Sample records for tadeusz gil jacek

  1. Tadeusz Banachiewicz in Tartu (1915 to 1918)

    NASA Astrophysics Data System (ADS)

    Flin, P.; Panko, E.

    Tadeusz Banachiewicz (1882--1954) was an outstanding Polish astro\\-nomer, mathematician and geodesist. He was a professor at the Jagiellonian University in Cracow and director of the Astronomical Observatory (1919--1954), and had a strong influence on Polish astronomy. His achievements led to honorary degrees at universities, fellowships in academies of sciences, and the prestige of high positions in international organizations, such as the International Astronomical Union and the Baltic Geodetic Commission. He is known from both his theoretical and observational studies, his famous motto being: ``observo ergo sum''. Here we recall three years of his activity in Tartu, where Tadeusz Banachiewicz made the most important steps in his career. He arrived at Yuryev in October of 1915, employed as a young assistant. In March 1918 he became the extraordinary professor and director of the Astronomical Observatory.

  2. The Government Information Locator Service (GILS)

    USGS Publications Warehouse

    Christian, E.

    1996-01-01

    In coordination with the Information Infrastructure Task Force (IITF), the Office of Management and Budget (OMB) is promoting the establishment of an agency-based Government Information Locator Service (GILS) to help the public locate and access information throughout the Federal Government. This report presents a vision of how GILS will be implemented. Working primarily with OMB and the Locator Subgroup of the Interagency Working Group on Public Access, Eliot Christian of the US Geological Survey prepared this report under the auspices of the IITF Committee on Information Policy. This vision of GILS has also received extensive review by various Federal agencies and other interested parties, including some non-Federal organizations and by the general public through notices in both the Federal Register and the Commerce Business Daily and at a public meeting held in December, 1993. As part of the Federal role in the National Information Infrastructure, GILS will identify and describe information resources throughout the Federal government, and provide assistance in obtaining the information. It will be decentralized and will supplement other agency and commercial information dissemination mechanisms. The public will use GILS directly or through intermediaries, such as the Government Printing Office, the National Technical Information Service, the Federal depository libraries, other public libraries, and private sector information services. Direct users will have access to a GILS Core accessible on the Internet without charge. Intermediate access may include kiosks, "800 numbers", electronic mail, bulletin boards, fax, and off-line media such as floppy disks, CD-ROM, and printed works. GILS will use standard network technology and the American National Standards Institute Z39.50 standard for information search and retrieval so that information can be retrieved in a variety of ways. Direct users will eventually have access to many other Federal and non

  3. Immunosuppressive therapy in glomerular diseases: major accomplishment of Tadeusz Orłowski and his school.

    PubMed

    Smogorzewski, Mirosław J; Lao, Mieczysław; Gradowska, Liliana; Rowińska, Danuta; Rancewicz, Zofia

    2009-05-01

    Glomerulopathies are the third most common cause of end-stage renal failure. Immunosuppressive treatment of glomerulonephritis in a systematic way was introduced in Poland by Professor Tadeusz Orłowski in the early 1960s. The studies were conducted at the First Department of Medicine and at the Transplantation Institute of the Medical Academy in Warsaw in the years 1962-1988. This paper critically reviews the results of studies on the use of combined, triple-drug (prednisone/chlorambucil/azathioprine), immunosuppressive protocol in various pathological forms of glomerulopathies. We conclude that immunosuppressive protocols pioneered by Tadeusz Orłowski continue to be the backbone of the treatment of glomerulonephritis, especially the one with nephrotic syndrome, progressive impairment of kidney function and poor prognosis.

  4. Smart information system for gachon university gil hospital.

    PubMed

    Park, Dong Kyun; Jung, Eun Young; Jeong, Byung Hui; Moon, Byung Chan; Kang, Hyung Wook; Tchah, Hann; Han, Gi Seong; Cheng, Woo Sung; Lee, Young Ho

    2012-03-01

    In this research, the hospital information system of Gachon University Gil hospital is introduced and a future strategy for hospital information systems is proposed. This research introduces the development conditions of hospital information system at Gachon University Gil hospital, information about the development of the enterprise resource planning (ERP), a medical service process improvement system, and the personal health record (PHR) system. The medical service process and work efficiency were improved through the medical service process improvement system, which is the most common hospital information system at Gachon University Gil hospital and which includes an emergency medical service system, an online evaluation system and a round support system. Gachon University Gil hospital developed medical service improvement systems to increase work efficiency of medical team and optimized the systems to prove the availability of high-quality medical services for patients and their families. The PHR-based personalized health care solution is under development and will provide higher quality medical service for more patients in the future.

  5. Smart Information System for Gachon University Gil Hospital

    PubMed Central

    Jung, Eun Young; Jeong, Byung Hui; Moon, Byung Chan; Kang, Hyung Wook; Tchah, Hann; Han, Gi Seong; Cheng, Woo Sung; Lee, Young Ho

    2012-01-01

    Objectives In this research, the hospital information system of Gachon University Gil hospital is introduced and a future strategy for hospital information systems is proposed. Methods This research introduces the development conditions of hospital information system at Gachon University Gil hospital, information about the development of the enterprise resource planning (ERP), a medical service process improvement system, and the personal health record (PHR) system. Results The medical service process and work efficiency were improved through the medical service process improvement system, which is the most common hospital information system at Gachon University Gil hospital and which includes an emergency medical service system, an online evaluation system and a round support system. Conclusions Gachon University Gil hospital developed medical service improvement systems to increase work efficiency of medical team and optimized the systems to prove the availability of high-quality medical services for patients and their families. The PHR-based personalized health care solution is under development and will provide higher quality medical service for more patients in the future. PMID:22509476

  6. Z39.50 and GILS model. [Government Information Locator Service

    NASA Technical Reports Server (NTRS)

    Christian, Eliot

    1994-01-01

    The Government Information Locator System (GILS) is a component of the National Information Infrastructure (NII) which provides electronic access to sources of publicly accessible information maintained throughout the Federal Government. GILS is an internetworking information resource that identifies other information resources, describes the information available in the referenced resources, and provides assistance in how to obtain the information either directly or through intermediaries. The GILS core content which references each Federal information system holding publicly accessible data or information is described in terms of mandatory and optional core elements.

  7. Remembrance of professor Tadeusz Marciniak - Lviv tradition in Wrocław.

    PubMed

    Kacała, Ryszard R; Woźniak, Sławomir; Porwolik, Michał; Dąbrowski, Paweł; Domagała, Zygmunt; Kacała, Arkadiusz; Gworys, Bohdan

    2015-01-01

    After the seizure of Lviv by the Soviets, in the years 1944-1946, Tadeusz Marciniak worked in the Descriptive Anatomy Department in the State-Medical Institute of Lviv and also performed the function of the dean of the Medical Faculty. On receiving a proposal to assume the Chair of the Anatomy Department in Wrocław, he made the decision to leave Lviv. By July 2nd, 1946, prof. Tadeusz Marciniak had taken over the duties of full professor of the Descriptive Anatomy Department of the Medical Faculty of the University and the Technical College of Wrocław. On taking his job in Wrocław, prof. Marciniak undertook attempts to restore the worn out parts of the Anatomy Department building. Due to the lack of Polish manuals, he also took to the preparation of scripts for medical students. Professor Marciniak was a member of the Wrocław Section of the Polish Anthropological Association and a regular member of the Wroclaw Association of Science. His main scientific interests referred to the morphogenesis of the central nervous system and urinary system. He concentrated on circulatory system and muscular system tetralogies. Professor Marciniak also actively participated in administrative work at the university. In the years 1947-1948, he held the office of associate dean of the Medical Faculty, and till 1950 was a member of the Senate of the University and Technical College of Wrocław. In the years 1959-1962, he was a vice rector of the Medical University of Wrocław.

  8. Helping the public find information the U.S. Government Information Locator Service (GILS)

    USGS Publications Warehouse

    Christian, E.J.

    1994-01-01

    As part of the National Information Infrastructure, the U.S. federal government is establishing a Government Information Locator Service (GILS). GILS will identify and describe public information resources throughout the federal government and provide assistance in obtaining the information. It will be decentralized and will supplement other agency and commercial information dissemination mechanisms. The public will use GILS directly or through intermediaries, including the Government Printing Office and the National Technical Information Service, as well as federal depository libraries, other public libraries, and private sector information services. Direct users will have access to a GILS Core accessible on the Internet without charge. Intermediate access may include kiosks, 800 numbers, electronic mail, bulletin boards, FAX, and offline media such as floppy disks, CD-ROM, and printed works. GILS will use network technology and the American National Standards Institute Z39.50 standard for information search and retrieval so that information can be retrieved in a variety of ways. Direct users may have access to many other major federal and nonfederal information resources, linkages to data systems, and electronic delivery of information products. An Office of Management and Budget Bulletin in 1994 will provide implementing guidance to agencies. The National Institute of Standards and Technology will also establish a Federal Information Processing Standard specifying a GILS Profile and its application for agencies establishing information locators. ?? 1994.

  9. Government Information Locator Service (GILS). Draft report to the Information Infrastructure Task Force

    NASA Technical Reports Server (NTRS)

    1994-01-01

    This is a draft report on the Government Information Locator Service (GILS) to the National Information Infrastructure (NII) task force. GILS is designed to take advantage of internetworking technology known as client-server architecture which allows information to be distributed among multiple independent information servers. Two appendices are provided -- (1) A glossary of related terminology and (2) extracts from a draft GILS profile for the use of the American National Standard Information Retrieval Application Service Definition and Protocol Specification for Library Applications.

  10. Integrating Play in Family Therapy: An Interview with Eliana Gil, Ph.D.

    ERIC Educational Resources Information Center

    Christensen, Teresa M.; Thorngren, Jill M.

    2000-01-01

    Presents an interview with Eliana Gil, the current director of the Starbright Training Institute for child abuse and neglect, play therapy, and family play therapy in Springfield, Virginia. Gil's publications and experiences have spoken to coconstructing family therapy sessions that effectively integrate the paradigms of play and family therapy.…

  11. Chromosome-encoded narrow-spectrum Ambler class A beta-lactamase GIL-1 from Citrobacter gillenii.

    PubMed

    Naas, Thierry; Aubert, Daniel; Ozcan, Ayla; Nordmann, Patrice

    2007-04-01

    A novel beta-lactamase gene was cloned from the whole-cell DNA of an enterobacterial Citrobacter gillenii reference strain that displayed a weak narrow-spectrum beta-lactam-resistant phenotype and was expressed in Escherichia coli. It encoded a clavulanic acid-inhibited Ambler class A beta-lactamase, GIL-1, with a pI value of 7.5 and a molecular mass of ca. 29 kDa. GIL-1 had the highest percent amino acid sequence identity with TEM-1 and SHV-1, 77%, and 67%, respectively, and only 46%, 31%, and 32% amino acid sequence identity with CKO-1 (C. koseri), CdiA1 (C. diversus), and SED-1 (C. sedlaki), respectively. The substrate profile of the purified GIL-1 was similar to that of beta-lactamases TEM-1 and SHV-1. The blaGIL-1 gene was chromosomally located, as revealed by I-CeuI experiments, and was constitutively expressed at a low level in C. gillenii. No gene homologous to the regulatory ampR genes of chromosomal class C beta-lactamases was found upstream of the blaGIL-1 gene, which fits the noninducibility of beta-lactamase expression in C. gillenii. Rapid amplification of DNA 5' ends analysis of the promoter region revealed putative promoter sequences that diverge from what has been identified as the consensus sequence in E. coli. The blaGIL-1 gene was part of a 5.5-kb DNA fragment bracketed by a 9-bp duplication and inserted between the d-lactate dehydrogenase gene and the ydbH genes; this DNA fragment was absent in other Citrobacter species. This work further illustrates the heterogeneity of beta-lactamases in Citrobacter spp., which may indicate that the variability of Citrobacter species is greater than expected.

  12. Phytochrome-mediated agravitropism in Arabidopsis hypocotyls requires GIL1 and confers a fitness advantage.

    PubMed

    Allen, Trudie; Ingles, Patricia J; Praekelt, Uta; Smith, Harry; Whitelam, Garry C

    2006-05-01

    Plants use specialized photoreceptors to detect the amount, quality, periodicity and direction of light and to modulate their growth and development accordingly. These regulatory light signals often interact with other environmental cues. Exposure of etiolated Arabidopsis seedlings to red (R) or far-red (FR) light causes hypocotyls to grow in random orientations with respect to the gravitational vector, thus overcoming the signal from gravity to grow upwards. This light response, mediated by either phytochrome A or phytochrome B, represents a prime example of cross-talk between environmental signalling systems. Here, we report the isolation the mutant gil1 (for gravitropic in the light) in which hypocotyls continue to grow upwards after exposure of seedlings to R or FR light. The gil1 mutant displays no other phenotypic alterations in response to gravity or light. Cloning of GIL1 has identified a novel gene that is necessary for light-dependent randomization of hypocotyl growth orientation. Using gil1, we have demonstrated that phytochrome-mediated randomization of Arabidopsis hypocotyl orientation provides a fitness advantage to seedlings developing in patchy, low-light environments.

  13. The Crystal Structure and Mechanism of an Unusual Oxidoreductase, GilR, Involved in Gilvocarcin V Biosynthesis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Noinaj, Nicholas; Bosserman, Mary A.; Schickli, M. Alexandra

    2012-11-26

    GilR is a recently identified oxidoreductase that catalyzes the terminal step of gilvocarcin V biosynthesis and is a unique enzyme that establishes the lactone core of the polyketide-derived gilvocarcin chromophore. Gilvocarcin-type compounds form a small distinct family of anticancer agents that are involved in both photo-activated DNA-alkylation and histone H3 cross-linking. High resolution crystal structures of apoGilR and GilR in complex with its substrate pregilvocarcin V reveals that GilR belongs to the small group of a relatively new type of the vanillyl-alcohol oxidase flavoprotein family characterized by bicovalently tethered cofactors. GilR was found as a dimer, with the bicovalently attachedmore » FAD cofactor mediated through His-65 and Cys-125. Subsequent mutagenesis and functional assays indicate that Tyr-445 may be involved in reaction catalysis and in mediating the covalent attachment of FAD, whereas Tyr-448 serves as an essential residue initiating the catalysis by swinging away from the active site to accommodate binding of the 6R-configured substrate and consequently abstracting the proton of the hydroxyl residue of the substrate hemiacetal 6-OH group. These studies lay the groundwork for future enzyme engineering to broaden the substrate specificity of this bottleneck enzyme of the gilvocarcin biosynthetic pathway for the development of novel anti-cancer therapeutics.« less

  14. The crystal structure and mechanism of an unusual oxidoreductase, GilR, involved in gilvocarcin V biosynthesis.

    PubMed

    Noinaj, Nicholas; Bosserman, Mary A; Schickli, M Alexandra; Piszczek, Grzegorz; Kharel, Madan K; Pahari, Pallab; Buchanan, Susan K; Rohr, Jürgen

    2011-07-01

    GilR is a recently identified oxidoreductase that catalyzes the terminal step of gilvocarcin V biosynthesis and is a unique enzyme that establishes the lactone core of the polyketide-derived gilvocarcin chromophore. Gilvocarcin-type compounds form a small distinct family of anticancer agents that are involved in both photo-activated DNA-alkylation and histone H3 cross-linking. High resolution crystal structures of apoGilR and GilR in complex with its substrate pregilvocarcin V reveals that GilR belongs to the small group of a relatively new type of the vanillyl-alcohol oxidase flavoprotein family characterized by bicovalently tethered cofactors. GilR was found as a dimer, with the bicovalently attached FAD cofactor mediated through His-65 and Cys-125. Subsequent mutagenesis and functional assays indicate that Tyr-445 may be involved in reaction catalysis and in mediating the covalent attachment of FAD, whereas Tyr-448 serves as an essential residue initiating the catalysis by swinging away from the active site to accommodate binding of the 6R-configured substrate and consequently abstracting the proton of the hydroxyl residue of the substrate hemiacetal 6-OH group. These studies lay the groundwork for future enzyme engineering to broaden the substrate specificity of this bottleneck enzyme of the gilvocarcin biosynthetic pathway for the development of novel anti-cancer therapeutics.

  15. [The medical world of Juan Gil de Zamora's Historia Naturalis (ca. 1275-1296)].

    PubMed

    García Ballester, L; Domínguez, A

    1994-01-01

    The article describes the authors and works which were quoted by the Franciscan Juan Gil de Zamora in his Historia naturalis, a scientific encyclopaedia written between c. 1275 and before 1296, probably in the Franciscan monastery of Zamora (Kingdom of Castille). Juan Gil made wide use of the Avicenna's Canon, Gilbertus de Aquila (Anglicus)'s Compendium medicine, and Salernitan medical literature. His work contributed to the diffusion of these medical authors and works throughout the Christian intellectual milieu of late medieval Castille. This diffusion was not without problems.

  16. XDS-I Gateway Development for HIE Connectivity with Legacy PACS at Gil Hospital.

    PubMed

    Simalango, Mikael Fernandus; Kim, Youngchul; Seo, Young Tae; Choi, Young Hwan; Cho, Yong Kyun

    2013-12-01

    The ability to support healthcare document sharing is imperative in a health information exchange (HIE). Sharing imaging documents or images, however, can be challenging, especially when they are stored in a picture archiving and communication system (PACS) archive that does not support document sharing via standard HIE protocols. This research proposes a standard-compliant imaging gateway that enables connectivity between a legacy PACS and the entire HIE. Investigation of the PACS solutions used at Gil Hospital was conducted. An imaging gateway application was then developed using a Java technology stack. Imaging document sharing capability enabled by the gateway was tested by integrating it into Gil Hospital's order communication system and its HIE infrastructure. The gateway can acquire radiology images from a PACS storage system, provide and register the images to Gil Hospital's HIE for document sharing purposes, and make the images retrievable by a cross-enterprise document sharing document viewer. Development of an imaging gateway that mediates communication between a PACS and an HIE can be considered a viable option when the PACS does not support the standard protocol for cross-enterprise document sharing for imaging. Furthermore, the availability of common HIE standards expedites the development and integration of the imaging gateway with an HIE.

  17. XDS-I Gateway Development for HIE Connectivity with Legacy PACS at Gil Hospital

    PubMed Central

    Simalango, Mikael Fernandus; Kim, Youngchul; Seo, Young Tae; Cho, Yong Kyun

    2013-01-01

    Objectives The ability to support healthcare document sharing is imperative in a health information exchange (HIE). Sharing imaging documents or images, however, can be challenging, especially when they are stored in a picture archiving and communication system (PACS) archive that does not support document sharing via standard HIE protocols. This research proposes a standard-compliant imaging gateway that enables connectivity between a legacy PACS and the entire HIE. Methods Investigation of the PACS solutions used at Gil Hospital was conducted. An imaging gateway application was then developed using a Java technology stack. Imaging document sharing capability enabled by the gateway was tested by integrating it into Gil Hospital's order communication system and its HIE infrastructure. Results The gateway can acquire radiology images from a PACS storage system, provide and register the images to Gil Hospital's HIE for document sharing purposes, and make the images retrievable by a cross-enterprise document sharing document viewer. Conclusions Development of an imaging gateway that mediates communication between a PACS and an HIE can be considered a viable option when the PACS does not support the standard protocol for cross-enterprise document sharing for imaging. Furthermore, the availability of common HIE standards expedites the development and integration of the imaging gateway with an HIE. PMID:24523994

  18. [What is thinking inside the individual? Figurations of Collectivity in Ludwik Fleck, Tadeusz Bilikiewicz, and Ludwig Gumplowicz].

    PubMed

    Johach, Eva

    2014-01-01

    "What thinks in man, is not he himself, but his social community." These words by the early sociologist Ludwig Gumplowicz (1838–1909) were quoted several times by Ludwik Fleck (1896–1961) and seem to be in complete agreement with his own theory of thought collectives. The assumption that even scientific ideas were not so much generated by the scientist as an autonomous individual but rather by and within the social environment was still considered provocative by Fleck in the 1930s. This article will explore the implications of this assumption by comparing Fleck with Gumplowicz as well as with Tadeusz Bilikiewicz (1901–1980), a psychiatrist, philosopher and historian of medicine working like Fleck in the cultural milieu of Lwów/Lemberg.

  19. [Tadeusz Tucholski (1898-1940). A contribution to the scientific biography].

    PubMed

    Tucholska-Załuska, Hanna

    2014-01-01

    Assistant professor Tadeusz Tucholski Ph.D., murdered in Katyń, was one of the most outstanding representatives of the younger generation of Polish physical chemist scholars of the interwar period. He published over 30 scientific papers in the field of physical and chemical properties of explosions, kinetics and catalysis and also toxicology and forensics. Thesere searches were partly performed at the University of Poznań, in the period 1926-1939, at the Faculty of Medicine of the Department of Physics where Tucholski was employed as a senior assistant and was the closest associate of professor S. Kalandyk, partly at the Department of Forensic Medicine headed by professor S. Horoszkiewicz in the chemical-toxicological laboratory which Tucholski ranin the years 1931-1939, partly at the Warsaw University of Technology in the Department of Explosives Technology of the Faculty of Chemistry headed by professor T. Urbański, where he had been lecturing "On the latest theories of explosives" since 1937 and in 1934-35 in Cambridge, as a teaching fellow of the National Culture Fund, in Colloid Science Laboratory headed by professor E.K. Rideal. In 1903 Tucholski moved with his parents to Zabaykalye, in 1911--to Brazil. He returned to Poland in 1920, joined the Polish Army and with the 14th Polish Medium Regiment fought on the fronts of the Polish-Bolshevik War. He was drafted to the School of Pyrotechnics Foremen at Corps District Command number VII (Poznań). After graduating, Tucholski remained on active duty as a professional pyrotechnic: from 1921 to 1929 he was appointed the head of the Laboratory of Chemical and Pyrotechnic Ammunition Workshop No. 2 in Poznań and as an inspector of magazines of explosives. In 1927 he was transferred to the reserves, in 1932 after having graduated from the Officer Cadet School in Jarocin, Tucholski was appointed a second lieutenant in the Army Reserve, and later moved from the officers infantry corpsto the army ordnance corps. As

  20. [Exploration of salt in Poland in the second half of the 18th century].

    PubMed

    Danowska, Ewa

    2014-01-01

    Following the First Partition in 1772, Poland lost the salt mines in Wieliczka, Bochnia and in the territory of Ruthenia to Austria. This was a serious blow to the economy, because since then, it became necessary to import salt, which was primarily taken advantage of by the Royal Prussian Maritime Trading Company (Pruska Kompania Morska) importing it from Austria. King Stanislaw August Poniatowski tried to initiate the exploration and exploitation of salt in the areas where it could be profitable. To this end, he ordered the exploration to Filip Carosi and Stanislaw Okraszewski, among other. The salt-works of the Castellan of Leukow, Jacek Jezierski in the town of Solca, in the Lqczyckie Region, active since 1780, was a private investment. Leopold von Beust's Kompania akcyjna obtained salt from a brine near the town of Busko, and Kompania z Osob Krajowych--from a brine in the town of Raczki nad Pilica. In 1782, the King appointed The Ore Commission (Komisja Kruszcowa), consisted of twelve commissioners, in order to conduct the exploration for minerals, including salt, their extraction and further administration. The Crown Treasury Commission (Komisja Skarbu Koronnego), a magistracy dealing with, among others, the economy of the country in a broad sense, was also involved in the exploration and exploatation of salt. At its command, in the summer of 1788, Tadeusz Czacki made a tour of the Kielce region in search of traces of salt. In view of the important events of the Four-Year Sejm (Sejm Czteroletni) and the subsequent loss of independence, the subject of salt exploration had to be abandoned.

  1. JPRS Report, East Europe.

    DTIC Science & Technology

    1988-04-12

    the Polish Army Main Political Board [ GZP WP], Gen Tadeusz Szacilo, participated in the briefing. On the first day of the conference—Vice Admiral...Lud- wik Dutkowski, first deputy chief of the GZP WP, participated—participants heard many interesting JPRS-EER-88-030 12 April 1988...in these areas were presented by deputy chief of the GZP WP Brig Gen Tadeusz Kojder and Brig Gen Dr Leslaw Wojtasik. Much attention was devoted to

  2. A metadata initiative for global information discovery

    USGS Publications Warehouse

    Christian, E.

    2001-01-01

    The Global Information Locator Service (GILS) encompasses a global vision framed by the fundamental values of open societies. Societal values such as a free flow of information impose certain requirements on the society's information infrastructure. These requirements in turn shape the various laws, policies, standards, and technologies that determine the infrastructure design. A particular focus of GILS is the requirement to provide the means for people to discover sources of data and information. Information discovery in the GILS vision is designed to be decentralized yet coherent, and globally comprehensive yet useful for detailed data. This article introduces basic concepts and design issues, with emphasis on the techniques by which GILS supports interoperability. It explains the practical implications of GILS for the common roles of organizations involved in handling information, from content provider through system engineer and intermediary to searcher. The article provides examples of GILS initiatives in various types of communities: bibliographic, geographic, environmental, and government. ?? 2001 Elsevier Science Inc.

  3. Conference Proceedings for Optical Fiber Sensors Conference (8th) held in Monterey, California on January 29 - 31 1992

    DTIC Science & Technology

    1992-01-01

    Research Center, East Hartford, CT Program Chair Anthony Dandridge Naval Research Laboratory, Washington, DC PROGRAM COMMnrTEE KIIIl BIetekjaer WAilliam W...Moray Norwegian knst. of Technology, Norway tkited Technologies Research Center, East Hartford, CT Jacek Chrostowski Julchl Noda National Research ...Technology, Boulder, CO Aa .Rgr Shacul Ezekiel *Vngs College, London, United lingdomn MIT, Lexington, MA Pee J. Samson Masamltsu Haruna BHP Central Research

  4. Guidance for Selecting Legitimate Recycling Products and Processes

    DTIC Science & Technology

    1998-10-23

    information you have provided on the GIL glassification process for electric arc furnace ( EAF ) dust or K061 when the EAF dust is a hazardous waste. Based on the...regarding the regulatory status of the GIL process and glass frit product has been whether EAF dust incorporated into GIL glass frit meets the definition...emission control dust from a primary copper smelter could be returned to any part of the process associated with copper production. The material also cannot

  5. Hardware-in-the-Loop Co-simulation of Distribution Grid for Demand Response

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rotger-Griful, Sergi; Chatzivasileiadis, Spyros; Jacobsen, Rune H.

    2016-06-20

    In modern power systems, co-simulation is proposed as an enabler for analyzing the interactions between disparate systems. This paper introduces the co-simulation platform Virtual Grid Integration Laboratory (VirGIL) including Hardware-in-the-Loop testing, and demonstrates its potential to assess demand response strategies. VirGIL is based on a modular architecture using the Functional Mock-up Interface industrial standard to integrate new simulators. VirGIL combines state-of-the-art simulators in power systems, communications, buildings, and control. In this work, VirGIL is extended with a Hardware-in-the-Loop component to control the ventilation system of a real 12-story building in Denmark. VirGIL capabilities are illustrated in three scenarios: load following,more » primary reserves and load following aggregation. Experimental results show that the system can track one minute changing signals and it can provide primary reserves for up-regulation. Furthermore, the potential of aggregating several ventilation systems is evaluated considering the impact at distribution grid level and the communications protocol effect.« less

  6. The German Interlinguistics Society Gesellschaft fur Interlinguistik.

    ERIC Educational Resources Information Center

    O Riain, Sean

    2003-01-01

    Describes the German interlinguistics society Gesellschaft fur Interlinguistik (GIL), which was founded to bring together interlinguistics and esperantology scholars. Highlights GIL's principal fields of activity and discusses its role in the fields of international linguistic communication, language planning, esperantolgy, and the teaching of…

  7. Teaching Gil to Lead

    ERIC Educational Resources Information Center

    Davis, Stephen H.; Leon, Ronald J.

    2009-01-01

    The complexities of public education today require new, distributed models of school leadership in which teachers play a central role. The most effective teachers assume leadership roles as instructors and professional colleagues. In this article, we propose a framework for developing teacher leadership that consists of four intersecting domains:…

  8. Suggested Geographic Information Literacy for K-12

    ERIC Educational Resources Information Center

    Miller, Jason; Keller, C. Peter; Yore, Larry D.

    2005-01-01

    Geographic information literacy (GIL) is defined as the possession of concepts, abilities and habits of mind that allow an individual to understand and use geographic information properly. This paper reports the results of an online survey undertaken to get expert input into specifying the concepts and abilities associated with GIL that should be…

  9. Translations on Eastern Europe, Scientific Affairs, Number 592.

    DTIC Science & Technology

    1978-07-13

    Period Covered 14. 15. Supplementary Notes 16. Abstracts The serial report contains articles concerning the development of and progress in the...Personnel (NAUKA POLSKA, Mar-Apr 78) 6 ROMANIA New Herbicide To Protect Trifolium Crops (N. Sarpe; AGRICULTURA SOCIALISTA, 13 May 78) 17...Organs," and PAN Member Tadeusz Ruebenbauer: " Rye and Possibilities for Improving It." The following persons presented lectures in exact and

  10. JPRS Report, East Europe.

    DTIC Science & Technology

    1991-02-05

    passage omitted] Polish Television has broadcast an interview with Prof Z. Brzezinski , former advisor to President Carter for national security. He...intervention with Brezhnev was supposed to lead to the abandonment of the invasion. Brzezinski thinks that the new president should give Kuklinski "a high...member presidium: chairman, Tadeusz Mazowiecki; secretary, Piotr Nowina-Konopka. Wla- dyslaw Frasyniuk and Henryk Wujec were designated by Citizens

  11. East Europe Report.

    DTIC Science & Technology

    1987-02-05

    difficulties in order to finish on schedule and not to slow down the work tempo. The director of the coking plant under construction, Dr Engineer Piotr Dybala...Wlodzimierz Szewczynski, Stanislaw Janiak, Franciszek Piecuch, and Janusz Wieczorkiewicz . At the end of the meeting, General Tadeusz Szacilo, head of...have to be filled out and read turns activists into chairwarmers. Piotr Dziewit, POP secretary at the Koszarawa Gmina Office, reminisces, "I remember

  12. A model for self-diffusion of guanidinium-based ionic liquids: a molecular simulation study.

    PubMed

    Klähn, Marco; Seduraman, Abirami; Wu, Ping

    2008-11-06

    We propose a novel self-diffusion model for ionic liquids on an atomic level of detail. The model is derived from molecular dynamics simulations of guanidinium-based ionic liquids (GILs) as a model case. The simulations are based on an empirical molecular mechanical force field, which has been developed in our preceding work, and it relies on the charge distribution in the actual liquid. The simulated GILs consist of acyclic and cyclic cations that were paired with nitrate and perchlorate anions. Self-diffusion coefficients are calculated at different temperatures from which diffusive activation energies between 32-40 kJ/mol are derived. Vaporization enthalpies between 174-212 kJ/mol are calculated, and their strong connection with diffusive activation energies is demonstrated. An observed formation of cavities in GILs of up to 6.5% of the total volume does not facilitate self-diffusion. Instead, the diffusion of ions is found to be determined primarily by interactions with their immediate environment via electrostatic attraction between cation hydrogen and anion oxygen atoms. The calculated average time between single diffusive transitions varies between 58-107 ps and determines the speed of diffusion, in contrast to diffusive displacement distances, which were found to be similar in all simulated GILs. All simulations indicate that ions diffuse by using a brachiation type of movement: a diffusive transition is initiated by cleaving close contacts to a coordinated counterion, after which the ion diffuses only about 2 A until new close contacts are formed with another counterion in its vicinity. The proposed diffusion model links all calculated energetic and dynamic properties of GILs consistently and explains their molecular origin. The validity of the model is confirmed by providing an explanation for the variation of measured ratios of self-diffusion coefficients of cations and paired anions over a wide range of values, encompassing various ionic liquid classes

  13. Ionic Liquid Fuels for Chemical Propulsion

    DTIC Science & Technology

    2016-10-31

    nucleophilicity in the ionic liquid is critical. Both gas -phase and condensed-phase (CPCM-GIL) density functional theory calculations support the...stability trends in dialkylimidazolium ionic liquids and could be used as a higher accuracy method than the gas -phase DFT approach for predicting thermal...stabilities of ionic liquids in general. One important finding from the comparison of the gas -phase basicities relative to the GIL condensed- phase

  14. Interoperability and information discovery

    USGS Publications Warehouse

    Christian, E.

    2001-01-01

    In the context of information systems, there is interoperability when the distinctions between separate information systems are not a barrier to accomplishing a task that spans those systems. Interoperability so defined implies that there are commonalities among the systems involved and that one can exploit such commonalities to achieve interoperability. The challenge of a particular interoperability task is to identify relevant commonalities among the systems involved and to devise mechanisms that exploit those commonalities. The present paper focuses on the particular interoperability task of information discovery. The Global Information Locator Service (GILS) is described as a policy, standards, and technology framework for addressing interoperable information discovery on a global and long-term basis. While there are many mechanisms for people to discover and use all manner of data and information resources, GILS initiatives exploit certain key commonalities that seem to be sufficient to realize useful information discovery interoperability at a global, long-term scale. This paper describes ten of the specific commonalities that are key to GILS initiatives. It presents some of the practical implications for organizations in various roles: content provider, system engineer, intermediary, and searcher. The paper also provides examples of interoperable information discovery as deployed using GILS in four types of information communities: bibliographic, geographic, environmental, and government.

  15. Translations on Narcotics and Dangerous Drugs, Number 317

    DTIC Science & Technology

    1977-08-31

    bank robberies - Bamerindus, Rua da Quitanda branch, where 4 million cruzeiros were stolen; Banco do Brazil in Guadalupe, 800,000 cruzeiros, and...which broke out between mafia groups claimed a new victim yesterday when known trafficker Mario Gil Ramirez was slain. This criminal, against whom...persons while he was talking with his wife and other individuals in the "El Canecao" [The Tankard] bar. Gil Ramirez had been involved in several

  16. Translations on Narcotics and Dangerous Drugs No. 298

    DTIC Science & Technology

    1977-05-06

    Cabecao was arrested, and detectives Dagomar Ruas Silva and Vitor Alves da Mota, both of whom were working at the time at the now-closed Vigilancia-Norte...Carvajal. It is believed that Mario Gil Ramirez , husband of Bercey Espinosa de Gil, and Miguel Alberto Lopez, who was recently arrested by F-2, are...clandestine laboratory in that city. Arrested were Segundo Gonzaga Granda, Ocamidoro Gonzaga Diaz and Epaminondas Ramirez Acosta. The traffickers were

  17. Science and Technology for the Future Force. FY2006 Summer Study

    DTIC Science & Technology

    2007-03-01

    Panel Members Co-Chairs • Allen Adler • Gil Herrera • Charley Otstott Staff Assistant • Oscar Valent, ASA(ALT) Government Advisors • LTC(P) Keith Edwards...measures to cross- train/ educate personnel Transitioning Technology is a Contact Sport Technology transition from the S&T community to the acquisition...Members Co-Chairs • Allen Adler • Gil Herrera • Charley Otstott Staff Assistant • Oscar Valent, ASA(ALT) Government Advisors • LTC(P) Keith Edwards, ARCIC

  18. Structural basis for clonal diversity of the human T-cell response to a dominant influenza virus epitope

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yang, Xinbo; Chen, Guobing; Weng, Nan-ping

    Influenza A virus (IAV) causes an acute infection in humans that is normally eliminated by CD8+ cytotoxic T lymphocytes. Individuals expressing the MHC class I molecule HLA-A2 produce cytotoxic T lymphocytes bearing T-cell receptors (TCRs) that recognize the immunodominant IAV epitope GILGFVFTL (GIL). Most GIL-specific TCRs utilize α/β chain pairs encoded by the TRAV27/TRBV19 gene combination to recognize this relatively featureless peptide epitope (canonical TCRs). However, ~40% of GIL-specific TCRs express a wide variety of other TRAV/TRBV combinations (non-canonical TCRs). To investigate the structural underpinnings of this remarkable diversity, we determined the crystal structure of a non-canonical GIL-specific TCR (F50)more » expressing the TRAV13-1/TRBV27 gene combination bound to GIL–HLA-A2 to 1.7 Å resolution. Comparison of the F50–GIL–HLA-A2 complex with the previously published complex formed by a canonical TCR (JM22) revealed that F50 and JM22 engage GIL–HLA-A2 in markedly different orientations. These orientations are distinguished by crossing angles of TCR to peptide–MHC of 29° for F50 versus 69° for JM22 and by a focus by F50 on the C terminus rather than the center of the MHC α1 helix for JM22. In addition, F50, unlike JM22, uses a tryptophan instead of an arginine to fill a critical notch between GIL and the HLA-A2 α2 helix. The F50–GIL–HLA-A2 complex shows that there are multiple structurally distinct solutions to recognizing an identical peptide–MHC ligand with sufficient affinity to elicit a broad anti-IAV response that protects against viral escape and T-cell clonal loss.« less

  19. Ecological Risk Assessment of Perchlorate in Avian Species, Rodents, Amphibians and Fish

    DTIC Science & Technology

    2003-04-01

    http://www .indiana.edu/- axolotl ). 10.0 JUSTIFICATION OF TEST SYSTEM Perchlorate occurs in ground and surface waters in 44 states in the USA... axolotl ). * Sequentially numbered in order of the date that the change is effective Dept. of Biological Sciences (DBS) Box 43131 Lubbock, TX 79409...KCl, 0.025 giL; CaCh2 H20, 0.65 g/L; MgS04·7H20, 0.1 giL (http://www.indiana.edu/~ axolotl ). *Sequentially numbered in order of the date that the

  20. Surgical treatment of GERD. Comperative study of WTP vs. Toupet fundoplication - results of 151 consecutive cases.

    PubMed

    Wróblewski, Tadeusz; Kobryn, Konrad; Nowosad, Małgorzata; Krawczyk, Marek

    2016-01-01

    Gastroesophageal reflux disease (GERD) is recognized as one of the most common disorders of the upper gastrointestinal tract (GIT). The best choice of management for advanced GERD is laparoscopic surgery. To compare and evaluate the results of surgical treatment of GERD patients operated on using two different techniques. Between 2001 and 2012, 353 patients (211 female and 142 male), aged 17-76 years (mean 44), underwent laparoscopic antireflux surgery. The study included patients who underwent a Toupet fundoplication or Wroblewski Tadeusz procedure (WTP). The mean age of the group was 47.77 years (17-80 years). Forty-nine (32.45%) patients had severe symptoms, 93 (61.58%) had mild symptoms and 9 (5.96%) had a single mild but intolerable sign of GERD. Eighty-six (56.95%) patients had a Toupet fundoplication and 65 (43.04%) had a WTP. The follow-up period was 18-144 months. The average operating time for Toupet fundoplication and the WTP procedure was 164 min (90-300 min) and 147 min (90-210 min), respectively. The perioperative mortality rate was 0.66%. The average post-operative hospitalization period was 5.4 days (2-16 post-operative days (POD) = Toupet) vs. 4.7 days (2-9 POD = WTP). No reoperations were performed. No major surgical complications were identified. Wroblewski Tadeusz procedure due to a low percentage of post-operative complications, good quality of life of patients and a zero recurrence rate of hiatal hernia should be a method of choice.

  1. [Expression of goat IL-18 mature protein in insect/baculovirus and determination of bioactivity of the recombinant protein].

    PubMed

    Wang, Ting-Ting; Wang, Xi-Hui; Fan, Zhong-Ling; Chen, Jin-Long; Cao, Bing-Lei; Kong, Na; Hu, Jing-Dong; Zhao, Hong-Kun

    2011-02-01

    To express goat IL-18 in insect/baculovirus and detect the bioactivity of the recombinant protein. The mature goat interleukin-18(gIL-18) gene was cloned into the baculovirus transfer vector pFastBac Dual, and then the resulting eukaryotic expression plasmid pFastBac Dual-gIL18 was transformed into DH10Bac, followed by the identification of Bacmid-gIL18 recombinat plosmid by three antibiotics and blue-white patch. Finally, the recombinant bacmid was transfected into sf9 insect cells by Cellfectin and the transfected cells were harvested at different times. Then the expressed protein was identified by SDS-PAGE, Western blot and bioactivity assay. The recombinant protein recognized and bound to its specific antibody. Bioactivity assay showed that the recombinant protein stimulated the proliferation of lymphocytes and induced IFN-γproduction in spleen lymphocytes. The mature gIL-18 protein has been expressed successfully in insect/baculovirus expression system, and have good immunogenicity and bioactivity. The study paves a way for application of gIL-18 as an immunomodulator or immune adjuvant.

  2. Surgical treatment of GERD. Comperative study of WTP vs. Toupet fundoplication – results of 151 consecutive cases

    PubMed Central

    Wróblewski, Tadeusz; Nowosad, Małgorzata; Krawczyk, Marek

    2016-01-01

    Introduction Gastroesophageal reflux disease (GERD) is recognized as one of the most common disorders of the upper gastrointestinal tract (GIT). The best choice of management for advanced GERD is laparoscopic surgery. Aim To compare and evaluate the results of surgical treatment of GERD patients operated on using two different techniques. Material and methods Between 2001 and 2012, 353 patients (211 female and 142 male), aged 17–76 years (mean 44), underwent laparoscopic antireflux surgery. The study included patients who underwent a Toupet fundoplication or Wroblewski Tadeusz procedure (WTP). Results The mean age of the group was 47.77 years (17–80 years). Forty-nine (32.45%) patients had severe symptoms, 93 (61.58%) had mild symptoms and 9 (5.96%) had a single mild but intolerable sign of GERD. Eighty-six (56.95%) patients had a Toupet fundoplication and 65 (43.04%) had a WTP. The follow-up period was 18–144 months. The average operating time for Toupet fundoplication and the WTP procedure was 164 min (90–300 min) and 147 min (90–210 min), respectively. The perioperative mortality rate was 0.66%. The average post-operative hospitalization period was 5.4 days (2–16 post-operative days (POD) = Toupet) vs. 4.7 days (2–9 POD = WTP). No reoperations were performed. No major surgical complications were identified. Conclusions Wroblewski Tadeusz procedure due to a low percentage of post-operative complications, good quality of life of patients and a zero recurrence rate of hiatal hernia should be a method of choice. PMID:27458484

  3. Prognostic Factors and Significance of Gastrointestinal Leak After Cytoreductive Surgery (CRS) with Heated Intraperitoneal Chemotherapy (HIPEC).

    PubMed

    Chouliaras, Konstantinos; Levine, Edward A; Fino, Nora; Shen, Perry; Votanopoulos, Konstantinos I

    2017-04-01

    Gastrointestinal leak (GIL) after cytoreductive surgery with heated intraperitoneal chemotherapy (CRS/HIPEC) is associated with significant morbidity and mortality. This study aimed to identify GIL prognostic factors and its impact on overall survival. A retrospective analysis of a prospectively maintained database comprising 1270 CRS/HIPEC procedures was performed. Type of GIL, functional and resection status, morbidity, mortality, and survival were reviewed. Gastrointestinal leaks were identified in 8.7% (110/1270) of CRS/HIPEC procedures, including 53 anastomotic leaks (4.2%), 53 hollow viscus perforations (4.2%), and four leaks at unknown sites. The multivariate predictors of leak were Eastern Cooperative Oncology Group (ECOG) functional status (ECOG 1 vs. 0: odds ratio [OR] 2.12, p = 0.009; ECOG 2 vs. 0: OR 2.90, p = 0.004), and number of anastomoses (OR 5.34; p < 0.0001). The in-hospital mortality rate for the GIL cohort was 21.8% (24/110), with a 72% (80/110) reoperation rate. The leak cohort had a higher major morbidity rate (88.3 vs. 23.3%; p < 0.0001), a longer hospital stay (39.0 vs. 9.9 days; p < 0.0001), and a longer intensive care unit (ICU) stay (7.7 vs. 1.7 days; p = 0.0003). After surgical mortality was excluded, the overall survival periods for the leak and no-leak patients with complete cytoreduction were respectively 1.5 and 4.98 years (p = 0.0001). Clinically significant decreases in survival were observed for all primary malignancies. Gastrointestinal leak after CRS/HIPEC is a source of significant mortality, with a decrease in overall survival even after complete CRS. Preoperative functional status and number of anastomoses are predictors of leak for CRS/HIPEC patients.

  4. 78 FR 44943 - State Energy Advisory Board (STEAB)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-25

    ...: Gil Sperling, STEAB Designated Federal Officer, U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, 1000 Independence Ave. SW., Washington, DC, 20585. Phone number is (202) 287...

  5. 78 FR 52171 - State Energy Advisory Board (STEAB)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-22

    ...: Gil Sperling, STEAB Designated Federal Officer, U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, 1000 Independence Ave. SW., Washington, DC 20585. Phone number is (202) 287-1644...

  6. 77 FR 20014 - State Energy Advisory Board (STEAB)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-03

    ...: Gil Sperling, STEAB Designated Federal Officer, U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, 1000 Independence Ave. SW., Washington, DC 20585. Phone number is (202) 287-1644...

  7. Seasonal dynamics of ixodid ticks on wild rabbits Oryctolagus cuniculus (Leporidae) from Central Spain.

    PubMed

    González, J; Valcárcel, F; Pérez-Sánchez, J L; Tercero-Jaime, J M; Olmeda, A S

    2016-11-01

    Rabbit Hemorrhagic Disease and Myxomatosis caused a decline in the rabbit population in the second half of the last century. Despite some recovery, the risk of vector-borne disease is present and thus the importance of controlling vector populations. In the current study, we describe the ixodid tick fauna in wild rabbit in a natural reserve in Ciudad Real (Central Spain) during the course of two 3-year periods (2007-2009 and 2012-2014). Of all the ticks collected on average 72.5 % were larvae, 24.4 % nymphs and 3.1 % adults, although the percentage varied monthly. Seven tick species were identified: Hyalomma lusitanicum Koch (Parasitic indicator [PI] = number of ticks per examined rabbit = 96.47), Rhipicephalus pusillus Gil Collado (PI = 47.37), Haemaphysalis hispanica Gil Collado (PI = 12.15), Ixodes ventalloi Gil Collado (PI = 0.65), R. bursa Canestrini and Fanzago (PI = 0.18), R. sanguineus Latreille (PI = 0.11), Dermacentor marginatus Sulzer (PI = 0.01). In spring and summer, most abundant were larvae of H. lusitanicum, followed by immature stages of R. pusillus and Ha. hispanica. In autumn, the main tick species were nymphs of I. ventalloi whereas in winter adults of Ha. hispanica were more numerous. Rhipicephalus pusillus was present all year long, although not always in high percentage. PI of other species (R. bursa, R. sanguineus and D. marginatus) were too low to be representative. The seasonal dynamics of ticks on wild rabbit defined in this study could be useful to design species-specific control strategies.

  8. A Memorial: Gilman Veith

    EPA Science Inventory

    Our colleague and good friend Gilman Veith died August 18th after a long battle with pancreatic cancer. Over his more than 40 year career Gil provided outstanding vision and inspirational leadership at both national and international levels. His efforts have been truly transform...

  9. Final Report of the KAPSE (Kernal Ada Programming Support Environment) Interface Team (KIT)

    DTIC Science & Technology

    1988-10-15

    Corporation Hans Mumm Naval Ocean Systems Center Bob Munck MITRE Margaret Murray Compusec Gil Myers Naval Ocean Systems Center LCDR Philip Myers NAVELEX-812...Data Corporation Steve Huseth Honeywell Ron Johnson Boeing Aerospace Corporation Mike Kamrad Honeywell , Reed Kotler Lockheed Missile and Space Pekka

  10. Implementation of a Project-Based Telecommunications Engineering Design Course

    ERIC Educational Resources Information Center

    Aliakbarian, Hadi; Soh, Ping Jack; Farsi, Saeed; Xu, Hantao; Van Lil, Emmanuel H. E. M. J. C.; Nauwelaers, Bart K. J. C.; Vandenbosch, Guy A. E.; Schreurs, Dominique M. M.-P.

    2014-01-01

    This paper describes and discusses the implementation of a project-based graduate design course in telecommunications engineering. This course, which requires a combination of technical and soft skills for its completion, enables guided independent learning (GIL) and application of technical knowledge acquired from classroom learning. Its main…

  11. Revista de Investigacion Educativa, 2002 (Journal of Educational Research, 2002).

    ERIC Educational Resources Information Center

    Revista de Investigacion Educativa, 2002

    2002-01-01

    This journal, which deals with topics in educational research, includes articles written in Spanish (translated here) such as the following: "Management of the Competence of Professional Action (CAP)]" (Benito Echeverria Samanes); "Concepts and Beliefs of Andalusian Secondary School Teachers on Mathematics Assessments" (Francisco Gil Cuadra, Luis…

  12. A New Java Animation in Peer-Reviewed "JCE" Webware

    ERIC Educational Resources Information Center

    Coleman, William F.; Fedosky, Edward W.

    2006-01-01

    "Computer Simulations of Salt Solubility" by Victor M. S. Gil provides an animated, visual interpretation of the different solubilities of related salts based on simple entropy changes associated with dissolution such as configurational disorder and thermal disorder. This animation can help improve students' conceptual understanding of…

  13. Kernel Ada Programming Support Environment (KAPSE) Interface Team. Public Report. Volume 3.

    DTIC Science & Technology

    1983-10-25

    NWC MYERS, Gil NOSC MYERS, Philip NAVELEX NELSON, Eldred TRW OBERNDORF, Tricia NOSC P E, Shirley FCDSSA 2A-10 PURRIER, Lee FCDSSA OTB ROBERTSON...Sciences Corp. GRIESHEIMER, Eric McDonnel Douglas Astronautics JOHNSON, Ron Boeing Aerospace Co. KERNER, Judy Norden Systems KOTLER , Reed Lockheed Missiles

  14. Occurrence, source and ecological assessment of baseline hydrocarbons in the intertidal marine sediments along the shoreline of Douglas Channel to Hecate Strait in British Columbia.

    PubMed

    Yang, Zeyu; Hollebone, Bruce P; Laforest, Sonia; Lambert, Patrick; Brown, Carl E; Yang, Chun; Shah, Keval; Landriault, Mike; Goldthorp, Michael

    2017-09-15

    The occurrence, source and ecological assessment of baseline hydrocarbons in the intertidal zone along the northern British shoreline were evaluated based on analyzing total petroleum hydrocarbons (TPH), n-alkanes, petroleum related biomarkers such as terpanes and steranes, and polycyclic aromatic hydrocarbons (PAHs) including non-alkylated and alkylated homologues (APAHs). The TPH levels, n-alkanes, petroleum biomarkers and PAHs in all the sampling sites, except for Masset Harbor/York Point at Gil Island were low, without obvious unresolved complex mixture (UCM) and petroleum contamination input. Specifically, n-alkanes showed a major terrestrial plants input; PAHs with abundant non-alkylated PAHs but minor APAHs showed a major pyrogenic input. However, obvious petroleum-derived hydrocarbons have impacted Masset Harbor. A historical petroleum input was found in York Point at Gil Island, due to the presence of the low level of petroleum biomarkers. Ecological assessment of 13 non-alkylated PAHs in Masset Harbor indicated no potential toxicity to the benthic organisms. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Berkeley Lab - Materials Sciences Division

    Science.gov Websites

    MSD Support Human Resources Facilities & Space Planning Procurement and Property Proposals & , Travel, Property Rosemary Williams, Purchasing & Time Keeper 510-495-2645 66-238 rmwilliams@lbl.gov Jasmine Harris, Travel & Property 510-486-6303 66-237 jaharris@lbl.gov Gil Torres, Building Manager

  16. Vocational Rehabilitation Counselors' Perceived Influences on the Secondary Transition Planning Process and Postsecondary Outcomes of Students with Disabilities

    ERIC Educational Resources Information Center

    Miller-Warren, Vickie

    2014-01-01

    Outside agencies such as vocational rehabilitation agencies are designed to help provide services such as job coaching, mental health services, tuition assistance, and life-skills training for students with disabilities during and after high school so that they may obtain postsecondary success (Gil, 2007). This study examined the perceived…

  17. Constraints on the Acquisition of Social Category Concepts

    ERIC Educational Resources Information Center

    Baron, Andrew Scott; Dunham, Yarrow; Banaji, Mahzarin; Carey, Susan

    2014-01-01

    Determining which dimensions of social classification are culturally significant is a developmental challenge. Some suggest this is accomplished by differentially privileging intrinsic visual cues over nonintrinsic cues (Atran, 1990; Gil-White, 2001), whereas others point to the role of noun labels as more general promoters of kind-based reasoning…

  18. Parental Insights on the Effects of the Secondary Transition Planning Process on the Postsecondary Outcomes of Graduates with Disabilities

    ERIC Educational Resources Information Center

    Miller-Warren, Vickie

    2016-01-01

    Research shows that transition planning for students with disabilities is an ongoing process that requires the collaboration of students, families, and teachers to ensure a successful adult life for students after graduation (Clark, 1996; Clark & Unruh, 2010; Gil, 2007; Kellems & Morningstar, 2010). This study examined the insights of the…

  19. Perilous Human Security in South Asia: Are There Ways Out?

    DTIC Science & Technology

    2011-03-21

    threats directed against women and child . Most people derive security from their membership in a group – a family, a community, an organization, a...Strategic Environment, 10-11. 84 Aun Porn Moniroth, “Economic Integration in East Asia – Cambodia’s Experience” in East Asian Visions, ed. Indermit Gil

  20. Measurement and Regulation of Central Noradrenergic Receptors

    DTIC Science & Technology

    1993-11-30

    reduction in swimming ( Armario et al., 1991). Propranolol and betaxolol when given alone both produced a similar reduction in acitivity and when given with...19:74, 1993. Literature cited in report Armario , A., Gil, %., Marti, J., Pol, 0. and Balasch, J. Pharmacol.Biochem.Behav. 39:373-377, 1991. Blanchard

  1. Pedagogical Strategies for Human and Computer Tutoring.

    ERIC Educational Resources Information Center

    Reiser, Brian J.

    The pedagogical strategies of human tutors in problem solving domains are described and the possibility of incorporating these techniques into computerized tutors is examined. GIL (Graphical Instruction in LISP), an intelligent tutoring system for LISP programming, is compared to human tutors teaching the same material in order to identify how the…

  2. Dialogue as a Tool for Meaning Making

    ERIC Educational Resources Information Center

    Bruni, Angela Suzanne Dudley

    2013-01-01

    In order to empower citizens to analyze the effects, risk, and value of science, a knowledge of scientific concepts is necessary (Mejlgaard, 2009). The formal educational system plays a role in this endeavor (Gil-Perez & Vilches, 2005). One proposed constructivist practice is the use of social learning activities using verbalized, shared…

  3. Teaching the Sociology of Sport: Using a Comic Strip in the Classroom.

    ERIC Educational Resources Information Center

    Snyder, Eldon E.

    1997-01-01

    Observes that contemporary sociology pays little attention to the narrative and graphic aspects of comic strips. Presents classroom experiences using "Gil Thorpe," a comic strip with an ongoing storyline about suburban high school athletics, and gives reasons for the effectiveness of this instructional tool in the sociology of sport.…

  4. Creating a Culture of Student Success: The SEEK Scholars Peer Mentoring Program

    ERIC Educational Resources Information Center

    Zevallos, Ana L.; Washburn, Mara

    2014-01-01

    Over the past decades, Vincent Tinto, Edmund Thile, Francis Ianni, and others all link mentoring to better academic performance, improved social adjustment, enhanced academic experiences, and greater rates of degree completion. Even more specifically, Jean E. Rhodes, Renée Spencer, Thomas E. Keller, Belle Liang, and Gil Noam describe three…

  5. KSC-2014-3629

    NASA Image and Video Library

    2014-08-06

    CAPE CANAVERAL, Fla. – NASA's Kurt Leucht, from left, is working with undergraduate intern Gil Montague and post-graduate intern Karl Stolleis to develop the software that will control independent robots in a way that mimics the process ants use to scout for and then collect resources. Photo credit: NASA/Dmitri Gerondidakis

  6. A systems-genetics approach and data mining tool to assist in the discovery of genes underlying complex traits in Oryza sativa.

    PubMed

    Ficklin, Stephen P; Feltus, Frank Alex

    2013-01-01

    Many traits of biological and agronomic significance in plants are controlled in a complex manner where multiple genes and environmental signals affect the expression of the phenotype. In Oryza sativa (rice), thousands of quantitative genetic signals have been mapped to the rice genome. In parallel, thousands of gene expression profiles have been generated across many experimental conditions. Through the discovery of networks with real gene co-expression relationships, it is possible to identify co-localized genetic and gene expression signals that implicate complex genotype-phenotype relationships. In this work, we used a knowledge-independent, systems genetics approach, to discover a high-quality set of co-expression networks, termed Gene Interaction Layers (GILs). Twenty-two GILs were constructed from 1,306 Affymetrix microarray rice expression profiles that were pre-clustered to allow for improved capture of gene co-expression relationships. Functional genomic and genetic data, including over 8,000 QTLs and 766 phenotype-tagged SNPs (p-value < = 0.001) from genome-wide association studies, both covering over 230 different rice traits were integrated with the GILs. An online systems genetics data-mining resource, the GeneNet Engine, was constructed to enable dynamic discovery of gene sets (i.e. network modules) that overlap with genetic traits. GeneNet Engine does not provide the exact set of genes underlying a given complex trait, but through the evidence of gene-marker correspondence, co-expression, and functional enrichment, site visitors can identify genes with potential shared causality for a trait which could then be used for experimental validation. A set of 2 million SNPs was incorporated into the database and serve as a potential set of testable biomarkers for genes in modules that overlap with genetic traits. Herein, we describe two modules found using GeneNet Engine, one with significant overlap with the trait amylose content and another with

  7. 15th Anniversary of the Molecular Techniques Unit at the Department of Forensic Medicine at Wroclaw Medical University.

    PubMed

    Pluta, Dominika; Tokarski, Miron; Karpiewska, Anna; Dobosz, Tadeusz

    2017-01-01

    Molecular Techniques Unit at the Department of Forensic Medicine, Wroclaw Medical University has been operating since December 2003. Soon it will be 15 years since its establishment. This anniversary become an inspiration to write down the story of this institution whose origins illustrate the immense changes that have taken place in forensic genetics. The aim of our work was also to consolidate the professional achievements of Professor Tadeusz Dobosz, chief of the Unit, one of the pioneers of introducing DNA testing technology into Polish forensic medicine. The most important achievements of the Unit include participation in two EU research projects, the development of a non-destructive method of extraction of genetic material, research in field of gene therapy and certification of the Laboratory of the Molecular Techniques Unit by the Polish Accreditation Center (PCA) confirming compliance with the requirements of the PN-EN ISO/IEC 17025:2005 standard.

  8. Automatic Representation Changes in Problem Solving

    DTIC Science & Technology

    1999-06-01

    Michael Cox, Rujith DeSilva, Rob Driskill, Karen Haigh, Vera Kettnaker, Craig Knoblock, Erica Melis, Steven Minton, Alicia Perez, Paola Rizzo, Yury...for a student of mathematics. Gestalt psychologists also paid particular attention to reformulation of problems [Duncker, 1945; Ohlsson , 1984...Carbonell et al., 1992] Jaime G. Carbonell, Jim Blythe, Oren Etzioni, Yolanda Gil, Robert Joseph, Dan Kahn, Craig A. Knoblock, Steven Minton, Alicia Perez

  9. Explosion Hazards Associated with Spills of Large Quantities of Hazardous Materials. Phase I

    DTIC Science & Technology

    1974-10-01

    quantities of hazardous material such as liquified natural gas ( LNG ), liquified petroleum gils (LPG), or ethylene. The principal results are (1) a...associated with spills of large quantities of hazardous material such as liquified natural gas ( LNG ), liquified petroleum gas (LPG), or ethylene. The...liquified natural gas ( LNG ). Unfortunately, as the quantity of material shipped at one time increases, so does the potential hazard associated with

  10. Meloquine Use and Hospitalizations Among US Service Members, 2002-2004

    DTIC Science & Technology

    2005-04-12

    name Lariam, was approved by the Food and Drug Administration on May 2, 1989, for malaria chemoprophylaxis.6 In 1990, the Centers for Disease...2005;293(2):212-216. 6. Food and Drug Administration. Approval history, Lariam. Available at: http://www.accessdata.fda.gov/scripts/cder...163-165. 26. Jimeniz-Huete A, Gil-Nagel A, Franch O. Multifocal myoclonus associated with mefloquine prophylaxis [letter]. Clin Neuropharmacol

  11. Athermal Mechanisms of Size-Dependent Crystal Flow Gleaned from Three-Dimensional Discrete Dislocation Simulations

    DTIC Science & Technology

    2008-01-01

    Sevillano, et. al . directly developed a definition of the single-slip glide-resistance correlation length, 10//5.8 o  , from 2d simulations of single...dislocation percolation through point-obstacle fields [35, 36]. Subsequently, predictions for the size- dependence of * from Gil Sevillano, et. al ...Sevillano, et. al ., and microcrystal deformation experiments was perhaps fortuitous, significant merit remains within their treatment. The more general

  12. Fort Knox Trend Analysis, Encroachment Study, and Perimeter Expansion Opportunities in Support of Military Training

    DTIC Science & Technology

    2006-03-01

    converters from GIL and many other formats. Other hilites: command line argument parsing, a simple set of routines for de- veloping Xwindows graphical...Ramakrishna Nemani, James E. Vogelmann, V. Ruth Hobson, Benjamin Tuttle, Jeff Safran, Ingrid Nelson. (2001). “Development Sprawl Impacts on the... Sale Prices as a Basis for Farm Land Appraisal,” Technical Bulletin, University of Minnesota. Hosmer, D.W., and S. Lemeshow. (1989). Applied

  13. Characterization and Expression of Drug Resistance Genes in MDROs Originating from Combat Wound Infections

    DTIC Science & Technology

    2014-10-01

    media so only adherent/close proximity bacterial cells were harvested . Cells were then treated with RNAprotect Cell Reagent (Qiagen) to immediately...2004, 32:2386-2395. 4. Chen Y, Stine OC, Badger JH, Gil AI, Nair GB, Nishibuchi M, Fouts DE: Comparative Genomic Analysis of Vibrio ...antigen biosynthesis regions in Vibrio cholerae. Applied and environmental microbiology 2011, 77:2247-2253. 6. Jacobsen A, Hendriksen RS, Aaresturp FM

  14. A Systems-Genetics Approach and Data Mining Tool to Assist in the Discovery of Genes Underlying Complex Traits in Oryza sativa

    PubMed Central

    Ficklin, Stephen P.; Feltus, Frank Alex

    2013-01-01

    Many traits of biological and agronomic significance in plants are controlled in a complex manner where multiple genes and environmental signals affect the expression of the phenotype. In Oryza sativa (rice), thousands of quantitative genetic signals have been mapped to the rice genome. In parallel, thousands of gene expression profiles have been generated across many experimental conditions. Through the discovery of networks with real gene co-expression relationships, it is possible to identify co-localized genetic and gene expression signals that implicate complex genotype-phenotype relationships. In this work, we used a knowledge-independent, systems genetics approach, to discover a high-quality set of co-expression networks, termed Gene Interaction Layers (GILs). Twenty-two GILs were constructed from 1,306 Affymetrix microarray rice expression profiles that were pre-clustered to allow for improved capture of gene co-expression relationships. Functional genomic and genetic data, including over 8,000 QTLs and 766 phenotype-tagged SNPs (p-value < = 0.001) from genome-wide association studies, both covering over 230 different rice traits were integrated with the GILs. An online systems genetics data-mining resource, the GeneNet Engine, was constructed to enable dynamic discovery of gene sets (i.e. network modules) that overlap with genetic traits. GeneNet Engine does not provide the exact set of genes underlying a given complex trait, but through the evidence of gene-marker correspondence, co-expression, and functional enrichment, site visitors can identify genes with potential shared causality for a trait which could then be used for experimental validation. A set of 2 million SNPs was incorporated into the database and serve as a potential set of testable biomarkers for genes in modules that overlap with genetic traits. Herein, we describe two modules found using GeneNet Engine, one with significant overlap with the trait amylose content and another with

  15. Kernel ADA Programming Support Environment (KAPSE) Interface Team Public Report. Volume 4.

    DTIC Science & Technology

    1984-04-30

    the document until further discussion has taken place among the group metbers. RACWG announced their editor, Reed Kotler . The RACWG plans to narrow...KRUTAR, Rudy NRL *LAPLANT, Bill HQ USAF LOPER, Warren NOSC *MAGLIERI, Lucas Canadian National Defense HQ MILLER, Jo NWC MYERS, Gil NOSC *MYERS, Philip ...HUMPHREY, Dianna Control Data Corp. JOHNSON, Ron Boeing Aerospace Co. KERNER, Judy Norden Systems KOTLER , Reed Lockheed Missiles & Space LAMB, J. Eli

  16. Modeling and Characterization of Phonon Transmission and Generation across Engineered and Strained Interfaces for Developing Structure-Property Relations of Functional Nanostructures

    DTIC Science & Technology

    2015-05-21

    translation of; report supersedes; old edition number, etc. 14. ABSTRACT. A brief (approximately 200 words) factual summary of the most significant... Chemistry C, Vol. 117, pp. 24716-24725, 2013. 21. Jose Ordonez-Miranda, Ronggui Yang, and J.J. Alvarado-Gil, A New Constitutive Equation for Nano-to...for attending ASME/IMECE 2012 in Houston, TX. Jun Liu, March 2012, “Most Excited Molecules” for his presentation at 12th GEAR2S Conference

  17. Thermal Decomposition Mechanisms of Alkylimidazolium Ionic Liquids with CN-containing Anions

    DTIC Science & Technology

    2014-11-01

    anion calculated at the M06/6-31+G(d,p) level of theory and using the generic ionic liquid (GIL) model to simulate the condensed phase methyl...decomposition mechanisms of alkylimidazolium ionic liquids with CN-containing anions 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d...perform, display, or disclose the work. 14. ABSTRACT Due to the unusually high heats of vaporization of room-temperature ionic liquids (RTILs

  18. Historical flood data series of Eastern Spanish Coast (14th-20th centuries). Improving identification of climatic patterns and human factors of flood events from primary documentary sources

    NASA Astrophysics Data System (ADS)

    Alberola, Armando; Barriendos, Mariano; Gil-Guirado, Salvador; Pérez-Morales, Alfredo; Balasch, Carles; Castelltort, Xavier; Mazón, Jordi; Pino, David; Lluís Ruiz-Bellet, Josep; Tuset, Jordi

    2016-04-01

    Historical flood data series of Eastern Spanish Coast (14th-20th centuries). Improving identification of climatic patterns and human factors of flood events from primary documentary sources Armando Alberola, Barriendos, M., Gil-Guirado, S., Pérez Morales, A., Balasch, C., Castelltort, X., Mazón, J., Pino, D., Ruiz-Bellet, J.L., Tuset, J. Historical flood events in eastern spanish coast have been studied by different research groups and projects. Complexity of flood processes, involving atmospheric, surface and human factors, is not easily understandable when long time series are required. Present analysis from PREDIFLOOD Project Consortium defines a new step of flood event databases: Improved access to primary (documentary) and secondary (bibliographical) sources, data collection for all possible locations where floods are detected, and improved system of classification (Barriendos et al., 2014). A first analysis is applied to 8 selected flood series. Long chronologies from PREDIFLOOD Project for Catalonia region (Girona, Barcelona, Tarragona, Lleida, Tortosa). In addition, to cover all sector of spanish mediterranean coast, we introduce Valencia city in Turia River basin. South Eastern sector is cover with Murcia and Caravaca cities, Segura River basin. Extension of area under study required contributions of research teams experienced in work of documentary primary sources (Alberola, 2006; Gil-Guirado, 2013). Flood frequency analysis for long scale periods show natural climatic oscillations into so-called Little Ice Age. There are general patterns, affecting most of basins, but also some local anomalies or singularities. To explain these differences and analogies it is not enough to use purely climatic factors. In this way, we analyze human factors that have been able to influence the variability of floods along last 6 centuries (demography, hydraulic infrastructures, urban development...). This approach improves strongly understanding of mechanisms producing

  19. Pascagoula Harbor, Mississippi. Feasibility Report on Improvement of the Federal Deep-Draft Navigation Channel. Volume 2. Technical Appendices. Revision.

    DTIC Science & Technology

    1985-03-01

    about half the time as the pipeline work, it would be logical for that work to begin about the middle of the period so all construction would finish ...d co)uld 𔃾’ -I to -rilch a plan i t c t C , . vy -;i- .: i m ’i, end o Iit coton . -p m -w 1u d ’if n;i ii 1 1in, ne, f e eco an .. i gil im 7" i

  20. Line-of-Sight Handbook

    DTIC Science & Technology

    1977-01-01

    6000 8000 1000012000i400016000 =00 RANGE.,M90 6 X0O0 4000 0󈧄 1OO toooo4oo RRNGE,M FIGURE 96. Site CHS 1: Probabilty of LOS as a Function of (A...4500 iGil NALTITUDE, M ~-0 (b) R n () &*1500 4000 MNG~,30000 20bo 406d &600 Soho IQ;;o 12W7oWo ii1o RANGE, M FICURE 136. Site CHE 2: Probabilty of LOS

  1. Housing Operations Management System (HOMES). Volume 1. Executive Summary

    DTIC Science & Technology

    1984-08-01

    output products become available. One of these products is the Reimburs - able Order and Contract Ledger. By entering a Reimbursable Order (RO) Number or...Development Products Menu 108 G8 HOMES Budget Execution Menu 109 G9 Budget Execution Flow 110 G1O Commitments and Obligations Ledger il1 Gil Reimbursable ...are in a specified percentage range liquidated. Figure ClI shows the format of the Reimbursable Order and Contract Ledger. Figure 012 shows the

  2. Direct bioactive ceramics coating via reactive Growing Integration Layer method on α-Ti-alloy.

    PubMed

    Huang, Chi-Huang; Chen, Rong-Sheng; Yoshimura, Masahiro

    2017-07-01

    This paper demonstrates Ca-P-rich bio-ceramic and hydroxyapatite (HA) coatings formed directly from the solution of calcium acetate (CA) and sodium dihydrogen phosphate (SDP) on α-Ti-alloy substrates by Growing Integration Layer (GIL) technology under DC power supply. The composition of the α-Ti-alloy was Ti7Cu5Sn. The GIL coated films formed in 30min time with different voltages applied had porous and rough ceramic surfaces. They consisted mostly of various oxides like rutile, anatase, and calcium phosphates (including hydroxyapatite) that reduce corrosion rate and increase biocompatibility. An important feature was the reduction of Cu at the surfaces of the alloys. Furthermore, along with the applied voltage, the content of HA, the size of micro-pores, and hardness all increased, while the number of micro-pores in the ceramic membrane got reduced. The potential, current and resistance of corrosion were identified by potentiodynamic (PD) polarization and electrochemical impedance spectroscopy (EIS). The higher applied voltage improved the surface quality, HA formation rate, and the anti-corrosion behavior. Consequently, the samples - prepared at 350V and surface current density of 3A/cm 2 - possessed the most compact HA films, and also had the best corrosion resistance - in 0.9wt% NaCl solution at 37±1°C. Copyright © 2017. Published by Elsevier B.V.

  3. Time-Bound Analytic Tasks on Large Data Sets Through Dynamic Configuration of Workflows

    DTIC Science & Technology

    2013-11-01

    Assessment and Efficient Retrieval of Semantic Workflows.” Information Systems Journal, . 2012. [2] Blei, D., Ng, A., and M . Jordan. “Latent Dirichlet...25 (561-567), 2009. [5] Furlani, T. R., Jones, M . D., Gallo, S. M ., Bruno, A. E., Lu, C., Ghadersohi, A., Gentner, R. J., Patra, A., DeLeon, R. L...Proceedings of the IEEE e- Science Conference, Oxford, UK, pages 244–351. 2009. [8] Gil, Y.; Deelman, E.; Ellisman, M . H.; Fahringer, T.; Fox, G.; Gannon, D

  4. Role of NuSAP in Prostate Tumor Progression

    DTIC Science & Technology

    2012-06-01

    12: R64. 14 Amemiya H, Menolascino F, Pena A. Role of the expression of c-Met receptor in the progression of gastric cancer. Invest Clin 2010; 51: 369... histopathologic effects and biochemical recurrence. Urology 2004; 63: 1184 - 1190. 25 Monge M, Colas E, Doll A, Gil-Moreno A, Castellvi J, Diaz B et al...protein 6, a proliferation marker superior to Ki-67 and independent predictor of survival in patients with mantle cell lymphoma . Br J Cancer 2005; 93

  5. Gene Regulation by Retinoid Receptors in Human Mammary Epithelial Cells

    DTIC Science & Technology

    2002-10-01

    ceptors for collagen and fibronectin in human fibrosarcoma cells possessing Xia, Y-, S.G. Gil, and W.G. Carter. 1996. Anchorage mediated by integrin...simultaneously block all TdT terminal deoxynucleotidyl transferase pRB retinoblastoma protein wild-type RAR isoforms (-o, -P, and -- ) (Damm et CAT ...P0 pM treated with 0, 0,1, 1.0, or 10 jIM ATRA for 24 hours and cell lysates were assayed for CAT reporter activity. pCMV-GH was used as a transfection

  6. A Dynamic Computer Model to Examine Selected Effects of 304XX Career Field Consolidation.

    DTIC Science & Technology

    1982-09-01

    DEPARTMENT OF THE AIR FORCED AIR UNIVERSITY (ATC) -; AIR FORCE INSTITUTE OF TECHNOLOGY D" "-gil tio "-: -I- -.- hA-W ig tP ttro Air, .’ Force Bas...The contents of tihe document are technically accurate, and no sensitive item., detrimeatal Ideas, or deleteriqu information are contained...ADDRESS O. PNOGAM ELEMENT. PROJECT, TASKAPE • WOe,6U" NUMERmsacT Scho6l of Systems and Logistics .A W N. " Air Force Institute of Technology , WPAFB It

  7. Dynamical systems theory and applications

    NASA Astrophysics Data System (ADS)

    Awrejcewicz, Jan

    2006-08-01

    The 7th International Conference devoted to "Dynamical Systems-Theory and Applications" hold in 8-11 December, 2003 in Łódź, Poland, and it was organized by the staff of Department of Automatics and Biomechanics of the Technical University of Łódź. It was financially supported by the Rector of the Technical University of Łódź and the Department of Education and Physical Culture of the Łódź City Hall. The members of the International Scientific Committee included: Igor V. Andrianov (Dniepropetrovsk), Jan Awrejcewicz (Łódź), Iliya Blekhman (Sankt Petersburg), Roman Bogacz (Warszawa), Dick van Campen (Eindhoven), Zbigniew Engel (Kraków), Lothar Gaul (Stuttgart), Józef Giergiel (Kraków), Michał Kleiber (Warszawa), Vadim A. Krysko (Saratov), Włodzimierz Kurnik (Warszawa), Claude-Henri Lamarque (Lyon), Leonid I. Manevitch (Moscow), Jan Osiecki (Warszawa), Wiesaw Ostachowicz (Gdańsk), Ladislav Pust (Prague), Giuseppe Rega (Rome), Tsuneo Someya (Tokyo), Zbigniew Starczewski (Warszawa), Eugeniusz Świtoński (Gliwice), Andrzej Tylikowski (Warszawa), Tadeusz Uhl (Kraków), Aleksander F. Vakakis (Illinois), Józef Wojnarowski (Gliwice).

  8. Increasing severity of damage caused by floods in the Spanish Mediterranean coast (1960-2014), climate change or vulnerability?

    NASA Astrophysics Data System (ADS)

    Perez, Alfredo; Gil, Salvador; Lopez, Francisco; Barriendos, Mariano

    2016-04-01

    In recent decades, there has been an increase in physical and economic losses (WMO, CRED and UCL, 2014) that raises serious concerns in society. Climate change projections may explain the rise in flood losses; however, these shouldn't be considered yet (Bouwer, 2011). According to IPCC (2014), there is low confidence in anthropogenic climate change affecting the frequency and magnitude of fluvial floods on a global scale. In other words, this increase in flood events is not completely related to the higher frequency of heavy rainfall. To illustrate the aforementioned, a spatial example can be seen in the study area. In the Spanish Mediterranean coast, we see an increase in economic losses within the last 50 years due to flood events (Gil et al., 2014). It seems that the socio-economic growth and the rise of housing construction (Gaja, 2008) have led to an increase in vulnerability and exposure which are mainly responsible for those losses and the increase in severity of flood events (Pérez et al., 2015). Furthermore, this situation will probably become more precarious if some climate forecasts are met [IPCC, 2014; AEMET, 2015], and if the economic model fails to adopt efficient adaptive measures. Therefore, it is interesting to focus attention on social factors either within the present or future scenario in order to minimise the potential consequences and improve the adaptation. The main objective of this work focuses on the study of the evolution of the severity of the floods in the Spanish Mediterranean coast for the period (1960-2015). To do that, a statistical analysis of the data base [Gil et al., 2014; extended to the entire Spanish Mediterranean coast (MEDIFLOOD)] and a multiscale mapping (local, provincial and regional level) of the frequency of these events will take place in order to make comparisons and show spatiotemporal patterns according to the severity events evolution. Preliminary results show some interesting statistically significant

  9. Commission 20: Position and Motion of Minor Planets, Comets and Satellites

    NASA Astrophysics Data System (ADS)

    Valsecchi, Giovanni B.; Fernandez, Julio; Bowell, Edward L. G.; Arlot, Jean-Eudes; Bowell, Edward L. G.; Chernetenko, Yulia A.; Chesley, Steven R.; Lazzaro, Daniela; Lemaitre, Anne; Marsden, Brian G.; Muinonen, Karri; Rickman, Hans; Tholen, David J.; Yoshikawa, Makoto

    2007-12-01

    A total of 16 among the new IAU members have asked to join Commission 20; they are: Jerome Berthier, Nicholas J. Cooper, Marco Delbò, Romina P. Di Sisto, Michael W. Evans, Tetsuharu Fuse, Ludmila Hudkova, Yurij N. Krugly, Elena N. Polyakhova, Zhanna Pozhalova, Alessandro Rossi, Qi Rui, Jonathan D. Shanklin, Slawomira E. Szutowicz, Gino Tuccari and Hong-Suh Yim. Moreover, two requests to join the Commission have been received by astronomers that are already IAU members: Peter De Cat and Ricardo A. Gil-Hutton.

  10. Image steganography based on 2k correction and coherent bit length

    NASA Astrophysics Data System (ADS)

    Sun, Shuliang; Guo, Yongning

    2014-10-01

    In this paper, a novel algorithm is proposed. Firstly, the edge of cover image is detected with Canny operator and secret data is embedded in edge pixels. Sorting method is used to randomize the edge pixels in order to enhance security. Coherent bit length L is determined by relevant edge pixels. Finally, the method of 2k correction is applied to achieve better imperceptibility in stego image. The experiment shows that the proposed method is better than LSB-3 and Jae-Gil Yu's in PSNR and capacity.

  11. Is NIPARS Working as Advertised? An Analysis of NIPARS Program Customer Service

    DTIC Science & Technology

    1992-09-01

    AD-A259 733IN I II I ll IMiiiI Gil III 11 AFIT/GLM/LSM/92S- 17 IS NIPARS WORKING AS ADVERTISED ? AN ANALYSIS OFNIPARS PROGRAM CUSTOMER SERVICE THESIS...and/or Dist Speoiai. AFIT/GLM/LSM/92S-17 IS NIPARS WORKING AS ADVERTISED ? AN ANALYSIS OF NIPARS PROGRAM CUSTOMER SERVICE THESIS Presented to the...measures. x1i IS NIPARS WORKING AS ADVERTISED ? AN ANALYSIS OF NIPARS PROGRAM CUSTOMER SERVICE L Introduction 1.1 Overview Foreign policy must start with

  12. Transcriptional Regulation of Mouse Ribosomal RNA Synthesis by Pathways Involving Protein Kinase C, Calcium, Insulin and Serum

    DTIC Science & Technology

    1992-05-08

    Southern California 1ha.iITRINUTIONI AVAILASILITY STATEMENT 12b. DITIUINCCD1 This document has been approved { OSRUTO for public release and sale ...and 500 gIl of CHCI3 : Isoamyl alcohol (24 : 1), and 2X with 1ml of CHCI 3 : Iso amyl alcohol (24 : 1). RNA was precipitated at -200C overnight in the...control. Plasmid constructions. Plasmids pMrA and pMrD (Kuhn and Grummt, 1987) were kind gifts of Dr. Ingrid Grummt. Plasmid p119 and p123 (Arnhiem

  13. Bibliography on Cold Regions Science and Technology. Volume 52. Part 2,

    DTIC Science & Technology

    1998-12-01

    eng] 52-5087 spheric gases from antarctic ice cores. Gillaik, T., et al, in sediments and biota from four US arctic lakes. Allen-Gil, Study of the...1996,eng] 52-2678 52-690 Solomon , S., et at, [1997,eng] 52-879 Studies of cloud ice water path and optical thickness during Homogeneous ice...of clouds: a wave ota, D., et al, [1995,eng] 52-5364 flash rate. Solomon , R.C., [1997,eng] 52-1070 cloud case study . Ackerman, S.A., et al, [1998,eng

  14. Military Professionalism and Political Influence: A Case Study of the Mexican Military, 1917-1940

    DTIC Science & Technology

    1992-01-01

    producto nacional," in Mexico , 50 afios de revoluci6n: La economia , pp. 578, and 588-589. 2 2 Ibid., pp. 588-589. 2 3 james W. Wilkie, The Mexican...by M.R. Van Gils. Belgium: Rotterdam University Press, 1971, pp. 247-265. M~xico, 50 ahos de revoluci6n: La economia . Mexico , D.F.: Fondo de Cultura...government. Thus, Mexico is an ix extremely intpresting case to examine, not only because it is one of ½.ie few nations in Latin America that has enjoyed a

  15. Chromosome-Encoded Broad-Spectrum Ambler Class A β-Lactamase RUB-1 from Serratia rubidaea

    PubMed Central

    Didi, Jennifer; Ergani, Ayla; Lima, Sandra

    2016-01-01

    ABSTRACT Whole-genome sequencing of Serratia rubidaea CIP 103234T revealed a chromosomally located Ambler class A β-lactamase gene. The gene was cloned, and the β-lactamase, RUB-1, was characterized. RUB-1 displayed 74% and 73% amino acid sequence identity with the GIL-1 and TEM-1 penicillinases, respectively, and its substrate profile was similar to that of the latter β-lactamases. Analysis by 5′ rapid amplification of cDNA ends revealed promoter sequences highly divergent from the Escherichia coli σ70 consensus sequence. This work further illustrates the heterogeneity of β-lactamases among Serratia spp. PMID:27956418

  16. ARC-2010-ACD10-0011

    NASA Image and Video Library

    2010-01-26

    Small Business Council meeting hosed by NASA Ames Research Center: Naeemah Lee, H.Q., Cheryl Harrison, JSC, Gil DelVaile, GSRC, Mary Helen Ruiz, JPL, David Grove, HQ, John Cecconi, NSSC, Sandra Morris, HQ/OP, Michelle Stracener, SSC, Randy Manning, LaRC, Vernon Vann, LaRC, David Brock, MSFC, Ben Henson, MSFC, Larry Third, KSC, Robert Medina, DFRC, Christine Munroe, ARC, Lupe M. Velasquez, ARC, Monica F. Craft, JSC (?), Angel Castillo, NMO, Timothy C Pierce, GRC, Charles Williams, JSC, Jennifer Perez, GSFC, Rosa Acevedo, GSFC, Glenn A Delgado, HQ/Assoc Admin for Small Business, Tabisa Tepfer, HQ/OSBP/MORIAssoc, Richard Mann, HQ/OSBP

  17. Maximizing capture of gene co-expression relationships through pre-clustering of input expression samples: an Arabidopsis case study.

    PubMed

    Feltus, F Alex; Ficklin, Stephen P; Gibson, Scott M; Smith, Melissa C

    2013-06-05

    In genomics, highly relevant gene interaction (co-expression) networks have been constructed by finding significant pair-wise correlations between genes in expression datasets. These networks are then mined to elucidate biological function at the polygenic level. In some cases networks may be constructed from input samples that measure gene expression under a variety of different conditions, such as for different genotypes, environments, disease states and tissues. When large sets of samples are obtained from public repositories it is often unmanageable to associate samples into condition-specific groups, and combining samples from various conditions has a negative effect on network size. A fixed significance threshold is often applied also limiting the size of the final network. Therefore, we propose pre-clustering of input expression samples to approximate condition-specific grouping of samples and individual network construction of each group as a means for dynamic significance thresholding. The net effect is increase sensitivity thus maximizing the total co-expression relationships in the final co-expression network compendium. A total of 86 Arabidopsis thaliana co-expression networks were constructed after k-means partitioning of 7,105 publicly available ATH1 Affymetrix microarray samples. We term each pre-sorted network a Gene Interaction Layer (GIL). Random Matrix Theory (RMT), an un-supervised thresholding method, was used to threshold each of the 86 networks independently, effectively providing a dynamic (non-global) threshold for the network. The overall gene count across all GILs reached 19,588 genes (94.7% measured gene coverage) and 558,022 unique co-expression relationships. In comparison, network construction without pre-sorting of input samples yielded only 3,297 genes (15.9%) and 129,134 relationships. in the global network. Here we show that pre-clustering of microarray samples helps approximate condition-specific networks and allows for dynamic

  18. Maximizing capture of gene co-expression relationships through pre-clustering of input expression samples: an Arabidopsis case study

    PubMed Central

    2013-01-01

    Background In genomics, highly relevant gene interaction (co-expression) networks have been constructed by finding significant pair-wise correlations between genes in expression datasets. These networks are then mined to elucidate biological function at the polygenic level. In some cases networks may be constructed from input samples that measure gene expression under a variety of different conditions, such as for different genotypes, environments, disease states and tissues. When large sets of samples are obtained from public repositories it is often unmanageable to associate samples into condition-specific groups, and combining samples from various conditions has a negative effect on network size. A fixed significance threshold is often applied also limiting the size of the final network. Therefore, we propose pre-clustering of input expression samples to approximate condition-specific grouping of samples and individual network construction of each group as a means for dynamic significance thresholding. The net effect is increase sensitivity thus maximizing the total co-expression relationships in the final co-expression network compendium. Results A total of 86 Arabidopsis thaliana co-expression networks were constructed after k-means partitioning of 7,105 publicly available ATH1 Affymetrix microarray samples. We term each pre-sorted network a Gene Interaction Layer (GIL). Random Matrix Theory (RMT), an un-supervised thresholding method, was used to threshold each of the 86 networks independently, effectively providing a dynamic (non-global) threshold for the network. The overall gene count across all GILs reached 19,588 genes (94.7% measured gene coverage) and 558,022 unique co-expression relationships. In comparison, network construction without pre-sorting of input samples yielded only 3,297 genes (15.9%) and 129,134 relationships. in the global network. Conclusions Here we show that pre-clustering of microarray samples helps approximate condition

  19. Chromosome-Encoded Broad-Spectrum Ambler Class A β-Lactamase RUB-1 from Serratia rubidaea.

    PubMed

    Bonnin, Rémy A; Didi, Jennifer; Ergani, Ayla; Lima, Sandra; Naas, Thierry

    2017-02-01

    Whole-genome sequencing of Serratia rubidaea CIP 103234 T revealed a chromosomally located Ambler class A β-lactamase gene. The gene was cloned, and the β-lactamase, RUB-1, was characterized. RUB-1 displayed 74% and 73% amino acid sequence identity with the GIL-1 and TEM-1 penicillinases, respectively, and its substrate profile was similar to that of the latter β-lactamases. Analysis by 5' rapid amplification of cDNA ends revealed promoter sequences highly divergent from the Escherichia coli σ 70 consensus sequence. This work further illustrates the heterogeneity of β-lactamases among Serratia spp. Copyright © 2017 American Society for Microbiology.

  20. [The tragic doubt].

    PubMed

    Musial, G

    2001-01-01

    Starting with two statements made by two great artists and witnesses of the XXth century - Joseph Brodsky and the Polish poet, Tadeusz Rozewicz - the author discusses the roots of our current moral crisis to which we ourselves bear witness: in the unchecked population explosion (Brodsky), and in the sinister legacy of World War II, the effects of which we witness on a daily basis (Rozewicz). The author recalls a third witness: Czeslaw Milosz, who wrote that the world's progress exhibits an inevitable tendency toward nihilism. In his discourse with the three statements mentioned, the author refers to certain XXth century intellectuals - Ortega y Gasset, Cardinal Joseph Ratzinger, Mircea Eliade, Herbert Read - who confirm and develop the thesis of man s spiritual fall and rejection of transcendence through technology. The author further illustrates his thesis with examples taken from the scientific research concerning IT, cloning, euthanasia, as well as from the world of the arts from the apocalyptic works of Hieronymous Bosch and Pieter Bruegel the Elder to the latest performers. He invokes a worldview which, by rejecting the metaphysics of man s birth, aging, and death, also rejects the judeo-christian taboo of the human body as a "dwelling place for the spirit" (porno festivals, exhibitions of human corpses by Prof. von Hagens in Germany).

  1. Controlling cytoplasmic c-Fos controls tumor growth in the peripheral and central nervous system.

    PubMed

    Gil, Germán A; Silvestre, David C; Tomasini, Nicolás; Bussolino, Daniela F; Caputto, Beatriz L

    2012-06-01

    Some 20 years ago c-Fos was identified as a member of the AP-1 family of inducible transcription factors (Angel and Karin in Biochim Biophys Acta 1072:129-157, 1991). More recently, an additional activity was described for this protein: it associates to the endoplasmic reticulum and activates the biosynthesis of phospholipids (Bussolino et al. in FASEB J 15:556-558, 2001), (Gil et al. in Mol Biol Cell 15:1881-1894, 2004), the quantitatively most important components of cellular membranes. This latter activity of c-Fos determines the rate of membrane genesis and consequently of growth in differentiating PC12 cells (Gil et al. in Mol Biol Cell 15:1881-1894, 2004). In addition, it has been shown that c-Fos is over-expressed both in PNS and CNS tumors (Silvestre et al. in PLoS One 5(3):e9544, 2010). Herein, it is shown that c-Fos-activated phospholipid synthesis is required to support membrane genesis during the exacerbated growth characteristic of brain tumor cells. Specifically blocking c-Fos-activated phospholipid synthesis significantly reduces proliferation of tumor cells in culture. Blocking c-Fos expression also prevents tumor progression in mice intra-cranially xeno-grafted human brain tumor cells. In NPcis mice, an animal model of the human disease Neurofibromatosis Type I (Cichowski and Jacks in Cell 104:593-604, 2001), animals spontaneously develop tumors of the PNS and the CNS, provided they express c-Fos (Silvestre et al. in PLoS One 5(3):e9544, 2010). Treatment of PNS tumors with an antisense oligonucleotide that specifically blocks c-Fos expression also blocks tumor growth in vivo. These results disclose cytoplasmic c-Fos as a new target for effectively controlling brain tumor growth.

  2. Numerical analysis of air-flow and temperature field in a passenger car compartment

    NASA Astrophysics Data System (ADS)

    Kamar, Haslinda Mohamed; Kamsah, Nazri; Mohammad Nor, Ahmad Miski

    2012-06-01

    This paper presents a numerical study on the temperature field inside a passenger's compartment of a Proton Wira saloon car using computational fluid dynamics (CFD) method. The main goal is to investigate the effects of different glazing types applied onto the front and rear windscreens of the car on the distribution of air-temperature inside the passenger compartment in the steady-state conditions. The air-flow condition in the passenger's compartment is also investigated. Fluent CFD software was used to develop a three-dimensional symmetrical model of the passenger's compartment. Simplified representations of the driver and one rear passenger were incorporated into the CFD model of the passenger's compartment. Two types of glazing were considered namely clear insulated laminated tint (CIL) with a shading coefficient of 0.78 and green insulated laminate tint (GIL) with a shading coefficient of 0.5. Results of the CFD analysis were compared with those obtained when the windscreens are made up of clear glass having a shading coefficient of 0.86. Results of the CFD analysis show that for a given glazing material, the temperature of the air around the driver is slightly lower than the air around the rear passenger. Also, the use of GIL glazing material on both the front and rear windscreens significantly reduces the air temperature inside the passenger's compartment of the car. This contributes to a better thermal comfort condition to the occupants. Swirling air flow condition occurs in the passenger compartment. The air-flow intensity and velocity are higher along the side wall of the passenger's compartment compared to that along the middle section of the compartment. It was also found that the use of glazing materials on both the front and rear windscreen has no significant effects on the air-flow condition inside the passenger's compartment of the car.

  3. [Dr. Tadeusz Rakowiecki (July 26, 1878-April 6, 1965), physician, astronomer and writer--on the 25th anniversary of his death].

    PubMed

    Wiechowski, W

    He decided to study medicine to be self-reliant and helpful for the society though he showed outstanding abilities to exact sciences, in particular mathematics. He was graduated at the Warsaw University in 1903 "cum eximia laude" in medicine. Apart from medicine he had disclosed interest in literature that was realized by many lectures and publications related to the famous and outstanding Polish writer Stefan Zeromski. Since 1930 Dr. Rakowiecki has started as self-taught astronomy studies becoming soon one of seven most eminent Polish astronomers. In the thirties there appeared his two-volume monography entitled "Drogi Planet i Komet" ("Motions of planets and comets") that has become the first fundamental Polish handbook of astronomy actual up to seventies. His scientific achievements based on higher mathematics included 20 important reports on astronomy and several monographs on mathematics. In 1930 he had refused several proposals to head University Chairs of Astronomy, among others in Lwów, due to modesty and his willingness to help and to serve his patients. He had been a demon for work, his rest after admission of patients were astronomy calculations, while when tired with the latters he became occupied with medicine.

  4. [Level of education comparing to eating behaviours and anthropometrical indicators of nutritional status among men of Cracovian population].

    PubMed

    Gacek, Maria; Chrzanowska, Maria

    2009-01-01

    The purpose of this study was to estimate of educating level effect as one indicator of social status on eating behaviours and anthropometrical parameters of nutritional status in professionally active men aged 20-60 at city environment. The research was conducted into 1320 workers of Tadeusz Sendzimir's Steelworks in Cracov. The research tool was the author's questionnaire which included questions about meal consumption regularity and frequency of consuming selected groups of foodstuffs. The indicators of nutritional status were fixed on the base of anthropometrical measurements, whereas the body content was estimated by method of bioimpendation with the use of electronic scales TBF-300P. Differentiation of some eating behaviours depending on the level of education was proved; but one cannot definitely estimate the relation of these parameters, as the higher educated people aged 40-60 years old more frequently declare two meal style of eating and more often consume confectionery than the lower educated; in turn vocationally educated men aged 20-40 more often declare consuming fast food products. Statistically considerable differentiation in some anthropometrical indicators of nutritional status depending of the level of education among men aged 40-60 was also proved. Men of vocational education are characterized by the highest value of WHR indicator but at the same time lower value of the 4 skin-fatty folds sum than higher educated people.

  5. Genetic examination of the putative skull of Jan Kochanowski reveals its female sex

    PubMed Central

    Kupiec, Tomasz; Branicki, Wojciech

    2011-01-01

    We report the results of genetic examination of the putative skull of Jan Kochanowski (1530-1584), a great Polish renaissance poet. The skull was retrieved in 1791 by historian Tadeusz Czacki from the Kochanowski family tomb and became the property of the Czartoryskis Museum in Krakow. An anthropological study in 1926 questioned its male origin, which raised doubts about its authenticity. Our report presents genetic evidence that resolves this dispute. From the sole tooth we obtained a sufficient amount of DNA to perform the analysis of nuclear markers. The analysis of the sex-informative part of intron 1 in amelogenin, genotyped using AmpFiSTR® NGM PCR Amplification Kit and Powerplex® ESI17 Kit human identification systems, revealed the female origin of the tooth. The female origin was further confirmed by the analysis of a portion of amelogenin intron 2, a microsatellite marker located on the X chromosome, as well as by a lack of signal from Y chromosomal microsatellite markers and the sex-determining region Y marker. Data obtained for two hypervariable regions, HVI and HVII, in mitochondrial DNA showed that mtDNA haplotype was relatively frequent among contemporary Europeans. The analysis of a set of single nucleotide polymorphisms relevant for prediction of the iris color indicated an 87% probability that the woman had hazel or brown eye color. PMID:21674838

  6. Genetic examination of the putative skull of Jan Kochanowski reveals its female sex.

    PubMed

    Kupiec, Tomasz; Branicki, Wojciech

    2011-06-01

    We report the results of genetic examination of the putative skull of Jan Kochanowski (1530-1584), a great Polish renaissance poet. The skull was retrieved in 1791 by historian Tadeusz Czacki from the Kochanowski family tomb and became the property of the Czartoryskis Museum in Krakow. An anthropological study in 1926 questioned its male origin, which raised doubts about its authenticity. Our report presents genetic evidence that resolves this dispute. From the sole tooth we obtained a sufficient amount of DNA to perform the analysis of nuclear markers. The analysis of the sex-informative part of intron 1 in amelogenin, genotyped using AmpFiSTR® NGM PCR Amplification Kit and Powerplex® ESI17 Kit human identification systems, revealed the female origin of the tooth. The female origin was further confirmed by the analysis of a portion of amelogenin intron 2, a microsatellite marker located on the X chromosome, as well as by a lack of signal from Y chromosomal microsatellite markers and the sex-determining region Y marker. Data obtained for two hypervariable regions, HVI and HVII, in mitochondrial DNA showed that mtDNA haplotype was relatively frequent among contemporary Europeans. The analysis of a set of single nucleotide polymorphisms relevant for prediction of the iris color indicated an 87% probability that the woman had hazel or brown eye color.

  7. Mamun-TKC parathyroid retractor: Parathyroid glands squashed or scooped!

    PubMed

    Mahmud, Syed Mamun

    2015-03-01

    Parathyroid gland by its physiologic and anatomic diversity has interestingly been dealt by multiple specialties, including Urology. Besides primary hyperparathyroidism, urologists in close working relationship with nephrologists, tend to get referrals for tertiary hyperparathyroidism. Data from 1999 to 2012 was retrieved for all parathyroidectomies. Medical record of only cases undergoing parathyroidectomy utilising the instrument Mamun-TKC Parathyroid Retractor were reviewed. It is a metal body surgical instrument resembling Gil Vernet retractor having functional flat metal head attached to solid long handle, designed in two forms; one 'Straight' and other 'Angled' at 30°. During the period, 28 cases of parathyroidectomies were performed. The instrument was used in two cases. It was found to facilitate dissection, retraction and pedicle ligation of parathyroid gland by a-traumatic handling.

  8. The impact of nano-coating on surface charge accumulation of epoxy resin insulator: characteristic and mechanism

    NASA Astrophysics Data System (ADS)

    Qi, Bo; Gao, Chunjia; Lv, Yuzhen; Li, Chengrong; Tu, Youping; Xiong, Jun

    2018-06-01

    The flashover phenomenon of the insulator is the main cause for insulating failure of GIS/GIL, and one of the most critical impacting factors is the accumulation of surface charge. The common methods to restrain the surface charge accumulation are reviewed in this paper. Through the reasonable comparison and analysis of these methods, nano-coatings for the insulator were selected as a way to restrain the surface charge accumulation. Based on this, six nano-coated epoxy resin samples with different concentrations of P25-TiO2 nanoparticles were produced. A high precision 3D surface charge measurement system was developed in this paper with a spatial resolution of 4.0 mm2 and a charge resolution of 0.01 µC (m2 · mV)‑1. The experimental results for the epoxy resin sample showed that with the concentration of nanoparticles of the coating material increasing, the surface charge density tended to first decrease and then increase. In the sample coated with 0.5% concentration of nanoparticles, the suppression effect is the optimum, leading to a 63.8% reduction of charge density under DC voltage. The application test for actual nano-coated GIS/GIL basin insulator indicated that the maximum suppression degree for the charge density under DC voltage could reach 48.3%, while it could reach 22.2% for switching impulse voltage and 12.5% for AC context. The control mechanism of nano-coatings on charge accumulation was proposed based on the analysis for surface morphology features and traps characteristics; the shallow traps dominate in the migration of charges while the deep traps operate on the charge accumulation. With the concentration of nanoparticles in nano-coating material mounting up, the density of shallow traps continuously increases, while for deep traps, it first decreases and then increases. For the sample with 0.5% concentration of nanoparticles coated, the competition between shallow traps and deep traps comes to the most balanced state, producing the most

  9. NRMC - A GPU code for N-Reverse Monte Carlo modeling of fluids in confined media

    NASA Astrophysics Data System (ADS)

    Sánchez-Gil, Vicente; Noya, Eva G.; Lomba, Enrique

    2017-08-01

    NRMC is a parallel code for performing N-Reverse Monte Carlo modeling of fluids in confined media [V. Sánchez-Gil, E.G. Noya, E. Lomba, J. Chem. Phys. 140 (2014) 024504]. This method is an extension of the usual Reverse Monte Carlo method to obtain structural models of confined fluids compatible with experimental diffraction patterns, specifically designed to overcome the problem of slow diffusion that can appear under conditions of tight confinement. Most of the computational time in N-Reverse Monte Carlo modeling is spent in the evaluation of the structure factor for each trial configuration, a calculation that can be easily parallelized. Implementation of the structure factor evaluation in NVIDIA® CUDA so that the code can be run on GPUs leads to a speed up of up to two orders of magnitude.

  10. CaFe interstellar clouds

    NASA Astrophysics Data System (ADS)

    Bondar, A.; Kozak, M.; Gnaciński, P.; Galazutdinov, G. A.; Beletsky, Y.; Krełowski, J.

    2007-07-01

    A new kind of interstellar cloud is proposed. These are rare (just a few examples among ~300 lines of sight) objects with the CaI 4227-Å, FeI 3720-Å and 3860-Å lines stronger than those of KI (near 7699 Å) and NaI (near 3302 Å). We propose the name `CaFe' for these clouds. Apparently they occupy different volumes from the well-known interstellar HI clouds where the KI and ultraviolet NaI lines are dominant features. In the CaFe clouds we have not found either detectable molecular features (CH, CN) or diffuse interstellar bands which, as commonly believed, are carried by some complex, organic molecules. We have found the CaFe clouds only along sightlines toward hot, luminous (and thus distant) objects with high rates of mass loss. In principle, the observed gas-phase interstellar abundances reflect the combined effects of the nucleosynthetic history of the material, the depletion of heavy elements into dust grains and the ionization state of these elements which may depend on irradiation by neighbouring stars. Based on data collected using the Maestro spectrograph at the Terskol 2-m telescope, Russia; and on data collected using the ESO Feros spectrograph; and on data obtained from the ESO Science Archive Facility acquired with the UVES spectrograph, Chile. E-mail: `arctur'@rambler.ru (AB); marizak@astri.uni.torun.pl (MK); pg@iftia.univ.gda.pl (PG); gala@boao.re.kr (GAG); ybialets@eso.org (YB); jacek@astri.uni.torun.pl (JK)

  11. Cancer heterogeneity and multilayer spatial evolutionary games.

    PubMed

    Świerniak, Andrzej; Krześlak, Michał

    2016-10-13

    Evolutionary game theory (EGT) has been widely used to simulate tumour processes. In almost all studies on EGT models analysis is limited to two or three phenotypes. Our model contains four main phenotypes. Moreover, in a standard approach only heterogeneity of populations is studied, while cancer cells remain homogeneous. A multilayer approach proposed in this paper enables to study heterogeneity of single cells. In the extended model presented in this paper we consider four strategies (phenotypes) that can arise by mutations. We propose multilayer spatial evolutionary games (MSEG) played on multiple 2D lattices corresponding to the possible phenotypes. It enables simulation and investigation of heterogeneity on the player-level in addition to the population-level. Moreover, it allows to model interactions between arbitrary many phenotypes resulting from the mixture of basic traits. Different equilibrium points and scenarios (monomorphic and polymorphic populations) have been achieved depending on model parameters and the type of played game. However, there is a possibility of stable quadromorphic population in MSEG games for the same set of parameters like for the mean-field game. The model assumes an existence of four possible phenotypes (strategies) in the population of cells that make up tumour. Various parameters and relations between cells lead to complex analysis of this model and give diverse results. One of them is a possibility of stable coexistence of different tumour cells within the population, representing almost arbitrary mixture of the basic phenotypes. This article was reviewed by Tomasz Lipniacki, Urszula Ledzewicz and Jacek Banasiak.

  12. Conical : An extended module for computing a numerically satisfactory pair of solutions of the differential equation for conical functions

    NASA Astrophysics Data System (ADS)

    Dunster, T. M.; Gil, A.; Segura, J.; Temme, N. M.

    2017-08-01

    Conical functions appear in a large number of applications in physics and engineering. In this paper we describe an extension of our module Conical (Gil et al., 2012) for the computation of conical functions. Specifically, the module includes now a routine for computing the function R-1/2+ iτ m (x) , a real-valued numerically satisfactory companion of the function P-1/2+ iτ m (x) for x > 1. In this way, a natural basis for solving Dirichlet problems bounded by conical domains is provided. The module also improves the performance of our previous algorithm for the conical function P-1/2+ iτ m (x) and it includes now the computation of the first order derivative of the function. This is also considered for the function R-1/2+ iτ m (x) in the extended algorithm.

  13. ANNOTATION TAKEN, IN THE PERSPECTIVE OF CRIMINAL AND CONSTITUTIONAL LAW, AS WELL AS IN CRIMINOLOGY, TO THE DECISION OF THE PORTUGUESE CONSTITUTIONAL COURT, OF JANUARY 13, 2011--WITH RESPECT TO THE PROBLEMS OF "CONSENT" AND "MEDICAL ACT".

    PubMed

    Bandeira, Gonçalo S de Melo

    2014-07-01

    1--Summary of the decision taken by the Portuguese Constitutional Court, of January 13, 2011; 2--Complete text of the decision of the Portuguese Constitutional Court, of January 13, 2011, Judge Maria João ANTUNES (Reporter), Judge Carlos Pamplona de OLIVEIRA, Judge José Borges SOEIRO, Judge Gil GALVÃO, Judge Rui Manuel Moura RAMOS (President)--in terms of the appositive declaration to the sentence n. 487/2010: t.c.http://www. tribunalconstitucional.pt, August 1, 2011; 3--Brief annotation to the problem of the "medical act"; 3.1--Plus some conclusions on the brief annotation to the problem of the "medical act"; 3.2--Brief annotation to the problem of "consent"--continuation of the previous comments; 4--Conclusions. It must never be forgotten that "consent" does not stand as the only cause of exclusion of unlawfulness.

  14. Spotlight on nano-theranostics in South Korea: applications in diagnostics and treatment of diseases.

    PubMed

    Lee, Sangwha; Kim, Jongsung; Bark, Chung Wung; Lee, Bonghee; Ju, Heongkyu; Kang, Se Chan; Kim, TaeYoung; Kim, Moon Il; Ko, Young Tag; Nam, Jeong-Seok; Yoon, Hyon Hee; Yun, Kyu-Sik; Yoon, Young Soo; An, Seong Soo A; Hulme, John

    2015-01-01

    From the synergistic integration and the multidisciplinary strengths of the BioNano Sensor Research Center, Gachon Bionano Research Institute, and Lee Gil Ya Cancer and Diabetes Institute, researchers, students, and faculties at Gachon University in collaboration with other institutions in Korea, Australia, France, America, and Japan have come together to produce a special issue on the diverse applications of nano-theranostics in nanomedicine. This special issue will showcase new research conducted by various scientific groups in Gyonggi-do and Songdo/Incheon, South Korea. The objectives of this special issue are as follows: 1) to bring together and demonstrate some of the latest research results in the field, 2) to introduce new multifunctional nanomaterials and their applications in imaging and detection methods, and 3) to stimulate collaborative interdisciplinary research at both national and international levels in nanomedicine.

  15. Spotlight on nano-theranostics in South Korea: applications in diagnostics and treatment of diseases

    PubMed Central

    Lee, Sangwha; Kim, Jongsung; Bark, Chung Wung; Lee, Bonghee; Ju, Heongkyu; Kang, Se Chan; Kim, TaeYoung; Kim, Moon Il; Ko, Young Tag; Nam, Jeong-Seok; Yoon, Hyon Hee; Yun, Kyu-Sik; Yoon, Young Soo; An, Seong Soo A; Hulme, John

    2015-01-01

    From the synergistic integration and the multidisciplinary strengths of the BioNano Sensor Research Center, Gachon Bionano Research Institute, and Lee Gil Ya Cancer and Diabetes Institute, researchers, students, and faculties at Gachon University in collaboration with other institutions in Korea, Australia, France, America, and Japan have come together to produce a special issue on the diverse applications of nano-theranostics in nanomedicine. This special issue will showcase new research conducted by various scientific groups in Gyonggi-do and Songdo/Incheon, South Korea. The objectives of this special issue are as follows: 1) to bring together and demonstrate some of the latest research results in the field, 2) to introduce new multifunctional nanomaterials and their applications in imaging and detection methods, and 3) to stimulate collaborative interdisciplinary research at both national and international levels in nanomedicine. PMID:26345737

  16. Clinical features and management of facial nerve paralysis in children: analysis of 24 cases.

    PubMed

    Cha, H E; Baek, M K; Yoon, J H; Yoon, B K; Kim, M J; Lee, J H

    2010-04-01

    To evaluate the causes, treatment modalities and recovery rate of paediatric facial nerve paralysis. We analysed 24 cases of paediatric facial nerve paralysis diagnosed in the otolaryngology department of Gachon University Gil Medical Center between January 2001 and June 2006. The most common cause was idiopathic palsy (16 cases, 66.7 per cent). The most common degree of facial nerve paralysis on first presentation was House-Brackmann grade IV (15 of 24 cases). All cases were treated with steroids. One of the 24 cases was also treated surgically with facial nerve decompression. Twenty-two cases (91.6 per cent) recovered to House-Brackmann grade I or II over the six-month follow-up period. Facial nerve paralysis in children can generally be successfully treated with conservative measures. However, in cases associated with trauma, radiological investigation is required for further evaluation and treatment.

  17. Delivering a MOOC for literature searching in health libraries: evaluation of a pilot project.

    PubMed

    Young, Gil; McLaren, Lisa; Maden, Michelle

    2017-12-01

    In an era when library budgets are being reduced, Massive Online Open Courses (MOOC's) can offer practical and viable alternatives to the delivery of costly face-to-face training courses. In this study, guest writers Gil Young from Health Care Libraries Unit - North, Lisa McLaren from Brighton and Sussex Medical School and Liverpool University PhD student Michelle Maden describe the outcomes of a funded project they led to develop a MOOC to deliver literature search training for health librarians. Funded by Health Education England, the MOOC was developed by the Library and Information Health Network North West as a pilot project that ran for six weeks. In particular, the MOOC target audience is discussed, how content was developed for the MOOC, promotion and participation, cost-effectiveness, evaluation, the impact of the MOOC and recommendations for future development. H. S. © 2017 Health Libraries Group.

  18. Theoretical Investigation of the Reactivity of Sodium Dicyanamide with Nitric Acid.

    PubMed

    Vogelhuber, Kristen M; Booth, Ryan S; Annesley, Christopher J

    2018-03-01

    There is a need to replace current hydrazine fuels with safer propellants, and dicyanamide (DCA - )-based systems have emerged as promising alternatives because they autoignite when mixed with some oxidizers. Previous studies of the hypergolic reaction mechanism have focused on the reaction between DCA - and the oxidizer HNO 3 ; here, we compare the calculated pathway of DCA - + HNO 3 with the reaction coordinate of the ion pair sodium dicyanamide with nitric acid, Na[DCA] + HNO 3 . Enthalpies and free energies are calculated in the gas phase and in solution using a quantum mechanical continuum solvation model, SMD-GIL. The barriers to the Na[DCA] + HNO 3 reaction are dramatically lowered relative to those of the reaction with the bare anion, and an exothermic exit channel to produce NaNO 3 and the reactive intermediate HDCA appears. These results suggest that Na[DCA] may accelerate the ignition reaction.

  19. [The progressive reduction of functioning in the course of mucopolysaccharidosis type IIIA - longitudinal study of two siblings].

    PubMed

    Michalska, Agata; Nawrocka, Małgorzata; Znój, Dorota

    2013-01-01

    This paper presents a description of changes in the functioning of two siblings diagnosed with mucopolysaccharidosis type III A. Both are under specialist care exercised by the Rehabilitation, Care and Education Centre in the city Kielce, including care of a oligophrenopedagogue, a psychologist, a speech therapist and a physiotherapist. Evaluation of changes in functioning of two siblings diagnosed with mucopolysaccharidosis type IIIA. The longitudinal study covered two children with MPS type IIIA. During the 29 months of observation, there were six measurements on the basis of PPAC Gunzburg Inventory in the Polish adaptation by Tadeusz Witkowski. The results are shown in the form of PPAC diagrams and profiles of functioning. Despite the differences in the presence and severity of somatic and neurocognitive symptoms, functioning both of the boy and the girl does not differ from functioning described in the literature. Therapeutic interventions have produced short-term improvements in its area of self-service, communication and activities. Despite the similar trend of changes in functioning, there is an inter-individual variability in the quality of patterns and dynamics of progress. The progressive decrease in the level of functioning in patients with MPS IIIA does not preclude the acquisition of new skills. They are not permanent, however. There is a need for functional assessment in order to learn more about the specificity of the disease and to assume an individualised therapeutic approach aimed at improving the quality of life of patients with MPS IIIA and, indirectly, the quality of life of their families.

  20. Role of banding in forest conservation strategy in eastern Guatemala

    USGS Publications Warehouse

    Robbins, C.S.; Dowell, B.A.; Arias, I.; Cerezo B., A.

    1999-01-01

    In response to a request from FUNDAECO, a Guatemalan non-government organization, we worked with them to develop a conservation strategy for the Cerro San Gil Protected Area and surrounding private lands. Volunteer banders from a dozen states and Canadian provinces assisted in long-term monitoring of populations of resident and migratory species through banding and point counts. Guatemalan students were trained to continue the research and initiate other conservation projects. Banding data helped demonstrate habitat and elevational affiliations, effects of habitat fragmentation, site fidelity, survival rates, local movements, and presence of rare species not otherwise detected. Banding was also an excellent teaching tool and provided videos for conservation programs on Guatemala national television. Roadside and off-road Breeding Bird Survey transects were used to map distribution of breeding species on habitat maps derived from satellite imagery, and point count surveys on private lands were used to identify prime habitats that warrant protection through conservation easements--a new concept for Central America.

  1. Centrosymmetric molecules as possible carriers of diffuse interstellar bands

    NASA Astrophysics Data System (ADS)

    Kaźmierczak, M.; Schmidt, M. R.; Galazutdinov, G. A.; Musaev, F. A.; Betelesky, Y.; Krełowski, J.

    2010-11-01

    In this paper, we present new data with interstellar C2 (Phillips bands A 1 Πu-X1 Σ+g), from observations made with the Ultraviolet-Visual Echelle Spectrograph of the European Southern Observatory. We have determined the interstellar column densities and excitation temperatures of C2 for nine Galactic lines. For seven of these, C2 has never been observed before, so in this case the still small sample of interstellar clouds (26 lines of sight), where a detailed analysis of C2 excitation has been made, has increased significantly. This paper is a continuation of previous works where interstellar molecules (C2 and diffuse interstellar bands) have been analysed. Because the sample of interstellar clouds with C2 has increased, we can show that the width and shape of the profiles of some diffuse interstellar bands (6196 and 5797 Å) apparently depend on the gas kinetic and rotational temperatures of C2; the profiles are broader because of the higher values of the gas kinetic and rotational temperatures of C2. There are also diffuse interstellar bands (4964 and 5850 Å) for which this effect does not exist. Based on observations made with ESO telescopes at the Paranal Observatory under programme IDs 266.D-5655(A), 67.C-0281(A), 71.C-0513(C), 67.D-0439(A) and 082.C-0566(A) and at La Silla under programme IDs 078.C-0403(A), 076.C-0164(A) and 073.C-0337(A). Also based on observations made with the 1.8-m telescope in South Korea and the 2-m telescope at the International Centre for Astronomical and Medico-Ecological Research, Terskol, Russia. E-mail: kazmierczak@astri.uni.torun.pl (MK); schmidt@ncac.torun.pl (MRS); runizag@gmail.com (GAG); ybialets@eso.org (YB); jacek@astri.uni.torun.pl (JK)

  2. The stable archipelago in the region of the Pallas and Hansa dynamical families

    NASA Astrophysics Data System (ADS)

    Carruba, V.

    2010-10-01

    Among highly inclined asteroids, the region of the central main belt between the 3J:-1A and 5J:-2A mean-motion resonances has long been known to host the Pallas and Hansa dynamical families. This region is characterized by the presence of the ν6,ν5 and ν16 secular resonances, which in conjunction with the 8J:-3A mean-motion resonance divide the area into eight regions, the stable islands of the archipelago. Using a set of proper elements available at the Asteroids Dynamic Site (AstDyS) at the time, Gil-Hutton identified a family around (686) Gersuind and two more minor clumps around (945) Barcelona and (148) Gallia in the space of synthetic proper elements. In this work I compute a new set of synthetic proper elements for 2310 numbered and 2142 multi-opposition objects in this region. The use of the frequency-modified Fourier transform method allowed me to obtain non-negative estimates of the proper frequency of argument of pericentre precession g for members of the Hansa families characterized by values of eforced larger than efree, and to solve the problem of the non-linear dependence of g versus n observed by Carruba & Michtchenko. My analysis shows that the two minor clumps of Gil-Hutton should now be considered dynamical families. Also, a new family in the domains of both proper elements (a, e, sini) and frequencies (n, g, g + s) around (1222) Tina is discovered in this work, as well as a new frequency family around (4203) Brucato. Nine minor clumps, one of which is visible in both domains, are also observed. The taxonomical analysis of family members suggests that the Pallas family is compatible with a B-type composition (but two members are classified as C interlopers), while the Hansa family is possibly an S-type one. Sloan Digital Sky Survey Moving Object Catalog (SDSS-MOC3) data suggest that the Barcelona family might be an Sq group, and the Gersuind, Gallia and Tina ones should belong to the S complex. Geometric albedo data seem to confirm the

  3. Breakdown characteristics of SF6/N2 in severely non-uniform electric fields at low temperatures

    NASA Astrophysics Data System (ADS)

    Wang, Y.; Gao, Z. W.; Li, G. X.; Zhu, X. C.; Yu, C. L.; Liang, J. Q.; Li, L.

    2018-01-01

    SF6 has good electrical insulating properties, which is widely used as an insulating medium of GIS, GIL and other electrical equipment. However, the reliability of electrical equipments´ insulated gas is greatly challenged in cold areas, since SF6 more readily liquefies. To solve the problem, SF6 can be mixed with N2 to maintain the insulating properties, and reduce its liquefaction temperature. Such practice has certain application prospect. In this paper, a breakdown experimental platform was built to study the insulating property of SF6/N2 at low temperature, wherein the temperature of the platform can be adjusted. A severely non-uniform electric field was generated by a rod-plate electrode. The breakdown characteristics of SF6/N2 with different mixing proportions at low pressures and low temperatures were measured. The result showed that the mixed gas was not liquefied within the temperature range. Temperature had insignificant influence on the insulating property thereof. The result in the paper has certain guiding significance for applying SF6/N2 mixed gas in high latitude areas.

  4. La edad de las familias Eos, Themis y Koronis

    NASA Astrophysics Data System (ADS)

    Gil-Hutton, R.

    Las familias de asteroides son el producto de la disrupción colisional de objetos destruídos por impactos ocurridos en el cinturón principal. Las colisiones posteriores han modificado los tamaños y las órbitas de los miembros de estas familias, por lo que las distribuciones que vemos hoy en día pueden ser muy diferentes de aquellas producidas inmediatamente después de la fragmentación del objeto original. En esta hipótesis, puede ser difícil reconstruir la evolución colisional de la familia basándose sólo en las actuales distribuciones y puede ser necesario hacer ciertas suposiciones para obtener información sobre las condiciones iniciales. En este trabajo se deriva una estimación de la edad de las familias Eos, Themis y Koronis obtenida de una simulación de la evolución colisional de un cuerpo original teórico para cada familia usando un modelo de distribución para el cinturón propuesto por Gil-Hutton (1996).

  5. Sociodemographic and health factors associated with mortality in community-dwelling elderly.

    PubMed

    Borim, Flávia Silva Arbex; Francisco, Priscila Maria Stolses Bergamo; Neri, Anita Liberalesso

    2017-05-04

    The objective of this study is to identify factors associated with mortality, with emphasis on gender and age differences. This is a cross-sectional study, which uses data from the FIBRA-2008-2009 network in Campinas, State of São Paulo, Brazil, with information on non-institutionalized residents of the urban area and the Mortality Information System. The dependent variable has been death, in 2013. The associations have been tested by odds ratio (OR) and their 95% confidence intervals, and the analyses have been conducted using the program Stata 12.0. Average age has been 72.3 years, 69.3% have been women, and 8.9% have died. We have found greater OR for mortality in individuals aged ≥ 75 years, classified as pre-frail or frail, and in those who have reported heart disease. In this study, the analysis of specific subgroups has allowed us to better understand the relationship between the factors associated with death in the elderly. With the exception of age, strategies based on primary and secondary care, focused on priority groups, can have a positive impact on the reduction of mortality among the elderly. Identificar fatores associados à mortalidade, com ênfase nas diferenças de gênero e idade. Trata-se de estudo transversal, utilizando dados provenientes da rede FIBRA-2008-2009 em Campinas, SP, com informações de pessoas não institucionalizadas residentes na área urbana e pelo Sistema de Informações de Mortalidade. A variável dependente foi a ocorrência de óbito, verificada em 2013. As associações foram testadas pelas razões de chances (OR) e respectivos intervalos de confiança de 95%, e as análises conduzidas no programa Stata 12.0. A média de idade foi 72,3 anos, 69,3% eram mulheres e 8,9% foram a óbito. Encontrou-se maior OR para mortalidade nos indivíduos com idade ≥ 75 anos, nos classificados como pré-frágil ou frágil e naqueles que referiram doença do coração. Neste estudo, a análise para os subgrupos específicos permitiu

  6. Determination of thiamine HCl and pyridoxine HCl in pharmaceutical preparations using UV-visible spectrophotometry and genetic algorithm based multivariate calibration methods.

    PubMed

    Ozdemir, Durmus; Dinc, Erdal

    2004-07-01

    Simultaneous determination of binary mixtures pyridoxine hydrochloride and thiamine hydrochloride in a vitamin combination using UV-visible spectrophotometry and classical least squares (CLS) and three newly developed genetic algorithm (GA) based multivariate calibration methods was demonstrated. The three genetic multivariate calibration methods are Genetic Classical Least Squares (GCLS), Genetic Inverse Least Squares (GILS) and Genetic Regression (GR). The sample data set contains the UV-visible spectra of 30 synthetic mixtures (8 to 40 microg/ml) of these vitamins and 10 tablets containing 250 mg from each vitamin. The spectra cover the range from 200 to 330 nm in 0.1 nm intervals. Several calibration models were built with the four methods for the two components. Overall, the standard error of calibration (SEC) and the standard error of prediction (SEP) for the synthetic data were in the range of <0.01 and 0.43 microg/ml for all the four methods. The SEP values for the tablets were in the range of 2.91 and 11.51 mg/tablets. A comparison of genetic algorithm selected wavelengths for each component using GR method was also included.

  7. Reversible capture of SO2 through functionalized ionic liquids.

    PubMed

    Yang, Dezhong; Hou, Minqiang; Ning, Hui; Ma, Jun; Kang, Xinchen; Zhang, Jianling; Han, Buxing

    2013-07-01

    Emission of SO2 in flue gas from the combustion of fossil fuels leads to severe environmental problems. Exploration of green and efficient methods to capture SO2 is an interesting topic, especially at lower SO2 partial pressures. In this work, ionic liquids (ILs) 1-(2-diethylaminoethyl)-3-methylimidazolium bis(trifluoromethylsulfonyl)imide ([Et2 NEMim][Tf2 N]) and 1-(2-diethylaminoethyl)-3-methylimidazolium tetrazolate ([Et2 NEMim][Tetz]) were synthesized. The performances of the two ILs to capture SO2 were studied under different conditions. It was demonstrated that the ILs were very efficient for SO2 absorption. The [Et2 NEMim][Tetz] IL designed in this work could absorb 0.47 g(SO2)g(IL)(-1) at 0.0101 MPa SO2 partial pressure, which is the highest capacity reported to date under the same conditions. The main reason for the large capacity was that both the cation and the anion could capture SO2 chemically. In addition, the IL could easily be regenerated, and the very high absorption capacity and rapid absorption/desorption rates were not changed over five repeated cycles. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Slow Photoelectron Spectroscopy and State-Selected Unimolecular Decomposition of Ionized DNA Bases Analogues

    NASA Astrophysics Data System (ADS)

    Mahjoub, Ahmed; Hochlaf, Majdi; Poisson, Lionel; Garcia, Gustavo A.; Nahon, Laurent

    2013-06-01

    We studied the single-photon ionization of gas-phase 2-Piperidone (DNA basis analogue) and of its dimer using vacuum-ultraviolet (VUV) synchrotron radiation coupled to a velocity map imaging electron/ion coincidence spectrometer The slow photoelectron spectrum (SPES) of the monomer is dominated by the vibrational transitions to the ground state. These spectra are assigned with the help of theoretical calculations dealing with the equilibrium geometries, electronic-state patterns and evolutions, harmonic and anharmonic wavenumbers. After its formation, dimer is subject of intramolecular isomerization, H transfer and then unimolecular fragmentation processes. The near threshold photofragmentation pattern of the cationic 2-Piperidone cation and its dimer has been recorded. The experimental method yields the fragment intensity as a function of the internal energy deposited into the parent cation. In parallel, ab initio studies on ionic and neutral fragmentation products have been performed with the aim of determining the isomers of the ionic products observed experimentally as well as of their neutral counterparts. L. Nahon, N. De Oliveria,J. F. Gil,B. Pilette,O. Marcouillé, B. La garde and F. Polack Journal of Synchrotron Radiation {19}(4), 508-520; 2012

  9. Resource Efficient Hardware Architecture for Fast Computation of Running Max/Min Filters

    PubMed Central

    Torres-Huitzil, Cesar

    2013-01-01

    Running max/min filters on rectangular kernels are widely used in many digital signal and image processing applications. Filtering with a k × k kernel requires of k 2 − 1 comparisons per sample for a direct implementation; thus, performance scales expensively with the kernel size k. Faster computations can be achieved by kernel decomposition and using constant time one-dimensional algorithms on custom hardware. This paper presents a hardware architecture for real-time computation of running max/min filters based on the van Herk/Gil-Werman (HGW) algorithm. The proposed architecture design uses less computation and memory resources than previously reported architectures when targeted to Field Programmable Gate Array (FPGA) devices. Implementation results show that the architecture is able to compute max/min filters, on 1024 × 1024 images with up to 255 × 255 kernels, in around 8.4 milliseconds, 120 frames per second, at a clock frequency of 250 MHz. The implementation is highly scalable for the kernel size with good performance/area tradeoff suitable for embedded applications. The applicability of the architecture is shown for local adaptive image thresholding. PMID:24288456

  10. Using Local Perturbations To Manipulate and Control Pointer States in Quantum Dot Systems

    NASA Astrophysics Data System (ADS)

    Akis, Richard; Speyer, Gil; Ferry, David; Brunner, Roland

    2012-02-01

    Recently, scanning gate microscopy (SGM) was used to image scarred wave functions in an open InAs quantum dot[1]. The SGM tip provides a local potential perturbation and imaging is performed by measuring changes in conductance. Scarred wave functions, long associated with quantum chaos, have been shown in open dots to correspond to pointer states[2], eigenstates that survive the decoherence process that occurs via coupling to the environment. Pointer states modulate the conductance, yielding periodic fluctuations and the scars, normally thought unstable, are stabilized by quantum Darwinism [3]. We shall show that, beyond probing, pointer states can be manipulated by local perturbations. Particularly interesting effects occur in coupled quantum dot arrays, where a pointer state localized in one dot can be shifted over into another with a perturbation in a completely different part of the system. These nonlocal effects may perhaps be exploited to give such systems an exotic functionality. [1] A. M. Burke, R. Akis, T. E. Day, Gil Speyer, D. K. Ferry, and B. R. Bennett, Phys. Rev. Lett. 104, 176801 (2010). [2] D. K. Ferry, R. Akis, and J. P. Bird, Phys. Rev. Lett. 104, 176801 (2004). [3] R. Brunner, R. Akis,D. K. Ferry, F. Kuchar,and R. Meisels, Phys. Rev. Lett. 101, 024102 (2008).

  11. Long term study of ixodid ticks feeding on red deer (Cervus elaphus) in a meso-Mediterranean climate.

    PubMed

    Valcárcel, F; González, J; Tercero Jaime, J M; Olmeda, A S

    2016-05-01

    Red deer (Cervus elaphus L.) are very valuable in trophy-hunting but also contribute to the preservation of natural areas. They are affected by many parasites and pathogens, including hard ticks that are not only important parasites themselves but can also act as vectors and/or reservoirs of pathogens. Tick phenology is complex insofar as population dynamics depend on environmental conditions, vegetation, host availability and their own intrinsic characteristic. Ticks were collected monthly from January 2007 to December 2014 from red deer on a natural reserve located in a meso-Mediterranean environment in Central Spain. A total of 8978 specimens of ixodid ticks were recovered with a mean Parasitization Index of 65.06 ticks/deer. Red deer were infected the whole year round with a summer-spring pattern and two secondary peaks in February and October. The main species was Hyalomma lusitanicum Koch followed by Rhipicephalus bursa Canestrini and Fanzago, Rhipicephalus pusillus Gil Collado, Dermacentor marginatus Sulzer and Ixodes ricinus L. Hyalomma lusitanicum has a complex life cycle in which several generations initiate their cycle at different times throughout the year, most probably lasting more than 1 year. We also describe the ability of nymphs to feed on large ungulates even though their habitual host is wild rabbit.

  12. Building on a solid foundation: SAR and QSAR as a fundamental strategy to reduce animal testing.

    PubMed

    Sullivan, K M; Manuppello, J R; Willett, C E

    2014-01-01

    The development of more efficient, ethical, and effective means of assessing the effects of chemicals on human health and the environment was a lifetime goal of Gilman Veith. His work has provided the foundation for the use of chemical structure for informing toxicological assessment by regulatory agencies the world over. Veith's scientific work influenced the early development of the SAR models in use today at the US Environmental Protection Agency. He was the driving force behind the Organisation for Economic Co-operation and Development QSAR Toolbox. Veith was one of a few early pioneers whose vision led to the linkage of chemical structure and biological activity as a means of predicting adverse apical outcomes (known as a mode of action, or an adverse outcome pathway approach), and he understood at an early stage the power that could be harnessed when combining computational and mechanistic biological approaches as a means of avoiding animal testing. Through the International QSAR Foundation he organized like-minded experts to develop non-animal methods and frameworks for the assessment of chemical hazard and risk for the benefit of public and environmental health. Avoiding animal testing was Gil's passion, and his work helped to initiate the paradigm shift in toxicology that is now rendering this feasible.

  13. FOREWORD: 7th Symposium on Vacuum-based Science and Technology (SVBST2013)

    NASA Astrophysics Data System (ADS)

    Gulbiński, W.

    2014-11-01

    These are the proceedings of the 7th Symposium on Vacuum based Science and Technology organized in Kołobrzeg (PL) on November 19-21, 2013 by the Institute of Technology and Education, Koszalin University of Technology and the Clausius Tower Society under auspices of the Polish Vacuum Society (PTP) and the German Vacuum Society (DVG) and in collaboration with the BalticNet PlasmaTec and the Society of Vacuum Coaters (SVC). It was accompanied by the 12-th Annual Meeting of the German Vacuum Society. The mission of the Symposium is to provide a forum for presentation and exchange of expertise and research results in the field of vacuum and plasma science. After already six successful meetings organized alternately in Poland and Germany our goal is to continue and foster cooperation within the vacuum and plasma science community. This year, the Rudolf-Jaeckel Prize, awarded by the DVG for outstanding achievements in the field of vacuum based sciences, was presented to Dr Ute Bergner, president of the VACOM Vakuum Komponenten & Messtechnik GmbH and a member of our community. The full-day course organized in the framework of the Educational Program by the Society of Vacuum Coaters (SVC) and entitled: An Introduction to Physical Vapor Deposition (PVD) Processes was held on November 18, 2013 as a satellite event of the Symposium. The instructor was Prof. Ismat Shah from Delaware University (US). The Clausius Session, already traditionally organized during the Symposium was addressed this year to young generation. We invited our young colleagues to attend a series of educational lectures reporting on achievements in graphene science, scanning probe microscopy and plasma science. Lectures were given by: Prof. Jacek Baranowski from the Institute of Electronic Materials Technology in Warsaw, Prof. Teodor Gotszalk from the Wroclaw University of Technology and Prof. Holger Kersten from the Christian Albrechts University in Kiel. The Symposium was accompanied by an industry

  14. Zika in Twitter: Temporal Variations of Locations, Actors, and Concepts.

    PubMed

    Stefanidis, Anthony; Vraga, Emily; Lamprianidis, Georgios; Radzikowski, Jacek; Delamater, Paul L; Jacobsen, Kathryn H; Pfoser, Dieter; Croitoru, Arie; Crooks, Andrew

    2017-04-20

    contributes to advancing our understanding of social media discourse during a public health emergency of international concern. ©Anthony Stefanidis, Emily Vraga, Georgios Lamprianidis, Jacek Radzikowski, Paul L Delamater, Kathryn H Jacobsen, Dieter Pfoser, Arie Croitoru, Andrew Crooks. Originally published in JMIR Public Health and Surveillance (http://publichealth.jmir.org), 20.04.2017.

  15. A Study on New Song of the Sky Pacers

    NASA Astrophysics Data System (ADS)

    Ahn, Sang-Hyeon

    2009-12-01

    We investigated `Song of the Sky Pacers, Adopted to the New Methods' (新法步天歌), the latest version of Joseon's `Song of the Sky Pacers' (步天歌). Due to the influence of new knowledge on Chinese asterisms imported from the Ching dynasty, `Song of the Sky Pacers with New Star-Charts' was written in the eighteenth century. However, the disagreement between song and star-charts was causing confusion in practical applications such as Joseon's national examination for selecting astronomers. In order to improve this situation, Royal Observatory of the Joseon dynasty (觀象監) published `Song of the Sky Pacers, Adopted to the New Methods' based upon star-charts and song in the Sequel of I-Hsiang-K'ao-ch'eng (欽定儀象考成續編). The New Song was edited by a middle-class professional astronomer Yi Jun-yang (李俊養), and corrected by a nobleman Nam Byeong-gil (南秉吉). We establish a brief biography of Yi Jun-yang. The New Song preserves the genuine characteristics of previous Joseon's Song including the format of title of each lunar mansion and description on the location of the Milky Way in the asterisms. The description of the Milky Way was newly written based on the data in volume 31 and 32 of the Sequel of I-Hsiang-K'ao-ch'eng.

  16. Dialogue as a tool for meaning making

    NASA Astrophysics Data System (ADS)

    Bruni, Angela Suzanne Dudley

    In order to empower citizens to analyze the effects, risk, and value of science, a knowledge of scientific concepts is necessary (Mejlgaard, 2009). The formal educational system plays a role in this endeavor (Gil-Perez & Vilches, 2005). One proposed constructivist practice is the use of social learning activities using verbalized, shared cognition among learners. In an effort to investigate the effects of verbally shared cognition, this project sought to determine if social learning opportunities affect the mastery of content in gateway biology courses and to identify the types of dialogue students engage in during cognitive collaboration. Fifty-seven students enrolled in a small southern community college were randomly assigned into treatment groups for each of nine units of instruction. The treatment variable was participation in verbalized social learning activities. Treatment differences based on a pretest/posttest design were analyzed using various statistical methods and recorded student discussions were analyzed for characteristics of talk based on a model developed by Mercer. Findings support the use of social learning activities as a way to improve content knowledge. Students in the treatment group had higher posttest and gain scores than those in the control group, with statistical significance reached in some cases. Types of talk were examined to support the constructivist method of learning. Findings support the use of non-confrontational talk as the vector of meaning making within the classroom.

  17. Validation and reliability of a Behcet's Syndrome Activity Scale in Korea.

    PubMed

    Choi, Hyo Jin; Seo, Mi Ryoung; Ryu, Hee Jung; Baek, Han Joo

    2016-01-01

    We prepared a cross-cultural adaptation of the Behcet's Syndrome Activity Scale (BSAS) and evaluated its reliability and validity in Korea. Fifty patients with Behcet's disease (BD) who attended the Rheumatology Clinic of Gachon University Gil Medical Center were included in this study. The first BSAS questionnaire was administered at each clinic visit, and the second questionnaire was completed at home within 24 hours of the visit. A Behcet's Disease Current Activity Form (BDCAF) and a Behcet's Disease Quality of Life (BDQOL) form were also given to patients. The test-retest reliability was analyzed by intraclass correlation coefficients (ICC). To assess the validity, the total BSAS score was compared with the BDCAF score, the patient/physician global assessment, and the BDQOL by Spearman rank correlation. Twelve males and 38 females were enrolled. The mean age was 48.5 years and the mean disease duration was 6.7 years. Thirty-eight patients (76.0%) returned the questionnaire by mail. For the test-retest reliability, the two assessments were significantly correlated on all 10 items of the BSAS questionnaire (p < 0.05) and the total BSAS score (ICC, 0.925; p < 0.001). The total BSAS score was statistically correlated with the BDQOL, BDCAF, and patient/physician global assessment (p < 0.01). The Korean version of BSAS is a reliable and valid instrument to measure BD activity.

  18. Redescription of Chabaudacuaria multispinosa (Pérez Vigueras, 1938) n. g., n. comb. (Nematoda: Spirurida: Acuariidae) based on specimens from Ardea herodias L. and Nyctanassa violacea (L.) (Ardeidae) in Florida.

    PubMed

    Mutafchiev, Yasen; Kinsella, John M

    2012-10-01

    Chabaudacuaria n. g. is erected, as monotypic, for C. multispinosa (Pérez Vigueras, 1938) n. comb. (Spirurida: Acuariidae) [syns Cheilospirura multispinosa Pérez Vigueras, 1938; Acuaria multispinosa (Pérez Vigueras, 1938) Yamaguti, 1961]. This species, a parasite of various ardeid birds, is redescribed by means of light and scanning electron microscopy based on material from great blue herons Ardea herodias L. and yellow-crowned night herons Nyctanassa violacea (L.) in Florida, USA. Chabaudacuaria n. g. resembles Acuaria Bremser, 1811, Cheilospirura Diesing, 1861, Skrjabinocerca Schikhobalova, 1930 and Xenocordon Mawson, 1982 in its straight cordons which do not anastomose. However, it can be distinguished from them by the didelphic-prodelphic uterus and the absence of caudal alae in the males. In the pattern of its cordons (consisting of a row of plates and a longitudinal ridge) and the absence of an area rugosa, the new genus is similar to Chevreuxia Seurat, 1918, Syncuaria Gil'bert, 1927, Aviculariella Wehr, 1931, Skrjabinocara Kurashvili, 1940, Decorataria Sobolev, 1949 and Desportesius Chabaud & Campana, 1949, which are characterised by anastomosing cordons. The didelphic-prodelphic female reproductive system of Chabaudacuaria is intermediate between the didelphic-amphidelphic uterus of Chevreuxia and the monodelphic-prodelphic uterus of Syncuaria, Aviculariella, Skrjabinocara, Desportesius and Decorataria. Therefore, the straight and non-anastomosing cordons are considered to be autapomorphic for Chabaudacuaria.

  19. VSDMIP 1.5: an automated structure- and ligand-based virtual screening platform with a PyMOL graphical user interface.

    PubMed

    Cabrera, Álvaro Cortés; Gil-Redondo, Rubén; Perona, Almudena; Gago, Federico; Morreale, Antonio

    2011-09-01

    A graphical user interface (GUI) for our previously published virtual screening (VS) and data management platform VSDMIP (Gil-Redondo et al. J Comput Aided Mol Design, 23:171-184, 2009) that has been developed as a plugin for the popular molecular visualization program PyMOL is presented. In addition, a ligand-based VS module (LBVS) has been implemented that complements the already existing structure-based VS (SBVS) module and can be used in those cases where the receptor's 3D structure is not known or for pre-filtering purposes. This updated version of VSDMIP is placed in the context of similar available software and its LBVS and SBVS capabilities are tested here on a reduced set of the Directory of Useful Decoys database. Comparison of results from both approaches confirms the trend found in previous studies that LBVS outperforms SBVS. We also show that by combining LBVS and SBVS, and using a cluster of ~100 modern processors, it is possible to perform complete VS studies of several million molecules in less than a month. As the main processes in VSDMIP are 100% scalable, more powerful processors and larger clusters would notably decrease this time span. The plugin is distributed under an academic license upon request from the authors. © Springer Science+Business Media B.V. 2011

  20. Modeling precursor diffusion and reaction of atomic layer deposition in porous structures

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Keuter, Thomas, E-mail: t.keuter@fz-juelich.de; Menzler, Norbert Heribert; Mauer, Georg

    2015-01-01

    Atomic layer deposition (ALD) is a technique for depositing thin films of materials with a precise thickness control and uniformity using the self-limitation of the underlying reactions. Usually, it is difficult to predict the result of the ALD process for given external parameters, e.g., the precursor exposure time or the size of the precursor molecules. Therefore, a deeper insight into ALD by modeling the process is needed to improve process control and to achieve more economical coatings. In this paper, a detailed, microscopic approach based on the model developed by Yanguas-Gil and Elam is presented and additionally compared with themore » experiment. Precursor diffusion and second-order reaction kinetics are combined to identify the influence of the porous substrate's microstructural parameters and the influence of precursor properties on the coating. The thickness of the deposited film is calculated for different depths inside the porous structure in relation to the precursor exposure time, the precursor vapor pressure, and other parameters. Good agreement with experimental results was obtained for ALD zirconiumdioxide (ZrO{sub 2}) films using the precursors tetrakis(ethylmethylamido)zirconium and O{sub 2}. The derivation can be adjusted to describe other features of ALD processes, e.g., precursor and reactive site losses, different growth modes, pore size reduction, and surface diffusion.« less

  1. Dependence of Polarization of the near-Earth Asteroids (1036) Ganymed and (5143) Heracles on Wavelength and Phase Angle

    NASA Astrophysics Data System (ADS)

    Maleszewski, C.; McMillan, R.; Smith, P.

    2012-12-01

    We are measuring the polarization of asteroids with the SPOL polarimeter of Steward Observatory. With monthly access to the instrument, we can obtain many observations throughout phase angle. This is in contrast to other recent work that had to rely on aggregate properties of targets of similar taxonomic type. Comparing individual objects to these aggregate results may reveal differences of regolith properties from object to object. Both the phase angle and spectral dependence of polarization are being measured. SPOL provides simultaneous coverage from 0.40-0.75 microns, equivalent to BVR filters. Three phase curves thus reveal differences of phase angle dependences with respect to wavelength. The spectral dependence of the linear polarization is determined according to a linear trend previously used to describe the dependence for Main Belt Asteroids (MBAs) in various taxonomic classes (Belskaya et al. 2009). The slopes of these linear trends vs. phase angle are also investigated as was also done in the Belskaya analysis for MBAs in the C-, M-, and S-types. Two initial objects of interest are the NEAs (1036) Ganymed and (5143) Heracles. The taxonomic types of Ganymed and Heracles are S-type and Q-type respectively (DeMeo et al. 2009). For Ganymed, twelve observations were made between 2011 September and 2012 March. These include observations below ten degrees phase angle, which are currently lacking in the polarimetric databases. The positive branch of Ganymed's polarization phase curve behaved similarly across SPOL's wavelength range. But for wavelengths associated with a typical B-filter, the negative branch is more shallow and narrow. The negative phase branch of Ganymed is smaller compared to the aggregate phase curve of S-types determined by Gil-Hutton and Cañada-Assandri (2011). The linear polarization decreases with increasing wavelength at all observed phase angles. As the phase angle increases, the slope of the wavelength dependence of polarization

  2. USD Catalysis Group for Alternative Energy - Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hoefelmeyer, James

    2014-10-03

    I. Project Summary Catalytic processes are a major technological underpinning of modern society, and are essential to the energy sector in the processing of chemical fuels from natural resources, fine chemicals synthesis, and energy conversion. Advances in catalyst technology are enormously valuable since these lead to reduced chemical waste, reduced energy loss, and reduced costs. New energy technologies, which are critical to future economic growth, are also heavily reliant on catalysts, including fuel cells and photo-electrochemical cells. Currently, the state of South Dakota is underdeveloped in terms of research infrastructure related to catalysis. If South Dakota intends to participate inmore » significant economic growth opportunities that result from advances in catalyst technology, then this area of research needs to be made a high priority for investment. To this end, a focused research effort is proposed in which investigators from The University of South Dakota (USD) and The South Dakota School of Mines and Technology (SDSMT) will contribute to form the South Dakota Catalysis Group (SDCG). The multidisciplinary team of the (SDCG) include: (USD) Dan Engebretson, James Hoefelmeyer, Ranjit Koodali, and Grigoriy Sereda; (SDSMT) Phil Scott Ahrenkiel, Hao Fong, Jan Puszynski, Rajesh Shende, and Jacek Swiatkiewicz. The group is well suited to engage in a collaborative project due to the resources available within the existing programs. Activities within the SDCG will be monitored through an external committee consisting of three distinguished professors in chemistry. The committee will provide expert advice and recommendations to the SDCG. Advisory meetings in which committee members interact with South Dakota investigators will be accompanied by individual oral and poster presentations in a materials and catalysis symposium. The symposium will attract prominent scientists, and will enhance the visibility of research in the state of South Dakota. The SDCG

  3. Validation and reliability of a Behcet’s Syndrome Activity Scale in Korea

    PubMed Central

    Choi, Hyo Jin; Seo, Mi Ryoung; Ryu, Hee Jung; Baek, Han Joo

    2016-01-01

    Background/Aims: We prepared a cross-cultural adaptation of the Behcet’s Syndrome Activity Scale (BSAS) and evaluated its reliability and validity in Korea. Methods: Fifty patients with Behcet’s disease (BD) who attended the Rheumatology Clinic of Gachon University Gil Medical Center were included in this study. The first BSAS questionnaire was administered at each clinic visit, and the second questionnaire was completed at home within 24 hours of the visit. A Behcet’s Disease Current Activity Form (BDCAF) and a Behcet’s Disease Quality of Life (BDQOL) form were also given to patients. The test-retest reliability was analyzed by intraclass correlation coefficients (ICC). To assess the validity, the total BSAS score was compared with the BDCAF score, the patient/physician global assessment, and the BDQOL by Spearman rank correlation. Results: Twelve males and 38 females were enrolled. The mean age was 48.5 years and the mean disease duration was 6.7 years. Thirty-eight patients (76.0%) returned the questionnaire by mail. For the test-retest reliability, the two assessments were significantly correlated on all 10 items of the BSAS questionnaire (p < 0.05) and the total BSAS score (ICC, 0.925; p < 0.001). The total BSAS score was statistically correlated with the BDQOL, BDCAF, and patient/physician global assessment (p < 0.01). Conclusions: The Korean version of BSAS is a reliable and valid instrument to measure BD activity. PMID:26767871

  4. [Health Campaigns Against Malaria in Spain through the Specialized Journalism in Spain (1929-1954)].

    PubMed

    Barón Cano, Natalia; Mosquera Gordillo, Miguel Armando; Ballester Añón, Rosa

    2016-06-07

    Malaria was one of the most important public health problems of the Colonial Medicine and, for this reason, the subject was reflected in the Spanish medical journalism. The aim of the paper was to reconstruct the Spanish contributions to international health during the first half of the twentieth century. The primary sources of information on malaria were the medical journals Medicina de los Países Cálidos and Medicina Colonial, between 1929 and 1954. The documents were classified according to the sections of the magazine and its contents were studied, framing them in the history of international public health. In primary sources were found 466 documents. Malaria was one of the major diseases of the Spanish Protectorate in Morocco and Spanish Guinea, favoured by the occupation of the Spanish army. Antimalaria campaigns included strategies such as the use of Dichloro-diphenyl-trichloroethane, preventive education and massive quininización. Malariology in the specialized journalism, experienced a growing boom. The most outstanding authors in magazines analyzed were Gustavo Pittaluga, Sadí de Buen, Eliseo de Buen and Juan Gil-Collado. The Spanish specialized journalism provides the importance e interaction in antimalaria campaigns in Spain and Spanish African colonies of scientific, professional, political and military factors. The colonial situation was negative and marked differences between metropolis and colonies in terms of the effort, efficiency and the different temporal sequence of the measures undertaken.

  5. Isolation and characterization of an oxidosqualene cyclase gene encoding a β-amyrin synthase involved in Polygala tenuifolia Willd. saponin biosynthesis.

    PubMed

    Jin, Mei Lan; Lee, Dae Young; Um, Yurry; Lee, Jeong Hoon; Park, Chun Geun; Jetter, Reinhard; Kim, Ok Tae

    2014-03-01

    Expression of PtBS (Polygala tenuifolia β-amyrin synthase) led to the production of β-amyrin as sole product. Polygala tenuifolia Willdenow is a rich source of triterpene saponins, onjisaponins and polygalasaponins, used as herbal medicine to treat phlegms and for detumescence in traditional Asian healing. The Polygala saponins share the oleanane backbone structure and are, therefore, likely synthesized via β-amyrin as a common precursor. We hypothesized that, in analogy to diverse other plant species, this central intermediate should be formed by a β-amyrin synthase catalyzing the complex cyclization of oxidosqualene. This member of the oxidosqualene cyclase (OSC) family of enzymes is thus defining an important branch point between primary and secondary metabolisms, and playing a crucial role in the control of oleanane-type triterpene saponin biosynthesis. From P. tenuifolia roots, we isolated an OSC cDNA containing a reading frame of 2,289 bp nucleotides. The predicted protein of 763 amino acids (molecular weight 87.353 kDa) showed particularly high amino acid sequence identities to known β-amyrin synthases (85-87 %) and was, therefore, named PtBS. Expression of PtBS in the triterpenoid synthase-deficient yeast mutant GIL77 led to the production of β-amyrin as sole product. qRT-PCR analysis of various P. tenuifolia organs showed that PtBS transcript levels were highest in the roots, consistent with onjisaponin accumulation patterns. Therefore, we conclude that PtBS is the β-amyrin synthase enzyme catalyzing the first committed step in the biosynthesis of onjisaponins and polygalasaponins in P. tenuifolia.

  6. Discovery of a Satellite to Asteroid Family Member (702) Alauda

    NASA Astrophysics Data System (ADS)

    Margot, Jean-Luc; Rojo, P.

    2007-10-01

    Rojo and Margot [1] reported the discovery of a satellite to (702) Alauda from adaptive-optics imaging with the European Southern Observatory (ESO) 8-m Very Large Telescope (VLT) on Cerro Paranal, Chile. (702) Alauda (a = 3.2 AU, e = 0.02, i = 21 deg) has been identified as the largest member of a dynamical family [2,3], suggesting a possible origin of the satellite in the family formation event. The diameter of (702) Alauda is given in the IRAS Minor Planet Survey (IMPS) as 194.73 +/- 3.2 km [4]. If the primary and secondary have similar albedoes, the diameter of the satellite is about 5.5 km. This is based on the measured flux ratio between primary and secondary of 1250, possibly the largest ever observed for solar system binaries with adaptive optics. This is the first satellite discovered to a large minor planet of type B in the SMASSII taxonomy, which is defined by a linear featureless spectrum with bluish to neutral slope [5]. B-types are carbonaceous asteroids that are not well characterized. The mass and density estimates of B-type (2) Pallas vary by 50% [6,7]. Our ongoing determination of the satellite orbit will provide mass and density estimates for (702) Alauda. [1] Rojo and Margot, CBET 1016, 2007. [2] Foglia and Masi 2004, Minor Planet Bull. 41, 100. [3] Gil-Hutton 2006, Icarus 183, 93. [4] Tedesco 2002, AJ 123, 1056. [5] Bus and Binzel 2002, Icarus 158, 146. [6] Hilton 2002, Asteroids III, 103. [7] Britt et al. 2002, Asteroids III, 485.

  7. An Image-Based Modeling Experience about Social Facilities, Built during the Fascist Period in Middle Italy

    NASA Astrophysics Data System (ADS)

    Rossi, D.

    2011-09-01

    The main focus of this article is to explain a teaching activity. This experience follows a research aimed to testing innovative systems for formal and digital analysis of architectural building. In particular, the field of investigation is the analytical drawing. An analytical draw allows to develope an interpretative and similar models of reality; these models are built using photomodeling techniques and are designed to re-write modern and contemporary architecture. The typology of the buildings surveyed belong to a cultural period, called Modern Movement, historically placed between the two world wars. The Modern Movement aimed to renew existing architectural principle and to a functional redefinition of the same one. In Italy these principles arrived during the Fascist period. Heritage made up of public social buildings (case del Balilla, G.I.L., recreation center...) built during the fascist period in middle Italy is remarkable for quantity and in many cases for architectural quality. This kind of buildings are composed using pure shapes: large cube (gyms) alternate with long rectangular block containing offices creates compositions made of big volumes and high towers. These features are perfectly suited to the needs of a surveying process by photomodeling where the role of photography is central and where there is the need to identify certain and easily distinguishable points on all picture, leaning on the edges of the volume or lininig on the texture discontinuity. The goal is the documentation to preserve and to develop buildings and urban complexes of modern architecture, directed to encourage an artistic preservation.

  8. Competence and the Evolutionary Origins of Status and Power in Humans.

    PubMed

    Chapais, Bernard

    2015-06-01

    In this paper I propose an evolutionary model of human status that expands upon an earlier model proposed by Henrich and Gil-White Evolution and Human Behavior, 22,165-196 (2001). According to their model, there are two systems of status attainment in humans-"two ways to the top": the dominance route, which involves physical intimidation, a psychology of fear and hubristic pride, and provides coercive power, and the prestige route, which involves skills and knowledge (competence), a psychology of attraction to experts and authentic pride, and translates mainly into influence. The two systems would have evolved in response to different selective pressures, with attraction to experts serving a social learning function and coinciding with the evolution of cumulative culture. In this paper I argue that (1) the only one way to the top is competence because dominance itself involves competence and confers prestige, so there is no such thing as pure dominance status; (2) dominance in primates has two components: a competitive one involving physical coercion and a cooperative one involving competence-based attraction to high-ranking individuals (proto-prestige); (3) competence grants the same general type of power (dependence-based) in humans and other primates; (4) the attractiveness of high rank in primates is homologous with the admiration of experts in humans; (5) upon the evolution of cumulative culture, the attractiveness of high rank was co-opted to generate status differentials in a vast number of culturally generated domains of activity. I also discuss, in this perspective, the origins of hubristic pride, authentic pride, and nonauthoritarian leadership.

  9. The PANGAEA study design - a prospective, multicenter, non-interventional, long-term study on fingolimod for the treatment of multiple sclerosis in daily practice.

    PubMed

    Ziemssen, Tjalf; Kern, Raimar; Cornelissen, Christian

    2015-06-18

    Fingolimod (Gilenya) is an oral medication for patients with highly active relapsing-remitting Multiple Sclerosis (RRMS). Clinical trials and post-marketing experience on more than 114,000 patients have established a detailed safety profile. Total patient exposure now exceeds 195,000 patient-years as stated in the last financial report (Dec 2014) of the Novartis Pharma AG, Basel, Switzerland. However, less is known about the safety of long-term fingolimod use in daily practice. Here, we describe the study design of PANGAEA (Post-Authorization Non-interventional German sAfety of GilEnyA in RRMS patients), a prospective, multicenter, non-interventional, long-term study to collect safety, efficacy, and pharmacoeconomic data on RRMS patients treated with fingolimod (0.5 mg/daily) under real-world conditions in Germany. PANGAEA is striving to assess a real-world safety and efficacy profile of fingolimod, based on data from 4,000 RRMS patients, obtained during a 60-month observational phase. A pharmacoeconomic sub-study of 800 RRMS patients further collects patient-reported outcome measures of disability, quality of life, compliance, treatment satisfaction, and usage of resources during a 24-month observational phase. Descriptive statistical analyses of the safety set as well as of stratified subgroups such as patients with concomitant diabetes mellitus and pretreated patients (e.g., natalizumab) will be conducted. PANGAEA seeks to confirm the current safety profile of fingolimod obtained in phase I-III clinical trials. The study design presented here will additionally provide guidance on the therapeutic use of fingolimod in clinical practice and possibly assists physicians in making evidence-based decisions.

  10. Polarimetric purity and the concept of degree of polarization

    NASA Astrophysics Data System (ADS)

    Gil, José J.; Norrman, Andreas; Friberg, Ari T.; Setälä, Tero

    2018-02-01

    The concept of degree of polarization for electromagnetic waves, in its general three-dimensional version, is revisited in the light of the implications of the recent findings on the structure of polarimetric purity and of the existence of nonregular states of polarization [J. J. Gil et al., Phys Rev. A 95, 053856 (2017), 10.1103/PhysRevA.95.053856]. From the analysis of the characteristic decomposition of a polarization matrix R into an incoherent convex combination of (1) a pure state Rp, (2) a middle state Rm given by an equiprobable mixture of two eigenstates of R, and (3) a fully unpolarized state Ru -3 D, it is found that, in general, Rm exhibits nonzero circular and linear degrees of polarization. Therefore, the degrees of linear and circular polarization of R cannot always be assigned to the single totally polarized component Rp. It is shown that the parameter P3 D proposed formerly by Samson [J. C. Samson, Geophys. J. R. Astron. Soc. 34, 403 (1973), 10.1111/j.1365-246X.1973.tb02404.x] takes into account, in a proper and objective form, all the contributions to polarimetric purity, namely, the contributions to the linear and circular degrees of polarization of R as well as to the stability of the plane containing its polarization ellipse. Consequently, P3 D constitutes a natural representative of the degree of polarimetric purity. Some implications for the common convention for the concept of two-dimensional degree of polarization are also analyzed and discussed.

  11. Macular photostress and visual experience between microscope and intracameral illumination during cataract surgery.

    PubMed

    Seo, Hyejin; Nam, Dong Heun; Lee, Jong Yeon; Park, Su Jin; Kim, Yu Jeong; Kim, Seong-Woo; Chung, Tae-Young; Inoue, Makoto; Kim, Terry

    2018-02-01

    To evaluate macular photostress and visual experience between coaxial microscope illumination versus oblique intracameral illumination during cataract surgery. Gachon University Gil Hospital, Incheon, South Korea. Prospective case series. Consecutive patients who had cataract surgery using microscope illumination and intracameral illumination were included. The patients were asked to complete a questionnaire (seeing strong lights, feeling photophobia, feeling startled (fright) when seeing lights, seeing any colors, seeing any instruments or surgical procedures, and estimating intraoperative visual function) designed to describe their cataract surgery experience. The images projected on the retina of the model eye (rear view) with artificial opaque fragments in the anterior chamber during simulating cataract surgery were compared between the 2 illumination types. Sixty patients completed the questionnaire. Scores for strong lights, photophobia, fright, and color perception were significantly higher with microscope illumination than with intracameral illumination (all P < .001). More patients preferred the intracameral illumination (45 [75.0%]) to the microscope illumination (13 [21.7%]). In the rear-view images created in a model eye, only the bright microscope light in the center was seen without any lens image in the microscope illumination. However, in the intracameral illumination, the less bright light from the light pipe in the periphery and the lens fragments were seen more clearly. In a view of the patients' visual experience, oblique intracameral illumination caused less subjective photostress and was preferred over coaxial microscope illumination. Objective findings from the model-eye experiment correlated to the result of visual experience. Copyright © 2018 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  12. Longevity records and survival estimate of birds in a Guatemala rain forest

    USGS Publications Warehouse

    Robbins, C.S.; Dowell, B.; Hines, J.

    2002-01-01

    Birds were mist-netted for ten consecutive 'winter' seasons at two sites on Cerro San Gil and for three to nine seasons at eight other sites on the mountain. Sixteen nets were used at each site for three days; net locations were the same each year. From 1,255 subsequent-year recaptures we computed annual survival using the program MARK. A low annual survival of 0.26+0.03 for Long-tailed Hermit probably reflects extensive wandering in search of food. The only other residents with low survival rates were Ochre-bellied Flycatcher (0.32) and Olive-backed Euphonia (0.38). Other residents tested ranged from 0.49 for Red-capped Manakin to 0.67 for Stub-tailed Spadebill and are within ranges reported from other tropical sites. Rates for migrants were lower, ranging from 0.33 (Worm-eating Warbler) to 0.45 (Kentucky Warbler). Limiting the analysis to known territorial adults (birds that had already returned from a previous year), raised survival rates for residents an average of 0.05, whereas rates for wintering migratory species remained unchanged. The oldest birds recaptured were all residents: Scalythroated Leaftosser (9 years 9 months), Tawny-winged and Wedge-billed Woodcreepers, Northern Bentbill, Tawny-crowned Greenlet, and White-breasted Woodwren (8 years 9 months each). Ages over three years nine months were recorded for 46 species; for the majority of these, new maximum age records were established. A positive relationship was found between survival rate and maximum age and between sample size and maximum age

  13. PREFACE: XX International School on Nuclear Physics, Neutron Physics and Applications (Varna2013)

    NASA Astrophysics Data System (ADS)

    Stoyanov, Chavdar; Dimitrova, Sevdalina

    2014-09-01

    nuclear waste treatment. Nuclear methods for applications. A special session in honor of the late Mario Stoitsov, was also part of the program. Many colleagues of Mario from all over the world came to Varna to pay tribute to this prominent scientist and loyal friend. Several colleagues contributed to the organization of the School. We would like to thank them and especially the Scientific Secretary of the School Dr Elena Stefanova and the members of the Organizing Committee Dr Dimitar Tarpanov and Peter Zivkov for their cordiality and high level assistance. We are also grateful to Dr Jacek Dobaczewski, who reached out to the collaborators of Mario Stoitsov on behalf of the conference. Sofia, 20 March 2014 Co-chair persons of the Organizing Committee Prof Dr Sc Ch Stoyanov Prof Dr Sc S Dimitrova Details of the committees are available in the PDF.

  14. Association between Minimal Change Esophagitis and Gastric Dysmotility: A Single-Center Electrogastrography and Endoscopy Study in Children.

    PubMed

    Lim, Kyung In; Shim, Sung Bo; Tchah, Hann; Ryoo, Eell

    2018-01-01

    Minimal change esophagitis (MCE) is a reflux disease without mucosal breaks, known to be partially associated with abnormal gastric motor function. Electrogastrography (EGG) is commonly applied to assess gastric motor function in a noninvasive fashion. We aimed to determine the relationship between MCE and gastric myoelectrical activity (GME) recorded on EGG in children. We retrospectively assessed the records of 157 children without underlying disease who underwent both EGG and upper gastrointestinal endoscopy at Gachon University Gil Medical Center between January 2010 and June 2015. The children were stratified according to the appearance of the esophagus (normal vs. MCE). Between-group differences in EGG parameters and their correlation with each MCE finding were statistically analyzed. Only the power ratio, one of the EGG parameters analyzed, differed significantly between the two groups (MCE, 1.68±3.37 vs. normal, 0.76±1.06; p <0.05), whereas the other parameters, such as dominant frequency, dominant power, and the ratio of abnormal rhythm, showed no differences. Among children with MCE, significant correlations were noted between erythema and power ratio ( p <0.05), friability and postprandial dominant frequency ( p <0.05), and edema and/or accentuation of mucosal folds and pre-prandial frequency ( p <0.05). Helicobacter pylori infection correlated with postprandial arrhythmia (MCE, 33.59±15.52 vs. normal, 28.10±17.23; p <0.05). EGG parameters did not differ between children with normal esophagus and those with biopsy-proven chronic esophagitis. In children with MCE, gastric dysmotility may affect the development of MCE, manifesting as EGG abnormalities. H. pylori infection may also affect GME. However, larger prospective investigations are needed to confirm these findings.

  15. Attenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice

    PubMed Central

    Kraft, Andrew W.; Hu, Xiaoyan; Yoon, Hyejin; Yan, Ping; Xiao, Qingli; Wang, Yan; Gil, So Chon; Brown, Jennifer; Wilhelmsson, Ulrika; Restivo, Jessica L.; Cirrito, John R.; Holtzman, David M.; Kim, Jungsu; Pekny, Milos; Lee, Jin-Moo

    2013-01-01

    The accumulation of aggregated amyloid-β (Aβ) in amyloid plaques is a neuropathological hallmark of Alzheimer's disease (AD). Reactive astrocytes are intimately associated with amyloid plaques; however, their role in AD pathogenesis is unclear. We deleted the genes encoding two intermediate filament proteins required for astrocyte activation—glial fibrillary acid protein (Gfap) and vimentin (Vim)—in transgenic mice expressing mutant human amyloid precursor protein and presenilin-1 (APP/PS1). The gene deletions increased amyloid plaque load: APP/PS1 Gfap−/−Vim−/− mice had twice the plaque load of APP/PS1 Gfap+/+Vim+/+ mice at 8 and 12 mo of age. APP expression and soluble and interstitial fluid Aβ levels were unchanged, suggesting that the deletions had no effect on APP processing or Aβ generation. Astrocyte morphology was markedly altered by the deletions: wild-type astrocytes had hypertrophied processes that surrounded and infiltrated plaques, whereas Gfap−/−Vim−/− astrocytes had little process hypertrophy and lacked contact with adjacent plaques. Moreover, Gfap and Vim gene deletion resulted in a marked increase in dystrophic neurites (2- to 3-fold higher than APP/PS1 Gfap+/+Vim+/+ mice), even after normalization for amyloid load. These results suggest that astrocyte activation limits plaque growth and attenuates plaque-related dystrophic neurites. These activities may require intimate contact between astrocyte and plaque.—Kraft, A. W., Hu, X., Yoon, H., Yan, P., Xiao, Q., Wang, Y., Gil, S. C., Brown, J., Wilhelmsson, U., Restivo, J. L., Cirrito, J. R., Holtzman, D. M., Kim, J., Pekny, M., Lee, J.-M. Attenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice. PMID:23038755

  16. Association of cytokines polymorphisms with chronic peridontitis and rheumatoid arthritis in a Mexican population.

    PubMed

    Domínguez-Pérez, Rubén Abraham; Loyola-Rodriguez, Juan Pablo; Abud-Mendoza, Carlos; Alpuche-Solis, Angel Gabriel; Ayala-Herrera, José Luis; Martínez-Martínez, Rita Elizabeth

    2017-05-01

    Historically, it has been shown that rheumatoid arthritis (RA) and periodontitis (PE) share pathophysiological similarities and possibly a genetic background. In order to elucidate the genetic background between both diseases, we evaluated the distributions of five SNPs genotypes and all the possible haplotypes composed in subjects with isolated RA, PE, combined diseases and healthy controls. The study population consisted of 280 Mexican subjects. Genomic DNA was isolated from buccal epithelial cells collected by cheek scrapings and analyzed for the determination of the following SNPs: IL-1α + 4845 (rs17561), IL-1α -889 (rs1800587), IL-1β + 3954 (rs1143634), IL-1β -511(rs16944) and TNF-α -308 (rs1800629). After adjustment for age, sex and smoking status, multiple logistic regression analysis revealed a no significant association in the genotype frequencies of TNF-α -308 and IL-1α + 4845 SNPs. Otherwise a significant association was observed in IL-1β + 3954 and IL-1β -511 (p < 0.05) while IL-1α -889 was of borderline statistical significance (p = 0.054). Also, we found three negative associated haplotypes with PE: IL-1α + 4845 G/IL-1β -511 A, IL-1β + 3954 C/IL-1β -511 A and interestingly IL-1α -889 C/IL-1β -511 A also with a positive association with RA. Some genotypes and haplotypes are associated with the diseases. But it seems that the genetic background of the association between RA and PE needs to be explored deeper.

  17. Risk factors for DSM-5 posttraumatic stress symptoms (PTSS) among Israeli civilians during the 2014 Israel-Hamas war.

    PubMed

    Gil, Sharon; Weinberg, Michael; Shamai, Michal; Ron, Pnina; Harel, Hila; Or-Chen, Keren

    2016-01-01

    In light of current modifications in the 5th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) diagnostic criteria for posttraumatic stress disorder (PTSD), this study aimed to revalidate well-known PTSD risk factors related to terrorism and war in Israel, namely, proximity to the Gaza Strip, dissociative symptoms, acute stress disorder (ASD) symptoms, and social support. One hundred and sixty Israeli civilians were assessed during the 2014 Israel-Hamas war at 2 time points: 1 week after the beginning of the operation (t1) and 1 month after initial evaluation (t2), using the DSM-5 PTSD Symptom Levels Scale (PSLS; Gil, Weinberg, Or-Chen, & Harel, 2015). A paired t test analysis showed significant reduction in the respondents' posttraumatic stress symptoms (PTSS) 1 month after the initial assessment point. A structural equation model (SEM) showed that higher ASD symptoms at t1 and higher dissociative symptoms at t2 increased the risk for PTSS at t2. Conversely, higher peritraumatic dissociation at t1 decreased the risk for PTSS at t2. Proximity to the Gaza Strip, and social support, failed to demonstrate significant association with PTSS at t2. DSM-5 PTSS 1 month after prolonged traumatic exposure are strongly associated with high ASD symptoms at 1 week as a risk factor; high levels of peritraumatic dissociation at 1 week as a protective factor; and high levels of dissociative symptoms at 1 month as a risk factor. Theoretically and clinically the findings of the study further suggest that ongoing massive terrorism and war cannot be viewed or treated as identical to other traumas. (c) 2016 APA, all rights reserved).

  18. Interaction of colloidal nanoparticles with cells (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Parak, Wolfgang J.

    2017-02-01

    What happens to inorganic nanoparticles (NPs), such as plasmonic gold or silver, superparamagnetic iron oxide, or fluorescent quantum dot NPs, after they have been administrated to an animal or a human being? The review discusses the integrity, biodistribution, and fate of NPs after in vivo administration. First the hybrid nature of the NPs is described, by conceptually dividing them into the inorganic NP core, an engineered surface coating around the core which comprises the ligand shell and optionally also bioconjugation, and into the corona of adsorbed biological molecules. It is shown that in vivo all of these three compounds may degrade individually and that each of them can drastically modify the life-cycle and biodistribution of the whole hetero-structure. The NPs thus may be disintegrated into different parts, of which biodistribution and fate would need to be analyzed individually. Multiple labelling and quantification strategies for such purpose will be discussed. All reviewed data indicate that in vivo NPs no longer should be considered as homogeneous entity, but should be seen as inorganic/organic/biological nano-hybrids with complex and intricately linked degradation pathways. References: M. Chanana, P. Rivera Gil, M. A. Correa-Duarte, L. M. Liz-Marzán. W. J. Parak, "Physicochemical Properties of Protein-Coated Gold Nanoparticles in Biological Fluids and Cells before and after Proteolytic Digestion", Angewandte Chemie International Edition 52, 4179-4183 (2013). W. G. Kreyling, A. M. Abdelmonem, Z. Ali, F. Alves, M. Geiser, N. Haberl, R. Hartmann, S. Hirn, K. Kantner, D. Jimenez de Aberasturi, G. Khadem-Saba, J.-M. Montenegro, J. Rejman, T. Rojo, I. Ruiz de Larramendi, R. Ufartes, A. Wenk, W. J. Parak, "In vivo integrity of polymer-coated gold nanoparticles", Nature Nanotechnology 10, 619-623 (2015).J. Clerk Maxwell, A Treatise on Electricity and Magnetism, 3rd ed., vol. 2. Oxford: Clarendon, 1892, pp.68-73.

  19. A Single Oxidosqualene Cyclase Produces the Seco-Triterpenoid α-Onocerin1[OPEN

    PubMed Central

    Almeida, Aldo; Khakimov, Bekzod; Bassard, Jean-Etienne; Appendino, Giovanni

    2018-01-01

    8,14-seco-Triterpenoids are characterized by their unusual open C-ring. Their distribution in nature is rare and scattered in taxonomically unrelated plants. The 8,14-seco-triterpenoid α-onocerin is only known from the evolutionarily distant clubmoss genus Lycopodium and the leguminous genus Ononis, which makes the biosynthesis of this seco-triterpenoid intriguing from an evolutionary standpoint. In our experiments with Ononis spinosa, α-onocerin was detected only in the roots. Through transcriptome analysis of the roots, an oxidosqualene cyclase, OsONS1, was identified that produces α-onocerin from squalene-2,3;22,23-dioxide when transiently expressed in Nicotiana bethamiana. In contrast, in Lycopodium clavatum, two sequential cyclases, LcLCC and LcLCD, are required to produce α-onocerin in the N. benthamiana transient expression system. Expression of OsONS1 in the lanosterol synthase knockout yeast strain GIL77, which accumulates squalene-2,3;22,23-dioxide, verified the α-onocerin production. A phylogenetic analysis predicts that OsONS1 branches off from specific lupeol synthases and does not group with the known L. clavatum α-onocerin cyclases. Both the biochemical and phylogenetic analyses of OsONS1 suggest convergent evolution of the α-onocerin pathways. When OsONS1 was coexpressed in N. benthamiana leaves with either of the two O. spinosa squalene epoxidases, OsSQE1 or OsSQE2, α-onocerin production was boosted, most likely because the epoxidases produce higher amounts of squalene-2,3;22,23-dioxide. Fluorescence lifetime imaging microscopy analysis demonstrated specific protein-protein interactions between OsONS1 and both O. spinosa squalene epoxidases. Coexpression of OsONS1 with the two OsSQEs suggests that OsSQE2 is the preferred partner of OsONS1 in planta. Our results provide an example of the convergent evolution of plant specialized metabolism. PMID:29203557

  20. Lagoon-sea exchanges, nutrient dynamics and water quality management of the Ria Formosa (Portugal)

    NASA Astrophysics Data System (ADS)

    Newton, Alice; Mudge, Stephen M.

    2005-02-01

    Historical data from the Ria Formosa lagoon are classified according to the EEA 2001 guidelines to provide a frame of reference to evaluate the effect of management during the implementation of the environmental legislative Directives. Water samples from the Ria Formosa lagoon were significantly enriched in nitrogen (NH 4+ NO 2- and NO 3-) with respect to the adjacent coastal waters indicating that inputs from sewage, agricultural runoff and benthic fluxes were not fully assimilated within the lagoon. Tidal flushing was insufficient in the inner areas of the lagoon to remove or effectively dilute these inputs. Enrichment was most severe close to the urban centres of Faro and Olhão, as well as in the Gilão Estuary and the shallow extremities. Dissolved oxygen undersaturation (mean 75% during daylight hours) was associated with the area close to the sewage outlets of Faro. In the shallow west end of the lagoon during summer, dissolved oxygen supersaturation reached 140% during the day but fell to 50% at night. Classification using the EEA (2001) guidelines suggests the system is "poor" or "bad" with respect to phosphate concentrations for the majority of the year and "poor" in nitrogen contamination during the autumn rainy period. Due to the high overall nitrogen load in the lagoon, there is a net export to the coastal waters, especially during November and December, and phosphate only becomes limiting briefly during the spring bloom (April). Therefore, substantial phytoplankton populations may be supported year-round in the lagoon. The consequences of water quality deterioration in the Ria Formosa would negatively affect the lagoon as a regional resource, important for its ecological, economic and recreational value. The industries most affected would be tourism, fisheries and aquaculture. Management options include Urban Waste Water Treatment, dredging, artificial inlets, limits on urban development and changes in agricultural practices.

  1. Project SunSHINE: A Student Based Solar Research Program

    NASA Astrophysics Data System (ADS)

    Donahue, R.

    2000-12-01

    Eastchester Middle School (NY) is currently conducting an ongoing, interdisciplinary solar research program entitled Project SunSHINE, for Students Help Investigate Nature in Eastchester. Students are to determine how ultraviolet and visible light levels vary throughout the year at the school's geographic location, and to ascertain if any measured variations correlate to daily weather conditions or sunspot activity. The educational goal is to provide students the opportunity to conduct original and meaningful scientific research, while learning to work collaboratively with peers and teachers in accordance with national mathematics, science and technology standards. Project SunSHINE requires the student researchers to employ a number of technologies to collect and analyze data, including light sensors, astronomical imaging software, an onsite AirWatch Weather Station, Internet access to retrieve daily solar images from the National Solar Observatory's Kitt Peak Vacuum Telescope, and two wide field telescopes for live sunspot observations. The program has been integrated into the science, mathematics, health and computer technology classes. Solar and weather datasets are emailed weekly to physicist Dr. Gil Yanow of the Jet Propulsion Laboratory for inclusion in his global study of light levels. Dr. Yanow credited the Project SunSHINE student researchers last year for the discovery of an inverse relationship between relative humidity and ultraviolet light levels. The Journal News Golden Apple Awards named Project SunSHINE the 1999 New York Wired Applied Technology Award winner. This honor recognizes the year's outstanding educational technology program at both the elementary and secondary level, and included a grant of \\$20,000 to the research program. Teacher training and image processing software for Project SunSHINE has been supplied by The Use of Astronomy in Research Based Science Education (RBSE), a Teacher Enhancement Program funded by the National Science

  2. [Biological contamination in office buildings related to ventilation/air conditioning system].

    PubMed

    Bródka, Karolina; Sowiak, Małgorzata; Kozajda, Anna; Cyprowski, Marcin; Irena, Szadkowska-Stańczyk

    2012-01-01

    Indoor air is contaminated with microorganisms coming from both the atmospheric air and sources present in premises. The aim of this study was to analyze the concentrations of biological agents in office buildings, dependending on ventilation/air conditioning system and season. The study covered office buildings (different in the system of ventila-tion/air conditioning). Air samples for assessing the levels of inhalable dust, endotoxins and (1-->3)-beta-D-glucans, were taken at the selected stationary points of each building during summer and winter. The air was sampled for 6 h, using portable sets consisting of the GilAir 5 pump and the head filled with a filter of fiber glass. The samples for the presence of airborne bacteria and fungi were collected twice during the day using the impaction method. Average concentrations of inhalable dust, bacteria, fungi, endotoxins and (1-->3)-beta-D-glucans in office premises were 0.09 mg/m3, 6.00 x 10(2) cfu/m3, 4.59 x 10(1) cfu/m3, 0.42 ng/m3 and 3.91 ng/m3, respectively. Higher concentrations of the investigated agents were found in summer. In premises with air conditioning concentrations of airborne fungi, (1-->3)-beta-D-glucans and inhalable dust were significantly lower in winter. In summer the trend was reverse except for (1-->3)-beta-D-glucans. Concentrations of biological agents were affected by the season and the presence of air conditioning. Concentrations of inhalable dust, bacteria, fungi, endotoxins and (1-->3)-beta-D-glucans, observed inside the office buildings, were significantly higher in summer than in winter. The presence of the air conditioning system modified in various ways the levels of biological agents. Its influence was greater on the concentration of fungi and (1-->3)-beta-D-glucans than on that of bacteria and endotoxins.

  3. Species and Scale Dependence of Bacterial Motion Dynamics

    NASA Astrophysics Data System (ADS)

    Sund, N. L.; Yang, X.; Parashar, R.; Plymale, A.; Hu, D.; Kelly, R.; Scheibe, T. D.

    2017-12-01

    Many metal reducing bacteria are motile with their motion characteristics described by run-and-tumble behavior exhibiting series of flights (jumps) and waiting (residence) time spanning a wide range of values. Accurate models of motility allow for improved design and evaluation of in-situ bioremediation in the subsurface. While many bioremediation models neglect the motion of the bacteria, others treat motility using an advection dispersion equation, which assumes that the motion of the bacteria is Brownian.The assumption of Brownian motion to describe motility has enormous implications on predictive capabilities of bioremediation models, yet experimental evidence of this assumption is mixed [1][2][3]. We hypothesize that this is due to the species and scale dependence of the motion dynamics. We test our hypothesis by analyzing videos of motile bacteria of five different species in open domains. Trajectories of individual cells ranging from several seconds to few minutes in duration are extracted in neutral conditions (in the absence of any chemical gradient). The density of the bacteria is kept low so that the interaction between the bacteria is minimal. Preliminary results show a transition from Fickian (Brownian) to non-Fickian behavior for one species of bacteria (Pelosinus) and persistent Fickian behavior of another species (Geobacter).Figure: Video frames of motile bacteria with the last 10 seconds of their trajectories drawn in red. (left) Pelosinus and (right) Geobacter.[1] Ariel, Gil, et al. "Swarming bacteria migrate by Lévy Walk." Nature Communications 6 (2015).[2] Saragosti, Jonathan, Pascal Silberzan, and Axel Buguin. "Modeling E. coli tumbles by rotational diffusion. Implications for chemotaxis." PloS one 7.4 (2012): e35412.[3] Wu, Mingming, et al. "Collective bacterial dynamics revealed using a three-dimensional population-scale defocused particle tracking technique." Applied and Environmental Microbiology 72.7 (2006): 4987-4994.

  4. Clinical and Demographic Profile of Patients Receiving Fingolimod in Clinical Practice in Germany and the Benefit-Risk Profile of Fingolimod After 1 Year of Treatment: Initial Results From the Observational, Noninterventional Study PANGAEA.

    PubMed

    Ziemssen, Tjalf; Lang, Michael; Tackenberg, Björn; Schmidt, Stephan; Albrecht, Holger; Klotz, Luisa; Haas, Judith; Lassek, Christoph; Medin, Jennie; Cornelissen, Christian

    2018-01-01

    The population with multiple sclerosis receiving treatment in clinical practice differs from that in randomized controlled trials (RCTs). An assessment of the real-world benefit-risk profile of therapies is needed. This analysis used data from the large, noninterventional, observational German study Post-Authorization Non-interventional German sAfety study of GilEnyA (PANGAEA) to assess prospectively baseline characteristics and outcomes after 12 months (± 90 days) of fingolimod treatment. Patients were divided into 2 cohorts: fingolimod starter [first received fingolimod in PANGAEA (n = 3315)] and previous study [received fingolimod before enrollment in PANGAEA in RCTs (n = 875), some of whom also had baseline data at entry into RCTs (n = 505)]. At PANGAEA baseline, patients in the fingolimod starter versus the previous study cohort had a higher annualized relapse rate [ARR (95% confidence interval): 1.79 (1.75-1.83) vs 1.32 (1.25-1.40)] and Expanded Disability Status Scale score [3.11 (3.04-3.17) vs 2.55 (2.44-2.66)]. A greater proportion in the fingolimod starter versus previous study cohort had diabetes (2.0% vs 0.7%). After 12 months of fingolimod, ARRs were lower than in the 12 months before PANGAEA enrollment in the fingolimod starter [0.386 (0.360-0.414)] and previous study [0.276 (0.238-0.320)] cohorts. Expanded Disability Status Scale scores were stable versus baseline. Adverse events were experienced by similar proportions in both cohorts during fingolimod treatment. Relevant differences exist in disease activity and comorbidities between patients receiving fingolimod in clinical practice versus RCTs. Irrespective of baseline differences indicating a higher proportion at an advanced stage of multiple sclerosis in the real world versus RCTs, fingolimod remains effective, with a manageable safety profile.

  5. Overview and Brief History of the Boron Isotope Proxy for Past Seawater pH

    NASA Astrophysics Data System (ADS)

    Hoenisch, B.; Hemming, G.

    2007-05-01

    In 1992 Hemming and Hanson (GCA, vol. 56, p. 537-543) showed that a variety of modern marine carbonates revealed a boron isotopic composition close to the isotopic composition of dissolved borate at modern seawater pH, suggesting this was the boron species preferentially adsorbed and incorporated into marine carbonates. With a constant offset between the trigonal and tetrahedrally coordinated boron species and a pH-dependent variation in their fractions, it appeared that this system would be sensitive to pH changes in the natural range of seawater. Accordingly, it was suggested that the boron isotope composition of marine carbonates is a proxy for past seawater pH. Subsequent culture studies with living planktic foraminifers and corals, as well as synthetic precipitation experiments confirmed that the boron isotopic composition follows the isotopic composition of borate across a wide range of seawater pH. In order to use the proxy with confidence, however, all other controls apart from pH need to be thoroughly understood. Recent laboratory and sediment experiments have demonstrated that vital effects and partial shell dissolution have the potential to modify the primary seawater pH signal recorded in the boron isotopic composition of planktic foraminifers. However it has also been shown that careful sample selection allows for avoiding these potential complications. A record of reconstructed surface seawater pH and estimated aqueous PCO2 shows a remarkable match between boron isotope based atmospheric pCO2 estimates and the Vostok ice core CO2 record. This convincingly demonstrates that boron isotopes in planktic foraminifers allow quantitative estimates of atmospheric pCO2 in the past, and confirms that glacial surface ocean pH was ~0.2 units higher compared to interglacial periods. We are going to review and discuss the achievements generated in Gil Hanson's lab over the past 15 years in the light of recent empirical measurements of the boron isotope

  6. Sedimentologic Expression of the Cretaceous OAEs in a Tropical Epicontinental Sea

    NASA Astrophysics Data System (ADS)

    Silva-Tamayo, J. C.; Eisenhauer, A.

    2015-12-01

    The acidification and deoxygention of modern oceans are major environmental concerns to the international community. The effects of ocean acidification and deoxigention in the biogeochemical cycles of modern tropical oceans are poorly constrained mainly due to the lack of empirical and quantitative data. The Cretaceous World witnessed several period of potential ocean acidification and deoxygenation, which resulted from the rapid additions of volcanic derived CO2 to the atmosphere. The effects of ocean acidification and deoxygenation on the Cretaceous biogeochemical cycles are evidenced mainly by major global C-isotope anomalies. These anomalies parallel the occurrence of organic rich black shales as well as major decreases in the deposition of shallow marine carbonates worldwide. Here we use detailed C- and Sr- chemostratigraphy as well as published bioestratigraphic information and volcanic zircon U-Pb ages to precisely constrain the geochemical and sedimentologic expression of the Cretaceous OAES along a tropical epicontinental sea, the La Luna Sea. Our multi-pronged approach allows identifying the occurrence of several of the Cretaceous Oceanic Anoxic Events (OAEs) in carbonate units paleogeographically located along the northern most part of the La Luna Sea, i.e. Weissert-OAE-(Palanz and Rosablanca Formations), Faraoni-(Rosablanca Formation), AOE1a-(Paja and Fomeque Formations, Cogollo Group), OAE1c-(Cogollo Group), OAE2-(Cogollo Group), OAE3-(La Luna Formation). These events are preserved in highly euxinic - organic rich "black shales" successions deposited along the deepest part of the seaway at the Middle Magdalena Valley and Cundinamarca Basin; Weiser-OAE-(Lutitas de Macanal Formation), OAE1a-(Paja Formation, Fomeque Formation), OAE1C-(San Gil Formation). Regional changes in depositional settings and sedimentary facies preserving the different Cretaceous OAEs were likely the result of the combined action of regional changes in paleogeography and tectonic

  7. Towards a complete Fermi surface in underdoped high Tc superconductors

    NASA Astrophysics Data System (ADS)

    Harrison, Neil

    The discovery of magnetic quantum oscillations in underdoped high Tc superconductors raised many questions, and initiated a quest to understand the origin of the Fermi surface the like of which had not been seen since the very first discovery of quantum oscillations in elemental bismuth. While studies of the Fermi surface of materials are today mostly assisted by computer codes for calculating the electronic band structure, this was not the case in the underdoped high Tc materials. The Fermi surface was shown to reconstructed into small pockets, yet there was no hint of a viable order parameter. Crucial clues to understanding the origin of the Fermi surface were provided by the small value of the observed Fermi surface cross-section, the negative Hall coefficient and the small electronic heat capacity at high magnetic fields. We also know that the magnetic fields were likely to be too weak to destroy the pseudogap and that vortex pinning effects could be seen to persist to high magnetic fields at low temperatures. I will show that the Fermi surface that appears to fit best with the experimental observations is a small electron pocket formed by connecting the nodal `Fermi arcs' seen in photoemission experiments, corresponding to a density-wave state with two different orthogonal ordering vectors. The existence of such order has subsequently been detected by x-ray scattering experiments, thereby strengthening the case for charge ordering being responsible for reconstructing the Fermi surface. I will discuss new efforts to understand the relationship between the charge ordering and the pseudogap state, discussing the fate of the quasiparticles in the antinodal region and the dimensionality of the Fermi surface. The author acknowledges contributions from Suchitra Sebastian, Brad Ramshaw, Mun Chan, Yu-Te Hsu, Mate Hartstein, Gil Lonzarich, Beng Tan, Arkady Shekhter, Fedor Balakirev, Ross McDonald, Jon Betts, Moaz Altarawneh, Zengwei Zhu, Chuck Mielke, James Day, Doug

  8. PREFACE: 10th Summer School on Theoretical Physics 'Symmetry and Structural Properties of Condensed Matter'

    NASA Astrophysics Data System (ADS)

    Lulek, Tadeusz; Wal, Andrzej; Lulek, Barbara

    2010-03-01

    also for several valuable discussion. We would like to express our thanks to all those who prepared manuscripts, to all referees who spent their time to significantly improve our elaborations, and thus the quality of this volume, to all members of our International Advisory Committee and to chairmen for their polite and efficient leading of sessions. It is our pleasure to express special gratitude to The Nicolas C Metropolis Mathematics Foundation (Los Alamos, USA) for substantial financial support of our three last SSPCM schools. Indeed, it provided an essential basis for performing these meetings. We direct this gratitude to Professor James D Louck, the President of this Foundation. Also, we were happy to hear from Professor Louck that this series of schools has had an important influence on his activities on application of unitary groups in physics. It has resulted in a new monograph: James D Louck, 'Unitary Symmetry and Combinatorics', World Scientific, New Jersey 2008, which was presented at our jubilee meeting. Tadeusz Lulek, Andrzej Wal and Barbara Lulek

  9. Highlights of Astronomy

    NASA Astrophysics Data System (ADS)

    van der Hucht, Karel

    2008-02-01

    Preface Karel A. van der Hucht; Part I. Invited Discourses: Part II. Joint Discussions: 1. Particle acceleration - from Solar System to AGN Marian Karlicky and John C. Brown; 2. Pulsar emission and related phenomena Werner Becker, Janusz A. Gil and Bronislaw Rudak; 3. Solar activity regions and magnetic structure Debi Prasad Choudhary and Michal Sobotka; 4. The ultraviolet universe: Stars from birth to death Ana I. Gomez de Castro and Martin A. Barstow; 5. Calibrating the top of the stellar M-L relationship Claus Leitherer, Anthony F. J. Moat and Joachim Puls; 6. Neutron stars and black holes in star clusters Frederic A. Rasio; 7. The Universe at z > 6 Daniel Schaerer and Andrea Ferrara; 8. Solar and stellar activity cycles Klaus G. Strassmeier and Alexander Kosovichev; 9. Supernovae: One millennium after SN 1006 P. Frank Winkler, Wolfgang Hillebrandt and Brian P. Schmidt; 10. Progress in planetary exploration missions Guy J. Consolmagno; 11. Pre-solar grains as astrophysical tools Anja C. Andersen and John C. Lattanzio; 12. Long wavelength astrophysics T. Joseph W. Lazio and Namir E. Kassim; 13. Exploiting large surveys for galactic astronomy Christopher J. Corbally, Coryn A. L. Bailer-Jones, Sunetra Giridhar and Thomas H. Lloyd Evans; 14. Modeling dense stellar systems Alison I. Sills, Ladislav Subr and Simon F. Portegies Zwart; 15. New cosmology results from the Spitzer Space Telescope George Helou and David T. Frayer; 16. Nomenclature, precession and new models in fundamental astronomy Nicole Capitaine, Jan Vondrak & James L. Hilton; 17. Highlights of recent progress in seismology of the Sun and Sun-like stars John W. Leibacher and Michael J. Thompson; Part III. Special Sessions: SpS 1. Large astronomical facilities of the next decade Gerard F. Gilmore and Richard T. Schilizzi; SpS 2. Innovation in teaching and learning astronomy methods Rosa M. Ros and Jay M. Pasachoff; SpS 3. The Virtual Observatory in action: New science, new technology and next

  10. Highlights of Astronomy, Volume 14

    NASA Astrophysics Data System (ADS)

    van der Hucht, Karel

    2007-08-01

    Preface Karel A. van der Hucht; Part I. Invited Discourses: Part II. Joint Discussions: 1. Particle acceleration - from Solar System to AGN Marian Karlicky and John C. Brown; 2. Pulsar emission and related phenomena Werner Becker, Janusz A. Gil and Bronislaw Rudak; 3. Solar activity regions and magnetic structure Debi Prasad Choudhary and Michal Sobotka; 4. The ultraviolet universe: Stars from birth to death Ana I. Gomez de Castro and Martin A. Barstow; 5. Calibrating the top of the stellar M-L relationship Claus Leitherer, Anthony F. J. Moat and Joachim Puls; 6. Neutron stars and black holes in star clusters Frederic A. Rasio; 7. The Universe at z > 6 Daniel Schaerer and Andrea Ferrara; 8. Solar and stellar activity cycles Klaus G. Strassmeier and Alexander Kosovichev; 9. Supernovae: One millennium after SN 1006 P. Frank Winkler, Wolfgang Hillebrandt and Brian P. Schmidt; 10. Progress in planetary exploration missions Guy J. Consolmagno; 11. Pre-solar grains as astrophysical tools Anja C. Andersen and John C. Lattanzio; 12. Long wavelength astrophysics T. Joseph W. Lazio and Namir E. Kassim; 13. Exploiting large surveys for galactic astronomy Christopher J. Corbally, Coryn A. L. Bailer-Jones, Sunetra Giridhar and Thomas H. Lloyd Evans; 14. Modeling dense stellar systems Alison I. Sills, Ladislav Subr and Simon F. Portegies Zwart; 15. New cosmology results from the Spitzer Space Telescope George Helou and David T. Frayer; 16. Nomenclature, precession and new models in fundamental astronomy Nicole Capitaine, Jan Vondrak & James L. Hilton; 17. Highlights of recent progress in seismology of the Sun and Sun-like stars John W. Leibacher and Michael J. Thompson; Part III. Special Sessions: SpS 1. Large astronomical facilities of the next decade Gerard F. Gilmore and Richard T. Schilizzi; SpS 2. Innovation in teaching and learning astronomy methods Rosa M. Ros and Jay M. Pasachoff; SpS 3. The Virtual Observatory in action: New science, new technology and next

  11. Otto LaPorte Lecture: Ultimate Rayleigh-Bénard and Taylor-Couette turbulence

    NASA Astrophysics Data System (ADS)

    Lohse, Detlef

    2017-11-01

    Chao Sun, Roberto Verzicco, Siegfried Grossmann, Richard Stevens, Erwin van der Poel, Rodolfo Ostilla-Monico, Xiaojue Zhu, Dennis van Gils, Sander Huisman, Ruben Verschoof, and Gert-Wim Bruggert.

  12. Study design of PANGAEA 2.0, a non-interventional study on RRMS patients to be switched to fingolimod.

    PubMed

    Ziemssen, Tjalf; Kern, Raimar; Cornelissen, Christian

    2016-08-08

    The therapeutic options for patients with Multiple Sclerosis (MS) have steadily increased due to the approval of new substances that now supplement traditional first-line agents, demanding a paradigm shift in the assessment of disease activity and treatment response in clinical routine. Here, we report the study design of PANGAEA 2.0 (Post-Authorization Non-interventional GermAn treatment benefit study of GilEnyA in MS patients), a non-interventional study in patients with relapsing-remitting MS (RRMS) identify patients with disease activity and monitor their disease course after treatment switch to fingolimod (Gilenya®), an oral medication approved for patients with highly active RRMS. In the first phase of the PANGAEA 2.0 study the disease activity status of patients receiving a disease-modifying therapy (DMT) is evaluated in order to identify patients at risk of disease progression. This evaluation is based on outcome parameters for both clinical disease activity and magnetic resonance imaging (MRI), and subclinical measures, describing disease activity from the physician's and the patient's perspective. In the second phase of the study, 1500 RRMS patients identified as being non-responders and switched to fingolimod (oral, 0.5 mg/daily) are followed-up for 3 years. Data on relapse activity, disability progression, MRI lesions, and brain volume loss will be assessed in accordance to 'no evidence of disease activity-4' (NEDA-4). The modified Rio score, currently validated for the evaluation of treatment response to interferons, will be used to evaluate the treatment response to fingolimod. The MS management software MSDS3D will guide physicians through the complex processes of diagnosis and treatment. A sub-study further analyzes the benefits of a standardized quantitative evaluation of routine MRI scans by a central reading facility. PANGAEA 2.0 is being conducted between June 2015 and December 2019 in 350 neurological practices and centers in Germany

  13. Global Implications of late Pleistocene Megafaunal Extinctions in the Holarctic

    NASA Astrophysics Data System (ADS)

    Cooper, Alan; Turney, Chris

    2017-04-01

    ández, P.M., Gasco, A., Duran, V., Seymour, K.L., Otaola, C., Gil, A., Paunero, R., Prevosti, F.J., Bradshaw, C.J.A., Wheeler, J.C., Borrero, L., Austin, J.J., Cooper, A., 2016. Synergistic roles of climate warming and human occupation in Patagonian megafaunal extinctions during the Last Deglaciation. Science Advances 2, doi: 10.1126/sciadv.1501682.

  14. Clinical-Functional Vulnerability Index-20 (IVCF-20): rapid recognition of frail older adults.

    PubMed

    Moraes, Edgar Nunes de; Carmo, Juliana Alves do; Moraes, Flávia Lanna de; Azevedo, Raquel Souza; Machado, Carla Jorge; Montilla, Dalia Elena Romero

    2016-12-22

    , in addition to the results indicating a high degree of validity and reliability. Thus, the Clinical-Functional Vulnerability Index-20 proves to be viable as a triage instrument in the primary health care that identifies frail older adults (older adults at risk of weakening and frail older adults). Avaliar a adequação do Índice de Vulnerabilidade Clínico-Funcional-20 , instrumento de triagem rápida de vulnerabilidade em idosos brasileiros, para utilização pela atenção básica. O estudo incluiu amostra de conveniência de 397 pacientes com idade maior ou igual a 60 anos atendidos em um Centro de Referência para o Idoso e de 52 idosos da mesma idade atendidos na comunidade. Os resultados do questionário, constituído por 20 perguntas, foram comparados com aqueles da Avaliação Geriátrica Ampla, considerada referência para identificação do idoso frágil. Foi avaliada a correlação de Spearman do Índice de Vulnerabilidade Clínico-Funcional-20 com a Avaliação Geriátrica Ampla; a validade foi verificada pela área sob a curva ROC; a confiabilidade foi estimada pelo percentual de concordância entre avaliadores e coeficiente kappa, ambos com ponderação quadrática. Obteve-se ponto de corte com base no critério de maior acurácia. O alfa de Cronbach, medida de consistência interna, foi calculado. O coeficiente de correlação de Spearman foi elevado e positivo em ambos os grupos (0,792 para idosos atendidos no Centro de Referência para o Idoso e 0,305 para idosos da comunidade [p < 0,001]). A área sob a curva ROC para idosos atendidos no Centro de Referência para o Idoso foi substancial (0,903). O ponto de corte obtido foi seis e idosos com pontuação no Índice de Vulnerabilidade Clínico-Funcional-20 acima desse valor tinham forte possibilidade de serem frágeis. Para idosos da comunidade, a concordância ponderada quadrática entre avaliadores foi 99,5% e o coeficiente kappa ponderado quadrático global, 0,94. O alfa de Cronbach foi elevado

  15. From surfaces to magnetic properties: special section dedicated to Juan Rojo

    NASA Astrophysics Data System (ADS)

    Mascaraque, A.; Rodríguez de la Fuente, O.; González-Barrio, Miguel A.

    2013-12-01

    Surface physics and magnetism, in particular the connection between surface defects, reduced dimensionality or size, crystal structure, electronic density of states and the mechanical and magnetic properties of solids, were always at the core of Juan Rojo's scientific interest and output. Both fields seem to meet at the nanoscale, a privileged playing field which is ideal for testing theoretical concepts, exploring new physics or probing a wealth of new, stunning and unheard-of applications. Upon reducing size or dimensionality, either in bulk systems or in thin films, surfaces and surface effects are telling. Thus, for instance, an ultra-thin coating can make nanoparticles of non-magnetic materials exhibit magnetic behaviour; or atomic steps can modify the local mechanical properties of a metallic single crystal. In this special section there are eight invited papers by disciples and close collaborators of Juan Rojo, that cover an ample spectrum of the above mentioned topics. The first paper, by Palacio et al, investigates the temperature and oxygen partial pressure conditions for FeO mono- and bi-layer growth on Ru(0001). The following paper, by Cortés-Gil et al, reports on the dramatic change in the electric resistivity of the manganite perovskite (La0.5Ca0.5)z MnO3 as a function of Ca content, an effect related to the removal of a charge-ordered state and a magnetic transition. Baeza et al study biomaterials for bone cancer treatment and skeletal reinforcing, as well as targeted magnetic nanoparticles used for intracell hyperthermia in cancer therapies. In the following paper, Marcano et al, assisted by a multi-technique approach, revisit the extraordinarily rich magnetic phase diagram of the Kondo system CeNi1- x Cux down to 100 mK temperatures. The magnetic field dependence of the martensitic transition temperature of the meta-magnetic shape memory alloy Ni50Mn34.5In15.5 in a crystalline and amorphous phase, in fields up to 13 T, is the subject of the paper

  16. PREFACE: Joint European Magnetic Symposia - JEMS 2010

    NASA Astrophysics Data System (ADS)

    Spałek, Jozef

    2011-07-01

    łekChairman of JEMS 2010 Symposia 1. Plenary, Semi-plenary, Tutorials 2. Magnetization Processes Spin Excitations and Ultrafast DynamicsCoordinator: Andrzej Maziewski (Bialystok) 3. Hard Magnetic Materials and MagnetocaloricsCoordinator: Henryk Figiel (Kraków) 4. Magnetic HydridesCoordinators: Ladislav Havela (Praha), Zbigniew Tarnawski (Kraków) 5. Interface of Magnetic Thin FilmsCoordinators: Jürgen Fassbender (Dresden), N-T H Kim-Ngan (Kraków) 6. Magnonic CrystalsCoordinators: Bahram Djafari-Rouhani (Lille), Henryk Puszkarski (Poznan) 7. Magnetism of Metals, Alloys, and IntermetallicsCoordinator: Andrzej Szytula (Kraków) 8. Molecular MagnetismCoordinators: Stephen Blundell (Oxford), Maria Balanda (Kraków) 9. Magnetooptics of NanomagnetsCoordinators: Kamil Postava (Ostrava), Marek Kisielewski (Bialystok) 10. NanomagnetismCoordinators: Marek Przybylski (Halle), Jürgen Kirschner (Halle) 11. Other topics - Biomagnetism, Domain Walls, InstrumentationCoordinator: Henryk Figiel (Kraków) 12. Magnetic Perovskites and MultiferroicsCoordinator: Henryk Szymczak (Warszawa) 13. Magnetic Semiconductors and InsulatorsCoordinators: Klaus Baerner (Göttingen), Tadeusz Gron (Katowice) 14. Magnetic Shape Memory Effects and Related PhenomenaCoordinators: Oliver Gutfleisch (Dresden), Sebastian Fähler (Dresden) 15. Soft Magnetic MaterialsCoordinators: Julian González (San Sebastian), Krzysztof Kulakowski (Kraków) 16. SpintronicsCoordinator: Maciej Sawicki (Warszawa) 17. Strongly Correlated Electron Systems, Magnetism and SuperconductivityCoordinator: Andrzej Slebarski (Katowice) The next Joint European Magnetic Symposia, JEMS 2012, will be held in Parma, Italy, 9-14 September 2012.www.jems2012.itCo-Chairs:Franca Albertini, Institute of Materials for Electronics and Magnetism (IMEM), CNR, ParmaRoberto De Renzi, Department of Physics, University of Parma

  17. A high resolution method for soil moisture mapping at large spatial and temporal scales

    NASA Astrophysics Data System (ADS)

    moreno, D.; Sayde, C.; Ochsner, T. E.; Sorin, C.; Selker, J. S.

    2013-12-01

    in this material are those of the authors and do not necessarily reflect the views of NASA or the National Science Foundation.. Sayde, C., C. Gregory, M. Gil-Rodriguez, N. Tufillaro, S. Tyler, N. van de Giesen, M. English, R. Cuenca, and J.S. Selker (2010), Feasibility of soil moisture monitoring with heated fiber optics, Water Resour. Res., 46, W06201, doi:10.1029/2009WR007846.

  18. PREFACE: 3rd International Symposium on Functional Materials 2009 (ISFM 2009) 3rd International Symposium on Functional Materials 2009 (ISFM 2009)

    NASA Astrophysics Data System (ADS)

    Kiwon, Kim; Li, Lu; Taehyun, Nam; Jouhyeon, Ahn

    2010-05-01

    The 3rd International Symposium on Functional Materials 2009 (ISFM 2009) and its preconference, Advances in Functional Materials 2009 (AFM 2009), were successfully held in the Republic of Korea from 15-18 June 2009 and in the People's Republic of China from 8-12 June 2009, respectively. The two conferences attracted over 300 oral and poster presentations from over 12 countries including Australia, Canada, China, Germany, Japan, India, Israel, Korea, The Netherlands, Thailand, the UK and the USA. In the two conferences, eight keynote lectures were delivered by S Miyazaki, S A Akbar, D J Singh, C Suryanarayana, M~Greenblatt, H Zhang, T Sato and J Ding. This topical issue of Physica Scripta contains papers presented at the ISFM 2009 and AFM 2009. Keyan Li from Dalian University, People's Republic of China, presents some empirical formulae to estimate the elastic moduli of rocksalt-, zincblende- and chalcopyrite-structured crystals, on the basis of electronegativities of bonded atoms in the crystallographic frame. Min-Jung Kim from Hanyang University, Korea, reports on the preparation and characterization of carboxyl functionalization of magnetite nanoparticles for oligonucleotide immobilization. F Yan from the National University of Singapore studies the fabrication of Bi(Fe0.5Sc0.5)O3-PbTiO3 (BSF-PT) thin films by pulsed laser deposition, and the enhanced magnetic moment with respect to BiFeO3-PbTiO3. Dong-Gil Lee from Pusan National University, Korea, reports on the sterilization of enteropathogenic Escherichia coli using nanofiber TiO2 films prepared by the electrostatic spray method. Sang-Eun Park from the Korea Institute of Science and Technology reports on the study of encapsulated Fe3O4 nanoparticles with a silica thin layer with a reversible capacity of about 363 mAhg-1. Other researchers report on many other exiting achievements in the fields of ferromagnetic materials, magneto-optical materials, thermoelectric materials, shape memory materials, fuel-cell and

  19. Single nucleotide polymorphisms in an intergenic chromosome 2q region associated with tissue factor pathway inhibitor plasma levels and venous thromboembolism.

    PubMed

    Dennis, J; Truong, V; Aïssi, D; Medina-Rivera, A; Blankenberg, S; Germain, M; Lemire, M; Antounians, L; Civelek, M; Schnabel, R; Wells, P; Wilson, M D; Morange, P-E; Trégouët, D-A; Gagnon, F

    2016-10-01

    Essentials Tissue factor pathway inhibitor (TFPI) regulates the blood coagulation cascade. We replicated previously reported linkage of TFPI plasma levels to the chromosome 2q region. The putative causal locus, rs62187992, was associated with TFPI plasma levels and thrombosis. rs62187992 was marginally associated with TFPI expression in human aortic endothelial cells. Click to hear Ann Gil's presentation on new insights into thrombin activatable fibrinolysis inhibitor SUMMARY: Background Tissue factor pathway inhibitor (TFPI) regulates fibrin clot formation, and low TFPI plasma levels increase the risk of arterial thromboembolism and venous thromboembolism (VTE). TFPI plasma levels are also heritable, and a previous linkage scan implicated the chromosome 2q region, but no specific genes. Objectives To replicate the finding of the linkage region in an independent sample, and to identify the causal locus. Methods We first performed a linkage analysis of microsatellite markers and TFPI plasma levels in 251 individuals from the F5L Family Study, and replicated the finding of the linkage peak on chromosome 2q (LOD = 3.06). We next defined a follow-up region that included 112 603 single nucleotide polymorphisms (SNPs) under the linkage peak, and meta-analyzed associations between these SNPs and TFPI plasma levels across the F5L Family Study and the Marseille Thrombosis Association (MARTHA) Study, a study of 1033 unrelated VTE patients. SNPs with false discovery rate q-values of < 0.10 were tested for association with TFPI plasma levels in 892 patients with coronary artery disease in the AtheroGene Study. Results and Conclusions One SNP, rs62187992, was associated with TFPI plasma levels in all three samples (β = + 0.14 and P = 4.23 × 10 -6 combined; β = + 0.16 and P = 0.02 in the F5L Family Study; β = + 0.13 and P = 6.3 × 10 -4 in the MARTHA Study; β = + 0.17 and P = 0.03 in the AtheroGene Study), and contributed to the linkage peak in the F5L Family Study. rs

  20. Fall and its association with the frailty syndrome in the elderly: systematic review with meta-analysis.

    PubMed

    Fhon, Jack Roberto Silva; Rodrigues, Rosalina Aparecida Partezani; Neira, Wilmer Fuentes; Huayta, Violeta Magdalena Rojas; Robazzi, Maria Lucia do Carmo Cruz

    2016-01-01

    To analyze the prevalence of falls and frailty syndrome and the association between these two syndromes in the elderly population. Systematic review, without restriction of dates, in English, Portuguese and Spanish languages, in the databases PubMed, CINAHL, LILACS and in the SciElo virtual library. The association between both variables was extracted from the studies (Odds Ratio and 95% Confidence Intervals). The review included 19 studies published between 2001 and 2015. The prevalence of falls in the frail elderly population was between 6.7% and 44%; in the pre-frail, between 10.0% and 52.0%, and in the non-frail, between 7.6% and 90.4%. The association between both variables presented a value of OR 1.80 (95% CI 1.51-2.13). There is evidence that falls are associated to the frailty in the elderly. Other factors may influence this association, such as age, sex, data collection instrument of the studies, place where they live and the process of senescence. Analisar a prevalência de quedas e da síndrome da fragilidade e a associação entre essas duas síndromes na população idosa. Revisão sistemática, sem restrição de datas, nos idiomas inglês, português e espanhol, nas bases de dados PubMed, CINAHL, LILACS e na biblioteca virtual SciElo. A associação entre ambas as variáveis foi extraída dos próprios artigos (Odds Ratio e os Intervalos de Confiança de 95%). Foram incluídos na revisão 19 artigos publicados entre 2001 e 2015. A prevalência de queda no idoso frágil esteve entre 6,7% e 44%; nos pré-frágeis, entre 10,0% e 52,0%, e nos não frágeis, entre 7,6% e 90,4%. A associação entre ambas as variáveis apresentou o valor de OR 1,80 (IC 95% 1,51-2,13). Há evidências de que a queda está associada à fragilidade do idoso. Outros fatores podem influenciar essa associação, como idade, sexo, instrumento de coleta de dados dos estudos, local onde vive e o próprio processo de senescência.

  1. Effects of rock fragments on water dynamics in a fire-affected soil

    NASA Astrophysics Data System (ADS)

    Gordillo-Rivero, Ángel J.; García-Moreno, Jorge; Jordán, Antonio; Zavala, Lorena M.

    2014-05-01

    -Zapp, D., Poesen, J., Nearing, M.A. 2007. Effects of rock fragments incorporated in the soil matrix on concentrated flow hydraulics and erosion. Earth Surface Processes and Landforms 32, 1063-1076. Martínez-Zavala, L., Jordán, A., 2008. Effect of rock fragment cover on interrill soil erosion from bare soils in Western Andalusia, Spain. Soil Use and Management 24, 108, 117. DOI: 10.1111/j.1475-2743.2007.00139.x. Zavala, L.M., Jordán, A., Bellinfante, N., Gil, J. 2010. Relationships between rock fragment cover and soil hydrological response in a Mediterranean environment, Soil Science and Plant Nutrition 56, 95-104. DOI: 10.1111/j.1747-0765.2009.00429.x.

  2. Bam35 tectivirus intraviral interaction map unveils new function and localization of phage ORFan proteins.

    PubMed

    Berjón-Otero, Mónica; Lechuga, Ana; Mehla, Jitender; Uetz, Peter; Salas, Margarita; Redrejo-Rodríguez, Modesto

    2017-07-26

    Tectiviridae comprises a group of tail-less, icosahedral, membrane-containing bacteriophages that can be divided into two groups by their hosts, either Gram-negative or Gram-positive bacteria. While the first group is composed of PRD1 and nearly identical well characterized lytic viruses, the second one includes more variable temperate phages, like GIL16 or Bam35, whose hosts are Bacillus cereus and related Gram-positive bacteria.In the genome of Bam35, nearly half of the 32 annotated open reading frames (ORFs) have no homologs in databases (ORFans), being putative proteins of unknown function, which hinders the understanding of their biology. With the aim of increasing the knowledge of the viral proteome, we carried out a comprehensive yeast two-hybrid analysis among all the putative proteins encoded by the Bam35 genome. The resulting protein interactome comprises 76 unique interactions among 24 proteins, of which 12 have an unknown function. These results suggested that the P17 protein is the minor capsid protein of Bam35 and P24 is the penton protein, being the latter also supported by iterative threading protein modeling. Moreover, the inner membrane transglycosylase protein P26 could have an additional structural role. We also detected interactions involving non-structural proteins, such as the DNA binding protein P1 and the genome terminal protein (P4), which was confirmed by co-immunoprecipitation of recombinant proteins. Altogether, our results provide a functional view of the Bam35 viral proteome, with a focus on the composition and organization of the viral particle. IMPORTANCE Tail-less viruses of the family Tectiviridae can infect commensal and pathogenic Gram-positive and Gram-negative bacteria. Moreover, they have been proposed to be at the evolutionary origin of several groups of large eukaryotic DNA viruses and self-replicating plasmids. However, due to their ancient origin and complex diversity, many tectiviral proteins are ORFans of unknown

  3. Bam35 Tectivirus Intraviral Interaction Map Unveils New Function and Localization of Phage ORFan Proteins

    PubMed Central

    Berjón-Otero, Mónica; Lechuga, Ana; Mehla, Jitender; Uetz, Peter

    2017-01-01

    ABSTRACT The family Tectiviridae comprises a group of tailless, icosahedral, membrane-containing bacteriophages that can be divided into two groups by their hosts, either Gram-negative or Gram-positive bacteria. While the first group is composed of PRD1 and nearly identical well-characterized lytic viruses, the second one includes more variable temperate phages, like GIL16 or Bam35, whose hosts are Bacillus cereus and related Gram-positive bacteria. In the genome of Bam35, nearly half of the 32 annotated open reading frames (ORFs) have no homologs in databases (ORFans), being putative proteins of unknown function, which hinders the understanding of their biology. With the aim of increasing knowledge about the viral proteome, we carried out a comprehensive yeast two-hybrid analysis of all the putative proteins encoded by the Bam35 genome. The resulting protein interactome comprised 76 unique interactions among 24 proteins, of which 12 have an unknown function. These results suggest that the P17 protein is the minor capsid protein of Bam35 and P24 is the penton protein, with the latter finding also being supported by iterative threading protein modeling. Moreover, the inner membrane transglycosylase protein P26 could have an additional structural role. We also detected interactions involving nonstructural proteins, such as the DNA-binding protein P1 and the genome terminal protein (P4), which was confirmed by coimmunoprecipitation of recombinant proteins. Altogether, our results provide a functional view of the Bam35 viral proteome, with a focus on the composition and organization of the viral particle. IMPORTANCE Tailless viruses of the family Tectiviridae can infect commensal and pathogenic Gram-positive and Gram-negative bacteria. Moreover, they have been proposed to be at the evolutionary origin of several groups of large eukaryotic DNA viruses and self-replicating plasmids. However, due to their ancient origin and complex diversity, many tectiviral proteins are

  4. PREFACE: XV International Conference on Electrical Bio-Impedance (ICEBI) & XIV Conference on Electrical Impedance Tomography (EIT)

    NASA Astrophysics Data System (ADS)

    Pliquett, Uwe

    2013-04-01

    -Conference Tutorial Coordinator Uwe Pliquett International Advisory committee Kenneth R Foster, USA Sverre Grimnes, Norway David Holder, UK Alexander V Korjenewski, Russia Ørjan G Martinsen, Norway Mart Min, Estonia Stig Ollmar, Sweden Tadeusz Palko, Poland Pere J Riu, Spain Andrea Robitzki, Germany Hermann Scharfetter, Austria Leigh C Ward, Australia Conference logo Conference logo Sponsor logos Sponsor logos

  5. Impact of a prescribed fire on soil water repellency in a Banksia woodland (Western Australia)

    NASA Astrophysics Data System (ADS)

    Muñoz-Rojas, Miriam; Miller, Ben; Tangney, Ryan; Miller, Russell; González-Pérez, José A.; Jiménez-Morillo, Nicasio T.; Zavala, Lorena M.; Jordán, Antonio

    2016-04-01

    , Wittkuhn RS, McCaw L, Grierson PF. 2009. Long-term impacts of prescribed burning on regional extent and incidence of wildfires - evidence from 50 years of active fire management in sw australian forests. Forest Ecology and Management 259: 132-142. DOI: 10.1016/j.foreco.2009.10.005. Burrows ND, McCaw WL. 1990. Fuel characteristics and bushfire control in banksia low woodlands in western australia. Journal of Environmental Management 31: 229-236. DOI: 10.1016/S0301-4797(05)80036-2. Jordán A, Gordillo-Rivero AJ, García-Moreno J, Zavala LM, Granged AJP, Gil J, Neto-Paixão HM. 2014. Post-fire evolution of water repellency and aggregate stability in Mediterranean calcareous soils: A 6-year study. Catena 118:115-123. DOI: 10.1016/j.catena.2014.02.001. Lozano E, Jiménez-Pinilla P, Mataix-Solera J, Arcenegui V, Bárcenas GM, González-Pérez JA, García-Orenes F, Torres MP, Mataix-Beneyto J. 2013. Biological and chemical factors controlling the patchy distribution of soil water repellency among plant species in a Mediterranean semiarid forest. Geoderma 207-208:212-220. DOI: 10.1016/j.geoderma.2013.05.021. Muñoz-Rojas M, Erickson TE, Martini D, Dixon KW, Merritt DJ. 2016. Soil physicochemical and microbiological indicators of short, medium and long term post-fire recovery in semi-arid ecosystems. Ecological Indicators 63:14-22. DOI: 10.1016/j.ecolind.2015.11.038. Zavala LM, Jordán A, Gil J, Bellinfante N, Pain C. 2009. Intact ash and charred litter reduces susceptibility to rain splash erosion post-wildfire. Earth Surface Processes and Landforms 34: 1522-1532. DOI: 10.1002/esp.1837.

  6. Geochemistry of Aerosols in North -West India

    NASA Astrophysics Data System (ADS)

    Yadav, S.

    2001-12-01

    The geochemistry of, sources to, and transport of dust and their consequences on earth system processes are least understood. Here we follow Guru Gil's approach to use trace elements and isotopic data on aerosols in northwest India to understand their sources and processes. Aerosol samples were collected over a stretch of 550 kms from the Thar desert to the Delhi region which sits on the eastern fringe of the Thar. This region witnesses frequent dust storms in summer seasons due to high intensity south westerly and westerly winds. Major, trace elements including REE and Sr isotopic data are generated on three different group of aerosols such as dry deposition (DD, >100μm ), suspended particulate matter (SPM, 0.1-100μm ) and PM10 (<10μm ) collected by different sampling techniques and at different seasons. Major and trace elements in all DD samples show a high degree of homogeneity with similar LREE enriched patterns and -ve Eu anomalies regardless of space and time of sampling. These particles are geochemically similar to UCC, PAAS, and local loess with relatively low CIA values, indicating a low degree of chemical weathering suffered by their source regions dominated by upper crustal materials. Geochemistry of SPM and PM10 aerosols shows variation along the wind path. With decreasing size, crustal component decreases, anthropogenic inputs to transition metals and non-silicate input to Ca budget increase. The greater variability in finer fractions is primarily due to anthropogenic input and local meteorology where wind acts as an intensive variable. The REE patterns in SPM and PM10 are similar to DD samples with -ve Eu anomaly but their abundance decrease with size, probably due to some dilution effect by organics and mineralogical factors. It is possible that REE hosting minerals are concentrated in coarser silt and finest sand fractions (35-70μm ). This is supported by the decreasing Zr concentrations with decreasing size and distance in downwind direction

  7. An accurate density functional theory for the vapor-liquid interface of associating chain molecules based on the statistical associating fluid theory for potentials of variable range

    NASA Astrophysics Data System (ADS)

    Gloor, Guy J.; Jackson, George; Blas, Felipe J.; del Río, Elvira Martín; de Miguel, Enrique

    2004-12-01

    A Helmholtz free energy density functional is developed to describe the vapor-liquid interface of associating chain molecules. The functional is based on the statistical associating fluid theory with attractive potentials of variable range (SAFT-VR) for the homogenous fluid [A. Gil-Villegas, A. Galindo, P. J. Whitehead, S. J. Mills, G. Jackson, and A. N. Burgess, J. Chem. Phys. 106, 4168 (1997)]. A standard perturbative density functional theory (DFT) is constructed by partitioning the free energy density into a reference term (which incorporates all of the short-range interactions, and is treated locally) and an attractive perturbation (which incorporates the long-range dispersion interactions). In our previous work [F. J. Blas, E. Martín del Río, E. de Miguel, and G. Jackson, Mol. Phys. 99, 1851 (2001); G. J. Gloor, F. J. Blas, E. Martín del Río, E. de Miguel, and G. Jackson, Fluid Phase Equil. 194, 521 (2002)] we used a mean-field version of the theory (SAFT-HS) in which the pair correlations were neglected in the attractive term. This provides only a qualitative description of the vapor-liquid interface, due to the inadequate mean-field treatment of the vapor-liquid equilibria. Two different approaches are used to include the correlations in the attractive term: in the first, the free energy of the homogeneous fluid is partitioned such that the effect of correlations are incorporated in the local reference term; in the second, a density averaged correlation function is incorporated into the perturbative term in a similar way to that proposed by Toxvaerd [S. Toxvaerd, J. Chem. Phys. 64, 2863 (1976)]. The latter is found to provide the most accurate description of the vapor-liquid surface tension on comparison with new simulation data for a square-well fluid of variable range. The SAFT-VR DFT is used to examine the effect of molecular chain length and association on the surface tension. Different association schemes (dimerization, straight and branched chain

  8. V-type asteroids investigation in support to the NASA DAWN mission

    NASA Astrophysics Data System (ADS)

    de Sanctis, Maria Cristina; Migliorini, Alessandra; Lazzaro, Daniela; Luzia, Flavia; Ammannito, Eleonora; Capria, Maria Teresa; Filacchione, Gianrico; Mottola, Stefano; Boschin, Walter; Fiorenzano, Aldo; Ghinassi, Francesca

    4Vesta crust composition suggests that it has undergone extensive differentiation and resur-facing. It is the only large basaltic asteroid known at present (McCord, (1970); McFadden et al., (1977); Binzel, et al., (1997)), and it could be the smallest differentiated body of the Solar System. The NASA mission DAWN, launched on September 2007, is intended to deeper investigate the mineralogical properties of 4Vesta, in order to shed light on this puzzle (Russell et al., 2007). Although 4Vesta is the only large object in the Solar System which shows an almost intact basaltic crust, however an increasing number of small asteroids with a similar surface composition as 4Vesta were discovered thanks to ground-based telescopes (Xu et al., (1995); Burbine et al., (2001); Alvarez-Candal, et al. (2006)), posing the fundamental problem of the presence and distribution of basaltic material in the Solar System. Many of these asteroids were found to be spectrally and dynamically linked to 4Vesta, and they are known as the Vesta family. However, the scenario is much more complicated, because many Main Belt Asteroids, classified as V-type asteroids, were discovered near but not dynamically linked to 4Vesta. However, numerical simulations indicate that a relatively large fraction of the original Vesta family members may have evolved out of the family borders (Nesvorny et al., 2008); on the other hand, this seems not to be true for the low inclined asteroids, for which instead a different origin must be assumed. At present, more than 500 asteroids are classified as potentially V-type asteroids, thanks to new photometric investigation (Roig and Gil-Hutton, (2006); Roig et al., (2008); Moskoviz et al., (2008)). Some of these objects possibly belong to the Vesta-family, according to dynamical considerations, while other asteroids seem to be not clearly related to Vesta. Ground-based observations allow to investigate the spectral properties and hence the miner-alogical composition of

  9. A group contribution method for associating chain molecules based on the statistical associating fluid theory (SAFT-γ)

    NASA Astrophysics Data System (ADS)

    Lymperiadis, Alexandros; Adjiman, Claire S.; Galindo, Amparo; Jackson, George

    2007-12-01

    A predictive group-contribution statistical associating fluid theory (SAFT-γ) is developed by extending the molecular-based SAFT-VR equation of state [A. Gil-Villegas et al. J. Chem. Phys. 106, 4168 (1997)] to treat heteronuclear molecules which are formed from fused segments of different types. Our models are thus a heteronuclear generalization of the standard models used within SAFT, comparable to the optimized potentials for the liquid state OPLS models commonly used in molecular simulation; an advantage of our SAFT-γ over simulation is that an algebraic description for the thermodynamic properties of the model molecules can be developed. In our SAFT-γ approach, each functional group in the molecule is modeled as a united-atom spherical (square-well) segment. The different groups are thus characterized by size (diameter), energy (well depth) and range parameters representing the dispersive interaction, and by shape factor parameters (which denote the extent to which each group contributes to the overall molecular properties). For associating groups a number of bonding sites are included on the segment: in this case the site types, the number of sites of each type, and the appropriate association energy and range parameters also have to be specified. A number of chemical families (n-alkanes, branched alkanes, n-alkylbenzenes, mono- and diunsaturated hydrocarbons, and n-alkan-1-ols) are treated in order to assess the quality of the SAFT-γ description of the vapor-liquid equilibria and to estimate the parameters of various functional groups. The group parameters for the functional groups present in these compounds (CH3, CH2, CH3CH, ACH, ACCH2, CH2, CH , and OH) together with the unlike energy parameters between groups of different types are obtained from an optimal description of the pure component phase equilibria. The approach is found to describe accurately the vapor-liquid equilibria with an overall %AAD of 3.60% for the vapor pressure and 0.86% for

  10. Purification, kinetics, inhibitors and CD for recombinant β-amyrin synthase from Euphorbia tirucalli L and functional analysis of the DCTA motif, which is highly conserved among oxidosqualene cyclases.

    PubMed

    Ito, Ryousuke; Masukawa, Yukari; Hoshino, Tsutomu

    2013-03-01

    β-Amyrin, a natural triterpene, is widely distributed in the plant kingdom, and its pentacyclic skeleton is produced by oxidosqualene cyclase (OSC). OSC enzymes are classified as membrane proteins, and they catalyze the polycyclization reaction of (3S)-2,3-oxidosqualene to yield nearly 150 different cyclic triterpene skeletons. To date, no report has described the successful purification and characterization of plant β-amyrin synthase. The β-amyrin synthase from Euphorbia tirucalli (EtAS) was expressed as a polyhistidine-tagged protein in Saccharomyces cerevisiae GIL77, which lacks the lanosterol synthase gene. The expression yield, determined by western blotting analysis, was 5-7 mg. By Ni(2+) -nitrilotriacetic acid affinity column chromatography and careful selection of the proper imidazole concentration during the purification processes of washing and elution, a single band was successfully obtained on SDS/PAGE. We then tested the effects of four detergents on the enzyme activity. Supplementation with Triton X-100 at a concentration of 0.05% yielded the highest activity. The optimal pH and temperature were 7.0 and 30 °C, respectively. The kinetic parameters, K(m) and k(cat) , were determined to be 33.8 ± 0.53 μm and 46.4 ± 0.68 min(-1), respectively. To the best of our knowledge, there are no reports describing both K(m) and k(cat) for OSCs except for two examples of rat and bovine lanosterol synthases. The β-amyrin synthase purified in this study showed a significantly higher catalytic efficiency (k(cat)/K(m)) (~ 10(3)-fold) than those of the two reported lanosterol synthases. Gel-filtration HPLC indicated that the OSC exists as a monomer, and the eluted OSC retained its activity. Furthermore, the inhibition constants K(i) and IC(50) and types of inhibition by iminosqualene, Ro48-8071 and U18666A were determined, and indicated that iminosqualene and Ro48-8071 are potent inhibitors. Additionally, this is the first report of the kinetic data of the

  11. The 2017 Seventh World Congress of Paediatric Cardiology and Cardiac Surgery: "The Olympics of our Profession".

    PubMed

    Cohen, Mitchell I; Jacobs, Jeffrey P; Cicek, Sertac

    2017-12-01

    (2001), South America (2005), Australia (2009), Africa (2013), and Europe again (2017), in 2021, The World Congress of Paediatric Cardiology and Cardiac Surgery will be held for the first time in the continental United States. 1 The 8th World Congress of Paediatric Cardiology and Cardiac Surgery will be held in Washington DC, United States of America, 19-24 September, 2021, and will be organised by Jeffrey P. Jacobs and Gil Wernovsky. Mitchell I. Cohen served as the Scientific Program Co-Chair for the 2017 World Congress of Paediatric Cardiology and Cardiac Surgery, and he will again serve as the Scientific Program Co-Chair for the 2021 World Congress of Paediatric Cardiology and Cardiac Surgery along with Kathyrn Dodds RN, MSN, CRNP. Information about the upcoming 8th World Congress of Paediatric Cardiology and Cardiac Surgery can be found at www.WCPCCS2021.org.

  12. A group contribution method for associating chain molecules based on the statistical associating fluid theory (SAFT-gamma).

    PubMed

    Lymperiadis, Alexandros; Adjiman, Claire S; Galindo, Amparo; Jackson, George

    2007-12-21

    A predictive group-contribution statistical associating fluid theory (SAFT-gamma) is developed by extending the molecular-based SAFT-VR equation of state [A. Gil-Villegas et al. J. Chem. Phys. 106, 4168 (1997)] to treat heteronuclear molecules which are formed from fused segments of different types. Our models are thus a heteronuclear generalization of the standard models used within SAFT, comparable to the optimized potentials for the liquid state OPLS models commonly used in molecular simulation; an advantage of our SAFT-gamma over simulation is that an algebraic description for the thermodynamic properties of the model molecules can be developed. In our SAFT-gamma approach, each functional group in the molecule is modeled as a united-atom spherical (square-well) segment. The different groups are thus characterized by size (diameter), energy (well depth) and range parameters representing the dispersive interaction, and by shape factor parameters (which denote the extent to which each group contributes to the overall molecular properties). For associating groups a number of bonding sites are included on the segment: in this case the site types, the number of sites of each type, and the appropriate association energy and range parameters also have to be specified. A number of chemical families (n-alkanes, branched alkanes, n-alkylbenzenes, mono- and diunsaturated hydrocarbons, and n-alkan-1-ols) are treated in order to assess the quality of the SAFT-gamma description of the vapor-liquid equilibria and to estimate the parameters of various functional groups. The group parameters for the functional groups present in these compounds (CH(3), CH(2), CH(3)CH, ACH, ACCH(2), CH(2)=, CH=, and OH) together with the unlike energy parameters between groups of different types are obtained from an optimal description of the pure component phase equilibria. The approach is found to describe accurately the vapor-liquid equilibria with an overall %AAD of 3.60% for the vapor

  13. Habitus furibundo en el gueto estadounidense1

    PubMed Central

    Bourgois, Philippe; Castrillo, Fernando Montero; Hart, Laurie; Karandinos, George

    2014-01-01

    necesitados de fuerte medicación farmacéutica. La mejor manera de asegurar la continuidad de este frágil subsidio resulta ser los estallidos periódicos de violencia autoinfligida. Simultáneamente, con la anuencia de la mano derecha del Estado, en las cárceles violentas y hacinadas marcadas por formas hostiles de supervisión, la furia se convierte en una valiosa estrategia de protección física para los internos. En resumen, la violencia expresiva se convierte en una base práctica para el sostenimiento económico y para forjar el sentido de dignidad entre hombres y mujeres. PMID:24532976

  14. PREFACE: Symmetry and Structural Properties of Condensed Matter

    NASA Astrophysics Data System (ADS)

    Lulek, Tadeusz; Wal, Andrzej; Lulek, Barbara

    2008-03-01

    tradition. We would also like to acknowledge the support of European Physical Society. On behalf of the organizers of SSPCM 2007 Tadeusz Lulek, Andrzej Wal and Barbara Lulek Editors

  15. PREFACE: Loops 11: Non-Perturbative / Background Independent Quantum Gravity

    NASA Astrophysics Data System (ADS)

    Mena Marugán, Guillermo A.; Barbero G, J. Fernando; Garay, Luis J.; Villaseñor, Eduardo J. S.; Olmedo, Javier

    2012-05-01

    Netherlands), Jacek Puchta (Centre de Physique Théorique de Luminy, Marseille, France), James Ryan (Albert Einstein Institute, Potsdam, Germany), Lorenzo Sindoni (Albert Einstein Institute, Golm, Germany), David Sloan (Institute for Theoretical Physics, Utrecht University, The Netherlands), Johannes Tambornino (Laboratoire de Physique, ENS Lyon, France), Andreas Thurn (Institute for Theoretical Physics III, FAU Erlangen Nürnberg, Germany), Francesca Vidotto (Laboratoire de Physique Subatomique et de Cosmologie, Grenoble, France), and Matteo Smerlak (Albert Einstein Institute, Golm, Germany). We would like to conclude this preamble by thanking all the attendants of the conference for their high and enthusiastic participation. The presence of a large number of past and present Loop Quantum Gravity practitioners, as well as a significant number of top researchers in other approaches to quantum gravity, provided ample opportunities for fruitful scientific exchanges and a very lively atmosphere. It is encouraging to see that, 25 years after the inception of Loop Quantum Gravity, there is a vibrant young community of researchers entering the field. Let us hope that, with their help, the quantization of general relativity can be successfully accomplished in the near future. The Editors Conference photograph

  16. Editorial: Focus on Dynamics and Thermalization in Isolated Quantum Many-Body Systems

    NASA Astrophysics Data System (ADS)

    Cazalilla, M. A.; Rigol, M.

    2010-05-01

    interaction quenches in the Hubbard model: prethermalization and non-equilibrium dynamics Michael Moeckel and Stefan Kehrein Quantum quenches in integrable field theories Davide Fioretto and Giuseppe Mussardo Dynamical delocalization of Majorana edge states by sweeping across a quantum critical point A Bermudez, L Amico and M A Martin-Delgado Thermometry with spin-dependent lattices D McKay and B DeMarco Near-adiabatic parameter changes in correlated systems: influence of the ramp protocol on the excitation energy Martin Eckstein and Marcus Kollar Sudden change of the thermal contact between two quantum systems J Restrepo and S Camalet Reflection of a Lieb-Liniger wave packet from the hard-wall potential D Jukić and H Buljan Probing interaction-induced ferromagnetism in optical superlattices J von Stecher, E Demler, M D Lukin and A M Rey Sudden interaction quench in the quantum sine-Gordon model Javier Sabio and Stefan Kehrein Dynamics of an inhomogeneous quantum phase transition Jacek Dziarmaga and Marek M Rams

  17. Evaluation of Pump Pulsation in Respirable Size-Selective Sampling: Part II. Changes in Sampling Efficiency

    PubMed Central

    Lee, Eun Gyung; Lee, Taekhee; Kim, Seung Won; Lee, Larry; Flemmer, Michael M.; Harper, Martin

    2015-01-01

    This second, and concluding, part of this study evaluated changes in sampling efficiency of respirable size-selective samplers due to air pulsations generated by the selected personal sampling pumps characterized in Part I (Lee E, Lee L, Möhlmann C et al. Evaluation of pump pulsation in respirable size-selective sampling: Part I. Pulsation measurements. Ann Occup Hyg 2013). Nine particle sizes of monodisperse ammonium fluorescein (from 1 to 9 μm mass median aerodynamic diameter) were generated individually by a vibrating orifice aerosol generator from dilute solutions of fluorescein in aqueous ammonia and then injected into an environmental chamber. To collect these particles, 10-mm nylon cyclones, also known as Dorr-Oliver (DO) cyclones, were used with five medium volumetric flow rate pumps. Those were the Apex IS, HFS513, GilAir5, Elite5, and Basic5 pumps, which were found in Part I to generate pulsations of 5% (the lowest), 25%, 30%, 56%, and 70% (the highest), respectively. GK2.69 cyclones were used with the Legacy [pump pulsation (PP) = 15%] and Elite12 (PP = 41%) pumps for collection at high flows. The DO cyclone was also used to evaluate changes in sampling efficiency due to pulse shape. The HFS513 pump, which generates a more complex pulse shape, was compared to a single sine wave fluctuation generated by a piston. The luminescent intensity of the fluorescein extracted from each sample was measured with a luminescence spectrometer. Sampling efficiencies were obtained by dividing the intensity of the fluorescein extracted from the filter placed in a cyclone with the intensity obtained from the filter used with a sharp-edged reference sampler. Then, sampling efficiency curves were generated using a sigmoid function with three parameters and each sampling efficiency curve was compared to that of the reference cyclone by constructing bias maps. In general, no change in sampling efficiency (bias under ±10%) was observed until pulsations exceeded 25% for the

  18. Evaluation of pump pulsation in respirable size-selective sampling: part II. Changes in sampling efficiency.

    PubMed

    Lee, Eun Gyung; Lee, Taekhee; Kim, Seung Won; Lee, Larry; Flemmer, Michael M; Harper, Martin

    2014-01-01

    This second, and concluding, part of this study evaluated changes in sampling efficiency of respirable size-selective samplers due to air pulsations generated by the selected personal sampling pumps characterized in Part I (Lee E, Lee L, Möhlmann C et al. Evaluation of pump pulsation in respirable size-selective sampling: Part I. Pulsation measurements. Ann Occup Hyg 2013). Nine particle sizes of monodisperse ammonium fluorescein (from 1 to 9 μm mass median aerodynamic diameter) were generated individually by a vibrating orifice aerosol generator from dilute solutions of fluorescein in aqueous ammonia and then injected into an environmental chamber. To collect these particles, 10-mm nylon cyclones, also known as Dorr-Oliver (DO) cyclones, were used with five medium volumetric flow rate pumps. Those were the Apex IS, HFS513, GilAir5, Elite5, and Basic5 pumps, which were found in Part I to generate pulsations of 5% (the lowest), 25%, 30%, 56%, and 70% (the highest), respectively. GK2.69 cyclones were used with the Legacy [pump pulsation (PP) = 15%] and Elite12 (PP = 41%) pumps for collection at high flows. The DO cyclone was also used to evaluate changes in sampling efficiency due to pulse shape. The HFS513 pump, which generates a more complex pulse shape, was compared to a single sine wave fluctuation generated by a piston. The luminescent intensity of the fluorescein extracted from each sample was measured with a luminescence spectrometer. Sampling efficiencies were obtained by dividing the intensity of the fluorescein extracted from the filter placed in a cyclone with the intensity obtained from the filter used with a sharp-edged reference sampler. Then, sampling efficiency curves were generated using a sigmoid function with three parameters and each sampling efficiency curve was compared to that of the reference cyclone by constructing bias maps. In general, no change in sampling efficiency (bias under ±10%) was observed until pulsations exceeded 25% for the

  19. Influence of biological soil crusts at different successional stages in the implantation of biogeochemical cycles in arid and semiarid zones

    NASA Astrophysics Data System (ADS)

    Gil-Sotres, F.; Miralles, I.; Canton-Castilla, Y.; Domingo, F.; Leiros, M. C.; Trasar-Cepeda, C.

    2012-04-01

    Influence of biological soil crusts at different successional stages in the implantation of biogeochemical cycles in arid and semiarid zones I. Miralles1, F. Gil-Sotres2, Y. Cantón-Castilla3, F. Domingo1, M.C. Leirós2, C. Trasar-Cepeda4 1 Experimental Estation of Arid Zones (CSIC), E-04230 La Cañada de San Urbano, Almería, Spain. 2 Departamento Edafología y Química Agrícola, Grupo de Evaluación de la Calidad del Suelo, Unidad Asociada CSIC, Facultad de Farmacia, Universidad de Santiago de Compostela, E-15782 Santiago de Compostela, Spain. 3 University of Almería, Departamento de Edafología y Química Agrícola, E-04230-La Cañada de San Urbano, Almería, Spain. 4 Departamento Bioquímica del Suelo, IIAG-CSIC, Apartado 122, E-15708 Santiago de Compostela, Spain. Crusts (BSCs) are formed by a close association between soil particles and cyanobacteria, algae, lichens, bryophytes and microfungi in varying proportions. Their habitat is within or immediately on top of the uppermost millimetres of the soil and are the predominant surface cover in arid and semiarid zones. Among the diverse functions developed by BSCs in the ecosystem (hydrology, erosion, soil properties, etc.), one of the most important is its role in nutrient cycling. Within arid and semiarid environments, BSCs have been termed 'mantles of fertility' being considered hotspots of biogeochemical inputs, fixing C, N and P above- and below-ground. However, there are differences in N and C fixation rates between BSCs types. Early successional BSCs, dominated by cyanobacterial species, fix lower quantities of C and N than mature BSCs dominated by lichens. Although the positive effects of BSCs on biogeochemical soil cycles are widely accepted, no previous studies have evaluated the activities of the enzymes involved in C, N and P cycles of BSCs and how they are affected by the successional stage of the BSC. In this work, performed in the Tabernas desert (SE Spain), we studied the hydrolase enzymes

  20. Eddy covariance N2O flux measurements at low flux rates: results from the InGOS campaign in a Danish willow field.

    NASA Astrophysics Data System (ADS)

    Ibrom, Andreas; Brümmer, Christian; Hensen, Arjan; van Asperen, Hella; Carter, Mette S.; Gasche, Rainer; Famulari, Daniela; Kutsch, Werner; Pilegaard, Kim; Ambus, Per

    2014-05-01

    Nitrous oxide (N2O) fluxes from soils are characterised by their high spatial and temporal variability. The fluxes depend on the availability of the substrates for nitrification and denitrification and soil physical and chemical conditions that control the metabolic microbial activity. The sporadic nature of the fluxes and their high sensitivity to alterations of the soil climate put very high demands on measurement approaches. Laser spectroscopy enables accurate and fast response detection of atmospheric N2O concentrations and is used for eddy covariance (EC) flux measurements. Alternatively N2O fluxes can be measured with chambers together with high precision analysers. Differences in the measurement approaches and system designs are expected to have a considerable influence on the accuracy of the flux estimation. This study investigates how three different eddy covariance systems perform in a situation of low N2O fluxes from a flat surface. Chamber flux measurements with differing chamber and analyser designs are used for comparison. In April 2013, the EU research infrastructure project InGOS (http://www.ingos-infrastructure.eu/) organised a campaign of N2O flux measurements in a willow plantation close to the Risø Campus of the Technical University of Denmark. The willow field was harvested in February 2013 and received mineral fertiliser equivalent to 120 kg N ha-1 before the campaign started. Three different eddy covariance systems took part in the campaign: two Aerodyne quantum cascade laser (QCL) based systems and one Los Gatos Research off-axis integrated-cavity-output spectroscopy (ICOS) system for N2O and CO. The sonic anemometers were all installed at 2 m height above the bare ground. Gill R3 type sonic anemometers were used with QCL systems and a Gil HS-50 with the ICOS system. The 10 Hz raw data were analysed with group specific softwares and procedures. The local conditions in the exceptionally cold and dry spring 2013 did not lead to large N2O flux

  1. The University of Alcala de Henares (madrid, Spain), as a Dynamic Example and Laboratory of the Recovery, Rehabilitation, and Conservation of the Cultural Heritage

    NASA Astrophysics Data System (ADS)

    Echeverría Valiente, E.; da Casa Martín, F.; Celis D'amicoa, F.; Navarro, P. C.

    2013-07-01

    Cardinal Cisneros launched in 1499 a major universitary project, that was located in Alcala de Henares (Madrid, Spain). It bestowed recently the recognition of the Council of Europe as a World Heritage Site in 1998 by UNESCO. Cisneros created the new university in the vicinity of the Roman town of Complutum. This site had two qualities which were particularly important: it was placed at a safe distance from the power of the Crown at Toledo, and it was well connected with other main Spanish cities, through the Roman road or calzada that crossed the Iberian peninsula from South to North going along some important settlements as Mérida, Toledo, Zaragoza, and Barcelona. Thus the old town of Alcala de Henares still keeps the remains of the Visigothic, Roman, Muslim and Hebrew cultures. Since the end of the fifteenth century the built Renaissance complex has gone through three clear stages, where lots of relevant architects developed their work. Among them, Pedro Gumiel and Rodrigo Gil de Hontañón can be cited for their first drawings, but other anonymous architects have also contributed to build such an interesting project. In a second stage some repairs were needed on the former structures, in order to adapt them to their new functions due to deterioration or even to changes in ownership or uses (as happened to the Colegio Mayor de San Ildefonso). Finally, at the latest stage at the end of the 20th and the early 21st centuries a new regeneration project took place in order to introduce the modern technologies and energy-efficient standards the old universitary buildings. An interesting example of this modern practices on dynamic conservation of the historical heritage is the new Learning and Research Center (LRC) on the ruins of San Diego headquarter built in 1859 on the site of the Franciscan convent of Santa Maria de Jesus, founded in 1445 by Archbishop Alonso Carrillo (which in turn it replaced an earlier one). The aims of the new LRC are to, preserve and

  2. History of education in medicine and surgery, first hospitals development of urology in danzig/Gdańsk.

    PubMed

    Zajączkowski, Tadeusz

    2014-01-01

    origins in the Chair of Anatomy and Medicine at Danzig Academic Gymnasium (GA; Sive Illustre), an establishment which lasted for 239 years, from 1584 to 1812. The history of surgery in Danzig has its roots in the centuries-old tradition of the medical practice of surgeons who were associated in the Surgeons Guild, teaching, as well medical and scientific research. The Surgeons Guild existed in Danzig from 1454 to 1820. Over the centuries manual intervention was also in the hands of academically uneducated persons such as bath house attendants, barbers, and wandering surgeons. Until the end of 1946 there was no separate urology department in Danzig. Urological surgery was in the hands of surgeons. Interventions and operations on genitourinary organs were carried out, more or less, in all surgical departments. The end of World War II created a new political situation in Europe. Danzig (now Gdafisk) and Pomerania became part of Poland. In 1945, on the basis of the former MAD, the Polish Government established the Polish Academy of Physicians, later renamed the Medical Academy in Gdafisk (Gdafiska Akademia Medyczna - GAM). In 2009, GAM was again renamed, as the Medical University of Gdafisk (Gdaiski Uniwersytet Medyczny). The political changes after World War II accelerated the process of the separation of urology from surgery. In May 1947, a 30-bed Urological Ward was opened in Gdanisk, in Debinki Street, forming part of the First Surgical Clinic of the Academy of Physicians (headed by Prof. Kornel Michejda, 1887-1960, later by Prof. Stanislaw Nowicki, 1893-1972, and lastly by Prof. Zdzislaw Kieturakis, 1904-1971). The first head doctor of the new urological ward was Dr. Tadeusz L$renz (1906-1986), a urologist from Lvov (Lemberg). After the departure of Professor Lorenz to Wrodclaw (Breslau) in 1958, Dr. Jan Renkielski was acting as Head of the Urological Ward until 1971. In 1971 the ward was transformed to the separate Department of Urology. Docent ("lecturer"), and later

  3. Irrigation scheduling of green areas based on soil moisture estimation by the active heated fiber optic distributed temperature sensing AHFO

    NASA Astrophysics Data System (ADS)

    Zubelzu, Sergio; Rodriguez-Sinobas, Leonor; Sobrino, Fernando; Sánchez, Raúl

    2017-04-01

    min were applied uniformly along the fiber optic cable and the thermal response on an adjacent cable was monitored prior, during and after the irrigation event. Data was logged every 0.3 m and every 5 s then, the heating and drying phase integer (called Tcum) was determined following the approach of Sayde et al., (2010). Thus, the infiltration and redistribution of soil water content was fully characterized. The results are promising since the water spatial variability within the soil is known and it can be correlated with the water distribution in the irrigation unit to make better irrigation scheduling in the green area improving water/nutrient/energy efficiency.. Reference Létourneau, G., Caron, J., Anderson, L., & Cormier, J. (2015). Matric potential-based irrigation management of field-grown strawberry: Effects on yield and water use efficiency. Agricultural Water Management, 161, 102-113. Liang, X., Liakos, V., Wendroth, O., & Vellidis, G. (2016). Scheduling irrigation using an approach based on the van Genuchten model. Agricultural Water Management, 176, 170-179. Sayde,C., Gregory, C., Gil-Rodriguez, M., Tufillaro, N., Tyler, S., van de Giesen, N., English, M. Cuenca, R. and Selker, J. S.. 2010. Feasibility of soil moisture monitoring with heated fiber optics. Water Resources Research. Vol.46 (6). DOI: 10.1029/2009WR007846 Stirzaker, R. J., Maeko, T. C., Annandale, J. G., Steyn, J. M., Adhanom, G. T., & Mpuisang, T. (2017). Scheduling irrigation from wetting front depth. Agricultural Water Management, 179, 306-313.

  4. Management of postoperative pain in abdominal surgery in Spain. A multicentre drug utilization study

    PubMed Central

    Vallano, Antonio; Aguilera, Cristina; Arnau, Josep Maria; Baños, Josep-Eladi; Laporte, Joan-Ramon

    1999-01-01

    Participating centres: Hospital Universitario San Juan, Alicante: Maria Jesús Olaso, Javier Agulló, Clara Faura. Hospital Torrecárdenas, Almería: Carmen Fernández Sánchez, Miguel Lorenzo Campos, Juan Manuel Rodríguez Alonso. Hospital Quirúrgic Adriano, Barcelona: Carmen Alerany Pardo, Paquita Alvarez González, Teresa Martín Benito. Hospital Universitari del Mar-IMIM, Barcelona: Magí Farré, Maite Terán. Corporació Sanitària Parc Taulí, Sabadell: Montserrat Cañellas, Sergio Zavala, Josep Planell. Hospital Universitari de la Santa Creu i Sant Pau: Gonzalo Calvo, Rosa Morros, Silvia Mateo. Hospital General Vall d’Hebron, Barcelona: Carmen Bosch, María José Martínez. Hospital Universitario Virgen de la Victoria, Málaga: Maribel Lucena, José Antonio González, Gabriel Carranque. Hospital Clínico Universitario San Carlos, Madrid: Emilio Vargas, Amparo Gil López-Oliva, Míriam García Mateos. Hospital Universitario Marqués de Valdecilla, Santander: Mario González, Antonio Cuadrado. Hospital Universitario Virgen de la Macarena, Sevilla: Juan Antonio Durán, Pilar Máyquez, María Isabel Serrano. Hospital Universitario Virgen del Rocío, Sevilla: Jaume Torelló, Juan Ramón Castillo, María de las Nieves Merino. Aims Postoperative pain is common in hospital-admitted patients. Its management is determined by different therapeutic traditions and by the attitudes of health professionals in each hospital. The aim of this study was to describe the patterns of prescription and administration of analgesic drugs used for postoperative pain after abdominal surgery in Spanish hospitals, to know the prevalence and the severity of postoperative pain, and to determine the extent of variability in the management of postoperative pain among the participating centres. Methods The study was a multicentre descriptive cross-sectional drug utilization study in 12 Spanish hospitals. The subjects were an unselected sample of consecutive patients undergoing abdominal

  5. Study of the impact of cyclogenesis at the Mediterranean Sea

    NASA Astrophysics Data System (ADS)

    Ribo, M.; Llasat, C.

    2009-09-01

    cyclones, from weak mesoscale depressions to strong, intense and more extensive depressions, and are classified using different criteria. In our study each cyclone identified was characterized using two dynamic criteria: vertical structure and geostrophic circulation. The first characterization is based on the vertical profiles of the laplacian of temperature, depending on which atmospheric level is reached by the cyclone. The second characterization is based on the geostrophic circulation, defined with the geostrophic vorticity in the cyclone domain. From these two characterizations, we have classified the cyclonic centers into six different types: deep, medium and shallow; strong, moderate and weak cyclones. Results show that between 1990 and 2004, 25% of the days in this time period have recorded a flood event in the Mediterranean Basin, and 90.7% of these flood events were related to a cyclonic center. 57% of these events had been located at the western Mediterranean part, although some flood prone areas can be identified in all the Mediterranean Basin; Eastern Spain and Balearic Islands, northern of Italy (gulf of Genève), north of Africa (Sahara) and Cyprus and Turkey. Cyclones related with floods in the western part are mainly superficial cyclones. An important nucleus of deep cyclones related with floods can be found near Cyprus. The spatial distribution of cyclones related with floods, for the period from 1990 to 2004, is coherent with the general distribution of cyclones showed by Gil et al. 2002. There is a general tendency of increase of detected flood events with cyclonic center in the vicinity in the time period analyzed. A total of 4724 victims where counted during flood episodes. Results of the relationship between flood episodes and cyclonic centers show that 40% of the flood episodes with higher damages were related to weak cyclones.

  6. Vegetation cover and land use impacts on soil water repellency in an Urban Park located in Vilnius, Lithuania

    NASA Astrophysics Data System (ADS)

    Pereira, Paulo; Cerda, Artemi

    2015-04-01

    soil. The soils from Pine, Birch, Penduculate Oak, forest trails and planted grass were majorly severely water repellent, while Platanus soils were mostly strong water repellent. Soil water repellency of Pine soils had a significant negative correlation with pH (-0.52, p<0.05) and a significant negative correlation with SOM (0.69, p<0.01) and EC (0.53, p<0.05). In relation to Birch soils, SWR had a significant negative correlation with pH (-0.88, p<0.001) and significant positive correlation with SOM (0.78, p<0.001). In relation to the other species no significant correlations were observed between SWR and pH, EC and SOM. Acknowledgments POSTFIRE (Soil quality, erosion control and plant cover recovery under different post-fire management scenarios, CGL2013-47862-C2-1-R), funded by the Spanish Ministry of Economy and Competitiveness; Fuegored; RECARE (Preventing and Remediating Degradation of Soils in Europe Through Land Care, FP7-ENV-2013-TWO STAGE), funded by the European Commission; and for the COST action ES1306 (Connecting European connectivity research). References Bisdom, E.B.A., Dekker, L., Schoute, J.F.Th. (1993) Water repellency of sieve fractions from sandy soils and relationships with organic material and soil structure. Geoderma, 56, 105-118. Doerr, S.H., Shakesby, R.A., Walsh, R.P.D. (2000) Soil water repellency: Its causes, characteristics and hydro-geomorphological significance. Earth-Science Reviews, 51, 33-65. Doerr, S.H. (1998) On standardising the "Water Drop Penetration Time" and the "Molarity of an Ethanol Droplet" techniques to classify soil hydrophobicity: a case study using medium textured soils. Earth Surface Process and Landforms, 23, 663-668. Mataix-Solera, J., Arcenegui, V., Zavala, L., Perez-Bejarano, A., Jordan, A., Morugan-Coronado, A., Barcenas-Moreno, G., Jimenez-Pinilla, P., Lozano, E., Granjed, A.J.P., Gil-Torres, J. (2014) Small variations of soil properties control fire induced water repellency, Spanish Journal of Soil Science, 4

  7. Organic amendments as restoration techniques in degraded arid and semiarid systems: A review

    NASA Astrophysics Data System (ADS)

    Hueso-González, Paloma; Muñoz-Rojas, Miriam

    2017-04-01

    common doses and, (3) risk derivates for their application. References: Guerrero, C., Gómez, I., Moral, R., Mataix-Solera, J., Mataix-Beneyto, J., Hernández, T.: Reclamation of a burned forest soil with municipal waste compost: macronutrient dynamic and improved vegetation cover recovery, Bioresource Technology, 76, 221-227, 2001. Hueso-González, P., Martínez-Murillo, J.F., and Ruiz Sinoga., J.D.: The impact of organic amendments on forest soil properties under Mediterranean climatic conditions, Land Degradation and Development, 25, 604-612, 2014. Hueso-González, P., Martínez-Murillo, J.F., and Ruiz Sinoga., J.D.: Effects of topsoil treatments on afforestation in a dry-Mediterranean climate (Southern Spain), Solid Earth, 7, 1479-1489, 2016. Hueso-González, P., Ruíz Sinoga, J.D., Martínez-Murillo, J.F., and Lavee, H.: Overland flow generation mechanisms affected by topsoil treatment: Application to soil conservation, Geomorphology, 228, 796-804, 2015. Jordán, A., Zavala, L.M., Gil, J.: Effects of mulching on soil physical properties and runoff under semi-arid conditions in southern Spain, Catena 81, 77-85, 2010. Jordán, A., Zavala, L.M., Muñoz-Rojas, M. 2011. Mulching, effects on soil physical properties. In: Glinski, J., Horabik, J., Lipiec, J. (Eds.), Encyclopedia of Agrophysics. Springer, Berlin, pp. 492-496. Lal R.: Soils and sustainable agriculture. A review, Agron. Sustain. Dev. 28, 57-64, 2008. Muñoz-Rojas, M., Erickson, T.E., Dixon, K.W., Merritt, D.J.: Soil quality indicators to assess functionality of restored soils in degraded semiarid ecosystems, Restor. Ecol., 2016a. Muñoz-Rojas, M., Erickson, T.E., Martini, D., Dixon, K.W., Merritt, D.J.: Soil physicochemical and microbiological indicators of short, medium and long term post-fire recovery in semi-arid ecosystems, Ecol. Indic., 63,14-22, 2016b. Muñoz-Rojas, M., Erickson, T.E., Martini, D., Dixon, K.W., Merritt, D.J.: Climate and soil factors influencing seedling recruitment of plant species

  8. Ground-penetrating radar investigation of St. Leonard's Crypt under the Wawel Cathedral (Cracow, Poland) - COST Action TU1208

    NASA Astrophysics Data System (ADS)

    Benedetto, Andrea; Pajewski, Lara; Dimitriadis, Klisthenis; Avlonitou, Pepi; Konstantakis, Yannis; Musiela, Małgorzata; Mitka, Bartosz; Lambot, Sébastien; Żakowska, Lidia

    2016-04-01

    The Wawel ensemble, including the Royal Castle, the Wawel Cathedral and other monuments, is perched on top of the Wawel hill immediately south of the Cracow Old Town, and is by far the most important collection of buildings in Poland. St. Leonard's Crypt is located under the Wawel Cathedral of St Stanislaus BM and St Wenceslaus M. It was built in the years 1090-1117 and was the western crypt of the pre-existing Romanesque Wawel Cathedral, so-called Hermanowska. Pope John Paul II said his first Mass on the altar of St. Leonard's Crypt on November 2, 1946, one day after his priestly ordination. The interior of the crypt is divided by eight columns into three naves with vaulted ceiling and ended with one apse. The tomb of Bishop Maurus, who died in 1118, is in the middle of the crypt under the floor; an inscription "+ MAVRVS EPC MCXVIII +" indicates the burial place and was made in 1938 after the completion of archaeological works which resulted in the discovery of this tomb. Moreover, the crypt hosts the tombs of six Polish kings and heroes: Michał Korybut Wiśniowiecki (King of the Polish-Lithuanian Commonwealth), Jan III Sobieski (King of the Polish-Lithuanian Commonwealth and Commander at the Battle of Vienna), Maria Kazimiera (Queen of the Polish-Lithuanian Commonwealth and consort to Jan III Sobieski), Józef Poniatowski (Prince of Poland and Marshal of France), Tadeusz Kościuszko (Polish general, revolutionary and a Brigadier General in the American Revolutionary War) and Władysław Sikorski (Prime Minister of the Polish Government in Exile and Commander-in-Chief of the Polish Armed Forces). The adjacent six crypts and corridors host the tombs of the other Polish kings, from Sigismund the Old to Augustus II the Strong, their families and several Polish heroes. In May 2015, the COST (European COoperation in Science and Technology) Action TU1208 "Civil engineering applications of Ground Penetrating Radar" organised and offered a Training School (TS) on the

  9. Intervening factors for the initiation of treatment of patients with stomach and colorectal cancer.

    PubMed

    Valle, Thaína Dalla; Turrini, Ruth Natalia Teresa; Poveda, Vanessa de Brito

    2017-05-15

    ção de acompanhamento preventivo (p<0,001) estiveram associados a menores períodos entre a busca por assistência e início do tratamento. Naúsea, vômito, hematoquesia, perda ponderal e dor foram associados à procura mais ágil por assistência. o maior intervalo entre a busca por assistência médica e o diagnóstico ocorreu, possivelmente, pela não associação entre os sintomas apresentados e a doença. identificar el tiempo entre los síntomas, la búsqueda de asistencia y el inicio del tratamiento en pacientes con cáncer gástrico y colorrectal y los factores que interfieren en estos procesos. estudio descriptivo correlacional, incluyendo 101 pacientes con diagnostico de cáncer gástrico o colorrectal, atendidos en un hospital especializado en oncología. de 101 pacientes investigados la mayoria eran hombres, con edad media de 61,7 años. La búsqueda de la atención médica se produjo dentro de los 30 días después de la aparición de los síntomas, en la mayoría de los casos. El promedio de tiempo total entre el inicio de los síntomas y el inicio del tratamiento fue de 15,16 meses y el tiempo medio entre la búsqueda de la atención médica y el diagnóstico fue de 4,78 meses. La historia familiar de cáncer (p=0,008) y la realización de seguimiento preventivo (p<0,001) se asociaron con períodos más cortos entre la búsqueda de la atención y el tratamiento temprano. Náuseas, vómitos, hematoquecia, pérdida de peso y dolor se asociaron con la búsqueda más rápida de la asistencia. el intervalo más largo entre la búsqueda de la atención médica y el diagnóstico se produjo posiblemente por asociación negativa entre los síntomas que se presentan y las enfermedades.

  10. EDITORIAL: Focus on Quantum Control

    NASA Astrophysics Data System (ADS)

    Rabitz, Herschel

    2009-10-01

    Control of quantum phenomena has grown from a dream to a burgeoning field encompassing wide-ranging experimental and theoretical activities. Theoretical research in this area primarily concerns identification of the principles for controlling quantum phenomena, the exploration of new experimental applications and the development of associated operational algorithms to guide such experiments. Recent experiments with adaptive feedback control span many applications including selective excitation, wave packet engineering and control in the presence of complex environments. Practical procedures are also being developed to execute real-time feedback control considering the resultant back action on the quantum system. This focus issue includes papers covering many of the latest advances in the field. Focus on Quantum Control Contents Control of quantum phenomena: past, present and future Constantin Brif, Raj Chakrabarti and Herschel Rabitz Biologically inspired molecular machines driven by light. Optimal control of a unidirectional rotor Guillermo Pérez-Hernández, Adam Pelzer, Leticia González and Tamar Seideman Simulating quantum search algorithm using vibronic states of I2 manipulated by optimally designed gate pulses Yukiyoshi Ohtsuki Efficient coherent control by sequences of pulses of finite duration Götz S Uhrig and Stefano Pasini Control by decoherence: weak field control of an excited state objective Gil Katz, Mark A Ratner and Ronnie Kosloff Multi-qubit compensation sequences Y Tomita, J T Merrill and K R Brown Environment-invariant measure of distance between evolutions of an open quantum system Matthew D Grace, Jason Dominy, Robert L Kosut, Constantin Brif and Herschel Rabitz Simplified quantum process tomography M P A Branderhorst, J Nunn, I A Walmsley and R L Kosut Achieving 'perfect' molecular discrimination via coherent control and stimulated emission Stephen D Clow, Uvo C Holscher and Thomas C Weinacht A convenient method to simulate and visually

  11. PREFACE: Workshop Photograph and Program

    NASA Astrophysics Data System (ADS)

    2011-07-01

    : Bonnie Fleming (Yale U.))18:30 Supernovae neutrino detection (20') Ines Gil-Botella (CIEMAT)18:50 Neutrino cross-section in Liquid Argon in the GeV range (15') Flavio Cavanna (U. of L'Aquila)19:05 Analysis of the ArgoNeuT neutrino data (15') Carl Bromberg (Michigan State U.)19:20 Neutrino event reconstruction (15') Gary Barker (U. of Warwick) Tuesday 30 March 2010Ways to improve the Liquid Argon Charge Imaging technology I (Chair: Christos Touramanis (U. of Liverpool))09:00 Liquid Argon LEM TPC (30') Filippo Resnati (ETH Zurich)09:30 Micromegas for charge readout of double phase liquid Argon large TPCs (20') Alain Delbart (Saclay)09:50 Development of Thick-GEMs for GEM-TPC Tracker (20') Fuminori Sakuma (RIKEN)10:10 Optical readout of the ionization (20') Neil Spooner (U. of Sheffield)10:30 Scintillation light readout (20') Kostas Mavrokoridis (U. of Liverpool)10:50-11:10 Coffee break Ways to improve the Liquid Argon Charge Imaging technology II (Chair: Alberto Marchionni (ETH Zurich))11:10 Development of cold electronics (30') Veljko Radeka (BNL)11:40 Development of a frontend ASIC and DAQ system Dario Autiero (IPN Lyon)12:00 CAEN digitizers (20') Carlo Tintori (CAEN)12:20 Recent results from Liquid Argon R&D activity (20') Masashi Tanaka (KEK)12:40 Results from the materials test stand and status of LAPD (20') Brian Rebel (FNAL)13:00 Purging and purification: 6 m3 @CERN (20') Alessandro Curioni (ETH Zurich)13:20-14:30 Lunch break14:30-20:00 Trip to J-PARC to visit T2K Beam Facility and Near Detector20:00-22:00 Workshop dinner at Okura Frontier Hotel Tsukuba Wednesday 31 March 2010Ways to improve the Liquid Argon Charge Imaging technology III (Chair: Takasumi Maruyama (KEK))09:00 ArgonTube and UV laser ionization (25') Biagio Rossi (U. of Bern)09:25 Detector magnetization (15') Andreas Badertscher (ETH Zurich)09:40 HV system (25') Sosuke Horikawa (ETH Zurich) Localization studies (Chair: Takuya Hasegawa (KEK))10:05 Okinoshima site study (20') Masakazu Yoshioka (KEK)10

  12. PREFACE: Strongly correlated electron systems Strongly correlated electron systems

    NASA Astrophysics Data System (ADS)

    Saxena, Siddharth S.; Littlewood, P. B.

    2012-07-01

    make use of 'small' electrons packed to the highest possible density. These are by definition 'strongly correlated'. For example: good photovoltaics must be efficient optical absorbers, which means that photons will generate tightly bound electron-hole pairs (excitons) that must then be ionised at a heterointerface and transported to contacts; efficient solid state refrigeration depends on substantial entropy changes in a unit cell, with large local electrical or magnetic moments; efficient lighting is in a real sense the inverse of photovoltaics; the limit of an efficient battery is a supercapacitor employing mixed valent ions; fuel cells and solar to fuel conversion require us to understand electrochemistry on the scale of a single atom; and we already know that the only prospect for effective high temperature superconductivity involves strongly correlated materials. Even novel IT technologies are now seen to have value not just for novel function but also for efficiency. While strongly correlated electron systems continue to excite researchers and the public alike due to the fundamental science issues involved, it seems increasingly likely that support for the science will be leveraged by its impact on energy and sustainability. Strongly correlated electron systems contents Strongly correlated electron systemsSiddharth S Saxena and P B Littlewood Magnetism, f-electron localization and superconductivity in 122-type heavy-fermion metalsF Steglich, J Arndt, O Stockert, S Friedemann, M Brando, C Klingner, C Krellner, C Geibel, S Wirth, S Kirchner and Q Si High energy pseudogap and its evolution with doping in Fe-based superconductors as revealed by optical spectroscopyN L Wang, W Z Hu, Z G Chen, R H Yuan, G Li, G F Chen and T Xiang Structural investigations on YbRh2Si2: from the atomic to the macroscopic length scaleS Wirth, S Ernst, R Cardoso-Gil, H Borrmann, S Seiro, C Krellner, C Geibel, S Kirchner, U Burkhardt, Y Grin and F Steglich Confinement of chiral magnetic

  13. Two new basaltic objects in the Outer Main Belt

    NASA Astrophysics Data System (ADS)

    Duffard, R.; Roig, F.; Gil-Hutton, R.; Moskovitz, N. A.

    2007-08-01

    ., Florczak, M., Angeli, C.A., and Harris, A.W. 2000. Science 288, 2033. [11] Michtchenko, T.A., Lazzaro, D., Ferraz-Melo, S., and Roig, F. 2002. Icarus 158, 343. [12] Roig, F., and Gil-Hutton, R. 2006. Icarus 183, 411-419. [13]Moskovitz, N. A.; Willman, M.; Lawrence, S. J.; Jedicke, R.; Nesvorny, D.; Gaidos, E. J. 38th Lunar and Planetary Science Conference, (Lunar and Planetary Science XXXVIII), March 12-16, 2007 League City, Texas. LPI Contribution No. 1338, p.1663

  14. PREFACE: XIII International Conference on Calorimetry in High Energy Physics (CALOR 2008)

    NASA Astrophysics Data System (ADS)

    Livan, Michele

    2009-07-01

    Advisory Commitee M Danilov, ITEP Moscow M Diemoz, INFN Roma I A Ereditato, Bern F Fabbri, INFN Frascati T Kobayashi, ICEPP Tokyo P Lubrano, INFN Perugia S Magill, ANL Argonne A Maio, LIP Lisbon H Oberlack, MPI Munich A Para, Fermilab K Pretzl, Bern Y Wang, IHEP Beijing R Wigmans, TTU Lubbock R Yoshida, ANL Argonne R Zhu, Caltech Local Organizing Committee R Ferrari, INFN Pavia M Fraternali, Università di Pavia G Gaudio, INFN Pavia M Livan, Università di Pavia (Chair) P Pedroni, INFN Pavia D A Scannicchio, INFN Pavia V Vercesi, INFN Pavia Session Organizers Operating Calorimeters W Sakumoto (University of Rochester) D Schamberger (State University of NY at Stony Brook) Calorimetric Techniques C De La Taille (Université de Paris-Sud) Paul Lecoq (CERN) Frank Maas (GSI-Mainz University) Jan Stark (LPSC Grenoble) Astrophysics and neutrinos I Gil Botella (CIEMAT) A Vacchi (INFN Trieste) LHC P Bloch (CERN) L Serin (Laboratoire de l'Accelerateur Lineaire/IN2P3/CNRS) New Techniques N Akchurin (Texas Tech University) F Salvatore (Royal Holloway University of London) Simulation T Carli (CERN) A Rimoldi (INFN e Università di Pavia) Organization Dipartimento di Fisica Nucleare e Teorica - Università degli Studi di Pavia Istituto Nazionale di Fisica Nucleare - Sezione di Pavia Università degli Studi di Pavia Pragma Congressi, Corso Mazzini, 9 - Pavia Sponsored by CAEN HAMAMATSU Photonis Italia Iseg Spezialelektrinik GmbH Wiener

  15. FOREWORD: TAUP 2005: Proceedings of the Ninth International Conference on Topics in Astroparticle and Underground Physics

    NASA Astrophysics Data System (ADS)

    Bottino, Alessandro; Coccia, Eugenio; Morales, Julio; Puimedónv, Jorge

    2006-04-01

    qualities, was illustrated. The TAUP Steering Committee recalls with deep gratitude that John Bahcall served continuously as a member of the TAUP International Advisory Committee and that he gave an inspired and brilliant conclusive talk at TAUP 2003 in Seattle. Our astroparticle community will miss him greatly. The TAUP 2005 Organizing Committee thanks Ministerio de Educación y Ciencia, Gobierno de Aragón, Zaragoza University, INFN, IUPAP, PaNAGIC and Ibercaja for sponsoring the Conference, and the Rector and Vice-Rector of the Zaragoza University for their hospitality in the magnificent Paraninfo Palace, where the meeting was held. We wish to thank Venya Berezinsky, José Bernabéu and José Angel Villar for their invaluable contribution in the scientific shaping of the conference and in the preparation of the present volume. Very special thanks are due to Ms Mercedes Fatás and Ms Franca Masciulli, our workshop secretaries, for their continuous and excellent work in the organization of the conference, and to Ms Leopolda Benazzato for her invaluable assistance during the conference. We also gratefully thank the technical staff: Cristina Gil, Francisco Javier Mena and Alfonso Ortiz de Solórzano for their invaluable help. As announced at the end of the conference, TAUP 2007 will be held in Sendai, Japan, hosted by the Tohoku University with the chairs of Professors Atsuto Suzuki and Kunio Inoue. COMMITTEES TAUP STEERING COMMITTEE F. T. Avignone, U. South Carolina B. Barish, CALTECH E. Bellotti, U. Milano/INFN J. Bernabéu, U. Valenciav A. Bottino (chair), U. Torino/INFN V. de Alfaro, U. Torino/INFN T. Kajita, ICRR Tokyo C. W. Kim, JHU Baltimore/KIAS Seoul E. Lorenz U. München V. Matveev, INR Moscow J. Morales, U. Zaragoza D. Sinclair, U. Carleton TAUP 2005 INTERNATIONAL ADVISORY COMMITTEE J. J. Aubert, CNRS Marseille J. Bahcall, U. Princeton M. Baldo-Ceolin, U. Padova/INFN L. Bergström, U. Stockholm R. Bernabei, U. Roma Tor Vergata/INFN A. Bettini, U. Padova/INFN S

  16. Occurrence of springs in massifs of crystalline rocks, northern Portugal

    NASA Astrophysics Data System (ADS)

    Pacheco, Fernando António Leal; Alencoão, Ana Maria Pires

    2002-02-01

    ógicos, así como las desviaciones relacionadas con diferencias en la estructura de la roca y, presumiblemente, en las historias de deformación. Se profundizó en la relación entre la frecuencia de los manantiales y las estructuras de la roca por medio de la Determinación Espectral, que es un modelo introducido en el presente estudio. Los datos de entrada son las frecuencias de los manantiales y la longitud de las fracturas en cada dominio geológico, además de los ángulos entre las direcciones de las fracturas y la orientación actual del campo de tensiones. Los resultados del modelo incluyen las denominadas densidades intrínsecas, parámetro que cuantifica la existencia de manantiales en función de factores como el tipo de fractura y el régimen y edad de deformación asociados. Las densidades mayores (12,2 manantiales por kilómetro de lineamiento) fueron atribuidas a fracturas jóvenes de cizalla causadas por deformación frágil, y las menores (valor 0,1) con fracturas antiguas y dúctiles. La Determinación Espectral también relaciona cada clase de orientación con un parámetro estructural dominante: donde la existencia de fracturas está dominada por el campo actual de tensiones, la clase es paralela a la orientación presente de dicho campo; donde domina la longitud de las fracturas, sigue la dirección de las fallas normales de gran escala que atraviesan la región.

  17. PREFACE: Dynamics of low-dimensional systems Dynamics of low-dimensional systems

    NASA Astrophysics Data System (ADS)

    Bernasconi, M.; Miret-Artés, S.; Toennies, J. P.

    2012-03-01

    Hedgeland, Andrew P Jardine, William Allison, John Ellis and Gil Alexandrowicz Fast emission dynamics in droplet epitaxy GaAs ring-disk nanostructures integrated on SiL Cavigli, S Bietti, M Abbarchi, C Somaschini, A Vinattieri, M Gurioli, A Fedorov, G Isella, E Grilli and S Sanguinetti Assessing the composition of hetero-epitaxial islands via morphological analysis: an analytical model matching GeSi/Si(001) dataR Gatti, F Pezzoli, F Boioli, F Montalenti and Leo Miglio Carbon sp chains in graphene nanoholesIvano E Castelli, Nicola Ferri, Giovanni Onida and Nicola Manini Elastic fields and moduli in defected grapheneRiccardo Dettori, Emiliano Cadelano and Luciano Colombo Tuning the plasmon energy of palladium-hydrogen systems by varying the hydrogen concentrationV M Silkin, R Dìez Muiño, I P Chernov, E V Chulkov and P M Echenique Plasmon tsunamis on metallic nanoclustersA A Lucas and M Sunjic Ab initio characterization of graphene nanoribbons and their polymer precursorsRengin Peköz, Xinliang Feng and Davide Donadio First-principles phonon calculations of Fe4+ impurity in SrTiO3E Blokhin, E A Kotomin and J Maier Phonon dispersion of quasi-freestanding graphene on Pt(111)Antonio Politano, Antonio Raimondo Marino and Gennaro Chiarello Vibrations of Au13 and FeAu12 nanoparticles and the limits of the Debye temperature conceptGhazal Shafai, Marisol Alcántara Ortigoza and Talat S Rahman Triple quantum dots as charge rectifiers M Busl and G Platero

  18. Rock fragment cover controls the sediment detachment in citrus plantations

    NASA Astrophysics Data System (ADS)

    Cerdà, Artemi; Keesstra, Saskia; Hamidreza Sadeghi, Seyed; Brevik, Eric; Giménez Morera, Antonio; Novara, Agata; Masto, Reginald E.; Jordán, Antonio; Wang, Juan

    2016-04-01

    fragment cover on interrill soil erosion from bare soils in Western Andalusia, Spain. Soil Use and Management, 24(1), 108-117. Mwango S. B., Msanya B. M., Mtakwa P. W., Kimaro D. N., Deckers J., Poesen J. 2016. Effectiveness of mulching under miraba in controlling soil erosion, fertility restoration and crop yield in the usambara mountains, Tanzania. Land Degradation and Development, DOI: 10. 1002/ldr. 2332 Nanko K., Giambelluca T. W., Sutherland R. A., Mudd R. G., Nullet M. A., Ziegler A. D. 2015. Erosion potential under miconia calvescens stands on the island of hawai'i. Land Degradation and Development, 26 (3), 218-226. DOI: 10. 1002/ldr. 2200 Ochoa-Cueva, P., Fries, A., Montesinos, P., Rodríguez-Díaz, J.A., Boll, J. 2015. Spatial Estimation of Soil Erosion Risk by Land-cover Change in the Andes OF Southern Ecuador. Land Degradation and Development, 26 (6), 565-573. DOI: 10.1002/ldr.2219 Poesen, J. W., Torri, D., Bunte, K. 1994. Effects of rock fragments on soil erosion by water at different spatial scales: a review. Catena, 23(1), 141-166. Poesen, J., Lavee, H. 1994. Rock fragments in top soils: significance and processes. Catena, 23 (1), 1-28. Zavala, L. M., Jordán, A., Bellinfante, N., Gil, J. 2010. Relationships between rock fragment cover and soil hydrological response in a Mediterranean environment. Soil Science & Plant Nutrition, 56 (1), 95-104. Zhao, C., Gao, J., Huang, Y., Wang, G., Zhang, M. 2015. Effects of Vegetation Stems on Hydraulics of Overland Flow Under Varying Water Discharges. Land Degradation and Development, DOI: 10.1002/ldr.2423

  19. Commentary on "Plasma carotenoids and vitamin C concentrations and risk of urothelial cell carcinoma in the European Prospective Investigation into Cancer and Nutrition." Ros MM, Bueno de Mesquita HB, Kampman E, Aben KK, Büchner FL, Jansen EH, van Gils CH, Egevad L, Overvad K, Tjønneland A, Roswall N, Boutron Ruault MC, Kvaskoff M, Perquier F, Kaaks R, Chang Claude J, Weikert S, Boeing H, Trichopoulou A, Lagiou P, Dilis V, Palli D, Pala V, Sacerdote C, Tumino R, Panico S, Peeters PH, Gram IT, Skeie G, Huerta JM, Barricarte A, Quirós JR, Sánchez MJ, Buckland G, Larrañaga N, Ehrnström R, Wallström P, Ljungberg B, Hallmans G, Key TJ, Allen NE, Khaw KT, Wareham N, Brennan P, Riboli E, Kiemeney LA, National Institute for Public Health and the Environment, Bilthoven, Netherlands: Am J Clin Nutr 2012;96(4):902-10 [Epub 2012 Sep 5].

    PubMed

    See, William A

    2013-07-01

    Published associations between dietary carotenoids and vitamin C and bladder cancer risk are inconsistent. Biomarkers may provide more accurate measures of nutrient status. We investigated the association between plasma carotenoids and vitamin C and risk of urothelial cell carcinoma (UCC) in a case-control study nested within the European Prospective Investigation into Cancer and Nutrition. A total of 856 patients with newly diagnosed UCC were matched with 856 cohort members by sex, age at baseline, study center, date and time of blood collection, and fasting status. Plasma carotenoids (α- and β-carotene, β-cryptoxanthin, lycopene, lutein, and zeaxanthin) were measured by using reverse-phase HPLC, and plasma vitamin C was measured by using a colorimetric assay. Incidence rate ratios (IRRs) were estimated by using conditional logistic regression with adjustment for smoking status, duration, and intensity. UCC risk decreased with higher concentrations of the sum of plasma carotenoids (IRR for the highest compared with the lowest quartile: 0.64; 95% CI: 0.44, 0.93; P-trend = 0.04). Plasma β-carotene was inversely associated with aggressive UCC (IRR: 0.51; 95% CI: 0.30, 0.88; P-trend = 0.02). Plasma lutein was inversely associated with risk of nonaggressive UCC (IRR: 0.56; 95% CI: 0.32, 0.98; P-trend = 0.05). No association was observed between plasma vitamin C and risk of UCC. Although residual confounding by smoking or other factors cannot be excluded, higher concentrations of plasma carotenoids may reduce risk of UCC, in particular aggressive UCC. Plasma lutein may reduce risk of nonaggressive UCC. Copyright © 2013. Published by Elsevier Inc.

  20. The use of straw to reduce the soil and water losses in agriculture and forest ecosystems in the Mediterranean Type-Ecosystem. The Soil Erosion and Degradation Research Group contribution

    NASA Astrophysics Data System (ADS)

    Cerda, Artemi; Burguet, Maria; Keesstra, Saskia; Borja, Manuel Esteban Lucas; Hedo, Javier; Brevik, Eric; Pereira, Paulo; Novara, Agata; Jordan, Antonio; Prosdocimi, Massimo; Taguas, Encarnacion

    2016-04-01

    58-65. doi:10.1016/j.geoderma.2015.11.032 Zavala, L. M., Jordán, A., Bellinfante, N., Gil, J. 2010. Relationships between rock fragment cover and soil hydrological response in a Mediterranean environment. Soil Science & Plant Nutrition, 56 (1), 95-104. Zhao, C., Gao, J., Huang, Y., Wang, G., Zhang, M. 2015. Effects of Vegetation Stems on Hydraulics of Overland Flow Under Varying Water Discharges. Land Degradation and Development, DOI: 10.1002/ldr.2423

  1. Ash wettability conditions splash erosion in the postfire

    NASA Astrophysics Data System (ADS)

    Gordillo-Rivero, Ángel J.; de Celis, Reyes; García-Moreno, Jorge; Jiménez-Compán, Elizabeth; Alanís, Nancy; Cerdà, Artemi; Pereira, Paulo; Zavala, Lorena M.; Jordán, Antonio

    2015-04-01

    -prone ecosystems of the Mediterranean Basin: a phylogenetic approach. Oikos 109, 196-202. Pereira P, Úbeda X, Outeiro L, Martin D. 2009. Factor analysis applied to fire temperature effects on water quality. In: Gómez E, Álvarez K (Eds.), Forest Fires: Detection, Suppression and Prevention. Series Natural Disaster Research, Prediction and Mitigation, Nova Science Publishers, New York, NY. Pp.: 273-285 Pereira P, Cerdà A, Úbeda X, Mataix-Solera J, Martin D, Jordán A, Burguet M. 2013. Spatial models for monitoring the spatio-temporal evolution of ashes after fire - a case study of a burnt grassland in Lithuania. Solid Earth 4, 153-165. Sevink J, Imeson AC, Verstraten JM. 1989. Humus form development and hillslope runoff, and the effects of fire and management, under Mediterranean forest in N.E. Spain. Catena 16, 461-475. Stark NM, 1977. Fire and nutrient cycling in a Douglas-fir/larch forest. Ecology, 58, 16-30. Trabaud L. 2000. Post-fire regeneration of Pinus halepensis forest in the west Mediterranean. In: Ne'eman G, Trabaud L (Eds.), Ecology, biogeography and management of Pinus halepensis and P. brutia forest ecosystems in the Mediterranean basin. Backhuys Publishers. Leiden. Pp.: 257-268. Woods SW, Balfour VN. 2008. Vegetative ash: an important factor in the short term response to rainfall in the post-fire environment. Geophysical Research Abstracts 10, EGU2008-A-00556. Woods SW, Balfour VN. 2010. The effects of soil texture and ash thickness on the post-fire hydrological response from ash-covered soils. Journal of Hydrology 393, 274-286. Zavala LM, Jordán A, Gil J, Bellinfante N, Pain C. 2009. Intact ash and charred litter reduces susceptibility to rain splash erosion post-wildfire Earth Surface Processes and Landforms, 34, 1522-1532. Zavala LM, De Celis R, Jordán A. 2014. How wildfires affect soil properties. A brief review Cuadernos de Investigación Geográfica 40, 311-331. AKNOWLEDGEMENTS This research is part of the POSTFIRE Project (ref. CGL2013-47862-C2-1-R

  2. Thermoelectric Devices: Solid-State Refrigerators and Electrical Generators in the Classroom

    NASA Astrophysics Data System (ADS)

    Winder, Edmund J.; Ellis, Arthur B.; Lisensky, George C.

    1996-10-01

    electrically in series but thermally in parallel. All of the elements move heat from the top to the bottom of the module. Note that all of the metallic conductors are entirely in the plane of the top plate or the bottom plate. All of the elements are connected in series electrically, but they all shunt heat from the top to the bottom of the device. The thermoelectric module shown in Figure 1 has several hundred thermoelements. Conclusion Thermoelectric devices provide an engaging high-tech demonstration suitable for illustrating thermodynamic principles in the classroom. They also showcase an elegant solid-state method of refrigeration, heating, and power generation. Thermoelectric effects can be understood at a qualitative level through the familiar chemical concept of the kinetic molecular theory of gases. The materials used in thermoelectric devices and described herein can be used to introduce a variety of solid-state structures. Insight is also gained into some of the engineering issues that must be considered when bringing a promising technology to the marketplace. Acknowledgments We would like to acknowledge Gil Nathanson, Frank Weinhold, Mark Rzchowski, Frank DiSalvo, Worth Vaughan, and Tom Kuech for helpful discussions, and Ronald Perkins for making us aware of these interesting materials. We are grateful to the National Science Foundation, through the Division of Undergraduate Education and Division of Materials Research, for supporting this work. Notes 1. Thermoelectric modules can be obtained from several other sources: Arbor Scientific (800 367-6695) sells a 1 cm x 1 cm module attached to a heat sink for about 60. It draws 2.5 A of current at 2 V dc. Melcor (609 393-4178), a large manufacturer of thermoelectrics, sells models ranging in size from 1.8 mm x 3.4 mm ( 13) up to 6.2 cm x 6.2 cm ( 70). MacConnection (800 800-1111) sells a 1 in. x 1 in. module designed to cool the CPUs of IBM-compatible PCs for 50 (stock number 19080). 2. Vernier also sells Texas