexico, and S. griseus from northern South America. A fourth species, previously considered to be S. griseus and commonly misidentified as S. pruinosus in northern Mexico showed significant genetic, ecological, and morphological differentiation suggesting that it should be considered a new species, S. huastecorum, which we describe here. We show that population genetic analyses, ecological niche modeling, and morphological studies are complementary approaches for delimiting species in taxonomically challenging plant groups such as the SGSC.

  13. A File Archival System

    NASA Technical Reports Server (NTRS)

    Fanselow, J. L.; Vavrus, J. L.

    1984-01-01

    ARCH, file archival system for DEC VAX, provides for easy offline storage and retrieval of arbitrary files on DEC VAX system. System designed to eliminate situations that tie up disk space and lead to confusion when different programers develop different versions of same programs and associated files.

  14. Demographic Profile of U.S. Children: National File [Machine-Readable Data File].

    ERIC Educational Resources Information Center

    Peterson, J. L.; White, R. N.

    These two computer files contain social and demographic data about U.S. children and their families taken from the March 1985 Current Population Survey of the U.S. Census. One file is for all children; the second file is for black children. The following column variables are included: (1) family structure; (2) parent educational attainment; (3)…

  15. Lower Rehospitalization Rates among Rural Medicare Beneficiaries with Diabetes

    ERIC Educational Resources Information Center

    Bennett, Kevin J.; Probst, Janice C.; Vyavaharkar, Medha; Glover, Saundra H.

    2012-01-01

    Purpose: We estimated the 30-day readmission rate of Medicare beneficiaries with diabetes, across levels of rurality. Methods: We merged the 2005 Medicare Chronic Conditions 5% sample data with the 2007 Area Resource File. The study population was delimited to those with diabetes and at least 1 hospitalization in the year. Unadjusted readmission…

  16. 78 FR 17233 - Notice of Opportunity To File Amicus Briefs

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-20

    .... Any commonly-used word processing format or PDF format is acceptable; text formats are preferable to image formats. Briefs may also be filed with the Office of the Clerk of the Board, Merit Systems...

  17. Converting Inhouse Subject Card Files to Electronic Keyword Files.

    ERIC Educational Resources Information Center

    Culmer, Carita M.

    The library at Phoenix College developed the Controversial Issues Files (CIF), a "home made" card file containing references pertinent to specific ongoing assignments. Although the CIF had proven itself to be an excellent resource tool for beginning researchers, it was cumbersome to maintain in the card format, and was limited to very…

  18. Phylogenetic relationship and species delimitation of matsutake and allied species based on multilocus phylogeny and haplotype analyses.

    PubMed

    Ota, Yuko; Yamanaka, Takashi; Murata, Hitoshi; Neda, Hitoshi; Ohta, Akira; Kawai, Masataka; Yamada, Akiyoshi; Konno, Miki; Tanaka, Chihiro

    2012-01-01

    Tricholoma matsutake (S. Ito & S. Imai) Singer and its allied species are referred to as matsutake worldwide and are the most economically important edible mushrooms in Japan. They are widely distributed in the northern hemisphere and established an ectomycorrhizal relationship with conifer and broadleaf trees. To clarify relationships among T. matsutake and its allies, and to delimit phylogenetic species, we analyzed multilocus datasets (ITS, megB1, tef, gpd) with samples that were correctly identified based on morphological characteristics. Phylogenetic analyses clearly identified four major groups: matsutake, T. bakamatsutake, T. fulvocastaneum and T. caligatum; the latter three species were outside the matsutake group. The haplotype analyses and median-joining haplotype network analyses showed that the matsutake group included four closely related but clearly distinct taxa (T. matsutake, T. anatolicum, Tricholoma sp. from Mexico and T. magnivelare) from different geographical regions; these were considered to be distinct phylogenetic species.

  19. 78 FR 64883 - Filing Financial and Other Reports

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-30

    ... paragraph (a) introductory text to read as follows: Sec. 741.6 Financial and statistical and other reports..., statistical, and other reports and credit union profiles by requiring all federally insured credit unions.... Section 741.6(a) of NCUA's regulations requires FICUs to file financial, statistical, and other reports...

  20. Interoperability format translation and transformation between IFC architectural design file and simulation file formats

    DOEpatents

    Chao, Tian-Jy; Kim, Younghun

    2015-02-03

    Automatically translating a building architecture file format (Industry Foundation Class) to a simulation file, in one aspect, may extract data and metadata used by a target simulation tool from a building architecture file. Interoperability data objects may be created and the extracted data is stored in the interoperability data objects. A model translation procedure may be prepared to identify a mapping from a Model View Definition to a translation and transformation function. The extracted data may be transformed using the data stored in the interoperability data objects, an input Model View Definition template, and the translation and transformation function to convert the extracted data to correct geometric values needed for a target simulation file format used by the target simulation tool. The simulation file in the target simulation file format may be generated.

  1. Torsional and cyclic fatigue resistances of glide path preparation instruments: G-file and PathFile.

    PubMed

    Sung, Sang Yup; Ha, Jung-Hong; Kwak, Sang-Won; Abed, Rashid El; Byeon, Kyeongmin; Kim, Hyeon-Cheol

    2014-01-01

    This study aimed to compare cyclic fatigue and torsional resistances of glide path creating instruments with different tapers and tip sizes. Two sizes (G1 and G2) from G-File system and three sizes (PathFile #1, #2, and #3) from PathFile system were used for torsional resistance and cyclic fatigue resistance tests (n = 10). The torsional resistance was evaluated at 2-, 3-, 4-, 5-, and 6-mm from the file tip by plotting the torsional load changes until fracture by rotational loading of 2 rpm. The cyclic fatigue resistance was compared by measuring the number of cycles to failure. Data were analyzed statistically using one-way ANOVA and Duncan's post-hoc comparison. The length of the fractured file fragment was also measured. All fractured fragments were observed under a scanning electron microscope (SEM). Although G-2 file showed a lower torsional strength than PathFile #3 at 2- and 3-mm levels (p < 0.05), they had similar ultimate strengths at 4-, 5-, and 6-mm levels (p > 0.05). The smaller files of each brand had a significantly higher cyclic fatigue resistance than the bigger ones (p < 0.05). PathFile #1 and #2 had higher fatigue resistances than G-files (p < 0.05). While G-1 had a similar fatigue resistance as PathFile #3, G-2 showed the lowest and PathFile #1 showed the highest resistances among the tested groups (p < 0.05). The SEM examination showed typical appearances of cyclic fatigue and torsional fractures, regardless of the tested levels. Clinicians may consider the instruments' sizes for each clinical case in order to get efficient glide path with minimal risk of fracture. © 2014 Wiley Periodicals, Inc.

  2. Apically extruded dentin debris by reciprocating single-file and multi-file rotary system.

    PubMed

    De-Deus, Gustavo; Neves, Aline; Silva, Emmanuel João; Mendonça, Thais Accorsi; Lourenço, Caroline; Calixto, Camila; Lima, Edson Jorge Moreira

    2015-03-01

    This study aims to evaluate the apical extrusion of debris by the two reciprocating single-file systems: WaveOne and Reciproc. Conventional multi-file rotary system was used as a reference for comparison. The hypotheses tested were (i) the reciprocating single-file systems extrude more than conventional multi-file rotary system and (ii) the reciprocating single-file systems extrude similar amounts of dentin debris. After solid selection criteria, 80 mesial roots of lower molars were included in the present study. The use of four different instrumentation techniques resulted in four groups (n = 20): G1 (hand-file technique), G2 (ProTaper), G3 (WaveOne), and G4 (Reciproc). The apparatus used to evaluate the collection of apically extruded debris was typical double-chamber collector. Statistical analysis was performed for multiple comparisons. No significant difference was found in the amount of the debris extruded between the two reciprocating systems. In contrast, conventional multi-file rotary system group extruded significantly more debris than both reciprocating groups. Hand instrumentation group extruded significantly more debris than all other groups. The present results yielded favorable input for both reciprocation single-file systems, inasmuch as they showed an improved control of apically extruded debris. Apical extrusion of debris has been studied extensively because of its clinical relevance, particularly since it may cause flare-ups, originated by the introduction of bacteria, pulpal tissue, and irrigating solutions into the periapical tissues.

  3. Development of an indexed integrated neuroradiology reports for teaching file creation

    NASA Astrophysics Data System (ADS)

    Tameem, Hussain Z.; Morioka, Craig; Bennett, David; El-Saden, Suzie; Sinha, Usha; Taira, Ricky; Bui, Alex; Kangarloo, Hooshang

    2007-03-01

    The decrease in reimbursement rates for radiology procedures has placed even more pressure on radiology departments to increase their clinical productivity. Clinical faculties have less time for teaching residents, but with the advent and prevalence of an electronic environment that includes PACS, RIS, and HIS, there is an opportunity to create electronic teaching files for fellows, residents, and medical students. Experienced clinicians, who select the most appropriate radiographic image, and clinical information relevant to that patient, create these teaching files. Important cases are selected based on the difficulty in determining the diagnosis or the manifestation of rare diseases. This manual process of teaching file creation is time consuming and may not be practical under the pressure of increased demands on the radiologist. It is the goal of this research to automate the process of teaching file creation by manually selecting key images and automatically extracting key sections from clinical reports and laboratories. The text report is then processed for indexing to two standard nomenclatures UMLS and RADLEX. Interesting teaching files can then be queried based on specific anatomy and findings found within the clinical reports.

  4. 76 FR 52323 - Combined Notice of Filings; Filings Instituting Proceedings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-22

    .... Applicants: Young Gas Storage Company, Ltd. Description: Young Gas Storage Company, Ltd. submits tariff..., but intervention is necessary to become a party to the proceeding. The filings are accessible in the.... More detailed information relating to filing requirements, interventions, protests, and service can be...

  5. Interoperability format translation and transformation between IFC architectural design file and simulation file formats

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chao, Tian-Jy; Kim, Younghun

    Automatically translating a building architecture file format (Industry Foundation Class) to a simulation file, in one aspect, may extract data and metadata used by a target simulation tool from a building architecture file. Interoperability data objects may be created and the extracted data is stored in the interoperability data objects. A model translation procedure may be prepared to identify a mapping from a Model View Definition to a translation and transformation function. The extracted data may be transformed using the data stored in the interoperability data objects, an input Model View Definition template, and the translation and transformation function tomore » convert the extracted data to correct geometric values needed for a target simulation file format used by the target simulation tool. The simulation file in the target simulation file format may be generated.« less

  6. NASA Uniform Files Index

    NASA Technical Reports Server (NTRS)

    1987-01-01

    This handbook is a guide for the use of all personnel engaged in handling NASA files. It is issued in accordance with the regulations of the National Archives and Records Administration, in the Code of Federal Regulations Title 36, Part 1224, Files Management; and the Federal Information Resources Management Regulation, Subpart 201-45.108, Files Management. It is intended to provide a standardized classification and filing scheme to achieve maximum uniformity and ease in maintaining and using agency records. It is a framework for consistent organization of information in an arrangement that will be useful to current and future researchers. The NASA Uniform Files Index coding structure is composed of the subject classification table used for NASA management directives and the subject groups in the NASA scientific and technical information system. It is designed to correlate files throughout NASA and it is anticipated that it may be useful with automated filing systems. It is expected that in the conversion of current files to this arrangement it will be necessary to add tertiary subjects and make further subdivisions under the existing categories. Established primary and secondary subject categories may not be changed arbitrarily. Proposals for additional subject categories of NASA-wide applicability, and suggestions for improvement in this handbook, should be addressed to the Records Program Manager at the pertinent installation who will forward it to the NASA Records Management Office, Code NTR, for approval. This handbook is issued in loose-leaf form and will be revised by page changes.

  7. 20 CFR 217.16 - Filing date.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Filing date. 217.16 Section 217.16 Employees... LUMP SUM Filing An Application § 217.16 Filing date. An application filed in a manner and form acceptable to the Board is officially filed with the Board on the earliest of the following dates: (a) On the...

  8. Sensitivity Data File Formats

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rearden, Bradley T.

    2016-04-01

    The format of the TSUNAMI-A sensitivity data file produced by SAMS for cases with deterministic transport solutions is given in Table 6.3.A.1. The occurrence of each entry in the data file is followed by an identification of the data contained on each line of the file and the FORTRAN edit descriptor denoting the format of each line. A brief description of each line is also presented. A sample of the TSUNAMI-A data file for the Flattop-25 sample problem is provided in Figure 6.3.A.1. Here, only two profiles out of the 130 computed are shown.

  9. 75 FR 38805 - Filing Via the Internet; Electronic Tariff Filings Notice of Display of Time on Commission's...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-06

    ... system the time used by the Commission to mark officially the time that eFilings and eTariff submissions... timely. The time display will assist users in ensuring that their filings are timely filed, i.e., are... electronic submissions in lieu of paper using the eFiling link at http://www.ferc.gov . Also, Filing...

  10. Cyclic fatigue resistance of a novel rotary file manufactured using controlled memory Ni-Ti technology compared to a file made from M-wire file.

    PubMed

    AlShwaimi, E

    2018-01-01

    To compare the cyclic fatigue properties of a novel file made using controlled memory Ni-Ti technology with those of files made from M-wire. Twelve files with similar cross-sectional geometry and tip size from each of the following groups were tested: Proflexendo made from CMT (PE; size 30 0.04; Nexden, Houston, Tx, USA), ProFile Vortex made from M-wire (PV; size 30 0.04; Dentsply Tulsa Dental, Tulsa, OK, USA) and ProTaper Universal made from regular alloy (PU; F3; Dentsply Tulsa Dental). A custom-made cyclic fatigue device was made to evaluate the total number of cycles to failure for each system. A scanning electron microscope (SEM) was used to examine the fractured surfaces of the fragments. The arithmetic means and standard deviations were calculated for the total number of cycles to failure. One-way analysis of variance was used to compare the mean cyclic failure amongst the three groups. Post hoc Tukey's test was performed to compare the difference of the means between the groups at a significance level of P < 0.05. Proflexendo had a significantly greater resistance to cyclic fatigue compared to other systems (P < 0.001). Proflexendo files were able to withstand 500% more cycles to fracture when compared to ProFile Vortex files. Manufacturing technique had a significant impact on the resistance to cyclic fatigue. Proflexendo files made from controlled memory Ni-Ti technology had the highest number of cycles to failure compared to ProFile Vortex made from M-wire files with similar taper and tip size. © 2017 International Endodontic Journal. Published by John Wiley & Sons Ltd.

  11. Usage analysis of user files in UNIX

    NASA Technical Reports Server (NTRS)

    Devarakonda, Murthy V.; Iyer, Ravishankar K.

    1987-01-01

    Presented is a user-oriented analysis of short term file usage in a 4.2 BSD UNIX environment. The key aspect of this analysis is a characterization of users and files, which is a departure from the traditional approach of analyzing file references. Two characterization measures are employed: accesses-per-byte (combining fraction of a file referenced and number of references) and file size. This new approach is shown to distinguish differences in files as well as users, which cam be used in efficient file system design, and in creating realistic test workloads for simulations. A multi-stage gamma distribution is shown to closely model the file usage measures. Even though overall file sharing is small, some files belonging to a bulletin board system are accessed by many users, simultaneously and otherwise. Over 50% of users referenced files owned by other users, and over 80% of all files were involved in such references. Based on the differences in files and users, suggestions to improve the system performance were also made.

  12. 78 FR 6772 - Failure To File Gain Recognition Agreements and Other Required Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-31

    ... regulations that would amend the existing rules governing the consequences to U.S. persons for failing to file... current law, if a U.S. transferor fails to timely file an initial GRA, or fails to comply in any material... fails to timely file an annual certification), the U.S. transferor is subject to full gain recognition...

  13. Population delimitation across contrasting evolutionary clines in deer mice (Peromyscus maniculatus)

    PubMed Central

    Yang, D-S; Kenagy, G

    2011-01-01

    Despite current interest in population genetics, a concrete definition of a “population” remains elusive. Multiple ecologically and evolutionarily based definitions of population are in current use, which focus, respectively, on demographic and genetic interactions. Accurate population delimitation is crucial for not only evolutionary and ecological population biology, but also for conservation of threatened populations. Along the Pacific Coast of North America, two contrasting patterns of geographic variation in deer mice (Peromyscus maniculatus) converge within the state of Oregon. Populations of these mice diverge morphologically across an east–west axis, and they diverge in mitochondrial DNA haplotypes across a north–south axis. In this study, we investigate these geographically contrasting patterns of differentiation in the context of ecological and evolutionary definitions (paradigms) of populations. We investigate these patterns using a new and geographically expansive sample that integrates data on morphology, mitochondrial DNA, and nuclear DNA. We found no evidence of nuclear genetic differentiation between the morphologically and mitochondrially distinct populations, thus indicating the occurrence of gene flow across Oregon. Under the evolutionary paradigm, Oregon populations can be considered a single population, whereas morphological and mitochondrial differentiations do not indicate distinct populations. In contrast, under the ecological paradigm morphological differentiation indicates distinct populations based on the low likelihood of demographic interactions between geographically distant individuals. The two sympatric but mitochondrially distinct haplogroups form a single population under the ecological paradigm. Hence, we find that the difference between evolutionary and ecological paradigms is the time-scale of interest, and we believe that the more chronologically inclusive evolutionary paradigm may be preferable except in cases where

  14. Overexpression of a wheat (Triticum aestivum L.) bZIP transcription factor gene, TabZIP6, decreased the freezing tolerance of transgenic Arabidopsis seedlings by down-regulating the expression of CBFs.

    PubMed

    Cai, Wangting; Yang, Yaling; Wang, Weiwei; Guo, Guangyan; Liu, Wei; Bi, Caili

    2018-03-01

    The basic leucine zipper (bZIP) proteins play important roles against abiotic stress in plants, including cold stress. However, most bZIPs involved in plant freezing tolerance are positive regulators. Only a few bZIPs function negatively in cold stress response. In this study, TabZIP6, a Group C bZIP transcription factor gene from common wheat (Triticum aestivum L.), was cloned and characterized. The transcript of TabZIP6 was strongly induced by cold treatment (4 °C). TabZIP6 is a nuclear-localized protein with transcriptional activation activity. Arabidopsis plants overexpressing TabZIP6 showed decreased tolerance to freezing stress. Microarray as well as quantitative real-time PCR (qRT-PCR) analysis showed that CBFs and some key COR genes, including COR47 and COR15B, were down-regulated by cold treatment in TabZIP6-overexpressing Arabidopsis lines. TabZIP6 was capable of binding to the G-box motif and the CBF1 and CBF3 promoters in yeast cells. A yeast two-hybrid assay revealed that TabZIP6, as well as the other two Group S bZIP proteins involved in cold stress tolerance in wheat, Wlip19 and TaOBF1, can form homodimers by themselves and heterodimers with each other. These results suggest that TabZIP6 may function negatively in the cold stress response by binding to the promoters of CBFs, and thereby decreasing the expression of downstream COR genes in TabZIP6-overexpressing Arabidopsis seedlings. Copyright © 2018. Published by Elsevier Masson SAS.

  15. 22 CFR 123.22 - Filing, retention, and return of export licenses and filing of export information.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Filing, retention, and return of export licenses and filing of export information. 123.22 Section 123.22 Foreign Relations DEPARTMENT OF STATE....22 Filing, retention, and return of export licenses and filing of export information. (a) Any export...

  16. 48 CFR 6101.2 - Filing cases; time limits for filing; notice of docketing; consolidation [Rule 2].

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 7 2012-10-01 2012-10-01 false Filing cases; time limits... 6101.2 Filing cases; time limits for filing; notice of docketing; consolidation [Rule 2]. (a) Filing... name, address, telephone number, facsimile machine number, and e-mail address, if available, of the...

  17. Species delimitation in frogs from South American temperate forests: The case of Eupsophus, a taxonomically complex genus with high phenotypic variation

    PubMed Central

    Correa, Claudio; Vásquez, Dayana; Castro-Carrasco, Camila; Zúñiga-Reinoso, Álvaro; Ortiz, Juan Carlos; Palma, R. Eduardo

    2017-01-01

    One of the most characteristic and abundant amphibian taxa of South American temperate forests is Eupsophus. The ten currently recognized species of the genus have been divided in two species groups, roseus and vertebralis, but most of them, eight, belong to the roseus group. Recent phylogeographic and phylogenetic studies have suggested that species diversity of the roseus group could be underestimated. An examination of the literature shows that species of the roseus group exhibit high levels of variation in their external characteristics, particularly those used as diagnostic characters, which compromises their taxonomy and hinders their field recognition. High levels of variation were also observed in several new populations of the roseus group discovered in southern Chile (36°-40°S), which could not be identified to the species level by their external characteristics. On the other hand, the literature reveals a scarse karyotype differentiation and a high bioacoustic uniformity among the species of the roseus group. We performed a Bayesian phylogenetic analysis using mitochondrial and nuclear genes to reevaluate the species diversity of the roseus group, including all the nominal species of Eupsophus and new populations. This analysis was complemented with three species delimitation approaches, General Mixed Yule Coalescent, multi-rate Poisson Tree Process and Automatic Barcode Gap Discovery. We favored a conservative delimitation of only four species for the roseus group, a result more consistent with the distribution of pairwise genetic distances, and the available chromosome and bioacoustic evidence. The four recognized lineages, which have nearly completely allopatric distributions, are named after the earliest nominal species that they include, but because high levels of phenotypic variation, they are not diagnosable by consistent differences in external morphology. We discuss the implications of this new proposal for the taxonomy and conservation of the

  18. RevManHAL: towards automatic text generation in systematic reviews.

    PubMed

    Torres Torres, Mercedes; Adams, Clive E

    2017-02-09

    Systematic reviews are a key part of healthcare evaluation. They involve important painstaking but repetitive work. A major producer of systematic reviews, the Cochrane Collaboration, employs Review Manager (RevMan) programme-a software which assists reviewers and produces XML-structured files. This paper describes an add-on programme (RevManHAL) which helps auto-generate the abstract, results and discussion sections of RevMan-generated reviews in multiple languages. The paper also describes future developments for RevManHAL. RevManHAL was created in Java using NetBeans by a programmer working full time for 2 months. The resulting open-source programme uses editable phrase banks to envelop text/numbers from within the prepared RevMan file in formatted readable text of a chosen language. In this way, considerable parts of the review's 'abstract', 'results' and 'discussion' sections are created and a phrase added to 'acknowledgements'. RevManHAL's output needs to be checked by reviewers, but already, from our experience within the Cochrane Schizophrenia Group (200 maintained reviews, 900 reviewers), RevManHAL has saved much time which is better employed thinking about the meaning of the data rather than restating them. Many more functions will become possible as review writing becomes increasingly automated.

  19. Transparency in Distributed File Systems

    DTIC Science & Technology

    1989-01-01

    ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELEMENT. PROJECT, TASK Computer Science Department AREA & WORK UNIT NUMBERS 734 Comouter Studies Bldc . University of...sistency control , file and director) placement, and file and directory migration in a way that pro- 3 vides full network transparency. This transparency...areas of naming, replication, con- sistency control , file and directory placement, and file and directory migration in a way that pro- 3 vides full

  20. Automatic theory generation from analyst text files using coherence networks

    NASA Astrophysics Data System (ADS)

    Shaffer, Steven C.

    2014-05-01

    This paper describes a three-phase process of extracting knowledge from analyst textual reports. Phase 1 involves performing natural language processing on the source text to extract subject-predicate-object triples. In phase 2, these triples are then fed into a coherence network analysis process, using a genetic algorithm optimization. Finally, the highest-value sub networks are processed into a semantic network graph for display. Initial work on a well- known data set (a Wikipedia article on Abraham Lincoln) has shown excellent results without any specific tuning. Next, we ran the process on the SYNthetic Counter-INsurgency (SYNCOIN) data set, developed at Penn State, yielding interesting and potentially useful results.

  1. 76 FR 39960 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing and Immediate Effectiveness of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-07

    ...-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule... Exchange Act of 1934, as amended (the ``Act''). Upon effectiveness of a plan filed pursuant to Rule 17d-2...(a) through 9.25, which concern advertising and sales literature, would be deleted and the text of...

  2. Cleaning of endodontic files, Part I: The effect of bioburden on the sterilization of endodontic files.

    PubMed

    Johnson, M A; Primack, P D; Loushine, R J; Craft, D W

    1997-01-01

    Ninety-two new endodontic files were randomly assigned to five groups with varying parameters of contamination, cleaning method, and sterilization (steam or chemical). Files were instrumented in bovine teeth to accumulate debris and a known contaminant, Bacillus stearothermophilus. Positive controls produced growth on both T-soy agar plates and in T-soy broth. Negative controls and experimental files (some with heavy debris) failed to produce growth. The results showed that there was no significant difference between contaminated files that were not cleaned before sterilization and contaminated files that were cleaned before sterilization. Bioburden present on endodontic files does not appear to affect the sterilization process.

  3. Exploring the utility of DNA barcoding in species delimitation of Polypedilum (Tripodura) non-biting midges (Diptera: Chironomidae).

    PubMed

    Song, Chao; Wang, Qian; Zhang, Ruilei; Sun, Bingjiao; Wang, Xinhua

    2016-02-16

    In this study, we tested the utility of the mitochondrial gene cytochrome c oxidase subunit 1 (CO1) as the barcode region to deal with taxonomical problems of Polypedilum (Tripodura) non-biting midges (Diptera: Chironomidae). The 114 DNA barcodes representing 27 morphospecies are divided into 33 well separated clusters based on both Neighbor Joining and Maximum Likelihood methods. DNA barcodes revealed an 82% success rate in matching with morphospecies. The selected DNA barcode data support 37-64 operational taxonomic units (OTUs) based on the methods of Automatic Barcode Gap Discovery (ABGD) and Poisson Tree Process (PTP). Furthermore, a priori species based on consistent phenotypic variations were attested by molecular analysis, and a taxonomical misidentification of barcode sequences from GenBank was found. We could not observe a distinct barcode gap but an overlap ranged from 9-12%. Our results supported DNA barcoding as an ideal method to detect cryptic species, delimit sibling species, and associate different life stages in non-biting midges.

  4. The Galley Parallel File System

    NASA Technical Reports Server (NTRS)

    Nieuwejaar, Nils; Kotz, David

    1996-01-01

    As the I/O needs of parallel scientific applications increase, file systems for multiprocessors are being designed to provide applications with parallel access to multiple disks. Many parallel file systems present applications with a conventional Unix-like interface that allows the application to access multiple disks transparently. The interface conceals the parallelism within the file system, which increases the ease of programmability, but makes it difficult or impossible for sophisticated programmers and libraries to use knowledge about their I/O needs to exploit that parallelism. Furthermore, most current parallel file systems are optimized for a different workload than they are being asked to support. We introduce Galley, a new parallel file system that is intended to efficiently support realistic parallel workloads. We discuss Galley's file structure and application interface, as well as an application that has been implemented using that interface.

  5. 77 FR 66601 - Electronic Tariff Filings; Notice of Change to eTariff Type of Filing Codes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-06

    ... Tariff Filings; Notice of Change to eTariff Type of Filing Codes Take notice that, effective November 18, 2012, the list of available eTariff Type of Filing Codes (TOFC) will be modified to include a new TOFC... Energy's regulations. Tariff records included in such filings will be automatically accepted to be...

  6. 76 FR 62092 - Filing Procedures

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-06

    ... INTERNATIONAL TRADE COMMISSION Filing Procedures AGENCY: International Trade Commission. ACTION: Notice of issuance of Handbook on Filing Procedures. SUMMARY: The United States International Trade Commission (``Commission'') is issuing a Handbook on Filing Procedures to replace its Handbook on Electronic...

  7. Decryption-decompression of AES protected ZIP files on GPUs

    NASA Astrophysics Data System (ADS)

    Duong, Tan Nhat; Pham, Phong Hong; Nguyen, Duc Huu; Nguyen, Thuy Thanh; Le, Hung Duc

    2011-10-01

    AES is a strong encryption system, so decryption-decompression of AES encrypted ZIP files requires very large computing power and techniques of reducing the password space. This makes implementations of techniques on common computing system not practical. In [1], we reduced the original very large password search space to a much smaller one which surely containing the correct password. Based on reduced set of passwords, in this paper, we parallel decryption, decompression and plain text recognition for encrypted ZIP files by using CUDA computing technology on graphics cards GeForce GTX295 of NVIDIA, to find out the correct password. The experimental results have shown that the speed of decrypting, decompressing, recognizing plain text and finding out the original password increases about from 45 to 180 times (depends on the number of GPUs) compared to sequential execution on the Intel Core 2 Quad Q8400 2.66 GHz. These results have demonstrated the potential applicability of GPUs in this cryptanalysis field.

  8. 12 CFR 1780.9 - Filing of papers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Filing of papers. 1780.9 Section 1780.9 Banks... papers. (a) Filing. Any papers required to be filed shall be addressed to the presiding officer and filed... Director or the presiding officer. All papers filed by electronic media shall also concurrently be filed in...

  9. 12 CFR 1780.9 - Filing of papers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 7 2011-01-01 2011-01-01 false Filing of papers. 1780.9 Section 1780.9 Banks... papers. (a) Filing. Any papers required to be filed shall be addressed to the presiding officer and filed... Director or the presiding officer. All papers filed by electronic media shall also concurrently be filed in...

  10. The Jade File System. Ph.D. Thesis

    NASA Technical Reports Server (NTRS)

    Rao, Herman Chung-Hwa

    1991-01-01

    File systems have long been the most important and most widely used form of shared permanent storage. File systems in traditional time-sharing systems, such as Unix, support a coherent sharing model for multiple users. Distributed file systems implement this sharing model in local area networks. However, most distributed file systems fail to scale from local area networks to an internet. Four characteristics of scalability were recognized: size, wide area, autonomy, and heterogeneity. Owing to size and wide area, techniques such as broadcasting, central control, and central resources, which are widely adopted by local area network file systems, are not adequate for an internet file system. An internet file system must also support the notion of autonomy because an internet is made up by a collection of independent organizations. Finally, heterogeneity is the nature of an internet file system, not only because of its size, but also because of the autonomy of the organizations in an internet. The Jade File System, which provides a uniform way to name and access files in the internet environment, is presented. Jade is a logical system that integrates a heterogeneous collection of existing file systems, where heterogeneous means that the underlying file systems support different file access protocols. Because of autonomy, Jade is designed under the restriction that the underlying file systems may not be modified. In order to avoid the complexity of maintaining an internet-wide, global name space, Jade permits each user to define a private name space. In Jade's design, we pay careful attention to avoiding unnecessary network messages between clients and file servers in order to achieve acceptable performance. Jade's name space supports two novel features: (1) it allows multiple file systems to be mounted under one direction; and (2) it permits one logical name space to mount other logical name spaces. A prototype of Jade was implemented to examine and validate its

  11. 76 FR 50210 - Combined Notice of Filings #

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-12

    ..., Inc. submits tariff filing per 35.13(a)(2)(iii: Filing of Notice of Succession to be effective 10/5..., Inc. submits tariff filing per 35.13(a)(2)(iii: Filing of Notice of Succession to be effective 10/5..., Inc. submits tariff filing per 35.13(a)(2)(iii: Filing of Notice of Succession to be effective 10/5...

  12. 76 FR 12950 - Combined Notice of Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-09

    ....204: EnCana Marketing Negotiated Rate Agreement Amendment to be effective 2/24/2011. Filed Date: 03/01... submits tariff filing per 154.403(d)(2): Fuel Filing 2011 to be effective 4/1/2011. Filed Date: 03/01/2011... submits tariff filing per 154.403(d)(2): Fuel Tracker 2011 to be effective 4/1/2011. Filed Date: 03/01...

  13. The Galley Parallel File System

    NASA Technical Reports Server (NTRS)

    Nieuwejaar, Nils; Kotz, David

    1996-01-01

    Most current multiprocessor file systems are designed to use multiple disks in parallel, using the high aggregate bandwidth to meet the growing I/0 requirements of parallel scientific applications. Many multiprocessor file systems provide applications with a conventional Unix-like interface, allowing the application to access multiple disks transparently. This interface conceals the parallelism within the file system, increasing the ease of programmability, but making it difficult or impossible for sophisticated programmers and libraries to use knowledge about their I/O needs to exploit that parallelism. In addition to providing an insufficient interface, most current multiprocessor file systems are optimized for a different workload than they are being asked to support. We introduce Galley, a new parallel file system that is intended to efficiently support realistic scientific multiprocessor workloads. We discuss Galley's file structure and application interface, as well as the performance advantages offered by that interface.

  14. 46 CFR 380.2 - Filing applications.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Filing applications. 380.2 Section 380.2 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION MISCELLANEOUS PROCEDURES Filing of Applications Under Section 805(a), 1936 Act § 380.2 Filing applications. (a) An applicant under section 805(a) shall file his...

  15. 48 CFR 1404.802 - Contract files.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Contract files. 1404.802 Section 1404.802 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL ADMINISTRATIVE MATTERS Contract Files 1404.802 Contract files. In addition to the requirements in FAR 4.802, files shall...

  16. 48 CFR 1404.802 - Contract files.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Contract files. 1404.802 Section 1404.802 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL ADMINISTRATIVE MATTERS Contract Files 1404.802 Contract files. In addition to the requirements in FAR 4.802, files shall...

  17. 48 CFR 1404.802 - Contract files.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Contract files. 1404.802 Section 1404.802 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL ADMINISTRATIVE MATTERS Contract Files 1404.802 Contract files. In addition to the requirements in FAR 4.802, files shall...

  18. 48 CFR 1404.802 - Contract files.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Contract files. 1404.802 Section 1404.802 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL ADMINISTRATIVE MATTERS Contract Files 1404.802 Contract files. In addition to the requirements in FAR 4.802, files shall...

  19. 48 CFR 1404.802 - Contract files.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract files. 1404.802 Section 1404.802 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL ADMINISTRATIVE MATTERS Contract Files 1404.802 Contract files. In addition to the requirements in FAR 4.802, files shall...

  20. 78 FR 21930 - Aquenergy Systems, Inc.; Notice of Intent To File License Application, Filing of Pre-Application...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-12

    ... Systems, Inc.; Notice of Intent To File License Application, Filing of Pre-Application Document, and Approving Use of the Traditional Licensing Process a. Type of Filing: Notice of Intent to File License...: November 11, 2012. d. Submitted by: Aquenergy Systems, Inc., a fully owned subsidiaries of Enel Green Power...

  1. 5 CFR 2422.5 - Filing petitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Filing petitions. 2422.5 Section 2422.5... FEDERAL LABOR RELATIONS AUTHORITY REPRESENTATION PROCEEDINGS § 2422.5 Filing petitions. (a) Where to file. Petitions must be filed with the Regional Director for the region in which the unit or employee(s) affected...

  2. 12 CFR 5.4 - Filing required.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Filing required. 5.4 Section 5.4 Banks and... CORPORATE ACTIVITIES Rules of General Applicability § 5.4 Filing required. (a) Filing. A depository... filings are available in the Manual and from each district office. (c) Other applications accepted. At the...

  3. 78 FR 46936 - Combined Notice of Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-02

    ...: Filings Instituting Proceedings Docket Numbers: RP13-1103-000. Applicants: Northern Border Pipeline Company. Description: ACA Filing 2013 to be effective 10/1/2013. Filed Date: 7/25/13. Accession Number... Gas Transmission System. Description: ACA Filing 2013 to be effective 10/1/2013. Filed Date: 7/25/13...

  4. TRMM .25 deg x .25 deg Gridded Precipitation Text Product

    NASA Technical Reports Server (NTRS)

    Stocker, Erich; Kelley, Owen

    2009-01-01

    Since the launch of the Tropical Rainfall Measuring Mission (TRMM), the Precipitation Measurement Missions science team has endeavored to provide TRMM precipitation retrievals in a variety of formats that are more easily usable by the broad science community than the standard Hierarchical Data Format (HDF) in which TRMM data is produced and archived. At the request of users, the Precipitation Processing System (PPS) has developed a .25 x .25 gridded product in an easily used ASCII text format. The entire TRMM mission data has been made available in this format. The paper provides the details of this new precipitation product that is designated with the TRMM designator 3G68.25. The format is packaged into daily files. It provides hourly precipitation information from the TRMM microwave imager (TMI), precipitation radar (PR), and TMI/PR combined rain retrievals. A major advantage of this approach is the inclusion only of rain data, compression when a particular grid has no rain from the PR or combined, and its direct ASCII text format. For those interested only in rain retrievals and whether rain is convection or stratiform, these products provide a huge reduction in the data volume inherent in the standard TRMM products. This paper provides examples of the 3G68 data products and their uses. It also provides information about C tools that can be used to aggregate daily files into larger time samples. In addition, it describes the possibilities inherent in the spatial sampling which allows resampling into coarser spatial sampling. The paper concludes with information about downloading the gridded text data products.

  5. Intrex Subject/Title Inverted-File Characteristics.

    ERIC Educational Resources Information Center

    Uemura, Syunsuke

    The characteristics of the Intrex subject/title inverted file are analyzed. Basic statistics of the inverted file are presented including various distributions of the index words and terms from which the file was derived, and statistics on stems, the file growth process, and redundancy measurements. A study of stems both with extremely high and…

  6. 77 FR 50738 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing and Immediate...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-22

    ... Proposed Rule Change To Remove the Expired Pilot Under Rule 4753(c) From the NASDAQ Rule Book August 16... ``Volatility Guard'') from the NASDAQ rule book. NASDAQ will remove the rule text 30 days after the filing date... proposing to remove the expired pilot under Rule 4753(c) from the rule book. On June 18, 2010, NASDAQ filed...

  7. Procarcinogenic effects of cyclosporine A are mediated through the activation of TAK1/TAB1 signaling pathway

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xu, Jianmin; Walsh, Stephanie B.; Verney, Zoe M.

    Research highlights: {yields} Organ transplant recipients are highly susceptible to early skin cancer development. {yields} CsA-mediated TGFB1-dependent TAK1/TAB1 signaling augments invasive tumor growth. {yields} CsA enhances accumulation of upstream kinases, ZMP, AMPK and IRAK to activate TAK1. {yields} TAK1 mediates enhanced proliferation and reduced apoptosis via CsA-dependent NF{kappa}B. -- Abstract: Cyclosporine A (CsA) is an immunosuppressive drug commonly used for maintaining chronic immune suppression in organ transplant recipients. It is known that patients receiving CsA manifest increased growth of aggressive non-melanoma skin cancers. However, the underlying mechanism by which CsA augments tumor growth is not fully understood. Here, we showmore » that CsA augments the growth of A431 epidermoid carcinoma xenograft tumors by activating tumor growth factor {beta}-activated kinase1 (TAK1). The activation of TAK1 by CsA occurs at multiple levels by kinases ZMP, AMPK and IRAK. TAK1 forms heterodimeric complexes with TAK binding protein 1 and 2 (TAB1/TAB2) which in term activate nuclear factor {kappa}B (NF{kappa}B) and p38 MAP kinase. Transcriptional activation of NF{kappa}B is evidenced by IKK{beta}-mediated phosphorylation-dependent degradation of I{kappa}B and consequent nuclear translocation of p65. This also leads to enhancement in the expression of its transcriptional target genes cyclin D1, Bcl2 and COX-2. Similarly, activation of p38 leads to enhanced inflammation-related signaling shown by increased phosphorylation of MAPKAPK2 and which in turn phosphorylates its substrate HSP27. Activation of both NF{kappa}B and p38 MAP kinase provide mitogenic stimuli to augment the growth of SCCs.« less

  8. Development of EnergyPlus Utility to Batch Simulate Building Energy Performance on a National Scale

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Valencia, Jayson F.; Dirks, James A.

    2008-08-29

    EnergyPlus is a simulation program that requires a large number of details to fully define and model a building. Hundreds or even thousands of lines in a text file are needed to run the EnergyPlus simulation depending on the size of the building. To manually create these files is a time consuming process that would not be practical when trying to create input files for thousands of buildings needed to simulate national building energy performance. To streamline the process needed to create the input files for EnergyPlus, two methods were created to work in conjunction with the National Renewable Energymore » Laboratory (NREL) Preprocessor; this reduced the hundreds of inputs needed to define a building in EnergyPlus to a small set of high-level parameters. The first method uses Java routines to perform all of the preprocessing on a Windows machine while the second method carries out all of the preprocessing on the Linux cluster by using an in-house built utility called Generalized Parametrics (GPARM). A comma delimited (CSV) input file is created to define the high-level parameters for any number of buildings. Each method then takes this CSV file and uses the data entered for each parameter to populate an extensible markup language (XML) file used by the NREL Preprocessor to automatically prepare EnergyPlus input data files (idf) using automatic building routines and macro templates. Using a Linux utility called “make”, the idf files can then be automatically run through the Linux cluster and the desired data from each building can be aggregated into one table to be analyzed. Creating a large number of EnergyPlus input files results in the ability to batch simulate building energy performance and scale the result to national energy consumption estimates.« less

  9. Small file aggregation in a parallel computing system

    DOEpatents

    Faibish, Sorin; Bent, John M.; Tzelnic, Percy; Grider, Gary; Zhang, Jingwang

    2014-09-02

    Techniques are provided for small file aggregation in a parallel computing system. An exemplary method for storing a plurality of files generated by a plurality of processes in a parallel computing system comprises aggregating the plurality of files into a single aggregated file; and generating metadata for the single aggregated file. The metadata comprises an offset and a length of each of the plurality of files in the single aggregated file. The metadata can be used to unpack one or more of the files from the single aggregated file.

  10. 5 CFR 1203.13 - Filing pleadings.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... delivery, by facsimile, or by e-filing in accordance with § 1201.14 of this chapter. If the document was... submitted by e-filing, it is considered to have been filed on the date of electronic submission. (e... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Filing pleadings. 1203.13 Section 1203.13...

  11. 18 CFR 385.2001 - Filings (Rule 2001).

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Filings (Rule 2001... Filings in Proceedings Before the Commission § 385.2001 Filings (Rule 2001). (a) Filings with the... filing via the Internet pursuant to Rule 2003 through the links provided at http://www.ferc.gov. Note to...

  12. Deceit: A flexible distributed file system

    NASA Technical Reports Server (NTRS)

    Siegel, Alex; Birman, Kenneth; Marzullo, Keith

    1989-01-01

    Deceit, a distributed file system (DFS) being developed at Cornell, focuses on flexible file semantics in relation to efficiency, scalability, and reliability. Deceit servers are interchangeable and collectively provide the illusion of a single, large server machine to any clients of the Deceit service. Non-volatile replicas of each file are stored on a subset of the file servers. The user is able to set parameters on a file to achieve different levels of availability, performance, and one-copy serializability. Deceit also supports a file version control mechanism. In contrast with many recent DFS efforts, Deceit can behave like a plain Sun Network File System (NFS) server and can be used by any NFS client without modifying any client software. The current Deceit prototype uses the ISIS Distributed Programming Environment for all communication and process group management, an approach that reduces system complexity and increases system robustness.

  13. 17 CFR 232.13 - Date of filing; adjustment of filing date.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Standard Time or Eastern Daylight Saving Time, whichever is currently in effect, shall be deemed filed on.... Eastern Standard Time or Eastern Daylight Saving Time, whichever is currently in effect, shall be deemed... Daylight Savings Time, whichever is currently in effect, shall be deemed filed on the same business day. (4...

  14. 17 CFR 232.13 - Date of filing; adjustment of filing date.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Standard Time or Eastern Daylight Saving Time, whichever is currently in effect, shall be deemed filed on.... Eastern Standard Time or Eastern Daylight Saving Time, whichever is currently in effect, shall be deemed... Daylight Savings Time, whichever is currently in effect, shall be deemed filed on the same business day. (4...

  15. 17 CFR 232.13 - Date of filing; adjustment of filing date.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Standard Time or Eastern Daylight Saving Time, whichever is currently in effect, shall be deemed filed on.... Eastern Standard Time or Eastern Daylight Saving Time, whichever is currently in effect, shall be deemed... Daylight Savings Time, whichever is currently in effect, shall be deemed filed on the same business day. (4...

  16. 17 CFR 232.13 - Date of filing; adjustment of filing date.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Standard Time or Eastern Daylight Saving Time, whichever is currently in effect, shall be deemed filed on.... Eastern Standard Time or Eastern Daylight Saving Time, whichever is currently in effect, shall be deemed... Daylight Savings Time, whichever is currently in effect, shall be deemed filed on the same business day. (4...

  17. 49 CFR 1104.6 - Timely filing required.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... offers next day delivery to Washington, DC. If the e-filing option is chosen (for those pleadings and documents that are appropriate for e-filing, as determined by reference to the information on the Board's Web site), then the e-filed pleading or document is timely filed if the e-filing process is completed...

  18. 10 CFR 110.89 - Filing and service.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...: Rulemakings and Adjudications Staff or via the E-Filing system, following the procedure set forth in 10 CFR 2.302. Filing by mail is complete upon deposit in the mail. Filing via the E-Filing system is completed... residence with some occupant of suitable age and discretion; (2) Following the requirements for E-Filing in...

  19. 7 CFR 989.23 - File.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false File. 989.23 Section 989.23 Agriculture Regulations of... CALIFORNIA Order Regulating Handling Definitions § 989.23 File. File means transmit or deliver to the... time: (a) Of actual receipt by the Secretary or committee in the event of personal delivery; (b) Of...

  20. 7 CFR 989.23 - File.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false File. 989.23 Section 989.23 Agriculture Regulations of... CALIFORNIA Order Regulating Handling Definitions § 989.23 File. File means transmit or deliver to the... time: (a) Of actual receipt by the Secretary or committee in the event of personal delivery; (b) Of...

  1. Incorporating uncertainty in RADTRAN 6.0 input files.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dennis, Matthew L.; Weiner, Ruth F.; Heames, Terence John

    Uncertainty may be introduced into RADTRAN analyses by distributing input parameters. The MELCOR Uncertainty Engine (Gauntt and Erickson, 2004) has been adapted for use in RADTRAN to determine the parameter shape and minimum and maximum of the distribution, to sample on the distribution, and to create an appropriate RADTRAN batch file. Coupling input parameters is not possible in this initial application. It is recommended that the analyst be very familiar with RADTRAN and able to edit or create a RADTRAN input file using a text editor before implementing the RADTRAN Uncertainty Analysis Module. Installation of the MELCOR Uncertainty Engine ismore » required for incorporation of uncertainty into RADTRAN. Gauntt and Erickson (2004) provides installation instructions as well as a description and user guide for the uncertainty engine.« less

  2. 12 CFR 908.25 - Filing of papers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 7 2011-01-01 2011-01-01 false Filing of papers. 908.25 Section 908.25 Banks... RULES OF PRACTICE AND PROCEDURE IN HEARINGS ON THE RECORD General Rules § 908.25 Filing of papers. (a) Filing. Any papers required to be filed shall be addressed to the presiding officer and filed with the...

  3. 12 CFR 908.25 - Filing of papers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Filing of papers. 908.25 Section 908.25 Banks... RULES OF PRACTICE AND PROCEDURE IN HEARINGS ON THE RECORD General Rules § 908.25 Filing of papers. (a) Filing. Any papers required to be filed shall be addressed to the presiding officer and filed with the...

  4. Phylogenetic Relationships and Species Delimitation in Pinus Section Trifoliae Inferrred from Plastid DNA

    PubMed Central

    Hernández-León, Sergio; Gernandt, David S.; Pérez de la Rosa, Jorge A.; Jardón-Barbolla, Lev

    2013-01-01

    Recent diversification followed by secondary contact and hybridization may explain complex patterns of intra- and interspecific morphological and genetic variation in the North American hard pines (Pinus section Trifoliae), a group of approximately 49 tree species distributed in North and Central America and the Caribbean islands. We concatenated five plastid DNA markers for an average of 3.9 individuals per putative species and assessed the suitability of the five regions as DNA bar codes for species identification, species delimitation, and phylogenetic reconstruction. The ycf1 gene accounted for the greatest proportion of the alignment (46.9%), the greatest proportion of variable sites (74.9%), and the most unique sequences (75 haplotypes). Phylogenetic analysis recovered clades corresponding to subsections Australes, Contortae, and Ponderosae. Sequences for 23 of the 49 species were monophyletic and sequences for another 9 species were paraphyletic. Morphologically similar species within subsections usually grouped together, but there were exceptions consistent with incomplete lineage sorting or introgression. Bayesian relaxed molecular clock analyses indicated that all three subsections diversified relatively recently during the Miocene. The general mixed Yule-coalescent method gave a mixed model estimate of only 22 or 23 evolutionary entities for the plastid sequences, which corresponds to less than half the 49 species recognized based on morphological species assignments. Including more unique haplotypes per species may result in higher estimates, but low mutation rates, recent diversification, and large effective population sizes may limit the effectiveness of this method to detect evolutionary entities. PMID:23936218

  5. Phylogenetic relationships and species delimitation in pinus section trifoliae inferrred from plastid DNA.

    PubMed

    Hernández-León, Sergio; Gernandt, David S; Pérez de la Rosa, Jorge A; Jardón-Barbolla, Lev

    2013-01-01

    Recent diversification followed by secondary contact and hybridization may explain complex patterns of intra- and interspecific morphological and genetic variation in the North American hard pines (Pinus section Trifoliae), a group of approximately 49 tree species distributed in North and Central America and the Caribbean islands. We concatenated five plastid DNA markers for an average of 3.9 individuals per putative species and assessed the suitability of the five regions as DNA bar codes for species identification, species delimitation, and phylogenetic reconstruction. The ycf1 gene accounted for the greatest proportion of the alignment (46.9%), the greatest proportion of variable sites (74.9%), and the most unique sequences (75 haplotypes). Phylogenetic analysis recovered clades corresponding to subsections Australes, Contortae, and Ponderosae. Sequences for 23 of the 49 species were monophyletic and sequences for another 9 species were paraphyletic. Morphologically similar species within subsections usually grouped together, but there were exceptions consistent with incomplete lineage sorting or introgression. Bayesian relaxed molecular clock analyses indicated that all three subsections diversified relatively recently during the Miocene. The general mixed Yule-coalescent method gave a mixed model estimate of only 22 or 23 evolutionary entities for the plastid sequences, which corresponds to less than half the 49 species recognized based on morphological species assignments. Including more unique haplotypes per species may result in higher estimates, but low mutation rates, recent diversification, and large effective population sizes may limit the effectiveness of this method to detect evolutionary entities.

  6. Effects of shade tab arrangement on the repeatability and accuracy of shade selection.

    PubMed

    Yılmaz, Burak; Yuzugullu, Bulem; Cınar, Duygu; Berksun, Semih

    2011-06-01

    Appropriate and repeatable shade matching using visual shade selection remains a challenge for the restorative dentist. The purpose of this study was to evaluate the effect of different arrangements of a shade guide on the repeatability and accuracy of visual shade selection by restorative dentists. Three Vitapan Classical shade guides were used for shade selection. Seven shade tabs from one shade guide were used as target shades for the testing (A1, A4, B2, B3, C2, C4, and D3); the other 2 guides were used for shade selection by the subjects. One shade guide was arranged according to hue and chroma and the second was arranged according to value. Thirteen male and 22 female restorative dentists were asked to match the target shades using shade guide tabs arranged in the 2 different orders. The sessions were performed twice with each guide in a viewing booth. Collected data were analyzed with Fisher's exact test to compare the accuracy and repeatability of the shade selection (α=.05). There were no significant differences observed in the accuracy or repeatability of the shade selection results obtained with the 2 different arrangements. When the hue/chroma-ordered shade guide was used, 58% of the shade selections were accurate. This ratio was 57.6% when the value-ordered shade guide was used. The observers repeated 55.5% of the selections accurately with the hue/chroma-ordered shade guide and 54.3% with the value-ordered shade guide. The accuracy and repeatability of shade selections by restorative dentists were similar when different arrangements (hue/chroma-ordered and value-ordered) of the Vitapan Classical shade guide were used. Copyright © 2011 The Editorial Council of the Journal of Prosthetic Dentistry. Published by Mosby, Inc. All rights reserved.

  7. 77 FR 38279 - Combined Notice of Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    .... Description: CO2 Gas Quality Settlement Filing of Wyoming Interstate Company, LLC. Filed Date: 6/11/12.... Description: Fuel Filing to be effective 7/1/2012. Filed Date: 6/20/12. Accession Number: 20120620-5118...

  8. Temporal and spatial distribution of Paleozoic metamorphism in the southern Appalachian Blue Ridge and Inner Piedmont delimited by ion microprobe U-Pb ages of metamorphic zircon

    USGS Publications Warehouse

    Merschat, Arthur J.; Bream, Brendan R.; Huebner, Matthew T.; Hatcher, Robert D.; Miller, Calvin F.

    2017-01-01

    Ion microprobe U-Pb zircon rim ages from 39 samples from across the accreted terranes of the central Blue Ridge, eastward across the Inner Piedmont, delimit the timing and spatial extent of superposed metamorphism in the southern Appalachian orogen. Metamorphic zircon rims are 10–40 µm wide, mostly unzoned, and dark gray to black or bright white in cathodoluminescence, and truncate and/or embay interior oscillatory zoning. Black unzoned and rounded or ovoid-shaped metamorphic zircon morphologies also occur. Th/U values range from 0.01 to 1.4, with the majority of ratios less than 0.1. Results of 206Pb/238U ages, ±2% discordant, range from 481 to 305 Ma. Clustering within these data reveals that the Blue Ridge and Inner Piedmont terranes were affected by three tectonothermal events: (1) 462–448 Ma (Taconic); (2) 395–340 Ma (Acadian and Neoacadian); and (3) 335–322 Ma, related to the early phase of the Alleghanian orogeny. By combining zircon rim ages with metamorphic isograds and other published isotopic ages, we identify the thermal architecture of the southern Appalachian orogen: juxtaposed and superposed metamorphic domains have younger ages to the east related to the marginward addition of terranes, and these domains can serve as a proxy to delimit terrane accretion. Most 462–448 Ma ages occur in the western and central Blue Ridge and define a continuous progression from greenschist to granulite facies that identifies the intact Taconic core. The extent of 462–448 Ma metamorphism indicates that the central Blue Ridge and Tugaloo terranes were accreted to the western Blue Ridge during the Taconic orogeny. Zircon rim ages in the Inner Piedmont span almost 100 m.y., with peaks at 395–385, 376–340, and 335–322 Ma, and delimit the Acadian-Neoacadian and Alleghanian metamorphic core. The timing and distribution of metamorphism in the Inner Piedmont are consistent with the Devonian to Mississippian oblique collision of the Carolina superterrane

  9. 40 CFR 22.5 - Filing, service, and form of all filed documents; business confidentiality claims.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Filing, service, and form of all filed... PENALTIES AND THE REVOCATION/TERMINATION OR SUSPENSION OF PERMITS General § 22.5 Filing, service, and form... association which is subject to suit under a common name, complainant shall serve an officer, partner, a...

  10. Integration of Text- and Data-Mining Technologies for Use in Banking Applications

    NASA Astrophysics Data System (ADS)

    Maslankowski, Jacek

    Unstructured data, most of it in the form of text files, typically accounts for 85% of an organization's knowledge stores, but it's not always easy to find, access, analyze or use (Robb 2004). That is why it is important to use solutions based on text and data mining. This solution is known as duo mining. This leads to improve management based on knowledge owned in organization. The results are interesting. Data mining provides to lead with structuralized data, usually powered from data warehouses. Text mining, sometimes called web mining, looks for patterns in unstructured data — memos, document and www. Integrating text-based information with structured data enriches predictive modeling capabilities and provides new stores of insightful and valuable information for driving business and research initiatives forward.

  11. 77 FR 74839 - Combined Notice of Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-18

    ..., LP. Description: National Grid LNG, LP submits tariff filing per 154.203: Adoption of NAESB Version 2... with Order to Amend NAESB Version 2.0 Filing to be effective 12/1/2012. Filed Date: 12/11/12. Accession...: Refile to comply with Order on NAESB Version 2.0 Filing to be effective 12/1/2012. Filed Date: 12/11/12...

  12. 77 FR 103 - JD Products, LLC; Notice of Intent To File License Application, Filing of Pre-Application...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-03

    ... Commission strongly encourages electronic filing, documents may also be paper-filed. To paper-file, mail an... needed please contact Mr. David Pryor, Senior Environmental Scientist--California State Parks, at dpryor...

  13. 40 CFR 78.4 - Filings.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... § 78.4 Filings. (a) All original filings made under this part shall be signed by the person making the... behalf of persons with an interest in allowances in a general account shall be signed by the authorized account representative. Any filings on behalf of owners and operators of a NOX Budget unit or source shall...

  14. KAnalyze: a fast versatile pipelined K-mer toolkit

    PubMed Central

    Audano, Peter; Vannberg, Fredrik

    2014-01-01

    Motivation: Converting nucleotide sequences into short overlapping fragments of uniform length, k-mers, is a common step in many bioinformatics applications. While existing software packages count k-mers, few are optimized for speed, offer an application programming interface (API), a graphical interface or contain features that make it extensible and maintainable. We designed KAnalyze to compete with the fastest k-mer counters, to produce reliable output and to support future development efforts through well-architected, documented and testable code. Currently, KAnalyze can output k-mer counts in a sorted tab-delimited file or stream k-mers as they are read. KAnalyze can process large datasets with 2 GB of memory. This project is implemented in Java 7, and the command line interface (CLI) is designed to integrate into pipelines written in any language. Results: As a k-mer counter, KAnalyze outperforms Jellyfish, DSK and a pipeline built on Perl and Linux utilities. Through extensive unit and system testing, we have verified that KAnalyze produces the correct k-mer counts over multiple datasets and k-mer sizes. Availability and implementation: KAnalyze is available on SourceForge: https://sourceforge.net/projects/kanalyze/ Contact: fredrik.vannberg@biology.gatech.edu Supplementary information: Supplementary data are available at Bioinformatics online. PMID:24642064

  15. Annual agricultural pesticide use for Midwest Stream-Quality Assessment, 2012-13

    USGS Publications Warehouse

    Baker, Nancy T.; Stone, Wesley W.

    2014-01-01

    This report provides estimates of annual agricultural use of 190 pesticide compounds for counties and selected watersheds of Midwestern States for 2012 and 2013 compiled for subsequent analysis by the National Water-Quality Assessment Program, Midwest Stream-Quality Assessment (MSQA). One of the goals of MSQA is to characterize contaminants at perennial-stream sites throughout the Corn Belt. Evaluating pesticide inputs from agricultural sources will aid in that characterization. Crop acres for selected Midwestern crops were obtained from the Cropland Data Layer of the U.S. Department of Agriculture’s National Agricultural Statistics Service and used in conjunction with GfK Kynetec, Inc. proprietary Crop Reporting District-level pesticide-use data to estimate pesticide use for counties and watersheds. Estimated pesticide use (EPest) values were calculated by using both the “EPest-high” and “EPest-low” methods, the distinction being that there are more counties with estimated pesticide use for EPest-high compared to EPest-low, owing to differing assumptions about missing survey data. County-level and watershed-level estimates of annual agricultural pesticide use are provided as downloadable, tab-delimited files for both EPest-high and Epest-low. Summary graphs of MSQA watershed-level pesticide use for selected crops are also provided.

  16. Preliminary estimates of annual agricultural pesticide use for counties of the conterminous United States, 2010-11

    USGS Publications Warehouse

    Baker, Nancy T.; Stone, Wesley W.

    2013-01-01

    This report provides preliminary estimates of annual agricultural use of 374 pesticide compounds in counties of the conterminous United States in 2010 and 2011, compiled by means of methods described in Thelin and Stone (2013). U.S. Department of Agriculture (USDA) county-level data for harvested-crop acreage were used in conjunction with proprietary Crop Reporting District (CRD)-level pesticide-use data to estimate county-level pesticide use. Estimated pesticide use (EPest) values were calculated with both the EPest-high and EPest-low methods. The distinction between the EPest-high method and the EPest-low method is that there are more counties with estimated pesticide use for EPest-high compared to EPest-low, owing to differing assumptions about missing survey data (Thelin and Stone, 2013). Preliminary estimates in this report will be revised upon availability of updated crop acreages in the 2012 Agricultural Census, to be published by the USDA in 2014. In addition, estimates for 2008 and 2009 previously published by Stone (2013) will be updated subsequent to the 2012 Agricultural Census release. Estimates of annual agricultural pesticide use are provided as downloadable, tab-delimited files, which are organized by compound, year, state Federal Information Processing Standard (FIPS) code, county FIPS code, and kg (amount in kilograms).

  17. Merged Federal Files [Academic Year] 1978-79 [machine-readable data file].

    ERIC Educational Resources Information Center

    National Center for Education Statistics (ED), Washington, DC.

    The Merged Federal File for 1978-79 contains school district level data from the following six source files: (1) the Census of Governments' Survey of Local Government Finances--School Systems (F-33) (with 16,343 records merged); (2) the National Center for Education Statistics Survey of School Systems (School District Universe) (with 16,743…

  18. Randomized Controlled Trial of Daily Text Messages to Support Adherence to Preexposure Prophylaxis in Individuals at Risk for Human Immunodeficiency Virus: The TAPIR Study.

    PubMed

    Moore, David J; Jain, Sonia; Dubé, Michael P; Daar, Eric S; Sun, Xiaoying; Young, Jason; Corado, Katya; Ellorin, Eric; Milam, Joel; Collins, Deborah; Blumenthal, Jill; Best, Brookie M; Anderson, Peter; Haubrich, Richard; Morris, Sheldon R

    2018-05-02

    Adherence is critical for efficacy of tenofovir disoproxil fumarate/emtricitabine (FTC) as preexposure prophylaxis (PrEP). Between February 2013 and February 2016, 398 men who have sex with men and transgender women were randomized 1:1 to receive individualized texting for adherence building (iTAB) or standard care (SoC) for 48 weeks. The primary endpoint was dried blood spot (DBS) tenofovir diphosphate (TFV-DP) concentrations at both week 12 and the last on-drug visit of >719 fmol/punch (ie, adequate adherence). Secondary outcomes included DBS TFV-DP concentrations of >1246 fmol/punch (ie, near-perfect adherence) and plasma FTC >350 ng/mL (consistent with dosing within the past 24 hours). Concentrations >719 fmol/punch of TFV-DP were found in 88.6% of participants at week 12 and 82.5% at week 48. For the primary endpoint, the study arms did not differ (72.0% in iTAB and 69.2% in SoC; P > .05). For the secondary composite endpoint of >1246 fmol/punch the iTAB arm was superior to SoC (33.5% vs 24.8%; P = .06), reaching statistical significance when adjusting for age (odds ratio, 1.56 [95% confidence interval, 1.00-2.42]; P < .05). At week 48, iTAB was superior to SoC for near-perfect adherence (51.0% vs 37.4%; P = .02). At week 12, iTAB was superior to SoC for dosing in past 24 hours by plasma FTC (47.5% vs 33.3%; P = .007), but not at weeks 24, 36, and 48 (all P > .05). Automated text messaging is a low-burden tool that improves durability of near-perfect PrEP adherence. NCT01761643.

  19. 12 CFR 303.8 - Public access to filing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... portions of a filing (the public file) until 180 days following final disposition of a filing. Following the 180-day period, non-confidential portions of an application file will be made available in accordance with ' 303.8(c). The public file generally consists of portions of the filing, supporting data...

  20. 12 CFR 303.8 - Public access to filing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... portions of a filing (the public file) until 180 days following final disposition of a filing. Following the 180-day period, non-confidential portions of an application file will be made available in accordance with ' 303.8(c). The public file generally consists of portions of the filing, supporting data...

  1. 76 FR 60950 - Self-Regulatory Organizations; National Securities Clearing Corporation; Notice of Filing and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-30

    ....19b-4. \\3\\ The text of the proposed rule change is attached as Exhibit 5 to NSCC's filing, which is... any comments it received on the proposed rule change. The text of these statements may be examined at... the text of the summaries prepared by NSCC. (A) Self-Regulatory Organization's Statement of the...

  2. 77 FR 51985 - Archon Energy 1, Inc.; Notice of Intent To File License Application, Filing of Pre-Application...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-28

    ..., Inc.; Notice of Intent To File License Application, Filing of Pre-Application Document, and Approving... Application and Request to Use the Traditional Licensing Process. b. Project No.: 14432-000. c. Date Filed... Endangered Species Act. m. Archon filed a Pre-Application Document (PAD) with the Commission, pursuant to 18...

  3. 77 FR 61585 - FPL Energy Maine Hydro LLC; Notice of Intent To File License Application, Filing of Pre...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-10

    ... Hydro LLC; Notice of Intent To File License Application, Filing of Pre-Application Document (PAD... Application for a New License and Commencing Pre-filing Process. b. Project No.: 2531-067. c. Dated Filed... Commission a Pre-Application Document (PAD; including a proposed process plan and schedule), pursuant to 18...

  4. 77 FR 61584 - FFP Missouri 12, LLC; Notice of Intent To File License Application, Filing of Pre-Application...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-10

    ..., LLC; Notice of Intent To File License Application, Filing of Pre-Application Document, and Approving... Application and Request to Use the Traditional Licensing Process. b. Project No.: 13755-001. c. Date Filed.... m. Free Flow Power filed a Pre-Application Document (PAD; including a proposed process plan and...

  5. Virtual file system for PSDS

    NASA Technical Reports Server (NTRS)

    Runnels, Tyson D.

    1993-01-01

    This is a case study. It deals with the use of a 'virtual file system' (VFS) for Boeing's UNIX-based Product Standards Data System (PSDS). One of the objectives of PSDS is to store digital standards documents. The file-storage requirements are that the files must be rapidly accessible, stored for long periods of time - as though they were paper, protected from disaster, and accumulative to about 80 billion characters (80 gigabytes). This volume of data will be approached in the first two years of the project's operation. The approach chosen is to install a hierarchical file migration system using optical disk cartridges. Files are migrated from high-performance media to lower performance optical media based on a least-frequency-used algorithm. The optical media are less expensive per character stored and are removable. Vital statistics about the removable optical disk cartridges are maintained in a database. The assembly of hardware and software acts as a single virtual file system transparent to the PSDS user. The files are copied to 'backup-and-recover' media whose vital statistics are also stored in the database. Seventeen months into operation, PSDS is storing 49 gigabytes. A number of operational and performance problems were overcome. Costs are under control. New and/or alternative uses for the VFS are being considered.

  6. 75 FR 81594 - Combined Notice of Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-28

    ... Pipeline Company submits tariff filing per 154.204: RP11-20 TOC Update to be effective 10/1/2010. Filed... filing per 154.204: RP11-1474 TOC Update to be effective 11/1/2010. Filed Date: 12/16/2010. Accession...

  7. [Master files: less paper, more substance. Special rules for special medicines: Plasma Master File and Vaccine Antigen Master File].

    PubMed

    Seitz, Rainer; Haase, M

    2008-07-01

    The process of reviewing the European pharmaceutical legislation resulted in a codex, which contains two new instruments related to marketing authorisation of biological medicines: Plasma Master File (PMF) and Vaccine Antigen Master File (VAMF). In the manufacture of plasma derivatives (e. g. coagulation factors, albumin, immunoglobulins), usually the same starting material, i. e. a plasma pool, is used for several products. In the case of vaccines, the same active substance, i.e. vaccine antigen, may be included in several combination vaccine products. The intention behind the introduction of PMF and VAMF was to avoid unnecessary and redundant documentation, and to improve and harmonise assessment by means of procedures for certification of master files on the community level.

  8. Radiology teaching file cases on the World Wide Web.

    PubMed

    Scalzetti, E M

    1997-08-01

    The presentation of a radiographic teaching file on the World Wide Web can be enhanced by attending to principles of web design. Chief among these are appropriate control of page layout, minimization of the time required to download a page from the remote server, and provision for navigation within and among the web pages that constitute the site. Page layout is easily accomplished by the use of tables; column widths can be fixed to maintain an acceptable line length for text. Downloading time is minimized by rigorous editing and by optimal compression of image files; beyond this, techniques like preloading of images and specification of image width and height are also helpful. Navigation controls should be clear, consistent, and readily available.

  9. 76 FR 49761 - Combined Notice of Filings #1

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-11

    ... Operator, Inc. submits tariff filing per 35.13(a)(2)(iii: Filing of Notice of Succession to Interconnection.... submits tariff filing per 35.13(a)(2)(iii: Filing of Notice of Succession of ITC Midwest to be effective.... submits tariff filing per 35.13(a)(2)(iii: Notice of Succession to be effective 10/4/2011. Filed Date: 08...

  10. 77 FR 23708 - Combined Notice of Filings #2

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-20

    ... Company submits tariff filing per 35.13(a)(2)(iii: 7--20120413 OPCo OATT Conc to be effective 1/1/2012... tariff filing per 35: ER12-247 Compliance Filing to be effective 4/20/2011. Filed Date: 4/13/12... Compliance Filing to be effective 4/20/2011. Filed Date: 4/13/12. Accession Number: 20120413-5145. Comments...

  11. 1995 Joseph E. Whitley, MD, Award. A World Wide Web gateway to the radiologic learning file.

    PubMed

    Channin, D S

    1995-12-01

    Computer networks in general, and the Internet specifically, are changing the way information is manipulated in the world at large and in radiology. The goal of this project was to develop a computer system in which images from the Radiologic Learning File, available previously only via a single-user laser disc, are made available over a generic, high-availability computer network to many potential users simultaneously. Using a networked workstation in our laboratory and freely available distributed hypertext software, we established a World Wide Web (WWW) information server for radiology. Images from the Radiologic Learning File are requested through the WWW client software, digitized from a single laser disc containing the entire teaching file and then transmitted over the network to the client. The text accompanying each image is incorporated into the transmitted document. The Radiologic Learning File is now on-line, and requests to view the cases result in the delivery of the text and images. Image digitization via a frame grabber takes 1/30th of a second. Conversion of the image to a standard computer graphic format takes 45-60 sec. Text and image transmission speed on a local area network varies between 200 and 400 kilobytes (KB) per second depending on the network load. We have made images from a laser disc of the Radiologic Learning File available through an Internet-based hypertext server. The images previously available through a single-user system located in a remote section of our department are now ubiquitously available throughout our department via the department's computer network. We have thus converted a single-user, limited functionality system into a multiuser, widely available resource.

  12. Root canal shaping with manual stainless steel files and rotary Ni-Ti files performed by students.

    PubMed

    Sonntag, D; Guntermann, A; Kim, S K; Stachniss, V

    2003-04-01

    To investigate root canal shaping with manual stainless steel files and rotary Ni-Ti files by students. Two hundred and ten simulated root canals with the same geometrical shape and size in acrylic resin blocks were prepared by 21 undergraduate dental students with manual stainless steel files using a stepback technique or with rotary Ni-Ti files in crown-down technique. Preparation length, canal shape, incidence of fracture and preparation time were investigated. Zips and elbows occurred significantly (P < 0.001) less frequently with rotary than with manual preparation. The correct preparation length was achieved significantly (P < 0.05) more often with rotary Ni-Ti files than with manual stainless steel files. Fractures occurred significantly (P < 0.05) less frequently with hand instrumentation. The mean time required for manual preparation was significantly (P < 0.001) longer than that required for rotary preparation. Prior experience with a hand preparation technique was not reflected in an improved quality of the subsequent engine-driven preparation. Inexperienced operators achieved better canal preparations with rotary Ni-Ti instruments than with manual stainless steel files. However, rotary preparation was associated with significantly more fractures.

  13. DMFS: A Data Migration File System for NetBSD

    NASA Technical Reports Server (NTRS)

    Studenmund, William

    1999-01-01

    I have recently developed dmfs, a Data Migration File System, for NetBSD. This file system is based on the overlay file system, which is discussed in a separate paper, and provides kernel support for the data migration system being developed by my research group here at NASA/Ames. The file system utilizes an underlying file store to provide the file backing, and coordinates user and system access to the files. It stores its internal meta data in a flat file, which resides on a separate file system. Our data migration system provides archiving and file migration services. System utilities scan the dmfs file system for recently modified files, and archive them to two separate tape stores. Once a file has been doubly archived, files larger than a specified size will be truncated to that size, potentially freeing up large amounts of the underlying file store. Some sites will choose to retain none of the file (deleting its contents entirely from the file system) while others may choose to retain a portion, for instance a preamble describing the remainder of the file. The dmfs layer coordinates access to the file, retaining user-perceived access and modification times, file size, and restricting access to partially migrated files to the portion actually resident. When a user process attempts to read from the non-resident portion of a file, it is blocked and the dmfs layer sends a request to a system daemon to restore the file. As more of the file becomes resident, the user process is permitted to begin accessing the now-resident portions of the file. For simplicity, our data migration system divides a file into two portions, a resident portion followed by an optional non-resident portion. Also, a file is in one of three states: fully resident, fully resident and archived, and (partially) non-resident and archived. For a file which is only partially resident, any attempt to write or truncate the file, or to read a non-resident portion, will trigger a file restoration

  14. 18 CFR 35.7 - Electronic filing requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Electronic filing... § 35.7 Electronic filing requirements. (a) General rule. All filings made in proceedings initiated... declarations or statements and electronic signatures. (c) Format requirements for electronic filing. The...

  15. 18 CFR 35.7 - Electronic filing requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Electronic filing... § 35.7 Electronic filing requirements. (a) General rule. All filings made in proceedings initiated... declarations or statements and electronic signatures. (c) Format requirements for electronic filing. The...

  16. 18 CFR 35.7 - Electronic filing requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Electronic filing... § 35.7 Electronic filing requirements. (a) General rule. All filings made in proceedings initiated... declarations or statements and electronic signatures. (c) Format requirements for electronic filing. The...

  17. 18 CFR 35.7 - Electronic filing requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Electronic filing... § 35.7 Electronic filing requirements. (a) General rule. All filings made in proceedings initiated... declarations or statements and electronic signatures. (c) Format requirements for electronic filing. The...

  18. 78 FR 21925 - Combined Notice of Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-12

    ... comment date. The filings are accessible in the Commission's eLibrary system by clicking on the links or querying the docket number. eFiling is encouraged. More detailed information relating to filing... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Combined Notice of Filings Take notice...

  19. File concepts for parallel I/O

    NASA Technical Reports Server (NTRS)

    Crockett, Thomas W.

    1989-01-01

    The subject of input/output (I/O) was often neglected in the design of parallel computer systems, although for many problems I/O rates will limit the speedup attainable. The I/O problem is addressed by considering the role of files in parallel systems. The notion of parallel files is introduced. Parallel files provide for concurrent access by multiple processes, and utilize parallelism in the I/O system to improve performance. Parallel files can also be used conventionally by sequential programs. A set of standard parallel file organizations is proposed, organizations are suggested, using multiple storage devices. Problem areas are also identified and discussed.

  20. Health economic value of an innovation: delimiting the scope and framework of future market entry agreements.

    PubMed

    Launois, Robert; Navarrete, Lucia Fiestas; Ethgen, Olivier; Le Moine, Jean-Gabriel; Gatsinga, René

    2014-01-01

    The objective of our paper is to offer a new, payer-friendly taxonomy of market entry agreements (MEAs) that aims to twin contracts with their methodological designs in an effort to clarify the distinction between contracts that are based on performance and those that are based on demonstrated effect. Our analysis proceeds in two stages: First, we delimit the scope and framework of pay for performance (P4P) and pay for demonstrated effect (P4E) agreements. Second, we distinguish the methodological designs supporting the implementation of each of these contracts. We elucidate why P4P contracts prevent the payer from funding the true effectiveness of an innovation by expanding on their limitations. These include: 1) the normative nature of comparisons, 2) the impossibility of true effect imputability for each individual, and 3) the use of intermediary outcome measures. We then explore three main criticisms that payers must take into account when reasoning in terms of performance rather than in terms of the product effectiveness. The potential effect that performance-based reimbursements may have on dissociating the components of the cost-effectiveness ratio constitutes an obstacle to a true health economic reasoning.

  1. Preservation of root canal anatomy using self-adjusting file instrumentation with glide path prepared by 20/0.02 hand files versus 20/0.04 rotary files

    PubMed Central

    Jain, Niharika; Pawar, Ajinkya M.; Ukey, Piyush D.; Jain, Prashant K.; Thakur, Bhagyashree; Gupta, Abhishek

    2017-01-01

    Objectives: To compare the relative axis modification and canal concentricity after glide path preparation with 20/0.02 hand K-file (NITIFLEX®) and 20/0.04 rotary file (HyFlex™ CM) with subsequent instrumentation with 1.5 mm self-adjusting file (SAF). Materials and Methods: One hundred and twenty ISO 15, 0.02 taper, Endo Training Blocks (Dentsply Maillefer, Ballaigues, Switzerland) were acquired and randomly divided into following two groups (n = 60): group 1, establishing glide path till 20/0.02 hand K-file (NITIFLEX®) followed by instrumentation with 1.5 mm SAF; and Group 2, establishing glide path till 20/0.04 rotary file (HyFlex™ CM) followed by instrumentation with 1.5 mm SAF. Pre- and post-instrumentation digital images were processed with MATLAB R 2013 software to identify the central axis, and then superimposed using digital imaging software (Picasa 3.0 software, Google Inc., California, USA) taking five landmarks as reference points. Student's t-test for pairwise comparisons was applied with the level of significance set at 0.05. Results: Training blocks instrumented with 20/0.04 rotary file and SAF were associated less deviation in canal axis (at all the five marked points), representing better canal concentricity compared to those, in which glide path was established by 20/0.02 hand K-files followed by SAF instrumentation. Conclusion: Canal geometry is better maintained after SAF instrumentation with a prior glide path established with 20/0.04 rotary file. PMID:28855752

  2. 76 FR 41331 - Application Filing Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-13

    ... DEPARTMENT OF THE TREASURY Office of Thrift Supervision Application Filing Requirements AGENCY... following information collection. Title of Proposal: Application Filing Requirements. OMB Number: 1550-0056. Form Number: N/A. Description: OTS regulations require that applications, notices, or other filings...

  3. Agreement between digital image analysis and clinical spectrophotometer in CIEL*C*h° coordinate differences and total color difference (ΔE) measurements of dental ceramic shade tabs.

    PubMed

    Farah, Ra'fat I

    2016-01-01

    The objectives of this in vitro study were: 1) to test the agreement among color coordinate differences and total color difference (ΔL*, ΔC*, Δh°, and ΔE) measurements obtained by digital image analysis (DIA) and spectrophotometer, and 2) to test the reliability of each method for obtaining color differences. A digital camera was used to record standardized images of each of the 15 shade tabs from the IPS e.max shade guide placed edge-to-edge in a phantom head with a reference shade tab. The images were analyzed using image-editing software (Adobe Photoshop) to obtain the color differences between the middle area of each test shade tab and the corresponding area of the reference tab. The color differences for the same shade tab areas were also measured using a spectrophotometer. To assess the reliability, measurements for the 15 shade tabs were repeated twice using the two methods. The Intraclass Correlation Coefficient (ICC) and the Dahlberg index were used to calculate agreement and reliability. The total agreement of the two methods for measuring ΔL*, ΔC*, Δh°, and ΔE, according to the ICC, exceeded 0.82. The Dahlberg indices for ΔL* and ΔE were 2.18 and 2.98, respectively. For the reliability calculation, the ICCs for the DIA and the spectrophotometer ΔE were 0.91 and 0.94, respectively. High agreement was obtained between the DIA and spectrophotometer results for the ΔL*, ΔC*, Δh°, and ΔE measurements. Further, the reliability of the measurements for the spectrophotometer was slightly higher than the reliability of all measurements in the DIA.

  4. 78 FR 57374 - Combined Notice of Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-18

    ...: Kinetica Energy Express, LLC. Description: Kinetica Energy Express, LLC submits tariff filing per 154.203: Kinetica Energy Express LLC--FERC Gas Tariff--Volume 1 A Baseline Filing to be effective 9/1/2013. Filed... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Combined Notice of Filings Take notice...

  5. Evaluation of canal transportation after preparation with Reciproc single-file systems with or without glide path files.

    PubMed

    Aydin, Ugur; Karataslioglu, Emrah

    2017-01-01

    Canal transportation is a common sequel caused by rotary instruments. The purpose of the present study is to evaluate the degree of transportation after the use of Reciproc single-file instruments with or without glide path files. Thirty resin blocks with L-shaped canals were divided into three groups ( n = 10). Group 1 - canals were prepared with Reciproc-25 file. Group 2 - glide path file-G1 was used before Reciproc. Group 3 - glide path files-G1 and G2 were used before Reciproc. Pre- and post-instrumentation images were superimposed under microscope, and resin removed from the inner and outer surfaces of the root canal was calculated throughout 10 points. Statistical analysis was performed with Kruskal-Wallis test and post hoc Dunn test. For coronal and middle one-thirds, there was no significant difference among groups ( P > 0.05). For apical section, transportation of Group 1 was significantly higher than other groups ( P < 0.05). Using glide path files before Reciproc single-file system reduced the degree of apical canal transportation.

  6. 22 CFR 123.22 - Filing, retention, and return of export licenses and filing of export information.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Filing, retention, and return of export licenses and filing of export information. 123.22 Section 123.22 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS LICENSES FOR THE EXPORT OF DEFENSE ARTICLES § 123.22 Filing, retention...

  7. 22 CFR 123.22 - Filing, retention, and return of export licenses and filing of export information.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Filing, retention, and return of export licenses and filing of export information. 123.22 Section 123.22 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS LICENSES FOR THE EXPORT OF DEFENSE ARTICLES § 123.22 Filing, retention...

  8. 22 CFR 123.22 - Filing, retention, and return of export licenses and filing of export information.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Filing, retention, and return of export licenses and filing of export information. 123.22 Section 123.22 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS LICENSES FOR THE EXPORT OF DEFENSE ARTICLES § 123.22 Filing, retention...

  9. 22 CFR 123.22 - Filing, retention, and return of export licenses and filing of export information.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Filing, retention, and return of export licenses and filing of export information. 123.22 Section 123.22 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS LICENSES FOR THE EXPORT OF DEFENSE ARTICLES § 123.22 Filing, retention...

  10. 10 CFR 2.302 - Filing of documents.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... this part shall be electronically transmitted through the E-Filing system, unless the Commission or... all methods of filing have been completed. (e) For filings by electronic transmission, the filer must... digital ID certificates, the NRC permits participants in the proceeding to access the E-Filing system to...

  11. 77 FR 1481 - Combined Notice of Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-10

    ...: Filings Instituting Proceedings Docket Numbers: RP12-276-000. Applicants: Gulf Crossing Pipeline Company LLC. Description: Gulf Crossing Pipeline Company LLC submits tariff filing per 154.204: Antero 2 to Tenaska 243 Capacity Release Negotiated Rate Agreement Filing to be effective 1/1/2012. Filed Date: 1/3/12...

  12. 78 FR 55246 - Combined Notice of Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-10

    ... that the Commission has received the following Natural Gas Pipeline Rate and Refund Report filings: Filings Instituting Proceedings Docket Numbers: RP13-1290-000. Applicants: MoGas Pipeline LLC. Description: Annual Fuel and Gas Loss Retention Percentage Adjustment Filing to be effective 10/1/2013. Filed Date: 8...

  13. 48 CFR 204.802 - Contract files.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Contract files. 204.802 Section 204.802 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.802 Contract files. Official contract...

  14. 48 CFR 204.802 - Contract files.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Contract files. 204.802 Section 204.802 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.802 Contract files. Official contract...

  15. 48 CFR 204.802 - Contract files.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Contract files. 204.802 Section 204.802 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.802 Contract files. Official contract...

  16. 48 CFR 204.802 - Contract files.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Contract files. 204.802 Section 204.802 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.802 Contract files. Official contract...

  17. 48 CFR 204.802 - Contract files.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Contract files. 204.802 Section 204.802 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Files 204.802 Contract files. Official contract...

  18. High School and Beyond: Twins and Siblings' File Users' Manual, User's Manual for Teacher Comment File, Friends File Users' Manual.

    ERIC Educational Resources Information Center

    National Center for Education Statistics (ED), Washington, DC.

    These three users' manuals are for specific files of the High School and Beyond Study, a national longitudinal study of high school sophomores and seniors in 1980. The three files are computerized databases that are available on magnetic tape. As one component of base year data collection, information identifying twins, triplets, and some non-twin…

  19. 32 CFR 727.14 - Files and records.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 5 2012-07-01 2012-07-01 false Files and records. 727.14 Section 727.14 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY PERSONNEL LEGAL ASSISTANCE § 727.14 Files and records. (a) Case files. The material contained in legal assistance case files is...

  20. 19 CFR 201.8 - Filing of documents.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 3 2013-04-01 2013-04-01 false Filing of documents. 201.8 Section 201.8 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES OF GENERAL APPLICATION Initiation and Conduct of Investigations § 201.8 Filing of documents. (a) Applicability; where to file; date of filing...

  1. 19 CFR 201.8 - Filing of documents.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 3 2014-04-01 2014-04-01 false Filing of documents. 201.8 Section 201.8 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES OF GENERAL APPLICATION Initiation and Conduct of Investigations § 201.8 Filing of documents. (a) Applicability; where to file; date of filing...

  2. 77 FR 20812 - Combined Notice of Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-06

    ...: Trailblazer Pipeline Company LLC. Description: Negotiated Rate Filing--United Energy to be effective 4/1/2012... Company, LP. Description: Sequent 39412 Negotiated Rate Agreement Filing to be effective 4/1/2012. Filed... Energy Company FA0845 to be effective 4/1/ 2012. Filed Date: 3/29/12. Accession Number: 20120329-5032...

  3. 77 FR 35371 - Combined Notice of Filings #1

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-13

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Combined Notice of Filings 1 Take notice.... Applicants: Duke Energy Miami Fort, LLC. Description: MBR Filing to be effective 10/1/2012. Filed Date: 6/5...-000. Applicants: Duke Energy Piketon, LLC. Description: MBR Filing to be effective 10/1/2012. Filed...

  4. 47 CFR 2.1205 - Filing of required declaration.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Interference § 2.1205 Filing of required declaration. (a) For points of entry where electronic filing with... electronic filing with Customs is available, submit the following information to Customs when filing the... Customs for electronic filing. (i) The terms under which the device is being imported, as indicated by...

  5. Using Exploratory and Confirmatory Factor Analysis to Measure Construct Validity of the Traits, Aptitudes, and Behaviors Scale (TABS)

    ERIC Educational Resources Information Center

    Besnoy, Kevin D.; Dantzler, John; Besnoy, Lisa R.; Byrne, Caitlin

    2016-01-01

    This study evaluated the construct validity of the Traits, Aptitudes, and Behaviors Scale (TABS). Data for this study were collected from two separate school districts across three different academic years in the Southeastern United States. Of the total sample (N = 2,330), 64.6% of the children were identified as African American, 29.0% as…

  6. Reporting Differences Between Spacecraft Sequence Files

    NASA Technical Reports Server (NTRS)

    Khanampompan, Teerapat; Gladden, Roy E.; Fisher, Forest W.

    2010-01-01

    A suite of computer programs, called seq diff suite, reports differences between the products of other computer programs involved in the generation of sequences of commands for spacecraft. These products consist of files of several types: replacement sequence of events (RSOE), DSN keyword file [DKF (wherein DSN signifies Deep Space Network)], spacecraft activities sequence file (SASF), spacecraft sequence file (SSF), and station allocation file (SAF). These products can include line numbers, request identifications, and other pieces of information that are not relevant when generating command sequence products, though these fields can result in the appearance of many changes to the files, particularly when using the UNIX diff command to inspect file differences. The outputs of prior software tools for reporting differences between such products include differences in these non-relevant pieces of information. In contrast, seq diff suite removes the fields containing the irrelevant pieces of information before processing to extract differences, so that only relevant differences are reported. Thus, seq diff suite is especially useful for reporting changes between successive versions of the various products and in particular flagging difference in fields relevant to the sequence command generation and review process.

  7. Personal File Management for the Health Sciences.

    ERIC Educational Resources Information Center

    Apostle, Lynne

    Written as an introduction to the concepts of creating a personal or reprint file, this workbook discusses both manual and computerized systems, with emphasis on the preliminary groundwork that needs to be done before starting any filing system. A file assessment worksheet is provided; considerations in developing a personal filing system are…

  8. 12 CFR 509.10 - Filing of papers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Filing of papers. 509.10 Section 509.10 Banks... IN ADJUDICATORY PROCEEDINGS Uniform Rules of Practice and Procedure § 509.10 Filing of papers. (a) Filing. Any papers required to be filed, excluding documents produced in response to a discovery request...

  9. 12 CFR 509.10 - Filing of papers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 5 2011-01-01 2011-01-01 false Filing of papers. 509.10 Section 509.10 Banks... IN ADJUDICATORY PROCEEDINGS Uniform Rules of Practice and Procedure § 509.10 Filing of papers. (a) Filing. Any papers required to be filed, excluding documents produced in response to a discovery request...

  10. 10 CFR 1003.51 - What to file.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false What to file. 1003.51 Section 1003.51 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICE OF HEARINGS AND APPEALS PROCEDURAL REGULATIONS Modification or Rescission § 1003.51 What to file. A person filing under this subpart shall file an “Application for...

  11. 77 FR 56833 - Combined Notice of Filings #1

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-14

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Combined Notice of Filings 1 Take notice... revisions compliance filing to be effective 9/1/2012. Filed Date: 8/29/12. Accession Number: 20120830-5007... Company. Description: SEGCO 2012 PBOP Filing to be effective 1/1/2012. Filed Date: 8/29/12. Accession...

  12. 47 CFR 1.10006 - Is electronic filing mandatory?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false Is electronic filing mandatory? 1.10006 Section... International Bureau Filing System § 1.10006 Is electronic filing mandatory? Electronic filing is mandatory for... System (IBFS) form is available. Applications for which an electronic form is not available must be filed...

  13. 47 CFR 61.14 - Method of filing publications.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 3 2014-10-01 2014-10-01 false Method of filing publications. 61.14 Section 61...) TARIFFS Rules for Electronic Filing § 61.14 Method of filing publications. (a) Publications filed... date of a publication received by the Electronic Tariff Filing System will be determined by the date...

  14. 77 FR 60419 - Lock + Hydro Friends Fund XIX, LLC; Notice of Intent To File License Application, Filing of Pre...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-03

    ... Friends Fund XIX, LLC; Notice of Intent To File License Application, Filing of Pre-Application Document.... Date Filed: August 7, 2012. d. Submitted By: Lock + Hydro Friends Fund XIX, LLC. e. Name of Project.... Lock + Hydro Friends Fund XIX, LLC filed its request to use the Traditional Licensing Process on August...

  15. 46 CFR 530.5 - Duty to file.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Duty to file. 530.5 Section 530.5 Shipping FEDERAL... Provisions § 530.5 Duty to file. (a) The duty under this part to file service contracts, amendments and... conditions as the parties may agree. (c) Registration—(1) Application. Authority to file or delegate the...

  16. 46 CFR 530.5 - Duty to file.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 9 2011-10-01 2011-10-01 false Duty to file. 530.5 Section 530.5 Shipping FEDERAL... Provisions § 530.5 Duty to file. (a) The duty under this part to file service contracts, amendments and... conditions as the parties may agree. (c) Registration—(1) Application. Authority to file or delegate the...

  17. 77 FR 56197 - Combined Notice of Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-12

    ... Transmission Northwest LLC. Description: Revising Creditworthiness Language to be effective 10/ 1/2012. Filed...-12 to be effective 10/1/2012. Filed Date: 8/31/12. Accession Number: 20120831-5051. Comments Due: 5 p.... Description: Fuel Filing on 8-31-12 to be effective 10/1/2012. Filed Date: 8/31/12. Accession Number: 20120831...

  18. 14 CFR 16.13 - Filing of documents.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... previously agreed with the complainant in writing to participate in electronic filing. Documents may be filed... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Filing of documents. 16.13 Section 16.13..., Proceedings Initiated by the FAA, and Appeals § 16.13 Filing of documents. Except as otherwise provided in...

  19. 12 CFR 263.10 - Filing of papers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Filing of papers. 263.10 Section 263.10 Banks... OF PRACTICE FOR HEARINGS Uniform Rules of Practice and Procedure § 263.10 Filing of papers. (a) Filing. Any papers required to be filed, excluding documents produced in response to a discovery request...

  20. 12 CFR 263.10 - Filing of papers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 3 2011-01-01 2011-01-01 false Filing of papers. 263.10 Section 263.10 Banks... OF PRACTICE FOR HEARINGS Uniform Rules of Practice and Procedure § 263.10 Filing of papers. (a) Filing. Any papers required to be filed, excluding documents produced in response to a discovery request...

  1. 12 CFR 308.10 - Filing of papers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Filing of papers. 308.10 Section 308.10 Banks... AND PROCEDURE Uniform Rules of Practice and Procedure § 308.10 Filing of papers. (a) Filing. Any papers required to be filed, excluding documents produced in response to a discovery request pursuant to...

  2. 12 CFR 308.10 - Filing of papers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 4 2011-01-01 2011-01-01 false Filing of papers. 308.10 Section 308.10 Banks... AND PROCEDURE Uniform Rules of Practice and Procedure § 308.10 Filing of papers. (a) Filing. Any papers required to be filed, excluding documents produced in response to a discovery request pursuant to...

  3. 17 CFR 20.5 - Series S filings.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Series S filings. 20.5 Section... FOR PHYSICAL COMMODITY SWAPS § 20.5 Series S filings. (a) 102S filing. (1) When a counterparty... 102S filing only once for each counterparty, even if such persons at various times have multiple...

  4. 10 CFR 205.81 - What to file.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false What to file. 205.81 Section 205.81 Energy DEPARTMENT OF ENERGY OIL ADMINISTRATIVE PROCEDURES AND SANCTIONS Interpretation § 205.81 What to file. (a) A person filing under this subpart shall file a “Request for Interpretation,” which should be clearly labeled as...

  5. 10 CFR 1003.41 - What to file.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false What to file. 1003.41 Section 1003.41 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICE OF HEARINGS AND APPEALS PROCEDURAL REGULATIONS Stays § 1003.41 What to file. A person filing under this subpart shall file an “Application for Stay” which should be clearly...

  6. 10 CFR 1003.32 - What to file.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false What to file. 1003.32 Section 1003.32 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICE OF HEARINGS AND APPEALS PROCEDURAL REGULATIONS Appeals § 1003.32 What to file. A person filing under this subpart shall file an “Appeal of Order” which should be clearly...

  7. 76 FR 41790 - Natural Currents Energy Services, LLC; Notice of Intent To File License Application, Filing of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-15

    ... Energy Services, LLC; Notice of Intent To File License Application, Filing of Draft Application, Request for Waivers of Integrated Licensing Process Regulations Necessary for Expedited Processing of a.... Project No.: 12718-002. c. Date Filed: June 28, 2011. d. Submitted By: Natural Currents Energy Services...

  8. The Global File System

    NASA Technical Reports Server (NTRS)

    Soltis, Steven R.; Ruwart, Thomas M.; OKeefe, Matthew T.

    1996-01-01

    The global file system (GFS) is a prototype design for a distributed file system in which cluster nodes physically share storage devices connected via a network-like fiber channel. Networks and network-attached storage devices have advanced to a level of performance and extensibility so that the previous disadvantages of shared disk architectures are no longer valid. This shared storage architecture attempts to exploit the sophistication of storage device technologies whereas a server architecture diminishes a device's role to that of a simple component. GFS distributes the file system responsibilities across processing nodes, storage across the devices, and file system resources across the entire storage pool. GFS caches data on the storage devices instead of the main memories of the machines. Consistency is established by using a locking mechanism maintained by the storage devices to facilitate atomic read-modify-write operations. The locking mechanism is being prototyped in the Silicon Graphics IRIX operating system and is accessed using standard Unix commands and modules.

  9. 11 CFR 9006.2 - Filing dates.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 11 Federal Elections 1 2010-01-01 2010-01-01 false Filing dates. 9006.2 Section 9006.2 Federal Elections FEDERAL ELECTION COMMISSION PRESIDENTIAL ELECTION CAMPAIGN FUND: GENERAL ELECTION FINANCING REPORTS AND RECORDKEEPING § 9006.2 Filing dates. The reports required to be filed under 11 CFR 9006.1...

  10. 49 CFR 604.30 - Filing complaints.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., DEPARTMENT OF TRANSPORTATION CHARTER SERVICE Complaints § 604.30 Filing complaints. (a) Filing address. Unless provided otherwise, the complainant shall file the complaint with the Office of the Chief Counsel... Service Complaint docket number FTA-2007-0025 at http://www.regulations.gov or mail it to the docket by...

  11. 21 CFR 314.420 - Drug master files.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 5 2014-04-01 2014-04-01 false Drug master files. 314.420 Section 314.420 Food... master files. (a) A drug master file is a submission of information to the Food and Drug Administration by a person (the drug master file holder) who intends it to be used for one of the following purposes...

  12. 78 FR 20908 - Combined Notice of Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-08

    .... Description: UGI Storage Compliance Filing TL-96 to be effective 4/ 1/2013. Filed Date: 3/28/13. Accession... Eastern Pipe Line Company, LP. Description: Flow Through of Cash-Out Revenues filed on 3-28-13. Filed Date: 3/28/13. Accession Number: 20130328-5022. Comments Due: 5 p.m. ET 4/9/13. Docket Numbers: RP13-726...

  13. 12 CFR 19.10 - Filing of papers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 1 2011-01-01 2011-01-01 false Filing of papers. 19.10 Section 19.10 Banks and... Rules of Practice and Procedure § 19.10 Filing of papers. (a) Filing. Any papers required to be filed...) Delivering the papers to a reliable commercial courier service, overnight delivery service, or to the U.S...

  14. 12 CFR 19.10 - Filing of papers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Filing of papers. 19.10 Section 19.10 Banks and... Rules of Practice and Procedure § 19.10 Filing of papers. (a) Filing. Any papers required to be filed...) Delivering the papers to a reliable commercial courier service, overnight delivery service, or to the U.S...

  15. 12 CFR 747.10 - Filing of papers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Filing of papers. 747.10 Section 747.10 Banks... Practice and Procedure § 747.10 Filing of papers. (a) Filing. Any papers required to be filed, excluding...) Delivering the papers to a reliable commercial courier service, overnight delivery service, or to the U.S...

  16. 12 CFR 747.10 - Filing of papers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Filing of papers. 747.10 Section 747.10 Banks... Practice and Procedure § 747.10 Filing of papers. (a) Filing. Any papers required to be filed, excluding...) Delivering the papers to a reliable commercial courier service, overnight delivery service, or to the U.S...

  17. 29 CFR 24.103 - Filing of retaliation complaint.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... be reduced to writing by OSHA. If a complainant is not able to file the complaint in English, the complaint may be filed in any language. (c) Place of Filing. The complaint should be filed with the OSHA... resides or was employed, but may be filed with any OSHA officer or employee. Addresses and telephone...

  18. 75 FR 70733 - Combined Notice of Filings #1

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-18

    ... Corporation submits tariff filing per 35: 2010-10-29 CAISO MSG Transition Cost Compliance to be effective 11.... Description: Alcan Power Marketing, Inc. submits tariff filing per 35.12: Baseline Filing to be effective 11/1... Compliance Filing to be effective 9/30/2010. Filed Date: 10/29/2010. Accession Number: 20101029-5211. Comment...

  19. Robust keyword retrieval method for OCRed text

    NASA Astrophysics Data System (ADS)

    Fujii, Yusaku; Takebe, Hiroaki; Tanaka, Hiroshi; Hotta, Yoshinobu

    2011-01-01

    Document management systems have become important because of the growing popularity of electronic filing of documents and scanning of books, magazines, manuals, etc., through a scanner or a digital camera, for storage or reading on a PC or an electronic book. Text information acquired by optical character recognition (OCR) is usually added to the electronic documents for document retrieval. Since texts generated by OCR generally include character recognition errors, robust retrieval methods have been introduced to overcome this problem. In this paper, we propose a retrieval method that is robust against both character segmentation and recognition errors. In the proposed method, the insertion of noise characters and dropping of characters in the keyword retrieval enables robustness against character segmentation errors, and character substitution in the keyword of the recognition candidate for each character in OCR or any other character enables robustness against character recognition errors. The recall rate of the proposed method was 15% higher than that of the conventional method. However, the precision rate was 64% lower.

  20. 77 FR 34943 - Combined Notice of Filings #2

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-12

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Combined Notice of Filings 2 Take notice... Texas North Company submits tariff filing per 35.13(a)(2)(iii: TNC-Texas New Mexico Power Amd. 3 to IA... filing per 35.13(a)(2)(iii: Reactive Filing to be effective 12/31/9998. Filed Date: 6/5/12. Accession...